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Search of human proteins with 40316939
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40316939 5-aminolevulinate synthase 1 [Homo sapiens]
(640 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40316939 5-aminolevulinate synthase 1 [Homo sapiens] 1288 0.0
gi|4502025 5-aminolevulinate synthase 1 [Homo sapiens] 1288 0.0
gi|83977442 5-aminolevulinate synthase 2 isoform a precursor [Ho... 713 0.0
gi|83977444 5-aminolevulinate synthase 2 isoform c precursor [Ho... 687 0.0
gi|83977440 5-aminolevulinate synthase 2 isoform b precursor [Ho... 687 0.0
gi|7657118 glycine C-acetyltransferase precursor [Homo sapiens] 204 2e-52
gi|4758668 serine palmitoyltransferase, long chain base subunit ... 156 5e-38
gi|119220554 serine palmitoyltransferase, long chain base subuni... 144 2e-34
gi|5454084 serine palmitoyltransferase subunit 1 isoform a [Homo... 127 4e-29
gi|30474871 serine palmitoyltransferase subunit 1 isoform b [Hom... 34 0.36
gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens] 34 0.36
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 33 0.62
gi|42716289 erythrocyte membrane protein band 4.1 (elliptocytosi... 33 1.1
gi|150170670 piccolo isoform 2 [Homo sapiens] 33 1.1
gi|150378539 piccolo isoform 1 [Homo sapiens] 33 1.1
gi|71725360 zinc finger protein 609 [Homo sapiens] 32 2.3
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 31 3.1
gi|13899233 tetratricopeptide repeat domain 25 [Homo sapiens] 31 3.1
gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo ... 31 4.0
gi|125625322 RALBP1 associated Eps domain containing 2 isoform 2... 31 4.0
gi|125625326 RALBP1 associated Eps domain containing 2 isoform 1... 31 4.0
gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo ... 31 4.0
gi|29244924 chromodomain helicase DNA binding protein 6 [Homo sa... 31 4.0
gi|163965366 nascent polypeptide-associated complex alpha subuni... 31 4.0
gi|21536357 TBP-associated factor 6 isoform delta [Homo sapiens] 30 5.2
gi|21536355 TBP-associated factor 6 isoform gamma [Homo sapiens] 30 5.2
gi|5032147 TBP-associated factor 6 isoform alpha [Homo sapiens] 30 5.2
gi|21536359 TBP-associated factor 6 isoform alpha [Homo sapiens] 30 5.2
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s... 30 5.2
gi|56549694 enabled homolog isoform a [Homo sapiens] 30 6.8
>gi|40316939 5-aminolevulinate synthase 1 [Homo sapiens]
Length = 640
Score = 1288 bits (3333), Expect = 0.0
Identities = 640/640 (100%), Positives = 640/640 (100%)
Query: 1 MESVVRRCPFLSRVPQAFLQKAGKSLLFYAQNCPKMMEVGAKPAPRALSTAAVHYQQIKE 60
MESVVRRCPFLSRVPQAFLQKAGKSLLFYAQNCPKMMEVGAKPAPRALSTAAVHYQQIKE
Sbjct: 1 MESVVRRCPFLSRVPQAFLQKAGKSLLFYAQNCPKMMEVGAKPAPRALSTAAVHYQQIKE 60
Query: 61 TPPASEKDKTAKAKVQQTPDGSQQSPDGTQLPSGHPLPATSQGTASKCPFLAAQMNQRGS 120
TPPASEKDKTAKAKVQQTPDGSQQSPDGTQLPSGHPLPATSQGTASKCPFLAAQMNQRGS
Sbjct: 61 TPPASEKDKTAKAKVQQTPDGSQQSPDGTQLPSGHPLPATSQGTASKCPFLAAQMNQRGS 120
Query: 121 SVFCKASLELQEDVQEMNAVRKEVAETSAGPSVVSVKTDGGDPSGLLKNFQDIMQKQRPE 180
SVFCKASLELQEDVQEMNAVRKEVAETSAGPSVVSVKTDGGDPSGLLKNFQDIMQKQRPE
Sbjct: 121 SVFCKASLELQEDVQEMNAVRKEVAETSAGPSVVSVKTDGGDPSGLLKNFQDIMQKQRPE 180
Query: 181 RVSHLLQDNLPKSVSTFQYDRFFEKKIDEKKNDHTYRVFKTVNRRAHIFPMADDYSDSLI 240
RVSHLLQDNLPKSVSTFQYDRFFEKKIDEKKNDHTYRVFKTVNRRAHIFPMADDYSDSLI
Sbjct: 181 RVSHLLQDNLPKSVSTFQYDRFFEKKIDEKKNDHTYRVFKTVNRRAHIFPMADDYSDSLI 240
Query: 241 TKKQVSVWCSNDYLGMSRHPRVCGAVMDTLKQHGAGAGGTRNISGTSKFHVDLERELADL 300
TKKQVSVWCSNDYLGMSRHPRVCGAVMDTLKQHGAGAGGTRNISGTSKFHVDLERELADL
Sbjct: 241 TKKQVSVWCSNDYLGMSRHPRVCGAVMDTLKQHGAGAGGTRNISGTSKFHVDLERELADL 300
Query: 301 HGKDAALLFSSCFVANDSTLFTLAKMMPGCEIYSDSGNHASMIQGIRNSRVPKYIFRHND 360
HGKDAALLFSSCFVANDSTLFTLAKMMPGCEIYSDSGNHASMIQGIRNSRVPKYIFRHND
Sbjct: 301 HGKDAALLFSSCFVANDSTLFTLAKMMPGCEIYSDSGNHASMIQGIRNSRVPKYIFRHND 360
Query: 361 VSHLRELLQRSDPSVPKIVAFETVHSMDGAVCPLEELCDVAHEFGAITFVDEVHAVGLYG 420
VSHLRELLQRSDPSVPKIVAFETVHSMDGAVCPLEELCDVAHEFGAITFVDEVHAVGLYG
Sbjct: 361 VSHLRELLQRSDPSVPKIVAFETVHSMDGAVCPLEELCDVAHEFGAITFVDEVHAVGLYG 420
Query: 421 ARGGGIGDRDGVMPKMDIISGTLGKAFGCVGGYIASTSSLIDTVRSYAAGFIFTTSLPPM 480
