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Search of human proteins with 31377639
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31377639 sialic acid binding Ig-like lectin 10 [Homo
sapiens]
(697 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31377639 sialic acid binding Ig-like lectin 10 [Homo sapiens] 1429 0.0
gi|205830470 sialic acid binding Ig-like lectin 11 isoform 1 [Ho... 954 0.0
gi|205830473 sialic acid binding Ig-like lectin 11 isoform 2 [Ho... 730 0.0
gi|94538343 sialic acid binding Ig-like lectin 8 [Homo sapiens] 288 2e-77
gi|4502659 sialic acid binding Ig-like lectin 5 [Homo sapiens] 280 4e-75
gi|148762980 sialic acid binding Ig-like lectin 14 [Homo sapiens] 273 5e-73
gi|16506828 sialic acid binding immunoglobulin-like lectin-like ... 272 7e-73
gi|16506826 sialic acid binding immunoglobulin-like lectin-like ... 272 9e-73
gi|7657570 sialic acid binding Ig-like lectin 7 isoform 1 [Homo ... 271 1e-72
gi|23943856 sialic acid binding Ig-like lectin 9 [Homo sapiens] 262 9e-70
gi|193794821 sialic acid binding Ig-like lectin 6 isoform 1 prec... 257 3e-68
gi|193794817 sialic acid binding Ig-like lectin 6 isoform 3 prec... 253 5e-67
gi|193794819 sialic acid binding Ig-like lectin 6 isoform 2 prec... 235 1e-61
gi|130979981 CD33 antigen isoform 1 precursor [Homo sapiens] 233 3e-61
gi|11225258 myelin associated glycoprotein isoform a precursor [... 190 3e-48
gi|18104957 myelin associated glycoprotein isoform b precursor [... 190 3e-48
gi|118197279 sialic acid binding Ig-like lectin 7 isoform 2 [Hom... 130 3e-30
gi|13489095 sialoadhesin precursor [Homo sapiens] 108 2e-23
gi|130980072 CD33 antigen isoform 2 precursor [Homo sapiens] 105 2e-22
gi|27735027 hypothetical protein LOC284369 [Homo sapiens] 95 2e-19
gi|157168355 CD22 molecule [Homo sapiens] 95 3e-19
gi|118572606 hemicentin 1 [Homo sapiens] 91 5e-18
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 90 6e-18
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 90 6e-18
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 90 6e-18
gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo sapi... 83 8e-16
gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo sap... 83 8e-16
gi|109150416 peroxidasin [Homo sapiens] 82 1e-15
gi|33519481 neural cell adhesion molecule 2 precursor [Homo sapi... 82 1e-15
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens] 81 3e-15
>gi|31377639 sialic acid binding Ig-like lectin 10 [Homo sapiens]
Length = 697
Score = 1429 bits (3698), Expect = 0.0
Identities = 697/697 (100%), Positives = 697/697 (100%)
Query: 1 MLLPLLLSSLLGGSQAMDGRFWIRVQESVMVPEGLCISVPCSFSYPRQDWTGSTPAYGYW 60
MLLPLLLSSLLGGSQAMDGRFWIRVQESVMVPEGLCISVPCSFSYPRQDWTGSTPAYGYW
Sbjct: 1 MLLPLLLSSLLGGSQAMDGRFWIRVQESVMVPEGLCISVPCSFSYPRQDWTGSTPAYGYW 60
Query: 61 FKAVTETTKGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFRV 120
FKAVTETTKGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFRV
Sbjct: 61 FKAVTETTKGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFRV 120
Query: 121 ERGSYVRYNFMNDGFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFEECPPPSFSW 180
ERGSYVRYNFMNDGFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFEECPPPSFSW
Sbjct: 121 ERGSYVRYNFMNDGFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFEECPPPSFSW 180
Query: 181 TGAALSSQGTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRD 240
TGAALSSQGTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRD
Sbjct: 181 TGAALSSQGTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRD 240
Query: 241 LVISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHP 300
LVISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHP
Sbjct: 241 LVISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHP 300
Query: 301 WGPRPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLE 360
WGPRPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLE
Sbjct: 301 WGPRPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLE 360
Query: 361 NLGNGTSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSDPGVLELPRVQVEHE 420
NLGNGTSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSDPGVLELPRVQVEHE
Sbjct: 361 NLGNGTSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSDPGVLELPRVQVEHE 420
Query: 421 GEFTCHARHPLGSQHVSLSLSVHYSPKLLGPSCSWEAEGLHCSCSSQASPAPSLRWWLGE 480
GEFTCHARHPLGSQHVSLSLSVHYSPKLLGPSCSWEAEGLHCSCSSQASPAPSLRWWLGE
Sbjct: 421 GEFTCHARHPLGSQHVSLSLSVHYSPKLLGPSCSWEAEGLHCSCSSQASPAPSLRWWLGE 480
Query: 481 ELLEGNSSQDSFEVTPSSAGPWANSSLSLHGGLSSGLRLRCEAWNVHGAQSGSILQLPDK 540
ELLEGNSSQDSFEVTPSSAGPWANSSLSLHGGLSSGLRLRCEAWNVHGAQSGSILQLPDK
Sbjct: 481 ELLEGNSSQDSFEVTPSSAGPWANSSLSLHGGLSSGLRLRCEAWNVHGAQSGSILQLPDK 540
Query: 541 KGLISTAFSNGAFLGIGITALLFLCLALIIMKILPKRRTQTETPRPRFSRHSTILDYINV 600
KGLISTAFSNGAFLGIGITALLFLCLALIIMKILPKRRTQTETPRPRFSRHSTILDYINV
Sbjct: 541 KGLISTAFSNGAFLGIGITALLFLCLALIIMKILPKRRTQTETPRPRFSRHSTILDYINV 600
Query: 601 VPTAGPLAQKRNQKATPNSPRTPLPPGAPSPESKKNQKKQYQLPSFPEPKSSTQAPESQE 660
VPTAGPLAQKRNQKATPNSPRTPLPPGAPSPESKKNQKKQYQLPSFPEPKSSTQAPESQE
Sbjct: 601 VPTAGPLAQKRNQKATPNSPRTPLPPGAPSPESKKNQKKQYQLPSFPEPKSSTQAPESQE 660
Query: 661 SQEELHYATLNFPGVRPRPEARMPKGTQADYAEVKFQ 697
SQEELHYATLNFPGVRPRPEARMPKGTQADYAEVKFQ
Sbjct: 661 SQEELHYATLNFPGVRPRPEARMPKGTQADYAEVKFQ 697
>gi|205830470 sialic acid binding Ig-like lectin 11 isoform 1 [Homo
sapiens]
Length = 698
Score = 954 bits (2466), Expect = 0.0
Identities = 489/695 (70%), Positives = 545/695 (78%), Gaps = 36/695 (5%)
Query: 1 MLLPLLLSSLLGGSQAMDGRFWIRVQESVMVPEGLCISVPCSFSYPRQDWTGSTPAYGYW 60
+LLPLLL L GS D + ++VQ V VPEGLC+ V C+ SYPR W ST AYGYW
Sbjct: 14 LLLPLLLPVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAYGYW 73
Query: 61 FKAVTETTKGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFRV 120
FK T GAPVATN+QSREVEMSTR RFQLTGDP KG+CSLVIRDAQ +DE+ YFFRV
Sbjct: 74 FKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRV 133
Query: 121 ERGSYVRYNFMNDGFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFEECPPPSFSW 180
ERGS VR++F+++ FFLKVTALT+KPDVYIPETLEPGQPVTVICVFNWAF++CP PSFSW
Sbjct: 134 ERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSW 193
Query: 181 TGAALSSQGTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRD 240
TGAALS + T+P+TSHFSVLSFTP PQDH+TDLTCHVDFSRKGVSAQRTVRLRVAYAP+D
Sbjct: 194 TGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKD 253
Query: 241 LVISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHP 300
L+ISIS DNT ALE Q GNV YLE QKGQFLRLLCAADSQPPATLSWVLQ+RVLSSSHP
Sbjct: 254 LIISISHDNTSALELQ--GNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHP 311
Query: 301 WGPRPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLE 360
WGPR LGLEL GV+AGDSGRYTCRAENRLGSQQ+ALDLSVQYPPENLRVMVSQANRTVLE
Sbjct: 312 WGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLE 371
