Guide to the Human Genome
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Search of human proteins with 34335266

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo
sapiens]
         (1160 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo ...  2341   0.0  
gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo ...  2322   0.0  
gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo ...  2274   0.0  
gi|238814389 zinc finger, MYND domain containing 11 isoform a [H...   186   1e-46
gi|238814385 zinc finger, MYND domain containing 11 isoform a [H...   186   1e-46
gi|238814387 zinc finger, MYND domain containing 11 isoform b [H...   182   2e-45
gi|47419911 transcriptional intermediary factor 1 alpha isoform ...    89   2e-17
gi|47419909 transcriptional intermediary factor 1 alpha isoform ...    89   2e-17
gi|74027251 tripartite motif-containing 33 protein isoform beta ...    86   2e-16
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]    81   7e-15
gi|74027249 tripartite motif-containing 33 protein isoform alpha...    77   1e-13
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     71   5e-12
gi|209977097 tripartite motif-containing 66 [Homo sapiens]             70   9e-12
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   69   3e-11
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    69   3e-11
gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens]           68   4e-11
gi|20357585 TBP-associated factor 1 isoform 1 [Homo sapiens]           68   4e-11
gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo sa...    67   1e-10
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   65   3e-10
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   65   3e-10
gi|38788260 bromodomain PHD finger transcription factor isoform ...    65   4e-10
gi|38788274 bromodomain PHD finger transcription factor isoform ...    65   4e-10
gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa...    62   2e-09
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ...    62   3e-09
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]            60   1e-08
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]            60   1e-08
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]            60   1e-08
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]            60   1e-08
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]            60   1e-08
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]            60   1e-08

>gi|34335266 zinc finger, MYND-type containing 8 isoform b [Homo
            sapiens]
          Length = 1160

 Score = 2341 bits (6066), Expect = 0.0
 Identities = 1160/1160 (100%), Positives = 1160/1160 (100%)

Query: 1    MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 60
            MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS
Sbjct: 1    MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 60

Query: 61   PIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQV 120
            PIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQV
Sbjct: 61   PIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQV 120

Query: 121  LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF 180
            LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF
Sbjct: 121  LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF 180

Query: 181  AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI 240
            AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI
Sbjct: 181  AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI 240

Query: 241  LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL 300
            LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL
Sbjct: 241  LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL 300

Query: 301  VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN 360
            VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN
Sbjct: 301  VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN 360

Query: 361  SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN 420
            SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN
Sbjct: 361  SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN 420

Query: 421  FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS 480
            FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS
Sbjct: 421  FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS 480

Query: 481  ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL 540
            ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL
Sbjct: 481  ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL 540

Query: 541  DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV 600
            DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV
Sbjct: 541  DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV 600

Query: 601  YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN 660
            YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN
Sbjct: 601  YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN 660

Query: 661  PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT 720
            PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT
Sbjct: 661  PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT 720

Query: 721  VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET 780
            VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET
Sbjct: 721  VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET 780

Query: 781  PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN 840
            PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN
Sbjct: 781  PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN 840

Query: 841  SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 900
            SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI
Sbjct: 841  SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 900

Query: 901  AKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLE 960
            AKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLE
Sbjct: 901  AKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLE 960

Query: 961  LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC 1020
            LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC
Sbjct: 961  LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC 1020

Query: 1021 DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE 1080
            DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE
Sbjct: 1021 DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE 1080

Query: 1081 KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHN 1140
            KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHN
Sbjct: 1081 KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHN 1140

Query: 1141 TSTSTKSLLPKESRLDTFWD 1160
            TSTSTKSLLPKESRLDTFWD
Sbjct: 1141 TSTSTKSLLPKESRLDTFWD 1160


>gi|34335262 zinc finger, MYND-type containing 8 isoform a [Homo
            sapiens]
          Length = 1188

 Score = 2322 bits (6018), Expect = 0.0
 Identities = 1159/1188 (97%), Positives = 1159/1188 (97%), Gaps = 28/1188 (2%)

Query: 1    MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 60
            MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS
Sbjct: 1    MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 60

Query: 61   PIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQV 120
            PIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQV
Sbjct: 61   PIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQV 120

Query: 121  LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF 180
            LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF
Sbjct: 121  LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF 180

Query: 181  AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI 240
            AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI
Sbjct: 181  AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI 240

Query: 241  LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL 300
            LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL
Sbjct: 241  LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL 300

Query: 301  VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN 360
            VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN
Sbjct: 301  VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN 360

Query: 361  SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN 420
            SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN
Sbjct: 361  SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN 420

Query: 421  FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS 480
            FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS
Sbjct: 421  FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS 480

Query: 481  ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL 540
            ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL
Sbjct: 481  ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL 540

Query: 541  DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV 600
            DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV
Sbjct: 541  DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV 600

Query: 601  YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN 660
            YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN
Sbjct: 601  YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN 660

Query: 661  PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT 720
            PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT
Sbjct: 661  PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT 720

Query: 721  VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET 780
            VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET
Sbjct: 721  VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET 780

Query: 781  PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN 840
            PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN
Sbjct: 781  PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN 840

Query: 841  SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 900
            SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI
Sbjct: 841  SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 900

Query: 901  AKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLE 960
            AKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLE
Sbjct: 901  AKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLE 960

Query: 961  LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC 1020
            LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC
Sbjct: 961  LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC 1020

Query: 1021 DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE 1080
            DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE
Sbjct: 1021 DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE 1080

Query: 1081 KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGS------------------------- 1115
            KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGS                         
Sbjct: 1081 KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSVSKRCDKQPAYAPTTTDHQPHPNYP 1140

Query: 1116 ---DHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD 1160
                HSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD
Sbjct: 1141 AQKYHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKESRLDTFWD 1188


>gi|34335264 zinc finger, MYND-type containing 8 isoform c [Homo
            sapiens]
          Length = 1135

 Score = 2274 bits (5892), Expect = 0.0
 Identities = 1135/1160 (97%), Positives = 1135/1160 (97%), Gaps = 25/1160 (2%)

Query: 1    MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 60
            MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS
Sbjct: 1    MHPQSLAEEEIKTEQEVVEGMDISTRSKDPGSAERTAQKRKFPSPPHSSNGHSPQDTSTS 60

Query: 61   PIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRNDFYCWVCHREGQV 120
            PIKKKKKPGLLNSNNKEQ                         DGRNDFYCWVCHREGQV
Sbjct: 61   PIKKKKKPGLLNSNNKEQ-------------------------DGRNDFYCWVCHREGQV 95

Query: 121  LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF 180
            LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF
Sbjct: 96   LCCELCPRVYHAKCLRLTSEPEGDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLKF 155

Query: 181  AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI 240
            AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI
Sbjct: 156  AIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWI 215

Query: 241  LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL 300
            LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL
Sbjct: 216  LHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIEVCPECYLAACQKRDNWFCEPCSNPHPL 275

Query: 301  VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN 360
            VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN
Sbjct: 276  VWAKLKGFPFWPAKALRDKDGQVDARFFGQHDRAWVPINNCYLMSKEIPFSVKKTKSIFN 335

Query: 361  SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN 420
            SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN
Sbjct: 336  SAMQEMEVYVENIRRKFGVFNYSPFRTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLN 395

Query: 421  FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS 480
            FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS
Sbjct: 396  FDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFS 455

Query: 481  ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL 540
            ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL
Sbjct: 456  ASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNL 515

Query: 541  DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV 600
            DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV
Sbjct: 516  DRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDV 575

Query: 601  YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN 660
            YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN
Sbjct: 576  YTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN 635

Query: 661  PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT 720
            PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT
Sbjct: 636  PVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPT 695

Query: 721  VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET 780
            VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET
Sbjct: 696  VHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPET 755

Query: 781  PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN 840
            PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN
Sbjct: 756  PVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWN 815

Query: 841  SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 900
            SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI
Sbjct: 816  SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 875

Query: 901  AKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLE 960
            AKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLE
Sbjct: 876  AKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLE 935

Query: 961  LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC 1020
            LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC
Sbjct: 936  LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC 995

Query: 1021 DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE 1080
            DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE
Sbjct: 996  DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKE 1055

Query: 1081 KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHN 1140
            KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHN
Sbjct: 1056 KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHN 1115

Query: 1141 TSTSTKSLLPKESRLDTFWD 1160
            TSTSTKSLLPKESRLDTFWD
Sbjct: 1116 TSTSTKSLLPKESRLDTFWD 1135


>gi|238814389 zinc finger, MYND domain containing 11 isoform a [Homo
           sapiens]
          Length = 602

 Score =  186 bits (472), Expect = 1e-46
 Identities = 100/286 (34%), Positives = 154/286 (53%), Gaps = 23/286 (8%)

Query: 97  PVDVVPQDGRN-DFYCWVCHREGQVLCCELCPRVYHAKCL------RLTSEPEGDWFCPE 149
           P D +  +  N D+YC+ CH  G+VL C+LC RVYH+KCL      R +S P   W CP 
Sbjct: 88  PGDEIDWETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSP---WQCPV 144

Query: 150 CEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYI 209
           C  I      +           +++   L+F + +MK+   D  +K     +HP Y   +
Sbjct: 145 CRSIKKKNTNK-----------QEMGTYLRFIVSRMKERAIDLNKKGKD-NKHPMYRRLV 192

Query: 210 FHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEM 269
              +D+ T+++   +  Y   E F ADA+ +LHN +I+ G + +   IA+++ K   HE+
Sbjct: 193 HSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHEL 252

Query: 270 NEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFG 329
           +E+++C  C+  +  + DNWFC PC   H LVWAK+KGF FWPAK ++ +D QVD RFFG
Sbjct: 253 DELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFG 312

Query: 330 -QHDRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIR 374
             H RAW+P  N   ++  I     K    +  A  E+E++   +R
Sbjct: 313 HHHQRAWIPSENIQDITVNIHRLHVKRSMGWKKACDELELHQRFLR 358



 Score = 95.9 bits (237), Expect = 2e-19
 Identities = 60/206 (29%), Positives = 104/206 (50%), Gaps = 18/206 (8%)

Query: 841  SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 900
            + +V+ K+    P T  ++      + P      S+ST    ++A  P     +    + 
Sbjct: 401  NQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTND 460

Query: 901  AKYTSKMMDAIKGTMTEIYNDLS-------KNTTGSTIAE-IRRLRIEIEKLQWLHQQEL 952
                S   D      T+I+ND         K  T   + E + +LR E+E+ +   +Q +
Sbjct: 461  GVCQSMCHDKY----TKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEK---RQAV 513

Query: 953  SEMKHNLELTM-AEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIF 1011
            ++   N++  M  + +Q  E+ ++  + E+KK L  + +Q + +TKKKQWC NC++EA++
Sbjct: 514  NKAVANMQGEMDRKCKQVKEKCKEEFVEEIKK-LATQHKQLISQTKKKQWCYNCEEEAMY 572

Query: 1012 YCCWNTSYCDYPCQQAHW-PEHMKSC 1036
            +CCWNTSYC   CQQ HW  EH ++C
Sbjct: 573  HCCWNTSYCSIKCQQEHWHAEHKRTC 598


>gi|238814385 zinc finger, MYND domain containing 11 isoform a [Homo
           sapiens]
          Length = 602

 Score =  186 bits (472), Expect = 1e-46
 Identities = 100/286 (34%), Positives = 154/286 (53%), Gaps = 23/286 (8%)

Query: 97  PVDVVPQDGRN-DFYCWVCHREGQVLCCELCPRVYHAKCL------RLTSEPEGDWFCPE 149
           P D +  +  N D+YC+ CH  G+VL C+LC RVYH+KCL      R +S P   W CP 
Sbjct: 88  PGDEIDWETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSP---WQCPV 144

Query: 150 CEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYI 209
           C  I      +           +++   L+F + +MK+   D  +K     +HP Y   +
Sbjct: 145 CRSIKKKNTNK-----------QEMGTYLRFIVSRMKERAIDLNKKGKD-NKHPMYRRLV 192

Query: 210 FHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEM 269
              +D+ T+++   +  Y   E F ADA+ +LHN +I+ G + +   IA+++ K   HE+
Sbjct: 193 HSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGADSEQADIARMLYKDTCHEL 252

Query: 270 NEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFG 329
           +E+++C  C+  +  + DNWFC PC   H LVWAK+KGF FWPAK ++ +D QVD RFFG
Sbjct: 253 DELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFG 312

Query: 330 -QHDRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIR 374
             H RAW+P  N   ++  I     K    +  A  E+E++   +R
Sbjct: 313 HHHQRAWIPSENIQDITVNIHRLHVKRSMGWKKACDELELHQRFLR 358



 Score = 95.9 bits (237), Expect = 2e-19
 Identities = 60/206 (29%), Positives = 104/206 (50%), Gaps = 18/206 (8%)

Query: 841  SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 900
            + +V+ K+    P T  ++      + P      S+ST    ++A  P     +    + 
Sbjct: 401  NQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTND 460

Query: 901  AKYTSKMMDAIKGTMTEIYNDLS-------KNTTGSTIAE-IRRLRIEIEKLQWLHQQEL 952
                S   D      T+I+ND         K  T   + E + +LR E+E+ +   +Q +
Sbjct: 461  GVCQSMCHDKY----TKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEK---RQAV 513

Query: 953  SEMKHNLELTM-AEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIF 1011
            ++   N++  M  + +Q  E+ ++  + E+KK L  + +Q + +TKKKQWC NC++EA++
Sbjct: 514  NKAVANMQGEMDRKCKQVKEKCKEEFVEEIKK-LATQHKQLISQTKKKQWCYNCEEEAMY 572

Query: 1012 YCCWNTSYCDYPCQQAHW-PEHMKSC 1036
            +CCWNTSYC   CQQ HW  EH ++C
Sbjct: 573  HCCWNTSYCSIKCQQEHWHAEHKRTC 598


>gi|238814387 zinc finger, MYND domain containing 11 isoform b [Homo
           sapiens]
          Length = 567

 Score =  182 bits (462), Expect = 2e-45
 Identities = 100/286 (34%), Positives = 154/286 (53%), Gaps = 24/286 (8%)

Query: 97  PVDVVPQDGRN-DFYCWVCHREGQVLCCELCPRVYHAKCL------RLTSEPEGDWFCPE 149
           P D +  +  N D+YC+ CH  G+VL C+LC RVYH+KCL      R +S P   W CP 
Sbjct: 88  PGDEIDWETENHDWYCFECHLPGEVLICDLCFRVYHSKCLSDEFRLRDSSSP---WQCPV 144

Query: 150 CEKITVAECIETQSKAMTMLTIEQLSYLLKFAIQKMKQPGTDAFQKPVPLEQHPDYAEYI 209
           C  I      +           +++   L+F + +MK+   D  +K     +HP Y   +
Sbjct: 145 CRSIKKKNTNK-----------QEMGTYLRFIVSRMKERAIDLNKKGKD-NKHPMYRRLV 192

Query: 210 FHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEM 269
              +D+ T+++   +  Y   E F ADA+ +LHN +I+ G + +   IA+++ K   HE+
Sbjct: 193 HSAVDVPTIQEKVNEGKYRSYEEFKADAQLLLHNTVIFYGDSEQ-ADIARMLYKDTCHEL 251

Query: 270 NEIEVCPECYLAACQKRDNWFCEPCSNPHPLVWAKLKGFPFWPAKALRDKDGQVDARFFG 329
           +E+++C  C+  +  + DNWFC PC   H LVWAK+KGF FWPAK ++ +D QVD RFFG
Sbjct: 252 DELQLCKNCFYLSNARPDNWFCYPCIPNHELVWAKMKGFGFWPAKVMQKEDNQVDVRFFG 311

Query: 330 -QHDRAWVPINNCYLMSKEIPFSVKKTKSIFNSAMQEMEVYVENIR 374
             H RAW+P  N   ++  I     K    +  A  E+E++   +R
Sbjct: 312 HHHQRAWIPSENIQDITVNIHRLHVKRSMGWKKACDELELHQRFLR 357



 Score = 40.0 bits (92), Expect = 0.013
 Identities = 39/170 (22%), Positives = 76/170 (44%), Gaps = 17/170 (10%)

Query: 841  SSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADI 900
            + +V+ K+    P T  ++      + P      S+ST    ++A  P     +    + 
Sbjct: 400  NQSVEPKKEEPEPETEAVSSSQEIPTMPQPIEKVSVSTQTKKLSASSPRMLHRSTQTTND 459

Query: 901  AKYTSKMMDAIKGTMTEIYNDLS-------KNTTGSTIAE-IRRLRIEIEKLQWLHQQEL 952
                S   D      T+I+ND         K  T   + E + +LR E+E+ +   +Q +
Sbjct: 460  GVCQSMCHDKY----TKIFNDFKDRMKSDHKRETERVVREALEKLRSEMEEEK---RQAV 512

Query: 953  SEMKHNLELTM-AEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQW 1001
            ++   N++  M  + +Q  E+ ++  + E+KK L  + +Q + +TKKKQW
Sbjct: 513  NKAVANMQGEMDRKCKQVKEKCKEEFVEEIKK-LATQHKQLISQTKKKQW 561


>gi|47419911 transcriptional intermediary factor 1 alpha isoform a
           [Homo sapiens]
          Length = 1050

 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 71/236 (30%), Positives = 109/236 (46%), Gaps = 26/236 (11%)

Query: 47  HSSNGHSPQDT---STSPIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQ 103
           +SS   + ++T   S +P     +PGL   N+         P    K PL     +   +
Sbjct: 766 NSSQSSTSEETVLRSDAPDSTGDQPGLHQDNSSNGKSEWLDPS--QKSPLHVG--ETRKE 821

Query: 104 DGRNDFYCWVCHREGQVLCCELCPRVYHAKC--LRLTSEPEGDWFCPECEKITVAEC--- 158
           D  N+ +C VC   G++LCCE CP+V+H  C    LT+ P G+W C  C  ++  E    
Sbjct: 822 DDPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYD 881

Query: 159 IETQSKAMTMLTIEQLSYLLKFAIQKMKQ--------PGTDAFQKPVPLEQHPDYAEYIF 210
            +  S        E L  L     +K ++          + AFQ PVPL   PDY + I 
Sbjct: 882 CDAPSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTV-PDYYKIIK 940

Query: 211 HPMDLCTLEKNAKK--KMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKI 264
           +PMDL T++K  ++   MY   E F+AD + I  NC  +N  +   +++A   IK+
Sbjct: 941 NPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPD---SEVANAGIKL 993


>gi|47419909 transcriptional intermediary factor 1 alpha isoform b
           [Homo sapiens]
          Length = 1016

 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 71/236 (30%), Positives = 109/236 (46%), Gaps = 26/236 (11%)

Query: 47  HSSNGHSPQDT---STSPIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQ 103
           +SS   + ++T   S +P     +PGL   N+         P    K PL     +   +
Sbjct: 732 NSSQSSTSEETVLRSDAPDSTGDQPGLHQDNSSNGKSEWLDPS--QKSPLHVG--ETRKE 787

Query: 104 DGRNDFYCWVCHREGQVLCCELCPRVYHAKC--LRLTSEPEGDWFCPECEKITVAEC--- 158
           D  N+ +C VC   G++LCCE CP+V+H  C    LT+ P G+W C  C  ++  E    
Sbjct: 788 DDPNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDLSKPEVEYD 847

Query: 159 IETQSKAMTMLTIEQLSYLLKFAIQKMKQ--------PGTDAFQKPVPLEQHPDYAEYIF 210
            +  S        E L  L     +K ++          + AFQ PVPL   PDY + I 
Sbjct: 848 CDAPSHNSEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTV-PDYYKIIK 906

Query: 211 HPMDLCTLEKNAKK--KMYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKI 264
           +PMDL T++K  ++   MY   E F+AD + I  NC  +N  +   +++A   IK+
Sbjct: 907 NPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPD---SEVANAGIKL 959


>gi|74027251 tripartite motif-containing 33 protein isoform beta [Homo
            sapiens]
          Length = 1110

 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 57/182 (31%), Positives = 84/182 (46%), Gaps = 14/182 (7%)

Query: 104  DGRNDFYCWVCHREGQVLCCELCPRVYHAKCL--RLTSEPEGDWFCPECEKITVAEC--- 158
            D  N+ +C VC   G +LCCE CP+V+H  C    L S P GDW C  C  I   E    
Sbjct: 883  DDPNEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRDIGKPEVEYD 942

Query: 159  ---IETQSKAMTMLTIEQLSYLL--KFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPM 213
               ++   K  T   +  +      +  +       +  FQ+PVP    P+Y + I  PM
Sbjct: 943  CDNLQHSKKGKTAQGLSPVDQRKCERLLLYLYCHELSIEFQEPVPASI-PNYYKIIKKPM 1001

Query: 214  DLCTLEKNAKKKM---YGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMN 270
            DL T++K  +KK    Y   + F+AD + I  NC  +N  + ++ Q  K V    E ++ 
Sbjct: 1002 DLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFNEADSEVAQAGKAVALYFEDKLT 1061

Query: 271  EI 272
            EI
Sbjct: 1062 EI 1063


>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
          Length = 1301

 Score = 80.9 bits (198), Expect = 7e-15
 Identities = 127/702 (18%), Positives = 255/702 (36%), Gaps = 14/702 (1%)

Query: 447  SDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS 506
            SD   S  S +S   +    + D+   + SS  S S +S D  D S +S + + + ++ S
Sbjct: 572  SDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSES 631

Query: 507  LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLI 566
             S      S    +  +  +D + ++ S  + N   S    D  + S S    ++     
Sbjct: 632  DSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSD 691

Query: 567  SPKRQIRSRFQLNLDKT-IESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISD 625
            S      S    + D +  +S  +    N  S D  ++     S+ S  SDSSDS   S+
Sbjct: 692  SSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSN 751

Query: 626  DEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKD 685
                S +             D   S+       +N      +   +S +S+ ++     D
Sbjct: 752  SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSD 811

Query: 686  KASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGRE 745
             +        +     +     D     D +DS     G DSDS +        D S   
Sbjct: 812  SSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSS 871

Query: 746  GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTV 805
               N  +  + S   +    +  S +  S     +     S +  S+  + ++ S++S+ 
Sbjct: 872  DSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSD 931

Query: 806  TVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQ 865
               +   + +             +++        +S +    + + S S+ +     S+ 
Sbjct: 932  NSNSSDSSNSSDSSDSSDSSNSSDSSN-------SSDSSNSSDSSDSNSSDSSDSSNSSD 984

Query: 866  SSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKN 925
            SS    SS S  +  SS ++D   ++ S+D  +  +  +S   D+   + +   +D S +
Sbjct: 985  SSDSSDSSDSSDSSDSSNSSDSSDSSDSSD--SSNSSDSSNSSDSSNSSDSSDSSDSSDS 1042

Query: 926  TTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELT-MAEMRQSLEQERDRLIAEVKKQ 984
            +  S  ++        +        + S+   + + +  +E   S +       ++    
Sbjct: 1043 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDS 1102

Query: 985  LELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQ 1044
             +        ++      +N    +      ++S        +   E   S   S ++  
Sbjct: 1103 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDS 1162

Query: 1045 QE-ADAEVNTETLNKS-SQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRE 1102
             + +D+  ++++ + S S  SS S+ S+ S  +S S +   S++ S  S S+     S  
Sbjct: 1163 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1222

Query: 1103 TPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTS 1144
            + SS    SN+ SD S S+ SS  SS+    S  SD + STS
Sbjct: 1223 SDSSDSSDSNESSDSSDSSDSS-DSSNSSDSSDSSDSSDSTS 1263



 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 131/700 (18%), Positives = 258/700 (36%), Gaps = 42/700 (6%)

Query: 455  STNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSGSPKPF 514
            S++S+  + SD        ++ S  S S  S D  D S +S +S  +  + S S S K  
Sbjct: 571  SSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSE 630

Query: 515  SPQLSAPITTKTDKTSTTGSILNLNLDRSKAE-----MDLKELSESVQQQSTPVPLISPK 569
            S   S+   +K+D + +  S  + N D S +       D  + S+S    S+     S  
Sbjct: 631  SD--SSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSD 688

Query: 570  RQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQK 629
                S    + + +  S  +    ++ S+   +    SDS+ S  SDSSDS   SD    
Sbjct: 689  SSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNS--NSSDSDSSNSSDSSDSSNSSDSSDS 746

Query: 630  SKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASP 689
            S +             +   S+       ++      +   +S +S+ +D     D ++ 
Sbjct: 747  SDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNS 806

Query: 690  EPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKN 749
                D S+ +        D     D +DS       DS   S+       D S R    N
Sbjct: 807  SDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSD---GSDSDSSNRSDSSN 863

Query: 750  KKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTA 809
              +  + S   +    +  S +  S +  ++   + SS   S+  + ++ S+ S+ +  +
Sbjct: 864  SSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDS 923

Query: 810  PAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPL 869
               + +             +++ +      +S++      + S ++S  +   S+ SS  
Sbjct: 924  SESSNSSDNSNSSDSSNSSDSSDSSD----SSNSSDSSNSSDSSNSSDSSDSNSSDSSDS 979

Query: 870  VTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGS 929
              SS S  +  SS ++D   ++ S+D     +  +S   D+   + +   +D S ++  S
Sbjct: 980  SNSSDSSDSSDSSDSSDSSDSSNSSD-----SSDSSDSSDSSNSSDSSNSSDSSNSSDSS 1034

Query: 930  TIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEK 989
              ++                 + S+   + + + +          D   ++     +   
Sbjct: 1035 DSSD---------------SSDSSDSSDSSDSSDSSNSSDSSDSSDS--SDSSDSSDSSD 1077

Query: 990  QQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADA 1049
                 E+      +N    +      ++S        +   +   S   S ++   ++  
Sbjct: 1078 SSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1137

Query: 1050 EVNTETLNKSSQGSSSS--TQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSI 1107
              N+   + SS+ S SS  + S+ S  +S S +   S++ S  S S+     S  + SS 
Sbjct: 1138 SSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSD 1197

Query: 1108 LLGSNQGSDHSRSNKSSWSS--SDEKRGSTRSDHNTSTST 1145
               S+  SD S S+ SS SS  SD    S  SD N S+ +
Sbjct: 1198 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDS 1237



 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 129/706 (18%), Positives = 258/706 (36%), Gaps = 65/706 (9%)

Query: 447  SDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS 506
            SD   S  S+NSS  + S    D+   ++SS  S S +S D  D S +S +S  +  + S
Sbjct: 651  SDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDS 710

Query: 507  LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAE--MDLKELSESVQQQSTPVP 564
             S      S   S+   +     S+  S  + + D S +    D  + S+S     +   
Sbjct: 711  DSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDS 770

Query: 565  LISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYIS 624
              S      S    + D +  S  +    +  S +   + + SDS DS+ S+SSDS   S
Sbjct: 771  SDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSS 830

Query: 625  D--DEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGA 682
            D  D   S +  + ++  +G   D    +       ++          +S +S  +D   
Sbjct: 831  DSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSS---------DSSDSSNSSDSSD 881

Query: 683  VKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHS 742
              D        D S+ +  S     D     D +DS       +S + S        D+S
Sbjct: 882  SSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSS--------DNS 933

Query: 743  GREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTS 802
                  N  +  + S   +        ++  S+S   +     S + +S +  ++ +S S
Sbjct: 934  NSSDSSNSSDSSDSSDSSN--------SSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDS 985

Query: 803  STVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVT 862
            S  + ++ +  ++ S                      NSS       +   S S+     
Sbjct: 986  SDSSDSSDSSDSSDSS---------------------NSSDSSDSSDSSDSSNSS----D 1020

Query: 863  STQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDL 922
            S+ SS    SS S  +  SS ++D   ++ S+D     +  +S   D+   + +   +D 
Sbjct: 1021 SSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD-----SSNSSDSSDSSDSSDSSDSSDS 1075

Query: 923  SKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVK 982
            S ++  S  ++        +        + S+   + + + +    +     D   ++  
Sbjct: 1076 SDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS--SDSS 1133

Query: 983  KQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATA 1042
               +        ++ +    ++    +      ++S        ++  +   S   S ++
Sbjct: 1134 DSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1193

Query: 1043 PQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETS----AEKSKESGSTLDLS 1098
               ++    ++   + SS  S SS  S  S+++ +S   E+S    +  S +S ++ D S
Sbjct: 1194 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSS 1253

