Guide to the Human Genome
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Search of human proteins with 34577061

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|34577061 class I alcohol dehydrogenase, beta subunit [Homo
sapiens]
         (375 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|34577061 class I alcohol dehydrogenase, beta subunit [Homo sa...   761   0.0  
gi|4501933 class I alcohol dehydrogenase, gamma subunit [Homo sa...   726   0.0  
gi|4501929 class I alcohol dehydrogenase, alpha subunit [Homo sa...   717   0.0  
gi|71743840 class IV alcohol dehydrogenase, mu or sigma subunit ...   554   e-158
gi|71565154 class III alcohol dehydrogenase, chi subunit [Homo s...   496   e-140
gi|156523966 class V alcohol dehydrogenase isoform 1 [Homo sapiens]   487   e-138
gi|4501939 class V alcohol dehydrogenase isoform 2 [Homo sapiens]     481   e-136
gi|71565152 class II alcohol dehydrogenase, pi subunit [Homo sap...   469   e-132
gi|156627571 sorbitol dehydrogenase [Homo sapiens]                     93   4e-19
gi|194239674 crystallin, zeta isoform a [Homo sapiens]                 60   4e-09
gi|13236495 crystallin, zeta isoform a [Homo sapiens]                  60   4e-09
gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform a...    59   9e-09
gi|194239676 crystallin, zeta isoform b [Homo sapiens]                 51   2e-06
gi|18379349 vesicle amine transport protein 1 [Homo sapiens]           49   7e-06
gi|67078406 trans-2-enoyl-CoA reductase, mitochondrial isoform b...    46   6e-05
gi|28557745 zinc binding alcohol dehydrogenase domain containing...    44   2e-04
gi|24308257 vesicle amine transport protein 1 homolog (T. califo...    43   5e-04
gi|41872631 fatty acid synthase [Homo sapiens]                         37   0.022
gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens]       37   0.029
gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens]       37   0.029
gi|90669511 crystallin, zeta-like 1 [Homo sapiens]                     35   0.11 
gi|169203160 PREDICTED: hypothetical protein [Homo sapiens]            32   0.71 
gi|169203656 PREDICTED: hypothetical protein [Homo sapiens]            32   0.71 
gi|169202387 PREDICTED: hypothetical protein [Homo sapiens]            32   0.71 
gi|226059159 prostaglandin reductase 1 isoform 1 [Homo sapiens]        30   4.6  
gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens]        30   4.6  
gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens]        30   4.6  
gi|56788377 nucleoporin like 1 isoform b [Homo sapiens]                30   4.6  
gi|30102928 nucleoporin like 1 isoform a [Homo sapiens]                30   4.6  
gi|194018457 N-acetylgalactosaminyltransferase-like 6 [Homo sapi...    29   6.0  

>gi|34577061 class I alcohol dehydrogenase, beta subunit [Homo
           sapiens]
          Length = 375

 Score =  761 bits (1964), Expect = 0.0
 Identities = 375/375 (100%), Positives = 375/375 (100%)

Query: 1   MSTAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICHTDDHVVSGNLVT 60
           MSTAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICHTDDHVVSGNLVT
Sbjct: 1   MSTAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICHTDDHVVSGNLVT 60

Query: 61  PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNP 120
           PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNP
Sbjct: 61  PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNP 120

Query: 121 RGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180
           RGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG
Sbjct: 121 RGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180

Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240
           YGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATE
Sbjct: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240

Query: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQ 300
           CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQ
Sbjct: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQ 300

Query: 301 NLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGF 360
           NLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGF
Sbjct: 301 NLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGF 360

Query: 361 DLLHSGKSIRTVLTF 375
           DLLHSGKSIRTVLTF
Sbjct: 361 DLLHSGKSIRTVLTF 375


>gi|4501933 class I alcohol dehydrogenase, gamma subunit [Homo
           sapiens]
          Length = 375

 Score =  726 bits (1873), Expect = 0.0
 Identities = 354/375 (94%), Positives = 366/375 (97%)

Query: 1   MSTAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICHTDDHVVSGNLVT 60
           MSTAGKVIKCKAAVLWE+KKPFSIE+VEVAPPKA+EVRIKMVA GIC +D+HVVSGNLVT
Sbjct: 1   MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVT 60

Query: 61  PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNP 120
           PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCR+CKNPESNYCLKNDLGNP
Sbjct: 61  PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNP 120

Query: 121 RGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180
           RGTLQDGTRRFTC GKPIHHF+G STFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG
Sbjct: 121 RGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180

Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240
           YGSAV VAKVTPGSTCAVFGLGGVGLS VMGCKAAGAARIIAVDINKDKFAKAKELGATE
Sbjct: 181 YGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240

Query: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQ 300
           CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP SQ
Sbjct: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ 300

Query: 301 NLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGF 360
           NLSINPMLLLTGRTWKGA++GGFKSKE +PKLVADFMAKKFSLDALIT++LPFEKINEGF
Sbjct: 301 NLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGF 360