Query: 361 NLGNGTSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSDPGVLELPRVQVEHE 420
NLGNGTSLPVLEGQSL LVCVTHSSPPARLSWT+ GQ + PSQPSDPGVLELP +Q+EHE
Sbjct: 372 NLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHE 431
Query: 421 GEFTCHARHPLGSQHVSLSLSVHYSPKLLGPSCSWEAEGLHCSCSSQASPAPSLRWWLGE 480
GEFTCHA+HPLGSQHVSLSLSVHY P+LLGPSCSWEAEGLHCSCSSQASPAPSLRWWLGE
Sbjct: 432 GEFTCHAQHPLGSQHVSLSLSVHYPPQLLGPSCSWEAEGLHCSCSSQASPAPSLRWWLGE 491
Query: 481 ELLEGNSSQDSFEVTPSSAGPWANSSLSLHGGLSSGLRLRCEAWNVHGAQSGSILQLPDK 540
ELLEGNSSQ SFEVTPSSAGPWANSSLSLHGGLSSGLRLRC+AWNVHGAQSGS+ QL
Sbjct: 492 ELLEGNSSQGSFEVTPSSAGPWANSSLSLHGGLSSGLRLRCKAWNVHGAQSGSVFQLLPG 551
Query: 541 KGLISTAFSNGAFLGIGITALLFLCLALIIMKILPKRRTQTETPRPRFSRHSTILDYINV 600
K GA LG G+ ALL C L++ ++ R+ R R + +V
Sbjct: 552 KLEHGGGLGLGAALGAGVAALLAFCSCLVVFRVKICRKEA----RKRAAAEQ------DV 601
Query: 601 VPTAGPLAQKRNQKATPNSPRTPLPPGAPSPESKKNQKKQYQLPSFPEPKSSTQAPESQE 660
T GP++Q + + S + PPGA +T P E
Sbjct: 602 PSTLGPISQGHQHECSAGSSQDHPPPGA-----------------------ATYTPGKGE 638
Query: 661 SQEELHYATLNFPGVRPRPEARMPKGTQADYAEVK 695
QE LHYA+L+F G+R A + +Y+E+K
Sbjct: 639 EQE-LHYASLSFQGLRLWEPADQEAPSTTEYSEIK 672
>gi|205830473 sialic acid binding Ig-like lectin 11 isoform 2 [Homo
sapiens]
Length = 602
Score = 730 bits (1885), Expect = 0.0
Identities = 360/444 (81%), Positives = 393/444 (88%), Gaps = 2/444 (0%)
Query: 1 MLLPLLLSSLLGGSQAMDGRFWIRVQESVMVPEGLCISVPCSFSYPRQDWTGSTPAYGYW 60
+LLPLLL L GS D + ++VQ V VPEGLC+ V C+ SYPR W ST AYGYW
Sbjct: 14 LLLPLLLPVLGAGSLNKDPSYSLQVQRQVPVPEGLCVIVSCNLSYPRDGWDESTAAYGYW 73
Query: 61 FKAVTETTKGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFRV 120
FK T GAPVATN+QSREVEMSTR RFQLTGDP KG+CSLVIRDAQ +DE+ YFFRV
Sbjct: 74 FKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTGDPGKGSCSLVIRDAQREDEAWYFFRV 133
Query: 121 ERGSYVRYNFMNDGFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFEECPPPSFSW 180
ERGS VR++F+++ FFLKVTALT+KPDVYIPETLEPGQPVTVICVFNWAF++CP PSFSW
Sbjct: 134 ERGSRVRHSFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSW 193
Query: 181 TGAALSSQGTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRD 240
TGAALS + T+P+TSHFSVLSFTP PQDH+TDLTCHVDFSRKGVSAQRTVRLRVAYAP+D
Sbjct: 194 TGAALSPRRTRPSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKD 253
Query: 241 LVISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHP 300
L+ISIS DNT ALE QGNV YLE QKGQFLRLLCAADSQPPATLSWVLQ+RVLSSSHP
Sbjct: 254 LIISISHDNTSALE--LQGNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHP 311
Query: 301 WGPRPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLE 360
WGPR LGLEL GV+AGDSGRYTCRAENRLGSQQ+ALDLSVQYPPENLRVMVSQANRTVLE
Sbjct: 312 WGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLE 371
Query: 361 NLGNGTSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSDPGVLELPRVQVEHE 420
NLGNGTSLPVLEGQSL LVCVTHSSPPARLSWT+ GQ + PSQPSDPGVLELP +Q+EHE
Sbjct: 372 NLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHE 431
Query: 421 GEFTCHARHPLGSQHVSLSLSVHY 444
GEFTCHA+HPLGSQHVSLSLSVH+
Sbjct: 432 GEFTCHAQHPLGSQHVSLSLSVHW 455
Score = 122 bits (307), Expect = 9e-28
Identities = 116/397 (29%), Positives = 165/397 (41%), Gaps = 70/397 (17%)
Query: 322 TCRAE-NRLG-SQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLV 379
TC + +R G S QR + L V Y P++L + +S N + LE GN L V +GQ L L+
Sbjct: 227 TCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQGNVIYLEVQKGQFLRLL 286
Query: 380 CVTHSSPPARLSWTQRGQVLSPSQPSDPGVL--ELPRVQVEHEGEFTCHARHPLGSQHVS 437
C S PPA LSW + +VLS S P P L EL V+ G +TC A + LGSQ +
Sbjct: 287 CAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQA 346
Query: 438 LSLSVHYSPKLLGPSCSW------------------EAEGLHCSCSSQASPAPSLRWWLG 479
L LSV Y P+ L S E + L C + +SP L W
Sbjct: 347 LDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTHSSPPARLSWTRW 406
Query: 480 EELLEGNSSQDSFEVTPSSAGPWANSSLSL-HGGLSSGLRLRCEAWNVHGAQSGSILQLP 538
+ + + PS G + + H G C A + G+Q S+
Sbjct: 407 GQTVGPSQ--------PSDPGVLELPPIQMEHEG-----EFTCHAQHPLGSQHVSLSLSV 453
Query: 539 DKKGLISTAFSNGAFLGIGITALLFLCLALIIMKILPKRRTQTETPRPRFSRHSTILDYI 598
K GA LG G+ ALL C L++ ++ R+ R R +
Sbjct: 454 HWKLEHGGGLGLGAALGAGVAALLAFCSCLVVFRVKICRKEA----RKRAAAEQ------ 503
Query: 599 NVVPTAGPLAQKRNQKATPNSPRTPLPPGAPSPESKKNQKKQYQLPSFPEPKSSTQAPES 658
+V T GP++Q + + S + PPGA +T P
Sbjct: 504 DVPSTLGPISQGHQHECSAGSSQDHPPPGA-----------------------ATYTPGK 540
Query: 659 QESQEELHYATLNFPGVRPRPEARMPKGTQADYAEVK 695
E QE LHYA+L+F G+R A + +Y+E+K
Sbjct: 541 GEEQE-LHYASLSFQGLRLWEPADQEAPSTTEYSEIK 576
Score = 80.9 bits (198), Expect = 4e-15
Identities = 62/194 (31%), Positives = 92/194 (47%), Gaps = 12/194 (6%)
Query: 154 LEPGQPVTVICVFNWAFEECPPPSFSWTGAALSSQGTKPTTSHFSVLSFTPRPQDHNTDL 213
++ GQ + ++C A + PP + SW + P L +
Sbjct: 277 VQKGQFLRLLC----AADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRY 332
Query: 214 TCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEPQPQG-NVPYLEAQKGQFL 272
TC + +R G S Q+ + L V Y P +L + +S+ N LE G ++P LE GQ L
Sbjct: 333 TCRAE-NRLG-SQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLE---GQSL 387
Query: 273 RLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLGLELPGVKAGDSGRYTCRAENRLGSQ 332
RL+C S PPA LSW + + S P P L ELP ++ G +TC A++ LGSQ
Sbjct: 388 RLVCVTHSSPPARLSWTRWGQTVGPSQPSDPGVL--ELPPIQMEHEGEFTCHAQHPLGSQ 445
Query: 333 QRALDLSVQYPPEN 346
+L LSV + E+
Sbjct: 446 HVSLSLSVHWKLEH 459
>gi|94538343 sialic acid binding Ig-like lectin 8 [Homo sapiens]
Length = 499
Score = 288 bits (736), Expect = 2e-77
Identities = 171/392 (43%), Positives = 224/392 (57%), Gaps = 21/392 (5%)
Query: 1 MLLPLLLSSLLGGSQAMDGR------FWIRVQESVMVPEGLCISVPCSFSYPRQDWTGST 54
MLL LLL LL G++ M+G + ++VQE V V EGLC+ VPCSFSYP+ WT S
Sbjct: 1 MLLLLLLLPLLWGTKGMEGDRQYGDGYLLQVQELVTVQEGLCVHVPCSFSYPQDGWTDSD 60
Query: 55 PAYGYWFKAVTETTKGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDES 114
P +GYWF+A + APVATN+ REV+ T+GRFQL GD +CSL IRDA+ +D+
Sbjct: 61 PVHGYWFRAGDRPYQDAPVATNNPDREVQAETQGRFQLLGDIWSNDCSLSIRDARKRDKG 120
Query: 115 QYFFRVERGSY-----VRYNFMNDGFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNWA 169
YFFR+ERGS + N+ + VTALT +PD+ I TLE G + C WA
Sbjct: 121 SYFFRLERGSMKWSYKSQLNYKTKQLSVFVTALTHRPDILILGTLESGHSRNLTCSVPWA 180
Query: 170 FEECPPPSFSWTGAALSSQGTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRT 229
++ PP SW GA++SS G PTT+ SVL+ TP+PQDH T LTC V GV+ T
Sbjct: 181 CKQGTPPMISWIGASVSSPG--PTTARSSVLTLTPKPQDHGTSLTCQVTLPGTGVTTTST 238
Query: 230 VRLRVAYAPRDLVISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWV 289
VRL V+Y P +L +++ + + A GN L +GQ LRL+CA +S PPA LSW
Sbjct: 239 VRLDVSYPPWNLTMTVFQGDATA--STALGNGSSLSVLEGQSLRLVCAVNSNPPARLSWT 296
Query: 290 LQNRVLSSSHPWGPRPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRV 349
+ L S P LELP V D G +TCRA+N GSQ +L LS+Q
