BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|40353727 synaptopodin isoform A [Homo sapiens] (903 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|40353727 synaptopodin isoform A [Homo sapiens] 1828 0.0 gi|158303333 synaptopodin isoform B [Homo sapiens] 1349 0.0 gi|166706868 synaptopodin 2-like isoform a [Homo sapiens] 147 6e-35 gi|50301232 synaptopodin 2-like isoform b [Homo sapiens] 147 6e-35 gi|193083183 synaptopodin 2 isoform a [Homo sapiens] 119 1e-26 gi|163965366 nascent polypeptide-associated complex alpha subuni... 115 2e-25 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 107 5e-23 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 104 3e-22 gi|193083191 synaptopodin 2 isoform c [Homo sapiens] 101 3e-21 gi|193083185 synaptopodin 2 isoform b [Homo sapiens] 101 4e-21 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 99 2e-20 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 95 3e-19 gi|150170670 piccolo isoform 2 [Homo sapiens] 93 1e-18 gi|150378539 piccolo isoform 1 [Homo sapiens] 93 1e-18 gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 88 4e-17 gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 88 4e-17 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 87 7e-17 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 87 7e-17 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 87 7e-17 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 87 7e-17 gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 84 8e-16 gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 84 8e-16 gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 84 8e-16 gi|160707881 formin 2 [Homo sapiens] 83 1e-15 gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 82 2e-15 gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 82 2e-15 gi|60460889 Myb protein P42POP [Homo sapiens] 79 1e-14 gi|41281612 zinc finger protein 828 [Homo sapiens] 79 2e-14 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 78 4e-14 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 78 4e-14 >gi|40353727 synaptopodin isoform A [Homo sapiens] Length = 903 Score = 1828 bits (4736), Expect = 0.0 Identities = 903/903 (100%), Positives = 903/903 (100%) Query: 1 MEGYSEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQNREAQQSSPAPPPA 60 MEGYSEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQNREAQQSSPAPPPA Sbjct: 1 MEGYSEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQNREAQQSSPAPPPA 60 Query: 61 EVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQNSSE 120 EVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQNSSE Sbjct: 61 EVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQNSSE 120 Query: 121 AQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTSTFSREATLIPSS 180 AQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTSTFSREATLIPSS Sbjct: 121 AQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTSTFSREATLIPSS 180 Query: 181 RPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLAKPPSVVNRTA 240 RPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLAKPPSVVNRTA Sbjct: 181 RPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLAKPPSVVNRTA 240 Query: 241 RPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMM 300 RPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMM Sbjct: 241 RPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMM 300 Query: 301 GQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSSHLKGQAVP 360 GQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSSHLKGQAVP Sbjct: 301 GQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSSHLKGQAVP 360 Query: 361 ASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEP 420 ASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEP Sbjct: 361 ASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEP 420 Query: 421 FALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKG 480 FALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKG Sbjct: 421 FALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKG 480 Query: 481 AELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTP 540 AELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTP Sbjct: 481 AELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTP 540 Query: 541 PASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVP 600 PASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVP Sbjct: 541 PASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVP 600 Query: 601 NLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQ 660 NLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQ Sbjct: 601 NLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQ 660 Query: 661 APRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPP 720 APRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPP Sbjct: 661 APRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPP 720 Query: 721 PLPPPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENP 780 PLPPPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENP Sbjct: 721 PLPPPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENP 780 Query: 781 RPFSPPRAPPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRS 840 RPFSPPRAPPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRS Sbjct: 781 RPFSPPRAPPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRS 840 Query: 841 PLPAPPRPFLYRRSPTDSDVSLDSEDSGAKSPGILGYNICPRGWNGSLRLKRGSLPAEAS 900 PLPAPPRPFLYRRSPTDSDVSLDSEDSGAKSPGILGYNICPRGWNGSLRLKRGSLPAEAS Sbjct: 841 PLPAPPRPFLYRRSPTDSDVSLDSEDSGAKSPGILGYNICPRGWNGSLRLKRGSLPAEAS 900 Query: 901 CTT 903 CTT Sbjct: 901 CTT 903 >gi|158303333 synaptopodin isoform B [Homo sapiens] Length = 685 Score = 1349 bits (3491), Expect = 0.0 Identities = 676/676 (100%), Positives = 676/676 (100%) Query: 1 MEGYSEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQNREAQQSSPAPPPA 60 MEGYSEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQNREAQQSSPAPPPA Sbjct: 1 MEGYSEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQNREAQQSSPAPPPA 60 Query: 61 EVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQNSSE 120 EVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQNSSE Sbjct: 61 EVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQNSSE 120 Query: 121 AQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTSTFSREATLIPSS 180 AQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTSTFSREATLIPSS Sbjct: 121 AQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTSTFSREATLIPSS 180 Query: 181 RPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLAKPPSVVNRTA 240 RPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLAKPPSVVNRTA Sbjct: 181 RPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLAKPPSVVNRTA 240 Query: 241 RPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMM 300 RPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMM Sbjct: 241 RPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMM 300 Query: 301 GQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSSHLKGQAVP 360 GQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSSHLKGQAVP Sbjct: 301 GQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSSHLKGQAVP 360 Query: 361 ASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEP 420 ASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEP Sbjct: 361 ASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEP 420 Query: 421 FALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKG 480 FALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKG Sbjct: 421 FALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKG 480 Query: 481 AELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTP 540 AELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTP Sbjct: 481 AELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTP 540 Query: 541 PASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVP 600 PASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVP Sbjct: 541 PASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVP 600 Query: 601 NLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQ 660 NLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQ Sbjct: 601 NLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQ 660 Query: 661 APRPSFSTRNAGIEAQ 676 APRPSFSTRNAGIEAQ Sbjct: 661 APRPSFSTRNAGIEAQ 676 Score = 52.8 bits (125), Expect = 1e-06 Identities = 68/239 (28%), Positives = 92/239 (38%), Gaps = 31/239 (12%) Query: 638 SPPYGGDISPVSPSRAWSPR--AKQAPRPSFSTRNA---GIEAQDRRES-----LPTSPP 687 SP ++ P S SPR AK P+P+ + A G E RR+S + S Sbjct: 441 SPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSS 500 Query: 688 WTPGASRPPSSLDGWVSPGPWE-----PGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRP 742 TP +R PS P W+ PG S P PP + + + LRP Sbjct: 501 HTPELARCPSPTMSL--PSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPEN-GVLRP 557 Query: 743 ETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRM 802 E +PP + +L + I + SPR+A +P S P P PP P + Sbjct: 558 EPTKQPPYQLRPSLFVLSPIKEPAK--VSPRAASPA--KPSSLDLVPNLPKGALPPSPAL 613 Query: 803 RSPQPARPGSAAVPGA-AFAPIPRSP------LPAGPSSCTSPRSPLPAPPRPFLYRRS 854 P + PG PG + P SP P PS SPR+ PRP R+ Sbjct: 614 PRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRA--KQAPRPSFSTRN 670 >gi|166706868 synaptopodin 2-like isoform a [Homo sapiens] Length = 977 Score = 147 bits (370), Expect = 6e-35 Identities = 157/530 (29%), Positives = 216/530 (40%), Gaps = 86/530 (16%) Query: 233 PSVVNRTARPF--GIQA--PGGTSQMER--SPMLERRHFGEKAPAPQPPSLPDRSPRPQR 286 PS+ NR+ARPF G+Q P TS + R +P G +PAP PP L + P P Sbjct: 461 PSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAP-PPFLSSQGPTPLP 519 Query: 287 HIMSRSPMVERRMMGQRSPASE--------------RRPL--GNFTAPPTYTETLSTAPL 330 S P +P S RP+ G PP + Sbjct: 520 SFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTST 579 Query: 331 ASWVRSPPSYSVLYPSS--------DPKSSHLKGQAVPASKTGILEESMARRGSRKSMF- 381 AS S P P + +P S+ + +VPA++TGIL+E+ RRG+RK MF Sbjct: 580 ASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEA-RRRGTRKQMFR 638 Query: 382 TFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRD-RA 440 E+ K +PNP+LL LVQ DEK R E G EE+ +LGAEA NF Q R + Sbjct: 639 PGKEETKNSPNPELLSLVQNLDEKPR-AGGAESGPEEDALSLGAEACNFMQPVGARSYKT 697 Query: 441 SPAAAEEVVPEWASCLKSPRIQAKPKP----KPNQNLSEA-----------------SGK 479 P + P A P P P P++ L + G+ Sbjct: 698 LPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGR 757 Query: 480 GAELYARRQSRMEKYVIESSSHTPELA---RCPSPTMSLPSSWKYPTNAPGAFRVASR-- 534 G EL+A+RQSR ++YV+E + P L R PSPT SLP SWKY N +A Sbjct: 758 GGELFAKRQSRADRYVVEGTP-GPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPL 816 Query: 535 -SP-----ARTPPASLYHG--YLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPR 586 SP ART P + G P+ G+ + + PYQL+ ++F + P P Sbjct: 817 LSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEV--PPTPGPI 874 Query: 587 AASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDIS 646 A+ K + + + A P+ P+ +P T+ + + S P Sbjct: 875 ASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAP 934 Query: 647 PVSPSRAW----SPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGA 692 P R S Q RP FS G++A W PGA Sbjct: 935 PPEAPRGLGASPSSCGFQVARPRFSATRTGLQAH----------VWRPGA 974 Score = 73.9 bits (180), Expect = 6e-13 Identities = 178/777 (22%), Positives = 256/777 (32%), Gaps = 142/777 (18%) Query: 189 SSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLAKPPSVVNRTARPFGIQAP 248 S+ LID N LV++ R A P + S + P S ++ + P Sbjct: 68 SAMSLIDASGNQLVLTVQ-----RLADEGPVQSPSPHELQVLSPLSPLSPEPPGAPVPQP 122 Query: 249 GGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASE 308 + RSP ++GE P+ ++ RP+R +R S Sbjct: 123 LQPGSL-RSPPDSEAYYGETDSDADGPATQEKPRRPRRRGPTRPTPPGAPPDEVYLSDSP 181 Query: 309 RRPLGNFTAPPTYTETLSTAPLASW-----VRSPPSYSVLYPSSDPKSS-HL-------- 354 P PP+ ++ ++P SW ++ PP+ ++L P + HL Sbjct: 182 AEPAPTIPGPPSQGDSRVSSP--SWEDGAALQPPPAEALLLPHGPLRPGPHLIPMVGPVP 239 Query: 355 -------------KGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQT 401 K + + L+E + K T PNP ++ Sbjct: 240 HPVAEDLTTTYTQKAKQAKLQRAESLQEKSIKEAKTKCR-TIASLLTAAPNPHSKGVLMF 298 Query: 402 ADEKRRQRDQ----------GEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPE 451 +KRRQR + G EEE S +E S A + + Sbjct: 299 --KKRRQRAKKYTLVSFGAAAGTGAEEEDGVPPTSESELDEEAF-----SDARSLTNQSD 351 Query: 452 WAS-CLKSPRIQAKPKPKPNQN------LSEASGKGAELYARRQSRMEKYVIESSSHTPE 504 W S L +A + Q LSE SG+G +L+ +++ R + S T E Sbjct: 352 WDSPYLDMELARAGSRASEGQGSGLGGQLSEVSGRGVQLFEQQRQRAD-------SSTQE 404 Query: 505 LARCPSPTMSLPSSWKYPT---NAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPT- 560 LAR M + P +AP V SP P AS + P G P P+ Sbjct: 405 LARVEPAAMLNGEGLQSPPRAQSAPPEAAVLPPSPLPAPVASP-RPFQPGGGAPTPAPSI 463 Query: 561 -KQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLP-----KGALP-PSPAL 613 + P L P P A A S L P P +G P PS Sbjct: 464 FNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTS 523 Query: 614 PRPSRSSPGLYTSPGQDSLQPTAVSPPY-GGDISPVSPSRAWSPRAKQAPRPSFSTRNAG 672 PS + S + S TA S Y PV+P A P A + ST + Sbjct: 524 GVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTSTASIF 583 Query: 673 IEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGP------------------WEPGRGS 714 + A R + P +P PGA PPS+ + +S + PG+ Sbjct: 584 LSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEE 643 Query: 715 SMSSPPP--------LPPPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAAR 766 + +SP P L P + S L EA +Q + AR+ Sbjct: 644 TKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEA---CNFMQPVGARSYKTLPH 700 Query: 767 RKSASPRSAGAENPRPFSPPRAPPPPPPPP------------------PPPPRM------ 802 +P + P P +P PP P PP P PPR+ Sbjct: 701 VTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGRGGE 760 Query: 803 ----RSPQPARPGSAAVPGAAFAPIPRSPLPA---GPSSCTSP--RSPLPAPPRPFL 850 R + R PG P PRSP P PS SP R+P P P L Sbjct: 761 LFAKRQSRADRYVVEGTPGPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPLL 817 Score = 45.4 bits (106), Expect = 2e-04 Identities = 138/623 (22%), Positives = 207/623 (33%), Gaps = 159/623 (25%) Query: 257 SPMLERRHFGEKAPAPQP-PSLPDRSPRP-QRHIMSRSPMVERRMMGQRSPASERRPLGN 314 +P+ R F AP P PS+ +RS RP + + P + +P LG Sbjct: 442 APVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGG 501 Query: 315 FT-APPTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMAR 373 + APP + + PL S+ PS++ + S P + G P + T Sbjct: 502 LSPAPPPFLSSQGPTPLPSFTSGVPSHAPV--SGSPSTPRSSG---PVTATS-------- 548 Query: 374 RGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPF-----ALGAEAS 428 S++ VTP G E P A+ + AS Sbjct: 549 -----SLYIPAPSRPVTPG----------------------GAPEPPAPPSAAAMTSTAS 581 Query: 429 NFQQEPA-PRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARR 487 F P P R A PE P Q +S + + L R Sbjct: 582 IFLSAPLRPSARPEAPAPGPGAPE-------------PPSAREQRISVPAARTGILQEAR 628 Query: 488 QSRMEKYVIESSSHTPELARCPSPTM-SLPSSWKYPTNAPGAFRVASRSPARTPPASLYH 546 + K + E P+P + SL + A GA A + A + Sbjct: 629 RRGTRKQMFRPGKE--ETKNSPNPELLSLVQNLDEKPRAGGA-ESGPEEDALSLGAEACN 685 Query: 547 GYLPENG---VLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPA--KPSSLDLVPN 601 P P T + P + P K P ++P+ P KP S L+ Sbjct: 686 FMQPVGARSYKTLPHVTPKTPPPMAP--------KTPPPMTPKTPPPVAPKPPSRGLLDG 737 Query: 602 LPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQA 661 L GA S +P P R LQ GG++ SRA + Sbjct: 738 LVNGAAS-SAGIPEPPR-------------LQGR------GGELFAKRQSRADRYVVEGT 777 Query: 662 PRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPPP 721 P P R P SP TP S PPS W+ ++ +PPP Sbjct: 778 PGPGLGPR-------------PRSPSPTP--SLPPS----------WK--YSPNIRAPPP 810 Query: 722 LPPPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRK------------- 768 + P +SP + + + + + +++ P + Q + A + + + Sbjct: 811 IAYNPLLSPFFPQAARTLPKAQSQG-PRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPP 869 Query: 769 ------SASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPA--------RPGSAA 814 S SP++A + R FS P P P P P + +P+ A R A+ Sbjct: 870 TPGPIASGSPKTARVQEIRRFS---TPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELAS 926 Query: 815 VPGAAFAPIPRSP--LPAGPSSC 835 P + AP P +P L A PSSC Sbjct: 927 APVPSPAPPPEAPRGLGASPSSC 949 Score = 37.0 bits (84), Expect = 0.083 Identities = 34/103 (33%), Positives = 39/103 (37%), Gaps = 24/103 (23%) Query: 791 PPPPPPPPPPRMRSPQPARPGSAAVP---------------GAAFAPIPRSPLPAGPSSC 835 P P P PP PQP +PGS P G A PR P GP+ Sbjct: 106 PLSPLSPEPPGAPVPQPLQPGSLRSPPDSEAYYGETDSDADGPATQEKPRRPRRRGPTRP 165 Query: 836 TSPRSP--------LPAPPRPFL-YRRSPTDSDVSLDSEDSGA 869 T P +P PA P P + S DS VS S + GA Sbjct: 166 TPPGAPPDEVYLSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGA 208 >gi|50301232 synaptopodin 2-like isoform b [Homo sapiens] Length = 753 Score = 147 bits (370), Expect = 6e-35 Identities = 157/530 (29%), Positives = 216/530 (40%), Gaps = 86/530 (16%) Query: 233 PSVVNRTARPF--GIQA--PGGTSQMER--SPMLERRHFGEKAPAPQPPSLPDRSPRPQR 286 PS+ NR+ARPF G+Q P TS + R +P G +PAP PP L + P P Sbjct: 237 PSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGGLSPAP-PPFLSSQGPTPLP 295 Query: 287 HIMSRSPMVERRMMGQRSPASE--------------RRPL--GNFTAPPTYTETLSTAPL 330 S P +P S RP+ G PP + Sbjct: 296 SFTSGVPSHAPVSGSPSTPRSSGPVTATSSLYIPAPSRPVTPGGAPEPPAPPSAAAMTST 355 Query: 331 ASWVRSPPSYSVLYPSS--------DPKSSHLKGQAVPASKTGILEESMARRGSRKSMF- 381 AS S P P + +P S+ + +VPA++TGIL+E+ RRG+RK MF Sbjct: 356 ASIFLSAPLRPSARPEAPAPGPGAPEPPSAREQRISVPAARTGILQEA-RRRGTRKQMFR 414 Query: 382 TFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRD-RA 440 E+ K +PNP+LL LVQ DEK R E G EE+ +LGAEA NF Q R + Sbjct: 415 PGKEETKNSPNPELLSLVQNLDEKPR-AGGAESGPEEDALSLGAEACNFMQPVGARSYKT 473 Query: 441 SPAAAEEVVPEWASCLKSPRIQAKPKP----KPNQNLSEA-----------------SGK 479 P + P A P P P P++ L + G+ Sbjct: 474 LPHVTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRLQGR 533 Query: 480 GAELYARRQSRMEKYVIESSSHTPELA---RCPSPTMSLPSSWKYPTNAPGAFRVASR-- 534 G EL+A+RQSR ++YV+E + P L R PSPT SLP SWKY N +A Sbjct: 534 GGELFAKRQSRADRYVVEGTP-GPGLGPRPRSPSPTPSLPPSWKYSPNIRAPPPIAYNPL 592 Query: 535 -SP-----ARTPPASLYHG--YLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPR 586 SP ART P + G P+ G+ + + PYQL+ ++F + P P Sbjct: 593 LSPFFPQAARTLPKAQSQGPRATPKQGIKALDFMRHQPYQLKTAMFCFDEV--PPTPGPI 650 Query: 587 AASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDIS 646 A+ K + + + A P+ P+ +P T+ + + S P Sbjct: 651 ASGSPKTARVQEIRRFSTPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELASAPVPSPAP 710 Query: 647 PVSPSRAW----SPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGA 692 P R S Q RP FS G++A W PGA Sbjct: 711 PPEAPRGLGASPSSCGFQVARPRFSATRTGLQAH----------VWRPGA 750 Score = 69.3 bits (168), Expect = 2e-11 Identities = 115/449 (25%), Positives = 153/449 (34%), Gaps = 82/449 (18%) Query: 473 LSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPT---NAPGAF 529 LSE SG+G +L+ +++ R + S T ELAR M + P +AP Sbjct: 156 LSEVSGRGVQLFEQQRQRAD-------SSTQELARVEPAAMLNGEGLQSPPRAQSAPPEA 208 Query: 530 RVASRSPARTPPASLYHGYLPENGVLRPEPT--KQPPYQLRPSLFVLSPIKEPAKVSPRA 587 V SP P AS + P G P P+ + P L P P A Sbjct: 209 AVLPPSPLPAPVASP-RPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLA 267 Query: 588 ASPAKPSSLDLVPNLP-----KGALP-PSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPY 641 A S L P P +G P PS PS + S + S TA S Y Sbjct: 268 PKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPVTATSSLY 327 Query: 642 -GGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLD 700 PV+P A P A + ST + + A R + P +P PGA PPS+ + Sbjct: 328 IPAPSRPVTPGGAPEPPAPPSAAAMTSTASIFLSAPLRPSARPEAPAPGPGAPEPPSARE 387 Query: 701 GWVSPGP------------------WEPGRGSSMSSPPP--------LPPPPPMSPSWSE 734 +S + PG+ + +SP P L P + S Sbjct: 388 QRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPELLSLVQNLDEKPRAGGAESG 447 Query: 735 RSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPP 794 L EA +Q + AR+ +P + P P +P PP P Sbjct: 448 PEEDALSLGAEA---CNFMQPVGARSYKTLPHVTPKTPPPMAPKTPPPMTPKTPPPVAPK 504 Query: 795 PP------------------PPPPRM----------RSPQPARPGSAAVPGAAFAPIPRS 826 PP P PPR+ R + R PG P PRS Sbjct: 505 PPSRGLLDGLVNGAASSAGIPEPPRLQGRGGELFAKRQSRADRYVVEGTPGPGLGPRPRS 564 Query: 827 PLPA---GPSSCTSP--RSPLPAPPRPFL 850 P P PS SP R+P P P L Sbjct: 565 PSPTPSLPPSWKYSPNIRAPPPIAYNPLL 593 Score = 45.4 bits (106), Expect = 2e-04 Identities = 138/623 (22%), Positives = 207/623 (33%), Gaps = 159/623 (25%) Query: 257 SPMLERRHFGEKAPAPQP-PSLPDRSPRP-QRHIMSRSPMVERRMMGQRSPASERRPLGN 314 +P+ R F AP P PS+ +RS RP + + P + +P LG Sbjct: 218 APVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTSVIFRPLAPKRANDSLGG 277 Query: 315 FT-APPTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMAR 373 + APP + + PL S+ PS++ + S P + G P + T Sbjct: 278 LSPAPPPFLSSQGPTPLPSFTSGVPSHAPV--SGSPSTPRSSG---PVTATS-------- 324 Query: 374 RGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPF-----ALGAEAS 428 S++ VTP G E P A+ + AS Sbjct: 325 -----SLYIPAPSRPVTPG----------------------GAPEPPAPPSAAAMTSTAS 357 Query: 429 NFQQEPA-PRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARR 487 F P P R A PE P Q +S + + L R Sbjct: 358 IFLSAPLRPSARPEAPAPGPGAPE-------------PPSAREQRISVPAARTGILQEAR 404 Query: 488 QSRMEKYVIESSSHTPELARCPSPTM-SLPSSWKYPTNAPGAFRVASRSPARTPPASLYH 546 + K + E P+P + SL + A GA A + A + Sbjct: 405 RRGTRKQMFRPGKE--ETKNSPNPELLSLVQNLDEKPRAGGA-ESGPEEDALSLGAEACN 461 Query: 547 GYLPENG---VLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPA--KPSSLDLVPN 601 P P T + P + P K P ++P+ P KP S L+ Sbjct: 462 FMQPVGARSYKTLPHVTPKTPPPMAP--------KTPPPMTPKTPPPVAPKPPSRGLLDG 513 Query: 602 LPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQA 661 L GA S +P P R LQ GG++ SRA + Sbjct: 514 LVNGAAS-SAGIPEPPR-------------LQGR------GGELFAKRQSRADRYVVEGT 553 Query: 662 PRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPPP 721 P P R P SP TP S PPS W+ ++ +PPP Sbjct: 554 PGPGLGPR-------------PRSPSPTP--SLPPS----------WK--YSPNIRAPPP 586 Query: 722 LPPPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRK------------- 768 + P +SP + + + + + +++ P + Q + A + + + Sbjct: 587 IAYNPLLSPFFPQAARTLPKAQSQG-PRATPKQGIKALDFMRHQPYQLKTAMFCFDEVPP 645 Query: 769 ------SASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPA--------RPGSAA 814 S SP++A + R FS P P P P P + +P+ A R A+ Sbjct: 646 TPGPIASGSPKTARVQEIRRFS---TPAPQPTAEPLAPTVLAPRAATTLDEPIWRTELAS 702 Query: 815 VPGAAFAPIPRSP--LPAGPSSC 835 P + AP P +P L A PSSC Sbjct: 703 APVPSPAPPPEAPRGLGASPSSC 725 >gi|193083183 synaptopodin 2 isoform a [Homo sapiens] Length = 1261 Score = 119 bits (299), Expect = 1e-26 Identities = 109/329 (33%), Positives = 147/329 (44%), Gaps = 51/329 (15%) Query: 469 PNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNA--- 525 P+ L SG+GA+L+A+RQSRMEKYV++S + AR SPT SLP+SWKY +N Sbjct: 861 PSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAP 920 Query: 526 -PGAFR----------VASRSPARTPPASL--YHGYLPENGVLRPEPTKQPPYQLRPSLF 572 P A+ P+ P+ + G P N + + K PYQL SLF Sbjct: 921 PPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNAL---DVMKHQPYQLNASLF 977 Query: 573 VLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPA-------LPRPSRSSPGLYT 625 P + P+ +S S+L + K ALPP P + S S YT Sbjct: 978 TFQP-PDAKDGLPQKSSVKVNSALAM-----KQALPPRPVNAASPTNVQASSVYSVPAYT 1031 Query: 626 SPGQ---DSLQPTAVSP-PYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRES 681 SP ++ P + SP P G SP S + S APRP FS + +G+ Q+ S Sbjct: 1032 SPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFV--APRPKFSAKKSGVTIQESGRS 1089 Query: 682 LPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPPP--LPPPPPMSPSWSERSVSP 739 L PG S PP +S PW S SS P L W + SP Sbjct: 1090 LS-----LPGRSVPPP-----ISTSPWVYQPTYSYSSKPTDGLEKANKRPTPWEAAAKSP 1139 Query: 740 LRPETEARPPSRQLQALLARNIINAARRK 768 L +A P R +Q + N+++AARRK Sbjct: 1140 LGLVDDAFQP-RNIQESIVANVVSAARRK 1167 Score = 49.7 bits (117), Expect = 1e-05 Identities = 100/476 (21%), Positives = 162/476 (34%), Gaps = 91/476 (19%) Query: 473 LSEASGKGAELYARRQSRMEKYVIESSSH----TPELARCPSPTMSLPSSWKYPTNAPGA 528 L + +GKGA ++A+R+ RM++ + TP + + T L ++ Y + Sbjct: 484 LPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKEEES 543 Query: 529 FRV----------ASRSPARTPPASLYHG---------YLPENGVLRPEP--TKQPPYQL 567 R S P + + G +P N +P P QP Sbjct: 544 VRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPATPF 603 Query: 568 RPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSR-SSPGLYTS 626 P+ + SPI + P +A P + + P P P+P+ S P Y S Sbjct: 604 SPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDS 663 Query: 627 PGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSP 686 + + + +S P + + +P F+ + + SL + Sbjct: 664 SERIASRDERISVP------AKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNS 717 Query: 687 PWT--PGASRPPSSLDGWVSPGP----WEPGRGSSMSSPPPLPPPP-----------PMS 729 GA + ++S G + + +PPP+ P P P+S Sbjct: 718 EGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVS 777 Query: 730 PSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAEN-PRPFSPPRA 788 P WS V+P +P A P S + + + I A+ R A N PF P+A Sbjct: 778 PVWSP-GVAPTQP--PAFPTSNPSKGTVVSS-IKIAQPSYPPARPASTLNVAGPFKGPQA 833 Query: 789 PPP----PPPPPPPPPRMRSPQPARPG-SAAVPG-------------------------- 817 P P P + + QP G S +PG Sbjct: 834 AVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTV 893 Query: 818 ---AAFAPIPRSPLPAGPSSCTSPRSPLPAPPRPFLYRRSPTDSDVSLDSEDSGAK 870 AA A P LPA ++ R+P P P SP+ +L S+ S A+ Sbjct: 894 QAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPI---HSPSYPLAALKSQPSAAQ 946 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 115 bits (288), Expect = 2e-25 Identities = 212/874 (24%), Positives = 306/874 (35%), Gaps = 130/874 (14%) Query: 55 PAPPPAEVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSLPLSSI 114 P P A + P A QN +P ATL + P + PPA P + + I Sbjct: 699 PLVPTASENCPVAPSPQNTCAPLATLVL----APEIPKSVPSPSLPPAGTPPGTKKVDGI 754 Query: 115 QQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTSTFSREA 174 S+ A + S+ P P+ D A A T L D S + S ++ Sbjct: 755 SHTSALAPVASS---PKECPT---EDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRP 808 Query: 175 TLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTL--AKP 232 S P D +L + P + +S + + +P +S + A Sbjct: 809 PTKKGSAGP--DTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPT 866 Query: 233 PSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAPAP-QPPSLPDRSPRPQRHIMSR 291 PS V + P G+ P + L G PAP Q P+L S P++ + Sbjct: 867 PSAVTPLS-PKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATP 925 Query: 292 SPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSSDPKS 351 +P SP+ + P PP+ +T P W +PP+ + P P + Sbjct: 926 APKGI-----PASPSPKGAPTPPAATPPSPKGGPAT-PSPKWAPTPPAATPPSPKGGPAT 979 Query: 352 SHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQ 411 KG P + T + S K T P VTP T K Sbjct: 980 PSPKGAPTPPAATPPSPKGGPATPSPKGAPT---PPAVTPPSPKGSPAATPFPKGASTPP 1036 Query: 412 GEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQ 471 P G+ A+ + AP A+ + + P S +P A P P Sbjct: 1037 AAT----PPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKG 1092 Query: 472 NLSEASGKGAELYARRQSRMEKYVIESSSH----TPELARCPSPT--MSLPSSWKYPTN- 524 + S KGA + K + + H T A PSP ++ P PT Sbjct: 1093 GPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTP 1152 Query: 525 -----------APGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQP--PYQLRPSL 571 A + A +PA TPP+ P+ G+ P P P P PS Sbjct: 1153 AATPPSPKGGLATPPPKGAPTTPAATPPS-------PKGGLATPSPKGAPTTPAATPPSP 1205 Query: 572 --FVLSPIKEPAKVSPRAASPA------------KPSSLDLVPNLPKG--ALPPSPALPR 615 + +P + A +P A P+ P++ P PKG A PP P Sbjct: 1206 KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPT 1265 Query: 616 PSRSSP-----GLYTSPGQDSLQPTAVSP--PYGGD-------------ISPVSPSRA-W 654 P ++P GL T P + + P V+P P GG +P SP + Sbjct: 1266 PPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPG 1325 Query: 655 SPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPG-------- 706 +P K AP P T + +LP + P + G PSS +G P Sbjct: 1326 TPPPKGAPTPPAVTP----PSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGG 1381 Query: 707 ----PWEPGRGSSMSSP----------PPLPPPPPMSPSWSERSVSPLRPETEARPPSRQ 752 P P RG ++ SP P P P +P E + +P + + PP+ Sbjct: 1382 PAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATP--SKGDLTPPAVT 1439 Query: 753 LQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPAR-PG 811 +L +A + A+P S G P P PP P PP P S P + P Sbjct: 1440 PVSLKKAPATSAPKGGPATPSSKG----DPTLPAVTPPSPKEPPAPKQVATSSSPKKAPA 1495 Query: 812 SAAVPGAAFAP--IPRSP--LPAGPSSCTSPRSP 841 + A GA P IP SP +PA PSS P +P Sbjct: 1496 TPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAP 1529 Score = 92.8 bits (229), Expect = 1e-18 Identities = 207/860 (24%), Positives = 296/860 (34%), Gaps = 101/860 (11%) Query: 59 PAEVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQNS 118 PA PA+ + +P A T P+ P+ PPA P S + Sbjct: 925 PAPKGIPASPSPKGAPTPPAA-TPPSPKGGPATPSPKWAPTPPAAT-PPSPKGGPATPSP 982 Query: 119 SEAQLPSNGTGPASK--PSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTSTFSREATL 176 A P T P+ K P+T G P PA +PA T F + A+ Sbjct: 983 KGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPK------GSPAATP--FPKGAST 1034 Query: 177 IPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLAKPPSVV 236 P++ PP+ S + A S + TP+ + A PPS Sbjct: 1035 PPAATPPSPK--GSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTP-PAATPPSPK 1091 Query: 237 NRTARPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQP--PSLPDRSPRPQRHIMSRSPM 294 A P AP + SP G A P P+ P +P + ++ P Sbjct: 1092 GGPATPSPKGAPMPPAATPPSPK------GGLATPPHKGAPTTPAATPPSPKGGLATPPP 1145 Query: 295 VERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSSHL 354 +P S P G PP + T P A+ PPS + PK + Sbjct: 1146 KGAPTTPAATPPS---PKGGLATPPP--KGAPTTPAAT----PPSPKGGLATPSPKGAPT 1196 Query: 355 KGQAVPASKTGILEESMARRGSRKSMFTFVEKPK---VTPNPDLLDLVQTA---DEKRRQ 408 A P S G L + + +G+ + PK TP+P A K Sbjct: 1197 TPAATPPSPKGGLA-TPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGP 1255 Query: 409 RDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPK-- 466 G P A P + +PA P+ P+ P Sbjct: 1256 ATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAA 1315 Query: 467 --PKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTN 524 P P + KGA K + TP P+ PSS + PT Sbjct: 1316 TPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTT----PSSKEGPT- 1370 Query: 525 APGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVS 584 P A PA TPP+ P+ G P P P P++ LSP K PA Sbjct: 1371 PPAATPSHKGGPAMTPPS-------PKRGPAIPSPKGDPT---SPAVIPLSPKKAPATPV 1420 Query: 585 PRAASPAKPSSLDLVPN-LPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGG 643 R + A PS DL P + +L +PA P + P +S G +L AV+PP Sbjct: 1421 TREGA-ATPSKGDLTPPAVTPVSLKKAPATSAP-KGGPATPSSKGDPTLP--AVTPP--- 1473 Query: 644 DISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSP---PWTPGASRPP---- 696 SP P +P+ + +T A + A +P+SP P TP + R P Sbjct: 1474 --SPKEPPAPKQVATSSSPKKAPATP-APMGAPTLPAVIPSSPKEVPATPSSRRDPIAPT 1530 Query: 697 SSLDGWVSPGPWEPGRG--------SSMSSPPPLPPPP--PMSPSWSERSVSP-LRPETE 745 ++L +P P S P +P P P +PS E S P + P T Sbjct: 1531 ATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTY 1590 Query: 746 ARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSP 805 PS + + L+ + + + +++ +P + +P AP P PP P Sbjct: 1591 KGAPSPK-ELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKD 1649 Query: 806 QPARPGSAAVPGAAFAPIPRSPLPA--GPSS------CTSPRSP--LPAPPR--PFLYRR 853 P P S A P LPA GP++ +P S + AP R P + Sbjct: 1650 SPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKS 1709 Query: 854 SPTDSDVSLD-SEDSGAKSP 872 S T + D S +G+K P Sbjct: 1710 SATSPPICPDPSAKNGSKGP 1729 Score = 88.6 bits (218), Expect = 2e-17 Identities = 202/876 (23%), Positives = 310/876 (35%), Gaps = 184/876 (21%) Query: 77 SATLTTPTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQN----SSEAQLPSNGTGPA- 131 S+T + S S PP N+ PATV + S+ + SS PS A Sbjct: 344 SSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVAT 403 Query: 132 ----SKPSTLCADGQPQA----------PAEEVRCSTLLIDKVSTPATTTSTFSREATLI 177 S ++L P A P V + L++ T A +T AT + Sbjct: 404 SFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCV 463 Query: 178 PSSRPPASDFMSSSLLIDIQPNT---LVVS--ADQEMSGRAAATT----------PTKVY 222 PP MSS + +I+P + LV++ A +E S + A T P + Sbjct: 464 S---PP----MSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLK 516 Query: 223 SEVHFTLAKPPSVVNRTARPFGIQ-APGGTSQMERSPMLERRHFGEKAPAPQ-PPSLPDR 280 + L K P+ + P ++ AP +Q + + AP+ PS Sbjct: 517 NLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQST 576 Query: 281 SPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSY 340 S P+ + + + ++ +G+ P +P + T+P + S S Sbjct: 577 SSSPEIPLSPEATLA-KKSLGEPLPIG--KPASSMTSPLGVNSSASVIKTDS-------- 625 Query: 341 SVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQ 400 Y D LK + + ES G + T +P L V Sbjct: 626 ---YAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVS 682 Query: 401 TADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPR 460 A + ++ + P A + N P+P++ +P A + PE + SP Sbjct: 683 LAPKNHPVKEGTLTTLPLVPTA----SENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPS 738 Query: 461 IQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWK 520 + P + ++ SHT LA P S P + Sbjct: 739 LPPAGTPPGTKK-----------------------VDGISHTSALA----PVASSPK--E 769 Query: 521 YPTNAPGAFRVASRSPARTPPASLYHGYLPEN----GVLRPEPTKQPPYQLRPSLFVLSP 576 PT GA AS T YL ++ GV TK+PP + + S +P Sbjct: 770 CPTEDSGASATASSKGTLT--------YLADSPSPLGVSVSPQTKRPPTK-KGSAGPDTP 820 Query: 577 IKE-PAKVSPRAASPAKPSSLDL-------------VPNLPKGALPPSPALPRPSRSSPG 622 I + VSP AS +SL P PKGA PS P SP Sbjct: 821 IGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPL----SPK 876 Query: 623 LYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAG-IEAQDRRES 681 T P +++ P+ V+ P+ + P +P+ KQAP S ++ + A + Sbjct: 877 GVTLPPKETPTPSVVNLPFPKE-GPATPA------PKQAPALSMTSSSPKKARATPAPKG 929 Query: 682 LPTSPPW----TPGASRPPSSLDGWVSPGP-WEPGRGSSMSSPPPLPPPPPMSPSWSERS 736 +P SP TP A+ PPS G +P P W P +PP PP P Sbjct: 930 IPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP-------TPPAATPPSPKG------- 975 Query: 737 VSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPR--PFSP-PRAPPPPP 793 P P + P +P +A +P+ P +P P+ P PP Sbjct: 976 -GPATPSPKGAP----------------------TPPAATPPSPKGGPATPSPKGAPTPP 1012 Query: 794 PPPPPPPRMRSPQPARPGSAAVPGAAFAPIPR-----SPLPAGPSSCTSPRSPLPAP--- 845 PP P+ P A+ P AA P P+ +PLP G + T+P + LP+P Sbjct: 1013 AVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKG--APTTPAATLPSPKGG 1070 Query: 846 PRPFLYRRSPTDSDVSLDSEDSGAKSPGILGYNICP 881 P + +PT + S G +P G + P Sbjct: 1071 PATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPP 1106 Score = 83.2 bits (204), Expect = 1e-15 Identities = 206/904 (22%), Positives = 302/904 (33%), Gaps = 136/904 (15%) Query: 56 APPPAEVHSPAADVNQNLA--SPSATL-------TTPTSNSSHNPPAT--DVNQNPPATV 104 A PP+ SPAA A +P+ATL TP+ + PPA + PAT Sbjct: 1038 ATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATP 1097 Query: 105 VPQSLPLSSIQQNSSE----AQLPSNG--TGPASKPSTLCADGQPQAPAEEVRCSTLLID 158 P+ P+ S A P G T PA+ P + G P + +T Sbjct: 1098 SPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPS--PKGGLATPPPKGAPTTPAAT 1155 