Guide to the Human Genome
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Search of human proteins with 38569430

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|38569430 activating transcription factor 7 interacting
protein 2 [Homo sapiens]
         (682 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|38569430 activating transcription factor 7 interacting protei...  1357   0.0  
gi|38261962 activating transcription factor 7 interacting protei...   140   3e-33
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    50   9e-06
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    50   9e-06
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    48   3e-05
gi|161016767 mucin 21 [Homo sapiens]                                   46   1e-04
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit...    44   4e-04
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [...    43   0.001
gi|15559211 RE1-silencing transcription factor [Homo sapiens]          43   0.001
gi|238624188 diffuse panbronchiolitis critical region 1 protein ...    42   0.001
gi|109637791 transcription factor-like nuclear regulator [Homo s...    42   0.002
gi|45237195 Janus kinase and microtubule interacting protein 2 [...    41   0.003
gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Hom...    40   0.005
gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo ...    40   0.005
gi|58535453 CDK5 regulatory subunit associated protein 2 isoform...    40   0.009
gi|190341068 forkhead-associated (FHA) phosphopeptide binding do...    40   0.009
gi|72256200 B-cell CLL/lymphoma 9 [Homo sapiens]                       39   0.012
gi|91982772 mucin 17 [Homo sapiens]                                    39   0.016
gi|119372317 xin actin-binding repeat containing 2 isoform 1 [Ho...    39   0.016
gi|27262622 neuron navigator 1 [Homo sapiens]                          39   0.016
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2...    39   0.021
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1...    39   0.021
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu...    38   0.027
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre...    38   0.027
gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens]            38   0.027
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]         38   0.027
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]         38   0.027
gi|154354979 myosin X [Homo sapiens]                                   38   0.027
gi|155030218 PDS5, regulator of cohesion maintenance, homolog A ...    38   0.027
gi|155030216 PDS5, regulator of cohesion maintenance, homolog A ...    38   0.027

>gi|38569430 activating transcription factor 7 interacting protein 2
           [Homo sapiens]
          Length = 682

 Score = 1357 bits (3512), Expect = 0.0
 Identities = 682/682 (100%), Positives = 682/682 (100%)

Query: 1   MASPDRSKRKILKAKKTMPLSCRKQVEMLNKSRNVEALKTAIGSNVPSGNQSFSPSVITR 60
           MASPDRSKRKILKAKKTMPLSCRKQVEMLNKSRNVEALKTAIGSNVPSGNQSFSPSVITR
Sbjct: 1   MASPDRSKRKILKAKKTMPLSCRKQVEMLNKSRNVEALKTAIGSNVPSGNQSFSPSVITR 60

Query: 61  TTEITKCSPSENGASSLDSNKNSISEKSKVFSQNCIKPVEEIVHSETKLEQVVCSYQKPS 120
           TTEITKCSPSENGASSLDSNKNSISEKSKVFSQNCIKPVEEIVHSETKLEQVVCSYQKPS
Sbjct: 61  TTEITKCSPSENGASSLDSNKNSISEKSKVFSQNCIKPVEEIVHSETKLEQVVCSYQKPS 120

Query: 121 RTTESPSRVFTEEAKDSLNTSENDSEHQTNVTRSLFEHEGACSLKSSCCPPSVLSGVVQM 180
           RTTESPSRVFTEEAKDSLNTSENDSEHQTNVTRSLFEHEGACSLKSSCCPPSVLSGVVQM
Sbjct: 121 RTTESPSRVFTEEAKDSLNTSENDSEHQTNVTRSLFEHEGACSLKSSCCPPSVLSGVVQM 180

Query: 181 PESTVTSTVGDKKTDQMVFHLETNSNSESHDKRQSDNILCSEDSGFVPVEKTPNLVNSVT 240
           PESTVTSTVGDKKTDQMVFHLETNSNSESHDKRQSDNILCSEDSGFVPVEKTPNLVNSVT
Sbjct: 181 PESTVTSTVGDKKTDQMVFHLETNSNSESHDKRQSDNILCSEDSGFVPVEKTPNLVNSVT 240

Query: 241 SNNCADDILKTDECSRTSISNCESADSTWQSSLDTNNNSHYQKKRMFSENEENVKRMKTS 300
           SNNCADDILKTDECSRTSISNCESADSTWQSSLDTNNNSHYQKKRMFSENEENVKRMKTS
Sbjct: 241 SNNCADDILKTDECSRTSISNCESADSTWQSSLDTNNNSHYQKKRMFSENEENVKRMKTS 300

Query: 301 EQINENICVSLERQTAFLEQVRHLIQQEIYSINYELFDKKLKELNQRIGKTECRNKHEGI 360
           EQINENICVSLERQTAFLEQVRHLIQQEIYSINYELFDKKLKELNQRIGKTECRNKHEGI
Sbjct: 301 EQINENICVSLERQTAFLEQVRHLIQQEIYSINYELFDKKLKELNQRIGKTECRNKHEGI 360

Query: 361 ADKLLAKIAKLQRRIKTVLLFQRNCLKPNMLSSNGASKVANSEAMILDKNLESVNSPIEK 420
           ADKLLAKIAKLQRRIKTVLLFQRNCLKPNMLSSNGASKVANSEAMILDKNLESVNSPIEK
Sbjct: 361 ADKLLAKIAKLQRRIKTVLLFQRNCLKPNMLSSNGASKVANSEAMILDKNLESVNSPIEK 420

Query: 421 SSVNYEPSNPSEKGSKKINLSSDQNKSVSESNNDDVMLISVESPNLTTPITSNPTDTRKI 480
           SSVNYEPSNPSEKGSKKINLSSDQNKSVSESNNDDVMLISVESPNLTTPITSNPTDTRKI
Sbjct: 421 SSVNYEPSNPSEKGSKKINLSSDQNKSVSESNNDDVMLISVESPNLTTPITSNPTDTRKI 480

Query: 481 TSGNSSNSPNAEVMAVQKKLDSIIDLTKEGLSNCNTESPVSPLESHSKAASNSKETTPLA 540
           TSGNSSNSPNAEVMAVQKKLDSIIDLTKEGLSNCNTESPVSPLESHSKAASNSKETTPLA
Sbjct: 481 TSGNSSNSPNAEVMAVQKKLDSIIDLTKEGLSNCNTESPVSPLESHSKAASNSKETTPLA 540

Query: 541 QNAVQVPESFEHLPPLPEPPAPLPELVDKTRDTLPPQKPELKVKRVFRPNGIALTWNITK 600
           QNAVQVPESFEHLPPLPEPPAPLPELVDKTRDTLPPQKPELKVKRVFRPNGIALTWNITK
Sbjct: 541 QNAVQVPESFEHLPPLPEPPAPLPELVDKTRDTLPPQKPELKVKRVFRPNGIALTWNITK 600

Query: 601 INPKCAPVESYHLFLCHENSNNKLIWKKIGEIKALPLPMACTLSQFLASNRYYFTVQSKD 660
           INPKCAPVESYHLFLCHENSNNKLIWKKIGEIKALPLPMACTLSQFLASNRYYFTVQSKD
Sbjct: 601 INPKCAPVESYHLFLCHENSNNKLIWKKIGEIKALPLPMACTLSQFLASNRYYFTVQSKD 660

Query: 661 IFGRYGPFCDIKSIPGFSENLT 682
           IFGRYGPFCDIKSIPGFSENLT
Sbjct: 661 IFGRYGPFCDIKSIPGFSENLT 682


>gi|38261962 activating transcription factor 7 interacting protein
            [Homo sapiens]
          Length = 1270

 Score =  140 bits (354), Expect = 3e-33
 Identities = 97/344 (28%), Positives = 163/344 (47%), Gaps = 63/344 (18%)

Query: 392  SSNGASKVANSEAMILDKNLESVNSPIEKSSVNYEPSNPSEKGSKK---INLSSDQNKSV 448
            +S+ A + +N+   I ++  +++++ + K + +         GS     I+L+ D  +S 
Sbjct: 918  TSSAAEQNSNTTPRIENQTNKTIDASVSKKAADSTSQCGKATGSDSSGVIDLTMDDEESG 977

Query: 449  SES-----NNDDVMLISVESPNLTTPITSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSI 503
            +       N+  V  +S   P ++ P+           SG  ++ P+   + +     + 
Sbjct: 978  ASQDPKKLNHTPVSTMSSSQP-VSRPLQPIQPAPPLQPSGVPTSGPSQTTIHLLPTAPTT 1036

Query: 504  IDLTKEGLSNCNTESPV--------------------SPLESHSKAASNSKETTPLAQNA 543
            +++T   ++   T  PV                    +PL      A   ++  P     
Sbjct: 1037 VNVTHRPVTQVTTRLPVPRAPANHQVVYTTLPAPPAQAPLRGTVMQAPAVRQVNPQNSVT 1096

Query: 544  VQVPESFEHL--------------------------PPLPEPPAPLPE------LVDKTR 571
            V+VP++  ++                          PP P  PAPLPE      L  +  
Sbjct: 1097 VRVPQTTTYVVNNGLTLGSTGPQLTVHHRPPQVHTEPPRPVHPAPLPEAPQPQRLPPEAA 1156

Query: 572  DTLPPQKPELKVKRVFRPNGIALTWNITKINPKCAPVESYHLFLCHENSNNKLI--WKKI 629
             T  PQKP LK+ RV   NGI L+W++ +++  CA V+SYHL+  HE  +  +   WKKI
Sbjct: 1157 STSLPQKPHLKLARVQSQNGIVLSWSVLEVDRSCATVDSYHLYAYHEEPSATVPSQWKKI 1216

Query: 630  GEIKALPLPMACTLSQFLASNRYYFTVQSKDIFGRYGPFCDIKS 673
            GE+KALPLPMACTL+QF++ ++YYF V++KDI+GR+GPFCD +S
Sbjct: 1217 GEVKALPLPMACTLTQFVSGSKYYFAVRAKDIYGRFGPFCDPQS 1260



 Score = 70.5 bits (171), Expect = 5e-12
 Identities = 119/574 (20%), Positives = 231/574 (40%), Gaps = 115/574 (20%)

Query: 80  NKNSISEKSKVFSQNCIKPVEEIVHSETKLEQVVCSYQKPSRTTESPSRVFTEEA--KDS 137
           +K+S+ EK+K  + N I   EE + ++   +  +CS + P    +    + TE A  +D+
Sbjct: 331 SKDSLDEKNK--ADNNIDANEETLETD---DTTICSDRPPENEKKVEEDIITELALGEDA 385

Query: 138 LNTSENDSEHQTNVTRSLFEHEGACSLKSSCCPPSVLSGVVQMPES-TVTSTVGDKKTDQ 196
           +++S    + + N      E E +  L  +     +   V++  +S  +       +TD+
Sbjct: 386 ISSSMEIDQGEKN------EDETSADLVET-----INENVIEDNKSENILENTDSMETDE 434

Query: 197 MVFHLETNSNSESHDKRQSDNILCSEDSGFVPVEKT-PNLVNSVTSN------------- 242
           ++  LE  + SE       D + C   +  +P+++T P+L   + S+             
Sbjct: 435 IIPILEKLAPSE-------DELTCFSKTSLLPIDETNPDLEEKMESSFGSPSKQESSESL 487

Query: 243 ------------------NCADDILKTDECSRTSISNCESADSTWQSSL--------DTN 276
                             + ++ I + + CS   + + E  +   +            + 
Sbjct: 488 PKEAFLVLSDEEDISGEKDESEVISQNETCSPAEVESNEKDNKPEEEEQVIHEDDERPSE 547

Query: 277 NNSHYQKKRMFSENEENV--KRMKTSEQINE-----NICVSLERQTAFLEQVRHLIQQEI 329
            N   ++KR  SE+ +NV  KR +  E+  E      I    +      + ++ L+++++
Sbjct: 548 KNEFSRRKRSKSEDMDNVQSKRRRYMEEEYEAEFQVKITAKGDINQKLQKVIQWLLEEKL 607

Query: 330 YSINYELFDKKLKELNQRIGKTECRNKHEGIADKLLAKIAKLQRRIKTVL--LFQRNCLK 387
            ++   +FDK L EL  R+ K EC  +H+ +  +L AKIA+L +R +     L +R+   
Sbjct: 608 CALQCAVFDKTLAELKTRVEKIECNKRHKTVLTELQAKIARLTKRFEAAKEDLKKRHEHP 667

Query: 388 PNMLSSNGASKVANSEAMILDKNLESVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNKS 447
           PN   S G             K +  VNS    ++++Y        G+ +  L S +N S
Sbjct: 668 PNPPVSPG-------------KTVNDVNS---NNNMSYR-----NAGTVRQMLESKRNVS 706

Query: 448 VSESNNDDVMLISVESPNLTTP---ITSNPTDTRKITSGNSS-----NSPNAEVMAVQKK 499
            S   +    + +V S NL TP   ++S P     +TSG+ +      +PN   +    +
Sbjct: 707 ESAPPSFQTPVNTVSSTNLVTPPAVVSSQPKLQTPVTSGSLTATSVLPAPNTATVVATTQ 766

Query: 500 LDSIIDLTKEGLS--------NCNTESPVSPLESHSKAASNSKETTPLAQNAVQVPESFE 551
           + S        L              S    L+SH      ++ +  +   +VQ P +  
Sbjct: 767 VPSGNPQPTISLQPLPVILHVPVAVSSQPQLLQSHPGTLVTNQPSGNVEFISVQSPPT-- 824

Query: 552 HLPPLPEPPAPLPELVDKTRDTLPPQKPELKVKR 585
            +  L + P  LP L + T+    P  P   ++R
Sbjct: 825 -VSGLTKNPVSLPSLPNPTKPNNVPSVPSPSIQR 857



 Score = 31.2 bits (69), Expect = 3.3
 Identities = 17/42 (40%), Positives = 28/42 (66%), Gaps = 1/42 (2%)

Query: 1  MASPDRSKRKILKAKKTMPLSCRKQVEMLNKSRNVEALKTAI 42
          M S +  ++K+ KA+KTM +S R+Q+E + K +  E LKT +
Sbjct: 1  MDSLEEPQKKVFKARKTMRVSDRQQLEAVYKVKE-ELLKTDV 41


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 98/487 (20%), Positives = 186/487 (38%), Gaps = 47/487 (9%)

Query: 70   SENGASSLDSNKNSISEKSKVFSQNCIKPVEEIVHSETKLEQVVCSYQKPSRTTESPSRV 129
            S    S  D+ K   S KS + S+   +   E  + +++LE+ + S  K      +  R+
Sbjct: 745  SSTSGSDFDTKKGK-SAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRI 803

Query: 130  FTEEAKDSLNTSENDSEHQTNVTRSLFEHEGACSLKSSCCPPSVLSGVVQMPESTVTSTV 189
                     NT + DS      ++   +++G  +LK+S    S  +   Q  E T +S  
Sbjct: 804  --------PNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERE-TFSSAE 854

