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Search of human proteins with 33946297
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33946297 zinc finger protein 326 isoform 1 [Homo sapiens]
(582 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33946297 zinc finger protein 326 isoform 1 [Homo sapiens] 1194 0.0
gi|5031579 A-kinase anchor protein 8 [Homo sapiens] 176 7e-44
gi|49472841 A kinase (PRKA) anchor protein 8-like [Homo sapiens] 172 8e-43
gi|33946295 zinc finger protein 326 isoform 3 [Homo sapiens] 159 7e-39
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 61 2e-09
gi|21735415 centromere protein B [Homo sapiens] 60 4e-09
gi|62122917 filaggrin family member 2 [Homo sapiens] 60 6e-09
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 59 9e-09
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] 56 8e-08
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] 56 8e-08
gi|58761548 tau tubulin kinase 1 [Homo sapiens] 56 8e-08
gi|17975763 myelin transcription factor 1 [Homo sapiens] 55 2e-07
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 55 2e-07
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 55 2e-07
gi|57864582 hornerin [Homo sapiens] 54 4e-07
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 54 5e-07
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 54 5e-07
gi|33946282 hypothetical protein LOC25962 isoform 1 [Homo sapiens] 54 5e-07
gi|33946280 hypothetical protein LOC25962 isoform 2 [Homo sapiens] 54 5e-07
gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b... 53 9e-07
gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isofor... 52 1e-06
gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform... 52 1e-06
gi|153252068 testes-specific heterogenous nuclear ribonucleoprot... 52 1e-06
gi|223890219 RNA binding motif protein, X-linked-like 3 [Homo sa... 52 2e-06
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 52 2e-06
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 52 2e-06
gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo sap... 52 2e-06
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 51 3e-06
gi|212549553 interleukin enhancer binding factor 3 isoform d [Ho... 51 3e-06
gi|24234750 interleukin enhancer binding factor 3 isoform a [Hom... 51 3e-06
>gi|33946297 zinc finger protein 326 isoform 1 [Homo sapiens]
Length = 582
Score = 1194 bits (3090), Expect = 0.0
Identities = 582/582 (100%), Positives = 582/582 (100%)
Query: 1 MDFEDDYTHSACRNTYQGFNGMDRDYGPGSYGGMDRDYGHGSYGGQRSMDSYLNQSYGMD 60
MDFEDDYTHSACRNTYQGFNGMDRDYGPGSYGGMDRDYGHGSYGGQRSMDSYLNQSYGMD
Sbjct: 1 MDFEDDYTHSACRNTYQGFNGMDRDYGPGSYGGMDRDYGHGSYGGQRSMDSYLNQSYGMD 60
Query: 61 NHSGGGGGSRFGPYESYDSRSSLGGRDLYRSGYGFNEPEQSRFGGSYGGRFESSYRNSLD 120
NHSGGGGGSRFGPYESYDSRSSLGGRDLYRSGYGFNEPEQSRFGGSYGGRFESSYRNSLD
Sbjct: 61 NHSGGGGGSRFGPYESYDSRSSLGGRDLYRSGYGFNEPEQSRFGGSYGGRFESSYRNSLD 120
Query: 121 SFGGRNQGGSSWEAPYSRSKLRPGFMEDRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAY 180
SFGGRNQGGSSWEAPYSRSKLRPGFMEDRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAY
Sbjct: 121 SFGGRNQGGSSWEAPYSRSKLRPGFMEDRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAY 180
Query: 181 PESTFGSRNYDAFGGPSTGRGRGRGHMGDFGSIHRPGIVVDYQNKSTNVTVAAARGIKRK 240
PESTFGSRNYDAFGGPSTGRGRGRGHMGDFGSIHRPGIVVDYQNKSTNVTVAAARGIKRK
Sbjct: 181 PESTFGSRNYDAFGGPSTGRGRGRGHMGDFGSIHRPGIVVDYQNKSTNVTVAAARGIKRK 240
Query: 241 MMQPFNKPSGTFIKKPKLAKPMEKISLSKSPTKTDPKNEEEEKRRIEARREKQRRRREKN 300
MMQPFNKPSGTFIKKPKLAKPMEKISLSKSPTKTDPKNEEEEKRRIEARREKQRRRREKN
Sbjct: 241 MMQPFNKPSGTFIKKPKLAKPMEKISLSKSPTKTDPKNEEEEKRRIEARREKQRRRREKN 300
Query: 301 SEKYGDGYRMAFTCSFCKFRTFEEKDIELHLESSSHQETLDHIQKQTKFDKVVMEFLHEC 360
SEKYGDGYRMAFTCSFCKFRTFEEKDIELHLESSSHQETLDHIQKQTKFDKVVMEFLHEC
Sbjct: 301 SEKYGDGYRMAFTCSFCKFRTFEEKDIELHLESSSHQETLDHIQKQTKFDKVVMEFLHEC 360
Query: 361 MVNKFKKTSIRKQQTNNQTEVVKIIEKDVMEGVTVDDHMMKVETVHCSACSVYIPALHSS 420
MVNKFKKTSIRKQQTNNQTEVVKIIEKDVMEGVTVDDHMMKVETVHCSACSVYIPALHSS
Sbjct: 361 MVNKFKKTSIRKQQTNNQTEVVKIIEKDVMEGVTVDDHMMKVETVHCSACSVYIPALHSS 420
Query: 421 VQQHLKSPDHIKGKQAYKEQIKRESVLTATSILNNPIVKARYERFVKGENPFEIQDHSQD 480
VQQHLKSPDHIKGKQAYKEQIKRESVLTATSILNNPIVKARYERFVKGENPFEIQDHSQD
Sbjct: 421 VQQHLKSPDHIKGKQAYKEQIKRESVLTATSILNNPIVKARYERFVKGENPFEIQDHSQD 480
Query: 481 QQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGGIEGEGNIQGVGE 540
QQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGGIEGEGNIQGVGE
Sbjct: 481 QQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGGIEGEGNIQGVGE 540
Query: 541 GGEVGVVGEVEGVGEVEEVEELEEETAKEEPADFPVEQPEEN 582
GGEVGVVGEVEGVGEVEEVEELEEETAKEEPADFPVEQPEEN
Sbjct: 541 GGEVGVVGEVEGVGEVEEVEELEEETAKEEPADFPVEQPEEN 582
>gi|5031579 A-kinase anchor protein 8 [Homo sapiens]
Length = 692
Score = 176 bits (445), Expect = 7e-44
Identities = 184/633 (29%), Positives = 270/633 (42%), Gaps = 110/633 (17%)
Query: 5 DDYTHSACRNTYQGFNGMDRDYGPGSYGGMDRDYGH----------GSYGGQRSMDSY-- 52
++Y + +NT G YGP S+ + G SYG + D+
Sbjct: 33 ENYNYYGAQNT-SVTTGATYSYGPASWEAAKANDGGLAAGAPAMHMASYGPEPCTDNSDS 91
Query: 53 ----LNQSYGMDNHSGGGGGS--------------RFGPYESYDSRSSLGGRDLYRSGYG 94
+NQ M + GG GGS RF P+ESYDSR L + YR Y
Sbjct: 92 LIAKINQRLDMMSKEGGRGGSGGGGEGIQDRESSFRFQPFESYDSRPCLPEHNPYRPSYS 151
Query: 95 FNEPEQ--SRFGGSYGGRFE-----SSYRNSLDSF-GGRNQGGSSWEAPYSRSKLRPGFM 146
++ S GS+GG++ + R SLD F GR QG RS
Sbjct: 152 YDYEFDLGSDRNGSFGGQYSECRDPARERGSLDGFMRGRGQGRFQ-----DRSNPGTFMR 206
Query: 147 EDRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAY---PESTF--------GSRNYDAFGG 195
D +S S+P + VG RG G P+ P S F G GG
Sbjct: 207 SDPFVPPAASSEPLSTPWNELNYVGGRGLGGPSPSRPPPSLFSQSMAPDYGVMGMQGAGG 266
Query: 196 PST----GRGRGRGHMGDFGSIHRPGIVVDYQNKSTNVTVAAARGIKRKMMQPFNKPS-- 249
+ G GR + M D R G + + T G KRK Q + +P
Sbjct: 267 YDSTMPYGCGRSQPRMRDRDRPKRRG----FDRFGPDGT-----GRKRKQFQLYEEPDTK 317
Query: 250 -------GTFIKKPKLAKPME--------KISLSKSPTKTDPKNEEEEKRRIEARREKQR 294
G F + A + L S + K +E+E ++ RREKQR
Sbjct: 318 LARVDSEGDFSENDDAAGDFRSGDEEFKGEDELCDSGRQRGEKEDEDED--VKKRREKQR 375
Query: 295 RRREKNSEKYGDGYRMAFTCSFCKFRTFEEKDIELHLESSSHQETLDHIQKQTKFDKVVM 354
RR ++ ++ D R+ F CS CKFR+F++++I+ HL+S H+ETL I TK +
Sbjct: 376 RR-DRTRDRAAD--RIQFACSVCKFRSFDDEEIQKHLQSKFHKETLRFIS--TKLPDKTV 430
Query: 355 EFLHECMVNKFKKTSIRKQQTNNQTEVVKIIEKDVMEGVTVDDHMMKVETVHCSACSVYI 414
EFL E +VN+ KK R+Q+ + E K + D +G+ + K+E HC AC + I
Sbjct: 431 EFLQEYIVNRNKKIEKRRQELMEK-ETAKP-KPDPFKGIGQEHFFKKIEAAHCLACDMLI 488
Query: 415 PALHSSVQQHLKSPDHIKGKQAYKEQIKRESVLTATSILNNPIVKARYERFVKGENPFEI 474
PA +Q+HL S DH ++ EQ K+ S+ A S+LNN + E+++KGE+PF
Sbjct: 489 PAQPQLLQRHLHSVDHNHNRRLAAEQFKKTSLHVAKSVLNNRHIVKMLEKYLKGEDPF-- 546
Query: 475 QDHSQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGGIEGEG- 533
+ D ++EGD + ED++E EEV + + EV ++GEG
Sbjct: 547 TSETVDPEMEGD-----------DNLGGEDKKETPEEVA-ADVLAEVITAAVRAVDGEGA 594
Query: 534 -NIQGVGEGGEVGVVGEVEGVGEVEEVEELEEE 565
+ GE E + G + E+L EE
Sbjct: 595 PAPESSGEPAEDEGPTDTAEAGSDPQAEQLLEE 627
>gi|49472841 A kinase (PRKA) anchor protein 8-like [Homo sapiens]
Length = 646
Score = 172 bits (436), Expect = 8e-43
Identities = 164/602 (27%), Positives = 253/602 (42%), Gaps = 144/602 (23%)
Query: 15 TYQGFNGMDRDYGPGSYGGMDRDYG----------------HGSYGGQRSMDSYL---NQ 55
T +G+ G YG G + YG + S G S DS L NQ
Sbjct: 38 TNRGYEGYGYGYGYGQDNTTNYGYGMATSHSWEMPSSDTNANTSASGSASADSVLSRINQ 97
Query: 56 SYGMDNHSG---------GGGGSRFGPYESYDSRSSLGGRDLYRSGYGFNE--PE-QSRF 103
M H G GG R+ YES DSR+ L RDLYRSGY ++E PE + +
Sbjct: 98 RLDMVPHLETDMMQGGVYGSGGERYDSYESCDSRAVLSERDLYRSGYDYSELDPEMEMAY 157
Query: 104 GGSYGGRFESSYRNSLDSFGGRNQGGSSWEAPYSRSKLRPGFMEDRGRENYSSYSSFSSP 163
G Y + D+FG R QG W A +RS GR S Y
Sbjct: 158 EGQYDAYRDQFRMRGNDTFGPRAQG---W-ARDARS----------GRPMASGYG----- 198
Query: 164 HMKPAPVGSRGR---GTPAYPESTF------------GSRNYDAF-GGPSTGRGRGRGHM 207
M P+G+RG+ G P S F G R AF GG G G G G M
Sbjct: 199 RMWEDPMGARGQCMSGASRLP-SLFSQNIIPEYGMFQGMRGGGAFPGGSRFGFGFGNG-M 256
Query: 208 GDFGSIHRPGIVVDYQNKSTNVTVAAARGIKRKMMQPFNKPSGTFIK------------- 254
+ D++ K KRK ++P +
Sbjct: 257 KQMRRTWKTWTTADFRTKKK----------KRKQGGSPDEPDSKATRTDCSDNSDSDNDE 306
Query: 255 --KPKLAKPMEKISLSKSPTKTDPKNEE-------------------------EEKRRIE 287
+ + + +E + ++ D ++EE + KR+++
Sbjct: 307 GTEGEATEGLEGTEAVEKGSRVDGEDEEGKEDGREEGKEDPEKGALTTQDENGQTKRKLQ 366
Query: 288 ARREKQRRRREKNSEKYGDGYRMAFTCSFCKFRTFEEKDIELHLESSSHQETLDHIQKQT 347
A ++ Q +++++ ++ + R+ F CS CK+RTF E ++ HL+S H+E ++ T
Sbjct: 367 AGKKSQDKQKKRQRDRMVE--RIQFVCSLCKYRTFYEDEMASHLDSKFHKEHFKYVG--T 422
Query: 348 KFDKVVMEFLHECMVNKFKKTSIRKQQTNNQTEVVKII--EKDVMEGVTVDDHMMKVETV 405
K K +FL E + NK KKT ++ + ++ I ++D+ + + ++ + KVE
Sbjct: 423 KLPKQTADFLQEYVTNKTKKTEELRKTVEDLDGLIHQIYRDQDLTQEIAMEHFVKKVEAA 482
Query: 406 HCSACSVYIPALHSSVQQHLKSPDHIKGKQAYKEQIKRESVLTATSILNNPIVKARYERF 465
HC+AC ++IP +Q+HLK+ DH + ++ EQ K+ S++ A SILNN ++ + ER+
Sbjct: 483 HCAACDLFIPMQFGIIQKHLKTMDHNRNRRLMMEQSKKSSLMVARSILNNKLISKKLERY 542
Query: 466 VKGENPFEIQDHSQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVR 525
+KGENPF D P EE+E E+ E A + G E + E
Sbjct: 543 LKGENPFT--------------------DSPEEEKEQEEAEGGALDEGAQGEAAGISEGA 582
Query: 526 EG 527
EG
Sbjct: 583 EG 584
>gi|33946295 zinc finger protein 326 isoform 3 [Homo sapiens]
Length = 70
Score = 159 bits (402), Expect = 7e-39
Identities = 70/70 (100%), Positives = 70/70 (100%)
Query: 1 MDFEDDYTHSACRNTYQGFNGMDRDYGPGSYGGMDRDYGHGSYGGQRSMDSYLNQSYGMD 60
MDFEDDYTHSACRNTYQGFNGMDRDYGPGSYGGMDRDYGHGSYGGQRSMDSYLNQSYGMD
Sbjct: 1 MDFEDDYTHSACRNTYQGFNGMDRDYGPGSYGGMDRDYGHGSYGGQRSMDSYLNQSYGMD 60
Query: 61 NHSGGGGGSR 70
NHSGGGGGSR
Sbjct: 61 NHSGGGGGSR 70
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 61.2 bits (147), Expect = 2e-09
Identities = 51/110 (46%), Positives = 60/110 (54%), Gaps = 7/110 (6%)
Query: 479 QDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVE----EVEEVEEVREGGIEGEGN 534
+ ++ EG+ E EE+ E EEE E E EE E GE E E EE E EG EGEG
Sbjct: 947 EGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGE 1006
Query: 535 IQGVGEGGEVGVVGEVEGVGEVEEVE-ELEEETAKEEPADFPVE-QPEEN 582
+G GE GE GEVEG E EE E E EEE +EE + E + EEN
Sbjct: 1007 EEGEGE-GEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEEN 1055
Score = 60.1 bits (144), Expect = 6e-09
Identities = 47/119 (39%), Positives = 59/119 (49%), Gaps = 7/119 (5%)
Query: 467 KGENPFEIQDHSQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVRE 526
+GE E + ++ + EG+EE+ E E E EE+ +EE E EE GE E EE E E
Sbjct: 963 EGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVE 1022
Query: 527 GGIEGEGNIQGVG---EGGEVGVVGEVEGVGEVEEVEELEEETAKEEPADFPVEQPEEN 582
G +EGE +G G EG E G E EG GE EEE EE + EEN
Sbjct: 1023 GEVEGEEG-EGEGEEEEGEEEGEEREKEGEGEENRRNREEEE---EEEGKYQETGEEEN 1077
Score = 58.9 bits (141), Expect = 1e-08
Identities = 50/118 (42%), Positives = 61/118 (51%), Gaps = 8/118 (6%)
Query: 467 KGENPFEIQDHSQDQQIEGDEEDEEKIDEPIEEE---EDEDEEEEAEEVGEVEEVEEVEE 523
KGE E ++ + ++ EG+ E+EE E E E E+E EE E EE GE E E EE
Sbjct: 823 KGEREEE-EEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEE 881
Query: 524 VREGGIEGEGNIQGVGEGGEVGVVGEVEGVGEVEEVEELEEETAKEEPADFPVEQPEE 581
EG EGEG +G GEG E GE E GE E EE E +EE + E EE
Sbjct: 882 --EG--EGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEE 935
Score = 58.9 bits (141), Expect = 1e-08
Identities = 53/127 (41%), Positives = 64/127 (50%), Gaps = 12/127 (9%)
Query: 467 KGENPFEIQDHSQDQQIEGDEEDEE---KIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEE 523
+GE E + +++ EG+ E+EE K +E EE E E EEEE E GE E E EE
Sbjct: 892 EGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEE 951
Query: 524 V-----REGGIEGEGNIQGVGEGGE---VGVVGEVEGVGEVEE-VEELEEETAKEEPADF 574
E EGEG +G GEG E G E EG GE EE EE EEE EE +
Sbjct: 952 EGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEG 1011
Query: 575 PVEQPEE 581
E+ EE
Sbjct: 1012 EGEEEEE 1018
Score = 57.8 bits (138), Expect = 3e-08
Identities = 51/113 (45%), Positives = 63/113 (55%), Gaps = 5/113 (4%)
Query: 461 RYERFVKGENPFEIQDHSQDQQIEGDEEDEE-KIDEPIEEEEDEDEEEEAEEVGEVEEVE 519