Query: 159 KVSTPATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSG------R 212 S + + A P++ PP+ ++ P T + G + Sbjct: 1156 PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1215 Query: 213 AAATTPTKVYSEVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERS----PMLERRHFGEK 268 A TTP A PPS A P AP + S P Sbjct: 1216 GAPTTPA----------ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPT 1265 Query: 269 APAPQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTA 328 PA PPSL P H + +P V + PA+ P G T P + + Sbjct: 1266 PPAATPPSLKGGLATPP-HKGAPNPAVVTPPSPKGGPATS-PPKGAPTPPAATPPSPKGS 1323 Query: 329 PLASWVRSPPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPK 388 P + P+ + P S PK + P+SK G S ++ G P Sbjct: 1324 PGTPPPKGAPTPPAVTPPS-PKGTPTLPATTPSSKGGPTTPS-SKEGP--------TPPA 1373 Query: 389 VTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEV 448 TP+ + KR G P + P R+ A+ + ++ Sbjct: 1374 ATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDL 1433 Query: 449 VPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRME----KYVIESSS---- 500 P + + + A PK + G S E K V SSS Sbjct: 1434 TPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKA 1493 Query: 501 -HTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEP 559 TP P+ +PSS K P +SR P A+L P L P+ Sbjct: 1494 PATPAPMGAPTLPAVIPSSPKEVPATP-----SSRRDPIAPTATLLSKKTP--ATLAPKE 1546 Query: 560 TKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLD------LVPNLPKGALPPSPAL 613 P P++ V SP K PA +P+ A PA PSS + + P+ KGA P L Sbjct: 1547 ALIP-----PAMTVPSPKKTPAIPTPKEA-PATPSSKEASSPPAVTPSTYKGAPSPKELL 1600 Query: 614 PRPSRSSPGLYTSPGQDSLQPTAVSP--PYGGDISPVSPSRAWSPRAKQAPRPSFSTRNA 671 P+ +SP +P P AV+P P G +P SP + T A Sbjct: 1601 IPPAVTSPSPKEAP-----TPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPA 1655 Query: 672 GIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWE-----------PGRGSSMSSPP 720 + + ++P + P P + + V+P P P S ++ P Sbjct: 1656 SVTCK-MGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSP 1714 Query: 721 PLPP----------------PPPMSPSWSERSVSPL------RPETEARPPSRQLQALLA 758 P+ P P P+ P + S + P+ PP + L Sbjct: 1715 PICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLT 1774 Query: 759 RNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPP------PPPPRMRSPQPARPGS 812 K S + A +P P S P AP P P P P P + P++P + Sbjct: 1775 AAAFEKVLPKPESASVSAAPSP-PVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLA 1833 Query: 813 AAVPGAAFAPIPRSPLPAGPS------SCTSPRS---PLPAPPRPFLYRRSPTDSDVSLD 863 A IP P+ G + +P+S P+P P ++ S D Sbjct: 1834 PADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESD 1893 Query: 864 SEDS 867 S++S Sbjct: 1894 SDES 1897 Score = 60.5 bits (145), Expect = 7e-09 Identities = 161/713 (22%), Positives = 239/713 (33%), Gaps = 163/713 (22%) Query: 41 GLHLSQNREAQQSSPAPPPAEVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNP 100 GL ++ A + PP+ PA + +P A T P+ S P P Sbjct: 1277 GLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAA-TPPSPKGSPGTPPPKGAPTP 1335 Query: 101 PATVVPQSLPLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKV 160 PA P T PA+ PS + G P P+ + + Sbjct: 1336 PAVTPPSP---------------KGTPTLPATTPS---SKGGPTTPSSK--------EGP 1369 Query: 161 STPATTTSTFSREATLIPSSR-----PPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAA 215 + PA T S A PS + P +S +I + P A R A Sbjct: 1370 TPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPK----KAPATPVTREGA 1425 Query: 216 TTPTKVYSEVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPP 275 TP+K PP+V P ++ TS + P PA PP Sbjct: 1426 ATPSK-------GDLTPPAVT-----PVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPP 1473 Query: 276 SLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLASWVR 335 S P P P++ S SP +++PA+ P+G T P + P R Sbjct: 1474 S-PKEPPAPKQVATSSSP--------KKAPATP-APMGAPTLPAVIPSSPKEVPATPSSR 1523 Query: 336 SPPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDL 395 P + P++ S K A A K ++ +M V PK TP Sbjct: 1524 RDP----IAPTATLLSK--KTPATLAPKEALIPPAMT-----------VPSPKKTP---- 1562 Query: 396 LDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASC 455 + T E E P A+ S ++ P+P++ P A P+ Sbjct: 1563 --AIPTPKEAPATPSSKEA---SSPPAV--TPSTYKGAPSPKELLIPPAVTSPSPK---- 1611 Query: 456 LKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSL 515 ++P A P P + + + KG P+ Sbjct: 1612 -EAPTPPAVTPPSPEKGPATPAPKGT---------------------------PTSPPVT 1643 Query: 516 PSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLS 575 PSS K +P + V + A P AS + P K+ P L+ L + Sbjct: 1644 PSSLKDSPTSPAS--VTCKMGATVPQAS------------KGLPAKKGPTALKEVLVAPA 1689 Query: 576 PIKEPAKVSPRAASP-AKPSSLDLVPNLP--------KGAL---PPSPALPRPSRSSPGL 623 P P +P P K SS P P KG L P+P LP SS Sbjct: 1690 PESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSK-- 1747 Query: 624 YTSPGQDSLQPT--AVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRES 681 T+ G+D+ ++PP +P++ + K P+P ++ +A A S Sbjct: 1748 -TAKGKDASHSPKGPLAPPESKASTPLTAAAF----EKVLPKPESASVSA---APSPPVS 1799 Query: 682 LPTSPPWTPGASRPPS-----SLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMS 729 LP +P +P + PP S G V P +P + PL PP P+S Sbjct: 1800 LPLAP--SPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPIS 1850 Score = 42.7 bits (99), Expect = 0.002 Identities = 193/874 (22%), Positives = 296/874 (33%), Gaps = 153/874 (17%) Query: 64 SPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPP----ATVVPQSLPLSSIQQNSS 119 S A V L P TL P S + P + NQ P +T+ L + Q+SS Sbjct: 29 SSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVP-FPQSSS 87 Query: 120 EAQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTSTFSREATLIPS 179 LP GT P + G P +PA S ++ + ++++ + A L P Sbjct: 88 GTALPL-GTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVA-LAPH 145 Query: 180 SRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLAKPPSVVNRT 239 S +S F + L P ++ V+ + +A P SE L K PS V Sbjct: 146 SVQKSSAFPPNLLT---SPPSVAVAESGSVITLSAPIAP----SEPKTNLNKVPSEV--- 195 Query: 240 ARPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRM 299 + P GT P PP + P H ++ ++ Sbjct: 196 -----VPNPKGT--------------------PSPPCIVSTVPY---HCVTPMASIQ--- 224 Query: 300 MGQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSSHLKGQAV 359 + P T T + A + V+ SVL +P S LKG Sbjct: 225 -------------SGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVS 271 Query: 360 PASKTGILEESMARRGSRKSMFTFVEKPKVTPN--PDLLDLVQTADEKRRQRDQGEVGV- 416 P + + +S+ + T +K PN PD + + Q G V + Sbjct: 272 PPAALSLSTQSL-------PVVTSSQK-TAGPNTPPDFPISLGSHLAPLHQSSFGSVQLL 323 Query: 417 -EEEPFALG---------AEASNFQQEPAPRDRASP-AAAEEVVPEWASCL--------K 457 + P AL +S P+ R P + EVVP + K Sbjct: 324 GQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDK 383 Query: 458 SPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCP-SPTMSLP 516 P + P+ +L+ A+ + S + K ++ H P +A+ P S + P Sbjct: 384 GPSTISSITCSPSGSLNVATSFS---LSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTP 440 Query: 517 SSWKYPTNAPGA----FRVAS--RSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPS 570 P A F VA+ P + P S P V+ P K+P Q+ + Sbjct: 441 LVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATT 500 Query: 571 LF--VLSPIKEP--AKVSPRAASPAKPSSLDL--VPNLPKGALPPSPALPRPSRSSPGLY 624 L V P+ +P K P + P+ DL VP +GA P SPA GL Sbjct: 501 LRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGA-PFSPA-------QAGLT 552 Query: 625 TSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPT 684 T L +P SP S + SP +P + + ++ G + + Sbjct: 553 TKKDPTVLPLVQAAPKN----SPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSM 608 Query: 685 SPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPP----PLPPPPP--MSPSWSERSVS 738 + P +S D + P P SS+ +P PL P ++P+ ++ + + Sbjct: 609 TSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTST 668 Query: 739 PLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPP- 797 T A P +L +N P G P P + P P P Sbjct: 669 ---YTTTASPFLEGTVSLAPKN----------HPVKEGTLTTLPLVPTASENCPVAPSPQ 715 Query: 798 ---PPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAPPRPFLYRRS 854 P P P S P A P S TS +P+ + P + Sbjct: 716 NTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSP-----KEC 770 Query: 855 PT-DSDVSLDSEDSG-----AKSPGILGYNICPR 882 PT DS S + G A SP LG ++ P+ Sbjct: 771 PTEDSGASATASSKGTLTYLADSPSPLGVSVSPQ 804 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 107 bits (267), Expect = 5e-23 Identities = 175/654 (26%), Positives = 238/654 (36%), Gaps = 94/654 (14%) Query: 268 KAPAPQPPSL----PDRSPRPQRHIMSRSPMV--ERRMMGQRSPASERRPLGNFTAP--- 318 + PA + P L P SPRP + + V +G++ A +G T P Sbjct: 15 RTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESA 74 Query: 319 PTYTETLSTAPLASW--VRSPPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGS 376 P T ++ P AS R+PP+ + S P SS G+A ++ G L ++G Sbjct: 75 PRAGPTRTSRPPASGRGERAPPAKNT---SPGPVSS--PGRASGTTRPGPL----GQKGL 125 Query: 377 RKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQ---QE 433 R S V + K T P L A RR G A + A+ + Sbjct: 126 RISAEETVARGKATEAPKRSALSAGA---RRDTSGPTPGTPSPAMARRSRAAGTEVGLPR 182 Query: 434 PAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEK 493 PAP R P + S + +P P ++G G + A R Sbjct: 183 PAPSARPRPPTEGP-----RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL---- 233 Query: 494 YVIESSSHTP--ELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTPP---ASLYHGY 548 SSS TP AR P + +P+ A R P TPP A+ G Sbjct: 234 ----SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP 289 Query: 549 LPENGVLRPEPTKQPPYQLRPSLFVLS--PIKEPAKVSPRAASPAKPSSLDLVPNLPKGA 606 L + + P P+ P PSL L P P++ + SP ++ +P+ P Sbjct: 290 LSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP 349 Query: 607 LPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQA---PR 663 L P P+ + P L P SPP +SP++ +P A Sbjct: 350 LATPPPQAPPALALPPLQAPP----------SPPASPPLSPLATPSPQAPNALAVHLLQA 399 Query: 664 PSFSTRNAGIEAQDRRESLPTSPPWTPGASRP---PSSLDG---WVSPGPWEPGRGSSMS 717 P + ++A S P SPP +P A+ P P SL V P P S + Sbjct: 400 PFSPPPSPPVQAPF---SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA 456 Query: 718 SPPPLPPPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGA 777 +PPP PPP +P P P A PP LQAL SP A Sbjct: 457 TPPPQAPPPLAAPPLQLAKPPPQAPPALATPP---LQAL-------------PSP-PASF 499 Query: 778 ENPRPFSPPRAPPPPP---PPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSS 834 PFSP + P P PPP PP + +P P S AP R P P +S Sbjct: 500 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP-RRPPTPGPDTS 558 Query: 835 CTSPRSPL---PAPPRPFLYRRSPTDSDVSLDSEDSGAKS--PGILGYNICPRG 883 + PR L P PP P S T S L S A S + GY+ P G Sbjct: 559 VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 612 Score = 87.4 bits (215), Expect = 5e-17 Identities = 162/695 (23%), Positives = 226/695 (32%), Gaps = 107/695 (15%) Query: 179 SSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPT--------KVYSEVHFTLA 230 +SRPPAS + P GRA+ TT ++ +E Sbjct: 82 TSRPPASGRGERA-----PPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARG 136 Query: 231 KPPSVVNRTARPFGIQAP-GGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIM 289 K R+A G + G + SP + RR P P PRP Sbjct: 137 KATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 196 Query: 290 SRS-PMVERRMMGQRSPASERRPL--GNFTAPPTYTETLSTAPLASWVRSPPSY-----S 341 +S + SPA+ RRP G P + + + S PL+S RS PS + Sbjct: 197 RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA 256 Query: 342 VLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQT 401 +PS PK L+ P + + R+ + ++ P TP+P Sbjct: 257 PAHPSQ-PKPKGLQALRPP-------QVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSA 308 Query: 402 ADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRI 461 + + +LG+ P SP A P+ L P + Sbjct: 309 PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP--PQAPPALALPPL 366 Query: 462 QAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKY 521 QA P P + LS + + + + +++++ P PSP + P S Sbjct: 367 QAPPSPPASPPLSPLATPSPQA----PNALAVHLLQAPFSPP-----PSPPVQAPFS--- 414 Query: 522 PTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPA 581 P +P SP+ TPP+ P PP Q+ PS P+ A Sbjct: 415 PPASPPV------SPSATPPSQA------------PPSLAAPPLQVPPSPPASPPMSPSA 456 Query: 582 KVSPRAASPAKPSSLDLVPNLPKG----ALPPSPALPRPSRSSPGL--YTSPGQDSLQPT 635 P+A P L L P+ A PP ALP P S PG ++ + P Sbjct: 457 TPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 516 Query: 636 AVSPPYG-----GDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTP 690 A PP + V PS SP + RP + + +L PP P Sbjct: 517 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP--P 574 Query: 691 GASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEARPPS 750 SR PSS GP G SS +S P P + P E A P+ Sbjct: 575 PPSRSPSS----TLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPA 630 Query: 751 RQLQALLARNIINAARRKSASPRS-AGAEN-PRPFSPPRAPP-------------PPPPP 795 A R A P + GA P P+ P P P Sbjct: 631 -------------AWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESAT 677 Query: 796 PPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPA 830 P P P P G A GA RSP A Sbjct: 678 PAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQA 712 Score = 60.8 bits (146), Expect = 5e-09 Identities = 89/332 (26%), Positives = 116/332 (34%), Gaps = 80/332 (24%) Query: 578 KEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAV 637 ++ AK A +PA + L P P PP P P R G + G+ L A Sbjct: 5 RDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVL-GAAGAVGRKPLAERAG 63 Query: 638 SPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPS 697 GG P S RA R + P A R E P + +PG P Sbjct: 64 G--IGGATIPESAPRAGPTRTSRPP------------ASGRGERAPPAKNTSPGPVSSPG 109 Query: 698 SLDGWVSPGPW-----------EPGRGSSMSSPPPL------------PPPPPMSPSWSE 734 G PGP RG + +P P P SP+ + Sbjct: 110 RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMAR 169 Query: 735 RS------VSPLRPETEARP------PSRQLQALLARNIIN---AARRK----------- 768 RS V RP ARP P + + + + AARR+ Sbjct: 170 RSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA 229 Query: 769 ------SASPRSAGAEN-PRPFSPPRAPPPPPPPPPPP-PRMRSPQPARPGSAAVPGAAF 820 SA+P S+ A + P PRAP P P P +R PQ P A P A Sbjct: 230 SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAP--AL 287 Query: 821 APIPRSPL----PAGPSSCTSPRS--PLPAPP 846 P+ SPL P+ P S ++P S LP+PP Sbjct: 288 GPLSSSPLATPSPSAPPSPSAPPSLQTLPSPP 319 Score = 41.2 bits (95), Expect = 0.004 Identities = 73/316 (23%), Positives = 104/316 (32%), Gaps = 39/316 (12%) Query: 50 AQQSSPAPP------PAEVHSPAADVNQNL----ASPSATLTTPTSNSSHNPPATDVNQN 99 A S P P P +V P D L +SP AT + S PP+ + Sbjct: 258 AHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPS 317 Query: 100 PPATVVPQ-SLPLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLID 158 PPAT Q + L S ++ + LPS P + P PQAP L + Sbjct: 318 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP-------PPQAP------PALALP 364 Query: 159 KVSTPATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTP 218 + P + ++ PS + P + + P + V A + Sbjct: 365 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 424 Query: 219 TKVYSEVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQ-PPSL 277 S+ +LA PP V + +P T + P L P PQ PP+L Sbjct: 425 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL 484 Query: 278 P----DRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLASW 333 P P ++P SP S P+ PP + APL Sbjct: 485 ATPPLQALPSPPASFPGQAPF---------SP-SASLPMSPLATPPPQAPPVLAAPLLQV 534 Query: 334 VRSPPSYSVLYPSSDP 349 SPP+ L P Sbjct: 535 PPSPPASPTLQAPRRP 550 Score = 40.8 bits (94), Expect = 0.006 Identities = 36/115 (31%), Positives = 46/115 (40%), Gaps = 8/115 (6%) Query: 765 ARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPA---RPGSAAVPGAAFA 821 A ++ + R+ G PRP PR PPPP P R+ A +P + G A Sbjct: 12 AAARTPAARAPGLLTPRPPGSPR---PPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68 Query: 822 PIPRSPLPAGPSSCTSPRSPLPAPPRPFLYRRSPTDSDVSLDSEDSGAKSPGILG 876 IP S AGP+ + P + P SP VS SG PG LG Sbjct: 69 TIPESAPRAGPTRTSRPPASGRGERAPPAKNTSP--GPVSSPGRASGTTRPGPLG 121 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 104 bits (260), Expect = 3e-22 Identities = 183/767 (23%), Positives = 268/767 (34%), Gaps = 118/767 (15%) Query: 163 PATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPT--- 219 P + T SR P+SRPPAS + P GRA+ TT Sbjct: 79 PTRSAGTSSRN----PASRPPASGRGERA-----PPAKNTSPGPVSSPGRASGTTRPGPL 129 Query: 220 -----KVYSEVHFTLAKPPSVVNRTARPFGIQAP-GGTSQMERSPMLERRHFGEKAPAPQ 273 ++ +E K R+A G + G + SP + RR Sbjct: 130 GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189 Query: 274 PPSLPDRSPRPQRHIMSRS-PMVERRMMGQRSPASERRPL--GNFTAPPTYTETLSTAPL 330 P P PRP +S + SPA+ RRP G P + + + S PL Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249 Query: 331 ASWVRSPPSY-----SVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVE 385 +S RS PS + +PS PK L+ P + + R+ + ++ Sbjct: 250 SSPARSGPSARGTPRAPAHPSQ-PKPKGLQALRPP-------QVTPPRKDAAPALGPLSS 301 Query: 386 KPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEAS--------NFQQEPAPR 437 P TP+P P A + + Q P+P Sbjct: 302 SPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPP 361 Query: 438 --------------DRASPAAAEEVVP-EWASCLKSPRIQAKPKPKPNQNLSEASGKGAE 482 +P + + + P + L SP +QA P P +L + G+ Sbjct: 362 ATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSP 421 Query: 483 LYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVA-----SRSPA 537 S ++ S T PS S P P AP + + S SPA Sbjct: 422 TLQATHS----FLTMSPRQTQASLTSPSRPASTPPD-SPPLQAPLSLPASPPLQTSLSPA 476 Query: 538 RTPPAS--LYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSS 595 +P +S H + + P + P L S + P+ +P A+ P Sbjct: 477 VSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPP-- 534 Query: 596 LDLVPNL--------------PKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPY 641 L+ +P+L P PP PA P P ++ P T+P ++ P++++ P Sbjct: 535 LENLPSLAPPPLQTASAPLTTPHLETPPCPA-PCPLQAPPSPLTTPPPET--PSSIATP- 590 Query: 642 GGDISPVSPSRAWSPRAKQAPRPSFST-RNAGIEAQDRRESLPTSPPWTPGASRPPSSLD 700 P +P SP + P P S +A P P +P AS P S L Sbjct: 591 ----PPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPL- 645 Query: 701 GWVSPGPWEPGRGSS--MSSPPPLPPPPPMSPSWSERSVSPLRPETEARPPSRQLQALLA 758 +P P P + + +P PP PP+ +S + P+ P A PPS Q LA Sbjct: 646 --ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS--ATPPS-QAPPSLA 700 Query: 759 RNIINAARRKSASPRSAGAENPRPFSPP--RAP----PPPPPPPPPPPRMRSPQPARPGS 812 + ASP + + P P +PP AP PP PP PP +P P P Sbjct: 701 APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPL 760 Query: 813 AAVPGAAFAPIPRSPLP----------AGPSSCTSPRSPLPAPPRPF 849 A P P P + LP A P+ T P LP+PP F Sbjct: 761 LAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASF 807 Score = 93.6 bits (231), Expect = 7e-19 Identities = 213/887 (24%), Positives = 298/887 (33%), Gaps = 131/887 (14%) Query: 58 PPAEVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQN 117 PPA+ SP + AS T P A + AT P+ LS+ + Sbjct: 104 PPAKNTSPGPVSSPGRAS-GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARR 162 Query: 118 SSEAQLPSNGTGPASKPSTLCAD--GQPQ-APAEEVRCSTLLIDKVSTPATTTSTFSREA 174 + P + ++ S G P+ AP+ R T P + S+ S + Sbjct: 163 DTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT------EGPRKSVSSASEHS 216 Query: 175 TLIPSS----RPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLA 230 T PS RP A + + + +S+ SG +A TP + H + Sbjct: 217 TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPAR-SGPSARGTPR---APAHPSQP 272 Query: 231 KPPSVVNRTARPFGIQAPG-----GTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPRPQ 285 KP + + RP + P + SP+ G KA P PP PD + P Sbjct: 273 KPKGL--QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKA-RPVPP--PDNAATPL 327 Query: 286 RHIMSRSPMVERRM-----MGQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSY 340 + SP + + P+ + P T P +++T P+ ++PPS Sbjct: 328 PATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPM----QAPPSL 383 Query: 341 SVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQ 400 + P P S P S + S T + P + L + Sbjct: 384 QTIPPIQVPHSLTSPSLQAPPSPLAL---------SSLQATTSLGSPTLQATHSFLTMSP 434 Query: 401 TADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDR-ASPAAAEEVVPEWASCLKSP 459 ++ Q + P + ++ Q AP ASP + P S L SP Sbjct: 435 -------RQTQASLTSPSRPASTPPDSPPLQ---APLSLPASPPLQTSLSPA-VSPLSSP 483 Query: 460 RIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSW 519 P Q LS + + A S + + SS P + P +++ P Sbjct: 484 LTI-----HPLQALSSLASHSPQ--APLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLE 536 Query: 520 KYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKE 579 P+ AP + AS +P TP P P P PP + S+ P Sbjct: 537 NLPSLAPPPLQTAS-APLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAP 595 Query: 580 PAKVSPRAASPAKPSSLDLVPNLPKG----ALPPSPALPRPSRSSPGLYTSPGQDSLQPT 635 PA SP P L P+ ALPP A P P S P L P Sbjct: 596 PALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPP----------LSPL 645 Query: 636 AVSPPYGGDISPVSPSRA-WSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASR 694 A P + V +A +SP + FS S P SP TP + Sbjct: 646 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP----------ASPPVSPSATPPSQA 695 Query: 695 PPS----SLDGWVSPGPWEPGRGSSMSSPPPLPPP-----------PPMSPSWSERSVSP 739 PPS L SP P P S + PP PPP PP SP S + P Sbjct: 696 PPSLAAPPLQVPPSP-PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPP 754 Query: 740 LRP---------ETEARPPSRQLQALLARNIINAARRKSASPRSAGAENP------RPFS 784 R + PP+ + LA+ A + P A P PFS Sbjct: 755 PRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS 814 Query: 785 PPRAPPPPP---PPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRSP 841 P + P P PPP PP + +P P S AP R P P +S + PR Sbjct: 815 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP-RRPPTPGPDTSVSGPRLT 873 Query: 842 L---PAPPRPFLYRRSPTDSDVSLDSEDSGAKS--PGILGYNICPRG 883 L P PP P S T S L S A S + GY+ P G Sbjct: 874 LALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 920 Score = 89.0 bits (219), Expect = 2e-17 Identities = 214/871 (24%), Positives = 301/871 (34%), Gaps = 128/871 (14%) Query: 39 ANGLHLSQNREAQQSSPAPP---PAEVHSPAADVNQNLASPSATLTTPTSNSSHNPPATD 95 A G + R A + P PP P + S A++ + SP+A P + Sbjct: 182 AAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 241 Query: 96 VNQNPPATVVPQSLPLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTL 155 ++ ++ P S P S + P++ + P KP L A PQ + Sbjct: 242 LS----SSATPLSSPARSGPSARGTPRAPAHPSQP--KPKGLQALRPPQVTPPRKDAAPA 295 Query: 156 LIDKVSTPATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAA 215 L S+P T S +A +P PP D ++ L P TL S A Sbjct: 296 LGPLSSSPLATPSPSGTKARPVP---PP--DNAATPL-----PATLPPSPPLATPLPLAP 345 Query: 216 TTPTKVYSEVHFTLAKPPSVVNRTARPFGIQAP-GGTSQMERSPMLERRHFGEKAPAPQP 274 +P+ S TL PP+ A P P ++ P ++ H +P+ Q Sbjct: 346 PSPSAPPSLQ--TLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPH-SLTSPSLQA 402 Query: 275 PSLPDRSPRPQRHIMSRSPMVERR-----MMGQRSPASERRPLGNFTAPPTYTETLSTAP 329 P P Q SP ++ M +++ AS P + PP AP Sbjct: 403 PPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPL--QAP 460 Query: 330 LASWVRSPPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKV 389 L S SPP + L P+ P SS L + A S+A + + + + P Sbjct: 461 L-SLPASPPLQTSLSPAVSPLSSPLTIHPLQALS------SLASHSPQAPLSSLIMPPLE 513 Query: 390 TPNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEAS---------------NFQQEP 434 T + +QT + P A A Q P Sbjct: 514 TQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPP 573 Query: 435 APRDRASPAAAEEVV---PEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRM 491 +P P + P+ L SP +Q P P P L+ + A Sbjct: 574 SPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSP-PLSPLATPPPQAPPXLA------ 626 Query: 492 EKYVIESSSHTPELARCPSPTMSLP-SSWKYPT-NAPGAFRV----ASRSPARTPPASLY 545 P L PSP S P S P+ AP A V A SP +PP Sbjct: 627 ----------LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA- 675 Query: 546 HGYLPENGVLRP--EPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLP 603 P + P P+ PP Q PSL P++ P SP A+ P PS+ P Sbjct: 676 ----PFSPPASPPVSPSATPPSQAPPSL-AAPPLQVPP--SPPASPPMSPSATPPPQAPP 728 Query: 604 KGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPR 663 A PP P P S P ++ + P +PP SP + S SP AK P+ Sbjct: 729 PLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPA-SLPMSPLAKPPPQ 787 Query: 664 PSFSTRNAGIEA-QDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPP-P 721 + ++A S P P++P AS P S L +P P P +++P Sbjct: 788 APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL---ATPPPQAP---PVLAAPLLQ 841 Query: 722 LPPPPPMSPSWSERSVSPLRPETEARPPS---RQLQALLARNIINAARRKSAS----PRS 774 +PP PP SP+ +P RP T S +L LA R +S P Sbjct: 842 VPPSPPASPTLQ----APRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDL 897 Query: 775 AGAENPRPFSPPRAPPPPPPP-------PPPPPRMRSPQPARPGSAAVPGAAFAPIPRSP 827 AG + +P P PPP + + PA P AF P +P Sbjct: 898 AGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP 957 Query: 828 LP----AGPSS----CT-----SPRSPLPAP 845 LP GP S CT P S PAP Sbjct: 958 LPWPPATGPGSADGLCTIYETEGPESATPAP 988 Score = 78.6 bits (192), Expect = 2e-14 Identities = 199/850 (23%), Positives = 273/850 (32%), Gaps = 177/850 (20%) Query: 48 REAQQSSPAPPPAEVHSPAADVNQNLASPSATLTTPT---SNSSHNPPATDVNQNPPATV 104 R Q + P A P + SPS T P N++ PAT P AT Sbjct: 281 RPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATP 340 Query: 105 VPQSLPLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPA 164 +P + P S S LPS P S+ QAP S I + P Sbjct: 341 LPLAPPSPSAPP--SLQTLPSPPATPPSQAPPSMTTPPMQAPP-----SLQTIPPIQVPH 393 Query: 165 TTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSE 224 + TS PS + P S SSL Q T + S + + +P + ++ Sbjct: 394 SLTS---------PSLQAPPSPLALSSL----QATTSLGSPTLQATHSFLTMSPRQ--TQ 438 Query: 225 VHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQP---------P 275 T P+ + P +QAP + SP L+ +P P Sbjct: 439 ASLTSPSRPASTPPDSPP--LQAP---LSLPASPPLQTSLSPAVSPLSSPLTIHPLQALS 493 Query: 276 SLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETL-STAPLASWV 334 SL SP+ + P+ + + +P S + P + T PP E L S AP Sbjct: 494 SLASHSPQAPLSSLIMPPLETQSSL---APPSLQTPPASLTTPPL--ENLPSLAP----- 543 Query: 335 RSPPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPD 394 PP + P + P HL+ PA P TP P+ Sbjct: 544 --PPLQTASAPLTTP---HLETPPCPAP----------------CPLQAPPSPLTTPPPE 582 Query: 395 LLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWAS 454 + T + P AL + P A+P P+ Sbjct: 583 TPSSIATPPP-------------QAPPALASPPLQGLPSPPLSPLATPP------PQAPP 623 Query: 455 CLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMS 514 L P +QA P P + LS + + + + +++++ P PSP + Sbjct: 624 XLALPPLQAPPSPPASPPLSPLATPSPQA----PNALAVHLLQAPFSPP-----PSPPVQ 674 Query: 515 LP----------SSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPP 564 P S P+ AP + +PPAS P P PP Sbjct: 675 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 734 Query: 565 YQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLY 624 Q+ PS SP P+ P P + VP P +LP SP P ++ P L Sbjct: 735 LQVPPSP-PASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALA 793 Query: 625 TSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPT 684 T P Q P A P +P SPS + P P A Q +P Sbjct: 794 TPPLQALPSPPASFPGQ----APFSPSASLPMSPLATPPPQAPPVLAAPLLQ-----VPP 844 Query: 685 SPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSP-------PPLPPPPPMSPSWS---- 733 SPP +P P P PG +S+S P P PPPP SPS + Sbjct: 845 SPPASPTLQAPRR---------PPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 895 Query: 734 ----ERSVSPLRPE-------------TEARPPSRQLQALLARNIINAARRKSASPRSA- 775 S + PE + PP +L A AA + +P A Sbjct: 896 DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHP-----AAWSRGPAPPLAF 950 Query: 776 -GAEN-PRPFSPPRAPP-------------PPPPPPPPPPRMRSPQPARPGSAAVPGAAF 820 GA P P+ P P P P P P P G A GA Sbjct: 951 RGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGA 1010 Query: 821 APIPRSPLPA 830 RSP A Sbjct: 1011 GASSRSPKQA 1020 Score = 77.8 bits (190), Expect = 4e-14 Identities = 112/429 (26%), Positives = 155/429 (36%), Gaps = 44/429 (10%) Query: 437 RDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVI 496 RD+A AA A L +PR P+P P + GA R+ E+ Sbjct: 5 RDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGG 64 Query: 497 ESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRS-PARTPPASLYHGYLPENGVL 555 + PE A PT S +S + P + P A R+ PA+ +G Sbjct: 65 IGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTT 124 Query: 556 RPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPR 615 RP P Q ++ V + A +P+ ++ + + D P PSPA+ R Sbjct: 125 RPGPLGQKGLRISAEETV---ARGKATEAPKRSALSAGARRDTSGPTPG---TPSPAMAR 178 Query: 616 PSRSSPGLYTSPGQDSLQPTA-VSPPYGG---DISPVSPSRAWSPRAKQAPRPSFSTRNA 671 SR++ T G P+A PP G +S S P RPS Sbjct: 179 RSRAAG---TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPS---AGG 232 Query: 672 GIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPG-PWEP-GRGSSMSSPPPLPPP---- 725 G++ R ++ P + A PS+ +P P +P +G PP + PP Sbjct: 233 GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA 292 Query: 726 -PPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFS 784 P + P S +P T+ARP A A + P S P P + Sbjct: 293 APALGPLSSSPLATPSPSGTKARPVPPPDNA--------ATPLPATLPPSPPLATPLPLA 344 Query: 785 PPRAPPPP-----PPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPR 839 PP PP P PP PP P P A P P P+ P S TSP Sbjct: 345 PPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIP----PIQV-PHSLTSP- 398 Query: 840 SPLPAPPRP 848 L APP P Sbjct: 399 -SLQAPPSP 406 Score = 47.4 bits (111), Expect = 6e-05 Identities = 41/122 (33%), Positives = 52/122 (42%), Gaps = 13/122 (10%) Query: 765 ARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPA---RPGSAAVPGAAFA 821 A ++ + R+ G PRP PR PPPP P R+ A +P + G A Sbjct: 12 AAARTPAARAPGLLTPRPPGSPR---PPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68 Query: 822 PIPRSPLPAGP--SSCTSPRSPLPAPPRPFLYRRSP-----TDSDVSLDSEDSGAKSPGI 874 IP S AGP S+ TS R+P PP R+P + VS SG PG Sbjct: 69 TIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGP 128 Query: 875 LG 876 LG Sbjct: 129 LG 130 >gi|193083191 synaptopodin 2 isoform c [Homo sapiens] Length = 1109 Score = 101 bits (252), Expect = 3e-21 Identities = 131/494 (26%), Positives = 193/494 (39%), Gaps = 139/494 (28%) Query: 311 PLGNFTAPPTYTETLS---------TAPLASWVRSPP-------SYSVLYPSSDPKSSHL 354 P+ +F APP Y+ ++P+A + PP S Y SS+ +S Sbjct: 612 PIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRD 671 Query: 355 KGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEV 414 + +VPA +TGIL+E+ RR + K MFTF E PKV+PNP+LL L+Q ++ KR G+ Sbjct: 672 ERISVPAKRTGILQEAK-RRSTTKPMFTFKE-PKVSPNPELLSLLQNSEGKRGTGAGGDS 729 Query: 415 GVEEEPFALGAEASNFQQEPAPRDRASPAAAEE-------------VVPEWASCLKSPRI 461 G EE+ +LGAEA NF Q + + + P A + V P W+ + + Sbjct: 730 GPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQP 789 Query: 462 QAKPKPKPNQNLSEASGKGAELY---ARRQSRME--------KYVIESSSHTPELARCPS 510 A P P++ +S K A+ AR S + + + S ++TP+ Sbjct: 790 PAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPK------ 843 Query: 511 PTMSLPSSWKYPTNAPG------------------------------------AFRVASR 534 PT+S P+ A G A R S Sbjct: 844 PTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSP 903 Query: 535 SPA-----------RTPPASLY---HGYLPENGVLRPEPTKQPP---------------- 564 +P+ R PP Y H L+ +P+ P Sbjct: 904 TPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALD 963 Query: 565 ------YQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPA------ 612 YQL SLF P + P+ +S S+L + K ALPP P Sbjct: 964 VMKHQPYQLNASLFTFQP-PDAKDGLPQKSSVKVNSALAM-----KQALPPRPVNAASPT 1017 Query: 613 -LPRPSRSSPGLYTSPGQ---DSLQPTAVSP-PYGGDISPVSPSRAWSPRAKQAPRPSFS 667 + S S YTSP ++ P + SP P G SP S + S APRP FS Sbjct: 1018 NVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFV--APRPKFS 1075 Query: 668 TRNAGIEAQDRRES 681 + +G+ Q + +S Sbjct: 1076 AKKSGVTIQVKCKS 1089 Score = 49.7 bits (117), Expect = 1e-05 Identities = 100/476 (21%), Positives = 162/476 (34%), Gaps = 91/476 (19%) Query: 473 LSEASGKGAELYARRQSRMEKYVIESSSH----TPELARCPSPTMSLPSSWKYPTNAPGA 528 L + +GKGA ++A+R+ RM++ + TP + + T L ++ Y + Sbjct: 484 LPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKEEES 543 Query: 529 FRV----------ASRSPARTPPASLYHG---------YLPENGVLRPEP--TKQPPYQL 567 R S P + + G +P N +P P QP Sbjct: 544 VRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPATPF 603 Query: 568 RPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSR-SSPGLYTS 626 P+ + SPI + P +A P + + P P P+P+ S P Y S Sbjct: 604 SPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDS 663 Query: 627 PGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSP 686 + + + +S P + + +P F+ + + SL + Sbjct: 664 SERIASRDERISVP------AKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNS 717 Query: 687 PWT--PGASRPPSSLDGWVSPGP----WEPGRGSSMSSPPPLPPPP-----------PMS 729 GA + ++S G + + +PPP+ P P P+S Sbjct: 718 EGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVS 777 Query: 730 PSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAEN-PRPFSPPRA 788 P WS V+P +P A P S + + + I A+ R A N PF P+A Sbjct: 778 PVWSP-GVAPTQP--PAFPTSNPSKGTVVSS-IKIAQPSYPPARPASTLNVAGPFKGPQA 833 Query: 789 PPP----PPPPPPPPPRMRSPQPARPG-SAAVPG-------------------------- 817 P P P + + QP G S +PG Sbjct: 834 AVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTV 893 Query: 818 ---AAFAPIPRSPLPAGPSSCTSPRSPLPAPPRPFLYRRSPTDSDVSLDSEDSGAK 870 AA A P LPA ++ R+P P P SP+ +L S+ S A+ Sbjct: 894 QAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPI---HSPSYPLAALKSQPSAAQ 946 >gi|193083185 synaptopodin 2 isoform b [Homo sapiens] Length = 1093 Score = 101 bits (251), Expect = 4e-21 Identities = 130/489 (26%), Positives = 190/489 (38%), Gaps = 139/489 (28%) Query: 311 PLGNFTAPPTYTETLS---------TAPLASWVRSPP-------SYSVLYPSSDPKSSHL 354 P+ +F APP Y+ ++P+A + PP S Y SS+ +S Sbjct: 612 PIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRD 671 Query: 355 KGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEV 414 + +VPA +TGIL+E+ RR + K MFTF E PKV+PNP+LL L+Q ++ KR G+ Sbjct: 672 ERISVPAKRTGILQEAK-RRSTTKPMFTFKE-PKVSPNPELLSLLQNSEGKRGTGAGGDS 729 Query: 415 GVEEEPFALGAEASNFQQEPAPRDRASPAAAEE-------------VVPEWASCLKSPRI 461 G EE+ +LGAEA NF Q + + + P A + V P W+ + + Sbjct: 730 GPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVSPVWSPGVAPTQP 789 Query: 462 QAKPKPKPNQNLSEASGKGAELY---ARRQSRME--------KYVIESSSHTPELARCPS 510 A P P++ +S K A+ AR S + + + S ++TP+ Sbjct: 790 PAFPTSNPSKGTVVSSIKIAQPSYPPARPASTLNVAGPFKGPQAAVASQNYTPK------ 843 Query: 511 PTMSLPSSWKYPTNAPG------------------------------------AFRVASR 534 PT+S P+ A G A R S Sbjct: 844 PTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSP 903 Query: 535 SPA-----------RTPPASLY---HGYLPENGVLRPEPTKQPP---------------- 564 +P+ R PP Y H L+ +P+ P Sbjct: 904 TPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKPLNALD 963 Query: 565 ------YQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPA------ 612 YQL SLF P + P+ +S S+L + K ALPP P Sbjct: 964 VMKHQPYQLNASLFTFQP-PDAKDGLPQKSSVKVNSALAM-----KQALPPRPVNAASPT 1017 Query: 613 -LPRPSRSSPGLYTSPGQ---DSLQPTAVSP-PYGGDISPVSPSRAWSPRAKQAPRPSFS 667 + S S YTSP ++ P + SP P G SP S + S APRP FS Sbjct: 1018 NVQASSVYSVPAYTSPPSFFAEASSPVSASPVPVGIPTSPKQESASSSYFV--APRPKFS 1075 Query: 668 TRNAGIEAQ 676 + +G+ Q Sbjct: 1076 AKKSGVTIQ 1084 Score = 49.7 bits (117), Expect = 1e-05 