Guide to the Human Genome
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Search of human proteins with 38679905

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38679905 tripartite motif-containing 65 [Homo sapiens]
         (517 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38679905 tripartite motif-containing 65 [Homo sapiens]            1082   0.0  
gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]    138   1e-32
gi|68160937 tripartite motif-containing 25 [Homo sapiens]             130   3e-30
gi|21630277 tripartite motif-containing 11 [Homo sapiens]             129   8e-30
gi|112421127 tripartite motif-containing 58 [Homo sapiens]            125   7e-29
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]   115   1e-25
gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]   115   1e-25
gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]    115   1e-25
gi|157743261 tripartite motif-containing 75 [Homo sapiens]            113   4e-25
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]   112   8e-25
gi|5730009 ret finger protein [Homo sapiens]                          109   5e-24
gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo s...   108   2e-23
gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa...   106   4e-23
gi|15208665 tripartite motif protein TRIM14 isoform alpha [Homo ...   103   3e-22
gi|15208663 tripartite motif protein TRIM14 isoform alpha [Homo ...   103   3e-22
gi|15208667 tripartite motif protein TRIM14 isoform alpha [Homo ...   103   3e-22
gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]    103   5e-22
gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]    103   5e-22
gi|15208660 tripartite motif protein 21 [Homo sapiens]                101   2e-21
gi|217035095 tripartite motif-containing 62 [Homo sapiens]            100   2e-21
gi|16076875 tripartite motif-containing 7 isoform 4 [Homo sapiens]    100   4e-21
gi|198442878 tripartite motif-containing 17 isoform 3 [Homo sapi...    99   1e-20
gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi...    97   4e-20
gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens]    97   5e-20
gi|37622899 ring finger protein 137 [Homo sapiens]                     94   3e-19
gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo s...    93   7e-19
gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo s...    93   7e-19
gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]    92   1e-18
gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]       91   2e-18
gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]       91   2e-18

>gi|38679905 tripartite motif-containing 65 [Homo sapiens]
          Length = 517

 Score = 1082 bits (2798), Expect = 0.0
 Identities = 517/517 (100%), Positives = 517/517 (100%)

Query: 1   MAAQLLEEKLTCAICLGLYQDPVTLPCGHNFCGACIRDWWDRCGKACPECREPFPDGAEL 60
           MAAQLLEEKLTCAICLGLYQDPVTLPCGHNFCGACIRDWWDRCGKACPECREPFPDGAEL
Sbjct: 1   MAAQLLEEKLTCAICLGLYQDPVTLPCGHNFCGACIRDWWDRCGKACPECREPFPDGAEL 60

Query: 61  RRNVALSGVLEVVRAGPARDPGPDPGPGPDPAARCPRHGRPLELFCRTEGRCVCSVCTVR 120
           RRNVALSGVLEVVRAGPARDPGPDPGPGPDPAARCPRHGRPLELFCRTEGRCVCSVCTVR
Sbjct: 61  RRNVALSGVLEVVRAGPARDPGPDPGPGPDPAARCPRHGRPLELFCRTEGRCVCSVCTVR 120

Query: 121 ECRLHERALLDAERLKREAQLRASLEVTQQQATQAEGQLLELRKQSSQIQNSACILASWV 180
           ECRLHERALLDAERLKREAQLRASLEVTQQQATQAEGQLLELRKQSSQIQNSACILASWV
Sbjct: 121 ECRLHERALLDAERLKREAQLRASLEVTQQQATQAEGQLLELRKQSSQIQNSACILASWV 180

Query: 181 SGKFSSLLQALEIQHTTALRSIEVAKTQALAQARDEEQRLRVHLEAVARHGCRIRELLEQ 240
           SGKFSSLLQALEIQHTTALRSIEVAKTQALAQARDEEQRLRVHLEAVARHGCRIRELLEQ
Sbjct: 181 SGKFSSLLQALEIQHTTALRSIEVAKTQALAQARDEEQRLRVHLEAVARHGCRIRELLEQ 240

Query: 241 VDEQTFLQESQLLQPPGPLGPLTPLQWDEDQQLGDLKQLLSRLCGLLLEEGSHPGAPAKP 300
           VDEQTFLQESQLLQPPGPLGPLTPLQWDEDQQLGDLKQLLSRLCGLLLEEGSHPGAPAKP
Sbjct: 241 VDEQTFLQESQLLQPPGPLGPLTPLQWDEDQQLGDLKQLLSRLCGLLLEEGSHPGAPAKP 300

Query: 301 VDLAPVEAPGPLAPVPSTVCPLRRKLWQNYRNLTFDPVSANRHFYLSRQDQQVKHCRQSR 360
           VDLAPVEAPGPLAPVPSTVCPLRRKLWQNYRNLTFDPVSANRHFYLSRQDQQVKHCRQSR
Sbjct: 301 VDLAPVEAPGPLAPVPSTVCPLRRKLWQNYRNLTFDPVSANRHFYLSRQDQQVKHCRQSR 360

Query: 361 GPGGPGSFELWQVQCAQSFQAGHHYWEVRASDHSVTLGVSYPQLPRCRLGPHTDNIGRGP 420
           GPGGPGSFELWQVQCAQSFQAGHHYWEVRASDHSVTLGVSYPQLPRCRLGPHTDNIGRGP
Sbjct: 361 GPGGPGSFELWQVQCAQSFQAGHHYWEVRASDHSVTLGVSYPQLPRCRLGPHTDNIGRGP 420

Query: 421 CSWGLCVQEDSLQAWHNGEAQRLPGVSGRLLGMDLDLASGCLTFYSLEPQTQPLYTFHAL 480
           CSWGLCVQEDSLQAWHNGEAQRLPGVSGRLLGMDLDLASGCLTFYSLEPQTQPLYTFHAL
Sbjct: 421 CSWGLCVQEDSLQAWHNGEAQRLPGVSGRLLGMDLDLASGCLTFYSLEPQTQPLYTFHAL 480

Query: 481 FNQPLTPVFWLLEGRTLTLCHQPGAVFPLGPQEEVLS 517
           FNQPLTPVFWLLEGRTLTLCHQPGAVFPLGPQEEVLS
Sbjct: 481 FNQPLTPVFWLLEGRTLTLCHQPGAVFPLGPQEEVLS 517


>gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]
          Length = 511

 Score =  138 bits (348), Expect = 1e-32
 Identities = 139/515 (26%), Positives = 224/515 (43%), Gaps = 70/515 (13%)

Query: 6   LEEKLTCAICLGLYQDPVTLPCGHNFCGACIRDWWDRCGKA--------------CPECR 51
           L+ + TC+ICL L+++PV++ CGH+FC ACI   W+R G                CP+CR
Sbjct: 23  LQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPCPQCR 82

Query: 52  EPFPDGAELRRNVALSGVLEVVR--AGPARDP---GPDPGPGPDPAARCPRHGRPLELFC 106
           EP    ++LR N  L+ V  ++R  + PA  P   G         AARC +HG P +L+C
Sbjct: 83  EP-ARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHGEPFKLYC 141

Query: 107 RTEGRCVCSVC-TVRECRLHERALLDAERLKREAQLRASLEVTQQQATQAEGQLLELRKQ 165
           + +GR +C VC   RE R H    LD    + +  L + L V +++    E      +K+
Sbjct: 142 QDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRSTEKKE 201

Query: 166 SSQIQNSACILASWVSGKFSSLLQALEIQHTTALRSIEVAKTQALAQARDEEQRLRVHLE 225
           S ++          V  +F +L   L  Q    L  +E    +   +  +   +L V + 
Sbjct: 202 SKELLKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQLGVEIT 261

Query: 226 AVARHGCRIRELLEQVDEQTFLQE-----SQLLQPPGPLGPLTPLQWDEDQQLGDLKQLL 280
            +++   +I+E  ++ D   FLQE     S+    PGP    T +  +   ++ ++    
Sbjct: 262 QLSKLSSQIQETAQKPD-LDFLQEFKSTLSRCSNVPGP--KPTTVSSEMKNKVWNVSLKT 318

Query: 281 SRLCGLLLEEGSHPGAPAKPVDLAPVEAPGPLAPVPSTVCPLRRKLWQNYR-NLTFDPVS 339
             L G+L +                                LR +L +  +  LT DP +
Sbjct: 319 FVLKGMLKKFKE----------------------------DLRGELEKEEKVELTLDPDT 350

Query: 340 ANRHFYLSRQDQQVKHCRQSRG-PGGPGSFEL-WQVQCAQSFQAGHHYWEVR-ASDHSVT 396
           AN    LS   + V+   +++  P  P  F+   +V  +  F +G H+WEV   S     
Sbjct: 351 ANPRLILSLDLKGVRLGERAQDLPNHPCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWA 410

Query: 397 LGVSYPQLPRCRLGPHTDNIGRGPCSWGLCVQEDSLQAWHNGEAQRLPGVSGRL--LGMD 454
            GV+   + R  L P T   G     W L  Q +  Q W     +R P   G L  + + 
Sbjct: 411 FGVARESVRRKGLTPFTPEEG----VWAL--QLNGGQYWAVTSPERSPLSCGHLSRVRVA 464

Query: 455 LDLASGCLTFYSLEPQTQPLYTFHALFNQPLTPVF 489
           LDL  G ++FY++E   + LYTF   F + + P+F
Sbjct: 465 LDLEVGAVSFYAVE-DMRHLYTFRVNFQERVFPLF 498


>gi|68160937 tripartite motif-containing 25 [Homo sapiens]
          Length = 630

 Score =  130 bits (327), Expect = 3e-30
 Identities = 145/627 (23%), Positives = 226/627 (36%), Gaps = 138/627 (22%)

Query: 6   LEEKLTCAICLGLYQDPVTLPCGHNFCGACIRDWWDRCGK--ACPECREPFPDGAELRRN 63
           L E+L+C+ICL  +++PVT PCGHNFCG+C+ + W   G    CP+CR  +    +L +N
Sbjct: 7   LAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCRAVYQARPQLHKN 66

Query: 64  VALSGVLE-VVRAGPARDPGPD--------PGPGPDPAARC------------------- 95
             L  V+E  ++A  AR+P  D          P P+    C                   
Sbjct: 67  TVLCNVVEQFLQADLAREPPADVWTPPARASAPSPNAQVACDHCLKEAAVKTCLVCMASF 126

Query: 96  -------------------------------PRHGRPLELFCRTEGRCVCSVCTVRECRL 124
                                           +H R  E FC     C+C +C V E + 
Sbjct: 127 CQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQHNRLREFFCPEHSECICHICLV-EHKT 185

Query: 125 HERALLDAERLKREAQLRASLEVTQQQATQAEGQLLELRKQSSQIQNSACILASWVSGKF 184
              A L       EA LR  L V   Q   A   L ++R +   ++ +A      +  ++
Sbjct: 186 CSPASLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQDVRMTANRKVEQLQQEY 245

Query: 185 SSLLQALEIQHTTALRSIEVAKTQALAQARDEEQRLRVHLEAVARHGCRIRELLEQVDEQ 244
           + +   L+   TT+ R I+  + +  ++     Q L      +      I + L + DE 
Sbjct: 246 TEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKEEIEQSLTKRDEF 305

Query: 245 TFLQESQLLQPPGPLGPLTP-------LQWDEDQQLGDLKQLLSRLCGLLLE-------E 290
            FL+++  L+         P       L     Q   DLK  L +  G L E        
Sbjct: 306 EFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQSTIDLKNELKQCIGRLQEPTPSSGDP 365

Query: 291 GSH-------------------------PGAPAKPVDLAPVEAPGPLAPVPST------- 318
           G H                         P  PA P  L    AP  L  +          
Sbjct: 366 GEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALPSKLPTFGAPEQLVDLKQAGLEAAAK 425

Query: 319 -------------------VCPLRRKLWQNYRNLTFDPVSANRHFYLSR--QDQQVKHCR 357
                              +   R +L + Y  +  D  +A+    LS       V    
Sbjct: 426 ATSSHPNSTSLKAKVLETFLAKSRPELLEYYIKVILDYNTAHNKVALSECYTVASVAEMP 485

