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Search of human proteins with 32699028
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32699028 V-set and immunoglobulin domain containing 1 [Homo
sapiens]
(387 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32699028 V-set and immunoglobulin domain containing 1 [Homo s... 780 0.0
gi|21361429 V-set and immunoglobulin domain containing 2 [Homo s... 154 1e-37
gi|62865876 immunoglobulin superfamily, member 11 isoform b [Hom... 135 8e-32
gi|62865874 immunoglobulin superfamily, member 11 isoform a [Hom... 131 9e-31
gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens] 124 2e-28
gi|13376115 adipocyte-specific adhesion molecule [Homo sapiens] 106 3e-23
gi|4503173 coxsackie virus and adenovirus receptor precursor [Ho... 104 1e-22
gi|148664205 endothelial cell adhesion molecule [Homo sapiens] 102 6e-22
gi|10864029 junctional adhesion molecule 2 precursor [Homo sapiens] 71 1e-12
gi|61966777 V-set and immunoglobulin domain containing 8 [Homo s... 69 9e-12
gi|8393638 F11 receptor precursor [Homo sapiens] 68 2e-11
gi|21361905 junctional adhesion molecule 3 precursor [Homo sapiens] 67 4e-11
gi|121674801 hepatocyte cell adhesion molecule [Homo sapiens] 67 4e-11
gi|4505243 myelin protein zero [Homo sapiens] 64 2e-10
gi|46358426 myelin protein zero-like 1 isoform b [Homo sapiens] 63 4e-10
gi|4506357 myelin protein zero-like 1 isoform a [Homo sapiens] 63 4e-10
gi|139948432 adlican [Homo sapiens] 62 9e-10
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 59 6e-09
gi|38093645 myelin protein zero-like 3 [Homo sapiens] 57 2e-08
gi|62000702 diacylglycerol kinase kappa [Homo sapiens] 55 8e-08
gi|11386199 poliovirus receptor-related 3 [Homo sapiens] 54 2e-07
gi|38490688 immunoglobulin superfamily, member 10 [Homo sapiens] 54 2e-07
gi|13376852 CD276 antigen isoform b [Homo sapiens] 54 2e-07
gi|110349719 titin isoform N2-A [Homo sapiens] 54 3e-07
gi|67188443 CD276 antigen isoform a [Homo sapiens] 54 3e-07
gi|28373126 contactin 4 isoform c precursor [Homo sapiens] 54 3e-07
gi|28373122 contactin 4 isoform a precursor [Homo sapiens] 54 3e-07
gi|54607118 leucine-rich repeats and immunoglobulin-like domains... 54 3e-07
gi|118572606 hemicentin 1 [Homo sapiens] 53 4e-07
gi|4759066 sodium channel, voltage-gated, type II, beta [Homo sa... 53 5e-07
>gi|32699028 V-set and immunoglobulin domain containing 1 [Homo
sapiens]
Length = 387
Score = 780 bits (2013), Expect = 0.0
Identities = 387/387 (100%), Positives = 387/387 (100%)
Query: 1 MVFAFWKVFLILSCLAGQVSVVQVTIPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWS 60
MVFAFWKVFLILSCLAGQVSVVQVTIPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWS
Sbjct: 1 MVFAFWKVFLILSCLAGQVSVVQVTIPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWS 60
Query: 61 FFHKKEMEPISIYFSQGGQAVAIGQFKDRITGSNDPGNASITISHMQPADSGIYICDVNN 120
FFHKKEMEPISIYFSQGGQAVAIGQFKDRITGSNDPGNASITISHMQPADSGIYICDVNN
Sbjct: 61 FFHKKEMEPISIYFSQGGQAVAIGQFKDRITGSNDPGNASITISHMQPADSGIYICDVNN 120
Query: 121 PPDFLGQNQGILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLEGR 180
PPDFLGQNQGILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLEGR
Sbjct: 121 PPDFLGQNQGILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLEGR 180
Query: 181 DIVPVKENFNPTTGILVIGNLTNFEQGYYQCTAINRLGNSSCEIDLTSSHPEVGIIVGAL 240
DIVPVKENFNPTTGILVIGNLTNFEQGYYQCTAINRLGNSSCEIDLTSSHPEVGIIVGAL
Sbjct: 181 DIVPVKENFNPTTGILVIGNLTNFEQGYYQCTAINRLGNSSCEIDLTSSHPEVGIIVGAL 240
Query: 241 IGSLVGAAIIISVVCFARNKAKAKAKERNSKTIAELEPMTKINPRGESEAMPREDATQLE 300
IGSLVGAAIIISVVCFARNKAKAKAKERNSKTIAELEPMTKINPRGESEAMPREDATQLE
Sbjct: 241 IGSLVGAAIIISVVCFARNKAKAKAKERNSKTIAELEPMTKINPRGESEAMPREDATQLE 300
Query: 301 VTLPSSIHETGPDTIQEPDYEPKPTQEPAPEPAPGSEPMAVPDLDIELELEPETQSELEP 360
VTLPSSIHETGPDTIQEPDYEPKPTQEPAPEPAPGSEPMAVPDLDIELELEPETQSELEP
Sbjct: 301 VTLPSSIHETGPDTIQEPDYEPKPTQEPAPEPAPGSEPMAVPDLDIELELEPETQSELEP 360
Query: 361 EPEPEPESEPGVVVEPLSEDEKGVVKA 387
EPEPEPESEPGVVVEPLSEDEKGVVKA
Sbjct: 361 EPEPEPESEPGVVVEPLSEDEKGVVKA 387
>gi|21361429 V-set and immunoglobulin domain containing 2 [Homo
sapiens]
Length = 327
Score = 154 bits (389), Expect = 1e-37
Identities = 100/308 (32%), Positives = 163/308 (52%), Gaps = 21/308 (6%)
Query: 9 FLILSCLAGQVSVVQVTIPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWSFFHK---- 64
FL LS LA V+V +P ++ +G L C Y+T+V + +++WSF
Sbjct: 16 FLCLSGLA-----VEVKVPTEPLSTPLGKTAELTCTYSTSVG--DSFALEWSFVQPGKPI 68
Query: 65 KEMEPISIYFSQGGQAVAIGQFKDRITGSNDP---GNASITISHMQPADSGIYICDVNNP 121
E PI +YF+ G G R++ +P G A++ ++ + P+D+G Y+C VNNP
Sbjct: 69 SESHPI-LYFTNG-HLYPTGSKSKRVSLLQNPPTVGVATLKLTDVHPSDTGTYLCQVNNP 126
Query: 122 PDFLGQNQGILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLEGRD 181
PDF G++N++VLV PS PLCS G+ G + +L C S+ G P PVY W +L G
Sbjct: 127 PDFYTNGLGLINLTVLVPPSNPLCSQSGQTSVGGSTALRCSSSEGAPKPVYNWVRL-GTF 185
Query: 182 IVPVKENF--NPTTGILVIGNLTNFEQGYYQCTAINRLGNSSCEIDLTSSHPEVGIIVGA 239
P + + +G L++ NL+ G Y+C A N++G++SCE+ L+ + P G + GA
Sbjct: 186 PTPSPGSMVQDEVSGQLILTNLSLTSSGTYRCVATNQMGSASCELTLSVTEPSQGRVAGA 245
Query: 240 LIGSLVGAAII-ISVVCFARNKAKAKAKERNSKTIAELEPMTKINPRGESEAMPREDATQ 298
LIG L+G ++ ++ C R + + K + + ++L I P R D+++
Sbjct: 246 LIGVLLGVLLLSVAAFCLVRFQKERGKKPKETYGGSDLRE-DAIAPGISEHTCMRADSSK 304
Query: 299 LEVTLPSS 306
+ PSS
Sbjct: 305 GFLERPSS 312
>gi|62865876 immunoglobulin superfamily, member 11 isoform b [Homo
sapiens]
Length = 431
Score = 135 bits (339), Expect = 8e-32
Identities = 91/282 (32%), Positives = 136/282 (48%), Gaps = 22/282 (7%)
Query: 10 LILSCLAGQVSVVQVTIPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWSFFHKKEM-E 68
L+L L G + ++V+ G + V G L C +TT+ A+ L++ W +
Sbjct: 11 LLLLSLHGVAASLEVSESPGSIQVARGQPAVLPCTFTTS-AALINLNVIWMVTPLSNANQ 69
Query: 69 PISIYFSQGGQAV-AIGQFKDRI--TGSNDPGNASITISHMQPADSGIYICDVNNPPDFL 125
P + QGGQ +F R+ TG+ N SI I++ Q +D+G Y C VNN PD
Sbjct: 70 PEQVILYQGGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIG 129
Query: 126 GQNQGILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLEGRDIVPV 185
G+N G+ ++VLV PS P C +QG + G + L C S G P P Y W KL+ +P
Sbjct: 130 GRNIGVTGLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPP 189
Query: 186 KENFNPTTGILVIGNLTNFEQGYYQCTAINRLGNSSCEIDLTSSHPE---VGIIVGALIG 242
+ G + I N++ G YQC A N +G S+C +DL P+ +G+I GA
Sbjct: 190 TATQDQVQGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRNIGLIAGA--- 246
Query: 243 SLVGAAIIISVVCFA---------RNKAKAKAKERNSKTIAE 275
+G +I + C A R+K K + +E I E
Sbjct: 247 --IGTGAVIIIFCIALILGAFFYWRSKNKEEEEEEIPNEIRE 286
>gi|62865874 immunoglobulin superfamily, member 11 isoform a [Homo
sapiens]
Length = 430
Score = 131 bits (330), Expect = 9e-31
Identities = 88/275 (32%), Positives = 132/275 (48%), Gaps = 22/275 (8%)
Query: 17 GQVSVVQVTIPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWSFFHKKEM-EPISIYFS 75
G + ++V+ G + V G L C +TT+ A+ L++ W +P +
Sbjct: 17 GVAASLEVSESPGSIQVARGQPAVLPCTFTTS-AALINLNVIWMVTPLSNANQPEQVILY 75
Query: 76 QGGQAV-AIGQFKDRI--TGSNDPGNASITISHMQPADSGIYICDVNNPPDFLGQNQGIL 132
QGGQ +F R+ TG+ N SI I++ Q +D+G Y C VNN PD G+N G+
Sbjct: 76 QGGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPDIGGRNIGVT 135
Query: 133 NVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPT 192
++VLV PS P C +QG + G + L C S G P P Y W KL+ +P +
Sbjct: 136 GLTVLVPPSAPHCQIQGSQDIGSDVILLCSSEEGIPRPTYLWEKLDNTLKLPPTATQDQV 195
Query: 193 TGILVIGNLTNFEQGYYQCTAINRLGNSSCEIDLTSSHPE---VGIIVGALIGSLVGAAI 249
G + I N++ G YQC A N +G S+C +DL P+ +G+I GA +G
Sbjct: 196 QGTVTIRNISALSSGLYQCVASNAIGTSTCLLDLQVISPQPRNIGLIAGA-----IGTGA 250
Query: 250 IISVVCFA---------RNKAKAKAKERNSKTIAE 275
+I + C A R+K K + +E I E
Sbjct: 251 VIIIFCIALILGAFFYWRSKNKEEEEEEIPNEIRE 285
>gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens]
Length = 319
Score = 124 bits (310), Expect = 2e-28
Identities = 97/340 (28%), Positives = 156/340 (45%), Gaps = 34/340 (10%)
Query: 1 MVFAFWKVFLILSCLAGQVSVVQVTIPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWS 60
MV W V L + V + V P + + G +VTL C Y T+ +SRE L IQW
Sbjct: 1 MVGKMWPVLWTLCAVRVTVDAISVETPQDVLRASQGKSVTLPCTYHTSTSSREGL-IQWD 59
Query: 61 FFHKKEMEPISIYFSQGGQAVAIGQFKDRITGSN--DPGNASITISHMQPADSGIYICDV 118
E + I+ + +K+R++ SN + +ASITI + AD+G Y C V
Sbjct: 60 KLLLTHTERVVIWPFSNKNYIHGELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSV 119
Query: 119 NNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLE 178
+ D G + + + VLV PSKP C ++G G+ I L+C S G+P+P Y W +
Sbjct: 120 SLMSDLEGNTKSRVRLLVLVPPSKPECGIEGETIIGNNIQLTCQSKEGSPTPQYSWKRY- 178
Query: 179 GRDIVPVKENF-NPTTGILV-IGNLTNFEQGYYQCTAINRLGNSSCEIDLTSSHP--EVG 234
+I+ ++ P +G V + N++ GYY CT+ N G C I + P V
Sbjct: 179 --NILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGTQFCNITVAVRSPSMNVA 236
Query: 235 IIVGALIGSLVGAAIIISVVCFARNKAKAKAKERNSKTIAELEPMTKINPRGESEAMPRE 294
+ VG +G +V A III ++ + + K+ N++ + +A P
Sbjct: 237 LYVGIAVG-VVAALIIIGIIIYC---CCCRGKDDNTE--------------DKEDARPNR 278
Query: 295 DATQLEVTLPSSIHETGPDTIQEPDY---EPKPTQEPAPE 331
+A + P + E + +E DY E + T +P+
Sbjct: 279 EAYE---EPPEQLRELSREREEEDDYRQEEQRSTGRESPD 315
>gi|13376115 adipocyte-specific adhesion molecule [Homo sapiens]
Length = 373
Score = 106 bits (265), Expect = 3e-23
Identities = 90/322 (27%), Positives = 154/322 (47%), Gaps = 23/322 (7%)
Query: 39 VTLICIYTTTVASREQLSIQWSFFHKKEMEPISI-YFSQGGQAVAIGQFKDRITGSND-- 95
VTL C + + ++ L I+W + + + I Y S+ + K R+ +++
Sbjct: 31 VTLPCHHQLGLPEKDTLDIEWLLTDNEGNQKVVITYSSRHVYNNLTEEQKGRVAFASNFL 90
Query: 96 PGNASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPETGH 155
G+AS+ I ++P+D G Y C V N ++ + + + VLV+PSKP C ++G G
Sbjct: 91 AGDASLQIEPLKPSDEGRYTCKVKNSGRYVWSH---VILKVLVRPSKPKCELEGELTEGS 147
Query: 156 TISLSCLSALGTPSPVYYWHKL---EGRD-IVPVKENFNPT-TGILVIGNLTNFEQGYYQ 210
++L C S+ GT VYYW ++ EG D +P K + G +++ NLT G YQ
Sbjct: 148 DLTLQCESSSGTEPIVYYWQRIREKEGEDERLPPKSRIDYNHPGRVLLQNLTMSYSGLYQ 207
Query: 211 CTAINRLGNSSCEIDLTSSHPE-VGIIVGALIGSLVGAAIIISVVCF---ARNKAKAKAK 266
CTA N G SC + +T + + +G++ GA+ G + GA +I +V ++K + + +
Sbjct: 208 CTAGNEAGKESCVVRVTVQYVQSIGMVAGAVTGIVAGALLIFLLVWLLIRRKDKERYEEE 267
Query: 267 ERNSKTIAELE-PMTKINPRGESEAMPREDATQLEVTLPSSIHETGPDTIQEPDYEPKP- 324
ER ++ + E P ++ S + R + T ++ + D P+P
Sbjct: 268 ERPNEIREDAEAPKARLVKPSSSSSGSRSSRSGSSSTRSTANSASRSQRTLSTDAAPQPG 327
Query: 325 --TQE---PAPEPAPGSEPMAV 341
TQ PE GSEP V
Sbjct: 328 LATQAYSLVGPE-VRGSEPKKV 348
>gi|4503173 coxsackie virus and adenovirus receptor precursor [Homo
sapiens]
Length = 365
Score = 104 bits (260), Expect = 1e-22
Identities = 88/355 (24%), Positives = 153/355 (43%), Gaps = 26/355 (7%)
Query: 9 FLILSCLAGQVSVVQVTIPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWSFFHKKEME 68
F++L + + +T P+ + G L C +T + + L I+W +
Sbjct: 7 FVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQK 66
Query: 69 PISIYFSQGGQAVAIGQFKDRITG-----SND--PGNASITISHMQPADSGIYICDVNNP 121
+ G + + D + G SND G+ASI ++++Q +D G Y C V
Sbjct: 67 VDQVIILYSGDKIYDDYYPD-LKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKA 125
Query: 122 PDFLGQNQGILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLEGRD 181
P + +++ VLVKPS C V G E G + C G+ Y W KL
Sbjct: 126 PGVANKK---IHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSDSQ 182
Query: 182 IVPVKENFNPTTGILVIGNLTNFEQGYYQCTAINRLGNSSCEIDLTSSHP--EVGIIVGA 239
+P T+ ++ + N ++ G Y CT NR+G+ C + L P + G+I GA
Sbjct: 183 KMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGLIAGA 242
Query: 240 LIGSLVGAAII-ISVVCFARNKAKAKAKERNSKTIAELEPMTKINPRGESEAMPREDATQ 298
+IG+L+ A+I + + C + + + K ++ I E P K + + + + +
Sbjct: 243 IIGTLLALALIGLIIFCCRKKRREEKYEKEVHHDIREDVPPPK-SRTSTARSYIGSNHSS 301
Query: 299 LEVTLPSSIH---ETGPDTIQEPDYE---PKPTQEPAPEPAP-----GSEPMAVP 342
L PS++ +T + + D+E PT PA AP G+ P+ +P
Sbjct: 302 LGSMSPSNMEGYSKTQYNQVPSEDFERTPQSPTLPPAKVAAPNLSRMGAIPVMIP 356
>gi|148664205 endothelial cell adhesion molecule [Homo sapiens]
Length = 390
Score = 102 bits (254), Expect = 6e-22
Identities = 97/349 (27%), Positives = 149/349 (42%), Gaps = 35/349 (10%)
Query: 8 VFLILSCLAGQVSV-VQVTIPDGFVNVTVGSNVTLICIYTT--TVASREQLSIQWS--FF 62
+FL LS LA +Q+ +P + G V L YT V+S + + + FF
Sbjct: 16 LFLGLSALAPPSRAQLQLHLPANRLQAVEGGEVVLPAWYTLHGEVSSSQPWEVPFVMWFF 75
Query: 63 HKKEMEPISIYFSQGGQAVAIGQFKDRITGSNDPGNASITISHMQPADSGIYICDVNNPP 122
+KE E + + G V + + S N S+ + +Q DSG Y C VN
Sbjct: 76 KQKEKEDQVLSYING---VTTSKPGVSLVYSMPSRNLSLRLEGLQEKDSGPYSCSVN-VQ 131
Query: 123 DFLGQNQG----ILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLE 178
D G+++G L ++VLV P+ P C +QG P G ++LSC S P+ Y W
Sbjct: 132 DKQGKSRGHSIKTLELNVLVPPAPPSCRLQGVPHVGANVTLSCQSPRSKPAVQYQW---- 187
Query: 179 GRDIVPVKENFNPT----TGILVIGNLTNFEQGYYQCTAINRLGNSSCEIDL-TSSHPEV 233
R + + F P G L + NL++ G Y C A N +G + C + L S+ P
Sbjct: 188 DRQLPSFQTFFAPALDVIRGSLSLTNLSSSMAGVYVCKAHNEVGTAQCNVTLEVSTGPGA 247
Query: 234 GIIVGALIGSLVGAAIIISVVCFARNKAKAKAKERNSKTIAELEPMTKINPRGESEAMPR 293
++ GA++G+LVG ++ +V + KA + N + P T P+
Sbjct: 248 AVVAGAVVGTLVGLGLLAGLVLLYHRRGKALEEPANDIKEDAIAPRTLPWPKS------- 300
Query: 294 EDATQLEVTLPSSIHETGPDTIQEPDYEPKPTQEPAPEPAPGSEPMAVP 342
D TL S T ++ P P+P A P P A+P
Sbjct: 301 SDTISKNGTLSS---VTSARALRPPHGPPRP---GALTPTPSLSSQALP 343