Identities = 100/476 (21%), Positives = 162/476 (34%), Gaps = 91/476 (19%) Query: 473 LSEASGKGAELYARRQSRMEKYVIESSSH----TPELARCPSPTMSLPSSWKYPTNAPGA 528 L + +GKGA ++A+R+ RM++ + TP + + T L ++ Y + Sbjct: 484 LPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLRTTTSYQRKEEES 543 Query: 529 FRV----------ASRSPARTPPASLYHG---------YLPENGVLRPEP--TKQPPYQL 567 R S P + + G +P N +P P QP Sbjct: 544 VRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPATPF 603 Query: 568 RPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSR-SSPGLYTS 626 P+ + SPI + P +A P + + P P P+P+ S P Y S Sbjct: 604 SPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDS 663 Query: 627 PGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSP 686 + + + +S P + + +P F+ + + SL + Sbjct: 664 SERIASRDERISVP------AKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNS 717 Query: 687 PWT--PGASRPPSSLDGWVSPGP----WEPGRGSSMSSPPPLPPPP-----------PMS 729 GA + ++S G + + +PPP+ P P P+S Sbjct: 718 EGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKSSSSQPVTPVS 777 Query: 730 PSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAEN-PRPFSPPRA 788 P WS V+P +P A P S + + + I A+ R A N PF P+A Sbjct: 778 PVWSP-GVAPTQP--PAFPTSNPSKGTVVSS-IKIAQPSYPPARPASTLNVAGPFKGPQA 833 Query: 789 PPP----PPPPPPPPPRMRSPQPARPG-SAAVPG-------------------------- 817 P P P + + QP G S +PG Sbjct: 834 AVASQNYTPKPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTV 893 Query: 818 ---AAFAPIPRSPLPAGPSSCTSPRSPLPAPPRPFLYRRSPTDSDVSLDSEDSGAK 870 AA A P LPA ++ R+P P P SP+ +L S+ S A+ Sbjct: 894 QAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPI---HSPSYPLAALKSQPSAAQ 946 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 99.0 bits (245), Expect = 2e-20 Identities = 174/686 (25%), Positives = 240/686 (34%), Gaps = 101/686 (14%) Query: 231 KPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHF--GEKAPAPQPPSLPDRSP-RPQRH 287 +PP V P ++ G + R P+ ER G P P + P RS R+ Sbjct: 34 RPPPPVT----PAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRN 89 Query: 288 IMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLASW---VRSPPSYSVLY 344 SR P R G+R+P ++ G ++P + T PL + + + + Sbjct: 90 PASRPPASGR---GERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGK 146 Query: 345 PSSDPKSSHLKGQA---VPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQT 401 + PK S L A G +MARR ++ T V P+ P P T Sbjct: 147 ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS--RAAGTEVGLPR--PAPSARPRPPT 202 Query: 402 ADEKRRQRDQGEVGVEEEPFALGAE--ASNFQQEPAPRDRASPA----AAEEVVPEWASC 455 ++ E E A A Q PA R +S A + P Sbjct: 203 EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT 262 Query: 456 LKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSL 515 ++P ++PKPK Q L R + P L S ++ Sbjct: 263 PRAPAHPSQPKPKGLQAL----------------RPPQVTPPRKDAAPALGPLSSSPLAT 306 Query: 516 PS-SWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVL 574 PS S + AP PA +SL + P P+ P Q PS Sbjct: 307 PSPSAALQSQAPPTL------PATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPS---- 356 Query: 575 SPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQP 634 P P++ + SP ++ +P+ P L P P+ + P L P Sbjct: 357 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP------- 409 Query: 635 TAVSPPYGGDISPVSPSRAWSPRAKQA---PRPSFSTRNAGIEAQDRRESLPTSPPWTPG 691 SPP +SP++ +P A P + ++A S P SPP +P Sbjct: 410 ---SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF---SPPASPPVSPS 463 Query: 692 ASRP---PSSLDG---WVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETE 745 A+ P P SL V P P S ++PPP PPP +P P P Sbjct: 464 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL 523 Query: 746 ARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPP---PPPPPPPRM 802 A PP LQAL SP A PFSP + P P PPP PP + Sbjct: 524 ATPP---LQAL-------------PSP-PASFPGQAPFSPSASLPMSPLATPPPQAPPVL 566 Query: 803 RSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRSPL---PAPPRPFLYRRSPTDSD 859 +P P S AP R P P +S + PR L P PP P S T S Sbjct: 567 AAPLLQVPPSPPASPTLQAP-RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG 625 Query: 860 VSLDSEDSGAKS--PGILGYNICPRG 883 L S A S + GY+ P G Sbjct: 626 PDLAGHSSSATSTPEELRGYDSGPEG 651 Score = 82.8 bits (203), Expect = 1e-15 Identities = 122/479 (25%), Positives = 174/479 (36%), Gaps = 80/479 (16%) Query: 437 RDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVI 496 RD+A AA A L +PR P+P P + GA R+ E+ Sbjct: 5 RDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGG 64 Query: 497 ESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRS-PARTPPASLYHGYLPENGVL 555 + PE A PT S +S + P + P A R+ PA+ +G Sbjct: 65 IGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTT 124 Query: 556 RPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGAL-------- 607 RP P Q ++ V A ++ A+ + P P A+ Sbjct: 125 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184 Query: 608 -------PPSPALPRPSRSSPGLYTSPGQD--SLQPTAVS---PPYGGDI---------- 645 P A PRP P S + + +P+ + P GG + Sbjct: 185 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 244 Query: 646 --SPVSPSRAWSPRAKQAPR----PSFSTRNAGIEA-------QDRRESLP------TSP 686 +P+S P A+ PR PS + G++A R+++ P +SP Sbjct: 245 SATPLSSPARSGPSARGTPRAPAHPS-QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 303 Query: 687 PWTPGASRPPSSLDGWVSPG-PWEPGRGS---SMSSPPPLPPPPPMSPSWSERSVSPLRP 742 TP P ++L P P P S +++P PL PP P +P S+ L P Sbjct: 304 LATPS---PSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPP----SLQTL-P 355 Query: 743 ETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSPP-------RAPPPPPPP 795 A PPS Q L + A SP + P P +PP +APP PP Sbjct: 356 SPPATPPS-QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS 414 Query: 796 PPPPPRMRSPQPARPGSAAVP--GAAFAPIPRSPL------PAGPSSCTSPRSPLPAPP 846 PP P + +P P P + AV A F+P P P+ PA P S P APP Sbjct: 415 PPLSP-LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 472 Score = 79.7 bits (195), Expect = 1e-14 Identities = 180/740 (24%), Positives = 246/740 (33%), Gaps = 139/740 (18%) Query: 163 PATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPT--- 219 P + T SR P+SRPPAS + P GRA+ TT Sbjct: 79 PTRSAGTSSRN----PASRPPASGRGERA-----PPAKNTSPGPVSSPGRASGTTRPGPL 129 Query: 220 -----KVYSEVHFTLAKPPSVVNRTARPFGIQAP-GGTSQMERSPMLERRHFGEKAPAPQ 273 ++ +E K R+A G + G + SP + RR Sbjct: 130 GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189 Query: 274 PPSLPDRSPRPQRHIMSRS-PMVERRMMGQRSPASERRPL--GNFTAPPTYTETLSTAPL 330 P P PRP +S + SPA+ RRP G P + + + S PL Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249 Query: 331 ASWVRSPPSY-----SVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVE 385 +S RS PS + +PS PK L+ P + + R+ + ++ Sbjct: 250 SSPARSGPSARGTPRAPAHPSQ-PKPKGLQALRPP-------QVTPPRKDAAPALGPLSS 301 Query: 386 KPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEE---PFALGAEASNFQQEPAPRDRASP 442 P TP+P Q + + P A + ++ + P A+P Sbjct: 302 SPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATP 361 Query: 443 AAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHT 502 + + + L SP +QA P+ LS + + + Sbjct: 362 PS------QATTSLGSPTLQATHSFLPSPPLSPLATPPPQA-------------PPALAL 402 Query: 503 PELARCPSPTMSLP-SSWKYPT-NAPGAFRV----ASRSPARTPPASLYHGYLPENGVLR 556 P L PSP S P S P+ AP A V A SP +PP P + Sbjct: 403 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA-----PFSPPAS 457 Query: 557 P--EPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALP 614 P P+ PP Q PSL P++ P SP A+ P PS+ P A PP Sbjct: 458 PPVSPSATPPSQAPPSL-AAPPLQVPP--SPPASPPMSPSATPPPQAPPPLAAPPLQLAK 514 Query: 615 RPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIE 674 P ++ P L T P Q P A P +P SPS + P P A Sbjct: 515 PPPQAPPALATPPLQALPSPPASFPGQ----APFSPSASLPMSPLATPPPQAPPVLAAPL 570 Query: 675 AQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSP-------PPLPPPPP 727 Q +P SPP +P P P PG +S+S P P PPPP Sbjct: 571 LQ-----VPPSPPASPTLQAPRR---------PPTPGPDTSVSGPRLTLALAPGPPPPPS 616 Query: 728 MSPSWS--------ERSVSPLRPE-------------TEARPPSRQLQALLARNIINAAR 766 SPS + S + PE + PP +L A AA Sbjct: 617 RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHP-----AAW 671 Query: 767 RKSASPRSA--GAEN-PRPFSPPRAPP-------------PPPPPPPPPPRMRSPQPARP 810 + +P A GA P P+ P P P P P P P Sbjct: 672 SRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTS 731 Query: 811 GSAAVPGAAFAPIPRSPLPA 830 G A GA RSP A Sbjct: 732 GGKAAAGAGAGASSRSPKQA 751 Score = 58.2 bits (139), Expect = 3e-08 Identities = 75/289 (25%), Positives = 104/289 (35%), Gaps = 37/289 (12%) Query: 578 KEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAV 637 ++ AK A +PA + L P P PP P P R G + G+ L A Sbjct: 5 RDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVL-GAAGAVGRKPLAERAG 63 Query: 638 SPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIE--AQDRRESLPTSPPWTPGASRP 695 GG P S +PRA S+RN A R E P + +PG Sbjct: 64 G--IGGATIPES-----APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSS 116 Query: 696 PSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEARPPSRQLQA 755 P G PGP +G +S+ + + R +T P A Sbjct: 117 PGRASGTTRPGPLGQ-KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPA 175 Query: 756 LLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPP-----------PPPPPPPRMRS 804 + ARR A+ G P P + PR P P P P R Sbjct: 176 M--------ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 227 Query: 805 PQPA----RPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRSPL-PAPPRP 848 P RP S ++ +A P+ SP +GPS+ +PR+P P+ P+P Sbjct: 228 PSAGGGLQRPASRSLSSSA-TPL-SSPARSGPSARGTPRAPAHPSQPKP 274 Score = 47.4 bits (111), Expect = 6e-05 Identities = 41/122 (33%), Positives = 52/122 (42%), Gaps = 13/122 (10%) Query: 765 ARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPA---RPGSAAVPGAAFA 821 A ++ + R+ G PRP PR PPPP P R+ A +P + G A Sbjct: 12 AAARTPAARAPGLLTPRPPGSPR---PPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68 Query: 822 PIPRSPLPAGP--SSCTSPRSPLPAPPRPFLYRRSP-----TDSDVSLDSEDSGAKSPGI 874 IP S AGP S+ TS R+P PP R+P + VS SG PG Sbjct: 69 TIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGP 128 Query: 875 LG 876 LG Sbjct: 129 LG 130 Score = 40.0 bits (92), Expect = 0.010 Identities = 73/308 (23%), Positives = 107/308 (34%), Gaps = 37/308 (12%) Query: 50 AQQSSPAPP--PAEVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQ 107 A S APP PA HS + + LA+P L P+ ++ PP+ +PPAT Q Sbjct: 311 AALQSQAPPTLPATPHS--SSLTCQLATP-LPLAPPSPSA---PPSLQTLPSPPATPPSQ 364 Query: 108 -SLPLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATT 166 + L S ++ + LPS P + P PQAP L + + P + Sbjct: 365 ATTSLGSPTLQATHSFLPSPPLSPLATP-------PPQAP------PALALPPLQAPPSP 411 Query: 167 TSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVH 226 ++ PS + P + + P + V A + S+ Sbjct: 412 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 471 Query: 227 FTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQ-PPSLP----DRS 281 +LA PP V + +P T + P L P PQ PP+L Sbjct: 472 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQAL 531 Query: 282 PRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYS 341 P P ++P SP S P+ PP + APL SPP+ Sbjct: 532 PSPPASFPGQAPF---------SP-SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP 581 Query: 342 VLYPSSDP 349 L P Sbjct: 582 TLQAPRRP 589 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 95.1 bits (235), Expect = 3e-19 Identities = 123/402 (30%), Positives = 145/402 (36%), Gaps = 80/402 (19%) Query: 498 SSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVA-----------SRSPARTPPASLYH 546 + HTP +R S P PT+ P A VA S P P Sbjct: 362 AEQHTPVCSR-----FSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEA 416 Query: 547 GYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKP----SSLDLVPN- 601 L + GV + EP + P L + +L P +E P SP P S L P Sbjct: 417 KPLGKAGV-QLEPQLEAP--LNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEE 473 Query: 602 LPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGG-DISPVSPSRAWSP---- 656 LP LP + L RP SP L P + L P S P+ + SP+SP P Sbjct: 474 LPASPLPEALHLSRPLEESP-LSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPAL 532 Query: 657 RAKQAPRPSFSTRNAGIEAQDRR---ESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRG 713 +P P S + E E LPTSPP P ASR +SP P E Sbjct: 533 ETPLSPPPEASPLSPPFEESPLSPPPEELPTSPP--PEASR--------LSPPPEE---- 578 Query: 714 SSMSSPP---PLPPPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSA 770 S MS PP P+ PPP S + SPL P E P S Sbjct: 579 SPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLS-------------------- 618 Query: 771 SPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPA 830 P A +P P P +PPP P PPP + P S P P SPL Sbjct: 619 PPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSP-----PPEESPLSP 673 Query: 831 GPSSCTSPRSPLPAPPRPFLYRRSPTDSDVSLDSEDSGAKSP 872 P SP SP PP P DS S EDS A P Sbjct: 674 PPEE--SPTSP---PPEASRLSPPPEDSPTSPPPEDSPASPP 710 Score = 92.4 bits (228), Expect = 2e-18 Identities = 201/856 (23%), Positives = 294/856 (34%), Gaps = 213/856 (24%) Query: 22 EEVPLVVYLKENAALLTANGLHLSQNREAQQSSPAPPPAEVHSPAADVNQNLASPSATLT 81 EE+PL+ +E+ LS E +SP P + + P ++ + + L+ Sbjct: 436 EEMPLLPPPEESP---------LSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLS 486 Query: 82 TPTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQNSSEAQLPSNGTGPASKPSTLCADG 141 P S +PP + +PP P+S P S ++++ P S P + Sbjct: 487 RPLEESPLSPPPEESPLSPP----PESSPFSPLEES------------PLSPP-----EE 525 Query: 142 QPQAPAEEVRCSTLLIDKVSTPATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTL 201 P +PA E S +P S S +P+S PP + +S P Sbjct: 526 SPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSP------PPEES 579 Query: 202 VVSADQEMSGRAAATTPTKVYSEVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLE 261 +S E S + ++++ + PP + P S++ P Sbjct: 580 PMSPPPEESPMSPPPEASRLFPPFEESPLSPP------PEESPLSPPPEASRLSPPP--- 630 Query: 262 RRHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLG-----NFT 316 E +P PP SP P+ +S P+V R SP E PL + T Sbjct: 631 -----EDSPMSPPPEESPMSPPPEVSRLSPLPVVSR-----LSPPPEESPLSPPPEESPT 680 Query: 317 APPTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSSHLKGQAVPASKTGIL----EESMA 372 +PP LS P S PP S P+S P L ++P ++ +L E + Sbjct: 681 SPPPEASRLSPPPEDSPTSPPPEDS---PASPPPEDSL--MSLPLEESPLLPLPEEPQLC 735 Query: 373 RRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGE---VGVEEEPFALGAEASN 429 R + E+P ++P P+ L A+E E V EEP L +A Sbjct: 736 PRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPH-LSPQAEG 794 Query: 430 FQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQS 489 P P + EE P + + P + P+P ++ + L R Sbjct: 795 PHLSPQPEELHLSPQTEE--PHLSPVPEEPCL----SPQPEESHLSPQSEEPCLSPRP-- 846 Query: 490 RMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYL 549 E S +PEL + P L + P PG P PP Sbjct: 847 -------EESHLSPELEKPP-----LSPRPEKPPEEPGQCPAPEELPLFPPPGE------ 888 Query: 550 PENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPP 609 P L EP P + LSP+ E +SP P+L +PP Sbjct: 889 PSLSPLLGEPALSEPGEP-----PLSPLPEELPLSPSGE-----------PSLSPQLMPP 932 Query: 610 SPALPRPSRSSPGLYTSPGQDSLQPTAVSP------PYG--GDISPVSPSRAWSPRAKQA 661 P LP P SP + P A+SP P+G GD P SP A Sbjct: 933 DP-LPPP--------LSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAA-------- 975 Query: 662 PRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPPP 721 P T P SPP + P EP PP Sbjct: 976 --PILET--------------PISPPPEANCTDP-------------EP-------VPPM 999 Query: 722 LPPPPPMSPSWSERSVSPLRP-ETEARPPSRQLQALLARNIINAARRKSASPRSAGAENP 780 + PP P SP V P P E PP Q LL +++ P+++ P Sbjct: 1000 ILPPSPGSP------VGPASPILMEPLPP--QCSPLLQHSLV---------PQNS---PP 1039 Query: 781 RPFSPPRAPPPPPPPPPPPPR------------MRSPQPARPGSAAVPGAAFAPIPRSPL 828 SPP P P P P + M + + + P A+ +A +P+P Sbjct: 1040 SQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPS--- 1096 Query: 829 PAGPSSCTSPRSPLPA 844 P G SC +P SP PA Sbjct: 1097 PMGDLSCPAP-SPAPA 1111 Score = 87.0 bits (214), Expect = 7e-17 Identities = 154/630 (24%), Positives = 211/630 (33%), Gaps = 103/630 (16%) Query: 248 PGGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPAS 307 P G + ++ P LE E+ P PP SP P+ S P R + Sbjct: 418 PLGKAGVQLEPQLEAP-LNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPA 476 Query: 308 ERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSSD-PKSSHLKGQAVPASKTGI 366 P + P LS P S + PP S P + P S + PA +T + Sbjct: 477 SPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPL 536 Query: 367 LEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGV----EEEPFA 422 A S F E P ++P P+ L + R E + EE P + Sbjct: 537 SPPPEASPLSPP----FEESP-LSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMS 591 Query: 423 LGAEASN----FQQEP-APRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEAS 477 EAS F++ P +P SP + P AS L P + P P E S Sbjct: 592 PPPEASRLFPPFEESPLSPPPEESPLSP----PPEASRLSPPPEDSPMSPPP-----EES 642 Query: 478 GKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPA 537 R S + V+ S PE + P P+S P A SP Sbjct: 643 PMSPPPEVSRLSPLP--VVSRLSPPPEESPLSPPPEESPTS--PPPEASRLSPPPEDSPT 698 Query: 538 RTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASP---AKPS 594 PP PE+ ++ P ++ P P L P E +SPR P +P Sbjct: 699 SPPPEDSPASPPPEDSLMSL-PLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPE 757 Query: 595 SLDLVPNLPKGALPPSPALP-----------RPSRSSPGLYTSPGQDSLQPTAVSP---- 639 L P + L P P P P P L P + L P P Sbjct: 758 EPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSP 817 Query: 640 -PYGGDISPVSPSRAWSPRAKQ---APRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRP 695 P +SP SP++++ +PRP S + +E PP +P +P Sbjct: 818 VPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELE----------KPPLSPRPEKP 867 Query: 696 PSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEARPPSRQLQA 755 P EPG+ + P PPP E S+SPL E P + Sbjct: 868 PE-----------EPGQCPAPEELPLFPPP-------GEPSLSPLLGEPALSEPGEPPLS 909 Query: 756 LLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPARPGSAAV 815 L + P S E P P+ PP P PPP P + + P Sbjct: 910 PLPEEL----------PLSPSGE---PSLSPQLMPPDPLPPPLSPIITAAAPP------- 949 Query: 816 PGAAFAPIPRSPLPAGPSSCTSPRSPLPAP 845 A +P+ P G + P SPL AP Sbjct: 950 ---ALSPLGELEYPFGAKGDSDPESPLAAP 976 Score = 62.4 bits (150), Expect = 2e-09 Identities = 95/341 (27%), Positives = 132/341 (38%), Gaps = 68/341 (19%) Query: 556 RPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLV-PNLPKGA---LPPSP 611 +P PP P++F+ SP PA +S A KP + + P+ P LPP Sbjct: 2109 QPGALGSPPPAAAPTIFIGSPTT-PAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQV 2167 Query: 612 ALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNA 671 PS+ GL + + PTA P Y P PS +P Q P S+R Sbjct: 2168 PAQVPSQDPFGLAPAYPLEPRFPTA-PPTY-----PPYPSPTGAPA--QPPMLGASSRPG 2219 Query: 672 GIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPG---------PWEPGRGSSMSSPPPL 722 + + T+PP TP PS+ D ++ P P PG G +S P L Sbjct: 2220 AGQPGE----FHTTPPGTP--RHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLL 2273 Query: 723 PPPPPMSPSWSERSVSPLRPETEARPPSRQ------LQALLARNIINAARRKSA----SP 772 PPP S +++ + E A PS + + + + K+ +P Sbjct: 2274 SPPPFGE---SRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAP 2330 Query: 773 RSAGAENPRPFSP-----PRAPPP-----PPPPPPP--------------PPRMRSPQPA 808 + A P SP P+ PPP P PP P PP PQP Sbjct: 2331 LTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPP 2390 Query: 809 RPGSA-AVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAPPRP 848 P S A+P + P S +PA P S +S +SPL PRP Sbjct: 2391 PPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPL--TPRP 2429 Score = 59.7 bits (143), Expect = 1e-08 Identities = 179/793 (22%), Positives = 257/793 (32%), Gaps = 142/793 (17%) Query: 22 EEVPLVVYLKENAALLTANGLHLSQNREAQQSSPAPPPAEVHSPAADVNQNLASPSATLT 81 E PL +E+ L S EA + SP P + + P + + ++ L Sbjct: 541 EASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLF 600 Query: 82 TPTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQNSSEAQLPSNGTGPASKPSTLCADG 141 P S +PP + +PP S P + + P + S+ S L Sbjct: 601 PPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVS 660 Query: 142 QPQAPAEEVRCSTLLIDKVSTPATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTL 201 + P EE S + ++P S S P+S PP S P Sbjct: 661 RLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASP------PPEDS 714 Query: 202 VVSADQEMSGRAAATTPTKVYSEVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLE 261 ++S E S L + P + R+ P SP E Sbjct: 715 LMSLPLEESPL--------------LPLPEEPQLCPRSEGP------------HLSPRPE 748 Query: 262 RRHFGEKAPAPQPPSL------PDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNF 315 H +P P+ P L P SP+P+ + P P +P Sbjct: 749 EPHL---SPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELH 805 Query: 316 TAPPTYTETLSTAPLASWVRSPPSYSVLYPSSD-------PKSSHLKGQAVPASKTGILE 368 +P T LS P + P S L P S+ P+ SHL + LE Sbjct: 806 LSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPE---------LE 856 Query: 369 ESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEE--EPFALGAE 426 + K E+P P P+ L L E GE + E EP L Sbjct: 857 KPPLSPRPEKP----PEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEP-PLSPL 911 Query: 427 ASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYAR 486 P+ SP + + P+ SP I A P + GA+ + Sbjct: 912 PEELPLSPSGEPSLSP---QLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSD 968 Query: 487 RQSRMEKYVIESSSHTPELARC----PSPTMSLPSSWKYPTNAPGAFRVASRSPARTPPA 542 +S + ++E+ P A C P P M LP S P + P +P Sbjct: 969 PESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSP-- 1026 Query: 543 SLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPI--------------KEPAKVSPRAA 588 L H +P+N P PP LSPI E KVS Sbjct: 1027 LLQHSLVPQNS---PPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPEC 1083 Query: 589 SPAKPSSLDLVPNLPKGAL-----PPSPAL-----------PRPSRSSPGLYTSPGQ--D 630 +PS+ +P+ P G L P+PAL P +PG PGQ Sbjct: 1084 PALEPSATSPLPS-PMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPG 1142 Query: 631 SL------QPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPT 684 SL P + P +++PV+P + P KQ T G +++ E Sbjct: 1143 SLASELKGSPVLLDPE---ELAPVTPMEVY-PECKQ-------TAGQGSPCEEQEE---- 1187 Query: 685 SPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPP---PL--PPPPPMSPSWS-----E 734 P P A PP+ + + +G + +S P PL P P S S Sbjct: 1188 --PRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVS 1245 Query: 735 RSVSPLRPETEAR 747 VSP R E R Sbjct: 1246 TDVSPARDEGSLR 1258 Score = 59.3 bits (142), Expect = 2e-08 Identities = 96/350 (27%), Positives = 125/350 (35%), Gaps = 65/350 (18%) Query: 563 PPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPS-----PALPRPS 617 P Y L P F +P P SP A PA+P L + P P P PR Sbjct: 2181 PAYPLEPR-FPTAPPTYPPYPSPTGA-PAQPPMLG-ASSRPGAGQPGEFHTTPPGTPRHQ 2237 Query: 618 RSSPGLYTSPGQDSLQPTAV--SPPYGGDIS--------PVSPSRAWSPRAKQ---APRP 664 S+P + P SL AV SP GG + P SR K+ A P Sbjct: 2238 PSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSP 2297 Query: 665 SFSTRNAG-IEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPPP-- 721 S+ N G +++ L TP + P + P PG G PPP Sbjct: 2298 SYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRA-SQVEPQSPGLGLRPQEPPPAQ 2356 Query: 722 -LPPPPPMSP------SWSERSVSPLRPETEARPPSRQLQALLARNI-------INAARR 767 L P PP P S+++ P PP AL R++ + A+ + Sbjct: 2357 ALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQ 2416 Query: 768 KSAS--------PRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSP-----QPARP---- 810 +S P SA A P P +P P P PP P+ R P +P RP Sbjct: 2417 SQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPE 2476 Query: 811 -----GSAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAPPRPFLYRRSP 855 GS A P + LPAGP+ + P PP + RSP Sbjct: 2477 VAFKAGSLAHTSLGAGGFP-AALPAGPAGELHAKVPSGQPPN---FVRSP 2522 Score = 53.5 bits (127), Expect = 9e-07 Identities = 82/297 (27%), Positives = 109/297 (36%), Gaps = 42/297 (14%) Query: 581 AKVSPRAASPAKPSS--LDLVPNLPKGALPPSPALP-RPSRSSPGLYTSP-GQDSLQPTA 636 A ++PRA S +P S L L P P A +P+ P P PG YT P Q L P Sbjct: 2329 APLTPRA-SQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRP 2387 Query: 637 VSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPP 696 PP P + + P FS A ++Q +S T P + A P Sbjct: 2388 QPPP---------PESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPS 2438 Query: 697 SSLDGWVSPGPWE--PGRGSSMSSPPPLPPPP-PMSPSWSERSVSPLR--------PETE 745 + SP P+ P R S PL PP P P + ++ S P Sbjct: 2439 PVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAAL 2498 Query: 746 ARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSPPRA------PPPPPPPPPPP 799 P+ +L A + R + G +P F+ P+A PP P P PP Sbjct: 2499 PAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPP 2558 Query: 800 PR------MRSPQPARPGSA--AVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAPPRP 848 P P +P S V F P S P GPSS ++ S +P RP Sbjct: 2559 PHGINSHFGPGPTLGKPQSTNYTVATGNFHP---SGSPLGPSSGSTGESYGLSPLRP 2612 Score = 53.5 bits (127), Expect = 9e-07 Identities = 153/713 (21%), Positives = 246/713 (34%), Gaps = 136/713 (19%) Query: 238 RTARPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSRS--PMV 295 R P + AP G + P+L H +PQ P P + P P + + + P Sbjct: 4282 RPQGPPRLPAPPGA--LSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPT 4339 Query: 296 ERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSSHL- 354 + P E P A +TL + L W PP L + P+ S L Sbjct: 4340 HPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPW--DPPDN--LAETQKPEQSSLV 4395 Query: 355 -------KGQAVP-ASKTGILEE-----------SMARRGSRK-------SMFTFVEKPK 388 GQ VP AS+ I +E S+ R + + S + P+ Sbjct: 4396 PGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPR 4455 Query: 389 VTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPFA-LGAEASNFQQ--EPAPRDRASPAAA 445 LL + A + +G G+ E + ++ + +Q + P ++ AA Sbjct: 4456 SEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAAR 4515 Query: 446 EEVVPEWASCLK-SPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPE 504 + + P+ K S R+ + K L + G A +Q + E ++ + E Sbjct: 4516 KPLTPKPKRVQKASDRLVSSRK-----KLRKEDGVRASEALLKQLKQELSLLPLT----E 4566 Query: 505 LARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPE------ 558 A + ++ P P N R A S A Y L +N + P Sbjct: 4567 PAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSSL 4626 Query: 559 PTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSR 618 P PP + + ++P +E + P+ A+ A+ S L +L ALP P Sbjct: 4627 PPTPPPSVQQKMVNGVTPSEELGE-HPKDAASARDSERALRDTSEVKSLDLLAALPTPPH 4685 Query: 619 S-SPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQD 677 + + + +DS P ++ P S S ++APR F +G Q+ Sbjct: 4686 NQTEDVRMESDEDSDSPDSIVPA----------SSPESILGEEAPR--FPHLGSGRWEQE 4733 Query: 678 RRESLPTSPPWTPGASRP------PSSLDGWVSPGP-----WEPGRGSSMS--------- 717 R P P P AS P P G PG WE G+GS +S Sbjct: 4734 DRALSPVIP-LIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAA 4792 Query: 718 ---------------------SPPPLPPPPPM------------SPSWSERSVSPLRPET 744 S L P P P E+ + P+T Sbjct: 4793 AKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDT 4852 Query: 745 --------EARPPSRQLQALLARNIINAARRKSASP----RSAGAENPRPFSPPRAPPPP 792 +A P L++ L +I++ +++S +P + + N + PP Sbjct: 4853 GPDWLKQFDAVLPGYTLKSQL--DILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPP 4910 Query: 793 PPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAP 845 P P PPP +P PA P + + P+ P+P+ +SP S P P Sbjct: 4911 PEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKP 4963 Score = 41.6 bits (96), Expect = 0.003 Identities = 137/619 (22%), Positives = 191/619 (30%), Gaps = 83/619 (13%) Query: 272 PQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLA 331 PQP +L P I SP +PA F PP + +P Sbjct: 2108 PQPGALGSPPPAAAPTIFIGSPT---------TPAGLSTSADGFLKPPAGSVPGPDSPGE 2158 Query: 332 SWVRSPPSYSVLYPSSDP----KSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKP 387 +++ PP PS DP + L+ + A T S ++ M +P Sbjct: 2159 LFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRP 2218 Query: 388 --------KVTPNPDLLDLVQTADE--KRRQRDQGEVGVEEEPFALGAEASNFQQEPAP- 436 TP T D K R + V E P G +AS P P Sbjct: 2219 GAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPF 2278 Query: 437 -RDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYV 495 R + +E + + P + P +L K +++ + V Sbjct: 2279 GESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQV 2338 Query: 496 IESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRS-PARTPPASLYHGYLPENGV 554 S + P P +L S P + P FR S + P PP Sbjct: 2339 EPQSPGLGLRPQEPPPAQALAPS---PPSHPDIFRPGSYTDPYAQPP------------- 2382 Query: 555 LRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRA-ASPAKPSSLD--LVPN-LPKGALPPS 610 L P P PP S L P P+ R ASP SS L P L A PS Sbjct: 2383 LTPRPQPPPP----ESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPS 2438 Query: 611 PALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSF---S 667 P PR + SP S P S P D P +P P Q P +F S Sbjct: 2439 PVTPR--------FQSPDPYSRPP---SRPQSRD--PFAPLH--KPPRPQPPEVAFKAGS 2483 Query: 668 TRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPP 727 + + A +LP P A P +V PG G+ + +P P+ P Sbjct: 2484 LAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVR----SPGTGAFVGTPSPMRFTFP 2539 Query: 728 MSPSWSERSVSPLRPETEARPP---------SRQLQALLARNIINAARRKSASPRSAGAE 778 + E S+ P P+ PP L + N A S G Sbjct: 2540 QAVG--EPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPS 2597 Query: 779 NPRPFSPPRAPPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSP 838 + P PP PPP P A+ +P+ + P + Sbjct: 2598 SGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLA 2657 Query: 839 RSPLPAPPRPFLYRRSPTD 857 + LP P + S T+ Sbjct: 2658 TAELPGTQDPGMSGLSQTE 2676 Score = 39.7 bits (91), Expect = 0.013 Identities = 52/180 (28%), Positives = 71/180 (39%), Gaps = 42/180 (23%) Query: 647 PVSPSRAWS-PRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWT-------PGASRPPS- 697 P SP+RA + P+ +A P + G+E + S T P W PG + Sbjct: 4820 PESPARAGTEPKKGEAEGPG--GKEKGLEGK----SPDTGPDWLKQFDAVLPGYTLKSQL 4873 Query: 698 ---SLDGWVSPGPWEPGRGS-----------SMSSPPPLPPPPPMSPSWSERSVSPLRPE 743 SL SP P P + S +S+PPP P PP SPL P Sbjct: 4874 DILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPP---------PSPLAP- 4923 Query: 744 TEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMR 803 + A PP+ L L + S P ++ E+ RP PRA PP PPR++ Sbjct: 4924 SPASPPTEPLVELPTEPLAEPP-VPSPLPLASSPESARP--KPRARPPEEGEDSRPPRLK 4980 Score = 38.1 bits (87), Expect = 0.037 Identities = 60/229 (26%), Positives = 77/229 (33%), Gaps = 46/229 (20%) Query: 608 PPSPALPRPSRSS-------PGLYTSPGQDSLQPTAVSPPYG-------GDISPVSPSRA 653 P P L RP +++ PG GQ L + P G G ++ R Sbjct: 4155 PQQPMLERPMQNNTGPQPPKPGPVLQSGQ-GLPGVGIMPTVGQLRAQLQGVLAKNPQLRH 4213 Query: 654 WSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPP--------SSLDGWVSP 705 SP+ +Q + R + Q + T P PG P L G+ P Sbjct: 4214 LSPQQQQQLQALLMQR----QLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGP 4269 Query: 706 --GPW-EPGRGSSMSSPPPLPPPP-PMSPSWSERSVSPLRPETEARPPSRQLQALLARNI 761 GP E G G PP LP PP +S V P P + + P R Q Sbjct: 4270 QTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQL------ 4323 Query: 762 INAARRKSASPRSA-GAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPAR 809 SP S E P + P P P P PPP SP A+ Sbjct: 4324 --------PSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQ 4364 Score = 37.7 bits (86), Expect = 0.049 Identities = 150/699 (21%), Positives = 240/699 (34%), Gaps = 108/699 (15%) Query: 57 PPPAEVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPP----ATVVPQSLPLS 112 PPPA+ +P+ + ++ P + T P + PP T Q PP + P+SLP Sbjct: 2352 PPPAQALAPSPPSHPDIFRPGS-YTDPYAQ----PPLTPRPQPPPPESCCALPPRSLPSD 2406 Query: 113 SIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTSTFSR 172 + + Q S+ P + P L A+ +P S D S P + + Sbjct: 2407 PFSRVPASPQSQSSSQSPLT-PRPLSAEAFCPSPVTPRFQSP---DPYSRPPSRPQSRDP 2462 Query: 173 EATLI--PSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLA 230 A L P +PP F + SL + +G A P E+H A Sbjct: 2463 FAPLHKPPRPQPPEVAFKAGSL-----------AHTSLGAGGFPAALPAGPAGELH---A 2508 Query: 231 KPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGE-------KAPAPQPPSLPDRSPR 283 K PS +P GT +P R F + K P PQP P P Sbjct: 2509 KVPS-----GQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPP---PH 2560 Query: 284 PQRHIMSRSPMVERRMMGQRSPASER-RPLGNFTAPPTYT--ETLSTAPLASWVRSPPSY 340 P + + + A+ P G+ P + + E+ +PL PP Sbjct: 2561 GINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPP-- 2618 Query: 341 SVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKV--TPNPDLLDL 398 P+ D +L A + ++GI R M + + ++ T +P + L Sbjct: 2619 ----PAPDGSLPYLSHGA--SQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGL 2672 Query: 399 VQTADEKRRQRDQ-GEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLK 457 QT EK+RQR + E+ + ++ Q+ +++ + AAA V S Sbjct: 2673 SQTELEKQRQRQRLRELLIRQQ----------IQRNTLRQEKETAAAAAGAVGPPGSWGA 2722 Query: 458 SPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPE--LARCPSPT--M 513 P A + Q + + L S++ ++ S + L+R P P Sbjct: 2723 EPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPS 2782 Query: 514 SLPSSWKYPTNAPGAFRVASRSPARTP---------------PASLYHGYLPENGVLRPE 558 S+ + + AF + P P A+ + P Sbjct: 2783 SMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPG 2842 Query: 559 PTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALP---PSPALPR 615 P P + + + P + P A PA+ ++L N+ KG P P P Sbjct: 2843 PELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQ--FIELRHNVQKGLGPGGTPFPGQGP 2900 Query: 616 PSRSSPGLY-TSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIE 674 P R P Y S L P + + P PS +P + P+ T+ Sbjct: 2901 PQR--PRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKG---- 2954 Query: 675 AQDRRESLPTSPPWTPGASRPPSSLD-GWVSPGPWEPGR 712 PT P +RPPSS + G +P E G+ Sbjct: 2955 --------PTLPTGLELVNRPPSSTELGRPNPLALEAGK 2985 Score = 37.7 bits (86), Expect = 0.049 Identities = 26/81 (32%), Positives = 31/81 (38%), Gaps = 16/81 (19%) Query: 780 PRPFSPPRAPPPP--------------PPPPPPPPRMRSPQPARPGSAAVPGAAFAP--I 823 PRP PPR P PP PPP P + P S+ +P A P Sbjct: 4281 PRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTH 4340 Query: 824 PRSPLPAGPSSCTSPRSPLPA 844 P +P P GP+ P PA Sbjct: 4341 PGTPKPQGPTLEPPPGRVSPA 4361 Score = 35.4 bits (80), Expect = 0.24 Identities = 72/293 (24%), Positives = 105/293 (35%), Gaps = 53/293 (18%) Query: 579 EPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVS 638 EP +V P S + S L LV P+ P S L P R PGQ Q + + Sbjct: 4061 EPGEVKP---SLSGDSQLLLVQPQPQPQ-PSSLQLQPPLRL-------PGQQQQQVSLLH 4109 Query: 639 PPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTS--PPWTPGASRPP 696 GG S + S + +A + D+ S+ + P P RP Sbjct: 4110 TAGGG-----SHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPM 4164 Query: 697 SSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERS----VSPLRPETEARPPSRQ 752 + + GP P G + S LP M R+ V P+ P +Q Sbjct: 4165 QN-----NTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQ 4219 Query: 753 --LQALLARNIINAARRKSASP--RSAGAEN----------------PRPFSPPRAPPPP 792 LQALL + + ++ +P + G + P P + P Sbjct: 4220 QQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGA 4279 Query: 793 PPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAP 845 P P PPR+ PA PG+ + G P+ +P P+ P P S LP+P Sbjct: 4280 GPRPQGPPRL----PAPPGALST-GPVLGPVHPTPPPSSPQEPKRP-SQLPSP 