Query: 358 QSRGPGGPGSFELWQVQCAQSFQAGHHYWEVRASDHSVT-LGVSYPQLPRCRLGPHTDNI 416
           Q+  P         QV     ++ G HYWEV    ++   +G+ Y  +   R GP +  +
Sbjct: 486 QNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGVGICYGSMN--RQGPES-RL 542

Query: 417 GRGPCSWGLCVQ--EDSLQAWHNGEAQRLPGVSGRLLGMDLDLASGCLTFYSLEPQTQPL 474
           GR   SW  CV+     + AWHN   + LP      +G+ L+   G + F+++  +   +
Sbjct: 543 GRNSASW--CVEWFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVADKVHLM 600

Query: 475 YTFHALFNQPLTPVFWLLE-GRTLTLC 500
           Y F   F + L P FW+   G TL++C
Sbjct: 601 YKFRVDFTEALYPAFWVFSAGATLSIC 627


>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
          Length = 468

 Score =  129 bits (323), Expect = 8e-30
 Identities = 156/522 (29%), Positives = 221/522 (42%), Gaps = 95/522 (18%)

Query: 6   LEEKLTCAICLGLYQDPVTLPCGHNFCGACIRDWWDR--CGKACPECREPFPDGAELRRN 63
           L+E+ TCAICL  + DPV   CGHNFC  CIR  W +     ACPECRE  P    LR N
Sbjct: 10  LQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQPEGPYACPECRELSPQ-RNLRPN 68

Query: 64  VALSGVLEVVRAGPARDPGPDPGPGPDPAARCPRHGRPLELFCRTEGRCVCSVC--TVRE 121
             L+ + E+     AR   P   P P P   CP H  PL  FC  E R +C+ C  +   
Sbjct: 69  RPLAKMAEM-----ARRLHP---PSPVPQGVCPAHREPLAAFCGDELRLLCAACERSGEH 120

Query: 122 CRLHERALLD-AERLKREAQLRASLEVTQQQATQA--------EGQLLELRKQSSQIQNS 172
                R L D AE LK  A+L  SLE  ++Q   A        E  +L  +   SQ QN 
Sbjct: 121 WAHRVRPLQDAAEDLK--AKLEKSLEHLRKQMQDALLFQAQADETCVLWQKMVESQRQN- 177

Query: 173 ACILASWVSGKFSSLLQALEIQHTTALRSIEVAKTQALAQARDEEQRLRVHLEAVARHGC 232
                  V G+F  L + L  +    L+ +E  + + L        RLR     + +   
Sbjct: 178 -------VLGEFERLRRLLAEEEQQLLQRLEEEELEVL-------PRLREGAAHLGQQSA 223

Query: 233 RIRELLEQVDEQTFLQESQLLQPPGPLGPLTPLQWDEDQQLGDLKQLLSRLCGLLLEEGS 292
            + EL+ +++ +  L    LLQ                    D+K  L R+  + L+   
Sbjct: 224 HLAELIAELEGRCQLPALGLLQ--------------------DIKDALRRVQDVKLQ--- 260

Query: 293 HPGAPAKPVDLAPVEAPGPLAPVPSTVCPLRRKLWQNYR-NLTFDPVSANRHFYLSRQDQ 351
                  P ++ P+E    +  VP  V  LRR     +R ++T DP +AN    LS   +
Sbjct: 261 -------PPEVVPMEL-RTVCRVPGLVETLRR-----FRGDVTLDPDTANPELILSEDRR 307

Query: 352 QVKH--CRQSRGPGGPGSFELWQVQCAQS-FQAGHHYWEVRASDH-SVTLGVSYPQLPRC 407
            V+    RQ+  P  P  F+       Q  F +G HYWEV   D  S  LGV    + R 
Sbjct: 308 SVQRGDLRQAL-PDSPERFDPGPCVLGQERFTSGRHYWEVEVGDRTSWALGVCRENVNRK 366

Query: 408 RLGPHTDNIGRGPCSWGLCVQEDSLQAWHNGEAQRLPGVSG--RLLGMDLDLASGCLTFY 465
             G     +  G   W L      L +++N   + L  +    R +G+ LD  +G L+FY
Sbjct: 367 EKG----ELSAGNGFWILVF----LGSYYNSSERALAPLRDPPRRVGIFLDYEAGHLSFY 418

Query: 466 SLEPQTQPLYTFHAL-FNQPLTPVFWLLEG--RTLTLCHQPG 504
           S    +  L+ F  + F+  L P+F  L      +T+C   G
Sbjct: 419 SATDGSL-LFIFPEIPFSGTLRPLFSPLSSSPTPMTICRPKG 459


>gi|112421127 tripartite motif-containing 58 [Homo sapiens]
          Length = 486

 Score =  125 bits (315), Expect = 7e-29
 Identities = 134/507 (26%), Positives = 218/507 (42%), Gaps = 71/507 (14%)

Query: 6   LEEKLTCAICLGLYQDPVTLPCGHNFCGACIRDWWDRCG------KACPECREPF-PDGA 58
           L E   C +CL   Q+PV++ CGH+FC  CI ++ ++         ACP+CR PF P G 
Sbjct: 10  LREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQGGVYACPQCRGPFRPSG- 68

Query: 59  ELRRNVALSGVLEVVRAGPARDPGPDPGPGPDPAARCPRHGRPLELFCRTEGRCVCSVCT 118
             R N  L+G++E VR       G   GPG   A RC RHG  L  FC  +   +C VC 
Sbjct: 69  -FRPNRQLAGLVESVRR-----LGLGAGPG---ARRCARHGEDLSRFCEEDEAALCWVCD 119

Query: 119 V-RECRLHERALLDAERLKREAQLRASLEVTQQQATQAEGQLLELRKQSSQIQNSACILA 177
              E R H  A L       + +L+ +LE+ +++   A  Q   + K++   +    +  
Sbjct: 120 AGPEHRTHRTAPLQEAAGSYQVKLQMALELMRKELEDALTQEANVGKKTVIWKEKVEMQR 179

Query: 178 SWVSGKFSSLLQALEIQHTTALRSIEVAKTQALAQARDEEQRLRVHLEAVARHGCRIREL 237
                +F      L  +    LR +E  +   L + R+ + RL    +A       ++EL
Sbjct: 180 QRFRLEFEKHRGFLAQEEQRQLRRLEAEERATLQRLRESKSRLVQQSKA-------LKEL 232

Query: 238 LEQVDEQTFLQESQLLQPPGPLGPLTPLQWDEDQQLGDLKQLLSRLCGLLLEEGSHPGAP 297
            +++ E+         Q P  LG                  LL  + G+L    +     
Sbjct: 233 ADELQER--------CQRPA-LG------------------LLEGVRGVLSRSKAVTRLE 265

Query: 298 AKPVDLAPVEAPGPLAPVPSTVCPLRRKLWQNYR-NLTFDPVSANRHFYLSRQDQQVKHC 356
           A+ +         P+    +   P RR+L + ++ ++  DP +A+    L+   + V+  
Sbjct: 266 AENI---------PMELKTACCIPGRRELLRKFQVDVKLDPATAHPSLLLTADLRSVQDG 316

Query: 357 RQSRG-PGGPGSFELWQ-VQCAQSFQAGHHYWEVRASDHSV-TLGVSYPQLPRCRLGPHT 413
              R  P  P  F+ W  +   QSF +G HYWEV   + +   LGV    LP  R G  T
Sbjct: 317 EPWRDVPNNPERFDTWPCILGLQSFSSGRHYWEVLVGEGAEWGLGVCQDTLP--RKGETT 374

Query: 414 DNIGRGPCSWGL-CVQEDSLQAWHNGEAQRLPGVSGRLLGMDLDLASGCLTFYSLEPQTQ 472
            +   G   W L  ++ +      +     L   S R +G+ LD  +G ++FY++   + 
Sbjct: 375 PSPENG--VWALWLLKGNEYMVLASPSVPLLQLESPRCIGIFLDYEAGEISFYNVTDGSY 432

Query: 473 PLYTFHALFNQPLTPVFWLLEGRTLTL 499
            +YTF+ LF+  L P F++ +   L L
Sbjct: 433 -IYTFNQLFSGLLRPYFFICDATPLIL 458


>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
          Length = 518

 Score =  115 bits (288), Expect = 1e-25
 Identities = 124/508 (24%), Positives = 205/508 (40%), Gaps = 49/508 (9%)

Query: 2   AAQLLEEKLTCAICLGLYQDPVTLPCGHNFCGACIRDWWDRCGK--ACPECREPFPDGAE 59
           A + L+ + +C++CL   ++PV + CGHNFC ACI  WW+   +   CP CR+       
Sbjct: 19  ALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKT-SRYRS 77

Query: 60  LRRNVALSGVLEVVRAGPA-----RDPGPDPGPGPDPAARCPRHGRPLELFCRTEGRCVC 114
           LR N  L  ++E+ +   A     RD            + CP+H   L LFC  +   VC
Sbjct: 78  LRPNRQLGSMVEIAKQLQAVKRKIRD-----------ESLCPQHHEALSLFCYEDQEAVC 126

Query: 115 SVCTVREC-RLHERALLDAERLKREAQLRASLEVTQQQATQAEGQLLELRKQSSQIQNSA 173
            +C +    R H    LD    + + +L+  LE  +Q+  +         K+  +++   
Sbjct: 127 LICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKRLV 186

Query: 174 CILASWVSGKFSSLLQALEIQHTTALRSIEVAKTQALAQARD------EEQRLRVHLEAV 227
                 +  +F  L + L+ +    L  +E  +   L + R+      +++R   HL A 
Sbjct: 187 ESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLAAE 246

Query: 228 ARHGCRIRELLEQVDEQTFLQESQLLQPPGPLGPLTPLQWDEDQQLGDLKQLLSRLCGLL 287
               C         D ++ L+++   +  G L  + P          D K LL    GL+
Sbjct: 247 VEGKCLQSGFEMLKDVKSTLEKNIPRKFGGSLSTICP---------RDHKALL----GLV 293

Query: 288 LEEGSHPGAPAKPVDLAPVEAPGPLAPVPSTVCPLRRKLWQNYRNLTFDPVSANRHFYLS 347
            E           V    +E     +  P     LR+ L Q   ++T DP +A+ +  LS
Sbjct: 294 KEINRCEKVKTMEVTSVSIELEKNFSNFPRQYFALRKILKQLIADVTLDPETAHPNLVLS 353

Query: 348 RQDQQVK--HCRQSRGPGGPGSFELWQ-VQCAQSFQAGHHYWEVRASDHS-VTLGVSYPQ 403
              + VK    R    P  P  F  +  V   + F +G HYWEV   D +   +GV    
Sbjct: 354 EDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCRDS 413

Query: 404 LPR-CRLGPHTDNIGRGPCSWGLCVQEDSLQAWHNGEAQRLPGVSGRLLGMDLDLASGCL 462
           + R   L P  +        W      D   A           V  + +G+ LD  +G L
Sbjct: 414 VSRKGELTPLPETGYWRVRLW----NGDKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTL 469

Query: 463 TFYSLEPQTQPLYTFHALFNQPLTPVFW 490
           +FY++  ++  +YTF   F + L P+F+
Sbjct: 470 SFYNVTDRSH-IYTFTDTFTEKLWPLFY 496


>gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  115 bits (287), Expect = 1e-25
 Identities = 145/518 (27%), Positives = 219/518 (42%), Gaps = 95/518 (18%)

Query: 3   AQLLEEKLTCAICLGLYQDPVTLPCGHNFCGACIRDWWDRC-GK----------ACPECR 51
           A+ L+E+ TC+ICL  + DPV   CGHNFC ACI+  W++  GK           CPECR
Sbjct: 7   ARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECR 66

Query: 52  EPFPDGAELRRNVALSGVLEVVRAGPARDPGPDPGPGPDPAARCPRHGRPLELFCRTEGR 111
           E  P    L  N  L+ V E+ +            PG      C  H  PL+LFC+ +  
Sbjct: 67  EMSPQ-RNLLPNRLLTKVAEMAQ----------QHPGLQKQDLCQEHHEPLKLFCQKDQS 115