Query: 361 DLLHSGKSIRTVLTF 375
           DLL SGKSIRTVLTF
Sbjct: 361 DLLRSGKSIRTVLTF 375


>gi|4501929 class I alcohol dehydrogenase, alpha subunit [Homo
           sapiens]
          Length = 375

 Score =  717 bits (1850), Expect = 0.0
 Identities = 351/375 (93%), Positives = 363/375 (96%)

Query: 1   MSTAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICHTDDHVVSGNLVT 60
           MSTAGKVIKCKAAVLWE+KKPFSIE+VEVAPPKA+EVRIKMVAVGIC TDDHVVSG +VT
Sbjct: 1   MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVT 60

Query: 61  PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNP 120
           PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPL  PQCGKCR+CKNPESNYCLKND+ NP
Sbjct: 61  PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNP 120

Query: 121 RGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180
           +GTLQDGT RFTCR KPIHHFLG STFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG
Sbjct: 121 QGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180

Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240
           YGSAVNVAKVTPGSTCAVFGLGGVGLSA+MGCKAAGAARIIAVDINKDKFAKAKELGATE
Sbjct: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATE 240

Query: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQ 300
           CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP SQ
Sbjct: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ 300

Query: 301 NLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGF 360
           NLS+NPMLLLTGRTWKGA+ GGFKSKE +PKLVADFMAKKFSLDALITHVLPFEKINEGF
Sbjct: 301 NLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGF 360

Query: 361 DLLHSGKSIRTVLTF 375
           DLLHSGKSIRT+L F
Sbjct: 361 DLLHSGKSIRTILMF 375


>gi|71743840 class IV alcohol dehydrogenase, mu or sigma subunit
           [Homo sapiens]
          Length = 386

 Score =  554 bits (1427), Expect = e-158
 Identities = 259/375 (69%), Positives = 315/375 (84%), Gaps = 1/375 (0%)

Query: 1   MSTAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICHTDDHVVSGNLVT 60
           M TAGKVIKCKAAVLWE K+PFSIE++EVAPPK  EVRIK++A GIC TDDHV+ G +V+
Sbjct: 13  MGTAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVS 72

Query: 61  PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNP 120
             PVI+GHEA GIVES+GEGVTTVKPGDKVIPLF PQC +C  C+NP+ N C+++D+   
Sbjct: 73  KFPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITG- 131

Query: 121 RGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180
           RG L DGT RFTC+GKP+HHF+ TSTF++YTVVDE++VAKID A+P EKVCLIGCGFSTG
Sbjct: 132 RGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTG 191

Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240
           YG+AV   KV PGSTC VFGLGGVGLS +MGCK+AGA+RII +D+NKDKF KA  +GATE
Sbjct: 192 YGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATE 251

Query: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQ 300
           CI+P+D  KPI EVL EMT   V ++FEVIG L+TM+ +L  CH   GTSV+VGVPP+++
Sbjct: 252 CISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAK 311

Query: 301 NLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGF 360
            L+ +PMLL TGRTWKG V+GG KS++ +PKLV +F+AKKF LD LITHVLPF+KI+EGF
Sbjct: 312 MLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGF 371

Query: 361 DLLHSGKSIRTVLTF 375
           +LL+SG+SIRTVLTF
Sbjct: 372 ELLNSGQSIRTVLTF 386


>gi|71565154 class III alcohol dehydrogenase, chi subunit [Homo
           sapiens]
          Length = 374

 Score =  496 bits (1278), Expect = e-140
 Identities = 235/373 (63%), Positives = 294/373 (78%), Gaps = 5/373 (1%)

Query: 4   AGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICHTDDHVVSGNLVTP-- 61
           A +VIKCKAAV WE  KP SIE++EVAPPKA+EVRIK++A  +CHTD + +SG    P  
Sbjct: 2   ANEVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSG--ADPEG 59

Query: 62  -LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNP 120
             PVILGHE AGIVESVGEGVT +K GD VIPL+ PQCG+C+ C NP++N C K  +   
Sbjct: 60  CFPVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQG 119

Query: 121 RGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180
           +G + DGT RFTC+GK I H++GTSTFS+YTVV + +VAKID  +PL+KVCL+GCG STG
Sbjct: 120 KGLMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTG 179

Query: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240
           YG+AVN AK+ PGS CAVFGLGGVGL+ +MGCK AGA+RII VDINKDKFA+AKE GATE
Sbjct: 180 YGAAVNTAKLEPGSVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATE 239

Query: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQ 300
           CINPQD+ KPIQEVL EMTDGGVD+SFE IG +  M A+L  CH+  G SV+VGV  + +
Sbjct: 240 CINPQDFSKPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGE 299

Query: 301 NLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGF 360
            ++  P  L+TGRTWKG  +GG+KS E +PKLV+++M+KK  +D  +TH L F++IN+ F
Sbjct: 300 EIATRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAF 359

Query: 361 DLLHSGKSIRTVL 373
           +L+HSGKSIRTV+
Sbjct: 360 ELMHSGKSIRTVV 372


>gi|156523966 class V alcohol dehydrogenase isoform 1 [Homo sapiens]
          Length = 375