Query: 1099 GSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTS 1144
             S ++  S    +++    S+S   + + SD    S  SD N STS
Sbjct: 1254 DSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTS 1299



 Score = 70.5 bits (171), Expect = 9e-12
 Identities = 99/546 (18%), Positives = 203/546 (37%), Gaps = 30/546 (5%)

Query: 607  SDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKE 666
            SDS DS+ SDSS+S   SD      ++   + D +    D   S+       +N  +  +
Sbjct: 547  SDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSD 606

Query: 667  ELKSTSPASEKADPGAVKDKASPEPE-KDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGL 725
               S+  +       +  D +  E +  D   K+  S     D     D +DS       
Sbjct: 607  SSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSS 666

Query: 726  DSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTR 785
            DS   S+       D S      N  +  + S   +    +  S +  S S   +     
Sbjct: 667  DSSDSSD-----SSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNS 721

Query: 786  SSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQ 845
            +S+ + ++ ++ ++ +S++   +  + ++  S                      ++S+  
Sbjct: 722  NSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS--------------SNSSDS 767

Query: 846  QKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTS 905
                  S S+ +     S  SS    SS S ++  SS ++D   ++ S+D  +  +  +S
Sbjct: 768  SDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSS 827

Query: 906  KMMDAIKGTMTEIYNDLSKNTTGSTIAEIRR-----LRIEIEKLQWLHQQELSEMKHNLE 960
               D+   + +   +D S ++ GS      R          +     +  + S+   + E
Sbjct: 828  NSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNE 887

Query: 961  LTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYC 1020
             + +          D   ++     +        ++ +    +N    +      N+S  
Sbjct: 888  SSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSES---SNSSDNSNSSDSSNSSDS 944

Query: 1021 DYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKS-SQGSSSSTQSAPSETASASK 1079
                  ++  +   S   S ++   ++++  ++++ N S S  SS S+ S+ S  +S S 
Sbjct: 945  SDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSS 1004

Query: 1080 EKETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDH 1139
            +   S++ S  S S+   + S  + SS    S+  SD S S+ SS  SSD    S  SD 
Sbjct: 1005 DSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSS-DSSDSSNSSDSSDS 1063

Query: 1140 NTSTST 1145
            + S+ +
Sbjct: 1064 SDSSDS 1069



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 104/563 (18%), Positives = 206/563 (36%), Gaps = 44/563 (7%)

Query: 588  KAQLGINEISEDVYTAVEHSDSE-DSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMD 646
            K+  G +  S D     + ++SE D+  S   D+ Y SD+ + + N      D +G + D
Sbjct: 458  KSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNG----SDSKGAEDD 513

Query: 647  KEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPI 706
               S        TN  +      + +  ++K+D G  K  +S     D S  +  S    
Sbjct: 514  DSDST-----SDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSD 568

Query: 707  KDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGR--KNKKEPKEPSPKQDVVG 764
             D       +DS +     DSDS      D  +  +  +     +  +  + S   D   
Sbjct: 569  SDSSDSNSSSDSDSS----DSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKS 624

Query: 765  KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRP 824
             +  S +  S S  ++     +S+ +S    ++ +S SS  + ++ +  ++ S       
Sbjct: 625  DSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSS 684

Query: 825  LLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVN 884
                           NSS       + + S S+     S+ SS   +S  S S+  +S +
Sbjct: 685  ---------------NSSDSSDSSDSSNSSESS----DSSDSSDSDSSDSSDSSNSNSSD 725

Query: 885  ADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKL 944
            +D   ++ S+D        +S   D+   + +   +D S ++  S  ++        +  
Sbjct: 726  SDSSNSSDSSD--------SSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSS 777

Query: 945  QWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCAN 1004
               +  + ++  ++ + + +          D   +      +         +      +N
Sbjct: 778  DSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSN 837

Query: 1005 CKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSS 1064
                +      + S  D   +         S +  ++     +D+  + E+ N S    S
Sbjct: 838  SSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDS 897

Query: 1065 SSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSS 1124
            S++  + S  +S S +   S+  S  S S+     S  + SS    S+  SD S S+ SS
Sbjct: 898  SNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSS 957

Query: 1125 WSSSDEKRGSTRSDHNTSTSTKS 1147
             +SSD    S  SD N+S S+ S
Sbjct: 958  -NSSDSSNSSDSSDSNSSDSSDS 979



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 26/115 (22%), Positives = 53/115 (46%), Gaps = 15/115 (13%)

Query: 1048 DAEVNTETLNKSSQGSSSSTQSAPSETASASK-EKETSAEKSKESGSTLDLSGSRETPSS 1106
            D  +  +  N S + + +   ++ S+  S+S+ +   ++++SK++G+  D  G+ +  S 
Sbjct: 457  DKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSD 516

Query: 1107 ILL----------GSNQGSDHSRSN----KSSWSSSDEKRGSTRSDHNTSTSTKS 1147
                         G+N   D+ +S+    KS  S SD    S  SD + S+ + S
Sbjct: 517  STSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDS 571


>gi|74027249 tripartite motif-containing 33 protein isoform alpha
            [Homo sapiens]
          Length = 1127

 Score = 77.0 bits (188), Expect = 1e-13
 Identities = 51/158 (32%), Positives = 73/158 (46%), Gaps = 14/158 (8%)

Query: 104  DGRNDFYCWVCHREGQVLCCELCPRVYHAKCL--RLTSEPEGDWFCPECEKITVAEC--- 158
            D  N+ +C VC   G +LCCE CP+V+H  C    L S P GDW C  C  I   E    
Sbjct: 883  DDPNEDWCAVCQNGGDLLCCEKCPKVFHLTCHVPTLLSFPSGDWICTFCRDIGKPEVEYD 942

Query: 159  ---IETQSKAMTMLTIEQLSYLL--KFAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPM 213
               ++   K  T   +  +      +  +       +  FQ+PVP    P+Y + I  PM
Sbjct: 943  CDNLQHSKKGKTAQGLSPVDQRKCERLLLYLYCHELSIEFQEPVPASI-PNYYKIIKKPM 1001

Query: 214  DLCTLEKNAKKK---MYGCTEAFLADAKWILHNCIIYN 248
            DL T++K  +KK    Y   + F+AD + I  NC  +N
Sbjct: 1002 DLSTVKKKLQKKHSQHYQIPDDFVADVRLIFKNCERFN 1039


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 71.2 bits (173), Expect = 5e-12
 Identities = 124/605 (20%), Positives = 229/605 (37%), Gaps = 66/605 (10%)

Query: 563  VPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEY 622
            +P +S   +++S  ++ + +  E  K  + + E +E+     E ++ E+ E  +    E 
Sbjct: 429  IPSVSTHIKVKSEEKIKVVEKSE--KETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEE 486

Query: 623  ISDDEQKSKNEPEDTED---KEGCQMDKE-----------PSAVK--KKPKPTNPVEIKE 666
               +E++++   E+T+    +E    +KE           P+  K  +K +  +P E+K 
Sbjct: 487  EGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKS 546

Query: 667  ELKSTSPASEKADPGAVKDKASPE---PEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHL 723
              K+ SPA E+A       K+ PE   PEK+ ++       P K K   K+E  SP    
Sbjct: 547  PEKAKSPAKEEA-------KSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPA--- 596

Query: 724  GLDSDSESELVIDLGEDHSGREGRKN--KKEPKEPSP-KQDVVGKTPPSTTVGSHSPPET 780
              ++ S  +    + E+       K+  K+E K P+  K     K+P      S    ++
Sbjct: 597  --EAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKS 654

Query: 781  PVLTRSSAQTSA-----AGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQ 835
            P    + +   A     A A +     S V   A +P    SPVK++     K  +P  +
Sbjct: 655  PEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKE 714

Query: 836  RVVWNSSTVQQ-KEITQSPSTSTITLVTSTQSSPLVTSSGSMSTL-VSSVNADLPIATAS 893
                        KE  ++P  +   +    +S     S     TL V S  A  P   A 
Sbjct: 715  EAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTP---AK 771

Query: 894  ADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRL-RIEIEKLQWLHQQEL 952
             +  +   K+  K    +K  +       S     S + E  +    EI K + +     
Sbjct: 772  EEARSPADKFPEKAKSPVKEEVK------SPEKAKSPLKEDAKAPEKEIPKKEEVKSPVK 825

Query: 953  SEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFY 1012
             E K   E+ + E  +  E+E+     + +++ + +K++A  +   K      K+ A+  
Sbjct: 826  EEEKPQ-EVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVE- 883

Query: 1013 CCWNTSYCDYPCQQAHWPEHMKSCTQSATAP-----QQEADAEVNTETLNKSSQGSSSST 1067
                        ++    +  K  T    AP     +++A  +  TE   K    + +  
Sbjct: 884  ---KPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKE 940

Query: 1068 QSAPSETASASKE-KETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWS 1126
             S P+E   A+ E K+T  EK+K+           +     L  S + S          S
Sbjct: 941  PSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTL--SKEPSKPKAEKAEKSS 998

Query: 1127 SSDEK 1131
            S+D+K
Sbjct: 999  STDQK 1003



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 70/399 (17%), Positives = 147/399 (36%), Gaps = 39/399 (9%)

Query: 401 PTNPSAGT-AKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRISLSDMPRSPMSTNSS 459
           P  PS  T  K+  +EK+K+  + +    +++ +          ++  +   +       
Sbjct: 427 PKIPSVSTHIKVKSEEKIKV-VEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKE 485

Query: 460 VHTGSDVEQDAEKKATSSH-----FSASEESMDFLDKSTASPASTKT---------GQAG 505
              G + E +  ++ T S       S  +E+   + +   SPA  K+          +  
Sbjct: 486 EEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVK 545

Query: 506 SLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPL 565
           S   +  P   +  +P   K+ +     S   +     KA+   KE ++S  +  +P   
Sbjct: 546 SPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVK-SPEKAKSPAKEEAKSPAEAKSPEKA 604

Query: 566 ISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISD 625
            SP ++             E  K+   +   S +   +    +++  EK+ S + E    
Sbjct: 605 KSPVKEEAKSPAEAKSPVKEEAKSPAEVK--SPEKAKSPTKEEAKSPEKAKSPEKE---- 658

Query: 626 DEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVE--IKEELKSTSPASEKADPGAV 683
            E KS  + +     E    +K  S VK + K     +  +KEE KS   A       A 
Sbjct: 659 -EAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAK 717

Query: 684 KDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSG 743
             + +  P K+ ++  + +  P+K++ K  ++  SP          E    +D+    + 
Sbjct: 718 SPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSP----------EKAKTLDVKSPEAK 767

Query: 744 REGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPV 782
              ++  + P +  P++    K+P    V S    ++P+
Sbjct: 768 TPAKEEARSPADKFPEK---AKSPVKEEVKSPEKAKSPL 803



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 64/324 (19%), Positives = 123/324 (37%), Gaps = 17/324 (5%)

Query: 451 RSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSGS 510
           +SP    S     S  +++A+  A +    + E++   + +   SPA  K+         
Sbjct: 573 KSPAEVKSPEKAKSPAKEEAKSPAEAK---SPEKAKSPVKEEAKSPAEAKSPVKEEAKSP 629

Query: 511 PKPFSPQLSAPITTKTDKTSTTGSILNLNLDRS--KAEMDLKELSESVQQQSTPVPLISP 568
            +  SP+ +   T +  K+            +S  KA+  +K  ++S ++  +PV   + 
Sbjct: 630 AEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAK 689

Query: 569 KRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQ 628
             +          K+ E  K+ +     S +   +    +++  EK+ S   E     E+
Sbjct: 690 SPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEK 749

Query: 629 KSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKAS 688
               E   T D +  +         + P    P + K  +K    + EKA     +D  +
Sbjct: 750 AKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKA 809

Query: 689 PE---PEKD-----FSEKAKPSPHPIKDKLKGKDETDSP-TVHLGLDSDSESELVIDLGE 739
           PE   P+K+       E+ KP    +K+  K  +E  +P T       DS+ E   +  +
Sbjct: 810 PEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKE---EAPK 866

Query: 740 DHSGREGRKNKKEPKEPSPKQDVV 763
             + +   + KKEP    PK+  V
Sbjct: 867 KEAPKPKVEEKKEPAVEKPKESKV 890



 Score = 38.1 bits (87), Expect = 0.049
 Identities = 70/322 (21%), Positives = 123/322 (38%), Gaps = 25/322 (7%)

Query: 451  RSPMSTNSSVH----TGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS 506
            +SP    S V     T    +   +++A S   + S E    LD    SP +    +  +
Sbjct: 717  KSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLD--VKSPEAKTPAKEEA 774

Query: 507  LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSES-VQQQSTP--V 563
             S + K F  +  +P+  +        S L  +    + E+  KE  +S V+++  P  V
Sbjct: 775  RSPADK-FPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEV 833

Query: 564  PLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYI 623
             +  P ++          KT E   ++       E     VE       EK   S  E  
Sbjct: 834  KVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAK 893

Query: 624  SDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAV 683
             ++ +  K  P   ++       KE +  K+K       E+ ++    + A E + P A 
Sbjct: 894  KEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEK------TEVAKKEPDDAKAKEPSKP-AE 946

Query: 684  KDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSG 743
            K +A+PE +    EKAK      K K + K + D  T+     S   S+   +  E  S 
Sbjct: 947  KKEAAPEKKDTKEEKAKKPEE--KPKTEAKAKEDDKTL-----SKEPSKPKAEKAEKSSS 999

Query: 744  REGRKNKKEPKEPSPKQDVVGK 765
             + +K+ K P++ +  +   GK
Sbjct: 1000 TD-QKDSKPPEKATEDKAAKGK 1020


>gi|209977097 tripartite motif-containing 66 [Homo sapiens]
          Length = 1216

 Score = 70.5 bits (171), Expect = 9e-12
 Identities = 61/225 (27%), Positives = 96/225 (42%), Gaps = 32/225 (14%)

Query: 102  PQDGRNDFYCWVCHREGQVLCCELCPRVYHAKC--LRLTSEPEGDWFCPECEKITVAE-- 157
            P    N+ +C VC   G++LCC+ CP+V+H  C    L S P G+W C  C  +T  E  
Sbjct: 964  PAPIENEDFCAVCLNGGELLCCDRCPKVFHLSCHVPALLSFPGGEWVCTLCRSLTQPEME 1023

Query: 158  ------CIE----TQSKAMTMLTIEQLSYL-LKFAIQKMKQPGTDAFQKPV-PLEQHPDY 205
                  C        S  ++M   ++   L L      +  P    F +PV PL +H  Y
Sbjct: 1024 YDCENACYNQPGMRASPGLSMYDQKKCEKLVLSLCCNNLSLP----FHEPVSPLARH--Y 1077

Query: 206  AEYIFHPMDLCTLEKNAKKK---MYGCTEAFLADAKWILHNCIIYNGGNHKLTQIAKVVI 262
             + I  PMDL  + +  +KK    Y   E  ++D + +  NC  +N  + ++ +  + + 
Sbjct: 1078 YQIIKRPMDLSIIRRKLQKKDPAHYTTPEEVVSDVRLMFWNCAKFNYPDSEVAEAGRCLE 1137

Query: 263  KICEHEMNEIEVCPECYLAACQKRDNWFCE-----PCSNPHPLVW 302
               E  + EI   PE   A  ++ D+   E      CS P    W
Sbjct: 1138 VFFEGWLKEI--YPEKRFAQPRQEDSDSEEVSSESGCSTPQGFPW 1180


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 101/466 (21%), Positives = 166/466 (35%), Gaps = 41/466 (8%)

Query: 386 RTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRIS 445
           R+P  PN +       T     + +I ++  V  N + ++S     S    S  T R+I 
Sbjct: 94  RSPKPPNKK------KTKKVIESEEITEEHSVSENQESSSS-----SSSSSSSSTIRKIK 142

Query: 446 LSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASE--ESMDFLDKSTASPASTKTGQ 503
            S    +       +    + +   +KK T       E    +D  D    +P  T T Q
Sbjct: 143 SSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTP-DTSTTQ 201

Query: 504 AGSLSGSPK-----PFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQ 558
              +S SPK     P +P+ S P  + T K ++        ++  +     K+ S   ++
Sbjct: 202 HNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKE 261

Query: 559 QSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSS 618
           ++T         +  ++      K +     +         + T  E + +   E + ++
Sbjct: 262 KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTT 321

Query: 619 DSEYISDDEQKSKN---EPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVE-IKEELKSTSP 673
             E      + +     EP  T  K      KEP+    K+P PT P E      K  +P
Sbjct: 322 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 381

Query: 674 ASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESEL 733
            + K+ P   K+ A   P+K       P+P   K+      +  +PT        ++   
Sbjct: 382 TTTKSAPTTPKEPAPTTPKK-------PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA 434

Query: 734 VIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSP--PETPV-LTRSSAQT 790
                E       +     PKEP+P      K P  TT    SP  P+ P   T  SA T
Sbjct: 435 PTTPKEPAPTAPKKPAPTTPKEPAP---TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 491

Query: 791 SAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQR 836
           +      TT+ S+  T   P+P  T  P     P  PKE AP   +
Sbjct: 492 TTKEPAPTTTKSAPTTPKEPSPTTTKEPA----PTTPKEPAPTTPK 533



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 85/400 (21%), Positives = 134/400 (33%), Gaps = 73/400 (18%)

Query: 491 KSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLK 550
           K T  P       +G  +G  K  +P  S   TT+ +K ST+  I               
Sbjct: 170 KPTPKPPVVDEAGSGLDNGDFKVTTPDTS---TTQHNKVSTSPKI--------------- 211

Query: 551 ELSESVQQQSTPVPLISPKRQIRSRFQLNLDK--TIESCKAQLGINEISED-VYTAVEHS 607
               +  +   P P + P         L ++K  T+E+ +      + S D         
Sbjct: 212 ----TTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAK 267

Query: 608 DSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVEIKE 666
           +++  EK+ + D    S    K   + E T         KEP+    K+P  T P E   
Sbjct: 268 ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP 327

Query: 667 ELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLD 726
               ++P + K +P     K++P   K+      P+P   K+      +  +PT      
Sbjct: 328 TTIKSAPTTPK-EPAPTTTKSAPTTPKE------PAPTTTKEPAPTTPKEPAPTT----- 375

Query: 727 SDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRS 786
                                      KEP+P       T P     +      P   + 
Sbjct: 376 --------------------------TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 409

Query: 787 SAQTSAAGATATTSTSSTVTVTAPAPAATGSPV----KKQRPLLPKETAPAVQRVVWNSS 842
            A T+    T TT      T   PAP     P     KK  P  PKE AP   +    ++
Sbjct: 410 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 469

Query: 843 TVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSS 882
           T +      SP+T      T+T+S+P  T   + +T  S+
Sbjct: 470 TKE-----PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 504



 Score = 53.9 bits (128), Expect = 9e-07
 Identities = 66/283 (23%), Positives = 102/283 (36%), Gaps = 38/283 (13%)

Query: 633 EPEDTEDKEGCQMDKEPSA--VKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPE 690
           EP  T  KE      + +A    K+P PT P   K   K  +P + K       DK +P 
Sbjct: 723 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK--KPAPKELAPTTTKGPTSTTSDKPAPT 780

Query: 691 PEKDFSEKAKPSPHPIKDKLKGKDETDSP---TVHLGLDSDSESELVIDLGEDHSGRE-G 746
             K+ +      P P   K       ++P   T  +   + ++    I    D S  E  
Sbjct: 781 TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS 840

Query: 747 RKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 806
            +   +  E SPK+  V  T            +TP  T+    T+A   T      +T  
Sbjct: 841 AEPTPKALENSPKEPGVPTT------------KTPAATKPEMTTTAKDKTTERDLRTTPE 888

Query: 807 VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTST----ITLVT 862
            T  AP  T            KETA   ++   +  T    ++T + +  T    IT + 
Sbjct: 889 TTTAAPKMT------------KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLK 936

Query: 863 STQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTS 905
           +T  +P VT++    T    +N   P  TA     A  +K T+
Sbjct: 937 TTTLAPKVTTTKKTITTTEIMNK--PEETAKPKDRATNSKATT 977



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 97/434 (22%), Positives = 151/434 (34%), Gaps = 53/434 (12%)

Query: 492 STASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE 551
           +T  PA T T  A +    P P + +  AP T K +   TT         +  A    KE
Sbjct: 492 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKE 550

Query: 552 LSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSED 611
            + +  ++  P    +PK    +  +    +T  +   +L      +   T  E      
Sbjct: 551 PAPTTTKKPAPT---TPKEPAPTTPK----ETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 603

Query: 612 SEKSDSSDSEYISDDEQKSKNEPEDTEDKEGC-QMDKEPS-AVKKKPKPTNPVEIKEEL- 668
            E+   +  E   +    +  EP  T  K       KEP+    K+P PT P E      
Sbjct: 604 PEELAPTTPE---EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 660

Query: 669 KSTSPASEKAD-PGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDS 727
           K T+P + K   P  +K+ A   P+K   ++  P+    K+      +  +PT   G   
Sbjct: 661 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT--TKEPTSTTCDKPAPTTPKGTAP 718

Query: 728 DSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSS 787
            +                       PKEP+P      K P  TT    +P        ++
Sbjct: 719 TT-----------------------PKEPAP---TTPKEPAPTTPKGTAPTTLKEPAPTT 752

Query: 788 AQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQK 847
            +  A    A T+T    + T+  PA T    K+  P  PKE AP   +           
Sbjct: 753 PKKPAPKELAPTTTKGPTSTTSDKPAPT--TPKETAPTTPKEPAPTTPK-----KPAPTT 805

Query: 848 EITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKM 907
             T  P+TS ++  T+T+    +  S   ST   S     P   A  +   +    T+K 
Sbjct: 806 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE---PTPKALENSPKEPGVPTTKT 862

Query: 908 MDAIKGTMTEIYND 921
             A K  MT    D
Sbjct: 863 PAATKPEMTTTAKD 876



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 73/391 (18%), Positives = 142/391 (36%), Gaps = 80/391 (20%)

Query: 471 EKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTS 530
           ++ ++SS  S+S  ++  +  S  S A+ +  +   +  + K  + +   P     D+  
Sbjct: 123 QESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAG 182

Query: 531 TTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQ 590
           +        LD    ++   + S +   + +  P I+  + I  R  L  +         
Sbjct: 183 S-------GLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPN--------- 226

Query: 591 LGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEP- 649
              ++ S++    V    + +++++ +++ +  +D ++K+ +  E    ++    D  P 
Sbjct: 227 ---SDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPT 283

Query: 650 SAVKKKPKPTNPVEIKEELKSTSPA---SEKADPGAVKDKASPEPEKDFSEKAKPSPHPI 706
           S V  KP P      K E  +  PA    ++  P   K+ AS  P++       P+P  I
Sbjct: 284 SKVLAKPTP------KAETTTKGPALTTPKEPTPTTPKEPASTTPKE-------PTPTTI 330

Query: 707 KDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKT 766
           K          +PT                                PKEP+P       T
Sbjct: 331 KS---------APTT-------------------------------PKEPAPTTTKSAPT 350

Query: 767 PPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLL 826
            P     + +    P   +  A T+      TT+ S+  T   PAP       KK  P  
Sbjct: 351 TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP----KKPAPTT 406

Query: 827 PKETAPAVQRVVWNSSTVQQKEITQSPSTST 857
           PKE AP   +    ++  +    T+ P+ +T
Sbjct: 407 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT 437



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 106/547 (19%), Positives = 172/547 (31%), Gaps = 77/547 (14%)

Query: 387 TPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRISL 446
           T  T  +  Q   D    +    +    EK     D+  + K+L +KP     T  +   
Sbjct: 245 TKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK-DLAPTSKVL-AKPTPKAETTTKGPA 302

Query: 447 SDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS 506
              P+ P  T       +  ++       S+  +  E +      +T S  +T    A +
Sbjct: 303 LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA----PTTTKSAPTTPKEPAPT 358

Query: 507 LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLD------RSKAEMDLKELSESVQQQS 560
            +  P P +P+  AP TTK    +TT S      +      +  A    KE + +  ++ 
Sbjct: 359 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 418

Query: 561 TPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEH----SDSEDSEKSD 616
           TP     P    +        +   +   +       E   T  +     +  E S  + 
Sbjct: 419 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 478

Query: 617 SSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVE------------ 663
              +   +     +  EP  T  K      KEPS    K+P PT P E            
Sbjct: 479 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 538

Query: 664 IKEELKSTSP------ASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKD-ET 716
             +E   T+P       ++K  P   K+ A   P++      K       +KL     E 
Sbjct: 539 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 598

Query: 717 DSPTVHLGLDSDSESELVIDLGEDHSGREGR----KNKKEPKEPSPKQDVVG-------- 764
            +PT    L   +  E      E+ +    +       KEP   +PK+            
Sbjct: 599 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 658

Query: 765 ------------------KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 806
                             K P  TT    +P E    T     ++     A T+   T  
Sbjct: 659 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 718

Query: 807 VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQS 866
            T   PA T    K+  P  PK TAP         +T+++   T     +   L  +T  
Sbjct: 719 TTPKEPAPT--TPKEPAPTTPKGTAP---------TTLKEPAPTTPKKPAPKELAPTTTK 767

Query: 867 SPLVTSS 873
            P  T+S
Sbjct: 768 GPTSTTS 774



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 60/265 (22%), Positives = 101/265 (38%), Gaps = 36/265 (13%)

Query: 649 PSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKD 708
           P + KK P P+      + +KST+  S K  P   K K   E E + +E+   S +  ++
Sbjct: 72  PPSSKKAPPPSGA---SQTIKSTTKRSPKP-PNKKKTKKVIESE-EITEEHSVSEN--QE 124

Query: 709 KLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPP 768
                  + S +    + S   S    +L +    ++ +KN+ + K+P+PK  VV +   
Sbjct: 125 SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTK-KKPTPKPPVVDEAGS 183

Query: 769 STTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPK 828
               G                      T  TST+    V+      T  P+   RP LP 
Sbjct: 184 GLDNGDFKV-----------------TTPDTSTTQHNKVSTSPKITTAKPINP-RPSLPP 225

Query: 829 ETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLP 888
            +  + +     S TV ++   ++  T+T    TST      TS+    ++  +   DL 
Sbjct: 226 NSDTSKE----TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL- 280

Query: 889 IATASADVAADIAKYTSKMMDAIKG 913
                A  +  +AK T K     KG
Sbjct: 281 -----APTSKVLAKPTPKAETTTKG 300



 Score = 38.1 bits (87), Expect = 0.049
 Identities = 55/254 (21%), Positives = 91/254 (35%), Gaps = 36/254 (14%)

Query: 450  PRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSG 509
            P +P  T S V T +       K+ T+ H S  E + +     +A P       +    G
Sbjct: 806  PETPPPTTSEVSTPTTT-----KEPTTIHKSPDESTPEL----SAEPTPKALENSPKEPG 856

Query: 510  SPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPK 569
             P   +P  + P  T T K  TT   L    + + A   + + + +  +++T   + +  
Sbjct: 857  VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 916

Query: 570  RQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQK 629
             Q+ S        T       L    ++  V T           K   + +E +      
Sbjct: 917  TQVTS---TTTQDTTPFKITTLKTTTLAPKVTTT----------KKTITTTEIM------ 957

Query: 630  SKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASP 689
              N+PE+T   +    D+  ++    PKP  P   K   K TS    K  P   K K +P
Sbjct: 958  --NKPEETAKPK----DRATNSKATTPKPQKPT--KAPKKPTSTKKPKTMPRVRKPKTTP 1009

Query: 690  EPEKDFSEKAKPSP 703
             P K  S   + +P
Sbjct: 1010 TPRKMTSTMPELNP 1023


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 101/466 (21%), Positives = 166/466 (35%), Gaps = 41/466 (8%)

Query: 386 RTPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRIS 445
           R+P  PN +       T     + +I ++  V  N + ++S     S    S  T R+I 
Sbjct: 135 RSPKPPNKK------KTKKVIESEEITEEHSVSENQESSSS-----SSSSSSSSTIRKIK 183

Query: 446 LSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASE--ESMDFLDKSTASPASTKTGQ 503
            S    +       +    + +   +KK T       E    +D  D    +P  T T Q
Sbjct: 184 SSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTP-DTSTTQ 242

