Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 122937412
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|122937412 ubiquitin specific peptidase 45 [Homo sapiens]
(814 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|122937412 ubiquitin specific peptidase 45 [Homo sapiens] 1635 0.0
gi|50312664 ubiquitin specific protease 16 isoform b [Homo sapiens] 553 e-157
gi|5454156 ubiquitin specific protease 16 isoform a [Homo sapiens] 552 e-157
gi|75992941 ubiquitin specific protease 16 isoform a [Homo sapiens] 552 e-157
gi|42516561 ubiquitin specific protease 33 isoform 3 [Homo sapiens] 134 3e-31
gi|42516567 ubiquitin specific protease 33 isoform 1 [Homo sapiens] 132 1e-30
gi|42516565 ubiquitin specific protease 33 isoform 2 [Homo sapiens] 132 2e-30
gi|40795665 ubiquitin specific protease 4 isoform a [Homo sapiens] 127 4e-29
gi|40795667 ubiquitin specific protease 4 isoform b [Homo sapiens] 127 4e-29
gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens] 94 5e-19
gi|109134334 ubiquitin thiolesterase 44 [Homo sapiens] 89 2e-17
gi|109134332 ubiquitin thiolesterase 44 [Homo sapiens] 89 2e-17
gi|41152235 ubiquitin specific protease 51 [Homo sapiens] 88 4e-17
gi|63053524 ubiquitin specific protease 1 [Homo sapiens] 86 1e-16
gi|63053522 ubiquitin specific protease 1 [Homo sapiens] 86 1e-16
gi|31543910 ubiquitin specific protease 1 [Homo sapiens] 86 1e-16
gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens] 82 3e-15
gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo sapi... 82 3e-15
gi|57529246 ubiquitin thioesterase 19 [Homo sapiens] 81 3e-15
gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens] 80 8e-15
gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens] 79 2e-14
gi|24234683 ubiquitin specific peptidase 11 [Homo sapiens] 79 2e-14
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens] 78 3e-14
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens] 78 3e-14
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens] 78 3e-14
gi|183396780 ubiquitin specific protease 20 [Homo sapiens] 78 4e-14
gi|183397136 ubiquitin specific protease 20 [Homo sapiens] 78 4e-14
gi|183397134 ubiquitin specific protease 20 [Homo sapiens] 78 4e-14
gi|14149627 ubiquitin specific peptidase 15 [Homo sapiens] 77 5e-14
gi|122114651 ubiquitin specific peptidase 36 [Homo sapiens] 75 2e-13
>gi|122937412 ubiquitin specific peptidase 45 [Homo sapiens]
Length = 814
Score = 1635 bits (4235), Expect = 0.0
Identities = 814/814 (100%), Positives = 814/814 (100%)
Query: 1 MRVKDPTKALPEKAKRSKRPTVPHDEDSSDDIAVGLTCQHVSHAISVNHVKRAIAENLWS 60
MRVKDPTKALPEKAKRSKRPTVPHDEDSSDDIAVGLTCQHVSHAISVNHVKRAIAENLWS
Sbjct: 1 MRVKDPTKALPEKAKRSKRPTVPHDEDSSDDIAVGLTCQHVSHAISVNHVKRAIAENLWS 60
Query: 61 VCSECLKERRFYDGQLVLTSDIWLCLKCGFQGCGKNSESQHSLKHFKSSRTEPHCIIINL 120
VCSECLKERRFYDGQLVLTSDIWLCLKCGFQGCGKNSESQHSLKHFKSSRTEPHCIIINL
Sbjct: 61 VCSECLKERRFYDGQLVLTSDIWLCLKCGFQGCGKNSESQHSLKHFKSSRTEPHCIIINL 120
Query: 121 STWIIWCYECDEKLSTHCNKKVLAQIVDFLQKHASKTQTSAFSRIMKLCEEKCETDEIQK 180
STWIIWCYECDEKLSTHCNKKVLAQIVDFLQKHASKTQTSAFSRIMKLCEEKCETDEIQK
Sbjct: 121 STWIIWCYECDEKLSTHCNKKVLAQIVDFLQKHASKTQTSAFSRIMKLCEEKCETDEIQK 180
Query: 181 GGKCRNLSVRGITNLGNTCFFNAVMQNLAQTYTLTDLMNEIKESSTKLKIFPSSDSQLDP 240
GGKCRNLSVRGITNLGNTCFFNAVMQNLAQTYTLTDLMNEIKESSTKLKIFPSSDSQLDP
Sbjct: 181 GGKCRNLSVRGITNLGNTCFFNAVMQNLAQTYTLTDLMNEIKESSTKLKIFPSSDSQLDP 240
Query: 241 LVVELSRPGPLTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQQQDSQELLHY 300
LVVELSRPGPLTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQQQDSQELLHY
Sbjct: 241 LVVELSRPGPLTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQQQDSQELLHY 300
Query: 301 LLDAVRTEETKRIQASILKAFNNPTTKTADDETRKKVKAYGKEGVKMNFIDRIFIGELTS 360
LLDAVRTEETKRIQASILKAFNNPTTKTADDETRKKVKAYGKEGVKMNFIDRIFIGELTS
Sbjct: 301 LLDAVRTEETKRIQASILKAFNNPTTKTADDETRKKVKAYGKEGVKMNFIDRIFIGELTS 360
Query: 361 TVMCEECANISTVKDPFIDISLPIIEERVSKPLLWGRMNKYRSLRETDHDRYSGNVTIEN 420
TVMCEECANISTVKDPFIDISLPIIEERVSKPLLWGRMNKYRSLRETDHDRYSGNVTIEN
Sbjct: 361 TVMCEECANISTVKDPFIDISLPIIEERVSKPLLWGRMNKYRSLRETDHDRYSGNVTIEN 420
Query: 421 IHQPRAAKKHSSSKDKSQLIHDRKCIRKLSSGETVTYQKNENLEMNGDSLMFASLMNSES 480
IHQPRAAKKHSSSKDKSQLIHDRKCIRKLSSGETVTYQKNENLEMNGDSLMFASLMNSES
Sbjct: 421 IHQPRAAKKHSSSKDKSQLIHDRKCIRKLSSGETVTYQKNENLEMNGDSLMFASLMNSES 480
Query: 481 RLNESPTDDSEKEASHSESNVDADSEPSESESASKQTGLFRSSSGSGVQPDGPLYPLSAG 540
RLNESPTDDSEKEASHSESNVDADSEPSESESASKQTGLFRSSSGSGVQPDGPLYPLSAG
Sbjct: 481 RLNESPTDDSEKEASHSESNVDADSEPSESESASKQTGLFRSSSGSGVQPDGPLYPLSAG 540
Query: 541 KLLYTKETDSGDKEMAEAISELRLSSTVTGDQDFDRENQPLNISNNLCFLEGKHLRSYSP 600
KLLYTKETDSGDKEMAEAISELRLSSTVTGDQDFDRENQPLNISNNLCFLEGKHLRSYSP
Sbjct: 541 KLLYTKETDSGDKEMAEAISELRLSSTVTGDQDFDRENQPLNISNNLCFLEGKHLRSYSP 600
Query: 601 QNAFQTLSQSYITTSKECSIQSCLYQFTSMELLMGNNKLLCENCTKNKQKYQEETSFAEK 660
QNAFQTLSQSYITTSKECSIQSCLYQFTSMELLMGNNKLLCENCTKNKQKYQEETSFAEK
Sbjct: 601 QNAFQTLSQSYITTSKECSIQSCLYQFTSMELLMGNNKLLCENCTKNKQKYQEETSFAEK 660
Query: 661 KVEGVYTNARKQLLISAVPAVLILHLKRFHQAGLSLRKVNRHVDFPLMLDLAPFCSATCK 720
KVEGVYTNARKQLLISAVPAVLILHLKRFHQAGLSLRKVNRHVDFPLMLDLAPFCSATCK
Sbjct: 661 KVEGVYTNARKQLLISAVPAVLILHLKRFHQAGLSLRKVNRHVDFPLMLDLAPFCSATCK 720
Query: 721 NASVGDKVLYGLYGIVEHSGSMREGHYTAYVKVRTPSRKLSEHNTKKKNVPGLKAADNES 780
NASVGDKVLYGLYGIVEHSGSMREGHYTAYVKVRTPSRKLSEHNTKKKNVPGLKAADNES
Sbjct: 721 NASVGDKVLYGLYGIVEHSGSMREGHYTAYVKVRTPSRKLSEHNTKKKNVPGLKAADNES 780
Query: 781 AGQWVHVSDTYLQVVPESRALSAQAYLLFYERVL 814
AGQWVHVSDTYLQVVPESRALSAQAYLLFYERVL
Sbjct: 781 AGQWVHVSDTYLQVVPESRALSAQAYLLFYERVL 814
>gi|50312664 ubiquitin specific protease 16 isoform b [Homo sapiens]
Length = 822
Score = 553 bits (1424), Expect = e-157
Identities = 318/834 (38%), Positives = 479/834 (57%), Gaps = 49/834 (5%)
Query: 15 KRSKRPTVPHDEDSSDDIAVGLTCQHVSHAISVNHVKRAIAENLWSVCSECLKERRFYDG 74
KR+K TVP D DSS+ + C+H+ + ++K+A+ W++C +C + + D
Sbjct: 4 KRTKGKTVPID-DSSETLEP--VCRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDK 60
Query: 75 QLVLTSD---IWLCLKCGFQGCGKNSESQHSLKHFKSSRTEPHCIIINLSTWIIWCYECD 131
T + +WLCLKCG QGCG+NS+ QH+LKH+ + R+EPHC++++L W +WCY CD
Sbjct: 61 AEEETEEKPSVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCD 120
Query: 132 EKLSTHCNKKVLAQIVDFLQKHASKT-------------QTSAFSRIMKLCEEKCETDEI 178
++ +C+ L Q+VD+++K AS T + + K +E+ + + +
Sbjct: 121 NEVQ-YCSSNQLGQVVDYVRKQASITTPKPEKDNGNIELENKKLEKESKNEQEREKKENM 179
Query: 179 QKGGKCRN----LSVRGITNLGNTCFFNAVMQNLAQTYTLTDLMNEIKESSTKLKIFPSS 234
K N ++V+G++NLGNTCFFNAVMQNL+QT L +L+ E+K S T +KI P
Sbjct: 180 AKENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPPD 239
Query: 235 DSQLDPLVVELSRPGPLTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQQQDS 294
+ +PL + L PGPLT A+ FL+ M+ET+KG ++PK LF+Q+C+KA RFK +QQQDS
Sbjct: 240 LALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQDS 299
Query: 295 QELLHYLLDAVRTEETKRIQASILKAFNNPTTKTADDETRKKVKAYGKEGVKMNFIDRIF 354
QELL YLLD +R EE +R+ ILKAF N T K D+E + KVK Y K+ +F+DRIF
Sbjct: 300 QELLRYLLDGMRAEEHQRVSKGILKAFGNSTEK-LDEELKNKVKDYEKKKSMPSFVDRIF 358
Query: 355 IGELTSTVMCEECANISTVKDPFIDISLPIIEERVSKPLLWGRMNKYRSLRETDHD---- 410
GELTS +MC++C +S V + F+D+SLP+++++ K + N +++ + D D
Sbjct: 359 GGELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSV-NDKNLKKTVEDEDQDSEEE 417
Query: 411 RYSGNVTIENIHQPRAAKKHSSSKDKSQLIHDRKCIRKLSSGETVTYQKNENLEM-NGDS 469
+ + + E P KH K K Q K R+ + N+ + + +
Sbjct: 418 KDNDSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQRRQQKIQGKVLHLNDICTIDHPED 477
Query: 470 LMFASLMNSESRLNESPTDDSEKEASHSE---SNVDADSEPSESESASKQTGLFRSSSGS 526
+ + M+ + +N S++ H E + D + + ES +
Sbjct: 478 SEYEAEMSLQGEVNIKSNHISQEGVMHKEYCVNQKDLNGQAKMIESVTDNQKSTEEVDMK 537
Query: 527 GVQPDGPLYPLSAGKL-----LYTKETDSGDKEMAEAISELRLSSTVTGDQDFDRENQPL 581
+ D L L++ Y E +G+ +++ L L++ + D+ N +
Sbjct: 538 NINMDNDLEVLTSSPTRNLNGAYLTEGSNGEVDISNGFKNLNLNAALHPDE----INIEI 593
Query: 582 NISNNLCFLEGKHLRSYSPQNAFQTLSQSYITTSKECSIQSCLYQFTSMELLMGNNKLLC 641
++ + + + P+ AF TL+ + + ECSIQ CLYQFT E L NKLLC
Sbjct: 594 LNDSHTPGTKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLLC 653
Query: 642 ENCTKNKQKYQEETSFAEKKVEGVYTNARKQLLISAVPAVLILHLKRFHQAGLSLRKVNR 701
E CT+ + + E+K VYTNA+KQ+LIS P VL LHLKRF QAG +LRKVN+
Sbjct: 654 EVCTRRQCNGPKANIKGERK--HVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVNK 711
Query: 702 HVDFPLMLDLAPFCSATCKN-ASVGDKVLYGLYGIVEHSGSMREGHYTAYVKVRTPSRKL 760
H+ FP +LDLAPFC+ CKN A +VLY LYG+VEHSG+MR GHYTAY K RT + L
Sbjct: 712 HIKFPEILDLAPFCTLKCKNVAEENTRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSHL 771
Query: 761 SEHNTKKKNVPGLKAADNESAGQWVHVSDTYLQVVPESRALSAQAYLLFYERVL 814
S + ++P + + ES GQW H+SDT++Q VP ++ L++QAYLLFYER+L
Sbjct: 772 S-NLVLHGDIP--QDFEMESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYERIL 822
>gi|5454156 ubiquitin specific protease 16 isoform a [Homo sapiens]