4326 Score = 35.0 bits (79), Expect = 0.32 Identities = 29/109 (26%), Positives = 42/109 (38%), Gaps = 16/109 (14%) Query: 550 PENGVLR-----PEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPK 604 P+ G L+ P P P P P+ P +P +SP +P +P+ Sbjct: 4269 PQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPS--- 4325 Query: 605 GALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRA 653 PS LP ++ P T PG Q + PP G +SP + A Sbjct: 4326 ----PSSQLPTEAQLPP---THPGTPKPQGPTLEPP-PGRVSPAAAQLA 4366 Score = 33.1 bits (74), Expect = 1.2 Identities = 36/108 (33%), Positives = 40/108 (37%), Gaps = 21/108 (19%) Query: 535 SPARTPPASLYHGYLPENGVLR------PEPTKQPPYQLRPSLFVLSPIKEPAKVSPRA- 587 SPA PP + Y N +R PE PP L PS SP EP P Sbjct: 4883 SPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPS--PASPPTEPLVELPTEP 4940 Query: 588 -ASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQP 634 A P PS L L A P A P+P P G+DS P Sbjct: 4941 LAEPPVPSPLPL-------ASSPESARPKPRARPP----EEGEDSRPP 4977 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 93.2 bits (230), Expect = 1e-18 Identities = 117/452 (25%), Positives = 164/452 (36%), Gaps = 96/452 (21%) Query: 420 PFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGK 479 PF L +++ Q+E + + E+ PE +K P Q PKP P Q G Sbjct: 175 PFDLISDSEASQEETTKKQKV--VQKEQGKPE--GIIKPPLQQQPPKPIPKQQ-----GP 225 Query: 480 GAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPART 539 G + +Q K + SS PE + P P + P +T Sbjct: 226 GRD--PLQQDGTPKSI---SSQQPEKIKSQPPGTGKPI----------------QGPTQT 264 Query: 540 PPASLYHGYLP-ENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDL 598 P H LP + RP+ TKQ + I V P SP+KP Sbjct: 265 PQTD--HAKLPLQRDASRPQ-TKQ------------ADIVRGESVKPSLPSPSKPPIQQP 309 Query: 599 VPNLPKGALP------PSPALP--RPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSP 650 P P P P PA P +PS + L PG +++P V PP G P P Sbjct: 310 TPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPG--TVKPP-VQPP-GTTKPPAQP 365 Query: 651 SRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEP 710 P A+Q S+ G +A + + +P PG ++PP+ G P +P Sbjct: 366 LGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQP 425 Query: 711 GRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSA 770 G S +P P + +P++ + P++Q A Sbjct: 426 GLQSPAKAPGP--------------TKTPVQQPGPGKIPAQQ-----------------A 454 Query: 771 SPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPARPGSAAVPG---AAFAPIPRSP 827 P A+ P PP P P PPP P P P +PGSA P + P P+ P Sbjct: 455 GPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQP 514 Query: 828 LPAGPS----SCTSPRSPLPAPPRPFLYRRSP 855 PA PS T P S P +P + SP Sbjct: 515 GPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSP 546 Score = 84.3 bits (207), Expect = 5e-16 Identities = 184/845 (21%), Positives = 287/845 (33%), Gaps = 128/845 (15%) Query: 51 QQSSPAPPPAEVHSPAADVNQ-NLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSL 109 QQ +P PPA+ P + +Q A P A + T + P PP T P + Sbjct: 307 QQPTPGKPPAQ--QPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQ 364 Query: 110 PLSSIQQNSSEAQLPSNGTG---PASKPSTLCADGQP----QAPAEEVRCSTLLIDKVST 162 PL A+ P+ TG P+S+ A QP + PA++ + +V T Sbjct: 365 PLGP-------AKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGT 417 Query: 163 PATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAA--TTPTK 220 P P + PA + + QP + A Q G+ +A T PTK Sbjct: 418 PKPLAQQ--------PGLQSPAKAPGPTKTPVQ-QPGPGKIPAQQAGPGKTSAQQTGPTK 468 Query: 221 VYSEVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPSLPDR 280 S++ AKPP A+P Q PG + P + + PA P P Sbjct: 469 PPSQLPGP-AKPPPQQPGPAKP-PPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS 526 Query: 281 SPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSY 340 + P + S P + Q SPA +P + P ++T S PL PP+ Sbjct: 527 TKPPSQQPGSAKPSAQ-----QPSPA---KPSAQQSTKPV-SQTGSGKPL-----QPPTV 572 Query: 341 SVLYPSS-DPKSSHLKGQAVPASKTGILEESMARRGS----RKSMFTFVEKPKVTPNPDL 395 S PS+ P S L P T L + + + + T PNP L Sbjct: 573 S---PSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHL 629 Query: 396 LDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASC 455 ++ + + + ALG + + P P+ + +P V Sbjct: 630 TEVKEWLCLNCQMKR-----------ALGGDLAPVPSSPQPKLKTAPVTTTSAV------ 672 Query: 456 LKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSL 515 +K P+P Q + + ++ +L++ P P Sbjct: 673 -------SKSSPQPQQTSPK---------------------KDAAPKQDLSKAPEPKKP- 703 Query: 516 PSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLS 575 P K PT + + A+ PP + + + +P P K+P PS + Sbjct: 704 PPLVKQPT-----LHGSPSAKAKQPPEA--------DSLSKPAPPKEPSV---PSEQDKA 747 Query: 576 PIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPT 635 P+ + P+ P + DLV + P P+ S++ DS +P+ Sbjct: 748 PVADDKPKQPKMVKP----TTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPS 803 Query: 636 AVSPPYGGDISPVSPSRAWSPRA--KQAPRPSFSTRNAGIE----AQDRRESLPTSPPWT 689 PP G +SP P + K P S+ + G + Q + E + Sbjct: 804 QSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMS 863 Query: 690 PGASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPL-RPETEARP 748 P P PGP P G ++ +P P P S +S S P+++ Sbjct: 864 PKPDAKPMPKGSPTPPGP-RPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTT 922 Query: 749 PSRQLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPA 808 P + L + + S +AG P S P AP P P PP + P P Sbjct: 923 PQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGP-PK 981 Query: 809 RPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAPPRPFLYRRSPTDSD-VSLDSEDS 867 G A A P+ + P R ++ P D SL +E Sbjct: 982 STGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQ 1041 Query: 868 GAKSP 872 A P Sbjct: 1042 KAVLP 1046 Score = 70.9 bits (172), Expect = 5e-12 Identities = 102/423 (24%), Positives = 150/423 (35%), Gaps = 59/423 (13%) Query: 401 TADEKRRQRDQGEV-GVEEEPFALGAEASNFQQEPAPRDR----ASPAAAEEVVPEWASC 455 T +K Q++QG+ G+ + P +Q+ RD +P + PE Sbjct: 190 TKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPE--KI 247 Query: 456 LKSPRIQAKPKPKPNQNLSEASGK-GAELYARRQSRMEKYVIESSSHTPELARCPSPTMS 514 P KP P Q K + A R + ++ S P L P + Sbjct: 248 KSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQ 307 Query: 515 LPSSWKYPTNAPGAFRVASRSPARTP--PASLYHGYLPENGVLRPEPTKQPPYQLRPSLF 572 P+ K P PG + + PA+ P P+ L + G ++P QPP +P Sbjct: 308 QPTPGKPPAQQPGHEK-SQPGPAKPPAQPSGLTKPLAQQPGTVKPPV--QPPGTTKPPAQ 364 Query: 573 VLSPIKEPAKVS----PRAASP-----AKPSSLDLVP-NLPKGALPPSPAL--PRPSRSS 620 L P K PA+ + P + P A+P + P P A PP+ + P+P Sbjct: 365 PLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQ 424 Query: 621 PGLYTSPGQDSLQPTAVSPPYGGDI--SPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDR 678 PGL + T V P G I P + + + PS A Q Sbjct: 425 PGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQP 484 Query: 679 RESLPTSPPWTPGASRPPSSLDGWVSP-----GPWEPGRGSSMSSPPPLPPPPPMSPSWS 733 + P PP PG+++PPS G P GP +P S+ PP P PS Sbjct: 485 GPAKP--PPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQ 542 Query: 734 ERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPP 793 + S A+P ++Q K S +G +P PP P Sbjct: 543 QPS--------PAKPSAQQ-------------STKPVSQTGSG----KPLQPPTVSPSAK 577 Query: 794 PPP 796 PP Sbjct: 578 QPP 580 Score = 54.3 bits (129), Expect = 5e-07 Identities = 124/543 (22%), Positives = 177/543 (32%), Gaps = 106/543 (19%) Query: 384 VEKPKVTPNPDLLDLVQTADEKRRQRDQGEV--GVEEEPFALGAEASNFQQEPAP----- 436 ++ P TP D L D R Q Q ++ G +P +L + + Q+P P Sbjct: 258 IQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKP-SLPSPSKPPIQQPTPGKPPA 316 Query: 437 ----RDRASPAAAEEVVPEWASCLKSPRIQAK-----PKPKPNQNLSEASGKGAELYARR 487 +++ P A+ P S L P Q P P A G + Sbjct: 317 QQPGHEKSQPGPAKP--PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQ 374 Query: 488 QSRMEKYVIESS-----SHTPELARCPS--PTMSLPSSWKYPTNAPGAFRVASRSPARTP 540 Q+ EK E + P + + P+ P + P + + T P A + +SPA+ P Sbjct: 375 QTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAP 434 Query: 541 PASLYHGYLPENGVLRPEPTKQPPYQLRP---SLFVLSPIKEP------AKVSPRAASPA 591 + + V +P P K P Q P S P K P AK P+ PA Sbjct: 435 GPT-------KTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPA 487 Query: 592 KP---------------SSLDLVPNLPKGALPPSPALP---RPSRSSPG------LYTSP 627 KP S P P G PSP P +P PG SP Sbjct: 488 KPPPQQPGSAKPPSQQPGSTKPPPQQP-GPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSP 546 Query: 628 GQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPR--------------------PSFS 667 + S Q + G P+ P SP AKQ P P + Sbjct: 547 AKPSAQQSTKPVSQTGSGKPLQPPTV-SPSAKQPPSQGLPKTICPLCNTTELLLHVPEKA 605 Query: 668 TRNAGIEAQDRRESLPTSPP---------WTPGASRPPSSLDGWVSPGPWEPGRGSSMSS 718 N E Q SL P W + +L G ++P P SS Sbjct: 606 NFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVP---------SS 656 Query: 719 PPPLPPPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAE 778 P P P++ + + SP +T + + Q L P G+ Sbjct: 657 PQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSP 716 Query: 779 NPRPFSPPRAPPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSP 838 + + PP A P PP P + S Q P + P P + L + S+ T P Sbjct: 717 SAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKP 776 Query: 839 RSP 841 P Sbjct: 777 DIP 779 Score = 52.0 bits (123), Expect = 2e-06 Identities = 66/247 (26%), Positives = 88/247 (35%), Gaps = 62/247 (25%) Query: 608 PPSP--ALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPS 665 PPS ALP + S +TS + A P G SPS + P PRP Sbjct: 2343 PPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSG------SPSVSSLPAK---PRPF 2393 Query: 666 FSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPP 725 F + + I AQ P PP P PP PPP PPP Sbjct: 2394 FRSSSLDISAQ------PPPPPPPPPPPPPP----------------------PPPPPPP 2425 Query: 726 PPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSP 785 P P+ + ++ P + T A P + A + +A RS G R + Sbjct: 2426 PLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLET----TAVLRSNGLPVTRICT- 2480 Query: 786 PRAPPPPPPPPPPPPR----MRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRSP 841 APPP PP P P P+P++P P +P P P T+ + P Sbjct: 2481 -TAPPPVPPKPSSIPSGLVFTHRPEPSKP-------------PIAPKPVIPQLPTTTQKP 2526 Query: 842 LPAPPRP 848 P+P Sbjct: 2527 TDIHPKP 2533 Score = 50.4 bits (119), Expect = 7e-06 Identities = 134/639 (20%), Positives = 218/639 (34%), Gaps = 113/639 (17%) Query: 50 AQQSSPAPPPAEVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSL 109 AQQ+ P PP+++ PA Q P P S PP +Q P +T P Sbjct: 461 AQQTGPTKPPSQLPGPAKPPPQ---QPGPAKPPPQQPGSAKPP----SQQPGSTKPPPQQ 513 Query: 110 PLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAE-EVRCSTLLIDKVSTPATTTS 168 P + Q P + P+ +P + Q +PA+ + ST + + T + Sbjct: 514 PGPA----KPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ-----TGSG 564 Query: 169 TFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYS----- 223 + T+ PS++ P S + ++ L++ ++ + T V S Sbjct: 565 KPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFN 624 Query: 224 -EVHFTLAKPPSVVNRTARPF--GIQAPGGTS---QMERSPMLERRHFGEKAPAPQPPSL 277 H T K +N + G AP +S +++ +P+ + +P PQ S Sbjct: 625 PNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTS- 683 Query: 278 PDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSP 337 P + P++ +S++P ++ + P P PP AP S Sbjct: 684 PKKDAAPKQD-LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKE--PSV 740 Query: 338 PSYSVLYPSSDPK--------------------------SSHLKGQA----VPASKTGIL 367 PS P +D K SS ++ QA P KT Sbjct: 741 PSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSA 800 Query: 368 E--ESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGA 425 + +S G + S F P+ + ++ + E + Q+ V +EEP Sbjct: 801 KPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQT 860 Query: 426 EAS----------NFQQEPAPRDRAS---PAAAEEVVPEWAS---CLKSPRIQAKPKPKP 469 + S P PR A P + P+ S L I PK +P Sbjct: 861 KMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQP 920 Query: 470 NQNLSEASGK----GAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNA 525 +GK GA ++++ +S+ A P P + + Sbjct: 921 TTPQETVTGKLFGFGASIFSQ------------ASNLISTAGQPGP---------HSQSG 959 Query: 526 PGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLR---PSLFVLSPIKEPAK 582 PGA + +P++ PP S G G P P K P + P+ L P E A Sbjct: 960 PGAPMKQAPAPSQ-PPTS--QGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAP 1016 Query: 583 VSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSP 621 R + KP + +L A P LP SP Sbjct: 1017 TVKRTETEKKPPPIKDSKSLT--AEPQKAVLPTKLEKSP 1053 Score = 38.1 bits (87), Expect = 0.037 Identities = 55/228 (24%), Positives = 76/228 (33%), Gaps = 47/228 (20%) Query: 576 PIKEPAKVSPRAAS-PAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQP 634 P + SP +S PAKP +L A PP P P P P P Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPP-----------PP 2420 Query: 635 TAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQD--------RRESLPTS- 685 PP P SP P+ K +T +A R LP + Sbjct: 2421 PPPPPPLP---PPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTR 2477 Query: 686 ------PPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPP--PMSPSWSERSV 737 PP P S PS L P P S PP+ P P P P+ +++ Sbjct: 2478 ICTTAPPPVPPKPSSIPSGLVFTHRPEP----------SKPPIAPKPVIPQLPTTTQKPT 2527 Query: 738 SPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSP 785 + +P L + + N++ +A K SP S + + SP Sbjct: 2528 -----DIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSP 2570 Score = 33.5 bits (75), Expect = 0.92 Identities = 67/336 (19%), Positives = 110/336 (32%), Gaps = 37/336 (11%) Query: 462 QAKPKPKPNQNLSEASGKGAELYARRQSRME------KYVIESSSHTPELARCPSPTMSL 515 +A P P P ++ S+ + ++ ++ E K ++E T + + P + Sbjct: 1133 KASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTD 1192 Query: 516 PSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLS 575 + A + + P LPE L PE K + +P L Sbjct: 1193 QKQEESKLEKDKASALQEKKP------------LPEEKKLIPEEEKIRSEEKKPLLEEKK 1240 Query: 576 PIKEPAKVSPRAASPA-KPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQP 634 P E K+ P A + A + DL+ + + A P G + L Sbjct: 1241 PTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGL-- 1298 Query: 635 TAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASR 694 P G S + K+ P+P + + +E + T +S+ Sbjct: 1299 -----PSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDT-SSSQ 1352 Query: 695 PPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPP-------MSPSWSERSVSPLRPETEAR 747 P S G G G SS+ P L P S+S+ S SP P A+ Sbjct: 1353 QPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQES-SPSSPSDLAK 1411 Query: 748 PPSRQLQALLAR--NIINAARRKSASPRSAGAENPR 781 S L L A+ + + K P E P+ Sbjct: 1412 LESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPK 1447 Score = 33.1 bits (74), Expect = 1.2 Identities = 36/141 (25%), Positives = 54/141 (38%), Gaps = 18/141 (12%) Query: 659 KQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSM-- 716 K P + + + Q +S SP + S P P P E G S + Sbjct: 3551 KHISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKK----RPTPLEIGYSSHLRA 3606 Query: 717 SSPPPLPPPPPMSPSWSERSVSPLRP----ETEARPPSRQLQALLARNII---NAARRKS 769 S L P PP SP +SPL P E+ P + L ++ + + A+ Sbjct: 3607 DSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPP 3666 Query: 770 ASPRSA-----GAENPRPFSP 785 ASP++A +P+P SP Sbjct: 3667 ASPKTAKMMQRSMSDPKPLSP 3687 Score = 31.6 bits (70), Expect = 3.5 Identities = 32/135 (23%), Positives = 53/135 (39%), Gaps = 15/135 (11%) Query: 488 QSRMEKYVIESSSHTPELARCPSP-TMSLPSSWKYPTNAPGAFRVASR-----------S 535 Q+ +++ + +L SP T SS PT AP ++ S S Sbjct: 3861 QTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQAPTSYTQQSHFEQQTLYHQQVS 3920 Query: 536 PARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSS 595 P +T P + ++P PT QP YQL + V I++ + + P S+ Sbjct: 3921 PYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMV---IQQKPRQTTLYLEPKITSN 3977 Query: 596 LDLVPNLPKGALPPS 610 +++ N P P S Sbjct: 3978 YEVIRNQPLMIAPVS 3992 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 93.2 bits (230), Expect = 1e-18 Identities = 117/452 (25%), Positives = 164/452 (36%), Gaps = 96/452 (21%) Query: 420 PFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGK 479 PF L +++ Q+E + + E+ PE +K P Q PKP P Q G Sbjct: 175 PFDLISDSEASQEETTKKQKV--VQKEQGKPE--GIIKPPLQQQPPKPIPKQQ-----GP 225 Query: 480 GAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPART 539 G + +Q K + SS PE + P P + P +T Sbjct: 226 GRD--PLQQDGTPKSI---SSQQPEKIKSQPPGTGKPI----------------QGPTQT 264 Query: 540 PPASLYHGYLP-ENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDL 598 P H LP + RP+ TKQ + I V P SP+KP Sbjct: 265 PQTD--HAKLPLQRDASRPQ-TKQ------------ADIVRGESVKPSLPSPSKPPIQQP 309 Query: 599 VPNLPKGALP------PSPALP--RPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSP 650 P P P P PA P +PS + L PG +++P V PP G P P Sbjct: 310 TPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPG--TVKPP-VQPP-GTTKPPAQP 365 Query: 651 SRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEP 710 P A+Q S+ G +A + + +P PG ++PP+ G P +P Sbjct: 366 LGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQP 425 Query: 711 GRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSA 770 G S +P P + +P++ + P++Q A Sbjct: 426 GLQSPAKAPGP--------------TKTPVQQPGPGKIPAQQ-----------------A 454 Query: 771 SPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPARPGSAAVPG---AAFAPIPRSP 827 P A+ P PP P P PPP P P P +PGSA P + P P+ P Sbjct: 455 GPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQP 514 Query: 828 LPAGPS----SCTSPRSPLPAPPRPFLYRRSP 855 PA PS T P S P +P + SP Sbjct: 515 GPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSP 546 Score = 84.3 bits (207), Expect = 5e-16 Identities = 184/845 (21%), Positives = 287/845 (33%), Gaps = 128/845 (15%) Query: 51 QQSSPAPPPAEVHSPAADVNQ-NLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSL 109 QQ +P PPA+ P + +Q A P A + T + P PP T P + Sbjct: 307 QQPTPGKPPAQ--QPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQ 364 Query: 110 PLSSIQQNSSEAQLPSNGTG---PASKPSTLCADGQP----QAPAEEVRCSTLLIDKVST 162 PL A+ P+ TG P+S+ A QP + PA++ + +V T Sbjct: 365 PLGP-------AKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGT 417 Query: 163 PATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAA--TTPTK 220 P P + PA + + QP + A Q G+ +A T PTK Sbjct: 418 PKPLAQQ--------PGLQSPAKAPGPTKTPVQ-QPGPGKIPAQQAGPGKTSAQQTGPTK 468 Query: 221 VYSEVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPSLPDR 280 S++ AKPP A+P Q PG + P + + PA P P Sbjct: 469 PPSQLPGP-AKPPPQQPGPAKP-PPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS 526 Query: 281 SPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSY 340 + P + S P + Q SPA +P + P ++T S PL PP+ Sbjct: 527 TKPPSQQPGSAKPSAQ-----QPSPA---KPSAQQSTKPV-SQTGSGKPL-----QPPTV 572 Query: 341 SVLYPSS-DPKSSHLKGQAVPASKTGILEESMARRGS----RKSMFTFVEKPKVTPNPDL 395 S PS+ P S L P T L + + + + T PNP L Sbjct: 573 S---PSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHL 629 Query: 396 LDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASC 455 ++ + + + ALG + + P P+ + +P V Sbjct: 630 TEVKEWLCLNCQMKR-----------ALGGDLAPVPSSPQPKLKTAPVTTTSAV------ 672 Query: 456 LKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSL 515 +K P+P Q + + ++ +L++ P P Sbjct: 673 -------SKSSPQPQQTSPK---------------------KDAAPKQDLSKAPEPKKP- 703 Query: 516 PSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLS 575 P K PT + + A+ PP + + + +P P K+P PS + Sbjct: 704 PPLVKQPT-----LHGSPSAKAKQPPEA--------DSLSKPAPPKEPSV---PSEQDKA 747 Query: 576 PIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPT 635 P+ + P+ P + DLV + P P+ S++ DS +P+ Sbjct: 748 PVADDKPKQPKMVKP----TTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPS 803 Query: 636 AVSPPYGGDISPVSPSRAWSPRA--KQAPRPSFSTRNAGIE----AQDRRESLPTSPPWT 689 PP G +SP P + K P S+ + G + Q + E + Sbjct: 804 QSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMS 863 Query: 690 PGASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPL-RPETEARP 748 P P PGP P G ++ +P P P S +S S P+++ Sbjct: 864 PKPDAKPMPKGSPTPPGP-RPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTT 922 Query: 749 PSRQLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPA 808 P + L + + S +AG P S P AP P P PP + P P Sbjct: 923 PQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGP-PK 981 Query: 809 RPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAPPRPFLYRRSPTDSD-VSLDSEDS 867 G A A P+ + P R ++ P D SL +E Sbjct: 982 STGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQ 1041 Query: 868 GAKSP 872 A P Sbjct: 1042 KAVLP 1046 Score = 70.9 bits (172), Expect = 5e-12 Identities = 102/423 (24%), Positives = 150/423 (35%), Gaps = 59/423 (13%) Query: 401 TADEKRRQRDQGEV-GVEEEPFALGAEASNFQQEPAPRDR----ASPAAAEEVVPEWASC 455 T +K Q++QG+ G+ + P +Q+ RD +P + PE Sbjct: 190 TKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPE--KI 247 Query: 456 LKSPRIQAKPKPKPNQNLSEASGK-GAELYARRQSRMEKYVIESSSHTPELARCPSPTMS 514 P KP P Q K + A R + ++ S P L P + Sbjct: 248 KSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQ 307 Query: 515 LPSSWKYPTNAPGAFRVASRSPARTP--PASLYHGYLPENGVLRPEPTKQPPYQLRPSLF 572 P+ K P PG + + PA+ P P+ L + G ++P QPP +P Sbjct: 308 QPTPGKPPAQQPGHEK-SQPGPAKPPAQPSGLTKPLAQQPGTVKPPV--QPPGTTKPPAQ 364 Query: 573 VLSPIKEPAKVS----PRAASP-----AKPSSLDLVP-NLPKGALPPSPAL--PRPSRSS 620 L P K PA+ + P + P A+P + P P A PP+ + P+P Sbjct: 365 PLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQ 424 Query: 621 PGLYTSPGQDSLQPTAVSPPYGGDI--SPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDR 678 PGL + T V P G I P + + + PS A Q Sbjct: 425 PGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQP 484 Query: 679 RESLPTSPPWTPGASRPPSSLDGWVSP-----GPWEPGRGSSMSSPPPLPPPPPMSPSWS 733 + P PP PG+++PPS G P GP +P S+ PP P PS Sbjct: 485 GPAKP--PPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQ 542 Query: 734 ERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPP 793 + S A+P ++Q K S +G +P PP P Sbjct: 543 QPS--------PAKPSAQQ-------------STKPVSQTGSG----KPLQPPTVSPSAK 577 Query: 794 PPP 796 PP Sbjct: 578 QPP 580 Score = 54.3 bits (129), Expect = 5e-07 Identities = 124/543 (22%), Positives = 177/543 (32%), Gaps = 106/543 (19%) Query: 384 VEKPKVTPNPDLLDLVQTADEKRRQRDQGEV--GVEEEPFALGAEASNFQQEPAP----- 436 ++ P TP D L D R Q Q ++ G +P +L + + Q+P P Sbjct: 258 IQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKP-SLPSPSKPPIQQPTPGKPPA 316 Query: 437 ----RDRASPAAAEEVVPEWASCLKSPRIQAK-----PKPKPNQNLSEASGKGAELYARR 487 +++ P A+ P S L P Q P P A G + Sbjct: 317 QQPGHEKSQPGPAKP--PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQ 374 Query: 488 QSRMEKYVIESS-----SHTPELARCPS--PTMSLPSSWKYPTNAPGAFRVASRSPARTP 540 Q+ EK E + P + + P+ P + P + + T P A + +SPA+ P Sbjct: 375 QTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAP 434 Query: 541 PASLYHGYLPENGVLRPEPTKQPPYQLRP---SLFVLSPIKEP------AKVSPRAASPA 591 + + V +P P K P Q P S P K P AK P+ PA Sbjct: 435 GPT-------KTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPA 487 Query: 592 KP---------------SSLDLVPNLPKGALPPSPALP---RPSRSSPG------LYTSP 627 KP S P P G PSP P +P PG SP Sbjct: 488 KPPPQQPGSAKPPSQQPGSTKPPPQQP-GPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSP 546 Query: 628 GQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPR--------------------PSFS 667 + S Q + G P+ P SP AKQ P P + Sbjct: 547 AKPSAQQSTKPVSQTGSGKPLQPPTV-SPSAKQPPSQGLPKTICPLCNTTELLLHVPEKA 605 Query: 668 TRNAGIEAQDRRESLPTSPP---------WTPGASRPPSSLDGWVSPGPWEPGRGSSMSS 718 N E Q SL P W + +L G ++P P SS Sbjct: 606 NFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVP---------SS 656 Query: 719 PPPLPPPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAE 778 P P P++ + + SP +T + + Q L P G+ Sbjct: 657 PQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSP 716 Query: 779 NPRPFSPPRAPPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSP 838 + + PP A P PP P + S Q P + P P + L + S+ T P Sbjct: 717 SAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKP 776 Query: 839 RSP 841 P Sbjct: 777 DIP 779 Score = 52.0 bits (123), Expect = 2e-06 Identities = 66/247 (26%), Positives = 88/247 (35%), Gaps = 62/247 (25%) Query: 608 PPSP--ALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPS 665 PPS ALP + S +TS + A P G SPS + P PRP Sbjct: 2343 PPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSG------SPSVSSLPAK---PRPF 2393 Query: 666 FSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPP 725 F + + I AQ P PP P PP PPP PPP Sbjct: 2394 FRSSSLDISAQ------PPPPPPPPPPPPPP----------------------PPPPPPP 2425 Query: 726 PPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSP 785 P P+ + ++ P + T A P + A + +A RS G R + Sbjct: 2426 PLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLET----TAVLRSNGLPVTRICT- 2480 Query: 786 PRAPPPPPPPPPPPPR----MRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRSP 841 APPP PP P P P+P++P P +P P P T+ + P Sbjct: 2481 -TAPPPVPPKPSSIPSGLVFTHRPEPSKP-------------PIAPKPVIPQLPTTTQKP 2526 Query: 842 LPAPPRP 848 P+P Sbjct: 2527 TDIHPKP 2533 Score = 50.4 bits (119), Expect = 7e-06 Identities = 134/639 (20%), Positives = 218/639 (34%), Gaps = 113/639 (17%) Query: 50 AQQSSPAPPPAEVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSL 109 AQQ+ P PP+++ PA Q P P S PP +Q P +T P Sbjct: 461 AQQTGPTKPPSQLPGPAKPPPQ---QPGPAKPPPQQPGSAKPP----SQQPGSTKPPPQQ 513 Query: 110 PLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAE-EVRCSTLLIDKVSTPATTTS 168 P + Q P + P+ +P + Q +PA+ + ST + + T + Sbjct: 514 PGPA----KPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ-----TGSG 564 Query: 169 TFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYS----- 223 + T+ PS++ P S + ++ L++ ++ + T V S Sbjct: 565 KPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFN 624 Query: 224 -EVHFTLAKPPSVVNRTARPF--GIQAPGGTS---QMERSPMLERRHFGEKAPAPQPPSL 277 H T K +N + G AP +S +++ +P+ + +P PQ S Sbjct: 625 PNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTS- 683 Query: 278 PDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSP 337 P + P++ +S++P ++ + P P PP AP S Sbjct: 684 PKKDAAPKQD-LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKE--PSV 740 Query: 338 PSYSVLYPSSDPK--------------------------SSHLKGQA----VPASKTGIL 367 PS P +D K SS ++ QA P KT Sbjct: 741 PSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSA 800 Query: 368 E--ESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGA 425 + +S G + S F P+ + ++ + E + Q+ V +EEP Sbjct: 801 KPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQT 860 Query: 426 EAS----------NFQQEPAPRDRAS---PAAAEEVVPEWAS---CLKSPRIQAKPKPKP 469 + S P PR A P + P+ S L I PK +P Sbjct: 861 KMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQP 920 Query: 470 NQNLSEASGK----GAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNA 525 +GK GA ++++ +S+ A P P + + Sbjct: 921 TTPQETVTGKLFGFGASIFSQ------------ASNLISTAGQPGP---------HSQSG 959 Query: 526 PGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLR---PSLFVLSPIKEPAK 582 PGA + +P++ PP S G G P P K P + P+ L P E A Sbjct: 960 PGAPMKQAPAPSQ-PPTS--QGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAP 1016 Query: 583 VSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSP 621 R + KP + +L A P LP SP Sbjct: 1017 TVKRTETEKKPPPIKDSKSLT--AEPQKAVLPTKLEKSP 1053 Score = 38.1 bits (87), Expect = 0.037 Identities = 55/228 (24%), Positives = 76/228 (33%), Gaps = 47/228 (20%) Query: 576 PIKEPAKVSPRAAS-PAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQP 634 P + SP +S PAKP +L A PP P P P P P Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPP-----------PP 2420 Query: 635 TAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQD--------RRESLPTS- 685 PP P SP P+ K +T +A R LP + Sbjct: 2421 PPPPPPLP---PPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTR 2477 Query: 686 ------PPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPP--PMSPSWSERSV 737 PP P S PS L P P S PP+ P P P P+ +++ Sbjct: 2478 ICTTAPPPVPPKPSSIPSGLVFTHRPEP----------SKPPIAPKPVIPQLPTTTQKPT 2527 Query: 738 SPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSP 785 + +P L + + N++ +A K SP S + + SP Sbjct: 2528 -----DIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSP 2570 Score = 33.5 bits (75), Expect = 0.92 Identities = 67/336 (19%), Positives = 110/336 (32%), Gaps = 37/336 (11%) Query: 462 QAKPKPKPNQNLSEASGKGAELYARRQSRME------KYVIESSSHTPELARCPSPTMSL 515 +A P P P ++ S+ + ++ ++ E K ++E T + + P + Sbjct: 1133 KASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTD 1192 Query: 516 PSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLS 575 + A + + P LPE L PE K + +P L Sbjct: 1193 QKQEESKLEKDKASALQEKKP------------LPEEKKLIPEEEKIRSEEKKPLLEEKK 1240 Query: 576 PIKEPAKVSPRAASPA-KPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQP 634 P E K+ P A + A + DL+ + + A P G + L Sbjct: 1241 PTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGL-- 1298 Query: 635 TAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASR 694 P G S + K+ P+P + + +E + T +S+ Sbjct: 1299 -----PSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDT-SSSQ 1352 Query: 695 PPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPP-------MSPSWSERSVSPLRPETEAR 747 P S G G G SS+ P L P S+S+ S SP P A+ Sbjct: 1353 QPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQES-SPSSPSDLAK 1411 Query: 748 PPSRQLQALLAR--NIINAARRKSASPRSAGAENPR 781 S L L A+ + + K P E P+ Sbjct: 1412 LESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPK 1447 Score = 33.1 bits (74), Expect = 1.2 Identities = 36/141 (25%), Positives = 54/141 (38%), Gaps = 18/141 (12%) Query: 659 KQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSM-- 716 K P + + + Q +S SP + S P P P E G S + Sbjct: 3551 KHISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKK----RPTPLEIGYSSHLRA 3606 Query: 717 SSPPPLPPPPPMSPSWSERSVSPLRP----ETEARPPSRQLQALLARNII---NAARRKS 769 S L P PP SP +SPL P E+ P + L ++ + + A+ Sbjct: 3607 DSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPP 3666 Query: 770 ASPRSA-----GAENPRPFSP 785 ASP++A +P+P SP Sbjct: 3667 ASPKTAKMMQRSMSDPKPLSP 3687 Score = 31.6 bits (70), Expect = 3.5 Identities = 32/135 (23%), Positives = 53/135 (39%), Gaps = 15/135 (11%) Query: 488 QSRMEKYVIESSSHTPELARCPSP-TMSLPSSWKYPTNAPGAFRVASR-----------S 535 Q+ +++ + +L SP T SS PT AP ++ S S Sbjct: 3861 QTEFSQFIPPQTQTESQLVPPTSPYTQYQYSSPALPTQAPTSYTQQSHFEQQTLYHQQVS 3920 Query: 536 PARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSS 595 P +T P + ++P PT QP YQL + V I++ + + P S+ Sbjct: 3921 PYQTQPTFQAVATMSFTPQVQPTPTPQPSYQLPSQMMV---IQQKPRQTTLYLEPKITSN 3977 Query: 596 LDLVPNLPKGALPPS 610 +++ N P P S Sbjct: 3978 YEVIRNQPLMIAPVS 3992 >gi|116284398 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 87.8 bits (216), Expect = 4e-17 Identities = 96/345 (27%), Positives = 123/345 (35%), Gaps = 74/345 (21%) Query: 522 PTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPA 581 P + PG F V S PP + P + +P PP P+ P+ Sbjct: 143 PPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPP-----------PV--PS 189 Query: 582 KVSPRAASPAKPSSLDLVPNLPKGALPPSPA-LPRPSRSSPGLYTSPGQDSLQPTAVSPP 640 P +SP S P +P G PSP P P + G G P + S P Sbjct: 190 TPRPIQSSPHNRGS----PPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSP 245 Query: 641 YGGDIS-PVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSL 699 + P +PSRA + P P G RE++P PP ++PP Sbjct: 246 FSNRPPLPPTPSRALDDKPPPPPPP------VGNRPSIHREAVPPPPPQN---NKPPV-- 294 Query: 700 DGWVSPGPWEPGRGSSMSSPPPLPPP-----PPMSPSWSERSVSPLRPETEARPPSRQLQ 754 P P +S +PPP PPP PP+ PS S +P P+ Sbjct: 295 -------PSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQR---------- 337 Query: 755 ALLARNIINAARRKSASPR-SAGAENPRPFSPPRAPPPPP-----------PPPPPPPRM 802 N + S P S G P P PP PPPP PPPPP R Sbjct: 338 --------NLSLSSSTPPLPSPGRSGPLP-PPPSERPPPPVRDPPGRSGPLPPPPPVSRN 388 Query: 803 RSPQPARPGSAAVPGAAFAPIPRS-PLPAGPSSCTSPRSPLPAPP 846 S A P + +P + PRS P P P S +P P PP Sbjct: 389 GSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPP 433 Score = 49.7 bits (117), Expect = 1e-05 Identities = 40/137 (29%), Positives = 54/137 (39%), Gaps = 17/137 (12%) Query: 752 QLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPP--PPPPP-----PPPPPRMRS 804 +L++ R+ + R P + + +PFSPP P P P P PP P R R Sbjct: 110 KLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRM 169 Query: 805 PQPARPGSAAVPGAAFAPIPRSPLP--------AGPSSCTSPRSPLPAP-PRPFLYRRSP 855 P P RP + P + P+P +P P P PR P P P P PF R Sbjct: 170 PPP-RPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGT 228 Query: 856 TDSDVSLDSEDSGAKSP 872 S+ + SP Sbjct: 229 ALGGGSIRQSPLSSSSP 245 Score = 46.2 bits (108), Expect = 1e-04 Identities = 109/483 (22%), Positives = 148/483 (30%), Gaps = 117/483 (24%) Query: 256 RSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNF 315 R P+L A PPS P R P P S P +R M P +P Sbjct: 125 RPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIP 184 Query: 316 TAPPTYTETLSTAPLASWVRSPP-SYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARR 374 P+ + ++P SPP PS P G A G + +S Sbjct: 185 PPVPSTPRPIQSSPHNR--GSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSS 242 Query: 375 GSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEP 434 S F +P + P P + D+K P Sbjct: 243 SS-----PFSNRPPLPPTPS-----RALDDK-------------------------PPPP 267 Query: 435 APRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKY 494 P P+ E VP P + + P+P AS + Sbjct: 268 PPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRP-------SASSQAPPPPPPPSRPGPPP 320 Query: 495 VIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGV 554 + SSS E R P +SL SS P +PG +G Sbjct: 321 LPPSSSGNDETPRLPQRNLSLSSSTP-PLPSPG-----------------------RSGP 356 Query: 555 LRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALP 614 L P P+++PP P+++P P + G LPP P + Sbjct: 357 LPPPPSERPP----------PPVRDP---------PGR-----------SGPLPPPPPVS 386 Query: 615 RPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIE 674 R +S L +P S + V P G P+ P R S A P PS S RN + Sbjct: 387 RNGSTSRALPATPQLPS--RSGVDSPRSGPRPPLPPDRP-SAGAPPPPPPSTSIRNGFQD 443 Query: 675 A--QDRRES---------LPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLP 723 + +D ES LP P+ PS L + G PPLP Sbjct: 444 SPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKL----ARNESRSGSNRRERGAPPLP 499 Query: 724 PPP 726 P P Sbjct: 500 PIP 502 Score = 44.3 bits (103), Expect = 5e-04 Identities = 48/183 (26%), Positives = 65/183 (35%), Gaps = 42/183 (22%) Query: 691 GASRPPSSLDGW--VSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEARP 748 G SRPP G S P+ P G P P P P + P RP+ ++P Sbjct: 122 GGSRPPLLPPGGRSTSAKPFSPPSGPGRF-PVPSPGHRSGPPEPQRNRMPPPRPDVGSKP 180 Query: 749 PSRQLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPA 808 S + + + R +SP + G+ PP P PR SP P Sbjct: 181 DS------IPPPVPSTPRPIQSSPHNRGS----------------PPVPGGPRQPSPGPT 218 Query: 809 RP-----GSAAVPGAAFAPIP---------RSPLPAGPSSCTSPRSPLPAPP---RPFLY 851 P A+ G + P R PLP PS + P P PP RP ++ Sbjct: 219 PPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIH 278 Query: 852 RRS 854 R + Sbjct: 279 REA 281 Score = 32.7 bits (73), Expect = 1.6 Identities = 26/100 (26%), Positives = 41/100 (41%), Gaps = 7/100 (7%) Query: 250 GTSQMERSPMLERRHFGEKAPAPQPPS--LPDRSPRPQRHIMSRSPMVERRMMGQRSPAS 