Query: 190  GDKKTDQMVFHLETNSNSESHDKRQSDNI--LCSEDSGFVPVEKTPNLVNSVTSNNCADD 247
            G    D  +  L      +      +D +  L  ++  F  +E     V  V        
Sbjct: 855  GTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLE-----VRKVAETKEKSK 909

Query: 248  ILKTDECSRTSISNCESADSTWQSSLDTNNNSHYQKKRMFSENEENVKRMKTSEQINENI 307
             LKT  C +      + A+   +    ++  S   KK+     EE  K     +++    
Sbjct: 910  HLKTKTCKKVQDGLSDIAEKFLKKD-QSDETSEDDKKQSKKGTEEKKKPSDFKKKV---- 964

Query: 308  CVSLERQTAFLEQVRHLIQQEIYSINYELFDKKLKELNQRIGKTECRNKHEGIADKLLAK 367
             + +E+Q          + +     +   F K +K++    G T+   K + I DK   K
Sbjct: 965  -IKMEQQYESSSDGTEKLPEREEICH---FPKGIKQIKN--GTTDGEKKSKKIRDKTSKK 1018

Query: 368  IAKLQRRIKTVLLFQRNC-LKPNMLSSNGASKVANSEAMILDKNL----ESVNSPIEKSS 422
              +L    +       +C    +  S NGA         +L K+     +  +S  EK S
Sbjct: 1019 KDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYS 1078

Query: 423  VNYEPSNPSEKGSKKINLSSDQNKSVSESNNDDVMLISVESPNLTTPITSNPTDTRKITS 482
            +  +  N S+K  K+I L   +N S   +  +      ++S + ++    +  D +K   
Sbjct: 1079 MKEDGCNSSDKRLKRIELRERRNLSSKRNTKE------IQSGSSSSDAEESSEDNKK--K 1130

Query: 483  GNSSNSPNAEVMAVQKKLDSIIDLTKEGLSNCNTESPVSPLE-----SHSKAASNSKETT 537
               ++S    V+  +KK +S+   TK   ++  T S  S +E     S  + +S+ ++  
Sbjct: 1131 KQRTSSKKKAVIVKEKKRNSLRTSTKRKQADI-TSSSSSDIEDDDQNSIGEGSSDEQKIK 1189

Query: 538  PLAQNAV 544
            P+ +N V
Sbjct: 1190 PVTENLV 1196



 Score = 31.2 bits (69), Expect = 3.3
 Identities = 70/392 (17%), Positives = 138/392 (35%), Gaps = 23/392 (5%)

Query: 66   KCSPSENGASSLDSNKNSISEKSKVFSQNCIKPVEEIVHSETKLEQVVCSYQKPSRTTES 125
            K S      SS D+ K S+ E     S   +K +E         ++     Q  S ++++
Sbjct: 1061 KSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDA 1120

Query: 126  PSRVFTEEAKDSLNTSENDSEHQTNVTRSLFEHEGACSLKSSCCPPSVLSGVVQMPESTV 185
                  E ++D+    +  S  +  V   + + +   SL++S           +  ++ +
Sbjct: 1121 E-----ESSEDNKKKKQRTSSKKKAV---IVKEKKRNSLRTS----------TKRKQADI 1162

Query: 186  TSTVGDKKTDQMVFHLETNSNSESHDKRQSDNILCSEDSGFVPVEKTPNLVNSV--TSNN 243
            TS+      D     +   S+ E   K  ++N++ S  +GF        L  SV  T ++
Sbjct: 1163 TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD 1222

Query: 244  CADDILKTDECSRTSISNCESADSTWQSSLDTNNNSHYQKKRMFSENEENVKRMKTSEQI 303
              DD    +  ++  +     A+ +      +++     KKR   +NEEN    +   Q+
Sbjct: 1223 DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQV 1282

Query: 304  NENICVSLERQTAFLEQVRHLIQQEIYSINYELFDKKLKELNQRIGKTECRNKHEGIADK 363
            N       E       + R L  +   S      +KK K    +  K   R K   ++ +
Sbjct: 1283 NSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRK---VSSE 1339

Query: 364  LLAKIAKLQRRIKTVLLFQRNCLKPNMLSSNGASKVANSEAMILDKNLESVNSPIEKSSV 423
                    +  +   +    +  +P   S+  A    N  +    K    +    + SS 
Sbjct: 1340 DSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSE 1399

Query: 424  NYEPSNPSEKGSKKINLSSDQNKSVSESNNDD 455
            N   S   E+  ++     ++ +   E  NDD
Sbjct: 1400 NKSNSEEEEEEKEEEEEEEEEEEEEEEDENDD 1431


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 98/487 (20%), Positives = 186/487 (38%), Gaps = 47/487 (9%)

Query: 70   SENGASSLDSNKNSISEKSKVFSQNCIKPVEEIVHSETKLEQVVCSYQKPSRTTESPSRV 129
            S    S  D+ K   S KS + S+   +   E  + +++LE+ + S  K      +  R+
Sbjct: 783  SSTSGSDFDTKKGK-SAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRI 841

Query: 130  FTEEAKDSLNTSENDSEHQTNVTRSLFEHEGACSLKSSCCPPSVLSGVVQMPESTVTSTV 189
                     NT + DS      ++   +++G  +LK+S    S  +   Q  E T +S  
Sbjct: 842  --------PNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERE-TFSSAE 892

Query: 190  GDKKTDQMVFHLETNSNSESHDKRQSDNI--LCSEDSGFVPVEKTPNLVNSVTSNNCADD 247
            G    D  +  L      +      +D +  L  ++  F  +E     V  V        
Sbjct: 893  GTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLE-----VRKVAETKEKSK 947

Query: 248  ILKTDECSRTSISNCESADSTWQSSLDTNNNSHYQKKRMFSENEENVKRMKTSEQINENI 307
             LKT  C +      + A+   +    ++  S   KK+     EE  K     +++    
Sbjct: 948  HLKTKTCKKVQDGLSDIAEKFLKKD-QSDETSEDDKKQSKKGTEEKKKPSDFKKKV---- 1002

Query: 308  CVSLERQTAFLEQVRHLIQQEIYSINYELFDKKLKELNQRIGKTECRNKHEGIADKLLAK 367
             + +E+Q          + +     +   F K +K++    G T+   K + I DK   K
Sbjct: 1003 -IKMEQQYESSSDGTEKLPEREEICH---FPKGIKQIKN--GTTDGEKKSKKIRDKTSKK 1056

Query: 368  IAKLQRRIKTVLLFQRNC-LKPNMLSSNGASKVANSEAMILDKNL----ESVNSPIEKSS 422
              +L    +       +C    +  S NGA         +L K+     +  +S  EK S
Sbjct: 1057 KDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKKRCKLLGKSSRKRQDCSSSDTEKYS 1116

Query: 423  VNYEPSNPSEKGSKKINLSSDQNKSVSESNNDDVMLISVESPNLTTPITSNPTDTRKITS 482
            +  +  N S+K  K+I L   +N S   +  +      ++S + ++    +  D +K   
Sbjct: 1117 MKEDGCNSSDKRLKRIELRERRNLSSKRNTKE------IQSGSSSSDAEESSEDNKK--K 1168

Query: 483  GNSSNSPNAEVMAVQKKLDSIIDLTKEGLSNCNTESPVSPLE-----SHSKAASNSKETT 537
               ++S    V+  +KK +S+   TK   ++  T S  S +E     S  + +S+ ++  
Sbjct: 1169 KQRTSSKKKAVIVKEKKRNSLRTSTKRKQADI-TSSSSSDIEDDDQNSIGEGSSDEQKIK 1227

Query: 538  PLAQNAV 544
            P+ +N V
Sbjct: 1228 PVTENLV 1234



 Score = 31.2 bits (69), Expect = 3.3
 Identities = 70/392 (17%), Positives = 138/392 (35%), Gaps = 23/392 (5%)

Query: 66   KCSPSENGASSLDSNKNSISEKSKVFSQNCIKPVEEIVHSETKLEQVVCSYQKPSRTTES 125
            K S      SS D+ K S+ E     S   +K +E         ++     Q  S ++++
Sbjct: 1099 KSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSDA 1158

Query: 126  PSRVFTEEAKDSLNTSENDSEHQTNVTRSLFEHEGACSLKSSCCPPSVLSGVVQMPESTV 185
                  E ++D+    +  S  +  V   + + +   SL++S           +  ++ +
Sbjct: 1159 E-----ESSEDNKKKKQRTSSKKKAV---IVKEKKRNSLRTS----------TKRKQADI 1200

Query: 186  TSTVGDKKTDQMVFHLETNSNSESHDKRQSDNILCSEDSGFVPVEKTPNLVNSV--TSNN 243
            TS+      D     +   S+ E   K  ++N++ S  +GF        L  SV  T ++
Sbjct: 1201 TSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDD 1260

Query: 244  CADDILKTDECSRTSISNCESADSTWQSSLDTNNNSHYQKKRMFSENEENVKRMKTSEQI 303
              DD    +  ++  +     A+ +      +++     KKR   +NEEN    +   Q+
Sbjct: 1261 DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQV 1320

Query: 304  NENICVSLERQTAFLEQVRHLIQQEIYSINYELFDKKLKELNQRIGKTECRNKHEGIADK 363
            N       E       + R L  +   S      +KK K    +  K   R K   ++ +
Sbjct: 1321 NSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRK---VSSE 1377

Query: 364  LLAKIAKLQRRIKTVLLFQRNCLKPNMLSSNGASKVANSEAMILDKNLESVNSPIEKSSV 423
                    +  +   +    +  +P   S+  A    N  +    K    +    + SS 
Sbjct: 1378 DSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSE 1437

Query: 424  NYEPSNPSEKGSKKINLSSDQNKSVSESNNDD 455
            N   S   E+  ++     ++ +   E  NDD
Sbjct: 1438 NKSNSEEEEEEKEEEEEEEEEEEEEEEDENDD 1469


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 98/517 (18%), Positives = 206/517 (39%), Gaps = 26/517 (5%)

Query: 44   SNVPSGNQSFSPSVITRTTEITKCSPSENGASSLDSNKNSISEKSKVFSQNCIKPVEEIV 103
            S+  S +   S S  + +++ +  S S + + S DS+ +S S  SK  S    K   +  
Sbjct: 578  SDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSS---KSESDSS 634

Query: 104  HSETKLEQVVCSYQKPSRTTESPSRVFTEEAKDSLNTSEN-DSEHQTNVTRSLFEHEGAC 162
             S++K +    +    S  ++S     +  + DS ++S++ DS   ++ + S    + + 
Sbjct: 635  DSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSD 694

Query: 163  SLKSSCCPPSVLSGVVQMPESTVTSTVGDKKTDQMVFH--------------LETNSNSE 208
            S  SS    S  S      +S+ +S      +D                    +++++S+
Sbjct: 695  SSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSD 754

Query: 209  SHDKRQSDNILCSEDSGFVPVEKTPNLVNSVTSNNCADDILKTDECSRTSISN-CESADS 267
            S D   S N   S DS       + +  NS  SN+ ++    +D  + +  SN  +S+DS
Sbjct: 755  SSDSSDSSNSSDSSDSS--DSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDS 812

Query: 268  TWQSSLDTNNNSHYQKKRMFSENEENVKRMKTSEQINENICVSLERQTAFLEQVRHLIQQ 327
            +  S  D++N+S        S++  +     +S+  + +   S  R  +           
Sbjct: 813  SDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSD 872

Query: 328  EIYSINYELFDKKLKELNQRIGKTECRNKHEGIADKLLAKIAKLQRRIKTVLLFQRNCLK 387
               S +        +  N         +     +D   +  +       +    + +   
Sbjct: 873  SSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDS--SNSSDSSDSSNSSDSSESSNSS 930

Query: 388  PNMLSSNGASKVANSEAMILDKNLESVNSPIEKSSVNYEPSNPSEKG-SKKINLSSDQNK 446
             N  SS+ ++   +S++     + +S NS    +S +   SN S+   S   + SSD + 
Sbjct: 931  DNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSD 990

Query: 447  SVSESNNDDVMLISVESPNLTTPITSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDL 506
            S   S++ D    S  S +  +  +SN +D+    S +SSNS ++   +         D 
Sbjct: 991  SSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSS--NSSDSSNSSDSSDSSDSSDSSDSSDS 1048

Query: 507  TKEGLSNCNTESPVSPLESHSKAASNSKETTPLAQNA 543
            +    S+ +++S  S   S S  +S+S +++  ++++
Sbjct: 1049 SDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESS 1085



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 57/282 (20%), Positives = 113/282 (40%), Gaps = 15/282 (5%)

Query: 30   NKSRNVEALKTAIGSNVPSGNQSFSPSVITRTTEITKCSPSENGASSLDSNKNSISEKSK 89
            + S + ++  ++  S+    + S   S  + + + +  S S + ++S DS+ +S S  S 
Sbjct: 754  DSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSS 813

Query: 90   VFSQNCIKPVEEIVHSETKLEQVVCSYQKPSRTTESPSRVFTEEAKDSLNTSEN-DSEHQ 148
              S +      +  +S    +    S    S  +   S   +    DS N+S++ DS   
Sbjct: 814  DSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDS 873

Query: 149  TNVTRSLFEHEGACSLKSSCCPPSVLSGVVQMPESTVTSTVGDKKTDQMVFHLETNSNSE 208
            +N + S    +   S  SS    S  S      +S+ +S   D           +NS+  
Sbjct: 874  SNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDS----------SNSSDS 923

Query: 209  SHDKRQSDNILCSEDSGFVPVEKTPNLVNSVTSNNCADDILKTDECSRTSISNCESADST 268
            S     SDN   S+ S       + +  NS  S+N +D    +D     S  + +S++S+
Sbjct: 924  SESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSS 983

Query: 269  WQS----SLDTNNNSHYQKKRMFSENEENVKRMKTSEQINEN 306
              S    S D++++S        S++ ++     +S+  N +
Sbjct: 984  DSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSS 1025



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 58/264 (21%), Positives = 115/264 (43%), Gaps = 15/264 (5%)

Query: 30   NKSRNVEALKTAIGSNVPSGNQSFSPSVITRTTEITKCSPSENGASSLDSNKNSISEKSK 89
            N S + ++  ++ GS+  S N+S S S  + +++ +  S S + + S DSN++S S  S 
Sbjct: 837  NSSDSSDSSDSSDGSDSDSSNRSDS-SNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSS 895

Query: 90   VFSQNCIKPVEEIVHSETKLEQVVCSYQKPS-------RTTESPSRVFTEEAKDSLNTSE 142
              S +      +  +S    +    S    S        +++S +   + ++ DS N+S+
Sbjct: 896  DSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSD 955

Query: 143  N-DSEHQTNVTRSLFEHEGACSLKSSCCPPSVLSGVVQMPESTVTSTVGDKK-----TDQ 196
            + +S   +N + S   +    S  S+    S  S      +S+ +S   D       +D 
Sbjct: 956  SSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1015

Query: 197  MVFHLETNSNSESHDKRQSDNILCSEDSGFVPVEKTPNLVNSVTSNNCADDILKTDEC-S 255
                  +NS+  S+    SD+   S+ S       + +  NS  S++ +D    +D   S
Sbjct: 1016 SNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDS 1075

