Guide to the Human Genome
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Search of human proteins with 31982931

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31982931 SLC2A4 regulator [Homo sapiens]
         (387 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31982931 SLC2A4 regulator [Homo sapiens]                           804   0.0  
gi|76253910 zinc finger protein 704 [Homo sapiens]                    256   3e-68
gi|8923887 zinc finger protein 395 [Homo sapiens]                     178   8e-45
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    60   3e-09
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    52   1e-06
gi|154146199 sal-like 3 [Homo sapiens]                                 51   2e-06
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    50   5e-06
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    49   6e-06
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    49   8e-06
gi|237757312 synaptojanin 1 isoform c [Homo sapiens]                   48   1e-05
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         47   2e-05
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]         47   4e-05
gi|60460889 Myb protein P42POP [Homo sapiens]                          47   4e-05
gi|237757310 synaptojanin 1 isoform a [Homo sapiens]                   46   5e-05
gi|237757308 synaptojanin 1 isoform b [Homo sapiens]                   46   5e-05
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi...    46   5e-05
gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo s...    46   5e-05
gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo ...    46   5e-05
gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo ...    46   5e-05
gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo s...    46   5e-05
gi|40807452 peroxisome proliferator-activated receptor gamma, co...    46   6e-05
gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [...    46   6e-05
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    45   8e-05
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             45   1e-04
gi|7662302 TBK1 binding protein 1 [Homo sapiens]                       44   2e-04
gi|28376656 zinc finger, X-linked, duplicated B [Homo sapiens]         44   2e-04
gi|237757326 synaptojanin 1 isoform d [Homo sapiens]                   44   2e-04
gi|126090663 zinc finger homeodomain 4 [Homo sapiens]                  44   2e-04
gi|226371764 transcription factor 7-like 2 isoform 1 [Homo sapiens]    44   3e-04
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    43   4e-04

>gi|31982931 SLC2A4 regulator [Homo sapiens]
          Length = 387

 Score =  804 bits (2077), Expect = 0.0
 Identities = 387/387 (100%), Positives = 387/387 (100%)

Query: 1   MERPPPRAAGRDPSALRAEAPWLRAEGPGPRAAPVTVPTPPQGSSVGGGFAGLEFARPQE 60
           MERPPPRAAGRDPSALRAEAPWLRAEGPGPRAAPVTVPTPPQGSSVGGGFAGLEFARPQE
Sbjct: 1   MERPPPRAAGRDPSALRAEAPWLRAEGPGPRAAPVTVPTPPQGSSVGGGFAGLEFARPQE 60

Query: 61  SEPRASDLGAPRTWTGAAAGPRTPSAHIPVPAQRATPGKARLDEVMAAAALTSLSTSPLL 120
           SEPRASDLGAPRTWTGAAAGPRTPSAHIPVPAQRATPGKARLDEVMAAAALTSLSTSPLL
Sbjct: 61  SEPRASDLGAPRTWTGAAAGPRTPSAHIPVPAQRATPGKARLDEVMAAAALTSLSTSPLL 120

Query: 121 LGAPVAAFSPEPGLEPWKEALVRPPGSYSSSSNSGDWGWDLASDQSSPSTPSPPLPPEAA 180
           LGAPVAAFSPEPGLEPWKEALVRPPGSYSSSSNSGDWGWDLASDQSSPSTPSPPLPPEAA
Sbjct: 121 LGAPVAAFSPEPGLEPWKEALVRPPGSYSSSSNSGDWGWDLASDQSSPSTPSPPLPPEAA 180

Query: 181 HFLFGEPTLRKRKSPAQVMFQCLWKSCGKVLSTASAMQRHIRLVHLGRQAEPEQSDGEED 240
           HFLFGEPTLRKRKSPAQVMFQCLWKSCGKVLSTASAMQRHIRLVHLGRQAEPEQSDGEED
Sbjct: 181 HFLFGEPTLRKRKSPAQVMFQCLWKSCGKVLSTASAMQRHIRLVHLGRQAEPEQSDGEED 240

Query: 241 FYYTELDVGVDTLTDGLSSLTPVSPTASMPPAFPRLELPELLEPPALPSPLRPPAPPLPP 300
           FYYTELDVGVDTLTDGLSSLTPVSPTASMPPAFPRLELPELLEPPALPSPLRPPAPPLPP
Sbjct: 241 FYYTELDVGVDTLTDGLSSLTPVSPTASMPPAFPRLELPELLEPPALPSPLRPPAPPLPP 300

Query: 301 PPVLSTVANPQSCHSDRVYQGCLTPARLEPQPTEVGACPPALSSRIGVTLRKPRGDAKKC 360
           PPVLSTVANPQSCHSDRVYQGCLTPARLEPQPTEVGACPPALSSRIGVTLRKPRGDAKKC
Sbjct: 301 PPVLSTVANPQSCHSDRVYQGCLTPARLEPQPTEVGACPPALSSRIGVTLRKPRGDAKKC 360

Query: 361 RKVYGMERRDLWCTACRWKKACQRFLD 387
           RKVYGMERRDLWCTACRWKKACQRFLD
Sbjct: 361 RKVYGMERRDLWCTACRWKKACQRFLD 387


>gi|76253910 zinc finger protein 704 [Homo sapiens]
          Length = 412

 Score =  256 bits (653), Expect = 3e-68
 Identities = 161/354 (45%), Positives = 195/354 (55%), Gaps = 57/354 (16%)

Query: 85  SAHIPVPAQRATPGKARLDEVMAAAALTSLSTSPLLLGAPVAAFSPEPGLEPWKEALVRP 144
           S++I VP  R +  +  +D+V AA  LTSLSTSPL+   PV       G   WKE    P
Sbjct: 65  SSNIDVPPARKSSEELDMDKVTAAMVLTSLSTSPLVRSPPVRPNESLSG--SWKEGGCVP 122

Query: 145 PGSYSSSSNSGDWGWDLASDQSSPSTPSPPLPP-------------------EAAHFLFG 185
               SS+S+SG W W   SDQS+PSTPSPPL                     EA++ LF 
Sbjct: 123 ----SSTSSSGYWSWSAPSDQSNPSTPSPPLSADSFKPFRSPAQPDDGIDEAEASNLLFD 178

Query: 186 EPTLRKRKSPAQVMFQCLWKSCGKVLSTASAMQRHIRLVHLGRQAEPEQSDGEEDFYYTE 245
           EP  RKRK+  +VMF+CLWK+CGKVLSTA+ +Q+HIR +HLGR  + + SDGEEDFYYTE
Sbjct: 179 EPIPRKRKNSMKVMFKCLWKNCGKVLSTAAGIQKHIRTIHLGRVGDSDYSDGEEDFYYTE 238

Query: 246 LDVGVDTLTDGLSSLTPVSPTASM--PPAFP-----RLELPELLEPPALPSPLRPPAPPL 298
           + +  D++ DGLSSL PVSP+ S+  PP FP     R E P       L +PL   AP  
Sbjct: 239 IKLNTDSVADGLSSLAPVSPSQSLASPPTFPIPDSSRTETPCAKTETKLMTPLSRSAPTT 298

Query: 299 -----------PPPPVL---STVANPQSCHSDRVYQG---CLTPARLEPQPTEVGA---- 337
                        PPV    S    P        +Q      T   + P    VG     
Sbjct: 299 LYLVHTDHAYQATPPVTIPGSAKFTPNGSSFSISWQSPPVTFTGIPVSPTHHPVGTGEQR 358

Query: 338 --CPPALSS--RIGVTLRKPRGDAKKCRKVYGMERRDLWCTACRWKKACQRFLD 387
                 LSS  R  V+LRKPRG+ KKCRKVYGME RD+WCTACRWKKACQRFLD
Sbjct: 359 QHAHTVLSSPPRGTVSLRKPRGEGKKCRKVYGMENRDMWCTACRWKKACQRFLD 412


>gi|8923887 zinc finger protein 395 [Homo sapiens]
          Length = 513

 Score =  178 bits (451), Expect = 8e-45
 Identities = 141/392 (35%), Positives = 180/392 (45%), Gaps = 86/392 (21%)

Query: 70  APRTWTGAAAGPRTP-SAHIPVPAQRATPGKARLDEVMAAAALTSLSTSPLLLGAP--VA 126
           AP    GA A    P S +I VP +++      +DE+MAA  LTSLS SP++   P   A
Sbjct: 134 APPLEPGAQALAYRPVSRNIDVPKRKSDA--VEMDEMMAAMVLTSLSCSPVVQSPPGTEA 191

Query: 127 AFSPE-PGLEPWKEALVRPPGSYS---SSSNSGDWGWDLASDQSSPSTPSPPLP------ 176
            FS      +PWKE+     G  S   SS+ SG W     S  S  STPSPP P      
Sbjct: 192 NFSASRAACDPWKES-----GDISDSGSSTTSGHW-----SGSSGVSTPSPPHPQASPKY 241

Query: 177 -------PEAAH--------FLFGEPTLRKRKSPAQVMFQCLWKSCGKVLSTASAMQRHI 221
                  P+  H        FL  EP  RKRK+  +VM++CLW +CGKVL +   ++RH+
Sbjct: 242 LGDAFGSPQTDHGFETDPDPFLLDEPAPRKRKNSVKVMYKCLWPNCGKVLRSIVGIKRHV 301

Query: 222 RLVHLGRQAEPEQSDGEEDFYYTELDVGVDTLTDGLSSL--TPVSPTASMPPA------- 272
           + +HLG   + +Q   EEDFYYTE+ +  ++     ++   TPV  T +  PA       
Sbjct: 302 KALHLGDTVDSDQFKREEDFYYTEVQLKEESAAAAAAAAAGTPVPGTPTSEPAPTPSMTG 361

Query: 273 FPRLELPELLEPPALPSPLRPPAPPLPPPPVLSTVANPQSCH--SDRVYQG--------- 321
            P   LP  L       P  P      P   LS  A     H  +D  YQ          
Sbjct: 362 LPLSALPPPLHKAQSSGPEHPGPESSLPSGALSKSAPGSFWHIQADHAYQALPSFQIPVS 421

Query: 322 -----------------CLTPARLEPQP-TEVGACPPALSSRIGVT--------LRKPRG 355
                             L+P R      +E     PA+ S + VT         RK RG
Sbjct: 422 PHIYTSVSWAAAPSAACSLSPVRSRSLSFSEPQQPAPAMKSHLIVTSPPRAQSGARKARG 481

Query: 356 DAKKCRKVYGMERRDLWCTACRWKKACQRFLD 387
           +AKKCRKVYG+E RD WCTACRWKKACQRFLD
Sbjct: 482 EAKKCRKVYGIEHRDQWCTACRWKKACQRFLD 513


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 87/318 (27%), Positives = 117/318 (36%), Gaps = 46/318 (14%)

Query: 1   MERPPPRAAGRDPSALRAEAPWLRAEGPGPRAAPVTVPTPPQGSSVGGGFAGLEFARPQE 60
           + RP P A  R P+    E P          +     P   +  S GGG   L+    + 
Sbjct: 180 LPRPAPSARPRPPT----EGPRKSVSSASEHSTTEPSPAARRRPSAGGG---LQRPASRS 232

Query: 61  SEPRASDLGAPRTWTGAAAG----PRTPSAHIPVPAQRATPGKARLDEVMAAAALTSLST 116
               A+ L +P     +A G    P  PS   P   Q   P +       AA AL  LS+
Sbjct: 233 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 292

Query: 117 SPLLLGAPVAAFSPEPGLEPWKEALVRPPGSYSSSSNSGDWGWDLASDQS-SPSTPSPPL 175
           SPL   +P A   P P   P  + L  PP +  S + +      L +  S  PS P  PL
Sbjct: 293 SPLATPSPSA--PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPL 350

Query: 176 ---PPEAAHFLFGEPTLRKRKSPAQVMFQCLWKSCGKVLSTASAMQRHIRLVHLGRQ--A 230
              PP+A   L   P       PA              L+T S    +   VHL +   +
Sbjct: 351 ATPPPQAPPALALPPLQAPPSPPASPPL--------SPLATPSPQAPNALAVHLLQAPFS 402

Query: 231 EPEQSDGEEDFYYTELDVGVDTLTDGLSSLTPVSPTASMP-PAFPRLELPELLEPPALPS 289
            P     +  F                 +  PVSP+A+ P  A P L  P L  PP+ P+
Sbjct: 403 PPPSPPVQAPF--------------SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA 448

Query: 290 --PLRPPA--PPLPPPPV 303
             P+ P A  PP  PPP+
Sbjct: 449 SPPMSPSATPPPQAPPPL 466



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 93/383 (24%), Positives = 125/383 (32%), Gaps = 117/383 (30%)

Query: 28  PGPRAAPV--TVP----TPPQGSSVGGGFAGLEFARPQESEPRASDLGAPRTWTGAAAGP 81
           P P A P   T+P    TPP  ++   G   L+        P  S L  P         P
Sbjct: 304 PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP--------P 355

Query: 82  RTPSAHIPVPAQRATPGKARLDEVMAAAALTSLSTSPLLLGAPVAAFSPEPGLEPWKEAL 141
           + P A + +P  +A P       +   A  +  + + L +    A FSP P   P  +A 
Sbjct: 356 QAPPA-LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS--PPVQAP 412

Query: 142 VRPPGSYSSSSNSGDWGWDLASDQSSPSTPSPPL-----------------PPEAAHFLF 184
             PP S   S ++          Q+ PS  +PPL                 PP  A    
Sbjct: 413 FSPPASPPVSPSA------TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL 466

Query: 185 GEPTLRKRKSPAQVMFQCLWKSCGKVLSTASAMQRHIRLVHLGRQAEPEQSDGEEDFYYT 244
             P L+  K P Q             L+T                + P    G+  F   
Sbjct: 467 AAPPLQLAKPPPQAP---------PALATPPLQ---------ALPSPPASFPGQAPF--- 505

Query: 245 ELDVGVDTLTDGLSSLTPVSPTASMPPAFPRLELPELLE----PPALP---SPLRPPAP- 296
                        S+  P+SP A+ PP  P +    LL+    PPA P   +P RPP P 
Sbjct: 506 -----------SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG 554

Query: 297 ---------------PLPPPP----VLSTVANPQ-SCHSDRVYQGCLTPARLE------- 329
                          P PPPP      ST++ P  + HS        TP  L        
Sbjct: 555 PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS---SATSTPEELRGYDSGPE 611

