Guide to the Human Genome
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Search of human proteins with 39930523

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|39930523 hypothetical protein LOC144097 [Homo sapiens]
         (381 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|39930523 hypothetical protein LOC144097 [Homo sapiens]             784   0.0  
gi|222144283 hypothetical protein LOC65998 [Homo sapiens]              66   5e-11
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         57   4e-08
gi|33286446 opioid growth factor receptor [Homo sapiens]               49   8e-06
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    48   1e-05
gi|149158690 HLA-B associated transcript-2 [Homo sapiens]              48   2e-05
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    47   3e-05
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    47   3e-05
gi|150170670 piccolo isoform 2 [Homo sapiens]                          46   5e-05
gi|150378539 piccolo isoform 1 [Homo sapiens]                          46   5e-05
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    46   6e-05
gi|54860079 nadrin isoform 1 [Homo sapiens]                            44   2e-04
gi|54860105 nadrin isoform 2 [Homo sapiens]                            44   2e-04
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]       44   2e-04
gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo sap...    44   2e-04
gi|118498339 EMI domain containing 2 [Homo sapiens]                    44   3e-04
gi|239753975 PREDICTED: hypothetical protein [Homo sapiens]            43   5e-04
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     42   7e-04
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ...    42   0.001
gi|41281612 zinc finger protein 828 [Homo sapiens]                     42   0.001
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    42   0.001
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    42   0.001
gi|12669915 E2F transcription factor 4 [Homo sapiens]                  42   0.001
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        42   0.001
gi|148806908 fibronectin type III domain containing 1 [Homo sapi...    40   0.005
gi|157785645 SPEG complex locus [Homo sapiens]                         40   0.005
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  39   0.006
gi|5031855 lymphocyte cytosolic protein 2 [Homo sapiens]               39   0.006
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   39   0.006
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   39   0.006

>gi|39930523 hypothetical protein LOC144097 [Homo sapiens]
          Length = 381

 Score =  784 bits (2025), Expect = 0.0
 Identities = 381/381 (100%), Positives = 381/381 (100%)

Query: 1   MALKAEGAALDCFEVTLKCEEGEDEEEAMVVAVIPRPEPMLRVTQQEKTPPPRPSPLEAG 60
           MALKAEGAALDCFEVTLKCEEGEDEEEAMVVAVIPRPEPMLRVTQQEKTPPPRPSPLEAG
Sbjct: 1   MALKAEGAALDCFEVTLKCEEGEDEEEAMVVAVIPRPEPMLRVTQQEKTPPPRPSPLEAG 60

Query: 61  SDGCEEPKQQVSWEQEFLVGSSPGGSGRALCMVCGAEIRAPSADTARSHILEQHPHTLDL 120
           SDGCEEPKQQVSWEQEFLVGSSPGGSGRALCMVCGAEIRAPSADTARSHILEQHPHTLDL
Sbjct: 61  SDGCEEPKQQVSWEQEFLVGSSPGGSGRALCMVCGAEIRAPSADTARSHILEQHPHTLDL 120

Query: 121 SPSEKSNILEAWSEGVALLQDVRAEQPSPPNSDSGQDAHPDPDANPDAARMPAEIVVLLD 180
           SPSEKSNILEAWSEGVALLQDVRAEQPSPPNSDSGQDAHPDPDANPDAARMPAEIVVLLD
Sbjct: 121 SPSEKSNILEAWSEGVALLQDVRAEQPSPPNSDSGQDAHPDPDANPDAARMPAEIVVLLD 180

Query: 181 SEDNPSLPKRSRPRGLRPLELPAVPATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNL 240
           SEDNPSLPKRSRPRGLRPLELPAVPATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNL
Sbjct: 181 SEDNPSLPKRSRPRGLRPLELPAVPATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNL 240

Query: 241 DPDPEPPSPDSPTETFAAPAEVRHFTDGSFPAGFVLQLFSHTQLRGPDSKDSPKDREVAE 300
           DPDPEPPSPDSPTETFAAPAEVRHFTDGSFPAGFVLQLFSHTQLRGPDSKDSPKDREVAE
Sbjct: 241 DPDPEPPSPDSPTETFAAPAEVRHFTDGSFPAGFVLQLFSHTQLRGPDSKDSPKDREVAE 300

Query: 301 GGLPRAESPSPAPPPGLRGTLDLQVIRVRMEEPPAVSLLQDWSRHPQGTKRVGAGDTSDW 360
           GGLPRAESPSPAPPPGLRGTLDLQVIRVRMEEPPAVSLLQDWSRHPQGTKRVGAGDTSDW
Sbjct: 301 GGLPRAESPSPAPPPGLRGTLDLQVIRVRMEEPPAVSLLQDWSRHPQGTKRVGAGDTSDW 360

Query: 361 PTVLSESSTTVAGKPEKGNGV 381
           PTVLSESSTTVAGKPEKGNGV
Sbjct: 361 PTVLSESSTTVAGKPEKGNGV 381


>gi|222144283 hypothetical protein LOC65998 [Homo sapiens]
          Length = 678

 Score = 66.2 bits (160), Expect = 5e-11
 Identities = 48/142 (33%), Positives = 64/142 (45%), Gaps = 20/142 (14%)

Query: 20  EEGEDEEEAMVVAVIPRPEPMLRVTQQEKTPPPRPSPLEAGSDGCEEPKQQVSWEQEFLV 79
           EE EDEE+      +  P P          PPP P P     +  +    Q  W  E+L+
Sbjct: 544 EEEEDEEDGQEPGGLALPPP----------PPPPPPPPPRSRE--QRRNYQPRWRGEYLM 591

Query: 80  GSSPGGSGRAL-CMVCGAEIRAPSADTARSHILEQHPHTLDLSPSEKSNILEAWSEGVAL 138
                GS R L CMVCG  +      T + HIL+ HP ++D +P E+  ILEA+ E  A 
Sbjct: 592 DYD--GSRRGLVCMVCGGALATLKVSTIKRHILQVHPFSMDFTPEERQTILEAYEE--AA 647

Query: 139 LQDVRAE---QPSPPNSDSGQD 157
           L+    E    P+P   D G D
Sbjct: 648 LRCYGHEGFGPPAPAPRDGGAD 669



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 34/114 (29%), Positives = 51/114 (44%), Gaps = 19/114 (16%)

Query: 76  EFLVGSSPGGSGRALCMVCGAEIRAPSADTARSHILEQHPHTLDLSPSEKSNILEAWSEG 135
           E L+   P G+ R +CM CG  + +   D  R+H+LE HP +L LS  ++S +L+AW   
Sbjct: 271 ECLMDYDPRGN-RLVCMACGRALPSLHLDDIRAHVLEVHPGSLGLSGPQRSALLQAWGGQ 329

Query: 136 VALLQDVRAEQP-----------------SPPNSDSGQDAHPDPDANPDAARMP 172
              L ++    P                 S   + S QD  P PD   +A  +P
Sbjct: 330 PEALSELTQSPPGDDLAPQDLTGKSRDSASAAGAPSSQDLSP-PDVKEEAGWVP 382



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 23/66 (34%), Positives = 36/66 (54%), Gaps = 1/66 (1%)

Query: 73  WEQEFLVGSSPGGSGRALCMVCGAEIRAPSADTARSHILEQHPHTLDLSPSEKSNILEAW 132
           W  E+L+  +P   G  +CMVCG+ +      T + HI ++HP++L  SP EK  I  +W
Sbjct: 109 WRLEYLMDFNPARHGM-VCMVCGSSLATLKLSTIKRHIRQKHPYSLHWSPREKEVISNSW 167

Query: 133 SEGVAL 138
              + L
Sbjct: 168 DAHLGL 173



 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 60/224 (26%), Positives = 84/224 (37%), Gaps = 21/224 (9%)

Query: 25  EEEAMVVAVIPRP---EPMLRVTQQEKTPPPRPSPLEAGSDGCEEPKQQVSWEQEFLVGS 81
           +EEA  V   P P   E  L   + E+   P  SP   G      P+++  W  E+L+  
Sbjct: 375 KEEAGWVPERPGPAEEEEELEEGEGERAGVPGRSP--RGRAHRRHPQER--WRLEYLM-E 429

Query: 82  SPGGSGRALCMVCGAEIRAPSADTARSHILEQHPHTLDLSPSEKSNILEAWSEGVALLQD 141
             GG    +C VCG  + +    T   HI  +HP +  L    ++ I   WSE  A L  
Sbjct: 430 LDGGRRGLVCGVCGGALASLKMSTIERHIRRRHPGSTRLGGPVQALIAREWSEKAAHLLA 489

Query: 142 VRAEQPSPPNS--DSGQDAHPDPDANPDAARMPAEIVVLLDSEDNPSLPKRSRPRGLRPL 199
           +   +P  P      G  A  D +   D    P E     + E+   +P         PL
Sbjct: 490 LGPPRPESPQGPIPPGTAAASD-EGGGDEEEEPEE-----EEEEWGDVPLSPG----APL 539

Query: 200 ELPA-VPATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDP 242
           E PA     E   ++P G     PP   P    R R   +N  P
Sbjct: 540 ERPAEEEEDEEDGQEPGGLALPPPPPPPPPPPPRSREQRRNYQP 583


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 84/351 (23%), Positives = 118/351 (33%), Gaps = 55/351 (15%)

Query: 44  TQQEKTPPPRPSPLEAGSDGCEEPK-----------QQVSWEQEFLVGSSPGGSGRALCM 92
           T++ ++P P P P +      EE K           Q+  + ++    SS  GS  +   
Sbjct: 445 TEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSS--- 501

Query: 93  VCGAEIRAPSADTARSHILE-------QHPHTLDLSPSEKSNILEAWSEGVALLQDVRAE 145
              +E   P     RSH+         +H  +   SPS +    E    G       R  
Sbjct: 502 ---SEDERPK----RSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGR------RRR 548

Query: 146 QPSPPNSDSGQDAHPDPDANPDAARMPAEIVVLLDSEDNPSLPKRSRPRGLRPLELPAVP 205
            PSPP +   +   P P   P   R P            PS P R R    R    P   
Sbjct: 549 SPSPPPTRRRRSPSPAPP--PRRRRTPTPP----PRRRTPSPPPRRRSPSPRRYSPPIQR 602

Query: 206 ATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPSPDSPTETFAAPAEVRHF 265
              P    P  +R   PP     R     P  + +   P P    SP     +P+     
Sbjct: 603 RYSPS--PPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKH 660

Query: 266 TDGSFPAGFVLQLFSHTQLRGPDSKDSPKDREVAEGGLPRAESPSPAPPPGLRGTLDLQV 325
             GS P+    +  S      P+ + SP  R       PRA   S +PPP  RG      
Sbjct: 661 RKGSSPSRSTREARSPQ----PNKRHSPSPR-------PRAPQTSSSPPPVRRGASSSP- 708

Query: 326 IRVRMEEPPAVSLLQDWSRHPQGTKRVGAGDTSDWPTVLSESSTTVAGKPE 376
            + R    P+   ++  SR P+  K   A   S        SS +V+G PE
Sbjct: 709 -QRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPE 758



 Score = 31.6 bits (70), Expect = 1.2
 Identities = 67/302 (22%), Positives = 103/302 (34%), Gaps = 60/302 (19%)

Query: 36  RPEPMLRVTQQEKTPPPR--PSPLEAGSDGCEEPKQQVSWEQEFLVGSSPGGSGRALCMV 93
           RP P  R + + +TPP R  P P    S     P ++       L GSS           
Sbjct: 314 RPSPRRRPSPRRRTPPRRMPPPPRHRRS---RSPVRRRRRSSASLSGSSS---------- 360

Query: 94  CGAEIRAPSADTARSHILEQHPHTLDLSPSEKSNILEAWSEGVALLQDVRAEQPSPPNSD 153
                   S+ ++RS    + P     SP  K+  L   +         R  +PSPP + 
Sbjct: 361 --------SSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPR-----RRHRPSPPATP 407

Query: 154 SGQDAH-PDPDANPDAARMPAEIVVLLDSEDNPSLPKRSRPRGLRPLELPAVPATEPG-- 210
             +  H P P  +    +    +          +  K ++ +G    E P+ PA +P   
Sbjct: 408 PPKTRHSPTPQQSNRTRKSRVSV------SPGRTSGKVTKHKGTEKRESPS-PAPKPRKV 460