Query: 112 CVCSVC-TVRECRLHERALLDAERLKR--EAQLRASLEVTQQQATQAEGQLLELRKQSSQ 168
            +C VC   RE RLH   +L AE   +  + +L   +E  ++Q T+  G L    +QS  
Sbjct: 116 PICVVCRESREHRLHR--VLPAEEAVQGYKLKLEEDMEYLREQITRT-GNLQAREEQS-- 170

Query: 169 IQNSACILASWVSGKFSSLLQALEIQHTTALRSIEVAKTQALAQARDEEQ-----RLRVH 223
                  LA W  GK     + + ++    +    V + Q L QA + E+     RLR  
Sbjct: 171 -------LAEW-QGKVKERRERIVLEF-EKMNLYLVEEEQRLLQALETEEEETASRLRES 221

Query: 224 LEAVARHGCRIRELLEQVDEQTFLQESQLLQPPGPLGPLTPLQWDEDQQLGDLKQLLSRL 283
           +  + R G  +  LL Q++E++           GPL           Q L D+K+ LSR 
Sbjct: 222 VACLDRQGHSLELLLLQLEERS---------TQGPL-----------QMLQDMKEPLSRK 261

Query: 284 CGLLLEEGSHPGAPAKPVDLAPVEAPGPLAPVPSTVCPLRRKLWQNYRNLTFDPVSANRH 343
             + ++       P    ++AP   P  +  VP  +  LR  L     ++  D  SA  +
Sbjct: 262 NNVSVQ------CP----EVAPPTRPRTVCRVPGQIEVLRGFL----EDVVPDATSAYPY 307

Query: 344 --FYLSRQDQQVKHCRQSRGPGGPGSFELWQVQCAQ-SFQAGHHYWEVR---ASDHSVTL 397
              Y SRQ + +    +  G      F  +     Q +F +G HYWEV      D    L
Sbjct: 308 LLLYESRQRRYLGSSPEGSGFCSKDRFVAYPCAVGQTAFSSGRHYWEVGMNITGDALWAL 367

Query: 398 GVSYPQLPRCRLGPHTDNIGRGPCSWGLCVQEDSLQAWHNGEAQRLPGV---SGRLLGMD 454
           GV    + R       D + + P +    VQ      + +  +   P +       +G+ 
Sbjct: 368 GVCRDNVSR------KDRVPKCPENGFWVVQLSKGTKYLSTFSALTPVMLMEPPSHMGIF 421

Query: 455 LDLASGCLTFYSLEPQTQPLYTF-HALFNQPLTPVFWL 491
           LD  +G ++FYS+   +  L+T+  A F  PL P F L
Sbjct: 422 LDFEAGEVSFYSVSDGSH-LHTYSQATFPGPLQPFFCL 458


>gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  115 bits (287), Expect = 1e-25
 Identities = 145/518 (27%), Positives = 219/518 (42%), Gaps = 95/518 (18%)

Query: 3   AQLLEEKLTCAICLGLYQDPVTLPCGHNFCGACIRDWWDRC-GK----------ACPECR 51
           A+ L+E+ TC+ICL  + DPV   CGHNFC ACI+  W++  GK           CPECR
Sbjct: 7   ARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECR 66

Query: 52  EPFPDGAELRRNVALSGVLEVVRAGPARDPGPDPGPGPDPAARCPRHGRPLELFCRTEGR 111
           E  P    L  N  L+ V E+ +            PG      C  H  PL+LFC+ +  
Sbjct: 67  EMSPQ-RNLLPNRLLTKVAEMAQ----------QHPGLQKQDLCQEHHEPLKLFCQKDQS 115

Query: 112 CVCSVC-TVRECRLHERALLDAERLKR--EAQLRASLEVTQQQATQAEGQLLELRKQSSQ 168
            +C VC   RE RLH   +L AE   +  + +L   +E  ++Q T+  G L    +QS  
Sbjct: 116 PICVVCRESREHRLHR--VLPAEEAVQGYKLKLEEDMEYLREQITRT-GNLQAREEQS-- 170

Query: 169 IQNSACILASWVSGKFSSLLQALEIQHTTALRSIEVAKTQALAQARDEEQ-----RLRVH 223
                  LA W  GK     + + ++    +    V + Q L QA + E+     RLR  
Sbjct: 171 -------LAEW-QGKVKERRERIVLEF-EKMNLYLVEEEQRLLQALETEEEETASRLRES 221

Query: 224 LEAVARHGCRIRELLEQVDEQTFLQESQLLQPPGPLGPLTPLQWDEDQQLGDLKQLLSRL 283
           +  + R G  +  LL Q++E++           GPL           Q L D+K+ LSR 
Sbjct: 222 VACLDRQGHSLELLLLQLEERS---------TQGPL-----------QMLQDMKEPLSRK 261

Query: 284 CGLLLEEGSHPGAPAKPVDLAPVEAPGPLAPVPSTVCPLRRKLWQNYRNLTFDPVSANRH 343
             + ++       P    ++AP   P  +  VP  +  LR  L     ++  D  SA  +
Sbjct: 262 NNVSVQ------CP----EVAPPTRPRTVCRVPGQIEVLRGFL----EDVVPDATSAYPY 307

Query: 344 --FYLSRQDQQVKHCRQSRGPGGPGSFELWQVQCAQ-SFQAGHHYWEVR---ASDHSVTL 397
              Y SRQ + +    +  G      F  +     Q +F +G HYWEV      D    L
Sbjct: 308 LLLYESRQRRYLGSSPEGSGFCSKDRFVAYPCAVGQTAFSSGRHYWEVGMNITGDALWAL 367

Query: 398 GVSYPQLPRCRLGPHTDNIGRGPCSWGLCVQEDSLQAWHNGEAQRLPGV---SGRLLGMD 454
           GV    + R       D + + P +    VQ      + +  +   P +       +G+ 
Sbjct: 368 GVCRDNVSR------KDRVPKCPENGFWVVQLSKGTKYLSTFSALTPVMLMEPPSHMGIF 421

Query: 455 LDLASGCLTFYSLEPQTQPLYTF-HALFNQPLTPVFWL 491
           LD  +G ++FYS+   +  L+T+  A F  PL P F L
Sbjct: 422 LDFEAGEVSFYSVSDGSH-LHTYSQATFPGPLQPFFCL 458


>gi|157743261 tripartite motif-containing 75 [Homo sapiens]
          Length = 468

 Score =  113 bits (283), Expect = 4e-25
 Identities = 107/502 (21%), Positives = 209/502 (41%), Gaps = 56/502 (11%)

Query: 6   LEEKLTCAICLGLYQDPVTLPCGHNFCGACIRDWWDRCGK--ACPECREPFPDGAELRRN 63
           L+ +  C+ICL    DPVT+ CGHNFC +CI+  W    +   CP CR    +G   R N
Sbjct: 10  LQAEAKCSICLDYLSDPVTIECGHNFCRSCIQQSWLDLQELFPCPVCRHQCQEG-HFRSN 68

Query: 64  VALSGVLEVVRAGPARDPGPDPGPGPDPAARCPRHGRPLELFCRTEGRCVCSVCT-VREC 122
             L  ++E+ +   +           +    C +H +PL +FC+ +   +C +CT   + 
Sbjct: 69  TQLGRMIEIAKLLQSTKSNKRK---QEETTLCEKHNQPLSVFCKEDLMVLCPLCTQPPDH 125

Query: 123 RLHERALLDAERLKREAQLRASLEVTQQQATQAEGQLLELRKQSSQIQNSACILASWVSG 182
           + H    ++   +    +  + ++  ++Q    +  +    K+  +++         +S 
Sbjct: 126 QGHHVRPIEKAAIHYRKRFCSYIQPLKKQLADLQKLISTQSKKPLELREMVENQRQELSS 185

Query: 183 KFSSLLQALEIQHTTALRSIEVAKTQALAQARDEEQRLRVHLEAVARHGCRIRELLEQVD 242
           +F  L Q L+       R  +   ++   + +D +Q+L  ++ A + +   ++  L +V 
Sbjct: 186 EFEHLNQFLD-------REQQAVLSRLAEEEKDNQQKLSANITAFSNYSATLKSQLSKVV 238

Query: 243 EQTFLQESQLLQPPGPLGPLTPLQWDEDQQLGDLKQLLSRLCGLLLEEGSHPGAPAKPVD 302
           E + L E +L                    L  +K         +  E  +  +P+    
Sbjct: 239 ELSELSELEL--------------------LSQIK---------IFYESENESSPS---- 265

Query: 303 LAPVEAPGPLAPVPSTVCPLRRKLWQNYRNLTFDPVSANRHFYLSRQDQQVKHC-RQSRG 361
           +  +         P     L+R + +    +  DP +A+ +  +S   ++V+   R+ + 
Sbjct: 266 IFSIHLKRDGCSFPPQYSALQRIIKKFKVEIILDPETAHPNLIVSEDKKRVRFTKRKQKV 325

Query: 362 PGGPGSFELWQVQCA-QSFQAGHHYWEVRASDHSV-TLGVSYPQLPRCRLGPHTDNIGRG 419
           PG P  F +  V      F +G H+WE+   D S   +G+    LP     P +    + 
Sbjct: 326 PGFPKRFTVKPVVLGFPYFHSGRHFWEIEVGDKSEWAIGICKDSLPTKARRPSS---AQQ 382

Query: 420 PCSWGLCVQEDSLQAWHNGEAQRLPGVSGRLLGMDLDLASGCLTFYSLEPQTQPLYTFHA 479
            C W + +Q+D   A        L  V  R +G+ LD   G ++FY++  ++  + TF  
Sbjct: 383 EC-WRIELQDDGYHAPGAFPTPLLLEVKARAIGIFLDYEMGEISFYNMAEKSH-ICTFTD 440

Query: 480 LFNQPLTPVFWL-LEGRTLTLC 500
            F  PL P F++  + + L +C
Sbjct: 441 TFTGPLRPYFYVGPDSQPLRIC 462


>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
          Length = 488

 Score =  112 bits (280), Expect = 8e-25
 Identities = 127/503 (25%), Positives = 203/503 (40%), Gaps = 69/503 (13%)

Query: 2   AAQLLEEKLTCAICLGLYQDPVTLPCGHNFCGACIRDWWDRCGK--ACPECREPFPDGAE 59
           A + L+ + +C++CL   ++PV + CGHNFC ACI  WW+   +   CP CR+       
Sbjct: 19  ALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWEDLERDFPCPVCRKT-SRYRS 77

Query: 60  LRRNVALSGVLEVVRAGPA-----RDPGPDPGPGPDPAARCPRHGRPLELFCRTEGRCVC 114
           LR N  L  ++E+ +   A     RD            + CP+H   L LFC  +   VC
Sbjct: 78  LRPNRQLGSMVEIAKQLQAVKRKIRD-----------ESLCPQHHEALSLFCYEDQEAVC 126

Query: 115 SVCTVREC-RLHERALLDAERLKREAQLRASLEVTQQQATQAEGQLLELRKQSSQIQNSA 173
            +C +    R H    LD    + + +L+  LE  +Q       +L E+ +  S  +   
Sbjct: 127 LICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQ-------KLQEITRCKSSEEKKP 179

Query: 174 CILASWVSGKFSSLLQALEIQHTTALRSIEVAKTQALAQARDEEQRLRVHLEAVARH-GC 232
             L   V  +   +L+  E  H    R ++  +   L++  +EEQ +   L   A H G 
Sbjct: 180 GELKRLVESRRQQILREFEELH----RRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGD 235

Query: 233 RIRELLEQVDEQTFLQESQLLQPPGPLGPLTPLQWDEDQQLGDLKQLLSRLCGLLLEEGS 292
           + R+L     E     E + LQ                + L D+K  L +   +   E  
Sbjct: 236 KRRDLAHLAAE----VEGKCLQ-------------SGFEMLKDVKSTLEKCEKVKTME-- 276