Query: 330 -------PQPTEVGACPPALSSR 345
                  P   E+ AC PA  SR
Sbjct: 612 GGAAASPPPDAELAACHPAAWSR 634



 Score = 37.7 bits (86), Expect = 0.018
 Identities = 49/185 (26%), Positives = 66/185 (35%), Gaps = 38/185 (20%)

Query: 4   PPPRAAGRDPSALRAE--APWLRAEGPGPRAAPVTVP--TPPQGSSVGGGFAGLEFARPQ 59
           PP   +   PS       AP L+   P P A+P   P  TPP  +        L+ A+P 
Sbjct: 419 PPVSPSATPPSQAPPSLAAPPLQVP-PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP 477

Query: 60  ESEPRASDL-------GAPRTWTGAAAGPRTPSAHIPVPAQRATPGKARLDEVMAAAALT 112
              P A            P ++ G A  P +PSA +P+      P +A            
Sbjct: 478 PQAPPALATPPLQALPSPPASFPGQA--PFSPSASLPMSPLATPPPQA------------ 523

Query: 113 SLSTSPLLLGAPVAAFSPEPGLEPWKEALVRPPGSYSSSSNSGDWGWDLASDQSSPSTPS 172
                P +L AP+    P P   P  +A  RPP     +S SG          +    P 
Sbjct: 524 -----PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG-------PRLTLALAPG 571

Query: 173 PPLPP 177
           PP PP
Sbjct: 572 PPPPP 576


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 90/382 (23%), Positives = 127/382 (33%), Gaps = 64/382 (16%)

Query: 1   MERPPPRAAGRDPSALRAEAPWLRAEGPGPRAAPVTVPTPPQGSSVGGGFAGLEFARPQE 60
           ++RP  R+     + L + A      GP  R  P     P Q         GL+  RP +
Sbjct: 234 LQRPASRSLSSSATPLSSPA----RSGPSARGTPRAPAHPSQPKP-----KGLQALRPPQ 284

Query: 61  SEPRASDLGAPRTWTGAAAGPRTPSAHIPVPAQRATPGKARLDEVMAAAALTSLSTSPLL 120
             P       PR     A GP + S+ +  P+   T  +       AA  L +       
Sbjct: 285 VTP-------PRKDAAPALGPLS-SSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPP 336

Query: 121 LGAPVAAFSPEPGLEPWKEALVRPPGSYSSSSNSGDWGWDLASDQSSPSTPSPP----LP 176
           L  P+    P P   P  + L  PP +  S +             ++P   +PP    +P
Sbjct: 337 LATPLPLAPPSPSAPPSLQTLPSPPATPPSQA---------PPSMTTPPMQAPPSLQTIP 387

Query: 177 PEAAHFLFGEPTLRKRKSPAQVMFQCLWKSCGKV-------LSTASAMQRHIRLVHLGRQ 229
           P         P+L+   SP  +       S G           T S  Q    L    R 
Sbjct: 388 PIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRP 447

Query: 230 AE--PEQSDGEEDF-------YYTELDVGVDTLTD--------GLSSLTPVSPTASMPPA 272
           A   P+    +            T L   V  L+          LSSL   SP A +   
Sbjct: 448 ASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSL 507

Query: 273 F-PRLELPELLEPPALPSP----LRPPA---PPLPPPPVLSTVANPQSCHSDRVYQGCLT 324
             P LE    L PP+L +P      PP    P L PPP+ +  A   + H +     C  
Sbjct: 508 IMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLET--PPCPA 565

Query: 325 PARLEPQPTEVGACPPALSSRI 346
           P  L+  P+ +   PP   S I
Sbjct: 566 PCPLQAPPSPLTTPPPETPSSI 587



 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 97/369 (26%), Positives = 127/369 (34%), Gaps = 76/369 (20%)

Query: 4   PPPRAAGRDPSALRAEAPWLRAEGPG--PRAAPVTVPTPPQGSSVGGGFAGLEFARPQES 61
           PP     + P +L A  P   +  P   P ++P+T+  P Q  S          A     
Sbjct: 451 PPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIH-PLQALS--------SLASHSPQ 501

Query: 62  EPRASDLGAPRTWTGAAAGP--RTPSAHIPVPAQRATPGKARLDEVMAAAALTS--LSTS 117
            P +S +  P     + A P  +TP A +  P     P  A      A+A LT+  L T 
Sbjct: 502 APLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETP 561

Query: 118 PLLLGAPVAAFSPEPGLEPWKEALVRPPGSYSSSSNSGDWGWDLASDQSSPSTPSPPL-- 175
           P     P+ A  P P   P       PP + SS +          +       PSPPL  
Sbjct: 562 PCPAPCPLQA-PPSPLTTP-------PPETPSSIATPPPQAPPALASPPLQGLPSPPLSP 613

Query: 176 ----PPEAAHFLFGEPTLRKRKSPAQVMFQCLWKSCGKVLSTASAMQRHIRLVHLGRQ-- 229
               PP+A   L   P       PA              L+T S    +   VHL +   
Sbjct: 614 LATPPPQAPPXLALPPLQAPPSPPASPPLS--------PLATPSPQAPNALAVHLLQAPF 665

Query: 230 AEPEQSDGEEDFYYTELDVGVDTLTDGLSSLTPVSPTASMP-PAFPRLELPELLEPP--- 285
           + P     +  F                 +  PVSP+A+ P  A P L  P L  PP   
Sbjct: 666 SPPPSPPVQAPF--------------SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 711

Query: 286 --------ALPSPLRPP---APPL--PPPPVLSTVANPQSCHSDRVYQGCLTPARLEPQP 332
                   A P P  PP   APPL  PP P  S   +P +    RV      P  L   P
Sbjct: 712 ASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV------PPLLAAPP 765

Query: 333 TEVGACPPA 341
            +V   PPA
Sbjct: 766 LQVPPSPPA 774



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 95/366 (25%), Positives = 125/366 (34%), Gaps = 53/366 (14%)

Query: 5   PPRAAGRDPSALRAEAPWLRAEGPGPRAAPVTVPTPPQGSSVGGGFAGLEFARPQESEPR 64
           PPR          + +P       G +A PV    PP  ++       L    P  S P 
Sbjct: 287 PPRKDAAPALGPLSSSPLATPSPSGTKARPVP---PPDNAATP-----LPATLPP-SPPL 337

Query: 65  ASDL-------GAPRTWTGAAAGPRTPSAHIP----VPAQRATPGKARLDEVMAAAALTS 113
           A+ L        AP +     + P TP +  P     P  +A P    +  +    +LTS
Sbjct: 338 ATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTS 397

Query: 114 LST----SPLLLGAPVAAFS-PEPGLEPWKEALVRPPGSYSSSSNSGDWGWDLASDQSSP 168
            S     SPL L +  A  S   P L+     L   P    +S         L S     
Sbjct: 398 PSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQAS---------LTSPSRPA 448

Query: 169 STPSPPLPPEAAHFLFGEPTLRKRKSPAQVMFQCLWKSCGKVLSTASAMQRHIRLVHLGR 228
           STP    P +A   L   P L+   SPA              L   S++  H     L  
Sbjct: 449 STPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTI--HPLQALSSLASHSPQAPLSS 506

Query: 229 QAEPEQSDGEEDFYYTELDVGVDTLT----DGLSSLTPVS-PTASMPPAFPRLELPELLE 283
              P   + +       L     +LT    + L SL P    TAS P   P LE P    
Sbjct: 507 LIMPPL-ETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETP---- 561

Query: 284 PPALPSPLRPPAPPL--PPPPVLSTVANP----QSCHSDRVYQGCLTPARLEPQPTEVGA 337
           P   P PL+ P  PL  PPP   S++A P        +    QG  +P  L P  T    
Sbjct: 562 PCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPP-LSPLATPPPQ 620

Query: 338 CPPALS 343
            PP L+
Sbjct: 621 APPXLA 626



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 95/393 (24%), Positives = 126/393 (32%), Gaps = 91/393 (23%)

Query: 4   PPPRAAGRDPSALRAEAPWLRAEGPGPRAAPVTVPTPPQGSSVGGGFAGLEFARPQESEP 63
           PPP+A    P AL +  P L+   P P  +P+   TPP  +        L+      + P
Sbjct: 590 PPPQA----PPALAS--PPLQGL-PSPPLSPLA--TPPPQAPPXLALPPLQAPPSPPASP 640

Query: 64  RASDLGAPRTWTGAAAG------PRTPSAHIPVPAQRATPGKARLDEVMAAAALTSLSTS 117
             S L  P      A        P +P    PV A  + P    +     + + T  S +
Sbjct: 641 PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV-----SPSATPPSQA 695

Query: 118 PLLLGAPVAAFSPEPGLEPWKEALVRPPGSYSSSSNSGDWGWDLASDQSSPSTPSPPLPP 177
           P  L AP     P P   P       PP        +       +   S P +PS   PP
Sbjct: 696 PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPP 755

Query: 178 EAAHFLFGEPTLRKRKSPAQVMFQCLWK---SCGKVLSTASAMQRHIRLVHLGRQAEPEQ 234
                L   P       PA +    L K        L+T                + P  
Sbjct: 756 RVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQ---------ALPSPPAS 806

Query: 235 SDGEEDFYYTELDVGVDTLTDGLSSLTPVSPTASMPPAFPRLELPELLE----PPALP-- 288
             G+  F                S+  P+SP A+ PP  P +    LL+    PPA P  
Sbjct: 807 FPGQAPF--------------SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL 852

Query: 289 -SPLRPPAP----------------PLPPPP----VLSTVANPQ-SCHSDRVYQGCLTPA 326
            +P RPP P                P PPPP      ST++ P  + HS        TP 
Sbjct: 853 QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS---SATSTPE 909

Query: 327 RLE--------------PQPTEVGACPPALSSR 345
            L               P   E+ AC PA  SR
Sbjct: 910 ELRGYDSGPEGGAAASPPPDAELAACHPAAWSR 942



 Score = 38.5 bits (88), Expect = 0.010
 Identities = 48/186 (25%), Positives = 68/186 (36%), Gaps = 36/186 (19%)

Query: 2   ERPPPRAAG--RDPSALRAEAPWLRAEGPGPRAAPVTV-------PTPPQGSSVGGGFAG 52
           + PPP AA   + P +  A  P   +  P PR  P+         P+PP    +      
Sbjct: 725 QAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKP 784

Query: 53  LEFARPQESEPRASDLGAP-RTWTGAAAGPRTPSAHIPVPAQRATPGKARLDEVMAAAAL 111
              A P  + P    L +P  ++ G A  P +PSA +P+      P +A           
Sbjct: 785 PPQAPPALATPPLQALPSPPASFPGQA--PFSPSASLPMSPLATPPPQA----------- 831

Query: 112 TSLSTSPLLLGAPVAAFSPEPGLEPWKEALVRPPGSYSSSSNSGDWGWDLASDQSSPSTP 171
                 P +L AP+    P P   P  +A  RPP     +S SG          +    P
Sbjct: 832 ------PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG-------PRLTLALAP 878

Query: 172 SPPLPP 177
            PP PP
Sbjct: 879 GPPPPP 884


>gi|154146199 sal-like 3 [Homo sapiens]
          Length = 1300

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 92/381 (24%), Positives = 133/381 (34%), Gaps = 55/381 (14%)

Query: 1   MERPPPRAAGRDPSALRAEAPWLRAEGPGPRAAPVTVPTPPQGSSVGGGFAGLEFARPQE 60
           M+RPPPR     PS   A AP   A GP P   P     P    +     AG   A P  
Sbjct: 233 MQRPPPR-----PSLSPAAAP--SAPGPAPSQLPGLAALPLSAGAPAAAIAGSGPAAPAA 285

Query: 61  SEPRASDLGAPRTWTGAAAGPRTPSAHIPVPA--QRATPGKARLDEVMAAAALTSLSTSP 118
            E  A  L  P +      GP  PSA     A    A P  A   +  A++   S ST P
Sbjct: 286 FEG-AQPLSRPESGASTPGGPAEPSAPAAPSAAPAPAAPAPAPAPQSAASSQPQSASTPP 344

Query: 119 LLLGAPVAAFSPEPGLEPWKEALVRPPGSYSSSSNSGDWGWDLASDQSSPSTPSPPLPPE 178
            L  AP +     PGL         P      +S SG    +     ++ +    PL   
Sbjct: 345 AL--APGSLLGAAPGL---------PSPLLPQTSASGVIFPNPLVSIAATANALDPLSAL 393

Query: 179 AAHFLFGEPTL---RKRKSPAQVMFQCLWKSCGKVLSTASAMQRHIRLVHLGRQAEPEQS 235
             H     P +     + S     F+   + C KV  + SA+Q H+R  H G +      
Sbjct: 394 MKHRKGKPPNVSVFEPKASAEDPFFKHKCRFCAKVFGSDSALQIHLR-SHTGERPFKCNI 452

Query: 236 DG----------------EEDFYYTELD-VGVDTLTDGLSSLTPVSPTASMPPAFPRLEL 278
            G                +E + + +++   V    D + + + +    S+PP  P    
Sbjct: 453 CGNRFSTKGNLKVHFQRHKEKYPHIQMNPYPVPEYLDNVPTCSGIPYGMSLPPEKP--VT 510

Query: 279 PELLEPPALPSPLRPPAPPLPP--PPVLSTVANPQSCHSDRVYQGCLTPARLEPQPTEVG 336
             L   P LP+        LPP  P       +P +  + R      +P R  P  +E  
Sbjct: 511 TWLDSKPVLPTVPTSVGLQLPPTVPGAHGYADSPSATPASR------SPQRPSPASSECA 564

Query: 337 ACPPALS---SRIGVTLRKPR 354
           +  P L+   S +  T   P+
Sbjct: 565 SLSPGLNHVESGVSATAESPQ 585



 Score = 33.1 bits (74), Expect = 0.44
 Identities = 33/120 (27%), Positives = 50/120 (41%), Gaps = 6/120 (5%)

Query: 189 LRKRKSPAQVMFQCLWKSCGKVLSTASAMQRHIRLVHLGRQAEPEQSDGEEDFYYTELDV 248
           + + K P +V   C    C K  + A  +Q+HIR+   G+       +G +D   +EL  
Sbjct: 728 VHRAKPPLRVQHSC--PICQKKFTNAVVLQQHIRMHMGGQIPNTPLPEGFQDAMDSELAY 785