 Score =  487 bits (1253), Expect = e-138
 Identities = 241/374 (64%), Positives = 295/374 (78%), Gaps = 2/374 (0%)

Query: 1   MSTAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICHTDDHVV-SGNLV 59
           MST G+VI+CKAA+LW+   PFSIE+VEVAPPKA EVRIK+VA G+C T+  V+ S +L 
Sbjct: 1   MSTTGQVIRCKAAILWKPGAPFSIEEVEVAPPKAKEVRIKVVATGLCGTEMKVLGSKHLD 60

Query: 60  TPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGN 119
              P ILGHE AGIVES+GEGV+TVKPGDKVI LF PQCG+C  C N E N+C++     
Sbjct: 61  LLYPTILGHEGAGIVESIGEGVSTVKPGDKVITLFLPQCGECTSCLNSEGNFCIQFKQSK 120

Query: 120 PRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFST 179
            +  + DGT RFTC+GK I+HF  TSTF +YTV+ E +VAKIDA +PLEKVCLI CGFST
Sbjct: 121 TQ-LMSDGTSRFTCKGKSIYHFGNTSTFCEYTVIKEISVAKIDAVAPLEKVCLISCGFST 179

Query: 180 GYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGAT 239
           G+G+A+N AKVTPGSTCAVFGLGGVGLS VMGCKAAGAARII VD+NK+KF KA+ELGAT
Sbjct: 180 GFGAAINTAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIGVDVNKEKFKKAQELGAT 239

Query: 240 ECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPAS 299
           EC+NPQD KKPIQEVL +MTD G+DF FE IG LD + A+L  C+E+ G  V+VGV PAS
Sbjct: 240 ECLNPQDLKKPIQEVLFDMTDAGIDFCFEAIGNLDVLAAALASCNESYGVCVVVGVLPAS 299

Query: 300 QNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEG 359
             L I+  L  +GR+ KG+V+GG+KS++ IPKLVAD+MA+K +LD LITH L  +KINE 
Sbjct: 300 VQLKISGQLFFSGRSLKGSVFGGWKSRQHIPKLVADYMAEKLNLDPLITHTLNLDKINEA 359

Query: 360 FDLLHSGKSIRTVL 373
            +L+ +GK IR +L
Sbjct: 360 VELMKTGKCIRCIL 373


>gi|4501939 class V alcohol dehydrogenase isoform 2 [Homo sapiens]
          Length = 368

 Score =  481 bits (1239), Expect = e-136
 Identities = 238/368 (64%), Positives = 291/368 (79%), Gaps = 2/368 (0%)

Query: 1   MSTAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICHTDDHVV-SGNLV 59
           MST G+VI+CKAA+LW+   PFSIE+VEVAPPKA EVRIK+VA G+C T+  V+ S +L 
Sbjct: 1   MSTTGQVIRCKAAILWKPGAPFSIEEVEVAPPKAKEVRIKVVATGLCGTEMKVLGSKHLD 60

Query: 60  TPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGN 119
              P ILGHE AGIVES+GEGV+TVKPGDKVI LF PQCG+C  C N E N+C++     
Sbjct: 61  LLYPTILGHEGAGIVESIGEGVSTVKPGDKVITLFLPQCGECTSCLNSEGNFCIQFKQSK 120

Query: 120 PRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFST 179
            +  + DGT RFTC+GK I+HF  TSTF +YTV+ E +VAKIDA +PLEKVCLI CGFST
Sbjct: 121 TQ-LMSDGTSRFTCKGKSIYHFGNTSTFCEYTVIKEISVAKIDAVAPLEKVCLISCGFST 179

Query: 180 GYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGAT 239
           G+G+A+N AKVTPGSTCAVFGLGGVGLS VMGCKAAGAARII VD+NK+KF KA+ELGAT
Sbjct: 180 GFGAAINTAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIGVDVNKEKFKKAQELGAT 239

Query: 240 ECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPAS 299
           EC+NPQD KKPIQEVL +MTD G+DF FE IG LD + A+L  C+E+ G  V+VGV PAS
Sbjct: 240 ECLNPQDLKKPIQEVLFDMTDAGIDFCFEAIGNLDVLAAALASCNESYGVCVVVGVLPAS 299

Query: 300 QNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEG 359
             L I+  L  +GR+ KG+V+GG+KS++ IPKLVAD+MA+K +LD LITH L  +KINE 
Sbjct: 300 VQLKISGQLFFSGRSLKGSVFGGWKSRQHIPKLVADYMAEKLNLDPLITHTLNLDKINEA 359

Query: 360 FDLLHSGK 367
            +L+ +GK
Sbjct: 360 VELMKTGK 367


>gi|71565152 class II alcohol dehydrogenase, pi subunit [Homo
           sapiens]
          Length = 380

 Score =  469 bits (1206), Expect = e-132
 Identities = 230/380 (60%), Positives = 288/380 (75%), Gaps = 5/380 (1%)

Query: 1   MSTAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICHTDDHVVSGNLV- 59
           M T GKVIKCKAA+ WE  KP  IE+VEVAPPKA+EVRI+++A  +CHTD  V+      
Sbjct: 1   MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG 60