307 G + +SP+ F + P P PS L D+ P P + +R P + R + P + Sbjct: 231 GGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNR-PSIHREAVPPPPPQN 289 Query: 308 ERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSS 347 + P+ + P ++ P S PP L PSS Sbjct: 290 NKPPVPSTPRPSASSQAPPPPPPPSRPGPPP----LPPSS 325 Score = 31.2 bits (69), Expect = 4.5 Identities = 11/22 (50%), Positives = 12/22 (54%) Query: 789 PPPPPPPPPPPPRMRSPQPARP 810 P PPPP PPPPP +P Sbjct: 2 PVPPPPAPPPPPTFALANTEKP 23 Score = 30.4 bits (67), Expect = 7.8 Identities = 28/102 (27%), Positives = 40/102 (39%), Gaps = 17/102 (16%) Query: 50 AQQSSPAPPP------AEVHSPAA--DVNQNLASPSATLTTPTSNSSHNPPATDVNQNPP 101 A P PPP +H A QN P + P+++S PP ++ P Sbjct: 259 ALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGP 318 Query: 102 ATVVPQS--------LPLSSIQQNSSEAQLPSNG-TGPASKP 134 + P S LP ++ +SS LPS G +GP P Sbjct: 319 PPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPP 360 >gi|38373695 WAS/WASL interacting protein family, member 1 [Homo sapiens] Length = 503 Score = 87.8 bits (216), Expect = 4e-17 Identities = 96/345 (27%), Positives = 123/345 (35%), Gaps = 74/345 (21%) Query: 522 PTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPA 581 P + PG F V S PP + P + +P PP P+ P+ Sbjct: 143 PPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIPP-----------PV--PS 189 Query: 582 KVSPRAASPAKPSSLDLVPNLPKGALPPSPA-LPRPSRSSPGLYTSPGQDSLQPTAVSPP 640 P +SP S P +P G PSP P P + G G P + S P Sbjct: 190 TPRPIQSSPHNRGS----PPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSP 245 Query: 641 YGGDIS-PVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSL 699 + P +PSRA + P P G RE++P PP ++PP Sbjct: 246 FSNRPPLPPTPSRALDDKPPPPPPP------VGNRPSIHREAVPPPPPQN---NKPPV-- 294 Query: 700 DGWVSPGPWEPGRGSSMSSPPPLPPP-----PPMSPSWSERSVSPLRPETEARPPSRQLQ 754 P P +S +PPP PPP PP+ PS S +P P+ Sbjct: 295 -------PSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQR---------- 337 Query: 755 ALLARNIINAARRKSASPR-SAGAENPRPFSPPRAPPPPP-----------PPPPPPPRM 802 N + S P S G P P PP PPPP PPPPP R Sbjct: 338 --------NLSLSSSTPPLPSPGRSGPLP-PPPSERPPPPVRDPPGRSGPLPPPPPVSRN 388 Query: 803 RSPQPARPGSAAVPGAAFAPIPRS-PLPAGPSSCTSPRSPLPAPP 846 S A P + +P + PRS P P P S +P P PP Sbjct: 389 GSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPP 433 Score = 49.7 bits (117), Expect = 1e-05 Identities = 40/137 (29%), Positives = 54/137 (39%), Gaps = 17/137 (12%) Query: 752 QLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPP--PPPPP-----PPPPPRMRS 804 +L++ R+ + R P + + +PFSPP P P P P PP P R R Sbjct: 110 KLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRM 169 Query: 805 PQPARPGSAAVPGAAFAPIPRSPLP--------AGPSSCTSPRSPLPAP-PRPFLYRRSP 855 P P RP + P + P+P +P P P PR P P P P PF R Sbjct: 170 PPP-RPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPPFPGNRGT 228 Query: 856 TDSDVSLDSEDSGAKSP 872 S+ + SP Sbjct: 229 ALGGGSIRQSPLSSSSP 245 Score = 46.2 bits (108), Expect = 1e-04 Identities = 109/483 (22%), Positives = 148/483 (30%), Gaps = 117/483 (24%) Query: 256 RSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNF 315 R P+L A PPS P R P P S P +R M P +P Sbjct: 125 RPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDVGSKPDSIP 184 Query: 316 TAPPTYTETLSTAPLASWVRSPP-SYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARR 374 P+ + ++P SPP PS P G A G + +S Sbjct: 185 PPVPSTPRPIQSSPHNR--GSPPVPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSS 242 Query: 375 GSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEP 434 S F +P + P P + D+K P Sbjct: 243 SS-----PFSNRPPLPPTPS-----RALDDK-------------------------PPPP 267 Query: 435 APRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKY 494 P P+ E VP P + + P+P AS + Sbjct: 268 PPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRP-------SASSQAPPPPPPPSRPGPPP 320 Query: 495 VIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGV 554 + SSS E R P +SL SS P +PG +G Sbjct: 321 LPPSSSGNDETPRLPQRNLSLSSSTP-PLPSPG-----------------------RSGP 356 Query: 555 LRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALP 614 L P P+++PP P+++P P + G LPP P + Sbjct: 357 LPPPPSERPP----------PPVRDP---------PGR-----------SGPLPPPPPVS 386 Query: 615 RPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIE 674 R +S L +P S + V P G P+ P R S A P PS S RN + Sbjct: 387 RNGSTSRALPATPQLPS--RSGVDSPRSGPRPPLPPDRP-SAGAPPPPPPSTSIRNGFQD 443 Query: 675 A--QDRRES---------LPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLP 723 + +D ES LP P+ PS L + G PPLP Sbjct: 444 SPCEDEWESRFYFHPISDLPPPEPYVQTTKSYPSKL----ARNESRSGSNRRERGAPPLP 499 Query: 724 PPP 726 P P Sbjct: 500 PIP 502 Score = 44.3 bits (103), Expect = 5e-04 Identities = 48/183 (26%), Positives = 65/183 (35%), Gaps = 42/183 (22%) Query: 691 GASRPPSSLDGW--VSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEARP 748 G SRPP G S P+ P G P P P P + P RP+ ++P Sbjct: 122 GGSRPPLLPPGGRSTSAKPFSPPSGPGRF-PVPSPGHRSGPPEPQRNRMPPPRPDVGSKP 180 Query: 749 PSRQLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPA 808 S + + + R +SP + G+ PP P PR SP P Sbjct: 181 DS------IPPPVPSTPRPIQSSPHNRGS----------------PPVPGGPRQPSPGPT 218 Query: 809 RP-----GSAAVPGAAFAPIP---------RSPLPAGPSSCTSPRSPLPAPP---RPFLY 851 P A+ G + P R PLP PS + P P PP RP ++ Sbjct: 219 PPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIH 278 Query: 852 RRS 854 R + Sbjct: 279 REA 281 Score = 32.7 bits (73), Expect = 1.6 Identities = 26/100 (26%), Positives = 41/100 (41%), Gaps = 7/100 (7%) Query: 250 GTSQMERSPMLERRHFGEKAPAPQPPS--LPDRSPRPQRHIMSRSPMVERRMMGQRSPAS 307 G + +SP+ F + P P PS L D+ P P + +R P + R + P + Sbjct: 231 GGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNR-PSIHREAVPPPPPQN 289 Query: 308 ERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSS 347 + P+ + P ++ P S PP L PSS Sbjct: 290 NKPPVPSTPRPSASSQAPPPPPPPSRPGPPP----LPPSS 325 Score = 31.2 bits (69), Expect = 4.5 Identities = 11/22 (50%), Positives = 12/22 (54%) Query: 789 PPPPPPPPPPPPRMRSPQPARP 810 P PPPP PPPPP +P Sbjct: 2 PVPPPPAPPPPPTFALANTEKP 23 Score = 30.4 bits (67), Expect = 7.8 Identities = 28/102 (27%), Positives = 40/102 (39%), Gaps = 17/102 (16%) Query: 50 AQQSSPAPPP------AEVHSPAA--DVNQNLASPSATLTTPTSNSSHNPPATDVNQNPP 101 A P PPP +H A QN P + P+++S PP ++ P Sbjct: 259 ALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGP 318 Query: 102 ATVVPQS--------LPLSSIQQNSSEAQLPSNG-TGPASKP 134 + P S LP ++ +SS LPS G +GP P Sbjct: 319 PPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPP 360 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 87.0 bits (214), Expect = 7e-17 Identities = 106/482 (21%), Positives = 183/482 (37%), Gaps = 60/482 (12%) Query: 386 KPKVTPNPDLL-DLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAA 444 +P + PN D + T +++ + ++ G E + +E ++ S Sbjct: 127 RPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTS--- 183 Query: 445 AEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPE 504 A+++ P + ++ AKP PK +E + KG L ++ E +S TP+ Sbjct: 184 AKDLAP-------TSKVLAKPTPK-----AETTTKGPALTTPKEPTPTTPK-EPASTTPK 230 Query: 505 LARCPSPTM--SLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQ 562 P+PT S P++ K P AP + A +P P + P TK+ Sbjct: 231 E---PTPTTIKSAPTTPKEP--APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE 285 Query: 563 PPYQLRPSLFVLSPI--KEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSS 620 P P+ +P KEPA +P+ +P P + P PK P +P P P+ Sbjct: 286 PA----PTTTKSAPTTPKEPAPTTPKKPAPTTPK--EPAPTTPKEPTPTTPKEPAPTTKE 339 Query: 621 PGLYTSPGQDSLQPTAVSPPYGGDISPVSP-------SRAWSPRAKQAPRPSFSTRNAGI 673 P T P +P + +P +P ++ SP + P P+ +T++A Sbjct: 340 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT-TTKSAPT 398 Query: 674 EAQDRRESLPTSPPWTPGASRPPSSLDGWVS----PGPWEPGRGSSMSSPPPLPPPPPMS 729 ++ + S P TP P ++ + + P P P + + + P P P Sbjct: 399 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 458 Query: 730 PSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSP---- 785 + + +P P+ A ++ + + K A E P P +P Sbjct: 459 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP---EKPAPTTPEELA 515 Query: 786 PRAPPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAP 845 P P P P P P +P+ A P + P P+ P P T+P+ P P Sbjct: 516 PTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT---TPKEPAP------TTPKEPAPTT 566 Query: 846 PR 847 P+ Sbjct: 567 PK 568 Score = 81.3 bits (199), Expect = 4e-15 Identities = 98/470 (20%), Positives = 163/470 (34%), Gaps = 53/470 (11%) Query: 432 QEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKP------KPKPNQNLSEASGKGAELYA 485 +EPAP PA P + +P +P KP P A E Sbjct: 268 KEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTP 327 Query: 486 RRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLY 545 E + TP+ +P P++ K P AP + + + + P + Sbjct: 328 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP--APTTPKEPAPTTTKEPSPTTP 385 Query: 546 HGYLPENGVLRPEPTKQPPYQLRPSLFVL------SPIKEPAKVSPRAASPAKPSSLDLV 599 P P TK+P S + KEPA +P+ +P P Sbjct: 386 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKP--A 443 Query: 600 PNLPKGALPPSPALPRPSRSSPGLYTSPGQDS-LQPTAVSPPYGGDISPVSPSRAWSPRA 658 P PK P +P P P+ + T+P + + P +P ++P +P + +P Sbjct: 444 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL-APTT 502 Query: 659 KQAPRPSFSTRNAGIEAQDRRESLPTSP-PWTPGASRPPSSLDGWVSPGPWEPGRGSSMS 717 + P P+ A ++ + P P P TP A+ P + + P P P + + Sbjct: 503 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE----PAPTTPKEPAPTT 558 Query: 718 SPPPLPPPPPMSPSWSERSVSPLR-----PETEARPPSRQLQALLARNIINAARRKSA-- 770 P P P + + + +P P T +P ++L + + K A Sbjct: 559 PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 618 Query: 771 SPRSAGAENPRPFSP--PRAPPPPPP---------------PPPPPPRMRSPQPARPGSA 813 +P+ P+ +P P+ P P P P P P+ +P + ++ Sbjct: 619 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTS 678 Query: 814 AVPGAAFAPIPRSPLPAGPS--SCTSPRSPLPAPPRPFLYRRSPTDSDVS 861 P+ P P + T+P+ P P P PT S+VS Sbjct: 679 TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPE----TPPPTTSEVS 724 Score = 79.3 bits (194), Expect = 1e-14 Identities = 159/772 (20%), Positives = 246/772 (31%), Gaps = 77/772 (9%) Query: 46 QNREAQQSSPAPPPAEVHSPAADVNQNLASPSATLTTP-TSNSSHNPPATDVNQNPPATV 104 +NR ++ +P PP + + L + +TTP TS + HN +T + Sbjct: 71 KNRTKKKPTPKPPVVD------EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPI 124 Query: 105 VPQ-SLPLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTP 163 P+ SLP +S S E L N T + Q +E +T + S Sbjct: 125 NPRPSLPPNS--DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEK--TTSAKETQSIE 180 Query: 164 ATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYS 223 T+ + + ++ P A L + T + + S TPT + S Sbjct: 181 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPT-PTTPKEPASTTPKEPTPTTIKS 239 Query: 224 EVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPR 283 T K P+ + P + P T+ E +P K PAP P + Sbjct: 240 AP--TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT------PKEPAPTTTKEPAPTTT 291 Query: 284 PQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVL 343 + P +P + ++P AP T E T P +P + Sbjct: 292 KSAPTTPKEP----------APTTPKKP-----APTTPKEPAPTTPKEPTPTTPKEPAPT 336 Query: 344 YPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVT----PNPDLLDLV 399 P + P + A ++ T ++P T P P Sbjct: 337 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 396 Query: 400 QTADEK---RRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCL 456 T ++ + E P A +EPAP PA P + Sbjct: 397 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA-PTTP 455 Query: 457 KSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIES-SSHTPELARCPSPTMSL 515 K P KP P A E ++ E + TPE +P Sbjct: 456 KEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA 515 Query: 516 PSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLS 575 P++ + PT PA T P + N P PT P + P+ + Sbjct: 516 PTTPEEPT------PTTPEEPAPTTPKA-----AAPNTPKEPAPT--TPKEPAPT----T 558 Query: 576 PIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPT 635 P KEPA +P+ +P P P K P +P P P +P P + Sbjct: 559 P-KEPAPTTPKETAPTTPKG--TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 615 Query: 636 AVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRP 695 A + P G +P +P +P + P P T G +E PT+P Sbjct: 616 APTTPKG--TAPTTPKEP-APTTPKEPAP---TTPKGTAPTTLKEPAPTTPKKPAPKELA 669 Query: 696 PSSLDGWVSPGPWEPGRGSSMSSPPPLP-PPPPMSPSWSERSVSPLRPETEARPPSRQLQ 754 P++ G S +P + + P P P P +P + +P PET S Sbjct: 670 PTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP----KKPAPTTPETPPPTTSEVST 725 Query: 755 ALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQ 806 + + S AE P P + +P P P P P+ Sbjct: 726 PTTTKEPTTIHKSPDESTPELSAE-PTPKALENSPKEPGVPTTKTPAATKPE 776 Score = 73.9 bits (180), Expect = 6e-13 Identities = 98/482 (20%), Positives = 155/482 (32%), Gaps = 50/482 (10%) Query: 386 KPKVTPNPDLLD-----------LVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEP 434 K K TP P ++D V T D Q ++ V P A+ N + Sbjct: 75 KKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNK----VSTSPKITTAKPINPRPSL 130 Query: 435 APRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKY 494 P S + V K ++ K N+ S GK A+ +EK Sbjct: 131 PPNSDTSKETSLTVN-------KETTVETKETTTTNKQTS-TDGKEKTTSAKETQSIEKT 182 Query: 495 VIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGV 554 + + T ++ P+P + T + PA T P + Sbjct: 183 SAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPT 242 Query: 555 L--RPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAK-----PSSLDLVPNLPKGAL 607 P PT P + KEPA +P+ +P P++ P PK Sbjct: 243 TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA 302 Query: 608 PPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFS 667 P +P P P+ T+P + PT +P P ++ +P + P P+ Sbjct: 303 PTTPKKPAPTTPKEPAPTTPKE----PTPTTPK-----EPAPTTKEPAPTTPKEPAPTAP 353 Query: 668 TRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPP 727 + A ++ + P P P ++ PS P EP ++ S+P P P Sbjct: 354 KKPAPTTPKEPAPTTPKEP--APTTTKEPSPTT------PKEPAPTTTKSAPTTTKEPAP 405 Query: 728 MSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSPPR 787 + + + P T P + A P + P P + + Sbjct: 406 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 465 Query: 788 -APPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSC--TSPRSPLPA 844 AP P P P P+ +P + + P P P P P T+P P P Sbjct: 466 PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPT 525 Query: 845 PP 846 P Sbjct: 526 TP 527 Score = 68.2 bits (165), Expect = 3e-11 Identities = 171/866 (19%), Positives = 272/866 (31%), Gaps = 120/866 (13%) Query: 5 SEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQNREAQQSSPAPPPAEVHS 64 S+E SL + E +E + T + + AP + Sbjct: 137 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 196 Query: 65 PAADVNQNLASPSATLTT-PTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQNSSEAQL 123 P P+ T PT + P +T + P T+ +S P + + + Sbjct: 197 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI--KSAPTTP--KEPAPTTT 252 Query: 124 PSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTS--TFSREATLIPSSR 181 S T P T + P P E +T K P TT S T +E + Sbjct: 253 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT----KEPAPTTTKSAPTTPKEPAPTTPKK 308 Query: 182 PPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLAKPPSVVNRTAR 241 P + + +P + A TTP + KP + Sbjct: 309 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP---KKPAPTTPKEPA 365 Query: 242 PFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPP-SLPDRSPRPQRHIMSRSPMVERRMM 300 P + P T+ E SP K PAP S P + P +P + Sbjct: 366 PTTPKEPAPTTTKEPSPTTP------KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK--- 416 Query: 301 GQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSSD----PKSSHLKG 356 + SP + + P P T AP +P + P++ P + Sbjct: 417 -EPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 475 Query: 357 QAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGV 416 P + + K T EKP T +L T +E + Sbjct: 476 PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT--TPEEPTPTTPE----- 528 Query: 417 EEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEA 476 E P A A N +EPAP PA P +P P + + Sbjct: 529 EPAPTTPKAAAPNTPKEPAPTTPKEPA---------------PTTPKEPAPTTPKETAPT 573 Query: 477 SGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSP 536 + KG ++ P + P+P P++ K PT+ P Sbjct: 574 TPKGTAPTTLKEP------------APTTPKKPAPKELAPTTTKEPTST------TCDKP 615 Query: 537 ARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSL 596 A T P G P T + P P + +KEPA +P+ KP+ Sbjct: 616 APTTPK----GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK-----KPAPK 666 Query: 597 DLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSP 656 +L P KG P S +P+ ++P PT P +P +P + +P Sbjct: 667 ELAPTTTKG--PTSTTSDKPAPTTP--------KETAPTTPKEP-----APTTPKKP-AP 710 Query: 657 RAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGW---VSPGPWEPGRG 713 + P P+ S + ++ PT+ +P S P S + + P EPG Sbjct: 711 TTPETPPPTTSEVSTPTTTKE-----PTTIHKSPDESTPELSAEPTPKALENSPKEPGVP 765 Query: 714 SSMSSPPPLPPPPPMSPSWSERSVS-PLR--PETEARPP--SRQLQALLARNIINAARRK 768 ++ + P P M+ + +++ LR PET P +++ + + Sbjct: 766 TTKT---PAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITAT 822 Query: 769 SASPRSAGAENPRPFSPPRAPPPPPPPPPPPPR--------MRSP-QPARPGSAAVPGAA 819 + S ++ PF P + M P + A+P A A Sbjct: 823 TTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKA 882 Query: 820 FAPIPRSPLPAGPSSCTSPRSPLPAP 845 P P+ P A P TS + P P Sbjct: 883 TTPKPQKPTKA-PKKPTSTKKPKTMP 907 Score = 49.3 bits (116), Expect = 2e-05 Identities = 45/205 (21%), Positives = 65/205 (31%), Gaps = 13/205 (6%) Query: 662 PRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGS--SMSSP 719 P P T G +E PT+P P ++ P + P P + + S Sbjct: 197 PTPKAETTTKGPALTTPKEPTPTTPK-EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 255 Query: 720 PPLPPPPPMSPSWSERSVSPLRPE-TEARPPSRQLQALLARNIINAARRKSASPRSAGAE 778 P P P + + +P P T + P+ A P + Sbjct: 256 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 315 Query: 779 NPRPFSPPRAPPPPPPPPPPPPRMRSPQPARPGSAA--VPGAAFAPIPRSPLPA-----G 831 P P +P P P P P P + P P P A P P+ P P Sbjct: 316 EPAPTTPKE--PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 373 Query: 832 PSSCTSPRSPLPAPPRPFLYRRSPT 856 P++ P P P P + +PT Sbjct: 374 PTTTKEPSPTTPKEPAPTTTKSAPT 398 Score = 39.3 bits (90), Expect = 0.017 Identities = 46/251 (18%), Positives = 86/251 (34%), Gaps = 17/251 (6%) Query: 609 PSPALPRPSRSSPGL------YTSPGQDSLQPTAVSP-PYGGDISPVSPSRAWSPRAKQA 661 P+P P + GL T+P + Q VS P P++P + P + + Sbjct: 78 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 137 Query: 662 PRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGW----VSPGPWEPGRGSSMS 717 S T N + + + T G + S+ + S P ++ Sbjct: 138 KETSL-TVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAP-TSKVLA 195 Query: 718 SPPPLPPPPPMSPSWSE-RSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAG 776 P P P+ + + +P P+ A ++ ++ + + + + Sbjct: 196 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 255 Query: 777 AENPRPFSPPRAPPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCT 836 P+ +P P P P P + +PA + + P P P +P P T Sbjct: 256 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAP---T 312 Query: 837 SPRSPLPAPPR 847 +P+ P P P+ Sbjct: 313 TPKEPAPTTPK 323 Score = 38.9 bits (89), Expect = 0.022 Identities = 108/569 (18%), Positives = 183/569 (32%), Gaps = 116/569 (20%) Query: 50 AQQSSPAPPPAEVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSL 109 A ++ P P PA + A + TPT+ P + PA P+ L Sbjct: 459 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE----KPAPTTPEEL 514 Query: 110 -PLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTS 168 P + + + + P+ T A+ P+T P+ PA +TP Sbjct: 515 APTTPEEPTPTTPEEPAPTTPKAAAPNT------PKEPAP------------TTPKEPAP 556 Query: 169 TFSREA--TLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVH 226 T +E T + P + + L + P T A +E++ PT Sbjct: 557 TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA-------PTTTKEPTS 609 Query: 227 FTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGE--KAPAPQPPSLPDRSPRP 284 T KP + P + P T+ E +P + K PAP P + P P Sbjct: 610 TTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP----KKPAP 665 Query: 285 QRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLY 344 + + G S S++ AP T ET T P +P + Sbjct: 666 KE-------LAPTTTKGPTSTTSDK------PAPTTPKETAPTTPKEPAPTTPKKPAPTT 712 Query: 345 PSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADE 404 P + P ++ + V P T P T Sbjct: 713 PETPPPTT-----------------------------SEVSTPTTTKEP-------TTIH 736 Query: 405 KRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAK 464 K E+ E P AL N +EP +PAA + PE + K + Sbjct: 737 KSPDESTPELSAEPTPKAL----ENSPKEPGVPTTKTPAATK---PEMTTTAKDKTTERD 789 Query: 465 PKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTN 524 + P + +M K ++ T E ++ + T + S+ T Sbjct: 790 LRTTPETTTAAP-------------KMTKETATTTEKTTE-SKITATTTQVTSTTTQDTT 835 Query: 525 APGAFRVAS-RSPARTPPASLYHGYLPENGVL-RPEPTKQPPYQLRPSLFVLSPIKEPAK 582 F++ + ++ P + + ++ +PE T +P + S ++P K Sbjct: 836 P---FKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK 892 Query: 583 VSPRAASPAKPSSLDLVPNLPKGALPPSP 611 + S KP ++ P + K P+P Sbjct: 893 APKKPTSTKKPKTM---PRVRKPKTTPTP 918 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 87.0 bits (214), Expect = 7e-17 Identities = 106/482 (21%), Positives = 183/482 (37%), Gaps = 60/482 (12%) Query: 386 KPKVTPNPDLL-DLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAA 444 +P + PN D + T +++ + ++ G E + +E ++ S Sbjct: 168 RPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTS--- 224 Query: 445 AEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPE 504 A+++ P + ++ AKP PK +E + KG L ++ E +S TP+ Sbjct: 225 AKDLAP-------TSKVLAKPTPK-----AETTTKGPALTTPKEPTPTTPK-EPASTTPK 271 Query: 505 LARCPSPTM--SLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQ 562 P+PT S P++ K P AP + A +P P + P TK+ Sbjct: 272 E---PTPTTIKSAPTTPKEP--APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE 326 Query: 563 PPYQLRPSLFVLSPI--KEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSS 620 P P+ +P KEPA +P+ +P P + P PK P +P P P+ Sbjct: 327 PA----PTTTKSAPTTPKEPAPTTPKKPAPTTPK--EPAPTTPKEPTPTTPKEPAPTTKE 380 Query: 621 PGLYTSPGQDSLQPTAVSPPYGGDISPVSP-------SRAWSPRAKQAPRPSFSTRNAGI 673 P T P +P + +P +P ++ SP + P P+ +T++A Sbjct: 381 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT-TTKSAPT 439 Query: 674 EAQDRRESLPTSPPWTPGASRPPSSLDGWVS----PGPWEPGRGSSMSSPPPLPPPPPMS 729 ++ + S P TP P ++ + + P P P + + + P P P Sbjct: 440 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 499 Query: 730 PSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSP---- 785 + + +P P+ A ++ + + K A E P P +P Sbjct: 500 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP---EKPAPTTPEELA 556 Query: 786 PRAPPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAP 845 P P P P P P +P+ A P + P P+ P P T+P+ P P Sbjct: 557 PTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT---TPKEPAP------TTPKEPAPTT 607 Query: 846 PR 847 P+ Sbjct: 608 PK 609 Score = 81.3 bits (199), Expect = 4e-15 Identities = 98/470 (20%), Positives = 163/470 (34%), Gaps = 53/470 (11%) Query: 432 QEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKP------KPKPNQNLSEASGKGAELYA 485 +EPAP PA P + +P +P KP P A E Sbjct: 309 KEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTP 368 Query: 486 RRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLY 545 E + TP+ +P P++ K P AP + + + + P + Sbjct: 369 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEP--APTTPKEPAPTTTKEPSPTTP 426 Query: 546 HGYLPENGVLRPEPTKQPPYQLRPSLFVL------SPIKEPAKVSPRAASPAKPSSLDLV 599 P P TK+P S + KEPA +P+ +P P Sbjct: 427 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKP--A 484 Query: 600 PNLPKGALPPSPALPRPSRSSPGLYTSPGQDS-LQPTAVSPPYGGDISPVSPSRAWSPRA 658 P PK P +P P P+ + T+P + + P +P ++P +P + +P Sbjct: 485 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKL-APTT 543 Query: 659 KQAPRPSFSTRNAGIEAQDRRESLPTSP-PWTPGASRPPSSLDGWVSPGPWEPGRGSSMS 717 + P P+ A ++ + P P P TP A+ P + + P P P + + Sbjct: 544 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE----PAPTTPKEPAPTT 599 Query: 718 SPPPLPPPPPMSPSWSERSVSPLR-----PETEARPPSRQLQALLARNIINAARRKSA-- 770 P P P + + + +P P T +P ++L + + K A Sbjct: 600 PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 659 Query: 771 SPRSAGAENPRPFSP--PRAPPPPPP---------------PPPPPPRMRSPQPARPGSA 813 +P+ P+ +P P+ P P P P P P+ +P + ++ Sbjct: 660 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTS 719 Query: 814 AVPGAAFAPIPRSPLPAGPS--SCTSPRSPLPAPPRPFLYRRSPTDSDVS 861 P+ P P + T+P+ P P P PT S+VS Sbjct: 720 TTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPE----TPPPTTSEVS 765 Score = 79.3 bits (194), Expect = 1e-14 Identities = 159/772 (20%), Positives = 246/772 (31%), Gaps = 77/772 (9%) Query: 46 QNREAQQSSPAPPPAEVHSPAADVNQNLASPSATLTTP-TSNSSHNPPATDVNQNPPATV 104 +NR ++ +P PP + + L + +TTP TS + HN +T + Sbjct: 112 KNRTKKKPTPKPPVVD------EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPI 165 Query: 105 VPQ-SLPLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTP 163 P+ SLP +S S E L N T + Q +E +T + S Sbjct: 166 NPRPSLPPNS--DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEK--TTSAKETQSIE 221 Query: 164 ATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYS 223 T+ + + ++ P A L + T + + S TPT + S Sbjct: 222 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPT-PTTPKEPASTTPKEPTPTTIKS 280 Query: 224 EVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPR 283 T K P+ + P + P T+ E +P K PAP P + Sbjct: 281 AP--TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT------PKEPAPTTTKEPAPTTT 332 Query: 284 PQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVL 343 + P +P + ++P AP T E T P +P + Sbjct: 333 KSAPTTPKEP----------APTTPKKP-----APTTPKEPAPTTPKEPTPTTPKEPAPT 377 Query: 344 YPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVT----PNPDLLDLV 399 P + P + A ++ T ++P T P P Sbjct: 378 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 437 Query: 400 QTADEK---RRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCL 456 T ++ + E P A +EPAP PA P + Sbjct: 438 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA-PTTP 496 Query: 457 KSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIES-SSHTPELARCPSPTMSL 515 K P KP P A E ++ E + TPE +P Sbjct: 497 KEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA 556 Query: 516 PSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLS 575 P++ + PT PA T P + N P PT P + P+ + Sbjct: 557 PTTPEEPT------PTTPEEPAPTTPKA-----AAPNTPKEPAPT--TPKEPAPT----T 599 Query: 576 PIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPT 635 P KEPA +P+ +P P P K P +P P P +P P + Sbjct: 600 P-KEPAPTTPKETAPTTPKG--TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 656 Query: 636 AVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRP 695 A + P G +P +P +P + P P T G +E PT+P Sbjct: 657 APTTPKG--TAPTTPKEP-APTTPKEPAP---TTPKGTAPTTLKEPAPTTPKKPAPKELA 710 Query: 696 PSSLDGWVSPGPWEPGRGSSMSSPPPLP-PPPPMSPSWSERSVSPLRPETEARPPSRQLQ 754 P++ G S +P + + P P P P +P + +P PET S Sbjct: 711 PTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP----KKPAPTTPETPPPTTSEVST 766 Query: 755 ALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQ 806 + + S AE P P + +P P P P P+ Sbjct: 767 PTTTKEPTTIHKSPDESTPELSAE-PTPKALENSPKEPGVPTTKTPAATKPE 817 Score = 73.9 bits (180), Expect = 6e-13 Identities = 98/482 (20%), Positives = 155/482 (32%), Gaps = 50/482 (10%) Query: 386 KPKVTPNPDLLD-----------LVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEP 434 K K TP P ++D V T D Q ++ V P A+ N + Sbjct: 116 KKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNK----VSTSPKITTAKPINPRPSL 171 Query: 435 APRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKY 494 P S + V K ++ K N+ S GK A+ +EK Sbjct: 172 PPNSDTSKETSLTVN-------KETTVETKETTTTNKQTS-TDGKEKTTSAKETQSIEKT 223 Query: 495 VIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGV 554 + + T ++ P+P + T + PA T P + Sbjct: 224 SAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPT 283 Query: 555 L--RPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAK-----PSSLDLVPNLPKGAL 607 P PT P + KEPA +P+ +P P++ P PK Sbjct: 284 TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA 343 Query: 608 PPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFS 667 P +P P P+ T+P + PT +P P ++ +P + P P+ Sbjct: 344 PTTPKKPAPTTPKEPAPTTPKE----PTPTTPK-----EPAPTTKEPAPTTPKEPAPTAP 394 Query: 668 TRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPP 727 + A ++ + P P P ++ PS P EP ++ S+P P P Sbjct: 395 KKPAPTTPKEPAPTTPKEP--APTTTKEPSPTT------PKEPAPTTTKSAPTTTKEPAP 446 Query: 728 MSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSPPR 787 + + + P T P + A P + P P + + Sbjct: 447 TTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKK 506 Query: 788 -APPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSC--TSPRSPLPA 844 AP P P P P+ +P + + P P P P P T+P P P Sbjct: 507 PAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPT 566 Query: 845 PP 846 P Sbjct: 567 TP 568 Score = 68.2 bits (165), Expect = 3e-11 Identities = 171/866 (19%), Positives = 272/866 (31%), Gaps = 120/866 (13%) Query: 5 SEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQNREAQQSSPAPPPAEVHS 64 S+E SL + E +E + T + + AP + Sbjct: 178 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 237 Query: 65 PAADVNQNLASPSATLTT-PTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQNSSEAQL 123 P P+ T PT + P +T + P T+ +S P + + + Sbjct: 238 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI--KSAPTTP--KEPAPTTT 293 Query: 124 PSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTS--TFSREATLIPSSR 181 S T P T + P P E +T K P TT S T +E + Sbjct: 294 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT----KEPAPTTTKSAPTTPKEPAPTTPKK 349 Query: 182 PPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLAKPPSVVNRTAR 241 P + + +P + A TTP + KP + Sbjct: 350 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP---KKPAPTTPKEPA 406 Query: 242 PFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPP-SLPDRSPRPQRHIMSRSPMVERRMM 300 P + P T+ E SP K PAP S P + P +P + Sbjct: 407 PTTPKEPAPTTTKEPSPTTP------KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK--- 457 Query: 301 GQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSSD----PKSSHLKG 356 + SP + + P P T AP +P + P++ P + Sbjct: 458 -EPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 516 Query: 357 QAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGV 416 P + + K T EKP T +L T +E + Sbjct: 517 PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT--TPEEPTPTTPE----- 569 Query: 417 EEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEA 476 E P A A N +EPAP PA P +P P + + Sbjct: 570 EPAPTTPKAAAPNTPKEPAPTTPKEPA---------------PTTPKEPAPTTPKETAPT 614 Query: 477 SGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSP 536 + KG ++ P + P+P P++ K PT+ P Sbjct: 615 TPKGTAPTTLKEP------------APTTPKKPAPKELAPTTTKEPTST------TCDKP 656 Query: 537 ARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSL 596 A T P G P T + P P + +KEPA +P+ KP+ Sbjct: 657 APTTPK----GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK-----KPAPK 707 Query: 597 DLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSP 656 +L P KG P S +P+ ++P PT P +P +P + +P Sbjct: 708 ELAPTTTKG--PTSTTSDKPAPTTP--------KETAPTTPKEP-----APTTPKKP-AP 751 Query: 657 RAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGW---VSPGPWEPGRG 713 + P P+ S + ++ PT+ +P S P S + + P EPG Sbjct: 752 TTPETPPPTTSEVSTPTTTKE-----PTTIHKSPDESTPELSAEPTPKALENSPKEPGVP 806 Query: 714 SSMSSPPPLPPPPPMSPSWSERSVS-PLR--PETEARPP--SRQLQALLARNIINAARRK 768 ++ + P P M+ + +++ LR PET P +++ + + Sbjct: 807 TTKT---PAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITAT 863 Query: 769 SASPRSAGAENPRPFSPPRAPPPPPPPPPPPPR--------MRSP-QPARPGSAAVPGAA 819 + S ++ PF P + M P + A+P A A Sbjct: 864 TTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKA 923 Query: 820 FAPIPRSPLPAGPSSCTSPRSPLPAP 845 P P+ P A P TS + P P Sbjct: 924 TTPKPQKPTKA-PKKPTSTKKPKTMP 948 Score = 49.3 bits (116), Expect = 2e-05 Identities = 45/205 (21%), Positives = 65/205 (31%), Gaps = 13/205 (6%) Query: 662 PRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGS--SMSSP 719 P P T G +E PT+P P ++ P + P P + + S Sbjct: 238 PTPKAETTTKGPALTTPKEPTPTTPK-EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 296 Query: 720 PPLPPPPPMSPSWSERSVSPLRPE-TEARPPSRQLQALLARNIINAARRKSASPRSAGAE 778 P P P + + +P P T + P+ A P + Sbjct: 297 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 356 Query: 779 NPRPFSPPRAPPPPPPPPPPPPRMRSPQPARPGSAA--VPGAAFAPIPRSPLPA-----G 831 P P +P P P P P P + P P P A P P+ P P Sbjct: 357 EPAPTTPKE--PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 414 Query: 832 PSSCTSPRSPLPAPPRPFLYRRSPT 856 P++ P P P P + +PT Sbjct: 415 PTTTKEPSPTTPKEPAPTTTKSAPT 439 Score = 39.3 bits (90), Expect = 0.017 Identities = 46/251 (18%), Positives = 86/251 (34%), Gaps = 17/251 (6%) Query: 609 PSPALPRPSRSSPGL------YTSPGQDSLQPTAVSP-PYGGDISPVSPSRAWSPRAKQA 661 P+P P + GL T+P + Q VS P P++P + P + + Sbjct: 119 PTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTS 178 Query: 662 PRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGW----VSPGPWEPGRGSSMS 717 S T N + + + T G + S+ + S P ++ Sbjct: 179 KETSL-TVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAP-TSKVLA 236 Query: 718 SPPPLPPPPPMSPSWSE-RSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAG 776 P P P+ + + +P P+ A ++ ++ + + + + Sbjct: 237 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA 296 Query: 777 AENPRPFSPPRAPPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCT 836 P+ +P P P P P + +PA + + P P P +P P T Sbjct: 297 PTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAP---T 353 Query: 837 SPRSPLPAPPR 847 +P+ P P P+ Sbjct: 354 TPKEPAPTTPK 364 Score = 38.9 bits (89), Expect = 0.022 Identities = 108/569 (18%), Positives = 183/569 (32%), Gaps = 116/569 (20%) Query: 50 AQQSSPAPPPAEVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSL 109 A ++ P P PA + A + TPT+ P + PA P+ L Sbjct: 500 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE----KPAPTTPEEL 555 Query: 110 -PLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTS 168 P + + + + P+ T A+ P+T P+ PA +TP Sbjct: 556 APTTPEEPTPTTPEEPAPTTPKAAAPNT------PKEPAP------------TTPKEPAP 597 Query: 169 TFSREA--TLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVH 226 T +E T + P + + L + P T A +E++ PT Sbjct: 598 TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA-------PTTTKEPTS 650 Query: 227 FTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGE--KAPAPQPPSLPDRSPRP 284 T KP + P + P T+ E +P + K PAP P + P P Sbjct: 651 TTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP----KKPAP 706 Query: 285 QRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLY 344 + + G S S++ AP T ET T P +P + Sbjct: 707 KE-------LAPTTTKGPTSTTSDK------PAPTTPKETAPTTPKEPAPTTPKKPAPTT 753 Query: 345 PSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADE 404 P + P ++ + V P T P T Sbjct: 754 PETPPPTT-----------------------------SEVSTPTTTKEP-------TTIH 