Query: 249 GVDTLTDGLSSLTPVSPTASMPPAFPRLELPELLEPPALPSPLRPPAPPLPPPPVLSTVA 308
             D   + LSS        SM       EL +    PA P      + P  PP V+S++A
Sbjct: 786 D-DKNAETLSSYDDDMDENSME---DDAELKDAATDPAKPLLSYAGSCPPSPPSVISSIA 841



 Score = 30.0 bits (66), Expect = 3.7
 Identities = 23/62 (37%), Positives = 30/62 (48%), Gaps = 9/62 (14%)

Query: 168  PSTPSPPLPPEAAHFLFGEPTLRKRKSPAQVMFQCLWKSCGKVLSTASAMQRHIRLVHLG 227
            P+ P   + P  A  L   P    R++P Q   Q    SCGK  S+ASA+Q H R  H G
Sbjct: 1087 PAGPQTVMGPGLAPMLAPPP----RRTPKQHNCQ----SCGKTFSSASALQIHER-THTG 1137

Query: 228  RQ 229
             +
Sbjct: 1138 EK 1139


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 41/130 (31%), Positives = 53/130 (40%), Gaps = 30/130 (23%)

Query: 231 EPEQSDGEEDFYYTELDVGVDTLTDGLSSLTPVSPTASMPPAF------------PRLEL 278
           + E++   E    ++ D  V  + +GL  L P  P+ + PP              P  E 
Sbjct: 769 DKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVPAKEE 828

Query: 279 PELLEPPALPSPLRPPAPPLPPPPVLSTVANPQSCHSDRVYQGCLTPARLEPQPTEVGAC 338
           PE  E PA P PL PP P  PPPPV   V  P              P +L P+ T  G  
Sbjct: 829 PE--ELPAAPGPLPPPPP--PPPPVPGPVTLP--------------PPQLVPEGTPGGGG 870

Query: 339 PPALSSRIGV 348
           PPAL   + V
Sbjct: 871 PPALEEDLTV 880



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 29/92 (31%), Positives = 34/92 (36%), Gaps = 18/92 (19%)

Query: 260 LTPVSPTASMPPAFPRLELPELLEPPALPSPLRPPAPPLPPPPVLSTV-----ANPQSCH 314
           L P+ PT   P   P         PP  PSP R  APP  PP  + +V     A P    
Sbjct: 638 LQPMGPTCPTPAPVP---------PPEAPSPFR--APPFHPPGPMPSVGSMPSAGPMPSA 686

Query: 315 SDRVYQGCLTPARLEPQPT--EVGACPPALSS 344
                 G +  AR  P  T   +G   P L S
Sbjct: 687 GPMPSAGPVPSARPGPPTTANHLGLSVPGLVS 718



 Score = 29.6 bits (65), Expect = 4.8
 Identities = 20/63 (31%), Positives = 29/63 (46%), Gaps = 3/63 (4%)

Query: 229  QAEPEQSDGEEDFYYTEL-DVGVDTLTDGLSSLTPVSPTASMPPAFPRLELPELLEPPAL 287
            + E E+ D EE+    E+ D+   T    +    P  PT  +PPA P  E P  ++P   
Sbjct: 943  EEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPT--LPPALPPPESPPKVQPEPE 1000

Query: 288  PSP 290
            P P
Sbjct: 1001 PEP 1003


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 84/336 (25%), Positives = 108/336 (32%), Gaps = 76/336 (22%)

Query: 16  LRAEAPWLRAEGPGPRAAPVTVPTPPQGSSVGGGFAGLEFARPQESEPRASD----LGAP 71
           L    P +RA   G     V   +P        G AG   A P E  P A+      G  
Sbjct: 43  LAPRTPEVRAAAAGALGNHVVSGSP-------AGAAGAGPAAPAEGAPGAAPEPPPAGRA 95

Query: 72  RTWTGAAAGPRTPSAHIPVPAQRATPGKARLDEVMAAAALTSLSTSPLLLGAPVAAFSPE 131
           R   G    P  PS   P+      P  A+L      +A    S +P+   A VAA    
Sbjct: 96  RPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAG---SCAPVPAAAAVAA---- 148

Query: 132 PGLEPWKEALVRPPGSYSSSSNSGDWGWDLASDQSSPSTPSPPLPPEAAHFLFGEPTLRK 191
            G EP      +P G  + ++ +G            P  P  P  P AA  L G   L  
Sbjct: 149 -GPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPG-PGKPAGPGAAQTLNGSAAL-- 204

Query: 192 RKSPAQVMFQCLWKSCGKVLSTASAMQRHIRLVHLGRQAEPEQSDGEEDFYYTELDVGVD 251
                              L++  A    + LV+ G  A               L     
Sbjct: 205 -------------------LNSHHAAAPAVSLVNNGPAA---------------LLPLPK 230

Query: 252 TLTDGLSSLTPVSPTASMPPAFPRLELPELLEPPALPSPLRPPAPPLPPPPVLSTVANPQ 311
               G    TP    A+ PPA      P    PPA P+P  P A P PPPP  +T+A P 
Sbjct: 231 PAAPGTVIQTPPFVGAAAPPA------PAAPSPPAAPAPAAPAAAPPPPPPAPATLARP- 283

Query: 312 SCHSDRVYQGCLTPARLEPQPTEVGACPPALSSRIG 347
                        P      PT   A PP  +++ G
Sbjct: 284 -------------PGHPAGPPTAAPAVPPPAAAQNG 306



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 53/179 (29%), Positives = 67/179 (37%), Gaps = 36/179 (20%)

Query: 5   PPRAAGRDPSALRAEAPWLRAEGPGPRAAPVTVPTPPQGSSVGGGFAGLEFARPQESEPR 64
           P + AG  P+AL A A      GPGP   P   P P  G   G G A       Q     
Sbjct: 157 PAKPAG--PAALAARA------GPGPGPGPGPGPGPGPGKPAGPGAA-------QTLNGS 201

Query: 65  ASDLGAPRTWTGAAAGPRT-PSAHIPVPAQRATPGKARLDE--VMAAAALTSLSTSPLLL 121
           A+ L +      A +     P+A +P+P + A PG        V AAA     + SP   
Sbjct: 202 AALLNSHHAAAPAVSLVNNGPAALLPLP-KPAAPGTVIQTPPFVGAAAPPAPAAPSPPAA 260

Query: 122 GAPVAAFSPEPGLEPWKEALVRPPGSYSSSSNSGDWGWDLASDQSSPSTPSPPLPPEAA 180
            AP A  +  P   P    L RPPG                   + P T +P +PP AA
Sbjct: 261 PAPAAPAAAPPPPPPAPATLARPPG-----------------HPAGPPTAAPAVPPPAA 302



 Score = 38.5 bits (88), Expect = 0.010
 Identities = 55/199 (27%), Positives = 68/199 (34%), Gaps = 29/199 (14%)

Query: 4   PPPRAAGRDPSALRAEAPWLRAEGPGPRAAPVTV----------PT-----PPQGSSVGG 48
           PP  AA   P+A    AP   A  P P  AP T+          PT     PP  ++  G
Sbjct: 249 PPAPAAPSPPAAPAPAAP--AAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNG 306

Query: 49  GFAGLEFARPQESEPRASDLGAPRTWTGAAAGPRTPSAHIPVP---AQRATPGKARLDEV 105
           G AG   A    +   A   G P    GAAA    P      P    Q A P    L   
Sbjct: 307 GSAGAAPAPAPAAGGPAGVSGQP--GPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAAS 364

Query: 106 MAAAALTSLSTSPLLLGA---PVAAFSPEP----GLEPWKEALVRPPGSYSSSSNSGDWG 158
             A+   S+   P + GA   P A   P P    GL       V    S + ++ +    
Sbjct: 365 GPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIR 424

Query: 159 WDLASDQSSPSTPSPPLPP 177
             L     +P  P PP  P
Sbjct: 425 ATLTPTVLAPRLPQPPQNP 443



 Score = 35.0 bits (79), Expect = 0.11
 Identities = 74/322 (22%), Positives = 111/322 (34%), Gaps = 62/322 (19%)

Query: 1   MERPPPRAAGRDPSALRAEAPWLRAEGPGPRAAPVTVPTPPQGSSVGGGFAGLEFARPQE 60
           ++ PP   A   P+      P      P P AAP   P PP                   
Sbjct: 238 IQTPPFVGAAAPPAPAAPSPP----AAPAP-AAPAAAPPPP------------------- 273

Query: 61  SEPRASDLGAPRTWTGAAAGPRTPSAHIPVPAQRATPGKARLDEVMAAAA--LTSLSTSP 118
             P  + L  P    G  AGP T +  +P PA     G A      A AA     +S  P
Sbjct: 274 -PPAPATLARP---PGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQP 329

Query: 119 LLLGAPVAAFSPEPGLE---PWKEALVRPPGSY-------SSSSNSGDWGWDLASDQSSP 168
              G   AA +P PG++   P +     PP +        +S++ S   G  +     SP
Sbjct: 330 ---GPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSP 386

Query: 169 STPSPPLPPEAAHFLFGEPTLRKRKSPAQVMFQCLWKSCGKVLSTASAMQRHIRLVHLGR 228
           +   PP P        G PT    K  A  + Q L ++     +T S ++  +    L  
Sbjct: 387 AAVPPPAP--------GTPT-GLPKGAAGAVTQSLSRT---PTATTSGIRATLTPTVLAP 434

Query: 229 QAEPEQSDGEEDFYYTELDVGVDTLTDGLSSLTPVSPTASMPPAFPRLELPELLEPPALP 288
           +  P+      +    +L  G+  +      L  +        A  +++     +P    
Sbjct: 435 RL-PQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIP-----QQALAQMQAQAHAQPQTTM 488

Query: 289 SPLRPPAPPLPPPPVLSTVANP 310
           +P RP  P   PP  +STV  P
Sbjct: 489 AP-RPATPTSAPPVQISTVQAP 509


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 90/368 (24%), Positives = 118/368 (32%), Gaps = 96/368 (26%)

Query: 1   MERPPPRAAGRDPSALRAEAPWLRAEGPGPRAAPVTVPTPPQGSSVGGGFAGLEFARPQE 60
           + RP P A  R P+    E P          +     P   +  S GGG   L+    + 
Sbjct: 189 LPRPAPSARPRPPT----EGPRKSVSSASEHSTTEPSPAARRRPSAGGG---LQRPASRS 241

Query: 61  SEPRASDLGAPRTWTGAAAG----PRTPSAHIPVPAQRATPGKARLDEVMAAAALTSLST 116
               A+ L +P     +A G    P  PS   P   Q   P +       AA AL  LS+
Sbjct: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301

Query: 117 SPLLLGAPVAAFSPEPGLEPWKEALVRPPGSYSSSSNSGDWGWDLASDQSSPSTPSPPLP 176
           SPL   +P AA   +             P +  ++ +S      LA       TP P  P
Sbjct: 302 SPLATPSPSAALQSQA------------PPTLPATPHSSSLTCQLA-------TPLPLAP 342

Query: 177 PEAAHFLFGEPTLRKRKSPAQVMFQCLWKSCGKVLSTASAMQRHIRLVHLGRQAEPEQSD 236
           P  +      P+L+   SP                                    P Q+ 
Sbjct: 343 PSPS----APPSLQTLPSPPAT--------------------------------PPSQAT 366

Query: 237 GEEDFYYTELDVGVDTLTDGLSSLTPVSPTASMPP-AFPRLELPELLEPPALP-----SP 290
                  T L       T       P+SP A+ PP A P L LP L  PP+ P     SP
Sbjct: 367 -------TSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSP 419

Query: 291 LRPPAP----------------PLPPPPVLSTVANPQSCH-SDRVYQGCLTPARLEPQPT 333
           L  P+P                P P PPV +  + P S   S         P  L   P 
Sbjct: 420 LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPL 479

Query: 334 EVGACPPA 341
           +V   PPA
Sbjct: 480 QVPPSPPA 487



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 100/410 (24%), Positives = 135/410 (32%), Gaps = 118/410 (28%)

Query: 2   ERPPPRAAGRDPSALRAE-APWLRAEGPGPRAAPV--TVP----TPPQGSSVGGGFAGLE 54
           + PP   A    S+L  + A  L    P P A P   T+P    TPP  ++   G   L+
Sbjct: 316 QAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQ 375

Query: 55  FARPQESEPRASDLGAPRTWTGAAAGPRTPSAHIPVPAQRATPGKARLDEVMAAAALTSL 114
                   P  S L  P         P+ P A + +P  +A P       +   A  +  
Sbjct: 376 ATHSFLPSPPLSPLATPP--------PQAPPA-LALPPLQAPPSPPASPPLSPLATPSPQ 426

Query: 115 STSPLLLGAPVAAFSPEPGLEPWKEALVRPPGSYSSSSNSGDWGWDLASDQSSPSTPSPP 174
           + + L +    A FSP P   P  +A   PP S   S ++          Q+ PS  +PP
Sbjct: 427 APNALAVHLLQAPFSPPPS--PPVQAPFSPPASPPVSPSA------TPPSQAPPSLAAPP 478

Query: 175 L-----------------PPEAAHFLFGEPTLRKRKSPAQVMFQCLWKSCGKVLSTASAM 217
           L                 PP  A      P L+  K P Q             L+T    
Sbjct: 479 LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP---------PALATPPLQ 529

Query: 218 QRHIRLVHLGRQAEPEQSDGEEDFYYTELDVGVDTLTDGLSSLTPVSPTASMPPAFPRLE 277
                       + P    G+  F                S+  P+SP A+ PP  P + 
Sbjct: 530 ---------ALPSPPASFPGQAPF--------------SPSASLPMSPLATPPPQAPPVL 566

Query: 278 LPELLE----PPALP---SPLRPPAP----------------PLPPPP----VLSTVANP 310
              LL+    PPA P   +P RPP P                P PPPP      ST++ P
Sbjct: 567 AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 626

Query: 311 Q-SCHSDRVYQGCLTPARLE--------------PQPTEVGACPPALSSR 345
             + HS        TP  L               P   E+ AC PA  SR
Sbjct: 627 DLAGHSS---SATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR 673



 Score = 29.6 bits (65), Expect = 4.8
 Identities = 29/102 (28%), Positives = 39/102 (38%), Gaps = 18/102 (17%)

Query: 258 SSLTPVSPTASM----PPAFPRLELPELLEPP-ALPSPLRPPAPPLPPPPVLSTVANPQS 312
           S L   SP+A++    PP  P       L    A P PL PP+P  PP   L T+ +P +
Sbjct: 302 SPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPS--LQTLPSPPA 359

Query: 313 CHSDRVYQGCLTPA-----------RLEPQPTEVGACPPALS 343
               +      +P             L P  T     PPAL+
Sbjct: 360 TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA 401