ARGGGIGDRDGVMPKMDIISGTLGKAFGCVGGYIASTSSLIDTVRSYAAGFIFTTSLPPM
Sbjct: 421 ARGGGIGDRDGVMPKMDIISGTLGKAFGCVGGYIASTSSLIDTVRSYAAGFIFTTSLPPM 480
Query: 481 LLAGALESVRILKSAEGRVLRRQHQRNVKLMRQMLMDAGLPVVHCPSHIIPVRVADAAKN 540
LLAGALESVRILKSAEGRVLRRQHQRNVKLMRQMLMDAGLPVVHCPSHIIPVRVADAAKN
Sbjct: 481 LLAGALESVRILKSAEGRVLRRQHQRNVKLMRQMLMDAGLPVVHCPSHIIPVRVADAAKN 540
Query: 541 TEVCDELMSRHNIYVQAINYPTVPRGEELLRIAPTPHHTPQMMNYFLENLLVTWKQVGLE 600
TEVCDELMSRHNIYVQAINYPTVPRGEELLRIAPTPHHTPQMMNYFLENLLVTWKQVGLE
Sbjct: 541 TEVCDELMSRHNIYVQAINYPTVPRGEELLRIAPTPHHTPQMMNYFLENLLVTWKQVGLE 600
Query: 601 LKPHSSAECNFCRRPLHFEVMSEREKSYFSGLSKLVSAQA 640
LKPHSSAECNFCRRPLHFEVMSEREKSYFSGLSKLVSAQA
Sbjct: 601 LKPHSSAECNFCRRPLHFEVMSEREKSYFSGLSKLVSAQA 640
>gi|4502025 5-aminolevulinate synthase 1 [Homo sapiens]
Length = 640
Score = 1288 bits (3333), Expect = 0.0
Identities = 640/640 (100%), Positives = 640/640 (100%)
Query: 1 MESVVRRCPFLSRVPQAFLQKAGKSLLFYAQNCPKMMEVGAKPAPRALSTAAVHYQQIKE 60
MESVVRRCPFLSRVPQAFLQKAGKSLLFYAQNCPKMMEVGAKPAPRALSTAAVHYQQIKE
Sbjct: 1 MESVVRRCPFLSRVPQAFLQKAGKSLLFYAQNCPKMMEVGAKPAPRALSTAAVHYQQIKE 60
Query: 61 TPPASEKDKTAKAKVQQTPDGSQQSPDGTQLPSGHPLPATSQGTASKCPFLAAQMNQRGS 120
TPPASEKDKTAKAKVQQTPDGSQQSPDGTQLPSGHPLPATSQGTASKCPFLAAQMNQRGS
Sbjct: 61 TPPASEKDKTAKAKVQQTPDGSQQSPDGTQLPSGHPLPATSQGTASKCPFLAAQMNQRGS 120
Query: 121 SVFCKASLELQEDVQEMNAVRKEVAETSAGPSVVSVKTDGGDPSGLLKNFQDIMQKQRPE 180
SVFCKASLELQEDVQEMNAVRKEVAETSAGPSVVSVKTDGGDPSGLLKNFQDIMQKQRPE
Sbjct: 121 SVFCKASLELQEDVQEMNAVRKEVAETSAGPSVVSVKTDGGDPSGLLKNFQDIMQKQRPE 180
Query: 181 RVSHLLQDNLPKSVSTFQYDRFFEKKIDEKKNDHTYRVFKTVNRRAHIFPMADDYSDSLI 240
RVSHLLQDNLPKSVSTFQYDRFFEKKIDEKKNDHTYRVFKTVNRRAHIFPMADDYSDSLI
Sbjct: 181 RVSHLLQDNLPKSVSTFQYDRFFEKKIDEKKNDHTYRVFKTVNRRAHIFPMADDYSDSLI 240
Query: 241 TKKQVSVWCSNDYLGMSRHPRVCGAVMDTLKQHGAGAGGTRNISGTSKFHVDLERELADL 300
TKKQVSVWCSNDYLGMSRHPRVCGAVMDTLKQHGAGAGGTRNISGTSKFHVDLERELADL
Sbjct: 241 TKKQVSVWCSNDYLGMSRHPRVCGAVMDTLKQHGAGAGGTRNISGTSKFHVDLERELADL 300
Query: 301 HGKDAALLFSSCFVANDSTLFTLAKMMPGCEIYSDSGNHASMIQGIRNSRVPKYIFRHND 360
HGKDAALLFSSCFVANDSTLFTLAKMMPGCEIYSDSGNHASMIQGIRNSRVPKYIFRHND
Sbjct: 301 HGKDAALLFSSCFVANDSTLFTLAKMMPGCEIYSDSGNHASMIQGIRNSRVPKYIFRHND 360
Query: 361 VSHLRELLQRSDPSVPKIVAFETVHSMDGAVCPLEELCDVAHEFGAITFVDEVHAVGLYG 420
VSHLRELLQRSDPSVPKIVAFETVHSMDGAVCPLEELCDVAHEFGAITFVDEVHAVGLYG
Sbjct: 361 VSHLRELLQRSDPSVPKIVAFETVHSMDGAVCPLEELCDVAHEFGAITFVDEVHAVGLYG 420
Query: 421 ARGGGIGDRDGVMPKMDIISGTLGKAFGCVGGYIASTSSLIDTVRSYAAGFIFTTSLPPM 480
ARGGGIGDRDGVMPKMDIISGTLGKAFGCVGGYIASTSSLIDTVRSYAAGFIFTTSLPPM
Sbjct: 421 ARGGGIGDRDGVMPKMDIISGTLGKAFGCVGGYIASTSSLIDTVRSYAAGFIFTTSLPPM 480
Query: 481 LLAGALESVRILKSAEGRVLRRQHQRNVKLMRQMLMDAGLPVVHCPSHIIPVRVADAAKN 540
LLAGALESVRILKSAEGRVLRRQHQRNVKLMRQMLMDAGLPVVHCPSHIIPVRVADAAKN
Sbjct: 481 LLAGALESVRILKSAEGRVLRRQHQRNVKLMRQMLMDAGLPVVHCPSHIIPVRVADAAKN 540
Query: 541 TEVCDELMSRHNIYVQAINYPTVPRGEELLRIAPTPHHTPQMMNYFLENLLVTWKQVGLE 600
TEVCDELMSRHNIYVQAINYPTVPRGEELLRIAPTPHHTPQMMNYFLENLLVTWKQVGLE
Sbjct: 541 TEVCDELMSRHNIYVQAINYPTVPRGEELLRIAPTPHHTPQMMNYFLENLLVTWKQVGLE 600
Query: 601 LKPHSSAECNFCRRPLHFEVMSEREKSYFSGLSKLVSAQA 640
LKPHSSAECNFCRRPLHFEVMSEREKSYFSGLSKLVSAQA
Sbjct: 601 LKPHSSAECNFCRRPLHFEVMSEREKSYFSGLSKLVSAQA 640
>gi|83977442 5-aminolevulinate synthase 2 isoform a precursor [Homo
sapiens]
Length = 587
Score = 713 bits (1840), Expect = 0.0
Identities = 357/557 (64%), Positives = 438/557 (78%), Gaps = 23/557 (4%)
Query: 77 QTPDGSQQSPDGTQLPSGHPLPATSQGTASKCPFLAAQMNQRGSSVFCKASLELQEDVQE 136
Q P+ SQ T+ +G P+ ++G CPF+ +++ S + KA+ E+QEDV+
Sbjct: 44 QGPNCSQIHLKATK--AGGDSPSWAKG---HCPFMLSELQDGKSKIVQKAAPEVQEDVKA 98
Query: 137 MNAVRKEVAETSAGPSVVSVKTDGGDPSGLLKNFQDIM-QKQRPERVSHLLQDNLPKSVS 195
+T S+VSV L K F Q+Q +V+HL+Q+N+P +
Sbjct: 99 F--------KTDLPSSLVSVS--------LRKPFSGPQEQEQISGKVTHLIQNNMPGNY- 141
Query: 196 TFQYDRFFEKKIDEKKNDHTYRVFKTVNRRAHIFPMADDYSDSLITKKQVSVWCSNDYLG 255
F YD+FF KI EKK DHTYRVFKTVNR A +P A +S++ + K VSVWCSNDYLG
Sbjct: 142 VFSYDQFFRDKIMEKKQDHTYRVFKTVNRWADAYPFAQHFSEASVASKDVSVWCSNDYLG 201
Query: 256 MSRHPRVCGAVMDTLKQHGAGAGGTRNISGTSKFHVDLERELADLHGKDAALLFSSCFVA 315
MSRHP+V A +TL++HGAGAGGTRNISGTSKFHV+LE+ELA+LH KD+ALLFSSCFVA