Sbjct: 297 RGSLTLCPSR--SSNPGLLELPRVHVRDEGEFTCRAQNAQGSQHISLSLSLQNEGTGTSR 354
Query: 350 MVSQANRTVLENLGNGTSLPVLEGQSLCLVCV 381
VSQ + G T+L L S C++ +
Sbjct: 355 PVSQVTLAAVGGAG-ATALAFL---SFCIIFI 382
Score = 127 bits (320), Expect = 3e-29
Identities = 79/182 (43%), Positives = 99/182 (54%), Gaps = 8/182 (4%)
Query: 267 QKGQFLRLLC----AADSQPPATLSWVLQNRVLSSSHPWGPRPLGLELPGVKAGDSGRYT 322
+ G L C A P +SW+ +SS P R L L T
Sbjct: 166 ESGHSRNLTCSVPWACKQGTPPMISWI--GASVSSPGPTTARSSVLTLTPKPQDHGTSLT 223
Query: 323 CRAE--NRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVC 380
C+ + + L V YPP NL + V Q + T LGNG+SL VLEGQSL LVC
Sbjct: 224 CQVTLPGTGVTTTSTVRLDVSYPPWNLTMTVFQGDATASTALGNGSSLSVLEGQSLRLVC 283
Query: 381 VTHSSPPARLSWTQRGQVLSPSQPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSL 440
+S+PPARLSWT+ L PS+ S+PG+LELPRV V EGEFTC A++ GSQH+SLSL
Sbjct: 284 AVNSNPPARLSWTRGSLTLCPSRSSNPGLLELPRVHVRDEGEFTCRAQNAQGSQHISLSL 343
Query: 441 SV 442
S+
Sbjct: 344 SL 345
Score = 45.8 bits (107), Expect = 1e-04
Identities = 104/424 (24%), Positives = 153/424 (36%), Gaps = 94/424 (22%)
Query: 308 LELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTS 367
L + + D G Y R E GS + + + Y + L V V T L + +
Sbjct: 109 LSIRDARKRDKGSYFFRLER--GSMKWSYKSQLNYKTKQLSVFV-----TALTHRPDILI 161
Query: 368 LPVLE-GQSLCLVC----VTHSSPPARLSWTQRGQVLSPSQPSDP--GVLELPRVQVEHE 420
L LE G S L C P +SW G +S P+ VL L +H
Sbjct: 162 LGTLESGHSRNLTCSVPWACKQGTPPMISWI--GASVSSPGPTTARSSVLTLTPKPQDHG 219
Query: 421 GEFTCHARHPLGSQHVSLS---LSVHYSPKLL-----------------GPSCS-WEAEG 459
TC P G+ + S L V Y P L G S S E +
Sbjct: 220 TSLTCQVTLP-GTGVTTTSTVRLDVSYPPWNLTMTVFQGDATASTALGNGSSLSVLEGQS 278
Query: 460 LHCSCSSQASPAPSLRWWLGEELLEGNSSQDSFEVTPS-SAGPWANSSLSLHGGLSSGLR 518
L C+ ++P L W G S + PS S+ P +H +
Sbjct: 279 LRLVCAVNSNPPARLSWTRG-----------SLTLCPSRSSNPGLLELPRVH--VRDEGE 325
Query: 519 LRCEAWNVHGAQSGSI-LQLPDKKGLISTAFSN---GAFLGIGITALLFLCLALIIMKIL 574
C A N G+Q S+ L L ++ S S A G G TAL FL +I + +
Sbjct: 326 FTCRAQNAQGSQHISLSLSLQNEGTGTSRPVSQVTLAAVGGAGATALAFLSFCIIFIIV- 384
Query: 575 PKRRTQTETPRPRFSRHSTILDYINVV---PTAGPLAQKRNQKATPNSPRTPLPPGAPSP 631
R + ++ RP T ++ + + GPL + +P PP
Sbjct: 385 --RSCRKKSARPAAGVGDTGMEDAKAIRGSASQGPLTESWKD----GNPLKKPPPAV--- 435
Query: 632 ESKKNQKKQYQLPSFPEPKSSTQAPESQESQEELHYATLNFPGVRPRPEARMPKGTQADY 691
AP S E + ELHYATL+F V+P+ + + + T ++Y
Sbjct: 436 -----------------------APSSGE-EGELHYATLSFHKVKPQ-DPQGQEATDSEY 470
Query: 692 AEVK 695
+E+K
Sbjct: 471 SEIK 474
>gi|4502659 sialic acid binding Ig-like lectin 5 [Homo sapiens]
Length = 551
Score = 280 bits (715), Expect = 4e-75
Identities = 173/419 (41%), Positives = 232/419 (55%), Gaps = 26/419 (6%)
Query: 260 NVPYLEA-QKGQFLRLLCA----ADSQPPATLSWVLQNRVLSSSHPWGPRPLGLELPGVK 314
++ +LE + G+ RL C+ ++ PP T SW LS P R L L
Sbjct: 147 DIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWT--GNALSPLDPETTRSSELTLTPRP 204
Query: 315 AGDSGRYTCRAENRLGSQ---QRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVL 371
TC+ + R G+Q +R + L+V Y P+ + + N LE L N + LPVL
Sbjct: 205 EDHGTNLTCQMK-RQGAQVTTERTVQLNVSYAPQTITIF---RNGIALEILQNTSYLPVL 260
Query: 372 EGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSDPGVLELPRVQVEHEGEFTCHARHPL 431
EGQ+L L+C S+PPA LSW Q L+ + S+ G+LEL RV+ EG FTC A+HPL
Sbjct: 261 EGQALRLLCDAPSNPPAHLSWFQGSPALNATPISNTGILELRRVRSAEEGGFTCRAQHPL 320
Query: 432 GSQHVSLSLSVHYSPKLLGPSCSWEAEGLHCSCSSQASPAPSLRWWLGEELLEGNSSQDS 491
G + L+LSV+ P+LLGPSCSWEAEGLHC CS +A PAPSL W L E+ LEGNSSQ S
Sbjct: 321 GFLQIFLNLSVYSLPQLLGPSCSWEAEGLHCRCSFRARPAPSLCWRLEEKPLEGNSSQGS 380
Query: 492 FEVTPSSAGPWANSSLSLHGGLSSGLRLRCEAWNVHGAQSGSILQLPDKKGLISTAFSNG 551
F+V SSAGPWANSSL LHGGLSS L++ C+AWN++G+QSGS+L L + L T
Sbjct: 381 FKVNSSSAGPWANSSLILHGGLSSDLKVSCKAWNIYGSQSGSVLLLQGRSNL-GTGVVPA 439
Query: 552 AFLGIGITALLFLCLALIIMKILPKRRTQTETPRPRFSRHSTILDYINVVPTAGPLAQKR 611
A G G+ ALL +CL LI I+ RR Q + P G +
Sbjct: 440 ALGGAGVMALLCICLCLIFFLIVKARRKQAAGRPEKMDDED---------PIMGTITSGS 490
Query: 612 NQKATPNSPRTPLPPGAPSPESKKNQKKQYQLPSFPEPKSSTQAPESQESQEELHYATL 670
+K P+SP P +P ++ ++ Y SF E KS + P+ QE+ Y+ +
Sbjct: 491 RKKPWPDSPGDQASPPGDAPPLEEQKELHYASLSFSEMKS--REPKDQEAPSTTEYSEI 547
Score = 262 bits (669), Expect = 9e-70
Identities = 158/347 (45%), Positives = 209/347 (60%), Gaps = 10/347 (2%)
Query: 2 LLPLLLSSLL-GGSQAMDGRFWIRVQESVMVPEGLCISVPCSFSYPRQDWTGSTPAYGYW 60
+LPLLL LL GGS + ++VQ+SV V EGLC+ VPCSFSYP + W S P Y YW
Sbjct: 1 MLPLLLLPLLWGGSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYW 60
Query: 61 FKAVTETTKGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFRV 120
F+ VATN+ R V+ T+GRF+L GD K NCSL I DA+M+D YFFRV
Sbjct: 61 FRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRV 120
Query: 121 ERGSYVRYNFMNDGFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFEECPPPSFSW 180
ERG V+Y++ + L+VTAL +KPD++ E LE G+P + C + E PP +FSW
Sbjct: 121 ERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSW 180
Query: 181 TGAALSSQGTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRD 240
TG ALS P T+ S L+ TPRP+DH T+LTC + V+ +RTV+L V+YAP+
Sbjct: 181 TGNALSP--LDPETTRSSELTLTPRPEDHGTNLTCQMKRQGAQVTTERTVQLNVSYAPQT 238
Query: 241 LVISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHP 300
+ I N ALE N YL +GQ LRLLC A S PPA LSW + L+++ P
Sbjct: 239 ITIF---RNGIALEILQ--NTSYLPVLEGQALRLLCDAPSNPPAHLSWFQGSPALNAT-P 292
Query: 301 WGPRPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENL 347
+ LEL V++ + G +TCRA++ LG Q L+LSV P+ L
Sbjct: 293 ISNTGI-LELRRVRSAEEGGFTCRAQHPLGFLQIFLNLSVYSLPQLL 338
>gi|148762980 sialic acid binding Ig-like lectin 14 [Homo sapiens]
Length = 396
Score = 273 bits (697), Expect = 5e-73
Identities = 155/341 (45%), Positives = 204/341 (59%), Gaps = 5/341 (1%)
Query: 2 LLPLLLSSLL-GGSQAMDGRFWIRVQESVMVPEGLCISVPCSFSYPRQDWTGSTPAYGYW 60
+LPLLL LL GGS + ++VQ+SV V EGLC+ VPCSFSYP + W S P Y YW
Sbjct: 1 MLPLLLLPLLWGGSLQEKPVYELQVQKSVTVQEGLCVLVPCSFSYPWRSWYSSPPLYVYW 60
Query: 61 FKAVTETTKGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFRV 120
F+ VATN+ R V+ T+GRF+L GD K NCSL I DA+M+D YFFRV
Sbjct: 61 FRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLGDVQKKNCSLSIGDARMEDTGSYFFRV 120
Query: 121 ERGSYVRYNFMNDGFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFEECPPPSFSW 180
ERG V+Y++ + L+VTAL +KPD++ E LE G+P + C + E PP +FSW
Sbjct: 121 ERGRDVKYSYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSW 180
Query: 181 TGAALSSQGTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRD 240
TG ALS P T+ S L+ TPRP+DH T+LTC V V+ +RTV+L V+YAP++
Sbjct: 181 TGNALSP--LDPETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQN 238
Query: 241 LVISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHP 300
L ISI N + N + Q+GQ L L C DS PPA+LSW + + L+ S
Sbjct: 239 LAISIFFRNGTGTALRILSNGMSVPIQEGQSLFLACTVDSNPPASLSWFREGKALNPSQT 298