Query: 293 HPGAPAKPVDLAPVEAPGPLAPVPSTVCPLRRKLWQNYRNLTFDPVSANRHFYLSRQDQQ 352
                   V    +E     +  P     LR+ L Q   ++T DP +A+ +  LS   + 
Sbjct: 277 --------VTSVSIELEKNFSNFPRQYFALRKILKQLIADVTLDPETAHPNLVLSEDRKS 328

Query: 353 VK--HCRQSRGPGGPGSFELWQ-VQCAQSFQAGHHYWEVRASDHS-VTLGVSYPQLPR-C 407
           VK    R    P  P  F  +  V   + F +G HYWEV   D +   +GV    + R  
Sbjct: 329 VKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCRDSVSRKG 388

Query: 408 RLGPHTDNIGRGPCSWGLCVQEDSLQAWHNGEAQRLPGVSGRLLGMDLDLASGCLTFYSL 467
            L P  +        W      D   A           V  + +G+ LD  +G L+FY++
Sbjct: 389 ELTPLPETGYWRVRLW----NGDKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNV 444

Query: 468 EPQTQPLYTFHALFNQPLTPVFW 490
             ++  +YTF   F + L P+F+
Sbjct: 445 TDRSH-IYTFTDTFTEKLWPLFY 466


>gi|5730009 ret finger protein [Homo sapiens]
          Length = 513

 Score =  109 bits (273), Expect = 5e-24
 Identities = 136/527 (25%), Positives = 212/527 (40%), Gaps = 95/527 (18%)

Query: 3   AQLLEEKLTCAICLGLYQDPVTLPCGHNFCGACIRDWWD--RCGKACPECREPFPDGAEL 60
           A+ L+++ TC +CL  + +P+ L CGHN C AC+   W       +CP+CRE FP    +
Sbjct: 7   AECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTAETNVSCPQCRETFPQ-RHM 65

Query: 61  RRNVALSGVLEVVRAGPARDPGPDPGPGPDPAARCPRHGRPLELFCRTEGRCVCSVC-TV 119
           R N  L+ V ++V+      P    GPG +    C +H  PL+L+C  +   +C VC   
Sbjct: 66  RPNRHLANVTQLVKQLRTERPS---GPGGEMGV-CEKHREPLKLYCEEDQMPICVVCDRS 121

Query: 120 RECRLH-------------ERALLDAERLKREAQLRASLEVTQQQATQAEGQLLELRKQS 166
           RE R H             E+     + LKR   L+   +  + Q  QA  +LL L    
Sbjct: 122 REHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLK---KRRRAQGEQARAELLSL---- 174

Query: 167 SQIQNSACILASWVSGKFSSLLQALEIQHTTALRSIEVAKTQALAQARDEEQRLRVHLE- 225
           +Q++    +   W   +F  L  +L+ +H   L             AR EE  L ++   
Sbjct: 175 TQMEREKIV---W---EFEQLYHSLK-EHEYRL------------LARLEELDLAIYNSI 215

Query: 226 --AVARHGCRI---RELLEQVDEQTFLQESQLLQPPGPLGPLT-----PLQWDEDQQLGD 275
             A+ +  C I     L+ Q++E+      +LLQ  G           P  W     L +
Sbjct: 216 NGAITQFSCNISHLSSLIAQLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQE 275

Query: 276 LKQLLSRLCGLLLEEGSHPGAPAKPVDLAPVEAPGPLAPVPSTVCPLRRKLWQNYRNLTF 335
              + ++ C L L E           D+  ++                R+      ++T 
Sbjct: 276 KIHIFAQKC-LFLTESLKQFTEKMQSDMEKIQE--------------LREAQLYSVDVTL 320

Query: 336 DPVSANRHFYLSRQDQQVKHC-RQSRGPGGPGSFELWQ-VQCAQSFQAGHHYWEVRASDH 393
           DP +A     LS   +QV++   Q   P  P  F L+  V  +  F AG HYWEV   D 
Sbjct: 321 DPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERFNLFPCVLGSPCFIAGRHYWEVEVGDK 380

Query: 394 SV-TLGVSYPQLPRCRLGPHTDNIGRGPCSWGLCVQEDSLQAWHNGEAQRLPGVSGRL-- 450
           +  T+GV    +  CR G  T     G   W       ++  W+  E   L      L  
Sbjct: 381 AKWTIGVCEDSV--CRKGGVTSAPQNG--FW-------AVSLWYGKEYWALTSPMTALPL 429

Query: 451 ------LGMDLDLASGCLTFYSLEPQTQPLYTFHALFNQPLTPVFWL 491
                 +G+ LD  +G ++FY++  +       HA F  P+ P F L
Sbjct: 430 RTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYFSL 476


>gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo
           sapiens]
          Length = 500

 Score =  108 bits (269), Expect = 2e-23
 Identities = 138/538 (25%), Positives = 215/538 (39%), Gaps = 100/538 (18%)

Query: 1   MAAQLLEEKLTCAICLGLYQDPVTLPCGHNFCGACIRDWWDRCGK--ACPECREPFPDGA 58
           M A+ ++E+LTC ICL  +QDPV++ CGHNFC  C+   W   G    CPECR P    A
Sbjct: 1   MEAEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAA 60

Query: 59  ELRRNVALSGVLEVVRAGPARDPGPDPGPGPDPAARCPRHGRPLELFCRTEGRCVCSVC- 117
            LR N AL+ + E  +             GP P   C RH  PL LFC  + R VC VC 
Sbjct: 61  -LRPNWALARLTEKTQRRRL---------GPVPPGLCGRHWEPLRLFCEDDQRPVCLVCR 110

Query: 118 TVRECRLHERALLDAERLKREAQLRASLEVTQQQATQAEGQLLELRKQSSQIQNSACILA 177
             +E + H  A +D E  +        + V + +       L   +++   +++   ++A
Sbjct: 111 ESQEHQTHAMAPID-EAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVA 169

Query: 178 SWVSGKFSSLLQALEIQHTTALRSIEVAKTQALAQARDEEQRLRVHLEAVARHGCRIREL 237
                K    LQ +E+++ T  +             + + QR+R+  E    H   + E 
Sbjct: 170 KM---KKVMHLQDVEVKNATQWKD------------KIKSQRMRISTEFSKLHNFLVEE- 213

Query: 238 LEQVDEQTFLQESQLLQPPGPLGPLTPLQWDEDQQLGD----LKQLLSRLCGLLLEEGSH 293
                E  FLQ             L   + +  ++L +    L Q ++ L  L+LE G  
Sbjct: 214 -----EDLFLQR------------LNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEK 256

Query: 294 PGAPAKPVDLAPVEA----------PGPLAPVPSTVC--PLRRKLWQNYR---NLTFDPV 338
             AP   +   P E               A    TVC  PL +++ + ++   NL  D  
Sbjct: 257 SQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKVKTVCQIPLMKEMLKRFQVAVNLAED-- 314

Query: 339 SANRHFYLSRQDQQVKHCRQS----------------RGPGGPGSFELWQ----VQCAQS 378
           +A+     S++ + VK+   +                R P      E +Q    V     
Sbjct: 315 TAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNV 374

Query: 379 FQAGHHYWEVRASDH-SVTLGVSYPQL----PRCRLGPHTDNIGRGPCSWGLCVQEDSLQ 433
           F +G HYWEV + D   V +GV    +     R ++ P   ++G     W        L 
Sbjct: 375 FTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSP---DVGIWAIYWS-AAGYWPLI 430

Query: 434 AWHNGEAQRLPGVSGRLLGMDLDLASGCLTFYSLEPQTQPLYTFHALFNQPLTPVFWL 491
            +     Q+ P +    +G+ LD  +G ++FYS       L+TF       L P FWL
Sbjct: 431 GFPGTPTQQEPAL--HRVGVYLDRGTGNVSFYSAVDGVH-LHTFSCSSVSRLRPFFWL 485


>gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo
           sapiens]
          Length = 474

 Score =  106 bits (265), Expect = 4e-23
 Identities = 134/503 (26%), Positives = 215/503 (42%), Gaps = 56/503 (11%)

Query: 1   MAAQLLEEKLTCAICLGLYQDPVTLPCGHNFCGACIRDWWDRCGK--ACPECREPFPDGA 58
           M A+ ++E+LTC ICL  +QDPV++ CGHNFC  C+   W   G    CPECR P    A
Sbjct: 1   MEAEDIQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGPFPCPECRHPSAPAA 60

Query: 59  ELRRNVALSGVLEVVRAGPARDPGPDPGPGPDPAARCPRHGRPLELFCRTEGRCVCSVC- 117
            LR N AL+ + E  +             GP P   C RH  PL LFC  + R VC VC 
Sbjct: 61  -LRPNWALARLTEKTQRRRL---------GPVPPGLCGRHWEPLRLFCEDDQRPVCLVCR 110

Query: 118 TVRECRLHERALLD-AERLKREAQLRASLEVTQQQATQAEGQLLELRKQSSQIQNSACIL 176
             +E + H  A +D A    RE  L++   +  +       Q +E+ K ++Q ++     
Sbjct: 111 ESQEHQTHAMAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEV-KNATQWKDKIKSQ 169

Query: 177 ASWVSGKFSSLLQALEIQHTTALRSIEVAKTQALAQARDEEQRLRVHLEAVARHGCRIRE 236
              +S +FS L   L  +    L+ +   + +   +  +   +L   + +       +++
Sbjct: 170 RMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIAS-------LKK 222

Query: 237 LLEQVDEQTFLQESQLLQPPGPLGPLTPLQWDEDQQLGDLKQLLSRLCGL-LLEEGSHPG 295
           L+ +V E++     +LLQ P  +   + +Q D +  L  +K  +  +C + L++E     
Sbjct: 223 LILEVGEKSQAPTLELLQNPKEVLTRSEIQ-DVNYSLEAVK--VKTVCQIPLMKEMLKRF 279

Query: 296 APAKPVDLAPVEAPGPLAPVPSTVCPLRRKLWQNYRNLTFDPV--SANRHFYLSRQDQQV 353
             A  V+LA   A       P  V     +  +N  + +  PV  SA  +F   R  Q+ 
Sbjct: 280 QVA--VNLAEDTAH------PKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKT 331

Query: 354 KHCRQSRGPGGPGSFELWQVQCAQSFQAGHHYWEVRASDH-SVTLGVSYPQL----PRCR 408
               + +         L  V     F +G HYWEV + D   V +GV    +     R +
Sbjct: 332 AFVERFQ--------HLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSK 383

Query: 409 LGPHTDNIGRGPCSWGLCVQEDSLQAWHNGEAQRLPGVSGRLLGMDLDLASGCLTFYSLE 468
           + P   ++G     W        L  +     Q+ P +    +G+ LD  +G ++FYS  
Sbjct: 384 MSP---DVGIWAIYWS-AAGYWPLIGFPGTPTQQEPAL--HRVGVYLDRGTGNVSFYSAV 437

Query: 469 PQTQPLYTFHALFNQPLTPVFWL 491
                L+TF       L P FWL
Sbjct: 438 DGVH-LHTFSCSSVSRLRPFFWL 459


>gi|15208665 tripartite motif protein TRIM14 isoform alpha [Homo
           sapiens]
          Length = 442

 Score =  103 bits (258), Expect = 3e-22
 Identities = 113/423 (26%), Positives = 177/423 (41%), Gaps = 33/423 (7%)

Query: 94  RCPRHG-RPLELFCRTEGRCVCSVCTVRECR------LHERALLDAERLKREAQLRASLE 146
           RCP HG R  ELFCR   RCVC++C V          L   A +  ++L +E   +  L 
Sbjct: 23  RCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLSQECLKQ--LA 80

Query: 147 VTQQQATQAEGQLLELRKQSSQIQNSACILASWVSGKFSSLLQALEIQHTTALRSIEVAK 206
           + +QQ       + ++   + +++ +A    +W+ GKF+ L   L+ +   A + I+   
Sbjct: 81  IKKQQHID---NITQIEDATEKLKANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNT 137

