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Search of human proteins with 124028527
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|124028527 myotubularin related protein 10 [Homo sapiens]
(777 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|124028527 myotubularin related protein 10 [Homo sapiens] 1590 0.0
gi|94721263 myotubularin related protein 12 [Homo sapiens] 437 e-122
gi|224994251 myotubularin related protein 11 isoform a [Homo sap... 308 1e-83
gi|89111941 myotubularin related protein 11 isoform b [Homo sapi... 294 2e-79
gi|44680154 myotubularin-related protein 2 isoform 1 [Homo sapiens] 165 1e-40
gi|41350318 myotubularin-related protein 2 isoform 2 [Homo sapiens] 165 1e-40
gi|41350316 myotubularin-related protein 2 isoform 2 [Homo sapiens] 165 1e-40
gi|19923424 myotubularin related protein 9 [Homo sapiens] 159 7e-39
gi|28872761 myotubularin-related protein 1 [Homo sapiens] 159 9e-39
gi|4557896 myotubularin [Homo sapiens] 154 2e-37
gi|21361759 myotubularin related protein 8 [Homo sapiens] 138 2e-32
gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens] 133 5e-31
gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens] 133 5e-31
gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens] 133 5e-31
gi|134142348 myotubularin related protein 6 [Homo sapiens] 130 4e-30
gi|217272865 myotubularin related protein 4 [Homo sapiens] 130 5e-30
gi|225543474 myotubularin related protein 7 [Homo sapiens] 115 2e-25
gi|239735519 SET binding factor 1 [Homo sapiens] 114 5e-25
gi|29788755 SET binding factor 2 [Homo sapiens] 110 7e-24
gi|24432032 zinc finger protein 503 [Homo sapiens] 42 0.002
gi|9558733 transformer-2 alpha [Homo sapiens] 40 0.011
gi|4502565 calpain, small subunit 1 [Homo sapiens] 40 0.011
gi|51599151 calpain, small subunit 1 [Homo sapiens] 40 0.011
gi|59806361 hypothetical protein LOC387104 [Homo sapiens] 39 0.018
gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo sap... 39 0.018
gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo sap... 39 0.018
gi|238859557 regulatory factor X1 [Homo sapiens] 39 0.024
gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens] 38 0.031
gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 38 0.031
gi|5453936 POU class 3 homeobox 3 [Homo sapiens] 38 0.031
>gi|124028527 myotubularin related protein 10 [Homo sapiens]
Length = 777
Score = 1590 bits (4118), Expect = 0.0
Identities = 777/777 (100%), Positives = 777/777 (100%)
Query: 1 MFSLKPPKPTFRSYLLPPPQTDDKINSEPKIKKLEPVLLPGEIVVNEVNFVRKCIATDTS 60
MFSLKPPKPTFRSYLLPPPQTDDKINSEPKIKKLEPVLLPGEIVVNEVNFVRKCIATDTS
Sbjct: 1 MFSLKPPKPTFRSYLLPPPQTDDKINSEPKIKKLEPVLLPGEIVVNEVNFVRKCIATDTS 60
Query: 61 QYDLWGKLICSNFKISFITDDPMPLQKFHYRNLLLGEHDVPLTCIEQIVTVNDHKRKQKV 120
QYDLWGKLICSNFKISFITDDPMPLQKFHYRNLLLGEHDVPLTCIEQIVTVNDHKRKQKV
Sbjct: 61 QYDLWGKLICSNFKISFITDDPMPLQKFHYRNLLLGEHDVPLTCIEQIVTVNDHKRKQKV 120
Query: 121 LGPNQKLKFNPTELIIYCKDFRIVRFRFDESGPESAKKVCLAIAHYSQPTDLQLLFAFEY 180
LGPNQKLKFNPTELIIYCKDFRIVRFRFDESGPESAKKVCLAIAHYSQPTDLQLLFAFEY
Sbjct: 121 LGPNQKLKFNPTELIIYCKDFRIVRFRFDESGPESAKKVCLAIAHYSQPTDLQLLFAFEY 180
Query: 181 VGKKYHNSANKINGIPSGDGGGGGGGGNGAGGGSSQKTPLFETYSDWDREIKRTGASGWR 240
VGKKYHNSANKINGIPSGDGGGGGGGGNGAGGGSSQKTPLFETYSDWDREIKRTGASGWR
Sbjct: 181 VGKKYHNSANKINGIPSGDGGGGGGGGNGAGGGSSQKTPLFETYSDWDREIKRTGASGWR 240
Query: 241 VCSINEGYMISTCLPEYIVVPSSLADQDLKIFSHSFVGRRMPLWCWSHSNGSALVRMALI 300
VCSINEGYMISTCLPEYIVVPSSLADQDLKIFSHSFVGRRMPLWCWSHSNGSALVRMALI
Sbjct: 241 VCSINEGYMISTCLPEYIVVPSSLADQDLKIFSHSFVGRRMPLWCWSHSNGSALVRMALI 300
Query: 301 KDVLQQRKIDQRICNAITKSHPQRSDVYKSDLDKTLPNIQEVQAAFVKLKQLCVNEPFEE 360
KDVLQQRKIDQRICNAITKSHPQRSDVYKSDLDKTLPNIQEVQAAFVKLKQLCVNEPFEE
Sbjct: 301 KDVLQQRKIDQRICNAITKSHPQRSDVYKSDLDKTLPNIQEVQAAFVKLKQLCVNEPFEE 360
Query: 361 TEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESKHLSVVLQEEEGRDLSCCVASLVQVM 420
TEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESKHLSVVLQEEEGRDLSCCVASLVQVM
Sbjct: 361 TEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESKHLSVVLQEEEGRDLSCCVASLVQVM 420
Query: 421 LDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKRSEKESPLFLLFLDATWQLLEQYPAA 480
LDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKRSEKESPLFLLFLDATWQLLEQYPAA
Sbjct: 421 LDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKRSEKESPLFLLFLDATWQLLEQYPAA 480
Query: 481 FEFSETYLAVLYDSTRISLFGTFLFNSPHQRVKQSTEFAISKNIQLGDEKGLKFPSVWDW 540
FEFSETYLAVLYDSTRISLFGTFLFNSPHQRVKQSTEFAISKNIQLGDEKGLKFPSVWDW
Sbjct: 481 FEFSETYLAVLYDSTRISLFGTFLFNSPHQRVKQSTEFAISKNIQLGDEKGLKFPSVWDW 540
Query: 541 SLQFTAKDRTLFHNPFYIGKSTPCIQNGSVKSFKRTKKSYSSTLRGMPSALKNGIISDQE 600
SLQFTAKDRTLFHNPFYIGKSTPCIQNGSVKSFKRTKKSYSSTLRGMPSALKNGIISDQE
Sbjct: 541 SLQFTAKDRTLFHNPFYIGKSTPCIQNGSVKSFKRTKKSYSSTLRGMPSALKNGIISDQE 600
Query: 601 LLPRRNSLILKPKPDPAQQTDSQNSDTEQYFREWFSKPANLHGVILPRVSGTHIKLWKLC 660
LLPRRNSLILKPKPDPAQQTDSQNSDTEQYFREWFSKPANLHGVILPRVSGTHIKLWKLC
Sbjct: 601 LLPRRNSLILKPKPDPAQQTDSQNSDTEQYFREWFSKPANLHGVILPRVSGTHIKLWKLC 660
Query: 661 YFRWVPEAQISLGGSITAFHKLSLLADEVDVLSRMLRQQRSGPLEACYGELGQSRMYFNA 720
YFRWVPEAQISLGGSITAFHKLSLLADEVDVLSRMLRQQRSGPLEACYGELGQSRMYFNA
Sbjct: 661 YFRWVPEAQISLGGSITAFHKLSLLADEVDVLSRMLRQQRSGPLEACYGELGQSRMYFNA 720
Query: 721 SGPHHTDTSGTPEFLSSSFPFSPVGNLCRRSILGTPLSKFLSGAKIWLSTETLANED 777
SGPHHTDTSGTPEFLSSSFPFSPVGNLCRRSILGTPLSKFLSGAKIWLSTETLANED
Sbjct: 721 SGPHHTDTSGTPEFLSSSFPFSPVGNLCRRSILGTPLSKFLSGAKIWLSTETLANED 777
>gi|94721263 myotubularin related protein 12 [Homo sapiens]