Query: 60  TPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLK-NDLG 118
              PVI+GHEAAGIVES+G GVT VKPGDKVIPL+ P C KC+ C +P +N C K ++L 
Sbjct: 61  LAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLK 120

Query: 119 NPRGT---LQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGC 175
           +P      ++D T RFTC+GKP++HF GTSTFSQYTVV +  +AKID  + LE+VCL+GC
Sbjct: 121 SPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGC 180

Query: 176 GFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKE 235
           GFSTGYG+A+N AKVTPGSTCAVFGLGGVGLSAVMGCKAAGA+RII +DIN +KF KAK 
Sbjct: 181 GFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA 240

Query: 236 LGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGV 295
           LGAT+C+NP+D  KPIQEV+ E+T GGVDF+ +  G  +TM A+L C     G+   +GV
Sbjct: 241 LGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGV 300

Query: 296 PPASQNLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEK 355
              S+ L+I P  L+ GRT  G  +GG+KS + IPKLV D+  KKF+LDAL+TH LPF+K
Sbjct: 301 AAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDK 360

Query: 356 INEGFDLLHSGKSIRTVLTF 375
           I+E FDL++ GKS+RT+L F
Sbjct: 361 ISEAFDLMNQGKSVRTILIF 380


>gi|156627571 sorbitol dehydrogenase [Homo sapiens]
          Length = 357

 Score = 92.8 bits (229), Expect = 4e-19
 Identities = 97/365 (26%), Positives = 159/365 (43%), Gaps = 53/365 (14%)

Query: 24  IEDVEVAPPKAYEVRIKMVAVGICHTDDHVVS----GNLVTPLPVILGHEAAGIVESVGE 79
           +E+  +  P   EV ++M +VGIC +D H       GN +   P++LGHEA+G VE VG 
Sbjct: 22  LENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGS 81

Query: 80  GVTTVKPGDKV-IPLFTPQ-----CGKCRVCKNPESNYC-LKNDLGNPRGTLQDGTRRFT 132
            V  +KPGD+V I    P+     C   R   +P   +C    D GN             
Sbjct: 82  SVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGN------------L 129

Query: 133 CRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTP 192
           CR      F   +    Y + D     +     PL          S G   A     VT 
Sbjct: 130 CR------FYKHNAAFCYKLPDNVTFEEGALIEPL----------SVGI-HACRRGGVTL 172

Query: 193 GSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQ 252
           G    V G G +G+  ++  KA GAA+++  D++  + +KAKE+GA   +  Q  K+  Q
Sbjct: 173 GHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVL--QISKESPQ 230

Query: 253 EVLKEMTDGGV----DFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPML 308
           E+ +++ +G +    + + E  G   ++ A +       G  V+VG+      ++  P+L
Sbjct: 231 EIARKV-EGQLGCKPEVTIECTGAEASIQAGIYATRSG-GNLVLVGL---GSEMTTVPLL 285

Query: 309 LLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDLLHSGKS 368
               R  +  + G F+     P  ++   +K  ++  L+TH  P EK  E F+    G  
Sbjct: 286 HAAIR--EVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLG 343

Query: 369 IRTVL 373
           ++ +L
Sbjct: 344 LKIML 348


>gi|194239674 crystallin, zeta isoform a [Homo sapiens]
          Length = 329

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 63/284 (22%), Positives = 114/284 (40%), Gaps = 57/284 (20%)

Query: 26  DVEVAPPKAYEVRIKMVAVGICHTDDHVVSGNLVTP--LPVILGHEAAGIVESVGEGVTT 83
           D+ V  PK ++V IK+ A G+   + ++ SG       LP   G + AG++E+VG+  + 
Sbjct: 27  DIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIEAVGDNASA 86

Query: 84  VKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLG 143
            K GD+V    T   G                                            
Sbjct: 87  FKKGDRVFTSSTISGG-------------------------------------------- 102

Query: 144 TSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGL-G 202
              +++Y +  ++ V K+      ++   IG  + T Y + ++ A V  G +  V G  G
Sbjct: 103 ---YAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASG 159

Query: 203 GVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGG 262
           GVGL+A    +A G  +I+     ++      + GA E  N ++    I ++ K + + G
Sbjct: 160 GVGLAACQIARAYG-LKILGTAGTEEGQKIVLQNGAHEVFNHREVNY-IDKIKKYVGEKG 217

Query: 263 VDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINP 306
           +D   E++  ++      L  H   G  ++VG   +   + INP
Sbjct: 218 IDIIIEMLANVNLSKDLSLLSHG--GRVIVVG---SRGTIEINP 256


>gi|13236495 crystallin, zeta isoform a [Homo sapiens]
          Length = 329

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 63/284 (22%), Positives = 114/284 (40%), Gaps = 57/284 (20%)

Query: 26  DVEVAPPKAYEVRIKMVAVGICHTDDHVVSGNLVTP--LPVILGHEAAGIVESVGEGVTT 83
           D+ V  PK ++V IK+ A G+   + ++ SG       LP   G + AG++E+VG+  + 
Sbjct: 27  DIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIEAVGDNASA 86

