Guide to the Human Genome
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Name: ALAS1 Sequence: fasta or formatted (640aa) NCBI GI: 4502025
Description:

5-aminolevulinate synthase 1

Referenced in:

Heme

Other entries for this name:
alt mRNA [640aa] 5-aminolevulinate synthase 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.1         52           2
 C cysteine            2.3         15           1
 D aspartate           5.2         33           2
 E glutamate           5.2         33           2
 F phenylalanine       4.1         26           2
 G glycine             6.7         43           3
 H histidine           3.6         23           2
 I isoleucine          3.8         24           2
 K lysine              5.9         38           2
 L leucine             8.3         53           2
 M methionine          3.6         23           2
 N asparagine          3.1         20           1
 P proline             5.8         37           2
 Q glutamine           4.8         31           2
 R arginine            5.8         37           2
 S serine              8.6         55           2
 T threonine           4.7         30           2
 V valine              7.8         50           2
 W tryptophan          0.3          2           1
 Y tyrosine            2.3         15           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   5-aminolevulinate synthase 1 
ALAS1                 1.000   5-aminolevulinate synthase 1 
ALAS2                 0.545   5-aminolevulinate synthase 2 isoform a precursor [Ho...
ALAS2                 0.524   5-aminolevulinate synthase 2 isoform c precursor [Ho...
ALAS2                 0.524   5-aminolevulinate synthase 2 isoform b precursor [Ho...
GCAT                  0.142   glycine C-acetyltransferase precursor 
SPTLC2                0.104   serine palmitoyltransferase, long chain base subunit ...
SPTLC3                0.094   serine palmitoyltransferase, long chain base subuni...
SPTLC1                0.081   serine palmitoyltransferase subunit 1 isoform a [Homo...
SPTLC1                0.007   serine palmitoyltransferase subunit 1 isoform b [Hom...
MICALL2               0.007   MICAL-like 2 isoform 1 
MLL2                  0.006   myeloid/lymphoid or mixed-lineage leukemia 2 
EPB41                 0.006   erythrocyte membrane protein band 4.1 (elliptocytosi...
PCLO                  0.006   piccolo isoform 2 
PCLO                  0.006   piccolo isoform 1 
ZNF609                0.006   zinc finger protein 609 
FSCB                  0.005   fibrous sheath CABYR binding protein 
TTC25                 0.005   tetratricopeptide repeat domain 25 
LOC100288540          0.005   PREDICTED: hypothetical protein XP_002342775 
REPS2                 0.005   RALBP1 associated Eps domain containing 2 isoform 2...
REPS2                 0.005   RALBP1 associated Eps domain containing 2 isoform 1...
CHAF1A                0.005   chromatin assembly factor 1, subunit A (p150) 
CHD6                  0.005   chromodomain helicase DNA binding protein 6 
NACA                  0.005   nascent polypeptide-associated complex alpha subuni...
TAF6                  0.004   TBP-associated factor 6 isoform delta 
TAF6                  0.004   TBP-associated factor 6 isoform gamma 
TAF6                  0.004   TBP-associated factor 6 isoform alpha 
TAF6                  0.004   TBP-associated factor 6 isoform alpha 
POU6F2                0.004   POU domain, class 6, transcription factor 2 
ENAH                  0.004   enabled homolog isoform a 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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