R E +GE E + ++++ EG+EE+ E K +E EE E E+E EE E GE EE E
Sbjct: 826 REEEEEEGEGEEE-EGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGE 884
Query: 520 -EVEEVREG-GIEGEGNIQGVGEGGEVGVVGEVEGVGEVEEVEELEEETAKEE 570
E EE EG G E EG +G EG G E EG GE EE EE E E +EE
Sbjct: 885 GEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGE-EEGEEGEGEGEEEE 936
Score = 56.2 bits (134), Expect = 8e-08
Identities = 48/131 (36%), Positives = 65/131 (49%), Gaps = 28/131 (21%)
Query: 475 QDHSQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREG------- 527
++ +Q+ + G+EE E +E + EE+E++E E +E GE EEVE E EG
Sbjct: 721 KERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEER 780
Query: 528 ----------GIEGEG---NIQGVGEGGEVGVVGEVEGVGEVEE-----VEELEEETAKE 569
G +GEG +G GE E G GEVEG GEVEE EE EE +E
Sbjct: 781 AGKEEKGEEEGDQGEGEEEETEGRGEEKEEG--GEVEG-GEVEEGKGEREEEEEEGEGEE 837
Query: 570 EPADFPVEQPE 580
E + E+ E
Sbjct: 838 EEGEGEEEEGE 848
Score = 56.2 bits (134), Expect = 8e-08
Identities = 52/120 (43%), Positives = 60/120 (50%), Gaps = 21/120 (17%)
Query: 467 KGENPFEIQDHSQDQQIEGDEEDEEKIDEPIEEE--------EDEDEEEEAEEVGEVEEV 518
+GE E + ++ + +G+EE EE E EEE E E EEEE E GE EE
Sbjct: 903 EGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEG 962
Query: 519 E-EVEEVREG-GIEGEGN---IQGVGEG--------GEVGVVGEVEGVGEVEEVEELEEE 565
E E EE EG G EGEG +G GEG GE GE EG GE EE EE E E
Sbjct: 963 EGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVE 1022
Score = 54.7 bits (130), Expect = 2e-07
Identities = 50/107 (46%), Positives = 59/107 (55%), Gaps = 5/107 (4%)
Query: 467 KGENPFEIQDHSQD-QQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVE-EVEEVEEV 524
KGE E + ++ ++ EG+ E+EE E EE E E EEEE E GE E E E EE
Sbjct: 857 KGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEE 916
Query: 525 REGGIEGEGNIQGVGEGGEVGVVGEVE-GVGEVEEVEELEEETAKEE 570
EG E EG +G GEG E GE E G GE EE EE E E +EE
Sbjct: 917 GEGKGEEEGE-EGEGEGEEEEGEGEGEDGEGEGEE-EEGEWEGEEEE 961
Score = 54.3 bits (129), Expect = 3e-07
Identities = 45/109 (41%), Positives = 59/109 (54%), Gaps = 7/109 (6%)
Query: 467 KGENPFEIQDHSQDQQIEGDEEDEEKIDEPI-EEEEDEDEEEEAEEVGEVEEVEEVEEVR 525
+GE E + +++ EG E + +++E E EE+E+E E EE GE EE E E
Sbjct: 793 QGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEE 852
Query: 526 EGGIEGEGNIQG-VGEGGEVGVVGEVEG---VGEVEEVEELEEETAKEE 570
EG EG+G +G GEG E G GE EG GE E EE E E +EE
Sbjct: 853 EG--EGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEE 899
Score = 54.3 bits (129), Expect = 3e-07
Identities = 47/114 (41%), Positives = 60/114 (52%), Gaps = 5/114 (4%)
Query: 469 ENPFEIQDHSQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVE-EVEEVREG 527
E E + + ++ EG+EE EE E EEE + + EEE E GE EE E E EE EG
Sbjct: 851 EEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEG 910
Query: 528 GIEGEGNIQGVGEGGEVGVVGEVEGVGEVEEVE-ELEEETAKEEPADFPVEQPE 580
EGE +G G+G E G GE EG E E E E E +EE ++ E+ E
Sbjct: 911 --EGEEE-EGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEE 961
Score = 53.9 bits (128), Expect = 4e-07
Identities = 40/123 (32%), Positives = 64/123 (52%), Gaps = 9/123 (7%)
Query: 459 KARYERFVKGENPFEIQDHSQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEV 518
K R E GE E+ + + ++ +G+E+++++ ++ ++E +++ EE EE E
Sbjct: 681 KGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEE 740
Query: 519 EEVEEVREGGIEGEGNIQGVGEGGEVGVVGEVEGVGEVEEVEELEEETA-KEEPADFPVE 577
EE + E EGEG +G GE EVEG E EE E +EE A KEE + +
Sbjct: 741 EEGDREEEEEKEGEGKEEGEGE--------EVEGEREKEEGERKKEERAGKEEKGEEEGD 792
Query: 578 QPE 580
Q E
Sbjct: 793 QGE 795
Score = 52.8 bits (125), Expect = 9e-07
Identities = 51/135 (37%), Positives = 64/135 (47%), Gaps = 19/135 (14%)
Query: 466 VKGENPFEIQDHSQDQQIEGDEEDEEKIDEPI-EEEEDEDEEEEAEEVGEVE-------- 516
V+GE E + ++++ +E+ EE+ D+ EEEE E EE EE GEVE
Sbjct: 764 VEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGK 823
Query: 517 -EVEEVEEVREG-GIEGEG--------NIQGVGEGGEVGVVGEVEGVGEVEEVEELEEET 566
E EE EE EG EGEG +G G+G E G GE E GE E E EEE
Sbjct: 824 GEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEG 883
Query: 567 AKEEPADFPVEQPEE 581
E + E EE
Sbjct: 884 EGEGEEEGEGEGEEE 898
Score = 50.4 bits (119), Expect = 4e-06
Identities = 42/113 (37%), Positives = 56/113 (49%), Gaps = 13/113 (11%)
Query: 463 ERFVKGENPFEIQDHSQDQQIEGDEEDEEKI---------DEPIEEEEDEDEEEEAEEVG 513
+R + E E ++ + +++EG+ E EE +E EEE D+ E EE E G
Sbjct: 744 DREEEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEG 803
Query: 514 EVEEVEEVEEVREGGIE-GEGNIQGVGEGGEVGVVGEVEGVGEVEEVEELEEE 565
EE EE EV G +E G+G + E GE E EG GE EE E EEE
Sbjct: 804 RGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGE---EEEGEGEEEEGEGEEEE 853
Score = 49.3 bits (116), Expect = 1e-05
Identities = 47/106 (44%), Positives = 58/106 (54%), Gaps = 8/106 (7%)
Query: 467 KGENPFEIQDHSQDQQIEGDEEDEEKIDEPIEEEEDEDE-EEEAEEVGEVEEVEEVEEVR 525
+GE E + + ++ EG+ E EE+ + EEEE E E EEE E GE EE E E
Sbjct: 866 EGEEEGE-EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGE-- 922
Query: 526 EGGIEGEGNIQGVGEGGEVGVVGEVEGVGEVEEVE-ELEEETAKEE 570
E G EGEG +G E GE G + EG GE EE E E EEE + E
Sbjct: 923 EEGEEGEG--EGEEEEGE-GEGEDGEGEGEEEEGEWEGEEEEGEGE 965
Score = 46.6 bits (109), Expect = 6e-05
Identities = 45/126 (35%), Positives = 58/126 (46%), Gaps = 28/126 (22%)
Query: 473 EIQDHSQDQQIEGDEEDEEKIDEPIEEEEDEDEEE------------EAEEVGEVEEVEE 520
E + ++++ EG+ E+E + + EE E E EEE + EE GE E E
Sbjct: 873 EGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEG 932
Query: 521 VEEVREG-GIEGEG------------NIQGVGEGGEVGVVGEVEGVGEVEEVE---ELEE 564
EE EG G +GEG +G GEG E G EG GE EE E E EE
Sbjct: 933 EEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEE 992
Query: 565 ETAKEE 570
E +EE
Sbjct: 993 EEGEEE 998
Score = 41.2 bits (95), Expect = 0.003
Identities = 25/65 (38%), Positives = 36/65 (55%), Gaps = 1/65 (1%)
Query: 466 VKGENPFEIQDHSQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVR 525
V+GE E + + ++ EG+EE EE+ E EE + EEE EE G+ +E E E R
Sbjct: 1021 VEGEVEGE-EGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENER 1079
Query: 526 EGGIE 530
+ G E
Sbjct: 1080 QDGEE 1084
Score = 30.8 bits (68), Expect = 3.6
Identities = 31/112 (27%), Positives = 47/112 (41%), Gaps = 21/112 (18%)
Query: 490 EEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGGIE---------------GEGN 534
+E+++ P E+E ED + E EVE EE +V G E EG
Sbjct: 581 DEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDKAEVSEGK 640
Query: 535 IQGVGEGGEVGVVGEVEGVGE-----VEEVEELEEETAKEEPADFPVEQPEE 581
+ VGE E G G +G E E ++ E E +++ +E+P E
Sbjct: 641 AKSVGE-AEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGE 691
Score = 29.6 bits (65), Expect = 8.0
Identities = 16/52 (30%), Positives = 31/52 (59%), Gaps = 1/52 (1%)
Query: 473 EIQDHSQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEV 524
E ++ ++++ EG+ E+ + E EEEE+ +E EE E ++ EE ++V
Sbjct: 1038 EGEEEGEEREKEGEGEENRRNREE-EEEEEGKYQETGEEENERQDGEEYKKV 1088
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 60.5 bits (145), Expect = 4e-09
Identities = 47/135 (34%), Positives = 67/135 (49%), Gaps = 18/135 (13%)
Query: 466 VKGENPFEIQDHSQDQQIEGDEEDEEKIDEPIEEE----EDEDEEEEAEEVGEV---EEV 518
+K E E ++ ++++ EG+ E+EE+ E EEE E+ EEEE EE G+V EE
Sbjct: 401 LKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEE 460
Query: 519 EEVEEVREGGIEGEGNIQGVGE-GGEVGVVGEVEGV----------GEVEEVEELEEETA 567
EE EE G+E E QGV E GG G G E GE + + EE+
Sbjct: 461 EEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDE 520
Query: 568 KEEPADFPVEQPEEN 582
+E+ D + EE+
Sbjct: 521 EEDDEDEDDDDDEED 535
Score = 48.5 bits (114), Expect = 2e-05
Identities = 32/73 (43%), Positives = 41/73 (56%), Gaps = 6/73 (8%)
Query: 493 IDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGGIEGEGNIQGVGEGGEVGVVGEVEG 552
I ++ E +E+EEEE EE E E EE EE EGE + GEG E+G EVE
Sbjct: 397 ITTSLKSEGEEEEEEEEEEEEEEGEGEEEEE------EGEEEEEEGGEGEELGEEEEVEE 450
Query: 553 VGEVEEVEELEEE 565
G+V+ EE EE+
Sbjct: 451 EGDVDSDEEEEED 463
Score = 35.0 bits (79), Expect = 0.19
Identities = 14/34 (41%), Positives = 26/34 (76%), Gaps = 2/34 (5%)
Query: 479 QDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEV 512
+D + +EED+E+ D+ E+E+D+D+EE+ +EV
Sbjct: 508 EDSDSDSEEEDDEEEDD--EDEDDDDDEEDGDEV 539
Score = 31.2 bits (69), Expect = 2.7
Identities = 12/32 (37%), Positives = 22/32 (68%)
Query: 484 EGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEV 515
E + D E+ D+ E++EDED++++ E+ EV
Sbjct: 508 EDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEV 539
Score = 30.4 bits (67), Expect = 4.7
Identities = 11/36 (30%), Positives = 25/36 (69%)
Query: 483 IEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEV 518
+EG E+ + +E +EEED+++E++ ++ + +EV
Sbjct: 504 LEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEV 539
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 60.1 bits (144), Expect = 6e-09
Identities = 59/212 (27%), Positives = 82/212 (38%), Gaps = 13/212 (6%)
Query: 7 YTHSACRNTYQGFNGMDRDYGPGSYG-GMDRDYGHGSYGGQRSMDSYLNQSYGMDNH-SG 64
++ + +++ G +G + G G +G G + G G YG S QS G H SG
Sbjct: 621 HSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYG------SGSGQSSGFGQHVSG 674
Query: 65 GGGGSRFGPYESYDSRSSLGGRDL---YRSGYGFNEPEQSRFGGSYGGRFESSYRNSLDS 121
G S FG +ES SS G SGYG + + G S +S
Sbjct: 675 SGQSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQ 734
Query: 122 FGGRNQGGSSWEAPYSRSKLRPGFMEDRGRENYSSYSSFSSPHMKPAPVGSRG-RGTPAY 180
G + S + S S GF + R SSY SS + + G G R T +
Sbjct: 735 HGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGF 794
Query: 181 PESTFGSRNYDAFGGPSTGRGRGRGHMGDFGS 212
+ GS FG +G G+ G G GS
Sbjct: 795 GQHGSGSSQSTGFGQYGSGSGQSAG-FGQHGS 825
Score = 56.2 bits (134), Expect = 8e-08
Identities = 62/228 (27%), Positives = 89/228 (39%), Gaps = 22/228 (9%)
Query: 3 FEDDYTHSACRNTYQGFNGMDRDYGPGSYG---GMDRDYGH-----GSYGGQRSMDSYLN 54
F + S+ N Q +G + G G +G G +G G Y G S +
Sbjct: 987 FGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSD 1046
Query: 55 QSYGMDNH-SGGGGGSRFGPYESYDSRSSL---GGRDLYRSGY---GFNEPEQSRFGGSY 107
QS G H +G G S FG YES +SS G SGY G N + S FG
Sbjct: 1047 QSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHR 1106
Query: 108 GGRFESSYRNSLDSFGGRNQGGSSWEAPYSRSKLRPGFMEDRGRENYSSYSSFSSPHMKP 167
G +SS S G++ G + +S GF + R SSY + +
Sbjct: 1107 PGSGQSSGFGQYGSGSGQSSGFGQHGSGTGKSS---GFAQHEYRSGQSSYGQHGTGSSQS 1163
Query: 168 APVGSRGRG---TPAYPESTFGSRNYDAFGGPSTGRGRGRGHMGDFGS 212
+ G G T ++ + GS N+ + G + G+ G G +GS
Sbjct: 1164 SGCGQHESGSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTG-FGQYGS 1210
Score = 54.7 bits (130), Expect = 2e-07
Identities = 55/219 (25%), Positives = 80/219 (36%), Gaps = 33/219 (15%)
Query: 18 GFNGMDRDYGPGSYG----GMDRDYGHGSYG---------GQRSMDSYLNQSYGM----- 59
GF + G SYG G + G+G +G GQ + S + S+G
Sbjct: 680 GFGQHESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGS 739
Query: 60 -------DNHSGGGGGSRFGPYESYDSRSSLGGRDL---YRSGYGFNEPEQSRFGGSYGG 109
+ SG G S FG +ES +SS G SGYG + Q+ G +G
Sbjct: 740 GQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGS 799
Query: 110 RFESSYRNSLDSFGGRNQGGSSWEAPYSRSKLRPGFMEDRGRENYSSYSSFSSPHMKPAP 169
SS +G + + + S S GF + R + SSY S + +
Sbjct: 800 G--SSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSG 857
Query: 170 VGSRGRG---TPAYPESTFGSRNYDAFGGPSTGRGRGRG 205
G G T + + S Y FG +G G+ G
Sbjct: 858 YGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSGSGQSSG 896
Score = 43.5 bits (101), Expect = 5e-04
Identities = 66/240 (27%), Positives = 89/240 (37%), Gaps = 36/240 (15%)
Query: 9 HSACRNTYQGF----NGMDRDYGPGSYG---------GMDRDYGHGSYGGQRSMDSYLNQ 55
H + Y GF +G + G G +G G H S GQ S +
Sbjct: 874 HRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSS 933
Query: 56 SYGMDNHSGGGGGSRFGPYESYDSRSSLGGRDLYRSGY--GFNEPEQSRFGGSYGGRFES 113
YG S G FG + S +SS G+ SG GF + E S G+ ES
Sbjct: 934 GYGQHG-SSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHES 992
Query: 114 SYRNSLDSFGGRNQGGSSWEAPY----SRSKLRPGFMEDRGRE-NYSSYSSFSSPHMKPA 168