>gi|10864029 junctional adhesion molecule 2 precursor [Homo sapiens]
Length = 298
Score = 71.2 bits (173), Expect = 1e-12
Identities = 67/234 (28%), Positives = 106/234 (45%), Gaps = 46/234 (19%)
Query: 48 TVASREQLSIQWSFFHKKEMEPIS-IYFSQGGQAVAIGQFKDRITGSNDPGNASITISHM 106
TV+SR ++W KK +S +Y+ Q Q G FK+R + + +I I ++
Sbjct: 56 TVSSR----LEW----KKLGRSVSFVYYQQTLQ----GDFKNRA----EMIDFNIRIKNV 99
Query: 107 QPADSGIYICDVNNPPDFLGQN--QGILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSA 164
+D+G Y C+V+ P + GQN + + + VLV P+ P C V +G + L C
Sbjct: 100 TRSDAGKYRCEVSAPSE-QGQNLEEDTVTLEVLVAPAVPSCEVPSSALSGTVVELRCQDK 158
Query: 165 LGTPSPVYYWHK-----LE----GRDIVPVKENFNPTTGILVIGNLTNFEQGYYQCTAIN 215
G P+P Y W K LE G N TG L ++ + G Y C A N
Sbjct: 159 EGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKTGTLQFNTVSKLDTGEYSCEARN 218
Query: 216 RLGNSSC-----EIDLTSSHPEVGIIVGALIGSLVGAAIIISV----VCFARNK 260
+G C ++D + + +I ++V A++ISV VC+A+ K
Sbjct: 219 SVGYRRCPGKRMQVD--------DLNISGIIAAVVVVALVISVCGLGVCYAQRK 264
>gi|61966777 V-set and immunoglobulin domain containing 8 [Homo
sapiens]
Length = 414
Score = 68.6 bits (166), Expect = 9e-12
Identities = 68/275 (24%), Positives = 125/275 (45%), Gaps = 48/275 (17%)
Query: 10 LILSCLA-GQVSVVQVTIPDG--FVNVTVGSNVTLICIYTTTVASR--EQLSIQWSFF-- 62
L+L CL+ +S V++ DG + + G NV L C Y L I+W
Sbjct: 9 LLLVCLSPALLSAVRIN-GDGQEVLYLAEGDNVRLGCPYVLDPEDYGPNGLDIEWMQVNS 67
Query: 63 ---HKKEMEPISIYFSQGGQAVAIGQF---KDRIT-GSNDPG--NASITISHMQPADSGI 113
H +E +++ S + + G + R+ ++DP +ASI + ++Q +D+
Sbjct: 68 DPAHHRE----NVFLSYQDKRINHGSLPHLQQRVRFAASDPSQYDASINLMNLQVSDTAT 123
Query: 114 YICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYY 173
Y C V + + I V+V +P+ P+C +G G+ + L C ++ G+ Y
Sbjct: 124 YECRVKKTT--MATRKVI--VTVQARPAVPMCWTEGHMTYGNDVVLKCYASGGSQPLSYK 179
Query: 174 WHKLEGRDI----------------VPVKENFNPT------TGILVIGNLTNFEQGYYQC 211
W K+ G + +E+F+ + G LV+ +++ + G YQC
Sbjct: 180 WAKISGHHYPYRAGSYTSQHSYHSELSYQESFHSSINQGLNNGDLVLKDISRADDGLYQC 239
Query: 212 TAINRLGNSSCEIDL-TSSHPEVGIIVGALIGSLV 245
T N +G S C +++ S +G+I+G ++GSL+
Sbjct: 240 TVANNVGYSVCVVEVKVSDSRRIGVIIGIVLGSLL 274
>gi|8393638 F11 receptor precursor [Homo sapiens]
Length = 299
Score = 67.8 bits (164), Expect = 2e-11
Identities = 74/296 (25%), Positives = 119/296 (40%), Gaps = 50/296 (16%)
Query: 11 ILSCLAGQVSVVQVTIPDGFVNVTVGSN--VTLICIYTTTVASREQLSIQWSFFHKKEME 68
IL+ L +++ VT+ V + N V L C Y+ + R ++W F
Sbjct: 16 ILAILLCSLALGSVTVHSSEPEVRIPENNPVKLSCAYSGFSSPR----VEWKF------- 64
Query: 69 PISIYFSQGGQAVAIGQFKDRITGSNDPG----NASITISHMQPADSGIYICDVNNPPDF 124
G + + ++IT S + IT + D+G Y C V+
Sbjct: 65 -------DQGDTTRLVCYNNKITASYEDRVTFLPTGITFKSVTREDTGTYTCMVSEEG-- 115
Query: 125 LGQNQGILNVS--VLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLEGRDI 182
G + G + V VLV PSKP ++ G+ L+C G+P Y W K D
Sbjct: 116 -GNSYGEVKVKLIVLVPPSKPTVNIPSSATIGNRAVLTCSEQDGSPPSEYTWFK----DG 170
Query: 183 VPVKEN-------------FNPTTGILVIGNLTNFEQGYYQCTAINRLGN--SSCEIDLT 227
+ + N NPTTG LV L+ + G Y C A N G +S + +
Sbjct: 171 IVMPTNPKSTRAFSNSSYVLNPTTGELVFDPLSASDTGEYSCEARNGYGTPMTSNAVRME 230
Query: 228 SSHPEVGIIVGALIGSLVGAAIIISVVCFA--RNKAKAKAKERNSKTIAELEPMTK 281
+ VG+IV A++ +L+ I++ + FA R K +SK + +P +
Sbjct: 231 AVERNVGVIVAAVLVTLILLGILVFGIWFAYSRGHFDRTKKGTSSKKVIYSQPSAR 286
>gi|21361905 junctional adhesion molecule 3 precursor [Homo sapiens]
Length = 355
Score = 66.6 bits (161), Expect = 4e-11
Identities = 66/266 (24%), Positives = 112/266 (42%), Gaps = 30/266 (11%)
Query: 5 FWKVFLILSCLAGQVSVVQVTIPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWSFFHK 64
F+ + L CL G V++ + V +V L CI T + S + I+W
Sbjct: 63 FFLLLLFRGCLIGAVNLKS---SNRTPVVQEFESVELSCIITDSQTSDPR--IEWKKI-- 115
Query: 65 KEMEPISIYFSQGGQAVAIGQFKDRITGSNDPGNASITISHMQPADSGIYICDVNNPPDF 124
++ + ++F Q G+ + G S+ I ++ DS +Y C+V D
Sbjct: 116 QDEQTTYVFFDNKIQGDLAGR-------AEILGKTSLKIWNVTRRDSALYRCEVVARNDR 168
Query: 125 LGQNQGILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLEGRDI-V 183
++ ++ ++V VKP P+C V G +L C + G P P Y W++ D+ +
Sbjct: 169 KEIDEIVIELTVQVKPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYR---NDVPL 225
Query: 184 PVKENFNP-----------TTGILVIGNLTNFEQGYYQCTAINRLGNSSC-EIDLTSSHP 231
P NP TG LV + + G Y C A N G++ C E ++
Sbjct: 226 PTDSRANPRFRNSSFHLNSETGTLVFTAVHKDDSGQYYCIASNDAGSARCEEQEMEVYDL 285
Query: 232 EVGIIVGALIGSLVGAAIIISVVCFA 257
+G I+G ++ L A+I +C A
Sbjct: 286 NIGGIIGGVLVVLAVLALITLGICCA 311
>gi|121674801 hepatocyte cell adhesion molecule [Homo sapiens]
Length = 416
Score = 66.6 bits (161), Expect = 4e-11
Identities = 75/322 (23%), Positives = 137/322 (42%), Gaps = 25/322 (7%)
Query: 22 VQVTIPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWSFFHKKEMEPISIYFSQGGQAV 81
V +T P ++ TVG + L Y++T + R ++W K +P+++ S G + +
Sbjct: 34 VNITSPVRLIHGTVGKSALLSVQYSSTSSDRPV--VKWQL---KRDKPVTVVQSIGTEVI 88
Query: 82 AI--GQFKDRITGSNDPGNASITISHMQPADSGIYICDVNNPPD-FLGQNQGILNVSVLV 138
++DRI N S+ +S +Q AD G Y +++ D F G+ L V V +
Sbjct: 89 GTLRPDYRDRIRLFE---NGSLLLSDLQLADEGTYEVEISITDDTFTGEKTINLTVDVPI 145
Query: 139 KPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLEGRDIV-PVKENFNPTTGILV 197
+ L + E +L+C GT P Y W K +G+ ++ + +P +L
Sbjct: 146 SRPQVLVASTTVLELSEAFTLNCSHENGT-KPSYTWLK-DGKPLLNDSRMLLSPDQKVLT 203
Query: 198 IGNLTNFEQGYYQCTAINRLGNS-SCEIDLTSSHPEVGIIVGALIGSLVGAAIIISVVCF 256
I + + Y C N + S + +T I+ + G + ++ C+
Sbjct: 204 ITRVLMEDDDLYSCMVENPISQGRSLPVKITVYRRSSLYIILSTGGIFLLVTLVTVCACW 263
Query: 257 ARNKAKAKAKERNSKTIAELEPMTKINPRGESEAMPREDATQLEVTLPSSIHETGPDTIQ 316
+K K K E+ + LE M + + R + EA + + E P +++ I
Sbjct: 264 KPSKRKQKKLEKQNS----LEYMDQNDDRLKPEADTLPRSGEQERKNPMALY------IL 313
Query: 317 EPDYEPKPTQEPAPEPAPGSEP 338
+ P+ + PAPEP +EP
Sbjct: 314 KDKDSPETEENPAPEPRSATEP 335
>gi|4505243 myelin protein zero [Homo sapiens]
Length = 258
Score = 63.9 bits (154), Expect = 2e-10
Identities = 40/126 (31%), Positives = 63/126 (50%), Gaps = 4/126 (3%)
Query: 10 LILSCLAGQVSVVQVTIPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWSFFHKKEMEP 69
L+ S L + V D V+ VGS VTL C + ++ + +S W + + +
Sbjct: 27 LLFSSLVLSPAQAIVVYTDREVHGAVGSRVTLHCSFWSSEWVSDDISFTWRYQPEGGRDA 86
Query: 70 ISIYFSQGGQAVA--IGQFKDRITGSNDPG--NASITISHMQPADSGIYICDVNNPPDFL 125
ISI+ GQ +G FK+RI DP + SI I ++ +D+G + CDV NPPD +
Sbjct: 87 ISIFHYAKGQPYIDEVGTFKERIQWVGDPRWKDGSIVIHNLDYSDNGTFTCDVKNPPDIV 146
Query: 126 GQNQGI 131
G+ +
Sbjct: 147 GKTSQV 152
>gi|46358426 myelin protein zero-like 1 isoform b [Homo sapiens]
Length = 209
Score = 63.2 bits (152), Expect = 4e-10
Identities = 51/148 (34%), Positives = 73/148 (49%), Gaps = 9/148 (6%)
Query: 6 WKVFLI-LSCLAGQVSVVQVTIPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWSFFHK 64
W V L L VS ++V P + V G+ L C + +T + S+ WSF +
Sbjct: 21 WSVLAAALGLLTAGVSALEVYTPKE-IFVANGTQGKLTCKFKSTSTTGGLTSVSWSFQPE 79
Query: 65 KEMEPISIYFSQGGQAVAIGQ---FKDRIT--GSNDPGNASITISHMQPADSGIYICDVN 119
+S + GQ V +G FKDRI+ G D +ASI I +MQ +G YICDV
Sbjct: 80 GADTTVSFFHYSQGQ-VYLGNYPPFKDRISWAGDLDKKDASINIENMQFIHNGTYICDVK 138
Query: 120 NPPDFLGQNQGILNVSVLVKPSKPLCSV 147
NPPD + Q G + + V+ K + P+ V
Sbjct: 139 NPPDIVVQ-PGHIRLYVVEKENLPVFPV 165
>gi|4506357 myelin protein zero-like 1 isoform a [Homo sapiens]
Length = 269
Score = 63.2 bits (152), Expect = 4e-10
Identities = 51/148 (34%), Positives = 73/148 (49%), Gaps = 9/148 (6%)
Query: 6 WKVFLI-LSCLAGQVSVVQVTIPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWSFFHK 64
W V L L VS ++V P + V G+ L C + +T + S+ WSF +
Sbjct: 21 WSVLAAALGLLTAGVSALEVYTPKE-IFVANGTQGKLTCKFKSTSTTGGLTSVSWSFQPE 79
Query: 65 KEMEPISIYFSQGGQAVAIGQ---FKDRIT--GSNDPGNASITISHMQPADSGIYICDVN 119
+S + GQ V +G FKDRI+ G D +ASI I +MQ +G YICDV
Sbjct: 80 GADTTVSFFHYSQGQ-VYLGNYPPFKDRISWAGDLDKKDASINIENMQFIHNGTYICDVK 138
Query: 120 NPPDFLGQNQGILNVSVLVKPSKPLCSV 147
NPPD + Q G + + V+ K + P+ V
Sbjct: 139 NPPDIVVQ-PGHIRLYVVEKENLPVFPV 165
>gi|139948432 adlican [Homo sapiens]
Length = 2828
Score = 62.0 bits (149), Expect = 9e-10
Identities = 69/275 (25%), Positives = 112/275 (40%), Gaps = 25/275 (9%)
Query: 97 GNASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPL----CSVQGRPE 152
GN S+ I ++ +DS +C N G+ + IL ++VL KP+ S +
Sbjct: 2499 GNGSLDIRSLRKSDSVQLVCMARNEG---GEARLILQLTVLEPMEKPIFHDPISEKITAM 2555
Query: 153 TGHTISLSCLSALGTPSPVYYWHKLEGRDIVP---VKENFNPTTGILVIGNLTNFEQGYY 209
GHTISL+C SA GTP+P W G D+ ++ ++ G+L I L++ + G Y
Sbjct: 2556 AGHTISLNC-SAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKADGMLHISGLSSVDAGAY 2614
Query: 210 QCTAINRLGNSSCEIDL-TSSHPEVGIIVGALIGSLVGAAIIISVVCFARNKAKAKAKER 268
+C A N G++ + L PE L+ + G + + + +
Sbjct: 2615 RCVARNAAGHTERLVSLKVGLKPEANKQYHNLVSIINGETLKLPCTPPGAGQGRFSWTLP 2674
Query: 269 NSKTIAELEPMTKINPRGESEAMPREDATQLEVTLPSSIH-ETGPDTIQEP----DYEPK 323
N + + + +++ RE + T + E GP P Y P+
Sbjct: 2675 NGMHLEGPQTLGRVSLLDNGTLTVREASVFDRGTYVCRMETEYGPSVTSIPVIVIAYPPR 2734
Query: 324 PTQEPAP--EPAPGSE------PMAVPDLDIELEL 350
T EP P PG+ M +P DI EL
Sbjct: 2735 ITSEPTPVIYTRPGNTVKLNCMAMGIPKADITWEL 2769
Score = 47.4 bits (111), Expect = 2e-05
Identities = 46/218 (21%), Positives = 86/218 (39%), Gaps = 32/218 (14%)
Query: 98 NASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPETGHTI 157
N ++ + + D+G Y+C N +G + +L V V++KP+K ++ + E H +
Sbjct: 2203 NGTLVVKSVTDKDAGDYLCVARNK---VGDDYVVLKVDVVMKPAK----IEHKEENDHKV 2255
Query: 158 ------SLSCLSALGTPSPVYYWHKLEG---RDIVPVKENFNPTTGILVIGNLTNF---- 204
+ C+ A G P+P W +G + ++ T +V N T +
Sbjct: 2256 FYGGDLKVDCV-ATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNEV 2314
Query: 205 ---EQGYYQCTAINRLGNSSCEIDLTSSHPEVGIIVGALIGSLVGAAIIISVVCFARNKA 261
E+G Y C A N++G + + I + V +++V C A+ +
Sbjct: 2315 GMREEGDYTCFAENQVGKDEMRVRVKVVTAPATIRNKTYLAVQVPYGDVVTVACEAKGEP 2374
Query: 262 KAKAKERNSKTIAELEPMTKINPRGESEAMPREDATQL 299
K + L P K+ P + +D T L
Sbjct: 2375 MPK--------VTWLSPTNKVIPTSSEKYQIYQDGTLL 2404
Score = 43.9 bits (102), Expect = 2e-04
Identities = 37/134 (27%), Positives = 57/134 (42%), Gaps = 16/134 (11%)
Query: 98 NASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKP----SKPLCSVQGRPET 153
N ++T+ D G Y+C + G + + V V+ P S+P + RP
Sbjct: 2693 NGTLTVREASVFDRGTYVCRMETE---YGPSVTSIPVIVIAYPPRITSEPTPVIYTRP-- 2747
Query: 154 GHTISLSCLSALGTPSPVYYW------HKLEGRDIVPVKENFNPTTGILVIGNLTNFEQG 207
G+T+ L+C+ A+G P W H G F G L I + T + G
Sbjct: 2748 GNTVKLNCM-AMGIPKADITWELPDKSHLKAGVQARLYGNRFLHPQGSLTIQHATQRDAG 2806
Query: 208 YYQCTAINRLGNSS 221
+Y+C A N LG+ S
Sbjct: 2807 FYKCMAKNILGSDS 2820
Score = 41.6 bits (96), Expect = 0.001
Identities = 33/138 (23%), Positives = 58/138 (42%), Gaps = 5/138 (3%)
Query: 101 ITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPETGHTISLS 160
+ I M+P+DSG+Y C + +L S +P++ G+ G +++L
Sbjct: 540 LRIKSMEPSDSGLYQCIAQVRDEMDRMVYRVLVQSPSTQPAEKDTVTIGK-NPGESVTLP 598
Query: 161 CLSALGTPSPVYYWHKLEGR---DIVPVKENFNPTTGILVIGNLTNFEQGYYQCTAINRL 217
C +AL P W R D+ + G L I + + GYY+C A+N+
Sbjct: 599 C-NALAIPEAHLSWILPNRRIINDLANTSHVYMLPNGTLSIPKVQVSDSGYYRCVAVNQQ 657
Query: 218 GNSSCEIDLTSSHPEVGI 235
G + +T + G+
Sbjct: 658 GADHFTVGITVTKKGSGL 675
Score = 41.2 bits (95), Expect = 0.002
Identities = 40/139 (28%), Positives = 62/139 (44%), Gaps = 18/139 (12%)
Query: 98 NASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCS--VQGRPETGH 155
N ++ I +Q D G Y+C +N G ++ ++ +SV V+ + L S G
Sbjct: 1910 NGTLVIRKVQVQDRGQYMCTASN---LHGLDRMVVLLSVTVQQPQILASHYQDVTVYLGD 1966
Query: 156 TISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTTG--------ILVIGNLTNFEQG 207
TI++ CL A GTP+P W + R V + +P G L I + ++G
Sbjct: 1967 TIAMECL-AKGTPAPQISWIFPDRR----VWQTVSPVEGRITLHENRTLSIKEASFSDRG 2021
Query: 208 YYQCTAINRLGNSSCEIDL 226
Y+C A N G S I L
Sbjct: 2022 VYKCVASNAAGADSLAIRL 2040
Score = 39.3 bits (90), Expect = 0.006
Identities = 34/131 (25%), Positives = 60/131 (45%), Gaps = 14/131 (10%)
Query: 98 NASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPET---- 153
N ++ I ++ P DSG Y C N +G + + ++V + + T
Sbjct: 2104 NGTLYIRNLAPKDSGRYECVAAN---LVGSARRTVQLNVQRAAANARITGTSPRRTDVRY 2160
Query: 154 GHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNP-----TTGILVIGNLTNFEQGY 208
G T+ L C SA G P P W +L + ++ +F+ G LV+ ++T+ + G
Sbjct: 2161 GGTLKLDC-SASGDPWPRILW-RLPSKRMIDALFSFDSRIKVFANGTLVVKSVTDKDAGD 2218
Query: 209 YQCTAINRLGN 219
Y C A N++G+
Sbjct: 2219 YLCVARNKVGD 2229
Score = 38.1 bits (87), Expect = 0.014
Identities = 52/228 (22%), Positives = 91/228 (39%), Gaps = 36/228 (15%)
Query: 7 KVFLILSCLAGQVSVVQVTIPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWSFFHKKE 66
++ ++LS Q ++ D V V +G + + C+ T A + I W F ++
Sbjct: 1938 RMVVLLSVTVQQPQILASHYQD--VTVYLGDTIAMECLAKGTPAPQ----ISWIFPDRRV 1991
Query: 67 MEPISIYFSQGGQAVAIGQFKDRITGSNDPGNASITISHMQPADSGIYICDVNNPPDFLG 126
+ +S + RIT N +++I +D G+Y C +N G
Sbjct: 1992 WQTVS-------------PVEGRITLHE---NRTLSIKEASFSDRGVYKCVASNAA---G 2032
Query: 127 QNQGILNVSVLVKP----SKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLEGRDI 182
+ + + V P + L ++ P G +I + C +A P P W +G I
Sbjct: 2033 ADSLAIRLHVAALPPVIHQEKLENISLPP--GLSIHIHC-TAKAAPLPSVRWVLGDGTQI 2089
Query: 183 VPVK----ENFNPTTGILVIGNLTNFEQGYYQCTAINRLGNSSCEIDL 226
P + F G L I NL + G Y+C A N +G++ + L
Sbjct: 2090 RPSQFLHGNLFVFPNGTLYIRNLAPKDSGRYECVAANLVGSARRTVQL 2137
Score = 34.7 bits (78), Expect = 0.15