Sbjct: 202 MSRHPQVLQATQETLQRHGAGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVA 261
Query: 316 NDSTLFTLAKMMPGCEIYSDSGNHASMIQGIRNSRVPKYIFRHNDVSHLRELLQRSDPSV 375
NDSTLFTLAK++PGCEIYSD+GNHASMIQGIRNS K++FRHND HL++LL++S+P +
Sbjct: 262 NDSTLFTLAKILPGCEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKLLEKSNPKI 321
Query: 376 PKIVAFETVHSMDGAVCPLEELCDVAHEFGAITFVDEVHAVGLYGARGGGIGDRDGVMPK 435
PKIVAFETVHSMDGA+CPLEELCDV+H++GA+TFVDEVHAVGLYG+RG GIG+RDG+M K
Sbjct: 322 PKIVAFETVHSMDGAICPLEELCDVSHQYGALTFVDEVHAVGLYGSRGAGIGERDGIMHK 381
Query: 436 MDIISGTLGKAFGCVGGYIASTSSLIDTVRSYAAGFIFTTSLPPMLLAGALESVRILKSA 495
+DIISGTLGKAFGCVGGYIAST L+D VRSYAAGFIFTTSLPPM+L+GALESVR+LK
Sbjct: 382 IDIISGTLGKAFGCVGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGE 441
Query: 496 EGRVLRRQHQRNVKLMRQMLMDAGLPVVHCPSHIIPVRVADAAKNTEVCDELMSRHNIYV 555
EG+ LRR HQRNVK MRQ+LMD GLPV+ CPSHIIP+RV +AA N+++CD L+S+H IYV
Sbjct: 442 EGQALRRAHQRNVKHMRQLLMDRGLPVIPCPSHIIPIRVGNAALNSKLCDLLLSKHGIYV 501
Query: 556 QAINYPTVPRGEELLRIAPTPHHTPQMMNYFLENLLVTWKQVGLELKPHSSAECNFCRRP 615
QAINYPTVPRGEELLR+AP+PHH+PQMM F+E LL+ W VGL L+ S A CNFCRRP
Sbjct: 502 QAINYPTVPRGEELLRLAPSPHHSPQMMEDFVEKLLLAWTAVGLPLQDVSVAACNFCRRP 561
Query: 616 LHFEVMSEREKSYFSGL 632
+HFE+MSE E+SYF +
Sbjct: 562 VHFELMSEWERSYFGNM 578
>gi|83977444 5-aminolevulinate synthase 2 isoform c precursor [Homo
sapiens]
Length = 574
Score = 687 bits (1773), Expect = 0.0
Identities = 332/483 (68%), Positives = 395/483 (81%), Gaps = 10/483 (2%)
Query: 160 GGDPSGLLKNFQDIMQKQRPERVSHLLQDNLP------KSVST----FQYDRFFEKKIDE 209
GGD K M + + S ++Q P K+ T F YD+FF KI E
Sbjct: 83 GGDSPSWAKGHCPFMLSELQDGKSKIVQKAAPEVQEDVKAFKTGNYVFSYDQFFRDKIME 142
Query: 210 KKNDHTYRVFKTVNRRAHIFPMADDYSDSLITKKQVSVWCSNDYLGMSRHPRVCGAVMDT 269
KK DHTYRVFKTVNR A +P A +S++ + K VSVWCSNDYLGMSRHP+V A +T
Sbjct: 143 KKQDHTYRVFKTVNRWADAYPFAQHFSEASVASKDVSVWCSNDYLGMSRHPQVLQATQET 202
Query: 270 LKQHGAGAGGTRNISGTSKFHVDLERELADLHGKDAALLFSSCFVANDSTLFTLAKMMPG 329
L++HGAGAGGTRNISGTSKFHV+LE+ELA+LH KD+ALLFSSCFVANDSTLFTLAK++PG
Sbjct: 203 LQRHGAGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVANDSTLFTLAKILPG 262
Query: 330 CEIYSDSGNHASMIQGIRNSRVPKYIFRHNDVSHLRELLQRSDPSVPKIVAFETVHSMDG 389
CEIYSD+GNHASMIQGIRNS K++FRHND HL++LL++S+P +PKIVAFETVHSMDG
Sbjct: 263 CEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKLLEKSNPKIPKIVAFETVHSMDG 322
Query: 390 AVCPLEELCDVAHEFGAITFVDEVHAVGLYGARGGGIGDRDGVMPKMDIISGTLGKAFGC 449
A+CPLEELCDV+H++GA+TFVDEVHAVGLYG+RG GIG+RDG+M K+DIISGTLGKAFGC
Sbjct: 323 AICPLEELCDVSHQYGALTFVDEVHAVGLYGSRGAGIGERDGIMHKIDIISGTLGKAFGC 382
Query: 450 VGGYIASTSSLIDTVRSYAAGFIFTTSLPPMLLAGALESVRILKSAEGRVLRRQHQRNVK 509
VGGYIAST L+D VRSYAAGFIFTTSLPPM+L+GALESVR+LK EG+ LRR HQRNVK
Sbjct: 383 VGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVK 442
Query: 510 LMRQMLMDAGLPVVHCPSHIIPVRVADAAKNTEVCDELMSRHNIYVQAINYPTVPRGEEL 569
MRQ+LMD GLPV+ CPSHIIP+RV +AA N+++CD L+S+H IYVQAINYPTVPRGEEL
Sbjct: 443 HMRQLLMDRGLPVIPCPSHIIPIRVGNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEEL 502
Query: 570 LRIAPTPHHTPQMMNYFLENLLVTWKQVGLELKPHSSAECNFCRRPLHFEVMSEREKSYF 629
LR+AP+PHH+PQMM F+E LL+ W VGL L+ S A CNFCRRP+HFE+MSE E+SYF
Sbjct: 503 LRLAPSPHHSPQMMEDFVEKLLLAWTAVGLPLQDVSVAACNFCRRPVHFELMSEWERSYF 562
Query: 630 SGL 632
+
Sbjct: 563 GNM 565
>gi|83977440 5-aminolevulinate synthase 2 isoform b precursor [Homo
sapiens]
Length = 550
Score = 687 bits (1773), Expect = 0.0
Identities = 332/483 (68%), Positives = 395/483 (81%), Gaps = 10/483 (2%)
Query: 160 GGDPSGLLKNFQDIMQKQRPERVSHLLQDNLP------KSVST----FQYDRFFEKKIDE 209
GGD K M + + S ++Q P K+ T F YD+FF KI E
Sbjct: 59 GGDSPSWAKGHCPFMLSELQDGKSKIVQKAAPEVQEDVKAFKTGNYVFSYDQFFRDKIME 118
Query: 210 KKNDHTYRVFKTVNRRAHIFPMADDYSDSLITKKQVSVWCSNDYLGMSRHPRVCGAVMDT 269
KK DHTYRVFKTVNR A +P A +S++ + K VSVWCSNDYLGMSRHP+V A +T
Sbjct: 119 KKQDHTYRVFKTVNRWADAYPFAQHFSEASVASKDVSVWCSNDYLGMSRHPQVLQATQET 178
Query: 270 LKQHGAGAGGTRNISGTSKFHVDLERELADLHGKDAALLFSSCFVANDSTLFTLAKMMPG 329
L++HGAGAGGTRNISGTSKFHV+LE+ELA+LH KD+ALLFSSCFVANDSTLFTLAK++PG
Sbjct: 179 LQRHGAGAGGTRNISGTSKFHVELEQELAELHQKDSALLFSSCFVANDSTLFTLAKILPG 238
Query: 330 CEIYSDSGNHASMIQGIRNSRVPKYIFRHNDVSHLRELLQRSDPSVPKIVAFETVHSMDG 389