Query: 301 WGPRPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQ 341
LELP + A + G +TCR ++ LGSQ + LSVQ
Sbjct: 299 --SMSGTLELPNIGAREGGEFTCRVQHPLGSQHLSFILSVQ 337
Score = 125 bits (314), Expect = 1e-28
Identities = 79/196 (40%), Positives = 105/196 (53%), Gaps = 13/196 (6%)
Query: 260 NVPYLEA-QKGQFLRLLCA----ADSQPPATLSWVLQNRVLSSSHPWGPRPLGLELPGVK 314
++ +LE + G+ RL C+ ++ PP T SW LS P R L L
Sbjct: 147 DIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWT--GNALSPLDPETTRSSELTLTPRP 204
Query: 315 AGDSGRYTCRAENRLGSQ---QRALDLSVQYPPENLRVMVSQANRT--VLENLGNGTSLP 369
TC+ + R G+Q +R + L+V Y P+NL + + N T L L NG S+P
Sbjct: 205 EDHGTNLTCQVK-RQGAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVP 263
Query: 370 VLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSDPGVLELPRVQVEHEGEFTCHARH 429
+ EGQSL L C S+PPA LSW + G+ L+PSQ S G LELP + GEFTC +H
Sbjct: 264 IQEGQSLFLACTVDSNPPASLSWFREGKALNPSQTSMSGTLELPNIGAREGGEFTCRVQH 323
Query: 430 PLGSQHVSLSLSVHYS 445
PLGSQH+S LSV S
Sbjct: 324 PLGSQHLSFILSVQRS 339
Score = 39.3 bits (90), Expect = 0.012
Identities = 57/218 (26%), Positives = 85/218 (38%), Gaps = 47/218 (21%)
Query: 308 LELPGVKAGDSGRYTCRAEN----RLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLG 363
L + + D+G Y R E + QQ L+L V ++ + + LE L
Sbjct: 103 LSIGDARMEDTGSYFFRVERGRDVKYSYQQNKLNLEVT-------ALIEKPDIHFLEPLE 155
Query: 364 NGTSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSDPGVLEL---PRVQVEHE 420
+G P SL C + PP SWT G LSP P EL PR + +H
Sbjct: 156 SGR--PTRLSCSLPGSC--EAGPPLTFSWT--GNALSPLDPETTRSSELTLTPRPE-DHG 208
Query: 421 GEFTCHARHPLGSQHVS---LSLSVHYSPKLLGPSCSW--------------------EA 457
TC + G+Q + + L+V Y+P+ L S + E
Sbjct: 209 TNLTCQVKRQ-GAQVTTERTVQLNVSYAPQNLAISIFFRNGTGTALRILSNGMSVPIQEG 267
Query: 458 EGLHCSCSSQASPAPSLRWWLGEELLEGNSSQDSFEVT 495
+ L +C+ ++P SL W+ + L N SQ S T
Sbjct: 268 QSLFLACTVDSNPPASLSWFREGKAL--NPSQTSMSGT 303
>gi|16506828 sialic acid binding immunoglobulin-like lectin-like
protein 1 isoform a precursor [Homo sapiens]
Length = 595
Score = 272 bits (696), Expect = 7e-73
Identities = 153/336 (45%), Positives = 199/336 (59%), Gaps = 9/336 (2%)
Query: 7 LSSLLGGSQAMDGRFWIRVQESVMVPEGLCISVPCSFSYPRQDWTGSTPAYGYWFKAVTE 66
LS + SQ + R+ + V ESV V EGLC+SVPCS YP +WT S+P YG WFK +
Sbjct: 137 LSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYNWTASSPVYGSWFKEGAD 196
Query: 67 TTKGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFRVERGSYV 126
PVATN S +V+ T GRF L GDP NCSL IRDA+ D +Y+F+VERGS
Sbjct: 197 IPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDARKGDSGKYYFQVERGSR- 255
Query: 127 RYNFMNDGFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFEECPPPSFSWTGAALS 186
++N++ D + VTALT P IP TLE G P + C WA E+ PP+ +W GA++S
Sbjct: 256 KWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPWACEQGTPPTITWMGASVS 315
Query: 187 SQGTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISIS 246
S PT + S+LS P+PQDH T LTC V GV+ R VRL ++Y P++L +++
Sbjct: 316 S--LDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVF 373
Query: 247 RDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPL 306
+ + A G+ L +GQ L L+CA DS PPA LSW + LS S L
Sbjct: 374 QGDGTASTTLRNGSA--LSVLEGQSLHLVCAVDSNPPARLSWTWGSLTLSPSQSSN---L 428
Query: 307 G-LELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQ 341
G LELP V D G +TCRA+N LGSQ +L LS+Q
Sbjct: 429 GVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQ 464
Score = 254 bits (648), Expect = 2e-67
Identities = 175/469 (37%), Positives = 247/469 (52%), Gaps = 38/469 (8%)
Query: 1 MLLPLLLSSLLGGSQAMDGRFWIRVQESVMVPEGLCISVPCSFSYPRQDWTGSTPAYGYW 60
+LLP LL +G + D + + +Q+SV V EGLC+SV CSFSYP+ WT S P +GYW
Sbjct: 6 LLLPPLLCGRVGAKEQKD--YLLTMQKSVTVQEGLCVSVLCSFSYPQNGWTASDPVHGYW 63
Query: 61 FKAVTETTKGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFRV 120
F+A ++ PVATN+ +R V+ TR RF L GDP +C+L IRD + D Y F V
Sbjct: 64 FRAGDHVSRNIPVATNNPARAVQEETRDRFHLLGDPQNKDCTLSIRDTRESDAGTYVFCV 123
Query: 121 ERGSYVRYNFMNDGFFLKVTA---LTQKPDVYIPE--TLEPGQPVTVICV-----FNWAF 170
ERG+ +++N+ D + VTA L + + +PE T++ G V+V C +NW
Sbjct: 124 ERGN-MKWNYKYDQLSVNVTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHYNWTA 182
Query: 171 EECPPPSFSWTGAAL-----------SSQGTKPTTSHFSVLSFTPRPQDHNTDLTCHVDF 219
S+ GA + S + + T F +L PQ +N L+ +
Sbjct: 183 SSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLG---DPQTNNCSLS--IRD 237
Query: 220 SRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLC--- 276
+RKG S + ++ + + + AL P ++P + G L C
Sbjct: 238 ARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGT-LESGHPRNLTCSVP 296
Query: 277 -AADSQPPATLSWVLQNRVLSSSHPWGPRPLGLELPGVKAGDSGRYTCRAE--NRLGSQQ 333
A + P T++W+ +SS P R L L TC+ +
Sbjct: 297 WACEQGTPPTITWM--GASVSSLDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMT 354
Query: 334 RALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPARLSWT 393
RA+ L++ YPP+NL + V Q + T L NG++L VLEGQSL LVC S+PPARLSWT
Sbjct: 355 RAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWT 414
Query: 394 QRGQVLSPSQPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSV 442
LSPSQ S+ GVLELPRV V+ EGEFTC A++PLGSQH+SLSLS+
Sbjct: 415 WGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSL 463
Score = 45.8 bits (107), Expect = 1e-04
Identities = 58/225 (25%), Positives = 91/225 (40%), Gaps = 30/225 (13%)
Query: 456 EAEGLHCSCSSQASPAPSLRWWLGEELLEGNSSQDSFEVTPSSAGPWANSSLSLHGGLSS 515
E + LH C+ ++P L W G S ++PS + L
Sbjct: 393 EGQSLHLVCAVDSNPPARLSWTWG-----------SLTLSPSQSSNLGVLELPRVHVKDE 441
Query: 516 GLRLRCEAWNVHGAQSGSI-LQLPDK---KGLISTAFSNGAFLGIGITALLFLCLALIIM 571
G C A N G+Q S+ L L ++ K + + GAF G G TAL+FL +I +
Sbjct: 442 G-EFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFV 500
Query: 572 KILPKRRTQTETPRPRFSRHSTILDYINVV---PTAGPLAQKRNQKATPNSPRTPLPPGA 628
+ R + ++ RP T ++ N V + GPL + + P+ P
Sbjct: 501 VV---RSCRKKSARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPH--HAPPALAT 555
Query: 629 PSPESKKNQKKQYQLPSFPEPKSSTQAPESQESQEELHYATLNFP 673
PSPE + + Q S K+ Q P+ QE+ Y+ +N P
Sbjct: 556 PSPE-----EGEIQYASLSFHKARPQYPQEQEA-IGYEYSEINIP 594
>gi|16506826 sialic acid binding immunoglobulin-like lectin-like
protein 1 isoform b precursor [Homo sapiens]
Length = 477
Score = 272 bits (695), Expect = 9e-73
Identities = 159/354 (44%), Positives = 206/354 (58%), Gaps = 21/354 (5%)
Query: 1 MLLPLLLSSL---LGG---------SQAMDGRFWIRVQESVMVPEGLCISVPCSFSYPRQ 48
MLLPLL ++ GG SQ + R+ + V ESV V EGLC+SVPCS YP
Sbjct: 1 MLLPLLWANEERDSGGWADPRFSTASQDLLSRYRLEVPESVTVQEGLCVSVPCSVLYPHY 60
Query: 49 DWTGSTPAYGYWFKAVTETTKGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDA 108
+WT S+P YG WFK + PVATN S +V+ T GRF L GDP NCSL IRDA
Sbjct: 61 NWTASSPVYGSWFKEGADIPWDIPVATNTPSGKVQEDTHGRFLLLGDPQTNNCSLSIRDA 120
Query: 109 QMQDESQYFFRVERGSYVRYNFMNDGFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNW 168