Query: 84  VKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLG 143
            K GD+V    T   G                                            
Sbjct: 87  FKKGDRVFTSSTISGG-------------------------------------------- 102

Query: 144 TSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGL-G 202
              +++Y +  ++ V K+      ++   IG  + T Y + ++ A V  G +  V G  G
Sbjct: 103 ---YAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASG 159

Query: 203 GVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGG 262
           GVGL+A    +A G  +I+     ++      + GA E  N ++    I ++ K + + G
Sbjct: 160 GVGLAACQIARAYG-LKILGTAGTEEGQKIVLQNGAHEVFNHREVNY-IDKIKKYVGEKG 217

Query: 263 VDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINP 306
           +D   E++  ++      L  H   G  ++VG   +   + INP
Sbjct: 218 IDIIIEMLANVNLSKDLSLLSHG--GRVIVVG---SRGTIEINP 256


>gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform a
           [Homo sapiens]
          Length = 373

 Score = 58.5 bits (140), Expect = 9e-09
 Identities = 59/247 (23%), Positives = 98/247 (39%), Gaps = 56/247 (22%)

Query: 20  KPFSIEDVEVAPPKAYEVRIKMVAVGICHTDDHVVSGN--LVTPLPVILGHEAAGIVESV 77
           K   ++++E+A  +  +VR+KM+A  I  +D +++ GN   +  LP + G+E    V +V
Sbjct: 56  KVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAV 115

Query: 78  GEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKP 137
           G  VT +KPGD VIP                                             
Sbjct: 116 GSNVTGLKPGDWVIPANA------------------------------------------ 133

Query: 138 IHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPG-STC 196
                G  T+    V  E A+ ++ +  PL+    +G    T Y   ++  ++ PG S  
Sbjct: 134 -----GLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVI 188

Query: 197 AVFGLGGVGLSAVMGCKAAGAARIIAV----DINKDKFAKAKELGATECINPQDYKKP-I 251
                 GVG + +    A G   I  V    DI K    + K LGA   I  ++ ++P +
Sbjct: 189 QNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQK-LSDRLKSLGAEHVITEEELRRPEM 247

Query: 252 QEVLKEM 258
           +   K+M
Sbjct: 248 KNFFKDM 254


>gi|194239676 crystallin, zeta isoform b [Homo sapiens]
          Length = 295

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 45/194 (23%), Positives = 76/194 (39%), Gaps = 50/194 (25%)

Query: 26  DVEVAPPKAYEVRIKMVAVGICHTDDHVVSGNLVTP--LPVILGHEAAGIVESVGEGVTT 83
           D+ V  PK ++V IK+ A G+   + ++ SG       LP   G + AG++E+VG+  + 
Sbjct: 27  DIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIEAVGDNASA 86

Query: 84  VKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLG 143
            K GD+V    T   G                                            
Sbjct: 87  FKKGDRVFTSSTISGG-------------------------------------------- 102

Query: 144 TSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGL-G 202
              +++Y +  ++ V K+      ++   IG  + T Y + ++ A V  G +  V G  G
Sbjct: 103 ---YAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASG 159

Query: 203 GVGLSAVMGCKAAG 216
           GVGL+A    +A G
Sbjct: 160 GVGLAACQIARAYG 173


>gi|18379349 vesicle amine transport protein 1 [Homo sapiens]
          Length = 393

 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 86/369 (23%), Positives = 133/369 (36%), Gaps = 85/369 (23%)

Query: 32  PKAYEVRIKMVAVGICHTDDHVVSG--NLVTPLPVILGHEAAGIVESVGEGVTTVKPGDK 89
           P   ++ +++ A G+   D     G  + + PLPV  G E AG+V +VGEGV+  K GD+
Sbjct: 74  PGPGQLTLRLRACGLNFADLMARQGLYDRLPPLPVTPGMEGAGVVIAVGEGVSDRKAGDR 133

Query: 90  VIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQ 149
           V+ L                         N  G  Q                       +
Sbjct: 134 VMVL-------------------------NRSGMWQ-----------------------E 145

Query: 150 YTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAV-FGLGGVGLSA 208
              V       I  A   E+   +   + T Y    +   + PG +  V    GGVG++A
Sbjct: 146 EVTVPSVQTFLIPEAMTFEEAAALLVNYITAYMVLFDFGNLQPGHSVLVHMAAGGVGMAA 205

Query: 209 VMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY-KKPIQEVLKEMTDGGVDFSF 267
           V  C+      +     +  K    KE G T   +P DY      + +K+++  GVD   
Sbjct: 206 VQLCRTVENVTVFGT-ASASKHEALKENGVT---HPIDYHTTDYVDEIKKISPKGVDIVM 261

Query: 268 EVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNLSINPM--LLLTGRTW---------- 315
           + +G  DT     L   +  G  V  G+     NL   P   L+   RTW          
Sbjct: 262 DPLGGSDTAKGYNLL--KPMGKVVTYGM----ANLLTGPKRNLMALARTWWNQFSVTALQ 315