Query: 211 ----NKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPSPDS-PTETFAAPAEV--- 262
               +++ +G +       +  R+ R +    + D      S D  P  +     EV   
Sbjct: 461 ELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRR 520

Query: 263 -RHFTDGSFPAGFVLQLFSHTQLRGPDSKDSPKDREVAEGGLP---RAESPSPAPPPGLR 318
            RH    S          +    R    + SP+ R       P   R  SPSPAPPP  R
Sbjct: 521 RRHSPSRS----------ASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRR 570

Query: 319 GT 320
            T
Sbjct: 571 RT 572


>gi|33286446 opioid growth factor receptor [Homo sapiens]
          Length = 677

 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 72/306 (23%), Positives = 106/306 (34%), Gaps = 52/306 (16%)

Query: 36  RPEPM---------LRVTQQEKTPPPRPSPLEAGS--------DGCEEPKQQVSWEQEFL 78
           RPEP+         L ++++E+ PP  P P  A          +GC   +  +    + +
Sbjct: 373 RPEPLSPKESKKRKLELSRREQ-PPTEPGPQSASEVEKIALNLEGCALSQGSLRTGTQEV 431

Query: 79  VGSSPGGSGRALCMVCGAEIRAPSADTARSHILEQHPHTLDLSPSEKSNILEAWSEGVAL 138
            G  PG + +      GA +    AD  R          +D    + + +    ++ +AL
Sbjct: 432 GGQDPGEAVQPCRQPLGARV----ADKVRKR------RKVDEGAGDSAAVASGGAQTLAL 481

Query: 139 LQDVRAEQPSPPNSDSGQDAHPDPDANPDAARMPAEIVVLLDSEDNPSLPKRSRPRGLRP 198
                A  P+P        +    + + +    P E      SE  P  P  + P G  P
Sbjct: 482 -----AGSPAPSGHPKAGHSENGVEEDTEGRTGPKEGTPGSPSE-TPG-PSPAGPAGDEP 534

Query: 199 LELPA-VPATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPSPDSPTETFA 257
            E P+  P   P    P G    E P E P  +  G    +  +   E P P     T  
Sbjct: 535 AESPSETPGPRPAG--PAGDEPAESPSETPGPRPAGPAGDEPAESPSETPGPSPAGPTRD 592

Query: 258 APAEVRHFTDGSFPAGFVLQLFSHTQLRGPDSKDSPKD----REVAEGGLPRAESPSPAP 313
            PAE    T G  PAG            G +  +SP +    R     G   AESPS  P
Sbjct: 593 EPAESPSETPGPRPAG----------PAGDEPAESPSETPGPRPAGPAGDEPAESPSETP 642

Query: 314 PPGLRG 319
            P   G
Sbjct: 643 GPSPAG 648


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 56/198 (28%), Positives = 70/198 (35%), Gaps = 40/198 (20%)

Query: 147 PSPPNS-DSGQDAHPDPDANPDAARMPAEIVV-----------LLDSEDNPSLPKRSRPR 194
           PSPP S      A P P A P  A  P + +               S   P  P  + P 
Sbjct: 770 PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 829

Query: 195 GLRP------LELPAVPATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPS 248
              P      L++P  P   P  + PR      PP   P     G  +T  L P P PP 
Sbjct: 830 QAPPVLAAPLLQVPPSPPASPTLQAPR-----RPPTPGPDTSVSGPRLTLALAPGPPPPP 884

Query: 249 PDSPTETFAAPAEVRHFTDGSFPAGFVLQLFSHTQLRGPDS-------KDSPKDREVAEG 301
             SP+ T + P    H +  +          +  +LRG DS          P D E+A  
Sbjct: 885 SRSPSSTLSGPDLAGHSSSAT---------STPEELRGYDSGPEGGAAASPPPDAELA-A 934

Query: 302 GLPRAESPSPAPPPGLRG 319
             P A S  PAPP   RG
Sbjct: 935 CHPAAWSRGPAPPLAFRG 952



 Score = 33.1 bits (74), Expect = 0.43
 Identities = 46/206 (22%), Positives = 70/206 (33%), Gaps = 20/206 (9%)

Query: 148 SPPNSDSGQDAHPDPDANPDAARMPAEIVVLLDSEDNPSLPKRSRPR-GLRPLELPAVPA 206
           +PP       A P P A P  A  P + +         + P ++ P   L PL+ P  P 
Sbjct: 578 TPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPP 637

Query: 207 TEP-----GNKKPRG---------QRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPSPDSP 252
             P         P+          Q    PP   PV+     P +  + P   PPS  +P
Sbjct: 638 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS-QAP 696

Query: 253 TETFAAPAEVRHFTDGSFPAGFVLQLFSHTQLRGPDSKDSPKDREVAEGGLPRAESPSPA 312
               A P +V      S PA   +   +    + P    +P  +           SPS  
Sbjct: 697 PSLAAPPLQV----PPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSAT 752

Query: 313 PPPGLRGTLDLQVIRVRMEEPPAVSL 338
           PPP +   L    ++V    P ++ +
Sbjct: 753 PPPRVPPLLAAPPLQVPPSPPASLPM 778



 Score = 29.3 bits (64), Expect = 6.2
 Identities = 25/96 (26%), Positives = 35/96 (36%), Gaps = 22/96 (22%)

Query: 185 PSLPKRSRPRGLRPLELP--------AVPATEPGNKKPRGQRWKEPPGEE----PVRKKR 232
           P+ P + +P+GL+ L  P        A PA  P +  P       P G +    P     
Sbjct: 266 PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT--PSPSGTKARPVPPPDNA 323

Query: 233 GRPMTKNLDPDP--------EPPSPDSPTETFAAPA 260
             P+   L P P         PPSP +P      P+
Sbjct: 324 ATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPS 359


>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
          Length = 2157

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 58/231 (25%), Positives = 84/231 (36%), Gaps = 44/231 (19%)

Query: 36   RPEPMLRVTQQEKTPPPRPSPLEAGSDGCEEPKQQVSWEQEFLVGSSPGGSGRALCMVCG 95
            RP     + Q+E  PPP  S                       +GS P G G        
Sbjct: 1563 RPPRKPELLQEESLPPPHSSGF---------------------LGSKPEGPGPQ------ 1595

Query: 96   AEIRAPSADTARSHILEQHPHTLDLSPSEKSNILEAWSEGVALLQDVRAEQPSPPNSDSG 155
            AE R    +    HI  +  HT     S + + +E W E ++  +DV   + S   SDSG
Sbjct: 1596 AESRDTGTEALTPHIWNRL-HTATSRKSYRPSSMEPWMEPLSPFEDVAGTEMS--QSDSG 1652

Query: 156  QDAHPDP--DANPDAARMPAEIVVLLDSEDNPSLPKRSRPRGLRPLELP--------AVP 205
             D   D    + P + R   +  +   +E  P  P  S P    P E P          P
Sbjct: 1653 VDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGSEPPRRPPP 1712

Query: 206  ATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPS--PDSPTE 254
            A   G++K   +    PPG  P+  +R +   +  +P P  PS  P  P +
Sbjct: 1713 APHDGDRKELPREQPLPPG--PIGTERSQRTDRGTEPGPIRPSHRPGPPVQ 1761



 Score = 36.2 bits (82), Expect = 0.050
 Identities = 44/156 (28%), Positives = 61/156 (39%), Gaps = 24/156 (15%)

Query: 100 APSADTARSHILEQHPHTLDLSPSEKSNILEAWSEGVALLQDVRAEQPSPPNSDSGQDAH 159
           AP    +R  + E  P  L   P          S+ VA +Q    ++  PP  ++ Q   
Sbjct: 846 APGPPISRFPLEEPGPRPLPWPPG---------SDEVAKIQTPPPKK-EPPKEETAQLT- 894

Query: 160 PDPDANPDAARMPAEIVVLLDSEDNPSLPKR-SRPR---GLRP-LELPAVPATEPGNKKP 214
                 P+A R PA  V        P  P+R SR     G RP      +P  EPG    
Sbjct: 895 -----GPEAGRKPARGVG--SGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPR 947

Query: 215 RGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPSPD 250
           R    K+PP    V +   +P+ +  D  P+PP PD
Sbjct: 948 RAGPIKKPPPPTKVEELPPKPLEQG-DETPKPPKPD 982



 Score = 32.7 bits (73), Expect = 0.56
 Identities = 28/89 (31%), Positives = 37/89 (41%), Gaps = 8/89 (8%)

Query: 227  PVRKKRGRPMTKNLDPDPEPPSPDSPTETFAAPAEVRHFTDGSFPAGFVLQLFSHTQLRG 286
            P  K R RP  +     P PP P S +  F     +      S PAG    L   +  +G
Sbjct: 1434 PSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIH-----SNPAGIQQALAQLSSRQG 1488

Query: 287  PDSKDSPKDREVAEGGLPRA-ESPSPAPP 314
              S  +P      + GLP+A + PSP PP
Sbjct: 1489 --SVTAPGGHPRHKPGLPQAPQGPSPRPP 1515



 Score = 32.3 bits (72), Expect = 0.73
 Identities = 43/176 (24%), Positives = 62/176 (35%), Gaps = 21/176 (11%)

Query: 189 KRSRPRGLRPLELPAVPATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPS 248
           KR +     P   P+ PA  P   K        PP   P       P T+  +P   PP+
Sbjct: 502 KRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPT------PETEPEEPAQAPPA 555

Query: 249 PDSPTETFAAP-------AEVRHFTDGSFPAGFV-LQLFSH------TQLRGPDSKDSPK 294
             +PT   AA              + GSF A  V  QL S        ++  P +   PK
Sbjct: 556 QSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPK 615

Query: 295 DREVAEGGLPRAESPSPA-PPPGLRGTLDLQVIRVRMEEPPAVSLLQDWSRHPQGT 349
                +G  P  + PS     P  + +L  +  R + E+         W +H QG+
Sbjct: 616 VEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGS 671


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 54/199 (27%), Positives = 70/199 (35%), Gaps = 39/199 (19%)

Query: 145 EQPSPPNSDSGQDAHPDPDANPDAARMPAEIVV-----------LLDSEDNPSLPKRSRP 193
           + P P  +   Q A P P A P  A  P + +               S   P  P  + P
Sbjct: 500 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 559

Query: 194 RGLRP------LELPAVPATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPP 247
               P      L++P  P   P  + PR      PP   P     G  +T  L P P PP
Sbjct: 560 PQAPPVLAAPLLQVPPSPPASPTLQAPR-----RPPTPGPDTSVSGPRLTLALAPGPPPP 614

Query: 248 SPDSPTETFAAPAEVRHFTDGSFPAGFVLQLFSHTQLRGPDS-------KDSPKDREVAE 300
              SP+ T + P    H +  +          +  +LRG DS          P D E+A 
Sbjct: 615 PSRSPSSTLSGPDLAGHSSSAT---------STPEELRGYDSGPEGGAAASPPPDAELA- 664

Query: 301 GGLPRAESPSPAPPPGLRG 319
              P A S  PAPP   RG
Sbjct: 665 ACHPAAWSRGPAPPLAFRG 683



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 71/308 (23%), Positives = 100/308 (32%), Gaps = 60/308 (19%)

Query: 35  PRPEPMLRVTQQEKTPP-----PRPSPLEAGSDGCEEPKQQVSWEQEFLVGSSPGGSGRA 89
           P+P+ +  +   + TPP     P   PL +       P   +  +    + ++P  S   
Sbjct: 272 PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLT 331

Query: 90  LCMVCGAEIRAPSADTARSHILEQHPHTLDLSPSEKSNILEAWSEGVALLQDVRAEQPSP 149
             +     +  PS     S  L+  P      PS+ +  L     G   LQ   +  PSP
Sbjct: 332 CQLATPLPLAPPSPSAPPS--LQTLPSPPATPPSQATTSL-----GSPTLQATHSFLPSP 384

Query: 150 PNSDSGQDAHPDPDANPDAARMPAEIVVLLDSEDNPSLPKRSRPRGLRPLELPAVPATEP 209
           P S     A P P A P  A  P +          P  P  S P  L PL  P+ P    
Sbjct: 385 PLSPL---ATPPPQAPPALALPPLQA---------PPSPPASPP--LSPLATPS-PQAPN 429