Identities = 39/144 (27%), Positives = 60/144 (41%), Gaps = 15/144 (10%)
Query: 98 NASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSK------PLCSVQGRP 151
+ ++ I Q +DSG Y C V N G+++ + + V V+P K P+ +V+
Sbjct: 2400 DGTLLIQKAQRSDSGNYTCLVRNS---AGEDRKTVWIHVNVQPPKINGNPNPITTVREIA 2456
Query: 152 ETGHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTT----GILVIGNLTNFEQG 207
G + C A G P+P W EG ++P N T G L I +L +
Sbjct: 2457 AGGSRKLIDC-KAEGIPTPRVLWAFPEG-VVLPAPYYGNRITVHGNGSLDIRSLRKSDSV 2514
Query: 208 YYQCTAINRLGNSSCEIDLTSSHP 231
C A N G + + LT P
Sbjct: 2515 QLVCMARNEGGEARLILQLTVLEP 2538
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 59.3 bits (142), Expect = 6e-09
Identities = 59/212 (27%), Positives = 88/212 (41%), Gaps = 36/212 (16%)
Query: 26 IPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWSFFHKKEMEPISIYFSQGGQAVAIGQ 85
+P+G V V VG VTL C+ A + S +W+ +
Sbjct: 3117 LPEGPVWVKVGKAVTLECVS----AGEPRSSARWTRISSTP-----------------AK 3155
Query: 86 FKDRITGSNDPGNASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSV---LVKPSK 142
+ R G D +A + IS +P+D+G Y+C N LG Q + V V + P
Sbjct: 3156 LEQRTYGLMD-SHAVLQISSAKPSDAGTYVCLAQNA---LGTAQKQVEVIVDTGAMAPGA 3211
Query: 143 PLCSVQGRP---ETGHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTTGILVIG 199
P + E GHT +L C SA G+P+P +W KL R +P + T L+I
Sbjct: 3212 PQVQAEEAELTVEAGHTATLRC-SATGSPAPTIHWSKL--RSPLPWQHRLEGDT--LIIP 3266
Query: 200 NLTNFEQGYYQCTAINRLGNSSCEIDLTSSHP 231
+ + G Y C A + G++ I L P
Sbjct: 3267 RVAQQDSGQYICNATSPAGHAEATIILHVESP 3298
Score = 50.1 bits (118), Expect = 3e-06
Identities = 50/212 (23%), Positives = 84/212 (39%), Gaps = 42/212 (19%)
Query: 16 AGQVSVVQVTIPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWSFFHKKEMEPISIYFS 75
AG VQVT ++G++V C V S ++W F
Sbjct: 3396 AGSTPTVQVT--PQLETKSIGASVEFHC----AVPSDRGTQLRW--------------FK 3435
Query: 76 QGGQAVAIGQFKDRITGSNDPGNASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVS 135
+GGQ +D + + I ++ + G YIC + P G+ Q +
Sbjct: 3436 EGGQLPPGHSVQDGV----------LRIQNLDQSCQGTYICQAHGP---WGKAQASAQLV 3482
Query: 136 VLVKPSKPLCSVQGRPET---GHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPT 192
+ PS L +++ +T GH + CL ALG P P W K+ G ++ +
Sbjct: 3483 IQALPSV-LINIRTSVQTVVVGHAVEFECL-ALGDPKPQVTWSKVGGH----LRPGIVQS 3536
Query: 193 TGILVIGNLTNFEQGYYQCTAINRLGNSSCEI 224
G++ I ++ + G Y+CTA N G + +
Sbjct: 3537 GGVVRIAHVELADAGQYRCTATNAAGTTQSHV 3568
Score = 44.7 bits (104), Expect = 1e-04
Identities = 39/149 (26%), Positives = 67/149 (44%), Gaps = 18/149 (12%)
Query: 79 QAVAIGQFKDRITGSNDPGNAS---------ITISHMQPADSGIYICDVNNPPDFLGQNQ 129
+ +A+G K ++T S G+ + I+H++ AD+G Y C N Q+
Sbjct: 3509 ECLALGDPKPQVTWSKVGGHLRPGIVQSGGVVRIAHVELADAGQYRCTATNAAGTT-QSH 3567
Query: 130 GILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENF 189
+L V L + S P + R G C+++ G P+P W KL+G + +
Sbjct: 3568 VLLLVQALPQISMPQ---EVRVPAGSAAVFPCIAS-GYPTPDISWSKLDGS----LPPDS 3619
Query: 190 NPTTGILVIGNLTNFEQGYYQCTAINRLG 218
+L++ ++ + G Y CTA NR G
Sbjct: 3620 RLENNMLMLPSVRPQDAGTYVCTATNRQG 3648
Score = 43.5 bits (101), Expect = 3e-04
Identities = 34/117 (29%), Positives = 50/117 (42%), Gaps = 15/117 (12%)
Query: 106 MQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLC-------SVQGRPETGHTIS 158
+QP+D+G+YIC N N + V PSKP+ S RP G ++
Sbjct: 1736 VQPSDAGVYICTCRN---LHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRP--GADVT 1790
Query: 159 LSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTTGILVIGNLTNFEQGYYQCTAIN 215
C + +P+ W +L + +FN GIL I N+ + G Y CT N
Sbjct: 1791 FICTAKSKSPAYTLVWTRLHNGKLPTRAMDFN---GILTIRNVQLSDAGTYVCTGSN 1844
Score = 42.7 bits (99), Expect = 6e-04
Identities = 57/243 (23%), Positives = 99/243 (40%), Gaps = 22/243 (9%)
Query: 53 EQLSIQWSFFHKKEMEPISIYFSQGGQAVAIGQFKDR---ITGSNDPGNASITISHMQPA 109
+ + I+ S H E + + + GQA A + R + + + + + + PA
Sbjct: 2925 QPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGSLPARHQTHGSQLRLHLVSPA 2984
Query: 110 DSGIYICDVNNPPDFLGQNQGILNVSVLVKPSK--------PLCSVQGRPET---GHTIS 158
DSG Y+C + P G Q + +V V PS+ P+ S+ T G S
Sbjct: 2985 DSGEYVCRAASGP---GPEQEA-SFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDAS 3040
Query: 159 LSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTTGILVIGNLTNFEQGYYQCTAINRLG 218
CL G +P+ K +++ + +P I+ I G Y+C A N G
Sbjct: 3041 FKCLIHDGA-APISLEWKTRNQELED-NVHISPNGSIITIVGTRPSNHGTYRCVASNAYG 3098
Query: 219 NSSCEIDLT-SSHPEVGIIVGALIGSLVGAAIIISVVCFARNKAKAKAKERNSKTIAELE 277
+ ++L+ P V ++ + VG A+ + V ++ A+ R S T A+LE
Sbjct: 3099 VAQSVVNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPRSSAR-WTRISSTPAKLE 3157
Query: 278 PMT 280
T
Sbjct: 3158 QRT 3160
Score = 42.0 bits (97), Expect = 0.001
Identities = 31/123 (25%), Positives = 53/123 (43%), Gaps = 7/123 (5%)
Query: 106 MQPADSGIYICDVNNPPDFLGQN--QGILNVSVLVKPSKPLCSVQGRPETGHTISLSCLS 163
++P D Y+C ++ GQ + +L+V P + + + G T+ L C +
Sbjct: 1923 VEPTDQAQYLCRAHSSA---GQQVARAVLHVHGGGGPRVQVSPERTQVHAGRTVRLYCRA 1979
Query: 164 ALGTPSPVYYWHKLEGRDIVPVKENFNPTTGILVIGNLTNFEQGYYQCTAINRLGNSSCE 223
A G PS W K EG + P + L+I +T + G+Y C A + G +
Sbjct: 1980 A-GVPSATITWRK-EGGSLPPQARSERTDIATLLIPAITTADAGFYLCVATSPAGTAQAR 2037
Query: 224 IDL 226
I +
Sbjct: 2038 IQV 2040
Score = 40.0 bits (92), Expect = 0.004
Identities = 45/190 (23%), Positives = 76/190 (40%), Gaps = 34/190 (17%)
Query: 32 NVTVGSNVTLICIYTTTVASREQLSIQWSFFHKKEMEPISIYFSQGGQAVAIGQFKDRIT 91
+V G++VT IC T + ++ W+ H ++ ++ F
Sbjct: 1782 SVRPGADVTFIC---TAKSKSPAYTLVWTRLHNGKLPTRAMDF----------------- 1821
Query: 92 GSNDPGNASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSV---Q 148
N +TI ++Q +D+G Y+C +N + Q L+V S P+ S+ Q
Sbjct: 1822 ------NGILTIRNVQLSDAGTYVCTGSN-MFAMDQGTATLHVQASGTLSAPVVSIHPPQ 1874
Query: 149 GRPETGHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTTGILVIGNLTNFEQGY 208
+ G C SA G+P+P W G + P K + GIL + + +Q
Sbjct: 1875 LTVQPGQLAEFRC-SATGSPTPTLEWTGGPGGQL-PAKAQIH--GGILRLPAVEPTDQAQ 1930
Query: 209 YQCTAINRLG 218
Y C A + G
Sbjct: 1931 YLCRAHSSAG 1940
Score = 36.6 bits (83), Expect = 0.039
Identities = 21/69 (30%), Positives = 35/69 (50%), Gaps = 7/69 (10%)
Query: 154 GHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTT----GILVIGNLTNFEQGYY 209
G T++ +C+ A+G P+P+ W G +P T+ G L+I ++ +QG Y
Sbjct: 421 GQTVTFTCV-AIGVPTPIINWRLNWGH--IPSHPRVTVTSEGGRGTLIIRDVKESDQGAY 477
Query: 210 QCTAINRLG 218
C A+N G
Sbjct: 478 TCEAMNARG 486
Score = 35.0 bits (79), Expect = 0.11
Identities = 56/230 (24%), Positives = 82/230 (35%), Gaps = 58/230 (25%)
Query: 16 AGQVSVVQVT----IPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWSFFHKKEMEPIS 71
AG V + VT I V G + L C+ VA + + W HK+
Sbjct: 2427 AGSVPALGVTPTVRIESSSSQVAEGQTLDLNCL----VAGQAHAQVTW---HKR------ 2473
Query: 72 IYFSQGGQAVAIGQFKDRITGSNDPGNASITISHMQPADSGIYICDVNNPPDFLGQNQGI 131
GG A + ++ GS + + + PADSG Y+C V + G
Sbjct: 2474 -----GGSLPA----RHQVHGSR------LRLLQVTPADSGEYVCRVVG-------SSGT 2511
Query: 132 LNVSVLVKPSKPLC--------------SVQGRPETGHTISLSCLSALGTPSPVYYWHKL 177
SVLV + L S GHT+ L+CL A P + W+K
Sbjct: 2512 QEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTI-TWYKR 2570
Query: 178 EGRDIVPVKENFNPTTGILVIGNLTNFEQGYYQCTAINRLGNSSCEIDLT 227
G +P + L I +T + G Y C N G+ + +T
Sbjct: 2571 GGS--LPSRHQI--VGSRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVT 2616
Score = 35.0 bits (79), Expect = 0.11
Identities = 77/364 (21%), Positives = 136/364 (37%), Gaps = 73/364 (20%)
Query: 24 VTIPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWSFFHKKEMEPISIYFSQGGQAVAI 83
V I ++ G + L C+ VAS+ +I W + +GG +
Sbjct: 2536 VRIESSSASLANGHTLDLNCL----VASQAPHTITW--------------YKRGGSLPS- 2576
Query: 84 GQFKDRITGSNDPGNASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKP 143
+ +I GS + I + PADSG Y+C V+N G + L V++ S
Sbjct: 2577 ---RHQIVGSR------LRIPQVTPADSGEYVCHVSNG---AGSRETSLIVTIQGSGSSH 2624
Query: 144 LCSVQG--RPET-------GHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTTG 194
+ SV R E+ G T+ L+C+ A P + W+K G +P + + +
Sbjct: 2625 VPSVSPPIRIESSSPTVVEGQTLDLNCVVA-RQPQAIITWYKRGGS--LPSRHQTHGSH- 2680
Query: 195 ILVIGNLTNFEQGYYQCTAINRLGNSSCEIDLTSSHPEVGIIVGALIGSLVGAAIIISVV 254
L + ++ + G Y C A N ID + + + A S G+++ I +
Sbjct: 2681 -LRLHQMSVADSGEYVCRANN-------NIDALEASIVISVSPSAGSPSAPGSSMPIRIE 2732
Query: 255 CFARNKAKAKAKERNSKTIAELEPMTKINPRGESEAMPREDATQLEVTLPSSIHETGPDT 314
+ + A+ + + N + + RG S LPS H+T
Sbjct: 2733 SSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGGS--------------LPSH-HQTRGSR 2777
Query: 315 IQEPDYEPKPTQEPAPEPAPGSEPMAVPDLDIELELEPETQSELEPEPEPEPESEPGVVV 374
++ P + E S P+ + + + +E S + P P P + +
Sbjct: 2778 LRLHHVSPADSGEYVCRVMGSSGPL---EASVLVTIEASGSSAVH---VPAPGGAPPIRI 2831
Query: 375 EPLS 378
EP S
Sbjct: 2832 EPSS 2835
Score = 33.9 bits (76), Expect = 0.26
Identities = 38/154 (24%), Positives = 60/154 (38%), Gaps = 25/154 (16%)
Query: 101 ITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVL----VKPSKPLCSVQGRP----- 151
+ + + PADSG Y+C V N G + + VSVL PS RP
Sbjct: 2102 LRLPQVSPADSGEYVCRVENGS---GPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEP 2158
Query: 152 -----ETGHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTTGILVIGNLTNFEQ 206
G T+ L+C+ G WHK G +P + + + +L + +T +
Sbjct: 2159 SSSHVAEGQTLDLNCV-VPGQAHAQVTWHKRGGS--LPARHQTHGS--LLRLHQVTPADS 2213
Query: 207 GYYQCTAINRLGNSSCEIDLTSSHPEVGIIVGAL 240
G Y C + G + +T E +I G +
Sbjct: 2214 GEYVCHVVGTSGPLEASVLVTI---EASVIPGPI 2244
Score = 33.5 bits (75), Expect = 0.33
Identities = 36/133 (27%), Positives = 53/133 (39%), Gaps = 25/133 (18%)
Query: 108 PADSGIYICDVNNPPDFLGQNQGILNVSVL-------------VKPSKPLCSVQGRPETG 154
PADSG Y+C V LG + L SVL V P+ + S + G
Sbjct: 2399 PADSGEYVCRV------LGSSVP-LEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEG 2451
Query: 155 HTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTTGILVIGNLTNFEQGYYQCTAI 214
T+ L+CL A G WHK G +P + + + L + +T + G Y C +
Sbjct: 2452 QTLDLNCLVA-GQAHAQVTWHKRGGS--LPARHQVHGSR--LRLLQVTPADSGEYVCRVV 2506
Query: 215 NRLGNSSCEIDLT 227
G + +T
Sbjct: 2507 GSSGTQEASVLVT 2519
Score = 30.0 bits (66), Expect = 3.7
Identities = 33/141 (23%), Positives = 57/141 (40%), Gaps = 21/141 (14%)
Query: 99 ASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVL--VKPSKPLCSVQGRPET--- 153
A++ I + AD+G Y+C +P G Q + V VL S P ++ +
Sbjct: 2008 ATLLIPAITTADAGFYLCVATSP---AGTAQARIQVVVLSASDASPPPVKIESSSPSVTE 2064
Query: 154 GHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTTGI----LVIGNLTNFEQGYY 209
G T+ L+C+ A G+ W++ G + P T + L + ++ + G Y
Sbjct: 2065 GQTLDLNCVVA-GSAHAQVTWYRRGG--------SLPPHTQVHGSRLRLPQVSPADSGEY 2115
Query: 210 QCTAINRLGNSSCEIDLTSSH 230
C N G I ++ H
Sbjct: 2116 VCRVENGSGPKEASITVSVLH 2136
Score = 29.3 bits (64), Expect = 6.3
Identities = 44/153 (28%), Positives = 56/153 (36%), Gaps = 25/153 (16%)
Query: 92 GSNDPGNAS-----ITISHMQPADSGIYICDVNNP-------PDFLGQNQ-GILNVSVLV 138
GS+ PG A+ + P DSG Y C V N L Q G L + +
Sbjct: 3336 GSSLPGRATARNELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIP 3395
Query: 139 KPSKPLCSVQGRPET---GHTISLSCL--SALGTPSPVYYWHKLEGRDIVPVKENFNPTT 193
S P V + ET G ++ C S GT W K EG + P +
Sbjct: 3396 AGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQ---LRWFK-EGGQLPP---GHSVQD 3448
Query: 194 GILVIGNLTNFEQGYYQCTAINRLGNSSCEIDL 226
G+L I NL QG Y C A G + L
Sbjct: 3449 GVLRIQNLDQSCQGTYICQAHGPWGKAQASAQL 3481
Score = 28.9 bits (63), Expect = 8.2
Identities = 36/149 (24%), Positives = 62/149 (41%), Gaps = 8/149 (5%)
Query: 118 VNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKL 177
V NP GQ N + LV P S+ + G + SL C G+P +YW +
Sbjct: 1658 VGNPSVQGGQCLPETNQAPLVVEVHPARSIVPQ---GGSHSLRC-QVSGSPPHYFYWSRE 1713
Query: 178 EGRDIVPVKENFNPTTGILVIGNLTNFEQGYYQCTA--INRLGNSSCEIDLTSSHPE-VG 234
+GR VP L ++ + G Y CT +++ S E+ +T + + +
Sbjct: 1714 DGRP-VPSGTQQRHQGSELHFPSVQPSDAGVYICTCRNLHQSNTSRAELLVTEAPSKPIT 1772
Query: 235 IIVGALIGSLVGAAIIISVVCFARNKAKA 263
+ V V ++ +C A++K+ A
Sbjct: 1773 VTVEEQRSQSVRPGADVTFICTAKSKSPA 1801
Score = 28.9 bits (63), Expect = 8.2
Identities = 27/92 (29%), Positives = 39/92 (42%), Gaps = 22/92 (23%)
Query: 67 MEPISIYFSQGG----QAVAIGQFKDRITGSNDPGNAS---------ITISHMQPADSGI 113
+EP S ++G + V GQ ++T GN + ++ + PADSG
Sbjct: 2831 IEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKRGGNLPARHQVHGPLLRLNQVSPADSGE 2890
Query: 114 YICDVNNPPDFLGQNQGILNVSVLV--KPSKP 143
Y C V + G L SVLV +PS P
Sbjct: 2891 YSCQVTG-------SSGTLEASVLVTIEPSSP 2915
>gi|38093645 myelin protein zero-like 3 [Homo sapiens]
Length = 235
Score = 57.4 bits (137), Expect = 2e-08
Identities = 34/99 (34%), Positives = 52/99 (52%), Gaps = 3/99 (3%)
Query: 28 DGFVNVTVGSNVTLICIYTTTVASREQLSIQWSFFHKKEMEPISIYFSQGGQ-AVAIGQF 86
D V VG + L C + +T ++L+I W++ +SI+ Q Q G F
Sbjct: 37 DAHVRGYVGEKIKLKCTFKSTSDVTDKLTIDWTYRPPSSSHTVSIFHYQSFQYPTTAGTF 96
Query: 87 KDRIT--GSNDPGNASITISHMQPADSGIYICDVNNPPD 123
+DRI+ G+ G+ASI+IS+ D+G + C V NPPD
Sbjct: 97 RDRISWVGNVYKGDASISISNPTIKDNGTFSCAVKNPPD 135
>gi|62000702 diacylglycerol kinase kappa [Homo sapiens]
Length = 1271
Score = 55.5 bits (132), Expect = 8e-08
Identities = 42/108 (38%), Positives = 51/108 (47%), Gaps = 18/108 (16%)
Query: 277 EPMTKINPRGESEAMPREDATQL-------EVTLPSSIHETGPDTIQEPDYEP--KPTQE 327
EP ++ P G E AT+L T P+S E P+ EP EP +P E
Sbjct: 56 EPCPELAP-GPCPEATSESATELYTEPTPEPATEPAS--EPAPEPATEPAPEPATEPAPE 112
