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Search of human proteins with 32880206
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32880206 cadherin-like 24 isoform 1 [Homo sapiens]
(819 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32880206 cadherin-like 24 isoform 1 [Homo sapiens] 1659 0.0
gi|32880203 cadherin-like 24 isoform 2 [Homo sapiens] 1557 0.0
gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens] 838 0.0
gi|16306539 cadherin 8, type 2 preproprotein [Homo sapiens] 803 0.0
gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens] 755 0.0
gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens] 743 0.0
gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens] 738 0.0
gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens] 738 0.0
gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens] 733 0.0
gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens] 733 0.0
gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens] 726 0.0
gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens] 709 0.0
gi|16753221 cadherin 22 precursor [Homo sapiens] 655 0.0
gi|12656655 cadherin 19, type 2 preproprotein [Homo sapiens] 538 e-152
gi|166362713 cadherin 5, type 2 preproprotein [Homo sapiens] 494 e-139
gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens] 367 e-101
gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens] 364 e-100
gi|4826669 cadherin 15 preproprotein [Homo sapiens] 331 1e-90
gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens] 319 7e-87
gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens] 279 7e-75
gi|4502719 cadherin 13 preproprotein [Homo sapiens] 213 6e-55
gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens] 203 5e-52
gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo sapi... 203 5e-52
gi|29570800 cadherin-like 26 isoform a [Homo sapiens] 194 2e-49
gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo sap... 191 2e-48
gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo sap... 191 2e-48
gi|16933557 dachsous 1 precursor [Homo sapiens] 187 3e-47
gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo sapi... 184 4e-46
gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo sapi... 184 4e-46
gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens] 182 8e-46
>gi|32880206 cadherin-like 24 isoform 1 [Homo sapiens]
Length = 819
Score = 1659 bits (4297), Expect = 0.0
Identities = 819/819 (100%), Positives = 819/819 (100%)
Query: 1 MWGLVRLLLAWLGGWGCMGRLAAPARAWAGSREHPGPALLRTRRSWVWNQFFVIEEYAGP 60
MWGLVRLLLAWLGGWGCMGRLAAPARAWAGSREHPGPALLRTRRSWVWNQFFVIEEYAGP
Sbjct: 1 MWGLVRLLLAWLGGWGCMGRLAAPARAWAGSREHPGPALLRTRRSWVWNQFFVIEEYAGP 60
Query: 61 EPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEATGNIHVTKSLDREEKAQYVLLAQ 120
EPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEATGNIHVTKSLDREEKAQYVLLAQ
Sbjct: 61 EPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEATGNIHVTKSLDREEKAQYVLLAQ 120
Query: 121 AVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDP 180
AVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDP
Sbjct: 121 AVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDP 180
Query: 181 SYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLS 240
SYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLS
Sbjct: 181 SYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLS 240
Query: 241 GSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILD 300
GSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILD
Sbjct: 241 GSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILD 300
Query: 301 GEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVAS 360
GEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVAS
Sbjct: 301 GEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVAS 360
Query: 361 VRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAADLDSPASPIRYSILPHSDPER 420
VRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAADLDSPASPIRYSILPHSDPER
Sbjct: 361 VRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAADLDSPASPIRYSILPHSDPER 420
Query: 421 CFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQ 480
CFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQ
Sbjct: 421 CFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQ 480
Query: 481 RSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRA 540
RSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRA
Sbjct: 481 RSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRA 540
Query: 541 LDRDEVGNSSHVSFQGPLGPDANFTVQDNRDGSASLLLPSRPAPPRHAPYLVPIELWDWG 600
LDRDEVGNSSHVSFQGPLGPDANFTVQDNRDGSASLLLPSRPAPPRHAPYLVPIELWDWG
Sbjct: 541 LDRDEVGNSSHVSFQGPLGPDANFTVQDNRDGSASLLLPSRPAPPRHAPYLVPIELWDWG 600
Query: 601 QPALSSTATVTVSVCRCQPDGSVASCWPEAHLSAAGLSTGALLAIITCVGALLALVVLFV 660
QPALSSTATVTVSVCRCQPDGSVASCWPEAHLSAAGLSTGALLAIITCVGALLALVVLFV
Sbjct: 601 QPALSSTATVTVSVCRCQPDGSVASCWPEAHLSAAGLSTGALLAIITCVGALLALVVLFV 660
Query: 661 ALRRQKQEALMVLEEEDVRENIITYDDEGGGEEDTEAFDITALQNPDGAAPPAPGPPARR 720
ALRRQKQEALMVLEEEDVRENIITYDDEGGGEEDTEAFDITALQNPDGAAPPAPGPPARR
Sbjct: 661 ALRRQKQEALMVLEEEDVRENIITYDDEGGGEEDTEAFDITALQNPDGAAPPAPGPPARR 720
Query: 721 DVLPRARVSRQPRPPGPADVAQLLALRLREADEDPGVPPYDSVQVYGYEGRGSSCGSLSS 780
DVLPRARVSRQPRPPGPADVAQLLALRLREADEDPGVPPYDSVQVYGYEGRGSSCGSLSS
Sbjct: 721 DVLPRARVSRQPRPPGPADVAQLLALRLREADEDPGVPPYDSVQVYGYEGRGSSCGSLSS 780
Query: 781 LGSGSEAGGAPGPAEPLDDWGPLFRTLAELYGAKEPPAP 819
LGSGSEAGGAPGPAEPLDDWGPLFRTLAELYGAKEPPAP
Sbjct: 781 LGSGSEAGGAPGPAEPLDDWGPLFRTLAELYGAKEPPAP 819
>gi|32880203 cadherin-like 24 isoform 2 [Homo sapiens]
Length = 781
Score = 1557 bits (4031), Expect = 0.0
Identities = 781/819 (95%), Positives = 781/819 (95%), Gaps = 38/819 (4%)
Query: 1 MWGLVRLLLAWLGGWGCMGRLAAPARAWAGSREHPGPALLRTRRSWVWNQFFVIEEYAGP 60
MWGLVRLLLAWLGGWGCMGRLAAPARAWAGSREHPGPALLRTRRSWVWNQFFVIEEYAGP
Sbjct: 1 MWGLVRLLLAWLGGWGCMGRLAAPARAWAGSREHPGPALLRTRRSWVWNQFFVIEEYAGP 60
Query: 61 EPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEATGNIHVTKSLDREEKAQYVLLAQ 120
EPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEATGNIHVTKSLDREEKAQYVLLAQ
Sbjct: 61 EPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEATGNIHVTKSLDREEKAQYVLLAQ 120
Query: 121 AVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDP 180
AVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDP
Sbjct: 121 AVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDP 180
Query: 181 SYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLS 240
SYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLS
Sbjct: 181 SYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLS 240
Query: 241 GSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILD 300
GSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILD
Sbjct: 241 GSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILD 300
Query: 301 GEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVAS 360
GEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVAS
Sbjct: 301 GEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVAS 360
Query: 361 VRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAADLDSPASPIRYSILPHSDPER 420
VRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAADLDSPASPIRYSILPHSDPER
Sbjct: 361 VRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAADLDSPASPIRYSILPHSDPER 420
Query: 421 CFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQ 480
CFSIQPEEGTIHTAAPLDREARAWHNLTVLATEL
Sbjct: 421 CFSIQPEEGTIHTAAPLDREARAWHNLTVLATEL-------------------------- 454
Query: 481 RSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRA 540
DSSAQASRVQVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRA
Sbjct: 455 ------------DSSAQASRVQVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRA 502
Query: 541 LDRDEVGNSSHVSFQGPLGPDANFTVQDNRDGSASLLLPSRPAPPRHAPYLVPIELWDWG 600
LDRDEVGNSSHVSFQGPLGPDANFTVQDNRDGSASLLLPSRPAPPRHAPYLVPIELWDWG
Sbjct: 503 LDRDEVGNSSHVSFQGPLGPDANFTVQDNRDGSASLLLPSRPAPPRHAPYLVPIELWDWG 562
Query: 601 QPALSSTATVTVSVCRCQPDGSVASCWPEAHLSAAGLSTGALLAIITCVGALLALVVLFV 660
QPALSSTATVTVSVCRCQPDGSVASCWPEAHLSAAGLSTGALLAIITCVGALLALVVLFV
Sbjct: 563 QPALSSTATVTVSVCRCQPDGSVASCWPEAHLSAAGLSTGALLAIITCVGALLALVVLFV 622
Query: 661 ALRRQKQEALMVLEEEDVRENIITYDDEGGGEEDTEAFDITALQNPDGAAPPAPGPPARR 720
ALRRQKQEALMVLEEEDVRENIITYDDEGGGEEDTEAFDITALQNPDGAAPPAPGPPARR
Sbjct: 623 ALRRQKQEALMVLEEEDVRENIITYDDEGGGEEDTEAFDITALQNPDGAAPPAPGPPARR 682
Query: 721 DVLPRARVSRQPRPPGPADVAQLLALRLREADEDPGVPPYDSVQVYGYEGRGSSCGSLSS 780
DVLPRARVSRQPRPPGPADVAQLLALRLREADEDPGVPPYDSVQVYGYEGRGSSCGSLSS
Sbjct: 683 DVLPRARVSRQPRPPGPADVAQLLALRLREADEDPGVPPYDSVQVYGYEGRGSSCGSLSS 742
Query: 781 LGSGSEAGGAPGPAEPLDDWGPLFRTLAELYGAKEPPAP 819
LGSGSEAGGAPGPAEPLDDWGPLFRTLAELYGAKEPPAP
Sbjct: 743 LGSGSEAGGAPGPAEPLDDWGPLFRTLAELYGAKEPPAP 781
>gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens]
Length = 796
Score = 838 bits (2164), Expect = 0.0
Identities = 432/790 (54%), Positives = 554/790 (70%), Gaps = 54/790 (6%)
Query: 36 GPALLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVID 95
G L R++R WVWNQFFVIEEY GP+PVL+G+LHSD+D G+G KY+L+GEGAGT+FVID
Sbjct: 45 GQVLQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVID 104
Query: 96 EATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPY 155
+ +GNIH TK+LDREE+AQY L+AQAVDR +NRPLEPPSEFI+KVQDINDNPP F Y
Sbjct: 105 DKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHETY 164
Query: 156 HATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNM 215
HA VPE SNVGTSVIQVTA DADDP+YGNSAKLVY++L+G P+FSV+ QTG++RTA+PNM
Sbjct: 165 HANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRTALPNM 224
Query: 216 DRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPG 275
DRE +EE+ VVIQAKDMGGHMGGLSG+T VT+TL+DVNDNPPKFPQS+YQ SV E A PG
Sbjct: 225 DREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPG 284
Query: 276 TLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYS 335
VGR++A+DPD+G+N L+ Y+I+DG+G E+F I+TD + ++G++ ++KP+DFE++R+YS
Sbjct: 285 EEVGRVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPVDFETKRAYS 344
Query: 336 FRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQ 395
+VEA N IDP ++ GPFKD +V+++V+DA EPP F +Y V EN A GT+VG+
Sbjct: 345 LKVEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQENAAAGTVVGR 404
Query: 396 ISAADLDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELG 455
+ A D D+ SPIRYSI H+D +R F+I PE+G I T PLDRE AW N+TV A E+
Sbjct: 405 VHAKDPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNITVFAAEI- 463
Query: 456 WSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAP 515
+ Q ++V VAI+ LD NDNAP
Sbjct: 464 -------------------------------------HNRHQEAKVPVAIRVLDVNDNAP 486
Query: 516 QLAEPYDTFVCDS----AAPGQLIQVIRALDRDEVGNSSHVSFQGP--LGPDANFTVQDN 569
+ A PY+ F+C+S Q I I A D+D+ N F P + + NFTV+DN
Sbjct: 487 KFAAPYEGFICESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPNFTVRDN 546
Query: 570 RDGSASLLLPSRP-APPRHAPYLVPIELWDWGQPALSSTATVTVSVCRCQPDGSVASCWP 628
RD +A + + + YL+PI + D G P +SST T+T+ VC C +G++ SC
Sbjct: 547 RDNTAGVYARRGGFSRQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNA 606
Query: 629 EAHLSAAGLSTGALLAIITCVGALLALVVLFVALRRQKQEALMVLEEEDVRENIITYDDE 688
EA++ AGLSTGAL+AI+ C+ LL +VVLFV LRRQK+E L+V EEEDVRENIITYDDE
Sbjct: 607 EAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEPLIVFEEEDVRENIITYDDE 666
Query: 689 GGGEEDTEAFDITALQNPDGAAPPAPGPPARRDVLPRARVSRQP--RP-PGPADVAQLLA 745
GGGEEDTEAFDI LQNPDG P R+D+ P + +P RP P DV +
Sbjct: 667 GGGEEDTEAFDIATLQNPDGINGFIP----RKDIKPEYQYMPRPGLRPAPNSVDVDDFIN 722
Query: 746 LRLREADEDPGVPPYDSVQVYGYEGRGSSCGSLSSLGSGSEAGGAPGPAEPLDDWGPLFR 805
R++EAD DP PPYDS+Q+YGYEGRGS GSLSSL S + + L +WGP F+
Sbjct: 723 TRIQEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDL--DYDYLQNWGPRFK 780
Query: 806 TLAELYGAKE 815
LA+LYG+K+
Sbjct: 781 KLADLYGSKD 790
>gi|16306539 cadherin 8, type 2 preproprotein [Homo sapiens]
Length = 799
Score = 803 bits (2073), Expect = 0.0
Identities = 409/780 (52%), Positives = 534/780 (68%), Gaps = 44/780 (5%)
Query: 39 LLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEAT 98
L R++R WVWNQ FV+EE++GPEP+L+G+LH+D+D G + KY+L+G+GAGT+F I++ T
Sbjct: 56 LNRSKRGWVWNQMFVLEEFSGPEPILVGRLHTDLDPGSKKIKYILSGDGAGTIFQINDVT 115
Query: 99 GNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHAT 158
G+IH K LDREEKA+Y L AQAVD +++PLEPPSEFIIKVQDINDN P F GPYHAT
Sbjct: 116 GDIHAIKRLDREEKAEYTLTAQAVDWETSKPLEPPSEFIIKVQDINDNAPEFLNGPYHAT 175
Query: 159 VPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNMDRE 218
VPEMS +GTSV VTA DADDP YGNSAKLVY++L+G P+FS++P+T +++TA+PNMDRE
Sbjct: 176 VPEMSILGTSVTNVTATDADDPVYGNSAKLVYSILEGQPYFSIEPETAIIKTALPNMDRE 235
Query: 219 TQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLV 278
+EE+LVVIQAKDMGGH GGLSG+TT+TVTL+DVNDNPPKF QSLY FSV E GT +
Sbjct: 236 AKEEYLVVIQAKDMGGHSGGLSGTTTLTVTLTDVNDNPPKFAQSLYHFSVPEDVVLGTAI 295
Query: 279 GRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRV 338
GR++A D D+G+NA +Y I+DG+G+ F I++D Q +DG++ +RKPLDFE+++SY+ +V
Sbjct: 296 GRVKANDQDIGENAQSSYDIIDGDGTALFEITSDAQAQDGIIRLRKPLDFETKKSYTLKV 355
Query: 339 EATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISA 398
EA N IDP + RGPFKD A+V++ V+DA EPP F+ Y L V EN A +++GQ++A
Sbjct: 356 EAANVHIDPRFSGRGPFKDTATVKIVVEDADEPPVFSSPTYLLEVHENAALNSVIGQVTA 415
Query: 399 ADLDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSW 458
D D +SPIR+SI H+D ER F+I ++G I A PLDRE WHN+T++ATE+
Sbjct: 416 RDPDITSSPIRFSIDRHTDLERQFNINADDGKITLATPLDRELSVWHNITIIATEI---- 471
Query: 459 GPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQLA 518
+ +Q SRV VAI+ LD NDNAP+ A
Sbjct: 472 ----------------------------------RNHSQISRVPVAIKVLDVNDNAPEFA 497
Query: 519 EPYDTFVCDSAAPGQLIQVIRALDRDEVGNSSH--VSFQGPLGPDANFTVQDNRDGSASL 576
Y+ F+C++ PGQ+IQ + A+D+D+ N + S + + NFT++ N D S S+
Sbjct: 498 SEYEAFLCENGKPGQVIQTVSAMDKDDPKNGHYFLYSLLPEMVNNPNFTIKKNEDNSLSI 557
Query: 577 LLPSRP-APPRHAPYLVPIELWDWGQPALSSTATVTVSVCRCQPDGSVASCWPEAHLSAA 635
L + YL+PI + D G P LSST+T+T+ VC C DG V SC EA++
Sbjct: 558 LAKHNGFNRQKQEVYLLPIIISDSGNPPLSSTSTLTIRVCGCSNDGVVQSCNVEAYVLPI 617
Query: 636 GLSTGALLAIITCVGALLALVVLFVALRRQKQEALMVLEEEDVRENIITYDDEGGGEEDT 695
GLS GAL+AI+ C+ LL +VVLFV LRR K E L++ ++EDVRENII YDDEGGGEEDT
Sbjct: 618 GLSMGALIAILACIILLLVIVVLFVTLRRHKNEPLIIKDDEDVRENIIRYDDEGGGEEDT 677
Query: 696 EAFDITALQNPDGAAPPAPGPPARRDVLPRARVSRQPRPPGPADVAQLLALRLREADEDP 755
EAFDI LQNPDG P + D+ R P P G DV + + +RL EAD DP
Sbjct: 678 EAFDIATLQNPDGINGFLPRKDIKPDLQFMPRQGLAPVPNG-VDVDEFINVRLHEADNDP 736
Query: 756 GVPPYDSVQVYGYEGRGSSCGSLSSLGSGSEAGGAPGPAEPLDDWGPLFRTLAELYGAKE 815
PPYDS+Q+YGYEGRGS GSLSSL S + + L DWGP F+ L ELY E
Sbjct: 737 TAPPYDSIQIYGYEGRGSVAGSLSSL--ESTTSDSDQNFDYLSDWGPRFKRLGELYSVGE 794
>gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 755 bits (1950), Expect = 0.0
Identities = 398/783 (50%), Positives = 523/783 (66%), Gaps = 55/783 (7%)
Query: 41 RTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEATGN 100
R +R WVWNQFFV+EE+ GP+P +GKLHS+ D+G+G KY+LTGEGAGT+F+ID+ TG+
Sbjct: 50 RPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGTIFIIDDTTGD 109
Query: 101 IHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVP 160
IH TKSLDRE+K YVL AQA+DR +N+PLEP SEFIIKVQDINDN P F GPY TVP
Sbjct: 110 IHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYIVTVP 169
Query: 161 EMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNMDRETQ 220
EMS++GTSV+QVTA DADDP+YGNSA++VY++L G P+FSVDP+TGV+RTA+ NMDRE +
Sbjct: 170 EMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQPYFSVDPKTGVIRTALHNMDREAR 229
Query: 221 EEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGR 280
E + VVIQAKDM G +GGLSGSTTV +TL+DVNDNPP+FPQ YQ V E+A G+ VG+
Sbjct: 230 EHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESAQVGSAVGK 289
Query: 281 LRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEA 340
++A D D G NA M YSI++G+G FSISTD + R+G+L+++KPL++E ++SY+ +E
Sbjct: 290 IKANDADTGSNADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNYEKKKSYTLNIEG 349
Query: 341 TNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAAD 400
NT +D + GPFKD +++ V D EPP F+ +Y + V EN GT+VG + A D
Sbjct: 350 ANTHLDFRFSHLGPFKDATMLKIIVGDVDEPPLFSMPSYLMEVYENAKIGTVVGTVLAQD 409
Query: 401 LDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGP 460
DS S +RY I + + +R F+I GTI T LDRE W+N+TV A+E+
Sbjct: 410 PDSTNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDREETPWYNITVTASEI------ 463
Query: 461 ERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQLAEP 520
D+ S V V I+ LD NDN P+LA
Sbjct: 464 --------------------------------DNPDLLSHVTVGIRVLDVNDNPPELARE 491
Query: 521 YDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSF----QGPLGPDANFTVQDNRDGSASL 576
YD VC+++ PGQ+I I A D+D+ N +F + P+ P NFT++DN D +AS+
Sbjct: 492 YDIIVCENSKPGQVIHTISATDKDDFANGPRFNFFLDERLPVNP--NFTLKDNEDNTASI 549
Query: 577 LLPSRP-APPRHAPYLVPIELWDWGQPALSSTATVTVSVCRCQPDGSVASCWPEAHLSAA 635
L R + Y +PI + D G P+LSS++T+T+ VC C+ DG V +C EA LS+A
Sbjct: 550 LTRRRRFSRTVQDVYYLPIMISDGGIPSLSSSSTLTIRVCACERDGRVRTCHAEAFLSSA 609
Query: 636 GLSTGALLAIITCVGALLALVVLFVALRRQKQEALMVLEEEDVRENIITYDDEGGGEEDT 695
GLSTGAL+AI+ CV LLA+VVLF+ LRR K+E L ++ EEDVREN++TYDDEGGGEEDT
Sbjct: 610 GLSTGALIAILLCVLILLAIVVLFITLRRSKKEPL-IISEEDVRENVVTYDDEGGGEEDT 668
Query: 696 EAFDITALQNPDGAAPPAPGPPARRDVLPRARVSRQPRPPG---PADVAQLLALRLREAD 752
EAFDITAL+NP A RRD+ P +++ + + DV + + RL EAD
Sbjct: 669 EAFDITALRNPSAAEE----LKYRRDIRPEVKLTPRHQTSSTLESIDVQEFIKQRLAEAD 724
Query: 753 EDPGVPPYDSVQVYGYEGRGSSCGSLSSLGSGSEAGGAPGPAEPLDDWGPLFRTLAELYG 812
DP VPPYDS+Q Y YEG+ S GS+SSL S + + L DWGP F+ LAELYG
Sbjct: 725 LDPSVPPYDSLQTYAYEGQRSEAGSISSLDSATTQ--SDQDYHYLGDWGPEFKKLAELYG 782
Query: 813 AKE 815
E
Sbjct: 783 EIE 785
>gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens]
Length = 801
Score = 743 bits (1919), Expect = 0.0
Identities = 397/787 (50%), Positives = 520/787 (66%), Gaps = 51/787 (6%)
Query: 41 RTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEATGN 100
RT+RSWVWNQFFV+EEY G +P+ +GKLHSD+DRG+G KY+L+GEGAG VF ID+ TG+
Sbjct: 56 RTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGIVFTIDDTTGD 115
Query: 101 IHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVP 160
IH + LDREE+AQY L AQA+DR + RP+EP SEFIIK+QDINDN P F GPY ATVP
Sbjct: 116 IHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLDGPYVATVP 175
Query: 161 EMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNMDRETQ 220
EMS VGTSVIQVTA DADDP+YGNSA++VY++L G P+FSVD +TGV+RTA+ NMDRE +
Sbjct: 176 EMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQPYFSVDSKTGVIRTALMNMDREAK 235
Query: 221 EEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGR 280
E + V+IQAKDMGG +GGL+G+TTV +TLSDVNDNPP+FPQ YQ SV+E+A + VGR
Sbjct: 236 EYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGR 295
Query: 281 LRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEA 340
+ A+D D G NA M Y+I+DG+G++AF ISTD + G++TV+KPL FES++SY+ +VE
Sbjct: 296 VFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEG 355
Query: 341 TNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAAD 400
N ++ +L GPF+D +V ++V+D EPP F Y + VPE+ A GT + ISA D
Sbjct: 356 ANPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVPEDVAIGTTIQIISAKD 415
Query: 401 LDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGP 460
D + IRYSI SDP R F + G + TA PLDRE +WHN+TVLA E+