R+S ++ G++ GSS + Y S S GF + R YS + S + +
Sbjct: 993 --RSSQSNY-GQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSS 1049
Query: 169 PVGSRGRGTP-----AYPESTFGSRNYDAFG-GPSTGRGRGR-----GHMGDFGSIHRPG 217
G G G+ ES +Y G G S G G+ G FG HRPG
Sbjct: 1050 GFGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQ-HRPG 1108
Score = 38.1 bits (87), Expect = 0.022
Identities = 53/226 (23%), Positives = 72/226 (31%), Gaps = 28/226 (12%)
Query: 18 GFNGMDRDYGPGSYGGMDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGGGGSRFGPYESY 77
GF G S G H S GQ S + YG S G S FG + S
Sbjct: 819 GFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHG-SSSGQTSGFGQHRSS 877
Query: 78 DSRSSLGGRDLYRSGYGFNEPEQSRFGGSYGGRFESSYRNSLDSFG----------GRNQ 127
+ S G+ SG + G Y G + R+ S+G G Q
Sbjct: 878 SGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQ 937
Query: 128 GGSSWEAPYSRSKLRPGFMEDRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAYPESTFGS 187
GSS + + R G + G + S S SS + + G + ES
Sbjct: 938 HGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQH-ESRSSQ 996
Query: 188 RNYDAFG----------------GPSTGRGRGRGHMGDFGSIHRPG 217
NY G G +TG G+ R G + + G
Sbjct: 997 SNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHG 1042
Score = 37.4 bits (85), Expect = 0.038
Identities = 62/222 (27%), Positives = 78/222 (35%), Gaps = 57/222 (25%)
Query: 39 GHGSYGGQRSMDSYLNQSYGMDNH--------------SGGGGGSRFGPYESYDSRSSLG 84
G G GQ S +QS G D H SG G S FG S +SS
Sbjct: 448 GSGQTCGQHESTS--SQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGF 505
Query: 85 GRDLYRSGY---------------GFNEPE----QSRFG------------GSYGGRFES 113
G+ SG GF + E QS +G G YG R S
Sbjct: 506 GQHGSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETS 565
Query: 114 SY-RNSLDS-----FG--GRNQGGSSWEAPY-SRSKLRPGFMEDRGRENYSSYSSFSSPH 164
+ ++ L S FG G G SS + S S GF + R SSY SS
Sbjct: 566 GFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGS 625
Query: 165 MKPAPVGSRG-RGTPAYPESTFGSRNYDAFGGPSTGRGRGRG 205
+ + G G R T + + GS FG +G G+ G
Sbjct: 626 SQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSG 667
Score = 29.6 bits (65), Expect = 8.0
Identities = 17/57 (29%), Positives = 28/57 (49%), Gaps = 3/57 (5%)
Query: 8 THSACRNTYQGFNGMDRDYGPGSYGGMDRDYGHGSY---GGQRSMDSYLNQSYGMDN 61
+H ++ + +G + + GSYG + DYGH Y GG R S + S+ D+
Sbjct: 2326 SHFQSHSSERQRHGSSQVWKHGSYGPAEYDYGHTGYGPSGGSRKSISNSHLSWSTDS 2382
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 59.3 bits (142), Expect = 9e-09
Identities = 42/97 (43%), Positives = 55/97 (56%), Gaps = 6/97 (6%)
Query: 474 IQDHSQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGGIEGEG 533
I +S D++ E +EE+EE+ +E EEEED +EEEE EE EE EE EE E E EG
Sbjct: 881 ININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEG 940
Query: 534 NIQGVGEGGEVGVVGEVEGVGEVEEVEELEEETAKEE 570
++ E + E E+EEVE+LE TA E
Sbjct: 941 ELE------EEEEEEDEEEEEELEEVEDLEFGTAGGE 971
Score = 55.5 bits (132), Expect = 1e-07
Identities = 29/69 (42%), Positives = 44/69 (63%), Gaps = 4/69 (5%)
Query: 469 ENPFEIQDHSQDQQIEGDEEDEEKIDEPIEEEE----DEDEEEEAEEVGEVEEVEEVEEV 524
E FE ++ +++ E +EE+EE+ +E EEEE +E+EEE+ EE E+EEVE++E
Sbjct: 907 EEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFG 966
Query: 525 REGGIEGEG 533
GG EG
Sbjct: 967 TAGGEVEEG 975
Score = 55.1 bits (131), Expect = 2e-07
Identities = 37/105 (35%), Positives = 55/105 (52%)
Query: 475 QDHSQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGGIEGEGN 534
++ ++++ E +EE+EE+ +E EEEE+++EE EE E EE EE E EG +E E
Sbjct: 888 EEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEE 947
Query: 535 IQGVGEGGEVGVVGEVEGVGEVEEVEELEEETAKEEPADFPVEQP 579
+ E E+ V ++E EVEE PA P E P
Sbjct: 948 EEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESP 992
Score = 54.3 bits (129), Expect = 3e-07
Identities = 38/90 (42%), Positives = 50/90 (55%), Gaps = 11/90 (12%)
Query: 469 ENPFEIQDHSQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGG 528
E E ++ +++ E +EEDEE+ E EEEE+E EEE EE GE+EE EE E+ E
Sbjct: 896 EEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEE-- 953
Query: 529 IEGEGNIQGVGEGGEVGVVGEVEGVGEVEE 558
E ++ V E E G G GEVEE
Sbjct: 954 ---EEELEEV-EDLEFGTAG-----GEVEE 974
Score = 51.2 bits (121), Expect = 3e-06
Identities = 36/97 (37%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
Query: 468 GENPFEIQDHSQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREG 527
G P +++ I +E+EE+ +E EEEE+E+EEEE E E +E E EE E
Sbjct: 868 GGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEE 927
Query: 528 GIEGEGNIQGVGEGGEVGVVGEVEGVGEVEEVEELEE 564
E E + E GE+ E E E EE+EE+E+
Sbjct: 928 EEEFEEEFE--EEEGELEEEEEEEDEEEEEELEEVED 962
Score = 43.1 bits (100), Expect = 7e-04
Identities = 35/97 (36%), Positives = 43/97 (44%), Gaps = 33/97 (34%)
Query: 486 DEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGGIEGEGNIQGVGEGGEVG 545
DEE+EE EEEE+E+EEEE EE + EE EE EE
Sbjct: 887 DEEEEE------EEEEEEEEEEEEEEEEDFEEEEEDEE---------------------- 918
Query: 546 VVGEVEGVGEVEEVEELEEETAKEEPADFPVEQPEEN 582
E E EE EE EE +EE + E+ EE+
Sbjct: 919 -----EYFEEEEEEEEEFEEEFEEEEGELEEEEEEED 950
Score = 39.7 bits (91), Expect = 0.008
Identities = 25/65 (38%), Positives = 36/65 (55%), Gaps = 7/65 (10%)
Query: 463 ERFVKGENPFEIQDHSQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVE 522
E + + E E + + ++ EG+ E+E EEEEDE+EEEE EEV ++E
Sbjct: 918 EEYFEEEEEEEEEFEEEFEEEEGELEEE-------EEEEDEEEEEELEEVEDLEFGTAGG 970
Query: 523 EVREG 527
EV EG
Sbjct: 971 EVEEG 975
Score = 29.6 bits (65), Expect = 8.0
Identities = 13/49 (26%), Positives = 26/49 (53%)
Query: 256 PKLAKPMEKISLSKSPTKTDPKNEEEEKRRIEARREKQRRRREKNSEKY 304
P L + + I+++ S + + + EEEE+ E E+ E++ E+Y
Sbjct: 872 PALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEY 920
>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
Length = 589
Score = 56.2 bits (134), Expect = 8e-08
Identities = 65/221 (29%), Positives = 76/221 (34%), Gaps = 44/221 (19%)
Query: 16 YQGFNGMDRDYGPGSYGGMDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGGGGSRFGPYE 75
Y+G G D G YGG D G YGG RS Y D GG GG R G
Sbjct: 402 YRGRGGRGGDRG--GYGG---DRSGGGYGGDRSSGG----GYSGDRSGGGYGGDRSGGGY 452
Query: 76 SYDSRSSLGGRDLYRSGYGFNEPEQSRFG---GSYGGRFESSYRNSLDSFGGRNQGGSSW 132
D GG G G+ +G G YGG Y +GG G
Sbjct: 453 GGDRGGGYGG----DRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGD 508
Query: 133 EAPYSRSKLRPGFMEDRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRNYDA 192
Y R G+ DR R Y G RG G S +G
Sbjct: 509 RGGYGGD--RGGYGGDRSRGGYG---------------GDRGGG------SGYGGDRSGG 545
Query: 193 FGGPSTGRG----RGRGHMGDFGSI-HRPGIVVDYQNKSTN 228
+GG +G G RG G+ GD G + G DY+N N
Sbjct: 546 YGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRNDYRNDQRN 586
Score = 39.3 bits (90), Expect = 0.010
Identities = 54/198 (27%), Positives = 71/198 (35%), Gaps = 47/198 (23%)
Query: 18 GFNGMDRDYGPGSYGGMDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGGG--GSRFGPYE 75
GF G D G + + G+ ++ + S + N+ D+ GG G +G
Sbjct: 342 GFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQ-CNEPRPEDSRPSGGDFRGRGYGGER 400
Query: 76 SYDSRSSLGGRDLYRSGYGFNEPEQSRFGGSYGGRFESSYRNSLDSFGGRNQGGSSWEAP 135
Y R GGR R GYG R GG YGG R+S + G GG
Sbjct: 401 GYRGR---GGRGGDRGGYG-----GDRSGGGYGGD-----RSSGGGYSGDRSGGG----- 442
Query: 136 YSRSKLRPGFMEDRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRNYDAFGG 195
Y + G+ DRG Y G RG G +G +GG
Sbjct: 443 YGGDRSGGGYGGDRG----GGYG------------GDRGGG--------YGGDRGGGYGG 478
Query: 196 PSTGRG--RGRGHMGDFG 211
G G RG G+ GD G
Sbjct: 479 DRGGYGGDRGGGYGGDRG 496
Score = 36.6 bits (83), Expect = 0.065
Identities = 68/284 (23%), Positives = 94/284 (33%), Gaps = 68/284 (23%)
Query: 60 DNHSGGGGGSRFGPYESYDSRSSLGGRDLYRSGYGFNEPEQSRFGGSYGGRFESSYRNSL 119
D+ S G G Y +Y + S G +S G+ + S +G +Y G SSY S
Sbjct: 3 DSGSYGQSGGEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSG--YSSYGQSY 60
Query: 120 -DSFGG-RNQGGSSW-EAPY-------------SRSKLRPGFME---------------D 148
S+GG NQ SS+ + PY S+ P + + D
Sbjct: 61 SQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYD 120
Query: 149 RGRENYSSYSSFSSPHMKPA----------------------PVGSRGRGTPAYPESTFG 186
+ + +Y S++ H + V G Y S G
Sbjct: 121 QHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHTQDDRRDVSRYGEDNRGYGGSQGG 180
Query: 187 SR---NYDAFG-GPSTGRGRG-RGHMGDFGSIHRPGIVVDYQNKSTN------VTVAAAR 235
R YD G GP TG G RG +FG G D ++S N
Sbjct: 181 GRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADSESDNSDNNTIFVQGLGE 240
Query: 236 GIKRKMMQPFNKPSGTFIKKPKLAKPMEKISLSKSPTKTDPKNE 279
G+ + F K G K KPM + K K PK E
Sbjct: 241 GVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGK--PKGE 282
Score = 32.0 bits (71), Expect = 1.6
Identities = 27/85 (31%), Positives = 31/85 (36%), Gaps = 21/85 (24%)
Query: 7 YTHSACRNTYQGFNGMDRDYGPGSYGGMDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGG 66
Y R Y G G YG GG D G YGG R GG
Sbjct: 519 YGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDR---------------GGGY 563
Query: 67 GGSRFGPYESYDSRSSLGGRDLYRS 91
GG R G Y + +GGR+ YR+
Sbjct: 564 GGDRGG----YGGK--MGGRNDYRN 582
Score = 29.6 bits (65), Expect = 8.0
Identities = 37/132 (28%), Positives = 49/132 (37%), Gaps = 15/132 (11%)
Query: 87 DLYRSGYGFNEPEQSRFGGSYGGRFESSYRNSLDSFGGRNQGGSSWEAPYSRSKLRPGFM 146
++ + + PE R GGS GGR F GR GG P S + P
Sbjct: 308 NIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGR--GGD----PKSGDWVCPN-- 359
Query: 147 EDRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRNYDAFGGPSTGRG----- 201
G N++ +S + + +P P SR G G R Y GG RG
Sbjct: 360 PSCGNMNFARRNSCNQCN-EPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGD 418
Query: 202 -RGRGHMGDFGS 212
G G+ GD S
Sbjct: 419 RSGGGYGGDRSS 430
>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
Length = 592
Score = 56.2 bits (134), Expect = 8e-08
Identities = 65/221 (29%), Positives = 76/221 (34%), Gaps = 44/221 (19%)
Query: 16 YQGFNGMDRDYGPGSYGGMDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGGGGSRFGPYE 75
Y+G G D G YGG D G YGG RS Y D GG GG R G
Sbjct: 405 YRGRGGRGGDRG--GYGG---DRSGGGYGGDRSSGG----GYSGDRSGGGYGGDRSGGGY 455
Query: 76 SYDSRSSLGGRDLYRSGYGFNEPEQSRFG---GSYGGRFESSYRNSLDSFGGRNQGGSSW 132
D GG G G+ +G G YGG Y +GG G
Sbjct: 456 GGDRGGGYGG----DRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGD 511
Query: 133 EAPYSRSKLRPGFMEDRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRNYDA 192
Y R G+ DR R Y G RG G S +G
Sbjct: 512 RGGYGGD--RGGYGGDRSRGGYG---------------GDRGGG------SGYGGDRSGG 548
Query: 193 FGGPSTGRG----RGRGHMGDFGSI-HRPGIVVDYQNKSTN 228
+GG +G G RG G+ GD G + G DY+N N
Sbjct: 549 YGGDRSGGGYGGDRGGGYGGDRGGYGGKMGGRNDYRNDQRN 589
Score = 40.0 bits (92), Expect = 0.006
Identities = 73/301 (24%), Positives = 103/301 (34%), Gaps = 70/301 (23%)
Query: 29 GSYGGMDRDYGHGSYGGQRSMDSYLN---QSYGMDNHSGGGGGSRFGPYESYDSRSSLGG 85
GSYG S G Q+S +Y N Q YG + S G G + SS G
Sbjct: 5 GSYGQ--------SGGEQQSYSTYGNPGSQGYGQASQSYSGYGQT--------TDSSYGQ 48
Query: 86 RDLYRSGYGFNEPEQSRFGGSYGGRFESSY----------RNSLDSFGGRNQGGSSWEAP 135
S YG ++ S+ G Y + +SSY + +++S G + S++ P
Sbjct: 49 NYSGYSSYGQSQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQP 108
Query: 136 -YSRS---KLRPGFMEDRG-------------------------RENYSSYSSFSSPHMK 166
Y + + G+ + +G RENYS ++
Sbjct: 109 DYGQQDSYDQQSGYDQHQGSYDEQSNYDQQHDSYSQNQQSYHSQRENYSHHT--QDDRRD 166
Query: 167 PAPVGSRGRGTPAYPESTFGSRNYDAFG-GPSTGRGRG-RGHMGDFGSIHRPGIVVDYQN 224
+ G RG G YD G GP TG G RG +FG G D +
Sbjct: 167 VSRYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDADS 226
Query: 225 KSTN------VTVAAARGIKRKMMQPFNKPSGTFIKKPKLAKPMEKISLSKSPTKTDPKN 278
+S N G+ + F K G K KPM + K K PK
Sbjct: 227 ESDNSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGK--PKG 284
Query: 279 E 279
E
Sbjct: 285 E 285
Score = 39.3 bits (90), Expect = 0.010
Identities = 54/198 (27%), Positives = 71/198 (35%), Gaps = 47/198 (23%)
Query: 18 GFNGMDRDYGPGSYGGMDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGGG--GSRFGPYE 75
GF G D G + + G+ ++ + S + N+ D+ GG G +G