777 Query: 405 KRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAK 464 K E+ E P AL N +EP +PAA + PE + K + Sbjct: 778 KSPDESTPELSAEPTPKAL----ENSPKEPGVPTTKTPAATK---PEMTTTAKDKTTERD 830 Query: 465 PKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTN 524 + P + +M K ++ T E ++ + T + S+ T Sbjct: 831 LRTTPETTTAAP-------------KMTKETATTTEKTTE-SKITATTTQVTSTTTQDTT 876 Query: 525 APGAFRVAS-RSPARTPPASLYHGYLPENGVL-RPEPTKQPPYQLRPSLFVLSPIKEPAK 582 F++ + ++ P + + ++ +PE T +P + S ++P K Sbjct: 877 P---FKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK 933 Query: 583 VSPRAASPAKPSSLDLVPNLPKGALPPSP 611 + S KP ++ P + K P+P Sbjct: 934 APKKPTSTKKPKTM---PRVRKPKTTPTP 959 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 87.0 bits (214), Expect = 7e-17 Identities = 106/482 (21%), Positives = 183/482 (37%), Gaps = 60/482 (12%) Query: 386 KPKVTPNPDLL-DLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAA 444 +P + PN D + T +++ + ++ G E + +E ++ S Sbjct: 220 RPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTS--- 276 Query: 445 AEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPE 504 A+++ P + ++ AKP PK +E + KG L ++ E +S TP+ Sbjct: 277 AKDLAP-------TSKVLAKPTPK-----AETTTKGPALTTPKEPTPTTPK-EPASTTPK 323 Query: 505 LARCPSPTM--SLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQ 562 P+PT S P++ K P AP + A +P P + P TK+ Sbjct: 324 E---PTPTTIKSAPTTPKEP--APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE 378 Query: 563 PPYQLRPSLFVLSPI--KEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSS 620 P P+ +P KEPA +P+ +P P + P PK P +P P P+ Sbjct: 379 PA----PTTTKSAPTTPKEPAPTTPKKPAPTTPK--EPAPTTPKEPTPTTPKEPAPTTKE 432 Query: 621 PGLYTSPGQDSLQPTAVSPPYGGDISPVSP-------SRAWSPRAKQAPRPSFSTRNAGI 673 P T P +P + +P +P ++ SP + P P+ +T++A Sbjct: 433 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT-TTKSAPT 491 Query: 674 EAQDRRESLPTSPPWTPGASRPPSSLDGWVS----PGPWEPGRGSSMSSPPPLPPPPPMS 729 ++ + S P TP P ++ + + P P P + + + P P P Sbjct: 492 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 551 Query: 730 PSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSP---- 785 + + +P P+ A ++ + + K A E P P +P Sbjct: 552 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP---EKPAPTTPEELA 608 Query: 786 PRAPPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAP 845 P P P P P P +P+ A P + P P+ P P T+P+ P P Sbjct: 609 PTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT---TPKEPAP------TTPKEPAPTT 659 Query: 846 PR 847 P+ Sbjct: 660 PK 661 Score = 81.6 bits (200), Expect = 3e-15 Identities = 157/836 (18%), Positives = 270/836 (32%), Gaps = 116/836 (13%) Query: 60 AEVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQNSS 119 AEVH+P + + A P + + +++ P + + + + + + + S Sbjct: 64 AEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEI---TEEHSVS 120 Query: 120 EAQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTSTFSREATLIPS 179 E Q S+ + +S ST+ + A L K + T P+ Sbjct: 121 ENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKK--------PT 172 Query: 180 SRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTP-TKVYSEVHFTLAKPPSVVNR 238 +PP D S L + D +++ +TT KV + T AKP + R Sbjct: 173 PKPPVVDEAGSGL----------DNGDFKVTTPDTSTTQHNKVSTSPKITTAKP--INPR 220 Query: 239 TARPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERR 298 + P P + E S + + E + + + +E+ Sbjct: 221 PSLP-----PNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK- 274 Query: 299 MMGQRSPASERRPLGNFTAPPT-YTETLSTAPLASWVRSPPSYSVLYPSS----DPKSSH 353 + A + P A PT ET + P + + P + P+S +P + Sbjct: 275 -----TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT 329 Query: 354 LKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGE 413 +K + A ++ T ++P T + + Sbjct: 330 IKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT 389 Query: 414 VGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNL 473 E P A +EPAP P P A K P +P P Sbjct: 390 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEP--APTTKEPAPTTPKEPAPTAPK 447 Query: 474 SEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVAS 533 A E + S T P+ T S P++ K P AP + A Sbjct: 448 KPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP--APTTTKSAP 505 Query: 534 RSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKP 593 +P P PT KEPA +P+ +P P Sbjct: 506 TTPKE------------------PSPTTT---------------KEPAPTTPKEPAPTTP 532 Query: 594 SSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDS-LQPTAVSPPYGGDISPVSPSR 652 P PK P +P P P+ + T+P + + P +P ++P +P + Sbjct: 533 KKP--APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK 590 Query: 653 AWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSP-PWTPGASRPPSSLDGWVSPGPWEPG 711 +P + P P+ A ++ + P P P TP A+ P + + P P P Sbjct: 591 L-APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE----PAPTTPK 645 Query: 712 RGSSMSSPPPLPPPPPMSPSWSERSVSPLR-----PETEARPPSRQLQALLARNIINAAR 766 + + P P P + + + +P P T +P ++L + + Sbjct: 646 EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTC 705 Query: 767 RKSA--SPRSAGAENPRPFSP--PRAPPPPPP---------------PPPPPPRMRSPQP 807 K A +P+ P+ +P P+ P P P P P P+ +P Sbjct: 706 DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 765 Query: 808 ARPGSAAVPGAAFAPIPRSPLPAGPS--SCTSPRSPLPAPPRPFLYRRSPTDSDVS 861 + ++ P+ P P + T+P+ P P P PT S+VS Sbjct: 766 TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPE----TPPPTTSEVS 817 Score = 79.3 bits (194), Expect = 1e-14 Identities = 159/772 (20%), Positives = 246/772 (31%), Gaps = 77/772 (9%) Query: 46 QNREAQQSSPAPPPAEVHSPAADVNQNLASPSATLTTP-TSNSSHNPPATDVNQNPPATV 104 +NR ++ +P PP + + L + +TTP TS + HN +T + Sbjct: 164 KNRTKKKPTPKPPVVD------EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPI 217 Query: 105 VPQ-SLPLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTP 163 P+ SLP +S S E L N T + Q +E +T + S Sbjct: 218 NPRPSLPPNS--DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEK--TTSAKETQSIE 273 Query: 164 ATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYS 223 T+ + + ++ P A L + T + + S TPT + S Sbjct: 274 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPT-PTTPKEPASTTPKEPTPTTIKS 332 Query: 224 EVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPR 283 T K P+ + P + P T+ E +P K PAP P + Sbjct: 333 AP--TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT------PKEPAPTTTKEPAPTTT 384 Query: 284 PQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVL 343 + P +P + ++P AP T E T P +P + Sbjct: 385 KSAPTTPKEP----------APTTPKKP-----APTTPKEPAPTTPKEPTPTTPKEPAPT 429 Query: 344 YPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVT----PNPDLLDLV 399 P + P + A ++ T ++P T P P Sbjct: 430 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 489 Query: 400 QTADEK---RRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCL 456 T ++ + E P A +EPAP PA P + Sbjct: 490 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA-PTTP 548 Query: 457 KSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIES-SSHTPELARCPSPTMSL 515 K P KP P A E ++ E + TPE +P Sbjct: 549 KEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA 608 Query: 516 PSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLS 575 P++ + PT PA T P + N P PT P + P+ + Sbjct: 609 PTTPEEPT------PTTPEEPAPTTPKA-----AAPNTPKEPAPT--TPKEPAPT----T 651 Query: 576 PIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPT 635 P KEPA +P+ +P P P K P +P P P +P P + Sbjct: 652 P-KEPAPTTPKETAPTTPKG--TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 708 Query: 636 AVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRP 695 A + P G +P +P +P + P P T G +E PT+P Sbjct: 709 APTTPKG--TAPTTPKEP-APTTPKEPAP---TTPKGTAPTTLKEPAPTTPKKPAPKELA 762 Query: 696 PSSLDGWVSPGPWEPGRGSSMSSPPPLP-PPPPMSPSWSERSVSPLRPETEARPPSRQLQ 754 P++ G S +P + + P P P P +P + +P PET S Sbjct: 763 PTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP----KKPAPTTPETPPPTTSEVST 818 Query: 755 ALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQ 806 + + S AE P P + +P P P P P+ Sbjct: 819 PTTTKEPTTIHKSPDESTPELSAE-PTPKALENSPKEPGVPTTKTPAATKPE 869 Score = 68.2 bits (165), Expect = 3e-11 Identities = 171/866 (19%), Positives = 272/866 (31%), Gaps = 120/866 (13%) Query: 5 SEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQNREAQQSSPAPPPAEVHS 64 S+E SL + E +E + T + + AP + Sbjct: 230 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 289 Query: 65 PAADVNQNLASPSATLTT-PTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQNSSEAQL 123 P P+ T PT + P +T + P T+ +S P + + + Sbjct: 290 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI--KSAPTTP--KEPAPTTT 345 Query: 124 PSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTS--TFSREATLIPSSR 181 S T P T + P P E +T K P TT S T +E + Sbjct: 346 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT----KEPAPTTTKSAPTTPKEPAPTTPKK 401 Query: 182 PPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLAKPPSVVNRTAR 241 P + + +P + A TTP + KP + Sbjct: 402 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP---KKPAPTTPKEPA 458 Query: 242 PFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPP-SLPDRSPRPQRHIMSRSPMVERRMM 300 P + P T+ E SP K PAP S P + P +P + Sbjct: 459 PTTPKEPAPTTTKEPSPTTP------KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK--- 509 Query: 301 GQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSSD----PKSSHLKG 356 + SP + + P P T AP +P + P++ P + Sbjct: 510 -EPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 568 Query: 357 QAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGV 416 P + + K T EKP T +L T +E + Sbjct: 569 PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT--TPEEPTPTTPE----- 621 Query: 417 EEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEA 476 E P A A N +EPAP PA P +P P + + Sbjct: 622 EPAPTTPKAAAPNTPKEPAPTTPKEPA---------------PTTPKEPAPTTPKETAPT 666 Query: 477 SGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSP 536 + KG ++ P + P+P P++ K PT+ P Sbjct: 667 TPKGTAPTTLKEP------------APTTPKKPAPKELAPTTTKEPTST------TCDKP 708 Query: 537 ARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSL 596 A T P G P T + P P + +KEPA +P+ KP+ Sbjct: 709 APTTPK----GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK-----KPAPK 759 Query: 597 DLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSP 656 +L P KG P S +P+ ++P PT P +P +P + +P Sbjct: 760 ELAPTTTKG--PTSTTSDKPAPTTP--------KETAPTTPKEP-----APTTPKKP-AP 803 Query: 657 RAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGW---VSPGPWEPGRG 713 + P P+ S + ++ PT+ +P S P S + + P EPG Sbjct: 804 TTPETPPPTTSEVSTPTTTKE-----PTTIHKSPDESTPELSAEPTPKALENSPKEPGVP 858 Query: 714 SSMSSPPPLPPPPPMSPSWSERSVS-PLR--PETEARPP--SRQLQALLARNIINAARRK 768 ++ + P P M+ + +++ LR PET P +++ + + Sbjct: 859 TTKT---PAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITAT 915 Query: 769 SASPRSAGAENPRPFSPPRAPPPPPPPPPPPPR--------MRSP-QPARPGSAAVPGAA 819 + S ++ PF P + M P + A+P A A Sbjct: 916 TTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKA 975 Query: 820 FAPIPRSPLPAGPSSCTSPRSPLPAP 845 P P+ P A P TS + P P Sbjct: 976 TTPKPQKPTKA-PKKPTSTKKPKTMP 1000 Score = 38.9 bits (89), Expect = 0.022 Identities = 108/569 (18%), Positives = 183/569 (32%), Gaps = 116/569 (20%) Query: 50 AQQSSPAPPPAEVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSL 109 A ++ P P PA + A + TPT+ P + PA P+ L Sbjct: 552 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE----KPAPTTPEEL 607 Query: 110 -PLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTS 168 P + + + + P+ T A+ P+T P+ PA +TP Sbjct: 608 APTTPEEPTPTTPEEPAPTTPKAAAPNT------PKEPAP------------TTPKEPAP 649 Query: 169 TFSREA--TLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVH 226 T +E T + P + + L + P T A +E++ PT Sbjct: 650 TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA-------PTTTKEPTS 702 Query: 227 FTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGE--KAPAPQPPSLPDRSPRP 284 T KP + P + P T+ E +P + K PAP P + P P Sbjct: 703 TTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP----KKPAP 758 Query: 285 QRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLY 344 + + G S S++ AP T ET T P +P + Sbjct: 759 KE-------LAPTTTKGPTSTTSDK------PAPTTPKETAPTTPKEPAPTTPKKPAPTT 805 Query: 345 PSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADE 404 P + P ++ + V P T P T Sbjct: 806 PETPPPTT-----------------------------SEVSTPTTTKEP-------TTIH 829 Query: 405 KRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAK 464 K E+ E P AL N +EP +PAA + PE + K + Sbjct: 830 KSPDESTPELSAEPTPKAL----ENSPKEPGVPTTKTPAATK---PEMTTTAKDKTTERD 882 Query: 465 PKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTN 524 + P + +M K ++ T E ++ + T + S+ T Sbjct: 883 LRTTPETTTAAP-------------KMTKETATTTEKTTE-SKITATTTQVTSTTTQDTT 928 Query: 525 APGAFRVAS-RSPARTPPASLYHGYLPENGVL-RPEPTKQPPYQLRPSLFVLSPIKEPAK 582 F++ + ++ P + + ++ +PE T +P + S ++P K Sbjct: 929 P---FKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK 985 Query: 583 VSPRAASPAKPSSLDLVPNLPKGALPPSP 611 + S KP ++ P + K P+P Sbjct: 986 APKKPTSTKKPKTM---PRVRKPKTTPTP 1011 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 87.0 bits (214), Expect = 7e-17 Identities = 106/482 (21%), Positives = 183/482 (37%), Gaps = 60/482 (12%) Query: 386 KPKVTPNPDLL-DLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAA 444 +P + PN D + T +++ + ++ G E + +E ++ S Sbjct: 261 RPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTS--- 317 Query: 445 AEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPE 504 A+++ P + ++ AKP PK +E + KG L ++ E +S TP+ Sbjct: 318 AKDLAP-------TSKVLAKPTPK-----AETTTKGPALTTPKEPTPTTPK-EPASTTPK 364 Query: 505 LARCPSPTM--SLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQ 562 P+PT S P++ K P AP + A +P P + P TK+ Sbjct: 365 E---PTPTTIKSAPTTPKEP--APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE 419 Query: 563 PPYQLRPSLFVLSPI--KEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSS 620 P P+ +P KEPA +P+ +P P + P PK P +P P P+ Sbjct: 420 PA----PTTTKSAPTTPKEPAPTTPKKPAPTTPK--EPAPTTPKEPTPTTPKEPAPTTKE 473 Query: 621 PGLYTSPGQDSLQPTAVSPPYGGDISPVSP-------SRAWSPRAKQAPRPSFSTRNAGI 673 P T P +P + +P +P ++ SP + P P+ +T++A Sbjct: 474 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPT-TTKSAPT 532 Query: 674 EAQDRRESLPTSPPWTPGASRPPSSLDGWVS----PGPWEPGRGSSMSSPPPLPPPPPMS 729 ++ + S P TP P ++ + + P P P + + + P P P Sbjct: 533 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 592 Query: 730 PSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSP---- 785 + + +P P+ A ++ + + K A E P P +P Sbjct: 593 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP---EKPAPTTPEELA 649 Query: 786 PRAPPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAP 845 P P P P P P +P+ A P + P P+ P P T+P+ P P Sbjct: 650 PTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT---TPKEPAP------TTPKEPAPTT 700 Query: 846 PR 847 P+ Sbjct: 701 PK 702 Score = 81.6 bits (200), Expect = 3e-15 Identities = 157/836 (18%), Positives = 270/836 (32%), Gaps = 116/836 (13%) Query: 60 AEVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQNSS 119 AEVH+P + + A P + + +++ P + + + + + + + S Sbjct: 105 AEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEI---TEEHSVS 161 Query: 120 EAQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTSTFSREATLIPS 179 E Q S+ + +S ST+ + A L K + T P+ Sbjct: 162 ENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKK--------PT 213 Query: 180 SRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTP-TKVYSEVHFTLAKPPSVVNR 238 +PP D S L + D +++ +TT KV + T AKP + R Sbjct: 214 PKPPVVDEAGSGL----------DNGDFKVTTPDTSTTQHNKVSTSPKITTAKP--INPR 261 Query: 239 TARPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERR 298 + P P + E S + + E + + + +E+ Sbjct: 262 PSLP-----PNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK- 315 Query: 299 MMGQRSPASERRPLGNFTAPPT-YTETLSTAPLASWVRSPPSYSVLYPSS----DPKSSH 353 + A + P A PT ET + P + + P + P+S +P + Sbjct: 316 -----TSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT 370 Query: 354 LKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGE 413 +K + A ++ T ++P T + + Sbjct: 371 IKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT 430 Query: 414 VGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNL 473 E P A +EPAP P P A K P +P P Sbjct: 431 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEP--APTTKEPAPTTPKEPAPTAPK 488 Query: 474 SEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVAS 533 A E + S T P+ T S P++ K P AP + A Sbjct: 489 KPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEP--APTTTKSAP 546 Query: 534 RSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKP 593 +P P PT KEPA +P+ +P P Sbjct: 547 TTPKE------------------PSPTTT---------------KEPAPTTPKEPAPTTP 573 Query: 594 SSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDS-LQPTAVSPPYGGDISPVSPSR 652 P PK P +P P P+ + T+P + + P +P ++P +P + Sbjct: 574 KKP--APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK 631 Query: 653 AWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSP-PWTPGASRPPSSLDGWVSPGPWEPG 711 +P + P P+ A ++ + P P P TP A+ P + + P P P Sbjct: 632 L-APTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE----PAPTTPK 686 Query: 712 RGSSMSSPPPLPPPPPMSPSWSERSVSPLR-----PETEARPPSRQLQALLARNIINAAR 766 + + P P P + + + +P P T +P ++L + + Sbjct: 687 EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTC 746 Query: 767 RKSA--SPRSAGAENPRPFSP--PRAPPPPPP---------------PPPPPPRMRSPQP 807 K A +P+ P+ +P P+ P P P P P P+ +P Sbjct: 747 DKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 806 Query: 808 ARPGSAAVPGAAFAPIPRSPLPAGPS--SCTSPRSPLPAPPRPFLYRRSPTDSDVS 861 + ++ P+ P P + T+P+ P P P PT S+VS Sbjct: 807 TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPE----TPPPTTSEVS 858 Score = 79.3 bits (194), Expect = 1e-14 Identities = 159/772 (20%), Positives = 246/772 (31%), Gaps = 77/772 (9%) Query: 46 QNREAQQSSPAPPPAEVHSPAADVNQNLASPSATLTTP-TSNSSHNPPATDVNQNPPATV 104 +NR ++ +P PP + + L + +TTP TS + HN +T + Sbjct: 205 KNRTKKKPTPKPPVVD------EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPI 258 Query: 105 VPQ-SLPLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTP 163 P+ SLP +S S E L N T + Q +E +T + S Sbjct: 259 NPRPSLPPNS--DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEK--TTSAKETQSIE 314 Query: 164 ATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYS 223 T+ + + ++ P A L + T + + S TPT + S Sbjct: 315 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPT-PTTPKEPASTTPKEPTPTTIKS 373 Query: 224 EVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPR 283 T K P+ + P + P T+ E +P K PAP P + Sbjct: 374 AP--TTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTT------PKEPAPTTTKEPAPTTT 425 Query: 284 PQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVL 343 + P +P + ++P AP T E T P +P + Sbjct: 426 KSAPTTPKEP----------APTTPKKP-----APTTPKEPAPTTPKEPTPTTPKEPAPT 470 Query: 344 YPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVT----PNPDLLDLV 399 P + P + A ++ T ++P T P P Sbjct: 471 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 530 Query: 400 QTADEK---RRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCL 456 T ++ + E P A +EPAP PA P + Sbjct: 531 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA-PTTP 589 Query: 457 KSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIES-SSHTPELARCPSPTMSL 515 K P KP P A E ++ E + TPE +P Sbjct: 590 KEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA 649 Query: 516 PSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLS 575 P++ + PT PA T P + N P PT P + P+ + Sbjct: 650 PTTPEEPT------PTTPEEPAPTTPKA-----AAPNTPKEPAPT--TPKEPAPT----T 692 Query: 576 PIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPT 635 P KEPA +P+ +P P P K P +P P P +P P + Sbjct: 693 P-KEPAPTTPKETAPTTPKG--TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 749 Query: 636 AVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRP 695 A + P G +P +P +P + P P T G +E PT+P Sbjct: 750 APTTPKG--TAPTTPKEP-APTTPKEPAP---TTPKGTAPTTLKEPAPTTPKKPAPKELA 803 Query: 696 PSSLDGWVSPGPWEPGRGSSMSSPPPLP-PPPPMSPSWSERSVSPLRPETEARPPSRQLQ 754 P++ G S +P + + P P P P +P + +P PET S Sbjct: 804 PTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP----KKPAPTTPETPPPTTSEVST 859 Query: 755 ALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQ 806 + + S AE P P + +P P P P P+ Sbjct: 860 PTTTKEPTTIHKSPDESTPELSAE-PTPKALENSPKEPGVPTTKTPAATKPE 910 Score = 68.2 bits (165), Expect = 3e-11 Identities = 171/866 (19%), Positives = 272/866 (31%), Gaps = 120/866 (13%) Query: 5 SEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQNREAQQSSPAPPPAEVHS 64 S+E SL + E +E + T + + AP + Sbjct: 271 SKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAK 330 Query: 65 PAADVNQNLASPSATLTT-PTSNSSHNPPATDVNQNPPATVVPQSLPLSSIQQNSSEAQL 123 P P+ T PT + P +T + P T+ +S P + + + Sbjct: 331 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI--KSAPTTP--KEPAPTTT 386 Query: 124 PSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTS--TFSREATLIPSSR 181 S T P T + P P E +T K P TT S T +E + Sbjct: 387 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT----KEPAPTTTKSAPTTPKEPAPTTPKK 442 Query: 182 PPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLAKPPSVVNRTAR 241 P + + +P + A TTP + KP + Sbjct: 443 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP---KKPAPTTPKEPA 499 Query: 242 PFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPP-SLPDRSPRPQRHIMSRSPMVERRMM 300 P + P T+ E SP K PAP S P + P +P + Sbjct: 500 PTTPKEPAPTTTKEPSPTTP------KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK--- 550 Query: 301 GQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSSD----PKSSHLKG 356 + SP + + P P T AP +P + P++ P + Sbjct: 551 -EPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 609 Query: 357 QAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGV 416 P + + K T EKP T +L T +E + Sbjct: 610 PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT--TPEEPTPTTPE----- 662 Query: 417 EEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEA 476 E P A A N +EPAP PA P +P P + + Sbjct: 663 EPAPTTPKAAAPNTPKEPAPTTPKEPA---------------PTTPKEPAPTTPKETAPT 707 Query: 477 SGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSP 536 + KG ++ P + P+P P++ K PT+ P Sbjct: 708 TPKGTAPTTLKEP------------APTTPKKPAPKELAPTTTKEPTST------TCDKP 749 Query: 537 ARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSL 596 A T P G P T + P P + +KEPA +P+ KP+ Sbjct: 750 APTTPK----GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK-----KPAPK 800 Query: 597 DLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSP 656 +L P KG P S +P+ ++P PT P +P +P + +P Sbjct: 801 ELAPTTTKG--PTSTTSDKPAPTTP--------KETAPTTPKEP-----APTTPKKP-AP 844 Query: 657 RAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGW---VSPGPWEPGRG 713 + P P+ S + ++ PT+ +P S P S + + P EPG Sbjct: 845 TTPETPPPTTSEVSTPTTTKE-----PTTIHKSPDESTPELSAEPTPKALENSPKEPGVP 899 Query: 714 SSMSSPPPLPPPPPMSPSWSERSVS-PLR--PETEARPP--SRQLQALLARNIINAARRK 768 ++ + P P M+ + +++ LR PET P +++ + + Sbjct: 900 TTKT---PAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITAT 956 Query: 769 SASPRSAGAENPRPFSPPRAPPPPPPPPPPPPR--------MRSP-QPARPGSAAVPGAA 819 + S ++ PF P + M P + A+P A A Sbjct: 957 TTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKA 1016 Query: 820 FAPIPRSPLPAGPSSCTSPRSPLPAP 845 P P+ P A P TS + P P Sbjct: 1017 TTPKPQKPTKA-PKKPTSTKKPKTMP 1041 Score = 38.9 bits (89), Expect = 0.022 Identities = 108/569 (18%), Positives = 183/569 (32%), Gaps = 116/569 (20%) Query: 50 AQQSSPAPPPAEVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSL 109 A ++ P P PA + A + TPT+ P + PA P+ L Sbjct: 593 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE----KPAPTTPEEL 648 Query: 110 -PLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTS 168 P + + + + P+ T A+ P+T P+ PA +TP Sbjct: 649 APTTPEEPTPTTPEEPAPTTPKAAAPNT------PKEPAP------------TTPKEPAP 690 Query: 169 TFSREA--TLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVH 226 T +E T + P + + L + P T A +E++ PT Sbjct: 691 TTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA-------PTTTKEPTS 743 Query: 227 FTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGE--KAPAPQPPSLPDRSPRP 284 T KP + P + P T+ E +P + K PAP P + P P Sbjct: 744 TTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP----KKPAP 799 Query: 285 QRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLY 344 + + G S S++ AP T ET T P +P + Sbjct: 800 KE-------LAPTTTKGPTSTTSDK------PAPTTPKETAPTTPKEPAPTTPKKPAPTT 846 Query: 345 PSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADE 404 P + P ++ + V P T P T Sbjct: 847 PETPPPTT-----------------------------SEVSTPTTTKEP-------TTIH 870 Query: 405 KRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAK 464 K E+ E P AL N +EP +PAA + PE + K + Sbjct: 871 KSPDESTPELSAEPTPKAL----ENSPKEPGVPTTKTPAATK---PEMTTTAKDKTTERD 923 Query: 465 PKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTN 524 + P + +M K ++ T E ++ + T + S+ T Sbjct: 924 LRTTPETTTAAP-------------KMTKETATTTEKTTE-SKITATTTQVTSTTTQDTT 969 Query: 525 APGAFRVAS-RSPARTPPASLYHGYLPENGVL-RPEPTKQPPYQLRPSLFVLSPIKEPAK 582 F++ + ++ P + + ++ +PE T +P + S ++P K Sbjct: 970 P---FKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTK 1026 Query: 583 VSPRAASPAKPSSLDLVPNLPKGALPPSP 611 + S KP ++ P + K P+P Sbjct: 1027 APKKPTSTKKPKTM---PRVRKPKTTPTP 1052 >gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo sapiens] Length = 1188 Score = 83.6 bits (205), Expect = 8e-16 Identities = 95/337 (28%), Positives = 131/337 (38%), Gaps = 40/337 (11%) Query: 522 PTNAPGAFRVASRSPARTP-PASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEP 580 P APG + S P +P P+ P +L P P PP P VL + P Sbjct: 144 PGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPP---PPSMAPPPPPVLEALSPP 200 Query: 581 AKVSPRAASPAKPSSLDLVPNLPKGAL--PPSPALPRPSRSSPGLYTSPGQDSLQPTAVS 638 +S SP+ P+ D +P P A PP P +P P+ +P + G P V+ Sbjct: 201 HTLS----SPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVT 256 Query: 639 PPYGGDIS----PVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTS---PPWTPG 691 + D++ +RA PR+ P+ S N + + P S PP TP Sbjct: 257 K-WKSDVALNGRQAEATRASPPRSPAEPKGSALGPNP-----EPHLTFPRSFKVPPPTPV 310 Query: 692 ASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEARPPSR 751 + + +P E G++ +P LP PP S+ R S + P+ P Sbjct: 311 RTSSIPVQEAQEAPRKEE---GATKKAPSRLPLPP----SFHIRPASQVYPDRAPEPDCP 363 Query: 752 QLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPARPG 811 A + +S + AG P P PP APP PPP PP PP +P Sbjct: 364 GELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPP--AAPPLPCAQ 421 Query: 812 SAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAPPRP 848 AA P A F P+S PA P P PP P Sbjct: 422 KAAHPPAGFTKTPKSSSPA--------LKPKPNPPSP 450 Score = 62.8 bits (151), Expect = 1e-09 Identities = 187/817 (22%), Positives = 268/817 (32%), Gaps = 177/817 (21%) Query: 55 PAPPPAEVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSLPLSSI 114 P PPP P D+++ + L +P S + PP + PP ++ P P+ Sbjct: 140 PPPPPGPAPGPPQDISE--PPGGSPLPSPPSTAPPPPPLL-LEPPPPPSMAPPPPPVLEA 196 Query: 115 QQNSSEAQLPSNGTGP----ASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTSTF 170 PS T P + P A P PA P S Sbjct: 197 LSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAP-------------APPAPASPH 243 Query: 171 SREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQ---EMSGRAAATTPTKVYSEVHF 227 + L P + + S L Q S + E G A P E H Sbjct: 244 TVGTRLFPPGG--VTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNP-----EPHL 296 Query: 228 TLAK-----PPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAPA--PQPPSL--- 277 T + PP+ V ++ P + + +P E +KAP+ P PPS Sbjct: 297 TFPRSFKVPPPTPVRTSSIP--------VQEAQEAPRKEEGAT-KKAPSRLPLPPSFHIR 347 Query: 278 ------PDRSPRPQ--RHIMSRSPMVERRMMGQ-RSPASERR------------------ 310 PDR+P P + + +P R +GQ +S A ER Sbjct: 348 PASQVYPDRAPEPDCPGELKATAPASPR--LGQSQSQADERAGTPPPAPPLPPPAPPLPP 405 Query: 311 ---PLGNFTAPPTYTETLSTAPLASWVRSPPSYS-VLYPSSDPKSSHLKGQAVPA----- 361 PL APP + P A + ++P S S L P +P S + P Sbjct: 406 PAPPLPP-AAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDP 464 Query: 362 SKTGILEESMARR--GSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEE 419 S+ L +A GSR+ +P T P Q+ + K+ R + E+ Sbjct: 465 SQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAP------QSKEGKKGPR------LPEK 512 Query: 420 PFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGK 479 L A + P S + E A L P + P+ P ++ + Sbjct: 513 ETLLSLPAKD---TPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRN- 568 Query: 480 GAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPART 539 EL AR S EK S P P P + + N +++ Sbjct: 569 --ELEARLSSAAEKEAKPSIGSLP-----PKPRLE---GGRICENGADDDKLSKPVAKNL 618 Query: 540 PPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLV 599 PP S L P + QP L P++ P K +P A P K + Sbjct: 619 PPQST---------TLLPTTSLQPKAMLGPAI--------PPKATPEPAIPPKATLWPAT 661 Query: 600 PNLPKGALPPS--------PALPRPSRSSPGLY----TSPGQDS-LQPTAVSPPYGGDIS 646 P PK L P+ P P + S P + T P S L S P G Sbjct: 662 P--PKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEK 719 Query: 647 PVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPP---------S 697 P S + +A+ PS +TR + Q R S P +PG P S Sbjct: 720 PASQEVSTPSQARGEGSPSEATR---LPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQS 776 Query: 698 SLDGWVSP--------GPWEPGRGSSMSSPPPLPPPPPMSPSWSERSV-SPLRPETEARP 748 SL V+ G PG + PP LP PP S ++ + P+ E R Sbjct: 777 SLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERG 836 Query: 749 PSRQLQALLARNIINAARRKSASPRSAGAENPRPFSP 785 L + AAR+++ RS GA R P Sbjct: 837 SPMAL--------LLAARQRAQKGRSVGAALGRSSLP 865 Score = 59.7 bits (143), Expect = 1e-08 Identities = 154/658 (23%), Positives = 211/658 (32%), Gaps = 132/658 (20%) Query: 265 FGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTET 324 +G+ P PP P +P P + I P P TAPP Sbjct: 133 YGQDLLIPPPP--PGPAPGPPQDI-------------SEPPGGSPLPSPPSTAPPPPPLL 177 Query: 325 LSTAPLASWVRSPPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFV 384 L P S PP VL S P + L ++P I + Sbjct: 178 LEPPPPPSMAPPPPP--VLEALSPPHT--LSSPSIPTPPDFI--------PPAPPLAFLA 225 Query: 385 EKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAA 444 P P P R G V + AL + + PR A P Sbjct: 226 PPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKG 285 Query: 445 AEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPE 504 + + P L PR P P P + S + E + + +K P Sbjct: 286 SA-LGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKK--------APS 336 Query: 505 LARCPSPTMSLPSSWKYPTNAPGAF---RVASRSPARTPPASLYHGYLPEN-GVLRPEPT 560 P P+S YP AP + + +PA +P E G P P Sbjct: 337 RLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPA-SPRLGQSQSQADERAGTPPPAPP 395 Query: 561 KQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSS 620 PP P+ PA P AA P +P K A PP+ P SS Sbjct: 396 LPPP---------APPLPPPAPPLPPAAPP--------LPCAQKAAHPPAGFTKTPKSSS 438 Query: 621 PGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAW-SPRAKQAPRPSFSTRNAGIEAQDRR 679 P L P S + TA S P W P + R + G +DR Sbjct: 439 PALKPKPNPPSPENTASSAPVD-----------WRDPSQMEKLRNELAAYLCGSRREDRF 487 Query: 680 ESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMS-----SPPPLPPPPPMSPSWSE 734 S PG + P S +G GP P + + +S +PP +P S +E Sbjct: 488 LS------HRPGPTVAPQSKEG--KKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTE 539 Query: 735 RSVSP--------LRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRP---- 782 +P P+ P RQ++ L + +AA K A P S G+ P+P Sbjct: 540 TEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAA-EKEAKP-SIGSLPPKPRLEG 597 Query: 783 ------------FSPPRAPPPPPPPP---------------PPPPRMRSPQPARPGSAAV 815 S P A PP P P +P+PA P A + Sbjct: 598 GRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATL 657 Query: 816 PGAAFAPIPRSPL-PAGPSSCTS-PRSPLPAPPRPFLYRRS---PTDSDVSLDSEDSG 868 A P++ L PA P TS P +PL A P + + PT + + +DSG Sbjct: 658 WPAT---PPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSG 712 Score = 47.4 bits (111), Expect = 6e-05 Identities = 62/223 (27%), Positives = 74/223 (33%), Gaps = 57/223 (25%) Query: 686 PPWTPG-ASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPET 744 PP PG A PP + P ++ PP L PPP P + Sbjct: 140 PPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPP--------------PPS 185 Query: 745 EARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSPPR------APPPPPPPPPP 798 A PP L+AL + ++ S P F PP APPPPP P P Sbjct: 186 MAPPPPPVLEALSPPHTLS----------SPSIPTPPDFIPPAPPLAFLAPPPPPVPAPA 235 Query: 799 PPRMRSPQPA-----RPG-------SAAVPG----AAFAPIPRSPL--------PAGPSS 834 PP SP PG A+ G A A PRSP P Sbjct: 236 PPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPH 295 Query: 835 CTSPRSPLPAPPRPFLYRRSPTDSDVSLDSEDSGA--KSPGIL 875 T PRS PP P P ++ GA K+P L Sbjct: 296 LTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRL 338 Score = 43.1 bits (100), Expect = 0.001 Identities = 51/182 (28%), Positives = 59/182 (32%), Gaps = 50/182 (27%) Query: 704 SPGPWEPGR-GSSMSSPPPLPPPPPMSPSWSER----SVSPLRPETEARPPSRQLQALLA 758 S G PG+ G + PPP P P P P S P P T PP L+ Sbjct: 124 SVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLE---- 179 Query: 759 RNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPP---PPPPPPRMRSPQPARPGS--A 813 P PP PPPPP PP + SP P Sbjct: 180 -----------------------PPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIP 216 Query: 814 AVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAPPRPFLYRRSPT------DSDVSLDSEDS 867 P AF P P+PA P P PA P R P SDV+L+ + Sbjct: 217 PAPPLAFLAPPPPPVPA-------PAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQA 269 Query: 868 GA 869 A Sbjct: 270 EA 271 Score = 42.0 bits (97), Expect = 0.003 Identities = 148/675 (21%), Positives = 235/675 (34%), Gaps = 103/675 (15%) Query: 55 PAPPPAEVHSPAAD---VNQNLASPSATLT-TPTSNS-----SHNPPATD-------VNQ 98 P PPPA PAA Q A P A T TP S+S NPP+ + V+ Sbjct: 402 PLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDW 461 Query: 99 NPPATVVPQSLPLSSIQQNSS-EAQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLI 157 P+ + L++ S E + S+ GP P + P+ P +E TLL Sbjct: 462 RDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKE----TLL- 516 Query: 158 DKVSTPATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATT 217 S PA T P P S SS + P+ + S D + Sbjct: 517 ---SLPAKDT----------PPGVPEKSLGGSSLTETEAAPSLTLPSVDY-----IPQDS 558 Query: 218 PTKVYSEVHFTL-AKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPS 276 PT ++ L A+ S + A+P I + ++E + E +K P + Sbjct: 559 PTPSVRQIRNELEARLSSAAEKEAKP-SIGSLPPKPRLEGGRICENGADDDKLSKPVAKN 617 Query: 277 LPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRS 336 LP +S ++ + + + M+G PA + PP T +T P A+ + Sbjct: 618 LPPQSTT----LLPTTSLQPKAMLG---PAIPPKATPEPAIPPKATLWPATPPKATLGPA 670 Query: 337 PPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLL 396 P + P++ K++ G A+ ++ T + + + S P P Sbjct: 671 TPLKATSGPTTPLKAT--SGPAIASTATTLPTTTSQLMAEKDS------GPAGQPEKPAS 722 Query: 397 DLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCL 456 V T + R + E A + A + SP E C Sbjct: 723 QEVSTPSQARGEGSPSE--------ATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCH 774 Query: 457 KSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLP 516 +S + P A+G G + + + S+ T EL R P Sbjct: 775 QSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPV------ 828 Query: 517 SSWKYPTNAPGAFRVASRSPA---RTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFV 573 + +P A +A+R A R+ A+L LP G LR + S+F Sbjct: 829 TGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLP--GSLRDHSHQAEASS--DSIF- 883 Query: 574 LSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPAL--------PRPSRSSPGLYT 625 S P+S +VP LPK A SP PR R + G Sbjct: 884 --------------HSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTEL 929 Query: 626 SPGQDSLQPTAVSPPYGGDISPVS-PSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPT 684 S + +P +P ++P + P P++ +P PS S + E + E +P Sbjct: 930 SRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSP-PSPSNKREEEEEEFNFEVIPP 988 Query: 685 SPPWTPGASRPPSSL 699 P ++ P +L Sbjct: 989 PPEFSNDPEPPAPAL 1003 Score = 40.4 bits (93), Expect = 0.007 Identities = 37/115 (32%), Positives = 48/115 (41%), Gaps = 21/115 (18%) Query: 789 PPPPPPPPPPPPR------MRSPQPARPGSA---------AVPGAAFAPIPRSPLPA--G 831 PPPPP P P PP+ SP P+ P +A P + AP P L A Sbjct: 140 PPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSP 199 Query: 832 PSSCTSPRSPLP---APPRPFLYRRSPTDSDVSLDSEDSGAKSPGILGYNICPRG 883 P + +SP P P PP P L +P V + + A SP +G + P G Sbjct: 200 PHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPA-SPHTVGTRLFPPG 253 >gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo sapiens] Length = 1188 Score = 83.6 bits (205), Expect = 8e-16 Identities = 95/337 (28%), Positives = 131/337 (38%), Gaps = 40/337 (11%) Query: 522 PTNAPGAFRVASRSPARTP-PASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEP 580 P APG + S P +P P+ P +L P P PP P VL + P Sbjct: 144 PGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPP---PPSMAPPPPPVLEALSPP 200 Query: 581 AKVSPRAASPAKPSSLDLVPNLPKGAL--PPSPALPRPSRSSPGLYTSPGQDSLQPTAVS 638 +S SP+ P+ D +P P A PP P +P P+ +P + G P V+ Sbjct: 201 HTLS----SPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVT 256 Query: 639 PPYGGDIS----PVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTS---PPWTPG 691 + D++ +RA PR+ P+ S N + + P S PP TP Sbjct: 257 K-WKSDVALNGRQAEATRASPPRSPAEPKGSALGPNP-----EPHLTFPRSFKVPPPTPV 310 Query: 692 ASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEARPPSR 751 + + +P E G++ +P LP PP S+ R S + P+ P Sbjct: 311 RTSSIPVQEAQEAPRKEE---GATKKAPSRLPLPP----SFHIRPASQVYPDRAPEPDCP 363 Query: 752 QLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPARPG 811 A + +S + AG P P PP APP PPP PP PP +P Sbjct: 364 GELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPP--AAPPLPCAQ 421 Query: 812 SAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAPPRP 848 AA P A F P+S PA P P PP P Sbjct: 422 KAAHPPAGFTKTPKSSSPA--------LKPKPNPPSP 450 Score = 62.8 bits (151), Expect = 1e-09 Identities = 187/817 (22%), Positives = 268/817 (32%), Gaps = 177/817 (21%) Query: 55 PAPPPAEVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSLPLSSI 114 P PPP P D+++ + L +P S + PP + PP ++ P P+ Sbjct: 140 PPPPPGPAPGPPQDISE--PPGGSPLPSPPSTAPPPPPLL-LEPPPPPSMAPPPPPVLEA 196 Query: 115 QQNSSEAQLPSNGTGP----ASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTSTF 170 PS T P + P A P PA P S Sbjct: 197 LSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAP-------------APPAPASPH 243 Query: 171 SREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQ---EMSGRAAATTPTKVYSEVHF 227 + L P + + S L Q S + E G A P E H Sbjct: 244 TVGTRLFPPGG--VTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNP-----EPHL 296 Query: 228 TLAK-----PPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAPA--PQPPSL--- 277 T + PP+ V ++ P + + +P E +KAP+ P PPS Sbjct: 297 TFPRSFKVPPPTPVRTSSIP--------VQEAQEAPRKEEGAT-KKAPSRLPLPPSFHIR 347 Query: 278 ------PDRSPRPQ--RHIMSRSPMVERRMMGQ-RSPASERR------------------ 310 PDR+P P + + +P R +GQ +S A ER Sbjct: 348 PASQVYPDRAPEPDCPGELKATAPASPR--LGQSQSQADERAGTPPPAPPLPPPAPPLPP 405 Query: 311 ---PLGNFTAPPTYTETLSTAPLASWVRSPPSYS-VLYPSSDPKSSHLKGQAVPA----- 361 PL APP + P A + ++P S S L P +P S + P Sbjct: 406 PAPPLPP-AAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDP 464 Query: 362 SKTGILEESMARR--GSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEE 419 S+ L +A GSR+ +P T P Q+ + K+ R + E+ Sbjct: 465 SQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAP------QSKEGKKGPR------LPEK 512 Query: 420 PFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGK 479 L A + P S + E A L P + P+ P ++ + Sbjct: 513 ETLLSLPAKD---TPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRN- 568 Query: 480 GAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPART 539 EL AR S EK S P P P + + N +++ Sbjct: 569 --ELEARLSSAAEKEAKPSIGSLP-----PKPRLE---GGRICENGADDDKLSKPVAKNL 618 Query: 540 PPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLV 599 PP S L P + QP L P++ P K +P A P K + Sbjct: 619 PPQST---------TLLPTTSLQPKAMLGPAI--------PPKATPEPAIPPKATLWPAT 661 Query: 600 PNLPKGALPPS--------PALPRPSRSSPGLY----TSPGQDS-LQPTAVSPPYGGDIS 646 P PK L P+ P P + S P + T P S L S P G Sbjct: 662 P--PKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEK 719 Query: 647 PVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPP---------S 697 P S + +A+ PS +TR + Q R S P +PG P S Sbjct: 720 PASQEVSTPSQARGEGSPSEATR---LPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQS 776 Query: 698 SLDGWVSP--------GPWEPGRGSSMSSPPPLPPPPPMSPSWSERSV-SPLRPETEARP 748 SL V+ G PG + PP LP PP S ++ + P+ E R Sbjct: 777 SLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERG 836 Query: 749 PSRQLQALLARNIINAARRKSASPRSAGAENPRPFSP 785 L + AAR+++ RS GA R P Sbjct: 837 SPMAL--------LLAARQRAQKGRSVGAALGRSSLP 865 Score = 59.7 bits (143), Expect = 1e-08 Identities = 154/658 (23%), Positives = 211/658 (32%), Gaps = 132/658 (20%) Query: 265 FGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTET 324 +G+ P PP P +P P + I P P TAPP Sbjct: 133 YGQDLLIPPPP--PGPAPGPPQDI-------------SEPPGGSPLPSPPSTAPPPPPLL 177 Query: 325 LSTAPLASWVRSPPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFV 384 L P S PP VL S P + L ++P I + Sbjct: 178 LEPPPPPSMAPPPPP--VLEALSPPHT--LSSPSIPTPPDFI--------PPAPPLAFLA 225 Query: 385 EKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAA 444 P P P R G V + AL + + PR A P Sbjct: 226 PPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKG 285 Query: 445 AEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPE 504 + + P L PR P P P + S + E + + +K P Sbjct: 286 SA-LGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKK--------APS 336 Query: 505 LARCPSPTMSLPSSWKYPTNAPGAF---RVASRSPARTPPASLYHGYLPEN-GVLRPEPT 560 P P+S YP AP + + +PA +P E G P P Sbjct: 337 RLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPA-SPRLGQSQSQADERAGTPPPAPP 395 Query: 561 KQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSS 620 PP P+ PA P AA P +P K A PP+ P SS Sbjct: 396 LPPP---------APPLPPPAPPLPPAAPP--------LPCAQKAAHPPAGFTKTPKSSS 438 Query: 621 PGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAW-SPRAKQAPRPSFSTRNAGIEAQDRR 679 P L P S + TA S P W P + R + G +DR Sbjct: 439 PALKPKPNPPSPENTASSAPVD-----------WRDPSQMEKLRNELAAYLCGSRREDRF 487 Query: 680 ESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMS-----SPPPLPPPPPMSPSWSE 734 S PG + P S +G GP P + + +S +PP +P S +E Sbjct: 488 LS------HRPGPTVAPQSKEG--KKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTE 539 Query: 735 RSVSP--------LRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRP---- 782 +P P+ P RQ++ L + +AA K A P S G+ P+P Sbjct: 540 TEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAA-EKEAKP-SIGSLPPKPRLEG 597 Query: 783 ------------FSPPRAPPPPPPPP---------------PPPPRMRSPQPARPGSAAV 815 S P A PP P P +P+PA P A + Sbjct: 598 GRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATL 657 Query: 816 PGAAFAPIPRSPL-PAGPSSCTS-PRSPLPAPPRPFLYRRS---PTDSDVSLDSEDSG 868 A P++ L PA P TS P +PL A P + + PT + + +DSG Sbjct: 658 WPAT---PPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSG 712 Score = 47.4 bits (111), Expect = 6e-05 Identities = 62/223 (27%), Positives = 74/223 (33%), Gaps = 57/223 (25%) Query: 686 PPWTPG-ASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPET 744 PP PG A PP + P ++ PP L PPP P + Sbjct: 140 PPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPP--------------PPS 185 Query: 745 EARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSPPR------APPPPPPPPPP 798 A PP L+AL + ++ S P F PP APPPPP P P Sbjct: 186 MAPPPPPVLEALSPPHTLS----------SPSIPTPPDFIPPAPPLAFLAPPPPPVPAPA 235 Query: 799 PPRMRSPQPA-----RPG-------SAAVPG----AAFAPIPRSPL--------PAGPSS 834 PP SP PG A+ G A A PRSP P Sbjct: 236 PPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPH 295 Query: 835 CTSPRSPLPAPPRPFLYRRSPTDSDVSLDSEDSGA--KSPGIL 875 T PRS PP P P ++ GA K+P L Sbjct: 296 LTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRL 338 Score = 43.1 bits (100), Expect = 0.001 Identities = 51/182 (28%), Positives = 59/182 (32%), Gaps = 50/182 (27%) Query: 704 SPGPWEPGR-GSSMSSPPPLPPPPPMSPSWSER----SVSPLRPETEARPPSRQLQALLA 758 S G PG+ G + PPP P P P P S P P T PP L+ Sbjct: 124 SVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLE---- 179 Query: 759 RNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPP---PPPPPPRMRSPQPARPGS--A 813 P PP PPPPP PP + SP P Sbjct: 180 -----------------------PPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIP 216 Query: 814 AVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAPPRPFLYRRSPT------DSDVSLDSEDS 867 P AF P P+PA P P PA P R P SDV+L+ + Sbjct: 217 PAPPLAFLAPPPPPVPA-------PAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQA 269 Query: 868 GA 869 A Sbjct: 270 EA 271 Score = 42.0 bits (97), Expect = 0.003 Identities = 148/675 (21%), Positives = 235/675 (34%), Gaps = 103/675 (15%) Query: 55 PAPPPAEVHSPAAD---VNQNLASPSATLT-TPTSNS-----SHNPPATD-------VNQ 98 P PPPA PAA Q A P A T TP S+S NPP+ + V+ Sbjct: 402 PLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDW 461 Query: 99 NPPATVVPQSLPLSSIQQNSS-EAQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLI 157 P+ + L++ S E + S+ GP P + P+ P +E TLL Sbjct: 462 RDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKE----TLL- 516 Query: 158 DKVSTPATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATT 217 S PA T P P S SS + P+ + S D + Sbjct: 517 ---SLPAKDT----------PPGVPEKSLGGSSLTETEAAPSLTLPSVDY-----IPQDS 558 Query: 218 PTKVYSEVHFTL-AKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPS 276 PT ++ L A+ S + A+P I + ++E + E +K P + Sbjct: 559 PTPSVRQIRNELEARLSSAAEKEAKP-SIGSLPPKPRLEGGRICENGADDDKLSKPVAKN 617 Query: 277 LPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRS 336 LP +S ++ + + + M+G PA + PP T +T P A+ + Sbjct: 618 LPPQSTT----LLPTTSLQPKAMLG---PAIPPKATPEPAIPPKATLWPATPPKATLGPA 670 Query: 337 PPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLL 396 P + P++ K++ G A+ ++ T + + + S P P Sbjct: 671 TPLKATSGPTTPLKAT--SGPAIASTATTLPTTTSQLMAEKDS------GPAGQPEKPAS 722 Query: 397 DLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCL 456 V T + R + E A + A + SP E C Sbjct: 723 QEVSTPSQARGEGSPSE--------ATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCH 774 Query: 457 KSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLP 516 +S + P A+G G + + + S+ T EL R P Sbjct: 775 QSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPV------ 828 Query: 517 SSWKYPTNAPGAFRVASRSPA---RTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFV 573 + +P A +A+R A R+ A+L LP G LR + S+F Sbjct: 829 TGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLP--GSLRDHSHQAEASS--DSIF- 883 Query: 574 LSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPAL--------PRPSRSSPGLYT 625 S P+S +VP LPK A SP PR R + G Sbjct: 884 --------------HSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTEL 929 Query: 626 SPGQDSLQPTAVSPPYGGDISPVS-PSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPT 684 S + +P +P ++P + P P++ +P PS S + E + E +P Sbjct: 930 SRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSP-PSPSNKREEEEEEFNFEVIPP 988 Query: 685 SPPWTPGASRPPSSL 699 P ++ P +L Sbjct: 989 PPEFSNDPEPPAPAL 1003 Score = 40.4 bits (93), Expect = 0.007 Identities = 37/115 (32%), Positives = 48/115 (41%), Gaps = 21/115 (18%) Query: 789 PPPPPPPPPPPPR------MRSPQPARPGSA---------AVPGAAFAPIPRSPLPA--G 831 PPPPP P P PP+ SP P+ P +A P + AP P L A Sbjct: 140 PPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSP 199 Query: 832 PSSCTSPRSPLP---APPRPFLYRRSPTDSDVSLDSEDSGAKSPGILGYNICPRG 883 P + +SP P P PP P L +P V + + A SP +G + P G Sbjct: 200 PHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPA-SPHTVGTRLFPPG 253 >gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sapiens] Length = 1188 Score = 83.6 bits (205), Expect = 8e-16 Identities = 95/337 (28%), Positives = 131/337 (38%), Gaps = 40/337 (11%) Query: 522 PTNAPGAFRVASRSPARTP-PASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEP 580 P APG + S P +P P+ P +L P P PP P VL + P Sbjct: 144 PGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPP---PPSMAPPPPPVLEALSPP 200 Query: 581 AKVSPRAASPAKPSSLDLVPNLPKGAL--PPSPALPRPSRSSPGLYTSPGQDSLQPTAVS 638 +S SP+ P+ D +P P A PP P +P P+ +P + G P V+ Sbjct: 201 HTLS----SPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVT 256 Query: 639 PPYGGDIS----PVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTS---PPWTPG 691 + D++ +RA PR+ P+ S N + + P S PP TP Sbjct: 257 K-WKSDVALNGRQAEATRASPPRSPAEPKGSALGPNP-----EPHLTFPRSFKVPPPTPV 310 Query: 692 ASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEARPPSR 751 + + +P E G++ +P LP PP S+ R S + P+ P Sbjct: 311 RTSSIPVQEAQEAPRKEE---GATKKAPSRLPLPP----SFHIRPASQVYPDRAPEPDCP 363 Query: 752 QLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPARPG 811 A + +S + AG P P PP APP PPP PP PP +P Sbjct: 364 GELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPP--AAPPLPCAQ 421 Query: 812 SAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAPPRP 848 AA P A F P+S PA P P PP P Sbjct: 422 KAAHPPAGFTKTPKSSSPA--------LKPKPNPPSP 450 Score = 62.8 bits (151), Expect = 1e-09 Identities = 187/817 (22%), Positives = 268/817 (32%), Gaps = 177/817 (21%) Query: 55 PAPPPAEVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQSLPLSSI 114 P PPP P D+++ + L +P S + PP + PP ++ P P+ Sbjct: 140 PPPPPGPAPGPPQDISE--PPGGSPLPSPPSTAPPPPPLL-LEPPPPPSMAPPPPPVLEA 196 Query: 115 QQNSSEAQLPSNGTGP----ASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTSTF 170 PS T P + P A P PA P S Sbjct: 197 LSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAP-------------APPAPASPH 243 Query: 171 SREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQ---EMSGRAAATTPTKVYSEVHF 227 + L P + + S L Q S + E G A P E H Sbjct: 244 TVGTRLFPPGG--VTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNP-----EPHL 296 Query: 228 TLAK-----PPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAPA--PQPPSL--- 277 T + PP+ V ++ P + + +P E +KAP+ P PPS Sbjct: 297 TFPRSFKVPPPTPVRTSSIP--------VQEAQEAPRKEEGAT-KKAPSRLPLPPSFHIR 347 Query: 278 ------PDRSPRPQ--RHIMSRSPMVERRMMGQ-RSPASERR------------------ 310 PDR+P P + + +P R +GQ +S A ER Sbjct: 348 PASQVYPDRAPEPDCPGELKATAPASPR--LGQSQSQADERAGTPPPAPPLPPPAPPLPP 405 Query: 311 ---PLGNFTAPPTYTETLSTAPLASWVRSPPSYS-VLYPSSDPKSSHLKGQAVPA----- 361 PL APP + P A + ++P S S L P +P S + P Sbjct: 406 PAPPLPP-AAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDP 464 Query: 362 SKTGILEESMARR--GSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEE 419 S+ L +A GSR+ +P T P Q+ + K+ R + E+ Sbjct: 465 SQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAP------QSKEGKKGPR------LPEK 512 Query: 420 PFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGK 479 L A + P S + E A L P + P+ P ++ + Sbjct: 513 ETLLSLPAKD---TPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRN- 568 Query: 480 GAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPART 539 EL AR S EK S P P P + + N +++ Sbjct: 569 --ELEARLSSAAEKEAKPSIGSLP-----PKPRLE---GGRICENGADDDKLSKPVAKNL 618 Query: 540 PPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLV 599 PP S L P + QP L P++ P K +P A P K + Sbjct: 619 PPQST---------TLLPTTSLQPKAMLGPAI--------PPKATPEPAIPPKATLWPAT 661 Query: 600 PNLPKGALPPS--------PALPRPSRSSPGLY----TSPGQDS-LQPTAVSPPYGGDIS 646 P PK L P+ P P + S P + T P S L S P G Sbjct: 662 P--PKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEK 719 Query: 647 PVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPP---------S 697 P S + +A+ PS +TR + Q R S P +PG P S Sbjct: 720 PASQEVSTPSQARGEGSPSEATR---LPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQS 776 Query: 698 SLDGWVSP--------GPWEPGRGSSMSSPPPLPPPPPMSPSWSERSV-SPLRPETEARP 748 SL V+ G PG + PP LP PP S ++ + P+ E R Sbjct: 777 SLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERG 836 Query: 749 PSRQLQALLARNIINAARRKSASPRSAGAENPRPFSP 785 L + AAR+++ RS GA R P Sbjct: 837 SPMAL--------LLAARQRAQKGRSVGAALGRSSLP 865 Score = 59.7 bits (143), Expect = 1e-08 Identities = 154/658 (23%), Positives = 211/658 (32%), Gaps = 132/658 (20%) Query: 265 FGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTET 324 +G+ P PP P +P P + I P P TAPP Sbjct: 133 YGQDLLIPPPP--PGPAPGPPQDI-------------SEPPGGSPLPSPPSTAPPPPPLL 177 Query: 325 LSTAPLASWVRSPPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFV 384 L P S PP VL S P + L ++P I + Sbjct: 178 LEPPPPPSMAPPPPP--VLEALSPPHT--LSSPSIPTPPDFI--------PPAPPLAFLA 225 Query: 385 EKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAA 444 P P P R G V + AL + + PR A P Sbjct: 226 PPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKG 285 Query: 445 AEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPE 504 + + P L PR P P P + S + E + + +K P Sbjct: 286 SA-LGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKK--------APS 336 Query: 505 LARCPSPTMSLPSSWKYPTNAPGAF---RVASRSPARTPPASLYHGYLPEN-GVLRPEPT 560 P P+S YP AP + + +PA +P E G P P Sbjct: 337 RLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPA-SPRLGQSQSQADERAGTPPPAPP 395 Query: 561 KQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSS 620 PP P+ PA P AA P +P K A PP+ P SS Sbjct: 396 LPPP---------APPLPPPAPPLPPAAPP--------LPCAQKAAHPPAGFTKTPKSSS 438 Query: 621 PGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAW-SPRAKQAPRPSFSTRNAGIEAQDRR 679 P L P S + TA S P W P + R + G +DR Sbjct: 439 PALKPKPNPPSPENTASSAPVD-----------WRDPSQMEKLRNELAAYLCGSRREDRF 487 Query: 680 ESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMS-----SPPPLPPPPPMSPSWSE 734 S PG + P S +G GP P + + +S +PP +P S +E Sbjct: 488 LS------HRPGPTVAPQSKEG--KKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTE 539 Query: 735 RSVSP--------LRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRP---- 782 +P P+ P RQ++ L + +AA K A P S G+ P+P Sbjct: 540 TEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAA-EKEAKP-SIGSLPPKPRLEG 597 Query: 783 ------------FSPPRAPPPPPPPP---------------PPPPRMRSPQPARPGSAAV 815 S P A PP P P +P+PA P A + Sbjct: 598 GRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATL 657 Query: 816 PGAAFAPIPRSPL-PAGPSSCTS-PRSPLPAPPRPFLYRRS---PTDSDVSLDSEDSG 868 A P++ L PA P TS P +PL A P + + PT + + +DSG Sbjct: 658 WPAT---PPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSG 712 Score = 47.4 bits (111), Expect = 6e-05 Identities = 62/223 (27%), Positives = 74/223 (33%), Gaps = 57/223 (25%) Query: 686 PPWTPG-ASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPET 744 PP PG A PP + P ++ PP L PPP P + Sbjct: 140 PPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPP--------------PPS 185 Query: 745 EARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSPPR------APPPPPPPPPP 798 A PP L+AL + ++ S P F PP APPPPP P P Sbjct: 186 MAPPPPPVLEALSPPHTLS----------SPSIPTPPDFIPPAPPLAFLAPPPPPVPAPA 235 Query: 799 PPRMRSPQPA-----RPG-------SAAVPG----AAFAPIPRSPL--------PAGPSS 834 PP SP PG A+ G A A PRSP P Sbjct: 236 PPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPH 295 Query: 835 CTSPRSPLPAPPRPFLYRRSPTDSDVSLDSEDSGA--KSPGIL 875 T PRS PP P P ++ GA K+P L Sbjct: 296 LTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRL 338 Score = 43.1 bits (100), Expect = 0.001 Identities = 51/182 (28%), Positives = 59/182 (32%), Gaps = 50/182 (27%) Query: 704 SPGPWEPGR-GSSMSSPPPLPPPPPMSPSWSER----SVSPLRPETEARPPSRQLQALLA 758 S G PG+ G + PPP P P P P S P P T PP L+ Sbjct: 124 SVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLE---- 179 Query: 759 RNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPP---PPPPPPRMRSPQPARPGS--A 813 P PP PPPPP PP + SP P Sbjct: 180 -----------------------PPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIP 216 Query: 814 AVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAPPRPFLYRRSPT------DSDVSLDSEDS 867 P AF P P+PA P P PA P R P SDV+L+ + Sbjct: 217 PAPPLAFLAPPPPPVPA-------PAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQA 269 Query: 868 GA 869 A Sbjct: 270 EA 271 Score = 42.0 bits (97), Expect = 0.003 Identities = 148/675 (21%), Positives = 235/675 (34%), Gaps = 103/675 (15%) Query: 55 PAPPPAEVHSPAAD---VNQNLASPSATLT-TPTSNS-----SHNPPATD-------VNQ 98 P PPPA PAA Q A P A T TP S+S NPP+ + V+ Sbjct: 402 PLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDW 461 Query: 99 NPPATVVPQSLPLSSIQQNSS-EAQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLI 157 P+ + L++ S E + S+ GP P + P+ P +E TLL Sbjct: 462 RDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKE----TLL- 516 Query: 158 DKVSTPATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATT 217 S PA T P P S SS + P+ + S D + Sbjct: 517 ---SLPAKDT----------PPGVPEKSLGGSSLTETEAAPSLTLPSVDY-----IPQDS 558 Query: 218 PTKVYSEVHFTL-AKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPS 276 PT ++ L A+ S + A+P I + ++E + E +K P + Sbjct: 559 PTPSVRQIRNELEARLSSAAEKEAKP-SIGSLPPKPRLEGGRICENGADDDKLSKPVAKN 617 Query: 277 LPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLASWVRS 336 LP +S ++ + + + M+G PA + PP T +T P A+ + Sbjct: 618 LPPQSTT----LLPTTSLQPKAMLG---PAIPPKATPEPAIPPKATLWPATPPKATLGPA 670 Query: 337 PPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVTPNPDLL 396 P + P++ K++ G A+ ++ T + + + S P P Sbjct: 671 TPLKATSGPTTPLKAT--SGPAIASTATTLPTTTSQLMAEKDS------GPAGQPEKPAS 722 Query: 397 DLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCL 456 V T + R + E A + A + SP E C Sbjct: 723 QEVSTPSQARGEGSPSE--------ATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCH 774 Query: 457 KSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLP 516 +S + P A+G G + + + S+ T EL R P Sbjct: 775 QSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPV------ 828 Query: 517 SSWKYPTNAPGAFRVASRSPA---RTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFV 573 + +P A +A+R A R+ A+L LP G LR + S+F Sbjct: 829 TGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLP--GSLRDHSHQAEASS--DSIF- 883 Query: 574 LSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPAL--------PRPSRSSPGLYT 625 S P+S +VP LPK A SP PR R + G Sbjct: 884 --------------HSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTEL 929 Query: 626 SPGQDSLQPTAVSPPYGGDISPVS-PSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPT 684 S + +P +P ++P + P P++ +P PS S + E + E +P Sbjct: 930 SRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSP-PSPSNKREEEEEEFNFEVIPP 988 Query: 685 SPPWTPGASRPPSSL 699 P ++ P +L Sbjct: 989 PPEFSNDPEPPAPAL 1003 Score = 40.4 bits (93), Expect = 0.007 Identities = 37/115 (32%), Positives = 48/115 (41%), Gaps = 21/115 (18%) Query: 789 PPPPPPPPPPPPR------MRSPQPARPGSA---------AVPGAAFAPIPRSPLPA--G 831 PPPPP P P PP+ SP P+ P +A P + AP P L A Sbjct: 140 PPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSP 199 Query: 832 PSSCTSPRSPLP---APPRPFLYRRSPTDSDVSLDSEDSGAKSPGILGYNICPRG 883 P + +SP P P PP P L +P V + + A SP +G + P G Sbjct: 200 PHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPA-SPHTVGTRLFPPG 253 >gi|160707881 formin 2 [Homo sapiens] Length = 1722 Score = 83.2 bits (204), Expect = 1e-15 Identities = 117/410 (28%), Positives = 133/410 (32%), Gaps = 67/410 (16%) Query: 497 ESSSHTPELARCPSPTMSLPSSW--KYPTNA---PGAFRVASRSPARTPPASLYHGYLPE 551 ESSS P L P P LP P+ A P + P PP LP Sbjct: 865 ESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPP-------LPG 917 Query: 552 NGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKP----SSLDLVPNLPKGAL 607 G+ P P P + P + P P AA P P + + L P LP + Sbjct: 918 AGI--PPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGI 975 Query: 608 PPSPALPR----PSRSSPGLYTSPGQDSLQPTAVSPPY---GGDISPVSPSRAWSPRAKQ 660 PP P LP P PG P L + PP G I P P P A Sbjct: 976 PPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGAGIPPPPPLPGAGIPPPPPL----PGAGI 1030 Query: 661 APRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPP 720 P P AGI P PP PP L G P P P G+ + PP Sbjct: 1031 PPPPPLP--GAGI---------PPPPPLPGAGIPPPPPLPGAGIPPP-PPLPGAGIPPPP 1078 Query: 721 PLP----PPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAG 776 PLP PPPP P PL P PP + A AG Sbjct: 1079 PLPGAGIPPPPPLPGAGIPPPPPL-PGVGIPPPPP---------LPGAGIPPPPPLPGAG 1128 Query: 777 AENPRPFSPPRAPPPPP-------PPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLP 829 P P PPPPP PPPP P P P PG+ P + P P Sbjct: 1129 IPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPP 1188 Query: 830 AGPSSCTSPRSPLPA----PPRPFLYRRSPTDSDVSLDSEDSGAKSPGIL 875 P P PLP PP P P L +G P +L Sbjct: 1189 PLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLL 1238 Score = 75.1 bits (183), Expect = 3e-13 Identities = 93/320 (29%), Positives = 112/320 (35%), Gaps = 39/320 (12%) Query: 558 EPTKQPPYQLRPSL------FVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSP 611 +P QPP+ + V S K + P SS + P L G +PP P Sbjct: 824 QPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSM-PGL--GMVPPPP 880 Query: 612 ALPRPSRSSPGLYTS--PGQDSLQPTAVSPPY-----GGDISPVSPSRAWSPRAKQAPRP 664 P P + P L ++ P LQ T + PP G I P P P A P P Sbjct: 881 P-PLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPL----PGAGILPLP 935 Query: 665 SFSTRNAGIEAQDRRESLPTSPPWTPGASRP-PSSLDGWVSPGPWEPGRGSSMSSPPPLP 723 ++P PP PGA P P L G P P P G+ + PPPLP Sbjct: 936 PLPGAGIPPPPPLPGAAIPPPPP-LPGAGIPLPPPLPGAGIPPP-PPLPGAGIPPPPPLP 993 Query: 724 ----PPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPR-SAGAE 778 PPPP P PL PP + + A P AG Sbjct: 994 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 1053 Query: 779 NPRPFSPPRAPPPPP-------PPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAG 831 P P PPPPP PPPP P P P PG+ P + P P Sbjct: 1054 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPL 1113 Query: 832 PSSCTSPRSPLPA---PPRP 848 P + P PLP PP P Sbjct: 1114 PGAGIPPPPPLPGAGIPPPP 1133 Score = 55.1 bits (131), Expect = 3e-07 Identities = 87/303 (28%), Positives = 100/303 (33%), Gaps = 66/303 (21%) Query: 549 LPENGVLRPEPTKQ---PPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKG 605 LP G+ P P PP P + P P P P + + P LP Sbjct: 1014 LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP-PPPPLPGAGIPPPPPLPGA 1072 Query: 606 ALPPSPALPR----PSRSSPGLYTSPGQDSLQPTAVSPPY---GGDISPVSPSRAWSPRA 658 +PP P LP P PG P L + PP G I P P P A Sbjct: 1073 GIPPPPPLPGAGIPPPPPLPGAGIPP-PPPLPGVGIPPPPPLPGAGIPPPPPL----PGA 1127 Query: 659 KQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSS 718 P P AGI P PP PP L G P P P G+ + Sbjct: 1128 GIPPPPPLP--GAGI---------PPPPPLPRVGIPPPPPLPGAGIPPP-PPLPGAGIPP 1175 Query: 719 PPPLP----PPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRS 774 PPPLP PPPP P PL P PP P Sbjct: 1176 PPPLPGVGIPPPPPLPGVGIPPPPPL-PGAGIPPP----------------------PPL 1212 Query: 775 AGAENPRPFSPPRAPP----PPPP--PPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPL 828 G P +PP PP PPPP P PP + PQ GS+ +P PL Sbjct: 1213 PGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLL--PQ---VGSSTLPTPQVCGFLPPPL 1267 Query: 829 PAG 831 P+G Sbjct: 1268 PSG 1270 Score = 53.9 bits (128), Expect = 7e-07 Identities = 57/214 (26%), Positives = 73/214 (34%), Gaps = 38/214 (17%) Query: 668 TRNAGIEAQDRRESLPTSPPWTPGASRPP-----SSLDGWVSPGPWEPGRGSSMSSPPPL 722 T G+ + LP PP PGA P S + VSP S + Sbjct: 749 TEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSIS 808 Query: 723 PPPPPMSPSWSERSVSPLRPETEARPP---SRQLQALLARNIINAARRKS--ASPRSAGA 777 PPPP S WS P ++PP S + Q ++ +A + SP Sbjct: 809 QPPPPPSLLWSAGQGQP-----GSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPC 863 Query: 778 ENPRPFSPPRAPPPPPPPP--------------PPPPRMRSPQPARPGSAAVPGAAFAPI 823 P PPPPPP P PP ++ + P +PGA P Sbjct: 864 TESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPP 923 Query: 824 PR------SPLPAGPSSCTSPRSPLPA---PPRP 848 P PLP P + P PLP PP P Sbjct: 924 PPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPP 957 Score = 30.4 bits (67), Expect = 7.8 Identities = 71/305 (23%), Positives = 102/305 (33%), Gaps = 42/305 (13%) Query: 375 GSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEP 434 GS +++F T DLL +Q A ++Q+ Q L + QQ+ Sbjct: 178 GSDTDIYSF---HSATEQEDLLSDIQQAIRLQQQQQQ----------QLQLQLQQQQQQQ 224 Query: 435 APRDRASPAAAEEVV-PEWASCLKSPRI---------QAKPKPKPNQNLSEASGKGAELY 484 + PAA V P+ + L R +A P Q LS S L Sbjct: 225 QLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLA 284 Query: 485 ARRQSRMEKYVIESS--SHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTPPA 542 A + + S P L PSS +P G A+ +P R Sbjct: 285 AEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGD 344 Query: 543 SLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNL 602 + G E P P + P + +P + + A P P++ Sbjct: 345 TDEEG---EEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAA------- 394 Query: 603 PKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAP 662 +LP SPA P P +P +S P + SP S S SPR K+ P Sbjct: 395 --ASLPGSPA-PSQRCFKPYPLITPCYIKTTTRQLSSP---NHSP-SQSPNQSPRIKRRP 447 Query: 663 RPSFS 667 PS S Sbjct: 448 EPSLS 452 >gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] Length = 1970 Score = 82.0 bits (201), Expect = 2e-15 Identities = 105/385 (27%), Positives = 142/385 (36%), Gaps = 25/385 (6%) Query: 498 SSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRP 557 SS + P SP+ S P+S Y +PG + +SP+ +P + Y P P Sbjct: 1578 SSPYIPSPGGAMSPSYS-PTSPAYEPRSPGGY--TPQSPSYSPTSPSYSPTSPSYSPTSP 1634 Query: 558 E--PTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPA-KPSSLDLVPNLPKGALPPSPALP 614 PT PS SP P S SP+ P+S P P SP P Sbjct: 1635 NYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY----SPTSP 1690 Query: 615 RPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIE 674 S +SP SP S PT SP Y SP SPS + + + PS+S + Sbjct: 1691 SYSPTSPSY--SPTSPSYSPT--SPSY----SPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1742 Query: 675 AQDRRESLPTSPPWTPGASR--PPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSW 732 S PTSP +TP + P S SP S +SP P P SP+ Sbjct: 1743 PTSPNYS-PTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTS 1801 Query: 733 SERSVSPLR--PETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPR--PFSPPRA 788 S S R P++ PS + + + + + + + S +P P SP + Sbjct: 1802 PSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYS 1861 Query: 789 PPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAPPRP 848 P P P P + P + + P SP+ S SP SP +P P Sbjct: 1862 PTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSP 1921 Query: 849 FLYRRSPTDSDVSLDSEDSGAKSPG 873 SPT S S SPG Sbjct: 1922 KYSPTSPTYSPTSPKGSTYSPTSPG 1946 Score = 72.4 bits (176), Expect = 2e-12 Identities = 87/310 (28%), Positives = 122/310 (39%), Gaps = 25/310 (8%) Query: 575 SPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPS--PALPRPSRSSPGLYT------S 626 SP P SP + P+ P +P+ P GA+ PS P P SPG YT S Sbjct: 1562 SPAWSPTPGSPGSPGPSSP----YIPS-PGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYS 1616 Query: 627 PGQDSLQPTAVS-PPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTS 685 P S PT+ S P + SP SPS + + + PS+S + S PTS Sbjct: 1617 PTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS-PTS 1675 Query: 686 PPWTPGASRPPSSLDGWVSPGPWEPGRG-SSMSSPPPLPPPPPMSPSWSERSVSPLRPET 744 P ++P + PS S P P +S S P P P SPS+S S S P + Sbjct: 1676 PSYSPTS---PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS-YSPTS 1731 Query: 745 EARPPSRQLQALLARNIINAARRKSASPRSAGAENPR--PFSPPRAPPPPPPPPPPPPRM 802 + P+ + + N + + + S +P P SP P P P P Sbjct: 1732 PSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYS 1791 Query: 803 RSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAPPRPFLYRRSPTDSDVSL 862 + P S + ++ P+SP S SP SP +P P + +PT S Sbjct: 1792 PTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSP---KYTPTSPSYSP 1848 Query: 863 DSEDSGAKSP 872 S + SP Sbjct: 1849 SSPEYTPTSP 1858 Score = 60.1 bits (144), Expect = 9e-09 Identities = 78/281 (27%), Positives = 104/281 (37%), Gaps = 28/281 (9%) Query: 584 SPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGG 643 SP S P + P+ A SP +PG SPG S P SP GG Sbjct: 1532 SPSVGSGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPSS--PYIPSP--GG 1587 Query: 644 DISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTP-GASRPPSSLDGW 702 +SP ++SP + P++ R+ G PTSP ++P S P+S + Sbjct: 1588 AMSP-----SYSPTS-----PAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYS 1637 Query: 703 VSPGPWEPGRGSSMSSPPPLPPPPPMSPSWS--ERSVSPLRPETEARPPSRQLQALLARN 760 + + P +S S P P P SPS+S S SP P PS + Sbjct: 1638 PTSPSYSP---TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS-----PTS 1689 Query: 761 IINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPARPGSAAVPGAAF 820 + S SP S P P +P P P P S P P S + + Sbjct: 1690 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP-SYSPTSPNY 1748 Query: 821 APIPRSPLPAGPSSCTSPRSPLPAPPRPFLYRRSPTDSDVS 861 +P + P PS SP SP +P P SP S S Sbjct: 1749 SPTSPNYTPTSPS--YSPTSPSYSPTSPNYTPTSPNYSPTS 1787 Score = 39.3 bits (90), Expect = 0.017 Identities = 47/175 (26%), Positives = 63/175 (36%), Gaps = 9/175 (5%) Query: 696 PSSLDGWVSPGPWEPGRGSSMSSPPPLPPP--------PPMSPSWSERSVSPLRPETEAR 747 P+++ G + GP GS+ S + P P +WS S + P Sbjct: 1487 PTNIPGLGAAGPTGMFFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGF 1546 Query: 748 PPSRQLQAL-LARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQ 806 PS A + A SP S G +P SP A P P P RSP Sbjct: 1547 SPSAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPG 1606 Query: 807 PARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAPPRPFLYRRSPTDSDVS 861 P S + + + P SP + S SP SP +P P SP+ S S Sbjct: 1607 GYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTS 1661 >gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] Length = 904 Score = 82.0 bits (201), Expect = 2e-15 Identities = 146/593 (24%), Positives = 217/593 (36%), Gaps = 120/593 (20%) Query: 256 RSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMMG------------QR 303 RS RR + P+P+ + P R P P RH SRSP+ RR R Sbjct: 307 RSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSR 366 Query: 304 SPASERRPLGNFTAPPTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSSHLKG-QAVPAS 362 S + ++P ++PP T LS + R PS P PK+ H Q + Sbjct: 367 SRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPP---PKTRHSPTPQQSNRT 