Sbjct: 416 PDVTNNSIRYSIDRSSDPGRFFYVDITTGALMTARPLDREEFSWHNITVLAMEM------ 469
Query: 461 ERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQLAEP 520
++ +Q V V I+ LD NDNAP+
Sbjct: 470 --------------------------------NNPSQVGSVPVTIKVLDVNDNAPEFPRF 497
Query: 521 YDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQGPLGPDA----NFTVQDNRDGSASL 576
Y+ FVC++A GQLIQ + A+D+D+ N H F L P+A NFT++DN+D +A +
Sbjct: 498 YEAFVCENAKAGQLIQTVSAVDQDDPRNGQH--FYYSLAPEAANNPNFTIRDNQDNTARI 555
Query: 577 LL-PSRPAPPRHAPYLVPIELWDWGQPALSSTATVTVSVCRCQPDGSVASCWPEAHLSAA 635
L S + + +PI + D GQP LSST T+T+ VC C DG V SC PEA++
Sbjct: 556 LTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDDGHVMSCSPEAYMLPV 615
Query: 636 GLSTGALLAIITCVGALLALVVLFVALRRQKQEALMVLEEEDVRENIITYDDEGGGEEDT 695
LS GAL+AI+ C+ LL LV+L +++RR +++ ++ +EE++ ENI+ YDDEGGGEEDT
Sbjct: 616 SLSRGALIAILACIFVLLVLVLLILSMRRHRKQPYIIDDEENIHENIVRYDDEGGGEEDT 675
Query: 696 EAFDITALQNPDGAAPPAPGPPARRDVLPRARVSRQPRPPGPA---DVAQLLALRLREAD 752
EAFDI A+ NP A A P R+D+LP + P A V + +L EAD
Sbjct: 676 EAFDIAAMWNPREAQAGA-APKTRQDMLPEIESLSRYVPQTCAVNSTVHSYVLAKLYEAD 734
Query: 753 EDPGVPPYDSVQVYGYEGRGSSCGSLSSLGSGSEAGGAPGPAEPLDDWGPLFRTLAELYG 812
D PP+DS+Q Y +EG GS GSLSSL S + + + L DWGP FR LAELYG
Sbjct: 735 MDLWAPPFDSLQTYMFEGDGSVAGSLSSLQSAT--SDSEQSFDFLTDWGPRFRKLAELYG 792
Query: 813 AKEPPAP 819
A E PAP
Sbjct: 793 ASEGPAP 799
>gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 738 bits (1906), Expect = 0.0
Identities = 381/782 (48%), Positives = 523/782 (66%), Gaps = 55/782 (7%)
Query: 39 LLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEAT 98
L R++RSW+WNQFF++EEY G + +GKLHSD DRG+G KY+L+G+GAG +F+I+E T
Sbjct: 48 LNRSKRSWMWNQFFLLEEYTGSDYQYVGKLHSDQDRGDGSLKYILSGDGAGDLFIINENT 107
Query: 99 GNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHAT 158
G+I TK LDREEK Y+L AQA++R + RP+EP SEFIIK+ DINDN PIF Y AT
Sbjct: 108 GDIQATKRLDREEKPVYILRAQAINRRTGRPVEPESEFIIKIHDINDNEPIFTKEVYTAT 167
Query: 159 VPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNMDRE 218
VPEMS+VGT V+QVTA DADDP+YGNSAK+VY++L G P+FSV+ +TG+++TA+ NMDRE
Sbjct: 168 VPEMSDVGTFVVQVTATDADDPTYGNSAKVVYSILQGQPYFSVESETGIIKTALLNMDRE 227
Query: 219 TQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLV 278
+E++ VVIQAKDMGG MGGLSG+TTV +TL+DVNDNPP+FPQS YQF E++ PGT +
Sbjct: 228 NREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQSTYQFKTPESSPPGTPI 287
Query: 279 GRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRV 338
GR++A D D+G+NA + YSI DGEG + F + TD + ++G++TV+K LDFE ++ Y+ +V
Sbjct: 288 GRIKASDADVGENAEIEYSITDGEGLDMFDVITDQETQEGIITVKKLLDFEKKKVYTLKV 347
Query: 339 EATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISA 398
EA+N ++P +L GPFKD A+VR+ V+D EPP F++ AY L + E+ T +G ++A
Sbjct: 348 EASNPYVEPRFLYLGPFKDSATVRIVVEDVDEPPVFSKLAYILQIREDAQINTTIGSVTA 407
Query: 399 ADLDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSW 458
D D+ +P++YS+ H+D +R F+I G+I T+ LDRE WHN+TV+ATE+
Sbjct: 408 QDPDAARNPVKYSVDRHTDMDRIFNIDSGNGSIFTSKLLDRETLLWHNITVIATEI---- 463
Query: 459 GPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQLA 518
++ Q+SRV + I+ LD NDNAP+ A
Sbjct: 464 ----------------------------------NNPKQSSRVPLYIKVLDVNDNAPEFA 489
Query: 519 EPYDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQGPLGPDA----NFTVQDNRDGSA 574
E Y+TFVC+ A QLIQ + A+D+D+ + SF L P+A NFT+QDN+D +A
Sbjct: 490 EFYETFVCEKAKADQLIQTLHAVDKDDPYSGHQFSFS--LAPEAASGSNFTIQDNKDNTA 547
Query: 575 SLLLPSRPAPPRH--APYLVPIELWDWGQPALSSTATVTVSVCRCQPDGSVASCWPEAHL 632
+L + RH + YL+P+ + D P SST TVTV VC C G++ SC EA +
Sbjct: 548 G-ILTRKNGYNRHEMSTYLLPVVISDNDYPVQSSTGTVTVRVCACDHHGNMQSCHAEALI 606
Query: 633 SAAGLSTGALLAIITCVGALLALVVLFVALRRQKQEALMVLEEEDVRENIITYDDEGGGE 692
GLSTGAL+AI+ C+ LL VVLF ALRRQ+++ +++ +ED+R+NI++Y+DEGGGE
Sbjct: 607 HPTGLSTGALVAILLCIVILLVTVVLFAALRRQRKKEPLIISKEDIRDNIVSYNDEGGGE 666
Query: 693 EDTEAFDITALQNPDGAAPPAPGPPARRDVLPRARV--SRQPRPPGPADVAQLLALRLRE 750
EDT+AFDI L+NP+ RRD++P A R P DV + RL+E
Sbjct: 667 EDTQAFDIGTLRNPEA----IEDNKLRRDIVPEALFLPRRTPTARDNTDVRDFINQRLKE 722
Query: 751 ADEDPGVPPYDSVQVYGYEGRGSSCGSLSSLGSGSEAGGAPGPAEPLDDWGPLFRTLAEL 810
D DP PPYDS+ Y YEG GS SLSSL S + A + L DWGP F+ LA++
Sbjct: 723 NDTDPTAPPYDSLATYAYEGTGSVADSLSSLESVTT--DADQDYDYLSDWGPRFKKLADM 780
Query: 811 YG 812
YG
Sbjct: 781 YG 782
>gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens]
Length = 788
Score = 738 bits (1905), Expect = 0.0
Identities = 379/785 (48%), Positives = 522/785 (66%), Gaps = 52/785 (6%)
Query: 36 GPALLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVID 95
G L R +R W+WNQFF++EEY G + +GKLHSD D+G+G KY+L+G+GAGT+F+ID
Sbjct: 46 GKILHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGTLFIID 105
Query: 96 EATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPY 155
E TG+IH T+ +DREEKA Y L AQA++R + RP+EP SEF+IK+ DINDN P FP Y
Sbjct: 106 EKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEIY 165
Query: 156 HATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNM 215
A+VPEMS VGTSV+QVTA DADDPSYGNSA+++Y++L G P+FSV+P+TG++RTA+PNM
Sbjct: 166 TASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSILQGQPYFSVEPETGIIRTALPNM 225
Query: 216 DRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPG 275
+RE +E++ VVIQAKDMGG MGGLSG+TTV +TL+DVNDNPP+FPQ+ V+E++ G
Sbjct: 226 NRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLESSPVG 285
Query: 276 TLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYS 335
T +G ++A D D G NA + Y I+DG+G++ F I T+ ++G++TV+KPLD+ES+R Y+
Sbjct: 286 TAIGSVKATDADTGKNAEVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKPLDYESRRLYT 345
Query: 336 FRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQ 395
+VEA NT +DP + GPFKD V+++++D EPP F++++Y V E+ GT++G
Sbjct: 346 LKVEAENTHVDPRFYYLGPFKDTTIVKISIEDVDEPPVFSRSSYLFEVHEDIEVGTIIGT 405
Query: 396 ISAADLDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELG 455
+ A D DS +SPIR+S+ H+D +R F+I G+++T+ PLDRE WHNLTV+A E+
Sbjct: 406 VMARDPDSISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDRELSQWHNLTVIAAEI- 464
Query: 456 WSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAP 515
++ + +RV V ++ LD NDNAP
Sbjct: 465 -------------------------------------NNPKETTRVAVFVRILDVNDNAP 487
Query: 516 QLAEPYDTFVCDSAAPGQLIQVIRALDRDE-VGNSSHVSFQGPLGPDANFTVQDNRDGSA 574
Q A YDTFVC++A PGQLIQ I A+D+D+ +G + P NFTVQDN D +A
Sbjct: 488 QFAVFYDTFVCENARPGQLIQTISAVDKDDPLGGQKFFFSLAAVNP--NFTVQDNEDNTA 545
Query: 575 SLLLPSRPAPPRH--APYLVPIELWDWGQPALSSTATVTVSVCRCQPDGSVASCWPEAHL 632
+L + RH + YL+P+ + D P SST T+T+ VC C G++ SC EA L
Sbjct: 546 R-ILTRKNGFNRHEISTYLLPVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALL 604
Query: 633 SAAGLSTGALLAIITCVGALLALVVLFVALRRQKQEALMVLEEEDVRENIITYDDEGGGE 692
AGLSTGAL+AI+ C+ LL +VVLF AL+RQ+++ ++L +ED+R+NI++Y+DEGGGE
Sbjct: 605 LPAGLSTGALIAILLCIIILLVIVVLFAALKRQRKKEPLILSKEDIRDNIVSYNDEGGGE 664
Query: 693 EDTEAFDITALQNPDGAAPPAPGPPARRDVLPRARV--SRQPRPPGPADVAQLLALRLRE 750
EDT+AFDI L+NP RRD++P R P P DV + RL+E
Sbjct: 665 EDTQAFDIGTLRNPAAIEE----KKLRRDIIPETLFIPRRTPTAPDNTDVRDFINERLKE 720
Query: 751 ADEDPGVPPYDSVQVYGYEGRGSSCGSLSSLGSGSEAGGAPGPAEPLDDWGPLFRTLAEL 810
D DP PPYDS+ Y YEG S SLSSL SG+ G + L +WGP F LAE+
Sbjct: 721 HDLDPTAPPYDSLATYAYEGNDSIAESLSSLESGTTEGDQ--NYDYLREWGPRFNKLAEM 778
Query: 811 YGAKE 815
YG E
Sbjct: 779 YGGGE 783
>gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 733 bits (1893), Expect = 0.0
Identities = 387/780 (49%), Positives = 515/780 (66%), Gaps = 54/780 (6%)
Query: 41 RTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEATGN 100
RT+RSWVWNQFFV+EEY G +P+ +GKLHSDVD+G+G KY+L+GEGA ++F+IDE TG+
Sbjct: 44 RTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGASSIFIIDENTGD 103
Query: 101 IHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVP 160
IH TK LDREE+A Y L AQA+DR +N+P+EP SEF+IK+QDINDN P F GPY A VP
Sbjct: 104 IHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYTAGVP 163
Query: 161 EMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNMDRETQ 220
EMS VGTSV+QVTA DADDP+YGNSA++VY++L G P+FSV+P+TGV++TA+PNMDRE +
Sbjct: 164 EMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQPYFSVEPKTGVIKTALPNMDREAK 223
Query: 221 EEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGR 280
+++L+VIQAKDM G GGLSG+T+VTVTL+DVNDNPP+FP+ YQ++V E+ ++V R
Sbjct: 224 DQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESLPVASVVAR 283
Query: 281 LRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEA 340
++A D D+G NA M Y I+DG+G F IS D + ++G++T++K LDFE++ SY+ R+EA
Sbjct: 284 IKAADADIGANAEMEYKIVDGDGLGIFKISVDKETQEGIITIQKELDFEAKTSYTLRIEA 343
Query: 341 TNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAAD 400
N DP +L GPF D +V++ V+D EPP F+ Y + V E G ++G ++A D
Sbjct: 344 ANKDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQVGNIIGTVAAHD 403
Query: 401 LDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGP 460
DS SP+RYSI ++D ER F+I G I TA LDRE A HN+TVLA E
Sbjct: 404 PDSSNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRETNAIHNITVLAME------- 456
Query: 461 ERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQLAEP 520
+ +Q R VAI LD NDNAP+ A
Sbjct: 457 -------------------------------SQNPSQVGRGYVAITILDINDNAPEFAMD 485
Query: 521 YDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQGPLGPDA----NFTVQDNRDGSASL 576
Y+T VC++A PGQ+IQ I A+D+DE N F L DA NF+++DN+D +AS+
Sbjct: 486 YETTVCENAQPGQVIQKISAVDKDEPSNGHQFYFS--LTTDATNNHNFSLKDNKDNTASI 543
Query: 577 LLPSRP-APPRHAPYLVPIELWDWGQPALSSTATVTVSVCRCQPDGSVASCWPEAHLSAA 635
L + Y +PI + D G P+LSST T+T+ VC C DG +C EA++ A
Sbjct: 544 LTRRNGFRRQEQSVYYLPIFIVDSGSPSLSSTNTLTIRVCDCDADGVAQTCNAEAYVLPA 603
Query: 636 GLSTGALLAIITCVGALLALVVLFVALRRQKQEALMVLEEEDVRENIITYDDEGGGEEDT 695
GLSTGAL+AI+ CV LL L++L V +RR+K+E L+ EE D+RENI+ YDDEGGGEEDT
Sbjct: 604 GLSTGALIAILACVLTLLVLILLIVTMRRRKKEPLIFDEERDIRENIVRYDDEGGGEEDT 663
Query: 696 EAFDITALQNPDGAAPPAPGPPARRDVLPRARVSRQP---RPPGPADVAQLLALRLREAD 752
EAFD+ AL+N + RRDV P + +P P + + RL+EAD
Sbjct: 664 EAFDMAALRNLN----VIRDTKTRRDVTPEIQFLSRPAFKSIPDNVIFREFIWERLKEAD 719
Query: 753 EDPGVPPYDSVQVYGYEGRGSSCGSLSSLGSGSEAGGAPGPAEPLDDWGPLFRTLAELYG 812
DPG PPYDS+Q Y +EG GS SLSSL S S + + L DWGP F+ LA++YG
Sbjct: 720 VDPGAPPYDSLQTYAFEGNGSVAESLSSLDSIS--SNSDQNYDYLSDWGPRFKRLADMYG 777
>gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 733 bits (1893), Expect = 0.0
Identities = 387/780 (49%), Positives = 515/780 (66%), Gaps = 54/780 (6%)
Query: 41 RTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEATGN 100
RT+RSWVWNQFFV+EEY G +P+ +GKLHSDVD+G+G KY+L+GEGA ++F+IDE TG+
Sbjct: 44 RTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGASSIFIIDENTGD 103
Query: 101 IHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVP 160
IH TK LDREE+A Y L AQA+DR +N+P+EP SEF+IK+QDINDN P F GPY A VP
Sbjct: 104 IHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYTAGVP 163
Query: 161 EMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNMDRETQ 220
EMS VGTSV+QVTA DADDP+YGNSA++VY++L G P+FSV+P+TGV++TA+PNMDRE +
Sbjct: 164 EMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQPYFSVEPKTGVIKTALPNMDREAK 223
Query: 221 EEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGR 280
+++L+VIQAKDM G GGLSG+T+VTVTL+DVNDNPP+FP+ YQ++V E+ ++V R
Sbjct: 224 DQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESLPVASVVAR 283
Query: 281 LRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEA 340
++A D D+G NA M Y I+DG+G F IS D + ++G++T++K LDFE++ SY+ R+EA
Sbjct: 284 IKAADADIGANAEMEYKIVDGDGLGIFKISVDKETQEGIITIQKELDFEAKTSYTLRIEA 343
Query: 341 TNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAAD 400
N DP +L GPF D +V++ V+D EPP F+ Y + V E G ++G ++A D
Sbjct: 344 ANKDADPRFLSLGPFSDTTTVKIIVEDVDEPPVFSSPLYPMEVSEATQVGNIIGTVAAHD 403
Query: 401 LDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGP 460
DS SP+RYSI ++D ER F+I G I TA LDRE A HN+TVLA E
Sbjct: 404 PDSSNSPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRETNAIHNITVLAME------- 456
Query: 461 ERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQLAEP 520
+ +Q R VAI LD NDNAP+ A
Sbjct: 457 -------------------------------SQNPSQVGRGYVAITILDINDNAPEFAMD 485
Query: 521 YDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQGPLGPDA----NFTVQDNRDGSASL 576
Y+T VC++A PGQ+IQ I A+D+DE N F L DA NF+++DN+D +AS+
Sbjct: 486 YETTVCENAQPGQVIQKISAVDKDEPSNGHQFYFS--LTTDATNNHNFSLKDNKDNTASI 543
Query: 577 LLPSRP-APPRHAPYLVPIELWDWGQPALSSTATVTVSVCRCQPDGSVASCWPEAHLSAA 635
L + Y +PI + D G P+LSST T+T+ VC C DG +C EA++ A
Sbjct: 544 LTRRNGFRRQEQSVYYLPIFIVDSGSPSLSSTNTLTIRVCDCDADGVAQTCNAEAYVLPA 603
Query: 636 GLSTGALLAIITCVGALLALVVLFVALRRQKQEALMVLEEEDVRENIITYDDEGGGEEDT 695
GLSTGAL+AI+ CV LL L++L V +RR+K+E L+ EE D+RENI+ YDDEGGGEEDT
Sbjct: 604 GLSTGALIAILACVLTLLVLILLIVTMRRRKKEPLIFDEERDIRENIVRYDDEGGGEEDT 663
Query: 696 EAFDITALQNPDGAAPPAPGPPARRDVLPRARVSRQP---RPPGPADVAQLLALRLREAD 752
EAFD+ AL+N + RRDV P + +P P + + RL+EAD
Sbjct: 664 EAFDMAALRNLN----VIRDTKTRRDVTPEIQFLSRPAFKSIPDNVIFREFIWERLKEAD 719
Query: 753 EDPGVPPYDSVQVYGYEGRGSSCGSLSSLGSGSEAGGAPGPAEPLDDWGPLFRTLAELYG 812
DPG PPYDS+Q Y +EG GS SLSSL S S + + L DWGP F+ LA++YG
Sbjct: 720 VDPGAPPYDSLQTYAFEGNGSVAESLSSLDSIS--SNSDQNYDYLSDWGPRFKRLADMYG 777
>gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens]
Length = 789
Score = 726 bits (1873), Expect = 0.0
Identities = 375/793 (47%), Positives = 525/793 (66%), Gaps = 51/793 (6%)
Query: 29 AGSREHPGPALLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGA 88
AG + G L RT+R W+WNQFF++EEY G + +GKLH+D D+G+G KY+LTG+GA
Sbjct: 38 AGLTKDDGKMLRRTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGA 97
Query: 89 GTVFVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPP 148
G++FVIDE TG+IH K LDREEK+ Y+L A+A+DR + R +EP SEFIIK+ DINDN P
Sbjct: 98 GSLFVIDENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEP 157
Query: 149 IFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLPFFSVDPQTGVV 208
F Y A+VPEMS VGTSVIQVTA DADD +YGNSAK+VY++L G P+FSVDP++G++
Sbjct: 158 KFTKDLYTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSILQGQPYFSVDPESGII 217
Query: 209 RTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSV 268
+TA+P+M RE +E++ VVIQAKDMGG MGGLSG+TTV +TL+DVN+NPP+FPQS YQF+
Sbjct: 218 KTALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNS 277
Query: 269 VETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDF 328
E+ GT +GR++A DPD+G+NA M YSI +G+G++ F + TD ++G++TV++ LDF
Sbjct: 278 PESVPLGTHLGRIKANDPDVGENAEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDF 337
Query: 329 ESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKA 388
E+Q Y+ RV+A+NT DP +L GPFKD A V+++V+D EPP FT+ +Y + V E+
Sbjct: 338 ENQMLYTLRVDASNTHPDPRFLHLGPFKDTAVVKISVEDIDEPPVFTKVSYLIEVDEDVK 397
Query: 389 PGTLVGQISAADLDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLT 448
G+++GQ++A D D+ + I+YS+ H+D +R F I E G+I T LDRE+ WHN+T
Sbjct: 398 EGSIIGQVTAYDPDARNNLIKYSVDRHTDMDRIFGIHSENGSIFTLKALDRESSPWHNIT 457
Query: 449 VLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTL 508
V ATE+ ++ Q+S + V I+ L
Sbjct: 458 VTATEI--------------------------------------NNPKQSSHIPVFIRIL 479
Query: 509 DENDNAPQLAEPYDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQGPLGP---DANFT 565
D ND+AP+ A Y+TFVC++A PGQLIQ + +D+D+ H F P+ + NFT
Sbjct: 480 DINDHAPEFAMYYETFVCENAKPGQLIQTVSVMDKDDPPR-GHKFFFEPVPEFTLNPNFT 538
Query: 566 VQDNRDGSASLLL-PSRPAPPRHAPYLVPIELWDWGQPALSSTATVTVSVCRCQPDGSVA 624
+ DN+D +A ++ + + + YL+PI ++D P SST T+T+ VC C G++
Sbjct: 539 IVDNKDNTAGIMTRKDGYSRNKMSTYLLPILIFDNDYPIQSSTGTLTIRVCACDNQGNMQ 598
Query: 625 SCWPEAHLSAAGLSTGALLAIITCVGALLALVVLFVALRRQKQEALMVLEEEDVRENIIT 684
SC EA + +AGLSTGAL+AI+ CV LL LVVLF AL+RQ+++ +++ ++DVR+NI+T
Sbjct: 599 SCTAEALILSAGLSTGALVAILLCVLILLILVVLFAALKRQRKKEPLIISKDDVRDNIVT 658
Query: 685 YDDEGGGEEDTEAFDITALQNPDGAAPPAPGPPARRDVLPRA--RVSRQPRPPGPADVAQ 742
Y+DEGGGEEDT+AFDI L+NP+ RRDV+P ++ R DV
Sbjct: 659 YNDEGGGEEDTQAFDIGTLRNPEA----REDSKLRRDVMPETIFQIRRTVPLWENIDVQD 714
Query: 743 LLALRLREADEDPGVPPYDSVQVYGYEGRGSSCGSLSSLGSGSEAGGAPGPAEPLDDWGP 802
+ RL+E D DP PPYDS+ Y YEG S SLSSL S + L DWGP
Sbjct: 715 FIHRRLKENDADPSAPPYDSLATYAYEGNDSIADSLSSL--ESLTADCNQDYDYLSDWGP 772
Query: 803 LFRTLAELYGAKE 815
F+ LA++YG +
Sbjct: 773 RFKKLADMYGGDD 785
>gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens]
Length = 794
Score = 709 bits (1831), Expect = 0.0
Identities = 378/797 (47%), Positives = 516/797 (64%), Gaps = 57/797 (7%)
Query: 30 GSREHPGPALLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAG 89
G R H R +R WVWNQFFV+EEY G EP +GKLHSD+D+GEG KY L+G+GAG
Sbjct: 44 GQRSH----FQRVKRGWVWNQFFVLEEYVGSEPQYVGKLHSDLDKGEGTVKYTLSGDGAG 99
Query: 90 TVFVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPI 149
TVF IDE TG+IH +SLDREEK Y L AQAVD + +PLEP SEFIIKVQDINDN P
Sbjct: 100 TVFTIDETTGDIHAIRSLDREEKPFYTLRAQAVDIETRKPLEPESEFIIKVQDINDNEPK 159
Query: 150 FPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLPFFSVDPQTGVVR 209
F GPY ATVPEMS VG V+QV A DADDP+YGNSA++VY++L G P+FS+DP+TGV+R
Sbjct: 160 FLDGPYVATVPEMSPVGAYVLQVKATDADDPTYGNSARVVYSILQGQPYFSIDPKTGVIR 219
Query: 210 TAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVV 269
TA+PNMDRE +E++ V+IQAKDMGG +GGL+G+T V +TL+DVNDNPP+FP+S++ V
Sbjct: 220 TALPNMDREVKEQYQVLIQAKDMGGQLGGLAGTTIVNITLTDVNDNPPRFPKSIFHLKVP 279
Query: 270 ETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFE 329
E++ G+ +GR+RA DPD G NA + Y+I+ G+G F I TD ++G++ ++KPLDFE
Sbjct: 280 ESSPIGSAIGRIRAVDPDFGQNAEIEYNIVPGDGGNLFDIVTDEDTQEGVIKLKKPLDFE 339
Query: 330 SQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKAP 389
++++Y+F+VEA+N +D + GPFKD A+V+++V D EPP F++ Y + V E+
Sbjct: 340 TKKAYTFKVEASNLHLDHRFHSAGPFKDTATVKISVLDVDEPPVFSKPLYTMEVYEDTPV 399
Query: 390 GTLVGQISAADLDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTV 449
GT++G ++A DLD +S +RY I SD + F+I EGTI T LDRE+ A +N ++
Sbjct: 400 GTIIGAVTAQDLDVGSSAVRYFIDWKSDGDSYFTIDGNEGTIATNELLDRESTAQYNFSI 459
Query: 450 LATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTLD 509
+A+++ PLL S+V + I LD
Sbjct: 460 IASKVS---------NPLL-----------------------------TSKVNILINVLD 481
Query: 510 ENDNAPQLAEPYDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQGPLGPDA----NFT 565
N+ P+++ PY+T VC++A PGQ+IQ++ A DRD SF+ L P+A NFT
Sbjct: 482 VNEFPPEISVPYETAVCENAKPGQIIQIVSAADRDLSPAGQQFSFR--LSPEAAIKPNFT 539
Query: 566 VQDNRDGSASLLLPSRPAPPRHAP-YLVPIELWDWGQPALSSTATVTVSVCRCQPDGSVA 624
V+D R+ +A + R Y +P+ + D P SST T+T+ VCRC DG++
Sbjct: 540 VRDFRNNTAGIETRRNGYSRRQQELYFLPVVIEDSSYPVQSSTNTMTIRVCRCDSDGTIL 599
Query: 625 SCWPEAHLSAAGLSTGALLAIITCVGALLALVVLFVALRRQKQEALMVLEEEDVRENIIT 684
SC EA GLSTGAL+AI+ C+ LLA+VVL+VALRRQK++ ++ +ED+R+N+I
Sbjct: 600 SCNVEAIFLPVGLSTGALIAILLCIVILLAIVVLYVALRRQKKKDTLMTSKEDIRDNVIH 659
Query: 685 YDDEGGGEEDTEAFDITALQNPDGAAPPAPGPPARRDVLPRARVSRQPRPP--GPADVAQ 742
YDDEGGGEEDT+AFDI AL+NP RRD+ P + + RPP D+
Sbjct: 660 YDDEGGGEEDTQAFDIGALRNP----KVIEENKIRRDIKPDSLCLPRQRPPMEDNTDIRD 715
Query: 743 LLALRLREADEDPGVPPYDSVQVYGYEGRGSSCGSLSSLGSGSEAGGAPGPAEPLDDWGP 802
+ RL+E D DP PPYDS+ Y YEG GS SLSS+ S + A + L DWGP
Sbjct: 716 FIHQRLQENDVDPTAPPYDSLATYAYEGSGSVAESLSSIDSLTTE--ADQDYDYLTDWGP 773
Query: 803 LFRTLAELYGAKEPPAP 819
F+ LA+++G +E P
Sbjct: 774 RFKVLADMFGEEESYNP 790
>gi|16753221 cadherin 22 precursor [Homo sapiens]
Length = 828
Score = 655 bits (1691), Expect = 0.0