Query: 256  RTSISNCESADSTWQSSLDTNNNS 279
              S  + ES+DS+  S+   +++S
Sbjct: 1076 SDSSDSSESSDSSDSSNSSDSSDS 1099



 Score = 39.3 bits (90), Expect = 0.012
 Identities = 60/286 (20%), Positives = 114/286 (39%), Gaps = 14/286 (4%)

Query: 30   NKSRNVEALKTAIGSNVPSGNQSFSPSVITRTTEITKCSPSENGASSLDSNKNSISEKSK 89
            N S N      +  S+  S +   S S  +  ++ +  S S N + S DS+ +S S  S 
Sbjct: 786  NDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS 845

Query: 90   VFSQNCIKPVEEIVHSETKLEQVVCSYQKPSR----TTESPSRVFTEEAKDSLNTSENDS 145
              S            S    +    S    S     +++S     + ++ DS N+S++DS
Sbjct: 846  DSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDS 905

Query: 146  EHQTNVTRSLFEHEGACSLKSSCCPP----SVLSGVVQMPESTVTSTVGDKKTDQMVFHL 201
               +N + S      + S +SS        S  S      +S+ +S   D        + 
Sbjct: 906  SDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNS 965

Query: 202  ----ETNSNSESHDKRQSDNILCSEDSGFVPVEKTPNLVNSVTSNNCADDILKTDECSRT 257
                ++NS+  S     SD+   S+ S       + N  +S  S++ +D    +D  + +
Sbjct: 966  SDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSS 1025

Query: 258  SISN-CESADSTWQS-SLDTNNNSHYQKKRMFSENEENVKRMKTSE 301
              SN  +S+DS+  S S D++++S        S++ ++     +S+
Sbjct: 1026 DSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1071



 Score = 38.5 bits (88), Expect = 0.021
 Identities = 53/277 (19%), Positives = 113/277 (40%), Gaps = 12/277 (4%)

Query: 30   NKSRNVEALKTAIGSNVPSGNQSFSPSVITRTTEITKCSPSENGASSLDSNKNSISEKSK 89
            + S + ++  ++  SN    + S   S  + +++ +  S S N + S DS+ +S S  S 
Sbjct: 1014 DSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1073

Query: 90   VFSQNCIKPVEEIVHSETKLEQVVCSYQKPSRTTESPSRVFTEEAKDSLNTSEN-DSEHQ 148
              S +          S++            S +++S     + ++ DS ++S++ DS + 
Sbjct: 1074 DSSDS----------SDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1123

Query: 149  TNVTRSLFEHEGACSLKSSCCPPSVLSGVVQMPESTVTSTVGDKKTDQMVFHLETNSNSE 208
            ++ + S    + + S  SS    S  S        +  S+     +D       +NS+  
Sbjct: 1124 SDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDS 1183

Query: 209  SHDKRQSDNILCSEDSGFVPVEKTPNLVNSVTSNNCADDILKTDEC-SRTSISNCESADS 267
            S     SD+   S+ S       + +  +S  S++ +D    +D   S  S  + +S+DS
Sbjct: 1184 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDS 1243

Query: 268  TWQSSLDTNNNSHYQKKRMFSENEENVKRMKTSEQIN 304
            +  S+   +++S          N+E+  + K+    N
Sbjct: 1244 SDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNN 1280



 Score = 37.4 bits (85), Expect = 0.046
 Identities = 54/281 (19%), Positives = 110/281 (39%), Gaps = 19/281 (6%)

Query: 30   NKSRNVEALKTAIGSNVPSGNQSFSPSVITRTTEITKCSPSENGASSLDSNKNSISEKSK 89
            + S + ++  ++  SN    N S + S  + ++  +  S S + + S DS+ +  S  S 
Sbjct: 766  DSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSD 825

Query: 90   VFSQNCIKPVEEIVHSETKLEQVVCSYQKPSRTTESPSRVFTEEAKDSLNTSEN----DS 145
              + +          S    +    S    S  ++S +   + ++ DS N+S++    DS
Sbjct: 826  SSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDS 885

Query: 146  EHQTNVTRSLFEHEGACSLKSSCCPPSVLSGVVQMPESTVTSTVGDKKTDQMVFHLETNS 205
               +N + S      + S  S     S  S      +S+ +S   D          ++++
Sbjct: 886  NESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSS-----DSSN 940

Query: 206  NSESHDKRQSDNILCSEDSGFVPVEKTPNLVNSVTSNNCADDILKTDECSRTSISNCESA 265
            +S+S D   S N   S +S       + N  +S  SN+           S  S  + +S+
Sbjct: 941  SSDSSDSSDSSNSSDSSNSS-----DSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSS 995

Query: 266  DSTWQSSLDTNNNSHYQKKRMFSENEENVKRMKTSEQINEN 306
            DS+     D++N+S        S++  +     +S+  N +
Sbjct: 996  DSS-----DSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSS 1031



 Score = 37.0 bits (84), Expect = 0.060
 Identities = 54/262 (20%), Positives = 102/262 (38%), Gaps = 8/262 (3%)

Query: 32  SRNVEALKTAIGSNVPSGNQSFSPSVITRTTEITKCSPSENGASSLDSNKNSISEKSKVF 91
           S + ++  ++  S+    + S S S     +  +  S S +  SS  SN +  S+ S   
Sbjct: 552 SDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSS 611

Query: 92  SQNCIKPVEEIVHSETKLEQVVCSYQKPSRTTESPSRVFTEEAKDSLNTSENDSEHQTNV 151
             +      +     +K E         S +++S S      +  S N+  +DS + +N 
Sbjct: 612 DSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNS------SDSSDNSDSSDSSNSSNS 665

Query: 152 TRSLFEHEGACSLKSSCCPPSVLSGVVQMPESTVTSTVGDKKTDQMVFHLETNSNSESHD 211
           + S    + + S  SS    S  S       ++  S+     +D        +SNS S D
Sbjct: 666 SDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSD 725

Query: 212 KRQSDNILCSEDSGFVPVEKTPNLVNSVTSNNCADDILKTDECSRTSISNCESADSTWQS 271
              S++   S+ S       + +  NS  S++ +D    +D  S  S  + +S+DS+  S
Sbjct: 726 SDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSD--SSDSSDSSDSSDSSNSS 783

Query: 272 SLDTNNNSHYQKKRMFSENEEN 293
             + ++NS        S +  N
Sbjct: 784 DSNDSSNSSDSSDSSNSSDSSN 805



 Score = 36.2 bits (82), Expect = 0.10
 Identities = 56/251 (22%), Positives = 105/251 (41%), Gaps = 24/251 (9%)

Query: 30   NKSRNVEALKTAIGSNVPSGNQSFSPSVITRTTEITKCSPSENGASSLDSNKNSISEKSK 89
            N S + ++  ++  S+    + S   S  + +++ +  S S + + S DS+ +S S  S 
Sbjct: 1056 NSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS 1115

Query: 90   VFSQNCIKPVEEIVHSETKLEQVVCSYQKPSRTTESPSRVFTEEAKDSLNTSEN-DSEHQ 148
              S +     +    S++       +    S ++ES     + ++ DS ++S++ DS   
Sbjct: 1116 DSSDSS-NSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDS 1174

Query: 149  TNVTRSLFEHEGACSLKSSCCPPSVLSGVVQMPESTVTSTVGDKKTDQMVFHLETNSNSE 208
            ++ + S    + + S  SS    S  S      +S+ +S   D          +++ +S+
Sbjct: 1175 SDSSNSSDSSDSSDSSDSSDSSDSSDSS-----DSSDSSDSSDSSDSS-----DSSDSSD 1224

Query: 209  SHDKRQSDNILCSEDSGFVPVEKTPNLVNSVTSNNCADDILKTDECSRTSISNCESADST 268
            S D   S+    S DS            +S  S+N +D    +D    TS SN ES DS 
Sbjct: 1225 SSDSSDSNESSDSSDSS-----------DSSDSSNSSDSSDSSDSSDSTSDSNDES-DSQ 1272

Query: 269  WQSSLDTNNNS 279
             +S    NN S
Sbjct: 1273 SKSGNGNNNGS 1283



 Score = 34.3 bits (77), Expect = 0.39
 Identities = 36/151 (23%), Positives = 69/151 (45%), Gaps = 5/151 (3%)

Query: 389 NMLSSNGASKVANSEAMILDKNLESVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNKSV 448
           N   SNG     N +    DK+           S + + SN S+      + SSD N S 
Sbjct: 522 NNSDSNGNGNNGNDDN---DKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSS 578

Query: 449 SESNNDDVMLISVESPNLTTPITSNPTDTRKIT-SGNSSNSPNAEVMAVQKKLDSIIDLT 507
              ++D     S +S +  +  +S+ +D+   + S +SS+S +++  + + + DS    +
Sbjct: 579 DSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDS 638

Query: 508 KEGLSNCN-TESPVSPLESHSKAASNSKETT 537
           K   S+ N ++S  +   S S  +SNS +++
Sbjct: 639 KSDSSDSNSSDSSDNSDSSDSSNSSNSSDSS 669



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 35/141 (24%), Positives = 65/141 (46%), Gaps = 4/141 (2%)

Query: 393 SNGASKVANSEAMILDKNLESVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNKSVSESN 452
           SN +S   +S++   D + +S +S    SS + + S+ S+      +  S  + S SES+
Sbjct: 574 SNSSSDSDSSDSDSSDSS-DSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESD 632

Query: 453 NDDVMLISVESPNLTTPITSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDLTKEGLS 512
           + D    S  S + ++  + N   +    S NSSNS ++   +      S  D +    S
Sbjct: 633 SSDSDSKSDSSDSNSSDSSDNSDSS---DSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDS 689

Query: 513 NCNTESPVSPLESHSKAASNS 533
           + +++S  S   S S  +S+S
Sbjct: 690 SDSSDSSNSSESSDSSDSSDS 710



 Score = 30.4 bits (67), Expect = 5.6
 Identities = 34/146 (23%), Positives = 65/146 (44%), Gaps = 9/146 (6%)

Query: 392  SSNGASKVANSEAMILDKNLESVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNKSVSES 451
            SSN +    +S++     + +S +S     S +   S+ S   S     SSD + S   S
Sbjct: 1015 SSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD----SSDSSDSSDSS 1070

Query: 452  NNDDVMLISVESPNLTTPITSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDLTKEGL 511
            ++ D    S  S +  +  +SN +D     S +SS+S ++   +         D +    
Sbjct: 1071 DSSDSSDSSDSSESSDSSDSSNSSD-----SSDSSDSSDSSDSSDSSDSSDSSDSSNSSD 1125

Query: 512  SNCNTESPVSPLESHSKAASNSKETT 537
            S+ +++S  S   S+S  +S+S E++
Sbjct: 1126 SSDSSDSSDSSDSSNSSDSSDSSESS 1151


>gi|161016767 mucin 21 [Homo sapiens]
          Length = 566

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 53/254 (20%), Positives = 102/254 (40%), Gaps = 18/254 (7%)

Query: 34  NVEALKTAIGSNVPSGNQSFSPSVITRTTEITKCSPSENGASSLDSNKNSISEKSKVFSQ 93
           N E+  T+ G++  + ++S +PS    T   +  S + +GAS+  ++ +S +      + 
Sbjct: 107 NSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEASTAT 166

Query: 94  NCIKPVEEIVHSETKLEQVVCSYQKPSRTTESPSRVFTEEAKDSLN----TSENDSEHQT 149
           N          S     +      + S  T S S   +  A  + N    T+ N +   T
Sbjct: 167 NSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTAT 226

Query: 150 NVTRSLFEHEGACSLKSSCCPPSVLSGVVQMPESTVTS----TVGDKKTDQMVFHLETNS 205
           N   S      + +  S    PS  +G     ES+ TS    T  + ++  +   + T +
Sbjct: 227 NSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVT 286

Query: 206 NSESHDKRQSDNILCSEDSGFVPVEKTPNLVNSVTSNNCADDILKTDECSRTSISNCESA 265
           NSES       N   + +S       T +  N+ T+++ +     T     ++ +N ES+
Sbjct: 287 NSESSTPSSGANTATNSES-----STTSSGANTATNSDSS-----TTSSGASTATNSESS 336

Query: 266 DSTWQSSLDTNNNS 279
            ++  +S  TN+ S
Sbjct: 337 TTSSGASTATNSES 350



 Score = 33.1 bits (74), Expect = 0.87
 Identities = 33/146 (22%), Positives = 56/146 (38%), Gaps = 11/146 (7%)

Query: 392 SSNGASKVANSEAMILDKNLESVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNKSVSES 451
           +S+GA    NSE+  +   + +V         N E S PS   +   N  S    S + +
Sbjct: 263 TSSGAGTATNSESSTVSSGISTV--------TNSESSTPSSGANTATNSESSTTSSGANT 314

Query: 452 NNDDVMLISVESPNLTTPITSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDLTKEGL 511
             +     +    +  T   S+ T +   T+ NS +S  +         +S    T  G 
Sbjct: 315 ATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSS--GASTATNSGSSTTSSGT 372

Query: 512 SNCNTESPVSPLESHSKAASNSKETT 537
           S   T S  S + S +  A+ S+ +T
Sbjct: 373 STA-TNSESSTVSSGASTATTSESST 397


>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis
           critical region 1 [Homo sapiens]
          Length = 1400

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 98/548 (17%), Positives = 189/548 (34%), Gaps = 68/548 (12%)

Query: 56  SVITRTTEITKCSPSENGASSLDSNKNSISEKSKVFSQNCIKPVEEIVHSETKLEQVVCS 115
           S +TR ++ T   P E   S+LD    S  + +  F  +     ++   S +  E++  +
Sbjct: 238 STVTRKSDKTG-RPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQ--KSTSFPEKITAA 294

Query: 116 YQKPSRTTESPSRVFTEEAKDSLNTSENDSEHQTNVTRSLFEHEGACSLKSSCCPPSVLS 175
            +   +TT +P    +E+ +DS  T  +D +  T  T+++ E   A  L  S   P+   
Sbjct: 295 SKTTYKTTGTPEE--SEKTEDSRTTVASD-KLLTKTTKNIQETISANELTQSLAEPTEHG 351

Query: 176 GVVQMPESTVTSTVGDKKTDQMVFHLETNSNSESHDKRQ----------------SDNIL 219
           G      +T +     +  ++      T S +E  + R+                +  + 
Sbjct: 352 GRTANENNTPSPAEPTENRERTANENTTLSPAEPTENRERTANENTAPFPAGPTENREMT 411

Query: 220 CSEDSGFVPVEKTPNLVNSVTSNNCADDILKTDECSRTSISNCESADSTWQSSLDTNNNS 279
            +E++   P E T +   +   N        T+   RT+  N   + +      +    +
Sbjct: 412 ANENTTLFPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPA---EPTEHGERT 468