>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
          Length = 1295

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 47/160 (29%), Positives = 65/160 (40%), Gaps = 16/160 (10%)

Query: 2    ERPPPRAAGRDPSALRAEAPWLRAEGPGPRAAPVTVPTPPQGSSVGGGFAGLEFARPQES 61
            +RPPP +  R P+  R E    ++ G   +         PQ    G G AG   ARP   
Sbjct: 1124 QRPPPPSGARSPAPTRKEFGAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARP-TI 1182

Query: 62   EPRASDLGAPRTWTGAAAGPRTPSAHIPVPAQRATPGKARLDEVMAAAALTSLSTS---- 117
             PRA  + AP++   A+AG  TP +         + G   L E +   A     +S    
Sbjct: 1183 PPRAGVISAPQSHARASAGRLTPESQ--SKTSETSKGSTFLPEPLKPQAAFPPQSSLPPP 1240

Query: 118  ------PLLLGAPVAAFSPEPGLEPWKEALVRPPGSYSSS 151
                  PL+   PVAA  P+ G +P  E   +PP    SS
Sbjct: 1241 AQRLQEPLV---PVAAPMPQSGPQPNLETPPQPPPRSRSS 1277



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 69/272 (25%), Positives = 89/272 (32%), Gaps = 46/272 (16%)

Query: 61   SEPRASDLGAPRTWTGAAAGPRTPSAHIPVPAQRATPGKARLDEVMAAAALTSLSTSPLL 120
            S PR S   +P    G    P  P      P++   P  A+   + A  A       P  
Sbjct: 1044 SSPRTSPCQSPTISEGPV--PSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQ 1101

Query: 121  LGAPVAAFSPEPGLEPWKEALV-RPP---GSYSSSSNSGDWGWDLA-----SDQSSPSTP 171
               P     P P   P + A   RPP   G+ S +    ++G   +      D    S P
Sbjct: 1102 PLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGAPKSPGTTRKDNIGRSQP 1161

Query: 172  SPPLP---PEAAHFLFGEPTLRKRKSPAQVMFQCLWKSCGKVLSTASAMQRHIRLVHLGR 228
            SP      P  A +    PT+  R                      SA Q H R    GR
Sbjct: 1162 SPQAGLAGPGPAGYSTARPTIPPRAG------------------VISAPQSHAR-ASAGR 1202

Query: 229  QAEPEQSDGEEDFYYTELDVGVDTLTDGLSSLTPVSPTASMPPAFPRLELPELLEPPALP 288
                 QS        +E   G   L + L       P +S+PP   RL+ P  L P A P
Sbjct: 1203 LTPESQSKT------SETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEP--LVPVAAP 1254

Query: 289  SPLRPP-----APPLPPPPVLSTVANPQSCHS 315
             P   P      PP PPP   S+ + P    S
Sbjct: 1255 MPQSGPQPNLETPPQPPPRSRSSHSLPSEASS 1286


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 63/258 (24%), Positives = 89/258 (34%), Gaps = 26/258 (10%)

Query: 77   AAAGPRTPSAHIPVPAQRATPGKARLDEVMAAAALTSLSTSPLLLGAPVAAFSPEPGLEP 136
            +A  P    A +  PA  A+   A     MAA     L+ SP    AP+   +P PG  P
Sbjct: 1561 SAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAP 1620

Query: 137  WKEALVRPPGSYSSSSNSGDWGWDLASDQSSPSTPSPPLPPEAAHFLFGEPTLRKRKSPA 196
               +   P    + SS  G     LAS    P+ P+P L P +   +   P      SPA
Sbjct: 1621 VLASSQTPVPVMAPSSTPGT---SLASASPVPA-PTPVLAPSSTQTMLPAPVPSPLPSPA 1676

Query: 197  QVMFQCLWKSCGKVLSTASAMQRHIRLVHLGRQAEPEQSDGEEDFYYTELDVGVDTLTDG 256
                  L  +    L  +S  Q     + LG    P+     +    T     V T    
Sbjct: 1677 STQTLALAPALAPTLGGSSPSQ----TLSLG-TGNPQGPFPTQTLSLTPASSLVPTPAQT 1731

Query: 257  LSSL--TPVSPTASMPPAFPRLELPELLEPPALPSPLRPPAPPLPPPPVLSTVANPQSCH 314
            LS     P+ PT ++  A               P+P   PA P+ P P  +    P S  
Sbjct: 1732 LSLAPGPPLGPTQTLSLA---------------PAPPLAPASPVGPAPAHTLTLAPASSS 1776

Query: 315  SDRVYQGCLTPARLEPQP 332
            +  +    +    L P P
Sbjct: 1777 ASLLAPASVQTLTLSPAP 1794



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 16/58 (27%), Positives = 25/58 (43%), Gaps = 2/58 (3%)

Query: 257  LSSLTPVS--PTASMPPAFPRLELPELLEPPALPSPLRPPAPPLPPPPVLSTVANPQS 312
            +S+  P++  P   +P   P  ++P    P   P P   P P   PPP  + +  P S
Sbjct: 2468 ISAPNPITILPVHILPSPPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSS 2525



 Score = 30.4 bits (67), Expect = 2.8
 Identities = 31/121 (25%), Positives = 48/121 (39%), Gaps = 10/121 (8%)

Query: 20   APWLRAEGPGPRAAPVTVPTPPQGSSVGGGFAGLEFARPQES------EPRASDLGAPRT 73
            +P+  A  P P  A +  P      ++    A +  A PQ +       P  + L     
Sbjct: 1557 SPFPSAPNPAPAQASLLAPASSASQALATPLAPM--AAPQTAILAPSPAPPLAPLPVLAP 1614

Query: 74   WTGAAAGPRTPSAHIPVPAQRATPGK--ARLDEVMAAAALTSLSTSPLLLGAPVAAFSPE 131
              GAA    +    +PV A  +TPG   A    V A   + + S++  +L APV +  P 
Sbjct: 1615 SPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPS 1674

Query: 132  P 132
            P
Sbjct: 1675 P 1675



 Score = 30.0 bits (66), Expect = 3.7
 Identities = 33/120 (27%), Positives = 44/120 (36%), Gaps = 27/120 (22%)

Query: 262  PVSPTASMPPAFPRLE-------LPELLE-----------PPALPSPLRPPAPPLPPPPV 303
            P+ P    PP  P L        +P++L            PP +P+  RPP P L PP  
Sbjct: 1018 PLGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPAS-RPPGPVLLPPLQ 1076

Query: 304  LSTVANPQSCHSD-RVYQGCLTPAR-------LEPQPTEVGACPPALSSRIGVTLRKPRG 355
             ++ + PQ   S   V  G   P           P P  +   PP  SS +   L  P G
Sbjct: 1077 PNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPG 1136



 Score = 30.0 bits (66), Expect = 3.7
 Identities = 23/62 (37%), Positives = 28/62 (45%), Gaps = 12/62 (19%)

Query: 260  LTPVSPTASMPPAFPRLELPELLEPPALPSPLRPPAP-------PLPPP----PVLSTVA 308
            LTPV P A  P   P   LP +L P    +P R P P       P+P P    P+L  V 
Sbjct: 1321 LTPVPPLAPAPRP-PSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVH 1379

Query: 309  NP 310
            +P
Sbjct: 1380 SP 1381



 Score = 29.3 bits (64), Expect = 6.3
 Identities = 47/176 (26%), Positives = 57/176 (32%), Gaps = 28/176 (15%)

Query: 27   GPGPRAAPVTVPTPPQ----------------GSSVGGGFAGLEFARPQESEPRASDLGA 70
            GP   A   ++PTPPQ                GS   G  A L    P     R      
Sbjct: 2807 GPCEAAPSSSLPTPPQQPFIARRHIELGVTGGGSPENGDGALLAITPPAVKRRRGRPPKK 2866

Query: 71   PRTWTGAAAG-PRTPSAHIPVPAQRATPGKARLDEVMAAAALT-SLSTSPLLLGAPVAAF 128
             R+   A  G    PS+ +      A P       ++A   L   L   P  LG P    
Sbjct: 2867 NRSPADAGRGVDEAPSSTLKGKTNGADPVPGPETLIVADPVLEPQLIPGPQPLG-PQPVH 2925

Query: 129  SPEPGLEPW-KEALVRPP--------GSYSSSSNSGDWGWDLASDQSSPSTPSPPL 175
             P P L P  K    RPP        G+ SS+ +             SP TP PPL
Sbjct: 2926 RPNPLLSPVEKRRRGRPPKARDLPIPGTISSAGDGNSESRTQPPPHPSPLTPLPPL 2981


>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
          Length = 1682

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 90/364 (24%), Positives = 126/364 (34%), Gaps = 44/364 (12%)

Query: 4   PPPRAAGRD--PSALRAEAPWLRAEGPGPRAAPVTVPTPPQGSSVGGGFAGLEFARPQES 61
           PP R   R   P      AP   A  PG R  P   P P            L   RP  S
Sbjct: 299 PPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGS 358

Query: 62  EPRASDLGAPRTWTGAAAGPRTPSAHIPVPAQR--ATPGKARLDEVMAAA--ALTSLSTS 117
           + R S +   R+   ++  P   +A +P    R    PG        +++   L  +  +
Sbjct: 359 DLRESRV--QRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPN 416

Query: 118 PLLLGAPVAAFSPEPGLEPWKEALVRPPGSYSSSSNSGDWGWDLASDQSS----PSTPSP 173
           P   G P A     P LE      + P    + SS     G   A+   S    PS+P P
Sbjct: 417 P---GIPGADHYQTPALEVSHHGRLGPS---AHSSRKPFLGAPAATPHLSLPPGPSSPPP 470

Query: 174 P------LPPEAAHFLFGEPTLRKRKSPAQVMFQCLWKSCGKVLSTASAMQRHIRLVHLG 227
           P       PP    +L G P  R  +   +++ +  + + G        +    R   LG
Sbjct: 471 PPCPRLLRPPPPPAWLKG-PACRAAREDGEILEELFFGTEGPPRPAPPPLPH--REGFLG 527

Query: 228 RQAEPEQSDGEEDFYYTELDVGVDTLTD----GLSSLTPVSPTASMPPAFPRLELPELLE 283
             A    S G +D +         T +     G  S +P  P +  PP +    +  L  
Sbjct: 528 PPAS-RFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPR 586

Query: 284 PPALPSPLRPPA-PPLPPPPVLSTVANPQSCHSDRVYQGCL------TPARLEPQPTEVG 336
           PP   SP + P  PPL P  +    A P SCH +    G         P    P+  EVG
Sbjct: 587 PP---SPAQNPQDPPLVPLTLALPPAPPSSCHQNT--SGSFRRPESPRPRVSFPKTPEVG 641

Query: 337 ACPP 340
             PP
Sbjct: 642 PGPP 645



 Score = 37.0 bits (84), Expect = 0.030
 Identities = 19/47 (40%), Positives = 22/47 (46%), Gaps = 9/47 (19%)

Query: 264 SPTASMPPAFPRLELPELLEPPALPSPLRPPAPPLPPPPVLSTVANP 310
           S    +PP  P       L PP LP P  PP PP PPPP+     +P
Sbjct: 235 SEQTGLPPGLP-------LPPPPLPPP--PPPPPPPPPPLPGLATSP 272



 Score = 32.3 bits (72), Expect = 0.74
 Identities = 32/107 (29%), Positives = 41/107 (38%), Gaps = 24/107 (22%)

Query: 256 GLSSLTPVSPTASMPPAFPRLELPELLEPPALPSPLRPPAPPLP----PPPVLSTVANPQ 311
           G S+ +   P    P A P L LP        P P  PP PP P    PPP  + +  P 
Sbjct: 439 GPSAHSSRKPFLGAPAATPHLSLP--------PGPSSPPPPPCPRLLRPPPPPAWLKGP- 489

Query: 312 SCHSDR--------VYQGCLTPARLEPQP---TEVGACPPALSSRIG 347
           +C + R        ++ G   P R  P P    E    PPA    +G
Sbjct: 490 ACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVG 536



 Score = 32.3 bits (72), Expect = 0.74
 Identities = 98/443 (22%), Positives = 146/443 (32%), Gaps = 87/443 (19%)

Query: 4   PPPRAAGRDPSALRAEAPWLRAEGP-GPRAAPVTVPTPPQGSSVGGGFAGLEFARPQESE 62
           PPP  A       R  +P   A+ P  P   P+T+  PP   S         F RP+   
Sbjct: 573 PPPYLARSIDPLPRPPSP---AQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPR 629

Query: 63  PRASDLGAPRTWTGAAAGPRTPS--------AHIPVPAQR-----ATPGKARLDEVMAAA 109
           PR S    P    G   GP + +          +P    R      TP + + +E     
Sbjct: 630 PRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFK 689

Query: 110 AL-TSLSTSPLLLGAPV----------AAFSPEPGLEPWKEALVRPPGSYSSSSNSG--- 155
            L   L+    +L   +          A  +P+P L+    +L  P  + ++ + +    
Sbjct: 690 ILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAV 749

Query: 156 ------DWGWDLASDQSSPSTPSPPLPPEAAHFLFGEPTLRKRKSPAQVMFQCLWKSCGK 209
                        + Q     P P LPP      F  P+  +   P       L KS   
Sbjct: 750 AVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLAS 809

Query: 210 VLSTASAMQRHIRLVHLGRQAEPEQSDGEEDFYYTELDVGVDTLTDGLSSLTPVS----- 264
           VL       R       G  A      G      T+   G  +   G ++L P S     
Sbjct: 810 VLEGQKYCYR-------GTGAAVSTRPG--PLPTTQYSPGPPS---GATALPPTSAAPSA 857

Query: 265 -----PTASMPPAFPRLELPELLEPPA----LPSPLRP--PAPPLPPPP------VLSTV 307
                P+AS    F     P   E  A    +P P+ P  P PPL  PP      VL  +
Sbjct: 858 QGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEI 917

Query: 308 ANPQSCHSDRVYQGCLTPARLEP----QPTEVGA---CPPALSSRIGVTLRKPRGDAKKC 360
           +       +RV +    PA  +P    +P + G     PPA +      +    G  K+ 
Sbjct: 918 SRACETLVERVGRSATDPA--DPVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKRR 975

Query: 361 RKVYGMERRDLWCTACRWKKACQ 383
           +K +  E R       R ++AC+
Sbjct: 976 QKEHQKEHR-------RHRRACK 991


>gi|60460889 Myb protein P42POP [Homo sapiens]
          Length = 399

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 77/330 (23%), Positives = 109/330 (33%), Gaps = 95/330 (28%)