Length = 823
Score = 552 bits (1423), Expect = e-157
Identities = 318/835 (38%), Positives = 479/835 (57%), Gaps = 50/835 (5%)
Query: 15 KRSKRPTVPHDEDSSDDIAVGLTCQHVSHAISVNHVKRAIAENLWSVCSECLKERRFYDG 74
KR+K TVP D DSS+ + C+H+ + ++K+A+ W++C +C + + D
Sbjct: 4 KRTKGKTVPID-DSSETLEP--VCRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDK 60
Query: 75 QLVLTSD---IWLCLKCGFQGCGKNSESQHSLKHFKSSRTEPHCIIINLSTWIIWCYECD 131
T + +WLCLKCG QGCG+NS+ QH+LKH+ + R+EPHC++++L W +WCY CD
Sbjct: 61 AEEETEEKPSVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCD 120
Query: 132 EKLSTHCNKKVLAQIVDFLQKHASKT--------------QTSAFSRIMKLCEEKCETDE 177
++ +C+ L Q+VD+++K AS T + + K +E+ + +
Sbjct: 121 NEVQ-YCSSNQLGQVVDYVRKQASITTPKPAEKDNGNIELENKKLEKESKNEQEREKKEN 179
Query: 178 IQKGGKCRN----LSVRGITNLGNTCFFNAVMQNLAQTYTLTDLMNEIKESSTKLKIFPS 233
+ K N ++V+G++NLGNTCFFNAVMQNL+QT L +L+ E+K S T +KI P
Sbjct: 180 MAKENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPP 239
Query: 234 SDSQLDPLVVELSRPGPLTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQQQD 293
+ +PL + L PGPLT A+ FL+ M+ET+KG ++PK LF+Q+C+KA RFK +QQQD
Sbjct: 240 DLALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQD 299
Query: 294 SQELLHYLLDAVRTEETKRIQASILKAFNNPTTKTADDETRKKVKAYGKEGVKMNFIDRI 353
SQELL YLLD +R EE +R+ ILKAF N T K D+E + KVK Y K+ +F+DRI
Sbjct: 300 SQELLRYLLDGMRAEEHQRVSKGILKAFGNSTEK-LDEELKNKVKDYEKKKSMPSFVDRI 358
Query: 354 FIGELTSTVMCEECANISTVKDPFIDISLPIIEERVSKPLLWGRMNKYRSLRETDHD--- 410
F GELTS +MC++C +S V + F+D+SLP+++++ K + N +++ + D D
Sbjct: 359 FGGELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSV-NDKNLKKTVEDEDQDSEE 417
Query: 411 -RYSGNVTIENIHQPRAAKKHSSSKDKSQLIHDRKCIRKLSSGETVTYQKNENLEM-NGD 468
+ + + E P KH K K Q K R+ + N+ + + +
Sbjct: 418 EKDNDSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQRRQQKIQGKVLHLNDICTIDHPE 477
Query: 469 SLMFASLMNSESRLNESPTDDSEKEASHSE---SNVDADSEPSESESASKQTGLFRSSSG 525
+ + M+ + +N S++ H E + D + + ES +
Sbjct: 478 DSEYEAEMSLQGEVNIKSNHISQEGVMHKEYCVNQKDLNGQAKMIESVTDNQKSTEEVDM 537
Query: 526 SGVQPDGPLYPLSAGKL-----LYTKETDSGDKEMAEAISELRLSSTVTGDQDFDRENQP 580
+ D L L++ Y E +G+ +++ L L++ + D+ N
Sbjct: 538 KNINMDNDLEVLTSSPTRNLNGAYLTEGSNGEVDISNGFKNLNLNAALHPDE----INIE 593
Query: 581 LNISNNLCFLEGKHLRSYSPQNAFQTLSQSYITTSKECSIQSCLYQFTSMELLMGNNKLL 640
+ ++ + + + P+ AF TL+ + + ECSIQ CLYQFT E L NKLL
Sbjct: 594 ILNDSHTPGTKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLL 653
Query: 641 CENCTKNKQKYQEETSFAEKKVEGVYTNARKQLLISAVPAVLILHLKRFHQAGLSLRKVN 700
CE CT+ + + E+K VYTNA+KQ+LIS P VL LHLKRF QAG +LRKVN
Sbjct: 654 CEVCTRRQCNGPKANIKGERK--HVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVN 711
Query: 701 RHVDFPLMLDLAPFCSATCKN-ASVGDKVLYGLYGIVEHSGSMREGHYTAYVKVRTPSRK 759
+H+ FP +LDLAPFC+ CKN A +VLY LYG+VEHSG+MR GHYTAY K RT +
Sbjct: 712 KHIKFPEILDLAPFCTLKCKNVAEENTRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSH 771
Query: 760 LSEHNTKKKNVPGLKAADNESAGQWVHVSDTYLQVVPESRALSAQAYLLFYERVL 814
LS + ++P + + ES GQW H+SDT++Q VP ++ L++QAYLLFYER+L
Sbjct: 772 LS-NLVLHGDIP--QDFEMESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYERIL 823
>gi|75992941 ubiquitin specific protease 16 isoform a [Homo sapiens]
Length = 823
Score = 552 bits (1423), Expect = e-157
Identities = 318/835 (38%), Positives = 479/835 (57%), Gaps = 50/835 (5%)
Query: 15 KRSKRPTVPHDEDSSDDIAVGLTCQHVSHAISVNHVKRAIAENLWSVCSECLKERRFYDG 74
KR+K TVP D DSS+ + C+H+ + ++K+A+ W++C +C + + D
Sbjct: 4 KRTKGKTVPID-DSSETLEP--VCRHIRKGLEQGNLKKALVNVEWNICQDCKTDNKVKDK 60
Query: 75 QLVLTSD---IWLCLKCGFQGCGKNSESQHSLKHFKSSRTEPHCIIINLSTWIIWCYECD 131
T + +WLCLKCG QGCG+NS+ QH+LKH+ + R+EPHC++++L W +WCY CD
Sbjct: 61 AEEETEEKPSVWLCLKCGHQGCGRNSQEQHALKHYLTPRSEPHCLVLSLDNWSVWCYVCD 120
Query: 132 EKLSTHCNKKVLAQIVDFLQKHASKT--------------QTSAFSRIMKLCEEKCETDE 177
++ +C+ L Q+VD+++K AS T + + K +E+ + +
Sbjct: 121 NEVQ-YCSSNQLGQVVDYVRKQASITTPKPAEKDNGNIELENKKLEKESKNEQEREKKEN 179
Query: 178 IQKGGKCRN----LSVRGITNLGNTCFFNAVMQNLAQTYTLTDLMNEIKESSTKLKIFPS 233
+ K N ++V+G++NLGNTCFFNAVMQNL+QT L +L+ E+K S T +KI P
Sbjct: 180 MAKENPPMNSPCQITVKGLSNLGNTCFFNAVMQNLSQTPVLRELLKEVKMSGTIVKIEPP 239
Query: 234 SDSQLDPLVVELSRPGPLTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQQQD 293
+ +PL + L PGPLT A+ FL+ M+ET+KG ++PK LF+Q+C+KA RFK +QQQD
Sbjct: 240 DLALTEPLEINLEPPGPLTLAMSQFLNEMQETKKGVVTPKELFSQVCKKAVRFKGYQQQD 299
Query: 294 SQELLHYLLDAVRTEETKRIQASILKAFNNPTTKTADDETRKKVKAYGKEGVKMNFIDRI 353
SQELL YLLD +R EE +R+ ILKAF N T K D+E + KVK Y K+ +F+DRI
Sbjct: 300 SQELLRYLLDGMRAEEHQRVSKGILKAFGNSTEK-LDEELKNKVKDYEKKKSMPSFVDRI 358
Query: 354 FIGELTSTVMCEECANISTVKDPFIDISLPIIEERVSKPLLWGRMNKYRSLRETDHD--- 410
F GELTS +MC++C +S V + F+D+SLP+++++ K + N +++ + D D
Sbjct: 359 FGGELTSMIMCDQCRTVSLVHESFLDLSLPVLDDQSGKKSV-NDKNLKKTVEDEDQDSEE 417
Query: 411 -RYSGNVTIENIHQPRAAKKHSSSKDKSQLIHDRKCIRKLSSGETVTYQKNENLEM-NGD 468
+ + + E P KH K K Q K R+ + N+ + + +
Sbjct: 418 EKDNDSYIKERSDIPSGTSKHLQKKAKKQAKKQAKNQRRQQKIQGKVLHLNDICTIDHPE 477
Query: 469 SLMFASLMNSESRLNESPTDDSEKEASHSE---SNVDADSEPSESESASKQTGLFRSSSG 525
+ + M+ + +N S++ H E + D + + ES +
Sbjct: 478 DSEYEAEMSLQGEVNIKSNHISQEGVMHKEYCVNQKDLNGQAKMIESVTDNQKSTEEVDM 537
Query: 526 SGVQPDGPLYPLSAGKL-----LYTKETDSGDKEMAEAISELRLSSTVTGDQDFDRENQP 580
+ D L L++ Y E +G+ +++ L L++ + D+ N
Sbjct: 538 KNINMDNDLEVLTSSPTRNLNGAYLTEGSNGEVDISNGFKNLNLNAALHPDE----INIE 593
Query: 581 LNISNNLCFLEGKHLRSYSPQNAFQTLSQSYITTSKECSIQSCLYQFTSMELLMGNNKLL 640
+ ++ + + + P+ AF TL+ + + ECSIQ CLYQFT E L NKLL
Sbjct: 594 ILNDSHTPGTKVYEVVNEDPETAFCTLANREVFNTDECSIQHCLYQFTRNEKLRDANKLL 653
Query: 641 CENCTKNKQKYQEETSFAEKKVEGVYTNARKQLLISAVPAVLILHLKRFHQAGLSLRKVN 700
CE CT+ + + E+K VYTNA+KQ+LIS P VL LHLKRF QAG +LRKVN
Sbjct: 654 CEVCTRRQCNGPKANIKGERK--HVYTNAKKQMLISLAPPVLTLHLKRFQQAGFNLRKVN 711
Query: 701 RHVDFPLMLDLAPFCSATCKN-ASVGDKVLYGLYGIVEHSGSMREGHYTAYVKVRTPSRK 759
+H+ FP +LDLAPFC+ CKN A +VLY LYG+VEHSG+MR GHYTAY K RT +
Sbjct: 712 KHIKFPEILDLAPFCTLKCKNVAEENTRVLYSLYGVVEHSGTMRSGHYTAYAKARTANSH 771
Query: 760 LSEHNTKKKNVPGLKAADNESAGQWVHVSDTYLQVVPESRALSAQAYLLFYERVL 814
LS + ++P + + ES GQW H+SDT++Q VP ++ L++QAYLLFYER+L
Sbjct: 772 LS-NLVLHGDIP--QDFEMESKGQWFHISDTHVQAVPTTKVLNSQAYLLFYERIL 823
>gi|42516561 ubiquitin specific protease 33 isoform 3 [Homo sapiens]
Length = 828
Score = 134 bits (337), Expect = 3e-31
Identities = 181/830 (21%), Positives = 303/830 (36%), Gaps = 162/830 (19%)
Query: 8 KALPEKAKRSKRPTVPHDEDSSDDIAVGLTCQHVSHAISVNHV-KRAIAENLWSVCSECL 66
K LP K+ +P+ + + H H SV + K + + C +C
Sbjct: 14 KVLPHFESLGKQEKIPNKMSAFRN--------HCPHLDSVGEITKEDLIQKSLGTCQDCK 65
Query: 67 KERRFYDGQLVLTSDIWLCL--KCGFQGCGKNSESQHSLKHFKSSRTEPHCIIINLSTWI 124
V ++W CL +C + GCG+ S+ HS H + ++ H + +NL+T
Sbjct: 66 ----------VQGPNLWACLENRCSYVGCGE-SQVDHSTIHSQETK---HYLTVNLTTLR 111
Query: 125 IWCYEC------DEKLSTHCNKKVLAQ--------IVDFLQKHASKTQTSAFSRIMKLCE 170
+WCY C D KL T + + Q + DF + +T + L
Sbjct: 112 VWCYACSKEVFLDRKLGTQPSLPHVRQPHQIQENSVQDFKIPSNTTLKTPLVAVFDDLDI 171
Query: 171 EKCETDEIQKGGKCRNLSVRGITNLGNTCFFNAVMQNLAQTYTLTDLMNEIKESSTKLKI 230
E E DE++ G + G+ N+GNTC+ NA +Q L+ LT + + K
Sbjct: 172 EADEEDELRARG------LTGLKNIGNTCYMNAALQALSNCPPLTQFFLDCGGLARTDK- 224
Query: 231 FPSSDSQLDPLVVELSRPGPLTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQ 290
+P S L L ++ G + P LF + P F+ +
Sbjct: 225 ----------------KPAICKSYLKLMTELWHKSRPGSVVPTTLFQGIKTVNPTFRGYS 268
Query: 291 QQDSQELLHYLLDAVRTEETKRIQASILKAFNNPTTKTADDETRKKVKAYGKEGVKMNFI 350
QQD+QE L L+D + E ++ +++ +P T T ++ + +
Sbjct: 269 QQDAQEFLRCLMDLLHEE----LKEQVMEVEEDPQTITTEETMEEDKSQSDVDFQSCESC 324
Query: 351 DRIFIGELTSTVMCEECANISTVKDPFIDISLPIIEERVSKPLLWGRMNKYRSLRETDHD 410
E + C N T D + + + K + ++NK S E D D
Sbjct: 325 SNSDRAENENGSRCFSEDNNETTMLIQDDENNSEMSKDWQKEKMCNKINKVNSEGEFDKD 384
Query: 411 RYSGNVTIE-NIHQPRAAKKHSSSKDKSQLIHDRKCIRKLSSGETVTYQKNENLEMNGDS 469
R S + T++ N + + HS + + +H LS+ + + + N
Sbjct: 385 RDSISETVDLNNQETVKVQIHSRASEYITDVHS----NDLSTPQILPSNEGVN------- 433
Query: 470 LMFASLMNSESRLNESPTDDSEKEASHSESNVDADSEPSESESASKQTGLFRSSSGSGVQ 529
RL+ SP + + A S S KQ +RS
Sbjct: 434 ----------PRLSASPPKSGNLWPGLAPPHKKAQ---SASPKRKKQHKKYRS------- 473
Query: 530 PDGPLYPLSAGKLLYTKETDSGDKEMAEAISELRLSSTVTGDQDFDR---ENQPLNISNN 586
+ + G ++ + + + D+ + LS + G +D + + P +I
Sbjct: 474 ---VISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPIPGKEDLAKLHSSSHPTSIVK- 529
Query: 587 LCFLEGKHLRSYSPQNAFQTLSQSYITT---SKECSIQSCLYQFTSMELLMGNNKLLCEN 643
G +Y+PQ + Y+ + ++Q CL F + + L G+N CE
Sbjct: 530 ----AGSCGEAYAPQ-GWIAFFMEYVKSWFWGPVVTLQDCLAAFFARDELKGDNMYSCEK 584
Query: 644 CTKNKQKYQEETSFAEKKVEGVYTNARKQLLISAVPAVLILHLKRFHQAGLSLRKVNRHV 703
C K + N K + P +L +HLKRF + K++ HV
Sbjct: 585 CKKLR-------------------NGVKFCKVQNFPEILCIHLKRFRHELMFSTKISTHV 625
Query: 704 DFPLM-LDLAPFCSATCKNASVGDKVLYGLYGIVEHSGSMREGHYTAYVKVRTPSRKLSE 762
FPL LDL PF + S V Y L ++ H G+ GHY AY +