Query: 316 ----KGAVYG-GFKSKEGIPKLVADFMAKKFSL------DALITHVLPFEKINEGFDLLH 364
                 AV G      +G  +LV+  +A+  +L         I  V PFEK+ +    + 
Sbjct: 316 LLQANRAVCGFHLGYLDGEVELVSGVVARLLALYNQGHIKPHIDSVWPFEKVADAMKQMQ 375

Query: 365 SGKSIRTVL 373
             K++  VL
Sbjct: 376 EKKNVGKVL 384


>gi|67078406 trans-2-enoyl-CoA reductase, mitochondrial isoform b
           [Homo sapiens]
          Length = 297

 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 53/226 (23%), Positives = 84/226 (37%), Gaps = 56/226 (24%)

Query: 41  MVAVGICHTDDHVVSGN--LVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQC 98
           M+A  I  +D +++ GN   +  LP + G+E    V +VG  VT +KPGD VIP      
Sbjct: 1   MLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSNVTGLKPGDWVIPANA--- 57

Query: 99  GKCRVCKNPESNYCLKNDLGNPRGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAV 158
                                                       G  T+    V  E A+
Sbjct: 58  --------------------------------------------GLGTWRTEAVFSEEAL 73

Query: 159 AKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPG-STCAVFGLGGVGLSAVMGCKAAGA 217
            ++ +  PL+    +G    T Y   ++  ++ PG S        GVG + +    A G 
Sbjct: 74  IQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGL 133

Query: 218 ARIIAV----DINKDKFAKAKELGATECINPQDYKKP-IQEVLKEM 258
             I  V    DI K    + K LGA   I  ++ ++P ++   K+M
Sbjct: 134 RTINVVRDRPDIQK-LSDRLKSLGAEHVITEEELRRPEMKNFFKDM 178


>gi|28557745 zinc binding alcohol dehydrogenase domain containing 2
           [Homo sapiens]
          Length = 377

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 39/133 (29%), Positives = 63/133 (47%), Gaps = 8/133 (6%)

Query: 141 FLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFG 200
           ++   +F++YTVV  +    + +  P E + L+  G +T Y S   +  ++ G    V  
Sbjct: 123 YMAPGSFAEYTVVPASIATPVPSVKP-EYLTLLVSG-TTAYISLKELGGLSEGKKVLVTA 180

Query: 201 L-GGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYK-KPIQEVLKEM 258
             GG G  A+   K A    +I    + +K A  K LG   C  P +YK +P+  VLK+ 
Sbjct: 181 AAGGTGQFAMQLSKKA-KCHVIGTCSSDEKSAFLKSLG---CDRPINYKTEPVGTVLKQE 236

Query: 259 TDGGVDFSFEVIG 271
              GVD  +E +G
Sbjct: 237 YPEGVDVVYESVG 249


>gi|24308257 vesicle amine transport protein 1 homolog (T.
           californica)-like [Homo sapiens]
          Length = 419

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 27/88 (30%), Positives = 46/88 (52%), Gaps = 2/88 (2%)

Query: 32  PKAYEVRIKMVAVGICHTDDHVVSGNLVTP--LPVILGHEAAGIVESVGEGVTTVKPGDK 89
           P+  E++I++ A G+   D  V  GN+  P   P++ G E +GIVE++G+ V   + GD+
Sbjct: 66  PQDGELKIRVKACGLNFIDLMVRQGNIDNPPKTPLVPGFECSGIVEALGDSVKGYEIGDR 125

Query: 90  VIPLFTPQCGKCRVCKNPESNYCLKNDL 117
           V+           VC   E  Y + +D+
Sbjct: 126 VMAFVNYNAWAEVVCTPVEFVYKIPDDM 153


>gi|41872631 fatty acid synthase [Homo sapiens]
          Length = 2511

 Score = 37.4 bits (85), Expect = 0.022
 Identities = 42/161 (26%), Positives = 67/161 (41%), Gaps = 7/161 (4%)

Query: 167  LEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVF-GLGGVGLSAVMGCKAAGAARIIAV-D 224
            LE+   +   +ST Y + V   +V PG T  +  G GGVG +A+    + G      V  
Sbjct: 1642 LEEAASVPVVYSTAYYALVVRGRVRPGETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGS 1701

Query: 225  INKDKFAKAK--ELGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLC 282
              K  + +A+  +L +T   N +D     Q VL      GVD     +   + + AS+ C
Sbjct: 1702 AEKRAYLQARFPQLDSTSFANSRDTSFE-QHVLWHTGGKGVDLVLNSLAE-EKLQASVRC 1759

Query: 283  CHEACGTSVIVGVPPASQNLSINPMLLLTGRTWKGAVYGGF 323
                 G  + +G    SQN  +   + L   T+ G +   F
Sbjct: 1760 L-ATHGRFLEIGKFDLSQNHPLGMAIFLKNVTFHGVLLDAF 1799


>gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens]
          Length = 332

 Score = 37.0 bits (84), Expect = 0.029
 Identities = 36/127 (28%), Positives = 52/127 (40%), Gaps = 7/127 (5%)