Query: 207 TQALAQARDEEQRLRVHLEAVARHGCRIRELLEQVDE----QTFLQESQLLQPPGPLGPL 262
              L   R++    R  L+ +     R+  + ++ D     Q +    Q +Q    LG L
Sbjct: 138 QLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATEQEMQQQMSLGEL 197

Query: 263 ---TPLQWDEDQQLGDLKQLLSRLCGLLLEEGSHPGAPAKPVDLAPVEAPGPLAPVPSTV 319
               PL ++  +     K L+  +   L          +    L+   +  P   + ++ 
Sbjct: 198 CHPVPLSFEPVKSF--FKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTKPGTLLKTSP 255

Query: 320 CPLRRKLWQNYRNLTFDPVSANRHFYLSRQDQQVKHCRQ--SRGPGGPGSFE-LWQVQCA 376
            P R  L +  R  T DP + +    LS  D+    C    S GP     F+ LWQV   
Sbjct: 256 SPERSLLLKYARTPTLDPDTMHARLRLSA-DRLTVRCGLLGSLGPVPVLRFDALWQVLAR 314

Query: 377 QSFQAGHHYWEVRASDHSVT--LGVSYPQLPRCRLGPHTDNIGRGPCSWGLCVQEDSLQA 434
             F  G HYWEV   +      +G +Y  L R R       +G    SW  C++   L+ 
Sbjct: 315 DCFATGRHYWEVDVQEAGAGWWVGAAYASLRR-RGASAAARLGCNRQSW--CLKRYDLEY 371

Query: 435 W--HNGEAQRL-PGVSGRLLGMDLDLASGCLTFYSLEPQTQPLYTFHALFNQPLTPVFWL 491
           W  H+G+  RL P      LG+ LD  +G L FY +      L+TF A F +PL P   L
Sbjct: 372 WAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPALRL 431

Query: 492 LEG 494
            EG
Sbjct: 432 WEG 434


>gi|15208663 tripartite motif protein TRIM14 isoform alpha [Homo
           sapiens]
          Length = 442

 Score =  103 bits (258), Expect = 3e-22
 Identities = 113/423 (26%), Positives = 177/423 (41%), Gaps = 33/423 (7%)

Query: 94  RCPRHG-RPLELFCRTEGRCVCSVCTVRECR------LHERALLDAERLKREAQLRASLE 146
           RCP HG R  ELFCR   RCVC++C V          L   A +  ++L +E   +  L 
Sbjct: 23  RCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLSQECLKQ--LA 80

Query: 147 VTQQQATQAEGQLLELRKQSSQIQNSACILASWVSGKFSSLLQALEIQHTTALRSIEVAK 206
           + +QQ       + ++   + +++ +A    +W+ GKF+ L   L+ +   A + I+   
Sbjct: 81  IKKQQHID---NITQIEDATEKLKANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNT 137

Query: 207 TQALAQARDEEQRLRVHLEAVARHGCRIRELLEQVDE----QTFLQESQLLQPPGPLGPL 262
              L   R++    R  L+ +     R+  + ++ D     Q +    Q +Q    LG L
Sbjct: 138 QLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATEQEMQQQMSLGEL 197

Query: 263 ---TPLQWDEDQQLGDLKQLLSRLCGLLLEEGSHPGAPAKPVDLAPVEAPGPLAPVPSTV 319
               PL ++  +     K L+  +   L          +    L+   +  P   + ++ 
Sbjct: 198 CHPVPLSFEPVKSF--FKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTKPGTLLKTSP 255

Query: 320 CPLRRKLWQNYRNLTFDPVSANRHFYLSRQDQQVKHCRQ--SRGPGGPGSFE-LWQVQCA 376
            P R  L +  R  T DP + +    LS  D+    C    S GP     F+ LWQV   
Sbjct: 256 SPERSLLLKYARTPTLDPDTMHARLRLSA-DRLTVRCGLLGSLGPVPVLRFDALWQVLAR 314

Query: 377 QSFQAGHHYWEVRASDHSVT--LGVSYPQLPRCRLGPHTDNIGRGPCSWGLCVQEDSLQA 434
             F  G HYWEV   +      +G +Y  L R R       +G    SW  C++   L+ 
Sbjct: 315 DCFATGRHYWEVDVQEAGAGWWVGAAYASLRR-RGASAAARLGCNRQSW--CLKRYDLEY 371

Query: 435 W--HNGEAQRL-PGVSGRLLGMDLDLASGCLTFYSLEPQTQPLYTFHALFNQPLTPVFWL 491
           W  H+G+  RL P      LG+ LD  +G L FY +      L+TF A F +PL P   L
Sbjct: 372 WAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPALRL 431

Query: 492 LEG 494
            EG
Sbjct: 432 WEG 434


>gi|15208667 tripartite motif protein TRIM14 isoform alpha [Homo
           sapiens]
          Length = 442

 Score =  103 bits (258), Expect = 3e-22
 Identities = 113/423 (26%), Positives = 177/423 (41%), Gaps = 33/423 (7%)

Query: 94  RCPRHG-RPLELFCRTEGRCVCSVCTVRECR------LHERALLDAERLKREAQLRASLE 146
           RCP HG R  ELFCR   RCVC++C V          L   A +  ++L +E   +  L 
Sbjct: 23  RCPEHGDRVAELFCRRCRRCVCALCPVLGAHRGHPVGLALEAAVHVQKLSQECLKQ--LA 80

Query: 147 VTQQQATQAEGQLLELRKQSSQIQNSACILASWVSGKFSSLLQALEIQHTTALRSIEVAK 206
           + +QQ       + ++   + +++ +A    +W+ GKF+ L   L+ +   A + I+   
Sbjct: 81  IKKQQHID---NITQIEDATEKLKANAESSKTWLKGKFTELRLLLDEEEALAKKFIDKNT 137

Query: 207 TQALAQARDEEQRLRVHLEAVARHGCRIRELLEQVDE----QTFLQESQLLQPPGPLGPL 262
              L   R++    R  L+ +     R+  + ++ D     Q +    Q +Q    LG L
Sbjct: 138 QLTLQVYREQADSCREQLDIMNDLSNRVWSISQEPDPVQRLQAYTATEQEMQQQMSLGEL 197

Query: 263 ---TPLQWDEDQQLGDLKQLLSRLCGLLLEEGSHPGAPAKPVDLAPVEAPGPLAPVPSTV 319
               PL ++  +     K L+  +   L          +    L+   +  P   + ++ 
Sbjct: 198 CHPVPLSFEPVKSF--FKGLVEAVESTLQTPLDIRLKESINCQLSDPSSTKPGTLLKTSP 255

Query: 320 CPLRRKLWQNYRNLTFDPVSANRHFYLSRQDQQVKHCRQ--SRGPGGPGSFE-LWQVQCA 376
            P R  L +  R  T DP + +    LS  D+    C    S GP     F+ LWQV   
Sbjct: 256 SPERSLLLKYARTPTLDPDTMHARLRLSA-DRLTVRCGLLGSLGPVPVLRFDALWQVLAR 314

Query: 377 QSFQAGHHYWEVRASDHSVT--LGVSYPQLPRCRLGPHTDNIGRGPCSWGLCVQEDSLQA 434
             F  G HYWEV   +      +G +Y  L R R       +G    SW  C++   L+ 
Sbjct: 315 DCFATGRHYWEVDVQEAGAGWWVGAAYASLRR-RGASAAARLGCNRQSW--CLKRYDLEY 371

Query: 435 W--HNGEAQRL-PGVSGRLLGMDLDLASGCLTFYSLEPQTQPLYTFHALFNQPLTPVFWL 491
           W  H+G+  RL P      LG+ LD  +G L FY +      L+TF A F +PL P   L
Sbjct: 372 WAFHDGQRSRLRPRDDLDRLGVFLDYEAGVLAFYDVTGGMSHLHTFRATFQEPLYPALRL 431

Query: 492 LEG 494
            EG
Sbjct: 432 WEG 434


>gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]
          Length = 488

 Score =  103 bits (256), Expect = 5e-22
 Identities = 130/523 (24%), Positives = 218/523 (41%), Gaps = 98/523 (18%)

Query: 6   LEEKLTCAICLGLYQDPVTLPCGHNFCGACIRD------WWDRCGKACPECREPFPDGAE 59
           + E++TC ICL L  +P+++ CGH+FC ACI              ++CP C+  +  G  
Sbjct: 9   IREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPG-N 67

Query: 60  LRRNVALSGVLEVVRAGPARDPGPDPGPGPD-PAARCPRHGRPLELFCRTEGRCVCSVC- 117
           LR N  L+ ++  +R           GPG    A  C  HG  L+LFC+ +G+ +C +C 
Sbjct: 68  LRPNRHLANIVRRLREVVL-------GPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 120

Query: 118 TVRECRLHERALLDAERLKREAQLRASLEVTQQQATQAEGQLLELRKQSSQIQNSACILA 177
             +E R H   L++    + + + + SL+  + +  +AE     +R++ +  +N      
Sbjct: 121 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 180

Query: 178 SWVSGKFSSL-----------LQALEIQHTTALRSIEVAKTQALAQARDEEQRLRVHLEA 226
             +  +F+ L           L+ LE +    LR IE A+   + Q     Q LR  +  
Sbjct: 181 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQT----QSLRELISD 236

Query: 227 VARHGCR--IRELLEQVDEQTFLQESQLLQPPGPLGPLTPLQWDEDQQLGDLKQLLSRLC 284
           + R  C+    ELL+ V + T   E   L+ P  L    P +     +  DLK++L R+C
Sbjct: 237 LERR-CQGSTMELLQDVSDVTERSEFWTLRKPEAL----PTKLRSMFRAPDLKRML-RVC 290

Query: 285 GLLLEEGSHPGAPAKPVDLAPVEAPGPLAPVPSTVCPLRRKLWQNYRNLTFDPVSANRHF 344
             L +  S+                                    + ++T +P +AN + 
Sbjct: 291 RELTDVQSY------------------------------------WVDVTLNPHTANLNL 314

Query: 345 YLSRQDQQVKHC-RQSRGPGGPGSFELWQVQCAQSFQAGHHYWEVRASDHSV-TLGVSYP 402
            L++  +QV+    +  GP          V  +Q F +G HYWEV  +  +   LGV   
Sbjct: 315 VLAKNRRQVRFVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWEVDVAKKTAWILGVCSN 374

Query: 403 QLPRCRLGP----------HTDNIGRGPCS--WGLCVQED-SLQAWHNGEAQRLPG--VS 447
                 LGP          H+      P S  W + +Q +   +A+ +     L    V 
Sbjct: 375 S-----LGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSSPSLLLSMTVP 429

Query: 448 GRLLGMDLDLASGCLTFYSLEPQTQPLYTFHA-LFNQPLTPVF 489
            R +G+ LD  +G ++FY++     P+YTF    F   L P F
Sbjct: 430 PRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYF 472


>gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]
          Length = 516

 Score =  103 bits (256), Expect = 5e-22
 Identities = 130/523 (24%), Positives = 218/523 (41%), Gaps = 98/523 (18%)

Query: 6   LEEKLTCAICLGLYQDPVTLPCGHNFCGACIRD------WWDRCGKACPECREPFPDGAE 59
           + E++TC ICL L  +P+++ CGH+FC ACI              ++CP C+  +  G  
Sbjct: 37  IREEVTCPICLELLTEPLSIDCGHSFCQACITPNGRESVIGQEGERSCPVCQTSYQPG-N 95

Query: 60  LRRNVALSGVLEVVRAGPARDPGPDPGPGPD-PAARCPRHGRPLELFCRTEGRCVCSVC- 117
           LR N  L+ ++  +R           GPG    A  C  HG  L+LFC+ +G+ +C +C 
Sbjct: 96  LRPNRHLANIVRRLREVVL-------GPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCE 148