Identities = 371/828 (44%), Positives = 499/828 (60%), Gaps = 78/828 (9%)
Query: 18 MGRLAA---PARAWAGSREHPGPALLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDR 74
+GRL A P+ + G+R+ R +R WVWNQFFV+EEY G EP+ +GK+HSD D
Sbjct: 33 LGRLWAAGTPSPSAPGARQDGALGAGRVKRGWVWNQFFVVEEYTGTEPLYVGKIHSDSDE 92
Query: 75 GEGRTKYLLTGEGAGTVFVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPS 134
G+G KY ++GEGAGT+F+IDE TG+IH + LDRE+K Y L AQA DRA+NR LEP S
Sbjct: 93 GDGAIKYTISGEGAGTIFLIDELTGDIHAMERLDREQKTFYTLRAQARDRATNRLLEPES 152
Query: 135 EFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLD 194
EFIIKVQDIND+ P F GPY +V E+S GTSV+QV A DADDP+YG+SA+LVY+VLD
Sbjct: 153 EFIIKVQDINDSEPRFLHGPYIGSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSVLD 212
Query: 195 GLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVND 254
G F+VDP+TGV+RTA+P++DRE+QE + VVIQA DM G +GGLSGSTTVT+ ++DVND
Sbjct: 213 GEHHFTVDPKTGVIRTAVPDLDRESQERYEVVIQATDMAGQLGGLSGSTTVTIVVTDVND 272
Query: 255 NPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILD--GEGSEAFSISTD 312
NPP+FPQ +YQFS+ E+A GT VGR++A+D D+G+N M Y + D G + F ++TD
Sbjct: 273 NPPRFPQKMYQFSIQESAPIGTAVGRVKAEDSDVGENTDMTYHLKDESSSGGDVFKVTTD 332
Query: 313 LQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPP 372
++ ++ V+K LDFESQ ++ +EA N +DP + G F+D A VRVAV D EPP
Sbjct: 333 SDTQEAIIVVQKRLDFESQPVHTVILEALNKFVDPRFADLGTFRDQAIVRVAVTDVDEPP 392
Query: 373 AFTQAAYHLTVPENKAPGTLVGQISAADLDSPASPIRYSILPHSDPERCFSIQPEEGTIH 432
F + L V E+ G+LVG ++A D D+ P+RY+I SD ++ F I + G I
Sbjct: 393 EFRPPSGLLEVQEDAQVGSLVGVVTARDPDAANRPVRYAIDRESDLDQIFDIDADTGAIV 452
Query: 433 TAAPLDREARAWHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQ 492
T LDRE WHN+TVLA E
Sbjct: 453 TGKGLDRETAGWHNITVLAME--------------------------------------A 474
Query: 493 DSSAQASRVQVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRALDRDEVGNSSHV 552
D+ AQ SR + I+ LD NDN P+LA PY+ VC+ A PGQLIQ I +DRDE
Sbjct: 475 DNHAQLSRASLRIRILDVNDNPPELATPYEAAVCEDAKPGQLIQTISVVDRDEPQGGHRF 534
Query: 553 SFQGPLGPDA----NFTVQDNRDGSASLLLPSRPAPPRHAP-YLVPIELWDWGQPALSST 607
F+ L P+A +F++ D +D +A++ + + +PI + D G P LSST
Sbjct: 535 YFR--LVPEAPSNPHFSLLDIQDNTAAVHTQHVGFNRQEQDVFFLPILVVDSGPPTLSST 592
Query: 608 ATVTVSVCRCQPDGSVASCWPEAHLSAAGLSTGALLAIITCVGALLALVVLFVALRRQKQ 667
T+T+ +C C G++ SC A + AA LS GAL+A++ CV L+ LV+L + LRR +
Sbjct: 593 GTLTIRICGCDSSGTIQSCNTTAFVMAASLSPGALIALLVCVLILVVLVLLILTLRRHHK 652
Query: 668 EALMVLEEEDVRENIITYDDEGGGEEDTEAFDITALQN--------------------PD 707
L E+ED+R+N+I Y+DEGGGE+DTEA+D++AL++
Sbjct: 653 SHLSSDEDEDMRDNVIKYNDEGGGEQDTEAYDMSALRSLYDFGELKGGDGGGSAGGGAGG 712
Query: 708 GAAPPAPGPPARRDVLPRARVSRQPRPPGP----ADVAQLLALRLREADEDPGVPPYDSV 763
G+ A PP LP R S PP P + ++ ++ AD D VPPYD+
Sbjct: 713 GSGGGAGSPPQAH--LPSERHSLPQGPPSPEPDFSVFRDFISRKVALADGDLSVPPYDAF 770
Query: 764 QVYGYEGRGSSCGSLSSLGSGSEAGGAPGPAEPLDDWGPLFRTLAELY 811
Q Y +EG S SLSSL SGS G+ L WGP FR LA LY
Sbjct: 771 QTYAFEGADSPAASLSSLHSGS--SGSEQDFAYLSSWGPRFRPLAALY 816
>gi|12656655 cadherin 19, type 2 preproprotein [Homo sapiens]
Length = 772
Score = 538 bits (1385), Expect = e-152
Identities = 320/813 (39%), Positives = 463/813 (56%), Gaps = 55/813 (6%)
Query: 4 LVRLLLAWLGGWGCMGRLAAPARAWAGSREHPGPALLRTRRSWVWNQFFVIEEYAGPEPV 63
L+R +L W C+G A + + P + LR +R WVWNQFFV EE
Sbjct: 6 LLRFMLGIPLLWPCLG---ATENSQTKKVKQPVRSHLRVKRGWVWNQFFVPEEM-NTTSH 61
Query: 64 LIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEATGNIHVTKSLDREEKAQYVLLAQAVD 123
IG+L SD+D G +Y L G GAG+ F+IDE TG+I+ + LDREE++ Y+L AQ +D
Sbjct: 62 HIGQLRSDLDNGNNSFQYKLLGAGAGSTFIIDERTGDIYAIQKLDREERSLYILRAQVID 121
Query: 124 RASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYG 183
A+ R +EP SEF+IKV DINDN P F PY A VPEMS GT VIQVTA DADDPS G
Sbjct: 122 IATGRAVEPESEFVIKVSDINDNEPKFLDEPYEAIVPEMSPEGTLVIQVTASDADDPSSG 181
Query: 184 NSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGST 243
N+A+L+Y++L G P+FSV+P TGV+R + MDRE Q+E+ V+IQAKDM G G LSG+T
Sbjct: 182 NNARLLYSLLQGQPYFSVEPTTGVIRIS-SKMDRELQDEYWVIIQAKDMIGQPGALSGTT 240
Query: 244 TVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEG 303
+V + LSDVNDN P F +SLY+ +V E+A GT +G + A D D+G+NA M YSI + +
Sbjct: 241 SVLIKLSDVNDNKPIFKESLYRLTVSESAPTGTSIGTIMAYDNDIGENAEMDYSI-EEDD 299
Query: 304 SEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRV 363
S+ F I T+ + ++G++ ++K +DFE Q Y R + N + ++ +++
Sbjct: 300 SQTFDIITNHETQEGIVILKKKVDFEHQNHYGIRAKVKNHHVPEQLMKYHTEASTTFIKI 359
Query: 364 AVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAADLDSPASPIRYSILPHSDPERCFS 423
V+D EPP F Y V E G+ VG +SA D D+ SPIRYSI + F+
Sbjct: 360 QVEDVDEPPLFLLPYYVFEVFEETPQGSFVGVVSATDPDNRKSPIRYSI----TRSKVFN 415
Query: 424 IQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSP 483
I + GTI T+ LDRE AW+NL++ ATE
Sbjct: 416 IN-DNGTITTSNSLDREISAWYNLSITATE------------------------------ 444
Query: 484 VGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRALDR 543
+ + Q S + + +Q L+ ND+AP+ ++ Y+T+VC++A GQ+IQ I A+DR
Sbjct: 445 --------KYNIEQISSIPLYVQVLNINDHAPEFSQYYETYVCENAGSGQVIQTISAVDR 496
Query: 544 DEVGNSSHVSFQGPLGP--DANFTVQDNRDGSASLLLPSRPAPPRHAP-YLVPIELWDWG 600
DE H F + +++FT+ DN+D +A +L + P + + I + D G
Sbjct: 497 DESIEEHHFYFNLSVEDTNNSSFTIIDNQDNTAVILTNRTGFNLQEEPVFYISILIADNG 556
Query: 601 QPALSSTATVTVSVCRCQPDGSVASCWPEAHLSAAGLSTGALLAIITCVGALLALVVLFV 660
P+L+ST T+T+ VC C GS +C + + + G T ++AI+ C+ + + L +
Sbjct: 557 IPSLTSTNTLTIHVCDCGDSGSTQTCQYQELVLSMGFKTEVIIAILICIMIIFGFIFLTL 616
Query: 661 ALRRQKQEALMVLEEEDVRENIITYDDEGGGEEDTEAFDITALQNPDGAAPPAPGPPARR 720
L++++++ L + ED RENI YDDEGGGEEDTEAFDI L++
Sbjct: 617 GLKQRRKQILFPEKSEDFRENIFQYDDEGGGEEDTEAFDIAELRSSTIMRERKTRKTTSA 676
Query: 721 DVLPRARVSRQPRPPGPADVAQLLALRLREADEDPGVPPYDSVQVYGYEGRGSSCGSLSS 780
++ R S Q P A + + +L EA+ DP PP+DS+Q Y +EG GS GSLSS
Sbjct: 677 EIRSLYRQSLQVGPDS-AIFRKFILEKLEEANTDPCAPPFDSLQTYAFEGTGSLAGSLSS 735
Query: 781 LGSGSEAGGAPGPAEPLDDWGPLFRTLAELYGA 813
L S + L++ GP F+ LA ++G+
Sbjct: 736 LESA--VSDQDESYDYLNELGPRFKRLACMFGS 766
>gi|166362713 cadherin 5, type 2 preproprotein [Homo sapiens]
Length = 784
Score = 494 bits (1272), Expect = e-139
Identities = 312/823 (37%), Positives = 449/823 (54%), Gaps = 64/823 (7%)
Query: 6 RLLLAWLGGWGCMGRLAAPARAWAGSREHPG------PALLRTRRSWVWNQFFVIEEYAG 59
RL++ C+G LA A A AG+ P R +R W+WNQ + EE
Sbjct: 3 RLMMLLATSGACLGLLAVAAVAAAGANPAQRDTHSLLPTHRRQKRDWIWNQMHIDEEKNT 62
Query: 60 PEPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEATGNIHVTKSLDREEKAQYVLLA 119
P +GK+ S V R KYLL GE G VF +D TG++ + LDRE ++Y L A
Sbjct: 63 SLPHHVGKIKSSVSRKNA--KYLLKGEYVGKVFRVDAETGDVFAIERLDRENISEYHLTA 120
Query: 120 QAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADD 179
VD+ + LE PS F IKV D+NDN P+F ++A+VPE S VGTSVI VTA DADD
Sbjct: 121 VIVDKDTGENLETPSSFTIKVHDVNDNWPVFTHRLFNASVPESSAVGTSVISVTAVDADD 180
Query: 180 PSYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGL 239
P+ G+ A ++Y +L G +F++D +G + T ++DRE Q + +V++A+D G + G
Sbjct: 181 PTVGDHASVMYQILKGKEYFAID-NSGRIITITKSLDREKQARYEIVVEARDAQG-LRGD 238
Query: 240 SGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSIL 299
SG+ TV VTL D+NDN P F Q+ Y F V E GT VG L +DPD N + YSIL
Sbjct: 239 SGTATVLVTLQDINDNFPFFTQTKYTFVVPEDTRVGTSVGSLFVEDPDEPQNRMTKYSIL 298
Query: 300 DGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVA 359
G+ +AF+I T+ +G++ KPLD+E + YSF VEAT+ ID Y+ P + A
Sbjct: 299 RGDYQDAFTIETNPAHNEGIIKPMKPLDYEYIQQYSFIVEATDPTIDLRYM-SPPAGNRA 357
Query: 360 SVRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAADLDSPASPIRYSILPHSDPE 419
V + + D EPP F Q YH + EN+ L+G + A D D+ I YSI SD
Sbjct: 358 QVIINITDVDEPPIFQQPFYHFQLKENQKK-PLIGTVLAMDPDAARHSIGYSIRRTSDKG 416
Query: 420 RCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPP 479
+ F + ++G I+ LDRE W+NLTV A EL
Sbjct: 417 QFFRV-TKKGDIYNEKELDREVYPWYNLTVEAKEL------------------------- 450
Query: 480 QRSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIR 539
+ G P + + S VQV I+ LDENDNAP+ A+PY VC++A GQL+ I
Sbjct: 451 ------DSTGTP---TGKESIVQVHIEVLDENDNAPEFAKPYQPKVCENAVHGQLVLQIS 501
Query: 540 ALDRDEVGNSSHVSFQGPLGPDANFTVQDNRDGSASLLLPSRPAPPRHAP-YLVPIELWD 598
A+D+D +V F+ L + NFT+ DN D +A++ + H + +P+ + D
Sbjct: 502 AIDKDI--TPRNVKFKFILNTENNFTLTDNHDNTANITVKYGQFDREHTKVHFLPVVISD 559
Query: 599 WGQPALSSTATVTVSVCRCQPDGSVASCWPEAHLSAAGLSTGALLAIITCVGALLALVVL 658
G P+ + T+T+TV+VC+C G C E + G+S A++AI+ C+ + + +L
Sbjct: 560 NGMPSRTGTSTLTVAVCKCNEQGEFTFC--EDMAAQVGVSIQAVVAILLCILTITVITLL 617
Query: 659 -FVALRRQKQEALMVLEEEDVRENIITYDDEGGGEEDTEAFDITALQN--PDGAAPPAPG 715
F+ R +KQ ++ E ++TYD+EGGGE DT ++D++ L + GA PP P
Sbjct: 618 IFLRRRLRKQARAHGKSVPEIHEQLVTYDEEGGGEMDTTSYDVSVLNSVRRGGAKPPRPA 677
Query: 716 PPARRDVLPRARVSRQPRPP-----GPADVAQLLALRLREADEDPGVPPYDSVQVYGYEG 770
AR + A+V + PR GP ++A ++ ++ EAD D PPYD++ +YGYEG
Sbjct: 678 LDARPSLY--AQVQKPPRHAPGAHGGPGEMAAMIEVKKDEADHDGDGPPYDTLHIYGYEG 735
Query: 771 RGSSCGSLSSLGSGSEAGGAPGPAEPLDDWGPLFRTLAELYGA 813
S SLSSLG+ S + L+DWGP F+ LAELYG+
Sbjct: 736 SESIAESLSSLGTDSSDSDV--DYDFLNDWGPRFKMLAELYGS 776
>gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens]
Length = 916
Score = 367 bits (942), Expect = e-101
Identities = 288/807 (35%), Positives = 401/807 (49%), Gaps = 86/807 (10%)
Query: 39 LLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGT----VFVI 94
L R +R WV V E GP P + ++ SD D + +Y +TG GA VF I
Sbjct: 164 LRRRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDN-DIPIRYSITGVGADQPPMEVFSI 222
Query: 95 DEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGP 154
D +G ++VT+ +DREE A Y L A AVD N+ +E P + I V D+NDN P F
Sbjct: 223 DSMSGRMYVTRPMDREEHASYHLRAHAVDMNGNK-VENPIDLYIYVIDMNDNRPEFINQV 281
Query: 155 YHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLP------FFSVDPQTGVV 208
Y+ +V E S GT V+ VTA+DADD + N + Y ++ P F+++ +TG +
Sbjct: 282 YNGSVDEGSKPGTYVMTVTANDADDSTTAN-GMVRYRIVTQTPQSPSQNMFTINSETGDI 340
Query: 209 RTAIPNMDRETQEEFLVVIQAKDMGGHMG-GLSGSTTVTVTLSDVNDNPPKFPQSLYQFS 267
T +DRE +++ V++QA DM G++ GLS + T +T++DVNDNPP+F S +
Sbjct: 341 VTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGE 400
Query: 268 VVETAGPGTLVGRLRAQDPDL--GDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKP 325
V E T+V L D D N Y I+ G+ S FS+ TD +G++TV K
Sbjct: 401 VPENR-VETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKA 459
Query: 326 LDFESQRSYSFRVEATNTLIDPAYLRRG---PFKDVASVRVAVQDAPEPPAFTQAAYHLT 382
+D+E R++ V +N A L G F+ A V +++ D E P F +
Sbjct: 460 VDYELNRAFMLTVMVSN----QAPLASGIQMSFQSTAGVTISIMDINEAPYFPSNHKLIR 515
Query: 383 VPENKAPGTLVGQISAADLDS-PASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREA 441
+ E PGT++ SA D D +RYS L SDP I G I TAA LDRE+
Sbjct: 516 LEEGVPPGTVLTTFSAVDPDRFMQQAVRYSKL--SDPASWLHINATNGQITTAAVLDRES 573
Query: 442 RAWHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRV 501
N AT L A P S G Q
Sbjct: 574 LYTKNNVYEATFL----------------------AADNGIPPASGTGTLQ--------- 602
Query: 502 QVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQGPLGPD 561
I +D NDNAP+L P + +C+ P I A D D N F+ P P
Sbjct: 603 ---IYLIDINDNAPELL-PKEAQICEK--PNLNAINITAADADVDPNIGPYVFELPFVPA 656
Query: 562 A---NFTVQDNRDGSASLLLPSRPAPPRHAPYLVPIELWDWGQPALSSTATVTVSVCRCQ 618
A N+T+ A L L R Y VPI + D G P LS+T+ + V VC C
Sbjct: 657 AVRKNWTITRLNGDYAQLSL--RILYLEAGMYDVPIIVTDSGNPPLSNTSIIKVKVCPCD 714
Query: 619 PDGSVASCWPEAHLSAAGLSTGALLAIITCVGALLALVVLFV--ALRRQKQ---EALMVL 673
+G C ++AAGL TGA++AI+ C+ LL +V+LFV RR+K+ + L++
Sbjct: 715 DNG---DCTTIGAVAAAGLGTGAIVAILICILILLTMVLLFVMWMKRREKERHTKQLLID 771
Query: 674 EEEDVRENIITYDDEGGGEEDTEAFDITALQNPDGAA-PPAPGPPARR-DVLPRARVSRQ 731
E+DVR+NI+ YD+EGGGEED + +D++ LQ P+ P+ P RR D P +
Sbjct: 772 PEDDVRDNILKYDEEGGGEEDQD-YDLSQLQQPEAMGHVPSKAPGVRRVDERPVGAEPQY 830
Query: 732 P-RP--PGPADVAQLLALRLREADEDPGVPPYDSVQVYGYEGRGSSCGSLSSLGSGSEAG 788
P RP P P D+ + LR AD DP PPYDS+ V+ YEG GS+ GS+SSL S S
Sbjct: 831 PIRPMVPHPGDIGDFINEGLRAADNDPTAPPYDSLLVFDYEGSGSTAGSVSSLNSSS--- 887
Query: 789 GAPGPAEPLDDWGPLFRTLAELYGAKE 815
+ L+DWGP F+ LA++YG E
Sbjct: 888 SGDQDYDYLNDWGPRFKKLADMYGGGE 914
>gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens]
Length = 906
Score = 364 bits (934), Expect = e-100
Identities = 283/801 (35%), Positives = 395/801 (49%), Gaps = 79/801 (9%)
Query: 39 LLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGT----VFVI 94
L R +R WV + E GP P + ++ SD D+ +Y +TG GA +F+I
Sbjct: 154 LQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDKNLS-LRYSVTGPGADQPPTGIFII 212
Query: 95 DEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGP 154
+ +G + VTK LDRE+ A++ L A AVD N+ +E P + +I V D+NDN P F
Sbjct: 213 NPISGQLSVTKPLDREQIARFHLRAHAVDINGNQ-VENPIDIVINVIDMNDNRPEFLHQV 271
Query: 155 YHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLP------FFSVDPQTGVV 208
++ TVPE S GT V+ VTA DADDP+ N L Y ++ P F+++ +TG +
Sbjct: 272 WNGTVPEGSKPGTYVMTVTAIDADDPNALN-GMLRYRIVSQAPSTPSPNMFTINNETGDI 330
Query: 209 RTAIPNMDRETQEEFLVVIQAKDMGGH-MGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFS 267
T +DRE +++ ++IQA DM G+ GLS + T +T++DVNDNPP+F +
Sbjct: 331 ITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGE 390
Query: 268 VVETAGPGTLVGRLRAQDPDLGDNAL--MAYSILDGEGSEAFSISTDLQGRDGLLTVRKP 325
V E +V L D D Y I G+ + F+I TD DGL+TV KP
Sbjct: 391 VPENR-VDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKP 449
Query: 326 LDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPE 385
+DFE+ R + V A N + ++ P + A+V V V D E P F + E
Sbjct: 450 IDFETNRMFVLTVAAENQVPLAKGIQHPP-QSTATVSVTVIDVNENPYFAPNPKIIRQEE 508
Query: 386 NKAPGTLVGQISAADLDS-PASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAW 444
GT++ +A D D IRY+ L SDP I P G I T A LDRE+
Sbjct: 509 GLHAGTMLTTFTAQDPDRYMQQNIRYTKL--SDPANWLKIDPVNGQITTIAVLDRESPNV 566
Query: 445 HNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVA 504
N AT L S GIP S +
Sbjct: 567 KNNIYNATFL------------------------------ASDNGIPPMSGTGT----LQ 592
Query: 505 IQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQGPLGP---D 561
I LD NDNAPQ+ P + C++ P + I ALD D N+ +F PL P
Sbjct: 593 IYLLDINDNAPQVL-PQEAETCETPDPNSI--NITALDYDIDPNAGPFAFDLPLSPVTIK 649
Query: 562 ANFTVQDNRDGSASLLLPSRPAPPRHAPYLVPIELWDWGQPALSSTATVTVSVCRCQPDG 621
N+T+ A L L + Y VPI + D G P S+ + + V VC+C +G
Sbjct: 650 RNWTITRLNGDFAQLNLKIKFL--EAGIYEVPIIITDSGNPPKSNISILRVKVCQCDSNG 707
Query: 622 SVASCWPEAHLSAAGLSTGALLAIITCVGALLALVVLFVA--LRRQKQ---EALMVLEEE 676
C + AGL TGA++AI+ C+ LL LV++FV RR K+ + L++ E+
Sbjct: 708 ---DCTDVDRIVGAGLGTGAIIAILLCIIILLILVLMFVVWMKRRDKERQAKQLLIDPED 764
Query: 677 DVRENIITYDDEGGGEEDTEAFDITALQNPDGAAPPAPGPPA--RRDVLPRARVSRQP-- 732
DVR+NI+ YD+EGGGEED + +D++ LQ PD P A P R D P + P
Sbjct: 765 DVRDNILKYDEEGGGEEDQD-YDLSQLQQPDTVEPDAIKPVGIRRMDERPIHAEPQYPVR 823
Query: 733 -RPPGPADVAQLLALRLREADEDPGVPPYDSVQVYGYEGRGSSCGSLSSLGSGSEAGGAP 791
P P D+ + L+ AD DP PPYDS+ V+ YEG GS+ GSLSSL S S G
Sbjct: 824 SAAPHPGDIGDFINEGLKAADNDPTAPPYDSLLVFDYEGSGSTAGSLSSLNSSS--SGGE 881
Query: 792 GPAEPLDDWGPLFRTLAELYG 812
+ L+DWGP F+ LA++YG
Sbjct: 882 QDYDYLNDWGPRFKKLADMYG 902
>gi|4826669 cadherin 15 preproprotein [Homo sapiens]
Length = 814
Score = 331 bits (849), Expect = 1e-90
Identities = 266/801 (33%), Positives = 388/801 (48%), Gaps = 82/801 (10%)
Query: 37 PALLRTRRSWVWNQFFVIEEYAG-PEPVLIGKLHSDVDRGEGRTKYLLTGEGAGT----V 91
PAL R RR+WV V E + P P++ ++ SD + G Y + G G V
Sbjct: 38 PALSRVRRAWVIPPISVSENHKRLPYPLV--QIKSDKQQ-LGSVIYSIQGPGVDEEPRGV 94
Query: 92 FVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFP 151
F ID+ TG + + LDRE+ ++ L A A+D + LE P++ I V D NDN P F
Sbjct: 95 FSIDKFTGKVFLNAMLDREKTDRFRLRAFALDLGGST-LEDPTDLEIVVVDQNDNRPAFL 153
Query: 152 LGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLP-FFSVDPQTGVVRT 210
+ V E + GT V + A DADDP N+A + G P FS+D TG +RT
Sbjct: 154 QEAFTGRVLEGAVPGTYVTRAEATDADDPETDNAALRFSILQQGSPELFSIDELTGEIRT 213
Query: 211 AIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVE 270
+DRE + + +Q DM G GL+ + + +TL D+NDN P+F + + +E
Sbjct: 214 VQVGLDREVVAVYNLTLQVADMSGD--GLTATASAIITLDDINDNAPEFTRDEFFMEAIE 271
Query: 271 TAGPGTLVGRLRAQDPDL--GDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDF 328
G VGRL +D DL N + ++IL+G+ F+I TD + +G+L++ K LD+
Sbjct: 272 AVS-GVDVGRLEVEDRDLPGSPNWVARFTILEGDPDGQFTIRTDPKTNEGVLSIVKALDY 330
Query: 329 ESQRSYSFRVEATNTL-IDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENK 387
ES Y +V N + A LR + A VRV VQD EPP F + ++ E
Sbjct: 331 ESCEHYELKVSVQNEAPLQAAALRAE--RGQAKVRVHVQDTNEPPVFQENPLRTSLAEGA 388
Query: 388 APGTLVGQISAADLDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNL 447
PGTLV SA D D+ R S DPE + G I T L
Sbjct: 389 PPGTLVATFSARDPDTEQLQ-RLSYSKDYDPEDWLQVDAATGRIQTQHVL---------- 437
Query: 448 TVLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQ--ASRVQVAI 505
+PA+P + A+ + QD ++Q + ++I
Sbjct: 438 --------------------------SPASPFLKGGWYRAIVLAQDDASQPRTATGTLSI 471
Query: 506 QTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQ-GPLGPD--A 562
+ L+ ND+AP LA P +C G + ++ A D D + + FQ P P+
Sbjct: 472 EILEVNDHAPVLAPPPPGSLCSEPHQGPGL-LLGATDEDLPPHGAPFHFQLSPRLPELGR 530
Query: 563 NFTVQDNRDGSASLLLPSRPAPPRHAPYLVPIELWDWGQPALSSTATVTVSVCRCQPDGS 622
N+++ + S + L P P + + + L D GQP + V+VCRC DG
Sbjct: 531 NWSL-SQVNVSHARLRPRHQVP--EGLHRLSLLLRDSGQPPQQREQPLNVTVCRCGKDG- 586
Query: 623 VASCWPEAHLSAA---GLSTGALLAIITCVGALLALVVLFVALR-----RQKQEALMVLE 674
C P A A GLS GAL+ I+ LL ++VL VALR + + + L+
Sbjct: 587 --VCLPGAAALLAGGTGLSLGALV-IVLASALLLLVLVLLVALRARFWKQSRGKGLLHGP 643
Query: 675 EEDVRENIITYDDEGGGEEDTEAFDITALQNPDGAAPPAPGPPARRDVLPRARVSRQP-- 732
++D+R+N++ YD++GGGEED +A+DI+ L++P + P PP RRD P+ R+ QP
Sbjct: 644 QDDLRDNVLNYDEQGGGEEDQDAYDISQLRHPTALSLPLGPPPLRRDA-PQGRLHPQPPR 702
Query: 733 -RPPGPADVAQLLALRLREADEDPGVPPYDSVQVYGYEGRGSSCGSLSSLGSGSEAGGAP 791
P P D+A + L AD DP VPPYD+ +Y YEG GS G+LSS+ S G
Sbjct: 703 VLPTSPLDIADFINDGLEAADSDPSVPPYDTALIYDYEGDGSVAGTLSSILSSQ--GDED 760
Query: 792 GPAEPLDDWGPLFRTLAELYG 812
+ L DWGP F LA++YG
Sbjct: 761 QDYDYLRDWGPRFARLADMYG 781
>gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens]
Length = 882
Score = 319 bits (817), Expect = 7e-87
Identities = 259/801 (32%), Positives = 378/801 (47%), Gaps = 89/801 (11%)
Query: 37 PALLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGT----VF 92
P L R +R WV E GP P + ++ S+ D+ EG+ Y +TG+GA T VF
Sbjct: 147 PGLRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDK-EGKVFYSITGQGADTPPVGVF 205
Query: 93 VIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPL 152
+I+ TG + VT+ LDRE A Y L + AV N +E P E +I V D NDN P F
Sbjct: 206 IIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNA-VEDPMEILITVTDQNDNKPEFTQ 264
Query: 153 GPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLP------FFSVDPQTG 206
+ +V E + GTSV++VTA DADD +A + YT+L P F+++ TG
Sbjct: 265 EVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTG 324
Query: 207 VVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQF 266
V+ +DRE+ + +V+QA D+ G GLS + T +T++D NDNPP F + Y+
Sbjct: 325 VISVVTTGLDRESFPTYTLVVQAADLQGE--GLSTTATAVITVTDTNDNPPIFNPTTYKG 382
Query: 267 SVVETAGPGTLVGRLRAQDPDLGDNAL--MAYSILDGEGSEAFSISTDLQGRDGLLTVRK 324
V E ++ L+ D D + Y+IL+ +G + F ++T+ DG+L K
Sbjct: 383 QVPENEA-NVVITTLKVTDADAPNTPAWEAVYTILNDDGGQ-FVVTTNPVNNDGILKTAK 440
Query: 325 PLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVP 384
LDFE+++ Y V TN + L A+V V V D E P F + V