CEIYSD+GNHASMIQGIRNS K++FRHND HL++LL++S+P +PKIVAFETVHSMDG
Sbjct: 239 CEIYSDAGNHASMIQGIRNSGAAKFVFRHNDPDHLKKLLEKSNPKIPKIVAFETVHSMDG 298
Query: 390 AVCPLEELCDVAHEFGAITFVDEVHAVGLYGARGGGIGDRDGVMPKMDIISGTLGKAFGC 449
A+CPLEELCDV+H++GA+TFVDEVHAVGLYG+RG GIG+RDG+M K+DIISGTLGKAFGC
Sbjct: 299 AICPLEELCDVSHQYGALTFVDEVHAVGLYGSRGAGIGERDGIMHKIDIISGTLGKAFGC 358
Query: 450 VGGYIASTSSLIDTVRSYAAGFIFTTSLPPMLLAGALESVRILKSAEGRVLRRQHQRNVK 509
VGGYIAST L+D VRSYAAGFIFTTSLPPM+L+GALESVR+LK EG+ LRR HQRNVK
Sbjct: 359 VGGYIASTRDLVDMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEGQALRRAHQRNVK 418
Query: 510 LMRQMLMDAGLPVVHCPSHIIPVRVADAAKNTEVCDELMSRHNIYVQAINYPTVPRGEEL 569
MRQ+LMD GLPV+ CPSHIIP+RV +AA N+++CD L+S+H IYVQAINYPTVPRGEEL
Sbjct: 419 HMRQLLMDRGLPVIPCPSHIIPIRVGNAALNSKLCDLLLSKHGIYVQAINYPTVPRGEEL 478
Query: 570 LRIAPTPHHTPQMMNYFLENLLVTWKQVGLELKPHSSAECNFCRRPLHFEVMSEREKSYF 629
LR+AP+PHH+PQMM F+E LL+ W VGL L+ S A CNFCRRP+HFE+MSE E+SYF
Sbjct: 479 LRLAPSPHHSPQMMEDFVEKLLLAWTAVGLPLQDVSVAACNFCRRPVHFELMSEWERSYF 538
Query: 630 SGL 632
+
Sbjct: 539 GNM 541
>gi|7657118 glycine C-acetyltransferase precursor [Homo sapiens]
Length = 419
Score = 204 bits (519), Expect = 2e-52
Identities = 117/342 (34%), Positives = 190/342 (55%), Gaps = 6/342 (1%)
Query: 248 WCSNDYLGMSRHPRVCGAVMDTLKQHGAGAGGTRNISGTSKFHVDLERELADLHGKDAAL 307
+C+N+YLG+S HP V A + L++ GAG R I GT H +LE ++A H ++ A+
Sbjct: 70 FCANNYLGLSSHPEVIQAGLQALEEFGAGLSSVRFICGTQSIHKNLEAKIARFHQREDAI 129
Query: 308 LFSSCFVANDSTLFTLAKMMPGCEIYSDSGNHASMIQGIRNSRVPKYIFRHNDVSHLREL 367
L+ SC+ AN + LF A + P + SD NHAS+I GIR + KY +RH D++ L
Sbjct: 130 LYPSCYDAN-AGLFE-ALLTPEDAVLSDELNHASIIDGIRLCKAHKYRYRHLDMADLEAK 187
Query: 368 LQRSDPSVPKIVAFETVHSMDGAVCPLEELCDVAHEFGAITFVDEVHAVGLYGARGGGIG 427
LQ + ++VA + SMDG + PL+E+C +A +GA+ F+DE HA G G G G
Sbjct: 188 LQEAQKHRLRLVATDGAFSMDGDIAPLQEICCLASRYGALVFMDECHATGFLGPTGRGTD 247
Query: 428 DRDGVMPKMDIISGTLGKAF-GCVGGYIASTSSLIDTVRSYAAGFIFTTSLPPMLLAGAL 486
+ GVM ++ II+ TLGKA G GGY L+ +R A ++F+ SLPP ++ A
Sbjct: 248 ELLGVMDQVTIINSTLGKALGGASGGYTTGPGPLVSLLRQRARPYLFSNSLPPAVVGCAS 307
Query: 487 ESVRILKSAEGRVLRRQHQRNVKLMRQMLMDAGLPVVHCPSHIIPVRVADAAKNTEVCDE 546
+++ +L + + + + R + AG + I PV + DA + + D+
Sbjct: 308 KALDLLMGS--NTIVQSMAAKTQRFRSKMEAAGFTISGASHPICPVMLGDARLASRMADD 365
Query: 547 LMSRHNIYVQAINYPTVPRGEELLRIAPTPHHTPQMMNYFLE 588
++ R I+V +YP VP+G+ +R+ + H+ + ++ +E
Sbjct: 366 MLKR-GIFVIGFSYPVVPKGKARIRVQISAVHSEEDIDRCVE 406
>gi|4758668 serine palmitoyltransferase, long chain base subunit 2
[Homo sapiens]
Length = 562
Score = 156 bits (395), Expect = 5e-38
Identities = 128/469 (27%), Positives = 229/469 (48%), Gaps = 36/469 (7%)
Query: 151 PSVVSVKTDGGDPSGLLKNF---QDIMQKQRPERVSHLLQDNLPKS-VSTFQ-YDRFFEK 205
P +V+V T G G+L F +D ++ R E+ H + K VS +Q ++ F+ +
Sbjct: 67 PMLVAVLTYVG--YGVLTLFGYLRDFLRYWRIEKCHHATEREEQKDFVSLYQDFENFYTR 124
Query: 206 KIDEKKNDHTYRVFKTV--------NRRAHIFPMADDYSDSLITKKQVSVWCSNDYLGMS 257
+ + D+ R +V R++H + + Y+ ++I K V S +YLG +
Sbjct: 125 NLYMRIRDNWNRPICSVPGARVDIMERQSHDYNWSFKYTGNII--KGVINMGSYNYLGFA 182
Query: 258 RHPRVCG-AVMDTLKQHGAGAGGTRNISGTSKFHVDLERELADLHGKDAALLFSSCFVAN 316
R+ C A L+++GAG TR G H +LE +A G +AA+ + F N
Sbjct: 183 RNTGSCQEAAAKVLEEYGAGVCSTRQEIGNLDKHEELEELVARFLGVEAAMAYGMGFATN 242
Query: 317 DSTLFTLAKMMPGCEIYSDSGNHASMIQGIRNSRVPKYIFRHNDVSHLRELLQRS----- 371
+ L GC I SD NHAS++ G R S IF+HN++ L +LL+ +
Sbjct: 243 SMNIPALVGK--GCLILSDELNHASLVLGARLSGATIRIFKHNNMQSLEKLLKDAIVYGQ 300
Query: 372 ----DPSVPKIVAFETVHSMDGAVCPLEELCDVAHEFGAITFVDEVHAVGLYGARGGGIG 427
P ++ E ++SM+G++ L E+ + ++ A ++DE H++G G G G+
Sbjct: 301 PRTRRPWKKILILVEGIYSMEGSIVRLPEVIALKKKYKAYLYLDEAHSIGALGPTGRGVV 360
Query: 428 DRDGVMPK-MDIISGTLGKAFGCVGGYIASTSSLIDTVRSYAAGFIFTTSLPPMLLAGAL 486
+ G+ P+ +D++ GT K+FG GGYI LID +R+++ ++ TSL P ++ +
Sbjct: 361 EYFGLDPEDVDVMMGTFTKSFGASGGYIGGKKELIDYLRTHSHSAVYATSLSPPVVEQII 420
Query: 487 ESVRILKSAEGRVLRR----QHQRNVKLMRQMLMDAGLPVV-HCPSHIIPVRVADAAKNT 541
S++ + +G L + Q N + R+ L + G + + S ++P+ + AK
Sbjct: 421 TSMKCIMGQDGTSLGKECVQQLAENTRYFRRRLKEMGFIIYGNEDSPVVPLMLYMPAKIG 480
Query: 542 EVCDELMSRHNIYVQAINYPTVPRGEELLRIAPTPHHTPQMMNYFLENL 590
E++ R NI V + +P P E R + HT ++++ L+ +