Query: 328 PAPEPAPGSEPMAVPDLDIEL------ELEPETQSELEPEPEPEPESE 369
PAPEPA S P P+ +E EL PE EL PEP PEP +E
Sbjct: 113 PAPEPATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVTE 160
Score = 48.9 bits (115), Expect = 8e-06
Identities = 48/138 (34%), Positives = 60/138 (43%), Gaps = 20/138 (14%)
Query: 261 AKAKAKERNSKTIAEL--EPMTKINPRGESEAMPREDATQLEVTLPSSIHETGPDTIQEP 318
A E S++ EL EP + SE P E AT+ P E P+ EP
Sbjct: 62 APGPCPEATSESATELYTEPTPEPATEPASEPAP-EPATE---PAPEPATEPAPEPAPEP 117
Query: 319 DYE--PKPTQEPA----PEPAPGSEPMAVPDLDIELELEPETQSELEPE------PEPEP 366
E P+PT EPA PEPAP P P+L E EP T EL PE PE P
Sbjct: 118 ATESAPEPTPEPALESVPEPAPELTPEVAPELAPEPTPEPVT--ELAPEFCPEAAPEFRP 175
Query: 367 ESEPGVVVEPLSEDEKGV 384
P ++ P+ E+G+
Sbjct: 176 SPAPCLLQCPVDTRERGL 193
Score = 46.6 bits (109), Expect = 4e-05
Identities = 27/60 (45%), Positives = 32/60 (53%), Gaps = 4/60 (6%)
Query: 322 PKPTQEPAPEPAPGSEPMAVPDLDIELELEPETQSELEP--EPEPEPESEPGVVVEPLSE 379
P+P EP PE APG P A + EL EP + EP EP PEP +EP EP +E
Sbjct: 51 PEPIPEPCPELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEP--APEPATE 108
Score = 45.8 bits (107), Expect = 6e-05
Identities = 33/90 (36%), Positives = 40/90 (44%), Gaps = 14/90 (15%)
Query: 304 PSSIHETGPDTIQEPDYE------PKPTQEPA------PEPAPGSEPMAVPDLDIELELE 351
P + E P+ I EP E P+ T E A P P P +EP + P + E
Sbjct: 43 PPLLSEASPEPIPEPCPELAPGPCPEATSESATELYTEPTPEPATEPASEPAPEPATEPA 102
Query: 352 PETQSELEPEPEPEP--ESEPGVVVEPLSE 379
PE +E PEP PEP ES P EP E
Sbjct: 103 PEPATEPAPEPAPEPATESAPEPTPEPALE 132
Score = 40.0 bits (92), Expect = 0.004
Identities = 28/85 (32%), Positives = 38/85 (44%), Gaps = 10/85 (11%)
Query: 296 ATQLEVTLPSSIHETGPDTIQEPDYEPKPTQEPAPEPAP----GSEPMAVPDLDIEL--- 348
A + T P E ++ + P P P PAP PAP + P +P+ EL
Sbjct: 5 AAAAQGTAPPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPG 64
Query: 349 ---ELEPETQSELEPEPEPEPESEP 370
E E+ +EL EP PEP +EP
Sbjct: 65 PCPEATSESATELYTEPTPEPATEP 89
>gi|11386199 poliovirus receptor-related 3 [Homo sapiens]
Length = 549
Score = 54.3 bits (129), Expect = 2e-07
Identities = 49/171 (28%), Positives = 82/171 (47%), Gaps = 17/171 (9%)
Query: 10 LILSCLAGQVSVVQVTIPDGFVNVTVGSNVTLICIYTTTVASREQLSIQWSFFHKKEMEP 69
L+ S L G ++ + P V G NV+L C+ + I W H K +
Sbjct: 47 LLFSRLCGALAGPIIVEPH--VTAVWGKNVSLKCLIEVNETITQ---ISWEKIHGKSSQT 101
Query: 70 ISIYFSQGGQAVAIGQFKDRITGSNDPGN-ASITISHMQPADSGIYICDVNNPPDFLGQN 128
++++ Q G +V G+++ R+ N N A+IT+ ++ +DSG YIC P LG
Sbjct: 102 VAVHHPQYGFSVQ-GEYQGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVTFP--LGNA 158
Query: 129 QGILNVSVLVKPSKPLCSVQGRPET-----GHTISLSCLSALGTPSPVYYW 174
Q V+VLV+P+ L ++G P++ T++ C++A G P W
Sbjct: 159 QSSTTVTVLVEPTVSL--IKG-PDSLIDGGNETVAAICIAATGKPVAHIDW 206
>gi|38490688 immunoglobulin superfamily, member 10 [Homo sapiens]
Length = 2623
Score = 54.3 bits (129), Expect = 2e-07
Identities = 38/138 (27%), Positives = 68/138 (49%), Gaps = 14/138 (10%)
Query: 98 NASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPET---- 153
+ ++ + ++ D G Y C +NP GQ+ ++ + V+ P P+ Q R
Sbjct: 1802 DGTLVLHNLSIYDRGFYKCVASNPG---GQDSLLVKIQVIAAP--PVILEQRRQVIVGTW 1856
Query: 154 GHTISLSCLSALGTPSPVYYWHKLEGRDIVPVK----ENFNPTTGILVIGNLTNFEQGYY 209
G ++ L C +A GTP P YW +G ++ P++ + F + G L I NL + ++G Y
Sbjct: 1857 GESLKLPC-TAKGTPQPSVYWVLSDGTEVKPLQFTNSKLFLFSNGTLYIRNLASSDRGTY 1915
Query: 210 QCTAINRLGNSSCEIDLT 227
+C A + G+ + LT
Sbjct: 1916 ECIATSSTGSERRVVMLT 1933
Score = 46.2 bits (108), Expect = 5e-05
Identities = 36/131 (27%), Positives = 62/131 (47%), Gaps = 12/131 (9%)
Query: 98 NASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPL--CSVQGRPETGH 155
N +++I ++ D G Y+C +N G + + +SV+ P + L + + +G
Sbjct: 1705 NGTLSIQRVEIQDRGQYLCSASN---LFGTDHLHVTLSVVSYPPRILERRTKEITVHSGS 1761
Query: 156 TISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFN-----PTTGILVIGNLTNFEQGYYQ 210
T+ L C A G PSP W L + +V + G LV+ NL+ +++G+Y+
Sbjct: 1762 TVELKC-RAEGRPSPTVTWI-LANQTVVSESSQGSRQAVVTVDGTLVLHNLSIYDRGFYK 1819
Query: 211 CTAINRLGNSS 221
C A N G S
Sbjct: 1820 CVASNPGGQDS 1830
Score = 43.9 bits (102), Expect = 2e-04
Identities = 38/142 (26%), Positives = 63/142 (44%), Gaps = 16/142 (11%)
Query: 98 NASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPET--GH 155
N S+ I + DSG+Y+C N +G + +++VS+ +KP+K R + G
Sbjct: 1998 NGSLFIGSVTEKDSGVYLCVARNK---MGDDLILMHVSLRLKPAKIDHKQYFRKQVLHGK 2054
Query: 156 TISLSCLSALGTPSPVYYWHKLEGRDI---VPVKENFNPTTGILVIGNLTNF-------E 205
+ C A G+P P W +G I + ++ + T + N T + E
Sbjct: 2055 DFQVDC-KASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKVGVAE 2113
Query: 206 QGYYQCTAINRLGNSSCEIDLT 227
+G Y C A N LG ++ LT
Sbjct: 2114 EGDYTCYAQNTLGKDEMKVHLT 2135
Score = 41.2 bits (95), Expect = 0.002
Identities = 40/133 (30%), Positives = 56/133 (42%), Gaps = 18/133 (13%)
Query: 98 NASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKP----SKPLCSVQGRPET 153
N ++ I D G YIC N +G + V ++ P ++P S+ R T
Sbjct: 2488 NGTLVIKEATAYDRGNYICKAQNS---VGHTLITVPVMIVAYPPRITNRPPRSIVTR--T 2542
Query: 154 GHTISLSCLSALGTPSPVYYW----HKL---EGRDIVPVKENFNPTTGILVIGNLTNFEQ 206
G L C+ ALG P P W H L ++ E + G LVI N +
Sbjct: 2543 GAAFQLHCV-ALGVPKPEITWEMPDHSLLSTASKERTHGSEQLH-LQGTLVIQNPQTSDS 2600
Query: 207 GYYQCTAINRLGN 219
G Y+CTA N LG+
Sbjct: 2601 GIYKCTAKNPLGS 2613
Score = 40.8 bits (94), Expect = 0.002
Identities = 31/131 (23%), Positives = 58/131 (44%), Gaps = 14/131 (10%)
Query: 98 NASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPET---- 153
N ++ I ++ +D G Y C + G + ++ +++ + + P + T
Sbjct: 1899 NGTLYIRNLASSDRGTYECIATSST---GSERRVVMLTMEERVTSPRIEAASQKRTEVNF 1955
Query: 154 GHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNP-----TTGILVIGNLTNFEQGY 208
G + L+C SA G P P W +L + +V + G L IG++T + G
Sbjct: 1956 GDKLLLNC-SATGEPKPQIMW-RLPSKAVVDQQHRVGSWIHVYPNGSLFIGSVTEKDSGV 2013
Query: 209 YQCTAINRLGN 219
Y C A N++G+
Sbjct: 2014 YLCVARNKMGD 2024
Score = 35.8 bits (81), Expect = 0.067
Identities = 34/130 (26%), Positives = 54/130 (41%), Gaps = 14/130 (10%)
Query: 98 NASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQG----RPET 153
N S IS D+G Y C N ++ + + +L KP+ + +
Sbjct: 2393 NGSFIISKTTREDAGKYRCAARNKVGYIEK------LVILEIGQKPVILTYAPGTVKGIS 2446
Query: 154 GHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFN---PTTGILVIGNLTNFEQGYYQ 210
G ++SL C+S G P P W G + + N G LVI T +++G Y
Sbjct: 2447 GESLSLHCVSD-GIPKPNIKWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNYI 2505
Query: 211 CTAINRLGNS 220
C A N +G++
Sbjct: 2506 CKAQNSVGHT 2515
Score = 34.3 bits (77), Expect = 0.20
Identities = 29/128 (22%), Positives = 57/128 (44%), Gaps = 11/128 (8%)
Query: 98 NASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLC----SVQGRPET 153
N ++ I +++ +DS +IC N G++ ++ + VL +P + + +
Sbjct: 2295 NGTLEIRNVRLSDSADFICVARNEG---GESVLVVQLEVLEMLRRPTFRNPFNEKIVAQL 2351
Query: 154 GHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFN---PTTGILVIGNLTNFEQGYYQ 210
G + +L+C S G P P W G +++ + G +I T + G Y+
Sbjct: 2352 GKSTALNC-SVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYR 2410
Query: 211 CTAINRLG 218
C A N++G
Sbjct: 2411 CAARNKVG 2418
Score = 33.9 bits (76), Expect = 0.26
Identities = 37/139 (26%), Positives = 54/139 (38%), Gaps = 15/139 (10%)
Query: 98 NASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLC-------SVQGR 150
N S+TI+ ++ DSG Y+C NP G + + + V+ KP PL +V
Sbjct: 2195 NGSLTINKVKLLDSGEYVCVARNPS---GDDTKMYKLDVVSKP--PLINGLYTNRTVIKA 2249
Query: 151 PETGHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPT---TGILVIGNLTNFEQG 207
H+ A GTPSP W + + T G L I N+ +
Sbjct: 2250 TAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSA 2309
Query: 208 YYQCTAINRLGNSSCEIDL 226
+ C A N G S + L
Sbjct: 2310 DFICVARNEGGESVLVVQL 2328
Score = 31.6 bits (70), Expect = 1.3
Identities = 33/115 (28%), Positives = 49/115 (42%), Gaps = 13/115 (11%)
Query: 110 DSGIYICDVNNPPDFLGQNQGILNVSV-LVKPSKPLCSVQGRPET---GHTISLSCLSAL 165
D+G+Y C +N D IL + +V+P G T G T+ L C S
Sbjct: 545 DTGVYHCISSNYDD-----ADILTYRITVVEPLVEAYQENGIHHTVFIGETLDLPCHST- 598
Query: 166 GTPSPVYYWHKLEGRDIV--PVKENFNPTTGILVIGNLTNFEQGYYQCTAINRLG 218
G P W + G +++ ++ G L I +T +QGYY+C A N G
Sbjct: 599 GIPDASISW-VIPGNNVLYQSSRDKKVLNNGTLRILQVTPKDQGYYRCVAANPSG 652
Score = 30.4 bits (67), Expect = 2.8
Identities = 19/68 (27%), Positives = 31/68 (45%), Gaps = 4/68 (5%)
Query: 164 ALGTPSPVYYWHKL-EGRDIVPVKENFNPTT---GILVIGNLTNFEQGYYQCTAINRLGN 219
A+G P P +W ++ G D+ K+N G L I + ++G Y C+A N G
Sbjct: 1672 AVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPNGTLSIQRVEIQDRGQYLCSASNLFGT 1731
Query: 220 SSCEIDLT 227
+ L+
Sbjct: 1732 DHLHVTLS 1739
Score = 29.6 bits (65), Expect = 4.8
Identities = 19/49 (38%), Positives = 24/49 (48%), Gaps = 7/49 (14%)
Query: 98 NASITISHMQPADSGIYICDVNNPP--DFLGQNQGILNVSVLVKPSKPL 144
N ++ I + P D G Y C NP DFL I VSV +K +PL
Sbjct: 627 NGTLRILQVTPKDQGYYRCVAANPSGVDFL-----IFQVSVKMKGQRPL 670
>gi|13376852 CD276 antigen isoform b [Homo sapiens]
Length = 316
Score = 53.9 bits (128), Expect = 2e-07
Identities = 66/284 (23%), Positives = 114/284 (40%), Gaps = 51/284 (17%)
Query: 14 CLAGQVSVVQVTIPDGFVNVTVGSNVTLICIYTTTVA-SREQLSIQWSFFHKKEMEPISI 72
CL G ++V +P+ V VG++ TL C ++ S QL++ W K++
Sbjct: 24 CLTG---ALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFA 80
Query: 73 YFSQGGQAVA--IGQFKDRITGSNDPGNASITISHMQPADSGIYICDVNNPPDFLGQNQG 130
G A A F D + GNAS+ + ++ AD G + C V + DF
Sbjct: 81 EGQDQGSAYANRTALFPDLLA----QGNASLRLQRVRVADEGSFTCFV-SIRDF---GSA 132
Query: 131 ILNVSVLVKPSKPLCSVQGRPE--TGHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKEN 188
+++ V SKP +++ + G T++++C S G P +W +G
Sbjct: 133 AVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQG--------- 183
Query: 189 FNPTTGILVIGNLTNFEQGYYQCTAINRL-----GNSSC-------------EIDLTSS- 229
P TG + + N EQG + ++ R+ G SC + +T
Sbjct: 184 -VPLTGNVTTSQMAN-EQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQP 241
Query: 230 ---HPEVGIIVGALIGSLVGAAIIISVVCFARNKAKAKAKERNS 270
PE + L L+ + ++ VC+ K K +E N+
Sbjct: 242 MTFPPEALWVTVGLSVCLIALLVALAFVCW--RKIKQSCEEENA 283
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 53.5 bits (127), Expect = 3e-07
Identities = 73/286 (25%), Positives = 121/286 (42%), Gaps = 44/286 (15%)
Query: 68 EPISI-YFSQGGQAVAIGQFKDRITGSNDPGNASITISHMQPADSGIYICDVNNPPDFLG 126
EPIS+ +F G+ V + D I S A++ S ++PA++G Y C + N G
Sbjct: 7519 EPISVVWFKDKGEIV---RESDNIWISYSENIATLQFSRVEPANAGKYTCQIKND---AG 7572
Query: 127 QNQGILNVSVLVKPSKPLCSVQGRPE-----TGHTISLSCLSALGTPSPVYYWHKLEGRD 181
+ +SVL +P V+ +PE TG T +L C A GTP W K +G++
Sbjct: 7573 MQECFATLSVL----EPATIVE-KPESIKVTTGDTCTLECTVA-GTPELSTKWFK-DGKE 7625
Query: 182 IVPVKEN----FNPTTGILVIGNLTNFEQGYYQCTAINRLGNSSCEIDLTSSHPEVGIIV 237
+ + FN +G+ +I N+ + G Y N +G SC L S V
Sbjct: 7626 LTSDNKYKISFFNKVSGLKII-NVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSF 7684
Query: 238 GALI---GSLVGAAII----------ISVVCFARNKAKAKAKERNSKTIAELEPMTKINP 284
+ L G++++ ISV F + ++ + T+ + +N
Sbjct: 7685 TRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQT-TLTDNTCALTVNM 7743
Query: 285 RGESEAMPREDATQLEVTLPSSIHETGPDTIQEPDYEPKPTQEPAP 330
ES++ D T + + S + P T++EP P Q+P P
Sbjct: 7744 LEESDS---GDYTCIATNMAGSDECSAPLTVREP---PSFVQKPDP 7783
Score = 43.1 bits (100), Expect = 4e-04
Identities = 55/231 (23%), Positives = 96/231 (41%), Gaps = 33/231 (14%)
Query: 49 VASREQLSIQWSFFHKKEMEPISIYFSQGGQAVAIG-QFKDRITGSNDPGNASITISHMQ 107
V + ++Q F KE I+ + + GQ + +G ++K +T + + + I +
Sbjct: 4590 VTQGDPATLQVKFSGTKE---ITAKWFKDGQELTLGSKYKISVTDTV----SILKIISTE 4642
Query: 108 PADSGIYICDVNNPPDFLGQNQGILNVSVLVKPS-----KPLCSVQGRPETGHTISLSCL 162
DSG Y +V N I + +++ PS K + S++G I L C+
Sbjct: 4643 KKDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGS-----FIDLECI 4697
Query: 163 SALGTPSPVYYWHKLEGRDIVP---VKENFNPTTGILVIGNLTNFEQGYYQCTAINRLGN 219
A P + W K + ++I K +F+ T L I L + G Y C+A N+ G+
Sbjct: 4698 VAGSHPISIQ-WFK-DDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGH 4755
Query: 220 SSCEIDLTSSHP----------EVGIIVGALIGSLVGAAIIISVVCFARNK 260
+ C LT P +V + +LVG +++ F NK
Sbjct: 4756 NQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNK 4806
Score = 43.1 bits (100), Expect = 4e-04
Identities = 55/209 (26%), Positives = 87/209 (41%), Gaps = 28/209 (13%)
Query: 66 EMEPISIYFSQGGQAV----AIGQFKDRITGSNDP------GNASITISHMQP------- 108
+++P+SI G A G RIT S D GN +IT P
Sbjct: 6274 DIKPVSIDVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKV 6333
Query: 109 --ADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRP--ETGHTISLSCLSA 164
DSG Y C N +G++ +SV +P K + ++ + G +I L C +
Sbjct: 6334 GKGDSGQYTCQATND---VGKDMCSAQLSVK-EPPKFVKKLEASKVAKQGESIQLECKIS 6389
Query: 165 LGTPSPVYYWHKLEGRDIVPVKEN--FNPTTGILVIGNLTNFEQGYYQCTAINRLGNSSC 222
G+P W + + K N F + +L I + + G Y C A N +G++SC
Sbjct: 6390 -GSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASC 6448
Query: 223 EIDLTSSHPEVGIIVGALIGSLVGAAIII 251
LT P V + +G+L G+ +I+
Sbjct: 6449 STALTVKAPPVFTQKPSPVGALKGSDVIL 6477
Score = 41.6 bits (96), Expect = 0.001
Identities = 36/147 (24%), Positives = 59/147 (40%), Gaps = 21/147 (14%)
Query: 95 DPGNASITISHMQPADSGIYICDVNNPPDFLGQNQGIL--NVSVLVKPSKPLCSVQGRPE 152
D + S+ + + DSG YIC ++N + +K P+ ++