Query: 210 GNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPSPDSPTETFAAPAEVRHFTDGS 269
                  Q    PP   PV+     P +  + P   PPS  +P    A P +V      S
Sbjct: 430 ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS-QAPPSLAAPPLQVPPSPPAS 488

Query: 270 FPAGFVLQLFSHTQLRGPDSKDSPKDREVAEGGLPRAESPSPAPPPGLRGTLDLQVIRVR 329
            P                                P A  P  APPP       LQ+ +  
Sbjct: 489 PPMS------------------------------PSATPPPQAPPP--LAAPPLQLAKPP 516

Query: 330 MEEPPAVS 337
            + PPA++
Sbjct: 517 PQAPPALA 524



 Score = 34.3 bits (77), Expect = 0.19
 Identities = 54/213 (25%), Positives = 73/213 (34%), Gaps = 28/213 (13%)

Query: 136 VALLQDVRAEQPSPPN-----SDSGQDAHPDPDANPDAARMPAEIVVL-------LDSED 183
           V L +   + +P PP      S S    H   + +P A R P+    L       L S  
Sbjct: 187 VGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA 246

Query: 184 NP-SLPKRSRPRGLRPLELPAVPATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDP 242
            P S P RS P        PA     P   KP+G +   PP   P RK    P    L  
Sbjct: 247 TPLSSPARSGPSARGTPRAPA----HPSQPKPKGLQALRPPQVTPPRKD-AAPALGPLSS 301

Query: 243 DP-EPPSPDSPTETFAAPAEVRHFTDGSFPAGFVLQLFSHTQLRGPDSKDSPKDREVAEG 301
            P   PSP +  ++ A P            +    QL +   L  P S  +P   +    
Sbjct: 302 SPLATPSPSAALQSQAPPT----LPATPHSSSLTCQLATPLPL-APPSPSAPPSLQT--- 353

Query: 302 GLPRAESPSPAPPPGLRGTLDLQVIRVRMEEPP 334
            LP   +  P+      G+  LQ     +  PP
Sbjct: 354 -LPSPPATPPSQATTSLGSPTLQATHSFLPSPP 385


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 54/199 (27%), Positives = 70/199 (35%), Gaps = 39/199 (19%)

Query: 145 EQPSPPNSDSGQDAHPDPDANPDAARMPAEIVV-----------LLDSEDNPSLPKRSRP 193
           + P P  +   Q A P P A P  A  P + +               S   P  P  + P
Sbjct: 461 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 520

Query: 194 RGLRP------LELPAVPATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPP 247
               P      L++P  P   P  + PR      PP   P     G  +T  L P P PP
Sbjct: 521 PQAPPVLAAPLLQVPPSPPASPTLQAPR-----RPPTPGPDTSVSGPRLTLALAPGPPPP 575

Query: 248 SPDSPTETFAAPAEVRHFTDGSFPAGFVLQLFSHTQLRGPDS-------KDSPKDREVAE 300
              SP+ T + P    H +  +          +  +LRG DS          P D E+A 
Sbjct: 576 PSRSPSSTLSGPDLAGHSSSAT---------STPEELRGYDSGPEGGAAASPPPDAELA- 625

Query: 301 GGLPRAESPSPAPPPGLRG 319
              P A S  PAPP   RG
Sbjct: 626 ACHPAAWSRGPAPPLAFRG 644



 Score = 36.2 bits (82), Expect = 0.050
 Identities = 38/134 (28%), Positives = 51/134 (38%), Gaps = 20/134 (14%)

Query: 136 VALLQDVRAEQPSPPN-----SDSGQDAHPDPDANPDAARMPAEIVVL-------LDSED 183
           V L +   + +P PP      S S    H   + +P A R P+    L       L S  
Sbjct: 178 VGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA 237

Query: 184 NP-SLPKRSRPRGLRPLELPAVPATEPGNKKPRGQRWKEPPGEEPVRKKRG---RPMTKN 239
            P S P RS P        PA     P   KP+G +   PP   P RK       P++ +
Sbjct: 238 TPLSSPARSGPSARGTPRAPA----HPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 293

Query: 240 LDPDPEPPSPDSPT 253
               P P +P SP+
Sbjct: 294 PLATPSPSAPPSPS 307



 Score = 33.5 bits (75), Expect = 0.33
 Identities = 53/205 (25%), Positives = 66/205 (32%), Gaps = 48/205 (23%)

Query: 133 SEGVALLQDVRAEQPSPPNSDSGQDAHPDPDANPDAARMPAEIVVLLDSEDNPSLPKRSR 192
           S G   LQ   +  PSPP S     A P P A P  A  P +          P  P  S 
Sbjct: 329 SLGSPTLQATHSFLPSPPLSPL---ATPPPQAPPALALPPLQA---------PPSPPASP 376

Query: 193 PRGLRPLELPAVPATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPSPDSP 252
           P  L PL  P+ P           Q    PP   PV+     P +  + P   PPS  +P
Sbjct: 377 P--LSPLATPS-PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS-QAP 432

Query: 253 TETFAAPAEVRHFTDGSFPAGFVLQLFSHTQLRGPDSKDSPKDREVAEGGLPRAESPSPA 312
               A P +V      S P                                P A  P  A
Sbjct: 433 PSLAAPPLQVPPSPPASPPMS------------------------------PSATPPPQA 462

Query: 313 PPPGLRGTLDLQVIRVRMEEPPAVS 337
           PPP       LQ+ +   + PPA++
Sbjct: 463 PPP--LAAPPLQLAKPPPQAPPALA 485


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 62/309 (20%), Positives = 113/309 (36%), Gaps = 27/309 (8%)

Query: 20  EEGEDEEEAMVVAVIPRPEPMLRVTQQEKTPPPRPSPLEAGSDGCEEP--KQQVSWEQEF 77
           +E   +++ +V     +PE +++   Q++ P P P     G D  ++    + +S +Q  
Sbjct: 186 QEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPE 245

Query: 78  LVGSSPGGSGRALCMVCGAEIRAPSADTARSHILEQHPHTLDLSPSEKSNILEAWSEGVA 137
            + S P G+G+         I+ P+      H             +++++I+   S   +
Sbjct: 246 KIKSQPPGTGKP--------IQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPS 297

Query: 138 LLQDVRA--EQPSPPNSDSGQDAHPDPDANPDAARMPAE---IVVLLDSEDNPSLPKRSR 192
           L    +   +QP+P    + Q  H    + P  A+ PA+   +   L  +     P    
Sbjct: 298 LPSPSKPPIQQPTPGKPPAQQPGHEK--SQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQP 355

Query: 193 PRGLRPLELPAVPATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPSPDSP 252
           P   +P   P  PA  P  +       ++P  E+P  K   +P      P  +P     P
Sbjct: 356 PGTTKPPAQPLGPAKPPAQQTGS----EKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPP 411

Query: 253 TETFAAPAEVRHFTDGSFPAGFVLQLFSHTQLRGPD----SKDSPKDREVAEGG--LPRA 306
           T+    P  +        PA       +  Q  GP      +  P      + G   P +
Sbjct: 412 TQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPS 471

Query: 307 ESPSPAPPP 315
           + P PA PP
Sbjct: 472 QLPGPAKPP 480



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 57/240 (23%), Positives = 90/240 (37%), Gaps = 33/240 (13%)

Query: 150  PNSDSGQDAHPDPDANPDAARMPAEIVVLLDSEDNPSLPKRSRPRGLRPLELPAVPATEP 209
            P SDS   +HP P +     +      V    E   +  K S     +P+  P    T P
Sbjct: 824  PASDSKIISHPGPSSESKGQKQVDP--VQKKEEPKKAQTKMSPKPDAKPM--PKGSPTPP 879

Query: 210  GNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPS--PDSPTETFAAPAEVRHFTD 267
            G +   GQ    P  + P  +++ R  + NL    + P   P +P ET       + F  
Sbjct: 880  GPRPTAGQTVPTPQ-QSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTG----KLFGF 934

Query: 268  GSFPAGFVLQLFSHTQLRGPDSKDSPKDREVAEGGLPRAESPSPAPPPGLRG-------- 319
            G+        L S     GP S+  P        G P  ++P+P+ PP  +G        
Sbjct: 935  GASIFSQASNLISTAGQPGPHSQSGP--------GAPMKQAPAPSQPPTSQGPPKSTGQA 986

Query: 320  -TLDLQVIRVRME-EPPAVSLLQDWSRHPQGTKRVGAGDTSDWPTVLSESSTTVAGKPEK 377
                 + I V+ E + PA   L+  +      KR    +T   P  + +S +  A +P+K
Sbjct: 987  PPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRT---ETEKKPPPIKDSKSLTA-EPQK 1042



 Score = 34.7 bits (78), Expect = 0.15
 Identities = 57/261 (21%), Positives = 95/261 (36%), Gaps = 49/261 (18%)

Query: 39   PMLRVTQQEKTPPPRPSPLEAGSDGCEEPKQQVSWEQEFLVGSSPGGSGRALCMVCGAEI 98
            P ++ T+ EK PPP    ++       EP++ V   +   +  SP     + C +C  E+
Sbjct: 1016 PTVKRTETEKKPPP----IKDSKSLTAEPQKAVLPTK---LEKSP--KPESTCPLCKTEL 1066

Query: 99   RAPSADTAR----SHILEQHPHTLDLSPSEKSNILEAW-------SEGVA-LLQDVRAEQ 146
               S D       +    Q  +    +P+     ++ W          ++  L D+R   
Sbjct: 1067 NIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMP 1126

Query: 147  PSP----------PNSDSGQDAHPDPDAN-----PDAARMPAEIVVL------LDSEDNP 185
            P+P          P   S Q     P            +  AE V+L      L  E  P
Sbjct: 1127 PAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIP 1186

Query: 186  SLPKRSRPRGLRPLELPAVPATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPE 245
             +    + +    LE     A +   KKP  +  K  P EE +R +  +P+ +   P PE
Sbjct: 1187 PMVTTDQKQEESKLEKDKASALQ--EKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPE 1244

Query: 246  PPS--PDSPTETFAAPAEVRH 264
                 P++ T   +AP E +H
Sbjct: 1245 DKKLLPEAKT---SAPEEQKH 1262



 Score = 33.1 bits (74), Expect = 0.43
 Identities = 47/212 (22%), Positives = 78/212 (36%), Gaps = 21/212 (9%)

Query: 50  PPPRPSPLE---AGSDGCEEPKQQVSWEQEFLVGSSPGGSGRALCMVCGAEIRAPSADTA 106
           PP +PS L    A   G  +P  Q     +    + P G  +      G+E   PS++  
Sbjct: 331 PPAQPSGLTKPLAQQPGTVKPPVQPPGTTK--PPAQPLGPAKPPAQQTGSE--KPSSEQP 386

Query: 107 RSHILEQHPHTLDLSPSEKSNILEAWSEGVALLQDVRAEQPSPPNSDSGQDAHPDPDANP 166
               L Q P  +  +P+++    +  ++ V   + + A+QP   +          P   P
Sbjct: 387 GPKALAQPPG-VGKTPAQQPGPAKPPTQQVGTPKPL-AQQPGLQSPAKAPGPTKTPVQQP 444

Query: 167 DAARMPAEIV---VLLDSEDNPSLPKRSRPRGLRPLELPAVPATEPGNKKPRGQRWKEPP 223
              ++PA+          +  P+ P    P   +P      P  +PG  KP  Q   +P 
Sbjct: 445 GPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKP------PPQQPGPAKPPPQ---QPG 495

Query: 224 GEEPVRKKRGRPMTKNLDPDPEPPSPDSPTET 255
             +P  ++ G        P P  PSP  P  T
Sbjct: 496 SAKPPSQQPGSTKPPPQQPGPAKPSPQQPGST 527


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 62/309 (20%), Positives = 113/309 (36%), Gaps = 27/309 (8%)

Query: 20  EEGEDEEEAMVVAVIPRPEPMLRVTQQEKTPPPRPSPLEAGSDGCEEP--KQQVSWEQEF 77
           +E   +++ +V     +PE +++   Q++ P P P     G D  ++    + +S +Q  
Sbjct: 186 QEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPE 245