Sbjct: 481 AFGREMLKR-NIGVVVVGFPATPIIESRARFCLSAAHTKEILDTALKEI 528
>gi|119220554 serine palmitoyltransferase, long chain base subunit 3
[Homo sapiens]
Length = 552
Score = 144 bits (363), Expect = 2e-34
Identities = 98/357 (27%), Positives = 179/357 (50%), Gaps = 19/357 (5%)
Query: 250 SNDYLGMS-RHPRVCGAVMDTLKQHGAGAGGTRNISGTSKFHVDLERELADLHGKDAALL 308
S ++LG++ ++ + D L+ +G G TR+ GT H +LE +A +AA++
Sbjct: 167 SYNFLGLAAKYDESMRTIKDVLEVYGTGVASTRHEMGTLDKHKELEDLVAKFLNVEAAMV 226
Query: 309 FSSCFVANDSTLFTLAKMMPGCEIYSDSGNHASMIQGIRNSRVPKYIFRHNDVSHLRELL 368
F F N + L GC I SD NH S++ G R S IF+HN+ L +LL
Sbjct: 227 FGMGFATNSMNIPALVGK--GCLILSDELNHTSLVLGARLSGATIRIFKHNNTQSLEKLL 284
Query: 369 Q--------RSDPSVPKI-VAFETVHSMDGAVCPLEELCDVAHEFGAITFVDEVHAVGLY 419
+ R+ + KI + E V+SM+G++ L ++ + ++ A ++DE H++G
Sbjct: 285 RDAVIYGQPRTRRAWKKILILVEGVYSMEGSIVHLPQIIALKKKYKAYLYIDEAHSIGAV 344
Query: 420 GARGGGIGDRDGVMP-KMDIISGTLGKAFGCVGGYIASTSSLIDTVRSYAAGFIFTTSLP 478
G G G+ + G+ P ++D++ GT K+FG GGYIA L+D +R ++ ++ +S+
Sbjct: 345 GPTGRGVTEFFGLDPHEVDVLMGTFTKSFGASGGYIAGRKDLVDYLRVHSHSAVYASSMS 404
Query: 479 PMLLAGALESVRILKSAEGRV--LRRQHQ--RNVKLMRQMLMDAGLPVV-HCPSHIIPVR 533
P + + S++++ +G L+R Q +N + RQ L + G + + + ++P+
Sbjct: 405 PPIAEQIIRSLKLIMGLDGTTQGLQRVQQLAKNTRYFRQRLQEMGFIIYGNENASVVPLL 464
Query: 534 VADAAKNTEVCDELMSRHNIYVQAINYPTVPRGEELLRIAPTPHHTPQMMNYFLENL 590
+ K ++ + I V + +P P E R + HT +M++ LE L
Sbjct: 465 LYMPGKVAAFARHMLEK-KIGVVVVGFPATPLAEARARFCVSAAHTREMLDTVLEAL 520
>gi|5454084 serine palmitoyltransferase subunit 1 isoform a [Homo
sapiens]
Length = 473
Score = 127 bits (318), Expect = 4e-29
Identities = 78/271 (28%), Positives = 141/271 (52%), Gaps = 13/271 (4%)
Query: 238 SLITKKQVSVWCSNDYLGMSRHPRVCGAVMDTLKQHGAGAGGTRNISGTSKFHVDLEREL 297
+++ K+ + S ++LG+ +PRV A + +LK++G G G R GT H+DLE L
Sbjct: 93 TVVNGKECINFASFNFLGLLDNPRVKAAALASLKKYGVGTCGPRGFYGTFDVHLDLEDRL 152
Query: 298 ADLHGKDAALLFSSCFVANDSTLFTLAKMMPGCEIYSDSGNHASMIQGIRNSRVPKYIFR 357
A + A+++S F S + +K G ++ D ++ +G++ SR +F+
Sbjct: 153 AKFMKTEEAIIYSYGFATIASAIPAYSKR--GDIVFVDRAACFAIQKGLQASRSDIKLFK 210
Query: 358 HNDVSHLRELLQR---SDPSVP-------KIVAFETVHSMDGAVCPLEELCDVAHEFGAI 407
HND++ L LL+ D P + + E ++ G +CPL EL + +++ A
Sbjct: 211 HNDMADLERLLKEQEIEDQKNPRKARVTRRFIVVEGLYMNTGTICPLPELVKLKYKYKAR 270
Query: 408 TFVDEVHAVGLYGARGGGIGDRDGV-MPKMDIISGTLGKAFGCVGGYIASTSSLIDTVRS 466
F++E + G+ G G G+ + G+ + +D+IS + A +GG+ S +ID R
Sbjct: 271 IFLEESLSFGVLGEHGRGVTEHYGINIDDIDLISANMENALASIGGFCCGRSFVIDHQRL 330
Query: 467 YAAGFIFTTSLPPMLLAGALESVRILKSAEG 497
G+ F+ SLPP+L A A+E++ I++ G
Sbjct: 331 SGQGYCFSASLPPLLAAAAIEALNIMEENPG 361
>gi|30474871 serine palmitoyltransferase subunit 1 isoform b [Homo
sapiens]
Length = 143
Score = 34.3 bits (77), Expect = 0.36
Identities = 16/49 (32%), Positives = 29/49 (59%)
Query: 238 SLITKKQVSVWCSNDYLGMSRHPRVCGAVMDTLKQHGAGAGGTRNISGT 286
+++ K+ + S ++LG+ +PRV A + +LK++G G G R GT
Sbjct: 93 TVVNGKECINFASFNFLGLLDNPRVKAAALASLKKYGVGTCGPRGFYGT 141
>gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens]
Length = 904
Score = 34.3 bits (77), Expect = 0.36
Identities = 39/155 (25%), Positives = 54/155 (34%), Gaps = 19/155 (12%)
Query: 30 AQNCPKMMEVGAKPAPRALSTAAVHYQ-----QIKETPPASEKDKTAKAKVQQTPDGSQQ 84
A N P V A P P A S +VH + P + K +P G
Sbjct: 291 AGNSPARASVPAAPNPAATSATSVHVRSPARPSESRLAPTPTEGKVRPRVTNSSPMGWSS 350
Query: 85 SPDGTQLPSGHPL---------PATSQGTASKCPFLAAQMNQRGSSVFCKASLE---LQE 132
+ T + HP PAT QG + P +AA SS A+++
Sbjct: 351 AAPCTAAAASHPAVPPSAPDPRPATPQGGGA--PRVAAPQTTLSSSSTSAATVDPPAWTP 408
Query: 133 DVQEMNAVRKEVAETSAGPSVVSVKTDGGDPSGLL 167
R + +TSA P S+ G PS +L
Sbjct: 409 SASRTQQARNKFFQTSAVPPGTSLSGRGPTPSLVL 443
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 33.5 bits (75), Expect = 0.62
Identities = 27/84 (32%), Positives = 34/84 (40%), Gaps = 13/84 (15%)
Query: 36 MMEVGAKPAPR----------ALSTAAVHYQQIKETPPASEKDKTAKAKVQQTPDGSQQS 85
+ E+GA P P+ ALST V + TPP S + + Q P S Q
Sbjct: 4274 LQELGAGPRPQGPPRLPAPPGALSTGPV-LGPVHPTPPPSSPQEPKRPS--QLPSPSSQL 4330
Query: 86 PDGTQLPSGHPLPATSQGTASKCP 109
P QLP HP QG + P
Sbjct: 4331 PTEAQLPPTHPGTPKPQGPTLEPP 4354
>gi|42716289 erythrocyte membrane protein band 4.1 (elliptocytosis