Sbjct: 345 GFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQ-CNEPRPEDSRPSGGDFRGRGYGGER 403
Query: 76 SYDSRSSLGGRDLYRSGYGFNEPEQSRFGGSYGGRFESSYRNSLDSFGGRNQGGSSWEAP 135
Y R GGR R GYG R GG YGG R+S + G GG
Sbjct: 404 GYRGR---GGRGGDRGGYG-----GDRSGGGYGGD-----RSSGGGYSGDRSGGG----- 445
Query: 136 YSRSKLRPGFMEDRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRNYDAFGG 195
Y + G+ DRG Y G RG G +G +GG
Sbjct: 446 YGGDRSGGGYGGDRG----GGYG------------GDRGGG--------YGGDRGGGYGG 481
Query: 196 PSTGRG--RGRGHMGDFG 211
G G RG G+ GD G
Sbjct: 482 DRGGYGGDRGGGYGGDRG 499
Score = 32.0 bits (71), Expect = 1.6
Identities = 27/85 (31%), Positives = 31/85 (36%), Gaps = 21/85 (24%)
Query: 7 YTHSACRNTYQGFNGMDRDYGPGSYGGMDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGG 66
Y R Y G G YG GG D G YGG R GG
Sbjct: 522 YGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDR---------------GGGY 566
Query: 67 GGSRFGPYESYDSRSSLGGRDLYRS 91
GG R G Y + +GGR+ YR+
Sbjct: 567 GGDRGG----YGGK--MGGRNDYRN 585
Score = 29.6 bits (65), Expect = 8.0
Identities = 37/132 (28%), Positives = 49/132 (37%), Gaps = 15/132 (11%)
Query: 87 DLYRSGYGFNEPEQSRFGGSYGGRFESSYRNSLDSFGGRNQGGSSWEAPYSRSKLRPGFM 146
++ + + PE R GGS GGR F GR GG P S + P
Sbjct: 311 NIIKVSFATRRPEFMRGGGSGGGRRGRGGYRGRGGFQGR--GGD----PKSGDWVCPN-- 362
Query: 147 EDRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRNYDAFGGPSTGRG----- 201
G N++ +S + + +P P SR G G R Y GG RG
Sbjct: 363 PSCGNMNFARRNSCNQCN-EPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGD 421
Query: 202 -RGRGHMGDFGS 212
G G+ GD S
Sbjct: 422 RSGGGYGGDRSS 433
>gi|58761548 tau tubulin kinase 1 [Homo sapiens]
Length = 1321
Score = 56.2 bits (134), Expect = 8e-08
Identities = 39/105 (37%), Positives = 50/105 (47%), Gaps = 6/105 (5%)
Query: 482 QIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGGIEGEGNIQG---- 537
Q G EE+EE+ ++ EEEEDE+EEEE EE E EE EE EE G + G
Sbjct: 728 QANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSG 787
Query: 538 -VGEGGEVGVVGEVEGVGEVEEVEELEEETAKEEPADFPVEQPEE 581
EG E EG ++ +E + AD +E PEE
Sbjct: 788 SSSEGSERSTDRSQEGAPSTLLADDQKESRGRASMADGDLE-PEE 831
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 55.1 bits (131), Expect = 2e-07
Identities = 28/53 (52%), Positives = 36/53 (67%)
Query: 474 IQDHSQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVRE 526
I H ++ + E +EE+EE+ DE EEEE+E+EEEE EE E EE EE EE E
Sbjct: 254 ILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 306
Score = 52.8 bits (125), Expect = 9e-07
Identities = 27/54 (50%), Positives = 37/54 (68%)
Query: 467 KGENPFEIQDHSQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEE 520
KG E +D ++++ E +EEDEE+ +E EEEE+E+EEEE EE E EE EE
Sbjct: 252 KGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 305
Score = 50.8 bits (120), Expect = 3e-06
Identities = 28/47 (59%), Positives = 32/47 (68%)
Query: 486 DEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGGIEGE 532
+EEDEE+ +E EEEEDE+EEEE EE E EE EE EE E E E
Sbjct: 258 EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 304
Score = 47.4 bits (111), Expect = 4e-05
Identities = 26/58 (44%), Positives = 37/58 (63%)
Query: 475 QDHSQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGGIEGE 532
++ S+ + I EE++E+ +E EEEE+++EEEE EE E EE EE EE E E E
Sbjct: 246 EESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 303
Score = 46.6 bits (109), Expect = 6e-05
Identities = 25/49 (51%), Positives = 33/49 (67%)
Query: 484 EGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGGIEGE 532
E ++E+EE+ +E EE+E+E+EEEE EE E EE EE EE E E E
Sbjct: 258 EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 306
Score = 44.3 bits (103), Expect = 3e-04
Identities = 29/105 (27%), Positives = 50/105 (47%), Gaps = 3/105 (2%)
Query: 469 ENPFEIQDHSQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGG 528
E E ++ ++ + E +EE+EE+ +E EEEE+E+EEEE EE +V E+
Sbjct: 262 EEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTS 321
Query: 529 IEGEGNIQGVGEGG---EVGVVGEVEGVGEVEEVEELEEETAKEE 570
+ ++G E V+ EV + +E + T +E
Sbjct: 322 AQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDE 366
Score = 39.7 bits (91), Expect = 0.008
Identities = 37/124 (29%), Positives = 50/124 (40%), Gaps = 40/124 (32%)
Query: 465 FVKGENPFEI----QDHSQD---QQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEE 517
F++ E+ E+ + SQD Q +E +E + I E+EDEEEE EE E E+
Sbjct: 215 FIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEED 274
Query: 518 VEEVEEVREGGIEGEGNIQGVGEGGEVGVVGEVEGVGEVEEVEELEEETAKEEPADFPVE 577
EE EE EE EE EEE +EE + E
Sbjct: 275 EEEEEE---------------------------------EEEEEEEEEEEEEEEEEEEEE 301
Query: 578 QPEE 581
+ EE
Sbjct: 302 EEEE 305
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 54.7 bits (130), Expect = 2e-07
Identities = 28/70 (40%), Positives = 45/70 (64%), Gaps = 1/70 (1%)
Query: 475 QDHSQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVE-EVREGGIEGEG 533
+D +D+++E D E++E++DE EEEE+E+EEEE EE E EE E+ E + +E G + +
Sbjct: 207 EDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDT 266
Query: 534 NIQGVGEGGE 543
+ G E
Sbjct: 267 RSEASDSGSE 276
Score = 47.4 bits (111), Expect = 4e-05
Identities = 27/59 (45%), Positives = 35/59 (59%), Gaps = 4/59 (6%)
Query: 478 SQDQQIEGDEEDEEKIDEPIEE----EEDEDEEEEAEEVGEVEEVEEVEEVREGGIEGE 532
S D+Q E +EE ++E +EE EED +E+EE +E GE EE EE EE E E E
Sbjct: 190 SSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEE 248
Score = 47.4 bits (111), Expect = 4e-05
Identities = 25/57 (43%), Positives = 34/57 (59%)
Query: 470 NPFEIQDHSQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVRE 526
N E ++ ++ +E DEE EE +E E +ED +EEEE EE E EE EE EE +
Sbjct: 196 NNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQ 252
Score = 42.0 bits (97), Expect = 0.002
Identities = 21/62 (33%), Positives = 38/62 (61%), Gaps = 1/62 (1%)
Query: 475 QDHSQDQQIEGD-EEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGGIEGEG 533
+D +D++++ D EE+EE+ +E EEEE+E+EE E +E + EE + + E G
Sbjct: 217 EDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSE 276
Query: 534 NI 535
++
Sbjct: 277 SV 278
Score = 40.0 bits (92), Expect = 0.006
Identities = 21/68 (30%), Positives = 35/68 (51%)
Query: 475 QDHSQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGGIEGEGN 534
+D D+ E +EE+EE+ +E EEEE+E E++E ++ E + + E + G E
Sbjct: 221 EDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSF 280
Query: 535 IQGVGEGG 542
G G
Sbjct: 281 TDGSVRSG 288
Score = 39.7 bits (91), Expect = 0.008
Identities = 32/105 (30%), Positives = 45/105 (42%), Gaps = 17/105 (16%)
Query: 478 SQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGGIEGEGNIQG 537
S +++ +E + +++ E EE G E+VEE EEV E E E
Sbjct: 169 SSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDE----- 223
Query: 538 VGEGGEVGVVGEVEGVGEVEEVEELEEETAKEEPADFPVEQPEEN 582
EV+ GE EE EE EEE +EE + EQ E +
Sbjct: 224 -----------EVDEDGEEEEEEE-EEEEEEEEEEEEEYEQDERD 256
Score = 39.7 bits (91), Expect = 0.008
Identities = 35/106 (33%), Positives = 42/106 (39%), Gaps = 27/106 (25%)
Query: 476 DHSQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGGIEGEGNI 535
DH DE+ +E EED +E+EE E E+ EE EEV E G E E
Sbjct: 182 DHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVE-----EDAEEDEEVDEDGEEEE--- 233
Query: 536 QGVGEGGEVGVVGEVEGVGEVEEVEELEEETAKEEPADFPVEQPEE 581
E EE EE EEE +EE +Q EE
Sbjct: 234 -------------------EEEEEEEEEEEEEEEEYEQDERDQKEE 260
Score = 33.1 bits (74), Expect = 0.72
Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 6/97 (6%)
Query: 488 EDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGGIEGEGNIQGVGEGGEVGVV 547
+ E+I ++ + EEV E + E G + +GN E E GV
Sbjct: 150 DGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNT---ENEEEGVE 206
Query: 548 GEVEGVGEVEEVEELEEE---TAKEEPADFPVEQPEE 581
+VE EVEE E +EE +EE + E+ EE
Sbjct: 207 EDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEE 243
Score = 30.4 bits (67), Expect = 4.7
Identities = 25/92 (27%), Positives = 44/92 (47%), Gaps = 11/92 (11%)
Query: 221 DYQNKSTNVTVAAARGIKRKMM---QPF-NKPSGTFIKKPKLAKPMEKISLSKSPTKTDP 276
+YQ N + A R I+ +P+ N+P T ++K + E+ + S +P ++
Sbjct: 99 EYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRK----RDPERRAKSPTPDGSER 154
Query: 277 KNEEEEKRRIEARREKQRRRREKNSEKYGDGY 308
E ++R A R Q + E NSE+YG +
Sbjct: 155 IGLEVDRR---ASRSSQSSKEEVNSEEYGSDH 183
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 54.7 bits (130), Expect = 2e-07
Identities = 28/70 (40%), Positives = 45/70 (64%), Gaps = 1/70 (1%)
Query: 475 QDHSQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVE-EVREGGIEGEG 533
+D +D+++E D E++E++DE EEEE+E+EEEE EE E EE E+ E + +E G + +
Sbjct: 207 EDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDT 266
Query: 534 NIQGVGEGGE 543
+ G E
Sbjct: 267 RSEASDSGSE 276
Score = 47.4 bits (111), Expect = 4e-05
Identities = 27/59 (45%), Positives = 35/59 (59%), Gaps = 4/59 (6%)
Query: 478 SQDQQIEGDEEDEEKIDEPIEE----EEDEDEEEEAEEVGEVEEVEEVEEVREGGIEGE 532
S D+Q E +EE ++E +EE EED +E+EE +E GE EE EE EE E E E
Sbjct: 190 SSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEE 248
Score = 47.4 bits (111), Expect = 4e-05
Identities = 25/57 (43%), Positives = 34/57 (59%)
Query: 470 NPFEIQDHSQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVRE 526
N E ++ ++ +E DEE EE +E E +ED +EEEE EE E EE EE EE +
Sbjct: 196 NNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQ 252
Score = 42.0 bits (97), Expect = 0.002
Identities = 21/62 (33%), Positives = 38/62 (61%), Gaps = 1/62 (1%)
Query: 475 QDHSQDQQIEGD-EEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGGIEGEG 533
+D +D++++ D EE+EE+ +E EEEE+E+EE E +E + EE + + E G
Sbjct: 217 EDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSE 276
Query: 534 NI 535
++
Sbjct: 277 SV 278
Score = 40.0 bits (92), Expect = 0.006
Identities = 21/68 (30%), Positives = 35/68 (51%)
Query: 475 QDHSQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGGIEGEGN 534
+D D+ E +EE+EE+ +E EEEE+E E++E ++ E + + E + G E
Sbjct: 221 EDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGSESVSF 280
Query: 535 IQGVGEGG 542
G G
Sbjct: 281 TDGSVRSG 288
Score = 39.7 bits (91), Expect = 0.008
Identities = 32/105 (30%), Positives = 45/105 (42%), Gaps = 17/105 (16%)
Query: 478 SQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGGIEGEGNIQG 537
S +++ +E + +++ E EE G E+VEE EEV E E E
Sbjct: 169 SSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDE----- 223
Query: 538 VGEGGEVGVVGEVEGVGEVEEVEELEEETAKEEPADFPVEQPEEN 582
EV+ GE EE EE EEE +EE + EQ E +
Sbjct: 224 -----------EVDEDGEEEEEEE-EEEEEEEEEEEEEYEQDERD 256
Score = 39.7 bits (91), Expect = 0.008
Identities = 35/106 (33%), Positives = 42/106 (39%), Gaps = 27/106 (25%)
Query: 476 DHSQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGGIEGEGNI 535
DH DE+ +E EED +E+EE E E+ EE EEV E G E E
Sbjct: 182 DHETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVE-----EDAEEDEEVDEDGEEEE--- 233
Query: 536 QGVGEGGEVGVVGEVEGVGEVEEVEELEEETAKEEPADFPVEQPEE 581
E EE EE EEE +EE +Q EE
Sbjct: 234 -------------------EEEEEEEEEEEEEEEEYEQDERDQKEE 260
Score = 33.1 bits (74), Expect = 0.72
Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 6/97 (6%)
Query: 488 EDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGGIEGEGNIQGVGEGGEVGVV 547
+ E+I ++ + EEV E + E G + +GN E E GV
Sbjct: 150 DGSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNT---ENEEEGVE 206
Query: 548 GEVEGVGEVEEVEELEEE---TAKEEPADFPVEQPEE 581
+VE EVEE E +EE +EE + E+ EE
Sbjct: 207 EDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEE 243
Score = 30.4 bits (67), Expect = 4.7
Identities = 25/92 (27%), Positives = 44/92 (47%), Gaps = 11/92 (11%)
Query: 221 DYQNKSTNVTVAAARGIKRKMM---QPF-NKPSGTFIKKPKLAKPMEKISLSKSPTKTDP 276
+YQ N + A R I+ +P+ N+P T ++K + E+ + S +P ++
Sbjct: 99 EYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRK----RDPERRAKSPTPDGSER 154
Query: 277 KNEEEEKRRIEARREKQRRRREKNSEKYGDGY 308