Sbjct: 626 SFPLEGLDLQPFLA----KDSPAQIVTYDLLSVICHHGTASSGHYIAYCR---------- 671
Query: 763 HNTKKKNVPGLKAADNESAGQWVHVSDTYLQVVPESRALSAQAYLLFYER 812
N W D + V ES +A+AY+LFY +
Sbjct: 672 ---------------NNLNNLWYEFDDQSVTEVSESTVQNAEAYVLFYRK 706
>gi|42516567 ubiquitin specific protease 33 isoform 1 [Homo sapiens]
Length = 942
Score = 132 bits (332), Expect = 1e-30
Identities = 181/837 (21%), Positives = 304/837 (36%), Gaps = 168/837 (20%)
Query: 8 KALPEKAKRSKRPTVPHDEDSSDDIAVGLTCQHVSHAISVNHV-KRAIAENLWSVCSECL 66
K LP K+ +P+ + + H H SV + K + + C +C
Sbjct: 14 KVLPHFESLGKQEKIPNKMSAFRN--------HCPHLDSVGEITKEDLIQKSLGTCQDCK 65
Query: 67 KERRFYDGQLVLTSDIWLCL--KCGFQGCGKNSESQHSLKHFKSSRTEPHCIIINLSTWI 124
V ++W CL +C + GCG+ S+ HS H + ++ H + +NL+T
Sbjct: 66 ----------VQGPNLWACLENRCSYVGCGE-SQVDHSTIHSQETK---HYLTVNLTTLR 111
Query: 125 IWCYEC------DEKLSTHCNKKVLAQ--------IVDFLQKHASKTQTSAFSRIMKLCE 170
+WCY C D KL T + + Q + DF + +T + L
Sbjct: 112 VWCYACSKEVFLDRKLGTQPSLPHVRQPHQIQENSVQDFKIPSNTTLKTPLVAVFDDLDI 171
Query: 171 EKCETDEIQKGGKCRNLSVRGITNLGNTCFFNAVMQNLAQTYTLTDLMNEIKESSTKLKI 230
E E DE++ G + G+ N+GNTC+ NA +Q L+ LT + + K
Sbjct: 172 EADEEDELRARG------LTGLKNIGNTCYMNAALQALSNCPPLTQFFLDCGGLARTDK- 224
Query: 231 FPSSDSQLDPLVVELSRPGPLTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQ 290
+P S L L ++ G + P LF + P F+ +
Sbjct: 225 ----------------KPAICKSYLKLMTELWHKSRPGSVVPTTLFQGIKTVNPTFRGYS 268
Query: 291 QQDSQELLHYLLDAVRTEETKRIQASILKAFNNPTTKTADDETRKKVKAYGKEGVKMNFI 350
QQD+QE L L+D + E ++ +++ +P T T ++ + +
Sbjct: 269 QQDAQEFLRCLMDLLHEE----LKEQVMEVEEDPQTITTEETMEEDKSQSDVDFQSCESC 324
Query: 351 DRIFIGELTSTVMCEECANISTVKDPFIDISLPIIEERVSKPLLWGRMNKYRSLRETDHD 410
E + C N T D + + + K + ++NK S E D D
Sbjct: 325 SNSDRAENENGSRCFSEDNNETTMLIQDDENNSEMSKDWQKEKMCNKINKVNSEGEFDKD 384
Query: 411 RYSGNVTIE-NIHQPRAAKKHSSSKDKSQLIHDRKCIRKLSSGETVTYQKNENLEMNGDS 469
R S + T++ N + + HS + + +H LS+ + + + N
Sbjct: 385 RDSISETVDLNNQETVKVQIHSRASEYITDVHS----NDLSTPQILPSNEGVN------- 433
Query: 470 LMFASLMNSESRLNESPTDDSEKEASHSESNVDADSEPSESESASKQTGLFRSSSGSGVQ 529
RL+ SP + + A S S KQ +RS
Sbjct: 434 ----------PRLSASPPKSGNLWPGLAPPHKKAQ---SASPKRKKQHKKYRS------- 473
Query: 530 PDGPLYPLSAGKLLYTKETDSGDKEMAEAISELRLSSTVTGDQDFDR---ENQPLNISNN 586
+ + G ++ + + + D+ + LS + G +D + + P +I
Sbjct: 474 ---VISDIFDGTIISSVQCLTCDRVSVTLETFQDLSLPIPGKEDLAKLHSSSHPTSIVK- 529
Query: 587 LCFLEGKHLRSYSPQN---AFQTLSQSYITT-------SKECSIQSCLYQFTSMELLMGN 636
G +Y+PQ F + ++ + ++Q CL F + + L G+
Sbjct: 530 ----AGSCGEAYAPQGWIAFFMEYVKRFVVSCVPSWFWGPVVTLQDCLAAFFARDELKGD 585
Query: 637 NKLLCENCTKNKQKYQEETSFAEKKVEGVYTNARKQLLISAVPAVLILHLKRFHQAGLSL 696
N CE C K + N K + P +L +HLKRF +
Sbjct: 586 NMYSCEKCKKLR-------------------NGVKFCKVQNFPEILCIHLKRFRHELMFS 626
Query: 697 RKVNRHVDFPLM-LDLAPFCSATCKNASVGDKVLYGLYGIVEHSGSMREGHYTAYVKVRT 755
K++ HV FPL LDL PF + S V Y L ++ H G+ GHY AY +
Sbjct: 627 TKISTHVSFPLEGLDLQPFLA----KDSPAQIVTYDLLSVICHHGTASSGHYIAYCR--- 679
Query: 756 PSRKLSEHNTKKKNVPGLKAADNESAGQWVHVSDTYLQVVPESRALSAQAYLLFYER 812
N W D + V ES +A+AY+LFY +
Sbjct: 680 ----------------------NNLNNLWYEFDDQSVTEVSESTVQNAEAYVLFYRK 714
>gi|42516565 ubiquitin specific protease 33 isoform 2 [Homo sapiens]
Length = 911
Score = 132 bits (331), Expect = 2e-30
Identities = 176/805 (21%), Positives = 294/805 (36%), Gaps = 160/805 (19%)
Query: 40 HVSHAISVNHV-KRAIAENLWSVCSECLKERRFYDGQLVLTSDIWLCL--KCGFQGCGKN 96
H H SV + K + + C +C V ++W CL +C + GCG+
Sbjct: 7 HCPHLDSVGEITKEDLIQKSLGTCQDCK----------VQGPNLWACLENRCSYVGCGE- 55
Query: 97 SESQHSLKHFKSSRTEPHCIIINLSTWIIWCYEC------DEKLSTHCNKKVLAQ----- 145
S+ HS H + ++ H + +NL+T +WCY C D KL T + + Q
Sbjct: 56 SQVDHSTIHSQETK---HYLTVNLTTLRVWCYACSKEVFLDRKLGTQPSLPHVRQPHQIQ 112
Query: 146 ---IVDFLQKHASKTQTSAFSRIMKLCEEKCETDEIQKGGKCRNLSVRGITNLGNTCFFN 202
+ DF + +T + L E E DE++ G + G+ N+GNTC+ N
Sbjct: 113 ENSVQDFKIPSNTTLKTPLVAVFDDLDIEADEEDELRARG------LTGLKNIGNTCYMN 166
Query: 203 AVMQNLAQTYTLTDLMNEIKESSTKLKIFPSSDSQLDPLVVELSRPGPLTSALFLFLHSM 262
A +Q L+ LT + + K +P S L L
Sbjct: 167 AALQALSNCPPLTQFFLDCGGLARTDK-----------------KPAICKSYLKLMTELW 209
Query: 263 KETEKGPLSPKVLFNQLCQKAPRFKDFQQQDSQELLHYLLDAVRTEETKRIQASILKAFN 322
++ G + P LF + P F+ + QQD+QE L L+D + E ++ +++
Sbjct: 210 HKSRPGSVVPTTLFQGIKTVNPTFRGYSQQDAQEFLRCLMDLLHEE----LKEQVMEVEE 265
Query: 323 NPTTKTADDETRKKVKAYGKEGVKMNFIDRIFIGELTSTVMCEECANISTVKDPFIDISL 382
+P T T ++ + + E + C N T D +
Sbjct: 266 DPQTITTEETMEEDKSQSDVDFQSCESCSNSDRAENENGSRCFSEDNNETTMLIQDDENN 325
Query: 383 PIIEERVSKPLLWGRMNKYRSLRETDHDRYSGNVTIE-NIHQPRAAKKHSSSKDKSQLIH 441
+ + K + ++NK S E D DR S + T++ N + + HS + + +H
Sbjct: 326 SEMSKDWQKEKMCNKINKVNSEGEFDKDRDSISETVDLNNQETVKVQIHSRASEYITDVH 385
Query: 442 DRKCIRKLSSGETVTYQKNENLEMNGDSLMFASLMNSESRLNESPTDDSEKEASHSESNV 501
LS+ + + + N RL+ SP + +
Sbjct: 386 S----NDLSTPQILPSNEGVN-----------------PRLSASPPKSGNLWPGLAPPHK 424
Query: 502 DADSEPSESESASKQTGLFRSSSGSGVQPDGPLYPLSAGKLLYTKETDSGDKEMAEAISE 561
A S S KQ +RS + + G ++ + + + D+ +
Sbjct: 425 KAQ---SASPKRKKQHKKYRS----------VISDIFDGTIISSVQCLTCDRVSVTLETF 471
Query: 562 LRLSSTVTGDQDFDR---ENQPLNISNNLCFLEGKHLRSYSPQN---AFQTLSQSYITT- 614
LS + G +D + + P +I G +Y+PQ F + ++ +
Sbjct: 472 QDLSLPIPGKEDLAKLHSSSHPTSIVK-----AGSCGEAYAPQGWIAFFMEYVKRFVVSC 526
Query: 615 ------SKECSIQSCLYQFTSMELLMGNNKLLCENCTKNKQKYQEETSFAEKKVEGVYTN 668
++Q CL F + + L G+N CE C K + N
Sbjct: 527 VPSWFWGPVVTLQDCLAAFFARDELKGDNMYSCEKCKKLR-------------------N 567
Query: 669 ARKQLLISAVPAVLILHLKRFHQAGLSLRKVNRHVDFPLM-LDLAPFCSATCKNASVGDK 727
K + P +L +HLKRF + K++ HV FPL LDL PF + S
Sbjct: 568 GVKFCKVQNFPEILCIHLKRFRHELMFSTKISTHVSFPLEGLDLQPFLA----KDSPAQI 623
Query: 728 VLYGLYGIVEHSGSMREGHYTAYVKVRTPSRKLSEHNTKKKNVPGLKAADNESAGQWVHV 787
V Y L ++ H G+ GHY AY + N W
Sbjct: 624 VTYDLLSVICHHGTASSGHYIAYCR-------------------------NNLNNLWYEF 658
Query: 788 SDTYLQVVPESRALSAQAYLLFYER 812
D + V ES +A+AY+LFY +
Sbjct: 659 DDQSVTEVSESTVQNAEAYVLFYRK 683
>gi|40795665 ubiquitin specific protease 4 isoform a [Homo sapiens]
Length = 963
Score = 127 bits (319), Expect = 4e-29
Identities = 161/703 (22%), Positives = 274/703 (38%), Gaps = 164/703 (23%)
Query: 191 GITNLGNTCFFNAVMQNLAQTYTLTDLMNEIKESSTKLKIFPSSDSQLDPLVVELSRPGP 250
G+ NLGNTCF N+ +Q L+ T LTD +K+ + + ++ +PL ++ G
Sbjct: 303 GLGNLGNTCFMNSALQCLSNTAPLTDYF--LKDE------YEAEINRDNPLGMK----GE 350
Query: 251 LTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQQQDSQELLHYLLDAVRTEET 310
+ A + M ++P++ Q+ + AP+F +QQQDSQELL +LLD + E+
Sbjct: 351 IAEAYAELIKQMWSGRDAHVAPRMFKTQVGRFAPQFSGYQQQDSQELLAFLLDGLH-EDL 409
Query: 311 KRIQAS---ILKAFNNPTTKTADDETRKKVKAYGKEGVKMNFIDRIFIGELTSTVMCEEC 367
R++ LK N E + + + I F G ST++C EC
Sbjct: 410 NRVKKKPYLELKDANGRPDAVVAKEAWENHRLRND-----SVIVDTFHGLFKSTLVCPEC 464
Query: 368 ANISTVKDPFIDISLPI---------------------IEERVSKPLLWGRMNKYRSLRE 406
A +S DPF ++LP+ + RV+ PL+ + +L
Sbjct: 465 AKVSVTFDPFCYLTLPLPLKKDRVMEVFLVPADPHCRPTQYRVTVPLMGAVSDLCEAL-- 522
Query: 407 TDHDRYSG----NVTIENIHQPRAAK--------KH-------------SSSKDKSQLI- 440
R SG N+ + +++ R K H S+S D S+ +
Sbjct: 523 ---SRLSGIAAENMVVADVYNHRFHKIFQMDEGLNHIMPRDDIFVYEVCSTSVDGSECVT 579
Query: 441 -----HDRKCIRKLSSGETVTYQKNENLEMNGDSLMFASLMNSE----SRLNESPTDDS- 490
+RK +S + Y + L + L SL + SR + P D
Sbjct: 580 LPVYFRERKSRPSSTSSASALYGQPLLLSVPKHKLTLESLYQAVCDRISRYVKQPLPDEF 639
Query: 491 -----EKEASHSESNVDADSEPSESESASKQTGLFRSSSGSGVQPDG-----------PL 534
E A + N + E E + + GSG G
Sbjct: 640 GSSPLEPGACNGSRNSCEGEDEEEMEHQEEGKEQLSETEGSGEDEPGNDPSETTQKKIKG 699
Query: 535 YPLSAGKLLYTKETDSGDKEMAEAISE---LRLSSTVTGDQDFDRENQPLNISNNLCFLE 591
P ++ G ++ ++ L+L+S T D+D E + L
Sbjct: 700 QPCPKRLFTFSLVNSYGTADINSLAADGKLLKLNSRSTLAMDWDSETRRLYYDEQESEAY 759
Query: 592 GKHLRSYSPQNAFQTLSQSYITTSKECSIQSCLYQFTSMELLMGNNKLLCENCTKNKQKY 651
KH+ PQ +T +++ C+ FT+ME L ++ C NC K++Q
Sbjct: 760 EKHVSMLQPQKKKKT----------TVALRDCIELFTTMETLGEHDPWYCPNCKKHQQ-- 807
Query: 652 QEETSFAEKKVEGVYTNARKQLLISAVPAVLILHLKRFHQAGLSLRKVNRHVDFPLM-LD 710
A K+ + ++P +L++HLKRF K++ V+FP+ L+
Sbjct: 808 -----------------ATKKFDLWSLPKILVVHLKRFSYNRYWRDKLDTVVEFPIRGLN 850
Query: 711 LAPF-CSATCKNASVGDKVLYGLYGIVEHSGSMREGHYTAYVKVRTPSRKLSEHNTKKKN 769
++ F C+ + + +Y L + H G+M GHYTAY K
Sbjct: 851 MSEFVCNLSAR------PYVYDLIAVSNHYGAMGVGHYTAYAK----------------- 887
Query: 770 VPGLKAADNESAGQWVHVSDTYLQVVPESRALSAQAYLLFYER 812
N+ G+W + D+ + + E + ++ AY+LFY+R
Sbjct: 888 --------NKLNGKWYYFDDSNVSLASEDQIVTKAAYVLFYQR 922
>gi|40795667 ubiquitin specific protease 4 isoform b [Homo sapiens]
Length = 916
Score = 127 bits (319), Expect = 4e-29
Identities = 161/703 (22%), Positives = 274/703 (38%), Gaps = 164/703 (23%)
Query: 191 GITNLGNTCFFNAVMQNLAQTYTLTDLMNEIKESSTKLKIFPSSDSQLDPLVVELSRPGP 250
G+ NLGNTCF N+ +Q L+ T LTD +K+ + + ++ +PL ++ G
Sbjct: 256 GLGNLGNTCFMNSALQCLSNTAPLTDYF--LKDE------YEAEINRDNPLGMK----GE 303