Query: 280 HYQKKRMFSENEENVKRMKTSEQINENICVSLERQTAFLEQVRHLIQQEIYSINYELFDK 339
            +   +  S + E+ +  + +   NEN   S    T   E+  +                
Sbjct: 469 PFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERTANE--------------- 513

Query: 340 KLKELNQRIGKTECRNKHEGIADKL-LAKIAKLQRRIKTVLLFQRNCLKPNMLSSNGA-- 396
                    G TE  N+     +K  L+ +   + R  T    ++    P   + NG   
Sbjct: 514 --NTTPSPAGPTE--NRETTANEKTTLSPVEPTENRETTAN--EKTTPSPAEPTENGQRT 567

Query: 397 ----SKVANSEAMILDKNLESVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNKSVSESN 452
                K  +S A   +       +P+   +    P+ P+E   +  N  +  + +    N
Sbjct: 568 PFANEKTTSSSA---EPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTEN 624

Query: 453 NDDVMLISVESPNLTTPITSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDLTKEGLS 512
            D   L + +    TTP  + PT+       N   +P A         +      +  L+
Sbjct: 625 GDRTPLANEK----TTPSLAEPTE-------NGQRTPFANEKTTSSSAEPTEHEERTPLA 673

Query: 513 NCNTE-SPVSPLESHSKAASNSKETTPLAQNAVQVPESFEHLPPLPEPPAPLPELVDKTR 571
           N NT  SP  P E+  + A+ +   +P      +   + E     P  P    E     +
Sbjct: 674 NENTTPSPAEPTENRERTANENTTPSPAGPTENREMTANEKTTLFPAEPTENRERTANEK 733

Query: 572 DTLPPQKP 579
            T  P +P
Sbjct: 734 TTSSPAEP 741



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 50/218 (22%), Positives = 81/218 (37%), Gaps = 23/218 (10%)

Query: 384 NCLKPNMLSSNGASKVANSEAMILDKNLESVNSPIEKS-SVNYEPSNPSEKGSKKI-NLS 441
           NC K    S+ G S V            +    P+EKS S   + S  S K +    N  
Sbjct: 229 NCRK----STTGKSTVTRKS--------DKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSG 276

Query: 442 SDQNKSVSESNNDDVMLISVESPNLT-TPITSNPTDTRKITSGNS-----SNSPNAEVMA 495
           + Q K  S S  + +   S  +   T TP  S  T+  + T  +      +     E ++
Sbjct: 277 NSQTKQKSTSFPEKITAASKTTYKTTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETIS 336

Query: 496 VQKKLDSIIDLTKEG---LSNCNTESPVSPLESHSKAASNSKETTPLAQNAVQVPESFEH 552
             +   S+ + T+ G    +  NT SP  P E+  + A+ +   +P      +   + E+
Sbjct: 337 ANELTQSLAEPTEHGGRTANENNTPSPAEPTENRERTANENTTLSPAEPTENRERTANEN 396

Query: 553 LPPLPEPPAPLPELVDKTRDTLPPQKPELKVKRVFRPN 590
             P P  P    E+      TL P +P    +R    N
Sbjct: 397 TAPFPAGPTENREMTANENTTLFPAEPTEHGERTANEN 434



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 34/154 (22%), Positives = 55/154 (35%), Gaps = 12/154 (7%)

Query: 427 PSNPSEKGSKKINLSSDQNKSVSESNNDDVMLISVESPNLTTPITSNPTDTRKITSGNSS 486
           P+ P+E   +  N ++  + +    N D   L + +    TTP  + PT+       N  
Sbjct: 799 PAEPTENRERTANENTTPSPAQPTENGDRTPLANEK----TTPSLAEPTE-------NGK 847

Query: 487 NSPNAEVMAVQKKLDSIIDLTKEGLSNCNT-ESPVSPLESHSKAASNSKETTPLAQNAVQ 545
            +P A         +      +  L+N NT  SP  P E+  + A+      P      +
Sbjct: 848 RTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENR 907

Query: 546 VPESFEHLPPLPEPPAPLPELVDKTRDTLPPQKP 579
              + E   P P  P    E       TL P +P
Sbjct: 908 ESTANEKTTPFPAEPTENREWTANENTTLSPAEP 941



 Score = 37.4 bits (85), Expect = 0.046
 Identities = 36/160 (22%), Positives = 65/160 (40%), Gaps = 21/160 (13%)

Query: 416 SPIEKSSVNYEPSNPSEKGSKKINLSSDQNKSVSESNNDDVMLISVESPNLTTPITSNPT 475
           +P+   +    P+ P+E   +  N ++  + +    N +      + +   TT   + PT
Sbjct: 670 TPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRE------MTANEKTTLFPAEPT 723

Query: 476 DTRKITSGNSSNSPNAEV--------MAVQKKLDSIIDLTKEG----LSNCNTE-SPVSP 522
           + R+ T+   + S  AE          A +K   S  + T+ G    L+N NT  SP  P
Sbjct: 724 ENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAGP 783

Query: 523 LESHSKAASNSKETTPLAQNAVQVPESFEHLPPLPEPPAP 562
            E+  + A  +++TTP      +  E   +    P P  P
Sbjct: 784 TENRERTA--NEKTTPFPAEPTENRERTANENTTPSPAQP 821


>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
            sapiens]
          Length = 3969

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 104/516 (20%), Positives = 184/516 (35%), Gaps = 75/516 (14%)

Query: 133  EAKDSLNTSENDSEHQTNVTRSLFEHEGACSLKS--------SCCPPSV--LSGVVQMPE 182
            +  D L+TS+ D  +  N TR++    G   L S         C  P +  L GV    E
Sbjct: 2666 DGADDLSTSDEDDLYYYNFTRTVISSGGEERLASHNLFREEEQCDLPKISQLDGVDDGTE 2725

Query: 183  STVTSTVGDKKTDQMVFHLETNSNSESHDKRQSDNILCSEDSGFVPVEKTPNLVNSVTSN 242
            S  + T   +K+ Q+    + N      +  + D     ED+G    EK     +SV   
Sbjct: 2726 SDTSVTATTRKSSQIP---KRNGKENGTENLKIDR---PEDAG----EKEHVTKSSVGHK 2775

Query: 243  NCADDILKTDECSRTSISNCESADS--TWQSSLDTNNNSH----YQKKRMFSENEENVKR 296
            N      K D C   S    +  DS     SSL+++   H      K  + + N E +K 
Sbjct: 2776 NEP----KMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDTYNTELLK- 2830

Query: 297  MKTSEQINENICVSLERQTAFLEQVRHLIQQEIYSINYELFDKKLKELNQRIGKTECRNK 356
               S+  N + C ++         +++    +    + E    +L  L + +G    R K
Sbjct: 2831 -SDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPESSSSELLNLGEGLGLDSNREK 2889

Query: 357  HEGIADKLLAKIAKLQRRIKTVLLFQRNCLKPNMLSSNGASKVANSEAMILDKNLESVNS 416
              G+ +                 +F +       + S+ +S ++  E   L   L S  S
Sbjct: 2890 DMGLFE-----------------VFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLS 2932

Query: 417  PIEKSSVNYEPSNP------SEKGSKKINLSSDQNKSVSESNNDDVMLISVESP---NLT 467
             +   S      NP      S+ G K++ ++    KSV+ S +D  +L     P      
Sbjct: 2933 VLTTRSPTVPSQNPSRLAVISDSGEKRVTIT---EKSVASSESDPALLSPGVDPTPEGHM 2989

Query: 468  TP------------ITSNPTDTRKITSGNSSN-SPNAEVMAVQKKLDSIIDLTKEGLSNC 514
            TP            I+S P  + +   GN+ + + N+    +Q  +   + +  +     
Sbjct: 2990 TPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPN 3049

Query: 515  NTESPVSPLESHSKAASNSKETTPLAQNAVQVPESFEHLPPLPEPPAPLPELVDKTRDTL 574
            +T+SP     S++   +      P  +  + V ++ + L  L   P  + + +  T    
Sbjct: 3050 STDSPGPSQISNAAVQTTPPHLKPATEKLIVVNQNMQPLYVLQTLPNGVTQKIQLTSSVS 3109

Query: 575  PPQKPELKVKRVFRPNGIALTWNITKINPKCAPVES 610
                       V  P G  LT   T +NP     +S
Sbjct: 3110 STPSVMETNTSVLGPMGGGLTLT-TGLNPSLPTSQS 3144



 Score = 38.5 bits (88), Expect = 0.021
 Identities = 60/246 (24%), Positives = 101/246 (41%), Gaps = 27/246 (10%)

Query: 342 KELNQRIGKTECRNKHEGIADKLLAKIAKLQ-RRIKTVLLFQRNCLKPNMLSSNGASKVA 400
           K  +  I K   +   +G   K+  + A+LQ R++KT +   R  + P ++S+  +  + 
Sbjct: 365 KRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMP-VVSAISSRIIK 423

Query: 401 NSEAMILDKNLESVNSPIE----KSSVNYEPSNPSEKGSKKINLSSDQNKSVSESNNDDV 456
                I D   E  + PI+    +S+ N   S PS   S+K + +S  +  +S  ++   
Sbjct: 424 TPRRFIED---EDYDPPIKIARLESTPNSRFSAPSCGSSEKSSAASQHSSQMSSDSSRS- 479

Query: 457 MLISVESPNLTTPITSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDLTKEGLSNCNT 516
                 SP++ T   S  ++  ++     S++P      V   L   I  + E  SN   
Sbjct: 480 -----SSPSVDTSTDSQASEEIQVLPEERSDTPE-----VHPPLP--ISQSPENESNDRR 527

Query: 517 ESPVSPLESHSKAASNSKETTPLAQNAVQVPESFEHLPPLPEPPAPL---PELVDKTRDT 573
               S  E    + +  K +T   Q+A Q   S    PPL  PP PL     + D T   
Sbjct: 528 SRRYSVSERSFGSRTTKKLST--LQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWL 585

Query: 574 LPPQKP 579
           +PP  P
Sbjct: 586 MPPTIP 591


>gi|15559211 RE1-silencing transcription factor [Homo sapiens]
          Length = 1097

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 50/184 (27%), Positives = 84/184 (45%), Gaps = 28/184 (15%)

Query: 393  SNGASKVANSEAMILDKNLESV-NSPIEKSSVNYE----PSNPSEKGSKKINLSSDQNKS 447
            SN  S+ A  E ++++  L  V +S + K SV+ E    PS P  K + +   S DQ   
Sbjct: 824  SNMQSERARKEQVLIEVGLVPVKDSWLLKESVSTEDLSPPSPPLPKENLREEASGDQKLL 883

Query: 448  VSESNNDDVML--ISVESPNLTTP-ITSNPTDTRKITS-GNSSNSPNAEVMAVQKKLDSI 503
             +   N +  L  +  E  + + P + +N  ++  I+S G + N+P  E +  + + DSI
Sbjct: 884  NTGEGNKEAPLQKVGAEEADESLPGLAANINESTHISSSGQNLNTPEGETLNGKHQTDSI 943

Query: 504  I--------DLTKEGLSNCNT--ESPVSPL---------ESHSKAASNSKETTPLAQNAV 544
            +          T+E L+  N+  E PVSP+         E+ SK A  S   T  A  + 
Sbjct: 944  VCEMKMDTDQNTRENLTGINSTVEEPVSPMLPPSAVEEREAVSKTALASPPATMAANESQ 1003

Query: 545  QVPE 548
            ++ E
Sbjct: 1004 EIDE 1007


>gi|238624188 diffuse panbronchiolitis critical region 1 protein
           [Homo sapiens]
          Length = 1393

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 107/594 (18%), Positives = 205/594 (34%), Gaps = 87/594 (14%)

Query: 30  NKSRNVEALKTAIGSNVPSGNQSFSPSVITRTTEITKCSPSENGASS----LDSNKNSIS 85
           +K+ +  A  T  G   P  N++ +PS     TE  + + +EN   S     ++ + + +
Sbjct: 411 DKTTSSSAESTEHGERTPLANENTTPSP-AEPTENRERTANENTTPSPAGPTENRETTAN 469

Query: 86  EKSKVFSQNCIKPVEEIVHSETKLEQVVCSYQKPSRTTESPSRV-FTEEAKDSLNTSEND 144
           EK+       + PVE   + ET   +       P+  TE+  R  F  E   S +    +
Sbjct: 470 EKTT------LSPVEPTENRETTANEKTTP--SPAEPTENGQRTPFANEKTTSSSAEPTE 521

Query: 145 SEHQT-----NVTRSLFE----HEGACSLKSSCCPPSVLSGVVQMP---ESTVTSTVGDK 192
              +T     N T S  E     E   + K++  P        + P   E T  S     
Sbjct: 522 HGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPT 581

Query: 193 KTDQMV--FHLETNSNSESHDKRQSDNILCSEDSGFVPVEKTPNLVNSVTSNNCADDILK 250
           +  Q     + +T S+S    + +    L +E++   P E T N   +   N        
Sbjct: 582 ENGQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANENTTPSPAGP 641

Query: 251 TDECSRTSISNC----------------ESADSTWQSSLDTNNNSHYQKKRMFSENEENV 294
           T+    T+                    E   S+     +    + +  ++  S + E  
Sbjct: 642 TENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPT 701

Query: 295 KRMKTSEQINENICVSLERQTAFLEQVRHLIQQEIYSINYELFDKKLKELNQRIGKTECR 354
           +  + +   NEN  +S    T   E+  +   ++      E  + + +  N+    +  +
Sbjct: 702 EHGERTPLANENTTLSPAEPTENRERTAN---EKTTPFPAEPTENRERTANENTTPSPAQ 758

Query: 355 NKHEG-----IADKLLAKIAKLQRRIKTVLLFQRNCLKPNMLSSNGASKVANSEAMILDK 409
               G       +K    +A+     K      R        +S+ A    ++E      
Sbjct: 759 PTENGDRTPLANEKTTPSLAEPTENGK------RTPFANEKTTSSSAEPTEHAE------ 806

Query: 410 NLESVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNKSVSESNNDDVMLISVESPNLTTP 469
                 +P+   +    P+ P+E   +  N  + Q  +    N +        +   TTP
Sbjct: 807 -----RTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENREST------ANEKTTP 855

Query: 470 ITSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDLTKEGLSNCNTESPVSPLESHSKA 529
             + PT+ R+ T+  ++    AE      + + +  L  E      T SP  P E+  + 
Sbjct: 856 FPAEPTENREWTANENTTLSPAE----PTEHEEMTPLANEK----TTLSPAEPTENGERT 907

Query: 530 ASNSKETTPLA----QNAVQVPESFEHLPPLPEPPAPLPELVDKTRDTLPPQKP 579
              +++TTP +    ++  + P + E   P    P    E +   + T  P KP
Sbjct: 908 PFTNEKTTPSSAEPTEHGERTPLANEITTPSRAEPTEHGERIANEKATPSPAKP 961



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 103/553 (18%), Positives = 189/553 (34%), Gaps = 67/553 (12%)

Query: 40  TAIGSNVPSGNQSFSPSVITRTTEITKCSPSENGASSLDSNKNSISEKSKVFSQNCIKPV 99
           T  G    + N + SP+  T   E T  +  +  +SS +S ++   E++ + ++N     
Sbjct: 381 TEHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHG--ERTPLANENTTPSP 438