E ++R A R Q + E NSE+YG +
Sbjct: 155 IGLEVDRR---ASRSSQSSKEEVNSEEYGSDH 183
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 53.9 bits (128), Expect = 4e-07
Identities = 60/218 (27%), Positives = 87/218 (39%), Gaps = 33/218 (15%)
Query: 16 YQGFNGMDRDYGP-GSYGGMDRDYG-HGSYGGQRSMDSYLNQSYGMDNHSGGGGGSRFGP 73
++ +G Y GS G YG HGS GQ S G + S G SR+G
Sbjct: 2110 HESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSR--------GERHGSSSGSSSRYGQ 2161
Query: 74 YESYDSRSSLGGRDLYRSGYGFNEPEQSRFG------------GSYGGRFES----SYRN 117
+ S +SS GR SG+ P + R G GS GR S R+
Sbjct: 2162 HGSGSRQSSGHGRQGSGSGH---SPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRS 2218
Query: 118 SLDSFGGRNQGGSSWEAPYSRSKLRPGFMEDRGRENYSS--YSSFSSPHMKPAPVGSRGR 175
S G+++ GS + YS+ G +G+ +S S+F S G+
Sbjct: 2219 GHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQ 2278
Query: 176 -GTPAYPESTFGSRNYDAFGGPSTGR-GRGRGHMGDFG 211
G+ + S++G + + PS GR G G GH +G
Sbjct: 2279 HGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYG 2316
Score = 48.5 bits (114), Expect = 2e-05
Identities = 64/228 (28%), Positives = 81/228 (35%), Gaps = 27/228 (11%)
Query: 3 FEDDYTHSACRNTYQGFNGMDRDYGP-GSYGGMDRDYG-HGSYGGQRSMDSYLNQSYGMD 60
+E +HS+ + +G YG GS G +G HGS GQ S S G
Sbjct: 1510 YESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSS-------SCGQH 1562
Query: 61 NHSGGGGGSRFGPYESYDSRSSLGGRDLYRSGYGFNEPEQ---SRFGGSYGGRFESSYRN 117
S G S G + S S+SS GR SG ++ SR SYG S R+
Sbjct: 1563 GASSGQSSSH-GQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRS 1621
Query: 118 SLDSFGGRNQGGSSWEAPYSRSKLRPGFMEDRGR-----ENYSSYSSFSSPHMKPAPVGS 172
S G G SS + S + G Y + S S + GS
Sbjct: 1622 SSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGS 1681
Query: 173 RGRGTPAYPESTFGSRNYDAFG--------GPSTGR-GRGRGHMGDFG 211
R + Y + GSR G PS GR G G GH G
Sbjct: 1682 SSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHG 1729
Score = 48.1 bits (113), Expect = 2e-05
Identities = 66/229 (28%), Positives = 90/229 (39%), Gaps = 41/229 (17%)
Query: 8 THSACRNTYQGFN------GMDRDYGP-GSYGGMDRDYG-HGSYGGQRSMDSYLNQSYGM 59
TH + GF+ G Y GS G YG HGS GQ S G
Sbjct: 220 THGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSR--------GE 271
Query: 60 DNHSGGGGGSRFGPYESYDSRSSLG-GRD-----------LYRSGYGFNEPE-QSRFGGS 106
+ S G S +G + S SR SLG GR + SG G + Q G S
Sbjct: 272 RHRSSSGSSSSYGQHGS-GSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSS 330
Query: 107 YG---GRFESSYRNSLDSFGGRNQGGSSWEAPYSRSKLRPGFMEDRGRENYSSYSSFSSP 163
Y G +ES + S G+++ GS + YS+ G +G+ +S + SS
Sbjct: 331 YSYSRGHYESG--SGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSG 388
Query: 164 HMKPAPVGSRGRGTPAYPESTFGSRNYDAFGGPSTGRGRGRGHMGDFGS 212
GS R + +Y + SR+ G S+G G+ GH G GS
Sbjct: 389 QH-----GSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGH-GQRGS 431
Score = 45.1 bits (105), Expect = 2e-04
Identities = 62/224 (27%), Positives = 83/224 (37%), Gaps = 38/224 (16%)
Query: 20 NGMDRDYGPGSYGGMDRDYGHGSYG-----------GQRSMDSYLNQSYGMDNHSGGGGG 68
+G YG G + GHG +G G+ S + SYG SG G
Sbjct: 977 SGSSSSYGQHGSGSR-QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYG-PYRSGSGWS 1034
Query: 69 SRFGPYESYDSRSSLGGRDLYRSG-------YGFNEPEQSRFG--GSYGGRFESSYRNSL 119
S GPYES SS G RSG +G + S G GS G+ S ++
Sbjct: 1035 SSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGA 1094
Query: 120 DS----FGGRNQGGSSWEAPYSR----SKLRPGF-MEDRGRENYSSYSSFSSPHMKPAPV 170
S G++ GSS + Y R S PG G SY S + +
Sbjct: 1095 SSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSS 1154
Query: 171 GSRGRGTPAYPESTFGSRNYDAFGGPSTG---RGRGRGHMGDFG 211
G G G S FG ++++ G S+ G G GH +G
Sbjct: 1155 GQHGSGLG--ESSGFG--HHESSSGQSSSYSQHGSGSGHSSGYG 1194
Score = 44.7 bits (104), Expect = 2e-04
Identities = 58/213 (27%), Positives = 75/213 (35%), Gaps = 46/213 (21%)
Query: 20 NGMDRDYGPGSYGGMDRDYGHGSYG-----------GQRSMDSYLNQSYGMDNHSGGGGG 68
+G YG G + GHG +G G+ S + SYG SG G
Sbjct: 1917 SGSSSSYGQHGSGSR-QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYG-SGSGWS 1974
Query: 69 SRFGPYESYDSRSSLGGRDLYRSG-------YGFNEPEQSRFG--GSYGGRFESSYRNSL 119
S GPYES SS G RSG +G + S G GS G+ S ++
Sbjct: 1975 SSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGA 2034
Query: 120 DS----FGGRNQGGSSWEAPYSRSKLRPGFMEDRGRENYSSYSSFSSPHMKPAPVGSRGR 175
S G++ GSS + Y R G G+ GS R
Sbjct: 2035 SSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQR------------------GSGSR 2076
Query: 176 GTPAYPESTFGSRNYDAFG--GPSTGRGRGRGH 206
+P+Y GS + G GP G G GH
Sbjct: 2077 QSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGH 2109
Score = 44.3 bits (103), Expect = 3e-04
Identities = 56/173 (32%), Positives = 68/173 (39%), Gaps = 23/173 (13%)
Query: 40 HGSYGGQRSMDSYLNQSYGMDNHSGGGGGSRFGPYESYDSRSS-LGGRDL---YRSGYGF 95
HGS GQ S S YG SG G S GPYES S SS LG R+ SGYG
Sbjct: 1484 HGSGSGQSSSYS----PYG----SGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYG- 1534
Query: 96 NEPEQSRFGGSYGGRFESSYRNSLDSFGGRNQGGSSWEAPYSRSKLRPGFMEDRGRENYS 155
S ++G +S ++S G + G SS S + G + G
Sbjct: 1535 QHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSS-----SHGQHGSGSSQSSGYGRQG 1589
Query: 156 SYSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRNYDAFG--GPSTGRGRGRGH 206
S S S H GS R +P+Y GS + G G G G GH
Sbjct: 1590 SGSGQSPGH---GQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGH 1639
Score = 43.5 bits (101), Expect = 5e-04
Identities = 55/210 (26%), Positives = 79/210 (37%), Gaps = 34/210 (16%)
Query: 20 NGMDRDYGPGSYGGMDRDYGHGSYGG---------QRSMDSYLNQSYGMDNHSGGGGGSR 70
+G+ YG G + GHG G + S + S+G SG S
Sbjct: 746 SGLSSSYGQHG-SGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHG-SGTSCSSS 803
Query: 71 FGPYESYDSRSSLGGRDLYRSGYGFNEPEQSRFGGSYGGRFESSYR----NSLDSFGGRN 126
G YES ++S G+ SG G+++ GS G F S R + S G++
Sbjct: 804 CGHYESGSGQASGFGQHESGSGQGYSQ------HGSASGHFSSQGRHGSTSGQSSSSGQH 857
Query: 127 QGGSSWEAPYSRSKLRPGFMEDRGRENYSSYSSFSSPHMKPAPVGSRGRG---TPAYPES 183
S + Y + + RGR + S S S H G RG G +P+Y
Sbjct: 858 DSSSGQSSSYGQHESASHHASGRGR--HGSGSGQSPGH------GQRGSGSGQSPSYGRH 909
Query: 184 TFGSRNYDAFG--GPSTGRGRGRGHMGDFG 211
GS + G G +G+ G GH G
Sbjct: 910 GSGSGRSSSSGRHGSGSGQSSGFGHKSSSG 939
Score = 43.1 bits (100), Expect = 7e-04
Identities = 60/226 (26%), Positives = 80/226 (35%), Gaps = 33/226 (14%)
Query: 20 NGMDRDYGPGSYGGMDRD---YGHGSYGGQRSMDSYLNQSYGMDNHSGGGGGSRFGPYES 76
+G + G G G R YG G RS S + SG G S FG +ES
Sbjct: 1120 SGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSS-------GQHGSGLGESSGFGHHES 1172
Query: 77 YDSRSSL----GGRDLYRSGYGFNEPEQSRFGGSYGGRFESSYRNSLDSFGGRNQGGSSW 132
+SS G + SGYG SR G S G S S S G++ GS
Sbjct: 1173 SSGQSSSYSQHGSGSGHSSGYG---QHGSRSGQSSRGERHGSSSGS-SSHYGQHGSGSRQ 1228
Query: 133 EAPYSRSKLRPGFMEDRGR--------ENYSSYSSFSSPHMKPAPVGSRGRGTPAYPEST 184
+ + R G RGR ++ + S S P SR + + +
Sbjct: 1229 SSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHE 1288
Query: 185 FGSRNYDAFGGPSTGRGRGRGH---MGDFGSIHRPGIVVDYQNKST 227
GS + A+ + G G GH G GS D + ST
Sbjct: 1289 SGSGHSSAY----SQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSST 1330
Score = 42.7 bits (99), Expect = 0.001
Identities = 57/231 (24%), Positives = 82/231 (35%), Gaps = 39/231 (16%)
Query: 20 NGMDRDYGPGSYG-GMDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGGG--GSRFGPYES 76
+G R G +G G+ G G + S +Q HS G G GSR G
Sbjct: 1146 SGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSR 1205
Query: 77 YDSRSSLGGRDLY----------RSGYG------FNEPEQSRFG------------GSYG 108
+ S G + SG+G + P + R G GS
Sbjct: 1206 GERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGS 1265
Query: 109 GRFES----SYRNSLDSFGGRNQGGSSWEAPYSRSKLRPGFMEDRGRENYSS--YSSFSS 162
GR S R+ S G+++ GS + YS+ G +G+ +S S+F
Sbjct: 1266 GRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQ 1325
Query: 163 PHMKPAPVGSRG-RGTPAYPESTFGSRNYDAFGGPSTGR-GRGRGHMGDFG 211
S G RG+ + S +G + PS GR G G GH +G
Sbjct: 1326 EGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYG 1376
Score = 42.0 bits (97), Expect = 0.002
Identities = 54/191 (28%), Positives = 67/191 (35%), Gaps = 35/191 (18%)
Query: 29 GSYGGMDRDYG-HGSYGGQRSMD----SYLNQSYGMDNHSGGGGGSRFGPYESYDSRSSL 83
GS G YG HGS G S + S QS G + SG G S + + S S SS
Sbjct: 666 GSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSG 725
Query: 84 GGRDLYRSGYGFNEPEQSRFGG---SYGGRFESSYRNSLDSFGGRNQGGSSWEAPYSRSK 140
+ RSG + G SYG S+++S G QG S +P
Sbjct: 726 YRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSS----GHGRQGSGSGHSP----- 776
Query: 141 LRPGFMEDRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAYPES---TFGSRNYDAFGGPS 197
R + S S SS H G G GT GS FG
Sbjct: 777 ---------SRVRHGSSSGHSSSH------GQHGSGTSCSSSCGHYESGSGQASGFGQHE 821
Query: 198 TGRGRGRGHMG 208
+G G+G G
Sbjct: 822 SGSGQGYSQHG 832
Score = 42.0 bits (97), Expect = 0.002
Identities = 58/193 (30%), Positives = 74/193 (38%), Gaps = 33/193 (17%)
Query: 40 HGSYGGQRSMDSYLNQSYGMDNHSGGGGGSRFGPYESYDSRSSLGGRDLYRSG------- 92
HGS GQ S S YG SG G S GPYES SS G RSG
Sbjct: 2424 HGSGSGQSSSYS----PYG----SGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQ 2475
Query: 93 YGFNEPEQSRFG--GSYGGRFESSYRNSLDS----FGGRNQGGSSWEAPYSR----SKLR 142
+G + S G GS G+ S ++ S G++ GSS + Y R S
Sbjct: 2476 HGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQS 2535
Query: 143 PGF-MEDRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRNYDAFGGPSTG-- 199
PG G SY S + + G G G S FG ++++ G S+
Sbjct: 2536 PGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLG--ESSGFG--HHESSSGQSSSYS 2591
Query: 200 -RGRGRGHMGDFG 211
G G GH +G
Sbjct: 2592 QHGSGSGHSSGYG 2604
Score = 40.8 bits (94), Expect = 0.003
Identities = 60/226 (26%), Positives = 80/226 (35%), Gaps = 33/226 (14%)
Query: 20 NGMDRDYGPGSYGGMDRD---YGHGSYGGQRSMDSYLNQSYGMDNHSGGGGGSRFGPYES 76
+G + G G G R YG G RS S + SG G S FG +ES
Sbjct: 2530 SGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSS-------GQHGSGLGESSGFGHHES 2582
Query: 77 YDSRSSL----GGRDLYRSGYGFNEPEQSRFGGSYGGRFESSYRNSLDSFGGRNQGGSSW 132
+SS G + SGYG SR G S G S S S G++ GS
Sbjct: 2583 SSGQSSSYSQHGSGSGHSSGYG---QHGSRSGQSSRGERHGSSSGS-SSHYGQHGSGSRQ 2638
Query: 133 EAPYSRSKLRPGFMEDRGR--------ENYSSYSSFSSPHMKPAPVGSRGRGTPAYPEST 184
+ + R G RGR ++ + S S P SR + + +
Sbjct: 2639 SSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHE 2698
Query: 185 FGSRNYDAFGGPSTGRGRGRGH---MGDFGSIHRPGIVVDYQNKST 227
GS + A+ + G G GH G GS D + ST
Sbjct: 2699 SGSGHSSAY----SQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSST 2740
Score = 40.4 bits (93), Expect = 0.005
Identities = 52/175 (29%), Positives = 66/175 (37%), Gaps = 27/175 (15%)
Query: 39 GHGSYGGQRSMDSYLNQSYGMDNHSGGGGGSRFGPYESYDSRSSLGGRDLYRSGYGFNEP 98
GH S GQ S + S G SG G S FG +ES +SS G + SG G +
Sbjct: 317 GHSSSHGQHGSGSSYSYSRG-HYESGSGQTSGFGQHESGSGQSS--GYSKHGSGSGHSSS 373
Query: 99 EQSRFGGSYGGRFESSYRNSLDSFGGRNQGGSSWEAPYSRSKLRPGFMEDRGRENYSSYS 158
+ GS G+ SS Q GSS S + GR +SS S
Sbjct: 374 QGQH--GSTSGQASSS-----------GQHGSSSRQSSSYGQHESASRHSSGRGQHSSGS 420
Query: 159 SFSSPHMKPAPVGSRGRGTPAYPESTFGSRNYDAFGGPSTGRG--RGRGHMGDFG 211
S H G RG G+ P S ++ FG S+ G G+ FG
Sbjct: 421 GQSPGH------GQRGSGSGQSPSS---GQHGTGFGRSSSSGPYVSGSGYSSGFG 466
Score = 40.4 bits (93), Expect = 0.005
Identities = 61/210 (29%), Positives = 84/210 (40%), Gaps = 22/210 (10%)
Query: 9 HSACRNTYQGFNGMDRDYGP-GSYGGMDRDYG-HGS-YGGQRSMDSYLNQSYGMDNHSGG 65
HS+ R + +G +G GS G G HG+ +G S Y+ SG
Sbjct: 409 HSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYV---------SGS 459
Query: 66 GGGSRFGPYESYDSRSSLGGRDLYRSGYGFNE---PEQSRFGGSYGGRFESSYRNSLDSF 122
G S FG +ES SS G + SG G + SR G S G + S S S+
Sbjct: 460 GYSSGFGHHESSSEHSS--GYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSY 517
Query: 123 GGRNQGGSSWEAPYSRSKLRPGFMEDRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAYPE 182
G++ GS +SR G R + S S SS + P GS GR + P
Sbjct: 518 -GQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSY-GPHGYGS-GRSSSRGPY 574
Query: 183 STFGSRNYDAFGGPSTGRGRGRGHMGDFGS 212
+ GS + G + G+ G+ G GS
Sbjct: 575 ES-GSGHSSGLGHQESRSGQSSGY-GQHGS 602
Score = 40.4 bits (93), Expect = 0.005