1, RH-linked) isoform 1 [Homo sapiens]
Length = 775
Score = 32.7 bits (73), Expect = 1.1
Identities = 28/133 (21%), Positives = 50/133 (37%), Gaps = 4/133 (3%)
Query: 63 PASEKDKTAKAKVQQTPDGSQQSPDGTQLPSGHPLPATSQGTASKCPFLAAQMNQ----R 118
PA ++TA + ++ DG+ + P PA +QG ++ L A + +
Sbjct: 492 PAPHFERTASKRASRSLDGAAAVDSADRSPRPTSAPAITQGQVAEGGVLDASAKKTVVPK 551
Query: 119 GSSVFCKASLELQEDVQEMNAVRKEVAETSAGPSVVSVKTDGGDPSGLLKNFQDIMQKQR 178
KA ++ +++ E A S +K S L KNF + + + R
Sbjct: 552 AQKETVKAEVKKEDEPPEQAEPEPTEAWKDLDKSQEEIKKHHASISELKKNFMESVPEPR 611
Query: 179 PERVSHLLQDNLP 191
P L + P
Sbjct: 612 PSEWDKRLSTHSP 624
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 32.7 bits (73), Expect = 1.1
Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 4/80 (5%)
Query: 34 PKMMEVGAKPAPRALSTAAVHYQQIKETPPASEKDKTAKAKVQQ----TPDGSQQSPDGT 89
P KP P+ A QQ T P S++ +AK QQ P Q + +
Sbjct: 500 PSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVS 559
Query: 90 QLPSGHPLPATSQGTASKCP 109
Q SG PL + ++K P
Sbjct: 560 QTGSGKPLQPPTVSPSAKQP 579
Score = 30.0 bits (66), Expect = 6.8
Identities = 14/49 (28%), Positives = 24/49 (48%), Gaps = 5/49 (10%)
Query: 59 KETPPASEKDKTAKAKVQQTPDGSQQSPDGTQLPSGHPLPATSQGTASK 107
K+ P +K++ KA+ + +P PD +P G P P + TA +
Sbjct: 844 KQVDPVQKKEEPKKAQTKMSP-----KPDAKPMPKGSPTPPGPRPTAGQ 887
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 32.7 bits (73), Expect = 1.1
Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 4/80 (5%)
Query: 34 PKMMEVGAKPAPRALSTAAVHYQQIKETPPASEKDKTAKAKVQQ----TPDGSQQSPDGT 89
P KP P+ A QQ T P S++ +AK QQ P Q + +
Sbjct: 500 PSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVS 559
Query: 90 QLPSGHPLPATSQGTASKCP 109
Q SG PL + ++K P
Sbjct: 560 QTGSGKPLQPPTVSPSAKQP 579
Score = 30.0 bits (66), Expect = 6.8
Identities = 14/49 (28%), Positives = 24/49 (48%), Gaps = 5/49 (10%)
Query: 59 KETPPASEKDKTAKAKVQQTPDGSQQSPDGTQLPSGHPLPATSQGTASK 107
K+ P +K++ KA+ + +P PD +P G P P + TA +
Sbjct: 844 KQVDPVQKKEEPKKAQTKMSP-----KPDAKPMPKGSPTPPGPRPTAGQ 887
>gi|71725360 zinc finger protein 609 [Homo sapiens]
Length = 1411
Score = 31.6 bits (70), Expect = 2.3
Identities = 33/130 (25%), Positives = 54/130 (41%), Gaps = 8/130 (6%)
Query: 38 EVGAKPAPRALSTAAVHYQQIKETPPASEKDKTAKAKVQQTPDGSQQSPDGTQLPSGHPL 97
EVG PAP A++T + + + P K+ +K+K ++ + + GT L +
Sbjct: 56 EVGI-PAPNAVATLPDNIKFVTPVPGPQGKEGKSKSKRSKSGKDTSKPTPGTSLFTPSEG 114
Query: 98 PATSQ------GTASKCPFLAAQMNQRGSSVFCKASLELQEDVQEM-NAVRKEVAETSAG 150
A+ + G + L A + +GS KAS + +E N+ K E S G
Sbjct: 115 AASKKEVQGRSGDGANAGGLVAAIAPKGSEKAAKASRSVAGSKKEKENSSSKSKKERSEG 174
Query: 151 PSVVSVKTDG 160
S K G
Sbjct: 175 VGTCSEKDPG 184
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 31.2 bits (69), Expect = 3.1
Identities = 36/154 (23%), Positives = 66/154 (42%), Gaps = 22/154 (14%)
Query: 30 AQNCPKMMEVGAKPAPRALSTAAVHYQQIKETPPA----SEKDKTAKAKVQQTPDGSQQS 85
A+ P + A +P A A K +PPA +E+ +A + +P S+Q+
Sbjct: 687 AEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVSPPPSEQT 746
Query: 86 PDGTQLPSGHPLPATSQGTASKCPFLAAQMNQRGSSVFCKASLELQEDVQEMNAVRKEVA 145
P+ L + T + P +A + SV + + +E V ++N+V K+++
Sbjct: 747 PEDEAL-------VENVSTEFQSPQVAGIPAVKLGSVVLEGEAKFEE-VSKINSVLKDLS 798
Query: 146 ETSAGPSVVSVKTDGGDPSGLLKNFQDIMQKQRP 179
T+ DG P+ +++ I KQRP
Sbjct: 799 NTN----------DGQAPTLEIESVFHIELKQRP 822
>gi|13899233 tetratricopeptide repeat domain 25 [Homo sapiens]
Length = 672
Score = 31.2 bits (69), Expect = 3.1
Identities = 32/124 (25%), Positives = 55/124 (44%), Gaps = 6/124 (4%)
Query: 98 PATSQGTASKCPFLAAQMNQRGSSVFCKASLELQEDVQEMNAVRK--EVAETSAGPSVVS 155
PA +G K L + + VF +L+ D + ++K E S G S S
Sbjct: 78 PAFCKGILQKAETLYTMGDFEFALVFYHRGYKLRPDREFRVGIQKAQEAINNSVG-SPSS 136
Query: 156 VKTDG-GDPSGLLKNFQDIMQKQRPERVSHLLQDNL--PKSVSTFQYDRFFEKKIDEKKN 212
+K + GD S L K ++I +Q+P+ + HLL PK ++ + ++ + + E
Sbjct: 137 IKLENKGDLSFLSKQAENIKAQQKPQPMKHLLHPTKGEPKWKASLKSEKTVRQLLGELYV 196
Query: 213 DHTY 216
D Y
Sbjct: 197 DKEY 200
>gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo
sapiens]
Length = 834
Score = 30.8 bits (68), Expect = 4.0
Identities = 27/82 (32%), Positives = 35/82 (42%), Gaps = 15/82 (18%)