Sbjct: 441 GLDFEAKQQYILHVAVTNVVPFEVSLT----TSTATVTVDVLDVNEAPIFVPPEKRVEVS 496
Query: 385 ENKAPGTLVGQISAADLDS-PASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDRE--- 440
E+ G + +A + D+ I Y I D I P+ G I T A LDRE
Sbjct: 497 EDFGVGQEITSYTAQEPDTFMEQKITYRI--WRDTANWLEINPDTGAISTRAELDREDFE 554
Query: 441 --ARAWHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQA 498
+ + ++AT+ G SPV + G
Sbjct: 555 HVKNSTYTALIIATDNG--------------------------SPVATGTG--------- 579
Query: 499 SRVQVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQGPL 558
+ + D NDNAP + EP F C+ Q+I +I D D N+S + +
Sbjct: 580 ---TLLLILSDVNDNAP-IPEPRTIFFCERNPKPQVINII---DADLPPNTSPFTAELTH 632
Query: 559 GPDANFTVQDNRDGSASLLLPSRPAPPRHAPYLVPIELWDWGQPALSSTATVTVSVCRCQ 618
G AN+T+Q N S++L + A Y + ++L D T+ VSVC C
Sbjct: 633 GASANWTIQYNDPTQESIILKPKMA-LEVGDYKINLKLMD--NQNKDQVTTLEVSVCDC- 688
Query: 619 PDGSVASCWPEAHLSAAGLSTGALLAIITCVGALLALVVLFVAL--RRQKQEALMVLEEE 676
+G+ C +A AGL A+L I+ + ALL L++L + RR + ++ E+
Sbjct: 689 -EGAAGVC-RKAQPVEAGLQIPAILGILGGILALLILILLLLLFLRRRAVVKEPLLPPED 746
Query: 677 DVRENIITYDDEGGGEEDTEAFDITALQNPDGAAPPAPGPPARRDVLPR-ARVSRQ-PRP 734
D R+N+ YD+EGGGEED + FD++ L A P R DV P V R PRP
Sbjct: 747 DTRDNVYYYDEEGGGEEDQD-FDLSQLHRGLDARPEV----TRNDVAPTLMSVPRYLPRP 801
Query: 735 PGPADVAQLLALRLREADEDPGVPPYDSVQVYGYEGRGSSCGSLSSLGSGSEAGGAPGPA 794
P ++ + L+ AD DP PPYDS+ V+ YEG GS SLSSL S
Sbjct: 802 ANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSE--SDKDQDY 859
Query: 795 EPLDDWGPLFRTLAELYGAKE 815
+ L++WG F+ LA++YG E
Sbjct: 860 DYLNEWGNRFKKLADMYGGGE 880
>gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens]
Length = 829
Score = 279 bits (714), Expect = 7e-75
Identities = 247/805 (30%), Positives = 366/805 (45%), Gaps = 107/805 (13%)
Query: 39 LLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGT----VFVI 94
L R +R WV V E GP P + +L S+ DR + + Y +TG GA + VF +
Sbjct: 102 LRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDR-DTKIFYSITGPGADSPPEGVFAV 160
Query: 95 DEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGP 154
++ TG + + K LDREE A+Y L AV + +E P I V D ND+ P F
Sbjct: 161 EKETGWLLLNKPLDREEIAKYELFGHAVSE-NGASVEDPMNISIIVTDQNDHKPKFTQDT 219
Query: 155 YHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLP------FFSVDPQTGVV 208
+ +V E GTSV+QVTA D DD Y + + Y++ P F++ TG +
Sbjct: 220 FRGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTI 279
Query: 209 RTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVT---LSDVNDNPPKFPQSLYQ 265
+DRE E+ + IQA DM G GSTT V + D NDN P F Y+
Sbjct: 280 SVISSGLDREKVPEYTLTIQATDMDG-----DGSTTTAVAVVEILDANDNAPMFDPQKYE 334
Query: 266 FSVVETAGPGTLVGRLRAQDPDLGDNALM--AYSILDGEGSEAFSISTDLQGRDGLLTVR 323
V E A G V RL D D ++ Y I+ G+ + F+I+T + G+LT R
Sbjct: 335 AHVPENA-VGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTR 393
Query: 324 KPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTV 383
K LDFE++ ++ VE TN + ++ + P A++ V V+D E P F + + V
Sbjct: 394 KGLDFEAKNQHTLYVEVTN---EAPFVLKLP-TSTATIVVHVEDVNEAPVFVPPSKVVEV 449
Query: 384 PENKAPGTLVGQISAADLDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARA 443
E G V +A D D I Y IL DP ++ P+ G + LDRE
Sbjct: 450 QEGIPTGEPVCVYTAEDPDKENQKISYRIL--RDPAGWLAMDPDSGQVTAVGTLDREDEQ 507
Query: 444 W-----HNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQA 498
+ + + VLA + G SP + G
Sbjct: 508 FVRNNIYEVMVLAMDNG--------------------------SPPTTGTG--------- 532
Query: 499 SRVQVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVS-FQGP 557
+ + +D ND+ P + EP +C+ + + QV+ D+D S H S FQ
Sbjct: 533 ---TLLLTLIDVNDHGP-VPEPRQITICNQS---PVRQVLNITDKD---LSPHTSPFQAQ 582
Query: 558 LGPDAN--FTVQDNRDGSASLLLPSRPAPPRHAPYLVPIELWDWGQPALSSTATVTVSVC 615
L D++ +T + N +G +L S + Y V + L D G + +VC
Sbjct: 583 LTDDSDIYWTAEVNEEGDTVVL--SLKKFLKQDTYDVHLSLSDHGNK--EQLTVIRATVC 638
Query: 616 RCQPDGSVASC---WPEAHLSAAGLSTGALLAIITCVGALLALVVLFVALRRQKQEALMV 672
C G V +C W + GA+LA++ L LV+L + +++K + ++
Sbjct: 639 DCH--GHVETCPGPWKGGFILPV---LGAVLALL-----FLLLVLLLLVRKKRKIKEPLL 688
Query: 673 LEEEDVRENIITYDDEGGGEEDTEAFDITALQNPDGAAPPAPGPPARRDVLPR--ARVSR 730
L E+D R+N+ Y +EGGGEED + +DIT L A P R DV P
Sbjct: 689 LPEDDTRDNVFYYGEEGGGEEDQD-YDITQLHRGLEARPEV---VLRNDVAPTIIPTPMY 744
Query: 731 QPRPPGPADVAQLLALRLREADEDPGVPPYDSVQVYGYEGRGSSCGSLSSLGSGSEAGGA 790
+PRP P ++ + L+ A+ DP PPYD++ V+ YEG GS SLSSL S A
Sbjct: 745 RPRPANPDEIGNFIIENLKAANTDPTAPPYDTLLVFDYEGSGSDAASLSSL--TSSASDQ 802
Query: 791 PGPAEPLDDWGPLFRTLAELYGAKE 815
+ L++WG F+ LA++YG E
Sbjct: 803 DQDYDYLNEWGSRFKKLADMYGGGE 827
>gi|4502719 cadherin 13 preproprotein [Homo sapiens]
Length = 713
Score = 213 bits (542), Expect = 6e-55
Identities = 194/611 (31%), Positives = 291/611 (47%), Gaps = 78/611 (12%)
Query: 31 SREHPGPALLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGT 90
+R P P R +RS V + + E P P +GK+ D DR E R+K+ LTG+G
Sbjct: 128 ARTSPVP---RQKRSIVVSPILIPENQRQPFPRDVGKV-VDSDRPE-RSKFRLTGKGVDQ 182
Query: 91 ----VFVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDN 146
+F I+E TG++ VT++LDRE A Y L + D + + LE P + V D NDN
Sbjct: 183 EPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTD-VNGKTLEGPVPLEVIVIDQNDN 241
Query: 147 PPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLP------FFS 200
PIF GPY V E S GT+V+++TA DADDP+ N A L Y + P F
Sbjct: 242 RPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDN-ALLRYNIRQQTPDKPSPNMFY 300
Query: 201 VDPQTGVVRTAIPN--MDRETQE--EFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNP 256
+DP+ G + T + +DRET E ++ ++I+A+DM G GL+G+ T T+ + D ND+
Sbjct: 301 IDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHS 360
Query: 257 PKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNAL--MAYSILDGEGSEAFSISTDLQ 314
PKF + +Q + VE G +V L +D D AY+I++G ++F I T+ Q
Sbjct: 361 PKFTKKEFQ-ATVEEGAVGVIV-NLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQ 418
Query: 315 GRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAY--LRRGPFKDVASVRVAVQDAPEPP 372
+G+L+V KPLD+E ++ ++ N DP + GP A+V + V D E P
Sbjct: 419 TNEGMLSVVKPLDYEISAFHTLLIKVENE--DPLVPDVSYGP-SSTATVHITVLDVNEGP 475
Query: 373 AFTQAAYHLTVPENKAPGTLVGQISAADLDS-PASPIRYSILPHSDPERCFSIQPEEGTI 431
F +T E+ + G+++ ++A D DS IRYS+ + DP +I P GT+
Sbjct: 476 VFYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSV--YKDPAGWLNINPINGTV 533
Query: 432 HTAAPLDREARAWHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIP 491
T A LDRE+ N A L G +P + G
Sbjct: 534 DTTAVLDRESPFVDNSVYTALFLAIDSG----------------------NPPATGTG-- 569
Query: 492 QDSSAQASRVQVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRALDRDEVGNSSH 551
+ I D NDNAP P VCD A ++ ++ A D+D N+
Sbjct: 570 ----------TLLITLEDVNDNAP-FIYPTVAEVCDDAKNLSVV-ILGASDKDLHPNTDP 617
Query: 552 VSFQ--GPLGPDANFTVQ--DNRDGSASLLLPSRPAPPRHAPYLVPIELWDWGQPALSST 607
F+ PD + + +N SLL A Y +PI + D G+P +++
Sbjct: 618 FKFEIHKQAVPDKVWKISKINNTHALVSLL-----QNLNKANYNLPIMVTDSGKPPMTNI 672
Query: 608 ATVTVSVCRCQ 618
+ V VC C+
Sbjct: 673 TDLRVQVCSCR 683
>gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens]
Length = 840
Score = 203 bits (517), Expect = 5e-52
Identities = 190/684 (27%), Positives = 306/684 (44%), Gaps = 87/684 (12%)
Query: 38 ALLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAG----TVFV 93
AL R++R W ++E GP P + ++ SD + Y ++G G +F
Sbjct: 128 ALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNY-TIFYSISGPGVDKEPFNLFY 186
Query: 94 IDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLG 153
I++ TG+I T+S+DRE+ Q+ L A P E P IIK++D NDN P F
Sbjct: 187 IEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAP-EYPLPLIIKIEDDNDNAPYFEHR 245
Query: 154 PYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLP----FFSVDPQTGVVR 209
TVPE GTSV +VTA D D+P ++ +L Y +L +P FS+ P TGV+
Sbjct: 246 VTIFTVPENCRSGTSVGKVTATDLDEPDTLHT-RLKYKILQQIPDHPKHFSIHPDTGVIT 304
Query: 210 TAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVV 269
T P +DRE + + ++++ +DMGG GL + T+T++L D NDNPP F ++ Y V
Sbjct: 305 TTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEVE 364
Query: 270 ETAGPGTLVGRLRAQDPDLGD--NALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLD 327
E ++ R++ QD DL + ++ Y IL G + F ISTD +G+L V KPL+
Sbjct: 365 ENRIDVEIL-RMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLN 423
Query: 328 FESQRSYSFRVEATN-TLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPEN 386
+E R +V N A + P +V V + D+ E P + +
Sbjct: 424 YEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDG 483
Query: 387 KAPGTLVGQISAADLD-SPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREAR--- 442
G + A D + S +RY L D + F I G + T LDRE++
Sbjct: 484 FPAGQELLGYKALDPEISSGEGLRYQKL--GDEDNWFEINQHTGDLRTLKVLDRESKFVK 541
Query: 443 -AWHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRV 501
+N++V+A D+ ++
Sbjct: 542 NNQYNISVVAV----------------------------------------DAVGRSCTG 561
Query: 502 QVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQGPLGPD 561
+ + D ND+APQ+ + + +C + + V++ +D D N F
Sbjct: 562 TLVVHLDDYNDHAPQIDK--EVTICQN---NEDFAVLKPVDPDGPENGPPFQFFLDNSAS 616
Query: 562 ANFTVQDNRDGSASLLLPSRPAPPRHAPYLVPIELWDWGQPALSSTATVTVSVCRC---- 617
N+ +++ +DG ++L + + Y VPI++ D + L +T +TV VC C
Sbjct: 617 KNWNIEE-KDGKTAILRQRQNLDYNY--YSVPIQIKD--RHGLVATHMLTVRVCDCSTPS 671
Query: 618 ---QPDGSVASCWPEAHLSAAGLSTGALLAIITCVGALLALVVLFVALRRQKQEALMVLE 674
D S P L A+LA++ +G++L L +LF + +
Sbjct: 672 ECRMKDKSTRDVRPNVI-----LGRWAILAMV--LGSVLLLCILFTCFCVTAKRTVKKCF 724
Query: 675 EEDV-RENIITYDDEGGGEEDTEA 697
ED+ ++N+I + EG GEE TEA
Sbjct: 725 PEDIAQQNLIVSNTEGPGEEVTEA 748
>gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo
sapiens]
Length = 894
Score = 203 bits (517), Expect = 5e-52
Identities = 190/684 (27%), Positives = 306/684 (44%), Gaps = 87/684 (12%)
Query: 38 ALLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAG----TVFV 93
AL R++R W ++E GP P + ++ SD + Y ++G G +F
Sbjct: 128 ALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNY-TIFYSISGPGVDKEPFNLFY 186
Query: 94 IDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLG 153
I++ TG+I T+S+DRE+ Q+ L A P E P IIK++D NDN P F
Sbjct: 187 IEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAP-EYPLPLIIKIEDDNDNAPYFEHR 245
Query: 154 PYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLP----FFSVDPQTGVVR 209
TVPE GTSV +VTA D D+P ++ +L Y +L +P FS+ P TGV+
Sbjct: 246 VTIFTVPENCRSGTSVGKVTATDLDEPDTLHT-RLKYKILQQIPDHPKHFSIHPDTGVIT 304
Query: 210 TAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVV 269
T P +DRE + + ++++ +DMGG GL + T+T++L D NDNPP F ++ Y V
Sbjct: 305 TTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEVE 364
Query: 270 ETAGPGTLVGRLRAQDPDLGD--NALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLD 327
E ++ R++ QD DL + ++ Y IL G + F ISTD +G+L V KPL+
Sbjct: 365 ENRIDVEIL-RMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLN 423
Query: 328 FESQRSYSFRVEATN-TLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPEN 386
+E R +V N A + P +V V + D+ E P + +
Sbjct: 424 YEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDG 483
Query: 387 KAPGTLVGQISAADLD-SPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREAR--- 442
G + A D + S +RY L D + F I G + T LDRE++
Sbjct: 484 FPAGQELLGYKALDPEISSGEGLRYQKL--GDEDNWFEINQHTGDLRTLKVLDRESKFVK 541
Query: 443 -AWHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRV 501
+N++V+A D+ ++
Sbjct: 542 NNQYNISVVAV----------------------------------------DAVGRSCTG 561
Query: 502 QVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQGPLGPD 561
+ + D ND+APQ+ + + +C + + V++ +D D N F
Sbjct: 562 TLVVHLDDYNDHAPQIDK--EVTICQN---NEDFAVLKPVDPDGPENGPPFQFFLDNSAS 616
Query: 562 ANFTVQDNRDGSASLLLPSRPAPPRHAPYLVPIELWDWGQPALSSTATVTVSVCRC---- 617
N+ +++ +DG ++L + + Y VPI++ D + L +T +TV VC C
Sbjct: 617 KNWNIEE-KDGKTAILRQRQNLDYNY--YSVPIQIKD--RHGLVATHMLTVRVCDCSTPS 671
Query: 618 ---QPDGSVASCWPEAHLSAAGLSTGALLAIITCVGALLALVVLFVALRRQKQEALMVLE 674
D S P L A+LA++ +G++L L +LF + +
Sbjct: 672 ECRMKDKSTRDVRPNVI-----LGRWAILAMV--LGSVLLLCILFTCFCVTAKRTVKKCF 724
Query: 675 EEDV-RENIITYDDEGGGEEDTEA 697
ED+ ++N+I + EG GEE TEA
Sbjct: 725 PEDIAQQNLIVSNTEGPGEEVTEA 748
Score = 32.7 bits (73), Expect = 1.4
Identities = 21/49 (42%), Positives = 24/49 (48%), Gaps = 4/49 (8%)
Query: 761 DSVQVYGYEGRGSSCGSLSSLGSGSEAGGAPGPAEPLDDWGPLFRTLAE 809
D V Y YEG+GS GS+ E G E LD P FRTLA+
Sbjct: 845 DYVCSYNYEGKGSLAGSVGCCSDRQEEEG----LEFLDHLEPKFRTLAK 889
>gi|29570800 cadherin-like 26 isoform a [Homo sapiens]
Length = 832
Score = 194 bits (494), Expect = 2e-49
Identities = 231/820 (28%), Positives = 355/820 (43%), Gaps = 142/820 (17%)
Query: 39 LLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGA------GTVF 92
L R++R WV + EE GP P LIG+L +++ YL++G G G
Sbjct: 49 LRRSKRRWVITTLELEEEDPGPFPKLIGELFNNMSYNMS-LMYLISGPGVDEYPEIGLFS 107
Query: 93 VIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPL 152
+ D G I+V + +DRE + + V+R++ + ++ F I++ D+ND+ P FP
Sbjct: 108 LEDHENGRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPE 167
Query: 153 GPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLPF-----FSVDPQTGV 207
++ TV E + G + Q+ A D D+ + NS +++Y ++ P F VD +G
Sbjct: 168 KEFNITVQENQSAGQPIFQMLAVDLDEENTPNS-QVLYFLISQTPLLKESGFRVDRLSGE 226
Query: 208 VRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFS 267
+R + +D ET +F ++I+A+D G LS +TTV V + + N++ P F Q Y+
Sbjct: 227 IRLS-GCLDYETAPQFTLLIRARDCG--EPSLSSTTTVHVDVQEGNNHRPAFTQENYKVQ 283
Query: 268 VVE-TAGPGTLVGRLRAQDPDLGDNAL--MAYSILDGEGSEAFSISTDLQGRDGLLTVRK 324
+ E A G L RL QD D + ++IL G F ISTD + +G+L V K
Sbjct: 284 IPEGRASQGVL--RLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGILNVIK 341
Query: 325 PLDFESQRSYSFRVEATNTLIDPAYLRRG----PFKDVASVRVAVQ--DAPEPPAFTQAA 378
PLD+E++ + S + N + RG P K AS V+VQ DA +PPAF +
Sbjct: 342 PLDYETRPAQSLIIVVENE-ERLVFCERGKLQPPRKAAASATVSVQVTDANDPPAFHPQS 400
Query: 379 YHLTVPENKAPGTLVGQISAADLDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLD 438
+ + E PGTL+G +A D P S IRY ++ DP S+ G + T P+D
Sbjct: 401 FIVNKEEGARPGTLLGTFNAMD---PDSQIRYELV--HDPANWVSVDKNSGVVITVEPID 455
Query: 439 REA----RAWHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDS 494
RE+ +++ + + A + G+ PPQ +A G
Sbjct: 456 RESPHVNNSFYVIIIHAVDDGF---------------------PPQ-----TATG----- 484
Query: 495 SAQASRVQVAIQTLDENDNAPQLAEPYDTF--VCDSAAPGQLIQVIRALDRDEVGNSSHV 552
+ + D NDN P L P + VC+SA L I A D D S
Sbjct: 485 -------TLMLFLSDINDNVPTL-RPRSRYMEVCESAVHEPL--HIEAEDPDLEPFSDPF 534
Query: 553 SFQ-GPLGPDANFTVQDNRDGSASLLLPSRPAPPRHAPYLVPIELWDWGQPALSSTATVT 611
+F+ +A T + R+ S+ L + + PR YLVP+ + D + LS TV
Sbjct: 535 TFELDNTWGNAEDTWKLGRNWGQSVELLTLRSLPR-GNYLVPLFIGD--KQGLSQKQTVH 591
Query: 612 VSVCRCQPDGSVASCWPEAHLSAAGLSTGALLAIITCVGALLALVVLFVA----LRRQKQ 667
V +C C S +C E + GL GAL + A LA+ +LF+ + K+
Sbjct: 592 VRICPC---ASGLTC-VELADAEVGLHVGALFPVCAAFVA-LAVALLFLLRCYFVLEPKR 646
Query: 668 EALMVLEEEDVRENIITYDDEGGGEEDTEAFDI----TALQNPDGAAPPAPG-------P 716
V +E + ++ Y+ E G D+ AL AA P G P
Sbjct: 647 HGCSVSNDEG-HQTLVMYNAESKGTSAQTWSDVEGQRPALLICTAAAGPTQGVKDLEEVP 705
Query: 717 PARRD------------------------------VLPRARVSRQPRPPGPADVAQLLAL 746
P+ P A + RQ P +A+ L
Sbjct: 706 PSAASQSAQARCALGSWGYGKPFEPRSVKNIHSTPAYPDATMHRQLLAPVEGRMAETLNQ 765
Query: 747 RLREA---DEDPGVPPYDSVQVYGYEGRGSSCGSLSSLGS 783
+L A ++DPG P+ VY EG SLSSL S
Sbjct: 766 KLHVANVLEDDPGYLPH----VYSEEGECGGAPSLSSLAS 801
>gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo
sapiens]
Length = 839
Score = 191 bits (486), Expect = 2e-48
Identities = 181/642 (28%), Positives = 290/642 (45%), Gaps = 82/642 (12%)
Query: 39 LLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAG----TVFVI 94
L R +R W + E GP P+ + ++ SD + Y ++G G +F I
Sbjct: 130 LRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNY-TVFYSISGRGVDKEPLNLFYI 188
Query: 95 DEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGP 154
+ TGN+ T+ +DREE + L+A A A + P I+V+D NDN P+F
Sbjct: 189 ERDTGNLFCTRPVDREEYDVFDLIAYA-STADGYSADLPLPLPIRVEDENDNHPVFTEAI 247
Query: 155 YHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLP----FFSVDPQTGVVRT 210
Y+ V E S GT+V V A D D+P ++ +L Y++L P FSV P TGV+ T
Sbjct: 248 YNFEVLESSRPGTTVGVVCATDRDEPDTMHT-RLKYSILQQTPRSPGLFSVHPSTGVITT 306
Query: 211 AIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVE 270
+DRE +++ ++++ +DM G GL G++T +T++D NDN P F Q+ Y+ V E
Sbjct: 307 VSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVEE 366
Query: 271 TAGPGTLVGRLRAQDPDLGDNA--LMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDF 328
A ++ R+ +D DL + A + ++IL G + F ISTD + +G+L+V KPL++
Sbjct: 367 NAFNVEIL-RIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNY 425
Query: 329 ESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKA 388
E R + + N + R + A V V V+D E P T AA ++ + EN A
Sbjct: 426 EENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLA 485
Query: 389 PGTLVGQISAADLDS-PASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARA---- 443
G+ + A D ++ + +RY L DP+ +I G+I T+ LDRE
Sbjct: 486 VGSKINGYKAYDPENRNGNGLRYKKL--HDPKGWITIDEISGSIITSKILDREVETPKNE 543
Query: 444 WHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQV 503
+N+TVLA + RS G+ +
Sbjct: 544 LYNITVLAID------------------------KDDRSCTGT----------------L 563
Query: 504 AIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQGP-LGPDA 562
A+ D NDN P++ + Y +C P I A+D DE + + F P P+
Sbjct: 564 AVNIEDVNDNPPEILQEY-VVIC---KPKMGYTDILAVDPDEPVHGAPFYFSLPNTSPEI 619
Query: 563 N--FTVQDNRDGSASLLLPSRPAPPRHAPYLVPIELWDWGQPALSSTATVTVSVCRCQPD 620
+ +++ D +A L S Y +PI + D + ++T + V++C C
Sbjct: 620 SRLWSLTKVNDTAARL---SYQKNAGFQEYTIPITVKD--RAGQAATKLLRVNLCECT-- 672
Query: 621 GSVASCWPEAHLSAAGLSTGALLAIITCVGALLALVVLFVAL 662
A STG +L + LL + +LF L
Sbjct: 673 -------HPTQCRATSRSTGVILGKWAILAILLGIALLFSVL 707
>gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo
sapiens]
Length = 896
Score = 191 bits (486), Expect = 2e-48
Identities = 181/642 (28%), Positives = 290/642 (45%), Gaps = 82/642 (12%)
Query: 39 LLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAG----TVFVI 94
L R +R W + E GP P+ + ++ SD + Y ++G G +F I
Sbjct: 130 LRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNY-TVFYSISGRGVDKEPLNLFYI 188
Query: 95 DEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGP 154
+ TGN+ T+ +DREE + L+A A A + P I+V+D NDN P+F
Sbjct: 189 ERDTGNLFCTRPVDREEYDVFDLIAYA-STADGYSADLPLPLPIRVEDENDNHPVFTEAI 247
Query: 155 YHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLP----FFSVDPQTGVVRT 210
Y+ V E S GT+V V A D D+P ++ +L Y++L P FSV P TGV+ T
Sbjct: 248 YNFEVLESSRPGTTVGVVCATDRDEPDTMHT-RLKYSILQQTPRSPGLFSVHPSTGVITT 306
Query: 211 AIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVE 270
+DRE +++ ++++ +DM G GL G++T +T++D NDN P F Q+ Y+ V E
Sbjct: 307 VSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFVEE 366
Query: 271 TAGPGTLVGRLRAQDPDLGDNA--LMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDF 328
A ++ R+ +D DL + A + ++IL G + F ISTD + +G+L+V KPL++
Sbjct: 367 NAFNVEIL-RIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLNY 425
Query: 329 ESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKA 388
E R + + N + R + A V V V+D E P T AA ++ + EN A
Sbjct: 426 EENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENLA 485
Query: 389 PGTLVGQISAADLDS-PASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARA---- 443
G+ + A D ++ + +RY L DP+ +I G+I T+ LDRE