+ D +Y+F+VERGS ++N++ D + VTALT P IP TLE G P + C W
Sbjct: 121 RKGDSGKYYFQVERGSR-KWNYIYDKLSVHVTALTHMPTFSIPGTLESGHPRNLTCSVPW 179
Query: 169 AFEECPPPSFSWTGAALSSQGTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQR 228
A E+ PP+ +W GA++SS PT + S+LS P+PQDH T LTC V GV+ R
Sbjct: 180 ACEQGTPPTITWMGASVSS--LDPTITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTR 237
Query: 229 TVRLRVAYAPRDLVISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSW 288
VRL ++Y P++L +++ + + A G+ L +GQ L L+CA DS PPA LSW
Sbjct: 238 AVRLNISYPPQNLTMTVFQGDGTASTTLRNGSA--LSVLEGQSLHLVCAVDSNPPARLSW 295
Query: 289 VLQNRVLSSSHPWGPRPLG-LELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQ 341
+ LS S LG LELP V D G +TCRA+N LGSQ +L LS+Q
Sbjct: 296 TWGSLTLSPSQ---SSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLSLSLQ 346
Score = 137 bits (345), Expect = 3e-32
Identities = 94/243 (38%), Positives = 129/243 (53%), Gaps = 11/243 (4%)
Query: 206 PQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEPQPQGNVPYLE 265
PQ +N L+ + +RKG S + ++ + + + AL P ++P
Sbjct: 108 PQTNNCSLS--IRDARKGDSGKYYFQVERGSRKWNYIYDKLSVHVTALTHMPTFSIPGT- 164
Query: 266 AQKGQFLRLLC----AADSQPPATLSWVLQNRVLSSSHPWGPRPLGLELPGVKAGDSGRY 321
+ G L C A + P T++W+ +SS P R L L
Sbjct: 165 LESGHPRNLTCSVPWACEQGTPPTITWM--GASVSSLDPTITRSSMLSLIPQPQDHGTSL 222
Query: 322 TCRAE--NRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLV 379
TC+ + RA+ L++ YPP+NL + V Q + T L NG++L VLEGQSL LV
Sbjct: 223 TCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTASTTLRNGSALSVLEGQSLHLV 282
Query: 380 CVTHSSPPARLSWTQRGQVLSPSQPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLS 439
C S+PPARLSWT LSPSQ S+ GVLELPRV V+ EGEFTC A++PLGSQH+SLS
Sbjct: 283 CAVDSNPPARLSWTWGSLTLSPSQSSNLGVLELPRVHVKDEGEFTCRAQNPLGSQHISLS 342
Query: 440 LSV 442
LS+
Sbjct: 343 LSL 345
Score = 45.8 bits (107), Expect = 1e-04
Identities = 58/225 (25%), Positives = 91/225 (40%), Gaps = 30/225 (13%)
Query: 456 EAEGLHCSCSSQASPAPSLRWWLGEELLEGNSSQDSFEVTPSSAGPWANSSLSLHGGLSS 515
E + LH C+ ++P L W G S ++PS + L
Sbjct: 275 EGQSLHLVCAVDSNPPARLSWTWG-----------SLTLSPSQSSNLGVLELPRVHVKDE 323
Query: 516 GLRLRCEAWNVHGAQSGSI-LQLPDK---KGLISTAFSNGAFLGIGITALLFLCLALIIM 571
G C A N G+Q S+ L L ++ K + + GAF G G TAL+FL +I +
Sbjct: 324 G-EFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFLYFCIIFV 382
Query: 572 KILPKRRTQTETPRPRFSRHSTILDYINVV---PTAGPLAQKRNQKATPNSPRTPLPPGA 628
+ R + ++ RP T ++ N V + GPL + + P+ P
Sbjct: 383 VV---RSCRKKSARPAVGVGDTGMEDANAVRGSASQGPLIESPADDSPPH--HAPPALAT 437
Query: 629 PSPESKKNQKKQYQLPSFPEPKSSTQAPESQESQEELHYATLNFP 673
PSPE + + Q S K+ Q P+ QE+ Y+ +N P
Sbjct: 438 PSPE-----EGEIQYASLSFHKARPQYPQEQEA-IGYEYSEINIP 476
>gi|7657570 sialic acid binding Ig-like lectin 7 isoform 1 [Homo
sapiens]
Length = 467
Score = 271 bits (694), Expect = 1e-72
Identities = 149/346 (43%), Positives = 208/346 (60%), Gaps = 14/346 (4%)
Query: 2 LLPLLLSSLLGGSQAMDGR------FWIRVQESVMVPEGLCISVPCSFSYPRQDWTGSTP 55
+L LLL LL G + ++G+ + + +Q SV V EG+C+ V CSFSYP T S P
Sbjct: 1 MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDP 60
Query: 56 AYGYWFKAVTETTKGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQ 115
+GYWF+A + + APVATN+ + V+ TR RF L GDP NC+L IRDA+M D +
Sbjct: 61 VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGR 120
Query: 116 YFFRVERGSYVRYNFMNDGFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFEECPP 175
YFFR+E+G+ +++N+ D + VTALT +P++ IP TLE G + C WA E+ P
Sbjct: 121 YFFRMEKGN-IKWNYKYDQLSVNVTALTHRPNILIPGTLESGCFQNLTCSVPWACEQGTP 179
Query: 176 PSFSWTGAALSSQGTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVA 235
P SW G ++S P+T+ SVL+ P+PQ H T LTC V GV+ RT++L V+
Sbjct: 180 PMISWMGTSVSP--LHPSTTRSSVLTLIPQPQHHGTSLTCQVTLPGAGVTTNRTIQLNVS 237
Query: 236 YAPRDLVISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVL 295
Y P++L +++ + A GN L +GQ LRL+CA DS PPA LSW ++ L
Sbjct: 238 YPPQNLTVTVFQGEGTA--STALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTL 295
Query: 296 SSSHPWGPRPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQ 341
S P P L L+ V GD G +TCRA+N LGSQ +L+LS+Q
Sbjct: 296 YPSQPSNPLVLELQ---VHLGDEGEFTCRAQNSLGSQHVSLNLSLQ 338
Score = 129 bits (323), Expect = 1e-29
Identities = 87/200 (43%), Positives = 108/200 (54%), Gaps = 10/200 (5%)
Query: 249 NTPALEPQPQGNVPYLEAQKGQFLRLLC----AADSQPPATLSWVLQNRVLSSSHPWGPR 304
N AL +P +P + G F L C A + P +SW+ +S HP R
Sbjct: 142 NVTALTHRPNILIPGT-LESGCFQNLTCSVPWACEQGTPPMISWM--GTSVSPLHPSTTR 198
Query: 305 PLGLELPGVKAGDSGRYTCRAE--NRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENL 362
L L TC+ + R + L+V YPP+NL V V Q T L
Sbjct: 199 SSVLTLIPQPQHHGTSLTCQVTLPGAGVTTNRTIQLNVSYPPQNLTVTVFQGEGTASTAL 258
Query: 363 GNGTSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSDPGVLELPRVQVEHEGE 422
GN +SL VLEGQSL LVC S+PPARLSWT R L PSQPS+P VLEL +V + EGE
Sbjct: 259 GNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLYPSQPSNPLVLEL-QVHLGDEGE 317
Query: 423 FTCHARHPLGSQHVSLSLSV 442
FTC A++ LGSQHVSL+LS+
Sbjct: 318 FTCRAQNSLGSQHVSLNLSL 337
Score = 35.4 bits (80), Expect = 0.18
Identities = 96/416 (23%), Positives = 145/416 (34%), Gaps = 77/416 (18%)
Query: 287 SWVLQNRVLSSSHPWGP---RPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYP 343
+W +Q H G + L + + D+GRY R E ++ Y
Sbjct: 84 AWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRYFFRMEKG--------NIKWNYK 135
Query: 344 PENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSP-------PARLSWTQRG 396
+ L V N T L + N LE S C +T S P P +SW G
Sbjct: 136 YDQLSV-----NVTALTHRPNILIPGTLE--SGCFQNLTCSVPWACEQGTPPMISWM--G 186
Query: 397 QVLSPSQPSDP--GVLELPRVQVEHEGEFTCHARHPLG--SQHVSLSLSVHYSPK----- 447
+SP PS VL L H TC P + + ++ L+V Y P+
Sbjct: 187 TSVSPLHPSTTRSSVLTLIPQPQHHGTSLTCQVTLPGAGVTTNRTIQLNVSYPPQNLTVT 246
Query: 448 ----------LLGPSCSW---EAEGLHCSCSSQASPAPSLRWWLGEELLEGNSSQDSFEV 494
LG S S E + L C+ ++P L W + S +
Sbjct: 247 VFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSW-----------TWRSLTL 295
Query: 495 TPSSAGPWANSSLSLHGGLSSGLRLRCEAWNVHGAQSGSI-LQLPDK---KGLISTAFSN 550
PS L +H G C A N G+Q S+ L L + K +
Sbjct: 296 YPSQPSNPLVLELQVHLGDEG--EFTCRAQNSLGSQHVSLNLSLQQEYTGKMRPVSGVLL 353
Query: 551 GAFLGIGITALLFLCLALIIMKILPKRRTQTETPRPRFSRHSTILDYINVVPTAGPLAQK 610
GA G G TAL+FL +I + + R + ++ RP + N + +
Sbjct: 354 GAVGGAGATALVFLSFCVIFIVV---RSCRKKSARPAADVGDIGMKDANTIRGSASQGNL 410
Query: 611 RNQKATPNSPRTPLPPGAPSPESKKNQKKQYQLPSF----PEPKSSTQAPESQESQ 662
A N P G + S + ++ QY SF P+ S +A ++ S+
Sbjct: 411 TESWADDN----PRHHGLAAHSSGEEREIQYAPLSFHKGEPQDLSGQEATNNEYSE 462
>gi|23943856 sialic acid binding Ig-like lectin 9 [Homo sapiens]
Length = 463
Score = 262 bits (669), Expect = 9e-70
Identities = 159/384 (41%), Positives = 216/384 (56%), Gaps = 25/384 (6%)
Query: 5 LLLSSLLGGSQAMDGRF--WIRVQESVMVPEGLCISVPCSFSYPRQDWTGSTPA-YGYWF 61