Sbjct: 4819 DDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKEPPQFIKKPSPVLVLRN--- 4875
Query: 153 TGHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTTGILVIGNLTNFE------- 205
G + + C GTP W+ L+G +I ++++ GI I L F+
Sbjct: 4876 -GQSTTFEC-QITGTPKIRVSWY-LDGNEITAIQKH-----GISFIDGLATFQISGARVE 4927
Query: 206 -QGYYQCTAINRLGNSSCEIDLTSSHP 231
G Y C A N G +SC I+L P
Sbjct: 4928 NSGTYVCEARNDAGTASCSIELKVKEP 4954
Score = 41.2 bits (95), Expect = 0.002
Identities = 44/181 (24%), Positives = 74/181 (40%), Gaps = 23/181 (12%)
Query: 63 HKKEMEPISIYFSQGGQAVAIGQFKDRITGSNDPGNASITISHMQPADSGIYICDVNNPP 122
H + EPI I + + G+ + + DR + S G A + + + ADSG Y+C +N
Sbjct: 8368 HVQGSEPIRIQWLKAGREI---KPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASN-- 8422
Query: 123 DFLGQNQGILNVSV----LVKPSKPLCSVQGR------PETGHTISLSCLSAL----GTP 168
G + V++ V P+ +V GR P++ + + + + G P
Sbjct: 8423 -VAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDP 8481
Query: 169 SPVYYWHKLEGRDIVPVKENFNPTTG---ILVIGNLTNFEQGYYQCTAINRLGNSSCEID 225
P W K + R + F G L I + T + G Y+C A N G ++
Sbjct: 8482 IPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVN 8541
Query: 226 L 226
L
Sbjct: 8542 L 8542
Score = 40.8 bits (94), Expect = 0.002
Identities = 59/258 (22%), Positives = 108/258 (41%), Gaps = 37/258 (14%)
Query: 99 ASITISHMQPADSGIYICDVNNPPDFLGQNQG---ILNVSVLVKPSKPLCSVQGRPETGH 155
A++ + +PA++G YIC + N + +N +L +V+V+ + P+ G
Sbjct: 5666 ATLQFAKAEPANAGKYICQIKNDGG-MRENMATLMVLEPAVIVEKAGPMTVT-----VGE 5719
Query: 156 TISLSCLSALGTPSPVYYWHKLEGRDIVPVKEN----FNPTTGILVIGNLTNFEQGYYQC 211
T +L C A GTP W+K +G+ + +++ +N + + ++ ++ + G Y
Sbjct: 5720 TCTLECKVA-GTPELSVEWYK-DGKLLTSSQKHKFSFYNKISSLRIL-SVERQDAGTYTF 5776
Query: 212 TAINRLGNSSCEI-----------DLTSSHPEVGIIVGA--LIGSLVGAAIIISVVCFAR 258
N +G SSC T G ++GA ++ V + ISV F
Sbjct: 5777 QVQNNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWF-H 5835
Query: 259 NKAKAKAKERNSKTIAELEPMTKINPRGESEAMPREDATQLEVTLPSSIHETGPDTIQEP 318
K K + + T ++ ++N S+ + T + + S T+QEP
Sbjct: 5836 EKTKIVSGAKYQTTFSDNVCTLQLNSLDSSD---MGNYTCVAANVAGSDECRAVLTVQEP 5892
Query: 319 DYEPKPTQEPAP-EPAPG 335
P +EP P E PG
Sbjct: 5893 ---PSFVKEPEPLEVLPG 5907
Score = 40.4 bits (93), Expect = 0.003
Identities = 39/145 (26%), Positives = 60/145 (41%), Gaps = 34/145 (23%)
Query: 99 ASITISHMQPADSGIYICDVNN-----------------PPDFLGQNQGILNVSVLVKPS 141
+S+ I Q D G Y C +N PP FL + + + + + K +
Sbjct: 3511 SSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSL--TTFVGKAA 3568
Query: 142 KPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTTGILVIGNL 201
K +C+V G P TI +AL +PSP + E + I L + NL
Sbjct: 3569 KFICTVTGTPVI-ETIWQKDGAAL-SPSPNWRISDAENKHI-------------LELSNL 3613
Query: 202 TNFEQGYYQCTAINRLGNSSCEIDL 226
T ++G Y C A N+ G C+ +L
Sbjct: 3614 TIQDRGVYSCKASNKFGADICQAEL 3638
Score = 40.4 bits (93), Expect = 0.003
Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Query: 152 ETGHTISLSCLSALGTPSPVYYWHKLEGRDIVP---VKENFNPTTGILVIGNLTNFEQGY 208
+ G TI L+ +S LG P P W K G+DI P + PT+ +L I T + G
Sbjct: 20391 KAGDTIVLNAISILGKPLPKSSWSK-AGKDIRPSDITQITSTPTSSMLTIKYATRKDAGE 20449
Query: 209 YQCTAINRLGNSSCEIDLT 227
Y TA N G + +T
Sbjct: 20450 YTITATNPFGTKVEHVKVT 20468
Score = 40.0 bits (92), Expect = 0.004
Identities = 52/230 (22%), Positives = 92/230 (40%), Gaps = 28/230 (12%)
Query: 69 PISIYFSQGGQAVAIGQFKDRITGSNDPGNASITISHMQPADSGIYICDVNNPPDFLGQN 128
PIS+ + Q G + G + S ++ +S ++P+D+GIY C N G +
Sbjct: 6769 PISVGWFQDGNEIVSGP---KCQSSFSENVCTLNLSLLEPSDTGIYTCVAAN---VAGSD 6822
Query: 129 QGILNVSVLVKPSKPLCSVQGRPETGHTI---SLSCLSAL-GTPSPVYYWHKLEGRDIVP 184
+ ++V PS + P++ + SL+ S + GTP W K R++VP
Sbjct: 6823 ECSAVLTVQEPPS-----FEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFK-GSRELVP 6876
Query: 185 VKE---NFNPTTGILVIGNLTNFEQGYYQCTAINRLGNSSCEIDLTSSHPEVGIIVGALI 241
+ + L + + E G Y C N G++SC L P + A
Sbjct: 6877 GESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLADF 6936
Query: 242 GSLVGAAIIISV---------VCFARNKAKAKAKERNSKTIAELEPMTKI 282
G+ I++ V + +++ ER S T+ E + +I
Sbjct: 6937 SVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEI 6986
Score = 39.7 bits (91), Expect = 0.005
Identities = 46/176 (26%), Positives = 75/176 (42%), Gaps = 24/176 (13%)
Query: 66 EMEPISIYFSQGGQAVAIGQ-----FKDRITGSNDPGNASITISHMQPADSGIYICDVNN 120
E +++ +S+ GQ + G+ F+D+I A++ I + DSG Y+C +N
Sbjct: 3669 EDRKVTVTWSKDGQKLPPGKDYKICFEDKI--------ATLEIPLAKLKDSGTYVCTASN 3720
Query: 121 PPDFLGQNQGILNVSVLVKPS---KPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHK- 176
G + V+V PS K S P G + L C G+P W K
Sbjct: 3721 EA---GSSSCSATVTVREPPSFVKKVDPSYLMLP--GESARLHC-KLKGSPVIQVTWFKN 3774
Query: 177 -LEGRDIVPVKENFNPTTGILVIGNLTNFEQGYYQCTAINRLGNSSCEIDLTSSHP 231
E + V+ F + IL I ++ + G Y C A+N +G+ SC ++ P
Sbjct: 3775 NKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEP 3830
Score = 39.7 bits (91), Expect = 0.005
Identities = 36/140 (25%), Positives = 56/140 (40%), Gaps = 16/140 (11%)
Query: 99 ASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPET--GHT 156
A I ++++ DSG +IC+ NP + V+VK S ET
Sbjct: 5479 AVIQMNNLSTEDSGDFICEAQNP-----AGSTSCSTKVIVKEPPVFSSFPPIVETLKNAE 5533
Query: 157 ISLSCLSALGTPSPVYYWHK-----LEGRDIVPVKENFNPTTGILVIGNLTNFEQGYYQC 211
+SL C GTP W+K + +NF+ + IL N+ + G Y C
Sbjct: 5534 VSLEC-ELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHIL---NVDTSDIGEYHC 5589
Query: 212 TAINRLGNSSCEIDLTSSHP 231
A N +G+ +C + P
Sbjct: 5590 KAQNEVGSDTCVCTVKLKEP 5609
Score = 39.7 bits (91), Expect = 0.005
Identities = 38/157 (24%), Positives = 60/157 (38%), Gaps = 13/157 (8%)
Query: 69 PISIYFSQGGQAVAIGQFKDRITGSNDPGNASITISHMQPADSGIYICDVNNPP--DFLG 126
PIS+ + + G + + + +T + I + D+G Y C++ N D G
Sbjct: 6014 PISVTWKKDGFNITTSEKCNIVTTEK---TCILEILNSTKRDAGQYSCEIENEAGRDVCG 6070
Query: 127 QNQGILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLEG--RDIVP 184
L V +PL G ++SL C A GTP W+K + R
Sbjct: 6071 ALVSTLEPPYFVTELEPL-----EAAVGDSVSLQCQVA-GTPEITVSWYKGDTKLRPTPE 6124
Query: 185 VKENFNPTTGILVIGNLTNFEQGYYQCTAINRLGNSS 221
+ F LV + + G Y C A N +G +S
Sbjct: 6125 YRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTAS 6161
Score = 39.7 bits (91), Expect = 0.005
Identities = 42/163 (25%), Positives = 68/163 (41%), Gaps = 16/163 (9%)
Query: 99 ASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPE---TGH 155
A +TI+ DSG YIC+ +N G + ++ VK + P+ + + P G
Sbjct: 6420 ALLTINEASAEDSGDYICEAHN-----GVGDASCSTALTVK-APPVFTQKPSPVGALKGS 6473
Query: 156 TISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTTG----ILVIGNLTNFEQGYYQC 211
+ L C GTP W K R V + F T+ L I NL + G Y C
Sbjct: 6474 DVILQC-EISGTPPFEVVWVK--DRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHC 6530
Query: 212 TAINRLGNSSCEIDLTSSHPEVGIIVGALIGSLVGAAIIISVV 254
A N +G+ +C + P + + +L+G A+ + +
Sbjct: 6531 KATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAI 6573
Score = 39.3 bits (90), Expect = 0.006
Identities = 53/224 (23%), Positives = 80/224 (35%), Gaps = 29/224 (12%)
Query: 13 SCLAGQVSVVQVTIPDGFVN--VTVGSNVTLICIYTTTVASREQLSIQWSFFHKKEMEPI 70
SC A V V +P F G + CI VA +S+ W F K ++
Sbjct: 5786 SCTA-VVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAW-FHEKTKIVSG 5843
Query: 71 SIYFSQGGQAVAIGQFKDRITGSNDPGNASITISHMQPADSGIYICDVNNPPDFLGQNQG 130
+ Y + V Q S+D GN + +++ +D + V PP F
Sbjct: 5844 AKYQTTFSDNVCTLQLNS--LDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSF------ 5895
Query: 131 ILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKE--- 187
VK +PL + G+ T ++ GTP W + R++V
Sbjct: 5896 -------VKEPEPLEVLPGKNVTFTSV------IRGTPPFKVNWFR-GARELVKGDRCNI 5941
Query: 188 NFNPTTGILVIGNLTNFEQGYYQCTAINRLGNSSCEIDLTSSHP 231
F T L + N+ + G Y C N G +SC L P
Sbjct: 5942 YFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEP 5985
Score = 39.3 bits (90), Expect = 0.006
Identities = 51/207 (24%), Positives = 81/207 (39%), Gaps = 33/207 (15%)
Query: 31 VNVTVGSNVTLICIYTTTVASREQLSIQWSFFHKKEMEPISIYFSQGGQAVAIGQFKDRI 90
+ VT G+ L C+ T T +LS +W F G + A K I
Sbjct: 6654 MTVTTGNPFALECVVTGT----PELSAKW--------------FKDGRELSA--DSKHHI 6693
Query: 91 TGSNDPGNASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSV---LVKPSKPLCSV 147
T N + I + M +D G+Y +V N +G++ ++V V +V PS
Sbjct: 6694 TFINKVASLKIPCAEM--SDKGLYSFEVKNS---VGKSNCTVSVHVSDRIVPPSFIRKLK 6748
Query: 148 QGRPETGHTISLSCLSALGTPSPVYYWHKLEGRDIVP---VKENFNPTTGILVIGNLTNF 204
G ++ L C + P V ++ +G +IV + +F+ L + L
Sbjct: 6749 DVNAILGASVVLECRVSGSAPISVGWFQ--DGNEIVSGPKCQSSFSENVCTLNLSLLEPS 6806
Query: 205 EQGYYQCTAINRLGNSSCEIDLTSSHP 231
+ G Y C A N G+ C LT P
Sbjct: 6807 DTGIYTCVAANVAGSDECSAVLTVQEP 6833
Score = 39.3 bits (90), Expect = 0.006
Identities = 60/251 (23%), Positives = 102/251 (40%), Gaps = 37/251 (14%)
Query: 99 ASITISHMQPADSGIYICDVNNPPDFLGQNQG--ILNVSVLVKPSKPLCSVQGRPETGHT 156
A + + ++ DSG Y C+ +N + + + K P+ +++G
Sbjct: 7361 AVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLKGAD----- 7415
Query: 157 ISLSCLSALGTPSPVYYWHK-----LEGRDIVPVKENFNPTTGILVIGNLTNFEQGYYQC 211
+ L C GTP W+K G+ + ENF + IL N+ + G YQC
Sbjct: 7416 VHLEC-ELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHIL---NVDAADIGEYQC 7471
Query: 212 TAINRLGNSSCEIDLTSSHP--------EVGIIVG--ALIGSLVGAAIIISVVCFARNKA 261
A N +G+ +C + P ++ +VG + + + A ISVV F ++K
Sbjct: 7472 KATNDVGSDTCVGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWF-KDKG 7530
Query: 262 KAKAKERN-----SKTIAELEPMTKINP--RGESEAMPREDATQLEVTLPSSIHETGPDT 314
+ + N S+ IA L+ +++ P G+ + DA E S+ E P T
Sbjct: 7531 EIVRESDNIWISYSENIATLQ-FSRVEPANAGKYTCQIKNDAGMQECFATLSVLE--PAT 7587
Query: 315 IQEPDYEPKPT 325
I E K T
Sbjct: 7588 IVEKPESIKVT 7598
Score = 38.9 bits (89), Expect = 0.008
Identities = 54/213 (25%), Positives = 81/213 (38%), Gaps = 41/213 (19%)
Query: 29 GFVNVTVGSNVTLICIYTTTVASREQLSIQWSFFHKKEMEPISIYFSQGGQAVAIGQFKD 88
G + VTVG TL C VA +LS++W K FS F +
Sbjct: 5711 GPMTVTVGETCTLEC----KVAGTPELSVEWYKDGKLLTSSQKHKFS----------FYN 5756
Query: 89 RITGSNDPGNASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSK---PLC 145
+I+ S+ I ++ D+G Y V N N G + + +V S P
Sbjct: 5757 KIS--------SLRILSVERQDAGTYTFQVQN-------NVGKSSCTAVVDVSDRAVPPS 5801
Query: 146 SVQGRPETGHTISLSCLS----ALGTPSPVYYWHKLEGRDIVP---VKENFNPTTGILVI 198
+ TG + SC+ A +P V ++H E IV + F+ L +
Sbjct: 5802 FTRRLKNTGGVLGASCILECKVAGSSPISVAWFH--EKTKIVSGAKYQTTFSDNVCTLQL 5859
Query: 199 GNLTNFEQGYYQCTAINRLGNSSCEIDLTSSHP 231
+L + + G Y C A N G+ C LT P
Sbjct: 5860 NSLDSSDMGNYTCVAANVAGSDECRAVLTVQEP 5892
Score = 38.9 bits (89), Expect = 0.008
Identities = 44/163 (26%), Positives = 62/163 (38%), Gaps = 13/163 (7%)
Query: 69 PISIYFSQGGQAVAIGQFKDRITGSNDPGNASITISHMQPADSGIYICDVNNPP--DFLG 126
PIS+ + + G V Q R + +A + I D+G Y C + N D
Sbjct: 7896 PISVTWKKNGINVTPSQ---RCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCS 7952
Query: 127 QNQGILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLEG--RDIVP 184
IL VK +P+ + G + SL C A GTP W+K + R
Sbjct: 7953 AQILILEPPYFVKQLEPV-----KVSVGDSASLQCQLA-GTPEIGVSWYKGDTKLRPTTT 8006
Query: 185 VKENFNPTTGILVIGNLTNFEQGYYQCTAINRLGNSSCEIDLT 227
K +F LV + + G Y C A N +G S LT
Sbjct: 8007 YKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLT 8049
Score = 37.0 bits (84), Expect = 0.030
Identities = 50/207 (24%), Positives = 86/207 (41%), Gaps = 32/207 (15%)
Query: 76 QGGQAVAIGQFKDRITGSNDPGN---------ASITISHMQPADSGIYICDVNNPPDFLG 126
+G Q +++ KDR + N A++ + + ++SG YIC + N
Sbjct: 6575 EGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKN------ 6628
Query: 127 QNQGILNVSVLVKPSKPLCSVQGRPE-----TGHTISLSCLSALGTPSPVYYWHKLEGRD 181
+ G+ S ++ +P ++ +PE TG+ +L C+ GTP W K +GR+
Sbjct: 6629 -DAGMRECSAVLTVLEPARIIE-KPEPMTVTTGNPFALECV-VTGTPELSAKWFK-DGRE 6684
Query: 182 IVPVKEN---FNPTTGILVIGNLTNFEQGYYQCTAINRLGNSSCEIDLTSSHPEVGIIVG 238
+ ++ F L I ++G Y N +G S+C + S H I+
Sbjct: 6685 LSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTV---SVHVSDRIVPP 6741
Query: 239 ALIGSL--VGAAIIISVVCFARNKAKA 263
+ I L V A + SVV R A
Sbjct: 6742 SFIRKLKDVNAILGASVVLECRVSGSA 6768
Score = 36.6 bits (83), Expect = 0.039
Identities = 34/129 (26%), Positives = 50/129 (38%), Gaps = 11/129 (8%)
Query: 253 VVCFARNKAKAKAKERNSKTIAELEPMTKINPRGESEAMPREDATQLEVTLPSSIHETGP 312
V F + KA K E + K I +P TK+ PR E A E ++ V
Sbjct: 10430 VEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVE---------- 10479
Query: 313 DTIQEPDYEPKPTQEPAPEPAPGSEPMAVPDLDIELELEPETQSELEPEPEPEPESEPGV 372
+ ++ P+ EP+ PE P E + + + +PE PE E E V
Sbjct: 10480 EKVRVPE-EPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKV 10538
Query: 373 VVEPLSEDE 381
V P + E
Sbjct: 10539 PVPPPKKPE 10547
Score = 36.6 bits (83), Expect = 0.039
Identities = 38/147 (25%), Positives = 56/147 (38%), Gaps = 20/147 (13%)
Query: 260 KAKAKAKERNSKTIAELEPMTKIN-PRGESEA---MPREDATQLEVTLPSSIHETGPDTI 315
KA K K + E +T + P GE + +P E + S+ P+
Sbjct: 10901 KAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEE- 10959
Query: 316 QEPDYEPKPTQE------PAPEPAPGSEPMAVPDLDIELELEPETQSELE---------P 360
+EP EPK ++ P P P E + VP + PE E P
Sbjct: 10960 EEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAP 11019
Query: 361 EPEPEPESEPGVVVEPLSEDEKGVVKA 387
EP+P+PE+E + P E E + A
Sbjct: 11020 EPKPKPEAEVKTIKPPPVEPEPTPIAA 11046
Score = 36.2 bits (82), Expect = 0.051
Identities = 42/163 (25%), Positives = 70/163 (42%), Gaps = 11/163 (6%)