423 Query: 363 KTGILEESMARRGSRKSMFTFVEK---PKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEE 419 + + S R + + EK P P P ++L ++ ++K + + + Sbjct: 424 RKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRR 483 Query: 420 PFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGK 479 + Q + + D S +++E+ P+ S +K+ + + + P+++ S + K Sbjct: 484 QYRR-------QNQQSSSDSGSSSSSEDERPK-RSHVKNGEVGRRRRHSPSRSASPSPRK 535 Query: 480 GAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPART 539 + + R R R PSP PT RSP+ Sbjct: 536 RQKETSPRGRRR---------------RSPSPP---------PTRR-------RRSPSPA 564 Query: 540 PPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLV 599 PP P P P PP + PS P + SP PS Sbjct: 565 PPPRRRRTPTPPPRRRTPSP---PPRRRSPS---------PRRYSPPIQRRYSPSP---- 608 Query: 600 PNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSRA--WSPR 657 P + A PP P R S S P + + SPP SPV+ R+ S + Sbjct: 609 PPKRRTASPPPPPKRRASPSPP---------PKRRVSHSPPPKQRSSPVTKRRSPSLSSK 659 Query: 658 AKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMS 717 ++ PS STR A ++R S P+ P P S P P R + S Sbjct: 660 HRKGSSPSRSTREARSPQPNKRHS-PSPRPRAPQTSSSPP------------PVRRGASS 706 Query: 718 SPPPLPPPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGA 777 SP P P S P+R + P + +A A + RR S+S +G Sbjct: 707 SPQRRQSPSP--------STRPIRRVSRTPEPKKIKKA--ASPSPQSVRRVSSSRSVSG- 755 Query: 778 ENPRPFSPPRAPPPPPPPPPPPPRMRSPQPARPGSAAVP-GAAFAPIPRSPLP 829 SP A PP PP P ++S P+ S AVP A +P P SP P Sbjct: 756 ------SPEPAAKKPPAPPSP---VQSQSPSTNWSPAVPVKKAKSPTP-SPSP 798 Score = 75.1 bits (183), Expect = 3e-13 Identities = 158/674 (23%), Positives = 234/674 (34%), Gaps = 131/674 (19%) Query: 255 ERSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRP-LG 313 ERS RR ++P+P+ S P R R + H SRSP R SPA E++ Sbjct: 167 ERSRSPRRRK--SRSPSPRRRSSPVRRERKRSH--SRSPR-HRTKSRSPSPAPEKKEKTP 221 Query: 314 NFTAP------PTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSSHLKGQAVPASKTGIL 367 P P+ E ST+ + + P PS + S K + ++ Sbjct: 222 ELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSR 281 Query: 368 EESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEA 427 +S +R SR T +P+ RR R + + + Sbjct: 282 SKSRSRTRSRSPSHT---RPR-----------------RRHRSR-------------SRS 308 Query: 428 SNFQQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARR 487 + ++ P+PR R SP P R P + ++ + SG + + R Sbjct: 309 YSPRRRPSPRRRPSPR--RRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSR 366 Query: 488 QSRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLYHG 547 K + +S P R SP+ S P P SP TPP H Sbjct: 367 SRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRP------------SPPATPPPKTRHS 414 Query: 548 YLPENGVLRPEPTKQPPYQLRPSLFVLSPIKEPAKVSPR-------AASPA-KPSSLDLV 599 PT Q + R S +SP + KV+ + SPA KP ++L Sbjct: 415 -----------PTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELS 463 Query: 600 PNLPK--GALPPSPALPR---------PSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPV 648 + G + + ++ + S S G +S + + + V G Sbjct: 464 ESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRH 523 Query: 649 SPSRAWSP---------------RAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGAS 693 SPSR+ SP R +P P+ R+ RR PT PP S Sbjct: 524 SPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPS 583 Query: 694 RPPSSLDGWVSPGPWEPGRGSSMS-SPPPL-----PPPPPMSPSWSERSVSPLRPETEAR 747 PP SP + P S SPPP PPPPP + S P R + + Sbjct: 584 PPPRRRSP--SPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRA--SPSPPPKRRVSHSP 639 Query: 748 PPSRQLQALLARNI--INAARRKSASPRSAGAE--NPRPF-----SPPRAPPPPPPPPPP 798 PP ++ + R +++ RK +SP + E +P+P SP P PPP Sbjct: 640 PPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPP 699 Query: 799 PPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAPPRPFLYRRSPTDS 858 R S P R S + + R+P P + A P P RR + Sbjct: 700 VRRGASSSPQRRQSPSPSTRPIRRVSRTPEP--------KKIKKAASPSPQSVRRVSSSR 751 Query: 859 DVSLDSEDSGAKSP 872 VS E + K P Sbjct: 752 SVSGSPEPAAKKPP 765 Score = 58.5 bits (140), Expect = 3e-08 Identities = 71/266 (26%), Positives = 103/266 (38%), Gaps = 44/266 (16%) Query: 652 RAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPG 711 R+ SPR +++ PS R++ + + +R + T S P+ +P EP Sbjct: 168 RSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPS 227 Query: 712 ---------RGSSMSS------PPPLPPPPPMSP---SWSERSVSPLRPETEARPPSRQL 753 +S S P P+P P SP S E+ RP + +R SR Sbjct: 228 VKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSR 287 Query: 754 QALLARNIINAARR-----KSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSP-QP 807 + + RR +S SPR + RP R PP PPPP R RSP + Sbjct: 288 TRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRR 347 Query: 808 ARPGSAAVPGAAFAPI---PRSPLPAGPSSCTSP------RSPLPAPPR----------- 847 R SA++ G++ + RSP P +SP SP +PPR Sbjct: 348 RRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATP 407 Query: 848 PFLYRRSPTDSDVSLDSEDSGAKSPG 873 P R SPT + + + SPG Sbjct: 408 PPKTRHSPTPQQSNRTRKSRVSVSPG 433 Score = 48.9 bits (115), Expect = 2e-05 Identities = 114/488 (23%), Positives = 166/488 (34%), Gaps = 91/488 (18%) Query: 400 QTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVVPEWASCLKSP 459 Q D+ +R +++ E E+ + + P+PR R+SP E S +SP Sbjct: 147 QDEDKDKRDKEEKESSREKRERSRSPRRRK-SRSPSPRRRSSPVRRERK----RSHSRSP 201 Query: 460 RIQAK---PKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTM--- 513 R + K P P P E K EL E V E++S T ++ + P P Sbjct: 202 RHRTKSRSPSPAP-----EKKEKTPELPEPSVKVKEPSVQEATS-TSDILKVPKPEPIPE 255 Query: 514 -SLPSSWKYP--------------TNAPGAFRVASRSPARTPPA----SLYHGYLPENGV 554 PS K + + R SRSP+ T P S Y P Sbjct: 256 PKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRR-- 313 Query: 555 LRPEPTKQP-PYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPAL 613 RP P ++P P + P + P + SP +SL + + SP Sbjct: 314 -RPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPK 372 Query: 614 PRPSRSSPGLYTSPGQDS--LQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNA 671 P R+S SP + + L P+A SPP SP P+ + +P P S R Sbjct: 373 KPPKRTS-----SPPRKTRRLSPSA-SPPRRRHRP--SPPATPPPKTRHSPTPQQSNRT- 423 Query: 672 GIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPS 731 R+ + SP T G + SP P P P + S Sbjct: 424 ------RKSRVSVSPGRTSGKVTKHKGTE--------------KRESPSPAPKPRKVELS 463 Query: 732 WSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSAS---PRSAGAENPRPFSPPRA 788 SE ++ RQ + ++ ++ S+ P+ + +N R Sbjct: 464 ESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRH 523 Query: 789 PPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAPPRP 848 P P P R + P RSP P RSP PAPP Sbjct: 524 SPSRSASPSPRKRQKETSPRGRRR------------RSP---SPPPTRRRRSPSPAPP-- 566 Query: 849 FLYRRSPT 856 RR+PT Sbjct: 567 PRRRRTPT 574 Score = 46.6 bits (109), Expect = 1e-04 Identities = 140/614 (22%), Positives = 209/614 (34%), Gaps = 117/614 (19%) Query: 55 PAPPPAEVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQ---------------- 98 P P SP ++ AS S + ++ +S+ S +PP + Sbjct: 334 PPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSAS 393 Query: 99 --------NPPATVVPQSLPLSSIQQN-----SSEAQLPSNGTGPASK-PSTLCADGQPQ 144 +PPAT P++ + QQ+ S + P +G +K T + Sbjct: 394 PPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSP 453 Query: 145 AP-AEEVRCSTLLIDKVSTPATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVV 203 AP +V S DK A S R ++ +SD SSS D +P V Sbjct: 454 APKPRKVELSESEEDKGGKMAAADSVQQRR-QYRRQNQQSSSDSGSSSSSEDERPKRSHV 512 Query: 204 SADQEMSGRAAATTPTKVYSEVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERR 263 + GR +P++ S PS R +P G + SP RR Sbjct: 513 KNGE--VGRRRRHSPSRSAS---------PSPRKRQKE----TSPRGRRRRSPSPPPTRR 557 Query: 264 HFGEKAPAPQPPSLPDRSPRPQRHIMSRSPMVERRMMGQR--SPASERR-----PLGNFT 316 ++P+P PP R+P P + SP RR R SP +RR P T Sbjct: 558 ---RRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRT 614 Query: 317 A----PPTYTETLSTAPLASWVRSPPSYSVLYP-----SSDPKSSHLKGQAVPASKTGIL 367 A PP + S P SPP P S S H KG + P+ T Sbjct: 615 ASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSS-PSRST--R 671 Query: 368 EESMARRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQ------RDQGEVGVEEEPF 421 E + R S P+ + +P + ++ +RRQ R V EP Sbjct: 672 EARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPK 731 Query: 422 ALGAEASNFQQ-------------EPAPRDRASPAAAEEVVPEWASCLKSPRIQAK---- 464 + AS Q P P + PA V + S SP + K Sbjct: 732 KIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKS 791 Query: 465 --PKPKPNQNL-SEASGKGAELYARRQSRMEKYVIESSSHTPELARCPSPTMSLPSSWKY 521 P P P +N E GK + ++ + +K + H E A + ++ Sbjct: 792 PTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAV------ 845 Query: 522 PTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRPSLFVLSP-IKEP 580 P A A+ + A+ P V PEP K+ + +L L ++E Sbjct: 846 ---TPAAIAAATTTLAQEEP------------VAAPEPKKETESEAEDNLDDLEKHLREK 890 Query: 581 AKVSPRAASPAKPS 594 A S R A + S Sbjct: 891 ALRSMRKAQVSPQS 904 Score = 38.5 bits (88), Expect = 0.028 Identities = 139/644 (21%), Positives = 208/644 (32%), Gaps = 112/644 (17%) Query: 49 EAQQSSPAPPPAEVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQS 108 +++ SPAP E + + + PS T TS+ P + + P P+ Sbjct: 206 KSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPE--PKEPSPEK 263 Query: 109 LPLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTS 168 +S ++ E P + + S+ T P R + P+ Sbjct: 264 ---NSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRR 320 Query: 169 TFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFT 228 R T PP S S + + ++ +S S + + +P K Sbjct: 321 PSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPK-------- 372 Query: 229 LAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPSL-----PDRSPR 283 KPP RT+ P P T ++ S RR PA PP P +S R Sbjct: 373 --KPPK---RTSSP-----PRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNR 422 Query: 284 PQRHIMSRSPM-----------VERRMMGQRSPA--------SERRPLGNFTAPPTYTET 324 ++ +S SP E+R +P SE G A + + Sbjct: 423 TRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQR 482 Query: 325 LSTAPLASWVRSPPSYSVLYPSSDPKSSHLKG------------QAVPASKTGILEESMA 372 S S PK SH+K ++ S +E+ Sbjct: 483 RQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSP 542 Query: 373 RRGSRKSMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQ 432 R R+S + + +P+P A RR+R P ++ Sbjct: 543 RGRRRRSPSPPPTRRRRSPSP--------APPPRRRRTPTPPPRRRTP-----SPPPRRR 589 Query: 433 EPAPRDRASPAAAEEVVPE------WASCLKSPRIQAKPKPKPNQNLSEA---SGKGAEL 483 P+PR R SP P AS P+ +A P P P + +S + + + + Sbjct: 590 SPSPR-RYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPV 648 Query: 484 YARRQ----------SRMEKYVIESSSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVAS 533 RR S + E+ S P PSP P + P P R AS Sbjct: 649 TKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSP---PPVRRGAS 705 Query: 534 RSPARTPPASLYHGYLPENGVLR-PEPTK---------QPPYQLRPSLFVLSPIKEPAKV 583 SP R S P V R PEP K Q ++ S V + AK Sbjct: 706 SSPQRRQSPS--PSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKK 763 Query: 584 SPRAASPAKPSS--LDLVPNLP--KGALP-PSPALPRPSRSSPG 622 P SP + S + P +P K P PSP+ PR S G Sbjct: 764 PPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGG 807 Score = 37.0 bits (84), Expect = 0.083 Identities = 56/258 (21%), Positives = 89/258 (34%), Gaps = 49/258 (18%) Query: 48 REAQQSSPAPPPAEVHSPAADVNQNLASPSATLTTPTSNS---------SHNPPATDVNQ 98 R + SPAPPP +P + SP +P+ S +PP Sbjct: 556 RRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTA 615 Query: 99 NPPATVVPQSLPLSSIQQNSSEAQLPSNGTGPASK---PSTLCADGQPQAPAEEVRCSTL 155 +PP ++ P ++ S + P + P +K PS + +P+ R Sbjct: 616 SPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTR---- 671 Query: 156 LIDKVSTPATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAA 215 A + R + PS RP A P T S+ R A+ Sbjct: 672 -------EARSPQPNKRHS---PSPRPRA-------------PQT---SSSPPPVRRGAS 705 Query: 216 TTPTKVYSEVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPP 275 ++P + S T +P V+RT P I+ SP RR ++ + P Sbjct: 706 SSPQRRQSPSPST--RPIRRVSRTPEPKKIKKAASP-----SPQSVRRVSSSRSVSGSPE 758 Query: 276 SLPDRSPRPQRHIMSRSP 293 + P P + S+SP Sbjct: 759 PAAKKPPAPPSPVQSQSP 776 >gi|60460889 Myb protein P42POP [Homo sapiens] Length = 399 Score = 79.3 bits (194), Expect = 1e-14 Identities = 86/290 (29%), Positives = 117/290 (40%), Gaps = 54/290 (18%) Query: 581 AKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPR----------PSRSSPGLYTSPGQD 630 A + P A+P + + P P PP A P+ R+ ++ G Sbjct: 118 AILGPGVAAPGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSS 177 Query: 631 SLQPTA---VSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPP 687 S +P A +P GG P+ +++P PS A Q R +L PP Sbjct: 178 SPEPWARPSCTPQEGG---------CPRPKERESPPPS-----ALQPVQLPRLALSPPPP 223 Query: 688 WTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEAR 747 P PP + V+P P SPPP PP PP + S S+ S+ LR + E Sbjct: 224 APPLPPPPPLAQ---VAPSP---------PSPPP-PPRPPPTLSASDPSLDFLRAQQETA 270 Query: 748 PPSRQLQALLARNIINAARRKSAS-PRSAGAENPRPFSPPRAPPPPPPPPPPPPRMR--- 803 R+L L + + + SA P G P PP PPPPPPPPPP P + Sbjct: 271 NAIRELAGTLRQGLAKLSEALSALLPLLPGT--PVDSLPPPLPPPPPPPPPPRPVLPPPA 328 Query: 804 -----SPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAPPRP 848 +P+P +A V GA A R + A S +PR P PAP P Sbjct: 329 PKVEITPEPVSVVAAVVDGAVVA--ARGVIIAPRSEEGAPRPP-PAPLPP 375 Score = 61.2 bits (147), Expect = 4e-09 Identities = 86/304 (28%), Positives = 111/304 (36%), Gaps = 49/304 (16%) Query: 526 PGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLR-PSLFVLSPIK-EPAKV 583 PG + + A PPA+ P+ QPP P +VLS + E + Sbjct: 122 PGVAAPGAGAGAEEPPAA---------------PSSQPPPPSACPQRYVLSEDRREDRRA 166 Query: 584 SPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQDSLQPT-----AVS 638 A S A SS + P P PRP SP +LQP A+S Sbjct: 167 DTSAHSKAGSSSPE--PWARPSCTPQEGGCPRPKERE-----SPPPSALQPVQLPRLALS 219 Query: 639 PPYGGDISPVSPSRAW------SPRAKQAPRPSFSTRNAGIE---AQDRRESLPTSPPWT 689 PP P P A SP P P+ S + ++ AQ + T Sbjct: 220 PPPPAPPLPPPPPLAQVAPSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGT 279 Query: 690 --PGASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEAR 747 G ++ +L + P PG S PPPLPPPPP P + P P+ E Sbjct: 280 LRQGLAKLSEALSALL---PLLPGTPVD-SLPPPLPPPPPPPPP-PRPVLPPPAPKVEIT 334 Query: 748 PPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQP 807 P + A + + AAR +PRS PRP P AP PP PP R P Sbjct: 335 PEPVSVVAAVVDGAVVAARGVIIAPRSEEGA-PRP---PPAPLPPHDSPPHKRRKGFPTR 390 Query: 808 ARPG 811 R G Sbjct: 391 KRRG 394 Score = 56.6 bits (135), Expect = 1e-07 Identities = 85/323 (26%), Positives = 109/323 (33%), Gaps = 101/323 (31%) Query: 667 STRNAGIEAQDR--------RESLPTSPPWTPGASRPPSSLDGW----------VSPGPW 708 S + G E Q R +E L P T GA P++ D + + PG Sbjct: 68 SWKRTGQEVQKRWNDFKRRTKEKLARVPHSTQGAG--PAAEDAFSAEEETIFAILGPGVA 125 Query: 709 EPGRGSSMSSPPPLP---PPPPM-----------------------------SPS-WSER 735 PG G+ PP P PPPP SP W+ Sbjct: 126 APGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARP 185 Query: 736 SVSPL-----RPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSPPRA-- 788 S +P RP+ PP LQ + R + SP P P PP A Sbjct: 186 SCTPQEGGCPRPKERESPPPSALQPV-------QLPRLALSPPPPAPPLPPP--PPLAQV 236 Query: 789 ---PPPPPPPPPPPPRMRSPQPA---------------------RPGSAAVPGA--AFAP 822 PP PPPPP PPP + + P+ R G A + A A P Sbjct: 237 APSPPSPPPPPRPPPTLSASDPSLDFLRAQQETANAIRELAGTLRQGLAKLSEALSALLP 296 Query: 823 I-PRSPLPAGPSSCTSPRSPLPAPPRPFLYRRSP----TDSDVSLDSEDSGAKSPGILGY 877 + P +P+ + P P P P PPRP L +P T VS+ + G Sbjct: 297 LLPGTPVDSLPPPLPPPPPP-PPPPRPVLPPPAPKVEITPEPVSVVAAVVDGAVVAARGV 355 Query: 878 NICPRGWNGSLRLKRGSLPAEAS 900 I PR G+ R LP S Sbjct: 356 IIAPRSEEGAPRPPPAPLPPHDS 378 >gi|41281612 zinc finger protein 828 [Homo sapiens] Length = 812 Score = 79.0 bits (193), Expect = 2e-14 Identities = 114/397 (28%), Positives = 149/397 (37%), Gaps = 59/397 (14%) Query: 509 PSPTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPE---PTKQPPY 565 P + LP K P N S P P S+ L VL PE PT P Sbjct: 105 PVKSPPLPEHQKIPCN--------SAEPKSIPALSMETQKL--GSVLSPESPKPTPLTPL 154 Query: 566 QLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLP-----KGALPPSPALPRPSRSS 620 + + V+SP + SP + PA SS + ++P K A PSP +P+ S Sbjct: 155 EPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVS 214 Query: 621 PGLYTS------PGQDSLQPTAVSPPYGGDISPVSPSRA-----WSPRAKQAPRPSFSTR 669 P + P + S P + PP SP SP A W P +P S R Sbjct: 215 PESVKATLSNPKPQKQSHFPETLGPPSAS--SPESPVLAASPEPWGPSPAASPESRKSAR 272 Query: 670 NAGIEAQDRRESLPTSP-PWT--PGASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPP 726 E R+ S SP PW P S P VSPG W+PG PP P P Sbjct: 273 TTSPE--PRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPG-------PPGSPRPW 323 Query: 727 PMSPSWSERSVSPLRPETEARP-PSRQLQALLARNIINAARRKSASPRSAGAENPRPFSP 785 +PS S P +P P P + + ++ SAS +S+ +P + Sbjct: 324 KSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWKSSSV-SPSSWKS 382 Query: 786 PRAPPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAP 845 P A P PP R +P + AVP +P R P GP RSP +P Sbjct: 383 PPASPESWKSGPPELRKTAPTLSPEHWKAVP--PVSPELRKP---GPPLSPEIRSPAGSP 437 Query: 846 P------RPFLYRRSPTD---SDVSLDSEDSGAKSPG 873 P L++ SP S SLD +S S G Sbjct: 438 ELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRG 474 Score = 52.0 bits (123), Expect = 2e-06 Identities = 99/375 (26%), Positives = 146/375 (38%), Gaps = 77/375 (20%) Query: 436 PRDRASPAAAEEVVPEWASCLKSPRIQAKPKP-KPNQNLSEASGKGAELYARRQSRMEKY 494 P+ + E + P AS +SP + A P+P P+ S S K A + + Sbjct: 225 PKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRK---- 280 Query: 495 VIESSSHTPEL----------ARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTP---- 540 S S +PE R P+P +S P SWK PG+ R +P+ + Sbjct: 281 --PSPSESPEPWKPFPAVSPEPRRPAPAVS-PGSWK--PGPPGSPRPWKSNPSASSGPWK 335 Query: 541 PASLYHGYLPENGVLRPEPTKQP-PYQLRPSLFVLSPIKEPAKVSPRA--ASPAKPSSLD 597 PA P G +P P+ P P++ PS V S + + VSP + + PA P S Sbjct: 336 PAKPAPSVSP--GPWKPIPSVSPGPWKPTPS--VSSASWKSSSVSPSSWKSPPASPESWK 391 Query: 598 ------------LVPNLPKGALPPSPALPRPSRS-SPGLYTSPGQDSLQPTAVSPPYGGD 644 L P K P SP L +P SP + + G L+ + SP D Sbjct: 392 SGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSP----D 447 Query: 645 ISPVSPS-RAWSPRAKQAPRPSFSTRNAG---------IEAQ-----DRRESLPTSPPWT 689 + +SP R SP + P S+R IE Q + R+ P+ P + Sbjct: 448 LWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSES 507 Query: 690 PGAS----RPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETE 745 P A+ +P S+D EP + + P P PP SP +R++ P P Sbjct: 508 PKAASDIWKPVLSIDT-------EPRKPALF--PEPAKTAPPASPEARKRALFP-EPRKH 557 Query: 746 ARPPSRQLQALLARN 760 A P AL + + Sbjct: 558 ALFPELPKSALFSES 572 Score = 33.5 bits (75), Expect = 0.92 Identities = 114/472 (24%), Positives = 167/472 (35%), Gaps = 75/472 (15%) Query: 218 PTKVYSEVHFTLAKP---PSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQP 274 P + ++ A+P P++ T + + +P +P+ ++ +P Q Sbjct: 110 PLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSVVSPELQT 169 Query: 275 PSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAP-PTYTETLSTAPLASW 333 P LP SP P + SP + + P E + L +P P +S + + Sbjct: 170 P-LP--SPEPSKPASVSSPEPPKSV-----PVCESQKLAPVPSPEPQKPAPVSPESVKAT 221 Query: 334 VRSP-PSYSVLYPSS--DPKSSHLKGQAVPASKTGILEESMARRGSRKSMFTFVEKPKVT 390 + +P P +P + P +S + + AS A SRKS T +P+ Sbjct: 222 LSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPR-K 280 Query: 391 PNPD-----LLDLVQTADEKRRQRDQGEVGVEEE--PFALGAEASNFQQEPAPRDRASPA 443 P+P + E RR G + P + SN P A PA Sbjct: 281 PSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPA 340 Query: 444 AAEEVVPEWASCLKSPRIQAKPKP-KPNQNLSEASGKGAELYARRQSRMEKYVIESSSHT 502 + P W P P P KP ++S AS K + + S Sbjct: 341 PSVSPGP-W-----KPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGP 394 Query: 503 PELARCPSPTMSLPSSWK-YPTNAPGAFRVAS------RSPARTPPASLYHGYLPENGVL 555 PEL R +PT+S P WK P +P + RSPA +P G P+ L Sbjct: 395 PEL-RKTAPTLS-PEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGS-PDLWKL 451 Query: 556 RPEPTKQPPYQL------------RPSLFVLSPIKEPAKV---------------SPRAA 588 P+ K P L P L+ S EP K SP+AA Sbjct: 452 SPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKAA 511 Query: 589 SPA-KPS-SLDLVPNLPKGALPPSPALPRPSRS----SPGLYTSPGQDSLQP 634 S KP S+D P P AL P PA P S L+ P + +L P Sbjct: 512 SDIWKPVLSIDTEPRKP--ALFPEPAKTAPPASPEARKRALFPEPRKHALFP 561 Score = 32.7 bits (73), Expect = 1.6 Identities = 97/473 (20%), Positives = 149/473 (31%), Gaps = 98/473 (20%) Query: 49 EAQQSSPAPPPAEVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPATVVPQS 108 E Q P+P P++ PA+ ++SP + P S P PA V P+S Sbjct: 166 ELQTPLPSPEPSK---PAS-----VSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPES 217 Query: 109 L------PLSSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAEEVRCSTLLIDKVST 162 + P Q + E P + + P S L A +P P + Sbjct: 218 VKATLSNPKPQKQSHFPETLGPPSASSPES--PVLAASPEPWGP---------------S 260 Query: 163 PATTTSTFSREATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVY 222 PA + + T P R P+ + + P K + Sbjct: 261 PAASPESRKSARTTSPEPRKPSP---------------------------SESPEPWKPF 293 Query: 223 SEVHFTLAKP-PSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQP-----PS 276 V +P P+V + +P PG + +P + PAP Sbjct: 294 PAVSPEPRRPAPAVSPGSWKP---GPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKP 350 Query: 277 LPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGN----FTAPPTYTETLSTAPLAS 332 +P SP P + S S + SP+S + P + + PP +T T Sbjct: 351 IPSVSPGPWKPTPSVSSASWK--SSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEH 408 Query: 333 WVRSPPSYSVLYPSSDPKSSHLKGQA------VPASKTGILEESMARRGSRKSMFTFVEK 386 W PP L P S ++ A P+ + + S +R + + F E Sbjct: 409 WKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPES 468 Query: 387 PKVT--PNPDLLDLVQTADEKR----RQRDQGEVGVEEEP----------FALGAEASNF 430 K + +PDL + ++ R G G E P ++ E Sbjct: 469 QKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGPSESPKAASDIWKPVLSIDTEPRKP 528 Query: 431 QQEPAPRDRASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAEL 483 P P A PA+ E + PR A P L S K EL Sbjct: 529 ALFPEPAKTAPPASPE---ARKRALFPEPRKHALFPELPKSALFSESQKAVEL 578 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 77.8 bits (190), Expect = 4e-14 Identities = 148/676 (21%), Positives = 231/676 (34%), Gaps = 122/676 (18%) Query: 263 RHFGEKAPAPQPPSLPDRSPRPQRH----IMSRSPMVERRMMGQRSPASERRPLGNFTAP 318 + +GE P +P P +P + + + M RR G S R A Sbjct: 537 KKYGELPPIEKPVDPPPFMFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRK--KQPAS 594 Query: 319 PTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRK 378 P + + S R+ PS ++ S+ K + V S + EE+ + S K Sbjct: 595 PDGRTSPINEDIRSSGRNSPS------AASTSSNDSKAETVKKSAKKVKEEASSPLKSNK 648 Query: 379 SMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRD 438 ++ KV + + D + K ++ + E E + + + N + P+D Sbjct: 649 R-----QREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKD 703 Query: 439 RASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIES 498 + SP I P P+ N++ S++S + L A+ + + Sbjct: 704 IDQDNRST-----------SPSI---PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTP 749 Query: 499 --SSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTPP--------ASLYHGY 548 SS P + P+P + ++ P +P A + ++ A T P A H Sbjct: 750 APSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQ 809 Query: 549 LPENGVLRPEPTKQPPYQ--------------LRPSLFVLSPI-KEPAKVSPRAASPAKP 593 P + P P+ PP Q +P L P + P P P Sbjct: 810 RPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPP 869 Query: 594 SSLDLVPNLPKGALP----PSPALPRPSRSSPGLYTS------PGQDSLQPTAVSPPYGG 643 L P +G P P+ A P S P ++ P + L P ++ P+ Sbjct: 870 QPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIK 929 Query: 644 DISPVSPSRAWSPRAKQAPR----PSFSTRNAGIE---AQDRRESLPTSPPWTPGASRPP 696 + +P+A + P PS + NA + A SL T P P A PP Sbjct: 930 PPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHP--PSAHPPP 987 Query: 697 SSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEARPPSRQLQAL 756 L P P P + ++ LPPPP P V+P +PP Q Sbjct: 988 LQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAP-------QPPFAQ---- 1036 Query: 757 LARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPARPGSAA-- 814 P G P P +PP P PP P S QP G+AA Sbjct: 1037 --------------HPFVPG--GPPPITPPTCPSTSTPPAGPG---TSAQPPCSGAAASG 1077 Query: 815 --VPGAAFAPIPRSPL-PAGPSSCTSPRSPLPAPPRPFLYRRSPTDSDVSLDSEDSGAKS 871 + G + P+P + P SP P P RSP+ +D+ ++S Sbjct: 1078 GSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPP-------RSPSPEPTVVDTPSHASQS 1130 Query: 872 PGIL-----GYNICPR 882 GYN C R Sbjct: 1131 ARFYKHLDRGYNSCAR 1146 Score = 46.2 bits (108), Expect = 1e-04 Identities = 82/369 (22%), Positives = 127/369 (34%), Gaps = 68/369 (18%) Query: 2 EGYSEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQNREAQQSSPAPPPAE 61 E S S R EKVAS+ EE K ++ + E + S E Sbjct: 639 EASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRP--NSPSEGEGESSDSRSVNDE 696 Query: 62 VHSPAADVNQNLASPSATLTTPTSNSSHNPPATD---VNQNPPATVVPQSLPLSSIQQNS 118 S D++Q+ S S ++ +P N S + + + PPA P + + Sbjct: 697 GSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPP 756 Query: 119 SEAQLPSNGTGPAS-------KPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTSTFS 171 QLP+ G P++ P+ A QPQAP A T Sbjct: 757 GTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----------------APVPHTHI 800 Query: 172 REATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLAK 231 ++A + RPP+ P+ Q ++G A Sbjct: 801 QQAPALHPQRPPSP---------HPPPHPSPHPPLQPLTGSAG----------------- 834 Query: 232 PPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSR 291 PS + P Q P G ++ P+L+ H G PQP LP ++ + Q + Sbjct: 835 QPSAPSHAQPPLHGQGPPGPHSLQAGPLLQ--HPG----PPQPFGLPPQASQGQAP-LGT 887 Query: 292 SPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLA-SWVRSPPSYSVLY---PSS 347 SP + PAS+ + P + L APLA ++ PP+ + P + Sbjct: 888 SPAAAYPHTSLQLPASQS---ALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQA 944 Query: 348 DPKSSHLKG 356 HL G Sbjct: 945 HKHPPHLSG 953 Score = 44.3 bits (103), Expect = 5e-04 Identities = 141/671 (21%), Positives = 224/671 (33%), Gaps = 143/671 (21%) Query: 44 LSQNREAQQSSPAPPPAEVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPAT 103 +S R ++ PA P + +N+++ S + S SS++ A V ++ Sbjct: 581 MSTLRSGRKKQPASPDGRT----SPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKV 636 Query: 104 VVPQSLPL-SSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAE---EVRCSTLLIDK 159 S PL S+ +Q A +SK + +P +P+E E S + D+ Sbjct: 637 KEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDE 696 Query: 160 VSTPATTTSTFSREAT-LIPSSRPPASDFMSSS--LLIDIQPNTL------VVSADQEMS 210 S+ +R + IPS + SD SS+ ++ QP L + Sbjct: 697 GSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPP 756 Query: 211 GRAAATTPTKVYSEVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAP 270 G TP S P+ +P AP + ++++P L ++ P Sbjct: 757 GTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH----PQRPP 812 Query: 271 APQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPL 330 +P PP P SP P ++ S GQ S S +P + PP +L PL Sbjct: 813 SPHPP--PHPSPHPPLQPLTGS-------AGQPSAPSHAQPPLHGQGPPG-PHSLQAGPL 862 Query: 331 ASWVRSPPSYSVLYPSSDPKSSHLKGQA-VPASKTGILEESMARRGSRKSMFTFVEKPKV 389 P + + P++S +GQA + S + + + +S + P+ Sbjct: 863 LQHPGPPQPFGL-----PPQAS--QGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPRE 915 Query: 390 TPNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVV 449 P P P + Q PAP+ P Sbjct: 916 QPLPP--------------------APLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPS 955 Query: 450 PEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCP 509 P + + P KP +LS S+H P L P Sbjct: 956 P----FSMNANLPPPPALKPLSSLSTHH-------------------PPSAHPPPLQLMP 992 Query: 510 SPTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRP 569 + LPSS P PG + + P PPAS P G+ + P QPP+ P Sbjct: 993 Q-SQPLPSS---PAQPPGLTQSQNLPP---PPAS-----HPPTGLHQVAP--QPPFAQHP 1038 Query: 570 SLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQ 629 VP P PP+ PS S+P PG Sbjct: 1039 ----------------------------FVPGGPPPITPPT----CPSTSTPP--AGPGT 1064 Query: 630 DSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWT 689 + P + + GG I+ S P P+ + ++ + ES P PP + Sbjct: 1065 SAQPPCSGAAASGGSIAGGS----------SCPLPTVQIKEEALDDAEEPES-PPPPPRS 1113 Query: 690 PGASRPPSSLD 700 P S P+ +D Sbjct: 1114 P--SPEPTVVD 1122 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 77.8 bits (190), Expect = 4e-14 Identities = 148/676 (21%), Positives = 231/676 (34%), Gaps = 122/676 (18%) Query: 263 RHFGEKAPAPQPPSLPDRSPRPQRH----IMSRSPMVERRMMGQRSPASERRPLGNFTAP 318 + +GE P +P P +P + + + M RR G S R A Sbjct: 537 KKYGELPPIEKPVDPPPFMFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRK--KQPAS 594 Query: 319 PTYTETLSTAPLASWVRSPPSYSVLYPSSDPKSSHLKGQAVPASKTGILEESMARRGSRK 378 P + + S R+ PS ++ S+ K + V S + EE+ + S K Sbjct: 595 PDGRTSPINEDIRSSGRNSPS------AASTSSNDSKAETVKKSAKKVKEEASSPLKSNK 648 Query: 379 SMFTFVEKPKVTPNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRD 438 ++ KV + + D + K ++ + E E + + + N + P+D Sbjct: 649 R-----QREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKD 703 Query: 439 RASPAAAEEVVPEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIES 498 + SP I P P+ N++ S++S + L A+ + + Sbjct: 704 IDQDNRST-----------SPSI---PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTP 749 Query: 499 --SSHTPELARCPSPTMSLPSSWKYPTNAPGAFRVASRSPARTPP--------ASLYHGY 548 SS P + P+P + ++ P +P A + ++ A T P A H Sbjct: 750 APSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQ 809 Query: 549 LPENGVLRPEPTKQPPYQ--------------LRPSLFVLSPI-KEPAKVSPRAASPAKP 593 P + P P+ PP Q +P L P + P P P Sbjct: 810 RPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPP 869 Query: 594 SSLDLVPNLPKGALP----PSPALPRPSRSSPGLYTS------PGQDSLQPTAVSPPYGG 643 L P +G P P+ A P S P ++ P + L P ++ P+ Sbjct: 870 QPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIK 929 Query: 644 DISPVSPSRAWSPRAKQAPR----PSFSTRNAGIE---AQDRRESLPTSPPWTPGASRPP 696 + +P+A + P PS + NA + A SL T P P A PP Sbjct: 930 PPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHP--PSAHPPP 987 Query: 697 SSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEARPPSRQLQAL 756 L P P P + ++ LPPPP P V+P +PP Q Sbjct: 988 LQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAP-------QPPFAQ---- 1036 Query: 757 LARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPARPGSAA-- 814 P G P P +PP P PP P S QP G+AA Sbjct: 1037 --------------HPFVPG--GPPPITPPTCPSTSTPPAGPG---TSAQPPCSGAAASG 1077 Query: 815 --VPGAAFAPIPRSPL-PAGPSSCTSPRSPLPAPPRPFLYRRSPTDSDVSLDSEDSGAKS 871 + G + P+P + P SP P P RSP+ +D+ ++S Sbjct: 1078 GSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPP-------RSPSPEPTVVDTPSHASQS 1130 Query: 872 PGIL-----GYNICPR 882 GYN C R Sbjct: 1131 ARFYKHLDRGYNSCAR 1146 Score = 46.2 bits (108), Expect = 1e-04 Identities = 82/369 (22%), Positives = 127/369 (34%), Gaps = 68/369 (18%) Query: 2 EGYSEEASLLRHLEKVASEEEEVPLVVYLKENAALLTANGLHLSQNREAQQSSPAPPPAE 61 E S S R EKVAS+ EE K ++ + E + S E Sbjct: 639 EASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRP--NSPSEGEGESSDSRSVNDE 696 Query: 62 VHSPAADVNQNLASPSATLTTPTSNSSHNPPATD---VNQNPPATVVPQSLPLSSIQQNS 118 S D++Q+ S S ++ +P N S + + + PPA P + + Sbjct: 697 GSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPP 756 Query: 119 SEAQLPSNGTGPAS-------KPSTLCADGQPQAPAEEVRCSTLLIDKVSTPATTTSTFS 171 QLP+ G P++ P+ A QPQAP A T Sbjct: 757 GTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPT----------------APVPHTHI 800 Query: 172 REATLIPSSRPPASDFMSSSLLIDIQPNTLVVSADQEMSGRAAATTPTKVYSEVHFTLAK 231 ++A + RPP+ P+ Q ++G A Sbjct: 801 QQAPALHPQRPPSP---------HPPPHPSPHPPLQPLTGSAG----------------- 834 Query: 232 PPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAPAPQPPSLPDRSPRPQRHIMSR 291 PS + P Q P G ++ P+L+ H G PQP LP ++ + Q + Sbjct: 835 QPSAPSHAQPPLHGQGPPGPHSLQAGPLLQ--HPG----PPQPFGLPPQASQGQAP-LGT 887 Query: 292 SPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPLA-SWVRSPPSYSVLY---PSS 347 SP + PAS+ + P + L APLA ++ PP+ + P + Sbjct: 888 SPAAAYPHTSLQLPASQS---ALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQA 944 Query: 348 DPKSSHLKG 356 HL G Sbjct: 945 HKHPPHLSG 953 Score = 44.3 bits (103), Expect = 5e-04 Identities = 141/671 (21%), Positives = 224/671 (33%), Gaps = 143/671 (21%) Query: 44 LSQNREAQQSSPAPPPAEVHSPAADVNQNLASPSATLTTPTSNSSHNPPATDVNQNPPAT 103 +S R ++ PA P + +N+++ S + S SS++ A V ++ Sbjct: 581 MSTLRSGRKKQPASPDGRT----SPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKV 636 Query: 104 VVPQSLPL-SSIQQNSSEAQLPSNGTGPASKPSTLCADGQPQAPAE---EVRCSTLLIDK 159 S PL S+ +Q A +SK + +P +P+E E S + D+ Sbjct: 637 KEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDE 696 Query: 160 VSTPATTTSTFSREAT-LIPSSRPPASDFMSSS--LLIDIQPNTL------VVSADQEMS 210 S+ +R + IPS + SD SS+ ++ QP L + Sbjct: 697 GSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPP 756 Query: 211 GRAAATTPTKVYSEVHFTLAKPPSVVNRTARPFGIQAPGGTSQMERSPMLERRHFGEKAP 270 G TP S P+ +P AP + ++++P L ++ P Sbjct: 757 GTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH----PQRPP 812 Query: 271 APQPPSLPDRSPRPQRHIMSRSPMVERRMMGQRSPASERRPLGNFTAPPTYTETLSTAPL 330 +P PP P SP P ++ S GQ S S +P + PP +L PL Sbjct: 813 SPHPP--PHPSPHPPLQPLTGS-------AGQPSAPSHAQPPLHGQGPPG-PHSLQAGPL 862 Query: 331 ASWVRSPPSYSVLYPSSDPKSSHLKGQA-VPASKTGILEESMARRGSRKSMFTFVEKPKV 389 P + + P++S +GQA + S + + + +S + P+ Sbjct: 863 LQHPGPPQPFGL-----PPQAS--QGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPRE 915 Query: 390 TPNPDLLDLVQTADEKRRQRDQGEVGVEEEPFALGAEASNFQQEPAPRDRASPAAAEEVV 449 P P P + Q PAP+ P Sbjct: 916 QPLPP--------------------APLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPS 955 Query: 450 PEWASCLKSPRIQAKPKPKPNQNLSEASGKGAELYARRQSRMEKYVIESSSHTPELARCP 509 P + + P KP +LS S+H P L P Sbjct: 956 P----FSMNANLPPPPALKPLSSLSTHH-------------------PPSAHPPPLQLMP 992 Query: 510 SPTMSLPSSWKYPTNAPGAFRVASRSPARTPPASLYHGYLPENGVLRPEPTKQPPYQLRP 569 + LPSS P PG + + P PPAS P G+ + P QPP+ P Sbjct: 993 Q-SQPLPSS---PAQPPGLTQSQNLPP---PPAS-----HPPTGLHQVAP--QPPFAQHP 1038 Query: 570 SLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPRPSRSSPGLYTSPGQ 629 VP P PP+ PS S+P PG Sbjct: 1039 ----------------------------FVPGGPPPITPPT----CPSTSTPP--AGPGT 1064 Query: 630 DSLQPTAVSPPYGGDISPVSPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWT 689 + P + + GG I+ S P P+ + ++ + ES P PP + Sbjct: 1065 SAQPPCSGAAASGGSIAGGS----------SCPLPTVQIKEEALDDAEEPES-PPPPPRS 1113 Query: 690 PGASRPPSSLD 700 P S P+ +D Sbjct: 1114 P--SPEPTVVD 1122 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.309 0.126 0.377 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 51,982,991 Number of Sequences: 37866 Number of extensions: 3848844 Number of successful extensions: 87223 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 1172 Number of HSP's successfully gapped in prelim test: 2241 Number of HSP's that attempted gapping in prelim test: 22849 Number of HSP's gapped (non-prelim): 26495 length of query: 903 length of database: 18,247,518 effective HSP length: 111 effective length of query: 792 effective length of database: 14,044,392 effective search space: 11123158464 effective search space used: 11123158464 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.