Query: 78  LVGSSPGGSGRALCMVCGAEIRAPSADTARSHILEQHPHTLDLSPSEKSNILEAWSEGVA 137
            + S P G+G+         I+ P+      H             +++++I+   S   +
Sbjct: 246 KIKSQPPGTGKP--------IQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPS 297

Query: 138 LLQDVRA--EQPSPPNSDSGQDAHPDPDANPDAARMPAE---IVVLLDSEDNPSLPKRSR 192
           L    +   +QP+P    + Q  H    + P  A+ PA+   +   L  +     P    
Sbjct: 298 LPSPSKPPIQQPTPGKPPAQQPGHEK--SQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQP 355

Query: 193 PRGLRPLELPAVPATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPSPDSP 252
           P   +P   P  PA  P  +       ++P  E+P  K   +P      P  +P     P
Sbjct: 356 PGTTKPPAQPLGPAKPPAQQTGS----EKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPP 411

Query: 253 TETFAAPAEVRHFTDGSFPAGFVLQLFSHTQLRGPD----SKDSPKDREVAEGG--LPRA 306
           T+    P  +        PA       +  Q  GP      +  P      + G   P +
Sbjct: 412 TQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPS 471

Query: 307 ESPSPAPPP 315
           + P PA PP
Sbjct: 472 QLPGPAKPP 480



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 57/240 (23%), Positives = 90/240 (37%), Gaps = 33/240 (13%)

Query: 150  PNSDSGQDAHPDPDANPDAARMPAEIVVLLDSEDNPSLPKRSRPRGLRPLELPAVPATEP 209
            P SDS   +HP P +     +      V    E   +  K S     +P+  P    T P
Sbjct: 824  PASDSKIISHPGPSSESKGQKQVDP--VQKKEEPKKAQTKMSPKPDAKPM--PKGSPTPP 879

Query: 210  GNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPS--PDSPTETFAAPAEVRHFTD 267
            G +   GQ    P  + P  +++ R  + NL    + P   P +P ET       + F  
Sbjct: 880  GPRPTAGQTVPTPQ-QSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTG----KLFGF 934

Query: 268  GSFPAGFVLQLFSHTQLRGPDSKDSPKDREVAEGGLPRAESPSPAPPPGLRG-------- 319
            G+        L S     GP S+  P        G P  ++P+P+ PP  +G        
Sbjct: 935  GASIFSQASNLISTAGQPGPHSQSGP--------GAPMKQAPAPSQPPTSQGPPKSTGQA 986

Query: 320  -TLDLQVIRVRME-EPPAVSLLQDWSRHPQGTKRVGAGDTSDWPTVLSESSTTVAGKPEK 377
                 + I V+ E + PA   L+  +      KR    +T   P  + +S +  A +P+K
Sbjct: 987  PPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRT---ETEKKPPPIKDSKSLTA-EPQK 1042



 Score = 34.7 bits (78), Expect = 0.15
 Identities = 57/261 (21%), Positives = 95/261 (36%), Gaps = 49/261 (18%)

Query: 39   PMLRVTQQEKTPPPRPSPLEAGSDGCEEPKQQVSWEQEFLVGSSPGGSGRALCMVCGAEI 98
            P ++ T+ EK PPP    ++       EP++ V   +   +  SP     + C +C  E+
Sbjct: 1016 PTVKRTETEKKPPP----IKDSKSLTAEPQKAVLPTK---LEKSP--KPESTCPLCKTEL 1066

Query: 99   RAPSADTAR----SHILEQHPHTLDLSPSEKSNILEAW-------SEGVA-LLQDVRAEQ 146
               S D       +    Q  +    +P+     ++ W          ++  L D+R   
Sbjct: 1067 NIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMP 1126

Query: 147  PSP----------PNSDSGQDAHPDPDAN-----PDAARMPAEIVVL------LDSEDNP 185
            P+P          P   S Q     P            +  AE V+L      L  E  P
Sbjct: 1127 PAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIP 1186

Query: 186  SLPKRSRPRGLRPLELPAVPATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPE 245
             +    + +    LE     A +   KKP  +  K  P EE +R +  +P+ +   P PE
Sbjct: 1187 PMVTTDQKQEESKLEKDKASALQ--EKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPE 1244

Query: 246  PPS--PDSPTETFAAPAEVRH 264
                 P++ T   +AP E +H
Sbjct: 1245 DKKLLPEAKT---SAPEEQKH 1262



 Score = 33.1 bits (74), Expect = 0.43
 Identities = 47/212 (22%), Positives = 78/212 (36%), Gaps = 21/212 (9%)

Query: 50  PPPRPSPLE---AGSDGCEEPKQQVSWEQEFLVGSSPGGSGRALCMVCGAEIRAPSADTA 106
           PP +PS L    A   G  +P  Q     +    + P G  +      G+E   PS++  
Sbjct: 331 PPAQPSGLTKPLAQQPGTVKPPVQPPGTTK--PPAQPLGPAKPPAQQTGSE--KPSSEQP 386

Query: 107 RSHILEQHPHTLDLSPSEKSNILEAWSEGVALLQDVRAEQPSPPNSDSGQDAHPDPDANP 166
               L Q P  +  +P+++    +  ++ V   + + A+QP   +          P   P
Sbjct: 387 GPKALAQPPG-VGKTPAQQPGPAKPPTQQVGTPKPL-AQQPGLQSPAKAPGPTKTPVQQP 444

Query: 167 DAARMPAEIV---VLLDSEDNPSLPKRSRPRGLRPLELPAVPATEPGNKKPRGQRWKEPP 223
              ++PA+          +  P+ P    P   +P      P  +PG  KP  Q   +P 
Sbjct: 445 GPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKP------PPQQPGPAKPPPQ---QPG 495

Query: 224 GEEPVRKKRGRPMTKNLDPDPEPPSPDSPTET 255
             +P  ++ G        P P  PSP  P  T
Sbjct: 496 SAKPPSQQPGSTKPPPQQPGPAKPSPQQPGST 527


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 91/342 (26%), Positives = 116/342 (33%), Gaps = 67/342 (19%)

Query: 35   PRPE-PMLRVTQQEKTPPPRPSPLEAGSDGCEEPKQQVSWEQEFLVGSSPGGSGRALCMV 93
            PR E P L    +E    PRP          EEP      E+  L   SP      LC V
Sbjct: 736  PRSEGPHLSPRPEEPHLSPRP----------EEPHLSPQAEEPHL---SPQPEEPCLCAV 782

Query: 94   CGAEIRAPSADTARSHILEQHPHTLDLSPSEKSNILEAWSEGVALLQDVRAEQPSPPNSD 153
                  +P A+      L   P  L LSP  +   L    E   L        P P  S 
Sbjct: 783  PEEPHLSPQAEGPH---LSPQPEELHLSPQTEEPHLSPVPEEPCL-------SPQPEESH 832

Query: 154  -SGQDAHPDPDANPDAARMPAEIVVLLDSEDNPSLPKRSRP-----RGLRPLELPAVPAT 207
             S Q   P     P+ + +  E+      E  P  P+  +P     +   P ELP  P  
Sbjct: 833  LSPQSEEPCLSPRPEESHLSPEL------EKPPLSPRPEKPPEEPGQCPAPEELPLFPPP 886

Query: 208  -EPGNKKPRGQRWKEPPGEEPVR--------KKRGRPMTKN--LDPDPEPPSPDSPTETF 256
             EP      G+     PGE P+            G P      + PDP PP P SP  T 
Sbjct: 887  GEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPP-PLSPIITA 945

Query: 257  AAPAEVRHFTDGSFPAGFVLQLFSHTQLRGPDSKDSPKDREVAEGGL---PRAE--SPSP 311
            AAP  +    +  +P G           +G    +SP    + E  +   P A    P P
Sbjct: 946  AAPPALSPLGELEYPFG----------AKGDSDPESPLAAPILETPISPPPEANCTDPEP 995

Query: 312  APP---PGLRGTLDLQVIRVRMEE-PPAVSLLQDWSRHPQGT 349
             PP   P   G+       + ME  PP  S L   S  PQ +
Sbjct: 996  VPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNS 1037



 Score = 34.3 bits (77), Expect = 0.19
 Identities = 59/232 (25%), Positives = 83/232 (35%), Gaps = 42/232 (18%)

Query: 120 LSPSEKSNILEAWSEGVALLQDVRAEQPSPPNSDSG-----QDAHPDPDANPDAARMPAE 174
           LSP  + + L    E         A + SPP  DS      +D+   P        +P E
Sbjct: 662 LSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLE 721

Query: 175 IVVLLDSEDNPSLPKRSRPRGLRPLELPAVPATEPGNKKPRGQRWKEPPGEEPVRKKRGR 234
              LL   + P L  RS    L P   P  P   P  ++P       P  EEP       
Sbjct: 722 ESPLLPLPEEPQLCPRSEGPHLSP--RPEEPHLSPRPEEPH----LSPQAEEP------- 768

Query: 235 PMTKNLDPDPEPPSPDS-PTETFAAP-AEVRHFTDGSFPAGFVLQLFSHTQ-------LR 285
               +L P PE P   + P E   +P AE  H +    P    L L   T+         
Sbjct: 769 ----HLSPQPEEPCLCAVPEEPHLSPQAEGPHLS----PQPEELHLSPQTEEPHLSPVPE 820

Query: 286 GPDSKDSPKDREVAEGGLPRAESPSPAPPP---GLRGTLDLQVIRVRMEEPP 334
            P     P++  ++    P++E P  +P P    L   L+   +  R E+PP
Sbjct: 821 EPCLSPQPEESHLS----PQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPP 868



 Score = 33.9 bits (76), Expect = 0.25
 Identities = 62/277 (22%), Positives = 96/277 (34%), Gaps = 78/277 (28%)

Query: 24   DEEEAMVVAVIPRPEPMLRVTQQEKT--PPPRPSPLEAGSDGCEEPKQQVSWEQEFLVGS 81
            D+  +M   ++   +PML    Q  T   PP+P P+                     + S
Sbjct: 4143 DQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPV---------------------LQS 4181

Query: 82   SPGGSGRALCMVCGAEIRAPSADTARSHILEQHPHTLDLSPSEKSNILEAWSEGVALLQD 141
              G  G  +    G ++RA         +L ++P    LSP ++  +     +    LQ 
Sbjct: 4182 GQGLPGVGIMPTVG-QLRAQLQG-----VLAKNPQLRHLSPQQQQQLQALLMQ--RQLQQ 4233

Query: 142  VRAEQPSPPNSDSGQDAHP---------------DPDANP-----------DAARMPAEI 175
             +A + +PP  + G    P                P   P              R+PA  
Sbjct: 4234 SQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPP 4293

Query: 176  VVLLDSED----NPSLPKRSRPRGLRPLELPA----------VPATEPGNKKPRGQRWKE 221
              L         +P+ P  S     RP +LP+          +P T PG  KP+G   + 
Sbjct: 4294 GALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEP 4353

Query: 222  PPGE-EPVRKKRGRPM-TKNLDP-DPEPPSPDSPTET 255
            PPG   P   +    + +K L P DP    PD+  ET
Sbjct: 4354 PPGRVSPAAAQLADTLFSKGLGPWDP----PDNLAET 4386



 Score = 33.5 bits (75), Expect = 0.33
 Identities = 60/264 (22%), Positives = 84/264 (31%), Gaps = 20/264 (7%)

Query: 80  GSSPGGSGRALCMVCGAEIRAPSADTARSHILEQHPHTLDLSPSEKSNI-----LEA-WS 133
           G +P     AL + C  + +     + +    E  P   +  P  K+ +     LEA  +
Sbjct: 378 GDTPTDEPDALYVACQGQPKGGHVTSMQPK--EPGPLQCEAKPLGKAGVQLEPQLEAPLN 435

Query: 134 EGVALLQDVRAEQPSPPNSDSGQDAHPDPDAN---PDAARMPAEIVVLLDSEDNPSLPKR 190
           E + LL        SPP  +S     P P+A+   P    +PA     L    + S P  
Sbjct: 436 EEMPLLPPPEESPLSPPPEES--PTSPPPEASRLSPPPEELPASP---LPEALHLSRPLE 490

Query: 191 SRPRGLRPLELPAVPATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPSPD 250
             P    P E P  P  E     P  +    PP E P       P++    P+  P SP 
Sbjct: 491 ESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSP--PPEASPLSPP 548

Query: 251 SPTETFAAPAEVRHFTDGSFPAGFVLQLFSHTQLRGPDSKDSPKDREVAEGGLPRAESPS 310
                 + P E         P    L          P  ++SP         L      S
Sbjct: 549 FEESPLSPPPE--ELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEES 606

Query: 311 PAPPPGLRGTLDLQVIRVRMEEPP 334
           P  PP     L       R+  PP
Sbjct: 607 PLSPPPEESPLSPPPEASRLSPPP 630



 Score = 33.1 bits (74), Expect = 0.43
 Identities = 64/272 (23%), Positives = 97/272 (35%), Gaps = 50/272 (18%)

Query: 66   EPKQQVSWEQEFLVGSSPGGSGRALCMVCGAEIRAPSADTARSHILEQHPHTLDLSPSEK 125
            E ++ +  ++E L  SSP      L  V      +PS+ T    +  + P       + +
Sbjct: 2280 ESRKALEVKKEELGASSPSYGPPNLGFV-----DSPSSGTHLGGLELKTPDVFKAPLTPR 2334

Query: 126  SNILEAWSEGVALLQDVRAEQPSPPNSDSGQDAHPDPDANPDAARMPAEIVVLLDSEDNP 185
            ++ +E  S G+ L    R ++P P      Q   P P ++PD  R  +      D    P
Sbjct: 2335 ASQVEPQSPGLGL----RPQEPPP-----AQALAPSPPSHPDIFRPGS----YTDPYAQP 2381

Query: 186  SLPKRSRPR------GLRPLELPA-----VPATEPGNKKPRGQRWKEPPGEEPVRKKRGR 234
             L  R +P        L P  LP+     VPA+       +      P   E        
Sbjct: 2382 PLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVT 2441

Query: 235  PMTKNLDPDPEPPSPDSPTETFA--------APAEVRHFTDGSFPAGFVLQLFSHTQLRG 286
            P  ++ DP   PPS     + FA         P EV      +F AG +    +HT L  
Sbjct: 2442 PRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEV------AFKAGSL----AHTSL-- 2489

Query: 287  PDSKDSPKDREVAEGGLPRAESPSPAPPPGLR 318
              +   P        G   A+ PS  PP  +R
Sbjct: 2490 -GAGGFPAALPAGPAGELHAKVPSGQPPNFVR 2520



 Score = 32.0 bits (71), Expect = 0.95
 Identities = 32/105 (30%), Positives = 42/105 (40%), Gaps = 16/105 (15%)

Query: 122  PSEKSNILEAWSEGVALLQDVRAEQPSPPNSDSGQDAHPDPDANPDAARMPAEIVVLLDS 181
            P++ S      +  V  L     E+PSPP         P P A P  A  P E +V L +
Sbjct: 4889 PTQHSYTYNVSNLDVRQLSAPPPEEPSPP---------PSPLA-PSPASPPTEPLVELPT 4938

Query: 182  EDN-----PS-LPKRSRPRGLRPLELPAVPATEPGNKKPRGQRWK 220
            E       PS LP  S P   RP      P     ++ PR ++WK
Sbjct: 4939 EPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLKKWK 4983



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 52/193 (26%), Positives = 64/193 (33%), Gaps = 45/193 (23%)

Query: 160  PDPDANPDAARMPAEIVVLLDSEDNP----------SLPKRSRPRGLRPLELPAVPATEP 209
            PDP + P +     +    L     P          SL   S   G  P  LPA PA E 
Sbjct: 2447 PDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGEL 2506

Query: 210  GNKKPRGQ--RWKEPPG-------EEPVR----KKRGRPMTKNLDPDPEPPSPD------ 250
              K P GQ   +   PG         P+R    +  G P  K   P P  P P       
Sbjct: 2507 HAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHF 2566

Query: 251  SPTETFAAPAEVRH-FTDGSF-PAGFVLQLFSHTQLRGPDSKDSPKDREVAEGGLPRAES 308
             P  T   P    +    G+F P+G  L         GP S  + +       GL     
Sbjct: 2567 GPGPTLGKPQSTNYTVATGNFHPSGSPL---------GPSSGSTGESY-----GLSPLRP 2612

Query: 309  PSPAPPPGLRGTL 321
            PS  PPP   G+L
Sbjct: 2613 PSVLPPPAPDGSL 2625


>gi|54860079 nadrin isoform 1 [Homo sapiens]
          Length = 881

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 57/243 (23%), Positives = 84/243 (34%), Gaps = 33/243 (13%)

Query: 35  PRPEPMLRVTQQEKTPPPRPSPLEAGSDGCEEPKQQVSWEQEFLVGSSPGGSGRALCMVC 94
           P P  + R  ++    PP+P     G  G +               SS G S     +  
Sbjct: 624 PSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQ---------------SSSGTSQHPPSLSP 668

Query: 95  GAEIRAPSADTARSHILEQHPHTLDLSPSEKSNIL--EAWSEGVALLQDVRAEQPSPPNS 152
               R+PS  T       QH       PS  S +     +S  ++ +Q      P PP  
Sbjct: 669 KPPTRSPSPPT-------QHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQ 721

Query: 153 DSG-QDAHPDPDANPDAARMPAEIVVLLDSEDNPSLPK--RSRPRGLRPLELPAVPATEP 209
            +      P+    P+   +P+E  +   S   P  P    + P G +   LPA      
Sbjct: 722 ATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAG 781

Query: 210 GNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPSPDSPTE---TFAAPAEVRHFT 266
           GN +         P   PV K R RP   ++ P P+PP   S  +   T  AP   +  T
Sbjct: 782 GNPETAQPHAGTLPRPRPVPKPRNRP---SVPPPPQPPGVHSAGDSSLTNTAPTASKIVT 838

Query: 267 DGS 269
           D +
Sbjct: 839 DSN 841


>gi|54860105 nadrin isoform 2 [Homo sapiens]
          Length = 803

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 57/243 (23%), Positives = 84/243 (34%), Gaps = 33/243 (13%)

Query: 35  PRPEPMLRVTQQEKTPPPRPSPLEAGSDGCEEPKQQVSWEQEFLVGSSPGGSGRALCMVC 94
           P P  + R  ++    PP+P     G  G +               SS G S     +  
Sbjct: 546 PSPHTLRRAVKKPAPAPPKPGNPPPGHPGGQ---------------SSSGTSQHPPSLSP 590

Query: 95  GAEIRAPSADTARSHILEQHPHTLDLSPSEKSNIL--EAWSEGVALLQDVRAEQPSPPNS 152
               R+PS  T       QH       PS  S +     +S  ++ +Q      P PP  
Sbjct: 591 KPPTRSPSPPT-------QHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQ 643

Query: 153 DSG-QDAHPDPDANPDAARMPAEIVVLLDSEDNPSLPK--RSRPRGLRPLELPAVPATEP 209
            +      P+    P+   +P+E  +   S   P  P    + P G +   LPA      
Sbjct: 644 ATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAG 703

Query: 210 GNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPSPDSPTE---TFAAPAEVRHFT 266
           GN +         P   PV K R RP   ++ P P+PP   S  +   T  AP   +  T
Sbjct: 704 GNPETAQPHAGTLPRPRPVPKPRNRP---SVPPPPQPPGVHSAGDSSLTNTAPTASKIVT 760

Query: 267 DGS 269
           D +
Sbjct: 761 DSN 763


>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
          Length = 825

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 67/268 (25%), Positives = 111/268 (41%), Gaps = 36/268 (13%)

Query: 96  AEIRAPSADTARSHILEQHPHTLDLSPSEKSNILEAWSEGVALL-------QDVRAEQPS 148
           AE+++PSA   +   +E+ P  L   PS +    E  S  + LL       ++  AE   
Sbjct: 557 AEVQSPSA---KGVSIEEAPLELQ-PPSGEETTAEEASAAIQLLAATEASAEEAPAEVQP 612

Query: 149 PPNSDSGQDAHPDPDANPDAARMPAEIVVLLDSEDNPSLPKRSRPRGLRPLELPAVPATE 208
           PP  ++  +  P P     A   PAE+     +E+ P+   +  P    P E+   PA E
Sbjct: 613 PPAEEAPAEVQPPP-----AEEAPAEVQPP-PAEEAPA-EVQPPPAEEAPAEVQPPPAEE 665

Query: 209 -PGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPSPDSPTETFAA-----PAEV 262
            P   +P     +E P E         P+ + L     PP+ D P E  +      PA++
Sbjct: 666 APAEVQPPPA--EEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADL 723

Query: 263 RHFTDGSFPAGFVLQLFSHTQLRGPDSKDSPKDREVAEGGLPRAESPSPAPPPGLR-GTL 321
                  FP G      +  ++  P S+ +P+D  + E      +SP  A  P ++ G++
Sbjct: 724 --LLTEEFPIGE-----ASAEVSPPPSEQTPEDEALVENVSTEFQSPQVAGIPAVKLGSV 776

Query: 322 DLQVIRVRMEEPPAV-SLLQDWSRHPQG 348
            L+    + EE   + S+L+D S    G
Sbjct: 777 VLEG-EAKFEEVSKINSVLKDLSNTNDG 803



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 60/294 (20%), Positives = 99/294 (33%), Gaps = 49/294 (16%)

Query: 44  TQQEKTPPPRPSPLEAGSDGCEEPKQQVSWEQEFLVGSSPGGSGRALCMVCGAEIRAPSA 103
           T  E+ P    SPL       E   ++ S E + L  + P            AE R+P +
Sbjct: 448 TPAEEAPTEFQSPLPK-----ETTAEEASAEIQLLAATEPPADETP------AEARSPLS 496

Query: 104 DTA---RSHILEQHPHTLDLSPSEKSNILEAWSEGVALLQDVRAEQPSPPNSDSGQDAHP 160
           +      +H   Q P   + +  E S  ++  +   A   +  AE  SP + ++  +  P
Sbjct: 497 EETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAP 556

Query: 161 DPDANPDAARMPAEIVVL--------------------------LDSEDNPSLPKRSRPR 194
               +P A  +  E   L                            +E+ P+   +  P 
Sbjct: 557 AEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPA-EVQPPPA 615

Query: 195 GLRPLELPAVPATE-PGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPSPDSPT 253
              P E+   PA E P   +P       PP EE   + +  P  +       PP+ ++P 
Sbjct: 616 EEAPAEVQPPPAEEAPAEVQP-------PPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPA 668

Query: 254 ETFAAPAEVRHFTDGSFPAGFVLQLFSHTQLRGPDSKDSPKDREVAEGGLPRAE 307
           E    PAE       S PA       +   +  P + D P +    +   P A+
Sbjct: 669 EVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPAD 722



 Score = 28.9 bits (63), Expect = 8.0
 Identities = 36/143 (25%), Positives = 54/143 (37%), Gaps = 22/143 (15%)

Query: 221 EPPGEEPVRKKRGRPMTKNLDPDPEP-----------PSPDSPTETFAAPAEVRHFTDGS 269
           EPP  E    K   P+ +      EP           PS +   +  AA A   +     
Sbjct: 258 EPPSTEKFPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQ 317

Query: 270 FPAGFVLQLFSH-TQLRGPDSKDSPKDREVAEGGLPRA-ESPSPAPPPGLRGTLDLQVIR 327
            P      L     +++ P +++SP    +AE   P A ESPS  PP         +++ 
Sbjct: 318 PPPAEEAPLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPP--------AEILP 369

Query: 328 VRMEEPPAVSLLQDWSRHPQGTK 350
              E+ P+V LL +  R P   K
Sbjct: 370 PPAEKSPSVELLGE-IRSPSAQK 391


>gi|42475970 synapse defective 1, Rho GTPase, homolog 1 [Homo
           sapiens]
          Length = 735

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 41/159 (25%), Positives = 65/159 (40%), Gaps = 24/159 (15%)

Query: 146 QPSPPNSD----SGQDAHPDPDANPDAARMPAEIVVLLDSEDNPSLPKRSRPRGLRPLEL 201
           +PSPP  +     G  A  +  ++P+A+R PA    L   E +    +R    G +P E 
Sbjct: 37  EPSPPEPEPQAPEGSQAGAEGPSSPEASRSPARGAYLQSLEPSS---RRWVLGGAKPAED 93