Sbjct: 486 VGSKINGYKAYDPENRNGNGLRYKKL--HDPKGWITIDEISGSIITSKILDREVETPKNE 543
Query: 444 WHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQV 503
+N+TVLA + RS G+ +
Sbjct: 544 LYNITVLAID------------------------KDDRSCTGT----------------L 563
Query: 504 AIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQGP-LGPDA 562
A+ D NDN P++ + Y +C P I A+D DE + + F P P+
Sbjct: 564 AVNIEDVNDNPPEILQEY-VVIC---KPKMGYTDILAVDPDEPVHGAPFYFSLPNTSPEI 619
Query: 563 N--FTVQDNRDGSASLLLPSRPAPPRHAPYLVPIELWDWGQPALSSTATVTVSVCRCQPD 620
+ +++ D +A L S Y +PI + D + ++T + V++C C
Sbjct: 620 SRLWSLTKVNDTAARL---SYQKNAGFQEYTIPITVKD--RAGQAATKLLRVNLCECT-- 672
Query: 621 GSVASCWPEAHLSAAGLSTGALLAIITCVGALLALVVLFVAL 662
A STG +L + LL + +LF L
Sbjct: 673 -------HPTQCRATSRSTGVILGKWAILAILLGIALLFSVL 707
Score = 34.3 bits (77), Expect = 0.48
Identities = 21/53 (39%), Positives = 26/53 (49%), Gaps = 4/53 (7%)
Query: 757 VPPYDSVQVYGYEGRGSSCGSLSSLGSGSEAGGAPGPAEPLDDWGPLFRTLAE 809
+P D V Y YEGRGS GS+ E G + L++ P F TLAE
Sbjct: 843 MPSQDYVLTYNYEGRGSPAGSVGCCSEKQEEDG----LDFLNNLEPKFITLAE 891
>gi|16933557 dachsous 1 precursor [Homo sapiens]
Length = 3298
Score = 187 bits (475), Expect = 3e-47
Identities = 187/573 (32%), Positives = 251/573 (43%), Gaps = 78/573 (13%)
Query: 54 IEEYAGPEPVLIGKLHSDVDRG-EGRTKYLLTGEGAGTVFVIDEATGNIHVTKSLDREEK 112
+ E A P ++ D D+G G+ Y L F ID +G I SLD E +
Sbjct: 482 LPEVALPGSFVVRVTARDPDQGTNGQVTYSLAPGAHTHWFSIDPTSGIITTAASLDYELE 541
Query: 113 AQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQV 172
Q L+ A D PL + + +QD+NDN P F Y+A++PE + GT +QV
Sbjct: 542 PQPQLIVVATD-GGLPPLASSATVSVALQDVNDNEPQFQRTFYNASLPEGTQPGTCFLQV 600
Query: 173 TAHDADDPSYGNSAKLVYTVLDGL-----PFFSVDPQTGVVRTAIPNMDRET-QEEFLVV 226
TA DAD +G L Y++ GL P F +D +G V T +DR+ F
Sbjct: 601 TATDADSGPFG---LLSYSLGAGLGSSGSPPFRIDAHSGDVCTT-RTLDRDQGPSSFDFT 656
Query: 227 IQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDP 286
+ A D GG L V V LSD NDNPP+F Y S+ + PGT V RLRA DP
Sbjct: 657 VTAVDGGG----LKSMVYVKVFLSDENDNPPQFYPREYAASISAQSPPGTAVLRLRAHDP 712
Query: 287 DLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLID 346
D G + ++Y IL G F+ L + GLLTV PL + + A +
Sbjct: 713 DQGSHGRLSYHILAGNSPPLFT----LDEQSGLLTVAWPLARRANSVVQLEIGAED---- 764
Query: 347 PAYLRRGPFKDVASVRV---AVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAADLDS 403
G + S RV V P PP F Q Y +VPE+ APGT VG + A +
Sbjct: 765 -----GGGLQAEPSARVDISIVPGTPTPPIFEQLQYVFSVPEDVAPGTSVGIVQAHNPPG 819
Query: 404 PASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGPERG 463
+P+ S L DP FS+ G + T PLDRE LG
Sbjct: 820 RLAPVTLS-LSGGDPRGLFSLDAVSGLLQTLRPLDREL------------LG-------- 858
Query: 464 WVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQLAEPYDT 523
P+L E V + G+P + +RV+V + D NDN+P P DT
Sbjct: 859 --PVLELE------------VRAGSGVP--PAFAVARVRVLLD--DVNDNSPAFPAPEDT 900
Query: 524 FVC-DSAAPGQLIQVIRALDRDEVGNSSHVSFQGPLGPDANFTVQDNRDGSASLLLPSRP 582
+ + APG I +RALD D G +S V+F G FTV D G L+ P P
Sbjct: 901 VLLPPNTAPGTPIYTLRALDPDS-GVNSRVTFTLLAGGGGAFTV-DPTTGHVRLMRPLGP 958
Query: 583 A-PPRHAPYLVPIELWDWGQPALSSTATVTVSV 614
+ P H + +E D G P +S + V V
Sbjct: 959 SGGPAHE---LELEARDGGSPPRTSHFRLRVVV 988
Score = 166 bits (420), Expect = 8e-41
Identities = 164/567 (28%), Positives = 243/567 (42%), Gaps = 80/567 (14%)
Query: 60 PEPVLIGKLHSDVDRGEG-RTKYLLTGEGAGTVFVIDEATGNIHVTKSLDREEKAQYVLL 118
P P + + D D GE R Y L G G F + +TG + V + LDRE++A++VL
Sbjct: 1560 PGPAALHVVARDPDLGEAARVSYRLASGGDGH-FRLHSSTGALSVVRPLDREQRAEHVLT 1618
Query: 119 AQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDAD 178
A D S P + V D+ND P F Y + E + GTS++ + A
Sbjct: 1619 VVASDHGS-PPRSATQVLTVSVADVNDEAPTFQQQEYSVLLRENNPPGTSLLTLR---AT 1674
Query: 179 DPSYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGG 238
DP G + ++ Y + FS+DP TGV+ T + +DRE QEE + + A+D G
Sbjct: 1675 DPDVGANGQVTYGGVSS-ESFSLDPDTGVL-TTLRALDREEQEEINLTVYAQDRGS--PP 1730
Query: 239 LSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSI 298
TV V + D ND+ P F + V E P TL LRA DPD+G N + Y I
Sbjct: 1731 QLTHVTVRVAVEDENDHAPTFGSAHLSLEVPEGQDPQTLT-MLRASDPDVGANGQLQYRI 1789
Query: 299 LDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDV 358
LDG+ S AF + G +PLD E + ++ R+EA + +
Sbjct: 1790 LDGDPSGAFVLDL----ASGEFGTMRPLDREVEPAFQLRIEARDG-------GQPALSAT 1838
Query: 359 ASVRVAVQDAPE-PPAFTQAAYHLTVPENKAPGTLVGQISAADLDSPAS-PIRYSILPHS 416
+ V V DA + PAF AY + VPE+ GTL+ Q+ A D D+ A+ + Y + +
Sbjct: 1839 LLLTVTVLDANDHAPAFPVPAYSVEVPEDVPAGTLLLQLQAHDPDAGANGHVTYYL--GA 1896
Query: 417 DPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGPERGWVPLLVAEWSAPA 476
F ++P G + TAA LDRE + +V A +
Sbjct: 1897 GTAGAFLLEPSSGELRTAAALDREQCPSYTFSVSAVD----------------------- 1933
Query: 477 APPQRSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAP---------QLAEPYDTFVCD 527
G+A G ++ V V I D ND+AP +L P +F
Sbjct: 1934 --------GAAAG------PLSTTVSVTITVRDVNDHAPTFPTSPLRLRLPRPGPSF--- 1976
Query: 528 SAAPGQLIQVIRALDRDEVGNSSHVSFQGPLGPDANFTVQDNRDGSASLLLPSRPAPPRH 587
+ P + +RA DRD N+S + ++ P TV P P
Sbjct: 1977 -STPTLALATLRAEDRDAGANAS-ILYRLAGTPPPGTTVDSYTGEIRVARSPVALGPRDR 2034
Query: 588 APYLVPIELWDWGQPALSSTATVTVSV 614
++V +L G+PA S+T + V +
Sbjct: 2035 VLFIVATDL---GRPARSATGVIIVGL 2058
Score = 159 bits (401), Expect = 1e-38
Identities = 156/494 (31%), Positives = 220/494 (44%), Gaps = 76/494 (15%)
Query: 71 DVDRGE-GRTKYLLTGEGAGTVFVIDEATG-------NIHVTKSLDREEKAQYVLLAQAV 122
D D G G Y L+G+GAG F ++ G + VT LDRE ++ Y+L +A
Sbjct: 169 DADAGRLGTQGYALSGDGAGETFRLETRPGPDGTPVPELVVTGELDRENRSHYMLQLEAY 228
Query: 123 DRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSY 182
D S P + + + DIND+ P F YHA V E G+ V+QV A DAD
Sbjct: 229 DGGSP-PRRAQALLDVTLLDINDHAPAFNQSRYHAVVSESLAPGSPVLQVFASDADA--- 284
Query: 183 GNSAKLVYTV----LDGLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGG 238
G + + Y + +G FS+D TG+++ P +D E + +V+QA+D G H
Sbjct: 285 GVNGAVTYEINRRQSEGDGPFSIDAHTGLLQLERP-LDFEQRRVHELVVQARDGGAHPE- 342
Query: 239 LSGSTTVTVTLSDVNDNPPK----FPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALM 294
GS VTV + D NDN P F + V E A PG LV R+ DPD GD A +
Sbjct: 343 -LGSAFVTVHVRDANDNQPSMTVIFLSADGSPQVSEAAPPGQLVARISVSDPDDGDFAHV 401
Query: 295 AYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGP 354
S+ GEG A S + L+ V + LD E + +Y+ RV AT++ P
Sbjct: 402 NVSLEGGEGHFALSTQDSVIY---LVCVARRLDREERDAYNLRVTATDS-------GSPP 451
Query: 355 FKDVASVRVAVQDAPE-PPAFTQAAYHLT-VPENKAPGTLVGQISAADLDSPAS-PIRYS 411
+ A+ + V D + PAF + Y +PE PG+ V +++A D D + + YS
Sbjct: 452 LRAEAAFVLHVTDVNDNAPAFDRQLYRPEPLPEVALPGSFVVRVTARDPDQGTNGQVTYS 511
Query: 412 ILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGPERGWVPLLVAE 471
+ P + FSI P G I TAA LD E L V+AT+ G
Sbjct: 512 LAPGAHTH-WFSIDPTSGIITTAASLDYELEPQPQLIVVATDGG---------------- 554
Query: 472 WSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQLAEP-YDTFVCDSAA 530
PP A ++ V VA+Q D NDN PQ Y+ + +
Sbjct: 555 -----LPP---------------LASSATVSVALQ--DVNDNEPQFQRTFYNASLPEGTQ 592
Query: 531 PGQLIQVIRALDRD 544
PG + A D D
Sbjct: 593 PGTCFLQVTATDAD 606
Score = 154 bits (389), Expect = 3e-37
Identities = 139/491 (28%), Positives = 209/491 (42%), Gaps = 73/491 (14%)
Query: 70 SDVDRGEGRTKYLLTGEGAGTVFVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRP 129
+DVD G Y+L+ G F + G + +T LD E+ +Y L A D P
Sbjct: 2301 NDVDSGPVLW-YVLSPSGPQDPFSVGRYGGRVSLTGPLDFEQCDRYQLQLLAHDG----P 2355
Query: 130 LEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLV 189
E + + V+D+NDN P F Y + E + G++++ V+A D D + G+ + +
Sbjct: 2356 HEGRANLTVLVEDVNDNAPAFSQSLYQVMLLEHTPPGSAILSVSATDRDSGANGHISYHL 2415
Query: 190 YTVLDGLPFFSVDPQTGVVRTAIPN--MDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTV 247
+ DG FSVDP G + T + + + VV++A+D G G + TV V
Sbjct: 2416 ASPADG---FSVDPNNGTLFTIVGTVALGHDGSGAVDVVLEARDHGAP--GRAARATVHV 2470
Query: 248 TLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLG-DNALMAYSILDGEGSEA 306
L D ND+ P F S Y+ +V E PG+ + L A D D +A + YSI+ G
Sbjct: 2471 QLQDQNDHAPSFTLSHYRVAVTEDLPPGSTLLTLEATDADGSRSHAAVDYSIISGNWGRV 2530
Query: 307 FSISTDLQGRD----------GLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFK 356
F + L G L + +PLDFES Y+ V A + + P
Sbjct: 2531 FQLEPRLAEAGESAGPGPRALGCLVLLEPLDFESLTQYNLTVAAADR-------GQPPQS 2583
Query: 357 DVASVRVAVQDAPE-PPAFTQAAYHLTVPENKAPGTLVGQISAADLD-SPASPIRYSILP 414
V V V V D + PP FT+A+Y +TVPE+ G + + A+D D P +R+++
Sbjct: 2584 SVVPVTVTVLDVNDNPPVFTRASYRVTVPEDTPVGAELLHVEASDADPGPHGLVRFTV-S 2642
Query: 415 HSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGPERGWVPLLVAEWSA 474
DP F + GT+ A LD E +A H L V A +
Sbjct: 2643 SGDPSGLFELDESSGTLRLAHALDCETQARHQLVVQAAD--------------------- 2681
Query: 475 PAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQL-AEPYDTFVCDSAAPGQ 533
P G A + V I+ D ND+ P T V ++ PG
Sbjct: 2682 --------PAG----------AHFALAPVTIEVQDVNDHGPAFPLNLLSTSVAENQPPGT 2723
Query: 534 LIQVIRALDRD 544
L+ + A+D D
Sbjct: 2724 LVTTLHAIDGD 2734
Score = 150 bits (380), Expect = 4e-36
Identities = 148/527 (28%), Positives = 223/527 (42%), Gaps = 70/527 (13%)
Query: 94 IDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKV--QDINDNPPIFP 151
+D TG + + LDRE +LL +A DR +N + +V D NDN P+F
Sbjct: 1488 LDARTGALSAPRGLDRETTPALLLLVEATDRPANASRRRAARVSARVFVTDENDNAPVFA 1547
Query: 152 LGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLP-FFSVDPQTGVVRT 210
P +PE G + + V A D P G +A++ Y + G F + TG +
Sbjct: 1548 -SPSRVRLPEDQPPGPAALHVVARD---PDLGEAARVSYRLASGGDGHFRLHSSTGALSV 1603
Query: 211 AIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVE 270
P +DRE + E ++ + A D G S + +TV+++DVND P F Q Y + E
Sbjct: 1604 VRP-LDREQRAEHVLTVVASDHGSPPR--SATQVLTVSVADVNDEAPTFQQQEYSVLLRE 1660
Query: 271 TAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFES 330
PGT + LRA DPD+G N + Y G SE+FS+ D G+LT + LD E
Sbjct: 1661 NNPPGTSLLTLRATDPDVGANGQVTYG---GVSSESFSLDPD----TGVLTTLRALDREE 1713
Query: 331 QRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPE-PPAFTQAAYHLTVPENKAP 389
Q + V A + P +VRVAV+D + P F A L VPE + P
Sbjct: 1714 QEEINLTVYAQDRGSPPQLTH-------VTVRVAVEDENDHAPTFGSAHLSLEVPEGQDP 1766
Query: 390 GTLVGQISAADLDSPAS-PIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLT 448
TL + A+D D A+ ++Y IL DP F + G T PLDRE L
Sbjct: 1767 QTLT-MLRASDPDVGANGQLQYRIL-DGDPSGAFVLDLASGEFGTMRPLDREVEPAFQLR 1824
Query: 449 VLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTL 508
+ A + G A ++ + + + L
Sbjct: 1825 IEARDGG--------------------------------------QPALSATLLLTVTVL 1846
Query: 509 DENDNAPQLAEP-YDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQGPLGPDANFTVQ 567
D ND+AP P Y V + G L+ ++A D D G + HV++ G F ++
Sbjct: 1847 DANDHAPAFPVPAYSVEVPEDVPAGTLLLQLQAHDPD-AGANGHVTYYLGAGTAGAFLLE 1905
Query: 568 DNRDGSASLLLPSRPAPPRHAPYLVPIELWDWGQPALSSTATVTVSV 614
+ + R P + + ++ G LS+T +VT++V
Sbjct: 1906 PSSGELRTAAALDREQCPSYTFSVSAVDGAAAG--PLSTTVSVTITV 1950
Score = 150 bits (379), Expect = 5e-36
Identities = 141/502 (28%), Positives = 215/502 (42%), Gaps = 79/502 (15%)
Query: 77 GRTKYLLTGEGAGTVFVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEF 136
G Y L EGA + F ++ +G + V +LDRE + Y+L AV + +
Sbjct: 1030 GPITYHLAAEGASSPFGLEPQSGWLWVRAALDREAQELYILKVMAVSGSKAELGQQTGTA 1089
Query: 137 IIKVQDINDNP--PIFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLD 194
++V +N N P P V E GTSV +V A D D G + + +
Sbjct: 1090 TVRVSILNQNEHSPRLSEDPTFLAVAENQPPGTSVGRVFATDRDSGPNGRLTYSLQQLSE 1149
Query: 195 GLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVND 254
F + PQTG V T + +DRE Q + +++Q +D G +G TV V + D+ND
Sbjct: 1150 DSKAFRIHPQTGEV-TTLQTLDREQQSSYQLLVQVQDGGSPPRSTTG--TVHVAVLDLND 1206
Query: 255 NPPKFPQSL------YQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGSEAFS 308
N P F Q+ V + PGTLV L+A+DPD G+N + Y+ L G GSE FS
Sbjct: 1207 NSPTFLQASGAAGGGLPIQVPDRVPPGTLVTTLQAKDPDEGENGTILYT-LTGPGSELFS 1265
Query: 309 ISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDA 368
L G L PL R E + ++ + +G AS+++ VQ
Sbjct: 1266 ----LHPHSGELLTAAPL---------IRAERPHYVLTLSAHDQGSPPRSASLQLLVQVL 1312
Query: 369 P--------------EPPAFTQAAYHLTVPENKAPGTLVGQISAADLDSPASPIRYSILP 414
P +P A +T E PG+L+G ++A + + + Y+++
Sbjct: 1313 PSARLAEPPPDLAERDPAAPVPVVLTVTAAEGLRPGSLLGSVAAPE-PAGVGALTYTLVG 1371
Query: 415 HSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGPERGWVPLLVAEWSA 474
+DPE F++ G ++ A PLD E
Sbjct: 1372 GADPEGTFALDAASGRLYLARPLDFE---------------------------------- 1397
Query: 475 PAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQLA-EPYDTFVCDSAAPGQ 533
A PP R+ A G P + A+ RVQV +Q DEN++AP A +P + ++ PG
Sbjct: 1398 -AGPPWRALTVRAEG-PGGAGARLLRVQVQVQ--DENEHAPAFARDPLALALPENPEPGA 1453
Query: 534 LIQVIRALDRDEVGNSSHVSFQ 555
+ RA D D G +S V ++
Sbjct: 1454 ALYTFRASDADGPGPNSDVRYR 1475
Score = 147 bits (372), Expect = 3e-35
Identities = 121/359 (33%), Positives = 163/359 (45%), Gaps = 41/359 (11%)
Query: 85 GEGAGTVFVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQ--- 141
GE AG A G + + + LD E QY L A DR +PP ++ V
Sbjct: 2541 GESAGPG---PRALGCLVLLEPLDFESLTQYNLTVAAADRG-----QPPQSSVVPVTVTV 2592
Query: 142 -DINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLP--F 198
D+NDNPP+F Y TVPE + VG ++ V A DAD +G + +TV G P
Sbjct: 2593 LDVNDNPPVFTRASYRVTVPEDTPVGAELLHVEASDADPGPHG---LVRFTVSSGDPSGL 2649
Query: 199 FSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPK 258
F +D +G +R A +D ETQ +V+QA D G L+ VT+ + DVND+ P
Sbjct: 2650 FELDESSGTLRLAHA-LDCETQARHQLVVQAADPAGAHFALA---PVTIEVQDVNDHGPA 2705
Query: 259 FPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDG----EGSEAFSISTDLQ 314
FP +L SV E PGTLV L A D D G + YS+L+ EG EAF++++
Sbjct: 2706 FPLNLLSTSVAENQPPGTLVTTLHAIDGDAGAFGRLRYSLLEAGPGPEGREAFALNSS-- 2763
Query: 315 GRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPE-PPA 373
G L R P D+E S+ V A + G +V V V E P
Sbjct: 2764 --TGELRARVPFDYEHTESFRLLVGAADA---------GNLSASVTVSVLVTGEDEYDPV 2812
Query: 374 FTQAAYHLTVPENKAPGTLVGQISAADLDSPASPIRYSILPHSDPERCFSIQPEEGTIH 432
F A+H VPE G +G + A D D A + L S P F I G ++
Sbjct: 2813 FLAPAFHFQVPEGARRGHSLGHVQATDEDGGADGLVLYSLATSSP--YFGINQTTGALY 2869
Score = 144 bits (364), Expect = 3e-34
Identities = 156/561 (27%), Positives = 242/561 (43%), Gaps = 75/561 (13%)
Query: 64 LIGKLHSDVDRGEGRTKYLLTG--EGAGTVFVIDEATGNIHVTKSLDREEKAQYVLL--- 118
L+G + + G G Y L G + GT F +D A+G +++ + LD E + L
Sbjct: 1350 LLGSVAAPEPAGVGALTYTLVGGADPEGT-FALDAASGRLYLARPLDFEAGPPWRALTVR 1408
Query: 119 AQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDAD 178
A+ A R L ++VQD N++ P F P +PE G ++ A DAD
Sbjct: 1409 AEGPGGAGARLLRVQ----VQVQDENEHAPAFARDPLALALPENPEPGAALYTFRASDAD 1464
Query: 179 DPSYGNSAKLVYTVL---DGLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGH 235
P G ++ + Y +L +P +D +TG + +A +DRET L++++A D +
Sbjct: 1465 GP--GPNSDVRYRLLRQEPPVPALRLDARTGAL-SAPRGLDRETTPALLLLVEATDRPAN 1521
Query: 236 MG-GLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALM 294
+ + V ++D NDN P F S + + E PG + A+DPDLG+ A +
Sbjct: 1522 ASRRRAARVSARVFVTDENDNAPVF-ASPSRVRLPEDQPPGPAALHVVARDPDLGEAARV 1580
Query: 295 AYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGP 354
+Y + G G F L G L+V +PLD E + + V A++ P +
Sbjct: 1581 SYRLASG-GDGHFR----LHSSTGALSVVRPLDREQRAEHVLTVVASDHGSPPRSATQVL 1635
Query: 355 FKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAADLDSPASPIRYSILP 414
VA V E P F Q Y + + EN PGT + + A D D A+ +
Sbjct: 1636 TVSVADVN------DEAPTFQQQEYSVLLRENNPPGTSLLTLRATDPDVGANG---QVTY 1686
Query: 415 HSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGPERGWVPLLVAEWSA 474
FS+ P+ G + T LDRE + NLTV A + G
Sbjct: 1687 GGVSSESFSLDPDTGVLTTLRALDREEQEEINLTVYAQDRG------------------- 1727
Query: 475 PAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQLAEPYDTFVCDSAAPGQL 534
+PPQ + V V+VA++ DEND+AP + + Q
Sbjct: 1728 --SPPQLTHV---------------TVRVAVE--DENDHAPTFGSAHLSLEVPEGQDPQT 1768
Query: 535 IQVIRALDRDEVGNSSHVSFQGPLGPDANFTVQDNRDGSASLLLP-SRPAPPRHAPYLVP 593
+ ++RA D D VG + + ++ G + V D G + P R P + +
Sbjct: 1769 LTMLRASDPD-VGANGQLQYRILDGDPSGAFVLDLASGEFGTMRPLDREVEP---AFQLR 1824
Query: 594 IELWDWGQPALSSTATVTVSV 614
IE D GQPALS+T +TV+V
Sbjct: 1825 IEARDGGQPALSATLLLTVTV 1845
Score = 144 bits (363), Expect = 3e-34
Identities = 165/580 (28%), Positives = 242/580 (41%), Gaps = 92/580 (15%)
Query: 60 PEPVLIGKLHSDVDRGEGRT-KYLLT---GEGAGTVFVIDEATGNIHVTKSLDREEKAQY 115
P LIG + + + G Y ++ G G GT IDE +G + + LDRE++ +Y
Sbjct: 56 PAGTLIGDISAGLPAGTAAPLMYFISAQEGSGVGTDLAIDEHSGVVRTARVLDREQRDRY 115
Query: 116 VLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAH 175
A D A+ E ++V DIND+ P FP VPE + GT A
Sbjct: 116 RFTAVTPDGAT-------VEVTVRVADINDHAPAFPQARAALQVPEHTAFGTRYPLEPAR 168
Query: 176 DADDPSYGNSAKLVYTVLDGL-PFFSVDPQTGVVRTAIPNM------DRETQEEFLVVIQ 228
DAD G + DG F ++ + G T +P + DRE + +++ ++
Sbjct: 169 DADAGRLGTQGYALSG--DGAGETFRLETRPGPDGTPVPELVVTGELDRENRSHYMLQLE 226
Query: 229 AKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDL 288
A D G + VTL D+ND+ P F QS Y V E+ PG+ V ++ A D D
Sbjct: 227 AYDGGSPPR--RAQALLDVTLLDINDHAPAFNQSRYHAVVSESLAPGSPVLQVFASDADA 284
Query: 289 GDNALMAYSI--LDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLID 346
G N + Y I EG FSI GLL + +PLDFE +R + V+A +
Sbjct: 285 GVNGAVTYEINRRQSEGDGPFSI----DAHTGLLQLERPLDFEQRRVHELVVQARD---G 337
Query: 347 PAYLRRGPFKDVASVRVAVQDAPEPPA-FTQAAYHLTVPENKAPGTLVGQISAADLDSPA 405
A+ G VR A + P F A V E PG LV +IS +D D
Sbjct: 338 GAHPELGSAFVTVHVRDANDNQPSMTVIFLSADGSPQVSEAAPPGQLVARISVSDPDD-- 395
Query: 406 SPIRYSILPHSDPERCFSIQPEEGTIH---TAAPLDREARAWHNLTVLATELGWSWGPER 462
+ + E F++ ++ I+ A LDRE R +NL V AT+ G
Sbjct: 396 GDFAHVNVSLEGGEGHFALSTQDSVIYLVCVARRLDREERDAYNLRVTATDSG------- 448
Query: 463 GWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAP----QLA 518
+PP R A+A+ V + D NDNAP QL
Sbjct: 449 --------------SPPLR--------------AEAAFV---LHVTDVNDNAPAFDRQLY 477
Query: 519 EPYDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQGPLGPDANFTVQDNRDG----SA 574
P + + A PG + + A D D+ G + V++ G ++ D G +A
Sbjct: 478 RPEP--LPEVALPGSFVVRVTARDPDQ-GTNGQVTYSLAPGAHTHWFSIDPTSGIITTAA 534
Query: 575 SLLLPSRPAPPRHAPYLVPIELWDWGQPALSSTATVTVSV 614
SL P P + + D G P L+S+ATV+V++
Sbjct: 535 SLDYELEPQPQ------LIVVATDGGLPPLASSATVSVAL 568
Score = 136 bits (342), Expect = 9e-32
Identities = 143/519 (27%), Positives = 215/519 (41%), Gaps = 71/519 (13%)
Query: 60 PEPVLIGKL-----HSDVDRG-EGRTKYLLTGEGAGTVFVIDEATGNIHVTKSLDREEKA 113
PE V G L D D G G Y L G G F+++ ++G + +LDRE+
Sbjct: 1865 PEDVPAGTLLLQLQAHDPDAGANGHVTYYL-GAGTAGAFLLEPSSGELRTAAALDREQCP 1923
Query: 114 QYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMS-NVGTSVIQV 172
Y AVD A+ PL I V+D+ND+ P FP P +P + T + +
Sbjct: 1924 SYTFSVSAVDGAAAGPLSTTVSVTITVRDVNDHAPTFPTSPLRLRLPRPGPSFSTPTLAL 1983
Query: 173 TAHDADDPSYGNSAKLVYTVL-DGLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKD 231
A+D G +A ++Y + P +VD TG +R A + ++ L ++ A D
Sbjct: 1984 ATLRAEDRDAGANASILYRLAGTPPPGTTVDSYTGEIRVARSPVALGPRDRVLFIV-ATD 2042
Query: 232 MGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDN 291
+G +G + V L + P+FP++ + ++ E A PGT + RA G N
Sbjct: 2043 LGRPARSATG--VIIVGLQGEAERGPRFPRASSEATIRENAPPGTPIVSPRAVHAG-GTN 2099
Query: 292 ALMAYSILDGEGSEAFSISTDLQGRDGLLTVR--KPLDFESQRSYSFRVEATNTLIDPAY 349
+ YSIL G FSI Q G +TVR + LDFE ++A +
Sbjct: 2100 GPITYSILSGNEKGTFSI----QPSTGAITVRSAEGLDFEVSPRLRLVLQAES------- 2148
Query: 350 LRRGPFKDVASVRVAVQDAPE-PPAFTQAAYHLTVPENKAPGTLVGQISAADLD-SPASP 407