Query: 20  APWLRAEGPGPRAAPVTVPTPPQGSSVGGGFA--GLEFARPQESEPRASDLGAPRTWTGA 77
           AP   A    P AAP + P PP         +    E  R   S    +   +P  W   
Sbjct: 126 APGAGAGAEEPPAAPSSQPPPPSACPQRYVLSEDRREDRRADTSAHSKAGSSSPEPWARP 185

Query: 78  AAGPRTPSAHIPVPAQRATPGKARLDEVMAAAALTSLSTSPLLLGAPVAAFSPEPGLEPW 137
           +  P+      P P +R +P  + L  V                  P  A SP P   P 
Sbjct: 186 SCTPQ--EGGCPRPKERESPPPSALQPVQ----------------LPRLALSPPPPAPP- 226

Query: 138 KEALVRPPGSYSSSSNSGDWGWDLASDQSSPSTPSPPLPPEAAHFLFGEPTLRKRKSPAQ 197
               + PP   +               Q +PS PSPP PP         PTL     P+ 
Sbjct: 227 ----LPPPPPLA---------------QVAPSPPSPPPPPRP------PPTL-SASDPSL 260

Query: 198 VMFQCLWKSCGKVLSTASAMQRHIRLVHLGRQAEPEQSDGEEDFYYTELDVGVDTLTDGL 257
              +   ++   +   A  +++                             G+  L++ L
Sbjct: 261 DFLRAQQETANAIRELAGTLRQ-----------------------------GLAKLSEAL 291

Query: 258 SSLTPV---SPTASMPPAFPRLELPELLEPPALPSPLRPPAPPLPPP-PVLSTVANPQSC 313
           S+L P+   +P  S+PP  P         PP  P P  PP P LPPP P +     P S 
Sbjct: 292 SALLPLLPGTPVDSLPPPLP---------PPPPPPP--PPRPVLPPPAPKVEITPEPVSV 340

Query: 314 HSDRVYQGCLTPAR---LEPQPTEVGACPP 340
            +  V  G +  AR   + P+  E    PP
Sbjct: 341 VA-AVVDGAVVAARGVIIAPRSEEGAPRPP 369



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 38/108 (35%), Positives = 47/108 (43%), Gaps = 29/108 (26%)

Query: 265 PTASMPPAFPRLELPELLEPPALPSPLRPPAPPLPPPPVLSTVA-NPQSCHSDRVYQGCL 323
           P+A  P   PRL L     PP       PPAPPLPPPP L+ VA +P S           
Sbjct: 205 PSALQPVQLPRLAL----SPP-------PPAPPLPPPPPLAQVAPSPPS----------- 242

Query: 324 TPARLEPQPTEVGACPPALSSRIGVTLRKPRGDAKKCRKVYGMERRDL 371
            P    P PT + A  P+L       LR  +  A   R++ G  R+ L
Sbjct: 243 PPPPPRPPPT-LSASDPSLD-----FLRAQQETANAIRELAGTLRQGL 284


>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
          Length = 1612

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 51/177 (28%), Positives = 68/177 (38%), Gaps = 34/177 (19%)

Query: 2    ERPPPRAAGRDPSALRAEAPWLRAEGPGPRAAPVTVPTP-----------------PQGS 44
            +RPPP +  R P+  R E   + A  P P  A   +  P                 PQ  
Sbjct: 1163 QRPPPPSGARSPAPTRKEFGGIGAP-PSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAG 1221

Query: 45   SVGGGFAGLEFARPQESEPRASDLGAPRTWTGAAAGPRTPSAHIPVPAQRATPGKARLDE 104
              G G AG   ARP    PRA  + AP++   A+AG  TP +         + G   L E
Sbjct: 1222 LAGPGPAGYSTARP-TIPPRAGVISAPQSHARASAGRLTPESQ--SKTSETSKGSTFLPE 1278

Query: 105  VMAAAALTSLSTS----------PLLLGAPVAAFSPEPGLEPWKEALVRPPGSYSSS 151
             +   A     +S          PL+   PVAA  P+ G +P  E   +PP    SS
Sbjct: 1279 PLKPQAAFPPQSSLPPPAQRLQEPLV---PVAAPMPQSGPQPNLETPPQPPPRSRSS 1332



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 71/291 (24%), Positives = 90/291 (30%), Gaps = 61/291 (20%)

Query: 30   PRAAPVTVPTPPQGSSVGGGFAGLEFARPQESEPRASDLGAPRTWTGAAAGPRTPSAHIP 89
            P  AP   P PP   S        + A P   +  A  L   R        P T     P
Sbjct: 1107 PSRAPSRTPGPPSAQSSP---IDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTR----P 1159

Query: 90   VPAQRATPGKARLDEVMAAAALTSLSTSPLLLGAPVAAFSPEPGLEPWKEALVRPPGSYS 149
             P QR  P                +       GAP     P PG+   +    + PG+ +
Sbjct: 1160 APPQRPPPPSGARSPAPTRKEFGGI-------GAP-----PSPGVARREMEAPKSPGT-T 1206

Query: 150  SSSNSGDWGWDLASDQSSPSTPSPPLPPEAAHFLFGEPTLRKRKSPAQVMFQCLWKSCGK 209
               N G         +S PS  +    P  A +    PT+  R                 
Sbjct: 1207 RKDNIG---------RSQPSPQAGLAGPGPAGYSTARPTIPPRAG--------------- 1242

Query: 210  VLSTASAMQRHIRLVHLGRQAEPEQSDGEEDFYYTELDVGVDTLTDGLSSLTPVSPTASM 269
                 SA Q H R    GR     QS        +E   G   L + L       P +S+
Sbjct: 1243 ---VISAPQSHAR-ASAGRLTPESQSKT------SETSKGSTFLPEPLKPQAAFPPQSSL 1292

Query: 270  PPAFPRLELPELLEPPALPSPLRPP-----APPLPPPPVLSTVANPQSCHS 315
            PP   RL+ P  L P A P P   P      PP PPP   S+ + P    S
Sbjct: 1293 PPPAQRLQEP--LVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASS 1341


>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
          Length = 1350

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 51/177 (28%), Positives = 68/177 (38%), Gaps = 34/177 (19%)

Query: 2    ERPPPRAAGRDPSALRAEAPWLRAEGPGPRAAPVTVPTP-----------------PQGS 44
            +RPPP +  R P+  R E   + A  P P  A   +  P                 PQ  
Sbjct: 1163 QRPPPPSGARSPAPTRKEFGGIGAP-PSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAG 1221

Query: 45   SVGGGFAGLEFARPQESEPRASDLGAPRTWTGAAAGPRTPSAHIPVPAQRATPGKARLDE 104
              G G AG   ARP    PRA  + AP++   A+AG  TP +         + G   L E
Sbjct: 1222 LAGPGPAGYSTARP-TIPPRAGVISAPQSHARASAGRLTPESQ--SKTSETSKGSTFLPE 1278

Query: 105  VMAAAALTSLSTS----------PLLLGAPVAAFSPEPGLEPWKEALVRPPGSYSSS 151
             +   A     +S          PL+   PVAA  P+ G +P  E   +PP    SS
Sbjct: 1279 PLKPQAAFPPQSSLPPPAQRLQEPLV---PVAAPMPQSGPQPNLETPPQPPPRSRSS 1332



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 71/291 (24%), Positives = 90/291 (30%), Gaps = 61/291 (20%)

Query: 30   PRAAPVTVPTPPQGSSVGGGFAGLEFARPQESEPRASDLGAPRTWTGAAAGPRTPSAHIP 89
            P  AP   P PP   S        + A P   +  A  L   R        P T     P
Sbjct: 1107 PSRAPSRTPGPPSAQSSP---IDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPTR----P 1159

Query: 90   VPAQRATPGKARLDEVMAAAALTSLSTSPLLLGAPVAAFSPEPGLEPWKEALVRPPGSYS 149
             P QR  P                +       GAP     P PG+   +    + PG+ +
Sbjct: 1160 APPQRPPPPSGARSPAPTRKEFGGI-------GAP-----PSPGVARREMEAPKSPGT-T 1206

Query: 150  SSSNSGDWGWDLASDQSSPSTPSPPLPPEAAHFLFGEPTLRKRKSPAQVMFQCLWKSCGK 209
               N G         +S PS  +    P  A +    PT+  R                 
Sbjct: 1207 RKDNIG---------RSQPSPQAGLAGPGPAGYSTARPTIPPRAG--------------- 1242

Query: 210  VLSTASAMQRHIRLVHLGRQAEPEQSDGEEDFYYTELDVGVDTLTDGLSSLTPVSPTASM 269
                 SA Q H R    GR     QS        +E   G   L + L       P +S+
Sbjct: 1243 ---VISAPQSHAR-ASAGRLTPESQSKT------SETSKGSTFLPEPLKPQAAFPPQSSL 1292

Query: 270  PPAFPRLELPELLEPPALPSPLRPP-----APPLPPPPVLSTVANPQSCHS 315
            PP   RL+ P  L P A P P   P      PP PPP   S+ + P    S
Sbjct: 1293 PPPAQRLQEP--LVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASS 1341


>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 673

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 98/372 (26%), Positives = 124/372 (33%), Gaps = 52/372 (13%)

Query: 1   MERPPPRAA-GRDPSALRAEAPWLRAEGPGPRAAPVTVPT--PPQGSSVGGGFAGLEF-A 56
           + R PPRA+  R PS  RA        G    A+P   P+   P GS       GL   A
Sbjct: 331 ISRTPPRASITRTPS--RASPT-----GKPSTASPTGTPSRASPTGSPSTASLTGLSSTA 383

Query: 57  RPQESEPRASDLGAPRTWTGAAAGPRTPSAHIPVPAQRATPGKARLDEVMAAAALTSLST 116
            P  + PRAS  G P T    A+  R P    P      T    ++D   A+   T    
Sbjct: 384 SPTGTPPRASPTGTPST----ASLTRKPPRASPTGMLSRT-SITKMDST-ASPTRTPPRA 437

Query: 117 SPLLLGAPVAAFSPEPGLEPWKEALVRPPGSYSSSSNSGDWGWDLASDQSSPSTPSPPLP 176
           SP   G P  A    P   P + +   P G+ S++S +G      AS   SPST SP   
Sbjct: 438 SP--TGTPPRA---SPTGTPSRAS---PTGTQSTASPTG--SPSTASPTGSPSTASPTGS 487

Query: 177 PEAAHFLF--GEPTLRKRKSPAQVMFQCLWKSCGKVLSTASAMQRHIRLVHLGRQAEPEQ 234
           P  A         +L K +S A +       S     STAS        + +G  +    
Sbjct: 488 PSRASLTRTPSRASLTKMESTASITRTPSRASPTWTPSTASPTGSPSTALAMGSPSRAAL 547

Query: 235 SDGEEDFYYTELDVGVDTLTDGLSSLTPVSPT---ASMPPAFPRLELPELLEPPALPSP- 290
           +        T         T   +SLT    T     MPP+     +P    P  +PS  
Sbjct: 548 TRTPSRASLTRTPSRASLTTPSRASLTRTPSTVLLTRMPPSASPTGMPSRTSPTGMPSSA 607

Query: 291 -------------LRPPAPPLPPPPVLSTVANPQSCHSDRVYQGCLTPARLEPQPTEVGA 337
                          P A P   PP  S    P             TP R  P  T   A
Sbjct: 608 LLTKMDSTASITRTPPRASPTETPPRASPTGTPPRASPTG------TPPRASPTGTPPRA 661

Query: 338 CPPALSSRIGVT 349
            P    SR   T
Sbjct: 662 SPTGTPSRASPT 673


>gi|20986497 mitogen-activated protein kinase 7 isoform 1 [Homo
           sapiens]
          Length = 816

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 48/163 (29%), Positives = 65/163 (39%), Gaps = 13/163 (7%)

Query: 17  RAEAPWLRAEGPGPRAAPVTVPTPPQGSSVGGGFAGLEFARPQESEPRASDLGAPRTWTG 76
           R  AP L +  P P  AP   PTP Q +S   G      A+P   +P+++      + +G
Sbjct: 577 RPAAPALTSV-PAPAPAPTPTPTPVQPTSPPPG----PVAQPTGPQPQSAG-----STSG 626

Query: 77  AAAGPRTPSAHIPVPAQRATPGKARLDEVMAAAALTSLSTSPLLLGAPVAAFSPEPGLEP 136
               P  P    P P     PG   +      A  TSL  +  L+  P    S  PG+ P
Sbjct: 627 PVPQPACPPPG-PAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSSTPGVLP 685

Query: 137 WKEALVRPP--GSYSSSSNSGDWGWDLASDQSSPSTPSPPLPP 177
           +    + PP  G    SS S     +L + Q S S    PLPP
Sbjct: 686 YFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPP 728



 Score = 29.3 bits (64), Expect = 6.3
 Identities = 33/115 (28%), Positives = 42/115 (36%), Gaps = 25/115 (21%)

Query: 261 TPVSPTASMP-----PAFPR----------LELPELLEPPALPSPLRPPAP-PLPPPPVL 304
           TPV PT+  P     P  P+          +  P    P   P P  PP P P+P PP +
Sbjct: 598 TPVQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQI 657

Query: 305 STVAN---PQSCHSDRVYQGCLTPARLE------PQPTEVGACPPALSSRIGVTL 350
           +T  +    QS        G  TP  L       P P   GA   ++S    V L
Sbjct: 658 ATSTSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNL 712


>gi|209529736 mitogen-activated protein kinase 7 isoform 1 [Homo
           sapiens]
          Length = 816

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 48/163 (29%), Positives = 65/163 (39%), Gaps = 13/163 (7%)

Query: 17  RAEAPWLRAEGPGPRAAPVTVPTPPQGSSVGGGFAGLEFARPQESEPRASDLGAPRTWTG 76
           R  AP L +  P P  AP   PTP Q +S   G      A+P   +P+++      + +G
Sbjct: 577 RPAAPALTSV-PAPAPAPTPTPTPVQPTSPPPG----PVAQPTGPQPQSAG-----STSG 626

Query: 77  AAAGPRTPSAHIPVPAQRATPGKARLDEVMAAAALTSLSTSPLLLGAPVAAFSPEPGLEP 136
               P  P    P P     PG   +      A  TSL  +  L+  P    S  PG+ P
Sbjct: 627 PVPQPACPPPG-PAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSSTPGVLP 685