Length = 747
Score = 437 bits (1123), Expect = e-122
Identities = 265/718 (36%), Positives = 405/718 (56%), Gaps = 73/718 (10%)
Query: 5 KPPKPTFRSYLLPPP-QTDDKINSEPKIKKLEPVLLPGEIVVNEVNFVRKCIATDTSQYD 63
K PKP+F SY+ P T++K +E K++ LLPGE ++ E + V K + D+ Q+
Sbjct: 14 KAPKPSFVSYVRPEEIHTNEKEVTE---KEVTLHLLPGEQLLCEASTVLKYVQEDSCQHG 70
Query: 64 LWGKLICSNFKISFITDDPMPLQ--KFHYRNLLLGEHDVPLTCIEQIVTVNDHKRKQKVL 121
++G+L+C++FKI+F+ DD L + ++N ++GE+D+ L C++QI V D K+K +
Sbjct: 71 VYGRLVCTDFKIAFLGDDESALDNDETQFKNKVIGENDITLHCVDQIYGVFDEKKKT-LF 129
Query: 122 GPNQKLKFNPTELIIYCKDFRIVRFRFDESGPESAKKVCLAIAHYSQ-PTDLQLLFAFEY 180
G +LK P +LII+CKD R+ +F + E K++ I H++Q P L+ LF F Y
Sbjct: 130 G---QLKKYPEKLIIHCKDLRVFQFCLRYTKEEEVKRIVSGIIHHTQAPKLLKRLFLFSY 186
Query: 181 VGKKYHNSANKINGIPSGDGGGGGGGGNGAGGGSSQKTPLFETYSDWDREIKRT-GASGW 239
+N+ T +F+T DW E++RT G +
Sbjct: 187 ATAAQNNTVTD----------------------PKNHTVMFDTLKDWCWELERTKGNMKY 224
Query: 240 RVCSINEGYMISTCLPEYIVVPSSLADQDLKIFSHSFVGRRMPLWCWSHSNGSALVRM-A 298
+ S+NEGY + LP Y VVP+ L +++++ F G +P+WCWS NGSAL++M A
Sbjct: 225 KAVSVNEGYKVCERLPAYFVVPTPLPEENVQRFQ----GHGIPIWCWSCHNGSALLKMSA 280
Query: 299 LIKD----VLQQRKIDQRICNAITKS--HPQRSDVYKSDLDKTLPNIQEVQAAFVKLKQL 352
L K+ +LQ I + + I K+ P V DL ++QE+Q A+ K KQL
Sbjct: 281 LPKEQDDGILQ---IQKSFLDGIYKTIHRPPYEIVKTEDLSSNFLSLQEIQTAYSKFKQL 337
Query: 353 CV---NEPFEETEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESKHLSVVLQEEEGRDL 409
+ + F +T+ KW S LE++ WL+ +R LK + E+ +E+++++V+L EE DL
Sbjct: 338 FLIDNSTEFWDTDIKWFSLLESSSWLDIIRRCLKKAIEITECMEAQNMNVLLLEENASDL 397
Query: 410 SCCVASLVQVMLDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKRSEKES-PLFLLFLD 468
C ++SLVQ+M+DP+ RT GFQSLIQKEWVM G+ FLDRCNHL++++KE P+FLLFLD
Sbjct: 398 CCLISSLVQLMMDPHCRTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLD 457
Query: 469 ATWQLLEQYPAAFEFSETYLAVLYDSTRISLFGTFLFNSPHQRVKQSTEFAISKNIQLGD 528
WQL+ Q+P AFEF+ETYL VL DS I +F TF FNSPHQ+ + + + Q
Sbjct: 458 CVWQLVHQHPPAFEFTETYLTVLSDSLYIPIFSTFFFNSPHQK-----DTNMGREGQDTQ 512
Query: 529 EKGLKFPSVWDWSLQFTAKDRTLFHNPFYIGKSTPCIQNGSVKSFK-RTKKSYSSTLRGM 587
K L +VWDWS+QF K +TL NP Y+ K P + G K + + ++ S L
Sbjct: 513 SKPLNLLTVWDWSVQFEPKAQTLLKNPLYVEK--PKLDKGQRKGMRFKHQRQLSLPLTQS 570
Query: 588 PSALKNGIISDQ------ELLPRRNSLILKPKPDPAQQTDSQNSDTEQYFREWFSKPANL 641
S+ K G ++ LL +R S ++ +D + +++ W SK +
Sbjct: 571 KSSPKRGFFREETDHLIKNLLGKRISKLI-------NSSDELQDNFREFYDSWHSKSTDY 623
Query: 642 HGVILPRVSGTHIKLWKLCYFRWVPEAQISLGGSITAFHKLSLLADEVDVLSRMLRQQ 699
HG++LP + G IK+W Y RW+PEAQI GG + KL + +EV L + ++
Sbjct: 624 HGLLLPHIEGPEIKVWAQRYLRWIPEAQILGGGQVATLSKLLEMMEEVQSLQEKIDER 681
>gi|224994251 myotubularin related protein 11 isoform a [Homo
sapiens]
Length = 709
Score = 308 bits (789), Expect = 1e-83
Identities = 230/679 (33%), Positives = 341/679 (50%), Gaps = 72/679 (10%)
Query: 39 LPGEIVVNEVNFVRKCIATDTSQYDLWGKLICSNFKISFITDDPMPLQKFHYRNLLLGEH 98
LPGE ++ VRK + + S G LIC+NF+++F P Q ++ L E+
Sbjct: 46 LPGEQILAWAPGVRKGLEPELS-----GTLICTNFRVTF---QPCGWQ-WNQDTPLNSEY 96
Query: 99 DVPLTCIEQIVTVNDHKRKQKVLGPNQKLKFNPTELIIYCKDFRIVRFRFDESGPE-SAK 157
D L I ++ V+ R Q +L P KF P E++I+ +DFR++R F+ G E A
Sbjct: 97 DFALVNIGRLEAVSGLSRVQ-LLRPGSLHKFIPEEILIHGRDFRLLRVGFEAGGLEPQAF 155
Query: 158 KVCLAIAHYSQPTDLQLLFAFEYVGKKYHNSANKINGIPSGDGGGGGGGGNGAGGGSSQK 217
+V +AI + N A + +GI G G G
Sbjct: 156 QVTMAIVQ----------------ARAQSNQAQQYSGITLSKAGQGSGS-------RKPP 192
Query: 218 TPLFETYSDWDREIKRTGASGWRVCSINEGYMISTCLPEYIVVPSSLADQDLK-IFSHSF 276
PL ET DW+ E K+ A GWRV ++NE + ++T LP Y VP+ + D +++ F H
Sbjct: 193 IPLMETAEDWETERKKQAARGWRVSTVNERFDVATSLPRYFWVPNRILDSEVRRAFGHFH 252
Query: 277 VGRRMPLWCWSHSNGSALVRMALIKDVLQQRKIDQRICNAITKSHPQRSDVYKSDLDKTL 336
GR P W H GS L+R K D R + ++ SDV D L
Sbjct: 253 QGRG-PRLSWHHPGGSDLLRCGGFYTASDPNKEDIRAVELMLQAG--HSDVVLVDTMDEL 309
Query: 337 PNIQEVQAAFVKLKQLCVNEPFEETEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESKH 396
P++ +VQ A ++L+ LC+ + E+KWLS+LE TRWL+YVRA L+ ++++ ++ S+
Sbjct: 310 PSLADVQLAHLRLRALCLPDS-SVAEDKWLSALEGTRWLDYVRACLRKASDISVLVTSRV 368
Query: 397 LSVVLQEEEGRDLSCCVASLVQVMLDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKRS 456
SV+LQE RDL+ ++SLVQ++ P RT+ GFQSL+Q+EWV AG+ FL R S
Sbjct: 369 RSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFLTRLGGTGAS 428
Query: 457 EKESPLFLLFLDATWQLLEQYPAAFEFSETYLAVLYDSTRISLFGTFLFNSPHQRVKQST 516
E E+P+FLLFLD WQLL+Q+PA FEFSE +L L+DS R+ TFL N+P +R KQS
Sbjct: 429 E-EAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRNTPWERGKQSG 487
Query: 517 EFAISKNI--------QLGDEKGLKFPSVWDWSLQFTAKDRTLFHNPFYIGKSTPCIQNG 568
+ + G+ L+ SVWDW L+++ F NP Y + P
Sbjct: 488 QLNSYTQVYTPGYSQPPAGNSFNLQL-SVWDWDLRYSNAQILQFQNPGYDPEHCP----- 541
Query: 569 SVKSFKRTKKSYSSTLRGMPSAL----KNGIISDQELLPRRNSLIL-----KPKPDPAQQ 619
R + S+ + G PS++ + + +L P R+S L + P PA
Sbjct: 542 -DSWLPRPQPSF--MVPGPPSSVWLFSRGALTPLNQLCPWRDSPSLLAVSSRWLPRPAIS 598
Query: 620 TDSQNSDTEQYFREWFSKPANLHGVILPRVSGTHIKLWKLCYFRWVPEAQISLGGSITAF 679
++S W + P G++LP G I+LW+ CY R PE Q+ L
Sbjct: 599 SESLADQEWGLPSHWGACPLP-PGLLLPGYLGPQIRLWRRCYLRGRPEVQMGLSAP---- 653
Query: 680 HKLSLLADEVDVLSRMLRQ 698
+S L DE+ L +LR+
Sbjct: 654 -TISGLQDELSHLQELLRK 671
>gi|89111941 myotubularin related protein 11 isoform b [Homo
sapiens]
Length = 640
Score = 294 bits (752), Expect = 2e-79
Identities = 213/624 (34%), Positives = 314/624 (50%), Gaps = 63/624 (10%)
Query: 94 LLGEHDVPLTCIEQIVTVNDHKRKQKVLGPNQKLKFNPTELIIYCKDFRIVRFRFDESGP 153
L E+D L I ++ V+ R Q +L P KF P E++I+ +DFR++R F+ G