Query: 118 TVRECRLHERALLDAERLKREAQLRASLEVTQQQATQAEGQLLELRKQSSQIQNSACILA 177
             +E R H   L++    + + + + SL+  + +  +AE     +R++ +  +N      
Sbjct: 149 RSQEHRGHHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPER 208

Query: 178 SWVSGKFSSL-----------LQALEIQHTTALRSIEVAKTQALAQARDEEQRLRVHLEA 226
             +  +F+ L           L+ LE +    LR IE A+   + Q     Q LR  +  
Sbjct: 209 CRIQTEFNQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQT----QSLRELISD 264

Query: 227 VARHGCR--IRELLEQVDEQTFLQESQLLQPPGPLGPLTPLQWDEDQQLGDLKQLLSRLC 284
           + R  C+    ELL+ V + T   E   L+ P  L    P +     +  DLK++L R+C
Sbjct: 265 LERR-CQGSTMELLQDVSDVTERSEFWTLRKPEAL----PTKLRSMFRAPDLKRML-RVC 318

Query: 285 GLLLEEGSHPGAPAKPVDLAPVEAPGPLAPVPSTVCPLRRKLWQNYRNLTFDPVSANRHF 344
             L +  S+                                    + ++T +P +AN + 
Sbjct: 319 RELTDVQSY------------------------------------WVDVTLNPHTANLNL 342

Query: 345 YLSRQDQQVKHC-RQSRGPGGPGSFELWQVQCAQSFQAGHHYWEVRASDHSV-TLGVSYP 402
            L++  +QV+    +  GP          V  +Q F +G HYWEV  +  +   LGV   
Sbjct: 343 VLAKNRRQVRFVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWEVDVAKKTAWILGVCSN 402

Query: 403 QLPRCRLGP----------HTDNIGRGPCS--WGLCVQED-SLQAWHNGEAQRLPG--VS 447
                 LGP          H+      P S  W + +Q +   +A+ +     L    V 
Sbjct: 403 S-----LGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSSPSLLLSMTVP 457

Query: 448 GRLLGMDLDLASGCLTFYSLEPQTQPLYTFHA-LFNQPLTPVF 489
            R +G+ LD  +G ++FY++     P+YTF    F   L P F
Sbjct: 458 PRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYF 500


>gi|15208660 tripartite motif protein 21 [Homo sapiens]
          Length = 475

 Score =  101 bits (251), Expect = 2e-21
 Identities = 128/499 (25%), Positives = 203/499 (40%), Gaps = 75/499 (15%)

Query: 5   LLEEKLTCAICLGLYQDPVTLPCGHNFCGACIRDWWDRCGKACPECREPFPDGAELRRNV 64
           ++ E++TC ICL  + +PV++ CGH+FC  CI       G  CP CR+ F     LR N 
Sbjct: 9   MMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGSVCPVCRQRFL-LKNLRPNR 67

Query: 65  ALSGVLEVVR--AGPARDPGPDPGPGPDPAARCPRHGRPLELFCRTEGRCVCSVCTVREC 122
            L+ ++  ++  +  AR+             RC  HG  L LFC  +G+ +C VC   + 
Sbjct: 68  QLANMVNNLKEISQEARE--------GTQGERCAVHGERLHLFCEKDGKALCWVCA--QS 117

Query: 123 RLH-ERALLDAERLKREAQLRASLEVTQQQATQAEGQLLELRKQSSQIQNSACILASWVS 181
           R H + A++  E            E  Q+   + +  L ELR++                
Sbjct: 118 RKHRDHAMVPLE------------EAAQEYQEKLQVALGELRRK---------------- 149

Query: 182 GKFSSLLQALEIQHTTALRSIEVAKTQALAQARDEEQRLRVHLEAVARHGCRIRELLEQV 241
                L + LE         +E+A  +A  +   E Q+ R+H E V +    + E   Q+
Sbjct: 150 ---QELAEKLE---------VEIAIKRADWKKTVETQKSRIHAEFVQQKNFLVEEEQRQL 197

Query: 242 DEQTFLQESQLLQPPGPLGPLTPLQWDEDQQLGDLKQLLSRLCGL----LLEEGSHPGAP 297
            E    +  QL      LG        + Q L +L   L R C      LL+E       
Sbjct: 198 QELEKDEREQL----RILGEKEAKLAQQSQALQELISELDRRCHSSALELLQEVIIVLER 253

Query: 298 AKPVDLAPVEAPGPLAPVPSTVCPLRRKLWQNYRNLTFDPVSANRHFYLSRQDQQVK-HC 356
           ++  +L  ++   P       V  L++ L     ++T DP +AN    LS   +QV+   
Sbjct: 254 SESWNLKDLDITSPELRSVCHVPGLKKMLRTCAVHITLDPDTANPWLILSEDRRQVRLGD 313

Query: 357 RQSRGPGGPGSFELW-QVQCAQSFQAGHHYWEVRASDHSV-TLGVSYPQLPRCRLGPHTD 414
            Q   PG    F+ +  V  AQ F +G HYWEV  +      LGV    + R      + 
Sbjct: 314 TQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDVTGKEAWDLGVCRDSVRRKGHFLLSS 373

Query: 415 NIGRGPCSWGLCVQEDSLQAWHNGEAQRLP---GVSGRLLGMDLDLASGCLTFYSLEPQT 471
             G     W + +   + Q +  G   + P    V    +G+ LD  +G ++FY++    
Sbjct: 374 KSG----FWTIWLW--NKQKYEAGTYPQTPLHLQVPPCQVGIFLDYEAGMVSFYNITDHG 427

Query: 472 QPLYTF-HALFNQPLTPVF 489
             +Y+F    F  PL P F
Sbjct: 428 SLIYSFSECAFTGPLRPFF 446


>gi|217035095 tripartite motif-containing 62 [Homo sapiens]
          Length = 475

 Score =  100 bits (250), Expect = 2e-21
 Identities = 131/505 (25%), Positives = 205/505 (40%), Gaps = 77/505 (15%)

Query: 6   LEEKLTCAICLGLYQDPVTLPCGHNFCGACIRDWWDR----CGKACPECREPFPDGAELR 61
           L+++L C+ICL +YQDPV+L C H FC  CI + W R      + CPECR  F + A L 
Sbjct: 5   LKDELLCSICLSIYQDPVSLGCEHYFCRRCITEHWVRQEAQGARDCPECRRTFAEPA-LA 63

Query: 62  RNVALSGVLEVVRAGPARDPGPDPGPGPDPAAR-CPRHGRPLELFCRTEGRCVCSVCTVR 120
            ++ L+ ++E   + P      D       AAR C  H + ++LFC T+   +C  C   
Sbjct: 64  PSLKLANIVERYSSFPL-----DAILNARRAARPCQAHDK-VKLFCLTDRALLCFFCD-- 115

Query: 121 ECRLHER----ALLDA-ERLKREAQLRASLEVTQQQATQAEGQLLELRKQSSQIQNSACI 175
           E  LHE+     + DA + L+RE  L+  L+  Q    +    L  L++Q ++ ++S   
Sbjct: 116 EPALHEQHQVTGIDDAFDELQRE--LKDQLQALQDSEREHTEALQLLKRQLAETKSSTKS 173

Query: 176 LASWVSGKFSSLLQALEIQHTTALRSIEVAKTQALAQARDEEQRLRVHLEAVARHGCRIR 235
           L + +   F  L + L  +    L  +E    + L     + QR    L  V      ++
Sbjct: 174 LRTTIGEAFERLHRLLRERQKAMLEELEADTARTLTDIEQKVQRYSQQLRKVQEGAQILQ 233

Query: 236 ELLEQVDEQTFLQESQLLQPPGPLGPLTPLQWDEDQQLGDLKQLLSRLCGLLLEEGSHPG 295
           E L + D  TF                          L  +  L  RL G + E      
Sbjct: 234 ERLAETDRHTF--------------------------LAGVASLSERLKGKIHETN---- 263

Query: 296 APAKPVDLAPVEAPGPLAPVPSTVCPLRRKLWQNYR----NLTFDPVSANRHFYLSRQDQ 351
                 D    +  GPL         + + L+Q+       LT DP +A++   LS    
Sbjct: 264 --LTYEDFPTSKYTGPLQ------YTIWKSLFQDIHPVPAALTLDPGTAHQRLILSDDCT 315

Query: 352 QVKHCRQSRGP--GGPGSFEL-WQVQCAQSFQAGHHYWEVRASDHSV-TLGVSYPQLPRC 407
            V +      P    P  F++   V  +++F +G HYWEV  ++ +   +G+++    R 
Sbjct: 316 IVAYGNLHPQPLQDSPKRFDVEVSVLGSEAFSSGVHYWEVVVAEKTQWVIGLAHEAASR- 374

Query: 408 RLGPHTDNIGRGPCSWGLC-VQEDSLQAWHNGEAQRLPGVSGRL--LGMDLDLASGCLTF 464
                  +I   P     C V  D  Q     E      V  +L  +G+ LD   G L F
Sbjct: 375 -----KGSIQIQPSRGFYCIVMHDGNQYSACTEPWTRLNVRDKLDKVGVFLDYDQGLLIF 429

Query: 465 YSLEPQTQPLYTFHALFNQPLTPVF 489
           Y+ +  +  LYTF   F   L   F
Sbjct: 430 YNADDMSW-LYTFREKFPGKLCSYF 453


>gi|16076875 tripartite motif-containing 7 isoform 4 [Homo sapiens]
          Length = 221

 Score =  100 bits (248), Expect = 4e-21
 Identities = 62/184 (33%), Positives = 95/184 (51%), Gaps = 21/184 (11%)

Query: 6   LEEKLTCAICLGLYQDPVTLPCGHNFCGACIRDWWDRCGKA--------------CPECR 51
           L+ + TC+ICL L+++PV++ CGH+FC ACI   W+R G                CP+CR
Sbjct: 23  LQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPCPQCR 82

Query: 52  EPFPDGAELRRNVALSGVLEVVR--AGPARDP---GPDPGPGPDPAARCPRHGRPLELFC 106
           EP    ++LR N  L+ V  ++R  + PA  P   G         AARC +HG P +L+C
Sbjct: 83  EP-ARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHGEPFKLYC 141

Query: 107 RTEGRCVCSVC-TVRECRLHERALLDAERLKREAQLRASLEVTQQQATQAEGQLLELRKQ 165
           + +GR +C VC   RE R H    LD    + +  L + L V +++    E      +K+
Sbjct: 142 QDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRSTEKKE 201

Query: 166 SSQI 169
           S ++
Sbjct: 202 SKEL 205


>gi|198442878 tripartite motif-containing 17 isoform 3 [Homo
           sapiens]
          Length = 343

 Score = 98.6 bits (244), Expect = 1e-20
 Identities = 86/271 (31%), Positives = 126/271 (46%), Gaps = 44/271 (16%)

Query: 3   AQLLEEKLTCAICLGLYQDPVTLPCGHNFCGACIRDWWDRC-GK----------ACPECR 51
           A+ L+E+ TC+ICL  + DPV   CGHNFC ACI+  W++  GK           CPECR
Sbjct: 7   ARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECR 66

Query: 52  EPFPDGAELRRNVALSGVLEVVRAGPARDPGPDPGPGPDPAARCPRHGRPLELFCRTEGR 111
           E  P    L  N  L+ V E+ +            PG      C  H  PL+LFC+ +  
Sbjct: 67  EMSPQ-RNLLPNRLLTKVAEMAQ----------QHPGLQKQDLCQEHHEPLKLFCQKDQS 115

Query: 112 CVCSVC-TVRECRLHERALLDAERLKR--EAQLRASLEVTQQQATQAEGQLLELRKQSSQ 168
            +C VC   RE RLH   +L AE   +  + +L   +E  ++Q T+  G L    +QS  
Sbjct: 116 PICVVCRESREHRLHR--VLPAEEAVQGYKLKLEEDMEYLREQITRT-GNLQAREEQS-- 170

Query: 169 IQNSACILASWVSGKFSSLLQALEIQHTTALRSIEVAKTQALAQARDEEQ-----RLRVH 223
                  LA W  GK     + + ++    +    V + Q L QA + E+     RLR  
Sbjct: 171 -------LAEW-QGKVKERRERIVLEF-EKMNLYLVEEEQRLLQALETEEEETASRLRES 221