Query: 504 AGSLSGSPK-----PFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQ 558
              +S SPK     P +P+ S P  + T K ++        ++  +     K+ S   ++
Sbjct: 243 HNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKE 302

Query: 559 QSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSS 618
           ++T         +  ++      K +     +         + T  E + +   E + ++
Sbjct: 303 KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTT 362

Query: 619 DSEYISDDEQKSKN---EPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVE-IKEELKSTSP 673
             E      + +     EP  T  K      KEP+    K+P PT P E      K  +P
Sbjct: 363 PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 422

Query: 674 ASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESEL 733
            + K+ P   K+ A   P+K       P+P   K+      +  +PT        ++   
Sbjct: 423 TTTKSAPTTPKEPAPTTPKK-------PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA 475

Query: 734 VIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSP--PETPV-LTRSSAQT 790
                E       +     PKEP+P      K P  TT    SP  P+ P   T  SA T
Sbjct: 476 PTTPKEPAPTAPKKPAPTTPKEPAP---TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPT 532

Query: 791 SAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQR 836
           +      TT+ S+  T   P+P  T  P     P  PKE AP   +
Sbjct: 533 TTKEPAPTTTKSAPTTPKEPSPTTTKEPA----PTTPKEPAPTTPK 574



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 85/400 (21%), Positives = 134/400 (33%), Gaps = 73/400 (18%)

Query: 491 KSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLK 550
           K T  P       +G  +G  K  +P  S   TT+ +K ST+  I               
Sbjct: 211 KPTPKPPVVDEAGSGLDNGDFKVTTPDTS---TTQHNKVSTSPKI--------------- 252

Query: 551 ELSESVQQQSTPVPLISPKRQIRSRFQLNLDK--TIESCKAQLGINEISED-VYTAVEHS 607
               +  +   P P + P         L ++K  T+E+ +      + S D         
Sbjct: 253 ----TTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAK 308

Query: 608 DSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVEIKE 666
           +++  EK+ + D    S    K   + E T         KEP+    K+P  T P E   
Sbjct: 309 ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP 368

Query: 667 ELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLD 726
               ++P + K +P     K++P   K+      P+P   K+      +  +PT      
Sbjct: 369 TTIKSAPTTPK-EPAPTTTKSAPTTPKE------PAPTTTKEPAPTTPKEPAPTT----- 416

Query: 727 SDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRS 786
                                      KEP+P       T P     +      P   + 
Sbjct: 417 --------------------------TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 450

Query: 787 SAQTSAAGATATTSTSSTVTVTAPAPAATGSPV----KKQRPLLPKETAPAVQRVVWNSS 842
            A T+    T TT      T   PAP     P     KK  P  PKE AP   +    ++
Sbjct: 451 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 510

Query: 843 TVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSS 882
           T +      SP+T      T+T+S+P  T   + +T  S+
Sbjct: 511 TKE-----PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 545



 Score = 53.9 bits (128), Expect = 9e-07
 Identities = 66/283 (23%), Positives = 102/283 (36%), Gaps = 38/283 (13%)

Query: 633  EPEDTEDKEGCQMDKEPSA--VKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPE 690
            EP  T  KE      + +A    K+P PT P   K   K  +P + K       DK +P 
Sbjct: 764  EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK--KPAPKELAPTTTKGPTSTTSDKPAPT 821

Query: 691  PEKDFSEKAKPSPHPIKDKLKGKDETDSP---TVHLGLDSDSESELVIDLGEDHSGRE-G 746
              K+ +      P P   K       ++P   T  +   + ++    I    D S  E  
Sbjct: 822  TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS 881

Query: 747  RKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 806
             +   +  E SPK+  V  T            +TP  T+    T+A   T      +T  
Sbjct: 882  AEPTPKALENSPKEPGVPTT------------KTPAATKPEMTTTAKDKTTERDLRTTPE 929

Query: 807  VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTST----ITLVT 862
             T  AP  T            KETA   ++   +  T    ++T + +  T    IT + 
Sbjct: 930  TTTAAPKMT------------KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLK 977

Query: 863  STQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTS 905
            +T  +P VT++    T    +N   P  TA     A  +K T+
Sbjct: 978  TTTLAPKVTTTKKTITTTEIMNK--PEETAKPKDRATNSKATT 1018



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 97/434 (22%), Positives = 151/434 (34%), Gaps = 53/434 (12%)

Query: 492 STASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE 551
           +T  PA T T  A +    P P + +  AP T K +   TT         +  A    KE
Sbjct: 533 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKE 591

Query: 552 LSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSED 611
            + +  ++  P    +PK    +  +    +T  +   +L      +   T  E      
Sbjct: 592 PAPTTTKKPAPT---TPKEPAPTTPK----ETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 644

Query: 612 SEKSDSSDSEYISDDEQKSKNEPEDTEDKEGC-QMDKEPS-AVKKKPKPTNPVEIKEEL- 668
            E+   +  E   +    +  EP  T  K       KEP+    K+P PT P E      
Sbjct: 645 PEELAPTTPE---EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 701

Query: 669 KSTSPASEKAD-PGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDS 727
           K T+P + K   P  +K+ A   P+K   ++  P+    K+      +  +PT   G   
Sbjct: 702 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT--TKEPTSTTCDKPAPTTPKGTAP 759

Query: 728 DSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSS 787
            +                       PKEP+P      K P  TT    +P        ++
Sbjct: 760 TT-----------------------PKEPAP---TTPKEPAPTTPKGTAPTTLKEPAPTT 793

Query: 788 AQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQK 847
            +  A    A T+T    + T+  PA T    K+  P  PKE AP   +           
Sbjct: 794 PKKPAPKELAPTTTKGPTSTTSDKPAPT--TPKETAPTTPKEPAPTTPK-----KPAPTT 846

Query: 848 EITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKM 907
             T  P+TS ++  T+T+    +  S   ST   S     P   A  +   +    T+K 
Sbjct: 847 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE---PTPKALENSPKEPGVPTTKT 903

Query: 908 MDAIKGTMTEIYND 921
             A K  MT    D
Sbjct: 904 PAATKPEMTTTAKD 917



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 73/391 (18%), Positives = 142/391 (36%), Gaps = 80/391 (20%)

Query: 471 EKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTS 530
           ++ ++SS  S+S  ++  +  S  S A+ +  +   +  + K  + +   P     D+  
Sbjct: 164 QESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAG 223

Query: 531 TTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQ 590
           +        LD    ++   + S +   + +  P I+  + I  R  L  +         
Sbjct: 224 S-------GLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPN--------- 267

Query: 591 LGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEP- 649
              ++ S++    V    + +++++ +++ +  +D ++K+ +  E    ++    D  P 
Sbjct: 268 ---SDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPT 324

Query: 650 SAVKKKPKPTNPVEIKEELKSTSPA---SEKADPGAVKDKASPEPEKDFSEKAKPSPHPI 706
           S V  KP P      K E  +  PA    ++  P   K+ AS  P++       P+P  I
Sbjct: 325 SKVLAKPTP------KAETTTKGPALTTPKEPTPTTPKEPASTTPKE-------PTPTTI 371

Query: 707 KDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKT 766
           K          +PT                                PKEP+P       T
Sbjct: 372 KS---------APTT-------------------------------PKEPAPTTTKSAPT 391

Query: 767 PPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLL 826
            P     + +    P   +  A T+      TT+ S+  T   PAP       KK  P  
Sbjct: 392 TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP----KKPAPTT 447

Query: 827 PKETAPAVQRVVWNSSTVQQKEITQSPSTST 857
           PKE AP   +    ++  +    T+ P+ +T
Sbjct: 448 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT 478



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 106/547 (19%), Positives = 172/547 (31%), Gaps = 77/547 (14%)

Query: 387 TPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRISL 446
           T  T  +  Q   D    +    +    EK     D+  + K+L +KP     T  +   
Sbjct: 286 TKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK-DLAPTSKVL-AKPTPKAETTTKGPA 343

Query: 447 SDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS 506
              P+ P  T       +  ++       S+  +  E +      +T S  +T    A +
Sbjct: 344 LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA----PTTTKSAPTTPKEPAPT 399

Query: 507 LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLD------RSKAEMDLKELSESVQQQS 560
            +  P P +P+  AP TTK    +TT S      +      +  A    KE + +  ++ 
Sbjct: 400 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 459

Query: 561 TPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEH----SDSEDSEKSD 616
           TP     P    +        +   +   +       E   T  +     +  E S  + 
Sbjct: 460 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 519

Query: 617 SSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVE------------ 663
              +   +     +  EP  T  K      KEPS    K+P PT P E            
Sbjct: 520 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 579

Query: 664 IKEELKSTSP------ASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKD-ET 716
             +E   T+P       ++K  P   K+ A   P++      K       +KL     E 
Sbjct: 580 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 639

Query: 717 DSPTVHLGLDSDSESELVIDLGEDHSGREGR----KNKKEPKEPSPKQDVVG-------- 764
            +PT    L   +  E      E+ +    +       KEP   +PK+            
Sbjct: 640 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 699

Query: 765 ------------------KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 806
                             K P  TT    +P E    T     ++     A T+   T  
Sbjct: 700 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 759

Query: 807 VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQS 866
            T   PA T    K+  P  PK TAP         +T+++   T     +   L  +T  
Sbjct: 760 TTPKEPAPT--TPKEPAPTTPKGTAP---------TTLKEPAPTTPKKPAPKELAPTTTK 808

Query: 867 SPLVTSS 873
            P  T+S
Sbjct: 809 GPTSTTS 815



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 60/265 (22%), Positives = 101/265 (38%), Gaps = 36/265 (13%)

Query: 649 PSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKD 708
           P + KK P P+      + +KST+  S K  P   K K   E E + +E+   S +  ++
Sbjct: 113 PPSSKKAPPPSGA---SQTIKSTTKRSPKP-PNKKKTKKVIESE-EITEEHSVSEN--QE 165

Query: 709 KLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPP 768
                  + S +    + S   S    +L +    ++ +KN+ + K+P+PK  VV +   
Sbjct: 166 SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTK-KKPTPKPPVVDEAGS 224

Query: 769 STTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPK 828
               G                      T  TST+    V+      T  P+   RP LP 
Sbjct: 225 GLDNGDFKV-----------------TTPDTSTTQHNKVSTSPKITTAKPINP-RPSLPP 266

Query: 829 ETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLP 888
            +  + +     S TV ++   ++  T+T    TST      TS+    ++  +   DL 
Sbjct: 267 NSDTSKE----TSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL- 321

Query: 889 IATASADVAADIAKYTSKMMDAIKG 913
                A  +  +AK T K     KG
Sbjct: 322 -----APTSKVLAKPTPKAETTTKG 341



 Score = 38.1 bits (87), Expect = 0.049
 Identities = 55/254 (21%), Positives = 91/254 (35%), Gaps = 36/254 (14%)

Query: 450  PRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSG 509
            P +P  T S V T +       K+ T+ H S  E + +     +A P       +    G
Sbjct: 847  PETPPPTTSEVSTPTTT-----KEPTTIHKSPDESTPEL----SAEPTPKALENSPKEPG 897

Query: 510  SPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPK 569
             P   +P  + P  T T K  TT   L    + + A   + + + +  +++T   + +  
Sbjct: 898  VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 957

Query: 570  RQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQK 629
             Q+ S        T       L    ++  V T           K   + +E +      
Sbjct: 958  TQVTS---TTTQDTTPFKITTLKTTTLAPKVTTT----------KKTITTTEIM------ 998

Query: 630  SKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASP 689
              N+PE+T   +    D+  ++    PKP  P   K   K TS    K  P   K K +P
Sbjct: 999  --NKPEETAKPK----DRATNSKATTPKPQKPT--KAPKKPTSTKKPKTMPRVRKPKTTP 1050

Query: 690  EPEKDFSEKAKPSP 703
             P K  S   + +P
Sbjct: 1051 TPRKMTSTMPELNP 1064


>gi|20357588 TBP-associated factor 1 isoform 2 [Homo sapiens]
          Length = 1872

 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 37/101 (36%), Positives = 56/101 (55%), Gaps = 1/101 (0%)

Query: 174  LSYLLKFAIQKMKQ-PGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEA 232
            LS +L+  I  M+  P T  F  PV  +   DY + I  PMDL TL +N +K++Y   E 
Sbjct: 1385 LSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREE 1444

Query: 233  FLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIE 273
            F    + I+ N   YNG  H LTQI++ ++ +C+ ++ E E
Sbjct: 1445 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKE 1485



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 32/89 (35%), Positives = 47/89 (52%)

Query: 185  MKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNC 244
            M  P +  F  PV  +  PDY + I +PMDL T+ KN  K  Y   E+FL D   IL N 
Sbjct: 1520 MAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANS 1579

Query: 245  IIYNGGNHKLTQIAKVVIKICEHEMNEIE 273
            + YNG   + T+ A+ ++ +C   + E +
Sbjct: 1580 VKYNGPESQYTKTAQEIVNVCYQTLTEYD 1608


>gi|20357585 TBP-associated factor 1 isoform 1 [Homo sapiens]
          Length = 1893

 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 37/101 (36%), Positives = 56/101 (55%), Gaps = 1/101 (0%)

Query: 174  LSYLLKFAIQKMKQ-PGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEA 232
            LS +L+  I  M+  P T  F  PV  +   DY + I  PMDL TL +N +K++Y   E 
Sbjct: 1406 LSSILESIINDMRDLPNTYPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKRLYPSREE 1465

Query: 233  FLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIE 273
            F    + I+ N   YNG  H LTQI++ ++ +C+ ++ E E
Sbjct: 1466 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKE 1506



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 32/89 (35%), Positives = 47/89 (52%)

Query: 185  MKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNC 244
            M  P +  F  PV  +  PDY + I +PMDL T+ KN  K  Y   E+FL D   IL N 
Sbjct: 1541 MAVPDSWPFHHPVNKKFVPDYYKVIVNPMDLETIRKNISKHKYQSRESFLDDVNLILANS 1600

Query: 245  IIYNGGNHKLTQIAKVVIKICEHEMNEIE 273
            + YNG   + T+ A+ ++ +C   + E +
Sbjct: 1601 VKYNGPESQYTKTAQEIVNVCYQTLTEYD 1629


>gi|24429572 TBP-associated factor RNA polymerase 1-like [Homo
            sapiens]
          Length = 1826

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 37/101 (36%), Positives = 55/101 (54%), Gaps = 1/101 (0%)

Query: 174  LSYLLKFAIQKMKQ-PGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEA 232
            LS +L+  I  M+  P T  F  PV  +   DY + I  PMDL TL +N +K +Y   E 
Sbjct: 1404 LSSILESIINDMRDLPNTHPFHTPVNAKVVKDYYKIITRPMDLQTLRENVRKCLYPSREE 1463

Query: 233  FLADAKWILHNCIIYNGGNHKLTQIAKVVIKICEHEMNEIE 273
            F    + I+ N   YNG  H LTQI++ ++ +C+ ++ E E
Sbjct: 1464 FREHLELIVKNSATYNGPKHSLTQISQSMLDLCDEKLKEKE 1504



 Score = 60.8 bits (146), Expect = 7e-09
 Identities = 32/89 (35%), Positives = 47/89 (52%)

Query: 185  MKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAKWILHNC 244
            M  P +  F  PV  +  PDY + I +P+DL T+ KN  K  Y   E+FL D   IL N 
Sbjct: 1539 MAVPDSWPFHHPVNKKFVPDYYKMIVNPVDLETIRKNISKHKYQSRESFLDDVNLILANS 1598

Query: 245  IIYNGGNHKLTQIAKVVIKICEHEMNEIE 273
            + YNG   + T+ A+ ++ IC   + E +
Sbjct: 1599 VKYNGPESQYTKTAQEIVNICYQTITEYD 1627


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 85/387 (21%), Positives = 140/387 (36%), Gaps = 29/387 (7%)

Query: 465 DVEQDAEKKATSSHFSASEESMDFLDKST--ASPASTKTGQAGSLSGSPK-----PFSPQ 517
           D +++  KK  +      +E+   LD      +   T T Q   +S SPK     P +P+
Sbjct: 68  DNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR 127

Query: 518 LSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQ 577
            S P  + T K ++        ++  +     K+ S   ++++T         +  ++  
Sbjct: 128 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 187

Query: 578 LNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQKSKN---EP 634
               K +     +         + T  E + +   E + ++  E      + +     EP
Sbjct: 188 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 247

Query: 635 EDTEDKEGCQMDKEPS-AVKKKPKPTNPVE-IKEELKSTSPASEKADPGAVKDKASPEPE 692
             T  K      KEP+    K+P PT P E      K  +P + K+ P   K+ A   P+
Sbjct: 248 APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 307

Query: 693 KDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKE 752
           K       P+P   K+      +  +PT        ++        E       +     
Sbjct: 308 K-------PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT 360

Query: 753 PKEPSPKQDVVGKTPPSTTVGSHSP--PETPV-LTRSSAQTSAAGATATTSTSSTVTVTA 809
           PKEP+P      K P  TT    SP  P+ P   T  SA T+      TT+ S+  T   
Sbjct: 361 PKEPAP---TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 417

Query: 810 PAPAATGSPVKKQRPLLPKETAPAVQR 836
           P+P  T  P     P  PKE AP   +
Sbjct: 418 PSPTTTKEPA----PTTPKEPAPTTPK 440



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 85/400 (21%), Positives = 134/400 (33%), Gaps = 73/400 (18%)

Query: 491 KSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLK 550
           K T  P       +G  +G  K  +P  S   TT+ +K ST+  I               
Sbjct: 77  KPTPKPPVVDEAGSGLDNGDFKVTTPDTS---TTQHNKVSTSPKI--------------- 118

Query: 551 ELSESVQQQSTPVPLISPKRQIRSRFQLNLDK--TIESCKAQLGINEISED-VYTAVEHS 607
               +  +   P P + P         L ++K  T+E+ +      + S D         
Sbjct: 119 ----TTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAK 174

Query: 608 DSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVEIKE 666
           +++  EK+ + D    S    K   + E T         KEP+    K+P  T P E   
Sbjct: 175 ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP 234

Query: 667 ELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLD 726
               ++P + K +P     K++P   K+      P+P   K+      +  +PT      
Sbjct: 235 TTIKSAPTTPK-EPAPTTTKSAPTTPKE------PAPTTTKEPAPTTPKEPAPTT----- 282

Query: 727 SDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRS 786
                                      KEP+P       T P     +      P   + 
Sbjct: 283 --------------------------TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 316

Query: 787 SAQTSAAGATATTSTSSTVTVTAPAPAATGSPV----KKQRPLLPKETAPAVQRVVWNSS 842
            A T+    T TT      T   PAP     P     KK  P  PKE AP   +    ++
Sbjct: 317 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 376

Query: 843 TVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSS 882
           T +      SP+T      T+T+S+P  T   + +T  S+
Sbjct: 377 TKE-----PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 411



 Score = 53.9 bits (128), Expect = 9e-07
 Identities = 66/283 (23%), Positives = 102/283 (36%), Gaps = 38/283 (13%)

Query: 633 EPEDTEDKEGCQMDKEPSA--VKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPE 690
           EP  T  KE      + +A    K+P PT P   K   K  +P + K       DK +P 
Sbjct: 630 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK--KPAPKELAPTTTKGPTSTTSDKPAPT 687

Query: 691 PEKDFSEKAKPSPHPIKDKLKGKDETDSP---TVHLGLDSDSESELVIDLGEDHSGRE-G 746
             K+ +      P P   K       ++P   T  +   + ++    I    D S  E  
Sbjct: 688 TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS 747

Query: 747 RKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 806
            +   +  E SPK+  V  T            +TP  T+    T+A   T      +T  
Sbjct: 748 AEPTPKALENSPKEPGVPTT------------KTPAATKPEMTTTAKDKTTERDLRTTPE 795

Query: 807 VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTST----ITLVT 862
            T  AP  T            KETA   ++   +  T    ++T + +  T    IT + 
Sbjct: 796 TTTAAPKMT------------KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLK 843

Query: 863 STQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTS 905
           +T  +P VT++    T    +N   P  TA     A  +K T+
Sbjct: 844 TTTLAPKVTTTKKTITTTEIMNK--PEETAKPKDRATNSKATT 884



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 97/434 (22%), Positives = 151/434 (34%), Gaps = 53/434 (12%)

Query: 492 STASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE 551
           +T  PA T T  A +    P P + +  AP T K +   TT         +  A    KE
Sbjct: 399 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKE 457

Query: 552 LSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSED 611
            + +  ++  P    +PK    +  +    +T  +   +L      +   T  E      
Sbjct: 458 PAPTTTKKPAPT---TPKEPAPTTPK----ETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 510

Query: 612 SEKSDSSDSEYISDDEQKSKNEPEDTEDKEGC-QMDKEPS-AVKKKPKPTNPVEIKEEL- 668
            E+   +  E   +    +  EP  T  K       KEP+    K+P PT P E      
Sbjct: 511 PEELAPTTPE---EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 567

Query: 669 KSTSPASEKAD-PGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDS 727
           K T+P + K   P  +K+ A   P+K   ++  P+    K+      +  +PT   G   
Sbjct: 568 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT--TKEPTSTTCDKPAPTTPKGTAP 625

Query: 728 DSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSS 787
            +                       PKEP+P      K P  TT    +P        ++
Sbjct: 626 TT-----------------------PKEPAP---TTPKEPAPTTPKGTAPTTLKEPAPTT 659

Query: 788 AQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQK 847
            +  A    A T+T    + T+  PA T    K+  P  PKE AP   +           
Sbjct: 660 PKKPAPKELAPTTTKGPTSTTSDKPAPT--TPKETAPTTPKEPAPTTPK-----KPAPTT 712

Query: 848 EITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKM 907
             T  P+TS ++  T+T+    +  S   ST   S     P   A  +   +    T+K 
Sbjct: 713 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE---PTPKALENSPKEPGVPTTKT 769

Query: 908 MDAIKGTMTEIYND 921
             A K  MT    D
Sbjct: 770 PAATKPEMTTTAKD 783



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 106/547 (19%), Positives = 172/547 (31%), Gaps = 77/547 (14%)

Query: 387 TPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRISL 446
           T  T  +  Q   D    +    +    EK     D+  + K+L +KP     T  +   
Sbjct: 152 TKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK-DLAPTSKVL-AKPTPKAETTTKGPA 209

Query: 447 SDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS 506
              P+ P  T       +  ++       S+  +  E +      +T S  +T    A +
Sbjct: 210 LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA----PTTTKSAPTTPKEPAPT 265

Query: 507 LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLD------RSKAEMDLKELSESVQQQS 560
            +  P P +P+  AP TTK    +TT S      +      +  A    KE + +  ++ 
Sbjct: 266 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 325

Query: 561 TPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEH----SDSEDSEKSD 616
           TP     P    +        +   +   +       E   T  +     +  E S  + 
Sbjct: 326 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 385

Query: 617 SSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVE------------ 663
              +   +     +  EP  T  K      KEPS    K+P PT P E            
Sbjct: 386 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 445

Query: 664 IKEELKSTSP------ASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKD-ET 716
             +E   T+P       ++K  P   K+ A   P++      K       +KL     E 
Sbjct: 446 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 505

Query: 717 DSPTVHLGLDSDSESELVIDLGEDHSGREGR----KNKKEPKEPSPKQDVVG-------- 764
            +PT    L   +  E      E+ +    +       KEP   +PK+            
Sbjct: 506 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 565

Query: 765 ------------------KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 806
                             K P  TT    +P E    T     ++     A T+   T  
Sbjct: 566 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 625

Query: 807 VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQS 866
            T   PA T    K+  P  PK TAP         +T+++   T     +   L  +T  
Sbjct: 626 TTPKEPAPT--TPKEPAPTTPKGTAP---------TTLKEPAPTTPKKPAPKELAPTTTK 674

Query: 867 SPLVTSS 873
            P  T+S
Sbjct: 675 GPTSTTS 681



 Score = 38.1 bits (87), Expect = 0.049
 Identities = 55/254 (21%), Positives = 91/254 (35%), Gaps = 36/254 (14%)

Query: 450 PRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSG 509
           P +P  T S V T +       K+ T+ H S  E + +     +A P       +    G
Sbjct: 713 PETPPPTTSEVSTPTTT-----KEPTTIHKSPDESTPEL----SAEPTPKALENSPKEPG 763

Query: 510 SPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPK 569
            P   +P  + P  T T K  TT   L    + + A   + + + +  +++T   + +  
Sbjct: 764 VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 823

Query: 570 RQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQK 629
            Q+ S        T       L    ++  V T           K   + +E +      
Sbjct: 824 TQVTS---TTTQDTTPFKITTLKTTTLAPKVTTT----------KKTITTTEIM------ 864

Query: 630 SKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASP 689
             N+PE+T   +    D+  ++    PKP  P   K   K TS    K  P   K K +P
Sbjct: 865 --NKPEETAKPK----DRATNSKATTPKPQKPT--KAPKKPTSTKKPKTMPRVRKPKTTP 916

Query: 690 EPEKDFSEKAKPSP 703
            P K  S   + +P
Sbjct: 917 TPRKMTSTMPELNP 930



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 39/170 (22%), Positives = 64/170 (37%), Gaps = 29/170 (17%)

Query: 744 REGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSS 803
           ++ +KN+ + K+P+PK  VV +       G                      T  TST+ 
Sbjct: 67  KDNKKNRTK-KKPTPKPPVVDEAGSGLDNGDFKV-----------------TTPDTSTTQ 108

Query: 804 TVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTS 863
              V+      T  P+   RP LP  +  + +     S TV ++   ++  T+T    TS
Sbjct: 109 HNKVSTSPKITTAKPINP-RPSLPPNSDTSKE----TSLTVNKETTVETKETTTTNKQTS 163

Query: 864 TQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKG 913
           T      TS+    ++  +   DL      A  +  +AK T K     KG
Sbjct: 164 TDGKEKTTSAKETQSIEKTSAKDL------APTSKVLAKPTPKAETTTKG 207


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 85/387 (21%), Positives = 140/387 (36%), Gaps = 29/387 (7%)

Query: 465 DVEQDAEKKATSSHFSASEESMDFLDKST--ASPASTKTGQAGSLSGSPK-----PFSPQ 517
           D +++  KK  +      +E+   LD      +   T T Q   +S SPK     P +P+
Sbjct: 109 DNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR 168

Query: 518 LSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPKRQIRSRFQ 577
            S P  + T K ++        ++  +     K+ S   ++++T         +  ++  
Sbjct: 169 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 228

Query: 578 LNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQKSKN---EP 634
               K +     +         + T  E + +   E + ++  E      + +     EP
Sbjct: 229 APTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEP 288

Query: 635 EDTEDKEGCQMDKEPS-AVKKKPKPTNPVE-IKEELKSTSPASEKADPGAVKDKASPEPE 692
             T  K      KEP+    K+P PT P E      K  +P + K+ P   K+ A   P+
Sbjct: 289 APTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK 348

Query: 693 KDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHSGREGRKNKKE 752
           K       P+P   K+      +  +PT        ++        E       +     
Sbjct: 349 K-------PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT 401

Query: 753 PKEPSPKQDVVGKTPPSTTVGSHSP--PETPV-LTRSSAQTSAAGATATTSTSSTVTVTA 809
           PKEP+P      K P  TT    SP  P+ P   T  SA T+      TT+ S+  T   
Sbjct: 402 PKEPAP---TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 458

Query: 810 PAPAATGSPVKKQRPLLPKETAPAVQR 836
           P+P  T  P     P  PKE AP   +
Sbjct: 459 PSPTTTKEPA----PTTPKEPAPTTPK 481



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 85/400 (21%), Positives = 134/400 (33%), Gaps = 73/400 (18%)

Query: 491 KSTASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLK 550
           K T  P       +G  +G  K  +P  S   TT+ +K ST+  I               
Sbjct: 118 KPTPKPPVVDEAGSGLDNGDFKVTTPDTS---TTQHNKVSTSPKI--------------- 159

Query: 551 ELSESVQQQSTPVPLISPKRQIRSRFQLNLDK--TIESCKAQLGINEISED-VYTAVEHS 607
               +  +   P P + P         L ++K  T+E+ +      + S D         
Sbjct: 160 ----TTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAK 215

Query: 608 DSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVEIKE 666
           +++  EK+ + D    S    K   + E T         KEP+    K+P  T P E   
Sbjct: 216 ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP 275