Query: 251 LTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQQQDSQELLHYLLDAVRTEET 310
+ A + M ++P++ Q+ + AP+F +QQQDSQELL +LLD + E+
Sbjct: 304 IAEAYAELIKQMWSGRDAHVAPRMFKTQVGRFAPQFSGYQQQDSQELLAFLLDGLH-EDL 362
Query: 311 KRIQAS---ILKAFNNPTTKTADDETRKKVKAYGKEGVKMNFIDRIFIGELTSTVMCEEC 367
R++ LK N E + + + I F G ST++C EC
Sbjct: 363 NRVKKKPYLELKDANGRPDAVVAKEAWENHRLRND-----SVIVDTFHGLFKSTLVCPEC 417
Query: 368 ANISTVKDPFIDISLPI---------------------IEERVSKPLLWGRMNKYRSLRE 406
A +S DPF ++LP+ + RV+ PL+ + +L
Sbjct: 418 AKVSVTFDPFCYLTLPLPLKKDRVMEVFLVPADPHCRPTQYRVTVPLMGAVSDLCEAL-- 475
Query: 407 TDHDRYSG----NVTIENIHQPRAAK--------KH-------------SSSKDKSQLI- 440
R SG N+ + +++ R K H S+S D S+ +
Sbjct: 476 ---SRLSGIAAENMVVADVYNHRFHKIFQMDEGLNHIMPRDDIFVYEVCSTSVDGSECVT 532
Query: 441 -----HDRKCIRKLSSGETVTYQKNENLEMNGDSLMFASLMNSE----SRLNESPTDDS- 490
+RK +S + Y + L + L SL + SR + P D
Sbjct: 533 LPVYFRERKSRPSSTSSASALYGQPLLLSVPKHKLTLESLYQAVCDRISRYVKQPLPDEF 592
Query: 491 -----EKEASHSESNVDADSEPSESESASKQTGLFRSSSGSGVQPDG-----------PL 534
E A + N + E E + + GSG G
Sbjct: 593 GSSPLEPGACNGSRNSCEGEDEEEMEHQEEGKEQLSETEGSGEDEPGNDPSETTQKKIKG 652
Query: 535 YPLSAGKLLYTKETDSGDKEMAEAISE---LRLSSTVTGDQDFDRENQPLNISNNLCFLE 591
P ++ G ++ ++ L+L+S T D+D E + L
Sbjct: 653 QPCPKRLFTFSLVNSYGTADINSLAADGKLLKLNSRSTLAMDWDSETRRLYYDEQESEAY 712
Query: 592 GKHLRSYSPQNAFQTLSQSYITTSKECSIQSCLYQFTSMELLMGNNKLLCENCTKNKQKY 651
KH+ PQ +T +++ C+ FT+ME L ++ C NC K++Q
Sbjct: 713 EKHVSMLQPQKKKKT----------TVALRDCIELFTTMETLGEHDPWYCPNCKKHQQ-- 760
Query: 652 QEETSFAEKKVEGVYTNARKQLLISAVPAVLILHLKRFHQAGLSLRKVNRHVDFPLM-LD 710
A K+ + ++P +L++HLKRF K++ V+FP+ L+
Sbjct: 761 -----------------ATKKFDLWSLPKILVVHLKRFSYNRYWRDKLDTVVEFPIRGLN 803
Query: 711 LAPF-CSATCKNASVGDKVLYGLYGIVEHSGSMREGHYTAYVKVRTPSRKLSEHNTKKKN 769
++ F C+ + + +Y L + H G+M GHYTAY K
Sbjct: 804 MSEFVCNLSAR------PYVYDLIAVSNHYGAMGVGHYTAYAK----------------- 840
Query: 770 VPGLKAADNESAGQWVHVSDTYLQVVPESRALSAQAYLLFYER 812
N+ G+W + D+ + + E + ++ AY+LFY+R
Sbjct: 841 --------NKLNGKWYYFDDSNVSLASEDQIVTKAAYVLFYQR 875
>gi|55770886 ubiquitin thiolesterase 3 [Homo sapiens]
Length = 520
Score = 94.0 bits (232), Expect = 5e-19
Identities = 81/330 (24%), Positives = 140/330 (42%), Gaps = 38/330 (11%)
Query: 83 WLCLKCGFQGCGKNSESQHSLKHFKSSRTE-------------PHCIIINLSTWIIWCYE 129
W+CL C CG+ H+ KH++ ++ H + ++ S++ +CY
Sbjct: 39 WVCLTCSSVHCGRYVNG-HAKKHYEDAQVPLTNHKKSEKQDKVQHTVCMDCSSYSTYCYR 97
Query: 130 CDEKLSTHCNKKVLAQIVDFLQKHASKTQTSAFSRIMKLCEEKCETDEIQK-GGKCRNLS 188
CD+ + ++ ++ + LQ + T+ + KL E ++ K G +
Sbjct: 98 CDDFVVNDTKLGLVQKVREHLQNLENSAFTADRHKKRKLLENSTLNSKLLKVNGSTTAIC 157
Query: 189 VRGITNLGNTCFFNAVMQNLAQTYTLTDLMNEI-----KESSTKLKIFPSSDSQLDPLVV 243
G+ NLGNTCF NA++Q+L+ E+ + T + + SQ D V
Sbjct: 158 ATGLRNLGNTCFMNAILQSLSNIEQFCCYFKELPAVELRNGKTAGRRTYHTRSQGDNNV- 216
Query: 244 ELSRPGPLTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQQQDSQELLHYLLD 303
L L ++ + + SP+ LF + + P F+ +QQQD+ E + YLLD
Sbjct: 217 ------SLVEEFRKTLCALWQGSQTAFSPESLFYVVWKIMPNFRGYQQQDAHEFMRYLLD 270
Query: 304 AVRTEETKRIQASILKAFNNPTTKTADDETRKKVKAYGKEGVK--MNFIDRIFIGELTST 361
+ E L+ N +++A + + A K + + IF G L +
Sbjct: 271 HLHLE---------LQGGFNGVSRSAILQENSTLSASNKCCINGASTVVTAIFGGILQNE 321
Query: 362 VMCEECANISTVKDPFIDISLPIIEERVSK 391
V C C S DPF+D+SL I + SK
Sbjct: 322 VNCLICGTESRKFDPFLDLSLDIPSQFRSK 351
Score = 80.5 bits (197), Expect = 6e-15
Identities = 67/233 (28%), Positives = 95/233 (40%), Gaps = 58/233 (24%)
Query: 588 CFLEGKHLRSYSP--------QNAFQTLSQSYITTSKECSIQSCLYQFTSMELLMGNNKL 639
C + G R + P + F++ CS++ CL FT +E L
Sbjct: 324 CLICGTESRKFDPFLDLSLDIPSQFRSKRSKNQENGPVCSLRDCLRSFTDLEELDETELY 383
Query: 640 LCENCTKNKQKYQEETSFAEKKVEGVYTNARKQLLISAVPAVLILHLKRFHQAGLSLRKV 699
+C C K KQK + K+ I +P VL LHLKRFH KV
Sbjct: 384 MCHKC-KKKQK------------------STKKFWIQKLPKVLCLHLKRFHWTAYLRNKV 424
Query: 700 NRHVDFPLM-LDLAPFCSATCKNASVGDKVLYGLYGIVEHSGS-MREGHYTAYVKVRTPS 757
+ +V+FPL LD+ C S + LY L +V H GS + GHYTAY
Sbjct: 425 DTYVEFPLRGLDMK--CYLLEPENSGPESCLYDLAAVVVHHGSGVGSGHYTAY------- 475
Query: 758 RKLSEHNTKKKNVPGLKAADNESAGQWVHVSDTYLQVVPESRALSAQAYLLFY 810
A +E G+W H +D+ + + E + A+AY+LFY
Sbjct: 476 ------------------ATHE--GRWFHFNDSTVTLTDEETVVKAKAYILFY 508
>gi|109134334 ubiquitin thiolesterase 44 [Homo sapiens]
Length = 712
Score = 88.6 bits (218), Expect = 2e-17
Identities = 63/198 (31%), Positives = 90/198 (45%), Gaps = 36/198 (18%)
Query: 615 SKECSIQSCLYQFTSMELLMGNNKLLCENCTKNKQKYQEETSFAEKKVEGVYTNARKQLL 674
S+ C + L +FT E L G +C+ C +++ F+ K V V T A+KQL+
Sbjct: 512 SQPCLVTEMLAKFTETEALEGKI-YVCDQCNSKRRR------FSSKPV--VLTEAQKQLM 562
Query: 675 ISAVPAVLILHLKRFHQAGLSLR-KVNRHVDFPLMLDLAPFCSATCKNASVGDKVLYGLY 733
I +P VL LHLKRF +G + R K+ HV F +L++ P+C + + +Y L
Sbjct: 563 ICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFEEILNMEPYCCRETLKSLRPECFIYDLS 622
Query: 734 GIVEHSG-SMREGHYTAYVKVRTPSRKLSEHNTKKKNVPGLKAADNESAGQWVHVSDTYL 792
+V H G GHYTAY N G WVH +D+ L
Sbjct: 623 AVVMHHGKGFGSGHYTAY-------------------------CYNSEGGFWVHCNDSKL 657
Query: 793 QVVPESRALSAQAYLLFY 810
+ AQAY+LFY
Sbjct: 658 SMCTMDEVCKAQAYILFY 675
Score = 60.1 bits (144), Expect = 8e-09
Identities = 64/247 (25%), Positives = 93/247 (37%), Gaps = 66/247 (26%)
Query: 189 VRGITNLGNTCFFNAVMQNLAQ---------------------------------TYTLT 215
V G+ NLGNTC+ N+V+Q L+ T T+
Sbjct: 272 VTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAMTASEKTRSCKHPPVTDTVV 331
Query: 216 DLMNEIKESSTKLKIFPSSDSQLDPLV---------VELSRPGPLTSALFLFLHS----- 261
MNE +E T S S L + +EL +P TS H
Sbjct: 332 YQMNECQEKDTGFVC--SRQSSLSSGLSGGASKGRKMELIQPKEPTSQYISLCHELHTLF 389
Query: 262 --MKETEKGPLSPKVLFNQLCQKAPRFKDFQQQDSQELLHYLLDAVRTEETKRIQASILK 319
M + +SP + + + + P F+ + QQD+QE L LLD ++ E L+
Sbjct: 390 QVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQRE---------LE 440
Query: 320 AFNNPTTKTADDETRKKVKAYGKEGVKMNFIDRIFIGELTSTVMCEECANISTVKDPFID 379
RK +K +N ++ IF G+L S V C C N S +PF D
Sbjct: 441 TTGTSLPALIPTSQRKLIKQV------LNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWD 494
Query: 380 ISLPIIE 386
+SL E
Sbjct: 495 LSLEFPE 501
Score = 48.1 bits (113), Expect = 3e-05
Identities = 28/93 (30%), Positives = 49/93 (52%), Gaps = 9/93 (9%)
Query: 79 TSDIWLCLKCGFQGCGKNSESQHSLKHFKSSRTEPHCIIINLSTWIIWCYECDEKL---S 135
T IW CL C CG+ E +H+LKHF+ S H + + ++ ++CY CD+ + +
Sbjct: 35 TESIWACLSCSHVACGRYIE-EHALKHFQES---SHPVALEVNEMYVFCYLCDDYVLNDN 90
Query: 136 THCNKKVLAQIVDFL--QKHASKTQTSAFSRIM 166
T + K+L + + + Q + T++ F R M
Sbjct: 91 TTGDLKLLRRTLSAIKSQNYHCTTRSGRFLRSM 123
>gi|109134332 ubiquitin thiolesterase 44 [Homo sapiens]
Length = 712
Score = 88.6 bits (218), Expect = 2e-17
Identities = 63/198 (31%), Positives = 90/198 (45%), Gaps = 36/198 (18%)
Query: 615 SKECSIQSCLYQFTSMELLMGNNKLLCENCTKNKQKYQEETSFAEKKVEGVYTNARKQLL 674
S+ C + L +FT E L G +C+ C +++ F+ K V V T A+KQL+
Sbjct: 512 SQPCLVTEMLAKFTETEALEGKI-YVCDQCNSKRRR------FSSKPV--VLTEAQKQLM 562
Query: 675 ISAVPAVLILHLKRFHQAGLSLR-KVNRHVDFPLMLDLAPFCSATCKNASVGDKVLYGLY 733
I +P VL LHLKRF +G + R K+ HV F +L++ P+C + + +Y L
Sbjct: 563 ICHLPQVLRLHLKRFRWSGRNNREKIGVHVGFEEILNMEPYCCRETLKSLRPECFIYDLS 622
Query: 734 GIVEHSG-SMREGHYTAYVKVRTPSRKLSEHNTKKKNVPGLKAADNESAGQWVHVSDTYL 792
+V H G GHYTAY N G WVH +D+ L
Sbjct: 623 AVVMHHGKGFGSGHYTAY-------------------------CYNSEGGFWVHCNDSKL 657
Query: 793 QVVPESRALSAQAYLLFY 810
+ AQAY+LFY
Sbjct: 658 SMCTMDEVCKAQAYILFY 675
Score = 60.1 bits (144), Expect = 8e-09
Identities = 64/247 (25%), Positives = 93/247 (37%), Gaps = 66/247 (26%)
Query: 189 VRGITNLGNTCFFNAVMQNLAQ---------------------------------TYTLT 215
V G+ NLGNTC+ N+V+Q L+ T T+
Sbjct: 272 VTGLRNLGNTCYMNSVLQVLSHLLIFRQCFLKLDLNQWLAMTASEKTRSCKHPPVTDTVV 331
Query: 216 DLMNEIKESSTKLKIFPSSDSQLDPLV---------VELSRPGPLTSALFLFLHS----- 261
MNE +E T S S L + +EL +P TS H
Sbjct: 332 YQMNECQEKDTGFVC--SRQSSLSSGLSGGASKGRKMELIQPKEPTSQYISLCHELHTLF 389
Query: 262 --MKETEKGPLSPKVLFNQLCQKAPRFKDFQQQDSQELLHYLLDAVRTEETKRIQASILK 319
M + +SP + + + + P F+ + QQD+QE L LLD ++ E L+
Sbjct: 390 QVMWSGKWALVSPFAMLHSVWRLIPAFRGYAQQDAQEFLCELLDKIQRE---------LE 440
Query: 320 AFNNPTTKTADDETRKKVKAYGKEGVKMNFIDRIFIGELTSTVMCEECANISTVKDPFID 379
RK +K +N ++ IF G+L S V C C N S +PF D
Sbjct: 441 TTGTSLPALIPTSQRKLIKQV------LNVVNNIFHGQLLSQVTCLACDNKSNTIEPFWD 494
Query: 380 ISLPIIE 386
+SL E
Sbjct: 495 LSLEFPE 501
Score = 48.1 bits (113), Expect = 3e-05
Identities = 28/93 (30%), Positives = 49/93 (52%), Gaps = 9/93 (9%)
Query: 79 TSDIWLCLKCGFQGCGKNSESQHSLKHFKSSRTEPHCIIINLSTWIIWCYECDEKL---S 135
T IW CL C CG+ E +H+LKHF+ S H + + ++ ++CY CD+ + +
Sbjct: 35 TESIWACLSCSHVACGRYIE-EHALKHFQES---SHPVALEVNEMYVFCYLCDDYVLNDN 90
Query: 136 THCNKKVLAQIVDFL--QKHASKTQTSAFSRIM 166
T + K+L + + + Q + T++ F R M
Sbjct: 91 TTGDLKLLRRTLSAIKSQNYHCTTRSGRFLRSM 123
>gi|41152235 ubiquitin specific protease 51 [Homo sapiens]
Length = 711
Score = 87.8 bits (216), Expect = 4e-17