Query: 100 EEIVHSETKLEQVVCSYQKPSRTTESPSRVFTEEAKDSLNTSENDSEHQTNVTRSLFEHE 159
            E   +    E+       PS    + +R  T   K +L+  E     +T          
Sbjct: 439 AEPTENR---ERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANE------ 489

Query: 160 GACSLKSSCCPPSVLSGVVQMPESTVTSTVGDKKTDQMVFHLETNSNSE--SHDKRQSDN 217
                K++  P        +  E+   +   ++KT        T+S++E   H +R    
Sbjct: 490 -----KTTPSP-------AEPTENGQRTPFANEKT--------TSSSAEPTEHGERTP-- 527

Query: 218 ILCSEDSGFVPVEKTPNLVNSVTSNNCADDILKTDECSRTSISNCESADSTWQSSLDTNN 277
            L +E++   P E T N   +            T+   RT ++N ++  S  + + +   
Sbjct: 528 -LANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPT-ENGQ 585

Query: 278 NSHYQKKRMFSENEENVKRMKTSEQINENICVSLERQTAFLEQVRHLIQQEIYSINYELF 337
            + +  ++  S + E  +  + +   NEN   S    T   E+  +       +   E  
Sbjct: 586 RTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENR 645

Query: 338 DKKLKELNQRIGKTECRNKHEGIADKLLAKIAKLQRRIKTVLLFQRNCLKPNMLSSNGAS 397
           +    E           N+     +K  +  A+           QR        +S+ A 
Sbjct: 646 EMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTEN------GQRTPFANEKTTSSSAE 699

Query: 398 KVANSEAMILDKNLESVNSPIEKSSVNYE----------PSNPSEKGSKKINLSSDQNKS 447
              + E   L  N  +  SP E +  N E          P+ P+E   +  N ++  + +
Sbjct: 700 PTEHGERTPL-ANENTTLSPAEPTE-NRERTANEKTTPFPAEPTENRERTANENTTPSPA 757

Query: 448 VSESNNDDVMLISVESPNLTTPITSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDLT 507
               N D   L + +    TTP  + PT+       N   +P A         +      
Sbjct: 758 QPTENGDRTPLANEK----TTPSLAEPTE-------NGKRTPFANEKTTSSSAEPTEHAE 806

Query: 508 KEGLSNCNT-ESPVSPLESHSKAASNSKETTPLAQNAVQVPESFEHLPPLPEPPAPLPEL 566
           +  L+N NT  SP  P E+  + A+      P      +   + E   P P  P    E 
Sbjct: 807 RTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTANEKTTPFPAEPTENREW 866

Query: 567 VDKTRDTLPPQKP 579
                 TL P +P
Sbjct: 867 TANENTTLSPAEP 879



 Score = 38.9 bits (89), Expect = 0.016
 Identities = 50/218 (22%), Positives = 81/218 (37%), Gaps = 23/218 (10%)

Query: 384 NCLKPNMLSSNGASKVANSEAMILDKNLESVNSPIEKS-SVNYEPSNPSEKGSKKI-NLS 441
           NC K    S+ G S V            +    P+EKS S   + S  S K +    N  
Sbjct: 167 NCRK----STTGKSTVTRKS--------DKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSG 214

Query: 442 SDQNKSVSESNNDDVMLISVESPNLT-TPITSNPTDTRKITSGNS-----SNSPNAEVMA 495
           + Q K  S S  + +   S  +   T TP  S  T+  + T  +      +     E ++
Sbjct: 215 NSQTKQKSTSFPEKITAASKTTYKTTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETIS 274

Query: 496 VQKKLDSIIDLTKEG---LSNCNTESPVSPLESHSKAASNSKETTPLAQNAVQVPESFEH 552
             +   S+ + T+ G    +  NT SP  P E+  + A+ +   +P      +   + E+
Sbjct: 275 ANELTQSLAEPTEHGGRTANENNTPSPAEPTENRERTANENTTLSPAEPIENRERTANEN 334

Query: 553 LPPLPEPPAPLPELVDKTRDTLPPQKPELKVKRVFRPN 590
             P P  P    E+      TL P +P    +R    N
Sbjct: 335 TAPFPAGPTENREMTANENTTLFPAEPTEHGERTANEN 372



 Score = 30.0 bits (66), Expect = 7.4
 Identities = 30/126 (23%), Positives = 48/126 (38%), Gaps = 13/126 (10%)

Query: 467 TTPITSNPTDTRKITSGNSSNSPNAEV--------MAVQKKLDSIIDLTKEG----LSNC 514
           TTP  + PT+  + T+  ++    AE          A  K   S  + T+ G    L+N 
Sbjct: 373 TTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANE 432

Query: 515 NTE-SPVSPLESHSKAASNSKETTPLAQNAVQVPESFEHLPPLPEPPAPLPELVDKTRDT 573
           NT  SP  P E+  + A+ +   +P      +   + E     P  P    E     + T
Sbjct: 433 NTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKTT 492

Query: 574 LPPQKP 579
             P +P
Sbjct: 493 PSPAEP 498


>gi|109637791 transcription factor-like nuclear regulator [Homo
            sapiens]
          Length = 2624

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 38/143 (26%), Positives = 66/143 (46%), Gaps = 13/143 (9%)

Query: 429  NPSEKGSKKINLSSDQNKSVSESNNDDVMLISVESPNLTTPITSNPTDTRKITSGNSSNS 488
            N  E+GS++I ++ ++   + ++   D   IS     L    TS  TDT  + SG++  S
Sbjct: 1289 NFRERGSEEICVTEEKVAELKQTGKTD---ISPRENELEETSTSRQTDTHLMQSGSNDFS 1345

Query: 489  --PNAEVMAVQKKLDSIIDLTKEGLSNCNTESPVSPLESHSKAASNSKETTPLAQNAVQ- 545
              P+ ++  +  ++ S++    E     N+E  VS   SH K +S + E+       +Q 
Sbjct: 1346 AVPSLDIQNISSEVLSMMHTPVE--EKRNSEKEVSSHFSHFKISSQTHESDKTEVQGIQS 1403

Query: 546  --VPESFEHL---PPLPEPPAPL 563
              VPE F  +     LP+   PL
Sbjct: 1404 PDVPEQFSDINLSKSLPQEQKPL 1426


>gi|45237195 Janus kinase and microtubule interacting protein 2
           [Homo sapiens]
          Length = 810

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 57/246 (23%), Positives = 105/246 (42%), Gaps = 39/246 (15%)

Query: 258 SISNCESADSTWQSSLDTNNNSHYQK-KRMFSENEENVKRMKTSEQINENICVSLER--- 313
           ++SN   AD      L + + SH +   ++  E+E +++R+    +  + I  SLE+   
Sbjct: 169 ALSNMIQADKIKAGDLRSEHQSHQEAISKIKWESERDIRRLMDEIKAKDRIIFSLEKELE 228

Query: 314 -QTAFLEQVRHLIQQEIYSINYELFDKKLKELNQRIGKTEC----------------RNK 356
            QT ++++++  +Q+E  +++ +LF  K  E N    K E                 R  
Sbjct: 229 TQTGYVQKLQ--LQKE--ALDEQLFLVKEAECNMSSPKREIPGRAGDGSEHCSSPDLRRN 284

Query: 357 HEGIADKLLAKIAKLQRRIKTVLLFQRNCL-----------KPNMLSSNGASKVANSEAM 405
            + IA+ L A I KL+ R  T+L  +RN L           KP +L  N      N E M
Sbjct: 285 QKRIAE-LNATIRKLEDR-NTLLGDERNELLKRVRETEKQCKP-LLERNKCLAKRNDELM 341

Query: 406 ILDKNLESVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNKSVSESNNDDVMLISVESPN 465
           +  + +E     + K +        S    KK+   +D +++  E   + + L  +E  N
Sbjct: 342 VSLQRMEEKLKAVTKENSEMREKITSHPPLKKLKSLNDLDQANEEQETEFLKLQVIEQQN 401

Query: 466 LTTPIT 471
           +   +T
Sbjct: 402 IIDELT 407


>gi|112799849 tumor protein p53 binding protein, 2 isoform 1 [Homo
           sapiens]
          Length = 1134

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 44/198 (22%), Positives = 81/198 (40%), Gaps = 19/198 (9%)

Query: 393 SNGASKVANSEAMILDKNLESVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNKSVSESN 452
           SN     ++++   L K L +   P++K S   EP  P+    +K+     Q  +++   
Sbjct: 713 SNPYRNQSDADLEALRKKLSNAPRPLKKRSSITEPEGPNGPNIQKLLY---QRTTIAAME 769

Query: 453 NDDVMLISVES-PNLTTPITSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDLTKEGL 511
                 ISV S P+ +  +T++     +I +      P  EV+++  +  S  D+     
Sbjct: 770 T-----ISVPSYPSKSASVTASSESPVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNAST 824

Query: 512 SNCNTESPVSPLESHSKAA--------SNSKETTPLAQNAVQVPESFEHLPPLPEPPAPL 563
            N +  +P   L+   +          +N +E  P A + + V    E  PP P PP P 
Sbjct: 825 ENSDMPAPSPGLDYEPEGVPDNSPNLQNNPEEPNPEAPHVLDV--YLEEYPPYPPPPYPS 882

Query: 564 PELVDKTRDTLPPQKPEL 581
            E      D++  + PE+
Sbjct: 883 GEPEGPGEDSVSMRPPEI 900



 Score = 30.0 bits (66), Expect = 7.4
 Identities = 33/142 (23%), Positives = 56/142 (39%), Gaps = 17/142 (11%)

Query: 441 SSDQNKSVS-ESNNDDVMLISVESPNLTTPITSNPTDTRKITSGNSSNSPNAEVMAVQKK 499
           S+ Q K  S E   + V  +     N   P   +PT      S    N  +A++ A++KK
Sbjct: 671 SNSQGKPGSPEPETEPVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQSDADLEALRKK 730

Query: 500 LDSIIDLTKEGLSNCNTESPVSP--------------LESHSKAA--SNSKETTPLAQNA 543
           L +     K+  S    E P  P              +E+ S  +  S S   T  +++ 
Sbjct: 731 LSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMETISVPSYPSKSASVTASSESP 790

Query: 544 VQVPESFEHLPPLPEPPAPLPE 565
           V++   + H+ P  E  + +PE
Sbjct: 791 VEIQNPYLHVEPEKEVVSLVPE 812


>gi|4885643 tumor protein p53 binding protein, 2 isoform 2 [Homo
           sapiens]
          Length = 1005

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 44/198 (22%), Positives = 81/198 (40%), Gaps = 19/198 (9%)

Query: 393 SNGASKVANSEAMILDKNLESVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNKSVSESN 452
           SN     ++++   L K L +   P++K S   EP  P+    +K+     Q  +++   
Sbjct: 584 SNPYRNQSDADLEALRKKLSNAPRPLKKRSSITEPEGPNGPNIQKLLY---QRTTIAAME 640

Query: 453 NDDVMLISVES-PNLTTPITSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDLTKEGL 511
                 ISV S P+ +  +T++     +I +      P  EV+++  +  S  D+     
Sbjct: 641 T-----ISVPSYPSKSASVTASSESPVEIQNPYLHVEPEKEVVSLVPESLSPEDVGNAST 695

Query: 512 SNCNTESPVSPLESHSKAA--------SNSKETTPLAQNAVQVPESFEHLPPLPEPPAPL 563
            N +  +P   L+   +          +N +E  P A + + V    E  PP P PP P 
Sbjct: 696 ENSDMPAPSPGLDYEPEGVPDNSPNLQNNPEEPNPEAPHVLDV--YLEEYPPYPPPPYPS 753

Query: 564 PELVDKTRDTLPPQKPEL 581
            E      D++  + PE+
Sbjct: 754 GEPEGPGEDSVSMRPPEI 771



 Score = 30.0 bits (66), Expect = 7.4
 Identities = 33/142 (23%), Positives = 56/142 (39%), Gaps = 17/142 (11%)

Query: 441 SSDQNKSVS-ESNNDDVMLISVESPNLTTPITSNPTDTRKITSGNSSNSPNAEVMAVQKK 499
           S+ Q K  S E   + V  +     N   P   +PT      S    N  +A++ A++KK
Sbjct: 542 SNSQGKPGSPEPETEPVSSVQENHENERIPRPLSPTKLLPFLSNPYRNQSDADLEALRKK 601

Query: 500 LDSIIDLTKEGLSNCNTESPVSP--------------LESHSKAA--SNSKETTPLAQNA 543
           L +     K+  S    E P  P              +E+ S  +  S S   T  +++ 
Sbjct: 602 LSNAPRPLKKRSSITEPEGPNGPNIQKLLYQRTTIAAMETISVPSYPSKSASVTASSESP 661

Query: 544 VQVPESFEHLPPLPEPPAPLPE 565
           V++   + H+ P  E  + +PE
Sbjct: 662 VEIQNPYLHVEPEKEVVSLVPE 683


>gi|58535453 CDK5 regulatory subunit associated protein 2 isoform b
            [Homo sapiens]
          Length = 1814

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 66/334 (19%), Positives = 138/334 (41%), Gaps = 80/334 (23%)

Query: 179  QMPESTVTSTVGDKKTDQMVFHLETNSNSESHDKRQSDNILCSEDSGFVPVEKTPNLVNS 238
            + PE + +  + D +T +  F         S D++Q +             EKT  +VNS
Sbjct: 1349 ESPEPSASHALSDYETSEKSFF--------SRDQKQDNE-----------TEKTSVMVNS 1389

Query: 239  VTSNNCADDI-------------LKTDECSRTSISN-----CESADSTWQSSLDTNNNS- 279
             + +   + I             +KT+E  R  +        + + S + S  + +++  
Sbjct: 1390 FSQDLLMEHIQEIRTLRKRLEESIKTNEKLRKQLERQGSEFVQGSTSIFASGSELHSSLT 1449

Query: 280  ---HYQKKRMFSENEENVKRMKTSEQINENICVSLERQTAFLEQVRHLIQQEIYSINYEL 336
               H+ +K+  + N   +K  +  ++ N+ +  SL R+T  LE     +Q+E  S+  E 
Sbjct: 1450 SEIHFLRKQNQALNAMLIKGSRDKQKENDKLRESLSRKTVSLEH----LQREYASVKEE- 1504

Query: 337  FDKKLKELNQRIGKTECRNKHEGIADKLLA--KIAKLQRRIKTVLLFQRNCLKPNMLSSN 394
                  E  Q+ G  + R+  + I +   +  +++++Q  +K         L+  +LS N
Sbjct: 1505 -----NERLQKEGSEKERHNQQLIQEVRCSGQELSRVQEEVK---------LRQQLLSQN 1550

Query: 395  GASKVANSEAMILDKNLESVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNKSVSESNND 454
                         DK L+S+   + K+    +  +   +   K  + SD +  + +S+  
Sbjct: 1551 -------------DKLLQSLRVEL-KAYEKLDEEHRRLRDGDKYPMESDNSFDLFDSSQ- 1595