Query: 148 SQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVF-GLGGVGL 206
           +QY  V E  +  I     L +   I   + T +     V  V  G    +  GL GVG 
Sbjct: 96  AQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGT 155

Query: 207 SAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP--IQEVLKEMTDGGVD 264
           +A+   + AGA  ++     K K   A++LGA    N   YKK    +  LK     GV+
Sbjct: 156 AAIQLTRMAGAIPLVTAGSQK-KLQMAEKLGAAAGFN---YKKEDFSEATLKFTKGAGVN 211

Query: 265 FSFEVIG 271
              + IG
Sbjct: 212 LILDCIG 218


>gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens]
          Length = 332

 Score = 37.0 bits (84), Expect = 0.029
 Identities = 36/127 (28%), Positives = 52/127 (40%), Gaps = 7/127 (5%)

Query: 148 SQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVNVAKVTPGSTCAVF-GLGGVGL 206
           +QY  V E  +  I     L +   I   + T +     V  V  G    +  GL GVG 
Sbjct: 96  AQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGT 155

Query: 207 SAVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP--IQEVLKEMTDGGVD 264
           +A+   + AGA  ++     K K   A++LGA    N   YKK    +  LK     GV+
Sbjct: 156 AAIQLTRMAGAIPLVTAGSQK-KLQMAEKLGAAAGFN---YKKEDFSEATLKFTKGAGVN 211

Query: 265 FSFEVIG 271
              + IG
Sbjct: 212 LILDCIG 218


>gi|90669511 crystallin, zeta-like 1 [Homo sapiens]
          Length = 349

 Score = 35.0 bits (79), Expect = 0.11
 Identities = 44/162 (27%), Positives = 68/162 (41%), Gaps = 18/162 (11%)

Query: 66  LGHEAAGIVESVGEGVTTVKPGDKVI---PLFTPQCGKCRVCKNPESNYCLKND---LGN 119
           +G E AGIV  VG  V+  +P D+V+   PL +   G C V +  E     K +      
Sbjct: 62  VGREIAGIVLDVGSKVSFFQPDDEVVGILPLDSEDPGLCEVVRVHEHYLVHKPEKVTWTE 121

Query: 120 PRGTLQDGTRRFTC--------RGKPIHHFLGTSTFSQYTV-VDENAVAKI--DAASPLE 168
             G+++DG R +T          GK +    G S F    + +  +  AK+   A S  +
Sbjct: 122 AAGSIRDGVRAYTALHYLSHLSPGKSVLIMDGASAFGTIAIQLAHHRGAKVISTACSLED 181

Query: 169 KVCLIGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVM 210
           K CL            V+  KV    +C +   GG+G+  V+
Sbjct: 182 KQCLERFRPPIARVIDVSNGKVHVAESC-LEETGGLGVDIVL 222


>gi|169203160 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 638

 Score = 32.3 bits (72), Expect = 0.71
 Identities = 22/108 (20%), Positives = 51/108 (47%), Gaps = 9/108 (8%)

Query: 6   KVIKCKAAVLWEVKKPFSIED------VEVAPPKAY--EVRIKMVAVGICHTDDHVVSGN 57
           ++++ ++  LW+ ++  ++ D       E   P  +  ++ ++  A+G+ H  +H+ S  
Sbjct: 323 RILQPESYELWKHRQDLTVVDYMEPRVAESQEPSNWREDIALRRAALGLRHLRNHITSCP 382

Query: 58  LVTPLPVILGHEAAGIVESV-GEGVTTVKPGDKVIPLFTPQCGKCRVC 104
             T  P +  +   G  ++V G  +  ++    V+P  T + G CR C
Sbjct: 383 TRTVAPRLCYNPKGGGTDAVPGSAIQALETSAWVLPPSTGRWGPCRGC 430


>gi|169203656 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 638

 Score = 32.3 bits (72), Expect = 0.71
 Identities = 22/108 (20%), Positives = 51/108 (47%), Gaps = 9/108 (8%)

Query: 6   KVIKCKAAVLWEVKKPFSIED------VEVAPPKAY--EVRIKMVAVGICHTDDHVVSGN 57
           ++++ ++  LW+ ++  ++ D       E   P  +  ++ ++  A+G+ H  +H+ S  
Sbjct: 323 RILQPESYELWKHRQDLTVVDYMEPRVAESQEPSNWREDIALRRAALGLRHLRNHITSCP 382

Query: 58  LVTPLPVILGHEAAGIVESV-GEGVTTVKPGDKVIPLFTPQCGKCRVC 104
             T  P +  +   G  ++V G  +  ++    V+P  T + G CR C
Sbjct: 383 TRTVAPRLCYNPKGGGTDAVPGSAIQALETSAWVLPPSTGRWGPCRGC 430


>gi|169202387 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 638

 Score = 32.3 bits (72), Expect = 0.71
 Identities = 22/108 (20%), Positives = 51/108 (47%), Gaps = 9/108 (8%)