Identities = 89/316 (28%), Positives = 132/316 (41%), Gaps = 62/316 (19%)
Query: 85 CLKCGFQGCGKNSESQHSLKHFKSSRTEPHCIIINLSTWIIWCYECD--------EKLST 136
CL C F GC +H KH + T+ H + ++L +I+C+ C E+++
Sbjct: 249 CLSCVFFGC---FTEKHIHKH---AETKQHHLAVDLYHGVIYCFMCKDYVYDKDIEQIAK 302
Query: 137 HCNKKVLAQIVDFLQKHASKTQ--TSAFSRIMKLCEEKCETDEIQKGGKCRN------LS 188
+K+L +++ S Q TS F CE K + ++ K K R +
Sbjct: 303 ETKEKIL-RLLTSTSTDVSHQQFMTSGFEDKQSTCETKEQEPKLVKPKKKRRKKSVYTVG 361
Query: 189 VRGITNLGNTCFFNAVMQNLAQTYTLTDLMNEIKESSTKLKIFPSSDSQLDPLVVELSRP 248
+RG+ NLGNTCF N ++Q L L D S K K +S S LV E+S
Sbjct: 362 LRGLINLGNTCFMNCIVQALTHIPLLKDFF-----LSDKHKCIMTSPSLC--LVCEMS-- 412
Query: 249 GPLTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQQQDSQELLHYLLDAVRTE 308
+LF H+M + P P L + + A ++QQD+ E L +LD +
Sbjct: 413 -----SLF---HAMYSGSRTPHIPYKLLHLIWIHAEHLAGYRQQDAHEFLIAILDVLHRH 464
Query: 309 ETKRIQASILKAFNNPTTKTADDETRKKVKAYGKEGVKMNFIDRIFIGELTSTVMCEECA 368
S + NNP ID+IF G L S V C+ C
Sbjct: 465 SK---DDSGGQEANNPNCCNC-------------------IIDQIFTGGLQSDVTCQACH 502
Query: 369 NISTVKDPFIDISLPI 384
++ST DP DISL +
Sbjct: 503 SVSTTIDPCWDISLDL 518
Score = 85.1 bits (209), Expect = 2e-16
Identities = 60/225 (26%), Positives = 93/225 (41%), Gaps = 55/225 (24%)
Query: 597 SYSPQNAFQTLSQSYITTSKECSIQSCLYQFTSMELLMGNNKLLCENCTKNKQKYQEETS 656
S +P+ A T+S+ S+ CL FT E L + K+ C +C Q YQE T
Sbjct: 527 SQNPERADSTVSRDDHIPGIP-SLTDCLQWFTRPEHLGSSAKIKCNSC----QSYQEST- 580
Query: 657 FAEKKVEGVYTNARKQLLISAVPAVLILHLKRFHQAGLSLRKVNRHVDFPLMLDLAPFCS 716
KQL + +P V HLKRF G RK+N + FPL LD+ PF +
Sbjct: 581 --------------KQLTMKKLPIVACFHLKRFEHVGKQRRKINTFISFPLELDMTPFLA 626
Query: 717 ATCKNA---------SVGDKVLYGLYGIVEHSGSMREGHYTAYVKVRTPSRKLSEHNTKK 767
+T ++ V ++ Y L+ ++ H G++ GHYT++++
Sbjct: 627 STKESRMKEGQPPTDCVPNENKYSLFAVINHHGTLESGHYTSFIR--------------- 671
Query: 768 KNVPGLKAADNESAGQWVHVSDTYLQVVPESRALSAQAYLLFYER 812
+ QW D + L ++ YLLFY +
Sbjct: 672 -----------QQKDQWFSCDDAIITKATIEDLLYSEGYLLFYHK 705
>gi|63053524 ubiquitin specific protease 1 [Homo sapiens]
Length = 785
Score = 86.3 bits (212), Expect = 1e-16
Identities = 138/602 (22%), Positives = 235/602 (39%), Gaps = 122/602 (20%)
Query: 191 GITNLGNTCFFNAVMQNL------------------AQTYTLTDLMNEIKESSTKLKIFP 232
G+ NLGNTC+ N+++Q L + L D N+ + + K
Sbjct: 82 GLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKKEALKDEANQKDKGNCKEDSLA 141
Query: 233 SSD--SQLDPLVVELSRPGPLTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQ 290
S + L L++ + + A FL L+ K T++ P+ L N L + P ++ +
Sbjct: 142 SYELICSLQSLIISVEQ----LQASFL-LNPEKYTDELATQPRRLLNTLRELNPMYEGYL 196
Query: 291 QQDSQELLHYLLDAVRTEETKRIQASILKAFNNPTTKTADDETRKKVKAYGKEGVKMNFI 350
Q D+QE+L +L + +ET +LK A+ T+ + + KE +MN I
Sbjct: 197 QHDAQEVLQCILGNI--QET----CQLLK--KEEVKNVAELPTKVEEIPHPKE--EMNGI 246
Query: 351 DRIFIGELTSTVMCEECANISTVKDPFIDISLPIIEERVSKPLLWGRMNKYRSLRETDHD 410
+ I + + + +E LP + +G M K L + +H
Sbjct: 247 NSIEMDSMRHSEDFKE--------------KLPKGNGKRKSDTEFGNMKKKVKLSK-EHQ 291
Query: 411 RYSGNVTIENIHQPRAAKKHSSSKDKSQLIHDRKCIRKLSSGETVTYQKNENLEMNGDSL 470
EN Q R+ +K +S +S K I + S + + +
Sbjct: 292 SLE-----ENQRQTRSKRKATSDTLESPPKIIPKYISENESPRPSQKKSRVKINWLKSAT 346
Query: 471 MFASLMNSESRLNESPTDDSEKEASHSESNVDADSEPSESESASKQTGLFRSSSGSGVQP 530
S+++ L + T+ K S E+ D + + + ES + G S G+ V P
Sbjct: 347 KQPSILSKFCSLGKITTNQGVKGQS-KENECDPEEDLGKCESDNTTNGCGLESPGNTVTP 405
Query: 531 DG--PLYPLSAGKLLYTKETDSGDKEMAEAISE---------LRLSSTVTGDQDFDRENQ 579
+ P++ G+ + E+ E + + L S +DF +
Sbjct: 406 VNVNEVKPINKGE-------EQIGFELVEKLFQGQLVLRTRCLECESLTERREDFQDISV 458
Query: 580 PLNISNNLCFLEGKHLRSYSPQNAFQTLSQSYITTSKECSIQSCLYQFTSMELLMGNNKL 639
P+ + L +E S P+ +TL + + QF S+E ++G +K
Sbjct: 459 PVQ-EDELSKVEESSEISPEPKTEMKTLRWA-------------ISQFASVERIVGEDKY 504
Query: 640 LCENCTKNKQKYQEETSFAEKKVEGVYTNARKQLLISAVPAVLILHLKRFHQAGL----- 694
CENC YT A + LL +P V+ +HLK F +GL
Sbjct: 505 FCENCHH-------------------YTEAERSLLFDKMPEVITIHLKCFAASGLEFDCY 545
Query: 695 --SLRKVNRHVDFPLMLDLAPFCSATCKNASVGDKVLYGLYGIVEHSG-SMREGHYTAYV 751
L K+N + PL L L + + ++ YGL+ +V HSG ++ GHYTA V
Sbjct: 546 GGGLSKINTPLLTPLKLSLEEWSTKPTNDS-------YGLFAVVMHSGITISSGHYTASV 598
Query: 752 KV 753
KV
Sbjct: 599 KV 600
>gi|63053522 ubiquitin specific protease 1 [Homo sapiens]
Length = 785
Score = 86.3 bits (212), Expect = 1e-16
Identities = 138/602 (22%), Positives = 235/602 (39%), Gaps = 122/602 (20%)
Query: 191 GITNLGNTCFFNAVMQNL------------------AQTYTLTDLMNEIKESSTKLKIFP 232
G+ NLGNTC+ N+++Q L + L D N+ + + K
Sbjct: 82 GLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKKEALKDEANQKDKGNCKEDSLA 141
Query: 233 SSD--SQLDPLVVELSRPGPLTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQ 290
S + L L++ + + A FL L+ K T++ P+ L N L + P ++ +
Sbjct: 142 SYELICSLQSLIISVEQ----LQASFL-LNPEKYTDELATQPRRLLNTLRELNPMYEGYL 196
Query: 291 QQDSQELLHYLLDAVRTEETKRIQASILKAFNNPTTKTADDETRKKVKAYGKEGVKMNFI 350
Q D+QE+L +L + +ET +LK A+ T+ + + KE +MN I
Sbjct: 197 QHDAQEVLQCILGNI--QET----CQLLK--KEEVKNVAELPTKVEEIPHPKE--EMNGI 246
Query: 351 DRIFIGELTSTVMCEECANISTVKDPFIDISLPIIEERVSKPLLWGRMNKYRSLRETDHD 410
+ I + + + +E LP + +G M K L + +H
Sbjct: 247 NSIEMDSMRHSEDFKE--------------KLPKGNGKRKSDTEFGNMKKKVKLSK-EHQ 291
Query: 411 RYSGNVTIENIHQPRAAKKHSSSKDKSQLIHDRKCIRKLSSGETVTYQKNENLEMNGDSL 470
EN Q R+ +K +S +S K I + S + + +
Sbjct: 292 SLE-----ENQRQTRSKRKATSDTLESPPKIIPKYISENESPRPSQKKSRVKINWLKSAT 346
Query: 471 MFASLMNSESRLNESPTDDSEKEASHSESNVDADSEPSESESASKQTGLFRSSSGSGVQP 530
S+++ L + T+ K S E+ D + + + ES + G S G+ V P
Sbjct: 347 KQPSILSKFCSLGKITTNQGVKGQS-KENECDPEEDLGKCESDNTTNGCGLESPGNTVTP 405
Query: 531 DG--PLYPLSAGKLLYTKETDSGDKEMAEAISE---------LRLSSTVTGDQDFDRENQ 579
+ P++ G+ + E+ E + + L S +DF +
Sbjct: 406 VNVNEVKPINKGE-------EQIGFELVEKLFQGQLVLRTRCLECESLTERREDFQDISV 458
Query: 580 PLNISNNLCFLEGKHLRSYSPQNAFQTLSQSYITTSKECSIQSCLYQFTSMELLMGNNKL 639
P+ + L +E S P+ +TL + + QF S+E ++G +K
Sbjct: 459 PVQ-EDELSKVEESSEISPEPKTEMKTLRWA-------------ISQFASVERIVGEDKY 504
Query: 640 LCENCTKNKQKYQEETSFAEKKVEGVYTNARKQLLISAVPAVLILHLKRFHQAGL----- 694
CENC YT A + LL +P V+ +HLK F +GL
Sbjct: 505 FCENCHH-------------------YTEAERSLLFDKMPEVITIHLKCFAASGLEFDCY 545
Query: 695 --SLRKVNRHVDFPLMLDLAPFCSATCKNASVGDKVLYGLYGIVEHSG-SMREGHYTAYV 751
L K+N + PL L L + + ++ YGL+ +V HSG ++ GHYTA V
Sbjct: 546 GGGLSKINTPLLTPLKLSLEEWSTKPTNDS-------YGLFAVVMHSGITISSGHYTASV 598
Query: 752 KV 753
KV
Sbjct: 599 KV 600
>gi|31543910 ubiquitin specific protease 1 [Homo sapiens]
Length = 785
Score = 86.3 bits (212), Expect = 1e-16
Identities = 138/602 (22%), Positives = 235/602 (39%), Gaps = 122/602 (20%)
Query: 191 GITNLGNTCFFNAVMQNL------------------AQTYTLTDLMNEIKESSTKLKIFP 232
G+ NLGNTC+ N+++Q L + L D N+ + + K
Sbjct: 82 GLNNLGNTCYLNSILQVLYFCPGFKSGVKHLFNIISRKKEALKDEANQKDKGNCKEDSLA 141
Query: 233 SSD--SQLDPLVVELSRPGPLTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQ 290
S + L L++ + + A FL L+ K T++ P+ L N L + P ++ +
Sbjct: 142 SYELICSLQSLIISVEQ----LQASFL-LNPEKYTDELATQPRRLLNTLRELNPMYEGYL 196
Query: 291 QQDSQELLHYLLDAVRTEETKRIQASILKAFNNPTTKTADDETRKKVKAYGKEGVKMNFI 350
Q D+QE+L +L + +ET +LK A+ T+ + + KE +MN I
Sbjct: 197 QHDAQEVLQCILGNI--QET----CQLLK--KEEVKNVAELPTKVEEIPHPKE--EMNGI 246
Query: 351 DRIFIGELTSTVMCEECANISTVKDPFIDISLPIIEERVSKPLLWGRMNKYRSLRETDHD 410
+ I + + + +E LP + +G M K L + +H
Sbjct: 247 NSIEMDSMRHSEDFKE--------------KLPKGNGKRKSDTEFGNMKKKVKLSK-EHQ 291
Query: 411 RYSGNVTIENIHQPRAAKKHSSSKDKSQLIHDRKCIRKLSSGETVTYQKNENLEMNGDSL 470
EN Q R+ +K +S +S K I + S + + +
Sbjct: 292 SLE-----ENQRQTRSKRKATSDTLESPPKIIPKYISENESPRPSQKKSRVKINWLKSAT 346
Query: 471 MFASLMNSESRLNESPTDDSEKEASHSESNVDADSEPSESESASKQTGLFRSSSGSGVQP 530
S+++ L + T+ K S E+ D + + + ES + G S G+ V P
Sbjct: 347 KQPSILSKFCSLGKITTNQGVKGQS-KENECDPEEDLGKCESDNTTNGCGLESPGNTVTP 405
Query: 531 DG--PLYPLSAGKLLYTKETDSGDKEMAEAISE---------LRLSSTVTGDQDFDRENQ 579
+ P++ G+ + E+ E + + L S +DF +
Sbjct: 406 VNVNEVKPINKGE-------EQIGFELVEKLFQGQLVLRTRCLECESLTERREDFQDISV 458
Query: 580 PLNISNNLCFLEGKHLRSYSPQNAFQTLSQSYITTSKECSIQSCLYQFTSMELLMGNNKL 639
P+ + L +E S P+ +TL + + QF S+E ++G +K
Sbjct: 459 PVQ-EDELSKVEESSEISPEPKTEMKTLRWA-------------ISQFASVERIVGEDKY 504
Query: 640 LCENCTKNKQKYQEETSFAEKKVEGVYTNARKQLLISAVPAVLILHLKRFHQAGL----- 694
CENC YT A + LL +P V+ +HLK F +GL
Sbjct: 505 FCENCHH-------------------YTEAERSLLFDKMPEVITIHLKCFAASGLEFDCY 545
Query: 695 --SLRKVNRHVDFPLMLDLAPFCSATCKNASVGDKVLYGLYGIVEHSG-SMREGHYTAYV 751
L K+N + PL L L + + ++ YGL+ +V HSG ++ GHYTA V
Sbjct: 546 GGGLSKINTPLLTPLKLSLEEWSTKPTNDS-------YGLFAVVMHSGITISSGHYTASV 598
Query: 752 KV 753
KV
Sbjct: 599 KV 600
>gi|28565285 ubiquitin specific peptidase 2 isoform b [Homo sapiens]
Length = 396
Score = 81.6 bits (200), Expect = 3e-15
Identities = 61/198 (30%), Positives = 95/198 (47%), Gaps = 24/198 (12%)