Sbjct: 20 LNSEYDFALVNIGRLEAVSGLSRVQ-LLRPGSLHKFIPEEILIHGRDFRLLRVGFEAGGL 78
Query: 154 E-SAKKVCLAIAHYSQPTDLQLLFAFEYVGKKYHNSANKINGIPSGDGGGGGGGGNGAGG 212
E A +V +AI + N A + +GI G G G
Sbjct: 79 EPQAFQVTMAIVQ----------------ARAQSNQAQQYSGITLSKAGQGSGS------ 116
Query: 213 GSSQKTPLFETYSDWDREIKRTGASGWRVCSINEGYMISTCLPEYIVVPSSLADQDLK-I 271
PL ET DW+ E K+ A GWRV ++NE + ++T LP Y VP+ + D +++
Sbjct: 117 -RKPPIPLMETAEDWETERKKQAARGWRVSTVNERFDVATSLPRYFWVPNRILDSEVRRA 175
Query: 272 FSHSFVGRRMPLWCWSHSNGSALVRMALIKDVLQQRKIDQRICNAITKSHPQRSDVYKSD 331
F H GR P W H GS L+R K D R + ++ SDV D
Sbjct: 176 FGHFHQGRG-PRLSWHHPGGSDLLRCGGFYTASDPNKEDIRAVELMLQAG--HSDVVLVD 232
Query: 332 LDKTLPNIQEVQAAFVKLKQLCVNEPFEETEEKWLSSLENTRWLEYVRAFLKHSAELVYM 391
LP++ +VQ A ++L+ LC+ + E+KWLS+LE TRWL+YVRA L+ ++++ +
Sbjct: 233 TMDELPSLADVQLAHLRLRALCLPDS-SVAEDKWLSALEGTRWLDYVRACLRKASDISVL 291
Query: 392 LESKHLSVVLQEEEGRDLSCCVASLVQVMLDPYFRTITGFQSLIQKEWVMAGYQFLDRCN 451
+ S+ SV+LQE RDL+ ++SLVQ++ P RT+ GFQSL+Q+EWV AG+ FL R
Sbjct: 292 VTSRVRSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFLTRLG 351
Query: 452 HLKRSEKESPLFLLFLDATWQLLEQYPAAFEFSETYLAVLYDSTRISLFGTFLFNSPHQR 511
SE E+P+FLLFLD WQLL+Q+PA FEFSE +L L+DS R+ TFL N+P +R
Sbjct: 352 GTGASE-EAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRNTPWER 410
Query: 512 VKQSTEFAISKNI--------QLGDEKGLKFPSVWDWSLQFTAKDRTLFHNPFYIGKSTP 563
KQS + + G+ L+ SVWDW L+++ F NP Y + P
Sbjct: 411 GKQSGQLNSYTQVYTPGYSQPPAGNSFNLQL-SVWDWDLRYSNAQILQFQNPGYDPEHCP 469
Query: 564 CIQNGSVKSFKRTKKSYSSTLRGMPSAL----KNGIISDQELLPRRNSLIL-----KPKP 614
R + S+ + G PS++ + + +L P R+S L + P
Sbjct: 470 ------DSWLPRPQPSF--MVPGPPSSVWLFSRGALTPLNQLCPWRDSPSLLAVSSRWLP 521
Query: 615 DPAQQTDSQNSDTEQYFREWFSKPANLHGVILPRVSGTHIKLWKLCYFRWVPEAQISLGG 674
PA ++S W + P G++LP G I+LW+ CY R PE Q+ L
Sbjct: 522 RPAISSESLADQEWGLPSHWGACPLP-PGLLLPGYLGPQIRLWRRCYLRGRPEVQMGLSA 580
Query: 675 SITAFHKLSLLADEVDVLSRMLRQ 698
+S L DE+ L +LR+
Sbjct: 581 P-----TISGLQDELSHLQELLRK 599
>gi|44680154 myotubularin-related protein 2 isoform 1 [Homo sapiens]
Length = 643
Score = 165 bits (418), Expect = 1e-40
Identities = 144/521 (27%), Positives = 228/521 (43%), Gaps = 103/521 (19%)
Query: 35 EPVLLPGEIV---VNEVNFVRKCIATDTSQYDLWGKLICSNFKISFITDDPMPLQKFHYR 91
EP LLPGE + +V ++ C T + G L +N+++ F +
Sbjct: 75 EPPLLPGENIKDMAKDVTYI--CPFTGAVR----GTLTVTNYRLYFKSM----------- 117
Query: 92 NLLLGEHDVPLTCIEQIVTVNDHKRKQKVLGPNQKLKFNPTELIIYCKDFRIVRFRFDES 151
E D P + +N R +K+ G + + + N L CKD R +RF
Sbjct: 118 -----ERDPPFVLDASLGVIN---RVEKIGGASSRGE-NSYGLETVCKDIRNLRFAHKPE 168
Query: 152 GPESAKKVCLAIAHYSQPTDLQL-LFAFEYVGKKYHNSANKINGIPSGDGGGGGGGGNGA 210
G + + + + Y+ P L LFAFEY N
Sbjct: 169 G-RTRRSIFENLMKYAFPVSNNLPLFAFEYKEVFPEN----------------------- 204
Query: 211 GGGSSQKTPLFETYSDWDREIKRTGA--SGWRVCSINEGYMISTCLPEYIVVPSSLADQD 268
G PL E +R G WR+ INE Y + P +VVP+++ D++
Sbjct: 205 --GWKLYDPLLE--------YRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEE 254
Query: 269 LKIFSHSFVGRRMPLWCWSHSNGSALV---RMALIKDVLQQRKIDQRICNAITKSHPQRS 325
LK + R+P+ W H A + ++ ++ K D++ AI S+ Q
Sbjct: 255 LKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSH 314
Query: 326 DVYKSDLDKT----------------------------LPNIQEVQAAFVKLKQLCVNEP 357
++ D + + NI ++ + KLK++ V
Sbjct: 315 KIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEI-VYPN 373
Query: 358 FEETEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESKHLSVVLQEEEGRDLSCCVASLV 417
EET WLS+LE+T WLE+++ L + + +ES SVV+ +G D + + SL
Sbjct: 374 IEETH--WLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLA 431
Query: 418 QVMLDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKRSEKE---SPLFLLFLDATWQLL 474
+MLD Y+RTI GF+ L++KEW+ G++F R H ++ + SP+FL F+D WQ+
Sbjct: 432 MLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMT 491
Query: 475 EQYPAAFEFSETYLAVLYDSTRISLFGTFLFNSPHQRVKQS 515
Q+P AFEF+E +L + D LFGTFL NS QR K++
Sbjct: 492 RQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKEN 532
>gi|41350318 myotubularin-related protein 2 isoform 2 [Homo sapiens]
Length = 571
Score = 165 bits (418), Expect = 1e-40
Identities = 144/521 (27%), Positives = 228/521 (43%), Gaps = 103/521 (19%)
Query: 35 EPVLLPGEIV---VNEVNFVRKCIATDTSQYDLWGKLICSNFKISFITDDPMPLQKFHYR 91
EP LLPGE + +V ++ C T + G L +N+++ F +
Sbjct: 3 EPPLLPGENIKDMAKDVTYI--CPFTGAVR----GTLTVTNYRLYFKSM----------- 45
Query: 92 NLLLGEHDVPLTCIEQIVTVNDHKRKQKVLGPNQKLKFNPTELIIYCKDFRIVRFRFDES 151
E D P + +N R +K+ G + + + N L CKD R +RF
Sbjct: 46 -----ERDPPFVLDASLGVIN---RVEKIGGASSRGE-NSYGLETVCKDIRNLRFAHKPE 96
Query: 152 GPESAKKVCLAIAHYSQPTDLQL-LFAFEYVGKKYHNSANKINGIPSGDGGGGGGGGNGA 210
G + + + + Y+ P L LFAFEY N
Sbjct: 97 G-RTRRSIFENLMKYAFPVSNNLPLFAFEYKEVFPEN----------------------- 132
Query: 211 GGGSSQKTPLFETYSDWDREIKRTGA--SGWRVCSINEGYMISTCLPEYIVVPSSLADQD 268
G PL E +R G WR+ INE Y + P +VVP+++ D++
Sbjct: 133 --GWKLYDPLLE--------YRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEE 182
Query: 269 LKIFSHSFVGRRMPLWCWSHSNGSALV---RMALIKDVLQQRKIDQRICNAITKSHPQRS 325
LK + R+P+ W H A + ++ ++ K D++ AI S+ Q
Sbjct: 183 LKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSH 242
Query: 326 DVYKSDLDKT----------------------------LPNIQEVQAAFVKLKQLCVNEP 357
++ D + + NI ++ + KLK++ V
Sbjct: 243 KIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEI-VYPN 301
Query: 358 FEETEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESKHLSVVLQEEEGRDLSCCVASLV 417
EET WLS+LE+T WLE+++ L + + +ES SVV+ +G D + + SL
Sbjct: 302 IEETH--WLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLA 359