Identities = 51/199 (25%), Positives = 67/199 (33%), Gaps = 10/199 (5%)
Query: 18 GFNGMDRDYGPGSYGGMDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGGGGSRFGPYESY 77
G G + P S G GH S GQ S + S G S G S FG +ES
Sbjct: 1233 GRQGSGSGHSP-SRGRHGSGLGHSSSHGQHGSGSGRSSSRG-PYESRSGHSSVFGQHESG 1290
Query: 78 DSRSSLGGRDLYRSGYGFNEPEQSRFGGSYGGRFESSYRNSLDSFGGRNQGGSSWEAPYS 137
SS + SG+ ++ + G + S G GSS + Y
Sbjct: 1291 SGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYG 1350
Query: 138 RSKLRPGFMEDRGRE-----NYSSYSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRNYDA 192
R G RGR + SSY S + G G G+ S FG +
Sbjct: 1351 RHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSG--QSSGFGHHESSS 1408
Query: 193 F-GGPSTGRGRGRGHMGDF 210
+ T G G GH +
Sbjct: 1409 WQSSGCTQHGSGSGHSSSY 1427
Score = 40.0 bits (92), Expect = 0.006
Identities = 56/196 (28%), Positives = 78/196 (39%), Gaps = 24/196 (12%)
Query: 30 SYGGMDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGGGGSRFGPYESYDSRSSLGGRDLY 89
SYG + H S G+ S + +G SG G +G + S RSS GR
Sbjct: 866 SYGQHESASHHASGRGRHGSGSGQSPGHGQRG-SGSGQSPSYGRHGSGSGRSSSSGRHGS 924
Query: 90 RSGYGFNEPEQSRFGGSYGGRFE---SSYRNSLDSFGGRN-------QGGSSWEAPYSRS 139
SG +S G S G S + +S + G R+ Q GSS + S
Sbjct: 925 GSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYG 984
Query: 140 KLRPGFMEDRGRENYSSYSSFSSPHMKPAPVGSRGR-GTPAYPESTFGSRNYDAFGGPST 198
+ G + G + S S S P+P SRGR G+ + S++G Y + G S+
Sbjct: 985 QHGSGSRQSLGHGQHGSGSGQS-----PSP--SRGRHGSGSGQSSSYGP--YRSGSGWSS 1035
Query: 199 GRG---RGRGHMGDFG 211
RG G GH G
Sbjct: 1036 SRGPYESGSGHSSGLG 1051
Score = 40.0 bits (92), Expect = 0.006
Identities = 50/199 (25%), Positives = 69/199 (34%), Gaps = 10/199 (5%)
Query: 18 GFNGMDRDYGPGSYGGMDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGGGGSRFGPYESY 77
G G + P S G GH S GQ S + S G S G S FG +ES
Sbjct: 2173 GRQGSGSGHSP-SRGRHGSGSGHSSSHGQHGSGSGRSSSRG-PYESRSGHSSVFGQHESG 2230
Query: 78 DSRSSLGGRDLYRSGYGFNEPEQSRFGGSYGGRFESSYRNSLDSFGGRNQGGSSWEAPYS 137
SS + SG+ ++ + G + S G++ GSS + Y
Sbjct: 2231 SGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYG 2290
Query: 138 RSKLRPGFMEDRGRE-----NYSSYSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRNYDA 192
+ G RGR + SSY S + G G G+ S FG +
Sbjct: 2291 QQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSG--QSSGFGHHESSS 2348
Query: 193 FGGPS-TGRGRGRGHMGDF 210
+ T G G GH +
Sbjct: 2349 WQSSGYTQHGSGSGHSSSY 2367
Score = 39.7 bits (91), Expect = 0.008
Identities = 45/178 (25%), Positives = 63/178 (35%), Gaps = 9/178 (5%)
Query: 39 GHGSYGGQRSMDSYLNQSYGMDNHSGGGGGSRFGPYESYDSRSSLGGRDLYRSGYGFNEP 98
GH S GQ S + S G S G S FG +ES SS + SG+ ++
Sbjct: 1723 GHSSSHGQHGSGSGRSSSRG-PYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQG 1781
Query: 99 EQSRFGGSYGGRFESSYRNSLDSFGGRNQGGSSWEAPYSRSKLRPGFMEDRGRE-----N 153
+ G + S G++ GSS + Y + G RGR +
Sbjct: 1782 QHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGH 1841
Query: 154 YSSYSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRNYDAFGGPS-TGRGRGRGHMGDF 210
SSY S + G G G+ S FG ++ T G G GH +
Sbjct: 1842 SSSYGQHGSGSGWSSSSGRHGSGSG--QSSGFGHHESSSWQSSGYTQHGSGSGHSSSY 1897
Score = 39.7 bits (91), Expect = 0.008
Identities = 46/199 (23%), Positives = 63/199 (31%), Gaps = 6/199 (3%)
Query: 20 NGMDRDYGPGSYG-GMDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGGG--GSRFGPYES 76
+G R G +G G+ G G + S +Q HS G G GSR G
Sbjct: 2556 SGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSR 2615
Query: 77 YDSRSSLGGRDLYRSGYGFNEPEQSRFGGSYGGRFESSYRNSLDSFGGRNQGGSSWEAPY 136
+ S G + +G + S G G +S R S G + +
Sbjct: 2616 GERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGS 2675
Query: 137 SRSKLRPGFMEDRGRENYSSYSSFSSPHMKPAPVGSRGRG---TPAYPESTFGSRNYDAF 193
RS R + G + S H G G + ST G +
Sbjct: 2676 GRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQ 2735
Query: 194 GGPSTGRGRGRGHMGDFGS 212
G STG+ GH G S
Sbjct: 2736 EGSSTGQSSSYGHRGSGSS 2754
Score = 38.9 bits (89), Expect = 0.013
Identities = 47/181 (25%), Positives = 61/181 (33%), Gaps = 24/181 (13%)
Query: 29 GSYGGMDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGGGGSRFGPYESYDSRSSLGGRDL 88
GS G +GH S GQ S G H G G S SY+ S G+
Sbjct: 923 GSGSGQSSGFGHKSSSGQSS---------GYTQHGSGSGHS-----SSYEQHGSRSGQSS 968
Query: 89 YRSGYGFNEPEQSRFGGSYGGRFESSYRNSLDSFGGRNQGGSSWEAPY-SRSKLRPGFME 147
+G + S +G G S S G G S ++P SR + G +
Sbjct: 969 RSEQHGSSSGSSSSYGQHGSG--------SRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQ 1020
Query: 148 DRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRNYDAFGGPSTGRGRGRGHM 207
Y S S +SS P GS + ES G + G S+G G
Sbjct: 1021 SSSYGPYRSGSGWSSSR-GPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQH 1079
Query: 208 G 208
G
Sbjct: 1080 G 1080
Score = 37.7 bits (86), Expect = 0.029
Identities = 49/202 (24%), Positives = 71/202 (35%), Gaps = 27/202 (13%)
Query: 39 GHGSYGGQRSMDSYLNQSYGMDN--------HSGGGGGSRFGPYESYDSRSSLGGRDL-- 88
G S G Q S + SYG H G GS P S S G+
Sbjct: 1905 GQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSY 1964
Query: 89 --YRSGYGFNE---PEQSRFGGSYGGRFESSYRNSLDSFG--GRNQGGSSWEAPYSRSKL 141
Y SG G++ P +S G S G S +G G + G SS + +
Sbjct: 1965 GPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASG 2024
Query: 142 RPGFMEDRGREN--YSSYSSFSSPHMKPAPVGSRGRG---TPAYPESTFGSRNYDAFGGP 196
+ G + SS+ S + + G +G G +P + + GSR ++G
Sbjct: 2025 QSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 2084
Query: 197 STGRGRGRGHMGDFGSIHRPGI 218
+G GR H PG+
Sbjct: 2085 GSGSGRSSS-----SGQHGPGL 2101
Score = 37.7 bits (86), Expect = 0.029
Identities = 48/198 (24%), Positives = 71/198 (35%), Gaps = 26/198 (13%)
Query: 29 GSYGGMDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGGGGSRFGPYESYDSRSSLGGRDL 88
GS G YG G ++S+ H G GS P S S G+
Sbjct: 2384 GSSSGSSSSYGQHGSGSRQSL-----------GHGQHGSGSGQSPSPSRGRHGSGSGQSS 2432
Query: 89 ----YRSGYGFNE---PEQSRFGGSYGGRFESSYRNSLDSFG--GRNQGGSSWEAPYSRS 139
Y SG G++ P +S G S G S +G G + G SS + +
Sbjct: 2433 SYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGST 2492
Query: 140 KLRPGFMEDRGREN--YSSYSSFSSPHMKPAPVGSRGRG---TPAYPESTFGSRNYDAFG 194
+ G + SS+ S + + G +G G +P + + GSR ++G
Sbjct: 2493 SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYG 2552
Query: 195 GPSTGRGRGRGHMGDFGS 212
+G GR G GS
Sbjct: 2553 RHGSGSGRS-SSSGQHGS 2569
Score = 37.0 bits (84), Expect = 0.050
Identities = 44/193 (22%), Positives = 64/193 (33%), Gaps = 11/193 (5%)
Query: 29 GSYGGMDRDYGHGSY-GGQRSMDSYLNQSYGMDN-------HSGGGGGSRFGPYESYDSR 80
GS G G + G R SY YG SG G S G ES +
Sbjct: 534 GSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQ 593
Query: 81 SSLGGRDLYRSGYGFNEPEQSRFGGSYGGRFESSYRNSLDSFGGRNQGGSSWEAPYSRSK 140
SS G+ SG+ + G + + S G++ GSS + Y +
Sbjct: 594 SSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQG 653
Query: 141 LRPGFMEDRGR--ENYSSYSSFSSPHMKPAPVGSRG-RGTPAYPESTFGSRNYDAFGGPS 197
G RGR ++ SS+ S G G+ + S FG ++
Sbjct: 654 SGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGY 713
Query: 198 TGRGRGRGHMGDF 210
+ G G H +
Sbjct: 714 SQHGSGSSHSSGY 726
Score = 36.6 bits (83), Expect = 0.065
Identities = 48/198 (24%), Positives = 68/198 (34%), Gaps = 26/198 (13%)
Query: 29 GSYGGMDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGGGGSRFGPYESYDSRSSLGGRDL 88
GS G YG G ++S+ H G GS P S S G+
Sbjct: 1444 GSSSGSSSSYGQHGSGSRQSL-----------GHGQHGSGSGQSPSPSRGRHGSGSGQSS 1492
Query: 89 YRSGYGFNEPEQSRFGGSYGGRFESSYRNSLDSFGGRNQG------GSSWEAPYSRSKLR 142
S YG S G G SS +S G++ G S + + +
Sbjct: 1493 SYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGST 1552
Query: 143 PGFMEDRGRENYSSYSSFS-----SPHMKPAPVGSRGRG---TPAYPESTFGSRNYDAFG 194
G G+ SS S S S + + G +G G +P + + GSR ++G
Sbjct: 1553 SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYG 1612
Query: 195 GPSTGRGRGRGHMGDFGS 212
+G GR G GS
Sbjct: 1613 RHGSGSGRS-SSSGQHGS 1629
Score = 34.7 bits (78), Expect = 0.25
Identities = 46/190 (24%), Positives = 66/190 (34%), Gaps = 28/190 (14%)
Query: 29 GSYGGMDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGGGGSRFGP------YESYDSRSS 82
GS G YG G ++S+ HS G GS P +ES +SS
Sbjct: 508 GSSAGSSSSYGQHGSGSRQSL-----------GHSRHGSGSGQSPSPSRGRHESGSRQSS 556
Query: 83 LGGRDLYRSGYGFNEPEQSRFGGSYGGRFESSYRNSLDSFGGRNQGGSSWEAPYSRSKLR 142
G Y SG + G G R+ S G++ S + + +
Sbjct: 557 SYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGST 616
Query: 143 PGFMEDRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRNYDAFGGPSTGR-G 201
G G+ + + S SS H G G G+ S +G + + PS GR G
Sbjct: 617 SGQSSSCGQ--HGATSGQSSSH------GQHGSGSS--QSSRYGQQGSGSGQSPSRGRHG 666
Query: 202 RGRGHMGDFG 211
GH +G
Sbjct: 667 SDFGHSSSYG 676
Score = 34.3 bits (77), Expect = 0.32
Identities = 48/198 (24%), Positives = 69/198 (34%), Gaps = 14/198 (7%)
Query: 29 GSYG-GMDRDYGHGSYGGQRSMD-------SYLNQSYGMDNH-SGGGGGSRFGPYESYDS 79
G +G G + GHG G S L S H SG G S GPYES
Sbjct: 2630 GQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRLG 2689
Query: 80 RSSLGGRDLYRSGYGFNEPEQSRFGGSYGGRFESSYRNSLDSFGGRNQGGSSWEAPYSRS 139
SS+ G+ + SG G + GS + + ++ +Q GSS S
Sbjct: 2690 HSSVFGQ--HESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYG 2747
Query: 140 KLRPGFMEDRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRNYDAFGGPSTG 199
G + G Y + + S + GS + +Y + GS + +G
Sbjct: 2748 HRGSGSSQSSG---YGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSG 2804
Query: 200 RGRGRGHMGDFGSIHRPG 217
G+ GS H G
Sbjct: 2805 SGQDGYSYCKGGSNHDGG 2822
Score = 30.8 bits (68), Expect = 3.6
Identities = 23/61 (37%), Positives = 24/61 (39%), Gaps = 10/61 (16%)
Query: 29 GSYGGMDRDYG-HGSYGGQRSMDSYLNQSYGMD---------NHSGGGGGSRFGPYESYD 78
GS G YG HGS GQ S S G D NH GG GS F + S
Sbjct: 2776 GSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSNHDGGSSGSYFLSFPSST 2835
Query: 79 S 79
S
Sbjct: 2836 S 2836
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 53.5 bits (127), Expect = 5e-07
Identities = 51/166 (30%), Positives = 75/166 (45%), Gaps = 9/166 (5%)
Query: 423 QHLKSPDHIKGKQAYKEQIKRESVLTATSILNNPIVKARYERFVKGENPFEIQDHSQDQQ 482
QH + I+ + E+ + E LTA I V + E+ E E + +++
Sbjct: 449 QHKFVEEIIEETKVEDEKSEMEEALTA--ITEELAVSMKEEKKEAAEEKEEEPEAEEEEV 506
Query: 483 IEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGGIEGEGNI---QGVG 539
+ E EEE +++EEE EE E +E + ++ EGG E EG+ +G
Sbjct: 507 AAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQ 566
Query: 540 EGGEVGVVGEVEGVGEVEE--VEELEEETAKEEP--ADFPVEQPEE 581
E GE E E EE VEE EE A +E AD VE+PE+
Sbjct: 567 EEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEK 612
Score = 48.5 bits (114), Expect = 2e-05
Identities = 77/344 (22%), Positives = 142/344 (41%), Gaps = 58/344 (16%)
Query: 263 EKISLSKSPTKT---DPKNEEEEKRRIEARREKQRRRREKNSEKYGDGYRMAFTCSFCKF 319
E+++ KSP K + K EE EK E + E++ S++ +G S +
Sbjct: 504 EEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEE 563
Query: 320 RTFEEKDIELHLESSSHQETLDHIQKQTKFDKVVM--EFLHECMVNKFKKTSIRKQQTNN 377
EE + E E E + + + K ++V E + + V K +K ++
Sbjct: 564 GEQEEGETEAEAEGEE-AEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPV 622
Query: 378 QTEVVKIIEKDVMEGVTVDDHMMKVETVHCSACSVYIPALHSSVQQH-----LKSPDHIK 432
+ + + K +E P S V++ KSP K
Sbjct: 623 EEKGKSPVPKSPVEEKGKS------------------PVPKSPVEEKGKSPVPKSPVEEK 664
Query: 433 GKQAYKEQIKRESVLTATSILNNPIVKARYERFV-----KGENPFEIQDHSQDQQIEGDE 487
GK + E + + +P+ +A+ + V K E E+++ +++++E E
Sbjct: 665 GKSPVSKSPVEEKA--KSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKE 722
Query: 488 E------DEEKIDEPIEEEEDED------------EEEEAEEVGEVEEVEEVEEVR-EGG 528
E +++K + P++EE + E+E EE +++ +E E+ EGG
Sbjct: 723 EKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGG 782
Query: 529 IEGEGNIQGV--GEGGEVGVVGEVEGVGEVEEVEELEEETAKEE 570
E EG+ +G ++ V GEVEG EVE+ E E+ + +EE
Sbjct: 783 SEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQ-ETKEKGSGREE 825
Score = 35.4 bits (80), Expect = 0.15
Identities = 36/139 (25%), Positives = 61/139 (43%), Gaps = 7/139 (5%)
Query: 421 VQQHLKSPDHIKGKQAYKEQIKRESVLTATSILNNPIVKARYERFVKGENPFEIQDHSQD 480