LLL LL G + +G+ + +Q SV V EGLC+ VPCSFSYP W P +GYWF
Sbjct: 3 LLLLPLLWGRERAEGQTSKLLTMQSSVTVQEGLCVHVPCSFSYPSHGWIYPGPVVHGYWF 62
Query: 62 KAVTETTKGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFRVE 121
+ T + APVATN+ +R V TR RF L GDP NC+L IRDA+ D +YFFR+E
Sbjct: 63 REGANTDQDAPVATNNPARAVWEETRDRFHLLGDPHTKNCTLSIRDARRSDAGRYFFRME 122
Query: 122 RGSYVRYNFMNDGFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFEECPPPSFSWT 181
+GS +++N+ + + VTALT +P++ IP TLE G P + C WA E+ PP SW
Sbjct: 123 KGS-IKWNYKHHRLSVNVTALTHRPNILIPGTLESGCPQNLTCSVPWACEQGTPPMISWI 181
Query: 182 GAALSSQGTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDL 241
G ++S P+T+ SVL+ P+PQDH T LTC V F V+ +TV L V+Y P++L
Sbjct: 182 GTSVSP--LDPSTTRSSVLTLIPQPQDHGTSLTCQVTFPGASVTTNKTVHLNVSYPPQNL 239
Query: 242 VISISR-DNTPALEPQPQGNVPYLEAQKGQFLRLLC---AADSQPPATLSWVLQNRVLSS 297
+++ + D T + GN L +GQ LRL+C A DS PPA LS + L
Sbjct: 240 TMTVFQGDGTVS---TVLGNGSSLSLPEGQSLRLVCAVDAVDSNPPARLSLSWRGLTLCP 296
Query: 298 SHPWGPRPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRT 357
S P P LELP V D+ +TCRA+N LGSQQ L++S+Q S+A
Sbjct: 297 SQPSNPGV--LELPWVHLRDAAEFTCRAQNPLGSQQVYLNVSLQ----------SKATSG 344
Query: 358 VLENLGNGTSLPVLEGQSLCLVCV 381
V + + G L S C++ V
Sbjct: 345 VTQGVVGGAGATALVFLSFCVIFV 368
Score = 113 bits (283), Expect = 5e-25
Identities = 61/112 (54%), Positives = 78/112 (69%), Gaps = 3/112 (2%)
Query: 334 RALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTH---SSPPARL 390
+ + L+V YPP+NL + V Q + TV LGNG+SL + EGQSL LVC S+PPARL
Sbjct: 226 KTVHLNVSYPPQNLTMTVFQGDGTVSTVLGNGSSLSLPEGQSLRLVCAVDAVDSNPPARL 285
Query: 391 SWTQRGQVLSPSQPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSV 442
S + RG L PSQPS+PGVLELP V + EFTC A++PLGSQ V L++S+
Sbjct: 286 SLSWRGLTLCPSQPSNPGVLELPWVHLRDAAEFTCRAQNPLGSQQVYLNVSL 337
Score = 48.1 bits (113), Expect = 3e-05
Identities = 103/428 (24%), Positives = 155/428 (36%), Gaps = 111/428 (25%)
Query: 308 LELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTS 367
L + + D+GRY R E S+++ ++ R+ V N T L + N
Sbjct: 104 LSIRDARRSDAGRYFFRMEKG----------SIKWNYKHHRLSV---NVTALTHRPNILI 150
Query: 368 LPVLEGQSLCLVCVTHSSP-------PARLSWTQRGQVLSPSQPSDP--GVLELPRVQVE 418
LE S C +T S P P +SW G +SP PS VL L +
Sbjct: 151 PGTLE--SGCPQNLTCSVPWACEQGTPPMISWI--GTSVSPLDPSTTRSSVLTLIPQPQD 206
Query: 419 HEGEFTCHARHPLGS--QHVSLSLSVHYSPKLL-----------------GPSCSW-EAE 458
H TC P S + ++ L+V Y P+ L G S S E +
Sbjct: 207 HGTSLTCQVTFPGASVTTNKTVHLNVSYPPQNLTMTVFQGDGTVSTVLGNGSSLSLPEGQ 266
Query: 459 GLHCSCSSQA----SPAPSLRWWLGEELLEGNSSQDSFEVTPSSAG----PWANSSLSLH 510
L C+ A PA W G L PS+ G PW +
Sbjct: 267 SLRLVCAVDAVDSNPPARLSLSWRGLTLCPSQ---------PSNPGVLELPWVH------ 311
Query: 511 GGLSSGLRLRCEAWNVHGAQSGSILQLPDKKGLISTAFSNGAFLGIGITALLFLCLALII 570
L C A N G+Q + K ++ + G G G TAL+FL +I
Sbjct: 312 --LRDAAEFTCRAQNPLGSQQVYLNVSLQSKA--TSGVTQGVVGGAGATALVFLSFCVIF 367
Query: 571 MKILPKRRTQTETPRPRFSRHSTILDYINVV---PTAGPLAQKRNQKATPNSPRTPLPPG 627
+ + R + ++ RP T ++ N V + GPL + + + PP
Sbjct: 368 VVV---RSCRKKSARPAAGVGDTGIEDANAVRGSASQGPLTEPWAEDS---------PPD 415
Query: 628 APSPESKKNQKKQYQLPSFPEPKSSTQAPESQESQEELHYATLNFPGVRPRPEARMPKGT 687
P P S + S + EL YA+L+F V+P ++R + T
Sbjct: 416 QPPPASAR----------------------SSVGEGELQYASLSFQMVKPW-DSRGQEAT 452
Query: 688 QADYAEVK 695
+Y+E+K
Sbjct: 453 DTEYSEIK 460
>gi|193794821 sialic acid binding Ig-like lectin 6 isoform 1
precursor [Homo sapiens]
Length = 453
Score = 257 bits (656), Expect = 3e-68
Identities = 151/349 (43%), Positives = 205/349 (58%), Gaps = 24/349 (6%)
Query: 2 LLPLLLSSLLGGSQAMDGRFWIRVQESVMVPEGLCISVPCSFSYPRQDWTGSTPAYGYWF 61
+LPLLL L G+ A + RF + ES+ V EGLC+ VPC S YGYWF
Sbjct: 12 MLPLLLPLLWAGALAQERRFQLEGPESLTVQEGLCVLVPCRLP---TTLPASYYGYGYWF 68
Query: 62 KAVTETTKGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFRVE 121
+ PVATN EV+ TRGRF L DP + NCSL IRDA+ +D + YFFR+
Sbjct: 69 LEGADV----PVATNDPDEEVQEETRGRFHLLWDPRRKNCSLSIRDARRRDNAAYFFRL- 123
Query: 122 RGSYVRYNFMNDGFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFEECPPPSFSWT 181
+ +++Y + + ++V ALT +P++ IP TLE G P + C W E+ PP FSW
Sbjct: 124 KSKWMKYGYTSSKLSVRVMALTHRPNISIPGTLESGHPSNLTCSVPWVCEQGTPPIFSWM 183
Query: 182 GAALSSQGTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDL 241
AA +S G P T+ SVL+ TPRPQDH+T+LTC V F GV+ +RT++L V+YAP+ +
Sbjct: 184 SAAPTSLG--PRTTQSSVLTITPRPQDHSTNLTCQVTFPGAGVTMERTIQLNVSYAPQKV 241
Query: 242 VISISRDNTPALE-PQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHP 300
ISI + N+ A + Q ++P LE GQ LRLLC AD PPA LSW L+++
Sbjct: 242 AISIFQGNSAAFKILQNTSSLPVLE---GQALRLLCDADGNPPAHLSWFQGFPALNAT-- 296
Query: 301 WGPRPLG----LELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPE 345
P+ LELP V + + G +TCRA++ LGS Q +L L V + PE
Sbjct: 297 ----PISNTGVLELPQVGSAEEGDFTCRAQHPLGSLQISLSLFVHWKPE 341
Score = 111 bits (277), Expect = 3e-24
Identities = 54/117 (46%), Positives = 76/117 (64%)
Query: 331 SQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPARL 390
+ +R + L+V Y P+ + + + Q N + L N +SLPVLEGQ+L L+C +PPA L
Sbjct: 225 TMERTIQLNVSYAPQKVAISIFQGNSAAFKILQNTSSLPVLEGQALRLLCDADGNPPAHL 284
Query: 391 SWTQRGQVLSPSQPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHYSPK 447
SW Q L+ + S+ GVLELP+V EG+FTC A+HPLGS +SLSL VH+ P+
Sbjct: 285 SWFQGFPALNATPISNTGVLELPQVGSAEEGDFTCRAQHPLGSLQISLSLFVHWKPE 341
Score = 47.4 bits (111), Expect = 5e-05
Identities = 68/340 (20%), Positives = 114/340 (33%), Gaps = 85/340 (25%)
Query: 381 VTHSSPPARLSWTQRGQVLSPSQPSDPGVLELPRVQVEHEGEFTCHARHPLG--SQHVSL 438
V P SW + + VL + +H TC P + ++
Sbjct: 171 VCEQGTPPIFSWMSAAPTSLGPRTTQSSVLTITPRPQDHSTNLTCQVTFPGAGVTMERTI 230
Query: 439 SLSVHYSPKLL------GPSCSW------------EAEGLHCSCSSQASPAPSLRWWLGE 480
L+V Y+P+ + G S ++ E + L C + +P L W+ G
Sbjct: 231 QLNVSYAPQKVAISIFQGNSAAFKILQNTSSLPVLEGQALRLLCDADGNPPAHLSWFQGF 290
Query: 481 ELLEGNSSQDSF-----EVTPSSAGPWANSSLSLHGGLSSGLRLRCEAWNVHGAQSGSIL 535
L ++ +V + G + + G L L L W G G +
Sbjct: 291 PALNATPISNTGVLELPQVGSAEEGDFTCRAQHPLGSLQISLSLFVH-WKPEGRAGGVL- 348
Query: 536 QLPDKKGLISTAFSNGAFLGIGITALLFLCLALIIMKILPKRRTQTETPRPRFSRHSTIL 595
GA G IT L+FLC+ I + +T R + ++
Sbjct: 349 ---------------GAVWGASITTLVFLCVCFIF---------RVKTRRKKAAQPVQNT 384
Query: 596 DYINVVPTAGPLAQKRNQKATPNSPRTPLPPGAPSPESKKNQKKQYQLPSFPEPKSSTQA 655
D +N V +G ++ Q+Q + +A
Sbjct: 385 DDVNPVMVSG------------------------------SRGHQHQFQTGIVSDHPAEA 414
Query: 656 PESQESQEELHYATLNFPGVRPRPEARMPKGTQADYAEVK 695
E ++ELHYA L+F V+P+ PK T +Y+E+K
Sbjct: 415 GPISEDEQELHYAVLHFHKVQPQE----PKVTDTEYSEIK 450
>gi|193794817 sialic acid binding Ig-like lectin 6 isoform 3
precursor [Homo sapiens]
Length = 353
Score = 253 bits (645), Expect = 5e-67
Identities = 149/346 (43%), Positives = 203/346 (58%), Gaps = 24/346 (6%)
Query: 2 LLPLLLSSLLGGSQAMDGRFWIRVQESVMVPEGLCISVPCSFSYPRQDWTGSTPAYGYWF 61