Query: 418 QVMLDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKRSEKE---SPLFLLFLDATWQLL 474
+MLD Y+RTI GF+ L++KEW+ G++F R H ++ + SP+FL F+D WQ+
Sbjct: 360 MLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMT 419
Query: 475 EQYPAAFEFSETYLAVLYDSTRISLFGTFLFNSPHQRVKQS 515
Q+P AFEF+E +L + D LFGTFL NS QR K++
Sbjct: 420 RQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKEN 460
>gi|41350316 myotubularin-related protein 2 isoform 2 [Homo sapiens]
Length = 571
Score = 165 bits (418), Expect = 1e-40
Identities = 144/521 (27%), Positives = 228/521 (43%), Gaps = 103/521 (19%)
Query: 35 EPVLLPGEIV---VNEVNFVRKCIATDTSQYDLWGKLICSNFKISFITDDPMPLQKFHYR 91
EP LLPGE + +V ++ C T + G L +N+++ F +
Sbjct: 3 EPPLLPGENIKDMAKDVTYI--CPFTGAVR----GTLTVTNYRLYFKSM----------- 45
Query: 92 NLLLGEHDVPLTCIEQIVTVNDHKRKQKVLGPNQKLKFNPTELIIYCKDFRIVRFRFDES 151
E D P + +N R +K+ G + + + N L CKD R +RF
Sbjct: 46 -----ERDPPFVLDASLGVIN---RVEKIGGASSRGE-NSYGLETVCKDIRNLRFAHKPE 96
Query: 152 GPESAKKVCLAIAHYSQPTDLQL-LFAFEYVGKKYHNSANKINGIPSGDGGGGGGGGNGA 210
G + + + + Y+ P L LFAFEY N
Sbjct: 97 G-RTRRSIFENLMKYAFPVSNNLPLFAFEYKEVFPEN----------------------- 132
Query: 211 GGGSSQKTPLFETYSDWDREIKRTGA--SGWRVCSINEGYMISTCLPEYIVVPSSLADQD 268
G PL E +R G WR+ INE Y + P +VVP+++ D++
Sbjct: 133 --GWKLYDPLLE--------YRRQGIPNESWRITKINERYELCDTYPALLVVPANIPDEE 182
Query: 269 LKIFSHSFVGRRMPLWCWSHSNGSALV---RMALIKDVLQQRKIDQRICNAITKSHPQRS 325
LK + R+P+ W H A + ++ ++ K D++ AI S+ Q
Sbjct: 183 LKRVASFRSRGRIPVLSWIHPESQATITRCSQPMVGVSGKRSKEDEKYLQAIMDSNAQSH 242
Query: 326 DVYKSDLDKT----------------------------LPNIQEVQAAFVKLKQLCVNEP 357
++ D + + NI ++ + KLK++ V
Sbjct: 243 KIFIFDARPSVNAVANKAKGGGYESEDAYQNAELVFLDIHNIHVMRESLRKLKEI-VYPN 301
Query: 358 FEETEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESKHLSVVLQEEEGRDLSCCVASLV 417
EET WLS+LE+T WLE+++ L + + +ES SVV+ +G D + + SL
Sbjct: 302 IEETH--WLSNLESTHWLEHIKLILAGALRIADKVESGKTSVVVHCSDGWDRTAQLTSLA 359
Query: 418 QVMLDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKRSEKE---SPLFLLFLDATWQLL 474
+MLD Y+RTI GF+ L++KEW+ G++F R H ++ + SP+FL F+D WQ+
Sbjct: 360 MLMLDGYYRTIRGFEVLVEKEWLSFGHRFQLRVGHGDKNHADADRSPVFLQFIDCVWQMT 419
Query: 475 EQYPAAFEFSETYLAVLYDSTRISLFGTFLFNSPHQRVKQS 515
Q+P AFEF+E +L + D LFGTFL NS QR K++
Sbjct: 420 RQFPTAFEFNEYFLITILDHLYSCLFGTFLCNSEQQRGKEN 460
>gi|19923424 myotubularin related protein 9 [Homo sapiens]
Length = 549
Score = 159 bits (403), Expect = 7e-39
Identities = 123/469 (26%), Positives = 204/469 (43%), Gaps = 107/469 (22%)
Query: 134 LIIYCKDFRIVRFRFDESGPESAKKVCLAIAHYSQPTDLQLLFAFEYVGKKYHNSANKIN 193
+II CKDFRI++ D G E + +I S + L++ F Y
Sbjct: 69 IIIKCKDFRIIQL--DIPGMEECLNIASSIEALSTLDSITLMYPFFY------------- 113
Query: 194 GIPSGDGGGGGGGGNGAGGGSSQKTPLFETYSD-W-------DREIKRTGASGWRVCSIN 245
P+FE D W + E+ + S WR+ +N
Sbjct: 114 ------------------------RPMFEVIEDGWHSFLPEQEFELYSSATSEWRLSYVN 149
Query: 246 EGYMISTCLPEYIVVPSSLADQDLKIFSHSFVGRRMPLWCWSHS-NGSALVRMA------ 298
+ + + P + VP S+ D+ L+ + G R P+ + H NG ++R
Sbjct: 150 KEFAVCPSYPPIVTVPKSIDDEALRKVATFRHGGRFPVLSYYHKKNGMVIMRSGQPLTGT 209
Query: 299 ----------LIKDVLQQRK----IDQRICNAITKS------------HPQRSDVYKSDL 332
LI L+ K ID R N ++ +PQ ++KS
Sbjct: 210 NGRRCKEDEKLINATLRAGKRGYIIDTRSLNVAQQTRAKGGGFEQEAHYPQWRRIHKS-- 267
Query: 333 DKTLPNIQEVQAAFVKLKQLCVNEPFEETEEKWLSSLENTRWLEYVRAFLKHSAELVYML 392
+ +Q + +KL + C ++ ++WLS LE + WL +++ L + +
Sbjct: 268 ---IERYHILQESLIKLVEACNDQT--HNMDRWLSKLEASNWLTHIKEILTTACLAAQCI 322
Query: 393 ESKHLSVVLQEEEGRDLSCCVASLVQVMLDPYFRTITGFQSLIQKEWVMAGYQFLDRCNH 452
+ + S+++ EG D + V SL Q++L+P RTI GF++LI++EW+ AG+ F RC
Sbjct: 323 DREGASILIHGTEGTDSTLQVTSLAQIILEPRSRTIRGFEALIEREWLQAGHPFQQRCAQ 382
Query: 453 L----KRSEKESPLFLLFLDATWQLLEQYPAAFEFSETYLAVLYDSTRISLFGTFLFNSP 508
+ + E+P+FLLFLD WQ+L Q+P +FEF+E +L +L++ S FGTFL N+
Sbjct: 383 SAYCNTKQKWEAPVFLLFLDCVWQILRQFPCSFEFNENFLIMLFEHAYASQFGTFLGNNE 442
Query: 509 HQRVKQSTEFAISKNIQLGDEKGLKFPSVWDWSLQFTAKDRTLFHNPFY 557
+R K + K S+W W Q + + F NP +
Sbjct: 443 SERCKLKLQ--------------QKTMSLWSWVNQ--PSELSKFTNPLF 475
>gi|28872761 myotubularin-related protein 1 [Homo sapiens]
Length = 665
Score = 159 bits (402), Expect = 9e-39
Identities = 142/513 (27%), Positives = 215/513 (41%), Gaps = 108/513 (21%)
Query: 87 KFHYRNLLLGEH---DVPLTCIEQIVTVNDHKRKQKVLGPNQKLKFNPTELIIYCKDFRI 143
K +++N+ H DVPL I ++ + G + I CKD R
Sbjct: 133 KLYFKNVERDPHFILDVPLGVISRVEKIGAQSHGDNSCG-----------IEIVCKDMRN 181
Query: 144 VRFRFDESGPESAKKVCLAIAHYSQPTDLQLLFAFEYVGKKYHNSANKINGIPSGDGGGG 203
+R + + H ++ Q LFAF Y K ING
Sbjct: 182 LRLAYKQEEQSKLGIFENLNKHAFPLSNGQALFAFSYKEKF------PING--------- 226
Query: 204 GGGGNGAGGGSSQKTPLFETYSDWDREIKRTGA--SGWRVCSINEGYMISTCLPEYIVVP 261
++ Y D E KR G W++ IN Y P IVVP
Sbjct: 227 -----------------WKVY-DPVSEYKRQGLPNESWKISKINSNYEFCDTYPAIIVVP 268
Query: 262 SSLADQDLKIFSHSFVGRRMPLWCWSHSNGSALVRMA---LI----KDVLQQRKIDQRIC 314
+S+ D DL + R+P+ W H A + L+ K + K Q I
Sbjct: 269 TSVKDDDLSKVAAFRAKGRVPVLSWIHPESQATITRCSQPLVGPNDKRCKEDEKYLQTIM 328
Query: 315 NAITKSHP------QRSDVYKSDLDKT--------------------LPNIQEVQAAFVK 348
+A +SH +++ V +D +KT + NI ++ + K
Sbjct: 329 DANAQSHKLIIFDARQNSV--ADTNKTKGGGYESESAYPNAELVFLEIHNIHVMRESLRK 386
Query: 349 LKQLCVNEPFEETEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESKHLSVVLQEEEGRD 408
LK++ E +WLS+++ T WLEY+R L + + +ES SVV+ +G D
Sbjct: 387 LKEIVYPSI---DEARWLSNVDGTHWLEYIRMLLAGAVRIADKIESGKTSVVVHCSDGWD 443
Query: 409 LSCCVASLVQVMLDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKRSEKE---SPLFLL 465
+ + SL +MLD Y+RTI GF++L++KEW+ G++F R H + + SP+FL
Sbjct: 444 RTAQLTSLAMLMLDSYYRTIKGFETLVEKEWISFGHRFALRVGHGNDNHADADRSPIFLQ 503
Query: 466 FLDATWQLLEQYPAAFEFSETYLAVLYDSTRISLFGTFLFNSPHQRVKQSTEFAISKNIQ 525
F+D WQ+ Q+P+AFEF+E +L + D LFGTFL N QR K E +K I
Sbjct: 504 FVDCVWQMTRQFPSAFEFNELFLITILDHLYSCLFGTFLCNCEQQRFK---EDVYTKTIS 560
Query: 526 LGDEKGLKFPSVWDWSLQFTAKDRTLFHNPFYI 558
L WS + D F NPF++
Sbjct: 561 L-------------WSYINSQLDE--FSNPFFV 578
>gi|4557896 myotubularin [Homo sapiens]
Length = 603
Score = 154 bits (390), Expect = 2e-37
Identities = 151/562 (26%), Positives = 245/562 (43%), Gaps = 128/562 (22%)
Query: 39 LPGEIVVNEVNFVRKCIATDTSQYDLWGKLICSNFKI---SFITDDPMPLQKFHYRNLLL 95
LPGE ++ + + C + G++ +N+++ S TD + L
Sbjct: 38 LPGETLITDKEVIYICPFNGPIK----GRVYITNYRLYLRSLETDSSLIL---------- 83
Query: 96 GEHDVPLTCIEQIVTVNDHKRKQKVLGPNQKLKFNPTELIIYCKDFRIVRFRFDESGPES 155
DVPL I +I +K+ G + + N L I CKD R +RF + G S
Sbjct: 84 ---DVPLGVISRI---------EKMGGATSRGE-NSYGLDITCKDMRNLRFALKQEG-HS 129
Query: 156 AKKVCLAIAHYSQPTDLQL-LFAFEYVGKKYHNSANKINGIPSGDGGGGGGGGNGAGGGS 214
+ + + Y+ P L LFAF K + N +
Sbjct: 130 RRDMFEILTRYAFPLAHSLPLFAFLNEEKFNVDGWTVYNPV------------------- 170
Query: 215 SQKTPLFETYSDWDREIKRTGASG--WRVCSINEGYMISTCLPEYIVVPSSLADQDLKIF 272
E +R G WR+ IN+ Y + P +VVP +D DL+
Sbjct: 171 --------------EEYRRQGLPNHHWRITFINKCYELCDTYPALLVVPYRASDDDLRRV 216
Query: 273 SHSFVGRRMPLWCWSH-SNGSALVRMA--LIKDVLQQRKIDQRICNAITKSHPQRSDV-- 327
+ R+P+ W H N + +VR + L+ ++ K D++ + I +++ Q S +
Sbjct: 217 ATFRSRNRIPVLSWIHPENKTVIVRCSQPLVGMSGKRNKDDEKYLDVIRETNKQISKLTI 276
Query: 328 ------------------YKSD----------LDKTLPNIQEVQAAFVKLKQLCVNEPFE 359
Y+SD LD + NI ++ + K+K + P
Sbjct: 277 YDARPSVNAVANKATGGGYESDDAYHNAELFFLD--IHNIHVMRESLKKVKDIVY--PNV 332
Query: 360 ETEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESKHLSVVLQEEEGRDLSCCVASLVQV 419
E E WLSSLE+T WLE+++ L + ++ + S SV++ +G D + + SL +
Sbjct: 333 E-ESHWLSSLESTHWLEHIKLVLTGAIQVADKVSSGKSSVLVHCSDGWDRTAQLTSLAML 391
Query: 420 MLDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKRSEKE---SPLFLLFLDATWQLLEQ 476
MLD ++R+I GF+ L+QKEW+ G++F R H ++ + SP+FL F+D WQ+ +Q
Sbjct: 392 MLDSFYRSIEGFEILVQKEWISFGHKFASRIGHGDKNHTDADRSPIFLQFIDCVWQMSKQ 451
Query: 477 YPAAFEFSETYLAVLYDSTRISLFGTFLFNSPHQRVKQS-TEFAISKNIQLGDEKGLKFP 535
+P AFEF+E +L ++ D FGTFLFN R +Q TE +S
Sbjct: 452 FPTAFEFNEQFLIIILDHLYSCRFGTFLFNCESARERQKVTERTVSL------------- 498
Query: 536 SVWDWSLQFTAKDRTLFHNPFY 557
WSL + K++ F NPFY
Sbjct: 499 ----WSLINSNKEK--FKNPFY 514
Score = 31.2 bits (69), Expect = 3.8
Identities = 15/43 (34%), Positives = 24/43 (55%), Gaps = 2/43 (4%)
Query: 624 NSDTEQYFREWFSKPANLHGVILPRVSGTHIKLWKLCYFRWVP 666
NS+ E++ +++K N V+ P S H++LW Y RW P
Sbjct: 503 NSNKEKFKNPFYTKEINR--VLYPVASMRHLELWVNYYIRWNP 543
>gi|21361759 myotubularin related protein 8 [Homo sapiens]
Length = 704
Score = 138 bits (348), Expect = 2e-32
Identities = 120/457 (26%), Positives = 196/457 (42%), Gaps = 80/457 (17%)
Query: 134 LIIYCKDFRIVRFRFDESGPESAKKVCLAIAHYSQPTDLQLLFAFEYVGKKYHNSANKIN 193
L + CK+FR+ F D +V +++ SQP + L+AF Y K
Sbjct: 70 LTLRCKNFRVAHFVLDSD--LVCHEVYISLLKLSQPALPEDLYAFSYNPKSSKEMRE--- 124
Query: 194 GIPSGDGGGGGGGGNGAGGGSSQKTPLFETYSDWDREIKRTGASGWRVCSINEGYMISTC 253
S K L + SD+ R W + N Y I +
Sbjct: 125 --------------------SGWK--LIDPISDFGR--MGIPNRNWTITDANRNYEICST 160
Query: 254 LPEYIVVPSSLADQDLKIFSHSFVGRRMPLWCWSH-SNGSALVRMALIKDVLQQRKI-DQ 311
P IVVP S+ + S R+P+ + + N +A+ R + R + D+
Sbjct: 161 YPPEIVVPKSVTLGTVVGSSKFRSKERVPVLSYLYKENNAAICRCSQPLSGFYTRCVDDE 220
Query: 312 RICNAITKSHPQRSDVYKSDLDKTL----------------------------PNIQEVQ 343
+ AI++++P +Y D L NI ++
Sbjct: 221 LLLEAISQTNPGSQFMYVVDTRPKLNAMANRAAGKGYENEDNYANIRFRFMGIENIHVMR 280
Query: 344 AAFVKLKQLCVNEPFEETEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESKHLSVVLQE 403
++ KL ++C E T ++LS LE++ WL +++A + + ++ + SV++
Sbjct: 281 SSLQKLLEVC--ELKTPTMSEFLSGLESSGWLRHIKAIMDAGIFITKAVKVEKASVLVHC 338
Query: 404 EEGRDLSCCVASLVQVMLDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKRSEKE-SPL 462
+G D + V S+ ++LDP++RT G LI+KEW+ G++F RC HL KE SP+
Sbjct: 339 SDGWDRTAQVCSVASILLDPFYRTFKGLMILIEKEWISMGHKFSQRCGHLDGDSKEVSPI 398
Query: 463 FLLFLDATWQLLEQYPAAFEFSETYLAVLYDSTRISLFGTFLFNSPHQRVKQSTEFAISK 522
F FLD WQL+EQ+P AFEF+E +L ++D FG FL N R +
Sbjct: 399 FTQFLDCIWQLMEQFPCAFEFNENFLLEIHDHVFSCQFGNFLGNCQKDR----------E 448
Query: 523 NIQLGDEKGLKFPSVWDWSLQFTAKDRTLFHNPFYIG 559
++++ + K SVW F + + F NP Y G
Sbjct: 449 DLRVYE----KTHSVW----PFLVQRKPDFRNPLYKG 477
>gi|23510389 myotubularin-related protein 3 isoform b [Homo sapiens]
Length = 1161
Score = 133 bits (335), Expect = 5e-31
Identities = 67/185 (36%), Positives = 111/185 (60%), Gaps = 6/185 (3%)
Query: 336 LPNIQEVQAAFVKLKQLCVNEPFEETEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESK 395
+ NI ++ +F L+ LC P WLS+LE+T+WL ++ LK + +V+ ++
Sbjct: 349 MANIHSIRRSFQSLRLLCTQMP---DPGNWLSALESTKWLHHLSVLLKSALLVVHAVDQD 405
Query: 396 HLSVVLQEEEGRDLSCCVASLVQVMLDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKR 455
V++ +G D + + +L +++LDPY+RTI GFQ L++ EW+ G++F DRC H +
Sbjct: 406 QRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLVEMEWLDFGHKFADRCGHGEN 465
Query: 456 SE---KESPLFLLFLDATWQLLEQYPAAFEFSETYLAVLYDSTRISLFGTFLFNSPHQRV 512
S+ + P+FL +LD QL Q+P +FEF+E +L L T LFGTFL N+ +R
Sbjct: 466 SDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCNNAKERG 525
Query: 513 KQSTE 517
++ T+
Sbjct: 526 EKHTQ 530