Query: 137 WKEALVRPP--GSYSSSSNSGDWGWDLASDQSSPSTPSPPLPP 177
           +    + PP  G    SS S     +L + Q S S    PLPP
Sbjct: 686 YFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPP 728



 Score = 29.3 bits (64), Expect = 6.3
 Identities = 33/115 (28%), Positives = 42/115 (36%), Gaps = 25/115 (21%)

Query: 261 TPVSPTASMP-----PAFPR----------LELPELLEPPALPSPLRPPAP-PLPPPPVL 304
           TPV PT+  P     P  P+          +  P    P   P P  PP P P+P PP +
Sbjct: 598 TPVQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQI 657

Query: 305 STVAN---PQSCHSDRVYQGCLTPARLE------PQPTEVGACPPALSSRIGVTL 350
           +T  +    QS        G  TP  L       P P   GA   ++S    V L
Sbjct: 658 ATSTSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNL 712


>gi|209529734 mitogen-activated protein kinase 7 isoform 1 [Homo
           sapiens]
          Length = 816

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 48/163 (29%), Positives = 65/163 (39%), Gaps = 13/163 (7%)

Query: 17  RAEAPWLRAEGPGPRAAPVTVPTPPQGSSVGGGFAGLEFARPQESEPRASDLGAPRTWTG 76
           R  AP L +  P P  AP   PTP Q +S   G      A+P   +P+++      + +G
Sbjct: 577 RPAAPALTSV-PAPAPAPTPTPTPVQPTSPPPG----PVAQPTGPQPQSAG-----STSG 626

Query: 77  AAAGPRTPSAHIPVPAQRATPGKARLDEVMAAAALTSLSTSPLLLGAPVAAFSPEPGLEP 136
               P  P    P P     PG   +      A  TSL  +  L+  P    S  PG+ P
Sbjct: 627 PVPQPACPPPG-PAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSSTPGVLP 685

Query: 137 WKEALVRPP--GSYSSSSNSGDWGWDLASDQSSPSTPSPPLPP 177
           +    + PP  G    SS S     +L + Q S S    PLPP
Sbjct: 686 YFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPP 728



 Score = 29.3 bits (64), Expect = 6.3
 Identities = 33/115 (28%), Positives = 42/115 (36%), Gaps = 25/115 (21%)

Query: 261 TPVSPTASMP-----PAFPR----------LELPELLEPPALPSPLRPPAP-PLPPPPVL 304
           TPV PT+  P     P  P+          +  P    P   P P  PP P P+P PP +
Sbjct: 598 TPVQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQI 657

Query: 305 STVAN---PQSCHSDRVYQGCLTPARLE------PQPTEVGACPPALSSRIGVTL 350
           +T  +    QS        G  TP  L       P P   GA   ++S    V L
Sbjct: 658 ATSTSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNL 712


>gi|20986499 mitogen-activated protein kinase 7 isoform 2 [Homo
           sapiens]
          Length = 677

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 48/163 (29%), Positives = 65/163 (39%), Gaps = 13/163 (7%)

Query: 17  RAEAPWLRAEGPGPRAAPVTVPTPPQGSSVGGGFAGLEFARPQESEPRASDLGAPRTWTG 76
           R  AP L +  P P  AP   PTP Q +S   G      A+P   +P+++      + +G
Sbjct: 438 RPAAPALTSV-PAPAPAPTPTPTPVQPTSPPPG----PVAQPTGPQPQSAG-----STSG 487

Query: 77  AAAGPRTPSAHIPVPAQRATPGKARLDEVMAAAALTSLSTSPLLLGAPVAAFSPEPGLEP 136
               P  P    P P     PG   +      A  TSL  +  L+  P    S  PG+ P
Sbjct: 488 PVPQPACPPPG-PAPHPTGPPGPIPVPAPPQIATSTSLLAAQSLVPPPGLPGSSTPGVLP 546

Query: 137 WKEALVRPP--GSYSSSSNSGDWGWDLASDQSSPSTPSPPLPP 177
           +    + PP  G    SS S     +L + Q S S    PLPP
Sbjct: 547 YFPPGLPPPDAGGAPQSSMSESPDVNLVTQQLSKSQVEDPLPP 589



 Score = 29.3 bits (64), Expect = 6.3
 Identities = 33/115 (28%), Positives = 42/115 (36%), Gaps = 25/115 (21%)

Query: 261 TPVSPTASMP-----PAFPR----------LELPELLEPPALPSPLRPPAP-PLPPPPVL 304
           TPV PT+  P     P  P+          +  P    P   P P  PP P P+P PP +
Sbjct: 459 TPVQPTSPPPGPVAQPTGPQPQSAGSTSGPVPQPACPPPGPAPHPTGPPGPIPVPAPPQI 518

Query: 305 STVAN---PQSCHSDRVYQGCLTPARLE------PQPTEVGACPPALSSRIGVTL 350
           +T  +    QS        G  TP  L       P P   GA   ++S    V L
Sbjct: 519 ATSTSLLAAQSLVPPPGLPGSSTPGVLPYFPPGLPPPDAGGAPQSSMSESPDVNL 573


>gi|40807452 peroxisome proliferator-activated receptor gamma,
            coactivator-related 1 [Homo sapiens]
          Length = 1664

 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 50/181 (27%), Positives = 65/181 (35%), Gaps = 11/181 (6%)

Query: 19   EAPWLRAEGPGPRAAPVTVPTPPQGSSVGGGFAGLEFARPQESEPRASDLGAPRTWTGAA 78
            E P L    P  ++    VPTPP  S+     AG     P    P       P +     
Sbjct: 851  EMPLLARPSPPVQSVSPAVPTPPSMSAALPFPAGGLGMPPSLPPPPLQPPSLPLSMGPVL 910

Query: 79   AGPRTPSAHIPVPAQRATPGKARLDEVMAAAALTSLSTSPLLLGAPVAAFSPEPGLEPWK 138
              P T  A  P+P+    P  +          L    T PL+ G P A   P     PW 
Sbjct: 911  PDPFTHYA--PLPSWPCYPHVSP----SGYPCLPPPPTVPLVSGTPGAYAVPPTCSVPWA 964

Query: 139  EALVRPPGSYSSSSNSGDWGWDLASDQSSP---STPSPPLPPEAAHFLFGEPTLRKRKSP 195
                 P   YSS+   G  GW     Q +P   + P PPLPP +      +P +  R +P
Sbjct: 965  PPPA-PVSPYSSTCTYGPLGWG-PGPQHAPFWSTVPPPPLPPASIGRAVPQPKMESRGTP 1022

Query: 196  A 196
            A
Sbjct: 1023 A 1023



 Score = 32.0 bits (71), Expect = 0.97
 Identities = 19/44 (43%), Positives = 25/44 (56%), Gaps = 4/44 (9%)

Query: 261 TPVSPTASMPPAFPRLELPELLEPPALPSPLRPPAPPLPPPPVL 304
           TP S +A++P     L +P  L PP    PL+PP+ PL   PVL
Sbjct: 871 TPPSMSAALPFPAGGLGMPPSLPPP----PLQPPSLPLSMGPVL 910



 Score = 30.4 bits (67), Expect = 2.8
 Identities = 28/99 (28%), Positives = 36/99 (36%), Gaps = 9/99 (9%)

Query: 260 LTPVSPTASMPPAFPRLELPELLEPPALPSPLRPPAPPLPPPPVLS---TVANPQSCHSD 316
           L PV P+ + P   P +  P    P         P    P PPV S    V  P S  + 
Sbjct: 819 LVPVGPSPASPSPEPPVSKPVASSPTEQVPSQEMPLLARPSPPVQSVSPAVPTPPSMSAA 878

Query: 317 RVYQ--GCLTPARLEPQPTEVGACPPALSSRIGVTLRKP 353
             +   G   P  L P P +    PP+L   +G  L  P
Sbjct: 879 LPFPAGGLGMPPSLPPPPLQ----PPSLPLSMGPVLPDP 913


>gi|111118994 brain-specific angiogenesis inhibitor 1 precursor [Homo
            sapiens]
          Length = 1584

 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 48/146 (32%), Positives = 56/146 (38%), Gaps = 12/146 (8%)

Query: 167  SPSTPSPPLPPEAAHFLFGEPTLRKRKSPAQ--VMFQCLWKSCGKVLSTASAMQRHIRLV 224
            SP  P  PLP    H L    TL++ K+P    V    ++K     LS A         V
Sbjct: 1291 SPRYPGGPLPDFPNHSL----TLKRDKAPKSSFVGDGDIFKKLDSELSRAQEKALDTSYV 1346

Query: 225  HLGRQ-AEPEQSDGEEDFYYTELDVGVDTLTDGLS-----SLTPVSPTASMPPAFPRLEL 278
             L    A       EE  Y   +D    T    LS     SL   SP +  PP+    E 
Sbjct: 1347 ILPTATATLRPKPKEEPKYSIHIDQMPQTRLIHLSTAPEASLPARSPPSRQPPSGGPPEA 1406

Query: 279  PELLEPPALPSPLRPPAPPLPPPPVL 304
            P    PP  P P  PP  PLPPPP L
Sbjct: 1407 PPAQPPPPPPPPPPPPQQPLPPPPNL 1432


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 35/113 (30%), Positives = 45/113 (39%), Gaps = 16/113 (14%)

Query: 261 TPVSPTASMPPAFPR---LELPELLEPP-----------ALPSPLRPPAPPLPPPPVLST 306
           TP  P   +PP  P    ++ P L+ PP           A P P  PP PP PPPP    
Sbjct: 178 TPPPPPPPLPPPLPSSSPIKTP-LVSPPGPLTKGNLPVVAPPVPCAPPPPP-PPPPPTPP 235

Query: 307 VANPQSCHSDRVYQGCLTPARLEPQPTEVGACPPALSSRIGVTLRKPRGDAKK 359
              P S  SD+  +  L P  L P P  +   PP     +      P  DA++
Sbjct: 236 PLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQE 288



 Score = 32.0 bits (71), Expect = 0.97
 Identities = 14/21 (66%), Positives = 14/21 (66%), Gaps = 2/21 (9%)

Query: 284 PPALPSPLRPPAPPL--PPPP 302
           PP  P PL PP PPL  PPPP
Sbjct: 4   PPPPPPPLPPPPPPLGAPPPP 24



 Score = 32.0 bits (71), Expect = 0.97
 Identities = 19/49 (38%), Positives = 22/49 (44%), Gaps = 11/49 (22%)

Query: 269 MPPAFPRL-----------ELPELLEPPALPSPLRPPAPPLPPPPVLST 306
           +PPA PRL             P     PA P P  PP PP  PPP+ S+
Sbjct: 145 IPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSS 193



 Score = 30.8 bits (68), Expect = 2.2
 Identities = 72/298 (24%), Positives = 87/298 (29%), Gaps = 98/298 (32%)

Query: 39  TPPQ-GSSVGGGFAGLEFARPQESEPRASDLGAPRTWTGAAAGPRTPSAHIP---VPAQR 94
           TPP  G    GGF  L   RP      A         TG   G R PS  +P   +    
Sbjct: 94  TPPTLGDLFAGGFPVL---RPAGQRDVAGGK------TGQGPGSRAPSPRLPNKTISGPL 144

Query: 95  ATPGKARLDEVMAA--AALTSLSTSPLLLGAPVAAFSPEPGL-------EPWKEALVRPP 145
             P   RL     A  AA T+     +    P     P P L        P K  LV PP
Sbjct: 145 IPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPP 204

Query: 146 GSYSSSSNSGDWGWDLASDQSSPSTPSPPLPPEAAHFLFGEPTLRKRKSPAQVMFQCLWK 205
           G  +  +               P  P PP PP         P       PA V+      
Sbjct: 205 GPLTKGNLP-------VVAPPVPCAPPPPPPPP--------PPTPPPLPPASVL------ 243

Query: 206 SCGKVLSTASAMQRHIRLVHLGRQAEPEQSDGEEDFYYTELDVGVDTLTDGLSSLTPVSP 265
                  +  A++  +  +HL     P                             P+ P
Sbjct: 244 -------SDKAVKPQLAPLHLPPIPPP----------------------------LPLLP 268

Query: 266 TASMP--PAFPRLELPELLEPPALPSPLRP----------PAPPLP--------PPPV 303
               P   A P     +  EPPA P PL P          PAPPLP        PPP+
Sbjct: 269 PCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPL 326



 Score = 29.6 bits (65), Expect = 4.8
 Identities = 19/48 (39%), Positives = 21/48 (43%), Gaps = 5/48 (10%)

Query: 260 LTPVSPTASMPPAFPRLELPELLEPPALPSP--LRPPAPPLPPPPVLS 305
           L P+ P     P  P    P L   PA P+     PPAPP P PP  S
Sbjct: 257 LPPIPPPL---PLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYAS 301


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 77/314 (24%), Positives = 112/314 (35%), Gaps = 58/314 (18%)

Query: 30   PRAAPVTVPTPPQGSSVGGGFAGLEFARPQESEPRASDLGAPRTWTGAAAG------PRT 83
            P +    VPTP + +S            P+E    A+ +  P   T  AA       P +
Sbjct: 1039 PTSPAAAVPTPEEPTSPAAAVP-----TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1093

Query: 84   PSAHIPVPAQRATPGKA--RLDEVMAAAALTSLSTSPLLLGAPVAAFSPEPGLEPWKEAL 141
            P+A +P P +  +P  A    +E  + AA       P    A  AA  P P    +    
Sbjct: 1094 PAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEP----ASPAAAVPTPEEPAFPAPA 1149

Query: 142  VRPPGSYSSSSNSGDWGWDLASDQSSPSTPSPPLPPEAAHFLFGEPTLRKRKSPA----- 196
            V  P   +S++ +         ++S+    + P P E+A F     TL +  SPA     
Sbjct: 1150 VPTPEESASAAVAVP-----TPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPT 1204

Query: 197  -QVMFQCLWKSCGKVLSTASAMQRHIRLVHLGRQAEPEQSDGEEDFYYTELDVGVDTLTD 255
               M   L +      S  ++ +       +    EP           T     V TL +
Sbjct: 1205 PAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEP-----------TSPAAAVPTLEE 1253

Query: 256  GLSS----LTP---VSPTASMP----PAFPRLELPELLEP----PALPSPLRPPAP---- 296
              SS    LTP    SP AS+P    PA P   +  L EP     A+P+P     P    
Sbjct: 1254 PTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASV 1313