Query: 667 ELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLD 726
               ++P + K +P     K++P   K+      P+P   K+      +  +PT      
Sbjct: 276 TTIKSAPTTPK-EPAPTTTKSAPTTPKE------PAPTTTKEPAPTTPKEPAPTT----- 323

Query: 727 SDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRS 786
                                      KEP+P       T P     +      P   + 
Sbjct: 324 --------------------------TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 357

Query: 787 SAQTSAAGATATTSTSSTVTVTAPAPAATGSPV----KKQRPLLPKETAPAVQRVVWNSS 842
            A T+    T TT      T   PAP     P     KK  P  PKE AP   +    ++
Sbjct: 358 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 417

Query: 843 TVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSS 882
           T +      SP+T      T+T+S+P  T   + +T  S+
Sbjct: 418 TKE-----PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA 452



 Score = 53.9 bits (128), Expect = 9e-07
 Identities = 66/283 (23%), Positives = 102/283 (36%), Gaps = 38/283 (13%)

Query: 633 EPEDTEDKEGCQMDKEPSA--VKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASPE 690
           EP  T  KE      + +A    K+P PT P   K   K  +P + K       DK +P 
Sbjct: 671 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPK--KPAPKELAPTTTKGPTSTTSDKPAPT 728

Query: 691 PEKDFSEKAKPSPHPIKDKLKGKDETDSP---TVHLGLDSDSESELVIDLGEDHSGRE-G 746
             K+ +      P P   K       ++P   T  +   + ++    I    D S  E  
Sbjct: 729 TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELS 788

Query: 747 RKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 806
            +   +  E SPK+  V  T            +TP  T+    T+A   T      +T  
Sbjct: 789 AEPTPKALENSPKEPGVPTT------------KTPAATKPEMTTTAKDKTTERDLRTTPE 836

Query: 807 VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTST----ITLVT 862
            T  AP  T            KETA   ++   +  T    ++T + +  T    IT + 
Sbjct: 837 TTTAAPKMT------------KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLK 884

Query: 863 STQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTS 905
           +T  +P VT++    T    +N   P  TA     A  +K T+
Sbjct: 885 TTTLAPKVTTTKKTITTTEIMNK--PEETAKPKDRATNSKATT 925



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 97/434 (22%), Positives = 151/434 (34%), Gaps = 53/434 (12%)

Query: 492 STASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE 551
           +T  PA T T  A +    P P + +  AP T K +   TT         +  A    KE
Sbjct: 440 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPTTPKE 498

Query: 552 LSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSED 611
            + +  ++  P    +PK    +  +    +T  +   +L      +   T  E      
Sbjct: 499 PAPTTTKKPAPT---TPKEPAPTTPK----ETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 551

Query: 612 SEKSDSSDSEYISDDEQKSKNEPEDTEDKEGC-QMDKEPS-AVKKKPKPTNPVEIKEEL- 668
            E+   +  E   +    +  EP  T  K       KEP+    K+P PT P E      
Sbjct: 552 PEELAPTTPE---EPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP 608

Query: 669 KSTSPASEKAD-PGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDS 727
           K T+P + K   P  +K+ A   P+K   ++  P+    K+      +  +PT   G   
Sbjct: 609 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT--TKEPTSTTCDKPAPTTPKGTAP 666

Query: 728 DSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSS 787
            +                       PKEP+P      K P  TT    +P        ++
Sbjct: 667 TT-----------------------PKEPAP---TTPKEPAPTTPKGTAPTTLKEPAPTT 700

Query: 788 AQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQK 847
            +  A    A T+T    + T+  PA T    K+  P  PKE AP   +           
Sbjct: 701 PKKPAPKELAPTTTKGPTSTTSDKPAPT--TPKETAPTTPKEPAPTTPK-----KPAPTT 753

Query: 848 EITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKM 907
             T  P+TS ++  T+T+    +  S   ST   S     P   A  +   +    T+K 
Sbjct: 754 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE---PTPKALENSPKEPGVPTTKT 810

Query: 908 MDAIKGTMTEIYND 921
             A K  MT    D
Sbjct: 811 PAATKPEMTTTAKD 824



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 106/547 (19%), Positives = 172/547 (31%), Gaps = 77/547 (14%)

Query: 387 TPYTPNSQYQMLLDPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLSGGTGRRISL 446
           T  T  +  Q   D    +    +    EK     D+  + K+L +KP     T  +   
Sbjct: 193 TKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK-DLAPTSKVL-AKPTPKAETTTKGPA 250

Query: 447 SDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS 506
              P+ P  T       +  ++       S+  +  E +      +T S  +T    A +
Sbjct: 251 LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA----PTTTKSAPTTPKEPAPT 306

Query: 507 LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLD------RSKAEMDLKELSESVQQQS 560
            +  P P +P+  AP TTK    +TT S      +      +  A    KE + +  ++ 
Sbjct: 307 TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 366

Query: 561 TPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEH----SDSEDSEKSD 616
           TP     P    +        +   +   +       E   T  +     +  E S  + 
Sbjct: 367 TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP 426

Query: 617 SSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS-AVKKKPKPTNPVE------------ 663
              +   +     +  EP  T  K      KEPS    K+P PT P E            
Sbjct: 427 KEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 486

Query: 664 IKEELKSTSP------ASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKD-ET 716
             +E   T+P       ++K  P   K+ A   P++      K       +KL     E 
Sbjct: 487 TPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 546

Query: 717 DSPTVHLGLDSDSESELVIDLGEDHSGREGR----KNKKEPKEPSPKQDVVG-------- 764
            +PT    L   +  E      E+ +    +       KEP   +PK+            
Sbjct: 547 PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPT 606

Query: 765 ------------------KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVT 806
                             K P  TT    +P E    T     ++     A T+   T  
Sbjct: 607 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 666

Query: 807 VTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQS 866
            T   PA T    K+  P  PK TAP         +T+++   T     +   L  +T  
Sbjct: 667 TTPKEPAPT--TPKEPAPTTPKGTAP---------TTLKEPAPTTPKKPAPKELAPTTTK 715

Query: 867 SPLVTSS 873
            P  T+S
Sbjct: 716 GPTSTTS 722



 Score = 38.1 bits (87), Expect = 0.049
 Identities = 55/254 (21%), Positives = 91/254 (35%), Gaps = 36/254 (14%)

Query: 450 PRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSG 509
           P +P  T S V T +       K+ T+ H S  E + +     +A P       +    G
Sbjct: 754 PETPPPTTSEVSTPTTT-----KEPTTIHKSPDESTPEL----SAEPTPKALENSPKEPG 804

Query: 510 SPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLISPK 569
            P   +P  + P  T T K  TT   L    + + A   + + + +  +++T   + +  
Sbjct: 805 VPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATT 864

Query: 570 RQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDEQK 629
            Q+ S        T       L    ++  V T           K   + +E +      
Sbjct: 865 TQVTS---TTTQDTTPFKITTLKTTTLAPKVTTT----------KKTITTTEIM------ 905

Query: 630 SKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKASP 689
             N+PE+T   +    D+  ++    PKP  P   K   K TS    K  P   K K +P
Sbjct: 906 --NKPEETAKPK----DRATNSKATTPKPQKPT--KAPKKPTSTKKPKTMPRVRKPKTTP 957

Query: 690 EPEKDFSEKAKPSP 703
            P K  S   + +P
Sbjct: 958 TPRKMTSTMPELNP 971



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 39/170 (22%), Positives = 64/170 (37%), Gaps = 29/170 (17%)

Query: 744 REGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSS 803
           ++ +KN+ + K+P+PK  VV +       G                      T  TST+ 
Sbjct: 108 KDNKKNRTK-KKPTPKPPVVDEAGSGLDNGDFKV-----------------TTPDTSTTQ 149

Query: 804 TVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTS 863
              V+      T  P+   RP LP  +  + +     S TV ++   ++  T+T    TS
Sbjct: 150 HNKVSTSPKITTAKPINP-RPSLPPNSDTSKE----TSLTVNKETTVETKETTTTNKQTS 204

Query: 864 TQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKG 913
           T      TS+    ++  +   DL      A  +  +AK T K     KG
Sbjct: 205 TDGKEKTTSAKETQSIEKTSAKDL------APTSKVLAKPTPKAETTTKG 248


>gi|38788260 bromodomain PHD finger transcription factor isoform 2
            [Homo sapiens]
          Length = 2903

 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 46/143 (32%), Positives = 67/143 (46%), Gaps = 11/143 (7%)

Query: 123  CELCPRVYHAKCLR-LTSEPE--GDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLK 179
            C+ C   YH +C+  L SE E   ++ CP+C+    A  + T    +T    E L  +L+
Sbjct: 2742 CDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTP---LTEKDYEGLKRVLR 2798

Query: 180  -FAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAK 238
                 KM  P    F +PV     PDY   I  PMDL T+E+  +++ Y     F+AD  
Sbjct: 2799 SLQAHKMAWP----FLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMT 2854

Query: 239  WILHNCIIYNGGNHKLTQIAKVV 261
             I  NC  YN  +    Q A+V+
Sbjct: 2855 KIFDNCRYYNPSDSPFYQCAEVL 2877



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 5/74 (6%)

Query: 108 DFYCWVCHREGQVLCCELCPRVYHAKCLR--LTSEPEGDWFCPEC--EKIT-VAECIETQ 162
           D +C VCH+ G +LCCE C  VYH +C++  L   PE +W C  C   K+  V +C+   
Sbjct: 390 DDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEI 449

Query: 163 SKAMTMLTIEQLSY 176
            K    +  E + Y
Sbjct: 450 QKNKPYIRHEPIGY 463



 Score = 37.7 bits (86), Expect = 0.064
 Identities = 52/238 (21%), Positives = 95/238 (39%), Gaps = 15/238 (6%)

Query: 740 DHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATT 799
           ++  ++  KN++E ++ S ++D   KTP        S   T V  + ++ ++  G   T 
Sbjct: 584 ENDSKDAEKNREEFEDQSLEKDSDDKTPDDDPEQGKSEEPTEVGDKGNSVSANLGDNTTN 643

Query: 800 STSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTIT 859
           +TS     T+P+   +      + P    +++   ++ V +       E       S+ T
Sbjct: 644 ATSEE---TSPSEGRSPVGCLSETP----DSSNMAEKKVASELPQDVPEEPNKTCESSNT 696

Query: 860 LVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIY 919
             T+T   P + +S S S L SS +     A    +   +     S   + +    +E  
Sbjct: 697 SATTTSIQPNLENSNSSSELNSSQSESAKAADDPENGERESHTPVSIQEEIVGDFKSEKS 756

Query: 920 N-DLS------KNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSL 970
           N +LS      K  +GST   I RLR    KL  L  Q+++   H       E ++ L
Sbjct: 757 NGELSESPGAGKGASGST-RIITRLRNPDSKLSQLKSQQVAAAAHEANKLFKEGKEVL 813



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 62/259 (23%), Positives = 96/259 (37%), Gaps = 35/259 (13%)

Query: 660  NPVEIKEELKSTSPASEKADPGAVKDKASPEP---EKDFSEKAKPSPH-PIKDKLKGKDE 715
            N  E K  L S+S A      G  +D     P   E D ++   PS   P  + +   ++
Sbjct: 1605 NSSETKSHLLSSSDAE-----GNYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVED 1659

Query: 716  TDSPTVHLG------LDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPS 769
             +  T  +       + S+ ES L  D   D +G    KN+    E   K  +   T  +
Sbjct: 1660 MEIETSEVKKVTSSPITSEEESNLSNDF-IDENGLPINKNENVNGESKRKTVITEVTTMT 1718

Query: 770  TTVGSHSPPETPVLT--RSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLP 827
            +TV + S     V    + +  +S      +T T++T TVT  +  +TG  V        
Sbjct: 1719 STVATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVD------- 1771

Query: 828  KETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADL 887
                  +  V   S TV    +T S +T+  TLVTS      V+   S    V  +    
Sbjct: 1772 ------IISVKEQSKTVVTTTVTDSLTTTGGTLVTSM----TVSKEYSTRDKVKLMKFSR 1821

Query: 888  PIATASADVAADIAKYTSK 906
            P  T S        K+ +K
Sbjct: 1822 PKKTRSGTALPSYRKFVTK 1840


>gi|38788274 bromodomain PHD finger transcription factor isoform 1
            [Homo sapiens]
          Length = 2920

 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 46/143 (32%), Positives = 67/143 (46%), Gaps = 11/143 (7%)

Query: 123  CELCPRVYHAKCLR-LTSEPE--GDWFCPECEKITVAECIETQSKAMTMLTIEQLSYLLK 179
            C+ C   YH +C+  L SE E   ++ CP+C+    A  + T    +T    E L  +L+
Sbjct: 2759 CDRCQNWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMTVLTP---LTEKDYEGLKRVLR 2815

Query: 180  -FAIQKMKQPGTDAFQKPVPLEQHPDYAEYIFHPMDLCTLEKNAKKKMYGCTEAFLADAK 238
                 KM  P    F +PV     PDY   I  PMDL T+E+  +++ Y     F+AD  
Sbjct: 2816 SLQAHKMAWP----FLEPVDPNDAPDYYGVIKEPMDLATMEERVQRRYYEKLTEFVADMT 2871

Query: 239  WILHNCIIYNGGNHKLTQIAKVV 261
             I  NC  YN  +    Q A+V+
Sbjct: 2872 KIFDNCRYYNPSDSPFYQCAEVL 2894



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 5/74 (6%)

Query: 108 DFYCWVCHREGQVLCCELCPRVYHAKCLR--LTSEPEGDWFCPEC--EKIT-VAECIETQ 162
           D +C VCH+ G +LCCE C  VYH +C++  L   PE +W C  C   K+  V +C+   
Sbjct: 390 DDHCRVCHKLGDLLCCETCSAVYHLECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCVAEI 449

Query: 163 SKAMTMLTIEQLSY 176
            K    +  E + Y
Sbjct: 450 QKNKPYIRHEPIGY 463



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 51/258 (19%), Positives = 104/258 (40%), Gaps = 16/258 (6%)

Query: 752  EPKEPS-PKQDVVGKTPPSTTVGSHSPPET-PVLTRSSAQTSAAGATATTSTSSTVTVTA 809
            +P+ P+ P+     +    TTV SH P E  P   +SS    AA +   ++      V  
Sbjct: 2284 QPQSPAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQSSKPQVAAQSQPQSNVQGQSPVRV 2343

Query: 810  PAPAATGSPVKKQRPLLPKETAPAVQRVVWNSST----VQQKEITQSPSTSTITLVTSTQ 865
             +P+ T     + RP  P + +P  Q  V  +++    +Q     Q PS          Q
Sbjct: 2344 QSPSQT-----RIRPSTPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPSQGQPQSQPQVQ 2398

Query: 866  SSPLVTSSG---SMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDL 922
            SS    SSG   +  T+ S     L I      V A       + +  +    +++   +
Sbjct: 2399 SSTQTLSSGQTLNQVTVSSPSRPQLQIQQPQPQVIA--VPQLQQQVQVLSQIQSQVVAQI 2456

Query: 923  SKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVK 982
                +G       +L I+I++   +   ++  +      ++ E  Q ++Q RD+   + +
Sbjct: 2457 QAQQSGVPQQIKLQLPIQIQQSSAVQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQKKKQ 2516

Query: 983  KQLELEKQQAVDETKKKQ 1000
            +Q+E++++  +  + + +
Sbjct: 2517 QQIEIKREHTLQASNQSE 2534



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 62/259 (23%), Positives = 96/259 (37%), Gaps = 35/259 (13%)

Query: 660  NPVEIKEELKSTSPASEKADPGAVKDKASPEP---EKDFSEKAKPSPH-PIKDKLKGKDE 715
            N  E K  L S+S A      G  +D     P   E D ++   PS   P  + +   ++
Sbjct: 1479 NSSETKSHLLSSSDAE-----GNYRDSLETLPSTKESDSTQTTTPSASCPESNSVNQVED 1533

Query: 716  TDSPTVHLG------LDSDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPS 769
             +  T  +       + S+ ES L  D   D +G    KN+    E   K  +   T  +
Sbjct: 1534 MEIETSEVKKVTSSPITSEEESNLSNDF-IDENGLPINKNENVNGESKRKTVITEVTTMT 1592

Query: 770  TTVGSHSPPETPVLT--RSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLP 827
            +TV + S     V    + +  +S      +T T++T TVT  +  +TG  V        
Sbjct: 1593 STVATESKTVIKVEKGDKQTVVSSTENCAKSTVTTTTTTVTKLSTPSTGGSVD------- 1645

Query: 828  KETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADL 887
                  +  V   S TV    +T S +T+  TLVTS      V+   S    V  +    
Sbjct: 1646 ------IISVKEQSKTVVTTTVTDSLTTTGGTLVTSM----TVSKEYSTRDKVKLMKFSR 1695

Query: 888  PIATASADVAADIAKYTSK 906
            P  T S        K+ +K
Sbjct: 1696 PKKTRSGTALPSYRKFVTK 1714


>gi|51599156 chromodomain helicase DNA binding protein 4 [Homo
           sapiens]
          Length = 1912

 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 36/107 (33%), Positives = 51/107 (47%), Gaps = 17/107 (15%)

Query: 48  SSNGHSPQDTSTSPIKKKKKPGLLNSNNKEQSELRHGPFYYMKQPLTTDPVDVVPQDGRN 107
           S N +S  D STS   + +K  L  +  K++ E         ++    D  +   QD   
Sbjct: 325 SINSYSVSDGSTSRSSRSRKK-LRTTKKKKKGE---------EEVTAVDGYETDHQD--- 371

Query: 108 DFYCWVCHREGQVLCCELCPRVYHAKCL--RLTSEPEGDWFCPECEK 152
             YC VC + G+++ C+ CPR YH  CL   +   PEG W CP CEK
Sbjct: 372 --YCEVCQQGGEIILCDTCPRAYHMVCLDPDMEKAPEGKWSCPHCEK 416



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 22/54 (40%), Positives = 30/54 (55%), Gaps = 2/54 (3%)

Query: 99  DVVPQDGRNDFYCWVCHREGQVLCCELCPRVYHAKCLR--LTSEPEGDWFCPEC 150
           D+  +D  +  +C VC   G++LCC+ CP  YH  CL   L   P G+W CP C
Sbjct: 440 DLEEEDDHHMEFCRVCKDGGELLCCDTCPSSYHIHCLNPPLPEIPNGEWLCPRC 493



 Score = 37.7 bits (86), Expect = 0.064
 Identities = 53/242 (21%), Positives = 95/242 (39%), Gaps = 36/242 (14%)

Query: 606 HSDSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTN---PV 662
           H ++E+  + D S++E     ++K   +P D +  +  +  KE   + ++   ++   P 
Sbjct: 32  HPENEEDPEEDLSETETPKLKKKKKPKKPRDPKIPKSKRQKKERMLLCRQLGDSSGEGPE 91

Query: 663 EIKEE----LKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDS 718
            ++EE    L+S S  S+       K K  P+ EK    K K      +++ +  D+ DS
Sbjct: 92  FVEEEEEVALRSDSEGSDYTPGKKKKKKLGPKKEKKSKSKRK------EEEEEEDDDDDS 145

Query: 719 PTVHLGLDSDSESELVIDLG----------EDHSGREGRKNKKEPKEP--SPKQDVVGKT 766
                  +  S ++L+ D G          ED+      K   +   P  + K   +  +
Sbjct: 146 K------EPKSSAQLLEDWGMEDIDHVFSEEDYRTLTNYKAFSQFVRPLIAAKNPKIAVS 199

Query: 767 PPSTTVGS---HSPPETPVLTRSSAQTSAAGATATTSTSSTVTVT--APAPAATGSPVKK 821
                +G+         P    S A  +AA A A     S VT T  AP P     P++K
Sbjct: 200 KMMMVLGAKWREFSTNNPFKGSSGASVAAAAAAAVAVVESMVTATEVAPPPPPVEVPIRK 259

Query: 822 QR 823
            +
Sbjct: 260 AK 261


>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
            sapiens]
          Length = 1521

 Score = 62.0 bits (149), Expect = 3e-09
 Identities = 82/406 (20%), Positives = 147/406 (36%), Gaps = 26/406 (6%)

Query: 742  SGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTST 801
            +G E      E  E +       +T   +T GS +   T   T  S  T+ + A +  +T
Sbjct: 549  TGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT---TAASTAGSETTTVSTADSENTT 605

Query: 802  SSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLV 861
            +ST      + + TGS            TA         +ST   +  T S + S  T+V
Sbjct: 606  ASTADSETTSASTTGSETT---------TASTTSSETTTASTEGSETTTVSTTDSETTMV 656

Query: 862  TSTQSSPLVTSS-GSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYN 920
            ++T S   +TS+ GS +T VS+  ++  ++T  +         +     +  G+ T I +
Sbjct: 657  STTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITS 716

Query: 921  DLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAE 980
                  T ++I          E  +            +   T +E   +     +  +A 
Sbjct: 717  TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776

Query: 981  VKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSA 1040
            +    E      +     K   A+ K   +F     T+       +        S   S 
Sbjct: 777  IMGS-ETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASET----TTVSTAGSE 831

Query: 1041 TAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGS 1100
            T P   A +E  T T  + S+ +++ST+ + + TAS    + T+A       +T    GS
Sbjct: 832  TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 891

Query: 1101 RETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTK 1146
              T +S        ++ S +  +S   S+    ST     T+ ST+
Sbjct: 892  ETTTTS--------TEGSETTTASTEGSEITTVSTTGSETTTASTE 929



 Score = 53.9 bits (128), Expect = 9e-07
 Identities = 141/739 (19%), Positives = 262/739 (35%), Gaps = 52/739 (7%)

Query: 440  TGRRISLSDMPRSPMSTNSSVHTGSDVEQDA-EKKATSSHFSASEESMDFL----DKSTA 494
            TG   + +    S M+T S+  TG++   D+ E   T++  +A  E+        + +TA
Sbjct: 549  TGLETTTTSTEGSEMTTVST--TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 606

Query: 495  SPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE--L 552
            S A ++T  A S +GS    +   S+  TT + + S T ++   + + +       E  +
Sbjct: 607  STADSETTSA-STTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665

Query: 553  SESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDS 612
            + +   ++T V     +  + +        +I   +        SE   T+ E S+   +
Sbjct: 666  TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEGSEITTA 725

Query: 613  EKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTS 672
              + S  +   ++  + +    E +E         E +        T    I      T+
Sbjct: 726  SITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS--ETT 783

Query: 673  PASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESE 732
             AS           AS +    F+E ++ +       +     +++ TV     + SE+ 
Sbjct: 784  MASTIGSETTKVSTASSKMTTVFTENSETT-------IASTTASETTTVST---AGSETI 833

Query: 733  LVIDLGEDHS------GREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRS 786
                 G + +      G E      E  E +       +T  +TT+GS +   T   T  
Sbjct: 834  PASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET---TTASTEG 890

Query: 787  SAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQ-RVVWNSSTVQ 845
            S  T+ +   + T+T+ST        + TGS          + T  + +   +   ST  
Sbjct: 891  SETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG 950

Query: 846  QKEITQSPSTSTITLVTSTQSSPLVTSS-GSMSTLVSSVNADLPIATASADVAADIAKYT 904
             + IT S   S  T VT+  S     S+ GS +T VS+  ++   A+        ++   
Sbjct: 951  SETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1010

Query: 905  SKMMD-AIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTM 963
            S+    +  GT T I +     TT  T A      +     +             +  T 
Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070

Query: 964  AEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYP 1023
            +E   +   + +                A  ET             ++     T+     
Sbjct: 1071 SETTTASTADLETTTVSTSGSGTTTASTAGSETT-----------TVYITGSKTTTASTE 1119

Query: 1024 CQQAHWPEHMKSCTQSATAPQQEADAEVNT--ETLNKSSQGSSSSTQSAPSE--TASASK 1079
              +A       S T +A+    E      T  ET   S+ GS ++T SA     T ++++
Sbjct: 1120 GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE 1179

Query: 1080 EKETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTR--- 1136
              ET+   +  S +T   +   ET ++   GS   +  +  +++S  SS     +T    
Sbjct: 1180 GSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFII 1239

Query: 1137 SDHNTSTSTKSLLPKESRL 1155
                T  ST SL P  + L
Sbjct: 1240 GSETTIASTASLEPTATSL 1258



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 77/402 (19%), Positives = 151/402 (37%), Gaps = 45/402 (11%)

Query: 765  KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRP 824
            +T  ++T GS +   +P  ++++  + +     TTST+ +   T  +  +  +       
Sbjct: 34   ETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGS 93

Query: 825  LLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVN 884
                 TA +    V  S T  +  +  +  + T T  T++  + + +++GS +T VS+V 
Sbjct: 94   ETTVSTAGSETTTV--SITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVG 151

Query: 885  ADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKL 944
            ++   A  +AD     A  T          MT ++   S+  T ST         E   +
Sbjct: 152  SETTTA-YTADSETTAASTTG-------SEMTTVFTAGSETITPSTAGS------ETTTV 197

Query: 945  QWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCAN 1004
                 +  +      E T A    S       + +E  K      +  V     +   A+
Sbjct: 198  STAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAAS 257

Query: 1005 CKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSS 1064
             +         NT++           E  K+ T S T  +  A +   +E    S+ GS 
Sbjct: 258  TEDSET-----NTAF----------TEDSKTTTASTTGFETTAASTTGSEPTMASTMGSE 302

Query: 1065 S-------------STQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGS 1111
            +             ST S+   T  A+  +   A       +T+  +GS  T +SI +GS
Sbjct: 303  TTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASI-MGS 361

Query: 1112 NQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKES 1153
               +D +  ++++ +S++    +T S   +  +T S    E+
Sbjct: 362  ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSET 403



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 116/563 (20%), Positives = 190/563 (33%), Gaps = 76/563 (13%)

Query: 400  DPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLS--GGTGRRISLSDMPRSPMSTN 457
            D  N +A TA  +         + T +          S  G     +S +D   + +ST 
Sbjct: 600  DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659

Query: 458  SSVHTGSDVE--QDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGS--------- 506
             S  T +  E  +     AT S  + S E       S     +TK    GS         
Sbjct: 660  GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTITSTEG 719

Query: 507  -------LSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE-------- 551
                   ++GS    +    +  TT + + S T S      + + A     E        
Sbjct: 720  SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 779

Query: 552  ----LSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHS 607
                ++ ++  ++T V   S K  + + F  N + TI S  A       SE   T V  +
Sbjct: 780  SETTMASTIGSETTKVSTASSK--MTTVFTENSETTIASTTA-------SET--TTVSTA 828

Query: 608  DSEDSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEE 667
             SE    S +      +   + S+     TE  E      E S      + T    I  E
Sbjct: 829  GSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESS------ETTTATTIGSE 882

Query: 668  LKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDS 727
              + S    +    + +   +     + SE    S    +      + +++ T      S
Sbjct: 883  TTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTA-----S 937

Query: 728  DSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSS 787
               SEL        +G E      E  E +    +  +T  ++T GS    ET  ++ + 
Sbjct: 938  TEGSELTT---VSTTGSETITVSAEGSETTTVTTMGSETTTASTAGS----ETTTVSTAG 990

Query: 788  AQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQK 847
            ++T+    TA+   S T TV++     TGS          + T  + +     + T    
Sbjct: 991  SETT----TASIEGSETTTVSS-----TGSETTTVSTTGTETTITSTEGSETTTVTTAGS 1041

Query: 848  EITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKM 907
            E T   +T + T  TST+ S   T S + S   ++  ADL   T S   +      T+  
Sbjct: 1042 ETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTA-- 1099

Query: 908  MDAIKGTMTEIYNDLSKNTTGST 930
                    T +Y   SK TT ST
Sbjct: 1100 ----GSETTTVYITGSKTTTAST 1118



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 133/752 (17%), Positives = 262/752 (34%), Gaps = 87/752 (11%)

Query: 434  PVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKST 493
            P  +G     +S +    + +ST  S  T +     A  + T++    SE +     K +
Sbjct: 187  PSTAGSETTTVSTAGSETTTVSTTGSETTTAST---AHSETTAASTMGSETT-----KVS 238

Query: 494  ASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELS 553
             + + T    AGS + +      + +   T   D  +TT S        +        ++
Sbjct: 239  TAGSETTVSTAGSETTAASTEDSETNTAFTE--DSKTTTASTTGFETTAASTTGSEPTMA 296