+LPLLL L G+ A + RF + ES+ V EGLC+ VPC S YGYWF
Sbjct: 12 MLPLLLPLLWAGALAQERRFQLEGPESLTVQEGLCVLVPCRLP---TTLPASYYGYGYWF 68
Query: 62 KAVTETTKGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFRVE 121
+ PVATN EV+ TRGRF L DP + NCSL IRDA+ +D + YFFR+
Sbjct: 69 LEGADV----PVATNDPDEEVQEETRGRFHLLWDPRRKNCSLSIRDARRRDNAAYFFRL- 123
Query: 122 RGSYVRYNFMNDGFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFEECPPPSFSWT 181
+ +++Y + + ++V ALT +P++ IP TLE G P + C W E+ PP FSW
Sbjct: 124 KSKWMKYGYTSSKLSVRVMALTHRPNISIPGTLESGHPSNLTCSVPWVCEQGTPPIFSWM 183
Query: 182 GAALSSQGTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDL 241
AA +S G P T+ SVL+ TPRPQDH+T+LTC V F GV+ +RT++L V+YAP+ +
Sbjct: 184 SAAPTSLG--PRTTQSSVLTITPRPQDHSTNLTCQVTFPGAGVTMERTIQLNVSYAPQKV 241
Query: 242 VISISRDNTPALE-PQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHP 300
ISI + N+ A + Q ++P LE GQ LRLLC AD PPA LSW L+++
Sbjct: 242 AISIFQGNSAAFKILQNTSSLPVLE---GQALRLLCDADGNPPAHLSWFQGFPALNAT-- 296
Query: 301 WGPRPLG----LELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQY 342
P+ LELP V + + G +TCRA++ LGS Q +L L V +
Sbjct: 297 ----PISNTGVLELPQVGSAEEGDFTCRAQHPLGSLQISLSLFVHW 338
Score = 109 bits (273), Expect = 8e-24
Identities = 54/115 (46%), Positives = 75/115 (65%)
Query: 331 SQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPARL 390
+ +R + L+V Y P+ + + + Q N + L N +SLPVLEGQ+L L+C +PPA L
Sbjct: 225 TMERTIQLNVSYAPQKVAISIFQGNSAAFKILQNTSSLPVLEGQALRLLCDADGNPPAHL 284
Query: 391 SWTQRGQVLSPSQPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHYS 445
SW Q L+ + S+ GVLELP+V EG+FTC A+HPLGS +SLSL VH+S
Sbjct: 285 SWFQGFPALNATPISNTGVLELPQVGSAEEGDFTCRAQHPLGSLQISLSLFVHWS 339
>gi|193794819 sialic acid binding Ig-like lectin 6 isoform 2
precursor [Homo sapiens]
Length = 437
Score = 235 bits (599), Expect = 1e-61
Identities = 143/348 (41%), Positives = 192/348 (55%), Gaps = 38/348 (10%)
Query: 2 LLPLLLSSLLGGSQAMDGRFWIRVQESVMVPEGLCISVPCSFSYPRQDWTGSTPAYGYWF 61
+LPLLL L G+ A + RF + ES+ V EGLC+ VPC S YGYWF
Sbjct: 12 MLPLLLPLLWAGALAQERRFQLEGPESLTVQEGLCVLVPCRLP---TTLPASYYGYGYWF 68
Query: 62 KAVTETTKGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFRVE 121
+ PVATN EV+ TRGRF L DP + NCSL IRDA+ +D + YFFR+
Sbjct: 69 LEGADV----PVATNDPDEEVQEETRGRFHLLWDPRRKNCSLSIRDARRRDNAAYFFRL- 123
Query: 122 RGSYVRYNFMNDGFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFEECPPPSFSWT 181
+ +++Y + + ++V ALT +P++ IP TLE G P + C W E+ PP FSW
Sbjct: 124 KSKWMKYGYTSSKLSVRVMALTHRPNISIPGTLESGHPSNLTCSVPWVCEQGTPPIFSWM 183
Query: 182 GAALSSQGTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDL 241
AA +S G P T+ SVL+ TPRPQDH+T+LTC V F GV+ +RT++L V+
Sbjct: 184 SAAPTSLG--PRTTQSSVLTITPRPQDHSTNLTCQVTFPGAGVTMERTIQLNVS----SF 237
Query: 242 VISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPW 301
I + + P LE GQ LRLLC AD PPA LSW L+++
Sbjct: 238 KILQNTSSLPVLE--------------GQALRLLCDADGNPPAHLSWFQGFPALNAT--- 280
Query: 302 GPRPLG----LELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPE 345
P+ LELP V + + G +TCRA++ LGS Q +L L V + PE
Sbjct: 281 ---PISNTGVLELPQVGSAEEGDFTCRAQHPLGSLQISLSLFVHWKPE 325
Score = 95.5 bits (236), Expect = 1e-19
Identities = 49/95 (51%), Positives = 64/95 (67%)
Query: 353 QANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSDPGVLEL 412
Q N + + L N +SLPVLEGQ+L L+C +PPA LSW Q L+ + S+ GVLEL
Sbjct: 231 QLNVSSFKILQNTSSLPVLEGQALRLLCDADGNPPAHLSWFQGFPALNATPISNTGVLEL 290
Query: 413 PRVQVEHEGEFTCHARHPLGSQHVSLSLSVHYSPK 447
P+V EG+FTC A+HPLGS +SLSL VH+ P+
Sbjct: 291 PQVGSAEEGDFTCRAQHPLGSLQISLSLFVHWKPE 325
Score = 48.9 bits (115), Expect = 2e-05
Identities = 66/324 (20%), Positives = 110/324 (33%), Gaps = 69/324 (21%)
Query: 381 VTHSSPPARLSWTQRGQVLSPSQPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSL 440
V P SW + + VL + +H TC P + ++
Sbjct: 171 VCEQGTPPIFSWMSAAPTSLGPRTTQSSVLTITPRPQDHSTNLTCQVTFPGAGVTMERTI 230
Query: 441 SVHYSP-KLLGPSCSW---EAEGLHCSCSSQASPAPSLRWWLGEELLEGNSSQDSF---- 492
++ S K+L + S E + L C + +P L W+ G L ++
Sbjct: 231 QLNVSSFKILQNTSSLPVLEGQALRLLCDADGNPPAHLSWFQGFPALNATPISNTGVLEL 290
Query: 493 -EVTPSSAGPWANSSLSLHGGLSSGLRLRCEAWNVHGAQSGSILQLPDKKGLISTAFSNG 551
+V + G + + G L L L W G G + G
Sbjct: 291 PQVGSAEEGDFTCRAQHPLGSLQISLSLFVH-WKPEGRAGGVL----------------G 333
Query: 552 AFLGIGITALLFLCLALIIMKILPKRRTQTETPRPRFSRHSTILDYINVVPTAGPLAQKR 611
A G IT L+FLC+ I + +T R + ++ D +N V +G
Sbjct: 334 AVWGASITTLVFLCVCFIF---------RVKTRRKKAAQPVQNTDDVNPVMVSG------ 378
Query: 612 NQKATPNSPRTPLPPGAPSPESKKNQKKQYQLPSFPEPKSSTQAPESQESQEELHYATLN 671
++ Q+Q + +A E ++ELHYA L+
Sbjct: 379 ------------------------SRGHQHQFQTGIVSDHPAEAGPISEDEQELHYAVLH 414
Query: 672 FPGVRPRPEARMPKGTQADYAEVK 695
F V+P+ PK T +Y+E+K
Sbjct: 415 FHKVQPQE----PKVTDTEYSEIK 434
>gi|130979981 CD33 antigen isoform 1 precursor [Homo sapiens]
Length = 364
Score = 233 bits (595), Expect = 3e-61
Identities = 116/240 (48%), Positives = 159/240 (66%), Gaps = 3/240 (1%)
Query: 1 MLLPLLLSSLLGGSQAMDGRFWIRVQESVMVPEGLCISVPCSFSYPRQDWTGSTPAYGYW 60
M L LLL L G+ AMD FW++VQESV V EGLC+ VPC+F +P + ++P +GYW
Sbjct: 1 MPLLLLLPLLWAGALAMDPNFWLQVQESVTVQEGLCVLVPCTFFHPIPYYDKNSPVHGYW 60
Query: 61 FKAVTETTKGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFRV 120
F+ ++ +PVATN +EV+ T+GRF+L GDP++ NCSL I DA+ +D YFFR+
Sbjct: 61 FREGAIISRDSPVATNKLDQEVQEETQGRFRLLGDPSRNNCSLSIVDARRRDNGSYFFRM 120
Query: 121 ERGSYVRYNFMNDGFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFEECPPPSFSW 180
ERGS +Y++ + + VT LT +P + IP TLEPG + C +WA E+ PP FSW
Sbjct: 121 ERGS-TKYSYKSPQLSVHVTDLTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSW 179
Query: 181 TGAALSSQGTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRD 240
AA +S G P T+H SVL TPRPQDH T+LTC V F+ GV+ +RT++L V Y P++
Sbjct: 180 LSAAPTSLG--PRTTHSSVLIITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQN 237
Score = 56.2 bits (134), Expect = 1e-07
Identities = 45/148 (30%), Positives = 59/148 (39%), Gaps = 42/148 (28%)
Query: 550 NGAFLGIGITALLFLCLALIIMKILPKRRTQTETPRPRFSRHSTILDYINVVPTAGPLAQ 609
+GA G G+TALL LCL LI + RR T R H PT G +
Sbjct: 259 HGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTH----------PTTGSASP 308
Query: 610 KRNQKATPNSPRTPLPPGAPSPESKKNQKKQYQLPSFPEPKSSTQAPESQESQEELHYAT 669
K +K+ + P E S + A + E EELHYA+
Sbjct: 309 KHQKKSKLHGPT--------------------------ETSSCSGAAPTVEMDEELHYAS 342
Query: 670 LNFPGVRPRPEARMPKGTQADYAEVKFQ 697
LNF G+ P K T +Y+EV+ Q
Sbjct: 343 LNFHGMNP------SKDTSTEYSEVRTQ 364
>gi|11225258 myelin associated glycoprotein isoform a precursor
[Homo sapiens]
Length = 626
Score = 190 bits (483), Expect = 3e-48
Identities = 164/587 (27%), Positives = 256/587 (43%), Gaps = 63/587 (10%)
Query: 14 SQAMDGRFWIRVQESVMVPEGLCISVPCSFSYPRQDWTGSTPAYGYWFKAVTETTKGAPV 73
S + G + + S+ EG C+S+PC F +P D +G W+ PV