Query: 68 EPISIYFSQGGQAVAIGQFKDRITGSNDPGNASITISHMQPADSGIYICDVNNPPDFLGQ 127
EPIS+ + +G Q V K +++ SN G A + I +Q + G Y C N
Sbjct: 3951 EPISVTWMKG-QEVIREDGKIKMSFSN--GVAVLIIPDVQISFGGKYTCLAENEAG---- 4003
Query: 128 NQGILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKE 187
+Q + ++ +P+K + + T + + GTP W+K +GR +V K+
Sbjct: 4004 SQTSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVAGTPELKPKWYK-DGRPLVASKK 4062
Query: 188 ---NFNPTTGILVIGNLTNFEQGYYQCTAINRLGNSSCEIDLT 227
+F L + + G Y N +G+SSCE T
Sbjct: 4063 YRISFKNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFT 4105
Score = 36.2 bits (82), Expect = 0.051
Identities = 31/139 (22%), Positives = 57/139 (41%), Gaps = 9/139 (6%)
Query: 99 ASITISHMQPADSGIYICDVNN--PPDFLGQNQGILNVSVLVKPSKPLCSVQGRPETGHT 156
A++T+ + D+G Y C +N D G+ +K +P V+ T +
Sbjct: 7267 ATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEPPRFIKKLEPSRIVKQDEFTRYE 7326
Query: 157 ISLSCLSALGTPSPVYYWHK--LEGRDIVPVKENFNPTTGILVIGNLTNFEQGYYQCTAI 214
+ G+P W+K E ++ + +F + +L + NL+ + G Y C A
Sbjct: 7327 CKIG-----GSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAH 7381
Query: 215 NRLGNSSCEIDLTSSHPEV 233
N G++S L P +
Sbjct: 7382 NAAGSASSSTSLKVKEPPI 7400
Score = 35.0 bits (79), Expect = 0.11
Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 11/85 (12%)
Query: 301 VTLPSSIHETGPDTIQEPDYEPKPTQEPAPE---PAPGSE-------PMAVPDLDIELEL 350
V +P P+ +EP+ E P +E APE P P +E P AVP+ ++
Sbjct: 10790 VPVPERAESPPPEVYEEPE-EIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIP 10848
Query: 351 EPETQSELEPEPEPEPESEPGVVVE 375
E + +PE P E EP V+E
Sbjct: 10849 EKKVPVIKKPEAPPPKEPEPEKVIE 10873
Score = 35.0 bits (79), Expect = 0.11
Identities = 21/65 (32%), Positives = 31/65 (47%), Gaps = 8/65 (12%)
Query: 166 GTPSPVYYWHKLEG----RDIVPVKENFNPTTGILVIGNLTNFEQGYYQCTAINRLGNSS 221
G P P W K EG R + V +F +LVI N+T F+ G Y T N G+ +
Sbjct: 25133 GRPEPEVKWEKAEGILTDRAQIEVTSSFT----MLVIDNVTRFDSGRYNLTLENNSGSKT 25188
Query: 222 CEIDL 226
+++
Sbjct: 25189 AFVNV 25193
Score = 34.7 bits (78), Expect = 0.15
Identities = 36/167 (21%), Positives = 70/167 (41%), Gaps = 13/167 (7%)
Query: 69 PISI-YFSQGGQAVAIGQFKDRITGSNDPGNASITISHMQPADSGIYICDVNNPPDFLGQ 127
PIS+ +F +G + + +++ +T + ++T++ ++ +DSG Y C N G
Sbjct: 7710 PISVSWFHEGNEISSGRKYQTTLTDNT----CALTVNMLEESDSGDYTCIATN---MAGS 7762
Query: 128 NQGILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLEGRDIVP--- 184
++ ++V PS TG ++ + + GTP W K ++VP
Sbjct: 7763 DECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSI-VKGTPPFSVSWFK-GSSELVPGDR 7820
Query: 185 VKENFNPTTGILVIGNLTNFEQGYYQCTAINRLGNSSCEIDLTSSHP 231
+ + L + ++ + G Y C N G +SC L P
Sbjct: 7821 CNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAP 7867
Score = 34.3 bits (77), Expect = 0.20
Identities = 30/103 (29%), Positives = 45/103 (43%), Gaps = 19/103 (18%)
Query: 89 RITGSNDPGNASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPL---- 144
RIT N P +++TI + +D+G YI + N G+ ++ V+VL KP P
Sbjct: 13736 RITIENVPKKSTVTIVDSKRSDTGTYIIEAVN---VCGRATAVVEVNVLDKPGPPAAFDI 13792
Query: 145 -------CSVQGRP---ETGHTISLSCLSALGTPSPVYYWHKL 177
C + P + G I+ + T S V WHKL
Sbjct: 13793 TDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEV--WHKL 13833
Score = 33.5 bits (75), Expect = 0.33
Identities = 32/108 (29%), Positives = 46/108 (42%), Gaps = 15/108 (13%)
Query: 276 LEPMTKINPRGESEAMPREDATQLEVTLPSSIHETGPDTIQEPDYEPKPTQEPAPEPAPG 335
+EP K+ E A P E A V +P + P + P +P P +E P P P
Sbjct: 9282 VEPPPKVPELPEKPA-PEEVAP---VPIPKKVEPPAPKVPEVPK-KPVP-EEKKPVPVPK 9335
Query: 336 SEPMAVPDLDIELELEPETQSEL--------EPEPEPEPESEPGVVVE 375
EP A P + E+ +P + ++ E P PE + GVV E
Sbjct: 9336 KEPAAPPKVP-EVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTE 9382
Score = 33.5 bits (75), Expect = 0.33
Identities = 15/61 (24%), Positives = 28/61 (45%)
Query: 166 GTPSPVYYWHKLEGRDIVPVKENFNPTTGILVIGNLTNFEQGYYQCTAINRLGNSSCEID 225
G P+P W + G + + +L++GN+ F+ G Y T N G+ S ++
Sbjct: 21886 GRPAPEVKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVN 21945
Query: 226 L 226
+
Sbjct: 21946 V 21946
Score = 33.1 bits (74), Expect = 0.44
Identities = 33/111 (29%), Positives = 49/111 (44%), Gaps = 7/111 (6%)
Query: 275 ELEPMTKINPRGESEAMPREDA---TQLEVTLPSSIHETGPDTIQEPDYEPKPTQEPAPE 331
E+ P + P E E +P E+ + +V +P+ + E ++ PK +E AP
Sbjct: 10153 EVPPEEEYVPE-EEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPK--KEEAPP 10209
Query: 332 PAPGSEPMAVPDLDIELELEPETQS-ELEPEPEPEPESEPGVVVEPLSEDE 381
P V + I L E E E+ EPE EP SE + EP S +E
Sbjct: 10210 AKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEE 10260
Score = 32.7 bits (73), Expect = 0.57
Identities = 37/143 (25%), Positives = 64/143 (44%), Gaps = 20/143 (13%)
Query: 98 NASITISHMQPADSGIYICDVNNPPDFLGQN--QGILNV----SVLVKPSKPLCSVQGRP 151
+ S+ +++++ D+ Y C V+N G + GIL V S LVKP + Q P
Sbjct: 5291 SVSLEVNNLELEDTANYTCKVSN---VAGDDACSGILTVKEPPSFLVKPGRQ----QAIP 5343
Query: 152 ETGHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENF---NPTTGILVIGNLTNFEQGY 208
++ T+ + GTP W K + ++V + F +T L + ++ + G
Sbjct: 5344 DS--TVEFKAILK-GTPPFKIKWFK-DDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQ 5399
Query: 209 YQCTAINRLGNSSCEIDLTSSHP 231
Y C N +G+ SC L + P
Sbjct: 5400 YTCHVTNDVGSDSCTTMLLVTEP 5422
Score = 32.7 bits (73), Expect = 0.57
Identities = 31/155 (20%), Positives = 63/155 (40%), Gaps = 13/155 (8%)
Query: 101 ITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRP--ETGHTIS 158
+ + + + +G Y C V N + + ++ +P K + ++ + G +
Sbjct: 5387 LNLYSVDASKTGQYTCHVTNDVG----SDSCTTMLLVTEPPKFVKKLEASKIVKAGDSSR 5442
Query: 159 LSCLSALGTPSPVYYW----HKLEGRDIVPVKENFNPTTGILVIGNLTNFEQGYYQCTAI 214
L C A G+P W H+L D + F + ++ + NL+ + G + C A
Sbjct: 5443 LECKIA-GSPEIRVVWFRNEHELPASD--KYRMTFIDSVAVIQMNNLSTEDSGDFICEAQ 5499
Query: 215 NRLGNSSCEIDLTSSHPEVGIIVGALIGSLVGAAI 249
N G++SC + P V ++ +L A +
Sbjct: 5500 NPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEV 5534
Score = 32.3 bits (72), Expect = 0.74
Identities = 37/166 (22%), Positives = 57/166 (34%), Gaps = 13/166 (7%)
Query: 77 GGQAVAIGQFKDRITGSNDPGN--------ASITISHMQPADSGIYICDVNNPPDFLGQN 128
G + + + +KD + +D A++ I + G Y C +NP +
Sbjct: 7141 GSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSS 7200
Query: 129 QGILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLEGRDIVP---V 185
++ V P L V G + + C GT W K + R+I P
Sbjct: 7201 AKLILSEHEVPPFFDLKPVSVDLALGESGTFKC-HVTGTAPIKITWAK-DNREIRPGGNY 7258
Query: 186 KENFNPTTGILVIGNLTNFEQGYYQCTAINRLGNSSCEIDLTSSHP 231
K T L + + + G Y C A N G SC L P
Sbjct: 7259 KMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEP 7304
Score = 32.3 bits (72), Expect = 0.74
Identities = 32/115 (27%), Positives = 49/115 (42%), Gaps = 18/115 (15%)
Query: 271 KTIAELEPMTKINPRGESEAMPREDATQLEVTLPSSIHETG---PDTIQEPDYEPKPTQE 327
K + + P P + +P+E + +V +P P+ ++P E KP
Sbjct: 10732 KKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAV- 10790
Query: 328 PAPEPAPGSEPMAVPDLDIELELEPETQSELEPEPEPEPESEPGVVVEPLSEDEK 382
P PE A P E+ EPE E+ PE E PE E V P++E+E+
Sbjct: 10791 PVPERAESPPP--------EVYEEPE---EIAPEEEIAPEEEKPV---PVAEEEE 10831
Score = 32.3 bits (72), Expect = 0.74
Identities = 26/100 (26%), Positives = 41/100 (41%), Gaps = 7/100 (7%)
Query: 129 QGILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKEN 188
+G+ + P K L Q + G + + G P P W K G D V +
Sbjct: 18888 EGVYEAKEQLLPPKILMPEQITIKAGKKLRIEA-HVYGKPHPTCKWKK--GEDEVVTSSH 18944
Query: 189 FN----PTTGILVIGNLTNFEQGYYQCTAINRLGNSSCEI 224
++ IL+I ++T + GYY TA N G + +I
Sbjct: 18945 LAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKI 18984
Score = 32.0 bits (71), Expect = 0.97
Identities = 29/128 (22%), Positives = 56/128 (43%), Gaps = 9/128 (7%)
Query: 99 ASITISHMQPADSGIYICDVNNPPDFL--GQNQGILNVSVLVKPSKPLCSVQGRPETGHT 156
+S+ + ++ +DSG Y C V+N + N + + V+ +P ++ G
Sbjct: 4261 SSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPATFVEKLEPSQLLK----KGDA 4316
Query: 157 ISLSCLSALGTPSPVYYW--HKLEGRDIVPVKENFNPTTGILVIGNLTNFEQGYYQCTAI 214
L+C GTP W + E ++ + +F +T +L + ++ + G Y C A
Sbjct: 4317 TQLAC-KVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQ 4375
Query: 215 NRLGNSSC 222
N G+ C
Sbjct: 4376 NEAGSDHC 4383
Score = 32.0 bits (71), Expect = 0.97
Identities = 23/85 (27%), Positives = 34/85 (40%), Gaps = 1/85 (1%)
Query: 287 ESEAMPREDATQLEVTLPSSIHETGPDTIQEPDYEPKPTQEPAPEP-APGSEPMAVPDLD 345
E E Q E+ IH ++ P P+ ++PAPE AP P V
Sbjct: 9254 EEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPA 9313
Query: 346 IELELEPETQSELEPEPEPEPESEP 370
++ P+ E +P P P+ EP
Sbjct: 9314 PKVPEVPKKPVPEEKKPVPVPKKEP 9338
Score = 31.6 bits (70), Expect = 1.3
Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 9/82 (10%)
Query: 304 PSSIHETGPDTIQE---PDYEPKPTQEPAPEPAPGSEPMAVPDLDIELELEPETQSELEP 360
P+ + E I E P PK + P P+ EP+ VP + + E E + E+ P
Sbjct: 10057 PAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVP-VALPQEEEVLFEEEIVP 10115
Query: 361 EPEPEPESEPGVVVEPLSEDEK 382
E E PE E E L E+E+
Sbjct: 10116 EEEVLPEEE-----EVLPEEEE 10132
Score = 31.6 bits (70), Expect = 1.3
Identities = 31/127 (24%), Positives = 52/127 (40%), Gaps = 20/127 (15%)
Query: 260 KAKAKAKERNSKTIAELEPMTKINPRGESEAMPREDATQLEVTLPSSIHETGP----DTI 315
K + ER + E+ + + R E E P+ + +LE ++ E P + +
Sbjct: 10931 KVRKLLPERKPEPKEEVVLKSVLRKRPEEEE-PKVEPKKLEKVKKPAVPEPPPPKPVEEV 10989
Query: 316 QEPDYE------PKPTQEPAPEPA---PGSEPMAVPDLDIELELEPETQSELEPEPEPEP 366
+ P P+PT+ P +PA P EP P+ +++ P EPEP P
Sbjct: 10990 EVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPV------EPEPTP 11043
Query: 367 ESEPGVV 373
+ P V
Sbjct: 11044 IAAPVTV 11050
Score = 31.6 bits (70), Expect = 1.3
Identities = 34/136 (25%), Positives = 58/136 (42%), Gaps = 11/136 (8%)
Query: 88 DRITGSNDPGNASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSV 147
DR+T ND +A + + AD+GIY + N LG +NV V+ P P +
Sbjct: 14431 DRLTMKNDHISAHLEVPKSVRADAGIYTITLENK---LGSATASINVKVIGLPG-PCKDI 14486
Query: 148 QGRPETGHTISLSCLSAL---GTPSPVYYWHKLEG--RDIVPVKENFNPTTGILVIGNLT 202
+ T + L+ GTP Y + E R +PV N + + +L
Sbjct: 14487 KASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLS--WTVKDLI 14544
Query: 203 NFEQGYYQCTAINRLG 218
+ +++ A+N++G
Sbjct: 14545 PNGEYFFRVKAVNKVG 14560
Score = 31.2 bits (69), Expect = 1.7
Identities = 48/207 (23%), Positives = 75/207 (36%), Gaps = 29/207 (14%)
Query: 31 VNVTVGSNVTLICIYTTTVASREQLSIQWSFFHKKEMEPISIYFSQGGQAVAIGQFKDRI 90
V +G TL C V ++ I W H K + QFK+ +
Sbjct: 7029 VEAVIGEPATLQC----KVDGTPEIRISWYKEHTKLRSAPAYKM----------QFKNNV 7074
Query: 91 TGSNDPGNASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGR 150
AS+ I+ + +D G Y C +N + + +L + P ++
Sbjct: 7075 --------ASLVINKVDHSDVGEYSCKADNSVGAVASS-AVLVIKARKLPPFFARKLKDV 7125
Query: 151 PET-GHTISLSCLSALGTPSPVYYWHKLEG---RDIVPVKENFNPTTGILVIGNLTNFEQ 206
ET G ++ C P V W+K +G +D ++ +F L I
Sbjct: 7126 HETLGFPVAFECRINGSEPLQVS-WYK-DGVLLKDDANLQTSFVHNVATLQILQTDQSHI 7183
Query: 207 GYYQCTAINRLGNSSCEIDLTSSHPEV 233
G Y C+A N LG +S L S EV
Sbjct: 7184 GQYNCSASNPLGTASSSAKLILSEHEV 7210
Score = 30.8 bits (68), Expect = 2.2
Identities = 35/143 (24%), Positives = 55/143 (38%), Gaps = 18/143 (12%)
Query: 97 GNASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPETG-- 154
G A+ IS + +SG Y+C+ N + G + S+ +K +P ++
Sbjct: 4915 GLATFQISGARVENSGTYVCEARN-------DAGTASCSIELKVKEPPTFIRELKPVEVV 4967
Query: 155 --HTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTTGILV----IGNLTNFEQGY 208
+ L C GTP W K R+I K+ + T + V I + G
Sbjct: 4968 KYSDVELEC-EVTGTPPFEVTWLK-NNREIRSSKK-YTLTDRVSVFNLHITKCDPSDTGE 5024
Query: 209 YQCTAINRLGNSSCEIDLTSSHP 231
YQC N G+ SC + P
Sbjct: 5025 YQCIVSNEGGSCSCSTRVALKEP 5047
Score = 30.8 bits (68), Expect = 2.2
Identities = 36/165 (21%), Positives = 63/165 (38%), Gaps = 20/165 (12%)
Query: 76 QGGQAVAIGQFKDRITGSNDPGNASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVS 135
+ GQ + G + T +D G +TI+ + D Y N G++ ++
Sbjct: 31725 KSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDDDAEYTVVARNK---YGEDSCKAKLT 31781
Query: 136 VLVKPS------KPLCS---VQGRPETGHTISLSCLSALGTPSPVYYWHK-----LEGRD 181
V + P +P+ + G ++ + G P P W K G +
Sbjct: 31782 VTLHPPPTDSTLRPMFKRLLANAECQEGQSVCFE-IRVSGIPPPTLKWEKDGQPLSLGPN 31840
Query: 182 IVPVKENFNPTTGILVIGNLTNFEQGYYQCTAINRLGNSSCEIDL 226
I + E + L I + + GYY+ TA N G++SC+ L
Sbjct: 31841 IEIIHEGLDYYA--LHIRDTLPEDTGYYRVTATNTAGSTSCQAHL 31883
Score = 30.4 bits (67), Expect = 2.8
Identities = 31/136 (22%), Positives = 54/136 (39%), Gaps = 3/136 (2%)
Query: 99 ASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPET-GHTI 157
A++ + + DSG Y C N ++ + + P ++ +T G +
Sbjct: 6134 ATLVFNKVNINDSGEYTCKAENSIG-TASSKTVFRIQERQLPPSFARQLKDIEQTVGLPV 6192
Query: 158 SLSCLSALGTPSPV-YYWHKLEGRDIVPVKENFNPTTGILVIGNLTNFEQGYYQCTAINR 216
+L+C P V +Y + RD ++ +F L I G Y C+A N
Sbjct: 6193 TLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNP 6252
Query: 217 LGNSSCEIDLTSSHPE 232
LG +S LT+ P+
Sbjct: 6253 LGTASSSARLTAREPK 6268
Score = 30.4 bits (67), Expect = 2.8
Identities = 30/117 (25%), Positives = 47/117 (40%), Gaps = 19/117 (16%)
Query: 277 EPMTKINPRGESEAMPREDATQLEVTLPSSIHETGPDTIQEPDYEPKPTQEPAPEPAPGS 336
E ++ P + A P + V +P + E P+ + P PK + P P P
Sbjct: 10583 EAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEK-KVPVPPPKKPEVP-PTKVPEV 10640