Query: 554  ESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSE 613
             ++  ++T    I P+    S     +     +    +  + +  +  T V  + SE + 
Sbjct: 297  STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET-TTVSTTGSETTT 355

Query: 614  KSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS---AVKKKPKPTNPVEIKEELKS 670
             S    SE  +D    S+     TE  E      E S    V      T  V I +  ++
Sbjct: 356  ASIMG-SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS-ET 413

Query: 671  TSPASEKADPGAVKDKA--SPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSD 728
            T+  +E ++  AV      +     + SE    S    +      + +++ TV     + 
Sbjct: 414  TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTV---TTAG 470

Query: 729  SESELVIDLGED-----HSGRE-------GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHS 776
            SE++     G +     ++G E       G        E S    V       TTV +  
Sbjct: 471  SETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530

Query: 777  PPETPVLTRSSAQTSAAGATATTSTSST----VTVTAPAPAATGSPVKKQRPLLPKETAP 832
               T V T  S  T+ +     T+T+ST    +T  +   A T +   +        TA 
Sbjct: 531  SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAG 590

Query: 833  AVQRVVWNS------STVQQKEITQSPSTSTITLVTSTQSSPLVTSS--GSMSTLVSSVN 884
            +    V  +      ++    E T + +T + T   ST SS   T+S  GS +T VS+ +
Sbjct: 591  SETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTD 650

Query: 885  ADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKL 944
            ++  + + +       +   S+       T++   ++ + +T GS    +     E  K+
Sbjct: 651  SETTMVSTTGSERTITSTEGSETT-----TVSATGSETTVSTEGSGTTTVSITGSETTKV 705

Query: 945  QWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCAN 1004
                 +         E+T A +  S     +   A  +            ET       +
Sbjct: 706  STTGSETTITSTEGSEITTASITGS-----ETTTASTEGSETTTASTEGSETTSASTTGS 760

Query: 1005 CKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSS 1064
                                         ++ T S T+ +    + + +ET   S+ GS 
Sbjct: 761  -----------------------------ETTTASTTSSETTMASIMGSETTMASTIGSE 791

Query: 1065 S---STQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSN 1121
            +   ST S+   T      + T A  +    +T+  +GS   P+S        +  +  +
Sbjct: 792  TTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGS 851

Query: 1122 KSSWSSSDEKRGSTRSDHNTSTSTKSLLPKES 1153
            +++ +S++    +T S  ++ T+T + +  E+
Sbjct: 852  ETTTASTEGSETTTASTESSETTTATTIGSET 883



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 82/400 (20%), Positives = 156/400 (39%), Gaps = 39/400 (9%)

Query: 760  QDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPV 819
            +  V      TT  S +  ET +++   ++T+     +TTS+ +TVT TA +   T S V
Sbjct: 94   ETTVSTAGSETTTVSITGTETTMVSAMGSETTT---NSTTSSETTVTSTAGSETTTVSTV 150

Query: 820  KKQRP---LLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSM 876
              +         ET  A       S+T  +     +  + TIT  T+   +  V+++GS 
Sbjct: 151  GSETTTAYTADSETTAA-------STTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSE 203

Query: 877  STLVSSVNADLPIAT---ASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGST-IA 932
            +T VS+  ++   A+   +    A+ +   T+K+  A  G+ T +    S+ T  ST  +
Sbjct: 204  TTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA--GSETTVSTAGSETTAASTEDS 261

Query: 933  EIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQA 992
            E      E  K         +      E T A    S       + + +  +  +     
Sbjct: 262  ETNTAFTEDSK-------TTTASTTGFETTAA----STTGSEPTMASTMGSETTMASTIG 310

Query: 993  VDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSAT--APQQEADAE 1050
             + TK     A+ +   +F     T        +        S T +A+    +   D+ 
Sbjct: 311  PETTKVS--TASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDST 368

Query: 1051 VNTETLNKSSQGS---SSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRET--PS 1105
              +ET   S++GS   ++ST+ + + T S +  + T+   +    +T    GS  T   +
Sbjct: 369  TGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVST 428

Query: 1106 SILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTST 1145
            ++   +   ++ S    +S S S+    ST     T+ +T
Sbjct: 429  TVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTT 468



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 92/473 (19%), Positives = 169/473 (35%), Gaps = 24/473 (5%)

Query: 432  SKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDK 491
            S+   +  TG   + +    S  +  S + + + +      + T    ++S+ +  F + 
Sbjct: 750  SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 809

Query: 492  STASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGS-ILNLNLDRSKAEMDLK 550
            S  + AST   +  ++S +     P  +A   T T  TST GS     + + S+      
Sbjct: 810  SETTIASTTASETTTVSTAGSETIPASTAGSETTTT-TSTEGSETTTASTEGSETTTAST 868

Query: 551  ELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSE 610
            E SE+    +T   + S      +        + E  +      E SE   T V  + SE
Sbjct: 869  ESSET----TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSE--ITTVSTTGSE 922

Query: 611  DSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS----AVKKKPKPTNPVEIKE 666
             +  S +  SE  +   + S+     T   E   +  E S          + T       
Sbjct: 923  TTTAS-TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGS 981

Query: 667  ELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLD 726
            E  + S A  +    +++   +       SE    S    +  +   + +++ TV     
Sbjct: 982  ETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTV---TT 1038

Query: 727  SDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPP--STTVGSHSPPETPVLT 784
            + SE+  V   G + +      ++      +  +     T    +TTV +     T   T
Sbjct: 1039 AGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098

Query: 785  RSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTV 844
              S  T+     + T+T+ST    A   + T S          + T   V   V  ++TV
Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT--TVFTTVSETTTV 1156

Query: 845  QQ--KEITQSPSTSTITLVTSTQSSPLVTSS--GSMSTLVSSVNADLPIATAS 893
                 E T S +  +    TST+ S   T+S  GS +T  S+  ++   A+ S
Sbjct: 1157 STIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS 1209



 Score = 33.9 bits (76), Expect = 0.92
 Identities = 34/166 (20%), Positives = 72/166 (43%), Gaps = 12/166 (7%)

Query: 763  VGKTPPSTTVGSHSPPE-------TPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAAT 815
            V +T   +T+GS +          T   T  S  T+A+ A + T+T+ST        + +
Sbjct: 1150 VSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS 1209

Query: 816  GSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTS---TITLVTSTQSSPLVTS 872
            GS          + + P+      N++ +   E T + + S   T T +T ++++ +  +
Sbjct: 1210 GSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSIT 1269

Query: 873  SGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEI 918
            +   +   ++V++   + T + DV+  I   T+  M   + T T +
Sbjct: 1270 ASGATAASTTVSSTTFVLTKATDVS--IQPITNTPMSGTRTTGTRL 1313



 Score = 33.9 bits (76), Expect = 0.92
 Identities = 49/229 (21%), Positives = 82/229 (35%), Gaps = 37/229 (16%)

Query: 729  SESELVIDLGEDHS-----GREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSH-------- 775
            SE+  V  +G + +     G E      E  E +       +T  ++T GS         
Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210

Query: 776  SPPETPVLTRSSAQTSAAGATAT---------TSTSSTVTVTAPAPAATGS-----PVKK 821
            S   T   T S   T ++  + T         T+ +ST ++   A + TGS      +  
Sbjct: 1211 SETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITA 1270

Query: 822  QRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVS 881
                    T  +   V+  ++ V  + IT +P + T T  T   +S  VT +  M    S
Sbjct: 1271 SGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTAS 1330

Query: 882  SVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGST 930
            + +  +P           I   TS +  +  G  +       + TTGST
Sbjct: 1331 AASHTVP----------GIVLNTSGLGTSTMGASSTTSAHGVRTTTGST 1369


>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1531

 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 81/406 (19%), Positives = 146/406 (35%), Gaps = 26/406 (6%)

Query: 742  SGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTST 801
            +G E      E  E +       +T   +T GS +   T   T  S  T+ + A +  +T
Sbjct: 549  TGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT---TAASTAGSETTTVSTADSENTT 605

Query: 802  SSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLV 861
            +ST      + + TGS            TA         +ST   +  T S + S  T+V
Sbjct: 606  ASTADSETTSASTTGSETT---------TASTTSSETTTASTEGSETTTVSTTDSETTMV 656

Query: 862  TSTQSSPLVTSS-GSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYN 920
            ++T S   +TS+ GS +T VS+  ++  ++T  +         +     +  G+ T   +
Sbjct: 657  STTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTS 716

Query: 921  DLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAE 980
                  T ++I          E  +            +   T +E   +     +  +A 
Sbjct: 717  TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776

Query: 981  VKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSA 1040
            +    E      +     K   A+ K   +F     T+       +        S   S 
Sbjct: 777  IMGS-ETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASET----TTVSTAGSE 831

Query: 1041 TAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGS 1100
            T P   A +E  T T  + S+ +++ST+ + + TAS    + T+A       +T    GS
Sbjct: 832  TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 891

Query: 1101 RETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTK 1146
              T +S        ++ S +  +S   S+    ST     T+ ST+
Sbjct: 892  ETTTTS--------TEGSETTTASTEGSEITTVSTTGSETTTASTE 929



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 136/736 (18%), Positives = 264/736 (35%), Gaps = 49/736 (6%)

Query: 440  TGRRISLSDMPRSPMSTNSSVHTGSDVEQDA-EKKATSSHFSASEESMDFL----DKSTA 494
            TG   + +    S M+T S+  TG++   D+ E   T++  +A  E+        + +TA
Sbjct: 549  TGLETTTTSTEGSEMTTVST--TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 606

Query: 495  SPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE--L 552
            S A ++T  A S +GS    +   S+  TT + + S T ++   + + +       E  +
Sbjct: 607  STADSETTSA-STTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665

Query: 553  SESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDS 612
            + +   ++T V     +  + +        +I   +        SE   T+ E S+   +
Sbjct: 666  TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTA 725

Query: 613  EKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTS 672
              + S  +   ++  + +    E +E         E +        T    I      T+
Sbjct: 726  SITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS--ETT 783

Query: 673  PASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESE 732
             AS           AS +    F+E ++ +       +     +++ TV     + SE+ 
Sbjct: 784  MASTIGSETTKVSTASSKMTTVFTENSETT-------IASTTASETTTVST---AGSETI 833

Query: 733  LVIDLGEDHS------GREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRS 786
                 G + +      G E      E  E +       +T  +TT+GS +   T   T  
Sbjct: 834  PASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET---TTASTEG 890

Query: 787  SAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQ-RVVWNSSTVQ 845
            S  T+ +   + T+T+ST        + TGS          + T  + +   +   ST  
Sbjct: 891  SETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG 950

Query: 846  QKEITQSPSTSTITLVTSTQSSPLVTSS-GSMSTLVSSVNADLPIATASADVAADIAKYT 904
             + IT S   S  T VT+  S     S+ GS +T VS+  ++   A+        ++   
Sbjct: 951  SETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1010

Query: 905  SKMMD-AIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTM 963
            S+    +  GT T I +     TT  T A      +     +             +  T 
Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070

Query: 964  AEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYP 1023
            +E   +   + +                A  ET             ++     T+     
Sbjct: 1071 SETTTASTADLETTTVSTSGSGTTTASTAGSETT-----------TVYITGSKTTTASTE 1119

Query: 1024 CQQAHWPEHMKSCTQSATAPQQEADAEVNT--ETLNKSSQGSSSSTQSAPSE--TASASK 1079
              +A       S T +A+    E      T  ET   S+ GS ++T SA     T ++++
Sbjct: 1120 GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE 1179

Query: 1080 EKETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDH 1139
              ET+   +  S +T   +   ET ++   GS   +  +  ++++ + +     ST S  
Sbjct: 1180 GSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSA 1239

Query: 1140 NTSTSTKSLLPKESRL 1155
             + T+T  ++  E+ +
Sbjct: 1240 GSETNTAFIIGSETTI 1255



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 77/402 (19%), Positives = 151/402 (37%), Gaps = 45/402 (11%)

Query: 765  KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRP 824
            +T  ++T GS +   +P  ++++  + +     TTST+ +   T  +  +  +       
Sbjct: 34   ETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGS 93

Query: 825  LLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVN 884
                 TA +    V  S T  +  +  +  + T T  T++  + + +++GS +T VS+V 
Sbjct: 94   ETTVSTAGSETTTV--SITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVG 151

Query: 885  ADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKL 944
            ++   A  +AD     A  T          MT ++   S+  T ST         E   +
Sbjct: 152  SETTTA-YTADSETTAASTTG-------SEMTTVFTAGSETITPSTAGS------ETTTV 197

Query: 945  QWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCAN 1004
                 +  +      E T A    S       + +E  K      +  V     +   A+
Sbjct: 198  STAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAAS 257

Query: 1005 CKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSS 1064
             +         NT++           E  K+ T S T  +  A +   +E    S+ GS 
Sbjct: 258  TEDSET-----NTAF----------TEDSKTTTASTTGFETTAASTTGSEPTMASTMGSE 302

Query: 1065 S-------------STQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGS 1111
            +             ST S+   T  A+  +   A       +T+  +GS  T +SI +GS
Sbjct: 303  TTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASI-MGS 361

Query: 1112 NQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKES 1153
               +D +  ++++ +S++    +T S   +  +T S    E+
Sbjct: 362  ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSET 403



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 111/555 (20%), Positives = 187/555 (33%), Gaps = 60/555 (10%)

Query: 400  DPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLS--GGTGRRISLSDMPRSPMSTN 457
            D  N +A TA  +         + T +          S  G     +S +D   + +ST 
Sbjct: 600  DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659

Query: 458  SSVHTGSDVE--QDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFS 515
             S  T +  E  +     AT S  + S E       S     +TK    GS + +     
Sbjct: 660  GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEG 719

Query: 516  PQLSAPITTKTDKTS--------TTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLIS 567
             +++    T ++ T+        TT S        +         + +   ++T   ++ 
Sbjct: 720  SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 779

Query: 568  PKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDE 627
             +  + S   +  + T  S  +       +E+  T +  + + ++    ++ SE I    
Sbjct: 780  SETTMAST--IGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAST 837

Query: 628  QKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKA 687
              S  E   T   EG +     ++ +     T   E  E   +T+  SE          A
Sbjct: 838  AGS--ETTTTTSTEGSETTT--ASTEGSETTTASTESSETTTATTIGSETTT-------A 886

Query: 688  SPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHS--GRE 745
            S E  +  +   +           G + T + T        SE   V   G + +    E
Sbjct: 887  STEGSETTTTSTE-----------GSETTTAST------EGSEITTVSTTGSETTTASTE 929

Query: 746  GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGA---TATTSTS 802
            G +      E S    V      + TV +     T V T  S  T+A+ A   T T ST+
Sbjct: 930  GSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTA 989

Query: 803  STVTVTAPAP-------AATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPST 855
             + T TA          ++TGS          + T  + +     + T    E T   +T
Sbjct: 990  GSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTT 1049

Query: 856  STITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTM 915
             + T  TST+ S   T S + S   ++  ADL   T S   +      T+          
Sbjct: 1050 GSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTA------GSET 1103

Query: 916  TEIYNDLSKNTTGST 930
            T +Y   SK TT ST
Sbjct: 1104 TTVYITGSKTTTAST 1118



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 133/752 (17%), Positives = 263/752 (34%), Gaps = 87/752 (11%)

Query: 434  PVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKST 493
            P  +G     +S +    + +ST  S  T +     A  + T++    SE +     K +
Sbjct: 187  PSTAGSETTTVSTAGSETTTVSTTGSETTTAST---AHSETTAASTMGSETT-----KVS 238

Query: 494  ASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELS 553
             + + T    AGS + +      + +   T   D  +TT S        +        ++
Sbjct: 239  TAGSETTVSTAGSETTAASTEDSETNTAFTE--DSKTTTASTTGFETTAASTTGSEPTMA 296

Query: 554  ESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSE 613
             ++  ++T    I P+    S     +     +    +  + +  +  T V  + SE + 
Sbjct: 297  STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET-TTVSTTGSETTT 355

Query: 614  KSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS---AVKKKPKPTNPVEIKEELKS 670
             S    SE  +D    S+     TE  E      E S    V      T  V I +  ++
Sbjct: 356  ASIMG-SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS-ET 413

Query: 671  TSPASEKADPGAVKDKA--SPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSD 728
            T+  +E ++  AV      +     + SE    S    +      + +++ TV     + 
Sbjct: 414  TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTV---TTAG 470

Query: 729  SESELVIDLGED-----HSGRE-------GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHS 776
            SE++     G +     ++G E       G        E S    V       TTV +  
Sbjct: 471  SETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530

Query: 777  PPETPVLTRSSAQTSAAGATATTSTSST----VTVTAPAPAATGSPVKKQRPLLPKETAP 832
               T V T  S  T+ +     T+T+ST    +T  +   A T +   +        TA 
Sbjct: 531  SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAG 590

Query: 833  AVQRVVWNS------STVQQKEITQSPSTSTITLVTSTQSSPLVTSS--GSMSTLVSSVN 884
            +    V  +      ++    E T + +T + T   ST SS   T+S  GS +T VS+ +
Sbjct: 591  SETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTD 650

Query: 885  ADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKL 944
            ++  + + +       +   S+       T++   ++ + +T GS    +     E  K+
Sbjct: 651  SETTMVSTTGSERTITSTEGSETT-----TVSATGSETTVSTEGSGTTTVSITGSETTKV 705

Query: 945  QWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCAN 1004
                 +  +      E+T A +  S     +   A  +            ET       +
Sbjct: 706  STTGSETTTTSTEGSEITTASITGS-----ETTTASTEGSETTTASTEGSETTSASTTGS 760

Query: 1005 CKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSS 1064
                                         ++ T S T+ +    + + +ET   S+ GS 
Sbjct: 761  -----------------------------ETTTASTTSSETTMASIMGSETTMASTIGSE 791

Query: 1065 S---STQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSN 1121
            +   ST S+   T      + T A  +    +T+  +GS   P+S        +  +  +
Sbjct: 792  TTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGS 851

Query: 1122 KSSWSSSDEKRGSTRSDHNTSTSTKSLLPKES 1153
            +++ +S++    +T S  ++ T+T + +  E+
Sbjct: 852  ETTTASTEGSETTTASTESSETTTATTIGSET 883



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 135/719 (18%), Positives = 240/719 (33%), Gaps = 51/719 (7%)

Query: 437  SGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASP 496
            +G     +S +D   +  ST  S  T +         A+++    +  S +  + +T S 
Sbjct: 589  AGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVST 648

Query: 497  ASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESV 556
              ++T    S +GS +  +    +  TT     S TGS   ++ + S         SE+ 
Sbjct: 649  TDSETTMV-STTGSERTITSTEGSETTT----VSATGSETTVSTEGSGTTTVSITGSETT 703

Query: 557  QQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSD 616
            +  +T     S      +        +I   +      E SE    + E S++  +  + 
Sbjct: 704  KVSTTG----SETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTG 759

Query: 617  SSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPV--EIKEELKSTSPA 674
            S  +   +   + +      +E      +  E + V         V  E  E   +++ A
Sbjct: 760  SETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTA 819

Query: 675  SEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELV 734
            SE         +  P      SE    +     +      E    T      S++ +   
Sbjct: 820  SETTTVSTAGSETIPASTAG-SETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878

Query: 735  IDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAG 794
            I      +  EG +      E S       +    TTV +     T   T  S  T+A+ 
Sbjct: 879  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938

Query: 795  -----ATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEI 849
                  T +T+ S T+TV+A     T              TA          ST   +  
Sbjct: 939  EGSELTTVSTTGSETITVSAEGSETTTVTTMGSETT----TASTAGSETTTVSTAGSETT 994

Query: 850  TQSPSTSTITLVTSTQS-SPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMM 908
            T S   S  T V+ST S +  V+++G+ +T+ S+  ++    T +       A YT+   
Sbjct: 995  TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETT--AVYTTGSE 1052

Query: 909  DAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQ 968
                 T TE     + +TTGS         +E   +        +      E T   +  
Sbjct: 1053 TTT--TSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITG 1110

Query: 969  SLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAH 1028
            S                E  +   V  T  +   A+     +       S          
Sbjct: 1111 S---------KTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVS---------- 1151

Query: 1029 WPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKS 1088
              E     T  + A    A     T T  + S+ +++ST  + + TAS +  + T+A  +
Sbjct: 1152 --ETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTA 1209

Query: 1089 KESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWS---SSDEKRGSTRSDHNTSTS 1144
                +T   SGS ET ++   GS   +  S  ++++ +    S+    ST S   T+TS
Sbjct: 1210 GSETTTASTSGS-ETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATS 1267



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 82/400 (20%), Positives = 156/400 (39%), Gaps = 39/400 (9%)

Query: 760  QDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPV 819
            +  V      TT  S +  ET +++   ++T+     +TTS+ +TVT TA +   T S V
Sbjct: 94   ETTVSTAGSETTTVSITGTETTMVSAMGSETTT---NSTTSSETTVTSTAGSETTTVSTV 150

Query: 820  KKQRP---LLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSM 876
              +         ET  A       S+T  +     +  + TIT  T+   +  V+++GS 
Sbjct: 151  GSETTTAYTADSETTAA-------STTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSE 203

Query: 877  STLVSSVNADLPIAT---ASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGST-IA 932
            +T VS+  ++   A+   +    A+ +   T+K+  A  G+ T +    S+ T  ST  +
Sbjct: 204  TTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA--GSETTVSTAGSETTAASTEDS 261

Query: 933  EIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQA 992
            E      E  K         +      E T A    S       + + +  +  +     
Sbjct: 262  ETNTAFTEDSK-------TTTASTTGFETTAA----STTGSEPTMASTMGSETTMASTIG 310

Query: 993  VDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSAT--APQQEADAE 1050
             + TK     A+ +   +F     T        +        S T +A+    +   D+ 
Sbjct: 311  PETTKVS--TASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDST 368

Query: 1051 VNTETLNKSSQGS---SSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRET--PS 1105
              +ET   S++GS   ++ST+ + + T S +  + T+   +    +T    GS  T   +
Sbjct: 369  TGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVST 428

Query: 1106 SILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTST 1145
            ++   +   ++ S    +S S S+    ST     T+ +T
Sbjct: 429  TVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTT 468



 Score = 35.8 bits (81), Expect = 0.24
 Identities = 91/473 (19%), Positives = 169/473 (35%), Gaps = 24/473 (5%)

Query: 432  SKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDK 491
            S+   +  TG   + +    S  +  S + + + +      + T    ++S+ +  F + 
Sbjct: 750  SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 809

Query: 492  STASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGS-ILNLNLDRSKAEMDLK 550
            S  + AST   +  ++S +     P  +A   T T  TST GS     + + S+      
Sbjct: 810  SETTIASTTASETTTVSTAGSETIPASTAGSETTTT-TSTEGSETTTASTEGSETTTAST 868

Query: 551  ELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSE 610
            E SE+    +T   + S      +        + E  +      E SE   T V  + SE
Sbjct: 869  ESSET----TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSE--ITTVSTTGSE 922

Query: 611  DSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS----AVKKKPKPTNPVEIKE 666
             +  S +  SE  +   + S+     T   E   +  E S          + T       
Sbjct: 923  TTTAS-TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGS 981

Query: 667  ELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLD 726
            E  + S A  +    +++   +       SE    S    +  +   + +++ TV     
Sbjct: 982  ETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTV---TT 1038

Query: 727  SDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPP--STTVGSHSPPETPVLT 784
            + SE+  V   G + +      ++      +  +     T    +TTV +     T   T
Sbjct: 1039 AGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098

Query: 785  RSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTV 844
              S  T+     + T+T+ST    A   + T S          + T   V   V  ++TV
Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT--TVFTTVSETTTV 1156

Query: 845  QQ--KEITQSPSTSTITLVTSTQSSPLVTSS--GSMSTLVSSVNADLPIATAS 893
                 E T S +  +    TST+ S   T+S  GS +T  S+  ++   A+ +
Sbjct: 1157 STIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTA 1209



 Score = 34.7 bits (78), Expect = 0.54
 Identities = 31/153 (20%), Positives = 67/153 (43%), Gaps = 5/153 (3%)

Query: 769  STTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPK 828
            +TT  +     T   T  S  T+A+ A + T+T+ST        + +GS          +
Sbjct: 1173 ATTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSE 1232

Query: 829  ETAPAVQRVVWNSSTVQQKEITQSPSTS---TITLVTSTQSSPLVTSSGSMSTLVSSVNA 885
             + P+      N++ +   E T + + S   T T +T ++++ +  ++   +   ++V++
Sbjct: 1233 TSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTTVSS 1292

Query: 886  DLPIATASADVAADIAKYTSKMMDAIKGTMTEI 918
               + T + DV+  I   T+  M   + T T +
Sbjct: 1293 TTFVLTKATDVS--IQPITNTPMSGTRTTGTRL 1323



 Score = 32.7 bits (73), Expect = 2.1
 Identities = 37/166 (22%), Positives = 65/166 (39%), Gaps = 23/166 (13%)

Query: 769  STTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPK 828
            +TTV + S   T   T  S  T+     + T+T ST+   A   +A GS           
Sbjct: 1123 ATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEA--------- 1173

Query: 829  ETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSS--GSMSTLVSSVNAD 886
                        +++ +  E T + +  + T   ST  S   T+S  GS +T  S+  ++
Sbjct: 1174 -----------TTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSE 1222

Query: 887  LPIATASADVAADIAKYTSKMMDA-IKGTMTEIYNDLSKNTTGSTI 931
               A  +    +  +   S+   A I G+ T I +  S   T +++
Sbjct: 1223 TNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSL 1268


>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1521

 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 81/406 (19%), Positives = 146/406 (35%), Gaps = 26/406 (6%)

Query: 742  SGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTST 801
            +G E      E  E +       +T   +T GS +   T   T  S  T+ + A +  +T
Sbjct: 549  TGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT---TAASTAGSETTTVSTADSENTT 605

Query: 802  SSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLV 861
            +ST      + + TGS            TA         +ST   +  T S + S  T+V
Sbjct: 606  ASTADSETTSASTTGSETT---------TASTTSSETTTASTEGSETTTVSTTDSETTMV 656

Query: 862  TSTQSSPLVTSS-GSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYN 920
            ++T S   +TS+ GS +T VS+  ++  ++T  +         +     +  G+ T   +
Sbjct: 657  STTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTS 716

Query: 921  DLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAE 980
                  T ++I          E  +            +   T +E   +     +  +A 
Sbjct: 717  TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776

Query: 981  VKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSA 1040
            +    E      +     K   A+ K   +F     T+       +        S   S 
Sbjct: 777  IMGS-ETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASET----TTVSTAGSE 831

Query: 1041 TAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGS 1100
            T P   A +E  T T  + S+ +++ST+ + + TAS    + T+A       +T    GS
Sbjct: 832  TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 891

Query: 1101 RETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTK 1146
              T +S        ++ S +  +S   S+    ST     T+ ST+
Sbjct: 892  ETTTTS--------TEGSETTTASTEGSEITTVSTTGSETTTASTE 929



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 141/739 (19%), Positives = 262/739 (35%), Gaps = 52/739 (7%)

Query: 440  TGRRISLSDMPRSPMSTNSSVHTGSDVEQDA-EKKATSSHFSASEESMDFL----DKSTA 494
            TG   + +    S M+T S+  TG++   D+ E   T++  +A  E+        + +TA
Sbjct: 549  TGLETTTTSTEGSEMTTVST--TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 606

Query: 495  SPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE--L 552
            S A ++T  A S +GS    +   S+  TT + + S T ++   + + +       E  +
Sbjct: 607  STADSETTSA-STTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665

Query: 553  SESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDS 612
            + +   ++T V     +  + +        +I   +        SE   T+ E S+   +
Sbjct: 666  TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTA 725

Query: 613  EKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTS 672
              + S  +   ++  + +    E +E         E +        T    I      T+
Sbjct: 726  SITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS--ETT 783

Query: 673  PASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESE 732
             AS           AS +    F+E ++ +       +     +++ TV     + SE+ 
Sbjct: 784  MASTIGSETTKVSTASSKMTTVFTENSETT-------IASTTASETTTVST---AGSETI 833

Query: 733  LVIDLGEDHS------GREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRS 786
                 G + +      G E      E  E +       +T  +TT+GS +   T   T  
Sbjct: 834  PASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET---TTASTEG 890