Query: 202 PAVPATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPSPDSPTETFAAPAE 261
            ++    PG  +P G+ W  P  EE                DP PP+P+ P     +   
Sbjct: 94  TSLGPGVPGTGEPAGEIWYNPIPEE----------------DPRPPAPEPPGPQPGSAES 137

Query: 262 VRHFTDGSFPAGFVLQLFSHTQLRGPDSKDSPKDREVAE 300
                 G+ PA    +  S T+  GP  + S K +++ E
Sbjct: 138 EGLAPQGAAPASPPTKA-SRTKSPGPARRLSIKMKKLPE 175


>gi|118498339 EMI domain containing 2 [Homo sapiens]
          Length = 439

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 55/198 (27%), Positives = 76/198 (38%), Gaps = 18/198 (9%)

Query: 123 SEKSNILEAWSEGVALLQDVRAEQPSPPNSDSGQDAHPDPDANPDAARMPAEIVVLLDSE 182
           SE+   LEA    V LL+   AE+PS P++D        P  N D   +P  I +   + 
Sbjct: 138 SERLTTLEA---KVLLLE--AAERPSSPDNDLPAPESTPPTWNEDF--LPDAIPL---AH 187

Query: 183 DNPSLPKRSRPRGLRPLELPAVPATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDP 242
             P   + + P G      P  PA  PG+K  RGQ  ++ P   P     G P  + L  
Sbjct: 188 PVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPP--GLLGPPGPRGLPG 245

Query: 243 DPEPPSPDSPTETFAAPAEVRHFTDGSFPAGFVLQLFSHTQLRGPDSKDSPKDREVAEGG 302
           +   P P  P      P         + P G +  L   T     DS+ +    +    G
Sbjct: 246 EMGRPGPPGPPGPAGNPG-----PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAG 300

Query: 303 LPRAES-PSPAPPPGLRG 319
           +P     P P  PPG RG
Sbjct: 301 VPGPRGPPGPPGPPGPRG 318


>gi|239753975 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 389

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 71/243 (29%), Positives = 90/243 (37%), Gaps = 46/243 (18%)

Query: 112 EQHPHTLDLSPSEKSNILEAWSEGV--ALLQDVRAEQPSPPNSDSGQDAHPDPDANPDAA 169
           EQ  H+    P  +      WS      L   V    P+ P S       P P A     
Sbjct: 71  EQRDHSQSSPPCRRLASYSFWSSAPWRELTLPVSPADPAAPPSSPHAPTRPPPQAVQPRP 130

Query: 170 RMPAEIVVLLDSEDNPSLPKRSRPRGL-RPLELPAVPATEPGNKKPRGQRWKEPPGEEPV 228
             P        +  + +LP  S P G  RP  LP  P   P    PR  RW +P    P 
Sbjct: 131 SEP--------TPGSEALPPGSLPEGEPRPYALP--PRESPA---PRPFRWGDPFSPAPP 177

Query: 229 RKKRGRPMTKNLDPDPEPPSPDSPTETFAAPAEVRHFTDGSFP--AGFVLQLFSHTQLRG 286
           R +   P ++   P  +PPS  +    F +P  VR    G  P  A  V  LF     R 
Sbjct: 178 RPQ---PPSR---PAAQPPSRPA----FRSPRPVR----GPHPRRAVVVAVLFGVQAPR- 222

Query: 287 PDSKDSPKDREVAEGGLPR-AESPSPAPPPGLRGTLDLQVIRVRMEEPPAVSLLQDWSRH 345
                    R+VAEGGL R    P  AP  G RG L L V+     + P +   +  SR 
Sbjct: 223 ---------RDVAEGGLRRDGRRPGLAPQRG-RGGLLLVVLHAATVQRPRLG--RGPSRP 270

Query: 346 PQG 348
           P+G
Sbjct: 271 PRG 273


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 54/204 (26%), Positives = 65/204 (31%), Gaps = 34/204 (16%)

Query: 144 AEQPSPPNSDSGQDAH---------------PDPDANPDAARMPAEIVVLLDSEDNPSLP 188
           A  P+PP +  G  A                P P A    AR P        +  +P  P
Sbjct: 106 ATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPG-P 164

Query: 189 KRSRPRGLRPLEL---PAVPATEPGNKKPRGQRWKEPP---GEEPVRKKRGRPMTKNLDP 242
            +  PR  R   L   P  PA  P    P G R   PP     EP      +P       
Sbjct: 165 AQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQ 224

Query: 243 DPEPPSPDSPTETFAAPA----------EVRHFTDGSFPAGFVLQLFSHTQLRGPDSKDS 292
            P PP P  P E  A  A          EV  +  GS  AG  L       L   ++   
Sbjct: 225 QPPPPQPQPPPEGGAVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAAR 284

Query: 293 PKDREVAEG--GLPRAESPSPAPP 314
            +      G   LPR + P  APP
Sbjct: 285 GRLERTRLGALALPRGDRPGRAPP 308


>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
           homolog 2 [Homo sapiens]
          Length = 1210

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 38/168 (22%), Positives = 60/168 (35%), Gaps = 14/168 (8%)

Query: 97  EIRAPSADTARSHILEQHPHTLDLSPSEKSNILEAWSEGVALLQDVRAEQPSPPNSDSGQ 156
           +++   ++ + S    + P +    PS   ++     E VA      AE  S  +SDS  
Sbjct: 426 DLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSL----PEPVASAHSSSAESESTSDSDSSS 481

Query: 157 DAHPDPDANPDAARMPAEIVVLLDSEDNPSLPKRSRPRGLRPLELPAVPATEPGNKKPRG 216
           D+  +  ++      P E        + P+  K      L  +  PA P        P G
Sbjct: 482 DSESESSSSDSEENEPLETPA--PEPEPPTTNKWQLDNWLTKVSQPAAP--------PEG 531

Query: 217 QRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPSPDSPTETFAAPAEVRH 264
            R  EPP   P  K      T     + + P P S ++   AP E  H
Sbjct: 532 PRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPH 579


>gi|41281612 zinc finger protein 828 [Homo sapiens]
          Length = 812

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 74/316 (23%), Positives = 105/316 (33%), Gaps = 52/316 (16%)

Query: 35  PRPEPMLRVTQQE---------KTPPPRPSPLEAGSDGCEEPKQQVSWEQEFLVGSSPGG 85
           P+P P+  +  Q+         +TP P P P +  S    EP + V   +   +   P  
Sbjct: 146 PKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSP 205

Query: 86  SGRALCMVCGAEIRA-------------------PSADTARSHILEQHPHTLDLSPSEKS 126
             +    V    ++A                   PSA +  S +L   P     SP+   
Sbjct: 206 EPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAASP 265

Query: 127 NILEAWSEGVALLQDVRAEQPSPPNSDSGQDAHPDPDANPDAARMPAEIVVLLDSEDNP- 185
                 S   A        +PSP  S+S +   P P  +P+  R PA  V     +  P 
Sbjct: 266 E-----SRKSARTTSPEPRKPSP--SESPEPWKPFPAVSPE-PRRPAPAVSPGSWKPGPP 317

Query: 186 --SLPKRSRPRGLRPLELPAVPA--TEPGNKKP----RGQRWKEPPGEEPVRKKRGRPMT 237
               P +S P        PA PA    PG  KP        WK  P       K     +
Sbjct: 318 GSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASWK-----S 372

Query: 238 KNLDPDPEPPSPDSPTETFAAPAEVRHFTDGSFPAGFVLQLFSHTQLRGPDSKDSPKDRE 297
            ++ P      P SP    + P E+R       P  +        +LR P    SP+ R 
Sbjct: 373 SSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRS 432

Query: 298 VAEGGLPRAESPSPAP 313
            A  G P    PS +P
Sbjct: 433 PA--GSPELRKPSGSP 446



 Score = 33.5 bits (75), Expect = 0.33
 Identities = 74/328 (22%), Positives = 105/328 (32%), Gaps = 73/328 (22%)

Query: 27  EAMVVAVIPRPEPMLRVTQQEKTPPPRPSPLEAGSDGCEEPKQQVSWEQEFLVGSSPGGS 86
           E+  +A +P PEP       +K  P  P  ++A       PK Q        +G     S
Sbjct: 195 ESQKLAPVPSPEP-------QKPAPVSPESVKAT---LSNPKPQKQSHFPETLGPPSASS 244

Query: 87  GRALCMVCGAEIRAPS---ADTARSHILEQHPHTLDLSPSEKSNILEAWSEGVALLQDVR 143
             +  +    E   PS   +  +R       P     SPSE     E W    A+  + R
Sbjct: 245 PESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESP---EPWKPFPAVSPEPR 301

Query: 144 AEQP-------------------SPPNSDSG--QDAHPDPDANP---------------- 166
              P                   S P++ SG  + A P P  +P                
Sbjct: 302 RPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKP 361

Query: 167 ----DAARMPAEIVVLLDSEDNPSLPK--RSRPRGLR-------PLELPAVPATEPGNKK 213
                +A   +  V     +  P+ P+  +S P  LR       P    AVP   P  +K
Sbjct: 362 TPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRK 421

Query: 214 PR---GQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPSP---DSPTETFAAPAEVRHFTD 267
           P        + P G   +RK  G P    L PD    SP   D P    ++         
Sbjct: 422 PGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWK 481

Query: 268 GSFPAGFVLQLFSHTQLRGPDS-KDSPK 294
            SF       +F  T+  GP    +SPK
Sbjct: 482 SSFFIEPQKPVFPETRKPGPSGPSESPK 509



 Score = 32.3 bits (72), Expect = 0.73
 Identities = 44/181 (24%), Positives = 58/181 (32%), Gaps = 30/181 (16%)

Query: 147 PSPPNSDSGQDAH-----PDPDANPDAARMPAEIVVLLDSEDNPSLPKRSR-PRGLRPLE 200
           P PP S    ++      P P+    A   P  +   L    NP   K+S  P  L P  
Sbjct: 185 PEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLS---NPKPQKQSHFPETLGP-- 239

Query: 201 LPAVPATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPSPDSPTETF---- 256
            P+  + E     P      EP G  P      R   +   P+P  PSP    E +    
Sbjct: 240 -PSASSPE----SPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFP 294

Query: 257 AAPAEVRHFTDGSFPAGFVLQLFSHTQLRGPDSKDSP-KDREVAEGGLPRAESPSPAPPP 315
           A   E R       P  +           GP     P K    A  G  +   P+P+  P
Sbjct: 295 AVSPEPRRPAPAVSPGSW---------KPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSP 345

Query: 316 G 316
           G
Sbjct: 346 G 346


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
            sapiens]
          Length = 1560

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 93/408 (22%), Positives = 141/408 (34%), Gaps = 68/408 (16%)

Query: 26   EEAMVVAVIPRPE---------PMLRVTQQEKTPPPRPSPLEAGSDGCEEPKQQ---VSW 73
            E A V+ V P P+         P+     Q + PP  P+P  A       P+      S 
Sbjct: 614  EAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASS 673

Query: 74   EQEFLVGSSPGGSGRALCMVCGAEIRAPSADTARSHILEQHPH-----TLDLS---PSEK 125
             ++ ++G  P  +  A+      ++  P  + ++  +  + PH     ++ +S   P++ 
Sbjct: 674  PEKIVLGQPPSATPTAILTQDSLQMFLPQ-ERSQQPLSAEGPHLSVPASVIVSAPPPAQD 732

Query: 126  SNILEAWSEGVALLQDVRAEQPSPPNSDSGQDAHPDPDANPDAARMPAEIVVLLDSEDNP 185
                   ++G  L       Q SP  +     A P     P ++        L DS   P
Sbjct: 733  PAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLP 792

Query: 186  SL-----PKR--SRPRG---------LRPLELPAVPATEPGNKKPRGQRWKEPPGEEPVR 229
            S      P R  SRP+          L P   P  P T PG    + Q    PP   P  
Sbjct: 793  SPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAP 852

Query: 230  KKRGRPMTKNLDPDPEPPS----------PDSPTETFAAPAEVRHFTDGSFPAGFVLQLF 279
               G P    L P  +PP           P S +   A+ +E         P+ F LQ F
Sbjct: 853  TAPGPPQPP-LRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQ-F 910