>gi|23510387 myotubularin-related protein 3 isoform a [Homo sapiens]
Length = 1170
Score = 133 bits (335), Expect = 5e-31
Identities = 67/185 (36%), Positives = 111/185 (60%), Gaps = 6/185 (3%)
Query: 336 LPNIQEVQAAFVKLKQLCVNEPFEETEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESK 395
+ NI ++ +F L+ LC P WLS+LE+T+WL ++ LK + +V+ ++
Sbjct: 349 MANIHSIRRSFQSLRLLCTQMP---DPGNWLSALESTKWLHHLSVLLKSALLVVHAVDQD 405
Query: 396 HLSVVLQEEEGRDLSCCVASLVQVMLDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKR 455
V++ +G D + + +L +++LDPY+RTI GFQ L++ EW+ G++F DRC H +
Sbjct: 406 QRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLVEMEWLDFGHKFADRCGHGEN 465
Query: 456 SE---KESPLFLLFLDATWQLLEQYPAAFEFSETYLAVLYDSTRISLFGTFLFNSPHQRV 512
S+ + P+FL +LD QL Q+P +FEF+E +L L T LFGTFL N+ +R
Sbjct: 466 SDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCNNAKERG 525
Query: 513 KQSTE 517
++ T+
Sbjct: 526 EKHTQ 530
>gi|10835109 myotubularin-related protein 3 isoform c [Homo sapiens]
Length = 1198
Score = 133 bits (335), Expect = 5e-31
Identities = 67/185 (36%), Positives = 111/185 (60%), Gaps = 6/185 (3%)
Query: 336 LPNIQEVQAAFVKLKQLCVNEPFEETEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESK 395
+ NI ++ +F L+ LC P WLS+LE+T+WL ++ LK + +V+ ++
Sbjct: 349 MANIHSIRRSFQSLRLLCTQMP---DPGNWLSALESTKWLHHLSVLLKSALLVVHAVDQD 405
Query: 396 HLSVVLQEEEGRDLSCCVASLVQVMLDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKR 455
V++ +G D + + +L +++LDPY+RTI GFQ L++ EW+ G++F DRC H +
Sbjct: 406 QRPVLVHCSDGWDRTPQIVALAKLLLDPYYRTIEGFQVLVEMEWLDFGHKFADRCGHGEN 465
Query: 456 SE---KESPLFLLFLDATWQLLEQYPAAFEFSETYLAVLYDSTRISLFGTFLFNSPHQRV 512
S+ + P+FL +LD QL Q+P +FEF+E +L L T LFGTFL N+ +R
Sbjct: 466 SDDLNERCPVFLQWLDCVHQLQRQFPCSFEFNEAFLVKLVQHTYSCLFGTFLCNNAKERG 525
Query: 513 KQSTE 517
++ T+
Sbjct: 526 EKHTQ 530
>gi|134142348 myotubularin related protein 6 [Homo sapiens]
Length = 621
Score = 130 bits (328), Expect = 4e-30
Identities = 121/460 (26%), Positives = 199/460 (43%), Gaps = 82/460 (17%)
Query: 134 LIIYCKDFRIVRFRFDESGPESAKKVCLAIAHYSQPTDLQLLFAFEYVGKKYHNSANKIN 193
L+I CK+FR V F + ++ S+ + L+AF Y K+ N + ++
Sbjct: 68 LVIQCKNFRTVHFIVPRE--RDCHDIYNSLLQLSKQAKYEDLYAFSYNPKQ--NDSERLQ 123
Query: 194 GIPSGDGGGGGGGGNGAGGGSSQKTPLFETYSDWDREIKRTGA--SGWRVCSINEGYMIS 251
G Q L E Y KR G S W++ N Y I
Sbjct: 124 G--------------------WQLIDLAEEY-------KRMGVPNSHWQLSDANRDYKIC 156
Query: 252 TCLPEYIVVPSSLADQDLKIFSHSFVGR-RMPLWCWSHSN-GSALVRMALIKDVLQQRKI 309
P + VP +A + + + S F + R P+ + H + +A+ R + R +
Sbjct: 157 ETYPRELYVP-RIASKPIIVGSSKFRSKGRFPVLSYYHQDKEAAICRCSQPLSGFSARCL 215
Query: 310 -DQRICNAITKSHPQRSDVYKSDLDKTL---------------PNIQEVQAAFVKL---- 349
D+ + AI+K++P +Y D L N ++ FV +
Sbjct: 216 EDEHLLQAISKANPVNRYMYVMDTRPKLNAMANRAAGKGYENEDNYSNIRFQFVGIENIH 275
Query: 350 -------KQLCVNEPFEETEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESKHLSVVLQ 402
K L VN + + S LE++ WL +++A + + L + ++ SV++
Sbjct: 276 VMRSSLQKLLEVNGTKGLSVNDFYSGLESSGWLRHIKAVMDAAIFLAKAITVENASVLVH 335
Query: 403 EEEGRDLSCCVASLVQVMLDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKRSEKE-SP 461
+G D + V SL ++LD Y+RTI GF LI+K+W+ G++F +RC L KE SP
Sbjct: 336 CSDGWDRTSQVCSLGSLLLDSYYRTIKGFMVLIEKDWISFGHKFSERCGQLDGDPKEVSP 395
Query: 462 LFLLFLDATWQLLEQYPAAFEFSETYLAVLYDSTRISLFGTFLFNSPHQRVKQSTEFAIS 521
+F FL+ W L EQ+P AFEFSE +L +++ FG FL N +R
Sbjct: 396 VFTQFLECVWHLTEQFPQAFEFSEAFLLQIHEHIHSCQFGNFLGNCQKER---------- 445
Query: 522 KNIQLGDEKGLKFPSVWDWSLQFTAKDRTLFHNPFYIGKS 561
+ ++L + K S+W F +D+ + NP Y +S
Sbjct: 446 EELKLKE----KTYSLW----PFLLEDQKKYLNPLYSSES 477
>gi|217272865 myotubularin related protein 4 [Homo sapiens]
Length = 1195
Score = 130 bits (327), Expect = 5e-30
Identities = 64/183 (34%), Positives = 113/183 (61%), Gaps = 6/183 (3%)
Query: 336 LPNIQEVQAAFVKLKQLCVNEPFEETEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESK 395
+ NI ++ +F L+ +C P WLS+LE+T+WL+++ LK + + ++ +
Sbjct: 343 MANIHAIRNSFQYLRAVCSQMP---DPSNWLSALESTKWLQHLSVMLKAAVLVANTVDRE 399
Query: 396 HLSVVLQEEEGRDLSCCVASLVQVMLDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKR 455
V++ +G D + + +L +++LDPY+RT+ GFQ L++ +W+ G++F DRC H +
Sbjct: 400 GRPVLVHCSDGWDRTPQIVALAKILLDPYYRTLEGFQVLVESDWLDFGHKFGDRCGHQEN 459
Query: 456 SE---KESPLFLLFLDATWQLLEQYPAAFEFSETYLAVLYDSTRISLFGTFLFNSPHQRV 512
E ++ P+FL +LD+ QLL+Q+P FEF+E +L L T L+GTFL N+P +R
Sbjct: 460 VEDQNEQCPVFLQWLDSVHQLLKQFPCLFEFNEAFLVKLVQHTYSCLYGTFLANNPCERE 519
Query: 513 KQS 515
K++
Sbjct: 520 KRN 522
>gi|225543474 myotubularin related protein 7 [Homo sapiens]
Length = 660
Score = 115 bits (288), Expect = 2e-25
Identities = 85/317 (26%), Positives = 143/317 (45%), Gaps = 31/317 (9%)
Query: 226 DWDREIKRTGASG--WRVCSINEGYMISTCLPEYIVVPSSLADQDLKIFSHSFVGRRMPL 283
D E R G W++ +N Y + P + VP S + S RR P+
Sbjct: 131 DLSEEYTRMGLPNHYWQLSDVNRDYRVCDSYPTELYVPKSATAHIIVGSSKFRSRRRFPV 190
Query: 284 WCWSH-SNGSALVRMALIKDVLQQRKI-DQRICNAITKSHPQRSDVYKSDLDKTL----- 336
+ + N +++ R + R + D+++ AI K++P VY D L
Sbjct: 191 LSYYYKDNHASICRSSQPLSGFSARCLEDEQMLQAIRKANPGSDFVYVVDTRPKLNAMAN 250
Query: 337 ----------PNIQEVQAAFVKL-----------KQLCVNEPFEETEEKWLSSLENTRWL 375
N ++ F+ + K L V E + +L LEN+ WL
Sbjct: 251 RAAGKGYENEDNYSNIKFQFIGIENIHVMRNSLQKMLEVCELKSPSMSDFLWGLENSGWL 310
Query: 376 EYVRAFLKHSAELVYMLESKHLSVVLQEEEGRDLSCCVASLVQVMLDPYFRTITGFQSLI 435
+++A + + + + SV++ +G D + V S+ ++LDP++RT+ GF LI
Sbjct: 311 RHIKAIMDAGIFIAKAVSEEGASVLVHCSDGWDRTAQVCSVASLLLDPHYRTLKGFMVLI 370
Query: 436 QKEWVMAGYQFLDRCNHLKRSEKE-SPLFLLFLDATWQLLEQYPAAFEFSETYLAVLYDS 494