Query: 224 LEAVARHGCRIRELLEQVDEQTFLQESQLLQ 254
           +  + R G  +  LL Q++E++     Q+LQ
Sbjct: 222 VACLDRQGHSLELLLLQLEERSTQGPLQMLQ 252


>gi|157426898 tripartite motif-containing 10 isoform 1 [Homo
           sapiens]
          Length = 481

 Score = 97.1 bits (240), Expect = 4e-20
 Identities = 129/515 (25%), Positives = 198/515 (38%), Gaps = 83/515 (16%)

Query: 6   LEEKLTCAICLGLYQDPVTLPCGHNFCGACIRDWWDRCGK------ACPECREPFPDGAE 59
           L +++ C IC G  ++PVT+ CGHNFC AC+  + +  G        CP C+EPF  G+ 
Sbjct: 10  LADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDLEESPTCPLCKEPFRPGS- 68

Query: 60  LRRNVALSGVLEVVRAGPARDPGPDPGPGPDPAARCPRHGRPLELFCRTEGRCVCSVCTV 119
            R N  L+ V+E +            G G +    C  HG  +  FC  +   +C VC  
Sbjct: 69  FRPNWQLANVVENIERLQLVST---LGLGEEDV--CQEHGEKIYFFCEDDEMQLCVVC-- 121

Query: 120 RECRLHE----RALLDAERLKREAQLRASLEVTQQQATQAEGQLLELRKQSSQIQNSACI 175
           RE   H     R L DA    RE Q+   L+  +++  + +       K+   +      
Sbjct: 122 REAGEHATHTMRFLEDAAAPYRE-QIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQVST 180

Query: 176 LASWVSGKFSSLLQALEIQHTTALRSIEVAKTQALAQARDEEQRLRVHLEAVARHGCRIR 235
               V  +F+ L + LE Q +  L  +E      L Q RDE   L      VA   CR  
Sbjct: 181 KRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQ-RDEFDLL------VAGEICRFS 233

Query: 236 ELLEQVDEQTFLQESQLLQPPGPLGPLTPLQWDEDQQLGDLKQLLSRLCGLLLEEGSHPG 295
            L+E+++E+      +LL                     D++  L R             
Sbjct: 234 ALIEELEEKNERPARELLT--------------------DIRSTLIRC---------ETR 264

Query: 296 APAKPVDLAPVEAPGPLAPVPSTVCPLRRKLWQNYRNLTF-----------DPVSANRHF 344
              KPV ++P E    +   P    PL+R++      L F           DP +++   
Sbjct: 265 KCRKPVAVSP-ELGQRIRDFPQQALPLQREMKMFLEKLCFELDYEPAHISLDPQTSHPKL 323

Query: 345 YLSRQDQQVKHC-RQSRGPGGPGSFELWQVQCAQS-FQAGHHYWEVR---ASDHSVTLGV 399
            LS   Q+ +   +    P  P  F+      A +    G H W V    A   S T+GV
Sbjct: 324 LLSEDHQRAQFSYKWQNSPDNPQRFDRATCVLAHTGITGGRHTWVVSIDLAHGGSCTVGV 383

Query: 400 SYPQLPR---CRLGPHTDNIGRGPCSWGLCVQEDSLQAWHNGEAQRLPGVSGRLLGMDLD 456
               + R    RL P  + +     +WG      S       + Q       R + + LD
Sbjct: 384 VSEDVQRKGELRLRPE-EGVWAVRLAWGFVSALGSFPTRLTLKEQP------RQVRVSLD 436

Query: 457 LASGCLTFYSLEPQTQPLYTFHALFNQPLTPVFWL 491
              G +TF +   + +P+YTF A F + + P F L
Sbjct: 437 YEVGWVTFTNAVTR-EPIYTFTASFTRKVIPFFGL 470


>gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens]
          Length = 500

 Score = 96.7 bits (239), Expect = 5e-20
 Identities = 125/504 (24%), Positives = 201/504 (39%), Gaps = 84/504 (16%)

Query: 9   KLTCAICLGLYQDPVTLPCGHNFCGACIRDWWDRCGKA--CPECREPFPDGAELRRNVAL 66
           +L C +C   ++DP+ L CGHNFC ACI+D+W    K   CPEC+           N  L
Sbjct: 38  ELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRLQAKETFCPECK-MLCQYNNCTFNPVL 96

Query: 67  SGVLEVVRAGPARDPGPDPGPGPDPAARCPRHGRPLELFCRTEGRCVCSVCTVRECRLHE 126
             ++E ++  P     P          +CP HG  L+LF + +G+ +C  C        +
Sbjct: 97  DKLVEKIKKLPLLKGHP----------QCPEHGENLKLFSKPDGKLICFQC--------K 138

Query: 127 RALLDAERLKREAQLRASLEVTQQQATQAEGQLLELRKQSSQIQNSACILASWVSGKFSS 186
            A L   + K   Q+  ++    ++    +GQL    K+   ++N      +        
Sbjct: 139 DARLSVGQSKEFLQISDAVHFFTEELAIQQGQLETTLKELQTLRNMQKEAIAAHKENKLH 198

Query: 187 LLQALEIQHTTALRSIEVAKTQALAQARDEEQRLRVHLEAVARHGCRIRELLEQVDEQTF 246
           L Q + ++     + +   +   L + R+E + L   +E            L Q+ EQ  
Sbjct: 199 LQQHVSMEFLKLHQFLHSKEKDILTELREEGKALNEEMEL----------NLSQLQEQCL 248

Query: 247 LQESQLLQPPGPLGPLTPLQWDEDQQ-----LGDLKQLLSRLCGLLLEEGSHPGAPAKPV 301
           L +  L+           +Q   +QQ     L D+  LL       LE+G    A  + +
Sbjct: 249 LAKDMLVS----------IQAKTEQQNSFDFLKDITTLLHS-----LEQGMKVLATRELI 293

Query: 302 D--LAPVEAPGPL-----APVPSTVCPLRRKLWQNYRNLTFDPVSANRHFYLSRQDQQVK 354
              L   +  GP+       +  T+CP           LT DP +A+ +  LS+    V 
Sbjct: 294 SRKLNLGQYKGPIQYMVWREMQDTLCP-------GLSPLTLDPKTAHPNLVLSKSQTSVW 346

Query: 355 HCRQSR-GPGGPGSFE-LWQVQCAQSFQAGHHYWEVR-ASDHSVTLGVSYPQLPRCRLGP 411
           H    +  P  P  F+    V  ++ F +G  YWEV  A     T+GV    + R    P
Sbjct: 347 HGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVAKKTKWTVGVVRESIIRKGSCP 406

Query: 412 HTDNIGRGPCSWGLCVQEDSLQAWHNGEAQRLPGVSGRL------LGMDLDLASGCLTFY 465
            T   G     W L ++  +     + +A  LP  S  L      +G+ LD   G L+FY
Sbjct: 407 LTPEQG----FWLLRLRNQT-----DLKALDLPSFSLTLTNNLDKVGIYLDYEGGQLSFY 457

Query: 466 SLEPQTQPLYTFHALFNQPLTPVF 489
           + +  T  +YTF   F + L P F
Sbjct: 458 NAKTMTH-IYTFSNTFMEKLYPYF 480


>gi|37622899 ring finger protein 137 [Homo sapiens]
          Length = 485

 Score = 94.0 bits (232), Expect = 3e-19
 Identities = 102/442 (23%), Positives = 173/442 (39%), Gaps = 92/442 (20%)

Query: 4   QLLEEKLTCAICLGLYQDPVTLPCGHNFCGACIRDWWD------RCGKACPECREPFPDG 57
           + + E++ C IC+   ++P+++ CGH+FC +C+   W+        G  CP CR P    
Sbjct: 8   EAIVEEVACPICMTFLREPMSIDCGHSFCHSCLSGLWEIPGESQNWGYTCPLCRAPV-QP 66

Query: 58  AELRRNVALSGVLEVVRAGPARDPGPDPGPGPDPAARCPRHGRPLELFCRTEGRCVCSVC 117
             LR N  L+ V+E VR          PG G      C RHG  L++FC+ +   +C  C
Sbjct: 67  RNLRPNWQLANVVEKVRLLRLH-----PGMGL-KGDLCERHGEKLKMFCKEDVLIMCEAC 120

Query: 118 TVR------------------ECRLHERALLDAERLKREAQLRASLEVTQQQATQAEGQL 159
           +                    +  LHE      E LK+E +    LEV +++ T      
Sbjct: 121 SQSPEHEAHSVVPMEDVAWEYKWELHEA----LEHLKKEQEEAWKLEVGERKRTATWKIQ 176

Query: 160 LELRKQSSQIQNSACILASWVSGKFSSLLQALEIQHTTALRSIEVAKTQALAQARDEEQR 219
           +E RKQS            W   K+  LL+  +  H      +  A      +A +  Q+
Sbjct: 177 VETRKQS----------IVWEFEKYQRLLEKKQPPHRQLGAEVAAALASLQREAAETMQK 226

Query: 220 LRVHLEAVARHGCRIRELLEQVDEQTFLQESQLLQPPGPLGPLTPLQWDEDQQLGDLKQL 279
           L ++   + +    +  ++ ++ E++                  P++W     L D++++
Sbjct: 227 LELNHSELIQQSQVLWRMIAELKERS----------------QRPVRW----MLQDIQEV 266

Query: 280 LSRLCGLLLEEGSHPGAPAKPVDLAPVEAPGPLAPVPSTVC---PLRRKLWQNYRNLTFD 336
           L+R     L++                  P P++    T C    LR  L     ++  D
Sbjct: 267 LNRSKSWSLQQ------------------PEPISLELKTDCRVLGLREILKTYAADVRLD 308

Query: 337 PVSANRHFYLSRQDQQVKH-CRQSRGPGGPGSFELWQVQC-AQSFQAGHHYWEVRASDHS 394
           P +A     +S   ++V +     + P  P  F  + +   +Q   +G HYWEV   D S
Sbjct: 309 PDTAYSRLIVSEDRKRVHYGDTNQKLPDNPERFYRYNIVLGSQCISSGRHYWEVEVGDRS 368

Query: 395 V-TLGVSYPQLPR---CRLGPH 412
              LGV    + R     L PH
Sbjct: 369 EWGLGVCKQNVDRKEVVYLSPH 390


>gi|15011946 tripartite motif protein TRIM5 isoform delta [Homo
           sapiens]
          Length = 326

 Score = 92.8 bits (229), Expect = 7e-19
 Identities = 65/256 (25%), Positives = 122/256 (47%), Gaps = 23/256 (8%)

Query: 6   LEEKLTCAICLGLYQDPVTLPCGHNFCGACI-----RDWWDRCGKACPECREPF-PDGAE 59
           ++E++TC ICL L   P++L CGH+FC AC+     +   D+   +CP CR  + P+   
Sbjct: 9   VKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQPENIR 68

Query: 60  LRRNVALSGVLEVVRAGPARDPGPDPGPGPDPAARCPRHGRPLELFCRTEGRCVCSVC-T 118
             R+VA   ++E +R            P       C RHG  L LFC+ +G+ +C +C  
Sbjct: 69  PNRHVA--NIVEKLREVKL-------SPEGQKVDHCARHGEKLLLFCQEDGKVICWLCER 119

Query: 119 VRECRLHERALLDAERLKREAQLRASLEVTQQQATQAEGQLLELRKQSSQIQNSACILAS 178
            +E R H   L +    + + +L+A+LE+ +Q+  +AE    ++R++ +  +       +
Sbjct: 120 SQEHRGHHTFLTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKT 179

Query: 179 WVSGKFSSLLQALEIQHTTALRSIEVAKTQALAQARDEEQRLRVHLEAVARHGCRIRELL 238
            V   F  L   L+ + +  L+++E  +   L    + E  +    ++       +REL+
Sbjct: 180 NVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQS-------LRELI 232