Query: 191 GITNLGNTCFFNAVMQNLAQTYTLTDLMNEIKESSTKLKIFPSSDSQLDPLVVELSRPGP 250
G+ NLGNTCF N+++Q L+ T L D + ++ + LV E ++
Sbjct: 59 GLRNLGNTCFMNSILQCLSNTRELRDYCLQ----RLYMRDLHHGSNAHTALVEEFAK--- 111
Query: 251 LTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQQQDSQELLHYLLDAVRTEET 310
L + +SP Q+ + APRF + QQD+QE L +LLD + E
Sbjct: 112 ------LIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNE-- 163
Query: 311 KRIQASILKAFNNPTT--KTADDETRKKV--KAYGKEGVKMNFIDRIFIGELTSTVMCEE 366
+ L+ +NP DDE +++ K +E + I +F+G+L S++ C +
Sbjct: 164 --VNRVTLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSR---IGDLFVGQLKSSLTCTD 218
Query: 367 CANISTVKDPFIDISLPI 384
C STV DPF D+SLPI
Sbjct: 219 CGYCSTVFDPFWDLSLPI 236
Score = 77.4 bits (189), Expect = 5e-14
Identities = 54/196 (27%), Positives = 83/196 (42%), Gaps = 51/196 (26%)
Query: 617 ECSIQSCLYQFTSMELLMGNNKLLCENCTKNKQKYQEETSFAEKKVEGVYTNARKQLLIS 676
E ++ C+ FT ++L G+ K C C K+ K+ I
Sbjct: 243 EVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKR-------------------CIKKFSIQ 283
Query: 677 AVPAVLILHLKRFHQAGLSLRKVNRHVDFPLM-LDLAPFCSATCKNASVGDKVLYGLYGI 735
P +L+LHLKRF ++ + K+ V+FPL LDL F S +A +Y LY +
Sbjct: 284 RFPKILVLHLKRFSESRIRTSKLTTFVNFPLRDLDLREFASENTNHA------VYNLYAV 337
Query: 736 VEHSGSMREGHYTAYVKVRTPSRKLSEHNTKKKNVPGLKAADNESAGQWVHVSDTYLQVV 795
HSG+ GHYTAY + + G+W +D+ + +
Sbjct: 338 SNHSGTTMGGHYTAYCR-------------------------SPGTGEWHTFNDSSVTPM 372
Query: 796 PESRALSAQAYLLFYE 811
S+ ++ AYLLFYE
Sbjct: 373 SSSQVRTSDAYLLFYE 388
>gi|188528692 ubiquitin specific peptidase 2 isoform a [Homo
sapiens]
Length = 605
Score = 81.6 bits (200), Expect = 3e-15
Identities = 61/198 (30%), Positives = 95/198 (47%), Gaps = 24/198 (12%)
Query: 191 GITNLGNTCFFNAVMQNLAQTYTLTDLMNEIKESSTKLKIFPSSDSQLDPLVVELSRPGP 250
G+ NLGNTCF N+++Q L+ T L D + ++ + LV E ++
Sbjct: 268 GLRNLGNTCFMNSILQCLSNTRELRDYCLQ----RLYMRDLHHGSNAHTALVEEFAK--- 320
Query: 251 LTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQQQDSQELLHYLLDAVRTEET 310
L + +SP Q+ + APRF + QQD+QE L +LLD + E
Sbjct: 321 ------LIQTIWTSSPNDVVSPSEFKTQIQRYAPRFVGYNQQDAQEFLRFLLDGLHNE-- 372
Query: 311 KRIQASILKAFNNPTT--KTADDETRKKV--KAYGKEGVKMNFIDRIFIGELTSTVMCEE 366
+ L+ +NP DDE +++ K +E + I +F+G+L S++ C +
Sbjct: 373 --VNRVTLRPKSNPENLDHLPDDEKGRQMWRKYLEREDSR---IGDLFVGQLKSSLTCTD 427
Query: 367 CANISTVKDPFIDISLPI 384
C STV DPF D+SLPI
Sbjct: 428 CGYCSTVFDPFWDLSLPI 445
Score = 77.4 bits (189), Expect = 5e-14
Identities = 54/196 (27%), Positives = 83/196 (42%), Gaps = 51/196 (26%)
Query: 617 ECSIQSCLYQFTSMELLMGNNKLLCENCTKNKQKYQEETSFAEKKVEGVYTNARKQLLIS 676
E ++ C+ FT ++L G+ K C C K+ K+ I
Sbjct: 452 EVTLMDCMRLFTKEDVLDGDEKPTCCRCRGRKR-------------------CIKKFSIQ 492
Query: 677 AVPAVLILHLKRFHQAGLSLRKVNRHVDFPLM-LDLAPFCSATCKNASVGDKVLYGLYGI 735
P +L+LHLKRF ++ + K+ V+FPL LDL F S +A +Y LY +
Sbjct: 493 RFPKILVLHLKRFSESRIRTSKLTTFVNFPLRDLDLREFASENTNHA------VYNLYAV 546
Query: 736 VEHSGSMREGHYTAYVKVRTPSRKLSEHNTKKKNVPGLKAADNESAGQWVHVSDTYLQVV 795
HSG+ GHYTAY + + G+W +D+ + +
Sbjct: 547 SNHSGTTMGGHYTAYCR-------------------------SPGTGEWHTFNDSSVTPM 581
Query: 796 PESRALSAQAYLLFYE 811
S+ ++ AYLLFYE
Sbjct: 582 SSSQVRTSDAYLLFYE 597
>gi|57529246 ubiquitin thioesterase 19 [Homo sapiens]
Length = 1318
Score = 81.3 bits (199), Expect = 3e-15
Identities = 60/210 (28%), Positives = 102/210 (48%), Gaps = 25/210 (11%)
Query: 191 GITNLGNTCFFNAVMQNLAQTYTLTDLMNEIKESSTKLKIFPSSDSQLDPLVVELSRPGP 250
G+ NLGNTCF N+V+Q+L+ T L D ++ + F + + +P L G
Sbjct: 498 GLVNLGNTCFMNSVIQSLSNTRELRDFFHD--------RSFEAEINYNNP----LGTGGR 545
Query: 251 LTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQQQDSQELLHYLLDAVRTEET 310
L + L ++ + P L + KA +F + Q D+QE + +LLD + E+
Sbjct: 546 LAIGFAVLLRALWKGTHHAFQPSKLKAIVASKASQFTGYAQHDAQEFMAFLLDGLH-EDL 604
Query: 311 KRIQASILKAFNNPTTKTADDETR--KKVKAYGKEGVKM---NFIDRIFIGELTSTVMCE 365
RIQ N P T+T D + R + V + KM +FI +F G+ S ++C
Sbjct: 605 NRIQ-------NKPYTETVDSDGRPDEVVAEEAWQRHKMRNDSFIVDLFQGQYKSKLVCP 657
Query: 366 ECANISTVKDPFIDISLPIIEERVSKPLLW 395
CA +S DPF+ + +P+ +++ P+ +
Sbjct: 658 VCAKVSITFDPFLYLPVPLPQKQKVLPVFY 687
Score = 71.2 bits (173), Expect = 4e-12
Identities = 58/200 (29%), Positives = 86/200 (43%), Gaps = 51/200 (25%)
Query: 619 SIQSCLYQFTSMELLMGNNKLLCENCTKNKQKYQEETSFAEKKVEGVYTNARKQLLISAV 678
++ CL FT E+L C C ++++ A KQLL+ +
Sbjct: 1059 TLDQCLNLFTRPEVLAPEEAWYCPQCKQHRE-------------------ASKQLLLWRL 1099
Query: 679 PAVLILHLKRFHQAGLSLR-KVNRHVDFPLM-LDLAPFCSATCKNASVGDKV----LYGL 732
P VLI+ LKRF R K+N V+FP+ LDL+ FC +G K Y L
Sbjct: 1100 PNVLIVQLKRFSFRSFIWRDKINDLVEFPVRNLDLSKFC--------IGQKEEQLPSYDL 1151
Query: 733 YGIVEHSGSMREGHYTAYVKVRTPSRKLSEHNTKKKNVPGLKAADNESAGQWVHVSDTYL 792
Y ++ H G M GHYTA + +P +++ G W D+ +
Sbjct: 1152 YAVINHYGGMIGGHYTACAR-----------------LPNDRSSQRSDVG-WRLFDDSTV 1193
Query: 793 QVVPESRALSAQAYLLFYER 812
V ES+ ++ AY+LFY R
Sbjct: 1194 TTVDESQVVTRYAYVLFYRR 1213
>gi|223005906 X-linked ubiquitin thioesterase 27 [Homo sapiens]
Length = 438
Score = 80.1 bits (196), Expect = 8e-15
Identities = 52/204 (25%), Positives = 83/204 (40%), Gaps = 55/204 (26%)
Query: 619 SIQSCLYQFTSMELLMGNNKLLCENCTKNKQKYQEETSFAEKKVEGVYTNARKQLLISAV 678
++ CL +FT E L + K+ C +C Q YQE T KQL ++ +
Sbjct: 262 TLTDCLRRFTRPEHLGSSAKIKCGSC----QSYQEST---------------KQLTMNKL 302
Query: 679 PAVLILHLKRFHQAGLSLRKVNRHVDFPLMLDLAPFCSATCKNASVGDKVL--------- 729
P V H KRF + RK+ ++ FPL LD+ PF +++ ++ G L
Sbjct: 303 PVVACFHFKRFEHSAKQRRKITTYISFPLELDMTPFMASSKESRMNGQLQLPTNSGNNEN 362
Query: 730 -YGLYGIVEHSGSMREGHYTAYVKVRTPSRKLSEHNTKKKNVPGLKAADNESAGQWVHVS 788
Y L+ +V H G++ GHYT++++ QW
Sbjct: 363 KYSLFAVVNHQGTLESGHYTSFIR--------------------------HHKDQWFKCD 396
Query: 789 DTYLQVVPESRALSAQAYLLFYER 812
D + L ++ YLLFY +
Sbjct: 397 DAVITKASIKDVLDSEGYLLFYHK 420
Score = 60.1 bits (144), Expect = 8e-09
Identities = 59/198 (29%), Positives = 81/198 (40%), Gaps = 39/198 (19%)
Query: 187 LSVRGITNLGNTCFFNAVMQNLAQTYTLTDLMNEIKESSTKLKIFPSSDSQLDPLVVELS 246
+ +RG+ NLGNTCF N ++Q L T L D + PS + L V E+S
Sbjct: 75 IGLRGLINLGNTCFMNCIVQALTHTPILRDFFLSDRHRCE----MPSPELCL---VCEMS 127
Query: 247 RPGPLTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQQQDSQELLHYLLDAVR 306
+LF L+S + P P L + + A ++QQD+ E L LD +
Sbjct: 128 -------SLFRELYSGNPS---PHVPYKLLHLVWIHARHLAGYRQQDAHEFLIAALDVLH 177
Query: 307 TEETKRIQASILKAFNNPTTKTADDETRKKVKAYGKEGVKMNFIDRIFIGELTSTVMCEE 366
+ KA NNP ID+IF G L S V C+
Sbjct: 178 RHCKGD---DVGKAANNPNHCNC-------------------IIDQIFTGGLQSDVTCQA 215
Query: 367 CANISTVKDPFIDISLPI 384
C +ST DP DISL +
Sbjct: 216 CHGVSTTIDPCWDISLDL 233
>gi|150010639 ubiquitin thiolesterase 22 [Homo sapiens]
Length = 525
Score = 79.0 bits (193), Expect = 2e-14
Identities = 52/204 (25%), Positives = 83/204 (40%), Gaps = 55/204 (26%)
Query: 619 SIQSCLYQFTSMELLMGNNKLLCENCTKNKQKYQEETSFAEKKVEGVYTNARKQLLISAV 678
++ CL +FT E L + K+ C C YQE T KQL + +
Sbjct: 361 TLTDCLRRFTRPEHLGSSAKIKCSGC----HSYQEST---------------KQLTMKKL 401
Query: 679 PAVLILHLKRFHQAGLSLRKVNRHVDFPLMLDLAPFCSATCKNA----------SVGDKV 728
P V HLKRF + RK+ +V FPL LD+ PF +++ ++ S+ +
Sbjct: 402 PIVACFHLKRFEHSAKLRRKITTYVSFPLELDMTPFMASSKESRMNGQYQQPTDSLNNDN 461
Query: 729 LYGLYGIVEHSGSMREGHYTAYVKVRTPSRKLSEHNTKKKNVPGLKAADNESAGQWVHVS 788
Y L+ +V H G++ GHYT++++ + QW
Sbjct: 462 KYSLFAVVNHQGTLESGHYTSFIR--------------------------QHKDQWFKCD 495
Query: 789 DTYLQVVPESRALSAQAYLLFYER 812
D + L ++ YLLFY +
Sbjct: 496 DAIITKASIKDVLDSEGYLLFYHK 519
Score = 72.0 bits (175), Expect = 2e-12
Identities = 83/306 (27%), Positives = 119/306 (38%), Gaps = 56/306 (18%)
Query: 85 CLKCGFQGCGKNSESQHSLKHFKSSRTEPHCIIINLSTWIIWCYECDEKLSTHCNKKVLA 144
CL C F GC +H +H K+ R H + I+L I+C+ C + + K +
Sbjct: 76 CLYCVFFGC---FTKKHIHEHAKAKR---HNLAIDLMYGGIYCFLCQD----YIYDKDME 125
Query: 145 QIVDFLQKHASKTQTSAFSRIMKLCEEKCETDEIQKGGKCRNLS------VRGITNLGNT 198
I Q+ A K Q + K E + ++ K R ++ +RG+ NLGNT
Sbjct: 126 IIAKEEQRKAWKMQ-GVGEKFSTWEPTKRELELLKHNPKRRKITSNCTIGLRGLINLGNT 184
Query: 199 CFFNAVMQNLAQTYTLTDLMNEIKESSTKLKIFPSSDSQLDPLVVELSRPGPLTSALFLF 258
CF N ++Q L T L D + S LV E+ S+LF
Sbjct: 185 CFMNCIVQALTHTPLLRDFFLSDRHRC-------EMQSPSSCLVCEM-------SSLFQE 230
Query: 259 LHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQQQDSQELLHYLLDAVRTEETKRIQASIL 318
+S + P P L + + A ++QQD+ E L LD +
Sbjct: 231 FYS---GHRSPHIPYKLLHLVWTHARHLAGYEQQDAHEFLIAALDVLHRHCKGDDNG--- 284
Query: 319 KAFNNPTTKTADDETRKKVKAYGKEGVKMNFIDRIFIGELTSTVMCEECANISTVKDPFI 378
K NNP ID+IF G L S V C+ C +ST DPF
Sbjct: 285 KKANNPNHCNC-------------------IIDQIFTGGLQSDVTCQVCHGVSTTIDPFW 325
Query: 379 DISLPI 384
DISL +
Sbjct: 326 DISLDL 331
>gi|24234683 ubiquitin specific peptidase 11 [Homo sapiens]
Length = 963
Score = 78.6 bits (192), Expect = 2e-14
Identities = 56/203 (27%), Positives = 88/203 (43%), Gaps = 46/203 (22%)
Query: 611 YITTSKECSIQSCLYQFTSMELLMGNNKLLCENCTKNKQKYQEETSFAEKKVEGVYTNAR 670
Y+ +Q C+ FT++E L N C +C +++ A