G + + +QDA + P F + Y +PE++ + Q+ A DLD
Sbjct: 2149 ---GGAFAFTVLTLTLQDANDNAPRFLRPHYVAFLPESRPLEGPLLQVEADDLDQGSGGQ 2205
Query: 408 IRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGPERGWVPL 467
I YS+ F + P GTI T A LDRE A L ++AT+ G
Sbjct: 2206 ISYSLAASQPARGLFHVDPTTGTITTTAILDREIWAETRLVLMATDRG------------ 2253
Query: 468 LVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQLAEPYDTFVCD 527
+PA VGSA + + +D NDN P + +P++ V +
Sbjct: 2254 ------SPAL------VGSAT--------------LTVMVIDTNDNRPTIPQPWELRVSE 2287
Query: 528 SAAPGQLIQVIRALDRDEVGNSSHVSFQGPLGPDANFTV 566
A G I + D D +V P GP F+V
Sbjct: 2288 DALLGSEIAQVTGNDVDSGPVLWYV--LSPSGPQDPFSV 2324
Score = 130 bits (326), Expect = 6e-30
Identities = 157/567 (27%), Positives = 238/567 (41%), Gaps = 108/567 (19%)
Query: 79 TKYLLTGEGAGTVFVIDEATGNIHV--TKSLDREEKAQYVLLAQAVDRASNRPLEPPSEF 136
T +L+G GT F I +TG I V + LD E + L+ QA + +
Sbjct: 2103 TYSILSGNEKGT-FSIQPSTGAITVRSAEGLDFEVSPRLRLVLQAESGGAFAF----TVL 2157
Query: 137 IIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGL 196
+ +QD NDN P F Y A +PE + ++QV +ADD G+ ++ Y++
Sbjct: 2158 TLTLQDANDNAPRFLRPHYVAFLPESRPLEGPLLQV---EADDLDQGSGGQISYSLAASQ 2214
Query: 197 P---FFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVN 253
P F VDP TG + T +DRE E +V+ A D G L GS T+TV + D N
Sbjct: 2215 PARGLFHVDPTTGTITTTAI-LDREIWAETRLVLMATDRGSP--ALVGSATLTVMVIDTN 2271
Query: 254 DNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDL 313
DN P PQ ++ V E A G+ + ++ D D G ++ Y + + FS+
Sbjct: 2272 DNRPTIPQP-WELRVSEDALLGSEIAQVTGNDVDSGP--VLWYVLSPSGPQDPFSV---- 2324
Query: 314 QGR-DGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPE-P 371
GR G +++ PLDFE Y ++ A + GP + A++ V V+D +
Sbjct: 2325 -GRYGGRVSLTGPLDFEQCDRYQLQLLAHD----------GPHEGRANLTVLVEDVNDNA 2373
Query: 372 PAFTQAAYHLTVPENKAPGTLVGQISAADLDSPASP-IRYSILPHSDPERCFSIQPEEGT 430
PAF+Q+ Y + + E+ PG+ + +SA D DS A+ I Y + + P FS+ P GT
Sbjct: 2374 PAFSQSLYQVMLLEHTPPGSAILSVSATDRDSGANGHISYHL---ASPADGFSVDPNNGT 2430
Query: 431 IHTAAPLDREARAWHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGI 490
+ T++ T G V L + AP
Sbjct: 2431 L---------------FTIVGTVALGHDGSGAVDVVLEARDHGAPG-------------- 2461
Query: 491 PQDSSAQASRVQVAIQTLDENDNAPQLA-EPYDTFVCDSAAPGQLIQVIRALDRDEVGNS 549
+A+R V +Q D+ND+AP Y V + PG + + A D D G+
Sbjct: 2462 ------RAARATVHVQLQDQNDHAPSFTLSHYRVAVTEDLPPGSTLLTLEATDAD--GSR 2513
Query: 550 SHVSFQGPLGPDANFTVQDNRDGSASLLLP-------SRPAPPRHAPYLVPIELWDW--- 599
SH + ++++ G L P S PR LV +E D+
Sbjct: 2514 SHAA--------VDYSIISGNWGRVFQLEPRLAEAGESAGPGPRALGCLVLLEPLDFESL 2565
Query: 600 ------------GQPALSSTATVTVSV 614
GQP SS VTV+V
Sbjct: 2566 TQYNLTVAAADRGQPPQSSVVPVTVTV 2592
Score = 129 bits (324), Expect = 1e-29
Identities = 151/555 (27%), Positives = 230/555 (41%), Gaps = 75/555 (13%)
Query: 71 DVDRGE-GRTKYLLTGEGAGTVFVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRP 129
D D+G GR Y + + +F +DE +G + V L R + L A D
Sbjct: 711 DPDQGSHGRLSYHILAGNSPPLFTLDEQSGLLTVAWPLARRANSVVQLEIGAED-GGGLQ 769
Query: 130 LEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLV 189
EP + I + PPIF Y +VPE GTSV V AH+ G A +
Sbjct: 770 AEPSARVDISIVPGTPTPPIFEQLQYVFSVPEDVAPGTSVGIVQAHNPP----GRLAPVT 825
Query: 190 YTVLDGLP--FFSVDPQTGVVRTAIPNMDRETQEEFLVV-IQAKDMGGHMGGLSGSTTVT 246
++ G P FS+D +G+++T P +DRE L + ++A G + V
Sbjct: 826 LSLSGGDPRGLFSLDAVSGLLQTLRP-LDRELLGPVLELEVRA---GSGVPPAFAVARVR 881
Query: 247 VTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGSEA 306
V L DVNDN P FP + PGT + LRA DPD G N+ + +++L G G A
Sbjct: 882 VLLDDVNDNSPAFPAPEDTVLLPPNTAPGTPIYTLRALDPDSGVNSRVTFTLLAG-GGGA 940
Query: 307 FSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQ 366
F++ G + + +PL ++ +EA + P R F+ +RV VQ
Sbjct: 941 FTVDP----TTGHVRLMRPLGPSGGPAHELELEARDGGSPP---RTSHFR----LRVVVQ 989
Query: 367 DAPE---PPAFTQAAYHLTVPENKAPGTLVGQISAADLDSPASPIRYSILPH--SDPERC 421
D P F Y + +P GT V Q+ A D PI Y + S P
Sbjct: 990 DVGTRGLAPRFNSPTYRVDLPSGTTAGTQVLQVQAQAPD--GGPITYHLAAEGASSP--- 1044
Query: 422 FSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQR 481
F ++P+ G + A LDREA+ + L V+A
Sbjct: 1045 FGLEPQSGWLWVRAALDREAQELYILKVMAVS---------------------------- 1076
Query: 482 SPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQLAE-PYDTFVCDSAAPGQLIQVIRA 540
GS + Q + RV + L++N+++P+L+E P V ++ PG + + A
Sbjct: 1077 ---GSKAELGQQTGTATVRVSI----LNQNEHSPRLSEDPTFLAVAENQPPGTSVGRVFA 1129
Query: 541 LDRDEVGNSSHVSFQGPLGPDAN-FTVQDNRDGSASLLLPSRPAPPRHAPYLVPIELWDW 599
DRD N L D+ F + +L R + + Y + +++ D
Sbjct: 1130 TDRDSGPNGRLTYSLQQLSEDSKAFRIHPQTGEVTTLQTLDR---EQQSSYQLLVQVQDG 1186
Query: 600 GQPALSSTATVTVSV 614
G P S+T TV V+V
Sbjct: 1187 GSPPRSTTGTVHVAV 1201
Score = 127 bits (319), Expect = 4e-29
Identities = 167/638 (26%), Positives = 256/638 (40%), Gaps = 95/638 (14%)
Query: 51 FFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEATGNIHVTKSLDRE 110
F V E+ A V I + H+ R T L G+ G +F +D +G + + LDRE
Sbjct: 797 FSVPEDVAPGTSVGIVQAHNPPGRLAPVTLSLSGGDPRG-LFSLDAVSGLLQTLRPLDRE 855
Query: 111 EKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVI 170
VL + + P + + + D+NDN P FP +P + GT +
Sbjct: 856 LLGP-VLELEVRAGSGVPPAFAVARVRVLLDDVNDNSPAFPAPEDTVLLPPNTAPGTPIY 914
Query: 171 QVTAHDADDPSYGNSAKLVYTVL-DGLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVIQA 229
+ A D D G ++++ +T+L G F+VDP TG VR P + + ++A
Sbjct: 915 TLRALDPDS---GVNSRVTFTLLAGGGGAFTVDPTTGHVRLMRP-LGPSGGPAHELELEA 970
Query: 230 KDMGGHMGGLSGSTT---VTVTLSDVNDN--PPKFPQSLYQFSVVETAGPGTLVGRLRAQ 284
+D GG T+ + V + DV P+F Y+ + GT V +++AQ
Sbjct: 971 RD-----GGSPPRTSHFRLRVVVQDVGTRGLAPRFNSPTYRVDLPSGTTAGTQVLQVQAQ 1025
Query: 285 DPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTL 344
PD G + Y + S F L+ + G L VR LD E+Q Y +V A
Sbjct: 1026 APDGGP---ITYHLAAEGASSPFG----LEPQSGWLWVRAALDREAQELYILKVMA---- 1074
Query: 345 IDPAYLRRGPFKDVASVRVAVQDAPE-PPAFTQAAYHLTVPENKAPGTLVGQISAADLDS 403
+ + G A+VRV++ + E P ++ L V EN+ PGT VG++ A D DS
Sbjct: 1075 VSGSKAELGQQTGTATVRVSILNQNEHSPRLSEDPTFLAVAENQPPGTSVGRVFATDRDS 1134
Query: 404 -PASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGPER 462
P + YS+ S+ + F I P+ G + T LDRE ++ + L V + G
Sbjct: 1135 GPNGRLTYSLQQLSEDSKAFRIHPQTGEVTTLQTLDREQQSSYQLLVQVQDGG------- 1187
Query: 463 GWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQLAEPYD 522
P RS G+ V + LD NDN+P +
Sbjct: 1188 ---------------SPPRSTTGT----------------VHVAVLDLNDNSPTFLQASG 1216
Query: 523 TF-------VCDSAAPGQLIQVIRALDRDEVGNSSHVSFQGPLGPDANFTVQDNRDGSAS 575
V D PG L+ ++A D DE N + GP + G
Sbjct: 1217 AAGGGLPIQVPDRVPPGTLVTTLQAKDPDEGENGT--ILYTLTGPGSELFSLHPHSGELL 1274
Query: 576 LLLPSRPAPPRHAPYLVPIELWDWGQPALSSTATVTVSVC----RCQPDGSVASCWPEAH 631
P A H Y++ + D G P S++ + V V +P +A P A
Sbjct: 1275 TAAPLIRAERPH--YVLTLSAHDQGSPPRSASLQLLVQVLPSARLAEPPPDLAERDPAAP 1332
Query: 632 L-------SAAGLSTGALLAIITC-----VGALLALVV 657
+ +A GL G+LL + VGAL +V
Sbjct: 1333 VPVVLTVTAAEGLRPGSLLGSVAAPEPAGVGALTYTLV 1370
Score = 124 bits (311), Expect = 4e-28
Identities = 131/460 (28%), Positives = 199/460 (43%), Gaps = 47/460 (10%)
Query: 71 DVDRGEG-RTKY-LLTGEGAGTVFVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNR 128
D+D+G G + Y L + A +F +D TG I T LDRE A+ L+ A DR S
Sbjct: 2197 DLDQGSGGQISYSLAASQPARGLFHVDPTTGTITTTAILDREIWAETRLVLMATDRGS-P 2255
Query: 129 PLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKL 188
L + + V D NDN P P P+ V E + +G+ + QVT +D D + L
Sbjct: 2256 ALVGSATLTVMVIDTNDNRPTIP-QPWELRVSEDALLGSEIAQVTGNDVD-----SGPVL 2309
Query: 189 VYTVLDGLPF--FSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVT 246
Y + P FSV G V P +D E + + + + A H G G +T
Sbjct: 2310 WYVLSPSGPQDPFSVGRYGGRVSLTGP-LDFEQCDRYQLQLLA-----HDGPHEGRANLT 2363
Query: 247 VTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGSEA 306
V + DVNDN P F QSLYQ ++E PG+ + + A D D G N ++Y + ++
Sbjct: 2364 VLVEDVNDNAPAFSQSLYQVMLLEHTPPGSAILSVSATDRDSGANGHISYHL--ASPADG 2421
Query: 307 FSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQ 366
FS+ + G + L + + +EA + R A+V V +Q
Sbjct: 2422 FSVDPN-NGTLFTIVGTVALGHDGSGAVDVVLEARDHGAPGRAAR-------ATVHVQLQ 2473
Query: 367 DAPE-PPAFTQAAYHLTVPENKAPGTLVGQISAADLDSPAS--PIRYSILPHSDPERCFS 423
D + P+FT + Y + V E+ PG+ + + A D D S + YSI+ + R F
Sbjct: 2474 DQNDHAPSFTLSHYRVAVTEDLPPGSTLLTLEATDADGSRSHAAVDYSII-SGNWGRVFQ 2532
Query: 424 IQPE--------------EGTIHTAAPLDREARAWHNLTVLATELGWSWGPERGWVPLLV 469
++P G + PLD E+ +NLTV A + G P+ VP+ V
Sbjct: 2533 LEPRLAEAGESAGPGPRALGCLVLLEPLDFESLTQYNLTVAAADRGQP--PQSSVVPVTV 2590
Query: 470 AEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTLD 509
PP + V +P+D+ A + V D
Sbjct: 2591 TVLDVNDNPPVFTRASYRVTVPEDTPVGAELLHVEASDAD 2630
Score = 122 bits (305), Expect = 2e-27
Identities = 161/603 (26%), Positives = 246/603 (40%), Gaps = 80/603 (13%)
Query: 53 VIEEYAGPEPVLIGKLHSDVDRG-EGRTKYLLTGEGAGTVFVIDEATGNIHVTKSLDREE 111
++ E P L+ +D D G G+ Y G + F +D TG + ++LDREE
Sbjct: 1657 LLRENNPPGTSLLTLRATDPDVGANGQVTY---GGVSSESFSLDPDTGVLTTLRALDREE 1713
Query: 112 KAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQ 171
+ + L A DR S L + + V+D ND+ P F VPE + T
Sbjct: 1714 QEEINLTVYAQDRGSPPQLTHVT-VRVAVEDENDHAPTFGSAHLSLEVPEGQDPQT---- 1768
Query: 172 VTAHDADDPSYGNSAKLVYTVLDGLPF--FSVDPQTGVVRTAIPNMDRETQEEFLVVIQA 229
+T A DP G + +L Y +LDG P F +D +G T P +DRE + F + I+A
Sbjct: 1769 LTMLRASDPDVGANGQLQYRILDGDPSGAFVLDLASGEFGTMRP-LDREVEPAFQLRIEA 1827
Query: 230 KDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLG 289
+D G LS + +TVT+ D ND+ P FP Y V E GTL+ +L+A DPD G
Sbjct: 1828 RD--GGQPALSATLLLTVTVLDANDHAPAFPVPAYSVEVPEDVPAGTLLLQLQAHDPDAG 1885
Query: 290 DNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAY 349
N + Y + G G+ + L+ G L LD E SY+F V A +D A
Sbjct: 1886 ANGHVTYYL--GAGTAGAFL---LEPSSGELRTAAALDREQCPSYTFSVSA----VDGA- 1935
Query: 350 LRRGPFKDVASVRVAVQDAPE-PPAFTQAAYHLTVPEN----KAPGTLVGQISAADLDSP 404
GP SV + V+D + P F + L +P P + + A D D+
Sbjct: 1936 -AAGPLSTTVSVTITVRDVNDHAPTFPTSPLRLRLPRPGPSFSTPTLALATLRAEDRDAG 1994
Query: 405 A-SPIRYSILPHSDPERCFSIQPEEGTIHTA------APLDREARAWHNLTVLATELGWS 457
A + I Y + P ++ G I A P DR L ++AT+LG
Sbjct: 1995 ANASILYRLA--GTPPPGTTVDSYTGEIRVARSPVALGPRDRV------LFIVATDLG-- 2044
Query: 458 WGPERGWVPLLVA-------------EWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVA 504
P R +++ S+ A + +P G+ + P+ A + +
Sbjct: 2045 -RPARSATGVIIVGLQGEAERGPRFPRASSEATIRENAPPGTPIVSPRAVHAGGTNGPIT 2103
Query: 505 IQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQV---IRALDRDEVGNSSHVSFQGPLGPD 561
L N+ +P + +A G +V +R + + E G + +
Sbjct: 2104 YSILSGNEKGTFSIQPSTGAITVRSAEGLDFEVSPRLRLVLQAESGGAFAFTV------- 2156
Query: 562 ANFTVQDNRDGSASLLLPSRPA-----PPRHAPYLVPIELWDWGQPALSSTATVTVSVCR 616
T+QD D + L P A P P L+ +E D Q S ++ S+
Sbjct: 2157 LTLTLQDANDNAPRFLRPHYVAFLPESRPLEGP-LLQVEADDLDQ---GSGGQISYSLAA 2212
Query: 617 CQP 619
QP
Sbjct: 2213 SQP 2215
Score = 107 bits (266), Expect = 6e-23
Identities = 138/554 (24%), Positives = 214/554 (38%), Gaps = 92/554 (16%)
Query: 94 IDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIK-VQDINDNPPIFPL 152
+D TG I V +S VL A D RP + II +Q + P FP
Sbjct: 2013 VDSYTGEIRVARSPVALGPRDRVLFIVATDLG--RPARSATGVIIVGLQGEAERGPRFPR 2070
Query: 153 GPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLP--FFSVDPQTGVVRT 210
AT+ E + GT ++ A A G + + Y++L G FS+ P TG +
Sbjct: 2071 ASSEATIRENAPPGTPIVSPRAVHAG----GTNGPITYSILSGNEKGTFSIQPSTGAITV 2126
Query: 211 -AIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVV 269
+ +D E +V+QA+ GG T +T+TL D NDN P+F + Y +
Sbjct: 2127 RSAEGLDFEVSPRLRLVLQAES-----GGAFAFTVLTLTLQDANDNAPRFLRPHYVAFLP 2181
Query: 270 ETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFE 329
E+ + ++ A D D G ++YS+ + + + G +T LD E
Sbjct: 2182 ESRPLEGPLLQVEADDLDQGSGGQISYSLAASQPARGLF---HVDPTTGTITTTAILDRE 2238
Query: 330 SQRSYSFRVEATNTLIDPAYLRRGP-FKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKA 388
+ A L+ A R P A++ V V D + + L V E+
Sbjct: 2239 --------IWAETRLVLMATDRGSPALVGSATLTVMVIDTNDNRPTIPQPWELRVSEDAL 2290
Query: 389 PGTLVGQISAADLDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLT 448
G+ + Q++ D+DS P+ + +L S P+ FS+ G + PLD E + L
Sbjct: 2291 LGSEIAQVTGNDVDS--GPVLWYVLSPSGPQDPFSVGRYGGRVSLTGPLDFEQCDRYQLQ 2348
Query: 449 VLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTL 508
+LA + GP G R + +
Sbjct: 2349 LLAHD-----GPHEG------------------------------------RANLTVLVE 2367
Query: 509 DENDNAPQLAEP-YDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQGPLGPDANFTVQ 567
D NDNAP ++ Y + + PG I + A DRD G + H+S+ P F+V
Sbjct: 2368 DVNDNAPAFSQSLYQVMLLEHTPPGSAILSVSATDRDS-GANGHISYH-LASPADGFSVD 2425
Query: 568 DNR----------------DGSASLLLPSRP--APPRHAPYLVPIELWDWGQPALSSTAT 609
N G+ ++L +R AP R A V ++L D A S T +
Sbjct: 2426 PNNGTLFTIVGTVALGHDGSGAVDVVLEARDHGAPGRAARATVHVQLQDQNDHAPSFTLS 2485
Query: 610 -VTVSVCRCQPDGS 622
V+V P GS
Sbjct: 2486 HYRVAVTEDLPPGS 2499
Score = 103 bits (257), Expect = 6e-22
Identities = 80/251 (31%), Positives = 127/251 (50%), Gaps = 22/251 (8%)
Query: 60 PEPVLIGK--LH---SDVDRG-EGRTKYLLTGEGAGTVFVIDEATGNIHVTKSLDREEKA 113
PE +G LH SD D G G ++ ++ +F +DE++G + + +LD E +A
Sbjct: 2612 PEDTPVGAELLHVEASDADPGPHGLVRFTVSSGDPSGLFELDESSGTLRLAHALDCETQA 2671
Query: 114 QYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVT 173
++ L+ QA D A P I+VQD+ND+ P FPL +V E GT V +
Sbjct: 2672 RHQLVVQAADPAGAHFALAP--VTIEVQDVNDHGPAFPLNLLSTSVAENQPPGTLVTTLH 2729
Query: 174 AHDADDPSYGNSAKLVYTVL------DGLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVI 227
A D D ++G +L Y++L +G F+++ TG +R +P D E E F +++
Sbjct: 2730 AIDGDAGAFG---RLRYSLLEAGPGPEGREAFALNSSTGELRARVP-FDYEHTESFRLLV 2785
Query: 228 QAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPD 287
A D G LS S TV+V ++ ++ P F + F V E A G +G ++A D D
Sbjct: 2786 GAAD----AGNLSASVTVSVLVTGEDEYDPVFLAPAFHFQVPEGARRGHSLGHVQATDED 2841
Query: 288 LGDNALMAYSI 298
G + L+ YS+
Sbjct: 2842 GGADGLVLYSL 2852
Score = 38.1 bits (87), Expect = 0.033
Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 3/86 (3%)
Query: 371 PPAFTQA-AYHLTVPENKAPGTLVGQISAADLDSPASPIRYSILPH--SDPERCFSIQPE 427
P A+ QA + L + E + GTL+G ISA A+P+ Y I S +I
Sbjct: 38 PGAWGQAGSLDLQIDEEQPAGTLIGDISAGLPAGTAAPLMYFISAQEGSGVGTDLAIDEH 97
Query: 428 EGTIHTAAPLDREARAWHNLTVLATE 453
G + TA LDRE R + T + +
Sbjct: 98 SGVVRTARVLDREQRDRYRFTAVTPD 123
>gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo
sapiens]
Length = 847
Score = 184 bits (466), Expect = 4e-46
Identities = 176/672 (26%), Positives = 301/672 (44%), Gaps = 70/672 (10%)
Query: 39 LLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAG----TVFVI 94
L R +R W ++E GP P+ + ++ SD + Y + G G +F +
Sbjct: 130 LRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNY-TIYYSIRGPGVDQEPRNLFYV 188
Query: 95 DEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGP 154
+ TGN++ T+ +DRE+ + ++A A P E P IIK++D NDN PIF
Sbjct: 189 ERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTP-ELPLPLIIKIEDENDNYPIFTEET 247
Query: 155 YHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLP----FFSVDPQTGVVRT 210
Y T+ E VGT+V QV A D D+P ++ +L Y+++ +P FS+ P TGV+ T
Sbjct: 248 YTFTIFENCRVGTTVGQVCATDKDEPDTMHT-RLKYSIIGQVPPSPTLFSMHPTTGVITT 306
Query: 211 AIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVE 270
+DRE +++ + I+ +DM G GL ++T + + DVND+ P F ++ Y SV E
Sbjct: 307 TSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVTSVEE 366
Query: 271 TAGPGTLVGRLRAQDPDLGDNA--LMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDF 328
++ R+ +D DL + A Y+IL G + F I TD + +G+L V KPL++
Sbjct: 367 NTVDVEIL-RVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPLNY 425
Query: 329 ESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKA 388
E ++ ++ N A+V V V+D E P + + EN
Sbjct: 426 EEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKENAE 485
Query: 389 PGTLVGQISAADLDS-PASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREA----RA 443
GT A D ++ +S IRY L +DP +I G+I LDREA
Sbjct: 486 VGTTSNGYKAYDPETRSSSGIRYKKL--TDPTGWVTIDENTGSIKVFRSLDREAETIKNG 543
Query: 444 WHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQV 503
+N+TVLA++ G + L ++P P + + P SSA+ V
Sbjct: 544 IYNITVLASDQGGRTCTGTLGIILQDVNDNSPFIPKKTVIICK----PTMSSAEIVAVDP 599
Query: 504 AIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQGPLGPDAN 563
DE + P P+D + S + Q + ++A++ ++ +S+Q
Sbjct: 600 -----DEPIHGP----PFDFSLESSTSEVQRMWRLKAIN----DTAARLSYQN------- 639
Query: 564 FTVQDNRDGSASLLLPSRPAPPRHAPYLVPIELWDWGQPALSSTATVTVSVCRCQPDGSV 623
P Y+VPI + D + +SS ++ V++C C +
Sbjct: 640 --------------------DPPFGSYVVPITVRD--RLGMSSVTSLDVTLCDCITEND- 676
Query: 624 ASCWPEAHLSAAGLSTG--ALLAIITCVGALLALVVLFVALRRQKQEALMVLEEEDVREN 681
+ + + G+ G A+LAI+ + L ++ V + V+ ++ ++N
Sbjct: 677 CTHRVDPRIGGGGVQLGKWAILAILLGIALLFCILFTLVCGASGTSKQPKVIPDDLAQQN 736
Query: 682 IITYDDEGGGEE 693
+I + E G++
Sbjct: 737 LIVSNTEAPGDD 748
>gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo
sapiens]
Length = 901
Score = 184 bits (466), Expect = 4e-46
Identities = 176/672 (26%), Positives = 301/672 (44%), Gaps = 70/672 (10%)
Query: 39 LLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAG----TVFVI 94
L R +R W ++E GP P+ + ++ SD + Y + G G +F +
Sbjct: 130 LRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNY-TIYYSIRGPGVDQEPRNLFYV 188
Query: 95 DEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGP 154
+ TGN++ T+ +DRE+ + ++A A P E P IIK++D NDN PIF
Sbjct: 189 ERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTP-ELPLPLIIKIEDENDNYPIFTEET 247
Query: 155 YHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLP----FFSVDPQTGVVRT 210
Y T+ E VGT+V QV A D D+P ++ +L Y+++ +P FS+ P TGV+ T
Sbjct: 248 YTFTIFENCRVGTTVGQVCATDKDEPDTMHT-RLKYSIIGQVPPSPTLFSMHPTTGVITT 306
Query: 211 AIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVE 270
+DRE +++ + I+ +DM G GL ++T + + DVND+ P F ++ Y SV E
Sbjct: 307 TSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVTSVEE 366
Query: 271 TAGPGTLVGRLRAQDPDLGDNA--LMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDF 328
++ R+ +D DL + A Y+IL G + F I TD + +G+L V KPL++
Sbjct: 367 NTVDVEIL-RVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPLNY 425
Query: 329 ESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKA 388
E ++ ++ N A+V V V+D E P + + EN
Sbjct: 426 EEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKENAE 485
Query: 389 PGTLVGQISAADLDS-PASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREA----RA 443
GT A D ++ +S IRY L +DP +I G+I LDREA
Sbjct: 486 VGTTSNGYKAYDPETRSSSGIRYKKL--TDPTGWVTIDENTGSIKVFRSLDREAETIKNG 543
Query: 444 WHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQV 503
+N+TVLA++ G + L ++P P + + P SSA+ V
Sbjct: 544 IYNITVLASDQGGRTCTGTLGIILQDVNDNSPFIPKKTVIICK----PTMSSAEIVAVDP 599
Query: 504 AIQTLDENDNAPQLAEPYDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQGPLGPDAN 563
DE + P P+D + S + Q + ++A++ ++ +S+Q
Sbjct: 600 -----DEPIHGP----PFDFSLESSTSEVQRMWRLKAIN----DTAARLSYQN------- 639
Query: 564 FTVQDNRDGSASLLLPSRPAPPRHAPYLVPIELWDWGQPALSSTATVTVSVCRCQPDGSV 623
P Y+VPI + D + +SS ++ V++C C +
Sbjct: 640 --------------------DPPFGSYVVPITVRD--RLGMSSVTSLDVTLCDCITEND- 676
Query: 624 ASCWPEAHLSAAGLSTG--ALLAIITCVGALLALVVLFVALRRQKQEALMVLEEEDVREN 681
+ + + G+ G A+LAI+ + L ++ V + V+ ++ ++N
Sbjct: 677 CTHRVDPRIGGGGVQLGKWAILAILLGIALLFCILFTLVCGASGTSKQPKVIPDDLAQQN 736