+K+W+ G++F R +L KE SP+ F++ WQL+EQ+P AFEF+E +L +
Sbjct: 371 EKDWISFGHKFNHRYGNLDGDPKEISPVIDQFIECVWQLMEQFPCAFEFNERFLIHIQHH 430
Query: 495 TRISLFGTFLFNSPHQR 511
FG FL NS +R
Sbjct: 431 IYSCQFGNFLCNSQKER 447
>gi|239735519 SET binding factor 1 [Homo sapiens]
Length = 1893
Score = 114 bits (284), Expect = 5e-25
Identities = 75/223 (33%), Positives = 126/223 (56%), Gaps = 12/223 (5%)
Query: 340 QEVQAAFVKLKQLCVN--EPFEETEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESKHL 397
++V+A+F KL + CV E + +L SLE++ WL + L+ S +V +L+S
Sbjct: 1383 RQVKASFKKLLKACVPGCPAAEPSPASFLRSLEDSEWLIQIHKLLQVSVLVVELLDSGS- 1441
Query: 398 SVVLQEEEGRDLSCCVASLVQVMLDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKRSE 457
SV++ E+G D++ V SLVQ++ DP++RT+ GF+ L++KEW+ G++F R H +
Sbjct: 1442 SVLVGLEDGWDITTQVVSLVQLLSDPFYRTLEGFRLLVEKEWLSFGHRFSHRGAHTLAGQ 1501
Query: 458 KE--SPLFLLFLDATWQLLEQYPAAFEFSETYLAVLYDSTRISLFGTFLFNSPHQRVKQS 515
+P+FL FLD Q+ Q+P FEFS+ YL L F TFL +S ++R++
Sbjct: 1502 SSGFTPVFLQFLDCVHQVHLQFPMEFEFSQFYLKFLGYHHVSRRFRTFLLDSDYERIELG 1561
Query: 516 TEFAISKNIQLGDEKG-LKFPSVWDWSLQFTAKDRTLFHNPFY 557
+ + G+ +G + SVW++ + +K +FHN Y
Sbjct: 1562 LLYE-----EKGERRGQVPCRSVWEY-VDRLSKRTPVFHNYMY 1598
Score = 38.1 bits (87), Expect = 0.031
Identities = 17/65 (26%), Positives = 30/65 (46%)
Query: 231 IKRTGASGWRVCSINEGYMISTCLPEYIVVPSSLADQDLKIFSHSFVGRRMPLWCWSHSN 290
+ R + +R+ +N Y I P ++VP S+ D L+ S + R P+ CW
Sbjct: 1142 LSRAKSEPFRISPVNRMYAICRSYPGLLIVPQSVQDNALQRVSRCYRQNRFPVVCWRSGR 1201
Query: 291 GSALV 295
A++
Sbjct: 1202 SKAVL 1206
>gi|29788755 SET binding factor 2 [Homo sapiens]
Length = 1849
Score = 110 bits (274), Expect = 7e-24
Identities = 77/255 (30%), Positives = 132/255 (51%), Gaps = 11/255 (4%)
Query: 339 IQEVQAAFVKLKQLCVNEPFE-ETEEKWLSSLENTRWLEYVRAFLKHSAELVYMLESKHL 397
I++V+A+F KL + C+ ++E +L +L ++ W + ++ + + +LE+
Sbjct: 1346 IRQVKASFKKLMRACIPSTIPTDSEVTFLKALGDSEWFPQLHRIMQLAVVVSEVLENGS- 1404
Query: 398 SVVLQEEEGRDLSCCVASLVQVMLDPYFRTITGFQSLIQKEWVMAGYQFLDRCNHLKRSE 457
SV++ EEG D++ V SLVQ++ DP++RT+ GFQ L++KEW+ G++F R + +
Sbjct: 1405 SVLVCLEEGWDITAQVTSLVQLLSDPFYRTLEGFQMLVEKEWLSFGHKFSQRSSLTLNCQ 1464
Query: 458 KE--SPLFLLFLDATWQLLEQYPAAFEFSETYLAVLYDSTRISLFGTFLFNSPHQRVKQS 515
+P+FL FLD Q+ QYP FEF+ YL L + F TFL +S ++R++
Sbjct: 1465 GSGFAPVFLQFLDCVHQVHNQYPTEFEFNLYYLKFLAFHYVSNRFKTFLLDSDYERLEHG 1524
Query: 516 TEFAISKNIQLGDEKGLKFPSVWDWSLQFTAKDRTLFHNPFYIGKSTPCIQ-NGSVKSFK 574
T F G++ K +W+ + K +F N Y ++ N +V S K
Sbjct: 1525 TLFD-----DKGEKHAKKGVCIWE-CIDRMHKRSPIFFNYLYSPLEIEALKPNVNVSSLK 1578
Query: 575 RTKKSYSSTLRGMPS 589
+ TL PS
Sbjct: 1579 KWDYYIEETLSTGPS 1593
Score = 40.8 bits (94), Expect = 0.005
Identities = 37/153 (24%), Positives = 61/153 (39%), Gaps = 3/153 (1%)
Query: 239 WRVCSINEGYMISTCLPEYIVVPSSLADQDLKIFSHSFVGRRMPLWCWSHS-NGSALVRM 297
+R+ + N Y + P +VVP ++ D L + + R+P+ CW +S +G+ L+R
Sbjct: 1138 FRITASNRMYSLCRSYPGLLVVPQAVQDSSLPRVARCYRHNRLPVVCWKNSRSGTLLLRS 1197
Query: 298 ALI--KDVLQQRKIDQRICNAITKSHPQRSDVYKSDLDKTLPNIQEVQAAFVKLKQLCVN 355
K V+ K A T S S + + + L N V L V
Sbjct: 1198 GGFHGKGVVGLFKSQNSPQAAPTSSLESSSSIEQEKYLQALLNAVSVHQKLRGNSTLTVR 1257
Query: 356 EPFEETEEKWLSSLENTRWLEYVRAFLKHSAEL 388
F + W S +TR + +F+ A L
Sbjct: 1258 PAFALSPGVWASLRSSTRLISSPTSFIDVGARL 1290
>gi|24432032 zinc finger protein 503 [Homo sapiens]
Length = 646
Score = 42.4 bits (98), Expect = 0.002
Identities = 22/57 (38%), Positives = 30/57 (52%)
Query: 196 PSGDGGGGGGGGNGAGGGSSQKTPLFETYSDWDREIKRTGASGWRVCSINEGYMIST 252
P G GGGGGGGG G GG SS+K+ + RTG+ + + G M+S+
Sbjct: 188 PGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLSS 244
Score = 35.0 bits (79), Expect = 0.27
Identities = 20/70 (28%), Positives = 31/70 (44%), Gaps = 12/70 (17%)
Query: 181 VGKKYHNSANKINGIPSGDGGGGGGGGNGAGGGSSQKTPL------------FETYSDWD 228
+GK + ++K++ + S GG GG GG AG ++ PL F+ YS
Sbjct: 123 IGKPDPSPSSKLSSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPG 182
Query: 229 REIKRTGASG 238
+ K G G
Sbjct: 183 SDKKEPGGGG 192
>gi|9558733 transformer-2 alpha [Homo sapiens]
Length = 282
Score = 39.7 bits (91), Expect = 0.011
Identities = 19/53 (35%), Positives = 26/53 (49%), Gaps = 9/53 (16%)
Query: 194 GIPSGDGGGGGGGGNGAGGGSSQKTPL---------FETYSDWDREIKRTGAS 237
G P+ GGGGGGGG G GGG ++ ++ Y D+D +R S
Sbjct: 210 GRPTHSGGGGGGGGGGGGGGGGRRRDSYYDRGYDRGYDRYEDYDYRYRRRSPS 262
>gi|4502565 calpain, small subunit 1 [Homo sapiens]
Length = 268
Score = 39.7 bits (91), Expect = 0.011
Identities = 16/24 (66%), Positives = 18/24 (75%)
Query: 190 NKINGIPSGDGGGGGGGGNGAGGG 213
N + G+ SG GGGGGGGG G GGG
Sbjct: 27 NVLGGLISGAGGGGGGGGGGGGGG 50
Score = 37.4 bits (85), Expect = 0.054
Identities = 15/22 (68%), Positives = 16/22 (72%)
Query: 192 INGIPSGDGGGGGGGGNGAGGG 213
I+G G GGGGGGGG G GGG
Sbjct: 33 ISGAGGGGGGGGGGGGGGGGGG 54
Score = 35.8 bits (81), Expect = 0.16
Identities = 13/20 (65%), Positives = 16/20 (80%)
Query: 198 GDGGGGGGGGNGAGGGSSQK 217
G GGGGGGGG G GGG++ +
Sbjct: 41 GGGGGGGGGGGGGGGGTAMR 60
Score = 32.0 bits (71), Expect = 2.3
Identities = 12/14 (85%), Positives = 12/14 (85%)
Query: 200 GGGGGGGGNGAGGG 213
GGGGGGGG G GGG
Sbjct: 11 GGGGGGGGGGLGGG 24
Score = 30.0 bits (66), Expect = 8.6
Identities = 12/20 (60%), Positives = 14/20 (70%)
Query: 195 IPSGDGGGGGGGGNGAGGGS 214
+ G GGGGGGGG G G G+
Sbjct: 8 LKGGGGGGGGGGGLGGGLGN 27
>gi|51599151 calpain, small subunit 1 [Homo sapiens]
Length = 268
Score = 39.7 bits (91), Expect = 0.011
Identities = 16/24 (66%), Positives = 18/24 (75%)