Query: 280  SHTQLRGPDSKDSPKDREVAEGGLPRAESPSPAPPPGLRGTLDLQVIRVRMEEPPAVSLL 339
              +Q  GP    +P         L     P+  PPP  R    +      + +P A  LL
Sbjct: 911  PPSQ--GPHKSPTPPPT------LHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKA--LL 960

Query: 340  QDWSRHPQG----TKRVGA-----GDTSDWPTVLSESSTTVAGKPEKG 378
            + + + P G     K  GA       TS  P     +S  V+G+   G
Sbjct: 961  ERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSG 1008



 Score = 30.0 bits (66), Expect = 3.6
 Identities = 31/112 (27%), Positives = 43/112 (38%), Gaps = 19/112 (16%)

Query: 222  PPGEEPVRKKRGRPMTKNLDPDPEPPSPDSP------TETFAAPAEVRHFTDG--SFPAG 273
            PP + P  K    P T +L P+P  P P  P      T  F A  + +   +     P+G
Sbjct: 911  PPSQGP-HKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSG 969

Query: 274  FVLQLFSHTQLRGPDSKDS------PKDREVAEG----GLPRAESPSPAPPP 315
             +LQ  +      P +  S      P    +  G    G P A S +PAP P
Sbjct: 970  IILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAP 1021



 Score = 28.9 bits (63), Expect = 8.0
 Identities = 45/190 (23%), Positives = 70/190 (36%), Gaps = 14/190 (7%)

Query: 179  LDSEDNPSLPKRSRPRGLRPLELPAVPATEPGNKKPRG-QRWKEPPGEEPVRKKRGRPMT 237
            LD++++  +P R+RP  ++  E  +    +   K+  G  +       +PV +    P T
Sbjct: 1281 LDADEDGPMPSRNRPP-IKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPAT 1339

Query: 238  -KNLDPDPEPPSPDSPTETF------AAPAEVRHFTDGSFPAGFVLQLFSHTQLRGPDSK 290
             K  +P P PP P  PT           PA       G+ P    L L    +    ++ 
Sbjct: 1340 LKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYR----ENV 1395

Query: 291  DSPKDREVAEGGLPRAESPSPAPPPGLRGTLDLQVIRVRMEEPPAVSLLQDWSRHPQGTK 350
              P   E    G  R  SP+P P      T  L      +E+     +L+     P  + 
Sbjct: 1396 GGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASA 1455

Query: 351  RVGAGDTSDW 360
              G GD  DW
Sbjct: 1456 AQGTGD-PDW 1464


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 48/194 (24%), Positives = 73/194 (37%), Gaps = 43/194 (22%)

Query: 146 QPSPPNSDSGQDAHPDPDANPDA-----ARMPAEIV--VLLDSEDNPSLPKRSR-----P 193
           +P+ P  D+ +   P P   P A     A +PA  +  V   SE  P LP +S      P
Sbjct: 278 EPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPP 337

Query: 194 RGLRPLELPAVPATEPGNKKPRGQRWKEPPGEEPV--RKKRGRPMTKN--LDPDPEPPSP 249
           +      LPA PA               PPG +P   +K+ GRP      L+P P PP+ 
Sbjct: 338 QKAGAQALPAPPA---------------PPGSQPFLQKKRHGRPGAGGGKLNPPPAPPAR 382

Query: 250 DSPTETFAAPAEVRHFTDGSFPAG------------FVLQLFSHTQLRGPDSKDSPKDRE 297
              TE  +   +   +T    P G            F  +   H+    P   +    ++
Sbjct: 383 SPTTELSSKSQQATAWTPTQQPGGQLRNGSLHIIDDFESKFTFHSVEDFPPPDEYKPCQK 442

Query: 298 VAEGGLPRAESPSP 311
           +    +PR+ +P P
Sbjct: 443 IYPSKIPRSRTPGP 456


>gi|12669915 E2F transcription factor 4 [Homo sapiens]
          Length = 413

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 36/138 (26%), Positives = 53/138 (38%), Gaps = 10/138 (7%)

Query: 30  VVAVIPRPEPMLRVTQQEKTPPPRPSPLEAGSDGCEEPKQQVSWEQEFLVGSS--PGGSG 87
           V   +P PE +L+      TPPP P P  A S     P          + GS+   G +G
Sbjct: 205 VAVPVPPPEDLLQSPSAVSTPPPLPKPALAQSQEASRPNSP-QLTPTAVPGSAEVQGMAG 263

Query: 88  RALCMVCGAEIRAPSADTARSHILEQHPHTLDLSPSEKSNILEAWSEGVALLQDVRAEQP 147
            A  +         S D+     L   P TLD  P + S +L++ S          +   
Sbjct: 264 PAAEITVSGGPGTDSKDSGELSSLPLGPTTLDTRPLQSSALLDSSSSS-------SSSSS 316

Query: 148 SPPNSDSGQDAHPDPDAN 165
           S  NS+S   + P+P  +
Sbjct: 317 SSSNSNSSSSSGPNPSTS 334


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 43/176 (24%), Positives = 60/176 (34%), Gaps = 29/176 (16%)

Query: 147 PSPPNSDSGQDAHPDPDANPDAARMPAEIVVLLDSEDNPSLPKRSRPRGLRPLELPAVPA 206
           PSP +   G+   P  +    + + P+       +   PS P   + +  +        A
Sbjct: 296 PSPASGRRGEGDAPFSEPGTTSTQRPSSPET---ATKQPSSPYEDKDKDKKEKS-----A 347

Query: 207 TEPGNKKPRGQRWKEPPGEEPVRKKR--GRPM---TKNLDPDP-EPPSPDSPTETFAAPA 260
           T P     R     EPP   P+  +R  G P    T  L  +P  PPS  SPT   + P 
Sbjct: 348 TRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPK 407

Query: 261 EVRHFTDGSFPAGFVLQLFSHTQLRGPDSKDSPKDREVAEGGLPRAESPSPAPPPG 316
                   S                   S  SP+  +V+       ESP PAP PG
Sbjct: 408 SPEKLPQSS---------------SSESSPPSPQPTKVSRHASSSPESPKPAPAPG 448



 Score = 29.6 bits (65), Expect = 4.7
 Identities = 54/230 (23%), Positives = 79/230 (34%), Gaps = 52/230 (22%)

Query: 141  DVRAEQPSPPNSDSGQDAHPDPDANPDAARMPAEIVVLLDSEDNPSLPKRSRPRGLRPLE 200
            +V+ +  + P + SG D+ P+P A    A                 LP+RSR        
Sbjct: 1603 EVKDKPRAAPRAQSGSDSSPEPKAPAPRA-----------------LPRRSR-------- 1637

Query: 201  LPAVPATEPGNKKPRGQRWKEPPGEEPVRKKRGR--------PMTKNLDPDPEPPSPDSP 252
              +  +++     P G    E   E P + +  R        P TK+  P     S  SP
Sbjct: 1638 --SGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSP 1695

Query: 253  TETFAAPAEVRHFTDGSFPAGFVLQLFSHTQLRGPDSKDSPKDREVAEGGLPRAESPSP- 311
              T  A    R  +  S P     +  +  + R   S  SP+  E +     R  + SP 
Sbjct: 1696 ELTRKARLSRRSRSASSSPE---TRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPR 1752

Query: 312  ---------APPPGLRGTLDLQVIRVR-MEEPPAVSLLQDWSRHPQGTKR 351
                     +P P  RG   LQ  R R   E    +  +D S   Q T R
Sbjct: 1753 TKTTSRRGRSPSPKPRG---LQRSRSRSRREKTRTTRRRDRSGSSQSTSR 1799


>gi|148806908 fibronectin type III domain containing 1 [Homo sapiens]
          Length = 1894

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 54/225 (24%), Positives = 73/225 (32%), Gaps = 44/225 (19%)

Query: 119  DLSPSEKSNILEAWSEGVALLQDVRAEQPSPPNSDSGQDAHPDPDANPDAARMPAEIVVL 178
            D  P  K + L + ++ V    D   E  SP       D H  P A P AAR        
Sbjct: 935  DTHPQGKYSSLASKAQDVQQSTDADTEGHSPKAQPGSTDRHASP-ARPPAAR-------- 985

Query: 179  LDSEDNPSLPKRSRPRGLRPLELPAVPA-------------------------TEPGNKK 213
              S+ +PS+P+R  P G  P + P  P                          T+ G  +
Sbjct: 986  --SQQHPSVPRRMTP-GRAPQQQPPPPVATSQHHPGPQSRDAGRSPSQPRLSLTQAGRPR 1042

Query: 214  PRGQRWKEPPGEEPVRKKRGRPMT--KNLDPDPEPPSPDSPTETFAAPAEVRHFTDGSFP 271
            P  Q       +      RG   T  +N D D +    D  TE  A   +VR     +  
Sbjct: 1043 PTSQGRSHSSSDPYTASSRGMLPTALQNQDEDAQGSYDDDSTEVEA--QDVRAPAHAARA 1100

Query: 272  AGFVLQLFSHTQLRGPDSKDSPKDREVAEGGLPRAESPSPAPPPG 316
                  L  H Q+  P    +  D     G    A SP+    PG
Sbjct: 1101 KEAAASLPKHQQVESPTGAGAGGDHRSQRG---HAASPARPSRPG 1142


>gi|157785645 SPEG complex locus [Homo sapiens]
          Length = 3267

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 46/177 (25%), Positives = 68/177 (38%), Gaps = 20/177 (11%)

Query: 97  EIRAPSADTARSHILEQHPHTLDLSPSEKSNILEAWSEGVALLQDVRAEQPSPPNSDSGQ 156
           E+RAP +   R  + +Q   +LD    ++S   +        L  +R          S +
Sbjct: 456 ELRAPGSVAERRRLFQQKAASLDERTRQRSPASDLELRFAQELGRIRRSTSREELVRSHE 515

Query: 157 DAHPDPDANPDAARMPAEIVVLLDSEDNPSLPKRSR---PRGLRPLELPAV--PATEPGN 211
                    P + R P E  +       PS PK SR   P   +P    +   P  EPG 
Sbjct: 516 SLRATLQRAP-SPREPGEPPLF----SRPSTPKTSRAVSPAAAQPPSPSSAEKPGDEPGR 570

Query: 212 KKPRGQRWKEPPGEEP---VRKKRGRPMTKN------LDPDPEPPSPDSPTETFAAP 259
            + RG   +  PGE P   VR++   P+T++        P P PP+ D P     AP
Sbjct: 571 PRSRGPAGRTEPGEGPQQEVRRRDQFPLTRSRAIQECRSPVP-PPAADPPEARTKAP 626



 Score = 37.4 bits (85), Expect = 0.023
 Identities = 65/291 (22%), Positives = 92/291 (31%), Gaps = 64/291 (21%)

Query: 46   QEKTPPPRPSPLEAGSDGCEEPKQQVSWEQEFLVGSSP-----GGSGRALCMVCGAEIRA 100
            Q ++P P  + L  G  G  E  Q++   ++ L+   P      G    L    G   R 
Sbjct: 2042 QRRSPSPGATRLARGGLGEGEYAQRLQALRQRLLRGGPEDGKVSGLRGPLLESLGGRARD 2101

Query: 101  PS-ADTARSHILEQHPHTLDLSPSEKSNILEAWSEGVALLQDVRAEQPSP---------- 149
            P  A  A S     H   L+    +KS+   ++S+G A  +       +P          
Sbjct: 2102 PRMARAASSEAAPHHQPPLENRGLQKSS---SFSQGEAEPRGRHRRAGAPLEIPVARLGA 2158

Query: 150  ------PNSDSGQDAHPDPDANPDAARMPAEIVVLLDSEDNPSLPKRSRPRGLRPLELPA 203
                  P+  +  +A P   A P A +              PS PK + P    P + P 
Sbjct: 2159 RRLQESPSLSALSEAQPSSPARPSAPK--------------PSTPKSAEPSATTPSDAPQ 2204

Query: 204  VPATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPSPDSPTETFAAPAEVR 263
             PA +P   K         P  EPVR  +             P  P    +T A P    
Sbjct: 2205 PPAPQPAQDK------APEPRPEPVRASK-------------PAPPPQALQTLALPLTPY 2245