Query: 24 KSLLFYAQNCPKMMEVGAKPAPRALSTAAVHYQQIKETPPASEKDKTAKAKVQQTPDGSQ 83
+S LF QN + PA A S+A+ ++ I PP SEK+ TP G
Sbjct: 286 QSFLFGTQNTSP-----SSPAAPAASSASPMFKPIFTAPPKSEKE-------GPTPPGPS 333
Query: 84 QSPDGTQLPSGHPLPATSQGTA 105
S PS LP T+ TA
Sbjct: 334 VS---ATAPSSSSLPTTTSTTA 352
>gi|125625322 RALBP1 associated Eps domain containing 2 isoform 2
[Homo sapiens]
Length = 659
Score = 30.8 bits (68), Expect = 4.0
Identities = 22/112 (19%), Positives = 43/112 (38%)
Query: 30 AQNCPKMMEVGAKPAPRALSTAAVHYQQIKETPPASEKDKTAKAKVQQTPDGSQQSPDGT 89
A+ P++ ++ A + + V Y Q P + +A Q P + P
Sbjct: 532 AELLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASA 591
Query: 90 QLPSGHPLPATSQGTASKCPFLAAQMNQRGSSVFCKASLELQEDVQEMNAVR 141
HP K A + N+ ++V + + ELQ+ ++E++ R
Sbjct: 592 ATMKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQER 643
>gi|125625326 RALBP1 associated Eps domain containing 2 isoform 1
[Homo sapiens]
Length = 660
Score = 30.8 bits (68), Expect = 4.0
Identities = 22/112 (19%), Positives = 43/112 (38%)
Query: 30 AQNCPKMMEVGAKPAPRALSTAAVHYQQIKETPPASEKDKTAKAKVQQTPDGSQQSPDGT 89
A+ P++ ++ A + + V Y Q P + +A Q P + P
Sbjct: 533 AELLPQLSRAPSQAAESSPAKKDVLYSQPPSKPIRRKFRPENQATENQEPSTAASGPASA 592
Query: 90 QLPSGHPLPATSQGTASKCPFLAAQMNQRGSSVFCKASLELQEDVQEMNAVR 141
HP K A + N+ ++V + + ELQ+ ++E++ R
Sbjct: 593 ATMKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQER 644
>gi|50513245 chromatin assembly factor 1, subunit A (p150) [Homo
sapiens]
Length = 956
Score = 30.8 bits (68), Expect = 4.0
Identities = 40/155 (25%), Positives = 58/155 (37%), Gaps = 20/155 (12%)
Query: 6 RRCPFLSRVPQAFLQKAGKSLLFYAQNCPKMMEVGAKPAPRALSTAAVHYQQIKETPPAS 65
R CP L+ P+ +K S ++ G P AV QIK P
Sbjct: 205 RSCPELTSGPRMCPRKEQDSW----SEAGGILFKGKVPMVVLQDILAVRPPQIKSLPATP 260
Query: 66 E-KDKTAKAKVQQT--------PDGSQQSPDGTQLPSGHPLPATSQGTASKCPFLAAQMN 116
+ K+ T +++V ++ S SP T P G P P + S PF +
Sbjct: 261 QGKNMTPESEVLESFPEEDSVLSHSSLSSPSSTSSPEGPPAPPKQHSSTS--PFPTSTPL 318
Query: 117 QRGSSVFCKAS-----LELQEDVQEMNAVRKEVAE 146
+R + F K S L LQ D + + K AE
Sbjct: 319 RRITKKFVKGSTEKNKLRLQRDQERLGKQLKLRAE 353
>gi|29244924 chromodomain helicase DNA binding protein 6 [Homo
sapiens]
Length = 2715
Score = 30.8 bits (68), Expect = 4.0
Identities = 46/202 (22%), Positives = 72/202 (35%), Gaps = 14/202 (6%)
Query: 16 QAFLQKAGKSLLFYAQNCPKMMEVGAKPAPRALSTAAVHYQQIKETPPASEKDKTAKAKV 75
Q F + K L A P + A PAP A H + ++ E D+ K
Sbjct: 1906 QGFQDETKKGSLEVANQTPGLQR--AFPAPAACQC---HCKHMERWMHGLENDEFEIEKP 1960
Query: 76 QQTPDGSQQSPDGTQLPSGHPLPATSQGTASKCPFLAAQMNQ--RGSSVFCKASLELQE- 132
+ +S T G P SQ K L + G +VF LE E
Sbjct: 1961 KAYIPDLFKSKTNTIAMEGEPTAIPSQPFKVKHELLKEPWKESAEGQNVFPTYPLEGSEL 2020
Query: 133 DVQEMNAVRKEVAETSAG------PSVVSVKTDGGDPSGLLKNFQDIMQKQRPERVSHLL 186
++M+ K+ + P S + SG+ + D +Q+ R ++ LL
Sbjct: 2021 KSEDMDFENKDDYDRDGNCHSQDYPGKYSEEESKSSTSGITGDIGDELQEARAPTIAQLL 2080
Query: 187 QDNLPKSVSTFQYDRFFEKKID 208
Q+ S S + DR ++D
Sbjct: 2081 QEKTLYSFSEWPKDRVIINRLD 2102
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 30.8 bits (68), Expect = 4.0
Identities = 19/61 (31%), Positives = 26/61 (42%)
Query: 61 TPPASEKDKTAKAKVQQTPDGSQQSPDGTQLPSGHPLPATSQGTASKCPFLAAQMNQRGS 120
TPP+ + T A +P G P T PS LP +G A+ P A ++ S
Sbjct: 857 TPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSS 916
Query: 121 S 121
S
Sbjct: 917 S 917
Score = 30.4 bits (67), Expect = 5.2
Identities = 24/73 (32%), Positives = 31/73 (42%), Gaps = 7/73 (9%)
Query: 41 AKPAPRALSTA-AVHYQQIKETPPASEKDKTAKAKVQQTPDGSQQSPDGTQLPSGHP--- 96
A P+P+ T AV K +P A+ K A TP + SP T LP G P
Sbjct: 1001 ATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTP 1060
Query: 97 ---LPATSQGTAS 106
LP+ G A+
Sbjct: 1061 AATLPSPKGGPAT 1073
>gi|21536357 TBP-associated factor 6 isoform delta [Homo sapiens]
Length = 667
Score = 30.4 bits (67), Expect = 5.2
Identities = 36/161 (22%), Positives = 61/161 (37%), Gaps = 14/161 (8%)
Query: 14 VPQAFLQKAGKSLLFYAQNCPKMMEVGAKPAPRALSTAAV--HYQQIKETPPASEKDKTA 71
+P F G+ L FY + + ++ P PR + H+ I+ PA ++
Sbjct: 82 IPFRFASGGGRELYFYEEKEVDLSDIINTPLPRVPLDVCLKAHWLSIEGCQPAIPENPPP 141
Query: 72 KAKVQQTPDGSQ--------QSPDGTQLPSGH-PLPATSQGTASKCPFL--AAQMNQRGS 120
K QQ + ++ Q DG G A +G K P L A + +