Query: 6   KVIKCKAAVLWEVKKPFSIED------VEVAPPKAY--EVRIKMVAVGICHTDDHVVSGN 57
           ++++ ++  LW+ ++  ++ D       E   P  +  ++ ++  A+G+ H  +H+ S  
Sbjct: 323 RILQPESYELWKHRQDLTVVDYMEPRVAESQEPSNWREDIALRRAALGLRHLRNHITSCP 382

Query: 58  LVTPLPVILGHEAAGIVESV-GEGVTTVKPGDKVIPLFTPQCGKCRVC 104
             T  P +  +   G  ++V G  +  ++    V+P  T + G CR C
Sbjct: 383 TRTVAPRLCYNPKGGGTDAVPGSAIQALETSAWVLPPSTGRWGPCRGC 430


>gi|226059159 prostaglandin reductase 1 isoform 1 [Homo sapiens]
          Length = 329

 Score = 29.6 bits (65), Expect = 4.6
 Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 17/107 (15%)

Query: 173 IGCGFSTGYGSAVNVAKVTPGSTCAV-FGLGGVG-----LSAVMGCKAAGAARIIAVDIN 226
           +G    T Y   + +  V  G T  V    G VG     ++ + GCK  GA        +
Sbjct: 122 VGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVG------S 175

Query: 227 KDKFAKAKELGATECINPQDYK--KPIQEVLKEMTDGGVDFSFEVIG 271
            +K A  ++LG     N   YK  + ++E LK+ +  G D  F+ +G
Sbjct: 176 DEKVAYLQKLGFDVVFN---YKTVESLEETLKKASPDGYDCYFDNVG 219


>gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens]
          Length = 329

 Score = 29.6 bits (65), Expect = 4.6
 Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 17/107 (15%)

Query: 173 IGCGFSTGYGSAVNVAKVTPGSTCAV-FGLGGVG-----LSAVMGCKAAGAARIIAVDIN 226
           +G    T Y   + +  V  G T  V    G VG     ++ + GCK  GA        +
Sbjct: 122 VGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVG------S 175

Query: 227 KDKFAKAKELGATECINPQDYK--KPIQEVLKEMTDGGVDFSFEVIG 271
            +K A  ++LG     N   YK  + ++E LK+ +  G D  F+ +G
Sbjct: 176 DEKVAYLQKLGFDVVFN---YKTVESLEETLKKASPDGYDCYFDNVG 219


>gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens]
          Length = 301

 Score = 29.6 bits (65), Expect = 4.6
 Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 17/107 (15%)

Query: 173 IGCGFSTGYGSAVNVAKVTPGSTCAV-FGLGGVG-----LSAVMGCKAAGAARIIAVDIN 226
           +G    T Y   + +  V  G T  V    G VG     ++ + GCK  GA        +
Sbjct: 122 VGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVG------S 175

Query: 227 KDKFAKAKELGATECINPQDYK--KPIQEVLKEMTDGGVDFSFEVIG 271
            +K A  ++LG     N   YK  + ++E LK+ +  G D  F+ +G
Sbjct: 176 DEKVAYLQKLGFDVVFN---YKTVESLEETLKKASPDGYDCYFDNVG 219


>gi|56788377 nucleoporin like 1 isoform b [Homo sapiens]
          Length = 587

 Score = 29.6 bits (65), Expect = 4.6
 Identities = 15/46 (32%), Positives = 22/46 (47%), Gaps = 2/46 (4%)

Query: 173 IGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAA 218
           +G  F T +GS +     + G   +   LGG G S+  GC   GA+
Sbjct: 472 LGVSFGTPFGSGIGTGLQSSGLGSS--NLGGFGTSSGFGCSTTGAS 515


>gi|30102928 nucleoporin like 1 isoform a [Homo sapiens]
          Length = 599

 Score = 29.6 bits (65), Expect = 4.6
 Identities = 15/46 (32%), Positives = 22/46 (47%), Gaps = 2/46 (4%)

Query: 173 IGCGFSTGYGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAA 218
           +G  F T +GS +     + G   +   LGG G S+  GC   GA+
Sbjct: 484 LGVSFGTPFGSGIGTGLQSSGLGSS--NLGGFGTSSGFGCSTTGAS 527


>gi|194018457 N-acetylgalactosaminyltransferase-like 6 [Homo
           sapiens]
          Length = 601

 Score = 29.3 bits (64), Expect = 6.0
 Identities = 20/57 (35%), Positives = 26/57 (45%), Gaps = 10/57 (17%)

Query: 6   KVIKCK------AAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICHTDDHVVSG 56
           K +KCK      AAV W+V K +      V PP A    I+ VA  +C    H  +G
Sbjct: 423 KQLKCKDFKWFMAAVAWDVPKYYP----PVEPPPAAWGEIRNVAANLCVDSKHGATG 475


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,518,537
Number of Sequences: 37866
Number of extensions: 643725
Number of successful extensions: 1478
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 1446
Number of HSP's gapped (non-prelim): 40
length of query: 375
length of database: 18,247,518
effective HSP length: 104
effective length of query: 271
effective length of database: 14,309,454
effective search space: 3877862034
effective search space used: 3877862034
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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