Query: 455  DVMLISVESPNLTTPITSNPTDTRKITSGNSSNS 488
                ++ +S + T P++ N TD+    SG+S+ S
Sbjct: 1596 ---AVTPKSVSETPPLSGNDTDSLSCDSGSSATS 1626


>gi|190341068 forkhead-associated (FHA) phosphopeptide binding domain
            1 [Homo sapiens]
          Length = 1412

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 69/316 (21%), Positives = 128/316 (40%), Gaps = 29/316 (9%)

Query: 263  ESADSTWQSSLDTNNNSHYQKKRMFSENEENVKRMKTSEQINENICVSLERQTAFLEQVR 322
            E+ +S  +   D  N+   QK+   S      ++ K + +  +     LE +    ++  
Sbjct: 775  EALESEKRKVQDLENHLTQQKEISESNIAYEKRKAKEAMEKEKKKVQDLENRLTKQKEEL 834

Query: 323  HLIQQEIYSINYELFDK-KLKELNQRIGKTECRNKHEGIADKLLAKIAKLQR-RIKTVLL 380
             L +Q+   +N +L D   + E  Q+   TE   K E +A KL   +A+L+  + K +++
Sbjct: 835  ELKEQKEDVLNNKLSDALAMVEETQKTKATESL-KAESLALKLNETLAELETTKTKMIMV 893

Query: 381  FQRNCLKPNMLSSNGASKVANSEAMILDKNLESVNSPIEKSSVNYEPSNPSEKGSKKINL 440
             +R  L+  M+ +             L    ES     E+  + Y+     ++ ++ I  
Sbjct: 894  EERLILQQKMVKA-------------LQDEQESQRHGFEEEIMEYKEQ--IKQHAQTIVS 938

Query: 441  SSDQNKSVSESNNDDVMLISVESPNLTTPITSNPTDTRKITSGNSSNSPNAEVMAVQKKL 500
              ++ + V++ +      I+    N   P    P D        SS    A+ MA +  +
Sbjct: 939  LEEKLQKVTQHHKKIEGEIATLKDNDPAPKEERPQDPLVAPMTESS----AKDMAYEHLI 994

Query: 501  DSIIDLTKEGLSNCNTESPVSP--LESHSKAAS-----NSKETTPLAQNAVQVPESFEHL 553
            D ++   KE LS       +     E+HS+ +      N K+   L QN V V +  + L
Sbjct: 995  DDLLAAQKEILSQQEVIMKLRKDLTEAHSRMSDLRGELNEKQKMELEQNVVLVQQQSKEL 1054

Query: 554  PPLPEPPAPLPELVDK 569
              L E  A +  LV+K
Sbjct: 1055 SVLKEKMAQMSSLVEK 1070


>gi|72256200 B-cell CLL/lymphoma 9 [Homo sapiens]
          Length = 1426

 Score = 39.3 bits (90), Expect = 0.012
 Identities = 39/155 (25%), Positives = 59/155 (38%), Gaps = 15/155 (9%)

Query: 426 EPSNPSEKGSKKINLSSDQNKSVSESNNDDVMLIS-VESPNLTTPITSNPTDTR------ 478
           +P  P++    K   S+D  KS    +    M  S   +P  +TP     T T       
Sbjct: 112 DPGTPNDDSDIKECNSADHIKSQDSQHTPHSMTPSNATAPRSSTPSHGQTTATEPTPAQK 171

Query: 479 ---KITSGNSSNSPNAEVMAVQK-KLDSIIDLTKEGLSNCNTESPVSPLESHSKAASNS- 533
              K+    S+   N    AV K ++++I+    + +SN  TE   +PL +   A  N  
Sbjct: 172 TPAKVVYVFSTEMANKAAEAVLKGQVETIVSFHIQNISNNKTERSTAPLNTQISALRNDP 231

Query: 534 ---KETTPLAQNAVQVPESFEHLPPLPEPPAPLPE 565
               +  P   N  Q       L P P  PAP P+
Sbjct: 232 KPLPQQPPAPANQDQNSSQNTRLQPTPPIPAPAPK 266


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 49/189 (25%), Positives = 77/189 (40%), Gaps = 16/189 (8%)

Query: 399  VANSEAMILDKNLESVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNKSVSESNNDDVML 458
            VANSEA  L       NSP+  S+       P+E  S   +  S+ + +++        +
Sbjct: 1820 VANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTV 1879

Query: 459  ISVESPNL-TTP-ITSNPTDT-----RKITSGNSSNSPNAEVMAVQKKLDSI-IDLTKEG 510
             S E+  L TTP +TS P  T        T+ + S+ P +     +  L SI +  T   
Sbjct: 1880 ASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVA 1939

Query: 511  LSNCNTESPV-----SPLESHSKAASNSKETTPLAQNAVQVPESFEHLPPLPEPPAPLPE 565
             S  NT S       +P+ ++S+A+S+    T     ++  P   E   PL   P     
Sbjct: 1940 SSEINTLSTTLADTRTPVTTYSQASSS---PTTADGTSMPTPAYSEGSTPLTSMPLSTTL 1996

Query: 566  LVDKTRDTL 574
            +V     TL
Sbjct: 1997 VVSSEASTL 2005



 Score = 38.5 bits (88), Expect = 0.021
 Identities = 39/186 (20%), Positives = 73/186 (39%), Gaps = 10/186 (5%)

Query: 399  VANSEAMILDKNLESVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNKSVSESNNDDVML 458
            VANSE   L       N+P   S+    P   +E  S   + SS+ N  ++       M+
Sbjct: 2291 VANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMV 2350

Query: 459  ISVESPNL-------TTPITSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDLTKEGL 511
             S E+  L       +TP+T+        T+ + ++ P +        L S+   T   +
Sbjct: 2351 ASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSEGSTPLTSVPVSTMPVV 2410

Query: 512  SNCNTESPVSPLESHSKAASNSK-ETTPLAQNAVQVPES--FEHLPPLPEPPAPLPELVD 568
            S+  +    +P+++ +   ++++  ++P       +P S   E   PL   P     +V 
Sbjct: 2411 SSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVS 2470

Query: 569  KTRDTL 574
                TL
Sbjct: 2471 SEAGTL 2476



 Score = 37.0 bits (84), Expect = 0.060
 Identities = 40/186 (21%), Positives = 73/186 (39%), Gaps = 10/186 (5%)

Query: 399  VANSEAMILDKNLESVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNKSVSESNNDDVML 458
            VANSEA  L       N+P+  S+    P   +E  S   +  S+ +  ++       M+
Sbjct: 995  VANSEASTLSTTPVDSNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMV 1054

Query: 459  ISVESPNL-------TTPITSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDLTKEGL 511
             S E+  L       +TP+T+    +   T+ + ++ P +        L S+   T+  +
Sbjct: 1055 ASSETSTLSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVV 1114

Query: 512  SNCNTESPVSPLE-SHSKAASNSKETTPLAQNAVQVPES--FEHLPPLPEPPAPLPELVD 568
            S+  +    +P++ S     S    ++P       +P S   E   PL   P     +V 
Sbjct: 1115 SSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTLVVS 1174

Query: 569  KTRDTL 574
               +TL
Sbjct: 1175 SEANTL 1180



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 49/155 (31%), Positives = 69/155 (44%), Gaps = 14/155 (9%)

Query: 399  VANSEAMILDKNLESVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNKSVSESNNDDVML 458
            VANSEA  L       NSP+  S+       P+E  S  I+  S+ + +++        +
Sbjct: 1467 VANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTV 1526

Query: 459  ISVESPNL-TTP-ITSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDLTKEGLSNCNT 516
             S E  +L TTP +TS P  T    S  SS+   A+  ++Q    S      EG S   T
Sbjct: 1527 ASSEINSLSTTPAVTSTPVTT---YSQASSSPTTADGTSMQTSTYS------EG-STPLT 1576

Query: 517  ESPVSPLESHSKAASNSKETTPLAQNAVQVPESFE 551
              PVS +   S  A N+  TTP+  +  QV  S E
Sbjct: 1577 SLPVSTMLVVSSEA-NTLSTTPI-DSKTQVTASTE 1609



 Score = 33.1 bits (74), Expect = 0.87
 Identities = 34/157 (21%), Positives = 58/157 (36%), Gaps = 1/157 (0%)

Query: 399  VANSEAMILDKNLESVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNKSVSESNNDDVML 458
            VA+SEA  L       ++P+  SS        +E  S   + + + +  ++        +
Sbjct: 3470 VASSEASTLSTTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPV 3529

Query: 459  ISVESPNL-TTPITSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDLTKEGLSNCNTE 517
             S E+  L TTP+ SN   T    + +S  +     M +    +    LT   LS+    
Sbjct: 3530 ASSEASTLSTTPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVT 3589

Query: 518  SPVSPLESHSKAASNSKETTPLAQNAVQVPESFEHLP 554
            S  +   S      ++  TT    N+   P     LP
Sbjct: 3590 SSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLP 3626



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 38/191 (19%), Positives = 78/191 (40%), Gaps = 15/191 (7%)

Query: 399  VANSEAMILDKNLESVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNKSVSESNNDDVML 458
            +ANSEA  L       ++P+  S+        +E  S +I+  SD +  ++      + +
Sbjct: 2704 LANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPV 2763

Query: 459  ISVESPNLTT-------PITSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSI-IDLTKEG 510
             S E+  ++T       P+T++   +   T+   ++ P +        L S+ ++ T   
Sbjct: 2764 ASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVA 2823

Query: 511  LSNCNTESPVSPLESHSKAASNSK-ETTPLAQNAVQVP-----ESFEHLPPLPEPPAPLP 564
             S   T S  +P+++ +   +++K  ++P     + VP     E    L  +P    P+ 
Sbjct: 2824 SSEAGTLS-TTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVA 2882

Query: 565  ELVDKTRDTLP 575
                 T  T P
Sbjct: 2883 SSEASTLSTTP 2893



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 36/186 (19%), Positives = 73/186 (39%), Gaps = 10/186 (5%)

Query: 399  VANSEAMILDKNLESVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNKSVSESN------ 452
            VA+ EA  L       NSP+  S+       P+E  S   +  ++    ++         
Sbjct: 1643 VASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPV 1702

Query: 453  -NDDVMLISVESPNLTTPITSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDLTKEGL 511
             +  +  +S    + +TP+T++       T+   ++ PN+        L SI   T   L
Sbjct: 1703 ASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVL 1762

Query: 512  SNCNTESPVSPLESHSKAASNSKET-TPLAQNAVQVPES--FEHLPPLPEPPAPLPELVD 568
            S+  +    +P+++ +   ++++ T +P       +P S   E + PL   P     + +
Sbjct: 1763 SSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVAN 1822

Query: 569  KTRDTL 574
                TL
Sbjct: 1823 SEASTL 1828



 Score = 32.0 bits (71), Expect = 1.9
 Identities = 23/106 (21%), Positives = 43/106 (40%)

Query: 437 KINLSSDQNKSVSESNNDDVMLISVESPNLTTPITSNPTDTRKITSGNSSNSPNAEVMAV 496
           K  +++    S S +  +D  + +      +TP+TS P  T  + S  +SN     V + 
Sbjct: 421 KTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSK 480

Query: 497 QKKLDSIIDLTKEGLSNCNTESPVSPLESHSKAASNSKETTPLAQN 542
            +   S    +    +  N+    +P E  +   S S  T P+A +
Sbjct: 481 TQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASS 526



 Score = 31.6 bits (70), Expect = 2.5
 Identities = 28/118 (23%), Positives = 50/118 (42%), Gaps = 15/118 (12%)

Query: 434 GSKKINLSSDQNKSVSESNNDDVMLISVESPNLTTPITSNPTDTRKITSGNSSNS----- 488
           G     ++  ++++ SES +D   L    + + ++P T   TD    T    S S     
Sbjct: 104 GVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSEESISSTMAF 163

Query: 489 ------PNAEV-MAVQKKLDSIIDLTKEGLSNCNTESPVSPLESHSKAASNSKETTPL 539
                 P+ E   ++  K+D    LT    S   + SP +P  +    ++NS+ +TPL
Sbjct: 164 VSTAPLPSFEAYTSLTYKVDMSTPLT---TSTQASSSPTTPESTTIPKSTNSEGSTPL 218



 Score = 31.2 bits (69), Expect = 3.3
 Identities = 33/157 (21%), Positives = 60/157 (38%), Gaps = 1/157 (0%)

Query: 399 VANSEAMILDKNLESVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNKSVSESNNDDVML 458
           VA+SEA  L       ++P+  S+        ++  S   +  S+ +  ++       +L
Sbjct: 700 VASSEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLL 759

Query: 459 ISVESPNL-TTPITSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDLTKEGLSNCNTE 517
            S E+  L TTP+ ++   T    +  S  +     M +    +    LT   +S     
Sbjct: 760 TSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVT 819

Query: 518 SPVSPLESHSKAASNSKETTPLAQNAVQVPESFEHLP 554
           SP +   S +   SNS  TT    ++   P     +P
Sbjct: 820 SPEASTLSTTPVDSNSPVTTSTEVSSSPTPAEGTSMP 856



 Score = 30.8 bits (68), Expect = 4.3
 Identities = 33/140 (23%), Positives = 54/140 (38%), Gaps = 1/140 (0%)

Query: 399 VANSEAMILDKNLESVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNKSVSESNNDDVML 458
           VA+SEA  L       ++P+  SS     S   E  S   +  S+ +  ++       ++
Sbjct: 523 VASSEASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLV 582

Query: 459 ISVE-SPNLTTPITSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDLTKEGLSNCNTE 517
           +S E S   TTP  SN   T    + +SS +     M      +    +T   +S     
Sbjct: 583 VSSEASTTSTTPADSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVA 642

Query: 518 SPVSPLESHSKAASNSKETT 537
           S  +   S +   SN+  TT
Sbjct: 643 SSEASTLSTTPVDSNTPVTT 662



 Score = 30.8 bits (68), Expect = 4.3
 Identities = 39/141 (27%), Positives = 59/141 (41%), Gaps = 9/141 (6%)

Query: 399 VANSEAMILDKNLESVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNKSVSESNNDDVML 458
           VA+SEA  L       N+P+  S+     S  +E  S   +  ++ +  ++    +  ++
Sbjct: 641 VASSEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLV 700

Query: 459 ISVESPNLTTPITSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDLTKEGLSNCNTES 518
            S E+  L+T  T   T T   TS  +S+SP     A      S+   T    S   T  
Sbjct: 701 ASSEASTLST--TPVDTSTPVTTSTEASSSPTTADGA------SMPTSTPSEGSTPLTSM 752

Query: 519 PVSPLESHSKAASNSKETTPL 539
           PVS     S  AS +  TTPL
Sbjct: 753 PVSKTLLTSSEAS-TLSTTPL 772



 Score = 30.4 bits (67), Expect = 5.6
 Identities = 37/187 (19%), Positives = 71/187 (37%), Gaps = 12/187 (6%)

Query: 399  VANSEAMILDKNLESVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNKSVSESNNDDVML 458
            VA SEA  L        +P+  S+        +E  S  I+   ++   ++  +   + +
Sbjct: 2940 VAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPV 2999

Query: 459  ISVESPNL-------TTPITSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSI-IDLTKEG 510
             S E+  L       +TP+T++   +   T+   +  P +        L SI +  T   
Sbjct: 3000 ASSEASTLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVA 3059

Query: 511  LSNCNTESPVSPLESHSKAASN---SKETTPLAQNAVQVPESFEHLPPLPEPPAPLPELV 567
            +   +T S  +P++S+S   ++   S   TP    ++ +    E   PL   P     + 
Sbjct: 3060 IPEASTLS-TTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVT 3118

Query: 568  DKTRDTL 574
                 TL
Sbjct: 3119 SSAISTL 3125



 Score = 30.4 bits (67), Expect = 5.6
 Identities = 32/171 (18%), Positives = 68/171 (39%), Gaps = 9/171 (5%)

Query: 399  VANSEAMILDKNLESVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNK-------SVSES 451
            VA  EA  L       NSP+  S+       P+E  S  I+  S+ +        S +  
Sbjct: 3058 VAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPV 3117

Query: 452  NNDDVMLISVESPNLTTPITSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDLTKEGL 511
             +  +  +S    + +TP+T++       T+   ++ P +        L  +   T   +
Sbjct: 3118 TSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVV 3177

Query: 512  SNCNTESPVSPLESHSKAASNSKETTPLAQNAVQVPES--FEHLPPLPEPP 560
            S+ ++    +P+++ +   ++++ T+        +P S   E + PL   P
Sbjct: 3178 SSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVP 3228



 Score = 29.6 bits (65), Expect = 9.6
 Identities = 31/141 (21%), Positives = 57/141 (40%), Gaps = 4/141 (2%)

Query: 399  VANSEAMILDKNLESVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNKSVSESNNDDVML 458
            V +S    L       ++P+  S+  +     SE  S   +  S+ +  ++      +++
Sbjct: 3117 VTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLV 3176

Query: 459  ISVESPNLT-TPI-TSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDLTKEGLSNCNT 516
            +S E   L+ TP+ TS P  T   T   SS +     +      + +  LT   +SN   
Sbjct: 3177 VSSEDSTLSATPVDTSTPVTTS--TEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPV 3234

Query: 517  ESPVSPLESHSKAASNSKETT 537
             S  + + S +   SN+  TT
Sbjct: 3235 ASSEASILSTTPVDSNTPLTT 3255


>gi|119372317 xin actin-binding repeat containing 2 isoform 1 [Homo
            sapiens]
          Length = 3549

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 126/585 (21%), Positives = 217/585 (37%), Gaps = 91/585 (15%)

Query: 36   EALKTAIGSNVPSGNQSFSPSVITRTTEITKCSPSENGASSLDSNKNSISEKSKVFSQNC 95
            E +K  + S + S +Q+ +   +T+T EI K     N  ++L S K S S + K   Q  
Sbjct: 1835 EIIKGDLTSTLNSLSQAVNQKTVTKTEEIIK----GNMLATLKSLKES-SHRWKESKQPD 1889

Query: 96   IKPVEEIVHSETKLEQVVCSYQKPSRTTESPSRVFTEEAKDSLNTSENDSEHQTNVTRSL 155
              P +        +E+ +   +K + T     +   E  KD L TS           RSL
Sbjct: 1890 AIPGD--------IEKAIECLEKATNTKTEILK--KELLKDDLETS----------LRSL 1929

Query: 156  FEHEGACSLKSSCCPPSVLSGVVQMPESTVTS-TVGDKKTDQMVFHLETNSNSESHDKRQ 214
             E + +              GV++     V + + G++KTD     ++ N NS    K  
Sbjct: 1930 KEAQRSFKEVHK-------EGVIKKDAKAVMAGSSGEQKTDIHQVAVQRNKNSLLQPKPG 1982

Query: 215  SDNILCSEDSGFVPVEKTP------NLVNSVTSNNCADDILKTDECSRTSISNCESADST 268
                      G   + +T       NLV   T  N    + K  + +   + + E  +  
Sbjct: 1983 PFEPAAKWQGGADTLSQTMGKSCHGNLVEERTEVN----LPKAPKGTVKIVIDREQNNDA 2038

Query: 269  WQSSLDTNNNSHYQKKRMFSENEENVKRMKTSEQINENICVSLERQTAFLEQVRHLIQQE 328
             + SL   +NSH++   + S ++  V    T EQ   +  +S  + T+ +    +L  +E
Sbjct: 2039 LEKSLRRLSNSHHKSNVLESGDKTGVWTDTTGEQHLRDEYMS-RQLTSTVSVKNNLTTKE 2097

Query: 329  IYSINYELFDKKLKELNQRIGKT-------ECRNKHEGIADKLLAKIAKLQRRIKTVLLF 381
                  EL    +    Q  GKT       E RN H+ + +    K  K  + IK  +L 
Sbjct: 2098 SDRAVRELKKDDVFNSIQSAGKTVGKQQTYELRNDHQKM-EGFHIKSPKKTKNIK--ILT 2154

Query: 382  QRNCLKPNMLSSNGASKVANSEAMILDKNLESVNSPIEKSSVNYEPSNPSEKGSKKINLS 441
                 KP+      +  V  +           ++   +K ++  + +  S K  KK N++
Sbjct: 2155 DTQSSKPSPTQHPVSMPVGGTY---------DLSGDFQKQTLLKQETKYSNKDIKKKNIN 2205

Query: 442  SDQNKSV----SESNNDDVMLISVESPNLTTPITSNPTDTRKITSGNS----SNSPNAEV 493
                  +     +++N   M +S +S N T   T+   +T            +N+     
Sbjct: 2206 LQPMWQLLPVEQDTSNVTEMKVSEKSHN-TFKATNKKRETDVHLKSQDFLMKTNTSTGLK 2264

Query: 494  MAVQKKLDSIIDLTKEGL--SNCNTESPVSPLESHSKAASNSKETTPLAQNAVQVPES-- 549
            MA+++ L+ I    +  +  S C    P  P    S A+S  +   P     +  PE   
Sbjct: 2265 MAMERSLNPINFNPENNVKESECPLPPPSPPPPPPSNASSEIEFPLPPPPPLMMFPEKNG 2324

Query: 550  -------------FEHLPPLPEPPAPLPELVDKTRDT--LPPQKP 579
                         FE  P LP PP P+ E  ++   +  LPP  P
Sbjct: 2325 FLPSLSTEKIKAEFESFPGLPLPPPPVDEKSERESSSMFLPPPPP 2369


>gi|27262622 neuron navigator 1 [Homo sapiens]
          Length = 1874

 Score = 38.9 bits (89), Expect = 0.016
 Identities = 63/294 (21%), Positives = 109/294 (37%), Gaps = 53/294 (18%)

Query: 251  TDECSRTSISNCESADSTWQSSLDTNNNSHYQK-KRMFSENEENVKRMKTSEQINENICV 309
            TD+   + +S   SA ST+ S+ +   +   +K +R    ++E V  + +    N N+  
Sbjct: 1053 TDDVHGSVLSLASSASSTYSSAEERMQSEQIRKLRRELESSQEKVATLTSQLSANANLVA 1112

Query: 310  SLERQTAFL-EQVRHLIQQEIYSINYELFDKKLKELNQRIGKTECRNKHEGIADKLLAKI 368
            + E+    +  ++RHL +        E  D +L +L + I             D L  K 
Sbjct: 1113 AFEQSLVNMTSRLRHLAETA------EEKDTELLDLRETI-------------DFLKKKN 1153

Query: 369  AKLQRRIKTVLLFQRNCLKPNMLSSNGASKVANSEAMILDKN----LESVNSPIEKSSVN 424
            ++ Q  I+  L                AS+    E  I  +N    + S+NS    SS+ 
Sbjct: 1154 SEAQAVIQGAL---------------NASETTPKELRIKRQNSSDSISSLNSITSHSSIG 1198

Query: 425  YEPSNPSEKGSKKINLSSDQNKSVSESNNDDVMLISVESPNLTTPITSNPTDTRKITSGN 484
                  ++K  KK  L S  NK+ S            +   + TP +S P          
Sbjct: 1199 SSKDADAKKKKKKSWLRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAP---------- 1248

Query: 485  SSNSPNAEVMAVQKKLDSIIDLTKEGLSNCNTESPVSPLESHSKAASNSKETTP 538
              +SP  +  + +    SI   T   +    TE P  P   H++    ++E  P
Sbjct: 1249 --SSPKLQHGSTETASPSIKSSTSSSVGTDVTEGPAHP-APHTRLFHANEEEEP 1299


>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
           [Homo sapiens]
          Length = 1481

 Score = 38.5 bits (88), Expect = 0.021
 Identities = 116/601 (19%), Positives = 215/601 (35%), Gaps = 81/601 (13%)

Query: 6   RSKRKILKAKKTMPLSCRKQVEMLNKSRNVEALKTAIGSNVPSGNQSFSPSVITRTTEIT 65
           R  R +LKAK+T      K  E+ +KS +   +K  I  +    N+           ++ 
Sbjct: 117 RRSRDLLKAKQTEK---EKSQEVSSKSGS---MKDRISGSSKRSNEETDDY---GKAQVA 167

Query: 66  KCSPSENGASSLDSNKNSISEKSKVFSQNCIKPVEEIVHSETKLEQVVCSYQKPSRTTES 125
           K S  E+ +S L   K     + K   ++  K      H + +  +   +   P R + S
Sbjct: 168 KSSSKESRSSKLHKEKTRKERELKSGHKDRSKS-----HRKRETPKSYKTVDSPKRRSRS 222

Query: 126 PSRVFTEEAK--DSLNTSENDSEHQTNVTRS--------LFEHEGACSLKSSCCPPSVLS 175
           P R +++ +K  DS + +    ++  + +RS          +  G+ S + S  PP    
Sbjct: 223 PHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPP---- 278

Query: 176 GVVQMPESTVTSTVGDKKTDQMVFHLETNSNSESHDKRQSDNILCSEDSGFVPVEKTPNL 235
              + P +  +ST       +    +   S   S    +S +      SG  P       
Sbjct: 279 --YKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSGSY-----SGRSP------- 324

Query: 236 VNSVTSNNCADDILKTDECSRTSISNCESADSTWQSSLDTNNNSHYQKKRMFSENEENVK 295
            +       +   L     SR+ + + +S  S  +S   + ++S + KK+  S    +  
Sbjct: 325 -SPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRHSS 383

Query: 296 RMKTSEQINENICVSLERQTAFLEQVRHLIQQEIYSINYELFDKKLKELNQRIGKTECRN 355
                  +N ++   L R+           ++   +   ++  K+ K     + + E  +
Sbjct: 384 ISPVRLPLNSSLGAELSRKKK---------ERAAAAAAAKMDGKESKGSPVFLPRKENSS 434

Query: 356 ---KHEGIADKLLAKIAKLQRRIKTVLLFQRNCLKPNMLSSNGASKVANSEAMILDKNLE 412
              K  G+  K L +  KL++      L     L   + +S+   KV       LD+N E
Sbjct: 435 VEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGKVK------LDENSE 488

Query: 413 SVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNKSVSESNNDDVMLISVESPNLTTPITS 472
                  K+    + +  S+  + K  + + +    SE       L ++ SP    P T+
Sbjct: 489 KHLVKDLKA----QGTRDSKPIALKEEIVTPKETETSEKETPPP-LPTIASPPPPLPTTT 543

Query: 473 NPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDLTKEGLSNCNTESPVSPLESHSKAASN 532
            P  T  +        P    +  Q  L        +  ++  +  P S     S  +S 
Sbjct: 544 PPPQTPPLPP-----LPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQ 598

Query: 533 SKETTPL---AQNAVQVPESFEHLPPLPEPPAPLPEL------VDKTRDTLPPQKPELKV 583
           +    P+    +  V V  +  HL     PP PLP L      +D  ++TL P KP  K 
Sbjct: 599 ANSQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETL-PSKPVKKE 657

Query: 584 K 584
           K
Sbjct: 658 K 658


>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
           [Homo sapiens]
          Length = 1490

 Score = 38.5 bits (88), Expect = 0.021
 Identities = 116/601 (19%), Positives = 215/601 (35%), Gaps = 81/601 (13%)

Query: 6   RSKRKILKAKKTMPLSCRKQVEMLNKSRNVEALKTAIGSNVPSGNQSFSPSVITRTTEIT 65
           R  R +LKAK+T      K  E+ +KS +   +K  I  +    N+           ++ 
Sbjct: 117 RRSRDLLKAKQTEK---EKSQEVSSKSGS---MKDRISGSSKRSNEETDDY---GKAQVA 167

Query: 66  KCSPSENGASSLDSNKNSISEKSKVFSQNCIKPVEEIVHSETKLEQVVCSYQKPSRTTES 125
           K S  E+ +S L   K     + K   ++  K      H + +  +   +   P R + S
Sbjct: 168 KSSSKESRSSKLHKEKTRKERELKSGHKDRSKS-----HRKRETPKSYKTVDSPKRRSRS 222

Query: 126 PSRVFTEEAK--DSLNTSENDSEHQTNVTRS--------LFEHEGACSLKSSCCPPSVLS 175
           P R +++ +K  DS + +    ++  + +RS          +  G+ S + S  PP    
Sbjct: 223 PHRKWSDSSKQDDSPSGASYGQDYDLSPSRSHTSSNYDSYKKSPGSTSRRQSVSPP---- 278

Query: 176 GVVQMPESTVTSTVGDKKTDQMVFHLETNSNSESHDKRQSDNILCSEDSGFVPVEKTPNL 235
              + P +  +ST       +    +   S   S    +S +      SG  P       
Sbjct: 279 --YKEPSAYQSSTRSPSPYSRRQRSVSPYSRRRSSSYERSGSY-----SGRSP------- 324

Query: 236 VNSVTSNNCADDILKTDECSRTSISNCESADSTWQSSLDTNNNSHYQKKRMFSENEENVK 295
            +       +   L     SR+ + + +S  S  +S   + ++S + KK+  S    +  
Sbjct: 325 -SPYGRRRSSSPFLSKRSLSRSPLPSRKSMKSRSRSPAYSRHSSSHSKKKRSSSRSRHSS 383

Query: 296 RMKTSEQINENICVSLERQTAFLEQVRHLIQQEIYSINYELFDKKLKELNQRIGKTECRN 355
                  +N ++   L R+           ++   +   ++  K+ K     + + E  +
Sbjct: 384 ISPVRLPLNSSLGAELSRKKK---------ERAAAAAAAKMDGKESKGSPVFLPRKENSS 434

Query: 356 ---KHEGIADKLLAKIAKLQRRIKTVLLFQRNCLKPNMLSSNGASKVANSEAMILDKNLE 412
              K  G+  K L +  KL++      L     L   + +S+   KV       LD+N E
Sbjct: 435 VEAKDSGLESKKLPRSVKLEKSAPDTELVNVTHLNTEVKNSSDTGKVK------LDENSE 488