Query: 264  HFTDGSFPAGFVLQLFSHTQLRGPDSKDSPKDREVAEGGLPRAESPSPAPP 314
                 S      LQL  H Q         P + +       R  SP P  P
Sbjct: 2246 AQIIQS------LQLSGHAQGPSQGPAAPPSEPKPHAAVFARVASPPPGAP 2290



 Score = 30.4 bits (67), Expect = 2.8
 Identities = 33/122 (27%), Positives = 47/122 (38%), Gaps = 24/122 (19%)

Query: 147  PSPPNSDSGQDAHPDPDANPDAARMPAEIVVLLDSEDNPSLPKRSRPRGL---RPLELPA 203
            P+PP+      + P P         P++ +  L +   P      R RGL   RP E P 
Sbjct: 2812 PTPPSVTVSPSSPPTP---------PSQALSSLKAVGPPPQTPPRRHRGLQAARPAE-PT 2861

Query: 204  VPATE--PGNKKP------RGQRWKEPPGEEPVRKKRGRPMTKNL---DPDPEPPSPDSP 252
            +P+T   P   KP             P G +PV       +  +     P PEPP+P+ P
Sbjct: 2862 LPSTHVTPSEPKPFVLDTGTPIPASTPQGVKPVSSSTPVYVVTSFVSAPPAPEPPAPEPP 2921

Query: 253  TE 254
             E
Sbjct: 2922 PE 2923



 Score = 29.3 bits (64), Expect = 6.2
 Identities = 39/138 (28%), Positives = 46/138 (33%), Gaps = 11/138 (7%)

Query: 188  PKRSRPRGLRPLELPAVPATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPP 247
            P  SRP   RP + P   A       P        P   P    +     K + P P+ P
Sbjct: 2786 PVTSRPARARPPDSPTSLAPPLAPAAPTPPSVTVSPSSPPTPPSQALSSLKAVGPPPQTP 2845

Query: 248  SPDSPTETFAAPAE----VRHFTDGSFPAGFVLQL-----FSHTQLRGPDSKDSPKDREV 298
                     A PAE      H T  S P  FVL        S  Q   P S  +P     
Sbjct: 2846 PRRHRGLQAARPAEPTLPSTHVTP-SEPKPFVLDTGTPIPASTPQGVKPVSSSTPVYVVT 2904

Query: 299  AEGGLPRA-ESPSPAPPP 315
            +    P A E P+P PPP
Sbjct: 2905 SFVSAPPAPEPPAPEPPP 2922


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 56/217 (25%), Positives = 71/217 (32%), Gaps = 26/217 (11%)

Query: 41  LRVTQQEKTPPPRPSPLEAGSDGCEEPKQQVSWEQEFLVGSSPGGSGRALCMVCGAEIRA 100
           L V   E  PPP P+P +     C+ PK     + E         S      + G     
Sbjct: 626 LEVMAIESPPPPEPTPAD-----CQSPKMTTFQDSEL--------SDELQAAMTGPAEVG 672

Query: 101 PSADTARSHILEQHPHTLDLSPSEKSNILEAWSEGVALLQDVRAEQPSPPNSDSGQ---D 157
           P+ +   SH L   P       S         S    LL D     PS P S S +   D
Sbjct: 673 PTTEKPSSH-LPPTPRATTRQDSSLGGRARHMSSSQELLGD-GPPGPSSPMSRSQEYLLD 730

Query: 158 AHPDPDANPDAAR--MPAEIVVLLDSEDNPSLPKRSRPRGLRPLELPAVPA-TEPGNKKP 214
             P P   P  AR       +        P  P++  P G      P  P  T PG+ + 
Sbjct: 731 EGPAPGTPPREARPGRHGHSIKRASVPPVPGKPRQVLPPGTSHFTPPQTPTKTRPGSPQA 790

Query: 215 RGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPSPDS 251
            G     P G  P   K  +P  + L P   P SP S
Sbjct: 791 LG----GPHGPAPATAK-VKPTPQLLPPTERPMSPRS 822



 Score = 32.3 bits (72), Expect = 0.73
 Identities = 42/176 (23%), Positives = 61/176 (34%), Gaps = 33/176 (18%)

Query: 144  AEQPSPPNSDSGQDAHPDPDANP---DAARMPAEIVVLLDSEDNPSLPKRSRPRGLRPLE 200
            +EQ  PP         P P A P   D A +P      L   +  +      P   +P+ 
Sbjct: 1183 SEQAGPPELPP-----PPPPAEPPPTDLAHLPP-----LPPPEGEARKPAKPPVSPKPVL 1232

Query: 201  LPAVPATEPGNKKPRGQRWKEP-PGEEPVRKKRGRPMTKNLDPDPEPPSPDSPTETFAAP 259
               VP  + G+  P  ++   P PG   V++  G P   +    P+PP P +  +   A 
Sbjct: 1233 TQPVPKLQ-GSPTPTSKKVPLPGPGSPEVKRAHGTPPPVS----PKPPPPPTAPKPVKAV 1287

Query: 260  AEVRHFTDGSFPAGFVLQLFSHTQLRGPDSKDSPKDREVAEGGLPRAESPSPAPPP 315
            A +   + G  PA              P     P        G P +   SPA PP
Sbjct: 1288 AGLPSGSAGPSPA--------------PSPARQPPAALAKPPGTPPSLGASPAKPP 1329


>gi|5031855 lymphocyte cytosolic protein 2 [Homo sapiens]
          Length = 533

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 61/252 (24%), Positives = 90/252 (35%), Gaps = 50/252 (19%)

Query: 34  IPRPEPMLRVTQQEKTPPPRPS----PLEAGSDGCEEPKQQVSWEQEFLVGSSPGGSGRA 89
           I RP P  +  QQ   PP RP     P  AG +    P  Q + E+       P  S   
Sbjct: 174 IDRP-PSGKTPQQPPVPPQRPMAALPPPPAGRNHSPLPPPQTNHEE-------PSRSRNH 225

Query: 90  LCMVCGAEIRAPSADTARSHILEQ-------HPHTLDLSP--SEKSNILEAWSEGVALLQ 140
                 A++ APS D +    L++        P TL   P  S+K +I    S G  L +
Sbjct: 226 KT----AKLPAPSIDRSTKPPLDRSLAPFDREPFTLGKKPPFSDKPSIPAGRSLGEHLPK 281

Query: 141 DVRAEQPSPPNSDSGQDAHPDPDANP-----------------DAARMPAEIVVLLDSED 183
             +   P PP ++  + + P P   P                 D  + P     LL    
Sbjct: 282 IQKP--PLPPTTERHERSSPLPGKKPPVPKHGWGPDRRENDEDDVHQRPLPQPALLPMSS 339

Query: 184 NPSLPKRSRPRGLRPLELPAVPA--TEPGNKKPRGQR----WKEPPGEEPVRKKRGRPMT 237
           N    + ++P  + PL    +P   +E  +  P+       + + P   P  +  GR   
Sbjct: 340 NTFPSRSTKPSPMNPLPSSHMPGAFSESNSSFPQSASLPPYFSQGPSNRPPIRAEGRNFP 399

Query: 238 KNLDPDPEPPSP 249
             L   P PPSP
Sbjct: 400 LPLPNKPRPPSP 411


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 40/173 (23%), Positives = 53/173 (30%), Gaps = 20/173 (11%)

Query: 145 EQPSPPNSDSGQDAHPDP---DANPDAARMPAEIVVLLDSEDNPSLPKRSRPRGLRPLEL 201
           ++P+P  + S      +P        A   P E       E  P+ PK   P    P   
Sbjct: 284 KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 343

Query: 202 PAVPATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPSPDSPTETFAAPAE 261
                     KKP     KEP    P   K   P T   +P P  P   +PT T +AP  
Sbjct: 344 TPKEPAPTAPKKPAPTTPKEP---APTTPKEPAPTTTK-EPSPTTPKEPAPTTTKSAPTT 399

Query: 262 VRHFTDGSFPAGFVLQLFSHTQLRGPDSKDSPKDREVAEGGLPRAESPSPAPP 314
            +       PA         T    P +   P      E      + P+P  P
Sbjct: 400 TKE------PA-------PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP 439



 Score = 29.6 bits (65), Expect = 4.7
 Identities = 49/251 (19%), Positives = 76/251 (30%), Gaps = 39/251 (15%)

Query: 145 EQPSPPNSDSGQDAHPDPDANPDAARMPAEIVVLLDSEDNPSLPKRSRPRGLRPLELPAV 204
           ++P+P          P   A P   + PA       +   P  P  + P+   P     +
Sbjct: 432 KEPAPTTPKKPAPTTPKEPA-PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 490

Query: 205 PATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEP-----PSPDSPTETFAAP 259
             T P    P       P   E +        T     +P P      +P++P E     
Sbjct: 491 TPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTT 550

Query: 260 AEVRHFTDGSFPAGFVLQLFSHTQLRG----------PDSKDSPKDREVA-----EGGLP 304
            +    T    PA    +  + T  +G          P +   P  +E+A     E    
Sbjct: 551 PKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTST 610

Query: 305 RAESPSPAPPPGLRGTLDLQVIRVRMEEPPAVSLLQDWSRHPQGTKRVGAGDTSDWPTVL 364
             + P+P  P G   T   +      +EP   +        P+GT           PT L
Sbjct: 611 TCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTT--------PKGTA----------PTTL 652

Query: 365 SESSTTVAGKP 375
            E + T   KP
Sbjct: 653 KEPAPTTPKKP 663


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 40/173 (23%), Positives = 53/173 (30%), Gaps = 20/173 (11%)

Query: 145 EQPSPPNSDSGQDAHPDP---DANPDAARMPAEIVVLLDSEDNPSLPKRSRPRGLRPLEL 201
           ++P+P  + S      +P        A   P E       E  P+ PK   P    P   
Sbjct: 325 KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPT 384

Query: 202 PAVPATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEPPSPDSPTETFAAPAE 261
                     KKP     KEP    P   K   P T   +P P  P   +PT T +AP  
Sbjct: 385 TPKEPAPTAPKKPAPTTPKEP---APTTPKEPAPTTTK-EPSPTTPKEPAPTTTKSAPTT 440

Query: 262 VRHFTDGSFPAGFVLQLFSHTQLRGPDSKDSPKDREVAEGGLPRAESPSPAPP 314
            +       PA         T    P +   P      E      + P+P  P
Sbjct: 441 TKE------PA-------PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP 480



 Score = 29.6 bits (65), Expect = 4.7
 Identities = 49/251 (19%), Positives = 76/251 (30%), Gaps = 39/251 (15%)

Query: 145 EQPSPPNSDSGQDAHPDPDANPDAARMPAEIVVLLDSEDNPSLPKRSRPRGLRPLELPAV 204
           ++P+P          P   A P   + PA       +   P  P  + P+   P     +
Sbjct: 473 KEPAPTTPKKPAPTTPKEPA-PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 531

Query: 205 PATEPGNKKPRGQRWKEPPGEEPVRKKRGRPMTKNLDPDPEP-----PSPDSPTETFAAP 259
             T P    P       P   E +        T     +P P      +P++P E     
Sbjct: 532 TPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTT 591

Query: 260 AEVRHFTDGSFPAGFVLQLFSHTQLRG----------PDSKDSPKDREVA-----EGGLP 304
            +    T    PA    +  + T  +G          P +   P  +E+A     E    
Sbjct: 592 PKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTST 651

Query: 305 RAESPSPAPPPGLRGTLDLQVIRVRMEEPPAVSLLQDWSRHPQGTKRVGAGDTSDWPTVL 364
             + P+P  P G   T   +      +EP   +        P+GT           PT L
Sbjct: 652 TCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTT--------PKGTA----------PTTL 693

Query: 365 SESSTTVAGKP 375
            E + T   KP
Sbjct: 694 KEPAPTTPKKP 704


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.131    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,782,205
Number of Sequences: 37866
Number of extensions: 1472395
Number of successful extensions: 8517
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 569
Number of HSP's that attempted gapping in prelim test: 7130
Number of HSP's gapped (non-prelim): 1899
length of query: 381
length of database: 18,247,518
effective HSP length: 104
effective length of query: 277
effective length of database: 14,309,454
effective search space: 3963718758
effective search space used: 3963718758
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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