Sbjct: 142 APKEQQKAEATEPLKSAKPGQEEDGPLKGKGQGATTADGKGKEKKAPPLLEGAPLRLKPR 201
Query: 121 SVFCKASLELQEDVQEMNAVRKEVAETSAGPSVVSVKTDGG 161
S+ + S+E Q +E+ E ++ S+ TD G
Sbjct: 202 SIH-ELSVEQQLYYKEITEACVGSCEAKRAEALQSIATDPG 241
>gi|21536355 TBP-associated factor 6 isoform gamma [Homo sapiens]
Length = 667
Score = 30.4 bits (67), Expect = 5.2
Identities = 36/161 (22%), Positives = 61/161 (37%), Gaps = 14/161 (8%)
Query: 14 VPQAFLQKAGKSLLFYAQNCPKMMEVGAKPAPRALSTAAV--HYQQIKETPPASEKDKTA 71
+P F G+ L FY + + ++ P PR + H+ I+ PA ++
Sbjct: 92 IPFRFASGGGRELYFYEEKEVDLSDIINTPLPRVPLDVCLKAHWLSIEGCQPAIPENPPP 151
Query: 72 KAKVQQTPDGSQ--------QSPDGTQLPSGH-PLPATSQGTASKCPFL--AAQMNQRGS 120
K QQ + ++ Q DG G A +G K P L A + +
Sbjct: 152 APKEQQKAEATEPLKSAKPGQEEDGPLKGKGQGATTADGKGKEKKAPPLLEGAPLRLKPR 211
Query: 121 SVFCKASLELQEDVQEMNAVRKEVAETSAGPSVVSVKTDGG 161
S+ + S+E Q +E+ E ++ S+ TD G
Sbjct: 212 SIH-ELSVEQQLYYKEITEACVGSCEAKRAEALQSIATDPG 251
>gi|5032147 TBP-associated factor 6 isoform alpha [Homo sapiens]
Length = 677
Score = 30.4 bits (67), Expect = 5.2
Identities = 36/161 (22%), Positives = 61/161 (37%), Gaps = 14/161 (8%)
Query: 14 VPQAFLQKAGKSLLFYAQNCPKMMEVGAKPAPRALSTAAV--HYQQIKETPPASEKDKTA 71
+P F G+ L FY + + ++ P PR + H+ I+ PA ++
Sbjct: 92 IPFRFASGGGRELYFYEEKEVDLSDIINTPLPRVPLDVCLKAHWLSIEGCQPAIPENPPP 151
Query: 72 KAKVQQTPDGSQ--------QSPDGTQLPSGH-PLPATSQGTASKCPFL--AAQMNQRGS 120
K QQ + ++ Q DG G A +G K P L A + +
Sbjct: 152 APKEQQKAEATEPLKSAKPGQEEDGPLKGKGQGATTADGKGKEKKAPPLLEGAPLRLKPR 211
Query: 121 SVFCKASLELQEDVQEMNAVRKEVAETSAGPSVVSVKTDGG 161
S+ + S+E Q +E+ E ++ S+ TD G
Sbjct: 212 SIH-ELSVEQQLYYKEITEACVGSCEAKRAEALQSIATDPG 251
>gi|21536359 TBP-associated factor 6 isoform alpha [Homo sapiens]
Length = 677
Score = 30.4 bits (67), Expect = 5.2
Identities = 36/161 (22%), Positives = 61/161 (37%), Gaps = 14/161 (8%)
Query: 14 VPQAFLQKAGKSLLFYAQNCPKMMEVGAKPAPRALSTAAV--HYQQIKETPPASEKDKTA 71
+P F G+ L FY + + ++ P PR + H+ I+ PA ++
Sbjct: 92 IPFRFASGGGRELYFYEEKEVDLSDIINTPLPRVPLDVCLKAHWLSIEGCQPAIPENPPP 151
Query: 72 KAKVQQTPDGSQ--------QSPDGTQLPSGH-PLPATSQGTASKCPFL--AAQMNQRGS 120
K QQ + ++ Q DG G A +G K P L A + +
Sbjct: 152 APKEQQKAEATEPLKSAKPGQEEDGPLKGKGQGATTADGKGKEKKAPPLLEGAPLRLKPR 211
Query: 121 SVFCKASLELQEDVQEMNAVRKEVAETSAGPSVVSVKTDGG 161
S+ + S+E Q +E+ E ++ S+ TD G
Sbjct: 212 SIH-ELSVEQQLYYKEITEACVGSCEAKRAEALQSIATDPG 251
>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
sapiens]
Length = 691
Score = 30.4 bits (67), Expect = 5.2
Identities = 20/82 (24%), Positives = 32/82 (39%), Gaps = 3/82 (3%)
Query: 31 QNCPKMMEVGAKPAPRALSTAAVHYQQI---KETPPASEKDKTAKAKVQQTPDGSQQSPD 87
Q P +PAP+A S + Q ++ PPAS++ +++QQ P Q P
Sbjct: 195 QQPPPSTNQHPQPAPQAPSQSQQQPLQPTPPQQPPPASQQPPAPTSQLQQAPQPQQHQPH 254
Query: 88 GTQLPSGHPLPATSQGTASKCP 109
P P + + P
Sbjct: 255 SHSQNQNQPSPTQQSSSPPQKP 276
>gi|56549694 enabled homolog isoform a [Homo sapiens]
Length = 591
Score = 30.0 bits (66), Expect = 6.8
Identities = 27/141 (19%), Positives = 56/141 (39%), Gaps = 8/141 (5%)
Query: 37 MEVGAKPAPRALSTAAVHYQQIKETPPASEKDKTAKAKVQQTPDGSQQSPDGTQLPSGHP 96
+ +G +S ++I E E ++ P S+ S T P+ P
Sbjct: 437 LPLGGSGLMEEMSALLARRRRIAEKGSTIETEQKEDKGEDSEPVTSKASSTSTPEPTRKP 496
Query: 97 LPATSQGTASKCPFLAAQMNQRGSSVFCKASLELQEDVQEMNAVRKEVAETSAGPSVVSV 156
T+ SK P ++ + + R + + D + +++ + + + PS V
Sbjct: 497 WERTNTMNGSKSPVISRRDSPRKNQIVF--------DNRSYDSLHRPKSTPLSQPSANGV 548
Query: 157 KTDGGDPSGLLKNFQDIMQKQ 177
+T+G D L ++ D M+K+
Sbjct: 549 QTEGLDYDRLKQDILDEMRKE 569
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.133 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,454,242
Number of Sequences: 37866
Number of extensions: 1125403
Number of successful extensions: 3859
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 19
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 3795
Number of HSP's gapped (non-prelim): 87
length of query: 640
length of database: 18,247,518
effective HSP length: 109
effective length of query: 531
effective length of database: 14,120,124
effective search space: 7497785844
effective search space used: 7497785844
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.