Query: 337 EPMAVPDLDIELELEPETQS---ELEPEPE--------------PEPESEPGVVVEP 376
+AVP+ + + P+ +S E+ EPE PEP + P V V P
Sbjct: 10641 PKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPP 10697
Score = 30.0 bits (66), Expect = 3.7
Identities = 44/199 (22%), Positives = 78/199 (39%), Gaps = 25/199 (12%)
Query: 166 GTPSPVYYWHKLEGRDIVPVKENFN--PTTGILVIGNLTNFEQGYYQCTAINRLGNSSCE 223
G P+P W K+ G D V K + T LVI N T + G Y T +N G +
Sbjct: 18632 GRPAPKVTWRKV-GIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVF 18690
Query: 224 IDLTSSHPEVGIIVGALIGSLVGAAIIISVVCFARNKAK------AKAKERNSKTIAELE 277
+++ G + + + + +S + + +E + KT + +
Sbjct: 18691 VNVRVLDTP-GPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVT 18749
Query: 278 PMTKINPRGESEAMPREDATQLEVTLPSSIHETGPDTIQEPDYEPKPTQEPAPEPAPGSE 337
P K + +P + VT +++E GP PT P+P S+
Sbjct: 18750 PEVKKTSFHVTNLVPGNE-YYFRVT---AVNEYGPGV---------PTD--VPKPVLASD 18794
Query: 338 PMAVPDLDIELELEPETQS 356
P++ PD +LE+ T++
Sbjct: 18795 PLSEPDPPRKLEVTEMTKN 18813
Score = 30.0 bits (66), Expect = 3.7
Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 3/72 (4%)
Query: 89 RITGSNDPGNASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQ 148
R+ + N+ +TI D G Y+ + N G+ LNV VL KP P V+
Sbjct: 22193 RVNAESTENNSLLTIKDACREDVGHYVVKLTNSA---GEAIETLNVIVLDKPGPPTGPVK 22249
Query: 149 GRPETGHTISLS 160
T +I+LS
Sbjct: 22250 MDEVTADSITLS 22261
Score = 29.6 bits (65), Expect = 4.8
Identities = 34/165 (20%), Positives = 63/165 (38%), Gaps = 14/165 (8%)
Query: 68 EPISIYFSQGGQAVAIGQFKDRITGSNDPGNASITISHMQPADSGIYICDVNNPPDFLGQ 127
EPIS+ + + G+ + + + S A++ I + +G Y C NP +G
Sbjct: 8084 EPISVSWYKDGKPL---KDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNP---IGS 8137
Query: 128 NQGILNVSVLVKPSKPLCSVQGRPE---TGHTISLSCLSALGTPSPVYYWHKLEGRDIVP 184
+ + + P ++ P G + C GT W K + R+I
Sbjct: 8138 ASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFEC-HVTGTQPIKVSWAK-DSREIRS 8195
Query: 185 ---VKENFNPTTGILVIGNLTNFEQGYYQCTAINRLGNSSCEIDL 226
+ ++ + L + + + G Y C A+N +G SC L
Sbjct: 8196 GGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQL 8240
Score = 29.6 bits (65), Expect = 4.8
Identities = 34/134 (25%), Positives = 50/134 (37%), Gaps = 14/134 (10%)
Query: 264 KAKERNSKTIAELEPMTKINPRGES---EAMPREDATQLEVTLPSSIHETGPDTIQEPDY 320
K E + E + I P+ ES E + LE + E P P
Sbjct: 10636 KVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAA---PPQ 10692
Query: 321 EPKPTQEPAPE---PA-----PGSEPMAVPDLDIELELEPETQSELEPEPEPEPESEPGV 372
P ++P PE PA P P+ VP++ E+ E + + +PE P P V
Sbjct: 10693 VTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEV 10752
Query: 373 VVEPLSEDEKGVVK 386
E + E + V K
Sbjct: 10753 PKEVVPEKKVAVPK 10766
Score = 29.3 bits (64), Expect = 6.3
Identities = 34/139 (24%), Positives = 53/139 (38%), Gaps = 16/139 (11%)
Query: 100 SITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPETGHTISL 159
++ I+ P+D+G Y C V+N G + S V +P ++ T +
Sbjct: 5011 NLHITKCDPSDTGEYQCIVSN-------EGGSCSCSTRVALKEPPSFIKKIENTTTVLKS 5063
Query: 160 SCL---SALGTPSPVYYWHK----LEGRDIVPVKENFNPTTGILVIGNLTNFEQGYYQCT 212
S + G+P W K L+ D V + +F + L I ++ N G Y C
Sbjct: 5064 SATFQSTVAGSPPISITWLKDDQILDEDDNVYI--SFVDSVATLQIRSVDNGHSGRYTCQ 5121
Query: 213 AINRLGNSSCEIDLTSSHP 231
A N G C L P
Sbjct: 5122 AKNESGVERCYAFLLVQEP 5140
Score = 29.3 bits (64), Expect = 6.3
Identities = 34/126 (26%), Positives = 53/126 (42%), Gaps = 11/126 (8%)
Query: 263 AKAKERNSKTIAELEPMTKINPRGESEAMPREDATQLEVTLPSSIHETGPDTIQE---PD 319
AK E K I E + T + P+ P+ + V +P ++ + +E P+
Sbjct: 10058 AKVPEVPKKLIPEEKKPTPV-PKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPE 10116
Query: 320 YEPKPTQE---PAPEPAPGSEPMAVPDLDIELELEPETQSELEPEPEPEPESEPGVVVEP 376
E P +E P E E +P+ E E+ PE + E+ PE E PE E V E
Sbjct: 10117 EEVLPEEEEVLPEEEEVLPEEEEVLPE---EEEIPPE-EEEVPPEEEYVPEEEEFVPEEE 10172
Query: 377 LSEDEK 382
+ + K
Sbjct: 10173 VLPEVK 10178
Score = 28.9 bits (63), Expect = 8.2
Identities = 29/112 (25%), Positives = 45/112 (40%), Gaps = 14/112 (12%)
Query: 260 KAKAKAKERNSKTIAELEPMTKINPRGESEAMPREDATQLEVTLPSSIHETGPDTIQEPD 319
K + K E+ K P K P E E +P + ++ P+ + E P I P
Sbjct: 10963 KVEPKKLEKVKKPAVPEPPPPK--PVEEVE-VPTVTKRERKIPEPTKVPEIKP-AIPLPA 11018
Query: 320 YEPKPTQEPA----------PEPAPGSEPMAVPDLDIELELEPETQSELEPE 361
EPKP E PEP P + P+ VP + + E + + +P+
Sbjct: 11019 PEPKPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPK 11070
>gi|67188443 CD276 antigen isoform a [Homo sapiens]
Length = 534
Score = 53.5 bits (127), Expect = 3e-07
Identities = 56/219 (25%), Positives = 93/219 (42%), Gaps = 32/219 (14%)
Query: 14 CLAGQVSVVQVTIPDGFVNVTVGSNVTLICIYTTTVA-SREQLSIQWSFFHKKEMEPISI 72
CL G ++V +P+ V VG++ TL C ++ S QL++ W K++
Sbjct: 24 CLTG---ALEVQVPEDPVVALVGTDATLCCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFA 80
Query: 73 YFSQGGQAVA--IGQFKDRITGSNDPGNASITISHMQPADSGIYICDVNNPPDFLGQNQG 130
G A A F D + GNAS+ + ++ AD G + C V + DF
Sbjct: 81 EGQDQGSAYANRTALFPDLLA----QGNASLRLQRVRVADEGSFTCFV-SIRDF---GSA 132
Query: 131 ILNVSVLVKPSKPLCSVQGRPE--TGHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKEN 188
+++ V SKP +++ + G T++++C S G P +W +G
Sbjct: 133 AVSLQVAAPYSKPSMTLEPNKDLRPGDTVTITCSSYQGYPEAEVFWQDGQG--------- 183
Query: 189 FNPTTGILVIGNLTNFEQGYYQCTAINRL-----GNSSC 222
P TG + + N EQG + +I R+ G SC
Sbjct: 184 -VPLTGNVTTSQMAN-EQGLFDVHSILRVVLGANGTYSC 220
Score = 52.0 bits (123), Expect = 9e-07
Identities = 64/276 (23%), Positives = 111/276 (40%), Gaps = 48/276 (17%)
Query: 22 VQVTIPDGFVNVTVGSNVTLICIYTTTVA-SREQLSIQWSFFHKKEMEPISIYFSQGGQA 80
V+V +P+ V VG++ TL C ++ S QL++ W K++ G A
Sbjct: 247 VEVQVPEDPVVALVGTDATLRCSFSPEPGFSLAQLNLIWQLTDTKQLVHSFTEGRDQGSA 306
Query: 81 VA--IGQFKDRITGSNDPGNASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLV 138
A F D + GNAS+ + ++ AD G + C V + DF +++ V
Sbjct: 307 YANRTALFPDLLA----QGNASLRLQRVRVADEGSFTCFV-SIRDF---GSAAVSLQVAA 358
Query: 139 KPSKPLCSVQGRPE--TGHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTTGIL 196
SKP +++ + G T++++C S G P +W +G P TG +
Sbjct: 359 PYSKPSMTLEPNKDLRPGDTVTITCSSYRGYPEAEVFWQDGQG----------VPLTGNV 408
Query: 197 VIGNLTNFEQGYYQCTAINRL-----GNSSC-------------EIDLTSS----HPEVG 234
+ N EQG + ++ R+ G SC + +T PE
Sbjct: 409 TTSQMAN-EQGLFDVHSVLRVVLGANGTYSCLVRNPVLQQDAHGSVTITGQPMTFPPEAL 467
Query: 235 IIVGALIGSLVGAAIIISVVCFARNKAKAKAKERNS 270
+ L L+ + ++ VC+ K K +E N+
Sbjct: 468 WVTVGLSVCLIALLVALAFVCW--RKIKQSCEEENA 501
>gi|28373126 contactin 4 isoform c precursor [Homo sapiens]
Length = 698
Score = 53.5 bits (127), Expect = 3e-07
Identities = 46/166 (27%), Positives = 76/166 (45%), Gaps = 8/166 (4%)
Query: 87 KDRITGSNDPGNASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCS 146
+DRI + G +ITI ++ +D+G+Y C N + N + ++V S+ L
Sbjct: 31 RDRI--QIEQGTLNITIVNL--SDAGMYQCLAENKHGVIFSNAELSVIAVGPDFSRTLLK 86
Query: 147 VQGRPETGHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTT-GILVIGNLTNFE 205
+ G + + C +P PVY W K GRDI+ E + G L I N+T +
Sbjct: 87 RVTLVKVGGEVVIEC-KPKASPKPVYTWKK--GRDILKENERITISEDGNLRIINVTKSD 143
Query: 206 QGYYQCTAINRLGNSSCEIDLTSSHPEVGIIVGALIGSLVGAAIII 251
G Y C A N G +S +L P ++ + + VG +I++
Sbjct: 144 AGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSSMDVTVGESIVL 189
>gi|28373122 contactin 4 isoform a precursor [Homo sapiens]
Length = 1026
Score = 53.5 bits (127), Expect = 3e-07
Identities = 46/166 (27%), Positives = 76/166 (45%), Gaps = 8/166 (4%)
Query: 87 KDRITGSNDPGNASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCS 146
+DRI + G +ITI ++ +D+G+Y C N + N + ++V S+ L
Sbjct: 359 RDRI--QIEQGTLNITIVNL--SDAGMYQCLAENKHGVIFSNAELSVIAVGPDFSRTLLK 414
Query: 147 VQGRPETGHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTT-GILVIGNLTNFE 205
+ G + + C +P PVY W K GRDI+ E + G L I N+T +
Sbjct: 415 RVTLVKVGGEVVIEC-KPKASPKPVYTWKK--GRDILKENERITISEDGNLRIINVTKSD 471
Query: 206 QGYYQCTAINRLGNSSCEIDLTSSHPEVGIIVGALIGSLVGAAIII 251
G Y C A N G +S +L P ++ + + VG +I++
Sbjct: 472 AGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSSMDVTVGESIVL 517
Score = 52.4 bits (124), Expect = 7e-07
Identities = 45/150 (30%), Positives = 65/150 (43%), Gaps = 26/150 (17%)
Query: 93 SNDPGNASITISHMQPADSGIYICDVNN----------PPDFLGQNQGILNVSVLVKPSK 142
S + GN + I+ ++ +D G Y C V N P + +N G++ +
Sbjct: 173 SQETGN--LYIAKVEKSDVGNYTCVVTNTVTNHKVLGPPTPLILRNDGVMG------EYE 224
Query: 143 PLCSVQGRPET-----GHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTTGILV 197
P VQ PET G T+ L C ALG P P W + +G+ I K + + GIL
Sbjct: 225 PKIEVQF-PETVPTAKGATVKLECF-ALGNPVPTIIWRRADGKPIAR-KARRHKSNGILE 281
Query: 198 IGNLTNFEQGYYQCTAINRLGNSSCEIDLT 227
I N + G Y+C A N G + LT
Sbjct: 282 IPNFQQEDAGLYECVAENSRGKNVARGQLT 311
Score = 32.0 bits (71), Expect = 0.97
Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 4/64 (6%)
Query: 157 ISLSCLSALGTPSPVYYWHKLEGRDI-VPVKENFNPTTGILVIGNLTNFEQ-GYYQCTAI 214
+ L+C G P P W KL G D+ + ++ G L+I N + G YQCTA
Sbjct: 46 VKLNC-EVKGNPKPHIRW-KLNGTDVDTGMDFRYSVVEGSLLINNPNKTQDAGTYQCTAT 103
Query: 215 NRLG 218
N G
Sbjct: 104 NSFG 107
>gi|54607118 leucine-rich repeats and immunoglobulin-like domains 1
[Homo sapiens]
Length = 1093
Score = 53.5 bits (127), Expect = 3e-07
Identities = 43/200 (21%), Positives = 83/200 (41%), Gaps = 13/200 (6%)
Query: 96 PGNASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPETGH 155
P + I+ ++ D+G+Y C N + N ++VL PS + G
Sbjct: 652 PDDDVFFITDVKIDDAGVYSCTAQNSAGSISANA---TLTVLETPSLVVPLEDRVVSVGE 708
Query: 156 TISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTTGILVIGNLTNFEQGYYQCTAIN 215
T++L C A G P P W K + + + + P +LV+ N+ + G Y C N
Sbjct: 709 TVALQC-KATGNPPPRITWFKGDRPLSLTERHHLTPDNQLLVVQNVVAEDAGRYTCEMSN 767
Query: 216 RLGNSSCEIDLT--------SSHPEVGIIVGALIGSLVGAAII-ISVVCFARNKAKAKAK 266
LG L+ VGI A++ S+V +++ + ++ R K++ +
Sbjct: 768 TLGTERAHSQLSVLPAAGCRKDGTTVGIFTIAVVSSIVLTSLVWVCIIYQTRKKSEEYSV 827
Query: 267 ERNSKTIAELEPMTKINPRG 286
+T+ + + ++ +G
Sbjct: 828 TNTDETVVPPDVPSYLSSQG 847
Score = 38.9 bits (89), Expect = 0.008
Identities = 37/132 (28%), Positives = 54/132 (40%), Gaps = 9/132 (6%)
Query: 102 TISHMQPAD---SGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPETGHTIS 158
TI H++ G Y C + N ++ L V+VL +K + R T
Sbjct: 560 TILHLRQVTFGHEGRYQCVITNHFGSTYSHKARLTVNVLPSFTKTPHDITIRTTT--MAR 617
Query: 159 LSCLSALGTPSPVYYWHKLEGRDIVPVKE---NFNPTTGILVIGNLTNFEQGYYQCTAIN 215
L C +A G P+P W K G D +E + P + I ++ + G Y CTA N
Sbjct: 618 LEC-AATGHPNPQIAWQKDGGTDFPAARERRMHVMPDDDVFFITDVKIDDAGVYSCTAQN 676
Query: 216 RLGNSSCEIDLT 227
G+ S LT
Sbjct: 677 SAGSISANATLT 688
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 53.1 bits (126), Expect = 4e-07
Identities = 37/134 (27%), Positives = 57/134 (42%), Gaps = 4/134 (2%)
Query: 98 NASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPETGHTI 157
+ S+ I+ + +DSG+Y+C N G + ++V V P + + G +
Sbjct: 1132 SGSMKITETRTSDSGMYLCVATN---IAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRV 1188
Query: 158 SLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTTGILVIGNLTNFEQGYYQCTAINRL 217
+ C +A GTP PV W K +V + + + G L I T + G Y C A N
Sbjct: 1189 DIPC-NAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIA 1247
Query: 218 GNSSCEIDLTSSHP 231
G EI L P
Sbjct: 1248 GTDETEITLHVQEP 1261
Score = 48.1 bits (113), Expect = 1e-05
Identities = 42/134 (31%), Positives = 58/134 (43%), Gaps = 5/134 (3%)
Query: 98 NASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPETGHTI 157
+ + IS D+G Y+C NP G G + ++V V P + I
Sbjct: 4040 SGGLQISRAVREDAGTYMCVAQNPA---GTALGKIKLNVQVPPVISPHLKEYVIAVDKPI 4096
Query: 158 SLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTTGILVIGNLTNFEQGYYQCTAINRL 217
+LSC A G P P WHK +GR IV ++G L I + + G+Y C A N
Sbjct: 4097 TLSC-EADGLPPPDITWHK-DGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVA 4154
Query: 218 GNSSCEIDLTSSHP 231
G+SS LT P
Sbjct: 4155 GSSSTSTKLTVHVP 4168
Score = 43.5 bits (101), Expect = 3e-04
Identities = 44/189 (23%), Positives = 80/189 (42%), Gaps = 17/189 (8%)
Query: 83 IGQFKDRITGSNDPGNASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVS---VLVK 139
+G + R+T + ++ I + P D+GIY C +N QN + + ++V
Sbjct: 653 VGSHRYRMTS-----DGTLFIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVV 707
Query: 140 PSKPLCSVQGRPETGHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTTGILVIG 199
S+ L ++ G + C ++ G P P W K + +P G+L I
Sbjct: 708 QSELLVAL------GDITVMECKTS-GIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQ 760
Query: 200 NLTNFEQGYYQCTAINRLGNSSCEIDLTSSHPEVGIIVGALIGSLVGAAIIISVVCFARN 259
+ + G Y C AIN G ++ +I L P V I A + +G+ +++ C+ +
Sbjct: 761 ETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSMEIGSN--VTLPCYVQG 818
Query: 260 KAKAKAKER 268
+ K R
Sbjct: 819 YPEPTIKWR 827
Score = 43.5 bits (101), Expect = 3e-04
Identities = 37/146 (25%), Positives = 63/146 (43%), Gaps = 18/146 (12%)
Query: 98 NASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPS-----KPLCSVQGRPE 152
+ +++I P+D+GIY C N G ++ + + V P+ P +
Sbjct: 1223 DGTLSIDQATPSDAGIYTCVATN---IAGTDETEITLHVQEPPTVEDLEPPYNTTFQERV 1279
Query: 153 TGHTISLSCLSALGTPSPVYYW----HKLEGRDI-VPVKENFNPTTGILVIGNLTNFEQG 207
I C A GTP P W +L GR+ + + E+ +LVI ++T ++ G
Sbjct: 1280 ANQRIEFPC-PAKGTPKPTIKWLHNGRELTGREPGISILEDGT----LLVIASVTPYDNG 1334