Query: 297  PLPPPPVLSTVANP 310
            P P  P +   A P
Sbjct: 1314 PTPEVPAIPAAAVP 1327



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 84/353 (23%), Positives = 124/353 (35%), Gaps = 69/353 (19%)

Query: 26   EGPGPRAAPVTVPTPPQGSSVGGGFAGLEFARPQESEPRASDLGAPRTWTGAAAG----- 80
            EGP   A  V  P  P  ++V         + P+E    A+ +  P   T  AA      
Sbjct: 972  EGPVTPATTVHAPEEPDTAAV-------RVSTPEEPASPAAAVPTPEEPTSPAAAVPTPE 1024

Query: 81   -PRTPSAHIPVPAQRATPGKA--RLDEVMAAAALTSLSTSPLLLGAPV---------AAF 128
             P +P+A +P P +  +P  A    +E  + AA       P    A V         AA 
Sbjct: 1025 EPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA 1084

Query: 129  SPEPGLEPWKEALVRPPGSYSSSSNSGDWGWDLASDQSSPSTPSPPLPPEAAHFLFGEPT 188
             P P       A V  P   +S + +     + AS  ++  TP  P  P AA      PT
Sbjct: 1085 VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAA-----VPT 1139

Query: 189  LRKRKSPAQVMFQCLWKSCGKVLSTASAMQRHIRLVHLGRQAEPEQSDGEEDFYYTELDV 248
              +   PA  +      +  +  S A A+              PE+S        T  + 
Sbjct: 1140 PEEPAFPAPAV-----PTPEESASAAVAV------------PTPEESASPAAAVPTPAES 1182

Query: 249  G-----VDTLTDGLSSLTPVSPTASMP-PA----------FPRLELPELLEPPALPSPLR 292
                  V TL +      P SP AS+P PA           P   +P   EP +L + + 
Sbjct: 1183 ASFAAVVATLEE------PTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVS 1236

Query: 293  PPAPPLPPPPVLSTVANP-QSCHSDRVYQGCLTPARLEPQPTEVGACPPALSS 344
             P  P  P   + T+  P  S  +    +   +PA   P P E  +   A+S+
Sbjct: 1237 NPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSN 1289



 Score = 34.3 bits (77), Expect = 0.20
 Identities = 78/339 (23%), Positives = 118/339 (34%), Gaps = 77/339 (22%)

Query: 28   PGPRAAPVTVPTPPQGSSVGGGFAGLEFARPQESEPRASDLGAPRTWTGAAAGPRTPSAH 87
            P   A  V      +G S   GF+  E+A    + P   + G P        GP TP+  
Sbjct: 929  PEETAPAVAAAITQEGMSAVAGFSP-EWAALAITVPITEEDGTPE-------GPVTPATT 980

Query: 88   IPVPAQRATPGKARLDEVMAAAALTSLSTSPLLLGAPVAAF-SPEPGLEPWKEALVRPPG 146
            +  P +  T    R+      A+  +   +P    +P AA  +PE    P   A V PP 
Sbjct: 981  VHAPEEPDTAA-VRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSP--AAAVPPPE 1037

Query: 147  SYSSSSNSGDWGWDLASDQSSPSTPSPPLPPEAAHFLFGEPTLRKRKSPAQVMFQCLWKS 206
              +S + +     +  S  ++  TP  P  P AA      PT  +  SPA  +      +
Sbjct: 1038 EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA-----VPTPEEPTSPAAAV-----PT 1087

Query: 207  CGKVLSTASAMQRHIRLVHLGRQAEPEQSDGEEDFYYTELDVGVDTLTDGLSSLTPVSPT 266
              +  S A+A+              PE+                           P SP 
Sbjct: 1088 PEEPTSPAAAVPT------------PEE---------------------------PTSPA 1108

Query: 267  ASMP----PAFPRLELPELLEPPALPSPLRPPAPPLPPPPVLSTVANPQSCHSDRVY--- 319
            A++P    PA P   +P   EP +  + +  P  P  P P + T   P+   S  V    
Sbjct: 1109 AAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPT---PEESASAAVAVPT 1165

Query: 320  -QGCLTPARLEPQPTEVGACPPALSSRIGVTLRKPRGDA 357
             +   +PA   P P E      A  + +  TL +P   A
Sbjct: 1166 PEESASPAAAVPTPAE-----SASFAAVVATLEEPTSPA 1199



 Score = 30.8 bits (68), Expect = 2.2
 Identities = 30/118 (25%), Positives = 41/118 (34%), Gaps = 8/118 (6%)

Query: 26   EGPGPRAAPVTVPTPPQGSSVGGGFAGLEFARPQESEPRASDLGAPRTWTGAAAGPRTPS 85
            E   P AA  T+  P   SS        E + P  S P   +  +P         P +P+
Sbjct: 1240 EPTSPAAAVPTLEEPT--SSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPA 1297

Query: 86   AHIPVPAQRATPGKA----RLDEVMAAAALTSLSTSPLLLGAPVAAFSPEPGLEPWKE 139
            A +P P   A P  +     +  + AAA       SP  +G P    S      P  E
Sbjct: 1298 AAVPTPEVAAIPAASVPTPEVPAIPAAAVPPMEEVSP--IGVPFLGVSAHTDSVPISE 1353


>gi|7662302 TBK1 binding protein 1 [Homo sapiens]
          Length = 615

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 35/99 (35%), Positives = 45/99 (45%), Gaps = 13/99 (13%)

Query: 261 TPVSPTASMPPAFPRLELPELLEPPALPSPLRPPAPPLPPPPVLSTV-----ANPQSCHS 315
           +PV P+   P   P+   P    PP+ P+P   P PP PPPP   T+     A P S H 
Sbjct: 400 SPVPPSCQSPS--PQRRSPV---PPSCPAP--QPRPPPPPPPGERTLAERAYAKPPSHHV 452

Query: 316 DRVYQGCLTPARLEPQPTEVGACPPALSSRIGVTLRKPR 354
              +QG  + + L       GA PP L +    TL KPR
Sbjct: 453 KAGFQGRRSYSELAEGAAYAGASPPWLQAE-AATLPKPR 490



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 24/86 (27%), Positives = 33/86 (38%), Gaps = 5/86 (5%)

Query: 261 TPVSPTASMPPAFPRLELPELLEPPALP--SPL---RPPAPPLPPPPVLSTVANPQSCHS 315
           +P+S   S  P  P    P    PP  P  SP+   R P PP P P    + A+P     
Sbjct: 335 SPLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASPSCPSP 394

Query: 316 DRVYQGCLTPARLEPQPTEVGACPPA 341
               +  + P+   P P      PP+
Sbjct: 395 VPQRRSPVPPSCQSPSPQRRSPVPPS 420


>gi|28376656 zinc finger, X-linked, duplicated B [Homo sapiens]
          Length = 803

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 58/220 (26%), Positives = 84/220 (38%), Gaps = 41/220 (18%)

Query: 27  GPGPRAAPVTVPTPPQGSSVGGGFAGLEFARPQESEPRASDLGAPRTWTGAAAGPRTPSA 86
           G G  A PV      +G  + GG +G   A P                   A GPR  SA
Sbjct: 108 GSGQAAGPVLREEAEEGPGLQGGESGANPAGP------------------TALGPRCLSA 149

Query: 87  HIPVPAQRATPGKARLDEVMAAAALTSLSTSPLLL----GAPVAAFSP----EPGLEPWK 138
            +P PA  + PG A      A A   ++    LLL    G    A  P    EPG  P +
Sbjct: 150 -VPTPAPISAPGPA-----AAFAGTVTIHNQDLLLRFENGVLTLATPPPHAWEPGAAPAQ 203

Query: 139 E--ALVRPPGSYSSSSNSGDWGWDLASD--QSSPSTPSP-PLPPEAAHFLFGE--PTLRK 191
           +   L+ P   +  +++ GD   +L  D   + P+ P+P P P E A        P    
Sbjct: 204 QPGCLIAPQAGFPHAAHPGDCP-ELPPDLLLAEPAEPAPAPAPEEEAEGPAAALGPRGPL 262

Query: 192 RKSPAQVMFQCLWKSCGKVLSTASAMQRHIRLVHLGRQAE 231
              P  V++ C    CG+  +    ++ H+ L H   Q +
Sbjct: 263 GSGPGVVLYLCPEAQCGQTFAKKHQLKVHL-LTHSSSQGQ 301


>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
          Length = 1526

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 46/146 (31%), Positives = 58/146 (39%), Gaps = 24/146 (16%)

Query: 24   RAEGPGPRAAPVTVPTPPQGSS--------VGGGFAGLEFARPQESEPRASDLGAPRTWT 75
            R   P  R AP   P PP G S         G G AG   ARP    PRA  + AP++  
Sbjct: 1107 RPVAPPTRPAPPQRPPPPSGRSQPSPQAGLAGPGPAGYSTARP-TIPPRAGVISAPQSHA 1165

Query: 76   GAAAGPRTPSAHIPVPAQRATPGKARLDEVMAAAALTSLSTS----------PLLLGAPV 125
             A+AG  TP +         + G   L E +   A     +S          PL+   PV
Sbjct: 1166 RASAGRLTPESQ--SKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLV---PV 1220

Query: 126  AAFSPEPGLEPWKEALVRPPGSYSSS 151
            AA  P+ G +P  E   +PP    SS
Sbjct: 1221 AAPMPQSGPQPNLETPPQPPPRSRSS 1246



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 62/260 (23%), Positives = 78/260 (30%), Gaps = 48/260 (18%)

Query: 61   SEPRASDLGAPRTWTGAAAGPRTPSAHIPVPAQRATPGKARLDEVMAAAALTSLSTSPLL 120
            S PR S   +P    G    P  P      P++   P  A+   + A  A       P  
Sbjct: 1039 SSPRTSPCQSPTISEGPV--PSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQ 1096

Query: 121  LGAPVAAFSPEPGLEPWKEALVRPPGSYSSSSNSGDWGWDLASDQSSPSTPSPPLPPEAA 180
               P     P P   P + A  + P   S  S             +  ST  P +PP A 
Sbjct: 1097 PLEPKRPPPPRPVAPPTRPAPPQRPPPPSGRSQPSPQAGLAGPGPAGYSTARPTIPPRAG 1156

Query: 181  HFLFGEPTLRKRKSPAQVMFQCLWKSCGKVLSTASAMQRHIRLVHLGRQAEPEQSDGEED 240
                                              SA Q H R    GR     QS     
Sbjct: 1157 --------------------------------VISAPQSHAR-ASAGRLTPESQSKT--- 1180

Query: 241  FYYTELDVGVDTLTDGLSSLTPVSPTASMPPAFPRLELPELLEPPALPSPLRPP-----A 295
               +E   G   L + L       P +S+PP   RL+ P  L P A P P   P      
Sbjct: 1181 ---SETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEP--LVPVAAPMPQSGPQPNLET 1235

Query: 296  PPLPPPPVLSTVANPQSCHS 315
            PP PPP   S+ + P    S
Sbjct: 1236 PPQPPPRSRSSHSLPSEASS 1255


>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
          Length = 3571

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 41/163 (25%), Positives = 63/163 (38%), Gaps = 35/163 (21%)

Query: 206  SCGKVLSTASAMQRHIRLVHLGRQAEPEQSDGEEDFYYTELDVGVDTLTDGLSSLTPVSP 265
            +CGK+ S    ++ H   VH             + F Y  L+       +    L P+SP
Sbjct: 1905 TCGKLFSNVLILKSHQEHVH------------GQFFPYAALEKFARQYREAYDKLYPISP 1952

Query: 266  TAS-----------MPPAFPR------LELPE-----LLEPPALPSPLRPPAPPLPPPPV 303
            ++            +PPA P+      +++P      L  PP  P P  PP PP PPPP 
Sbjct: 1953 SSPETPPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPP 2012

Query: 304  LSTVANPQSCHSDRVYQGCLTPARLEPQPTEVGACPPALSSRI 346
                + P            L P+ +  QP +  A PP L+ ++
Sbjct: 2013 PPPPSAPPQVQLPVSLDLPLFPS-IMMQPVQHPALPPQLALQL 2054



 Score = 33.5 bits (75), Expect = 0.33
 Identities = 20/51 (39%), Positives = 26/51 (50%), Gaps = 7/51 (13%)

Query: 262  PVSPTASMPPAFPRLELPELLEPPALPSPLRPPAPPLPPPPVLSTVANPQS 312
            P S T+S     P L L      P L +P  PP PP PPPP  S+++  Q+
Sbjct: 3094 PTSATSS-----PALSLSSAPTKPLLQTP--PPPPPPPPPPPSSSLSGQQT 3137



 Score = 30.0 bits (66), Expect = 3.7
 Identities = 20/69 (28%), Positives = 28/69 (40%)

Query: 262  PVSPTASMPPAFPRLELPELLEPPALPSPLRPPAPPLPPPPVLSTVANPQSCHSDRVYQG 321
            P  P    P A P+++LP  L+ P  PS +  P      PP L+         S  + Q 
Sbjct: 2008 PPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLPQMDALSADLTQL 2067

Query: 322  CLTPARLEP 330
            C     L+P
Sbjct: 2068 CQQQLGLDP 2076


>gi|226371764 transcription factor 7-like 2 isoform 1 [Homo sapiens]
          Length = 602

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 15/29 (51%), Positives = 22/29 (75%)

Query: 358 KKCRKVYGMERRDLWCTACRWKKACQRFL 386
           KKCR ++G++R+ LWC  CR KK C R++
Sbjct: 445 KKCRALFGLDRQTLWCKPCRRKKKCVRYI 473


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 31/83 (37%), Positives = 38/83 (45%), Gaps = 19/83 (22%)

Query: 261 TPVSPTASMPPAFPRLELPELLEPPALPSPLRPP---APPLPPPPVLSTVANPQSCHSDR 317
           +P+SP    PP+ P LE P  L PP   SPL PP   +P  PPP  L T   P++     
Sbjct: 518 SPLSPPEESPPS-PALETP--LSPPPEASPLSPPFEESPLSPPPEELPTSPPPEA----- 569

Query: 318 VYQGCLTPARLEPQPTEVGACPP 340
                   +RL P P E    PP
Sbjct: 570 --------SRLSPPPEESPMSPP 584



 Score = 37.4 bits (85), Expect = 0.023
 Identities = 91/359 (25%), Positives = 118/359 (32%), Gaps = 71/359 (19%)