Query: 413 SVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNKSVSESNNDDVMLISVESPNLTTPITS 472
                  K+    + +  S+  + K  + + +    SE       L ++ SP    P T+
Sbjct: 489 KHLVKDLKA----QGTRDSKPIALKEEIVTPKETETSEKETPPP-LPTIASPPPPLPTTT 543

Query: 473 NPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDLTKEGLSNCNTESPVSPLESHSKAASN 532
            P  T  +        P    +  Q  L        +  ++  +  P S     S  +S 
Sbjct: 544 PPPQTPPLPP-----LPPIPALPQQPPLPPSQPAFSQVPASSTSTLPPSTHSKTSAVSSQ 598

Query: 533 SKETTPL---AQNAVQVPESFEHLPPLPEPPAPLPEL------VDKTRDTLPPQKPELKV 583
           +    P+    +  V V  +  HL     PP PLP L      +D  ++TL P KP  K 
Sbjct: 599 ANSQPPVQVSVKTQVSVTAAIPHLKTSTLPPLPLPPLLPGDDDMDSPKETL-PSKPVKKE 657

Query: 584 K 584
           K
Sbjct: 658 K 658


>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
           precursor [Homo sapiens]
          Length = 513

 Score = 38.1 bits (87), Expect = 0.027
 Identities = 37/138 (26%), Positives = 65/138 (47%), Gaps = 18/138 (13%)

Query: 408 DKNLESVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNKSVSESNNDDVMLISVESPNLT 467
           D   +S  +  ++ S N +   PS + S++ NLSS +N   SES  + V     ++P+ T
Sbjct: 316 DSQEDSKENLSQEESQNVD--GPSSESSQEANLSSQENS--SESQEEVVSESRGDNPDPT 371

Query: 468 TPITSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDLTKEGLSNCNTESPVSP----- 522
           T    +  D+      +S    +++  + +++ DS    + E L N + ESP SP     
Sbjct: 372 TSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADS---ESSESL-NFSEESPESPEDENS 427

Query: 523 -----LESHSKAASNSKE 535
                L+SHS +A +  E
Sbjct: 428 SSQEGLQSHSSSAESQSE 445



 Score = 31.2 bits (69), Expect = 3.3
 Identities = 31/149 (20%), Positives = 61/149 (40%), Gaps = 7/149 (4%)

Query: 392 SSNGASKVANSEAMILDKNLESVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNKSVSES 451
           S  G S++ ++     +    S  +  + S  +    +PS K  +K  +S + ++S  + 
Sbjct: 225 SERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDD 284

Query: 452 NN--DDVMLISVESPNLTTPITSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDLTKE 509
           NN  ++V   S E+ N      S P   R+ + G+S       +   Q++  ++   + E
Sbjct: 285 NNTMEEVKSDSTENSNSRDTGLSQP---RRDSKGDSQEDSKENLS--QEESQNVDGPSSE 339

Query: 510 GLSNCNTESPVSPLESHSKAASNSKETTP 538
                N  S  +  ES  +  S S+   P
Sbjct: 340 SSQEANLSSQENSSESQEEVVSESRGDNP 368


>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
           precursor [Homo sapiens]
          Length = 497

 Score = 38.1 bits (87), Expect = 0.027
 Identities = 37/138 (26%), Positives = 65/138 (47%), Gaps = 18/138 (13%)

Query: 408 DKNLESVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNKSVSESNNDDVMLISVESPNLT 467
           D   +S  +  ++ S N +   PS + S++ NLSS +N   SES  + V     ++P+ T
Sbjct: 300 DSQEDSKENLSQEESQNVD--GPSSESSQEANLSSQENS--SESQEEVVSESRGDNPDPT 355

Query: 468 TPITSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDLTKEGLSNCNTESPVSP----- 522
           T    +  D+      +S    +++  + +++ DS    + E L N + ESP SP     
Sbjct: 356 TSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADS---ESSESL-NFSEESPESPEDENS 411

Query: 523 -----LESHSKAASNSKE 535
                L+SHS +A +  E
Sbjct: 412 SSQEGLQSHSSSAESQSE 429



 Score = 31.2 bits (69), Expect = 3.3
 Identities = 31/149 (20%), Positives = 61/149 (40%), Gaps = 7/149 (4%)

Query: 392 SSNGASKVANSEAMILDKNLESVNSPIEKSSVNYEPSNPSEKGSKKINLSSDQNKSVSES 451
           S  G S++ ++     +    S  +  + S  +    +PS K  +K  +S + ++S  + 
Sbjct: 209 SERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDD 268

Query: 452 NN--DDVMLISVESPNLTTPITSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDLTKE 509
           NN  ++V   S E+ N      S P   R+ + G+S       +   Q++  ++   + E
Sbjct: 269 NNTMEEVKSDSTENSNSRDTGLSQP---RRDSKGDSQEDSKENLS--QEESQNVDGPSSE 323

Query: 510 GLSNCNTESPVSPLESHSKAASNSKETTP 538
                N  S  +  ES  +  S S+   P
Sbjct: 324 SSQEANLSSQENSSESQEEVVSESRGDNP 352


>gi|239743291 PREDICTED: mucin 3A, intestinal [Homo sapiens]
          Length = 1486

 Score = 38.1 bits (87), Expect = 0.027
 Identities = 49/238 (20%), Positives = 92/238 (38%), Gaps = 12/238 (5%)

Query: 44  SNVPSGNQSFSP--SVITRTTEITKCSPSENGASSLDSNKNSISEKSKVFSQNCIKPVEE 101
           S++P+   + +P  +++T TTEI+  S     +S++ S   S S      S   I   E 
Sbjct: 372 SSLPTTETATTPMTNLVTTTTEISSHSTPSFSSSTIYSTVTSHSTPRFTSS---ITTTET 428

Query: 102 IVHSETKLEQVVCSYQKPSRTTESPSRVFTEEAKDSLNTSENDSEHQTNVTRSLFEHEGA 161
             HS  +      +    ++TT   S  FT     +  TS +     +++T +      A
Sbjct: 429 PSHSTPRFTSSFTN----TKTTSHRSPSFTSLITTTETTSHSTPSFTSSITTTETTSHSA 484

Query: 162 CSLKSSCCPPSVLSGVVQMPESTVTSTVGDKKTDQMVFHLETNSNSESHDKRQSDNILCS 221
            S  SS       S   +   S++T+T  +  +        T + + SH      + + +
Sbjct: 485 RSFTSSITTTETTSHNTRSFTSSITTTETNSHSTTSFTSSITTTETTSHSTPSFSSSITT 544

Query: 222 EDSGFVPVEKTPNLVNSVTSNNCADDILKTDECSRTSISNCESADSTWQSSLDTNNNS 279
            ++   P+  TP L + VT+      I      S T+      +   + SS+ T   +
Sbjct: 545 TET---PLHSTPGLTSWVTTTKTTSHITPGLTSSITTTETTSHSTPGFTSSITTTETT 599



 Score = 31.2 bits (69), Expect = 3.3
 Identities = 26/107 (24%), Positives = 40/107 (37%), Gaps = 17/107 (15%)

Query: 467 TTPITSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDLTKEGLSNCNTESPVSPLESH 526
           T+PITS+ T T  +TS  ++ S       +     +I+  T              P+ S 
Sbjct: 256 TSPITSSITSTNTVTSMTTTASQPTATNTLSSPTRTILSST--------------PVLST 301

Query: 527 SKAASNSKETTPLAQNAVQVPESFEHLPPLPE---PPAPLPELVDKT 570
               S    TTPL+     +P +     P  E   P +P   + D T
Sbjct: 302 ETITSGITNTTPLSTLVTTLPTTISRSTPTSETTYPTSPTSTVTDST 348


>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
          Length = 3907

 Score = 38.1 bits (87), Expect = 0.027
 Identities = 37/156 (23%), Positives = 64/156 (41%), Gaps = 19/156 (12%)

Query: 9    RKILKAKKTMPLSCRKQVEMLNKSR--NVEALKTAIGSNVPSGNQSFSPSVITRTTEITK 66
            + + + K+ + L CR+   ++N +R  NV++  T + S +          V+T T     
Sbjct: 981  KSLKQEKEQVSLRCRELEIIINHNRAENVQSCDTQVSSLLDG--------VVTMT----- 1027

Query: 67   CSPSENGASSLDSNKNSISEKSKVFSQNCIKPVEEIVHSETKLEQVVCSYQKPSRTTESP 126
               S     S+     S  E+SK+  ++ +      V  E+K EQ++  +  PS T ES 
Sbjct: 1028 ---SRGAEGSVSKVNKSFGEESKIMVEDKVSFENMTVGEESKQEQLILDH-LPSVTKESS 1083

Query: 127  SRVFTEEAKDSLNTSENDSEHQTNVTRSLFEHEGAC 162
             R       D L    N  + + N  R   E +  C
Sbjct: 1084 LRATQPSENDKLQKELNVLKSEQNDLRLQMEAQRIC 1119


>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
          Length = 3899

 Score = 38.1 bits (87), Expect = 0.027
 Identities = 37/156 (23%), Positives = 64/156 (41%), Gaps = 19/156 (12%)

Query: 9    RKILKAKKTMPLSCRKQVEMLNKSR--NVEALKTAIGSNVPSGNQSFSPSVITRTTEITK 66
            + + + K+ + L CR+   ++N +R  NV++  T + S +          V+T T     
Sbjct: 981  KSLKQEKEQVSLRCRELEIIINHNRAENVQSCDTQVSSLLDG--------VVTMT----- 1027

Query: 67   CSPSENGASSLDSNKNSISEKSKVFSQNCIKPVEEIVHSETKLEQVVCSYQKPSRTTESP 126
               S     S+     S  E+SK+  ++ +      V  E+K EQ++  +  PS T ES 
Sbjct: 1028 ---SRGAEGSVSKVNKSFGEESKIMVEDKVSFENMTVGEESKQEQLILDH-LPSVTKESS 1083

Query: 127  SRVFTEEAKDSLNTSENDSEHQTNVTRSLFEHEGAC 162
             R       D L    N  + + N  R   E +  C
Sbjct: 1084 LRATQPSENDKLQKELNVLKSEQNDLRLQMEAQRIC 1119


>gi|154354979 myosin X [Homo sapiens]
          Length = 2058

 Score = 38.1 bits (87), Expect = 0.027
 Identities = 28/129 (21%), Positives = 56/129 (43%), Gaps = 2/129 (1%)

Query: 263 ESADSTWQSSLDTNN-NSHYQKKRMFSENEENVKRMKTSEQINENICVSLERQTAFLEQV 321
           ++ DST    L + + N+H+  K   + N   VK      Q +    +   R T F + +
Sbjct: 514 QATDSTLLEKLHSQHANNHFYVKPRVAVNNFGVKHYAGEVQYDVRGILEKNRDT-FRDDL 572

Query: 322 RHLIQQEIYSINYELFDKKLKELNQRIGKTECRNKHEGIADKLLAKIAKLQRRIKTVLLF 381
            +L+++  +   Y+LF+      NQ   K   +++   ++ +    +  L   + +   F
Sbjct: 573 LNLLRESRFDFIYDLFEHVSSRNNQDTLKCGSKHRRPTVSSQFKDSLHSLMATLSSSNPF 632

Query: 382 QRNCLKPNM 390
              C+KPNM
Sbjct: 633 FVRCIKPNM 641


>gi|155030218 PDS5, regulator of cohesion maintenance, homolog A
            isoform 2 [Homo sapiens]
          Length = 1297

 Score = 38.1 bits (87), Expect = 0.027
 Identities = 43/192 (22%), Positives = 71/192 (36%), Gaps = 25/192 (13%)

Query: 411  LESVNSPIEKSSVN-YEPSNPSEKGSKKINLSSDQNKS----------------VSESNN 453
            L +VN P+  +    Y  S  +E GS  IN++S+ N S                VSE+  
Sbjct: 1101 LGAVNKPLSATGRKPYVRSTGTETGSN-INVNSELNPSTGNRSREQSSEAAETGVSENEE 1159

Query: 454  DDVMLISVESPNLTTPITSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDLTKEGLSN 513
            + V +ISV       P+ +   ++ + T GN S+    +        ++I   T E +  
Sbjct: 1160 NPVRIISVTPVKNIDPVKNKEINSDQATQGNISSDRGKKRTVTAAGAENIQQKTDEKVDE 1219

Query: 514  CNTESPVSP-------LESHSKAASNSKETTPLAQNAVQVPESFEHLPPLPEPPAPLPEL 566
                +P  P        ES   A  N     P+ +   +     E    L    A  P+L
Sbjct: 1220 SGPPAPSKPRRGRRPKSESQGNATKNDDLNKPINKGRKRAAVGQESPGGLEAGNAKAPKL 1279

Query: 567  VDKTRDTLPPQK 578
             D  +   P ++
Sbjct: 1280 QDLAKKAAPAER 1291


>gi|155030216 PDS5, regulator of cohesion maintenance, homolog A
            isoform 1 [Homo sapiens]
          Length = 1337

 Score = 38.1 bits (87), Expect = 0.027
 Identities = 43/192 (22%), Positives = 71/192 (36%), Gaps = 25/192 (13%)

Query: 411  LESVNSPIEKSSVN-YEPSNPSEKGSKKINLSSDQNKS----------------VSESNN 453
            L +VN P+  +    Y  S  +E GS  IN++S+ N S                VSE+  
Sbjct: 1141 LGAVNKPLSATGRKPYVRSTGTETGSN-INVNSELNPSTGNRSREQSSEAAETGVSENEE 1199

Query: 454  DDVMLISVESPNLTTPITSNPTDTRKITSGNSSNSPNAEVMAVQKKLDSIIDLTKEGLSN 513
            + V +ISV       P+ +   ++ + T GN S+    +        ++I   T E +  
Sbjct: 1200 NPVRIISVTPVKNIDPVKNKEINSDQATQGNISSDRGKKRTVTAAGAENIQQKTDEKVDE 1259

Query: 514  CNTESPVSP-------LESHSKAASNSKETTPLAQNAVQVPESFEHLPPLPEPPAPLPEL 566
                +P  P        ES   A  N     P+ +   +     E    L    A  P+L
Sbjct: 1260 SGPPAPSKPRRGRRPKSESQGNATKNDDLNKPINKGRKRAAVGQESPGGLEAGNAKAPKL 1319

Query: 567  VDKTRDTLPPQK 578
             D  +   P ++
Sbjct: 1320 QDLAKKAAPAER 1331


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.124    0.346 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,119,036
Number of Sequences: 37866
Number of extensions: 1239178
Number of successful extensions: 6649
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 285
Number of HSP's that attempted gapping in prelim test: 5999
Number of HSP's gapped (non-prelim): 817
length of query: 682
length of database: 18,247,518
effective HSP length: 109
effective length of query: 573
effective length of database: 14,120,124
effective search space: 8090831052
effective search space used: 8090831052
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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