Query: 787  SAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQ-RVVWNSSTVQ 845
            S  T+ +   + T+T+ST        + TGS          + T  + +   +   ST  
Sbjct: 891  SETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG 950

Query: 846  QKEITQSPSTSTITLVTSTQSSPLVTSS-GSMSTLVSSVNADLPIATASADVAADIAKYT 904
             + IT S   S  T VT+  S     S+ GS +T VS+  ++   A+        ++   
Sbjct: 951  SETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1010

Query: 905  SKMMD-AIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTM 963
            S+    +  GT T I +     TT  T A      +     +             +  T 
Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070

Query: 964  AEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYP 1023
            +E   +   + +                A  ET             ++     T+     
Sbjct: 1071 SETTTASTADLETTTVSTSGSGTTTASTAGSETT-----------TVYITGSKTTTASTE 1119

Query: 1024 CQQAHWPEHMKSCTQSATAPQQEADAEVNT--ETLNKSSQGSSSSTQSAPSE--TASASK 1079
              +A       S T +A+    E      T  ET   S+ GS ++T SA     T ++++
Sbjct: 1120 GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE 1179

Query: 1080 EKETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTR--- 1136
              ET+   +  S +T   +   ET ++   GS   +  +  +++S  SS     +T    
Sbjct: 1180 GSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFII 1239

Query: 1137 SDHNTSTSTKSLLPKESRL 1155
                T  ST SL P  + L
Sbjct: 1240 GSETTIASTASLEPTATSL 1258



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 77/402 (19%), Positives = 151/402 (37%), Gaps = 45/402 (11%)

Query: 765  KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRP 824
            +T  ++T GS +   +P  ++++  + +     TTST+ +   T  +  +  +       
Sbjct: 34   ETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGS 93

Query: 825  LLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVN 884
                 TA +    V  S T  +  +  +  + T T  T++  + + +++GS +T VS+V 
Sbjct: 94   ETTVSTAGSETTTV--SITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVG 151

Query: 885  ADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKL 944
            ++   A  +AD     A  T          MT ++   S+  T ST         E   +
Sbjct: 152  SETTTA-YTADSETTAASTTG-------SEMTTVFTAGSETITPSTAGS------ETTTV 197

Query: 945  QWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCAN 1004
                 +  +      E T A    S       + +E  K      +  V     +   A+
Sbjct: 198  STAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAAS 257

Query: 1005 CKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSS 1064
             +         NT++           E  K+ T S T  +  A +   +E    S+ GS 
Sbjct: 258  TEDSET-----NTAF----------TEDSKTTTASTTGFETTAASTTGSEPTMASTMGSE 302

Query: 1065 S-------------STQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGS 1111
            +             ST S+   T  A+  +   A       +T+  +GS  T +SI +GS
Sbjct: 303  TTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASI-MGS 361

Query: 1112 NQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKES 1153
               +D +  ++++ +S++    +T S   +  +T S    E+
Sbjct: 362  ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSET 403



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 111/555 (20%), Positives = 187/555 (33%), Gaps = 60/555 (10%)

Query: 400  DPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLS--GGTGRRISLSDMPRSPMSTN 457
            D  N +A TA  +         + T +          S  G     +S +D   + +ST 
Sbjct: 600  DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659

Query: 458  SSVHTGSDVE--QDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFS 515
             S  T +  E  +     AT S  + S E       S     +TK    GS + +     
Sbjct: 660  GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEG 719

Query: 516  PQLSAPITTKTDKTS--------TTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLIS 567
             +++    T ++ T+        TT S        +         + +   ++T   ++ 
Sbjct: 720  SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 779

Query: 568  PKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDE 627
             +  + S   +  + T  S  +       +E+  T +  + + ++    ++ SE I    
Sbjct: 780  SETTMAST--IGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAST 837

Query: 628  QKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKA 687
              S  E   T   EG +     ++ +     T   E  E   +T+  SE          A
Sbjct: 838  AGS--ETTTTTSTEGSETTT--ASTEGSETTTASTESSETTTATTIGSETTT-------A 886

Query: 688  SPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHS--GRE 745
            S E  +  +   +           G + T + T        SE   V   G + +    E
Sbjct: 887  STEGSETTTTSTE-----------GSETTTAST------EGSEITTVSTTGSETTTASTE 929

Query: 746  GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGA---TATTSTS 802
            G +      E S    V      + TV +     T V T  S  T+A+ A   T T ST+
Sbjct: 930  GSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTA 989

Query: 803  STVTVTAPAP-------AATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPST 855
             + T TA          ++TGS          + T  + +     + T    E T   +T
Sbjct: 990  GSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTT 1049

Query: 856  STITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTM 915
             + T  TST+ S   T S + S   ++  ADL   T S   +      T+          
Sbjct: 1050 GSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTA------GSET 1103

Query: 916  TEIYNDLSKNTTGST 930
            T +Y   SK TT ST
Sbjct: 1104 TTVYITGSKTTTAST 1118



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 133/752 (17%), Positives = 263/752 (34%), Gaps = 87/752 (11%)

Query: 434  PVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKST 493
            P  +G     +S +    + +ST  S  T +     A  + T++    SE +     K +
Sbjct: 187  PSTAGSETTTVSTAGSETTTVSTTGSETTTAST---AHSETTAASTMGSETT-----KVS 238

Query: 494  ASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELS 553
             + + T    AGS + +      + +   T   D  +TT S        +        ++
Sbjct: 239  TAGSETTVSTAGSETTAASTEDSETNTAFTE--DSKTTTASTTGFETTAASTTGSEPTMA 296

Query: 554  ESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSE 613
             ++  ++T    I P+    S     +     +    +  + +  +  T V  + SE + 
Sbjct: 297  STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET-TTVSTTGSETTT 355

Query: 614  KSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS---AVKKKPKPTNPVEIKEELKS 670
             S    SE  +D    S+     TE  E      E S    V      T  V I +  ++
Sbjct: 356  ASIMG-SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS-ET 413

Query: 671  TSPASEKADPGAVKDKA--SPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSD 728
            T+  +E ++  AV      +     + SE    S    +      + +++ TV     + 
Sbjct: 414  TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTV---TTAG 470

Query: 729  SESELVIDLGED-----HSGRE-------GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHS 776
            SE++     G +     ++G E       G        E S    V       TTV +  
Sbjct: 471  SETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530

Query: 777  PPETPVLTRSSAQTSAAGATATTSTSST----VTVTAPAPAATGSPVKKQRPLLPKETAP 832
               T V T  S  T+ +     T+T+ST    +T  +   A T +   +        TA 
Sbjct: 531  SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAG 590

Query: 833  AVQRVVWNS------STVQQKEITQSPSTSTITLVTSTQSSPLVTSS--GSMSTLVSSVN 884
            +    V  +      ++    E T + +T + T   ST SS   T+S  GS +T VS+ +
Sbjct: 591  SETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTD 650

Query: 885  ADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKL 944
            ++  + + +       +   S+       T++   ++ + +T GS    +     E  K+
Sbjct: 651  SETTMVSTTGSERTITSTEGSETT-----TVSATGSETTVSTEGSGTTTVSITGSETTKV 705

Query: 945  QWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCAN 1004
                 +  +      E+T A +  S     +   A  +            ET       +
Sbjct: 706  STTGSETTTTSTEGSEITTASITGS-----ETTTASTEGSETTTASTEGSETTSASTTGS 760

Query: 1005 CKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSS 1064
                                         ++ T S T+ +    + + +ET   S+ GS 
Sbjct: 761  -----------------------------ETTTASTTSSETTMASIMGSETTMASTIGSE 791

Query: 1065 S---STQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSN 1121
            +   ST S+   T      + T A  +    +T+  +GS   P+S        +  +  +
Sbjct: 792  TTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGS 851

Query: 1122 KSSWSSSDEKRGSTRSDHNTSTSTKSLLPKES 1153
            +++ +S++    +T S  ++ T+T + +  E+
Sbjct: 852  ETTTASTEGSETTTASTESSETTTATTIGSET 883



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 82/400 (20%), Positives = 156/400 (39%), Gaps = 39/400 (9%)

Query: 760  QDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPV 819
            +  V      TT  S +  ET +++   ++T+     +TTS+ +TVT TA +   T S V
Sbjct: 94   ETTVSTAGSETTTVSITGTETTMVSAMGSETTT---NSTTSSETTVTSTAGSETTTVSTV 150

Query: 820  KKQRP---LLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSM 876
              +         ET  A       S+T  +     +  + TIT  T+   +  V+++GS 
Sbjct: 151  GSETTTAYTADSETTAA-------STTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSE 203

Query: 877  STLVSSVNADLPIAT---ASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGST-IA 932
            +T VS+  ++   A+   +    A+ +   T+K+  A  G+ T +    S+ T  ST  +
Sbjct: 204  TTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA--GSETTVSTAGSETTAASTEDS 261

Query: 933  EIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQA 992
            E      E  K         +      E T A    S       + + +  +  +     
Sbjct: 262  ETNTAFTEDSK-------TTTASTTGFETTAA----STTGSEPTMASTMGSETTMASTIG 310

Query: 993  VDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSAT--APQQEADAE 1050
             + TK     A+ +   +F     T        +        S T +A+    +   D+ 
Sbjct: 311  PETTKVS--TASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDST 368

Query: 1051 VNTETLNKSSQGS---SSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRET--PS 1105
              +ET   S++GS   ++ST+ + + T S +  + T+   +    +T    GS  T   +
Sbjct: 369  TGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVST 428

Query: 1106 SILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTST 1145
            ++   +   ++ S    +S S S+    ST     T+ +T
Sbjct: 429  TVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTT 468



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 92/473 (19%), Positives = 169/473 (35%), Gaps = 24/473 (5%)

Query: 432  SKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDK 491
            S+   +  TG   + +    S  +  S + + + +      + T    ++S+ +  F + 
Sbjct: 750  SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 809

Query: 492  STASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGS-ILNLNLDRSKAEMDLK 550
            S  + AST   +  ++S +     P  +A   T T  TST GS     + + S+      
Sbjct: 810  SETTIASTTASETTTVSTAGSETIPASTAGSETTTT-TSTEGSETTTASTEGSETTTAST 868

Query: 551  ELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSE 610
            E SE+    +T   + S      +        + E  +      E SE   T V  + SE
Sbjct: 869  ESSET----TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSE--ITTVSTTGSE 922

Query: 611  DSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS----AVKKKPKPTNPVEIKE 666
             +  S +  SE  +   + S+     T   E   +  E S          + T       
Sbjct: 923  TTTAS-TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGS 981

Query: 667  ELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLD 726
            E  + S A  +    +++   +       SE    S    +  +   + +++ TV     
Sbjct: 982  ETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTV---TT 1038

Query: 727  SDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPP--STTVGSHSPPETPVLT 784
            + SE+  V   G + +      ++      +  +     T    +TTV +     T   T
Sbjct: 1039 AGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098

Query: 785  RSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTV 844
              S  T+     + T+T+ST    A   + T S          + T   V   V  ++TV
Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT--TVFTTVSETTTV 1156

Query: 845  QQ--KEITQSPSTSTITLVTSTQSSPLVTSS--GSMSTLVSSVNADLPIATAS 893
                 E T S +  +    TST+ S   T+S  GS +T  S+  ++   A+ S
Sbjct: 1157 STIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS 1209



 Score = 33.9 bits (76), Expect = 0.92
 Identities = 34/166 (20%), Positives = 72/166 (43%), Gaps = 12/166 (7%)

Query: 763  VGKTPPSTTVGSHSPPE-------TPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAAT 815
            V +T   +T+GS +          T   T  S  T+A+ A + T+T+ST        + +
Sbjct: 1150 VSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS 1209

Query: 816  GSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTS---TITLVTSTQSSPLVTS 872
            GS          + + P+      N++ +   E T + + S   T T +T ++++ +  +
Sbjct: 1210 GSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSIT 1269

Query: 873  SGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEI 918
            +   +   ++V++   + T + DV+  I   T+  M   + T T +
Sbjct: 1270 ASGATAASTTVSSTTFVLTKATDVS--IQPITNTPMSGTRTTGTRL 1313



 Score = 33.9 bits (76), Expect = 0.92
 Identities = 49/229 (21%), Positives = 82/229 (35%), Gaps = 37/229 (16%)

Query: 729  SESELVIDLGEDHS-----GREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSH-------- 775
            SE+  V  +G + +     G E      E  E +       +T  ++T GS         
Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210

Query: 776  SPPETPVLTRSSAQTSAAGATAT---------TSTSSTVTVTAPAPAATGS-----PVKK 821
            S   T   T S   T ++  + T         T+ +ST ++   A + TGS      +  
Sbjct: 1211 SETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITA 1270

Query: 822  QRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVS 881
                    T  +   V+  ++ V  + IT +P + T T  T   +S  VT +  M    S
Sbjct: 1271 SGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTAS 1330

Query: 882  SVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGST 930
            + +  +P           I   TS +  +  G  +       + TTGST
Sbjct: 1331 AASHTVP----------GIVLNTSGLGTSTMGASSTTSAHGVRTTTGST 1369


>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 81/406 (19%), Positives = 146/406 (35%), Gaps = 26/406 (6%)

Query: 742  SGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTST 801
            +G E      E  E +       +T   +T GS +   T   T  S  T+ + A +  +T
Sbjct: 549  TGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT---TAASTAGSETTTVSTADSENTT 605

Query: 802  SSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLV 861
            +ST      + + TGS            TA         +ST   +  T S + S  T+V
Sbjct: 606  ASTADSETTSASTTGSETT---------TASTTSSETTTASTEGSETTTVSTTDSETTMV 656

Query: 862  TSTQSSPLVTSS-GSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYN 920
            ++T S   +TS+ GS +T VS+  ++  ++T  +         +     +  G+ T   +
Sbjct: 657  STTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTS 716

Query: 921  DLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAE 980
                  T ++I          E  +            +   T +E   +     +  +A 
Sbjct: 717  TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776

Query: 981  VKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSA 1040
            +    E      +     K   A+ K   +F     T+       +        S   S 
Sbjct: 777  IMGS-ETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASET----TTVSTAGSE 831

Query: 1041 TAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGS 1100
            T P   A +E  T T  + S+ +++ST+ + + TAS    + T+A       +T    GS
Sbjct: 832  TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 891

Query: 1101 RETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTK 1146
              T +S        ++ S +  +S   S+    ST     T+ ST+
Sbjct: 892  ETTTTS--------TEGSETTTASTEGSEITTVSTTGSETTTASTE 929



 Score = 53.9 bits (128), Expect = 9e-07
 Identities = 141/739 (19%), Positives = 263/739 (35%), Gaps = 52/739 (7%)

Query: 440  TGRRISLSDMPRSPMSTNSSVHTGSDVEQDA-EKKATSSHFSASEESMDFL----DKSTA 494
            TG   + +    S M+T S+  TG++   D+ E   T++  +A  E+        + +TA
Sbjct: 549  TGLETTTTSTEGSEMTTVST--TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 606

Query: 495  SPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE--L 552
            S A ++T  A S +GS    +   S+  TT + + S T ++   + + +       E  +
Sbjct: 607  STADSETTSA-STTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665

Query: 553  SESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDS 612
            + +   ++T V     +  + +        +I   +        SE   T+ E S+   +
Sbjct: 666  TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTA 725

Query: 613  EKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTS 672
              + S  +   ++  + +    E +E         E +        T    I      T+
Sbjct: 726  SITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS--ETT 783

Query: 673  PASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESE 732
             AS           AS +    F+E ++ +       +     +++ TV     + SE+ 
Sbjct: 784  MASTIGSETTKVSTASSKMTTVFTENSETT-------IASTTASETTTVST---AGSETI 833

Query: 733  LVIDLGEDHS------GREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRS 786
                 G + +      G E      E  E +       +T  +TT+GS +   T   T  
Sbjct: 834  PASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET---TTASTEG 890

Query: 787  SAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQ-RVVWNSSTVQ 845
            S  T+ +   + T+T+ST        + TGS          + T  + +   +   ST  
Sbjct: 891  SETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG 950

Query: 846  QKEITQSPSTSTITLVTSTQSSPLVTSS-GSMSTLVSSVNADLPIATASADVAADIAKYT 904
             + IT S   S  T VT+  S     S+ GS +T VS+  ++   A+        ++   
Sbjct: 951  SETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1010

Query: 905  SKMMD-AIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTM 963
            S+    +  GT T I +     TT  T A      +     +             +  T 
Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070

Query: 964  AEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYP 1023
            +E   +   + +                A  ET             ++     T+     
Sbjct: 1071 SETTTASTADLETTTVSTSGSGTTTASTAGSETT-----------TVYITGSKTTTASTE 1119

Query: 1024 CQQAHWPEHMKSCTQSATAPQQEADAEVNT--ETLNKSSQGSSSSTQSAPSE--TASASK 1079
              +A       S T +A+    E      T  ET   S+ GS ++T SA     T ++++
Sbjct: 1120 GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE 1179

Query: 1080 EKETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTR--- 1136
              ET+   +  S +T   +   ET ++   GS   +  +  +++S  SS     +T    
Sbjct: 1180 GSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFII 1239

Query: 1137 SDHNTSTSTKSLLPKESRL 1155
               +T  ST SL P  + L
Sbjct: 1240 GSESTIASTASLEPTATSL 1258



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 77/402 (19%), Positives = 151/402 (37%), Gaps = 45/402 (11%)

Query: 765  KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRP 824
            +T  ++T GS +   +P  ++++  + +     TTST+ +   T  +  +  +       
Sbjct: 34   ETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGS 93

Query: 825  LLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVN 884
                 TA +    V  S T  +  +  +  + T T  T++  + + +++GS +T VS+V 
Sbjct: 94   ETTVSTAGSETTTV--SITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVG 151

Query: 885  ADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKL 944
            ++   A  +AD     A  T          MT ++   S+  T ST         E   +
Sbjct: 152  SETTTA-YTADSETTAASTTG-------SEMTTVFTAGSETITPSTAGS------ETTTV 197

Query: 945  QWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCAN 1004
                 +  +      E T A    S       + +E  K      +  V     +   A+
Sbjct: 198  STAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAAS 257

Query: 1005 CKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSS 1064
             +         NT++           E  K+ T S T  +  A +   +E    S+ GS 
Sbjct: 258  TEDSET-----NTAF----------TEDSKTTTASTTGFETTAASTTGSEPTMASTMGSE 302

Query: 1065 S-------------STQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGS 1111
            +             ST S+   T  A+  +   A       +T+  +GS  T +SI +GS
Sbjct: 303  TTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASI-MGS 361

Query: 1112 NQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKES 1153
               +D +  ++++ +S++    +T S   +  +T S    E+
Sbjct: 362  ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSET 403



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 111/555 (20%), Positives = 187/555 (33%), Gaps = 60/555 (10%)

Query: 400  DPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLS--GGTGRRISLSDMPRSPMSTN 457
            D  N +A TA  +         + T +          S  G     +S +D   + +ST 
Sbjct: 600  DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659

Query: 458  SSVHTGSDVE--QDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFS 515
             S  T +  E  +     AT S  + S E       S     +TK    GS + +     
Sbjct: 660  GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEG 719

Query: 516  PQLSAPITTKTDKTS--------TTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLIS 567
             +++    T ++ T+        TT S        +         + +   ++T   ++ 
Sbjct: 720  SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 779

Query: 568  PKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDE 627
             +  + S   +  + T  S  +       +E+  T +  + + ++    ++ SE I    
Sbjct: 780  SETTMAST--IGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAST 837

Query: 628  QKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKA 687
              S  E   T   EG +     ++ +     T   E  E   +T+  SE          A
Sbjct: 838  AGS--ETTTTTSTEGSETTT--ASTEGSETTTASTESSETTTATTIGSETTT-------A 886

Query: 688  SPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHS--GRE 745
            S E  +  +   +           G + T + T        SE   V   G + +    E
Sbjct: 887  STEGSETTTTSTE-----------GSETTTAST------EGSEITTVSTTGSETTTASTE 929

Query: 746  GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGA---TATTSTS 802
            G +      E S    V      + TV +     T V T  S  T+A+ A   T T ST+
Sbjct: 930  GSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTA 989

Query: 803  STVTVTAPAP-------AATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPST 855
             + T TA          ++TGS          + T  + +     + T    E T   +T
Sbjct: 990  GSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTT 1049

Query: 856  STITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTM 915
             + T  TST+ S   T S + S   ++  ADL   T S   +      T+          
Sbjct: 1050 GSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTA------GSET 1103

Query: 916  TEIYNDLSKNTTGST 930
            T +Y   SK TT ST
Sbjct: 1104 TTVYITGSKTTTAST 1118



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 133/752 (17%), Positives = 263/752 (34%), Gaps = 87/752 (11%)

Query: 434  PVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKST 493
            P  +G     +S +    + +ST  S  T +     A  + T++    SE +     K +
Sbjct: 187  PSTAGSETTTVSTAGSETTTVSTTGSETTTAST---AHSETTAASTMGSETT-----KVS 238

Query: 494  ASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELS 553
             + + T    AGS + +      + +   T   D  +TT S        +        ++
Sbjct: 239  TAGSETTVSTAGSETTAASTEDSETNTAFTE--DSKTTTASTTGFETTAASTTGSEPTMA 296

Query: 554  ESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSE 613
             ++  ++T    I P+    S     +     +    +  + +  +  T V  + SE + 
Sbjct: 297  STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET-TTVSTTGSETTT 355

Query: 614  KSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS---AVKKKPKPTNPVEIKEELKS 670
             S    SE  +D    S+     TE  E      E S    V      T  V I +  ++
Sbjct: 356  ASIMG-SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS-ET 413

Query: 671  TSPASEKADPGAVKDKA--SPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSD 728
            T+  +E ++  AV      +     + SE    S    +      + +++ TV     + 
Sbjct: 414  TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTV---TTAG 470

Query: 729  SESELVIDLGED-----HSGRE-------GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHS 776
            SE++     G +     ++G E       G        E S    V       TTV +  
Sbjct: 471  SETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530

Query: 777  PPETPVLTRSSAQTSAAGATATTSTSST----VTVTAPAPAATGSPVKKQRPLLPKETAP 832
               T V T  S  T+ +     T+T+ST    +T  +   A T +   +        TA 
Sbjct: 531  SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAG 590

Query: 833  AVQRVVWNS------STVQQKEITQSPSTSTITLVTSTQSSPLVTSS--GSMSTLVSSVN 884
            +    V  +      ++    E T + +T + T   ST SS   T+S  GS +T VS+ +
Sbjct: 591  SETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTD 650

Query: 885  ADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKL 944
            ++  + + +       +   S+       T++   ++ + +T GS    +     E  K+
Sbjct: 651  SETTMVSTTGSERTITSTEGSETT-----TVSATGSETTVSTEGSGTTTVSITGSETTKV 705

Query: 945  QWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCAN 1004
                 +  +      E+T A +  S     +   A  +            ET       +
Sbjct: 706  STTGSETTTTSTEGSEITTASITGS-----ETTTASTEGSETTTASTEGSETTSASTTGS 760

Query: 1005 CKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSS 1064
                                         ++ T S T+ +    + + +ET   S+ GS 
Sbjct: 761  -----------------------------ETTTASTTSSETTMASIMGSETTMASTIGSE 791

Query: 1065 S---STQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSN 1121
            +   ST S+   T      + T A  +    +T+  +GS   P+S        +  +  +
Sbjct: 792  TTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGS 851

Query: 1122 KSSWSSSDEKRGSTRSDHNTSTSTKSLLPKES 1153
            +++ +S++    +T S  ++ T+T + +  E+
Sbjct: 852  ETTTASTEGSETTTASTESSETTTATTIGSET 883



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 82/400 (20%), Positives = 156/400 (39%), Gaps = 39/400 (9%)

Query: 760  QDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPV 819
            +  V      TT  S +  ET +++   ++T+     +TTS+ +TVT TA +   T S V
Sbjct: 94   ETTVSTAGSETTTVSITGTETTMVSAMGSETTT---NSTTSSETTVTSTAGSETTTVSTV 150

Query: 820  KKQRP---LLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSM 876
              +         ET  A       S+T  +     +  + TIT  T+   +  V+++GS 
Sbjct: 151  GSETTTAYTADSETTAA-------STTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSE 203

Query: 877  STLVSSVNADLPIAT---ASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGST-IA 932
            +T VS+  ++   A+   +    A+ +   T+K+  A  G+ T +    S+ T  ST  +
Sbjct: 204  TTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA--GSETTVSTAGSETTAASTEDS 261

Query: 933  EIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQA 992
            E      E  K         +      E T A    S       + + +  +  +     
Sbjct: 262  ETNTAFTEDSK-------TTTASTTGFETTAA----STTGSEPTMASTMGSETTMASTIG 310

Query: 993  VDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSAT--APQQEADAE 1050
             + TK     A+ +   +F     T        +        S T +A+    +   D+ 
Sbjct: 311  PETTKVS--TASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDST 368

Query: 1051 VNTETLNKSSQGS---SSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRET--PS 1105
              +ET   S++GS   ++ST+ + + T S +  + T+   +    +T    GS  T   +
Sbjct: 369  TGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVST 428

Query: 1106 SILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTST 1145
            ++   +   ++ S    +S S S+    ST     T+ +T
Sbjct: 429  TVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTT 468



 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 134/724 (18%), Positives = 240/724 (33%), Gaps = 56/724 (7%)

Query: 437  SGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASP 496
            +G     +S +D   +  ST  S  T +         A+++    +  S +  + +T S 
Sbjct: 589  AGSETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVST 648

Query: 497  ASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELSESV 556
              ++T    S +GS +  +    +  TT     S TGS   ++ + S         SE+ 
Sbjct: 649  TDSETTMV-STTGSERTITSTEGSETTT----VSATGSETTVSTEGSGTTTVSITGSETT 703

Query: 557  QQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSD 616
            +  +T     S      +        +I   +      E SE    + E S++  +  + 
Sbjct: 704  KVSTTG----SETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTG 759

Query: 617  SSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPV--EIKEELKSTSPA 674
            S  +   +   + +      +E      +  E + V         V  E  E   +++ A
Sbjct: 760  SETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTA 819

Query: 675  SEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELV 734
            SE         +  P      SE    +     +      E    T      S++ +   
Sbjct: 820  SETTTVSTAGSETIPASTAG-SETTTTTSTEGSETTTASTEGSETTTASTESSETTTATT 878

Query: 735  IDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAG 794
            I      +  EG +      E S       +    TTV +     T   T  S  T+A+ 
Sbjct: 879  IGSETTTASTEGSETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTAST 938

Query: 795  -----ATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEI 849
                  T +T+ S T+TV+A     T              TA          ST   +  
Sbjct: 939  EGSELTTVSTTGSETITVSAEGSETTTVTTMGSETT----TASTAGSETTTVSTAGSETT 994

Query: 850  TQSPSTSTITLVTSTQS-SPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMM 908
            T S   S  T V+ST S +  V+++G+ +T+ S+  ++    T +       A YT+   
Sbjct: 995  TASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETT--AVYTTGSE 1052

Query: 909  DAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQ 968
                 T TE     + +TTGS         +E   +        +      E T   +  
Sbjct: 1053 TTT--TSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITG 1110

Query: 969  SLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAH 1028
            S                E  +   V  T  +   A+     +       S          
Sbjct: 1111 S---------KTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTTVS---------- 1151

Query: 1029 WPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQS-APSETASAS---KEKETS 1084
                 ++ T S    +    +   +E    S++GS ++T S A SET +AS    E  T+
Sbjct: 1152 -----ETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTA 1206

Query: 1085 AEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTS 1144
            +    E+ +         TPSS   GS   +     ++S+ +S+     +  S   + T+
Sbjct: 1207 STSGSETNTACTTGSETSTPSS--AGSETNTAFIIGSESTIASTASLEPTATSLTGSETT 1264

Query: 1145 TKSL 1148
            T S+
Sbjct: 1265 TVSI 1268



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 92/473 (19%), Positives = 169/473 (35%), Gaps = 24/473 (5%)

Query: 432  SKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDK 491
            S+   +  TG   + +    S  +  S + + + +      + T    ++S+ +  F + 
Sbjct: 750  SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 809