V++ + P + K+ + +K E+V +I + VK E+ K E +Q +
Sbjct: 718 VEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKS--VKVHLEKETKEEGK-PLQQEKEK 774
Query: 481 QQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVE-EVREGGIEGEGNIQGVG 539
++ G+ EE E ++ +E+ GEVE EEVE E +E G E V
Sbjct: 775 EKAGGEGGSEE---EGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVT 831
Query: 540 EGGEVGVVGEVEGVGEVEE 558
G ++ E +G + EE
Sbjct: 832 NGLDLSPADEKKGGDKSEE 850
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 53.5 bits (127), Expect = 5e-07
Identities = 51/166 (30%), Positives = 75/166 (45%), Gaps = 9/166 (5%)
Query: 423 QHLKSPDHIKGKQAYKEQIKRESVLTATSILNNPIVKARYERFVKGENPFEIQDHSQDQQ 482
QH + I+ + E+ + E LTA I V + E+ E E + +++
Sbjct: 73 QHKFVEEIIEETKVEDEKSEMEEALTA--ITEELAVSMKEEKKEAAEEKEEEPEAEEEEV 130
Query: 483 IEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGGIEGEGNI---QGVG 539
+ E EEE +++EEE EE E +E + ++ EGG E EG+ +G
Sbjct: 131 AAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQ 190
Query: 540 EGGEVGVVGEVEGVGEVEE--VEELEEETAKEEP--ADFPVEQPEE 581
E GE E E EE VEE EE A +E AD VE+PE+
Sbjct: 191 EEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEK 236
Score = 48.5 bits (114), Expect = 2e-05
Identities = 77/344 (22%), Positives = 142/344 (41%), Gaps = 58/344 (16%)
Query: 263 EKISLSKSPTKT---DPKNEEEEKRRIEARREKQRRRREKNSEKYGDGYRMAFTCSFCKF 319
E+++ KSP K + K EE EK E + E++ S++ +G S +
Sbjct: 128 EEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEE 187
Query: 320 RTFEEKDIELHLESSSHQETLDHIQKQTKFDKVVM--EFLHECMVNKFKKTSIRKQQTNN 377
EE + E E E + + + K ++V E + + V K +K ++
Sbjct: 188 GEQEEGETEAEAEGEE-AEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPV 246
Query: 378 QTEVVKIIEKDVMEGVTVDDHMMKVETVHCSACSVYIPALHSSVQQH-----LKSPDHIK 432
+ + + K +E P S V++ KSP K
Sbjct: 247 EEKGKSPVPKSPVEEKGKS------------------PVPKSPVEEKGKSPVPKSPVEEK 288
Query: 433 GKQAYKEQIKRESVLTATSILNNPIVKARYERFV-----KGENPFEIQDHSQDQQIEGDE 487
GK + E + + +P+ +A+ + V K E E+++ +++++E E
Sbjct: 289 GKSPVSKSPVEEKA--KSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKE 346
Query: 488 E------DEEKIDEPIEEEEDED------------EEEEAEEVGEVEEVEEVEEVR-EGG 528
E +++K + P++EE + E+E EE +++ +E E+ EGG
Sbjct: 347 EKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGG 406
Query: 529 IEGEGNIQGV--GEGGEVGVVGEVEGVGEVEEVEELEEETAKEE 570
E EG+ +G ++ V GEVEG EVE+ E E+ + +EE
Sbjct: 407 SEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQ-ETKEKGSGREE 449
Score = 35.4 bits (80), Expect = 0.15
Identities = 36/139 (25%), Positives = 61/139 (43%), Gaps = 7/139 (5%)
Query: 421 VQQHLKSPDHIKGKQAYKEQIKRESVLTATSILNNPIVKARYERFVKGENPFEIQDHSQD 480
V++ + P + K+ + +K E+V +I + VK E+ K E +Q +
Sbjct: 342 VEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKS--VKVHLEKETKEEGK-PLQQEKEK 398
Query: 481 QQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVE-EVREGGIEGEGNIQGVG 539
++ G+ EE E ++ +E+ GEVE EEVE E +E G E V
Sbjct: 399 EKAGGEGGSEE---EGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVT 455
Query: 540 EGGEVGVVGEVEGVGEVEE 558
G ++ E +G + EE
Sbjct: 456 NGLDLSPADEKKGGDKSEE 474
>gi|33946282 hypothetical protein LOC25962 isoform 1 [Homo sapiens]
Length = 1812
Score = 53.5 bits (127), Expect = 5e-07
Identities = 33/118 (27%), Positives = 57/118 (48%), Gaps = 16/118 (13%)
Query: 466 VKGENPFEIQDHSQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVR 525
V E + + +++Q E EEDE+ +D EE+EDED+ + + E EE +E E
Sbjct: 228 VPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEE--- 284
Query: 526 EGGIEGEGNIQGVGEGGEVGVVGEVEGVGEVE---------EVEELEEETAKEEPADF 574
EGE + +G G+ G + + +G+ ++E +VE E+ A P +
Sbjct: 285 ----EGEEDEEGEGDDGYEQISSDEDGIADLERETFKYPNFDVEYTAEDLASVPPMTY 338
>gi|33946280 hypothetical protein LOC25962 isoform 2 [Homo sapiens]
Length = 1147
Score = 53.5 bits (127), Expect = 5e-07
Identities = 33/118 (27%), Positives = 57/118 (48%), Gaps = 16/118 (13%)
Query: 466 VKGENPFEIQDHSQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVR 525
V E + + +++Q E EEDE+ +D EE+EDED+ + + E EE +E E
Sbjct: 228 VPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEE--- 284
Query: 526 EGGIEGEGNIQGVGEGGEVGVVGEVEGVGEVE---------EVEELEEETAKEEPADF 574
EGE + +G G+ G + + +G+ ++E +VE E+ A P +
Sbjct: 285 ----EGEEDEEGEGDDGYEQISSDEDGIADLERETFKYPNFDVEYTAEDLASVPPMTY 338
>gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b
[Homo sapiens]
Length = 372
Score = 52.8 bits (125), Expect = 9e-07
Identities = 49/154 (31%), Positives = 59/154 (38%), Gaps = 17/154 (11%)
Query: 16 YQGFNGMDRDYGPGSYGGMDRDYG----HGSYGGQRSMDSYLNQSYGMDNHSGGGGGSRF 71
+ G G G G YGG Y G YGG S ++ YG G GS +
Sbjct: 222 FSGRGGFGGSRGGGGYGGSGDGYNGFGNDGGYGGGGPGYSGGSRGYGSGGQGYGNQGSGY 281
Query: 72 GPYESYDSRSSLGGRDLYRSGYGFNEPEQSRFGGSYGGRFESSYRNSLDSFG---GRNQG 128
G SYDS ++ GG GF S FGG +Y N +FG G N G
Sbjct: 282 GGSGSYDSYNNGGGG-------GFGGGSGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFG 334
Query: 129 GSSWEAPYSRSKLRPGFMEDRGRENYSSYSSFSS 162
G S PY F + R + Y SS SS
Sbjct: 335 GRS-SGPYGGG--GQYFAKPRNQGGYGGSSSSSS 365
Score = 37.4 bits (85), Expect = 0.038
Identities = 50/190 (26%), Positives = 66/190 (34%), Gaps = 43/190 (22%)
Query: 33 GMDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGGGGSRFGPYESYDSRSSLGGRDLYRSG 92
G R + ++ S+D + Q Y H+ G S +S RSG
Sbjct: 143 GKKRGFAFVTFDDHDSVDKIVIQKY----HTVNGHNCEVRKALSKQEMASASSSQRGRSG 198
Query: 93 YGFNEPEQSRFGGSYGGRFESSYRNSLDSFG-GRNQGGSSWEAPYSRSKLRPGFMEDRGR 151
G FGG GG F + D+FG G N G R GF RG
Sbjct: 199 SG-------NFGGGRGGGFGGN-----DNFGRGGNFSG------------RGGFGGSRGG 234
Query: 152 ENYSS----YSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRNYDAFGGPSTGRGRGRGHM 207
Y Y+ F + G G G P Y + GSR Y + G +G G G
Sbjct: 235 GGYGGSGDGYNGFGND-------GGYGGGGPGY---SGGSRGYGSGGQGYGNQGSGYGGS 284
Query: 208 GDFGSIHRPG 217
G + S + G
Sbjct: 285 GSYDSYNNGG 294
>gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isoform
B1 [Homo sapiens]
Length = 353
Score = 52.4 bits (124), Expect = 1e-06
Identities = 50/160 (31%), Positives = 65/160 (40%), Gaps = 24/160 (15%)
Query: 56 SYGMDNHSGGGGGSRFGPYESYDSRSSLGGRDLYRSGYGFNEPEQSRFGGSYGGRFESS- 114
++G + GGGG FGP + R GG D Y SG GF + GG GG F S
Sbjct: 206 NFGFGDSRGGGGN--FGPGPGSNFR---GGSDGYGSGRGFGDGYNGYGGGPGGGNFGGSP 260
Query: 115 -YRNSLDSFGGRNQGGSSWEAPYSRSKLRPGFMEDRGRENYSS--YSSFSSPHMKPAPVG 171
Y +GG G + Y G ++ G NY S Y+ F + + +P+ G
Sbjct: 261 GYGGGRGGYGGGGPGYGNQGGGYG------GGYDNYGGGNYGSGNYNDFGNYNQQPSNYG 314
Query: 172 SRGRGTPAYPESTFGSRNYDAFGGPSTGRGRGRGHMGDFG 211
P + GSRN GGP G G G G G
Sbjct: 315 ------PMKSGNFGGSRN---MGGPYGGGNYGPGGSGGSG 345
Score = 48.1 bits (113), Expect = 2e-05
Identities = 51/180 (28%), Positives = 64/180 (35%), Gaps = 47/180 (26%)
Query: 25 DYGPGSYGGMDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGGGGSRFGPYESYDSRSSLG 84
++GPG G + G YG R G + + GG GG FG Y G
Sbjct: 218 NFGPGP--GSNFRGGSDGYGSGRGFGD------GYNGYGGGPGGGNFGGSPGYG-----G 264
Query: 85 GRDLYRSGYGFNEPEQSRFGGSYGGRFESSYRNSLDSFGGRNQGGSSWEAPYSRSKLRPG 144
G R GYG P GG YGG + D++GG N G ++
Sbjct: 265 G----RGGYGGGGPGYGNQGGGYGGGY--------DNYGGGNYGSGNY------------ 300
Query: 145 FMEDRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRNYDAFGGPSTGRGRGR 204
D G NY+ S P GSR G P +G NY G +G GR
Sbjct: 301 --NDFG--NYNQQPSNYGPMKSGNFGGSRNMGGP------YGGGNYGPGGSGGSGGYGGR 350
>gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform A2
[Homo sapiens]
Length = 341
Score = 52.4 bits (124), Expect = 1e-06
Identities = 50/160 (31%), Positives = 65/160 (40%), Gaps = 24/160 (15%)
Query: 56 SYGMDNHSGGGGGSRFGPYESYDSRSSLGGRDLYRSGYGFNEPEQSRFGGSYGGRFESS- 114
++G + GGGG FGP + R GG D Y SG GF + GG GG F S
Sbjct: 194 NFGFGDSRGGGGN--FGPGPGSNFR---GGSDGYGSGRGFGDGYNGYGGGPGGGNFGGSP 248
Query: 115 -YRNSLDSFGGRNQGGSSWEAPYSRSKLRPGFMEDRGRENYSS--YSSFSSPHMKPAPVG 171
Y +GG G + Y G ++ G NY S Y+ F + + +P+ G
Sbjct: 249 GYGGGRGGYGGGGPGYGNQGGGYG------GGYDNYGGGNYGSGNYNDFGNYNQQPSNYG 302
Query: 172 SRGRGTPAYPESTFGSRNYDAFGGPSTGRGRGRGHMGDFG 211
P + GSRN GGP G G G G G
Sbjct: 303 ------PMKSGNFGGSRN---MGGPYGGGNYGPGGSGGSG 333
Score = 48.1 bits (113), Expect = 2e-05
Identities = 51/180 (28%), Positives = 64/180 (35%), Gaps = 47/180 (26%)
Query: 25 DYGPGSYGGMDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGGGGSRFGPYESYDSRSSLG 84
++GPG G + G YG R G + + GG GG FG Y G
Sbjct: 206 NFGPGP--GSNFRGGSDGYGSGRGFGD------GYNGYGGGPGGGNFGGSPGYG-----G 252
Query: 85 GRDLYRSGYGFNEPEQSRFGGSYGGRFESSYRNSLDSFGGRNQGGSSWEAPYSRSKLRPG 144
G R GYG P GG YGG + D++GG N G ++
Sbjct: 253 G----RGGYGGGGPGYGNQGGGYGGGY--------DNYGGGNYGSGNY------------ 288
Query: 145 FMEDRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRNYDAFGGPSTGRGRGR 204
D G NY+ S P GSR G P +G NY G +G GR
Sbjct: 289 --NDFG--NYNQQPSNYGPMKSGNFGGSRNMGGP------YGGGNYGPGGSGGSGGYGGR 338
>gi|153252068 testes-specific heterogenous nuclear ribonucleoprotein
G-T [Homo sapiens]
Length = 392
Score = 52.4 bits (124), Expect = 1e-06
Identities = 37/94 (39%), Positives = 43/94 (45%), Gaps = 9/94 (9%)
Query: 6 DYTHSACRNTYQGFNGMDRDYGPGSYGGMDRDYG-HGSYGGQRS-MDSY---LNQSYGMD 60
DY HS+ R+ DRD YGG DRDYG H S G R +SY + G
Sbjct: 242 DYGHSSVRDDCPLRGYSDRD----GYGGRDRDYGDHLSRGSHREPFESYGELRGAAPGRG 297
Query: 61 NHSGGGGGSRFGPYESYDSRSSLGGRDLYRSGYG 94
GGG R+ Y Y + GGRD Y S YG
Sbjct: 298 TPPSYGGGGRYEEYRGYSPDAYSGGRDSYSSSYG 331
>gi|223890219 RNA binding motif protein, X-linked-like 3 [Homo
sapiens]
Length = 1067
Score = 52.0 bits (123), Expect = 2e-06
Identities = 49/152 (32%), Positives = 70/152 (46%), Gaps = 17/152 (11%)
Query: 5 DDYT--HSACRNTYQGFNGMDRDYGPGSYGGMDRDYGHGSYGGQRSMDSYLNQSYGMDNH 62
D YT +S R+++ G YG G + +YGG R ++S N S+G +
Sbjct: 884 DHYTEAYSRGRDSFSNSYGRSDHYGRGGCYEEYQGRSPNAYGGGRGLNSS-NNSHGRSHR 942
Query: 63 SGGGGGSRFGPYESYDSRSSLGGRDLYRSGYGFNEPEQSRFGGSYGGRFESSYRNSL-DS 121
GGGG R+ Y + GGRD YG ++ R+GG GG +E Y+ SL D+
Sbjct: 943 YGGGG--RYEEYRGPSPDAHSGGRDSSIKSYGLSD----RYGG--GGHYE-EYQGSLPDA 993
Query: 122 FGG---RNQGGSSWEAPYSRSKLRPGFMEDRG 150
+ G R+ YSR + R G DRG
Sbjct: 994 YSGDHDRSSNSYGRSDRYSRGRDRVG-RPDRG 1024
Score = 44.7 bits (104), Expect = 2e-04
Identities = 60/209 (28%), Positives = 82/209 (39%), Gaps = 27/209 (12%)
Query: 9 HSACRNTYQGFNGMDRDYG-PGSYGGMDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGGG 67
HS+ N+Y G YG G Y R H ++ G S D+Y + GG
Sbjct: 534 HSSSSNSY----GQSHRYGGEGRYEYRGRS--HDAHSGGCSADAYSGGHDSSSQSNRYGG 587
Query: 68 GSRFGPYESYDSRSSLGGR--DLYRSGYGFNEPEQSRFGGSYGGRFESSYRNSLDSFGGR 125
G + Y ++ GGR + Y G+ + R+GG GGR+E SLD+
Sbjct: 588 GGCYEEYRGRSLDANSGGRSPNAYSGGHD-SSSWSHRYGG--GGRYEEYRGRSLDA---- 640
Query: 126 NQGGSSWEAPYSRSKLRPGFMEDRGREN-YSSYSSFSSPHMKPAPVGSRGRGTPAYPEST 184
N GG S +A YS G + G+ N Y + + S GR AY
Sbjct: 641 NSGGRSPDA-YS------GGHDSSGQSNCYGGGGRYEEYRGRLLDANSGGRSPDAYSGGH 693
Query: 185 FGSRNYDAFGGPSTGR-GRGRGHMGDFGS 212
S + +GG GR RGH D S
Sbjct: 694 DSSSQSNRYGG--GGRYEEYRGHSLDANS 720
Score = 38.5 bits (88), Expect = 0.017
Identities = 59/223 (26%), Positives = 79/223 (35%), Gaps = 38/223 (17%)
Query: 5 DDYTHSACRNTYQG-----FNGMDRDYGPGSYGGMDRDYGHG--SYGGQRSMDSYLNQSY 57
D Y+ Y G NG R G G + G ++ G R+ S SY
Sbjct: 355 DAYSRDHSPKAYSGGRSSSSNGYSRSDRYGEEGCYEEYRGRSPDAHSGGRNSSS---NSY 411
Query: 58 GMDNHSGGGGGSRFGPYESYDSRSSLGGR-----------DLYRSGYGFNEPEQSRFGGS 106
G +H GG G R+ Y + GGR D Y G+ + G
Sbjct: 412 GQSHHYGGEG--RYEEYRGRSHEARSGGRSTDAHSRGRSDDAYSGGHDSSSWSDCCGG-- 467
Query: 107 YGGRFESSYRNSLDSFGGRNQGGSSWEAPYSRSKLRPGFMEDRGRENYSSYSSFSSPHMK 166
GGR+E SLD+ N GG S EA YS + + R + + H
Sbjct: 468 -GGRYEEYQGRSLDA----NSGGCSPEA-YSGGHDNSSWSD---RYGVGGHYEENRGHSL 518
Query: 167 PAPVGSRGRGTPAYPESTFGSRNY---DAFGGPSTGRGRGRGH 206
A G R T + S+ S +Y +GG RGR H
Sbjct: 519 DANSGGRSPDTHSGGHSS-SSNSYGQSHRYGGEGRYEYRGRSH 560
Score = 38.5 bits (88), Expect = 0.017
Identities = 55/215 (25%), Positives = 71/215 (33%), Gaps = 30/215 (13%)
Query: 20 NGMDRDYGPGSYGGMDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGGGGSRFGPYESYDS 79
+G YG G R + G RS D+Y + GGG R+ Y +