Sbjct: 772 YVMKKAPVRLQECIELFTTVETLEKENPWYCPSCKQHQL-------------------AT 812
Query: 671 KQLLISAVPAVLILHLKRFHQAGLSLRKVNRHVDFPLM-LDLAPFCSATCKNASVGDKVL 729
K+L + +P +LI+HLKRF S K++ V+FP+ LD + F +N S +
Sbjct: 813 KKLDLWMLPEILIIHLKRFSYTKFSREKLDTLVEFPIRDLDFSEFVIQP-QNESNPELYK 871
Query: 730 YGLYGIVEHSGSMREGHYTAYVKVRTPSRKLSEHNTKKKNVPGLKAADNESAGQWVHVSD 789
Y L + H G MR+GHYT + A N+ +GQW + D
Sbjct: 872 YDLIAVSNHYGGMRDGHYTTF-------------------------ACNKDSGQWHYFDD 906
Query: 790 TYLQVVPESRALSAQAYLLFYER 812
+ V E++ S AY+LFY+R
Sbjct: 907 NSVSPVNENQIESKAAYVLFYQR 929
Score = 69.7 bits (169), Expect = 1e-11
Identities = 62/223 (27%), Positives = 98/223 (43%), Gaps = 31/223 (13%)
Query: 174 ETDEIQKGGKCRNLSVRGITNLGNTCFFNAVMQNLAQTYTLTD-LMNEIKESSTKLKIFP 232
E DE KG + G+TNLGNTCF N+ +Q L+ LT+ +N +
Sbjct: 297 EEDEDFKGQP----GICGLTNLGNTCFMNSALQCLSNVPQLTEYFLNNCYLEELNFR--- 349
Query: 233 SSDSQLDPLVVELSRPGPLTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQQQ 292
+PL ++ G + A + + P V N++ A +F +QQ
Sbjct: 350 ------NPLGMK----GEIAEAYADLVKQAWSGHHRSIVPHVFKNKVGHFASQFLGYQQH 399
Query: 293 DSQELLHYLLDAVRTEETKRIQ----ASILKAFNNPTTKTADDETRKKVKAYGKEGVKMN 348
DSQELL +LLD + E+ R++ + A P + A + + + +
Sbjct: 400 DSQELLSFLLDGLH-EDLNRVKKKEYVELCDAAGRPDQEVAQEAWQNHKRRND------S 452
Query: 349 FIDRIFIGELTSTVMCEECANISTVKDPF--IDISLPIIEERV 389
I F G ST++C +C N+S DPF + + LPI +RV
Sbjct: 453 VIVDTFHGLFKSTLVCPDCGNVSVTFDPFCYLSVPLPISHKRV 495
>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 78.2 bits (191), Expect = 3e-14
Identities = 62/209 (29%), Positives = 86/209 (41%), Gaps = 51/209 (24%)
Query: 603 AFQTLSQSYITTSKECSIQSCLYQFTSMELLMGNNKLLCENCTKNKQKYQEETSFAEKKV 662
AF LS +TSK C++Q CL F+ E L NN+ C +C + KK+
Sbjct: 948 AFMYLSLPLASTSK-CTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSL--------KKI 998
Query: 663 EGVYTNARKQLLISAVPAVLILHLKRFHQAGLSLRKVNRHVDFPLM-LDLAPFCSATCKN 721
E I +P VL++HLKRF G +K+ VDFPL LDL+ + N
Sbjct: 999 E-----------IWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKNN 1047
Query: 722 ASVGDKVLYGLYGIVEHSGSMREGHYTAYVKVRTPSRKLSEHNTKKKNVPGLKAADNESA 781
Y L+ + H G + GHYTAY K N +
Sbjct: 1048 LKK-----YNLFSVSNHYGGLDGGHYTAYCK-------------------------NAAR 1077
Query: 782 GQWVHVSDTYLQVVPESRALSAQAYLLFY 810
+W D + + S S+ AY+LFY
Sbjct: 1078 QRWFKFDDHEVSDISVSSVKSSAAYILFY 1106
Score = 60.5 bits (145), Expect = 6e-09
Identities = 51/204 (25%), Positives = 87/204 (42%), Gaps = 29/204 (14%)
Query: 188 SVRGITNLGNTCFFNAVMQNLAQTYTLTDLMN------EIKESSTKLKIFPSSDSQLDPL 241
++ G+ NLGNTC+ N+++Q L L D N +I S+
Sbjct: 775 ALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNL--------------- 819
Query: 242 VVELSRPGPLTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQQQDSQELLHYL 301
L G + + + ++ + +SPK + + +F + QQDSQELL +L
Sbjct: 820 ---LGHKGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFL 876
Query: 302 LDAVRTEETKRIQASILKAFNNPTTKTADDETRKKVKAYGK-EGVKMNFIDRIFIGELTS 360
+D + + K K NN D+ + A+ K + + + I +F G+ S
Sbjct: 877 MDGLHEDLNKADNRKRYKEENNDHL----DDFKAAEHAWQKHKQLNESIIVALFQGQFKS 932
Query: 361 TVMCEECANISTVKDPFIDISLPI 384
TV C C S + F+ +SLP+
Sbjct: 933 TVQCLTCHKKSRTFEAFMYLSLPL 956
>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 78.2 bits (191), Expect = 3e-14
Identities = 62/209 (29%), Positives = 86/209 (41%), Gaps = 51/209 (24%)
Query: 603 AFQTLSQSYITTSKECSIQSCLYQFTSMELLMGNNKLLCENCTKNKQKYQEETSFAEKKV 662
AF LS +TSK C++Q CL F+ E L NN+ C +C + KK+
Sbjct: 948 AFMYLSLPLASTSK-CTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSL--------KKI 998
Query: 663 EGVYTNARKQLLISAVPAVLILHLKRFHQAGLSLRKVNRHVDFPLM-LDLAPFCSATCKN 721
E I +P VL++HLKRF G +K+ VDFPL LDL+ + N
Sbjct: 999 E-----------IWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKNN 1047
Query: 722 ASVGDKVLYGLYGIVEHSGSMREGHYTAYVKVRTPSRKLSEHNTKKKNVPGLKAADNESA 781
Y L+ + H G + GHYTAY K N +
Sbjct: 1048 LKK-----YNLFSVSNHYGGLDGGHYTAYCK-------------------------NAAR 1077
Query: 782 GQWVHVSDTYLQVVPESRALSAQAYLLFY 810
+W D + + S S+ AY+LFY
Sbjct: 1078 QRWFKFDDHEVSDISVSSVKSSAAYILFY 1106
Score = 60.5 bits (145), Expect = 6e-09
Identities = 51/204 (25%), Positives = 87/204 (42%), Gaps = 29/204 (14%)
Query: 188 SVRGITNLGNTCFFNAVMQNLAQTYTLTDLMN------EIKESSTKLKIFPSSDSQLDPL 241
++ G+ NLGNTC+ N+++Q L L D N +I S+
Sbjct: 775 ALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNL--------------- 819
Query: 242 VVELSRPGPLTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQQQDSQELLHYL 301
L G + + + ++ + +SPK + + +F + QQDSQELL +L
Sbjct: 820 ---LGHKGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFL 876
Query: 302 LDAVRTEETKRIQASILKAFNNPTTKTADDETRKKVKAYGK-EGVKMNFIDRIFIGELTS 360
+D + + K K NN D+ + A+ K + + + I +F G+ S
Sbjct: 877 MDGLHEDLNKADNRKRYKEENNDHL----DDFKAAEHAWQKHKQLNESIIVALFQGQFKS 932
Query: 361 TVMCEECANISTVKDPFIDISLPI 384
TV C C S + F+ +SLP+
Sbjct: 933 TVQCLTCHKKSRTFEAFMYLSLPL 956
>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
Length = 1118
Score = 78.2 bits (191), Expect = 3e-14
Identities = 62/209 (29%), Positives = 86/209 (41%), Gaps = 51/209 (24%)
Query: 603 AFQTLSQSYITTSKECSIQSCLYQFTSMELLMGNNKLLCENCTKNKQKYQEETSFAEKKV 662
AF LS +TSK C++Q CL F+ E L NN+ C +C + KK+
Sbjct: 948 AFMYLSLPLASTSK-CTLQDCLRLFSKEEKLTDNNRFYCSHCRARRDSL--------KKI 998
Query: 663 EGVYTNARKQLLISAVPAVLILHLKRFHQAGLSLRKVNRHVDFPLM-LDLAPFCSATCKN 721
E I +P VL++HLKRF G +K+ VDFPL LDL+ + N
Sbjct: 999 E-----------IWKLPPVLLVHLKRFSYDGRWKQKLQTSVDFPLENLDLSQYVIGPKNN 1047
Query: 722 ASVGDKVLYGLYGIVEHSGSMREGHYTAYVKVRTPSRKLSEHNTKKKNVPGLKAADNESA 781
Y L+ + H G + GHYTAY K N +
Sbjct: 1048 LKK-----YNLFSVSNHYGGLDGGHYTAYCK-------------------------NAAR 1077
Query: 782 GQWVHVSDTYLQVVPESRALSAQAYLLFY 810
+W D + + S S+ AY+LFY
Sbjct: 1078 QRWFKFDDHEVSDISVSSVKSSAAYILFY 1106
Score = 60.5 bits (145), Expect = 6e-09
Identities = 51/204 (25%), Positives = 87/204 (42%), Gaps = 29/204 (14%)
Query: 188 SVRGITNLGNTCFFNAVMQNLAQTYTLTDLMN------EIKESSTKLKIFPSSDSQLDPL 241
++ G+ NLGNTC+ N+++Q L L D N +I S+
Sbjct: 775 ALTGLRNLGNTCYMNSILQCLCNAPHLADYFNRNCYQDDINRSNL--------------- 819
Query: 242 VVELSRPGPLTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQQQDSQELLHYL 301
L G + + + ++ + +SPK + + +F + QQDSQELL +L
Sbjct: 820 ---LGHKGEVAEEFGIIMKALWTGQYRYISPKDFKITIGKINDQFAGYSQQDSQELLLFL 876
Query: 302 LDAVRTEETKRIQASILKAFNNPTTKTADDETRKKVKAYGK-EGVKMNFIDRIFIGELTS 360
+D + + K K NN D+ + A+ K + + + I +F G+ S
Sbjct: 877 MDGLHEDLNKADNRKRYKEENNDHL----DDFKAAEHAWQKHKQLNESIIVALFQGQFKS 932
Query: 361 TVMCEECANISTVKDPFIDISLPI 384
TV C C S + F+ +SLP+
Sbjct: 933 TVQCLTCHKKSRTFEAFMYLSLPL 956
>gi|183396780 ubiquitin specific protease 20 [Homo sapiens]
Length = 914
Score = 77.8 bits (190), Expect = 4e-14
Identities = 54/195 (27%), Positives = 77/195 (39%), Gaps = 49/195 (25%)
Query: 619 SIQSCLYQFTSMELLMGNNKLLCENCTKNKQKYQEETSFAEKKVEGVYTNARKQLLISAV 678
+++ CL F + + L G+N CE C K + N K + +
Sbjct: 538 TLEDCLAAFFAADELKGDNMYSCERCKKLR-------------------NGVKYCKVLRL 578
Query: 679 PAVLILHLKRFHQAGLSLRKVNRHVDFPLM-LDLAPFCSATCKNASVGDKVLYGLYGIVE 737
P +L +HLKRF + K+N HV FPL LDL PF + C Y L ++
Sbjct: 579 PEILCIHLKRFRHEVMYSFKINSHVSFPLEGLDLRPFLAKEC----TSQITTYDLLSVIC 634
Query: 738 HSGSMREGHYTAYVKVRTPSRKLSEHNTKKKNVPGLKAADNESAGQWVHVSDTYLQVVPE 797
H G+ GHY AY N GQW D Y+ V E
Sbjct: 635 HHGTAGSGHYIAY-------------------------CQNVINGQWYEFDDQYVTEVHE 669
Query: 798 SRALSAQAYLLFYER 812
+ +A+ Y+LFY +
Sbjct: 670 TVVQNAEGYVLFYRK 684
Score = 70.5 bits (171), Expect = 6e-12
Identities = 63/265 (23%), Positives = 116/265 (43%), Gaps = 40/265 (15%)
Query: 81 DIWLCLK--CGFQGCGKNSESQHSLKHFKSSRTEPHCIIINLSTWIIWCYECDEKLSTHC 138
++W CL+ C + GCG+ S + HS H ++ + H + +NL+T+ +WCY C++++
Sbjct: 39 NLWACLQVACPYVGCGE-SFADHSTIHAQAKK---HNLTVNLTTFRLWCYACEKEV--FL 92
Query: 139 NKKVLAQIVDFLQKHASKTQTSAFSRIMKLC--------EEKCETDEIQKGGKCRNLSVR 190
+++ A ++ K S+ + S +K E + E D+++ G +
Sbjct: 93 EQRLAAPLLGSSSKF-SEQDSPPPSHPLKAVPIAVADEGESESEDDDLKPRG------LT 145
Query: 191 GITNLGNTCFFNAVMQNLAQTYTLTDLMNEIKESSTKLKIFPSSDSQLDPLVVELSRPGP 250
G+ NLGN+C+ NA +Q L+ LT E LV +P
Sbjct: 146 GMKNLGNSCYMNAALQALSNCPPLTQFFLE-----------------CGGLVRTDKKPAL 188
Query: 251 LTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQQQDSQELLHYLLDAVRTEET 310
S L + + P L + + P F+ + QQD+QE L L+D + E
Sbjct: 189 CKSYQKLVSEVWHKKRPSYVVPTSLSHGIKLVNPMFRGYAQQDTQEFLRCLMDQLHEELK 248
Query: 311 KRIQASILKAFNNPTTKTADDETRK 335
+ + A++ + + DE R+
Sbjct: 249 EPVVATVALTEARDSDSSDTDEKRE 273
Score = 34.7 bits (78), Expect = 0.37
Identities = 18/43 (41%), Positives = 23/43 (53%)
Query: 342 KEGVKMNFIDRIFIGELTSTVMCEECANISTVKDPFIDISLPI 384
KE + I IF G + S V C C +ST + F D+SLPI
Sbjct: 437 KEQRYRSVISDIFDGSILSLVQCLTCDRVSTTVETFQDLSLPI 479
>gi|183397136 ubiquitin specific protease 20 [Homo sapiens]
Length = 914
Score = 77.8 bits (190), Expect = 4e-14