Query: 492  STASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGS-ILNLNLDRSKAEMDLK 550
            S  + AST   +  ++S +     P  +A   T T  TST GS     + + S+      
Sbjct: 810  SETTIASTTASETTTVSTAGSETIPASTAGSETTTT-TSTEGSETTTASTEGSETTTAST 868

Query: 551  ELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSE 610
            E SE+    +T   + S      +        + E  +      E SE   T V  + SE
Sbjct: 869  ESSET----TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSE--ITTVSTTGSE 922

Query: 611  DSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS----AVKKKPKPTNPVEIKE 666
             +  S +  SE  +   + S+     T   E   +  E S          + T       
Sbjct: 923  TTTAS-TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGS 981

Query: 667  ELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLD 726
            E  + S A  +    +++   +       SE    S    +  +   + +++ TV     
Sbjct: 982  ETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTV---TT 1038

Query: 727  SDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPP--STTVGSHSPPETPVLT 784
            + SE+  V   G + +      ++      +  +     T    +TTV +     T   T
Sbjct: 1039 AGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098

Query: 785  RSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTV 844
              S  T+     + T+T+ST    A   + T S          + T   V   V  ++TV
Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT--TVFTTVSETTTV 1156

Query: 845  QQ--KEITQSPSTSTITLVTSTQSSPLVTSS--GSMSTLVSSVNADLPIATAS 893
                 E T S +  +    TST+ S   T+S  GS +T  S+  ++   A+ S
Sbjct: 1157 STIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS 1209



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 34/166 (20%), Positives = 72/166 (43%), Gaps = 12/166 (7%)

Query: 763  VGKTPPSTTVGSHSPPE-------TPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAAT 815
            V +T   +T+GS +          T   T  S  T+A+ A + T+T+ST        + +
Sbjct: 1150 VSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS 1209

Query: 816  GSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTS---TITLVTSTQSSPLVTS 872
            GS          + + P+      N++ +   E T + + S   T T +T ++++ +  +
Sbjct: 1210 GSETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSIT 1269

Query: 873  SGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEI 918
            +   +   ++V++   + T + DV+  I   T+  M   + T T +
Sbjct: 1270 ASGATAASTTVSSTTFVLTKATDVS--IQPITNTPMSGTRTTGTRL 1313



 Score = 33.1 bits (74), Expect = 1.6
 Identities = 42/170 (24%), Positives = 61/170 (35%), Gaps = 13/170 (7%)

Query: 769  STTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGS-PVKKQRPLLP 827
            +TTV + S   T   T  S  T+     + T+T ST+   A   +A GS           
Sbjct: 1123 ATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSE 1182

Query: 828  KETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSS-----------GSM 876
              TA         +ST   +  T S S S      +T S     SS           GS 
Sbjct: 1183 TTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFIIGSE 1242

Query: 877  STLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNT 926
            ST+ S+ + + P AT+           T+    A   T++     L+K T
Sbjct: 1243 STIASTASLE-PTATSLTGSETTTVSITASGATAASTTVSSTTFVLTKAT 1291



 Score = 33.1 bits (74), Expect = 1.6
 Identities = 51/229 (22%), Positives = 83/229 (36%), Gaps = 37/229 (16%)

Query: 729  SESELVIDLGEDHS-----GREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSH-------- 775
            SE+  V  +G + +     G E      E  E +       +T  ++T GS         
Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210

Query: 776  SPPETPVLTRSSAQT-SAAGATATT--------STSSTVTVTAPAPAATGS-----PVKK 821
            S   T   T S   T S+AG+   T        + +ST ++   A + TGS      +  
Sbjct: 1211 SETNTACTTGSETSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSITA 1270

Query: 822  QRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVS 881
                    T  +   V+  ++ V  + IT +P + T T  T   +S  VT +  M    S
Sbjct: 1271 SGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTAS 1330

Query: 882  SVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGST 930
            + +  +P           I   TS +  +  G  +       + TTGST
Sbjct: 1331 AASHTVP----------GIVLNTSGLGTSTMGASSTTSAHGVRTTTGST 1369


>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1542

 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 81/406 (19%), Positives = 146/406 (35%), Gaps = 26/406 (6%)

Query: 742  SGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTST 801
            +G E      E  E +       +T   +T GS +   T   T  S  T+ + A +  +T
Sbjct: 570  TGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT---TAASTAGSETTTVSTADSENTT 626

Query: 802  SSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLV 861
            +ST      + + TGS            TA         +ST   +  T S + S  T+V
Sbjct: 627  ASTADSETTSASTTGSETT---------TASTTSSETTTASTEGSETTTVSTTDSETTMV 677

Query: 862  TSTQSSPLVTSS-GSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYN 920
            ++T S   +TS+ GS +T VS+  ++  ++T  +         +     +  G+ T   +
Sbjct: 678  STTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTS 737

Query: 921  DLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAE 980
                  T ++I          E  +            +   T +E   +     +  +A 
Sbjct: 738  TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 797

Query: 981  VKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSA 1040
            +    E      +     K   A+ K   +F     T+       +        S   S 
Sbjct: 798  IMGS-ETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASET----TTVSTAGSE 852

Query: 1041 TAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGS 1100
            T P   A +E  T T  + S+ +++ST+ + + TAS    + T+A       +T    GS
Sbjct: 853  TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 912

Query: 1101 RETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTK 1146
              T +S        ++ S +  +S   S+    ST     T+ ST+
Sbjct: 913  ETTTTS--------TEGSETTTASTEGSEITTVSTTGSETTTASTE 950



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 141/739 (19%), Positives = 262/739 (35%), Gaps = 52/739 (7%)

Query: 440  TGRRISLSDMPRSPMSTNSSVHTGSDVEQDA-EKKATSSHFSASEESMDFL----DKSTA 494
            TG   + +    S M+T S+  TG++   D+ E   T++  +A  E+        + +TA
Sbjct: 570  TGLETTTTSTEGSEMTTVST--TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 627

Query: 495  SPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE--L 552
            S A ++T  A S +GS    +   S+  TT + + S T ++   + + +       E  +
Sbjct: 628  STADSETTSA-STTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 686

Query: 553  SESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDS 612
            + +   ++T V     +  + +        +I   +        SE   T+ E S+   +
Sbjct: 687  TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTA 746

Query: 613  EKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTS 672
              + S  +   ++  + +    E +E         E +        T    I      T+
Sbjct: 747  SITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS--ETT 804

Query: 673  PASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESE 732
             AS           AS +    F+E ++ +       +     +++ TV     + SE+ 
Sbjct: 805  MASTIGSETTKVSTASSKMTTVFTENSETT-------IASTTASETTTVST---AGSETI 854

Query: 733  LVIDLGEDHS------GREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRS 786
                 G + +      G E      E  E +       +T  +TT+GS +   T   T  
Sbjct: 855  PASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET---TTASTEG 911

Query: 787  SAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQ-RVVWNSSTVQ 845
            S  T+ +   + T+T+ST        + TGS          + T  + +   +   ST  
Sbjct: 912  SETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG 971

Query: 846  QKEITQSPSTSTITLVTSTQSSPLVTSS-GSMSTLVSSVNADLPIATASADVAADIAKYT 904
             + IT S   S  T VT+  S     S+ GS +T VS+  ++   A+        ++   
Sbjct: 972  SETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1031

Query: 905  SKMMD-AIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTM 963
            S+    +  GT T I +     TT  T A      +     +             +  T 
Sbjct: 1032 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1091

Query: 964  AEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYP 1023
            +E   +   + +                A  ET             ++     T+     
Sbjct: 1092 SETTTASTADLETTTVSTSGSGTTTASTAGSETT-----------TVYITGSKTTTASTE 1140

Query: 1024 CQQAHWPEHMKSCTQSATAPQQEADAEVNT--ETLNKSSQGSSSSTQSAPSE--TASASK 1079
              +A       S T +A+    E      T  ET   S+ GS ++T SA     T ++++
Sbjct: 1141 GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE 1200

Query: 1080 EKETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTR--- 1136
              ET+   +  S +T   +   ET ++   GS   +  +  +++S  SS     +T    
Sbjct: 1201 GSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFII 1260

Query: 1137 SDHNTSTSTKSLLPKESRL 1155
                T  ST SL P  + L
Sbjct: 1261 GSETTIASTASLEPTATSL 1279



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 77/402 (19%), Positives = 151/402 (37%), Gaps = 45/402 (11%)

Query: 765  KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRP 824
            +T  ++T GS +   +P  ++++  + +     TTST+ +   T  +  +  +       
Sbjct: 55   ETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGS 114

Query: 825  LLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVN 884
                 TA +    V  S T  +  +  +  + T T  T++  + + +++GS +T VS+V 
Sbjct: 115  ESTISTAGSETTTV--SITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVG 172

Query: 885  ADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKL 944
            ++   A  +AD     A  T          MT ++   S+  T ST         E   +
Sbjct: 173  SETTTA-YTADSETTAASTTG-------SEMTTVFTAGSETITPSTAGS------ETTTV 218

Query: 945  QWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCAN 1004
                 +  +      E T A    S       + +E  K      +  V     +   A+
Sbjct: 219  STAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAAS 278

Query: 1005 CKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSS 1064
             +         NT++           E  K+ T S T  +  A +   +E    S+ GS 
Sbjct: 279  TEDSET-----NTAF----------TEDSKTTTASTTGFETTAASTTGSEPTMASTMGSE 323

Query: 1065 S-------------STQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGS 1111
            +             ST S+   T  A+  +   A       +T+  +GS  T +SI +GS
Sbjct: 324  TTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASI-MGS 382

Query: 1112 NQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKES 1153
               +D +  ++++ +S++    +T S   +  +T S    E+
Sbjct: 383  ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSET 424



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 111/555 (20%), Positives = 187/555 (33%), Gaps = 60/555 (10%)

Query: 400  DPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLS--GGTGRRISLSDMPRSPMSTN 457
            D  N +A TA  +         + T +          S  G     +S +D   + +ST 
Sbjct: 621  DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 680

Query: 458  SSVHTGSDVE--QDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFS 515
             S  T +  E  +     AT S  + S E       S     +TK    GS + +     
Sbjct: 681  GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEG 740

Query: 516  PQLSAPITTKTDKTS--------TTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLIS 567
             +++    T ++ T+        TT S        +         + +   ++T   ++ 
Sbjct: 741  SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 800

Query: 568  PKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDE 627
             +  + S   +  + T  S  +       +E+  T +  + + ++    ++ SE I    
Sbjct: 801  SETTMAST--IGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAST 858

Query: 628  QKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKA 687
              S  E   T   EG +     ++ +     T   E  E   +T+  SE          A
Sbjct: 859  AGS--ETTTTTSTEGSETTT--ASTEGSETTTASTESSETTTATTIGSETTT-------A 907

Query: 688  SPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHS--GRE 745
            S E  +  +   +           G + T + T        SE   V   G + +    E
Sbjct: 908  STEGSETTTTSTE-----------GSETTTAST------EGSEITTVSTTGSETTTASTE 950

Query: 746  GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGA---TATTSTS 802
            G +      E S    V      + TV +     T V T  S  T+A+ A   T T ST+
Sbjct: 951  GSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTA 1010

Query: 803  STVTVTAPAP-------AATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPST 855
             + T TA          ++TGS          + T  + +     + T    E T   +T
Sbjct: 1011 GSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTT 1070

Query: 856  STITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTM 915
             + T  TST+ S   T S + S   ++  ADL   T S   +      T+          
Sbjct: 1071 GSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTA------GSET 1124

Query: 916  TEIYNDLSKNTTGST 930
            T +Y   SK TT ST
Sbjct: 1125 TTVYITGSKTTTAST 1139



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 133/752 (17%), Positives = 263/752 (34%), Gaps = 87/752 (11%)

Query: 434  PVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKST 493
            P  +G     +S +    + +ST  S  T +     A  + T++    SE +     K +
Sbjct: 208  PSTAGSETTTVSTAGSETTTVSTTGSETTTAST---AHSETTAASTMGSETT-----KVS 259

Query: 494  ASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELS 553
             + + T    AGS + +      + +   T   D  +TT S        +        ++
Sbjct: 260  TAGSETTVSTAGSETTAASTEDSETNTAFTE--DSKTTTASTTGFETTAASTTGSEPTMA 317

Query: 554  ESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSE 613
             ++  ++T    I P+    S     +     +    +  + +  +  T V  + SE + 
Sbjct: 318  STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET-TTVSTTGSETTT 376

Query: 614  KSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS---AVKKKPKPTNPVEIKEELKS 670
             S    SE  +D    S+     TE  E      E S    V      T  V I +  ++
Sbjct: 377  ASIMG-SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS-ET 434

Query: 671  TSPASEKADPGAVKDKA--SPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSD 728
            T+  +E ++  AV      +     + SE    S    +      + +++ TV     + 
Sbjct: 435  TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTV---TTAG 491

Query: 729  SESELVIDLGED-----HSGRE-------GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHS 776
            SE++     G +     ++G E       G        E S    V       TTV +  
Sbjct: 492  SETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 551

Query: 777  PPETPVLTRSSAQTSAAGATATTSTSST----VTVTAPAPAATGSPVKKQRPLLPKETAP 832
               T V T  S  T+ +     T+T+ST    +T  +   A T +   +        TA 
Sbjct: 552  SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAG 611

Query: 833  AVQRVVWNS------STVQQKEITQSPSTSTITLVTSTQSSPLVTSS--GSMSTLVSSVN 884
            +    V  +      ++    E T + +T + T   ST SS   T+S  GS +T VS+ +
Sbjct: 612  SETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTD 671

Query: 885  ADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKL 944
            ++  + + +       +   S+       T++   ++ + +T GS    +     E  K+
Sbjct: 672  SETTMVSTTGSERTITSTEGSETT-----TVSATGSETTVSTEGSGTTTVSITGSETTKV 726

Query: 945  QWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCAN 1004
                 +  +      E+T A +  S     +   A  +            ET       +
Sbjct: 727  STTGSETTTTSTEGSEITTASITGS-----ETTTASTEGSETTTASTEGSETTSASTTGS 781

Query: 1005 CKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSS 1064
                                         ++ T S T+ +    + + +ET   S+ GS 
Sbjct: 782  -----------------------------ETTTASTTSSETTMASIMGSETTMASTIGSE 812

Query: 1065 S---STQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSN 1121
            +   ST S+   T      + T A  +    +T+  +GS   P+S        +  +  +
Sbjct: 813  TTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGS 872

Query: 1122 KSSWSSSDEKRGSTRSDHNTSTSTKSLLPKES 1153
            +++ +S++    +T S  ++ T+T + +  E+
Sbjct: 873  ETTTASTEGSETTTASTESSETTTATTIGSET 904



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 129/727 (17%), Positives = 246/727 (33%), Gaps = 60/727 (8%)

Query: 441  GRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKSTASPASTK 500
            G   + +    S + T SS+ + + V   A    T++  + SE +   +  S  + AST 
Sbjct: 3    GSEATTTSTADSKVITASSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTAST- 61

Query: 501  TGQAGSLSGSPKPFSPQLS------APITTKTDKTSTTGSILNLNLDRSKAEMDLKELSE 554
               AGS + +P P   Q +      + ITT +   S   ++ +     + A M   E + 
Sbjct: 62   ---AGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSESTI 118

Query: 555  SVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEK 614
            S     T    I+           +   T  +  ++  +   +    T V    SE +  
Sbjct: 119  STAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTT- 177

Query: 615  SDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPA 674
            + ++DSE  +     S+     T   E       PS    +    +    +    ST+ +
Sbjct: 178  AYTADSETTAASTTGSEMTTVFTAGSETIT----PSTAGSETTTVSTAGSETTTVSTTGS 233

Query: 675  SEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELV 734
                   A  +  +       + K   +         G + T + T     DS++ +   
Sbjct: 234  ETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAASTE----DSETNTAFT 289

Query: 735  ID---LGEDHSGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTS 791
             D        +G E         EP+    +  +T  ++T+G   P  T V T SS  T+
Sbjct: 290  EDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIG---PETTKVSTASSEVTT 346

Query: 792  AAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQ 851
               A + T  +STV       + TGS       ++  ET+        +S+T  +     
Sbjct: 347  VFAAGSETIRASTVGSETTTVSTTGSET-TTASIMGSETST-------DSTTGSETTTAS 398

Query: 852  SPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASAD----VAADIAKYTSKM 907
            +  + T T  T    +  V+++GS +T VS  +++             V+  + + T+  
Sbjct: 399  TEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVSTTVFETTTAS 458

Query: 908  MDAIKGTM--TEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMA- 964
             +  + T+  T      + +T GS    +     E +       +  +     LE T   
Sbjct: 459  TEGSEITIASTSDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVF 518

Query: 965  -----EMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSY 1019
                     S E      ++    ++     +  + T      +            +T+ 
Sbjct: 519  TIGSDTTTASTEGSETTAVSATGSEMTTVSTEGSENTTVSTTGSETTTV-------STTG 571

Query: 1020 CDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASK 1079
             +         E     T  A       +    T      S+ ++ ST  + + TAS + 
Sbjct: 572  LETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTAD 631

Query: 1080 EKETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDH 1139
             + TSA  +    +T   + S  T +S        ++ S +   S + S+    ST    
Sbjct: 632  SETTSASTTGSETTTASTTSSETTTAS--------TEGSETTTVSTTDSETTMVSTTGSE 683

Query: 1140 NTSTSTK 1146
             T TST+
Sbjct: 684  RTITSTE 690



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 92/473 (19%), Positives = 169/473 (35%), Gaps = 24/473 (5%)

Query: 432  SKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDK 491
            S+   +  TG   + +    S  +  S + + + +      + T    ++S+ +  F + 
Sbjct: 771  SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 830

Query: 492  STASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGS-ILNLNLDRSKAEMDLK 550
            S  + AST   +  ++S +     P  +A   T T  TST GS     + + S+      
Sbjct: 831  SETTIASTTASETTTVSTAGSETIPASTAGSETTTT-TSTEGSETTTASTEGSETTTAST 889

Query: 551  ELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSE 610
            E SE+    +T   + S      +        + E  +      E SE   T V  + SE
Sbjct: 890  ESSET----TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSE--ITTVSTTGSE 943

Query: 611  DSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS----AVKKKPKPTNPVEIKE 666
             +  S +  SE  +   + S+     T   E   +  E S          + T       
Sbjct: 944  TTTAS-TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGS 1002

Query: 667  ELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLD 726
            E  + S A  +    +++   +       SE    S    +  +   + +++ TV     
Sbjct: 1003 ETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTV---TT 1059

Query: 727  SDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPP--STTVGSHSPPETPVLT 784
            + SE+  V   G + +      ++      +  +     T    +TTV +     T   T
Sbjct: 1060 AGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1119

Query: 785  RSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTV 844
              S  T+     + T+T+ST    A   + T S          + T   V   V  ++TV
Sbjct: 1120 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT--TVFTTVSETTTV 1177

Query: 845  QQ--KEITQSPSTSTITLVTSTQSSPLVTSS--GSMSTLVSSVNADLPIATAS 893
                 E T S +  +    TST+ S   T+S  GS +T  S+  ++   A+ S
Sbjct: 1178 STIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS 1230



 Score = 33.9 bits (76), Expect = 0.92
 Identities = 34/166 (20%), Positives = 72/166 (43%), Gaps = 12/166 (7%)

Query: 763  VGKTPPSTTVGSHSPPE-------TPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAAT 815
            V +T   +T+GS +          T   T  S  T+A+ A + T+T+ST        + +
Sbjct: 1171 VSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS 1230

Query: 816  GSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTS---TITLVTSTQSSPLVTS 872
            GS          + + P+      N++ +   E T + + S   T T +T ++++ +  +
Sbjct: 1231 GSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSIT 1290

Query: 873  SGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEI 918
            +   +   ++V++   + T + DV+  I   T+  M   + T T +
Sbjct: 1291 ASGATAASTTVSSTTFVLTKATDVS--IQPITNTPMSGTRTTGTRL 1334



 Score = 33.9 bits (76), Expect = 0.92
 Identities = 49/229 (21%), Positives = 82/229 (35%), Gaps = 37/229 (16%)

Query: 729  SESELVIDLGEDHS-----GREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSH-------- 775
            SE+  V  +G + +     G E      E  E +       +T  ++T GS         
Sbjct: 1172 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1231

Query: 776  SPPETPVLTRSSAQTSAAGATAT---------TSTSSTVTVTAPAPAATGS-----PVKK 821
            S   T   T S   T ++  + T         T+ +ST ++   A + TGS      +  
Sbjct: 1232 SETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITA 1291

Query: 822  QRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVS 881
                    T  +   V+  ++ V  + IT +P + T T  T   +S  VT +  M    S
Sbjct: 1292 SGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRLTASSSVTMAPGMDFTAS 1351

Query: 882  SVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGST 930
            + +  +P           I   TS +  +  G  +       + TTGST
Sbjct: 1352 AASHTVP----------GIVLNTSGLGTSTMGASSTTSAHGVRTTTGST 1390


>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1612

 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 81/406 (19%), Positives = 146/406 (35%), Gaps = 26/406 (6%)

Query: 742  SGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTST 801
            +G E      E  E +       +T   +T GS +   T   T  S  T+ + A +  +T
Sbjct: 549  TGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT---TAASTAGSETTTVSTADSENTT 605

Query: 802  SSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLV 861
            +ST      + + TGS            TA         +ST   +  T S + S  T+V
Sbjct: 606  ASTADSETTSASTTGSETT---------TASTTSSETTTASTEGSETTTVSTTDSETTMV 656

Query: 862  TSTQSSPLVTSS-GSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYN 920
            ++T S   +TS+ GS +T VS+  ++  ++T  +         +     +  G+ T   +
Sbjct: 657  STTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTS 716

Query: 921  DLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAE 980
                  T ++I          E  +            +   T +E   +     +  +A 
Sbjct: 717  TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776

Query: 981  VKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSA 1040
            +    E      +     K   A+ K   +F     T+       +        S   S 
Sbjct: 777  IMGS-ETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASET----TTVSTAGSE 831

Query: 1041 TAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGS 1100
            T P   A +E  T T  + S+ +++ST+ + + TAS    + T+A       +T    GS
Sbjct: 832  TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 891

Query: 1101 RETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTK 1146
              T +S        ++ S +  +S   S+    ST     T+ ST+
Sbjct: 892  ETTTTS--------TEGSETTTASTEGSEITTVSTTGSETTTASTE 929



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 141/739 (19%), Positives = 262/739 (35%), Gaps = 52/739 (7%)

Query: 440  TGRRISLSDMPRSPMSTNSSVHTGSDVEQDA-EKKATSSHFSASEESMDFL----DKSTA 494
            TG   + +    S M+T S+  TG++   D+ E   T++  +A  E+        + +TA
Sbjct: 549  TGLETTTTSTEGSEMTTVST--TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 606

Query: 495  SPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE--L 552
            S A ++T  A S +GS    +   S+  TT + + S T ++   + + +       E  +
Sbjct: 607  STADSETTSA-STTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665

Query: 553  SESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDS 612
            + +   ++T V     +  + +        +I   +        SE   T+ E S+   +
Sbjct: 666  TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTA 725

Query: 613  EKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTS 672
              + S  +   ++  + +    E +E         E +        T    I      T+
Sbjct: 726  SITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS--ETT 783

Query: 673  PASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESE 732
             AS           AS +    F+E ++ +       +     +++ TV     + SE+ 
Sbjct: 784  MASTIGSETTKVSTASSKMTTVFTENSETT-------IASTTASETTTVST---AGSETI 833

Query: 733  LVIDLGEDHS------GREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRS 786
                 G + +      G E      E  E +       +T  +TT+GS +   T   T  
Sbjct: 834  PASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET---TTASTEG 890

Query: 787  SAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQ-RVVWNSSTVQ 845
            S  T+ +   + T+T+ST        + TGS          + T  + +   +   ST  
Sbjct: 891  SETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG 950

Query: 846  QKEITQSPSTSTITLVTSTQSSPLVTSS-GSMSTLVSSVNADLPIATASADVAADIAKYT 904
             + IT S   S  T VT+  S     S+ GS +T VS+  ++   A+        ++   
Sbjct: 951  SETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1010

Query: 905  SKMMD-AIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTM 963
            S+    +  GT T I +     TT  T A      +     +             +  T 
Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070

Query: 964  AEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYP 1023
            +E   +   + +                A  ET             ++     T+     
Sbjct: 1071 SETTTASTADLETTTVSTSGSGTTTASTAGSETT-----------TVYITGSKTTTASTE 1119

Query: 1024 CQQAHWPEHMKSCTQSATAPQQEADAEVNT--ETLNKSSQGSSSSTQSAPSE--TASASK 1079
              +A       S T +A+    E      T  ET   S+ GS ++T SA     T ++++
Sbjct: 1120 GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE 1179

Query: 1080 EKETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTR--- 1136
              ET+   +  S +T   +   ET ++   GS   +  +  +++S  SS     +T    
Sbjct: 1180 GSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFII 1239

Query: 1137 SDHNTSTSTKSLLPKESRL 1155
                T  ST SL P  + L
Sbjct: 1240 GSETTIASTASLEPTATSL 1258



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 77/402 (19%), Positives = 151/402 (37%), Gaps = 45/402 (11%)

Query: 765  KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRP 824
            +T  ++T GS +   +P  ++++  + +     TTST+ +   T  +  +  +       
Sbjct: 34   ETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGS 93

Query: 825  LLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVN 884
                 TA +    V  S T  +  +  +  + T T  T++  + + +++GS +T VS+V 
Sbjct: 94   ETTVSTAGSETTTV--SITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVG 151

Query: 885  ADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKL 944
            ++   A  +AD     A  T          MT ++   S+  T ST         E   +
Sbjct: 152  SETTTA-YTADSETTAASTTG-------SEMTTVFTAGSETITPSTAGS------ETTTV 197

Query: 945  QWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCAN 1004
                 +  +      E T A    S       + +E  K      +  V     +   A+
Sbjct: 198  STAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAAS 257

Query: 1005 CKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSS 1064
             +         NT++           E  K+ T S T  +  A +   +E    S+ GS 
Sbjct: 258  TEDSET-----NTAF----------TEDSKTTTASTTGFETTAASTTGSEPTMASTMGSE 302

Query: 1065 S-------------STQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGS 1111
            +             ST S+   T  A+  +   A       +T+  +GS  T +SI +GS
Sbjct: 303  TTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASI-MGS 361

Query: 1112 NQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKES 1153
               +D +  ++++ +S++    +T S   +  +T S    E+
Sbjct: 362  ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSET 403



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 111/555 (20%), Positives = 187/555 (33%), Gaps = 60/555 (10%)

Query: 400  DPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLS--GGTGRRISLSDMPRSPMSTN 457
            D  N +A TA  +         + T +          S  G     +S +D   + +ST 
Sbjct: 600  DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659

Query: 458  SSVHTGSDVE--QDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFS 515
             S  T +  E  +     AT S  + S E       S     +TK    GS + +     
Sbjct: 660  GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEG 719

Query: 516  PQLSAPITTKTDKTS--------TTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLIS 567
             +++    T ++ T+        TT S        +         + +   ++T   ++ 
Sbjct: 720  SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 779

Query: 568  PKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDE 627
             +  + S   +  + T  S  +       +E+  T +  + + ++    ++ SE I    
Sbjct: 780  SETTMAST--IGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAST 837

Query: 628  QKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKA 687
              S  E   T   EG +     ++ +     T   E  E   +T+  SE          A
Sbjct: 838  AGS--ETTTTTSTEGSETTT--ASTEGSETTTASTESSETTTATTIGSETTT-------A 886

Query: 688  SPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHS--GRE 745
            S E  +  +   +           G + T + T        SE   V   G + +    E
Sbjct: 887  STEGSETTTTSTE-----------GSETTTAST------EGSEITTVSTTGSETTTASTE 929

Query: 746  GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGA---TATTSTS 802
            G +      E S    V      + TV +     T V T  S  T+A+ A   T T ST+
Sbjct: 930  GSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTA 989

Query: 803  STVTVTAPAP-------AATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPST 855
             + T TA          ++TGS          + T  + +     + T    E T   +T
Sbjct: 990  GSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTT 1049

Query: 856  STITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTM 915
             + T  TST+ S   T S + S   ++  ADL   T S   +      T+          
Sbjct: 1050 GSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTA------GSET 1103