Query: 4   PPPRA--AGRDPSALRAEAPWLRAE-GPGPRAAPVTVPTPPQGSSVGGGFAGLEFARPQE 60
           PPP    A   P AL    P   +   P P  +P++   PP  SS          + P+E
Sbjct: 469 PPPEELPASPLPEALHLSRPLEESPLSPPPEESPLS---PPPESSPFSPLEESPLSPPEE 525

Query: 61  SEP------------RASDLGAPRTWTGAAAGPRTPSAHIPVPAQRATPGKARLDEVMAA 108
           S P             AS L  P   +  +  P       P  A R +P           
Sbjct: 526 SPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEE------- 578

Query: 109 AALTSLSTSPLLLGAPVAAFSPEPGLE----PWKEALVRPPGSYSSSSNSGDWGWDLASD 164
                   SP+      +  SP P       P++E+ + PP   S  S   +     AS 
Sbjct: 579 --------SPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPE-----ASR 625

Query: 165 QSSPSTPSPPLPPEAAHFLFGEPTLRKRKSPAQVMFQCLWKSCGKVLSTASAMQRHIRLV 224
            S P   SP  PP     +   P +  R SP  V+            S  S       L 
Sbjct: 626 LSPPPEDSPMSPPPEESPMSPPPEV-SRLSPLPVV------------SRLSPPPEESPL- 671

Query: 225 HLGRQAEPEQSDGEEDFYYTELDVGVDTLTDGLSSLTPVSPTASMPPAFPRLELPELLEP 284
                  PE+S        + L    +   D  +S  P    AS PP    + LP L E 
Sbjct: 672 ----SPPPEESPTSPPPEASRLSPPPE---DSPTSPPPEDSPASPPPEDSLMSLP-LEES 723

Query: 285 PALPSPLRPPAPPLPPPPVLSTVANPQSCH-SDRVYQGCLTP----ARLEPQPTEVGAC 338
           P LP P  P   P    P LS    P+  H S R  +  L+P      L PQP E   C
Sbjct: 724 PLLPLPEEPQLCPRSEGPHLS--PRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLC 780



 Score = 37.0 bits (84), Expect = 0.030
 Identities = 32/93 (34%), Positives = 40/93 (43%), Gaps = 7/93 (7%)

Query: 261 TPVSPTASMPPAFPRLELPELLEPPA-LPSPLRPPAPPLPPPPVLSTVANP--QSCHSDR 317
           TP+SP     P  P  E   L  PP  LP+   P A  L PPP  S ++ P  +S  S  
Sbjct: 534 TPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPP 593

Query: 318 VYQGCLTP----ARLEPQPTEVGACPPALSSRI 346
                L P    + L P P E    PP  +SR+
Sbjct: 594 PEASRLFPPFEESPLSPPPEESPLSPPPEASRL 626



 Score = 36.2 bits (82), Expect = 0.051
 Identities = 32/88 (36%), Positives = 39/88 (44%), Gaps = 9/88 (10%)

Query: 261 TPVSPTASMPPAFPRLELPELLEPPALPSPLRPP--APPLPPPPVLSTVANP--QSCHSD 316
           +P+SP       FP  E    L PP   SPL PP  A  L PPP  S ++ P  +S  S 
Sbjct: 588 SPMSPPPEASRLFPPFE-ESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSP 646

Query: 317 RVYQGCLTP----ARLEPQPTEVGACPP 340
                 L+P    +RL P P E    PP
Sbjct: 647 PPEVSRLSPLPVVSRLSPPPEESPLSPP 674



 Score = 35.4 bits (80), Expect = 0.088
 Identities = 28/93 (30%), Positives = 37/93 (39%), Gaps = 19/93 (20%)

Query: 261 TPVSPTASMPPAFPRLE---LPELLEPPALPSPLRPPAP----PLPPPPVLSTVANPQSC 313
           +P+SP     P  P  E      L E P  P    PP+P    PL PPP  S ++ P   
Sbjct: 492 SPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPP--- 548

Query: 314 HSDRVYQGCLTPARLEPQPTEVGACPPALSSRI 346
                       + L P P E+   PP  +SR+
Sbjct: 549 ---------FEESPLSPPPEELPTSPPPEASRL 572



 Score = 35.4 bits (80), Expect = 0.088
 Identities = 57/216 (26%), Positives = 76/216 (35%), Gaps = 34/216 (15%)

Query: 131  EPGLEPWKEAL--VRPPGSYSSSSNSGDWGWDLASDQSSPSTPSPPLPPEAAHFLFGEPT 188
            EPG  P  E L    PPG  S S   G+      S+   P  P  PLP E      GEP+
Sbjct: 870  EPGQCPAPEELPLFPPPGEPSLSPLLGE---PALSEPGEP--PLSPLPEELPLSPSGEPS 924

Query: 189  LRKRKSPAQVMFQCLWKSCGKVLSTASAMQRHIRLVHLGRQAEPEQSDGEEDFYYTELDV 248
            L  +  P   +   L       + TA+A      L  LG    P  + G+ D    E  +
Sbjct: 925  LSPQLMPPDPLPPPL-----SPIITAAAPPA---LSPLGELEYPFGAKGDSD---PESPL 973

Query: 249  GVDTLTDGLSSLTPVSPTASMPPAFPRLELPELLEPPALPSPLRPPAPPLPPPPVLSTVA 308
                L       TP+SP    PP           +P  +P  + PP+P  P  P    + 
Sbjct: 974  AAPILE------TPISP----PPE------ANCTDPEPVPPMILPPSPGSPVGPASPILM 1017

Query: 309  NPQSCHSDRVYQGCLTPARLEPQPTEVGACPPALSS 344
             P       + Q  L P    P      A P ++ S
Sbjct: 1018 EPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPS 1053



 Score = 35.4 bits (80), Expect = 0.088
 Identities = 69/272 (25%), Positives = 85/272 (31%), Gaps = 56/272 (20%)

Query: 106  MAAAALTSLSTSPLLLGAPVAAFSPEPG------LEPWKEALVRPPGSYSSSSNSGDW-- 157
            + + + +  S+ P LL  P  +   +PG      L P +  L RP       +N+G    
Sbjct: 4119 LGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERP-----MQNNTGPQPP 4173

Query: 158  --GWDLASDQSSPSTPSPP----LPPEAAHFLFGEPTLRKRKSPAQVMFQCLWKSCGKVL 211
              G  L S Q  P     P    L  +    L   P LR      Q   Q L        
Sbjct: 4174 KPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQAL-------- 4225

Query: 212  STASAMQRHIRLVHLGRQAEPEQSDGEEDFYYTELDVGVDTLTDGLSSLTPVSPTASMPP 271
                 MQR ++     RQ  P Q  G              T T  L  L    P      
Sbjct: 4226 ----LMQRQLQQSQAVRQTPPYQEPG--------------TQTSPLQGLLGCQPQLG--- 4264

Query: 272  AFPRLELPELLEPPALPSPLRPPAPPLPP-----PPVLSTV-ANPQSCHSDRVYQGCLTP 325
             FP  +   L E  A P P  PP  P PP      PVL  V   P         +    P
Sbjct: 4265 GFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLP 4324

Query: 326  ARLEPQPTEVGACP--PALSSRIGVTLRKPRG 355
            +     PTE    P  P      G TL  P G
Sbjct: 4325 SPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPG 4356



 Score = 33.5 bits (75), Expect = 0.33
 Identities = 84/364 (23%), Positives = 117/364 (32%), Gaps = 102/364 (28%)

Query: 16  LRAEAPWLRAEGPGPRAAPVTVPTPPQGSSVGGGFAGLEFARPQESEPRASDLGAPRTWT 75
           L  E P L    P P  +P++   PP+ S             P    P AS L  P    
Sbjct: 434 LNEEMPLL----PPPEESPLS--PPPEES-------------PTSPPPEASRLSPPPE-- 472

Query: 76  GAAAGPRTPSAHIPVPAQRAT----PGKARLDEVMAAAALTSLSTSPLLLGAPVAAFSPE 131
              A P   + H+  P + +     P ++ L     ++  + L  SPL   +P     P 
Sbjct: 473 ELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPL---SPPEESPPS 529

Query: 132 PGLE--------------PWKEALVRPPGSYSSSSNSGDWGWDLASDQSSPSTP----SP 173
           P LE              P++E+ + PP     +S   +        + SP +P    SP
Sbjct: 530 PALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESP 589

Query: 174 PLPPEAAHFLFGEPTLRKRKSPAQVMFQCLWKSCGKVLSTASAMQRHIRLVHLGRQAEPE 233
             PP  A  LF  P      SP                                    PE
Sbjct: 590 MSPPPEASRLF-PPFEESPLSPP-----------------------------------PE 613

Query: 234 QSDGEEDFYYTELDVGVDTLTDGLSSLTPVSPTASMPPAFPRLE-LPEL--LEPPALPSP 290
           +S        + L    +   D   S  P     S PP   RL  LP +  L PP   SP
Sbjct: 614 ESPLSPPPEASRLSPPPE---DSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESP 670

Query: 291 LRPP--APPLPPPPVLSTVANPQSCHSDRVYQGCLTPARLEPQPTEVGACPPALSSRIGV 348
           L PP    P  PPP  S ++ P               +   P P +  A PP   S + +
Sbjct: 671 LSPPPEESPTSPPPEASRLSPPPE------------DSPTSPPPEDSPASPPPEDSLMSL 718

Query: 349 TLRK 352
            L +
Sbjct: 719 PLEE 722



 Score = 33.5 bits (75), Expect = 0.33
 Identities = 93/388 (23%), Positives = 131/388 (33%), Gaps = 97/388 (25%)

Query: 4   PPPRAAGRDPSALRAEAPWLRAEGPGPRAAPVTVPTPPQGSSVGGGFAGLEFARPQESEP 63
           PPP A+   P     E+P      P P  +P++   PP+ S +   F     + P E  P
Sbjct: 565 PPPEASRLSPPP--EESPM----SPPPEESPMS--PPPEASRLFPPFEESPLSPPPEESP 616

Query: 64  RASDLGAPRTWTGAAAGPRTPSAHIPVPAQRATPGKARLDEVMAAAALTSLSTSPLLLGA 123
            +    A R        P +P    P  +  + P +           ++ LS  P+    
Sbjct: 617 LSPPPEASRLSPPPEDSPMSPP---PEESPMSPPPE-----------VSRLSPLPV---- 658

Query: 124 PVAAFSPEPGLEPWKEALVRPPGSYSSSSNSGDWGWDLASDQSSPSTPSP---PLPPEAA 180
            V+  SP P     +E+ + PP   S +S   +        + SP++P P   P  P   
Sbjct: 659 -VSRLSPPP-----EESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPE 712

Query: 181 HFLFGEPTLRKRKSPAQVMFQCLWKSCGKVLS-----------------TASAMQRHI-- 221
             L   P       P     Q   +S G  LS                 +  A + H+  
Sbjct: 713 DSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSP 772

Query: 222 -----------RLVHLGRQAE-PEQSDGEEDFYYTELDVGVDTLTDGLSS------LTP- 262
                         HL  QAE P  S   E     EL +   T    LS       L+P 
Sbjct: 773 QPEEPCLCAVPEEPHLSPQAEGPHLSPQPE-----ELHLSPQTEEPHLSPVPEEPCLSPQ 827

Query: 263 -----VSPTASMPPAFPRLE----LPELLEPPALPSPLRPPAPP--LPPPPVLSTVANPQ 311
                +SP +  P   PR E     PEL +PP  P P +PP  P   P P  L     P 
Sbjct: 828 PEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPG 887

Query: 312 SCHSDRVYQGCLTPARLEPQPTEVGACP 339
                   +  L+P   EP  +E G  P
Sbjct: 888 --------EPSLSPLLGEPALSEPGEPP 907



 Score = 32.7 bits (73), Expect = 0.57
 Identities = 30/87 (34%), Positives = 35/87 (40%), Gaps = 20/87 (22%)

Query: 274 PRLELPELLEPPALPSP----LRPP------APP------LPPPPVLSTVANPQSCHSDR 317
           P+LE P   E P LP P    L PP      +PP       PPP  L     P++ H  R
Sbjct: 428 PQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSR 487

Query: 318 VYQGCLTPARLEPQPTEVGACPPALSS 344
                L  + L P P E    PP  SS
Sbjct: 488 P----LEESPLSPPPEESPLSPPPESS 510



 Score = 32.3 bits (72), Expect = 0.74
 Identities = 16/38 (42%), Positives = 24/38 (63%), Gaps = 1/38 (2%)

Query: 261  TPVSPTASMPPAFPRLELP-ELLEPPALPSPLRPPAPP 297
            +P++P+ + PP  P +ELP E L  P +PSPL   + P
Sbjct: 4919 SPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSP 4956



 Score = 30.8 bits (68), Expect = 2.2
 Identities = 26/92 (28%), Positives = 35/92 (38%), Gaps = 10/92 (10%)

Query: 262  PVSPTASMPPAFPRLELPELLEPPALPSPLRPPAPPLPPPPVLSTVANPQSCHSDRVYQG 321
            P    A  PP+ P +  P     P    PL P     PPPP       P+S  SD   + 
Sbjct: 2354 PAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQ--PPPPESCCALPPRSLPSDPFSRV 2411

Query: 322  CLTP-------ARLEPQPTEVGA-CPPALSSR 345
              +P       + L P+P    A CP  ++ R
Sbjct: 2412 PASPQSQSSSQSPLTPRPLSAEAFCPSPVTPR 2443



 Score = 28.9 bits (63), Expect = 8.2
 Identities = 28/104 (26%), Positives = 37/104 (35%), Gaps = 18/104 (17%)

Query: 262  PVSPTASMPPAFPRLE---LPELLEPPALPSPLRPPAPPLPPPPV--LSTVANPQSCHSD 316
            P+SP     P  P  E    P+L+ P  LP PL P      PP +  L  +  P     D
Sbjct: 907  PLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGD 966

Query: 317  RVYQGCLTPARLE-------------PQPTEVGACPPALSSRIG 347
               +  L    LE             P+P      PP+  S +G
Sbjct: 967  SDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVG 1010


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.132    0.421 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,722,789
Number of Sequences: 37866
Number of extensions: 1446935
Number of successful extensions: 20006
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 367
Number of HSP's successfully gapped in prelim test: 863
Number of HSP's that attempted gapping in prelim test: 11255
Number of HSP's gapped (non-prelim): 6440
length of query: 387
length of database: 18,247,518
effective HSP length: 104
effective length of query: 283
effective length of database: 14,309,454
effective search space: 4049575482
effective search space used: 4049575482
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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