Query: 682 IITYDDEGGGEE 693
+I + E G++
Sbjct: 737 LIVSNTEAPGDD 748
Score = 37.7 bits (86), Expect = 0.043
Identities = 23/49 (46%), Positives = 25/49 (51%), Gaps = 4/49 (8%)
Query: 761 DSVQVYGYEGRGSSCGSLSSLGSGSEAGGAPGPAEPLDDWGPLFRTLAE 809
D V Y YEGRGS GS+ E G E LD+ P FRTLAE
Sbjct: 852 DYVLTYNYEGRGSVAGSVGCCSERQEEDG----LEFLDNLEPKFRTLAE 896
>gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]
Length = 4588
Score = 182 bits (463), Expect = 8e-46
Identities = 169/555 (30%), Positives = 249/555 (44%), Gaps = 71/555 (12%)
Query: 70 SDVDRG-EGRTKYLLTGEGAGTVFVIDEATGNIHVTKSLDREEKAQYVLLAQAVD----- 123
+D+D G G+ Y ++G + F+ID TG + + LDRE +Y L D
Sbjct: 742 TDLDTGFNGKLVYAVSGGNEDSCFMIDMETGMLKILSPLDRETTDKYTLNITVYDLGIPQ 801
Query: 124 RASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYG 183
+A+ R L + V D NDNPP F Y V E V + +IQV A D D G
Sbjct: 802 KAAWRLLH------VVVVDANDNPPEFLQESYFVEVSEDKEVHSEIIQVEATDKD---LG 852
Query: 184 NSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGST 243
+ + Y+++ FS+D TGVV A P +DRE Q E + I+A+D L +
Sbjct: 853 PNGHVTYSIVTDTDTFSIDSVTGVVNIARP-LDRELQHEHSLKIEARDQAREEPQLFSTV 911
Query: 244 TVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILD-GE 302
V V+L DVNDNPP F Y+ V E GT++ L A DPDLG + + YS+LD GE
Sbjct: 912 VVKVSLEDVNDNPPTFIPPNYRVKVREDLPEGTVIMWLEAHDPDLGQSGQVRYSLLDHGE 971
Query: 303 GSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVR 362
G + D+ G + + + LDFE ++ Y+ V A + P L + +V
Sbjct: 972 G------NFDVDKLSGAVRIVQQLDFEKKQVYNLTVRAKDK-GKPVSLSSTCYVEVEV-- 1022
Query: 363 VAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAADLDSPA-SPIRYSILPHSDPERC 421
V V + PP F+ TV E+ G+LV +SA D D+ IRYSI S
Sbjct: 1023 VDVNENLHPPVFSSFVEKGTVKEDAPVGSLVMTVSAHDEDARRDGEIRYSIRDGSG-VGV 1081
Query: 422 FSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQR 481
F I E G I T+ LDRE+ + + LTV AT ++G VPL
Sbjct: 1082 FKIGEETGVIETSDRLDRESTSHYWLTVFAT--------DQGVVPL-------------- 1119
Query: 482 SPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQLAEP-YDTFVCDSAAPGQLIQVIRA 540
+S +++ I+ D NDNAPQ +EP Y + +++ + I A
Sbjct: 1120 ----------------SSFIEIYIEVEDVNDNAPQTSEPVYYPEIMENSPKDVSVVQIEA 1163
Query: 541 LDRDEVGNSSHVSFQGPLGPDANFTVQDNRDGSASLLLPSRPAP-PRHAPYLVPIELWDW 599
D D N + P F++ + + SR + +++ + + D
Sbjct: 1164 FDPDSSSNDKLMYKITSGNPQGFFSIHPK---TGLITTTSRKLDREQQDEHILEVTVTDN 1220
Query: 600 GQPALSSTATVTVSV 614
G P S+ A V V +
Sbjct: 1221 GSPPKSTIARVIVKI 1235
Score = 172 bits (437), Expect = 9e-43
Identities = 168/572 (29%), Positives = 251/572 (43%), Gaps = 86/572 (15%)
Query: 60 PEPVLIGKL-----HSDVD-RGEGRTKYLLTGEGAGTVFVIDEATGNIHVTKSLDREEKA 113
PE VL GKL +D D R Y L G GA F ++ TG + + LDREE+A
Sbjct: 3033 PEDVLPGKLIMQISATDADIRSNAEITYTLLGSGAEK-FKLNPDTGELKTSTPLDREEQA 3091
Query: 114 QYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVT 173
Y LL +A D + ++ ++D+NDN P F PY TV E + GT + +V
Sbjct: 3092 VYHLLVRATDGGGRFC---QASIVLTLEDVNDNAPEFSADPYAITVFENTEPGTLLTRVQ 3148
Query: 174 AHDADDPSYGNSAKLVYTVLDGLPF-FSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDM 232
A DAD G + K++Y+++D FS++ +G+++ P +DRE Q + + ++A D
Sbjct: 3149 ATDADA---GLNRKILYSLIDSADGQFSINELSGIIQLEKP-LDRELQAVYTLSLKAVDQ 3204
Query: 233 GGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNA 292
G L+ + TV V++ D+NDNPP F Y +V E GT V ++ A D+ NA
Sbjct: 3205 GLPRR-LTATGTVIVSVLDINDNPPVFEYREYGATVSEDILVGTEVLQVYAASRDIEANA 3263
Query: 293 LMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRR 352
+ YSI+ G FSI + + G + + + LD+ES Y VEAT+
Sbjct: 3264 EITYSIISGNEHGKFSIDS----KTGAVFIIENLDYESSHEYYLTVEATDG-------GT 3312
Query: 353 GPFKDVASVRVAVQDAPE-PPAFTQAAYHLTVPENKAPGTLVGQISAADLDSPA-SPIRY 410
DVA+V V V D + P F+Q Y + E+ V + A D D P+ S I Y
Sbjct: 3313 PSLSDVATVNVNVTDINDNTPVFSQDTYTTVISEDAVLEQSVITVMADDADGPSNSHIHY 3372
Query: 411 SILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGPERGWVPLLVA 470
SI+ + F+I P G + LDRE + + LTV A++ G
Sbjct: 3373 SIIDGNQGSS-FTIDPVRGEVKVTKLLDRETISGYTLTVQASDNG--------------- 3416
Query: 471 EWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQLAEP-YDTFVCDSA 529
+PP+ + V I D NDNAP + Y + ++
Sbjct: 3417 ------SPPR-----------------VNTTTVNIDVSDVNDNAPVFSRGNYSVIIQENK 3453
Query: 530 APGQLIQVIRALDRDEVGNSSHVSFQGPLGPDANFTVQDNRDGSAS-------LLLPSRP 582
G + + D D N GP FT+ D A LL S
Sbjct: 3454 PVGFSVLQLVVTDEDSSHN----------GPPFFFTIVTGNDEKAFEVNPQGVLLTSSAI 3503
Query: 583 APPRHAPYLVPIELWDWGQPALSSTATVTVSV 614
YL+ +++ D G+P LSS + + V
Sbjct: 3504 KRKEKDHYLLQVKVADNGKPQLSSLTYIDIRV 3535
Score = 170 bits (430), Expect = 6e-42
Identities = 162/576 (28%), Positives = 253/576 (43%), Gaps = 87/576 (15%)
Query: 64 LIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEATGN--IHVTKSLDREEKAQYVLLAQA 121
++ +D + + Y +TG F ++ ++V K LDRE++ Y+L A
Sbjct: 2939 ILSTTDADSEEINRQVTYFITGGDPLGQFAVETIQNEWKVYVKKPLDREKRDNYLLTITA 2998
Query: 122 VDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDPS 181
D + +KV D NDN P+ Y T+PE G ++Q++A DAD S
Sbjct: 2999 TDGT----FSSKAIVEVKVLDANDNSPVCEKTLYSDTIPEDVLPGKLIMQISATDADIRS 3054
Query: 182 YGNSAKLVYTVL-DGLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLS 240
+A++ YT+L G F ++P TG ++T+ P +DRE Q + ++++A D GG S
Sbjct: 3055 ---NAEITYTLLGSGAEKFKLNPDTGELKTSTP-LDREEQAVYHLLVRATDGGGRFCQAS 3110
Query: 241 GSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILD 300
+ +TL DVNDN P+F Y +V E PGTL+ R++A D D G N + YS++D
Sbjct: 3111 ----IVLTLEDVNDNAPEFSADPYAITVFENTEPGTLLTRVQATDADAGLNRKILYSLID 3166
Query: 301 GEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVAS 360
+ FSI+ G++ + KPLD E Q Y+ ++A +D RR +
Sbjct: 3167 SADGQ-FSINE----LSGIIQLEKPLDRELQAVYTLSLKA----VDQGLPRR--LTATGT 3215
Query: 361 VRVAVQDAPE-PPAFTQAAYHLTVPENKAPGTLVGQISAADLDSPA-SPIRYSILPHSDP 418
V V+V D + PP F Y TV E+ GT V Q+ AA D A + I YSI+ ++
Sbjct: 3216 VIVSVLDINDNPPVFEYREYGATVSEDILVGTEVLQVYAASRDIEANAEITYSIISGNEH 3275
Query: 419 ERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAP 478
+ FSI + G + LD E+ + LTV AT+ G
Sbjct: 3276 GK-FSIDSKTGAVFIIENLDYESSHEYYLTVEATDGG----------------------T 3312
Query: 479 PQRSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQLA-EPYDTFVCDSAAPGQLIQV 537
P S V + V + D NDN P + + Y T + + A Q +
Sbjct: 3313 PSLSDVAT----------------VNVNVTDINDNTPVFSQDTYTTVISEDAVLEQSVIT 3356
Query: 538 IRALDRDEVGNSSHVSFQGPLGPDANFTVQDNRDGSASLLLPSRPA--------PPRHAP 589
+ A D D GP ++++ D GS+ + P R +
Sbjct: 3357 VMADDAD-----------GPSNSHIHYSIIDGNQGSSFTIDPVRGEVKVTKLLDRETISG 3405
Query: 590 YLVPIELWDWGQPALSSTATVTVSVCRCQPDGSVAS 625
Y + ++ D G P +T TV + V + V S
Sbjct: 3406 YTLTVQASDNGSPPRVNTTTVNIDVSDVNDNAPVFS 3441
Score = 163 bits (412), Expect = 7e-40
Identities = 130/405 (32%), Positives = 197/405 (48%), Gaps = 24/405 (5%)
Query: 56 EYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEATGNIHVTKSLDREEKAQY 115
E P +L +D D G R + A F I+E +G I + K LDRE +A Y
Sbjct: 3136 ENTEPGTLLTRVQATDADAGLNRKILYSLIDSADGQFSINELSGIIQLEKPLDRELQAVY 3195
Query: 116 VLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAH 175
L +AVD+ R L I+ V DINDNPP+F Y ATV E VGT V+QV A
Sbjct: 3196 TLSLKAVDQGLPRRLTATGTVIVSVLDINDNPPVFEYREYGATVSEDILVGTEVLQVYAA 3255
Query: 176 DADDPSYGNSAKLVYTVLDGLPF--FSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMG 233
D + +A++ Y+++ G FS+D +TG V I N+D E+ E+ + ++A D
Sbjct: 3256 SRDIEA---NAEITYSIISGNEHGKFSIDSKTGAV-FIIENLDYESSHEYYLTVEATD-- 3309
Query: 234 GHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNAL 293
G LS TV V ++D+NDN P F Q Y + E A V + A D D N+
Sbjct: 3310 GGTPSLSDVATVNVNVTDINDNTPVFSQDTYTTVISEDAVLEQSVITVMADDADGPSNSH 3369
Query: 294 MAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRG 353
+ YSI+DG +F+I G + V K LD E+ Y+ V+A++ P
Sbjct: 3370 IHYSIIDGNQGSSFTIDP----VRGEVKVTKLLDRETISGYTLTVQASDNGSPPRV---- 3421
Query: 354 PFKDVASVRVAVQDAPE-PPAFTQAAYHLTVPENKAPGTLVGQISAADLDSP--ASPIRY 410
+ +V + V D + P F++ Y + + ENK G V Q+ D DS P +
Sbjct: 3422 ---NTTTVNIDVSDVNDNAPVFSRGNYSVIIQENKPVGFSVLQLVVTDEDSSHNGPPFFF 3478
Query: 411 SILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELG 455
+I+ +D E+ F + P +G + T++ + R+ + + L V + G
Sbjct: 3479 TIVTGND-EKAFEVNP-QGVLLTSSAIKRKEKDHYLLQVKVADNG 3521
Score = 162 bits (411), Expect = 9e-40
Identities = 161/571 (28%), Positives = 245/571 (42%), Gaps = 70/571 (12%)
Query: 52 FVIEEYAGPEPVLIGKLHSDVDRG-EGRTKYLLTGEGAGTV---FVIDEATGNIHVTKSL 107
F++E G V+ + SD D G G+ Y L + V F I+ TG I K L
Sbjct: 2817 FIVENLPGGSRVIQIRA-SDADSGTNGQVMYSLDQSQSVEVIESFAINMETGWITTLKEL 2875
Query: 108 DREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGT 167
D E++ Y + A D L + + V D+ND+PP F Y TV E G
Sbjct: 2876 DHEKRDNYQIKVVASDHGEKIQLSSTAIVDVTVTDVNDSPPRFTAEIYKGTVSEDDPQGG 2935
Query: 168 SVIQVTAHDADDPSYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPN-MDRETQEEFLVV 226
+ ++ DAD T D L F+V+ + + +DRE ++ +L+
Sbjct: 2936 VIAILSTTDADSEEINRQVTYFITGGDPLGQFAVETIQNEWKVYVKKPLDREKRDNYLLT 2995
Query: 227 IQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDP 286
I A D G S V V + D NDN P ++LY ++ E PG L+ ++ A D
Sbjct: 2996 ITATD-----GTFSSKAIVEVKVLDANDNSPVCEKTLYSDTIPEDVLPGKLIMQISATDA 3050
Query: 287 DLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLID 346
D+ NA + Y++L G G+E F ++ D G L PLD E Q Y V AT+
Sbjct: 3051 DIRSNAEITYTLL-GSGAEKFKLNPD----TGELKTSTPLDREEQAVYHLLVRATD---- 3101
Query: 347 PAYLRRGPFKDVASVRVAVQDAPE-PPAFTQAAYHLTVPENKAPGTLVGQISAADLDSPA 405
G F AS+ + ++D + P F+ Y +TV EN PGTL+ ++ A D D+
Sbjct: 3102 ----GGGRFCQ-ASIVLTLEDVNDNAPEFSADPYAITVFENTEPGTLLTRVQATDADAGL 3156
Query: 406 S-PIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGPERGW 464
+ I YS++ +D + FSI G I PLDRE +A + L++ A +
Sbjct: 3157 NRKILYSLIDSADGQ--FSINELSGIIQLEKPLDRELQAVYTLSLKAVD----------- 3203
Query: 465 VPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQLA-EPYDT 523
G+P+ +A + V + LD NDN P Y
Sbjct: 3204 -----------------------QGLPRRLTATGT---VIVSVLDINDNPPVFEYREYGA 3237
Query: 524 FVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQGPLGPDANFTVQDNRDGSASLLLPSRPA 583
V + G + + A RD N + +++ G + D++ G A ++ +
Sbjct: 3238 TVSEDILVGTEVLQVYAASRDIEAN-AEITYSIISGNEHGKFSIDSKTG-AVFIIENLDY 3295
Query: 584 PPRHAPYLVPIELWDWGQPALSSTATVTVSV 614
H YL +E D G P+LS ATV V+V
Sbjct: 3296 ESSHEYYLT-VEATDGGTPSLSDVATVNVNV 3325
Score = 150 bits (378), Expect = 6e-36
Identities = 146/518 (28%), Positives = 219/518 (42%), Gaps = 64/518 (12%)
Query: 37 PALLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEG-RTKYLLTGEGAGTVFVID 95
P + + V+ + F E A V +H + EG + Y +T + F I+
Sbjct: 2171 PITVMNKAMPVFEKPFYSAEIAESIQVHSPVVHVQANSPEGLKVFYSITDGDPFSQFTIN 2230
Query: 96 EATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPY 155
TG I+V LD E Y L +A D + E + I V DINDNPP+F Y
Sbjct: 2231 FNTGVINVIAPLDFEAHPAYKLSIRATDSLTGAHAEVFVDII--VDDINDNPPVFAQQSY 2288
Query: 156 HATVPEMSNVGTSVIQVTAHDAD-DPSYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPN 214
T+ E S +GTSV+QV A D+D +P+ G S ++ F VD TG++ + +
Sbjct: 2289 AVTLSEASVIGTSVVQVRATDSDSEPNRGISYQMFGNHSKSHDHFHVDSSTGLI-SLLRT 2347
Query: 215 MDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGP 274
+D E + + ++A D G M LS VTV ++D+NDNPP F Q +Y+ + E A
Sbjct: 2348 LDYEQSRQHTIFVRAVD--GGMPTLSSDVIVTVDVTDLNDNPPLFEQQIYEARISEHAPH 2405
Query: 275 GTLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSY 334
G V ++A D D D + YSIL G + F I + G++T+ + Y
Sbjct: 2406 GHFVTCVKAYDADSSDIDKLQYSILSGNDHKHFVIDS----ATGIITLSNLHRHALKPFY 2461
Query: 335 SFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAP-EPPAFTQAAYHLTVPENKAPGTLV 393
S + ++ G F+ V V V PAF Q Y + + EN TLV
Sbjct: 2462 SLNLSVSD----------GVFRSSTQVHVTVIGGNLHSPAFLQNEYEVELAENAPLHTLV 2511
Query: 394 GQISAADLDSPA-SPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLAT 452
++ D DS + Y I+ +R + E G I T LDRE A ++V
Sbjct: 2512 MEVKTTDGDSGIYGHVTYHIVNDFAKDRFYI--NERGQIFTLEKLDRETPAEKVISVRL- 2568
Query: 453 ELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTLDEND 512
+ +D+ + + V + D+ND
Sbjct: 2569 -------------------------------------MAKDAGGKVAFCTVNVILTDDND 2591
Query: 513 NAPQL-AEPYDTFVCDSAAPGQLIQVIRALDRDEVGNS 549
NAPQ A Y+ + SAA G + + A D DE N+
Sbjct: 2592 NAPQFRATKYEVNIGSSAAKGTSVVKVLASDADEGSNA 2629
Score = 144 bits (363), Expect = 3e-34
Identities = 130/481 (27%), Positives = 201/481 (41%), Gaps = 82/481 (17%)
Query: 83 LTGEGAGTVFVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQD 142
+TG + F +D+ TG I V K LD E+K+ Y L +A D + ++ IKV D
Sbjct: 1393 ITGGNYDSHFDVDKGTGTIIVAKPLDAEQKSNYNLTVEATDGTTTIL----TQVFIKVID 1448
Query: 143 INDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDG-----LP 197
ND+ P F Y +PE + T ++Q++A D D+ + KL+YT+ L
Sbjct: 1449 TNDHRPQFSTSKYEVVIPEDTAPETEILQISAVDQDEKN-----KLIYTLQSSRDPLSLK 1503
Query: 198 FFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPP 257
F +DP TG + T+ +D E + + + +D + + V +SD ND+ P
Sbjct: 1504 KFRLDPATGSLYTS-EKLDHEAVHQHTLTVMVRDQDVPVK--RNFARIVVNVSDTNDHAP 1560
Query: 258 KFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRD 317
F S Y+ V E+A G++V ++ A D D G NA + YSI G +F I L
Sbjct: 1561 WFTASSYKGRVYESAAVGSVVLQVTALDKDKGKNAEVLYSIESGNIGNSFMIDPVL---- 1616
Query: 318 GLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPE-PPAFTQ 376
G + K LD +Q Y V+AT+ P ++ SVR+ V A P FT
Sbjct: 1617 GSIKTAKELDRSNQAEYDLMVKATDK-------GSPPMSEITSVRIFVTIADNASPKFTS 1669
Query: 377 AAYHLTVPENKAPGTLVGQISAADLDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAP 436
Y + + E + G+ VG ++A S I+ + F I P GTI T
Sbjct: 1670 KEYSVELSETVSIGSFVGMVTAHSQSSVVYEIK-----DGNTGDAFDINPHSGTIITQKA 1724
Query: 437 LDREARAWHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSA 496
LD E + L + T + +
Sbjct: 1725 LDFETLPIYTLIIQGTNM----------------------------------------AG 1744
Query: 497 QASRVQVAIQTLDENDNAPQLAE-PYDTFVCDSAAPGQLI-------QVIRALDRDEVGN 548
++ V + DENDNAP + Y + +SA+ ++ VIRA D D+ N
Sbjct: 1745 LSTNTTVLVHLQDENDNAPVFMQAEYTGLISESASINSVVLTDRNVPLVIRAADADKDSN 1804
Query: 549 S 549
+
Sbjct: 1805 A 1805
Score = 140 bits (354), Expect = 4e-33
Identities = 156/588 (26%), Positives = 240/588 (40%), Gaps = 105/588 (17%)
Query: 52 FVIEEYAGP--EPVLIGKLHSDVD-RGEGRTKYLLTGEGAGTVFVIDEATGNIHVTKSLD 108
F +EY+ E V IG V + Y + G F I+ +G I K+LD
Sbjct: 1667 FTSKEYSVELSETVSIGSFVGMVTAHSQSSVVYEIKDGNTGDAFDINPHSGTIITQKALD 1726
Query: 109 REEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTS 168
E Y L+ Q + A L + ++ +QD NDN P+F Y + E +++ +
Sbjct: 1727 FETLPIYTLIIQGTNMAG---LSTNTTVLVHLQDENDNAPVFMQAEYTGLISESASINSV 1783
Query: 169 VIQ-------VTAHDADDPSYGNSAKLVYTVLDGL--PFFSVDPQTGVVRTAIPNMDRET 219
V+ + A DAD S +A LVY +++ +F++D TG + T + ++D E
Sbjct: 1784 VLTDRNVPLVIRAADADKDS---NALLVYHIVEPSVHTYFAIDSSTGAIHTVL-SLDYEE 1839
Query: 220 QEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVG 279
F +Q DMG + VTV + D+ND PP F + LY+ S++ G V
Sbjct: 1840 TSIFHFTVQVHDMGTPRLFAEYAANVTVHVIDINDCPPVFAKPLYEASLLLPTYKGVKVI 1899
Query: 280 RLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVE 339
+ A D D + + YSI +G E FS + + G LTV+ S+ Y V
Sbjct: 1900 TVNATDADSSAFSQLIYSITEGNIGEKFS----MDYKTGALTVQNTTQLRSR--YELTVR 1953
Query: 340 ATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPP-AFTQAAYHLTVPENKAPGTLVGQISA 398
A++ G F + SV++ V+++ E FTQ Y V EN + I+A
Sbjct: 1954 ASD----------GRFAGLTSVKINVKESKESHLKFTQDVYSAVVKENSTEAETLAVITA 2003
Query: 399 ADLDSPAS-PIRYSILPHSDPERCFSIQPEEGTIH-TAAPLDREARAWHNLTVLATELGW 456
+ +P + P+ Y IL +P+R F I G + T P DRE + ++ V TE
Sbjct: 2004 --IGNPINEPLFYHIL---NPDRRFKISRTSGVLSTTGTPFDREQQEAFDVVVEVTE--- 2055
Query: 457 SWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQ 516
+ + + V V + D+NDNAP
Sbjct: 2056 -----------------------------------EHKPSAVAHVVVKVIVEDQNDNAPV 2080
Query: 517 LAE-PYDTFVCDSAAPGQLIQVIRALDRDEVGNSS--------HVSFQ-GPLGPDANFTV 566
PY V G +I+ + A+DRD N H FQ GPLG + +
Sbjct: 2081 FVNLPYYAVVKVDTEVGHVIRYVTAVDRDSGRNGEVHYYLKEHHEHFQIGPLG-EISLKK 2139
Query: 567 QDNRDGSASLLLPSRPAPPRHAPYLVPIELWDWGQPALSSTATVTVSV 614
Q D + YLV + D G PA S+ V ++V
Sbjct: 2140 QFELD-------------TLNKEYLVTVVAKDGGNPAFSAEVIVPITV 2174
Score = 130 bits (326), Expect = 6e-30
Identities = 122/465 (26%), Positives = 198/465 (42%), Gaps = 74/465 (15%)
Query: 92 FVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPP-SEFIIKVQDINDNPPIF 150
F +D ATG+++ ++ LD E Q+ L D+ + P++ + ++ V D ND+ P F
Sbjct: 1505 FRLDPATGSLYTSEKLDHEAVHQHTLTVMVRDQ--DVPVKRNFARIVVNVSDTNDHAPWF 1562
Query: 151 PLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGL--PFFSVDPQTGVV 208
Y V E + VG+ V+QVTA D D G +A+++Y++ G F +DP G +
Sbjct: 1563 TASSYKGRVYESAAVGSVVLQVTALDKDK---GKNAEVLYSIESGNIGNSFMIDPVLGSI 1619
Query: 209 RTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSV 268
+TA +DR Q E+ ++++A D G S + VT++D + PKF Y +
Sbjct: 1620 KTA-KELDRSNQAEYDLMVKATDKGSPPMSEITSVRIFVTIAD--NASPKFTSKEYSVEL 1676
Query: 269 VETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDF 328
ET G+ VG + A + + Y I DG +AF D+ G + +K LDF
Sbjct: 1677 SETVSIGSFVGMVTAHS-----QSSVVYEIKDGNTGDAF----DINPHSGTIITQKALDF 1727
Query: 329 ESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPE-PPAFTQAAYHLTVPENK 387
E+ Y+ ++ TN +V V +QD + P F QA Y + E+
Sbjct: 1728 ETLPIYTLIIQGTNM---------AGLSTNTTVLVHLQDENDNAPVFMQAEYTGLISESA 1778
Query: 388 APGTLVGQ-------ISAADLDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDRE 440
+ ++V I AAD D ++ + + F+I G IHT LD E
Sbjct: 1779 SINSVVLTDRNVPLVIRAADADKDSNALLVYHIVEPSVHTYFAIDSSTGAIHTVLSLDYE 1838
Query: 441 ARAWHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASR 500
+ + TV ++G P L AE++A
Sbjct: 1839 ETSIFHFTVQVHDMG---------TPRLFAEYAA-------------------------- 1863
Query: 501 VQVAIQTLDENDNAPQLAEP-YDTFVCDSAAPGQLIQVIRALDRD 544
V + +D ND P A+P Y+ + G + + A D D
Sbjct: 1864 -NVTVHVIDINDCPPVFAKPLYEASLLLPTYKGVKVITVNATDAD 1907
Score = 127 bits (319), Expect = 4e-29
Identities = 120/435 (27%), Positives = 199/435 (45%), Gaps = 40/435 (9%)
Query: 60 PEPVLIGKLHS-DVDRGE-GRTKYLLTGEGAGTVFVIDEATGNIHVTKSLDREEKAQYVL 117
PE +I L + D D G+ G+ +Y L G G F +D+ +G + + + LD E+K Y L
Sbjct: 941 PEGTVIMWLEAHDPDLGQSGQVRYSLLDHGEGN-FDVDKLSGAVRIVQQLDFEKKQVYNL 999
Query: 118 LAQAVDRASNRPLEPPSEFIIKVQDINDN--PPIFPLGPYHATVPEMSNVGTSVIQVTAH 175
+A D+ L ++V D+N+N PP+F TV E + VG+ V+ V+AH
Sbjct: 1000 TVRAKDKGKPVSLSSTCYVEVEVVDVNENLHPPVFSSFVEKGTVKEDAPVGSLVMTVSAH 1059
Query: 176 DADDPSYGNSAKLVYTVLDG--LPFFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMG 233
D D G ++ Y++ DG + F + +TGV+ T+ +DRE+ + + + A D G
Sbjct: 1060 DEDARRDG---EIRYSIRDGSGVGVFKIGEETGVIETS-DRLDRESTSHYWLTVFATDQG 1115
Query: 234 GHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNAL 293
+ LS + + + DVNDN P+ + +Y ++E + V ++ A DPD N
Sbjct: 1116 --VVPLSSFIEIYIEVEDVNDNAPQTSEPVYYPEIMENSPKDVSVVQIEAFDPDSSSNDK 1173
Query: 294 MAYSILDGEGSEAFSISTDLQGRDGLL-TVRKPLDFESQRSYSFRVEATNTLIDPAYLRR 352
+ Y I G FSI + GL+ T + LD E Q + V T+
Sbjct: 1174 LMYKITSGNPQGFFSI----HPKTGLITTTSRKLDREQQDEHILEVTVTDN-------GS 1222
Query: 353 GPFKDVASVRVAVQDAPE-PPAFTQAAYHLTVPENKAPG--------TLVGQISAADLDS 403
P +A V V + D + P F Q Y + +PE + P L I+ +
Sbjct: 1223 PPKSTIARVIVKILDENDNKPQFLQKFYKIRLPEREKPDRERNARREPLYHVIATDKDEG 1282
Query: 404 PASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGPERG 463
P + I YSI ++ + F I+P+ G + ++ A + L++ A + G P++
Sbjct: 1283 PNAEISYSIEDGNEHGK-FFIEPKTGVV--SSKRFSAAGEYDILSIKAVDNG---RPQKS 1336
Query: 464 WVPLLVAEWSAPAAP 478
L EW + P
Sbjct: 1337 STTRLHIEWISKPKP 1351