Query: 916  TEIYNDLSKNTTGST 930
            T +Y   SK TT ST
Sbjct: 1104 TTVYITGSKTTTAST 1118



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 133/752 (17%), Positives = 263/752 (34%), Gaps = 87/752 (11%)

Query: 434  PVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKST 493
            P  +G     +S +    + +ST  S  T +     A  + T++    SE +     K +
Sbjct: 187  PSTAGSETTTVSTAGSETTTVSTTGSETTTAST---AHSETTAASTMGSETT-----KVS 238

Query: 494  ASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELS 553
             + + T    AGS + +      + +   T   D  +TT S        +        ++
Sbjct: 239  TAGSETTVSTAGSETTAASTEDSETNTAFTE--DSKTTTASTTGFETTAASTTGSEPTMA 296

Query: 554  ESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSE 613
             ++  ++T    I P+    S     +     +    +  + +  +  T V  + SE + 
Sbjct: 297  STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET-TTVSTTGSETTT 355

Query: 614  KSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS---AVKKKPKPTNPVEIKEELKS 670
             S    SE  +D    S+     TE  E      E S    V      T  V I +  ++
Sbjct: 356  ASIMG-SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS-ET 413

Query: 671  TSPASEKADPGAVKDKA--SPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSD 728
            T+  +E ++  AV      +     + SE    S    +      + +++ TV     + 
Sbjct: 414  TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTV---TTAG 470

Query: 729  SESELVIDLGED-----HSGRE-------GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHS 776
            SE++     G +     ++G E       G        E S    V       TTV +  
Sbjct: 471  SETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530

Query: 777  PPETPVLTRSSAQTSAAGATATTSTSST----VTVTAPAPAATGSPVKKQRPLLPKETAP 832
               T V T  S  T+ +     T+T+ST    +T  +   A T +   +        TA 
Sbjct: 531  SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAG 590

Query: 833  AVQRVVWNS------STVQQKEITQSPSTSTITLVTSTQSSPLVTSS--GSMSTLVSSVN 884
            +    V  +      ++    E T + +T + T   ST SS   T+S  GS +T VS+ +
Sbjct: 591  SETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTD 650

Query: 885  ADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKL 944
            ++  + + +       +   S+       T++   ++ + +T GS    +     E  K+
Sbjct: 651  SETTMVSTTGSERTITSTEGSETT-----TVSATGSETTVSTEGSGTTTVSITGSETTKV 705

Query: 945  QWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCAN 1004
                 +  +      E+T A +  S     +   A  +            ET       +
Sbjct: 706  STTGSETTTTSTEGSEITTASITGS-----ETTTASTEGSETTTASTEGSETTSASTTGS 760

Query: 1005 CKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSS 1064
                                         ++ T S T+ +    + + +ET   S+ GS 
Sbjct: 761  -----------------------------ETTTASTTSSETTMASIMGSETTMASTIGSE 791

Query: 1065 S---STQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSN 1121
            +   ST S+   T      + T A  +    +T+  +GS   P+S        +  +  +
Sbjct: 792  TTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGS 851

Query: 1122 KSSWSSSDEKRGSTRSDHNTSTSTKSLLPKES 1153
            +++ +S++    +T S  ++ T+T + +  E+
Sbjct: 852  ETTTASTEGSETTTASTESSETTTATTIGSET 883



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 82/400 (20%), Positives = 156/400 (39%), Gaps = 39/400 (9%)

Query: 760  QDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPV 819
            +  V      TT  S +  ET +++   ++T+     +TTS+ +TVT TA +   T S V
Sbjct: 94   ETTVSTAGSETTTVSITGTETTMVSAMGSETTT---NSTTSSETTVTSTAGSETTTVSTV 150

Query: 820  KKQRP---LLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSM 876
              +         ET  A       S+T  +     +  + TIT  T+   +  V+++GS 
Sbjct: 151  GSETTTAYTADSETTAA-------STTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSE 203

Query: 877  STLVSSVNADLPIAT---ASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGST-IA 932
            +T VS+  ++   A+   +    A+ +   T+K+  A  G+ T +    S+ T  ST  +
Sbjct: 204  TTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA--GSETTVSTAGSETTAASTEDS 261

Query: 933  EIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQA 992
            E      E  K         +      E T A    S       + + +  +  +     
Sbjct: 262  ETNTAFTEDSK-------TTTASTTGFETTAA----STTGSEPTMASTMGSETTMASTIG 310

Query: 993  VDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSAT--APQQEADAE 1050
             + TK     A+ +   +F     T        +        S T +A+    +   D+ 
Sbjct: 311  PETTKVS--TASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDST 368

Query: 1051 VNTETLNKSSQGS---SSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRET--PS 1105
              +ET   S++GS   ++ST+ + + T S +  + T+   +    +T    GS  T   +
Sbjct: 369  TGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVST 428

Query: 1106 SILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTST 1145
            ++   +   ++ S    +S S S+    ST     T+ +T
Sbjct: 429  TVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTT 468



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 92/473 (19%), Positives = 169/473 (35%), Gaps = 24/473 (5%)

Query: 432  SKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDK 491
            S+   +  TG   + +    S  +  S + + + +      + T    ++S+ +  F + 
Sbjct: 750  SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 809

Query: 492  STASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGS-ILNLNLDRSKAEMDLK 550
            S  + AST   +  ++S +     P  +A   T T  TST GS     + + S+      
Sbjct: 810  SETTIASTTASETTTVSTAGSETIPASTAGSETTTT-TSTEGSETTTASTEGSETTTAST 868

Query: 551  ELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSE 610
            E SE+    +T   + S      +        + E  +      E SE   T V  + SE
Sbjct: 869  ESSET----TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSE--ITTVSTTGSE 922

Query: 611  DSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS----AVKKKPKPTNPVEIKE 666
             +  S +  SE  +   + S+     T   E   +  E S          + T       
Sbjct: 923  TTTAS-TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGS 981

Query: 667  ELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLD 726
            E  + S A  +    +++   +       SE    S    +  +   + +++ TV     
Sbjct: 982  ETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTV---TT 1038

Query: 727  SDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPP--STTVGSHSPPETPVLT 784
            + SE+  V   G + +      ++      +  +     T    +TTV +     T   T
Sbjct: 1039 AGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098

Query: 785  RSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTV 844
              S  T+     + T+T+ST    A   + T S          + T   V   V  ++TV
Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT--TVFTTVSETTTV 1156

Query: 845  QQ--KEITQSPSTSTITLVTSTQSSPLVTSS--GSMSTLVSSVNADLPIATAS 893
                 E T S +  +    TST+ S   T+S  GS +T  S+  ++   A+ S
Sbjct: 1157 STIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS 1209



 Score = 33.9 bits (76), Expect = 0.92
 Identities = 49/229 (21%), Positives = 82/229 (35%), Gaps = 37/229 (16%)

Query: 729  SESELVIDLGEDHS-----GREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSH-------- 775
            SE+  V  +G + +     G E      E  E +       +T  ++T GS         
Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210

Query: 776  SPPETPVLTRSSAQTSAAGATAT---------TSTSSTVTVTAPAPAATGS-----PVKK 821
            S   T   T S   T ++  + T         T+ +ST ++   A + TGS      +  
Sbjct: 1211 SETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITA 1270

Query: 822  QRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVS 881
                    T  +   V+  ++ V  + IT +P + T T  T   +S  VT +  M    S
Sbjct: 1271 SGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRPTASSSVTMAPGMDFTAS 1330

Query: 882  SVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGST 930
            + +  +P           I   TS +  +  G  +       + TTGST
Sbjct: 1331 AASHTVP----------GIVLNTSGLGTSTMGASSTTSAHGVRTTTGST 1369



 Score = 33.1 bits (74), Expect = 1.6
 Identities = 36/142 (25%), Positives = 64/142 (45%), Gaps = 13/142 (9%)

Query: 763  VGKTPPSTTVGSHSPPE-------TPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAAT 815
            V +T   +T+GS +          T   T  S  T+A+ A + T+T+ST        + +
Sbjct: 1150 VSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS 1209

Query: 816  GSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTS---TITLVTSTQSSPL-VT 871
            GS          + + P+      N++ +   E T + + S   T T +T ++++ + +T
Sbjct: 1210 GSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSIT 1269

Query: 872  SSG--SMSTLVSSVNADLPIAT 891
            +SG  + ST VSS    L  AT
Sbjct: 1270 ASGATAASTTVSSTTFVLTKAT 1291


>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1704

 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 81/406 (19%), Positives = 146/406 (35%), Gaps = 26/406 (6%)

Query: 742  SGREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTST 801
            +G E      E  E +       +T   +T GS +   T   T  S  T+ + A +  +T
Sbjct: 549  TGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGT---TAASTAGSETTTVSTADSENTT 605

Query: 802  SSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLV 861
            +ST      + + TGS            TA         +ST   +  T S + S  T+V
Sbjct: 606  ASTADSETTSASTTGSETT---------TASTTSSETTTASTEGSETTTVSTTDSETTMV 656

Query: 862  TSTQSSPLVTSS-GSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYN 920
            ++T S   +TS+ GS +T VS+  ++  ++T  +         +     +  G+ T   +
Sbjct: 657  STTGSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTS 716

Query: 921  DLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAE 980
                  T ++I          E  +            +   T +E   +     +  +A 
Sbjct: 717  TEGSEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMAS 776

Query: 981  VKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSA 1040
            +    E      +     K   A+ K   +F     T+       +        S   S 
Sbjct: 777  IMGS-ETTMASTIGSETTKVSTASSKMTTVFTENSETTIASTTASET----TTVSTAGSE 831

Query: 1041 TAPQQEADAEVNTETLNKSSQGSSSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGS 1100
            T P   A +E  T T  + S+ +++ST+ + + TAS    + T+A       +T    GS
Sbjct: 832  TIPASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGS 891

Query: 1101 RETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTK 1146
              T +S        ++ S +  +S   S+    ST     T+ ST+
Sbjct: 892  ETTTTS--------TEGSETTTASTEGSEITTVSTTGSETTTASTE 929



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 141/739 (19%), Positives = 262/739 (35%), Gaps = 52/739 (7%)

Query: 440  TGRRISLSDMPRSPMSTNSSVHTGSDVEQDA-EKKATSSHFSASEESMDFL----DKSTA 494
            TG   + +    S M+T S+  TG++   D+ E   T++  +A  E+        + +TA
Sbjct: 549  TGLETTTTSTEGSEMTTVST--TGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTA 606

Query: 495  SPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKE--L 552
            S A ++T  A S +GS    +   S+  TT + + S T ++   + + +       E  +
Sbjct: 607  STADSETTSA-STTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTI 665

Query: 553  SESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDS 612
            + +   ++T V     +  + +        +I   +        SE   T+ E S+   +
Sbjct: 666  TSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTA 725

Query: 613  EKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTS 672
              + S  +   ++  + +    E +E         E +        T    I      T+
Sbjct: 726  SITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGS--ETT 783

Query: 673  PASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESE 732
             AS           AS +    F+E ++ +       +     +++ TV     + SE+ 
Sbjct: 784  MASTIGSETTKVSTASSKMTTVFTENSETT-------IASTTASETTTVST---AGSETI 833

Query: 733  LVIDLGEDHS------GREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRS 786
                 G + +      G E      E  E +       +T  +TT+GS +   T   T  
Sbjct: 834  PASTAGSETTTTTSTEGSETTTASTEGSETTTASTESSETTTATTIGSET---TTASTEG 890

Query: 787  SAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQ-RVVWNSSTVQ 845
            S  T+ +   + T+T+ST        + TGS          + T  + +   +   ST  
Sbjct: 891  SETTTTSTEGSETTTASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTG 950

Query: 846  QKEITQSPSTSTITLVTSTQSSPLVTSS-GSMSTLVSSVNADLPIATASADVAADIAKYT 904
             + IT S   S  T VT+  S     S+ GS +T VS+  ++   A+        ++   
Sbjct: 951  SETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTG 1010

Query: 905  SKMMD-AIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKLQWLHQQELSEMKHNLELTM 963
            S+    +  GT T I +     TT  T A      +     +             +  T 
Sbjct: 1011 SETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTG 1070

Query: 964  AEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCANCKKEAIFYCCWNTSYCDYP 1023
            +E   +   + +                A  ET             ++     T+     
Sbjct: 1071 SETTTASTADLETTTVSTSGSGTTTASTAGSETT-----------TVYITGSKTTTASTE 1119

Query: 1024 CQQAHWPEHMKSCTQSATAPQQEADAEVNT--ETLNKSSQGSSSSTQSAPSE--TASASK 1079
              +A       S T +A+    E      T  ET   S+ GS ++T SA     T ++++
Sbjct: 1120 GSEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE 1179

Query: 1080 EKETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSNKSSWSSSDEKRGSTR--- 1136
              ET+   +  S +T   +   ET ++   GS   +  +  +++S  SS     +T    
Sbjct: 1180 GSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSETSTPSSAGSETNTAFII 1239

Query: 1137 SDHNTSTSTKSLLPKESRL 1155
                T  ST SL P  + L
Sbjct: 1240 GSETTIASTASLEPTATSL 1258



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 77/402 (19%), Positives = 151/402 (37%), Gaps = 45/402 (11%)

Query: 765  KTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRP 824
            +T  ++T GS +   +P  ++++  + +     TTST+ +   T  +  +  +       
Sbjct: 34   ETTTASTAGSETTTPSPTGSQTTIVSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGS 93

Query: 825  LLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVSSVN 884
                 TA +    V  S T  +  +  +  + T T  T++  + + +++GS +T VS+V 
Sbjct: 94   ETTVSTAGSETTTV--SITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVG 151

Query: 885  ADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKL 944
            ++   A  +AD     A  T          MT ++   S+  T ST         E   +
Sbjct: 152  SETTTA-YTADSETTAASTTG-------SEMTTVFTAGSETITPSTAGS------ETTTV 197

Query: 945  QWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCAN 1004
                 +  +      E T A    S       + +E  K      +  V     +   A+
Sbjct: 198  STAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSETTAAS 257

Query: 1005 CKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSS 1064
             +         NT++           E  K+ T S T  +  A +   +E    S+ GS 
Sbjct: 258  TEDSET-----NTAF----------TEDSKTTTASTTGFETTAASTTGSEPTMASTMGSE 302

Query: 1065 S-------------STQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGS 1111
            +             ST S+   T  A+  +   A       +T+  +GS  T +SI +GS
Sbjct: 303  TTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASI-MGS 361

Query: 1112 NQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTSTKSLLPKES 1153
               +D +  ++++ +S++    +T S   +  +T S    E+
Sbjct: 362  ETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSET 403



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 111/555 (20%), Positives = 187/555 (33%), Gaps = 60/555 (10%)

Query: 400  DPTNPSAGTAKIDKQEKVKLNFDMTASPKILMSKPVLS--GGTGRRISLSDMPRSPMSTN 457
            D  N +A TA  +         + T +          S  G     +S +D   + +ST 
Sbjct: 600  DSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTT 659

Query: 458  SSVHTGSDVE--QDAEKKATSSHFSASEESMDFLDKSTASPASTKTGQAGSLSGSPKPFS 515
             S  T +  E  +     AT S  + S E       S     +TK    GS + +     
Sbjct: 660  GSERTITSTEGSETTTVSATGSETTVSTEGSGTTTVSITGSETTKVSTTGSETTTTSTEG 719

Query: 516  PQLSAPITTKTDKTS--------TTGSILNLNLDRSKAEMDLKELSESVQQQSTPVPLIS 567
             +++    T ++ T+        TT S        +         + +   ++T   ++ 
Sbjct: 720  SEITTASITGSETTTASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMG 779

Query: 568  PKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSEKSDSSDSEYISDDE 627
             +  + S   +  + T  S  +       +E+  T +  + + ++    ++ SE I    
Sbjct: 780  SETTMAST--IGSETTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPAST 837

Query: 628  QKSKNEPEDTEDKEGCQMDKEPSAVKKKPKPTNPVEIKEELKSTSPASEKADPGAVKDKA 687
              S  E   T   EG +     ++ +     T   E  E   +T+  SE          A
Sbjct: 838  AGS--ETTTTTSTEGSETTT--ASTEGSETTTASTESSETTTATTIGSETTT-------A 886

Query: 688  SPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSDSESELVIDLGEDHS--GRE 745
            S E  +  +   +           G + T + T        SE   V   G + +    E
Sbjct: 887  STEGSETTTTSTE-----------GSETTTAST------EGSEITTVSTTGSETTTASTE 929

Query: 746  GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGA---TATTSTS 802
            G +      E S    V      + TV +     T V T  S  T+A+ A   T T ST+
Sbjct: 930  GSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTA 989

Query: 803  STVTVTAPAP-------AATGSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPST 855
             + T TA          ++TGS          + T  + +     + T    E T   +T
Sbjct: 990  GSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTT 1049

Query: 856  STITLVTSTQSSPLVTSSGSMSTLVSSVNADLPIATASADVAADIAKYTSKMMDAIKGTM 915
             + T  TST+ S   T S + S   ++  ADL   T S   +      T+          
Sbjct: 1050 GSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTA------GSET 1103

Query: 916  TEIYNDLSKNTTGST 930
            T +Y   SK TT ST
Sbjct: 1104 TTVYITGSKTTTAST 1118



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 133/752 (17%), Positives = 263/752 (34%), Gaps = 87/752 (11%)

Query: 434  PVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDKST 493
            P  +G     +S +    + +ST  S  T +     A  + T++    SE +     K +
Sbjct: 187  PSTAGSETTTVSTAGSETTTVSTTGSETTTAST---AHSETTAASTMGSETT-----KVS 238

Query: 494  ASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGSILNLNLDRSKAEMDLKELS 553
             + + T    AGS + +      + +   T   D  +TT S        +        ++
Sbjct: 239  TAGSETTVSTAGSETTAASTEDSETNTAFTE--DSKTTTASTTGFETTAASTTGSEPTMA 296

Query: 554  ESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSEDSE 613
             ++  ++T    I P+    S     +     +    +  + +  +  T V  + SE + 
Sbjct: 297  STMGSETTMASTIGPETTKVSTASSEVTTVFAAGSETIRASTVGSET-TTVSTTGSETTT 355

Query: 614  KSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS---AVKKKPKPTNPVEIKEELKS 670
             S    SE  +D    S+     TE  E      E S    V      T  V I +  ++
Sbjct: 356  ASIMG-SETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDS-ET 413

Query: 671  TSPASEKADPGAVKDKA--SPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLDSD 728
            T+  +E ++  AV      +     + SE    S    +      + +++ TV     + 
Sbjct: 414  TTTCTEGSEMTAVSTTVFETTTASTEGSEITIASTSDSETTTASTEGSETTTV---TTAG 470

Query: 729  SESELVIDLGED-----HSGRE-------GRKNKKEPKEPSPKQDVVGKTPPSTTVGSHS 776
            SE++     G +     ++G E       G        E S    V       TTV +  
Sbjct: 471  SETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEG 530

Query: 777  PPETPVLTRSSAQTSAAGATATTSTSST----VTVTAPAPAATGSPVKKQRPLLPKETAP 832
               T V T  S  T+ +     T+T+ST    +T  +   A T +   +        TA 
Sbjct: 531  SENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAG 590

Query: 833  AVQRVVWNS------STVQQKEITQSPSTSTITLVTSTQSSPLVTSS--GSMSTLVSSVN 884
            +    V  +      ++    E T + +T + T   ST SS   T+S  GS +T VS+ +
Sbjct: 591  SETTTVSTADSENTTASTADSETTSASTTGSETTTASTTSSETTTASTEGSETTTVSTTD 650

Query: 885  ADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGSTIAEIRRLRIEIEKL 944
            ++  + + +       +   S+       T++   ++ + +T GS    +     E  K+
Sbjct: 651  SETTMVSTTGSERTITSTEGSETT-----TVSATGSETTVSTEGSGTTTVSITGSETTKV 705

Query: 945  QWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQAVDETKKKQWCAN 1004
                 +  +      E+T A +  S     +   A  +            ET       +
Sbjct: 706  STTGSETTTTSTEGSEITTASITGS-----ETTTASTEGSETTTASTEGSETTSASTTGS 760

Query: 1005 CKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSATAPQQEADAEVNTETLNKSSQGSS 1064
                                         ++ T S T+ +    + + +ET   S+ GS 
Sbjct: 761  -----------------------------ETTTASTTSSETTMASIMGSETTMASTIGSE 791

Query: 1065 S---STQSAPSETASASKEKETSAEKSKESGSTLDLSGSRETPSSILLGSNQGSDHSRSN 1121
            +   ST S+   T      + T A  +    +T+  +GS   P+S        +  +  +
Sbjct: 792  TTKVSTASSKMTTVFTENSETTIASTTASETTTVSTAGSETIPASTAGSETTTTTSTEGS 851

Query: 1122 KSSWSSSDEKRGSTRSDHNTSTSTKSLLPKES 1153
            +++ +S++    +T S  ++ T+T + +  E+
Sbjct: 852  ETTTASTEGSETTTASTESSETTTATTIGSET 883



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 82/400 (20%), Positives = 156/400 (39%), Gaps = 39/400 (9%)

Query: 760  QDVVGKTPPSTTVGSHSPPETPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPV 819
            +  V      TT  S +  ET +++   ++T+     +TTS+ +TVT TA +   T S V
Sbjct: 94   ETTVSTAGSETTTVSITGTETTMVSAMGSETTT---NSTTSSETTVTSTAGSETTTVSTV 150

Query: 820  KKQRP---LLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSM 876
              +         ET  A       S+T  +     +  + TIT  T+   +  V+++GS 
Sbjct: 151  GSETTTAYTADSETTAA-------STTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSE 203

Query: 877  STLVSSVNADLPIAT---ASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGST-IA 932
            +T VS+  ++   A+   +    A+ +   T+K+  A  G+ T +    S+ T  ST  +
Sbjct: 204  TTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTA--GSETTVSTAGSETTAASTEDS 261

Query: 933  EIRRLRIEIEKLQWLHQQELSEMKHNLELTMAEMRQSLEQERDRLIAEVKKQLELEKQQA 992
            E      E  K         +      E T A    S       + + +  +  +     
Sbjct: 262  ETNTAFTEDSK-------TTTASTTGFETTAA----STTGSEPTMASTMGSETTMASTIG 310

Query: 993  VDETKKKQWCANCKKEAIFYCCWNTSYCDYPCQQAHWPEHMKSCTQSAT--APQQEADAE 1050
             + TK     A+ +   +F     T        +        S T +A+    +   D+ 
Sbjct: 311  PETTKVS--TASSEVTTVFAAGSETIRASTVGSETTTVSTTGSETTTASIMGSETSTDST 368

Query: 1051 VNTETLNKSSQGS---SSSTQSAPSETASASKEKETSAEKSKESGSTLDLSGSRET--PS 1105
              +ET   S++GS   ++ST+ + + T S +  + T+   +    +T    GS  T   +
Sbjct: 369  TGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSETTTTCTEGSEMTAVST 428

Query: 1106 SILLGSNQGSDHSRSNKSSWSSSDEKRGSTRSDHNTSTST 1145
            ++   +   ++ S    +S S S+    ST     T+ +T
Sbjct: 429  TVFETTTASTEGSEITIASTSDSETTTASTEGSETTTVTT 468



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 92/473 (19%), Positives = 169/473 (35%), Gaps = 24/473 (5%)

Query: 432  SKPVLSGGTGRRISLSDMPRSPMSTNSSVHTGSDVEQDAEKKATSSHFSASEESMDFLDK 491
            S+   +  TG   + +    S  +  S + + + +      + T    ++S+ +  F + 
Sbjct: 750  SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 809

Query: 492  STASPASTKTGQAGSLSGSPKPFSPQLSAPITTKTDKTSTTGS-ILNLNLDRSKAEMDLK 550
            S  + AST   +  ++S +     P  +A   T T  TST GS     + + S+      
Sbjct: 810  SETTIASTTASETTTVSTAGSETIPASTAGSETTTT-TSTEGSETTTASTEGSETTTAST 868

Query: 551  ELSESVQQQSTPVPLISPKRQIRSRFQLNLDKTIESCKAQLGINEISEDVYTAVEHSDSE 610
            E SE+    +T   + S      +        + E  +      E SE   T V  + SE
Sbjct: 869  ESSET----TTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSE--ITTVSTTGSE 922

Query: 611  DSEKSDSSDSEYISDDEQKSKNEPEDTEDKEGCQMDKEPS----AVKKKPKPTNPVEIKE 666
             +  S +  SE  +   + S+     T   E   +  E S          + T       
Sbjct: 923  TTTAS-TEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGS 981

Query: 667  ELKSTSPASEKADPGAVKDKASPEPEKDFSEKAKPSPHPIKDKLKGKDETDSPTVHLGLD 726
            E  + S A  +    +++   +       SE    S    +  +   + +++ TV     
Sbjct: 982  ETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTV---TT 1038

Query: 727  SDSESELVIDLGEDHSGREGRKNKKEPKEPSPKQDVVGKTPP--STTVGSHSPPETPVLT 784
            + SE+  V   G + +      ++      +  +     T    +TTV +     T   T
Sbjct: 1039 AGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTAST 1098

Query: 785  RSSAQTSAAGATATTSTSSTVTVTAPAPAATGSPVKKQRPLLPKETAPAVQRVVWNSSTV 844
              S  T+     + T+T+ST    A   + T S          + T   V   V  ++TV
Sbjct: 1099 AGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT--TVFTTVSETTTV 1156

Query: 845  QQ--KEITQSPSTSTITLVTSTQSSPLVTSS--GSMSTLVSSVNADLPIATAS 893
                 E T S +  +    TST+ S   T+S  GS +T  S+  ++   A+ S
Sbjct: 1157 STIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS 1209



 Score = 33.9 bits (76), Expect = 0.92
 Identities = 49/229 (21%), Positives = 82/229 (35%), Gaps = 37/229 (16%)

Query: 729  SESELVIDLGEDHS-----GREGRKNKKEPKEPSPKQDVVGKTPPSTTVGSH-------- 775
            SE+  V  +G + +     G E      E  E +       +T  ++T GS         
Sbjct: 1151 SETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSG 1210

Query: 776  SPPETPVLTRSSAQTSAAGATAT---------TSTSSTVTVTAPAPAATGS-----PVKK 821
            S   T   T S   T ++  + T         T+ +ST ++   A + TGS      +  
Sbjct: 1211 SETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITA 1270

Query: 822  QRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTSTITLVTSTQSSPLVTSSGSMSTLVS 881
                    T  +   V+  ++ V  + IT +P + T T  T   +S  VT +  M    S
Sbjct: 1271 SGATAASTTVSSTTFVLTKATDVSIQPITNTPMSGTRTTGTRPTASSSVTMAPGMDFTAS 1330

Query: 882  SVNADLPIATASADVAADIAKYTSKMMDAIKGTMTEIYNDLSKNTTGST 930
            + +  +P           I   TS +  +  G  +       + TTGST
Sbjct: 1331 AASHTVP----------GIVLNTSGLGTSTMGASSTTSAHGVRTTTGST 1369



 Score = 33.1 bits (74), Expect = 1.6
 Identities = 36/142 (25%), Positives = 64/142 (45%), Gaps = 13/142 (9%)

Query: 763  VGKTPPSTTVGSHSPPE-------TPVLTRSSAQTSAAGATATTSTSSTVTVTAPAPAAT 815
            V +T   +T+GS +          T   T  S  T+A+ A + T+T+ST        + +
Sbjct: 1150 VSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS 1209

Query: 816  GSPVKKQRPLLPKETAPAVQRVVWNSSTVQQKEITQSPSTS---TITLVTSTQSSPL-VT 871
            GS          + + P+      N++ +   E T + + S   T T +T ++++ + +T
Sbjct: 1210 GSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSIT 1269

Query: 872  SSG--SMSTLVSSVNADLPIAT 891
            +SG  + ST VSS    L  AT
Sbjct: 1270 ASGATAASTTVSSTTFVLTKAT 1291


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.123    0.355 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,176,755
Number of Sequences: 37866
Number of extensions: 2423563
Number of successful extensions: 25183
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 361
Number of HSP's successfully gapped in prelim test: 1117
Number of HSP's that attempted gapping in prelim test: 13983
Number of HSP's gapped (non-prelim): 8287
length of query: 1160
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1047
effective length of database: 13,968,660
effective search space: 14625187020
effective search space used: 14625187020
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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