Identities = 54/195 (27%), Positives = 77/195 (39%), Gaps = 49/195 (25%)
Query: 619 SIQSCLYQFTSMELLMGNNKLLCENCTKNKQKYQEETSFAEKKVEGVYTNARKQLLISAV 678
+++ CL F + + L G+N CE C K + N K + +
Sbjct: 538 TLEDCLAAFFAADELKGDNMYSCERCKKLR-------------------NGVKYCKVLRL 578
Query: 679 PAVLILHLKRFHQAGLSLRKVNRHVDFPLM-LDLAPFCSATCKNASVGDKVLYGLYGIVE 737
P +L +HLKRF + K+N HV FPL LDL PF + C Y L ++
Sbjct: 579 PEILCIHLKRFRHEVMYSFKINSHVSFPLEGLDLRPFLAKEC----TSQITTYDLLSVIC 634
Query: 738 HSGSMREGHYTAYVKVRTPSRKLSEHNTKKKNVPGLKAADNESAGQWVHVSDTYLQVVPE 797
H G+ GHY AY N GQW D Y+ V E
Sbjct: 635 HHGTAGSGHYIAY-------------------------CQNVINGQWYEFDDQYVTEVHE 669
Query: 798 SRALSAQAYLLFYER 812
+ +A+ Y+LFY +
Sbjct: 670 TVVQNAEGYVLFYRK 684
Score = 70.5 bits (171), Expect = 6e-12
Identities = 63/265 (23%), Positives = 116/265 (43%), Gaps = 40/265 (15%)
Query: 81 DIWLCLK--CGFQGCGKNSESQHSLKHFKSSRTEPHCIIINLSTWIIWCYECDEKLSTHC 138
++W CL+ C + GCG+ S + HS H ++ + H + +NL+T+ +WCY C++++
Sbjct: 39 NLWACLQVACPYVGCGE-SFADHSTIHAQAKK---HNLTVNLTTFRLWCYACEKEV--FL 92
Query: 139 NKKVLAQIVDFLQKHASKTQTSAFSRIMKLC--------EEKCETDEIQKGGKCRNLSVR 190
+++ A ++ K S+ + S +K E + E D+++ G +
Sbjct: 93 EQRLAAPLLGSSSKF-SEQDSPPPSHPLKAVPIAVADEGESESEDDDLKPRG------LT 145
Query: 191 GITNLGNTCFFNAVMQNLAQTYTLTDLMNEIKESSTKLKIFPSSDSQLDPLVVELSRPGP 250
G+ NLGN+C+ NA +Q L+ LT E LV +P
Sbjct: 146 GMKNLGNSCYMNAALQALSNCPPLTQFFLE-----------------CGGLVRTDKKPAL 188
Query: 251 LTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQQQDSQELLHYLLDAVRTEET 310
S L + + P L + + P F+ + QQD+QE L L+D + E
Sbjct: 189 CKSYQKLVSEVWHKKRPSYVVPTSLSHGIKLVNPMFRGYAQQDTQEFLRCLMDQLHEELK 248
Query: 311 KRIQASILKAFNNPTTKTADDETRK 335
+ + A++ + + DE R+
Sbjct: 249 EPVVATVALTEARDSDSSDTDEKRE 273
Score = 34.7 bits (78), Expect = 0.37
Identities = 18/43 (41%), Positives = 23/43 (53%)
Query: 342 KEGVKMNFIDRIFIGELTSTVMCEECANISTVKDPFIDISLPI 384
KE + I IF G + S V C C +ST + F D+SLPI
Sbjct: 437 KEQRYRSVISDIFDGSILSLVQCLTCDRVSTTVETFQDLSLPI 479
>gi|183397134 ubiquitin specific protease 20 [Homo sapiens]
Length = 914
Score = 77.8 bits (190), Expect = 4e-14
Identities = 54/195 (27%), Positives = 77/195 (39%), Gaps = 49/195 (25%)
Query: 619 SIQSCLYQFTSMELLMGNNKLLCENCTKNKQKYQEETSFAEKKVEGVYTNARKQLLISAV 678
+++ CL F + + L G+N CE C K + N K + +
Sbjct: 538 TLEDCLAAFFAADELKGDNMYSCERCKKLR-------------------NGVKYCKVLRL 578
Query: 679 PAVLILHLKRFHQAGLSLRKVNRHVDFPLM-LDLAPFCSATCKNASVGDKVLYGLYGIVE 737
P +L +HLKRF + K+N HV FPL LDL PF + C Y L ++
Sbjct: 579 PEILCIHLKRFRHEVMYSFKINSHVSFPLEGLDLRPFLAKEC----TSQITTYDLLSVIC 634
Query: 738 HSGSMREGHYTAYVKVRTPSRKLSEHNTKKKNVPGLKAADNESAGQWVHVSDTYLQVVPE 797
H G+ GHY AY N GQW D Y+ V E
Sbjct: 635 HHGTAGSGHYIAY-------------------------CQNVINGQWYEFDDQYVTEVHE 669
Query: 798 SRALSAQAYLLFYER 812
+ +A+ Y+LFY +
Sbjct: 670 TVVQNAEGYVLFYRK 684
Score = 70.5 bits (171), Expect = 6e-12
Identities = 63/265 (23%), Positives = 116/265 (43%), Gaps = 40/265 (15%)
Query: 81 DIWLCLK--CGFQGCGKNSESQHSLKHFKSSRTEPHCIIINLSTWIIWCYECDEKLSTHC 138
++W CL+ C + GCG+ S + HS H ++ + H + +NL+T+ +WCY C++++
Sbjct: 39 NLWACLQVACPYVGCGE-SFADHSTIHAQAKK---HNLTVNLTTFRLWCYACEKEV--FL 92
Query: 139 NKKVLAQIVDFLQKHASKTQTSAFSRIMKLC--------EEKCETDEIQKGGKCRNLSVR 190
+++ A ++ K S+ + S +K E + E D+++ G +
Sbjct: 93 EQRLAAPLLGSSSKF-SEQDSPPPSHPLKAVPIAVADEGESESEDDDLKPRG------LT 145
Query: 191 GITNLGNTCFFNAVMQNLAQTYTLTDLMNEIKESSTKLKIFPSSDSQLDPLVVELSRPGP 250
G+ NLGN+C+ NA +Q L+ LT E LV +P
Sbjct: 146 GMKNLGNSCYMNAALQALSNCPPLTQFFLE-----------------CGGLVRTDKKPAL 188
Query: 251 LTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQQQDSQELLHYLLDAVRTEET 310
S L + + P L + + P F+ + QQD+QE L L+D + E
Sbjct: 189 CKSYQKLVSEVWHKKRPSYVVPTSLSHGIKLVNPMFRGYAQQDTQEFLRCLMDQLHEELK 248
Query: 311 KRIQASILKAFNNPTTKTADDETRK 335
+ + A++ + + DE R+
Sbjct: 249 EPVVATVALTEARDSDSSDTDEKRE 273
Score = 34.7 bits (78), Expect = 0.37
Identities = 18/43 (41%), Positives = 23/43 (53%)
Query: 342 KEGVKMNFIDRIFIGELTSTVMCEECANISTVKDPFIDISLPI 384
KE + I IF G + S V C C +ST + F D+SLPI
Sbjct: 437 KEQRYRSVISDIFDGSILSLVQCLTCDRVSTTVETFQDLSLPI 479
>gi|14149627 ubiquitin specific peptidase 15 [Homo sapiens]
Length = 952
Score = 77.4 bits (189), Expect = 5e-14
Identities = 59/199 (29%), Positives = 95/199 (47%), Gaps = 25/199 (12%)
Query: 191 GITNLGNTCFFNAVMQNLAQTYTLTD-LMNEIKESSTKLKIFPSSDSQLDPLVVELSRPG 249
G++NLGNTCF N+ +Q L+ T LT+ +N+ + +PL + G
Sbjct: 261 GLSNLGNTCFMNSAIQCLSNTPPLTEYFLNDKYQEELNFD---------NPLGMR----G 307
Query: 250 PLTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQQQDSQELLHYLLDAVRTEE 309
+ + + M + ++P+ Q+ + AP+F +QQQD QELL +LLD + E+
Sbjct: 308 EIAKSYAELIKQMWSGKFSYVTPRAFKTQVGRFAPQFSGYQQQDCQELLAFLLDGLH-ED 366
Query: 310 TKRIQ----ASILKAFNNPTTKTADDETRKKVKAYGKEGVKMNFIDRIFIGELTSTVMCE 365
RI+ + A P A++ +K + I IF G ST++C
Sbjct: 367 LNRIRKKPYIQLKDADGRPDKVVAEEAWENHLKR------NDSIIVDIFHGLFKSTLVCP 420
Query: 366 ECANISTVKDPFIDISLPI 384
ECA IS DPF ++LP+
Sbjct: 421 ECAKISVTFDPFCYLTLPL 439
Score = 75.1 bits (183), Expect = 2e-13
Identities = 85/362 (23%), Positives = 140/362 (38%), Gaps = 72/362 (19%)
Query: 459 KNENLEMNGDSLMFASLMNSESRLNESPTDDSEKEASHSESNVDADSEPSESESASKQTG 518
K++N+ NG + + SE +E P D+S ++ N ++ SE S + G
Sbjct: 606 KDQNINGNGPNGIHEEGSPSEMETDE-PDDESSQDQELPSENENSQSEDSVGGDNDSENG 664
Query: 519 LFRSSSGSGVQPDGPLYPLSAGKLLYTKETD-----SGDKEMAEAISELRLSSTVTGDQD 573
L + G Q G L + TD + + +LRL D
Sbjct: 665 LCTEDTCKG-QLTGHKKRLFTFQFNNLGNTDINYIKDDTRHIRFDDRQLRLDERSFLALD 723
Query: 574 FDRENQPLNISNNLC--FLEGKHLRSYSPQNAFQTLSQSYITTSKECSIQSCLYQFTSME 631
+D + + N F + + + P+ F L + C+ FT+ E
Sbjct: 724 WDPDLKKRYFDENAAEDFEKHESVEYKPPKKPFVKL-------------KDCIELFTTKE 770
Query: 632 LLMGNNKLLCENCTKNKQKYQEETSFAEKKVEGVYTNARKQLLISAVPAVLILHLKRFHQ 691
L + C NC +++Q A K+L + ++P VL++HLKRF
Sbjct: 771 KLGAEDPWYCPNCKEHQQ-------------------ATKKLDLWSLPPVLVVHLKRFSY 811
Query: 692 AGLSLRKVNRHVDFPLM-LDLAPFCSATCKNASVGDKVLYGLYGIVEHSGSMREGHYTAY 750
+ K++ VDFP+ LD++ F N + G Y L + H G M GHYTA+
Sbjct: 812 SRYMRDKLDTLVDFPINDLDMSEFLI----NPNAG-PCRYNLIAVSNHYGGMGGGHYTAF 866
Query: 751 VKVRTPSRKLSEHNTKKKNVPGLKAADNESAGQWVHVSDTYLQVVPESRALSAQAYLLFY 810
K N+ G+W + D+ + E + +S AY+LFY
Sbjct: 867 AK-------------------------NKDDGKWYYFDDSSVSTASEDQIVSKAAYVLFY 901
Query: 811 ER 812
+R
Sbjct: 902 QR 903
>gi|122114651 ubiquitin specific peptidase 36 [Homo sapiens]
Length = 1123
Score = 75.5 bits (184), Expect = 2e-13
Identities = 69/254 (27%), Positives = 105/254 (41%), Gaps = 63/254 (24%)
Query: 568 VTGDQDFDRENQPLNISNNLCFLEGKHLRSYSPQNAFQTLSQSY-------ITTSKECSI 620
+ G DR+ Q + + + G +LRS + +++S +Y + + +I
Sbjct: 225 LNGCAKLDRQTQATTLVHQIF---GGYLRSRVKCSVCKSVSDTYDPYLDVALEIRQAANI 281
Query: 621 QSCLYQFTSMELLMGNNKLLCENCTKNKQKYQEETSFAEKKVEGVYTNARKQLLISAVPA 680
L F ++L G N +C C +KKV A K+ I
Sbjct: 282 VRALELFVKADVLSGENAYMCAKC--------------KKKVP-----ASKRFTIHRTSN 322
Query: 681 VLILHLKRFHQAGLSLRKVNRHVDFPLMLDLAPFCSATCKNASVGDKVLYGLYGIVEHSG 740
VL L LKRF A S K+ + V +P L++ P+ S + GD V+YGLY ++ HSG
Sbjct: 323 VLTLSLKRF--ANFSGGKITKDVGYPEFLNIRPYMSQ-----NNGDPVMYGLYAVLVHSG 375
Query: 741 -SMREGHYTAYVKVRTPSRKLSEHNTKKKNVPGLKAADNESAGQWVHVSDTYLQVVPESR 799
S GHY YVK S GQW ++D+ +
Sbjct: 376 YSCHAGHYYCYVKA--------------------------SNGQWYQMNDSLVHSSNVKV 409
Query: 800 ALSAQAYLLFYERV 813
L+ QAY+LFY R+
Sbjct: 410 VLNQQAYVLFYLRI 423
Score = 50.4 bits (119), Expect = 6e-06
Identities = 50/195 (25%), Positives = 77/195 (39%), Gaps = 43/195 (22%)
Query: 191 GITNLGNTCFFNAVMQNLAQTYTLTD-LMNEIKESSTKLKIFPSSDSQLDPLVVELSRPG 249
G+ NLGNTCF NA +Q L T L + L+++ S F + +V + G
Sbjct: 123 GLHNLGNTCFLNATIQCLTYTPPLANYLLSKEHARSCHQGSFCMLCVMQNHIVQAFANSG 182
Query: 250 PLTSALFLFLHSMKETEKGPLSPKVLFNQLCQKAPRFKDFQQQDSQELLHYLLDAVRTEE 309
+ P L + A F+ Q+D+ E L Y +DA++
Sbjct: 183 ------------------NAIKPVSFIRDLKKIARHFRFGNQEDAHEFLRYTIDAMQ--- 221
Query: 310 TKRIQASILKAFNNPTTKTADDETRKKVKAYGKEGVKMNFIDRIFIGELTSTVMCEECAN 369
KA N K D +T+ + +IF G L S V C C +
Sbjct: 222 ---------KACLNGCAKL-DRQTQATT-----------LVHQIFGGYLRSRVKCSVCKS 260
Query: 370 ISTVKDPFIDISLPI 384
+S DP++D++L I
Sbjct: 261 VSDTYDPYLDVALEI 275
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.129 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,994,128
Number of Sequences: 37866
Number of extensions: 1324344
Number of successful extensions: 5946
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 86
Number of HSP's successfully gapped in prelim test: 86
Number of HSP's that attempted gapping in prelim test: 5258
Number of HSP's gapped (non-prelim): 461
length of query: 814
length of database: 18,247,518
effective HSP length: 111
effective length of query: 703
effective length of database: 14,044,392
effective search space: 9873207576
effective search space used: 9873207576
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.