Query: 190 NKINGIPSGDGGGGGGGGNGAGGG 213
N + G+ SG GGGGGGGG G GGG
Sbjct: 27 NVLGGLISGAGGGGGGGGGGGGGG 50
Score = 37.4 bits (85), Expect = 0.054
Identities = 15/22 (68%), Positives = 16/22 (72%)
Query: 192 INGIPSGDGGGGGGGGNGAGGG 213
I+G G GGGGGGGG G GGG
Sbjct: 33 ISGAGGGGGGGGGGGGGGGGGG 54
Score = 35.8 bits (81), Expect = 0.16
Identities = 13/20 (65%), Positives = 16/20 (80%)
Query: 198 GDGGGGGGGGNGAGGGSSQK 217
G GGGGGGGG G GGG++ +
Sbjct: 41 GGGGGGGGGGGGGGGGTAMR 60
Score = 32.0 bits (71), Expect = 2.3
Identities = 12/14 (85%), Positives = 12/14 (85%)
Query: 200 GGGGGGGGNGAGGG 213
GGGGGGGG G GGG
Sbjct: 11 GGGGGGGGGGLGGG 24
Score = 30.0 bits (66), Expect = 8.6
Identities = 12/20 (60%), Positives = 14/20 (70%)
Query: 195 IPSGDGGGGGGGGNGAGGGS 214
+ G GGGGGGGG G G G+
Sbjct: 8 LKGGGGGGGGGGGLGGGLGN 27
>gi|59806361 hypothetical protein LOC387104 [Homo sapiens]
Length = 947
Score = 38.9 bits (89), Expect = 0.018
Identities = 15/22 (68%), Positives = 18/22 (81%)
Query: 196 PSGDGGGGGGGGNGAGGGSSQK 217
P G+GGGGGG G GAGGGS ++
Sbjct: 162 PLGEGGGGGGEGGGAGGGSGER 183
>gi|38683807 ankyrin repeat domain protein 17 isoform a [Homo
sapiens]
Length = 2603
Score = 38.9 bits (89), Expect = 0.018
Identities = 18/35 (51%), Positives = 21/35 (60%)
Query: 197 SGDGGGGGGGGNGAGGGSSQKTPLFETYSDWDREI 231
SG GGGGGGGG G GG SS + E D + E+
Sbjct: 95 SGGGGGGGGGGGGGGGTSSNNSEEEEDDDDEEEEV 129
Score = 36.6 bits (83), Expect = 0.091
Identities = 17/43 (39%), Positives = 22/43 (51%)
Query: 188 SANKINGIPSGDGGGGGGGGNGAGGGSSQKTPLFETYSDWDRE 230
S+++ + GGGGGGGG G GGG + E D D E
Sbjct: 84 SSSESSSDSDNSGGGGGGGGGGGGGGGTSSNNSEEEEDDDDEE 126
Score = 35.8 bits (81), Expect = 0.16
Identities = 17/44 (38%), Positives = 23/44 (52%)
Query: 187 NSANKINGIPSGDGGGGGGGGNGAGGGSSQKTPLFETYSDWDRE 230
+S+ + + GGGGGGGG G GGG+S E D + E
Sbjct: 84 SSSESSSDSDNSGGGGGGGGGGGGGGGTSSNNSEEEEDDDDEEE 127
>gi|38683816 ankyrin repeat domain protein 17 isoform b [Homo
sapiens]
Length = 2352
Score = 38.9 bits (89), Expect = 0.018
Identities = 18/35 (51%), Positives = 21/35 (60%)
Query: 197 SGDGGGGGGGGNGAGGGSSQKTPLFETYSDWDREI 231
SG GGGGGGGG G GG SS + E D + E+
Sbjct: 95 SGGGGGGGGGGGGGGGTSSNNSEEEEDDDDEEEEV 129
Score = 36.6 bits (83), Expect = 0.091
Identities = 17/43 (39%), Positives = 22/43 (51%)
Query: 188 SANKINGIPSGDGGGGGGGGNGAGGGSSQKTPLFETYSDWDRE 230
S+++ + GGGGGGGG G GGG + E D D E
Sbjct: 84 SSSESSSDSDNSGGGGGGGGGGGGGGGTSSNNSEEEEDDDDEE 126
Score = 35.8 bits (81), Expect = 0.16
Identities = 17/44 (38%), Positives = 23/44 (52%)
Query: 187 NSANKINGIPSGDGGGGGGGGNGAGGGSSQKTPLFETYSDWDRE 230
+S+ + + GGGGGGGG G GGG+S E D + E
Sbjct: 84 SSSESSSDSDNSGGGGGGGGGGGGGGGTSSNNSEEEEDDDDEEE 127
>gi|238859557 regulatory factor X1 [Homo sapiens]
Length = 979
Score = 38.5 bits (88), Expect = 0.024
Identities = 24/70 (34%), Positives = 29/70 (41%), Gaps = 17/70 (24%)
Query: 188 SANKINGIPSGDGGGGGGGGNGAGGGSSQKTPLFETYSDWDREIKRTGASGWRVCSINEG 247
++N G SG GGGGGGGG G G GS+ G SG I G
Sbjct: 376 ASNSSGGGGSGGGGGGGGGGGGGGSGST-----------------GGGGSGAGTYVIQGG 418
Query: 248 YMISTCLPEY 257
YM+ + Y
Sbjct: 419 YMLGSASQSY 428
>gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]
Length = 391
Score = 38.1 bits (87), Expect = 0.031
Identities = 19/44 (43%), Positives = 25/44 (56%), Gaps = 7/44 (15%)
Query: 196 PSGDGGGGGGGGNGAGGGSSQ------KTPLFETYSDWDREIKR 233
P+G GGGGGGGG G GGG ++ K P+ + W R +R
Sbjct: 25 PAGAGGGGGGGGGGGGGGGAKANQDRVKRPM-NAFMVWSRGQRR 67
>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
Length = 3703
Score = 38.1 bits (87), Expect = 0.031
Identities = 15/34 (44%), Positives = 20/34 (58%)
Query: 180 YVGKKYHNSANKINGIPSGDGGGGGGGGNGAGGG 213
+ G+ N + +P+G GGGG GGG G GGG
Sbjct: 3489 FFGQSVVNLQEMVLHVPTGGGGGGSGGGGGGGGG 3522
Score = 36.2 bits (82), Expect = 0.12
Identities = 14/17 (82%), Positives = 14/17 (82%)
Query: 198 GDGGGGGGGGNGAGGGS 214
G GGGGGGGG G GGGS
Sbjct: 3512 GSGGGGGGGGGGGGGGS 3528
>gi|5453936 POU class 3 homeobox 3 [Homo sapiens]
Length = 500
Score = 38.1 bits (87), Expect = 0.031
Identities = 16/26 (61%), Positives = 16/26 (61%)
Query: 194 GIPSGDGGGGGGGGNGAGGGSSQKTP 219
G G GGGGGGGG GAGGG P
Sbjct: 28 GAGGGGGGGGGGGGGGAGGGGGGMQP 53
Score = 35.8 bits (81), Expect = 0.16
Identities = 16/32 (50%), Positives = 17/32 (53%)
Query: 182 GKKYHNSANKINGIPSGDGGGGGGGGNGAGGG 213
G H+ A G G GGGGGGG G GGG
Sbjct: 19 GSIVHSDAAGAGGGGGGGGGGGGGGAGGGGGG 50
Score = 34.7 bits (78), Expect = 0.35
Identities = 13/18 (72%), Positives = 15/18 (83%)
Query: 197 SGDGGGGGGGGNGAGGGS 214
+G GGGGGGGG G GGG+
Sbjct: 27 AGAGGGGGGGGGGGGGGA 44
Score = 30.8 bits (68), Expect = 5.0
Identities = 13/28 (46%), Positives = 16/28 (57%)
Query: 188 SANKINGIPSGDGGGGGGGGNGAGGGSS 215
+A I + GGGGGGG G GGG +
Sbjct: 17 AAGSIVHSDAAGAGGGGGGGGGGGGGGA 44
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.136 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,957,445
Number of Sequences: 37866
Number of extensions: 1542445
Number of successful extensions: 13333
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 191
Number of HSP's successfully gapped in prelim test: 35
Number of HSP's that attempted gapping in prelim test: 8948
Number of HSP's gapped (non-prelim): 2753
length of query: 777
length of database: 18,247,518
effective HSP length: 110
effective length of query: 667
effective length of database: 14,082,258
effective search space: 9392866086
effective search space used: 9392866086
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.