Sbjct: 657 SGQSNCYGGGGRYEEYRGRLLDANSGGRSPDAYSGGHDSSSQSNRYGGGGRYEEYRGHSL 716
Query: 80 RSSLGGR--DLYRSGYGFNEPEQSRFGGSYGGRFESSYRNSLDSFGGRNQGGSSWEAPYS 137
++ GGR D Y G+ + S YGG S NS GG +
Sbjct: 717 DANSGGRSPDTYSRGH-----DSSSQSDHYGGGGRSLDANSSGRLPDAYSGGHDSSSRSH 771
Query: 138 RSKLRPGFMEDRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRNYDAFGGPS 197
R + E RGR S GR AY G N + P
Sbjct: 772 RYGGGGRYEEYRGRS---------------LDANSGGRSPNAYS----GGHNSSSRNDPC 812
Query: 198 TGRGR---GRGHMGDFGS-IHRPGIVVDYQNKSTN 228
G GR RGH D S H P ++ S+N
Sbjct: 813 RGGGRYEENRGHSLDANSGGHSPNAYSGGRDSSSN 847
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 52.0 bits (123), Expect = 2e-06
Identities = 80/346 (23%), Positives = 139/346 (40%), Gaps = 50/346 (14%)
Query: 253 IKKPKLAKPMEKISLSKSPTKTDPKNEEEEKRRI-EARREKQRRRREKNSEKYGDGYRMA 311
IK P+ EK+ K D K +E++ R+ E RE +RR+R + + D R
Sbjct: 85 IKPPQQMSRKEKVHHRK-----DEKRKEKKHARVKEKEREHERRKRHREEQ---DKARRE 136
Query: 312 FTCSFCKFRTFEEKDIELHLESSSHQ-ETLDHIQKQTKFDKVVMEFLHECMVNKFKKTSI 370
+ +K E+ E S + + L+ ++++ + ++ + E E K ++
Sbjct: 137 WE---------RQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERER-- 185
Query: 371 RKQQTNNQTEVVKIIEKDVMEGVTVDDHMMKVETVHCSACSVYIPALHSSVQQHLKSPDH 430
R ++ + E + E +D+ KV+ H S P ++ + D
Sbjct: 186 RAEERRKEREARR--EVSAHHRTMREDYSDKVKASHWSRSPPRPP------RERFELGD- 236
Query: 431 IKGKQAYKEQIKRESVLTATSILNNPIVKARYERFVKGENPFEIQDHSQDQQIEGDEEDE 490
G++ KE+ E L + I + + + E S++++ E +EE+E
Sbjct: 237 --GRKPVKEEKMEERDLLSDL---QDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 291
Query: 491 EKIDEPIEEEEDEDEEEEAEEVG---------EVEEVEEVEEVREGGIEGEGNIQGVGE- 540
E EEE+E+EEEE EE G EEV E E + E E ++ V E
Sbjct: 292 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES 351
Query: 541 -----GGEVGVVGEVEGVGEVEEVEELEEETAKEEPADFPVEQPEE 581
GE E G G + E + + PA P+E +E
Sbjct: 352 RFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQE 397
Score = 31.2 bits (69), Expect = 2.7
Identities = 16/51 (31%), Positives = 30/51 (58%), Gaps = 3/51 (5%)
Query: 485 GDEEDEEKI---DEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGGIEGE 532
GDE+D K+ DE ++E++ E+EE E+ ++ ++ + R+ EGE
Sbjct: 2 GDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGE 52
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 52.0 bits (123), Expect = 2e-06
Identities = 80/346 (23%), Positives = 139/346 (40%), Gaps = 50/346 (14%)
Query: 253 IKKPKLAKPMEKISLSKSPTKTDPKNEEEEKRRI-EARREKQRRRREKNSEKYGDGYRMA 311
IK P+ EK+ K D K +E++ R+ E RE +RR+R + + D R
Sbjct: 51 IKPPQQMSRKEKVHHRK-----DEKRKEKKHARVKEKEREHERRKRHREEQ---DKARRE 102
Query: 312 FTCSFCKFRTFEEKDIELHLESSSHQ-ETLDHIQKQTKFDKVVMEFLHECMVNKFKKTSI 370
+ +K E+ E S + + L+ ++++ + ++ + E E K ++
Sbjct: 103 WE---------RQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERER-- 151
Query: 371 RKQQTNNQTEVVKIIEKDVMEGVTVDDHMMKVETVHCSACSVYIPALHSSVQQHLKSPDH 430
R ++ + E + E +D+ KV+ H S P ++ + D
Sbjct: 152 RAEERRKEREARR--EVSAHHRTMREDYSDKVKASHWSRSPPRPP------RERFELGD- 202
Query: 431 IKGKQAYKEQIKRESVLTATSILNNPIVKARYERFVKGENPFEIQDHSQDQQIEGDEEDE 490
G++ KE+ E L + I + + + E S++++ E +EE+E
Sbjct: 203 --GRKPVKEEKMEERDLLSDL---QDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 257
Query: 491 EKIDEPIEEEEDEDEEEEAEEVG---------EVEEVEEVEEVREGGIEGEGNIQGVGE- 540
E EEE+E+EEEE EE G EEV E E + E E ++ V E
Sbjct: 258 EGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPES 317
Query: 541 -----GGEVGVVGEVEGVGEVEEVEELEEETAKEEPADFPVEQPEE 581
GE E G G + E + + PA P+E +E
Sbjct: 318 RFDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALSPIELKQE 363
>gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo
sapiens]
Length = 378
Score = 52.0 bits (123), Expect = 2e-06
Identities = 61/194 (31%), Positives = 67/194 (34%), Gaps = 37/194 (19%)
Query: 21 GMDRDYGPGSYGGMDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGGGGSRFGPYESYDSR 80
G R G GS M R G GG G + GGGGGSR G Y D
Sbjct: 211 GSQRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFG---GRGGYGGGGGGSR-GSYGGGDGG 266
Query: 81 --------SSLGGRDLY--RSGYGFNEPEQSRFGGSYGGRFESSYRNSLDSFGGRNQGGS 130
+ GG Y R GYG P GG YGG N +FGG N GG
Sbjct: 267 YNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGYDGYNEGGNFGGGNYGGG 326
Query: 131 SWEAPYSRSKLRPGFMEDRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRNY 190
G D G NYS + MK G R G+P +GS
Sbjct: 327 -------------GNYNDFG--NYSGQQQSNYGPMKGGSFGGRSSGSPY--GGGYGS--- 366
Query: 191 DAFGGPSTGRGRGR 204
GG S G G R
Sbjct: 367 ---GGGSGGYGSRR 377
Score = 47.8 bits (112), Expect = 3e-05
Identities = 42/126 (33%), Positives = 50/126 (39%), Gaps = 28/126 (22%)
Query: 16 YQGFNGMDRDYG-------PGSYGGMDRDYGH--GSYGGQRSMDSY-LNQSYGMDNHSGG 65
Y GF G +YG G YGG YG+ G YGG D Y ++G N+ GG
Sbjct: 267 YNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGYDGYNEGGNFGGGNYGGG 326
Query: 66 GGGSRFGPYESYDSRSSLGGRDLYRSGYGFNEPEQSRFGGSYGGRFESS-YRNSLDSFGG 124
G + FG Y +S YG GGS+GGR S Y S GG
Sbjct: 327 GNYNDFGNYSGQQ-----------QSNYG------PMKGGSFGGRSSGSPYGGGYGSGGG 369
Query: 125 RNQGGS 130
GS
Sbjct: 370 SGGYGS 375
Score = 31.6 bits (70), Expect = 2.1
Identities = 23/71 (32%), Positives = 28/71 (39%), Gaps = 16/71 (22%)
Query: 16 YQGFNGMDRDYGPGSYGGMDRDYGHGSYGGQ---------------RSMDSYLNQSYGMD 60
Y G+N ++G G+YGG G+Y GQ RS S YG
Sbjct: 309 YDGYNE-GGNFGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSGSPYGGGYGSG 367
Query: 61 NHSGGGGGSRF 71
SGG G RF
Sbjct: 368 GGSGGYGSRRF 378
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 51.2 bits (121), Expect = 3e-06
Identities = 79/345 (22%), Positives = 136/345 (39%), Gaps = 49/345 (14%)
Query: 253 IKKPKLAKPMEKISLSKSPTKTDPKNEEEEKRRIEARREKQRRRREKNSEKYGDGYRMAF 312
IK P+ EK+ K D K +E+ K RE +RR+R + + D R +
Sbjct: 85 IKPPQQMSRKEKVHHRK-----DEKRKEKWKHARVKEREHERRKRHREEQ---DKARREW 136
Query: 313 TCSFCKFRTFEEKDIELHLESSSHQ-ETLDHIQKQTKFDKVVMEFLHECMVNKFKKTSIR 371
+K E+ E S + + L+ ++++ + ++ + E E K ++ R
Sbjct: 137 E---------RQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERER--R 185
Query: 372 KQQTNNQTEVVKIIEKDVMEGVTVDDHMMKVETVHCSACSVYIPALHSSVQQHLKSPDHI 431
++ + E + E +D+ KV+ H S P ++ + D
Sbjct: 186 AEERRKEREARR--EVSAHHRTMREDYSDKVKASHWSRSPPRPP------RERFELGD-- 235
Query: 432 KGKQAYKEQIKRESVLTATSILNNPIVKARYERFVKGENPFEIQDHSQDQQIEGDEEDEE 491
G++ KE+ E L + I + + + E S++++ E +EE+EE
Sbjct: 236 -GRKPVKEEKMEERDLLSDL---QDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE 291
Query: 492 KIDEPIEEEEDEDEEEEAEEVG---------EVEEVEEVEEVREGGIEGEGNIQGVGE-- 540
EEE+E+EEEE EE G EEV E E + E E ++ V E
Sbjct: 292 GSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESR 351
Query: 541 ----GGEVGVVGEVEGVGEVEEVEELEEETAKEEPADFPVEQPEE 581
GE E G G + E + + PA P+E +E
Sbjct: 352 FDRDSGESEEAEEEVGEGTPQSSALTEGDYVPDSPALLPIELKQE 396
Score = 31.2 bits (69), Expect = 2.7
Identities = 16/51 (31%), Positives = 30/51 (58%), Gaps = 3/51 (5%)
Query: 485 GDEEDEEKI---DEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGGIEGE 532
GDE+D K+ DE ++E++ E+EE E+ ++ ++ + R+ EGE
Sbjct: 2 GDEKDSWKVKTLDEILQEKKRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGE 52
>gi|212549553 interleukin enhancer binding factor 3 isoform d [Homo
sapiens]
Length = 898
Score = 50.8 bits (120), Expect = 3e-06
Identities = 54/205 (26%), Positives = 80/205 (39%), Gaps = 37/205 (18%)
Query: 32 GGMDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGGGGSRFGPYESYDSRSSLG------- 84
GG R G G G + Y+N G ++ GG + G + Y + G
Sbjct: 649 GGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGG 708
Query: 85 -------GRDLYRSGYGFNEPEQSRFGGS---YGGRFESSYRNSLDSFGGRNQGGSSWEA 134
G Y G +N P + G +GG+ + SY + S G+ Q S ++
Sbjct: 709 GGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQ--SYNQS 766
Query: 135 PYSRSKLRPGFME--DRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRNYDA 192
PYS G + + G+ +YS +S++SP G G+ ES F NY
Sbjct: 767 PYSNYGPPQGKQKGYNHGQGSYSYSNSYNSP--------GGGGGSDYNYESKF---NYSG 815
Query: 193 FGGPSTGRGRGRGHMGDFGSIHRPG 217
GG S G G G G+ + PG
Sbjct: 816 SGGRSGGNSYGSG-----GASYNPG 835
Score = 46.2 bits (108), Expect = 8e-05
Identities = 51/181 (28%), Positives = 65/181 (35%), Gaps = 44/181 (24%)
Query: 16 YQGFNGMDRDYGPGSYG------GMDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGGGGS 69
YQ G + Y Y G + Y HG G +SY N GGGGGS
Sbjct: 753 YQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQ-GSYSYSNSY--------NSPGGGGGS 803
Query: 70 RFGPYESYDSRSSLGGRDLYRSGYGFNEPEQSRFGGSYGGRFESSYRNSLDSFGGRNQGG 129
+ YES + S GGR SG G SYG S S +GG + GG
Sbjct: 804 DYN-YESKFNYSGSGGR----SG-----------GNSYGSGGASYNPGSHGGYGGGSGGG 847
Query: 130 SSWEAPYSRSKLRPGFMEDRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRN 189
SS++ +G + S+Y+S S P S Y + S N
Sbjct: 848 SSYQG-------------KQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMN 894
Query: 190 Y 190
Y
Sbjct: 895 Y 895
Score = 38.5 bits (88), Expect = 0.017
Identities = 28/85 (32%), Positives = 38/85 (44%), Gaps = 11/85 (12%)
Query: 6 DYTHSACRNTYQGFNGMDRDYGPGSYGGMDRDYGHGSYGGQRSMDSYLNQ--SYGMDNHS 63
+Y+ S R+ + Y PGS+GG YG GS GG SY + Y N++
Sbjct: 812 NYSGSGGRSGGNSYGSGGASYNPGSHGG----YGGGSGGG----SSYQGKQGGYSQSNYN 863
Query: 64 GGGGGSRF-GPYESYDSRSSLGGRD 87
G G + GP SY S GR+
Sbjct: 864 SPGSGQNYSGPPSSYQSSQGGYGRN 888
>gi|24234750 interleukin enhancer binding factor 3 isoform a [Homo
sapiens]
Length = 894
Score = 50.8 bits (120), Expect = 3e-06
Identities = 54/205 (26%), Positives = 80/205 (39%), Gaps = 37/205 (18%)
Query: 32 GGMDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGGGGSRFGPYESYDSRSSLG------- 84
GG R G G G + Y+N G ++ GG + G + Y + G
Sbjct: 645 GGSIRGRGRGRGFGGANHGGYMNAGAGYGSYGYGGNSATAGYSQFYSNGGHSGNASGGGG 704
Query: 85 -------GRDLYRSGYGFNEPEQSRFGGS---YGGRFESSYRNSLDSFGGRNQGGSSWEA 134
G Y G +N P + G +GG+ + SY + S G+ Q S ++
Sbjct: 705 GGGGGSSGYGSYYQGDNYNSPVPPKHAGKKQPHGGQQKPSYGSGYQSHQGQQQ--SYNQS 762
Query: 135 PYSRSKLRPGFME--DRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRNYDA 192
PYS G + + G+ +YS +S++SP G G+ ES F NY
Sbjct: 763 PYSNYGPPQGKQKGYNHGQGSYSYSNSYNSP--------GGGGGSDYNYESKF---NYSG 811
Query: 193 FGGPSTGRGRGRGHMGDFGSIHRPG 217
GG S G G G G+ + PG
Sbjct: 812 SGGRSGGNSYGSG-----GASYNPG 831
Score = 46.2 bits (108), Expect = 8e-05
Identities = 51/181 (28%), Positives = 65/181 (35%), Gaps = 44/181 (24%)
Query: 16 YQGFNGMDRDYGPGSYG------GMDRDYGHGSYGGQRSMDSYLNQSYGMDNHSGGGGGS 69
YQ G + Y Y G + Y HG G +SY N GGGGGS
Sbjct: 749 YQSHQGQQQSYNQSPYSNYGPPQGKQKGYNHGQ-GSYSYSNSY--------NSPGGGGGS 799
Query: 70 RFGPYESYDSRSSLGGRDLYRSGYGFNEPEQSRFGGSYGGRFESSYRNSLDSFGGRNQGG 129
+ YES + S GGR SG G SYG S S +GG + GG
Sbjct: 800 DYN-YESKFNYSGSGGR----SG-----------GNSYGSGGASYNPGSHGGYGGGSGGG 843
Query: 130 SSWEAPYSRSKLRPGFMEDRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAYPESTFGSRN 189
SS++ +G + S+Y+S S P S Y + S N
Sbjct: 844 SSYQG-------------KQGGYSQSNYNSPGSGQNYSGPPSSYQSSQGGYGRNADHSMN 890
Query: 190 Y 190
Y
Sbjct: 891 Y 891
Score = 38.5 bits (88), Expect = 0.017
Identities = 28/85 (32%), Positives = 38/85 (44%), Gaps = 11/85 (12%)
Query: 6 DYTHSACRNTYQGFNGMDRDYGPGSYGGMDRDYGHGSYGGQRSMDSYLNQ--SYGMDNHS 63
+Y+ S R+ + Y PGS+GG YG GS GG SY + Y N++
Sbjct: 808 NYSGSGGRSGGNSYGSGGASYNPGSHGG----YGGGSGGG----SSYQGKQGGYSQSNYN 859
Query: 64 GGGGGSRF-GPYESYDSRSSLGGRD 87
G G + GP SY S GR+
Sbjct: 860 SPGSGQNYSGPPSSYQSSQGGYGRN 884
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.131 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,923,630
Number of Sequences: 37866
Number of extensions: 1475924
Number of successful extensions: 31002
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 566
Number of HSP's successfully gapped in prelim test: 569
Number of HSP's that attempted gapping in prelim test: 12413
Number of HSP's gapped (non-prelim): 9089
length of query: 582
length of database: 18,247,518
effective HSP length: 108
effective length of query: 474
effective length of database: 14,157,990
effective search space: 6710887260
effective search space used: 6710887260
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.