Query: 239 EQVDEQTFLQESQLLQ 254
             ++ +      +LLQ
Sbjct: 233 SDLEHRLQGSVMELLQ 248


>gi|15011944 tripartite motif protein TRIM5 isoform gamma [Homo
           sapiens]
          Length = 347

 Score = 92.8 bits (229), Expect = 7e-19
 Identities = 65/256 (25%), Positives = 122/256 (47%), Gaps = 23/256 (8%)

Query: 6   LEEKLTCAICLGLYQDPVTLPCGHNFCGACI-----RDWWDRCGKACPECREPF-PDGAE 59
           ++E++TC ICL L   P++L CGH+FC AC+     +   D+   +CP CR  + P+   
Sbjct: 9   VKEEVTCPICLELLTQPLSLDCGHSFCQACLTANHKKSMLDKGESSCPVCRISYQPENIR 68

Query: 60  LRRNVALSGVLEVVRAGPARDPGPDPGPGPDPAARCPRHGRPLELFCRTEGRCVCSVC-T 118
             R+VA   ++E +R            P       C RHG  L LFC+ +G+ +C +C  
Sbjct: 69  PNRHVA--NIVEKLREVKL-------SPEGQKVDHCARHGEKLLLFCQEDGKVICWLCER 119

Query: 119 VRECRLHERALLDAERLKREAQLRASLEVTQQQATQAEGQLLELRKQSSQIQNSACILAS 178
            +E R H   L +    + + +L+A+LE+ +Q+  +AE    ++R++ +  +       +
Sbjct: 120 SQEHRGHHTFLTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKT 179

Query: 179 WVSGKFSSLLQALEIQHTTALRSIEVAKTQALAQARDEEQRLRVHLEAVARHGCRIRELL 238
            V   F  L   L+ + +  L+++E  +   L    + E  +    ++       +REL+
Sbjct: 180 NVLADFEQLRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQS-------LRELI 232

Query: 239 EQVDEQTFLQESQLLQ 254
             ++ +      +LLQ
Sbjct: 233 SDLEHRLQGSVMELLQ 248


>gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]
          Length = 450

 Score = 92.0 bits (227), Expect = 1e-18
 Identities = 134/494 (27%), Positives = 203/494 (41%), Gaps = 95/494 (19%)

Query: 27  CGHNFCGACIRDWWDRC-GK----------ACPECREPFPDGAELRRNVALSGVLEVVRA 75
           CGHNFC ACI+  W++  GK           CPECRE  P    L  N  L+ V E+ + 
Sbjct: 4   CGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECREMSPQ-RNLLPNRLLTKVAEMAQ- 61

Query: 76  GPARDPGPDPGPGPDPAARCPRHGRPLELFCRTEGRCVCSVC-TVRECRLHERALLDAER 134
                      PG      C  H  PL+LFC+ +   +C VC   RE RLH   +L AE 
Sbjct: 62  ---------QHPGLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESREHRLHR--VLPAEE 110

Query: 135 LKR--EAQLRASLEVTQQQATQAEGQLLELRKQSSQIQNSACILASWVSGKFSSLLQALE 192
             +  + +L   +E  ++Q T+  G L    +QS         LA W  GK     + + 
Sbjct: 111 AVQGYKLKLEEDMEYLREQITRT-GNLQAREEQS---------LAEW-QGKVKERRERIV 159

Query: 193 IQHTTALRSIEVAKTQALAQARDEEQ-----RLRVHLEAVARHGCRIRELLEQVDEQTFL 247
           ++    +    V + Q L QA + E+     RLR  +  + R G  +  LL Q++E++  
Sbjct: 160 LEF-EKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLEERS-- 216

Query: 248 QESQLLQPPGPLGPLTPLQWDEDQQLGDLKQLLSRLCGLLLEEGSHPGAPAKPVDLAPVE 307
                    GPL           Q L D+K+ LSR   + ++       P    ++AP  
Sbjct: 217 -------TQGPL-----------QMLQDMKEPLSRKNNVSVQ------CP----EVAPPT 248

Query: 308 APGPLAPVPSTVCPLRRKLWQNYRNLTFDPVSANRH--FYLSRQDQQVKHCRQSRGPGGP 365
            P  +  VP  +  LR  L     ++  D  SA  +   Y SRQ + +    +  G    
Sbjct: 249 RPRTVCRVPGQIEVLRGFL----EDVVPDATSAYPYLLLYESRQRRYLGSSPEGSGFCSK 304

Query: 366 GSFELWQVQCAQ-SFQAGHHYWEVR---ASDHSVTLGVSYPQLPRCRLGPHTDNIGRGPC 421
             F  +     Q +F +G HYWEV      D    LGV    + R       D + + P 
Sbjct: 305 DRFVAYPCAVGQTAFSSGRHYWEVGMNITGDALWALGVCRDNVSR------KDRVPKCPE 358

Query: 422 SWGLCVQEDSLQAWHNGEAQRLPGV---SGRLLGMDLDLASGCLTFYSLEPQTQPLYTF- 477
           +    VQ      + +  +   P +       +G+ LD  +G ++FYS+   +  L+T+ 
Sbjct: 359 NGFWVVQLSKGTKYLSTFSALTPVMLMEPPSHMGIFLDFEAGEVSFYSVSDGSH-LHTYS 417

Query: 478 HALFNQPLTPVFWL 491
            A F  PL P F L
Sbjct: 418 QATFPGPLQPFFCL 431


>gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 127/531 (23%), Positives = 225/531 (42%), Gaps = 101/531 (19%)

Query: 1   MAAQLL---EEKLTCAICLGLYQDPVTLPCGHNFCGACI----RDWWDRCG--KACPECR 51
           MA+++L   +E++TC ICL L  +P++L CGH+ C ACI    ++     G   +CP C 
Sbjct: 1   MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 60

Query: 52  EPFPDGAELRRNVALSGVLEVVRAGPARDPGPDPGPGPDPAARCPRHGRPLELFCRTEGR 111
             +     L+ N  L+ ++E ++        PD G   D    C  HG  L LFC+ + +
Sbjct: 61  ISY-SFEHLQANQHLANIVERLKEVKL---SPDNGKKRD---LCDHHGEKLLLFCKEDRK 113

Query: 112 CVCSVC-TVRECRLHERALLDAERLKREAQLRASLEVTQQQATQAEGQLLELRKQSSQIQ 170
            +C +C   +E R H   L +    + + +L+A L+  +++  +AE    ++R++ +  +
Sbjct: 114 VICWLCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWK 173

Query: 171 NSACILASWVSGKFSSLLQALEIQHTTALRSIEVAKTQALAQARDEEQRLRVHLEAVARH 230
                    +  +F  L   L  +    L+ +E  + + L +  + E  L    + V   
Sbjct: 174 YQVQTERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLV--- 230

Query: 231 GCRIRELLEQVDEQTFLQESQLLQPPGPLGPLTPLQWDEDQQLGDLKQLLSRLCGLLLEE 290
               REL+  V+ ++     +LLQ    +     ++W E  +L   K +  +L  +    
Sbjct: 231 ----RELISDVECRSQWSTMELLQDMSGI-----MKWSEIWRLKKPKMVSKKLKTVF--- 278

Query: 291 GSHPGAPAKPVDLAPVEAPGPLAPVPSTVCPLRRKLWQ---NYRNLTFDPVSANRHFYLS 347
                                 AP  S +  + R+L      + ++T + V+ N +  LS
Sbjct: 279 ---------------------HAPDLSRMLQMFRELTAVRCYWVDVTLNSVNLNLNLVLS 317

Query: 348 RQDQQVKHCRQSRGPGGPGSFELWQVQC-------AQSFQAGHHYWEVRASDHSV-TLGV 399
              +QV             S  +W  QC       +Q F +G HYWEV  S  +   LGV
Sbjct: 318 EDQRQVI------------SVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKTAWILGV 365

Query: 400 ---SYPQ-----LPRC--RLGPHTDN--------IG-RGPCSWGLCVQEDSLQAWHNGEA 440
              +Y +     + RC  R   +T          IG +  C +G  V E+SL +  + E 
Sbjct: 366 YCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYG--VFEESLSS--DPEV 421

Query: 441 QRLP-GVSGRLLGMDLDLASGCLTFYSLEPQTQPLYTF-HALFNQPLTPVF 489
             L   V    +G+ LD  +G ++F+++      +Y F    F+QP+ P F
Sbjct: 422 LTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYF 472


>gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 127/531 (23%), Positives = 225/531 (42%), Gaps = 101/531 (19%)

Query: 1   MAAQLL---EEKLTCAICLGLYQDPVTLPCGHNFCGACI----RDWWDRCG--KACPECR 51
           MA+++L   +E++TC ICL L  +P++L CGH+ C ACI    ++     G   +CP C 
Sbjct: 1   MASKILLNVQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSSCPVCG 60

Query: 52  EPFPDGAELRRNVALSGVLEVVRAGPARDPGPDPGPGPDPAARCPRHGRPLELFCRTEGR 111
             +     L+ N  L+ ++E ++        PD G   D    C  HG  L LFC+ + +
Sbjct: 61  ISY-SFEHLQANQHLANIVERLKEVKL---SPDNGKKRD---LCDHHGEKLLLFCKEDRK 113

Query: 112 CVCSVC-TVRECRLHERALLDAERLKREAQLRASLEVTQQQATQAEGQLLELRKQSSQIQ 170
            +C +C   +E R H   L +    + + +L+A L+  +++  +AE    ++R++ +  +
Sbjct: 114 VICWLCERSQEHRGHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWK 173

Query: 171 NSACILASWVSGKFSSLLQALEIQHTTALRSIEVAKTQALAQARDEEQRLRVHLEAVARH 230
                    +  +F  L   L  +    L+ +E  + + L +  + E  L    + V   
Sbjct: 174 YQVQTERQRIQTEFDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLV--- 230

Query: 231 GCRIRELLEQVDEQTFLQESQLLQPPGPLGPLTPLQWDEDQQLGDLKQLLSRLCGLLLEE 290
               REL+  V+ ++     +LLQ    +     ++W E  +L   K +  +L  +    
Sbjct: 231 ----RELISDVECRSQWSTMELLQDMSGI-----MKWSEIWRLKKPKMVSKKLKTVF--- 278

Query: 291 GSHPGAPAKPVDLAPVEAPGPLAPVPSTVCPLRRKLWQ---NYRNLTFDPVSANRHFYLS 347
                                 AP  S +  + R+L      + ++T + V+ N +  LS
Sbjct: 279 ---------------------HAPDLSRMLQMFRELTAVRCYWVDVTLNSVNLNLNLVLS 317

Query: 348 RQDQQVKHCRQSRGPGGPGSFELWQVQC-------AQSFQAGHHYWEVRASDHSV-TLGV 399
              +QV             S  +W  QC       +Q F +G HYWEV  S  +   LGV
Sbjct: 318 EDQRQVI------------SVPIWPFQCYNYGVLGSQYFSSGKHYWEVDVSKKTAWILGV 365

Query: 400 ---SYPQ-----LPRC--RLGPHTDN--------IG-RGPCSWGLCVQEDSLQAWHNGEA 440
              +Y +     + RC  R   +T          IG +  C +G  V E+SL +  + E 
Sbjct: 366 YCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYG--VFEESLSS--DPEV 421

Query: 441 QRLP-GVSGRLLGMDLDLASGCLTFYSLEPQTQPLYTF-HALFNQPLTPVF 489
             L   V    +G+ LD  +G ++F+++      +Y F    F+QP+ P F
Sbjct: 422 LTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYF 472


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.443 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,475,434
Number of Sequences: 37866
Number of extensions: 1434945
Number of successful extensions: 9198
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 259
Number of HSP's successfully gapped in prelim test: 292
Number of HSP's that attempted gapping in prelim test: 8030
Number of HSP's gapped (non-prelim): 1123
length of query: 517
length of database: 18,247,518
effective HSP length: 107
effective length of query: 410
effective length of database: 14,195,856
effective search space: 5820300960
effective search space used: 5820300960
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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