Score = 123 bits (309), Expect = 6e-28
Identities = 137/549 (24%), Positives = 229/549 (41%), Gaps = 82/549 (14%)
Query: 81 YLLTGEGAGTVFVIDEATGNIHVT-KSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIK 139
Y +T F I TG I T + LDRE++ +++L D S P + I+K
Sbjct: 1176 YKITSGNPQGFFSIHPKTGLITTTSRKLDREQQDEHILEVTVTDNGSP-PKSTIARVIVK 1234
Query: 140 VQDINDNPPIFPLGPYHATVPEMSNVGTS-------VIQVTAHDADDPSYGNSAKLVYTV 192
+ D NDN P F Y +PE + V A D D+ G +A++ Y++
Sbjct: 1235 ILDENDNKPQFLQKFYKIRLPEREKPDRERNARREPLYHVIATDKDE---GPNAEISYSI 1291
Query: 193 LDGLPF--FSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVT-VTL 249
DG F ++P+TGVV + E ++ I+A D G + + ++
Sbjct: 1292 EDGNEHGKFFIEPKTGVVSS---KRFSAAGEYDILSIKAVDNGRPQKSSTTRLHIEWISK 1348
Query: 250 SDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSI 309
+ P F +S + F+V+E+ ++G + + P + + + I G F
Sbjct: 1349 PKPSLEPISFEESFFTFTVMESDPVAHMIGVISVEPPGIP----LWFDITGGNYDSHF-- 1402
Query: 310 STDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAP 369
D+ G + V KPLD E + +Y+ VEAT+ G + V + V D
Sbjct: 1403 --DVDKGTGTIIVAKPLDAEQKSNYNLTVEATD----------GTTTILTQVFIKVIDTN 1450
Query: 370 E-PPAFTQAAYHLTVPENKAPGTLVGQISAADLDSPASPIRYSILPHSDP--ERCFSIQP 426
+ P F+ + Y + +PE+ AP T + QISA D D + + Y++ DP + F + P
Sbjct: 1451 DHRPQFSTSKYEVVIPEDTAPETEILQISAVDQDE-KNKLIYTLQSSRDPLSLKKFRLDP 1509
Query: 427 EEGTIHTAAPLDREARAWHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGS 486
G+++T+ LD EA H LTV+ +
Sbjct: 1510 ATGSLYTSEKLDHEAVHQHTLTVMVRD--------------------------------- 1536
Query: 487 AVGIPQDSSAQASRVQVAIQTLDENDNAPQL-AEPYDTFVCDSAAPGQLIQVIRALDRDE 545
QD + + ++ + D ND+AP A Y V +SAA G ++ + ALD+D+
Sbjct: 1537 -----QDVPVKRNFARIVVNVSDTNDHAPWFTASSYKGRVYESAAVGSVVLQVTALDKDK 1591
Query: 546 VGNSSHVSFQGPLGPDANFTVQDNRDGSASLLLPSRPAPPRHAPYLVPIELWDWGQPALS 605
G ++ V + G N + D G S+ A Y + ++ D G P +S
Sbjct: 1592 -GKNAEVLYSIESGNIGNSFMIDPVLG--SIKTAKELDRSNQAEYDLMVKATDKGSPPMS 1648
Query: 606 STATVTVSV 614
+V + V
Sbjct: 1649 EITSVRIFV 1657
Score = 117 bits (292), Expect = 6e-26
Identities = 120/416 (28%), Positives = 188/416 (45%), Gaps = 46/416 (11%)
Query: 54 IEEYAGPEPVLIGKLHSDVDRGEG-RTKYLLTGEGAGTVFVIDEATGNIHVTKSLDREEK 112
+ E A V++ D D+G+ Y + G F+ID G+I K LDR +
Sbjct: 1571 VYESAAVGSVVLQVTALDKDKGKNAEVLYSIESGNIGNSFMIDPVLGSIKTAKELDRSNQ 1630
Query: 113 AQYVLLAQAVDRASNRPLEPPSEFIIKVQ---DINDN-PPIFPLGPYHATVPEMSNVGTS 168
A+Y L+ +A D+ S PP I V+ I DN P F Y + E ++G+
Sbjct: 1631 AEYDLMVKATDKGS-----PPMSEITSVRIFVTIADNASPKFTSKEYSVELSETVSIGSF 1685
Query: 169 VIQVTAHDADDPSYGNSAKLVYTVLDGL--PFFSVDPQTGVVRTAIPNMDRETQEEFLVV 226
V VTAH + + +VY + DG F ++P +G + T +D ET + ++
Sbjct: 1686 VGMVTAH--------SQSSVVYEIKDGNTGDAFDINPHSGTIITQ-KALDFETLPIYTLI 1736
Query: 227 IQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGR------ 280
IQ G +M GLS +TTV V L D NDN P F Q+ Y + E+A ++V
Sbjct: 1737 IQ----GTNMAGLSTNTTVLVHLQDENDNAPVFMQAEYTGLISESASINSVVLTDRNVPL 1792
Query: 281 -LRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVE 339
+RA D D NAL+ Y I++ F+I + G + LD+E + F V+
Sbjct: 1793 VIRAADADKDSNALLVYHIVEPSVHTYFAIDSS----TGAIHTVLSLDYEETSIFHFTVQ 1848
Query: 340 ATNTLIDPAYLRRGPFKDVASVRVAVQDAPE-PPAFTQAAYHLTVPENKAPGTLVGQISA 398
+ + + A+V V V D + PP F + Y ++ G V ++A
Sbjct: 1849 VHDMGTPRLFA-----EYAANVTVHVIDINDCPPVFAKPLYEASLLLPTYKGVKVITVNA 1903
Query: 399 ADLDSPA-SPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATE 453
D DS A S + YSI + E+ FS+ + G + + R+ + LTV A++
Sbjct: 1904 TDADSSAFSQLIYSITEGNIGEK-FSMDYKTGAL--TVQNTTQLRSRYELTVRASD 1956
Score = 117 bits (292), Expect = 6e-26
Identities = 103/383 (26%), Positives = 169/383 (44%), Gaps = 25/383 (6%)
Query: 59 GPEPVLIGKLHSDVDRGEGRTKYLLTGEGAGTVFVIDEATGNIHVTKSLDREEKAQYVLL 118
G E + + D++ T +++G G F ID TG + + ++LD E +Y L
Sbjct: 3246 GTEVLQVYAASRDIEANAEITYSIISGNEHGK-FSIDSKTGAVFIIENLDYESSHEYYLT 3304
Query: 119 AQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDAD 178
+A D L + + V DINDN P+F Y + E + + SVI V A DAD
Sbjct: 3305 VEATD-GGTPSLSDVATVNVNVTDINDNTPVFSQDTYTTVISEDAVLEQSVITVMADDAD 3363
Query: 179 DPSYGNSAKLVYTVLDGLP--FFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHM 236
PS ++ + Y+++DG F++DP G V+ +DRET + + +QA D G
Sbjct: 3364 GPS---NSHIHYSIIDGNQGSSFTIDPVRGEVKVT-KLLDRETISGYTLTVQASDNGSPP 3419
Query: 237 GGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNAL-MA 295
+TTV + +SDVNDN P F + Y + E G V +L D D N
Sbjct: 3420 R--VNTTTVNIDVSDVNDNAPVFSRGNYSVIIQENKPVGFSVLQLVVTDEDSSHNGPPFF 3477
Query: 296 YSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPF 355
++I+ G +AF ++ G+L + + + Y +V+ + L +
Sbjct: 3478 FTIVTGNDEKAFEVNPQ-----GVLLTSSAIKRKEKDHYLLQVKVADN--GKPQLSSLTY 3530
Query: 356 KDVASVRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAADLDSPASPIRYSILPH 415
D+ ++++ PPA +T + G ++G+I A D D + YS+ P
Sbjct: 3531 IDIR----VIEESIYPPAILPLEIFITSSGEEYSGGVIGKIHATDQD-VYDTLTYSLDPQ 3585
Query: 416 SDPERCFSIQPEEGTIHTAAPLD 438
D FS+ G + LD
Sbjct: 3586 MD--NLFSVSSTGGKLIAHKKLD 3606
Score = 113 bits (283), Expect = 6e-25
Identities = 124/489 (25%), Positives = 206/489 (42%), Gaps = 77/489 (15%)
Query: 70 SDVDRGEGRTKYLLTGEGAGTVFVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRP 129
SD+D+ +Y + FVID ATG I ++ +L R + L +V S+
Sbjct: 2420 SDIDK----LQYSILSGNDHKHFVIDSATGIITLS-NLHRHALKPFYSLNLSV---SDGV 2471
Query: 130 LEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLV 189
++ + V N + P F Y + E + + T V++V D D YG+ +
Sbjct: 2472 FRSSTQVHVTVIGGNLHSPAFLQNEYEVELAENAPLHTLVMEVKTTDGDSGIYGH---VT 2528
Query: 190 YTVLDGLPFFSVDP----QTGVVRTAIPNMDRETQEEFLVVIQ--AKDMGGHMGGLSGST 243
Y +++ F+ D + G + T + +DRET E ++ ++ AKD GG +
Sbjct: 2529 YHIVND---FAKDRFYINERGQIFT-LEKLDRETPAEKVISVRLMAKDAGGKVA----FC 2580
Query: 244 TVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEG 303
TV V L+D NDN P+F + Y+ ++ +A GT V ++ A D D G NA + Y+I
Sbjct: 2581 TVNVILTDDNDNAPQFRATKYEVNIGSSAAKGTSVVKVLASDADEGSNADITYAI--EAD 2638
Query: 304 SEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRV 363
SE+ + ++ G++T ++ L ++F V A + P K+ + V V
Sbjct: 2639 SESVKENLEINKLSGVITTKESLIGLENEFFTFFVRAVD--------NGSPSKE-SVVLV 2689
Query: 364 AVQDAP---EPPAFTQAAYHLTVPENKAPGTLVGQISAADLDSPASPIRYSILPHSDPER 420
V+ P + P F++ Y TV E+ GT + I A + + P S+ +
Sbjct: 2690 YVKILPPEMQLPKFSEPFYTFTVSEDVPIGTEIDLIRAEHSGTVLYSLVKGNTPESNRDE 2749
Query: 421 CFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQ 480
F I + G + LD E W+ ++LA
Sbjct: 2750 SFVIDRQSGRLKLEKSLDHETTKWYQFSILAR---------------------------- 2781
Query: 481 RSPVGSAVGIPQDSSAQASRVQVAIQTLDENDNAPQL-AEPYDTFVCDSAAPGQLIQVIR 539
QD + V V+IQ D NDN+P + PY+ F+ ++ G + IR
Sbjct: 2782 ---------CTQDDHEMVASVDVSIQVKDANDNSPVFESSPYEAFIVENLPGGSRVIQIR 2832
Query: 540 ALDRDEVGN 548
A D D N
Sbjct: 2833 ASDADSGTN 2841
Score = 111 bits (278), Expect = 2e-24
Identities = 119/460 (25%), Positives = 194/460 (42%), Gaps = 71/460 (15%)
Query: 92 FVIDEATGNIHVTKS-LDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKV--QDINDNPP 148
F I +G + T + DRE++ + ++ + + ++P + ++KV +D NDN P
Sbjct: 2023 FKISRTSGVLSTTGTPFDREQQEAFDVVVEVTEE--HKP-SAVAHVVVKVIVEDQNDNAP 2079
Query: 149 IFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLPFFSVDPQTGVV 208
+F PY+A V + VG + VTA D D G + ++ Y + + F + P +
Sbjct: 2080 VFVNLPYYAVVKVDTEVGHVIRYVTAVDRDS---GRNGEVHYYLKEHHEHFQIGPLGEIS 2136
Query: 209 RTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSV 268
+D +E+LV + AKD G + S V V ++ +N P F + Y +
Sbjct: 2137 LKKQFELD-TLNKEYLVTVVAKDGGNP----AFSAEVIVPITVMNKAMPVFEKPFYSAEI 2191
Query: 269 VETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDF 328
E+ + V ++A P + + YSI DG+ F+I+ + G++ V PLDF
Sbjct: 2192 AESIQVHSPVVHVQANSP---EGLKVFYSITDGDPFSQFTINFN----TGVINVIAPLDF 2244
Query: 329 ESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPE-PPAFTQAAYHLTVPENK 387
E+ +Y + AT++L G +V V + V D + PP F Q +Y +T+ E
Sbjct: 2245 EAHPAYKLSIRATDSL-------TGAHAEV-FVDIIVDDINDNPPVFAQQSYAVTLSEAS 2296
Query: 388 APGTLVGQISAADLDS-PASPIRYSIL-PHSDPERCFSIQPEEGTIHTAAPLDREARAWH 445
GT V Q+ A D DS P I Y + HS F + G I LD E H
Sbjct: 2297 VIGTSVVQVRATDSDSEPNRGISYQMFGNHSKSHDHFHVDSSTGLISLLRTLDYEQSRQH 2356
Query: 446 NLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAI 505
+ V A + G +P L +S V V +
Sbjct: 2357 TIFVRAVD---------GGMPTL-----------------------------SSDVIVTV 2378
Query: 506 QTLDENDNAPQLAEP-YDTFVCDSAAPGQLIQVIRALDRD 544
D NDN P + Y+ + + A G + ++A D D
Sbjct: 2379 DVTDLNDNPPLFEQQIYEARISEHAPHGHFVTCVKAYDAD 2418
Score = 103 bits (258), Expect = 5e-22
Identities = 121/475 (25%), Positives = 194/475 (40%), Gaps = 85/475 (17%)
Query: 94 IDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLG 153
I++ +G I +SL E + +AVD S P E ++ V + PP L
Sbjct: 2648 INKLSGVITTKESLIGLENEFFTFFVRAVDNGS-----PSKESVVLVY-VKILPPEMQLP 2701
Query: 154 P-----YHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLP-------FFSV 201
Y TV E +GT + + A +S ++Y+++ G F +
Sbjct: 2702 KFSEPFYTFTVSEDVPIGTEIDLIRAE--------HSGTVLYSLVKGNTPESNRDESFVI 2753
Query: 202 DPQTGVVRTAIPNMDRETQEEFLVVIQAK-DMGGHMGGLSGSTTVTVTLSDVNDNPPKFP 260
D Q+G ++ ++D ET + + I A+ H + S V++ + D NDN P F
Sbjct: 2754 DRQSGRLKLE-KSLDHETTKWYQFSILARCTQDDHE--MVASVDVSIQVKDANDNSPVFE 2810
Query: 261 QSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLL 320
S Y+ +VE G+ V ++RA D D G N + YS+ + E S + G +
Sbjct: 2811 SSPYEAFIVENLPGGSRVIQIRASDADSGTNGQVMYSLDQSQSVEVIE-SFAINMETGWI 2869
Query: 321 TVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPE-PPAFTQAAY 379
T K LD E + +Y +V A++ + + A V V V D + PP FT Y
Sbjct: 2870 TTLKELDHEKRDNYQIKVVASD------HGEKIQLSSTAIVDVTVTDVNDSPPRFTAEIY 2923
Query: 380 HLTVPENKAPGTLVGQISAADLDSPA--SPIRYSILPHSDPERCFSIQ--PEEGTIHTAA 435
TV E+ G ++ +S D DS + Y + DP F+++ E ++
Sbjct: 2924 KGTVSEDDPQGGVIAILSTTDADSEEINRQVTY-FITGGDPLGQFAVETIQNEWKVYVKK 2982
Query: 436 PLDREARAWHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSS 495
PLDRE R + LT+ AT+ +S
Sbjct: 2983 PLDREKRDNYLLTITATDGTFS-------------------------------------- 3004
Query: 496 AQASRVQVAIQTLDENDNAPQLAEP-YDTFVCDSAAPGQLIQVIRALDRDEVGNS 549
S+ V ++ LD NDN+P + Y + + PG+LI I A D D N+
Sbjct: 3005 ---SKAIVEVKVLDANDNSPVCEKTLYSDTIPEDVLPGKLIMQISATDADIRSNA 3056
Score = 98.6 bits (244), Expect = 2e-20
Identities = 145/595 (24%), Positives = 225/595 (37%), Gaps = 108/595 (18%)
Query: 70 SDVDRGEGRTKYLLTGEGA--GTVFVIDEATGNIHVTKSLDREEKAQ-YVLLAQAVDRAS 126
S VD EG Y+ F ID TG + +++LD E + Y L +A D
Sbjct: 486 SAVDPDEGENGYVTYSIANLNHVPFAIDHFTGAVSTSENLDYELMPRVYTLRIRASDWGL 545
Query: 127 NRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSA 186
E I + ++NDN P+F T+P VG + V+A DAD+
Sbjct: 546 PYRREVEVLATITLNNLNDNTPLFEKINCEGTIPRDLGVGEQITTVSAIDADELQL---- 601
Query: 187 KLVYTVLDG--LPFFSVDPQTGVVRTAIPNMD--------------RETQEEF------- 223
+ Y + G L FFS++P +GV+ MD E F
Sbjct: 602 -VQYQIEAGNELDFFSLNPNSGVLSLKRSLMDGLGAKVSFHSLRITATDGENFATPLYIN 660
Query: 224 --------LVVIQAKDMG------------GHMGGLSGSTTVTVTLSDVNDNPPKFPQSL 263
LV +Q ++ G + + VN + P+F +L
Sbjct: 661 ITVAASHKLVNLQCEETGVAKMLAEKLLQANKLHNQGEVEDIFFDSHSVNAHIPQFRSTL 720
Query: 264 YQ-FSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTV 322
V E G+ V + + D D G N + Y++ G F I + G+L +
Sbjct: 721 PTGIQVKENQPVGSSVIFMNSTDLDTGFNGKLVYAVSGGNEDSCFMIDME----TGMLKI 776
Query: 323 RKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLT 382
PLD E+ Y+ + T+ D ++ ++ + V V D PP F Q +Y +
Sbjct: 777 LSPLDRETTDKYTLNI----TVYDLGIPQKAAWRLLHVVVVDAND--NPPEFLQESYFVE 830
Query: 383 VPENKAPGTLVGQISAADLD-SPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREA 441
V E+K + + Q+ A D D P + YSI+ +D FSI G ++ A PLDRE
Sbjct: 831 VSEDKEVHSEIIQVEATDKDLGPNGHVTYSIVTDTD---TFSIDSVTGVVNIARPLDREL 887
Query: 442 RAWHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRV 501
+ H+L + A + ++ S V
Sbjct: 888 QHEHSLKIEARDQA------------------------------------REEPQLFSTV 911
Query: 502 QVAIQTLDENDNAPQLAEP-YDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQGPLGP 560
V + D NDN P P Y V + G +I + A D D +G S V +
Sbjct: 912 VVKVSLEDVNDNPPTFIPPNYRVKVREDLPEGTVIMWLEAHDPD-LGQSGQVRYSLLDHG 970
Query: 561 DANFTVQDNRDGSASLLLPSRPAPPRHAPYLVPIELWDWGQP-ALSSTATVTVSV 614
+ NF V D G+ ++ + + Y + + D G+P +LSST V V V
Sbjct: 971 EGNFDV-DKLSGAVRIV--QQLDFEKKQVYNLTVRAKDKGKPVSLSSTCYVEVEV 1022
Score = 76.6 bits (187), Expect = 8e-14
Identities = 129/540 (23%), Positives = 202/540 (37%), Gaps = 81/540 (15%)
Query: 81 YLLTGEGAGTVFVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKV 140
Y +T G F +D TG + V + + + + RAS+ + I V
Sbjct: 1916 YSITEGNIGEKFSMDYKTGALTVQNTTQLRSRYELTV------RASDGRFAGLTSVKINV 1969
Query: 141 QDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGN--SAKLVYTVLDGLPF 198
++ ++ F Y A V E S ++ +TA GN + L Y +L+
Sbjct: 1970 KESKESHLKFTQDVYSAVVKENSTEAETLAVITA-------IGNPINEPLFYHILNPDRR 2022
Query: 199 FSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPK 258
F + +GV+ T DRE QE F VV++ + H V V + D NDN P
Sbjct: 2023 FKISRTSGVLSTTGTPFDREQQEAFDVVVEVTEE--HKPSAVAHVVVKVIVEDQNDNAPV 2080
Query: 259 FPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDG 318
F Y V G ++ + A D D G N + Y + E E F I G G
Sbjct: 2081 FVNLPYYAVVKVDTEVGHVIRYVTAVDRDSGRNGEVHYYLK--EHHEHFQI-----GPLG 2133
Query: 319 LLTVRKPLDFES-QRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQA 377
++++K + ++ + Y V A + +PA F V + V + P F +
Sbjct: 2134 EISLKKQFELDTLNKEYLVTVVAKDGG-NPA------FSAEVIVPITVMNKAMP-VFEKP 2185
Query: 378 AYHLTVPENKAPGTLVGQISAADLDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPL 437
Y + E+ + V + A +SP + + DP F+I G I+ APL
Sbjct: 2186 FYSAEIAESIQVHSPVVHVQA---NSPEGLKVFYSITDGDPFSQFTINFNTGVINVIAPL 2242
Query: 438 DREARAWHNLTVLATELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQ 497
D EA + L++ AT+ +
Sbjct: 2243 DFEAHPAYKLSIRATD---------------------------------------SLTGA 2263
Query: 498 ASRVQVAIQTLDENDNAPQLAEP-YDTFVCDSAAPGQLIQVIRALDRDEVGNSSHVSFQ- 555
+ V V I D NDN P A+ Y + +++ G + +RA D D N +S+Q
Sbjct: 2264 HAEVFVDIIVDDINDNPPVFAQQSYAVTLSEASVIGTSVVQVRATDSDSEPNRG-ISYQM 2322
Query: 556 -GPLGPDANFTVQDNRDGSASLLLPSRPAPPRHAPYLVPIELWDWGQPALSSTATVTVSV 614
G + D+ G SLL R + + + D G P LSS VTV V
Sbjct: 2323 FGNHSKSHDHFHVDSSTGLISLLRTLDYEQSRQ--HTIFVRAVDGGMPTLSSDVIVTVDV 2380
Score = 76.3 bits (186), Expect = 1e-13
Identities = 95/421 (22%), Positives = 179/421 (42%), Gaps = 41/421 (9%)
Query: 104 TKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMS 163
T L+RE K Y L+ +A+++ +N +E ++ ++V D ND P+F Y ++PE +
Sbjct: 105 TAILNREVKDHYTLIVKALEKNTN--VEARTKVRVQVLDTNDLRPLFSPTSYSVSLPENT 162
Query: 164 NVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNMDRETQEEF 223
+ TS+ +V+A DAD G + + Y+ D F++ P +GV+ +D + +
Sbjct: 163 AIRTSIARVSATDAD---IGTNGEFYYSFKDRTDMFAIHPTSGVI-VLTGRLDYLETKLY 218
Query: 224 LVVIQAKDMGGHMGGLSGSTT---VTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGR 280
+ I A D G + G SG ++ +TV + N+ P S ++ +V
Sbjct: 219 EMEILAADRGMKLYGSSGISSMAKLTVHIEQANECAPVITAVTLSPSELDRDPAYAIV-- 276
Query: 281 LRAQDPDLGDNA-LMAYSILDGEGSEAFSISTDLQG-RDGLLTVRKPLDFESQR-SYSFR 337
D D G N + + SI+ G+ + F G ++ + +D++S Y+
Sbjct: 277 -TVDDCDQGANGDIASLSIVAGDLLQQFRTVRSFPGSKEYKVKAIGGIDWDSHPFGYNLT 335
Query: 338 VEATNTLIDPAYLRRGPFKDVASVRVAVQDAPE----PPAFTQAAYHLTVPENKAPGTLV 393
++A + P + +SV+V +P+ P F + Y + E P T V
Sbjct: 336 LQAKDKGTPPQF---------SSVKVIHVTSPQFKAGPVKFEKDVYRAEISEFAPPNTPV 386
Query: 394 GQISAADLDSPA-SPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLAT 452
+ A PA S +RY + + + FS+ G I P+ R+ A L V +
Sbjct: 387 VMVKAI----PAYSHLRY-VFKSTPGKAKFSLNYNTGLISILEPVKRQQAAHFELEVTTS 441
Query: 453 ELGWSWGPERGWVPLLVAEWSAPAAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTLDEND 512
+ + +LV A + PP+ + ++ + + ++ DE +
Sbjct: 442 D-------RKASTKVLVKVLGANSNPPEFTQTAYKAAFDENVPIGTTVMSLSAVDPDEGE 494
Query: 513 N 513
N
Sbjct: 495 N 495
Score = 75.5 bits (184), Expect = 2e-13
Identities = 89/353 (25%), Positives = 146/353 (41%), Gaps = 49/353 (13%)
Query: 115 YVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGP-------YHATVPEMSNVGT 167
Y L QA D+ + PP +KV I+ P F GP Y A + E + T
Sbjct: 332 YNLTLQAKDKGT-----PPQFSSVKV--IHVTSPQFKAGPVKFEKDVYRAEISEFAPPNT 384
Query: 168 SVIQVTAHDADDPSYGNSAKLVYTVLDGLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVI 227
V+ V A P+Y + + V+ G FS++ TG++ P + R+ F + +
Sbjct: 385 PVVMVKAI----PAYSH-LRYVFKSTPGKAKFSLNYNTGLISILEP-VKRQQAAHFELEV 438
Query: 228 QAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPD 287
D ST V V + N NPP+F Q+ Y+ + E GT V L A DPD
Sbjct: 439 TTSDR-------KASTKVLVKVLGANSNPPEFTQTAYKAAFDENVPIGTTVMSLSAVDPD 491
Query: 288 LGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFE-SQRSYSFRVEATNTLID 346
G+N + YSI + + + G ++ + LD+E R Y+ R+ A++ +
Sbjct: 492 EGENGYVTYSI-----ANLNHVPFAIDHFTGAVSTSENLDYELMPRVYTLRIRASDWGL- 545
Query: 347 PAYLRRGPFKDVASVRVAV---QDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAADLDS 403
P++ V + P F + T+P + G + +SA D D
Sbjct: 546 -------PYRREVEVLATITLNNLNDNTPLFEKINCEGTIPRDLGVGEQITTVSAIDADE 598
Query: 404 PASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARA---WHNLTVLATE 453
++Y I ++ + FS+ P G + L A +H+L + AT+
Sbjct: 599 -LQLVQYQIEAGNELD-FFSLNPNSGVLSLKRSLMDGLGAKVSFHSLRITATD 649
Score = 47.0 bits (110), Expect = 7e-05
Identities = 55/216 (25%), Positives = 90/216 (41%), Gaps = 28/216 (12%)
Query: 141 QDINDNPPIFPLGPYHATVPEMSNVGTSV-------IQVTAHDADDPSY----GNSAKLV 189
Q + P F Y+ TV E S T V + +T H A + Y G+S L
Sbjct: 25 QRLEQTPLQFTHLEYNVTVQENSAAKTYVGHPVKMGVYIT-HPAWEVRYKIVSGDSENLF 83
Query: 190 YT---VLDGLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVT 246
+L F + + G TAI N RE ++ + ++++A + ++ T V
Sbjct: 84 KAEEYILGDFCFLRIRTKGG--NTAILN--REVKDHYTLIVKALEKNTNV---EARTKVR 136
Query: 247 VTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGSEA 306
V + D ND P F + Y S+ E T + R+ A D D+G N YS D ++
Sbjct: 137 VQVLDTNDLRPLFSPTSYSVSLPENTAIRTSIARVSATDADIGTNGEFYYSFKD--RTDM 194
Query: 307 FSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATN 342
F+I G++ + LD+ + Y + A +
Sbjct: 195 FAI----HPTSGVIVLTGRLDYLETKLYEMEILAAD 226
Score = 32.7 bits (73), Expect = 1.4
Identities = 40/158 (25%), Positives = 61/158 (38%), Gaps = 22/158 (13%)
Query: 371 PPAFTQAAYHLTVPENKAPGTLVGQ--ISAADLDSPASPIRYSILPHSDPERCFS----- 423
P FT Y++TV EN A T VG + PA +RY I+ D E F
Sbjct: 31 PLQFTHLEYNVTVQENSAAKTYVGHPVKMGVYITHPAWEVRYKIV-SGDSENLFKAEEYI 89
Query: 424 --------IQPEEGTIHTAAPLDREARAWHNLTVLATELGWSWGPERGWVPLLVAEWSAP 475
I+ + G A L+RE + + L V A E + + V
Sbjct: 90 LGDFCFLRIRTKGG---NTAILNREVKDHYTLIVKALEKNTN---VEARTKVRVQVLDTN 143
Query: 476 AAPPQRSPVGSAVGIPQDSSAQASRVQVAIQTLDENDN 513
P SP +V +P++++ + S +V+ D N
Sbjct: 144 DLRPLFSPTSYSVSLPENTAIRTSIARVSATDADIGTN 181
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,487,007
Number of Sequences: 37866
Number of extensions: 2032343
Number of successful extensions: 14577
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 209
Number of HSP's successfully gapped in prelim test: 143
Number of HSP's that attempted gapping in prelim test: 8914
Number of HSP's gapped (non-prelim): 1826
length of query: 819
length of database: 18,247,518
effective HSP length: 111
effective length of query: 708
effective length of database: 14,044,392
effective search space: 9943429536
effective search space used: 9943429536
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.