Query: 208 YYQCTAINRLGNSSCEIDLTSSHPEV 233
Y C A+N G + + +L P V
Sbjct: 1335 EYICVAVNEAGTTERKYNLKVHVPPV 1360
Score = 43.5 bits (101), Expect = 3e-04
Identities = 41/148 (27%), Positives = 60/148 (40%), Gaps = 15/148 (10%)
Query: 108 PADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPET--GHTISLSCLSAL 165
P D+G Y C N G +Q N+ VLV P+ + ++L C
Sbjct: 1423 PEDAGRYSCKAIN---IAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALEC-QVK 1478
Query: 166 GTPSPVYYWHKLEGRDIVPVKENFN--PTTGILVIGNLTNFEQGYYQCTAINRLGNSSCE 223
GTP P +W K +G+ + N +L + N ++G YQCT N G + +
Sbjct: 1479 GTPFPDIHWFK-DGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKD 1537
Query: 224 IDLTSSHP------EVGIIVGALIGSLV 245
I LT P V + LI SL+
Sbjct: 1538 IKLTIYIPPSIKGGNVTTDISVLINSLI 1565
Score = 42.4 bits (98), Expect = 7e-04
Identities = 40/136 (29%), Positives = 59/136 (43%), Gaps = 16/136 (11%)
Query: 98 NASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPS-----KPLCSVQGRPE 152
+ S+ I +Q D G Y C +N G N +V V V P+ + L +++G P
Sbjct: 942 DGSLHIERVQLQDGGEYTCVASN---VAGTNNKTTSVVVHVLPTIQHGQQILSTIEGIP- 997
Query: 153 TGHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNP-TTGILVIGNLTNFEQGYYQC 211
++L C A G P P W K +G I F+ G L + + E G Y C
Sbjct: 998 ----VTLPC-KASGNPKPSVIWSK-KGELISTSSAKFSAGADGSLYVVSPGGEESGEYVC 1051
Query: 212 TAINRLGNSSCEIDLT 227
TA N G + ++ LT
Sbjct: 1052 TATNTAGYAKRKVQLT 1067
Score = 41.6 bits (96), Expect = 0.001
Identities = 45/161 (27%), Positives = 60/161 (37%), Gaps = 13/161 (8%)
Query: 95 DPGNASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPETG 154
DP + I Q D+G Y C N G+ G + + V P E G
Sbjct: 751 DPLLGLLKIQETQDLDAGDYTCVAINEA---GRATGKITLDVGSPPVFIQEPADVSMEIG 807
Query: 155 HTISLSCLSALGTPSPVYYWHKLEGRDIVP----VKENFNPTTGILVIGNLTNFEQGYYQ 210
++L C G P P W +L+ I V TG L I NL ++G Y
Sbjct: 808 SNVTLPCY-VQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYI 866
Query: 211 CTAINRLGNSSCEIDLTSSHPEVGIIVGALIGSLVGAAIII 251
C A N+ G E +T V +V LIG A +I
Sbjct: 867 CEAENQFGKIQSETTVT-----VTGLVAPLIGISPSVANVI 902
Score = 41.2 bits (95), Expect = 0.002
Identities = 48/195 (24%), Positives = 80/195 (41%), Gaps = 30/195 (15%)
Query: 31 VNVTVGSNVTLICIYTTTVASREQLSIQWSFFHKKEMEPISIYFSQGGQAVAIGQFKDRI 90
V++ +GSNVTL C V + +I+W + + PI FS+ +I Q +
Sbjct: 802 VSMEIGSNVTLPCY----VQGYPEPTIKW---RRLDNMPI---FSRPFSVSSISQLR--- 848
Query: 91 TGSNDPGNASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGR 150
++ I ++ +D G YIC+ N + Q++ + V+ LV P +
Sbjct: 849 -------TGALFILNLWASDKGTYICEAENQFGKI-QSETTVTVTGLVAPLIGISPSVAN 900
Query: 151 PETGHTISLSCLSALGTPSPVYYWHK----LEGRDIVPVKENFNPTTGILVIGNLTNFEQ 206
G ++L C G P P W K L + V+ + G L I + +
Sbjct: 901 VIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSD-----GSLHIERVQLQDG 955
Query: 207 GYYQCTAINRLGNSS 221
G Y C A N G ++
Sbjct: 956 GEYTCVASNVAGTNN 970
Score = 41.2 bits (95), Expect = 0.002
Identities = 43/167 (25%), Positives = 70/167 (41%), Gaps = 22/167 (13%)
Query: 67 MEPISIYFSQGGQAVAIGQFKDRITGSNDPGNASITISHMQPADSGIYICDVNNPPDFLG 126
+ P I + + G+A+ + + R+ S S+ I+ +QP D+G Y C N G
Sbjct: 4105 LPPPDITWHKDGRAI-VESIRQRVLSSG-----SLQIAFVQPGDAGHYTCMAAN---VAG 4155
Query: 127 QNQGILNVSVLVKPSKPLCSVQGRPETGHTIS--LSCLSALGTPSPVYYWHKLEGRDIVP 184
+ ++V V P + S +G L C+ A G P+P W K D V
Sbjct: 4156 SSSTSTKLTVHVPPR--IRSTEGHYTVNENSQAILPCV-ADGIPTPAINWKK----DNVL 4208
Query: 185 VKENFNPTT----GILVIGNLTNFEQGYYQCTAINRLGNSSCEIDLT 227
+ T G L++ N+ + G+Y C A N G + + LT
Sbjct: 4209 LANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLT 4255
Score = 40.4 bits (93), Expect = 0.003
Identities = 39/142 (27%), Positives = 61/142 (42%), Gaps = 15/142 (10%)
Query: 97 GNASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKP------SKPLCSVQGR 150
G + IS + +D+ +Y C +N G + N+ V ++P S P + R
Sbjct: 2250 GGRQLQISIAEKSDAALYSCVASN---VAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTR 2306
Query: 151 PETGHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTTG-ILVIGNLTNFEQGYY 209
G +ISL C G P P W K +G ++ K G IL + N+ + G Y
Sbjct: 2307 ---GKSISLEC-EVQGIPPPTVTWMK-DGHPLIKAKGVEILDEGHILQLKNIHVSDTGRY 2361
Query: 210 QCTAINRLGNSSCEIDLTSSHP 231
C A+N G + + DL+ P
Sbjct: 2362 VCVAVNVAGMTDKKYDLSVHAP 2383
Score = 40.4 bits (93), Expect = 0.003
Identities = 37/129 (28%), Positives = 60/129 (46%), Gaps = 14/129 (10%)
Query: 97 GNASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPET--G 154
G + + I+ Q +DSG Y C +N G+ Q +S+ V PS + G
Sbjct: 3205 GGSKLQIARSQHSDSGNYTCIASN---MEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLG 3261
Query: 155 HTISLSCLSALGTPSPVYYWHKLEGRDIVP-----VKENFNPTTGILVIGNLTNFEQGYY 209
+ L C +A G P+P+ W K +G+ I ++ + N +T + + G LT+ + G Y
Sbjct: 3262 ENVELVC-NANGIPTPLIQWLK-DGKPIASGETERIRVSANGST-LNIYGALTS-DTGKY 3317
Query: 210 QCTAINRLG 218
C A N G
Sbjct: 3318 TCVATNPAG 3326
Score = 40.4 bits (93), Expect = 0.003
Identities = 38/139 (27%), Positives = 58/139 (41%), Gaps = 8/139 (5%)
Query: 97 GNASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVS--VLVKPSKPLCSVQGRPETG 154
G++ + I + DSG Y+C N F+ + G + V + K P ++ P G
Sbjct: 4309 GHSELVIERVSKEDSGTYVCTAENSVGFV-KAIGFVYVKEPPVFKGDYPSNWIE--PLGG 4365
Query: 155 HTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTTGILVIGNLTNFEQGYYQCTAI 214
+ I L+C G P+P W++ +G DI G L I N + G Y C A
Sbjct: 4366 NAI-LNC-EVKGDPTPTIQWNR-KGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVAT 4422
Query: 215 NRLGNSSCEIDLTSSHPEV 233
N G + LT P +
Sbjct: 4423 NEAGVVERSMSLTLQSPPI 4441
Score = 40.0 bits (92), Expect = 0.004
Identities = 40/139 (28%), Positives = 54/139 (38%), Gaps = 40/139 (28%)
Query: 101 ITISHMQPADSGIYICDVNNP--------------PDFLGQNQGILNVSVLVKPSKPL-C 145
+ I+ + P D+G YIC N P + + + NVSVL+ L C
Sbjct: 1323 LVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFC 1382
Query: 146 SVQGRPETGHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTT----GILVIGNL 201
V+G TPSP+ W+K D V V E+ T IL +
Sbjct: 1383 EVEG-----------------TPSPIIMWYK----DNVQVTESSTIQTVNNGKILKLFRA 1421
Query: 202 TNFEQGYYQCTAINRLGNS 220
T + G Y C AIN G S
Sbjct: 1422 TPEDAGRYSCKAINIAGTS 1440
Score = 39.7 bits (91), Expect = 0.005
Identities = 38/146 (26%), Positives = 57/146 (39%), Gaps = 20/146 (13%)
Query: 95 DPGNASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPETG 154
+ G + I Q D G YIC + G+ + V VLV P+ ++G ET
Sbjct: 1691 EAGGKKLEIMSAQEIDRGQYICVATS---VAGEKEIKYEVDVLVPPA-----IEGGDETS 1742
Query: 155 HTI-------SLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTTG--ILVIGNLTNFE 205
+ I L C G+P P W L+ ++ ++ F LVI
Sbjct: 1743 YFIVMVNNLLELDC-HVTGSPPPTIMW--LKDGQLIDERDGFKILLNGRKLVIAQAQVSN 1799
Query: 206 QGYYQCTAINRLGNSSCEIDLTSSHP 231
G Y+C A N G+ E ++T P
Sbjct: 1800 TGLYRCMAANTAGDHKKEFEVTVHVP 1825
Score = 39.7 bits (91), Expect = 0.005
Identities = 35/128 (27%), Positives = 52/128 (40%), Gaps = 7/128 (5%)
Query: 101 ITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPETGHTISLS 160
I I Q +D+GIY C N G + ++ V V PS + + + L
Sbjct: 1976 IDIESAQISDAGIYKCVAINSA---GATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLE 2032
Query: 161 CLSALGTPSPVYYWHKLEGRDIVPVKENFNPTTG--ILVIGNLTNFEQGYYQCTAINRLG 218
C A G P+P W K +G + +G IL + + + G Y C A+N G
Sbjct: 2033 C-EARGIPAPSLTWLK-DGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAG 2090
Query: 219 NSSCEIDL 226
+IDL
Sbjct: 2091 EKQRDIDL 2098
Score = 38.5 bits (88), Expect = 0.010
Identities = 36/138 (26%), Positives = 57/138 (41%), Gaps = 10/138 (7%)
Query: 98 NASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPETGHTI 157
N + I D+G Y+C N G ++ +++ V V PS
Sbjct: 3765 NGFLHIQSAHVTDTGRYLCMATNAA---GTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQT 3821
Query: 158 SLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNP----TTGILVIGNLTNFEQGYYQCTA 213
+L+C A G P P W K ++ V +N N ++G LVI + + + Y+CT
Sbjct: 3822 TLAC-EATGIPKPSINWRK--NGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTV 3878
Query: 214 INRLGNSSCEIDLTSSHP 231
N G+ +DLT P
Sbjct: 3879 TNGAGDDKRTVDLTVQVP 3896
Score = 37.7 bits (86), Expect = 0.018
Identities = 37/147 (25%), Positives = 60/147 (40%), Gaps = 18/147 (12%)
Query: 100 SITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPS-KPLCSVQGRPETGHT-- 156
++ I Q +D+G Y C +N G+++ +V++ V PS + L + +TG
Sbjct: 2729 TLQIKEAQISDTGRYTCVASN---IAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGE 2785
Query: 157 ---------ISLSCLSALGTPSPVYYWHKLEGRDIVPV-KENFNPTTGILVIGNLTNFEQ 206
ISL C P P W+K +G + K P +L I +
Sbjct: 2786 AKDVIINNPISLYC-ETNAAPPPTLTWYK-DGHPLTSSDKVLILPGGRVLQIPRAKVEDA 2843
Query: 207 GYYQCTAINRLGNSSCEIDLTSSHPEV 233
G Y C A+N G S + D+ P +
Sbjct: 2844 GRYTCVAVNEAGEDSLQYDVRVLVPPI 2870
Score = 36.6 bits (83), Expect = 0.039
Identities = 43/137 (31%), Positives = 54/137 (39%), Gaps = 23/137 (16%)
Query: 101 ITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPETGHT---- 156
+ I + Q D G Y+C N G + N++V V PS V G T
Sbjct: 2928 LQILNTQITDIGRYVCVAENTA---GSAKKYFNLNVHVPPS-----VIGPKSENLTVVVN 2979
Query: 157 --ISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFN----PTTGILVIGNLTNFEQGYYQ 210
ISL+C G P P W K E P+K N N P L I + G Y
Sbjct: 2980 NFISLTC-EVSGFPPPDLSWLKNEQ----PIKLNTNTLIVPGGRTLQIIRAKVSDGGEYT 3034
Query: 211 CTAINRLGNSSCEIDLT 227
C AIN+ G S + LT
Sbjct: 3035 CIAINQAGESKKKFSLT 3051
Score = 33.9 bits (76), Expect = 0.26
Identities = 42/191 (21%), Positives = 79/191 (41%), Gaps = 10/191 (5%)
Query: 101 ITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVLVKPSKPLCSVQGRPETGHT-ISL 159
+ I+ Q +++G+Y C N G ++ V+V V P+ + R + ++L
Sbjct: 1790 LVIAQAQVSNTGLYRCMAANTA---GDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVAL 1846
Query: 160 SCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTTG--ILVIGNLTNFEQGYYQCTAINRL 217
C+ A G P+P W K + + + + N + +L I + G Y C A N
Sbjct: 1847 QCI-ANGIPNPSITWLK-DDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAA 1904
Query: 218 GNSSCEIDLTSSHPEVGIIVGALIGSLVGAAIIISVVC-FARNKAKAKAKERNSKTIAEL 276
G + I L P G ++ V + + + C A N ++++ ++
Sbjct: 1905 GETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGS 1964
Query: 277 EPMTKINPRGE 287
MT +N RG+
Sbjct: 1965 TSMTFLN-RGQ 1974
Score = 32.3 bits (72), Expect = 0.74
Identities = 30/93 (32%), Positives = 38/93 (40%), Gaps = 8/93 (8%)
Query: 147 VQGRPETGHTIS-----LSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPT-TGILVIGN 200
+Q +P H I L C A GTPSP W K EG ++ N +G L I
Sbjct: 3990 IQPQPSELHVILNNPILLPC-EATGTPSPFITWQK-EGINVNTSGRNHAVLPSGGLQISR 4047
Query: 201 LTNFEQGYYQCTAINRLGNSSCEIDLTSSHPEV 233
+ G Y C A N G + +I L P V
Sbjct: 4048 AVREDAGTYMCVAQNPAGTALGKIKLNVQVPPV 4080
Score = 30.0 bits (66), Expect = 3.7
Identities = 33/139 (23%), Positives = 54/139 (38%), Gaps = 43/139 (30%)
Query: 101 ITISHMQPADSGIYIC---------------DVNNPPDFLGQNQGILNVSVLVKPSKPLC 145
+ + ++ +D+G Y+C V+ PP +G ++ N+SV+ K
Sbjct: 2348 LQLKNIHVSDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEK------ 2401
Query: 146 SVQGRPETGHTISLSCLSALGTPSPVYYWHKLEGRDIVPVKENFNPTTGILVIGNLTNFE 205
+++SL+C A G P P W K D PV + + + IL G +
Sbjct: 2402 ---------NSVSLTC-EASGIPLPSITWFK----DGWPV--SLSNSVRILSGGRMLRLM 2445
Query: 206 Q------GYYQCTAINRLG 218
Q G Y C N G
Sbjct: 2446 QTTMEDAGQYTCVVRNAAG 2464
Score = 28.9 bits (63), Expect = 8.2
Identities = 32/152 (21%), Positives = 60/152 (39%), Gaps = 10/152 (6%)
Query: 196 LVIGNLTNFEQGYYQCTAINRLGNSSCEIDLTSSHPEVGIIVGALIGSLVGAAIIISVVC 255
L I +T ++G+Y+C A++ G + S P I V + G +++ +
Sbjct: 484 LDIAKVTLSDEGFYECIAVSSAGTGRAQTFFDVSEPPPVIQVPNNVTVTPGERAVLTCLI 543
Query: 256 FARNKAKAKAKERNSKTIAELEP---MTKINPRGESEAMPREDATQLEVTLPSSIHETGP 312
+ +RN + + EP T N E +++ DA + + S +
Sbjct: 544 ISAVDYNL-TWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAA 602
Query: 313 D---TIQEPDYEPKPTQEPAPEPAPGSEPMAV 341
T+QEP PK T P + G +++
Sbjct: 603 SVFLTVQEP---PKVTVMPKNQSFTGGSEVSI 631
>gi|4759066 sodium channel, voltage-gated, type II, beta [Homo
sapiens]
Length = 215
Score = 52.8 bits (125), Expect = 5e-07
Identities = 34/122 (27%), Positives = 66/122 (54%), Gaps = 6/122 (4%)
Query: 22 VQVTIPDGFVNVTVGSNVTLICIYTTT-VASREQLSIQWSFFHKKEM-EPISIYFSQGGQ 79
++VT+P +NV GS+ L C + + + +Q S+ W++ E + + F
Sbjct: 30 MEVTVP-ATLNVLNGSDARLPCTFNSCYTVNHKQFSLNWTYQECNNCSEEMFLQFRMKII 88
Query: 80 AVAIGQFKDRITGSNDPG--NASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVL 137
+ + +F+DR+ S +P + S+ + ++QP D GIY C + NPPD + G +++ VL
Sbjct: 89 NLKLERFQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNPPD-RHRGHGKIHLQVL 147
Query: 138 VK 139
++
Sbjct: 148 ME 149
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.133 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,543,885
Number of Sequences: 37866
Number of extensions: 1014054
Number of successful extensions: 9740
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 209
Number of HSP's successfully gapped in prelim test: 647
Number of HSP's that attempted gapping in prelim test: 6089
Number of HSP's gapped (non-prelim): 2909
length of query: 387
length of database: 18,247,518
effective HSP length: 104
effective length of query: 283
effective length of database: 14,309,454
effective search space: 4049575482
effective search space used: 4049575482
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.