Sbjct: 15 SASRGGHWGAWMPSSISAFEGTCVSIPCRFDFP--DELRPAVVHGVWYFNSPYPKNYPPV 72
Query: 74 ATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFRVERGSYVRYNFMND 133
+++ V S +GR +L GD NC+L++ + + +Y+FR + G Y +Y F
Sbjct: 73 VFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSNVSPELGGKYYFRGDLGGYNQYTFSEH 132
Query: 134 GFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFEECPP--PSFSWTG-------AA 184
V + P++ +P + G V V C+ + CP P SW G A
Sbjct: 133 ----SVLDIVNTPNIVVPPEVVAGTEVEVSCMVP---DNCPELRPELSWLGHEGLGEPAV 185
Query: 185 LSS-QGTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDLVI 243
L + + T S+L F P + + L C F + + + V Y P + +
Sbjct: 186 LGRLREDEGTWVQVSLLHFVPTREANGHRLGCQASFPNTTLQFEGYASMDVKYPPVIVEM 245
Query: 244 SISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGP 303
+ S +EA +G + LLC ADS PP L+W+ VL +
Sbjct: 246 NSS-----------------VEAIEGSHVSLLCGADSNPPPLLTWMRDGTVLREA---VA 285
Query: 304 RPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLG 363
L LEL V + G Y C AEN G R + LSV Y P V
Sbjct: 286 ESLLLELEEVTPAEDGVYACLAENAYGQDNRTVGLSVMYAPWKPTV-------------- 331
Query: 364 NGTSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSDPGVLELPRVQVEHEGEF 423
NGT + V EG+++ ++C T S+P L+ + Q+LS LELP V E +GE+
Sbjct: 332 NGTMVAV-EGETVSILCSTQSNPDPILTIFKEKQILSTVIYESELQLELPAVSPEDDGEY 390
Query: 424 TCHARHPLGSQHVSLSLSVHYSPKLLGPS-CSWEAEGLHCSCSSQASPAPSLRWWLGEEL 482
C A + G + + +LSV ++P LL S C+ + + C C +++P PS+ + L
Sbjct: 391 WCVAENQYGQRATAFNLSVEFAPVLLLESHCAAARDTVQCLCVVKSNPEPSVAFELPSRN 450
Query: 483 LEGNSSQDSFEVTPSSAGPWANSSLSLHGGLSSGLRLRCEAWNVHGAQSGSILQLPDKKG 542
+ N S+ F V +G S L+L G + R+ C A N++GA+S L+LP +G
Sbjct: 451 VTVNESEREF-VYSERSGLVLTSILTLRGQAQAPPRVICTARNLYGAKS---LELP-FQG 505
Query: 543 LISTAFSNGAFLGIGITALLFLCLALIIMKILPKRRTQTETPRPRFS 589
++ +G + F L I+ I RR + T P FS
Sbjct: 506 AHRLMWAKIGPVG---AVVAFAILIAIVCYITQTRRKKNVTESPSFS 549
>gi|18104957 myelin associated glycoprotein isoform b precursor
[Homo sapiens]
Length = 582
Score = 190 bits (483), Expect = 3e-48
Identities = 164/587 (27%), Positives = 256/587 (43%), Gaps = 63/587 (10%)
Query: 14 SQAMDGRFWIRVQESVMVPEGLCISVPCSFSYPRQDWTGSTPAYGYWFKAVTETTKGAPV 73
S + G + + S+ EG C+S+PC F +P D +G W+ PV
Sbjct: 15 SASRGGHWGAWMPSSISAFEGTCVSIPCRFDFP--DELRPAVVHGVWYFNSPYPKNYPPV 72
Query: 74 ATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFRVERGSYVRYNFMND 133
+++ V S +GR +L GD NC+L++ + + +Y+FR + G Y +Y F
Sbjct: 73 VFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSNVSPELGGKYYFRGDLGGYNQYTFSEH 132
Query: 134 GFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFEECPP--PSFSWTG-------AA 184
V + P++ +P + G V V C+ + CP P SW G A
Sbjct: 133 ----SVLDIVNTPNIVVPPEVVAGTEVEVSCMVP---DNCPELRPELSWLGHEGLGEPAV 185
Query: 185 LSS-QGTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDLVI 243
L + + T S+L F P + + L C F + + + V Y P + +
Sbjct: 186 LGRLREDEGTWVQVSLLHFVPTREANGHRLGCQASFPNTTLQFEGYASMDVKYPPVIVEM 245
Query: 244 SISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGP 303
+ S +EA +G + LLC ADS PP L+W+ VL +
Sbjct: 246 NSS-----------------VEAIEGSHVSLLCGADSNPPPLLTWMRDGTVLREA---VA 285
Query: 304 RPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLG 363
L LEL V + G Y C AEN G R + LSV Y P V
Sbjct: 286 ESLLLELEEVTPAEDGVYACLAENAYGQDNRTVGLSVMYAPWKPTV-------------- 331
Query: 364 NGTSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSDPGVLELPRVQVEHEGEF 423
NGT + V EG+++ ++C T S+P L+ + Q+LS LELP V E +GE+
Sbjct: 332 NGTMVAV-EGETVSILCSTQSNPDPILTIFKEKQILSTVIYESELQLELPAVSPEDDGEY 390
Query: 424 TCHARHPLGSQHVSLSLSVHYSPKLLGPS-CSWEAEGLHCSCSSQASPAPSLRWWLGEEL 482
C A + G + + +LSV ++P LL S C+ + + C C +++P PS+ + L
Sbjct: 391 WCVAENQYGQRATAFNLSVEFAPVLLLESHCAAARDTVQCLCVVKSNPEPSVAFELPSRN 450
Query: 483 LEGNSSQDSFEVTPSSAGPWANSSLSLHGGLSSGLRLRCEAWNVHGAQSGSILQLPDKKG 542
+ N S+ F V +G S L+L G + R+ C A N++GA+S L+LP +G
Sbjct: 451 VTVNESEREF-VYSERSGLVLTSILTLRGQAQAPPRVICTARNLYGAKS---LELP-FQG 505
Query: 543 LISTAFSNGAFLGIGITALLFLCLALIIMKILPKRRTQTETPRPRFS 589
++ +G + F L I+ I RR + T P FS
Sbjct: 506 AHRLMWAKIGPVG---AVVAFAILIAIVCYITQTRRKKNVTESPSFS 549
>gi|118197279 sialic acid binding Ig-like lectin 7 isoform 2 [Homo
sapiens]
Length = 374
Score = 130 bits (328), Expect = 3e-30
Identities = 77/213 (36%), Positives = 118/213 (55%), Gaps = 26/213 (12%)
Query: 2 LLPLLLSSLLGGSQAMDGR------FWIRVQESVMVPEGLCISVPCSFSYPRQDWTGSTP 55
+L LLL LL G + ++G+ + + +Q SV V EG+C+ V CSFSYP T S P
Sbjct: 1 MLLLLLLPLLWGRERVEGQKSNRKDYSLTMQSSVTVQEGMCVHVRCSFSYPVDSQTDSDP 60
Query: 56 AYGYWFKAVTETTKGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQ 115
+GYWF+A + + APVATN+ + V+ TR RF L GDP NC+L IRDA+M D +
Sbjct: 61 VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGR 120
Query: 116 YFFRVERGSYVRYNFMNDGFFLKVTALTQKPDVYIPE---------------TLEPGQPV 160
YFFR+E+G+ +++N+ D + VT Q V + + ++ GQ +
Sbjct: 121 YFFRMEKGN-IKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSL 179
Query: 161 TVICVFNWAFEECPPPSFSWTGAALSSQGTKPT 193
++C A + PP SWT +L+ ++P+
Sbjct: 180 RLVC----AVDSNPPARLSWTWRSLTLYPSQPS 208
Score = 124 bits (311), Expect = 3e-28
Identities = 75/162 (46%), Positives = 95/162 (58%), Gaps = 7/162 (4%)
Query: 287 SWVLQNRVLSSSHPWGP---RPLGLELPGVKAGDSGRYTCRAEN---RLGSQQRALDLSV 340
+W +Q H G + L + + D+GRY R E + + L ++V
Sbjct: 84 AWAVQEETRDRFHLLGDPQTKNCTLSIRDARMSDAGRYFFRMEKGNIKWNYKYDQLSVNV 143
Query: 341 QYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLS 400
PP+NL V V Q T LGN +SL VLEGQSL LVC S+PPARLSWT R L
Sbjct: 144 TDPPQNLTVTVFQGEGTASTALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWRSLTLY 203
Query: 401 PSQPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSV 442
PSQPS+P VLEL +V + EGEFTC A++ LGSQHVSL+LS+
Sbjct: 204 PSQPSNPLVLEL-QVHLGDEGEFTCRAQNSLGSQHVSLNLSL 244
Score = 76.6 bits (187), Expect = 7e-14
Identities = 45/110 (40%), Positives = 62/110 (56%), Gaps = 5/110 (4%)
Query: 232 LRVAYAPRDLVISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQ 291
+ V P++L +++ + A GN L +GQ LRL+CA DS PPA LSW +
Sbjct: 141 VNVTDPPQNLTVTVFQGEGTA--STALGNSSSLSVLEGQSLRLVCAVDSNPPARLSWTWR 198
Query: 292 NRVLSSSHPWGPRPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQ 341
+ L S P P L L+ V GD G +TCRA+N LGSQ +L+LS+Q
Sbjct: 199 SLTLYPSQPSNPLVLELQ---VHLGDEGEFTCRAQNSLGSQHVSLNLSLQ 245
>gi|13489095 sialoadhesin precursor [Homo sapiens]
Length = 1709
Score = 108 bits (269), Expect = 2e-23
Identities = 131/524 (25%), Positives = 215/524 (41%), Gaps = 74/524 (14%)
Query: 5 LLLSSLLGGSQAMDGRFWIRVQESVMVPEGLCISVPCSFSYPRQDWT--GSTPAYGYWFK 62
LLL+S QA G + + V +G C+ +PC FS+P G T + Y +
Sbjct: 8 LLLASFFPAGQASWG---VSSPQDVQGVKGSCLLIPCIFSFPADVEVPDGITAIWYYDYS 64
Query: 63 AVTETTKGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFRVER 122
+ V+ + + VE RGR + G+P C+L+++D Q +D Y FR E
Sbjct: 65 GQRQV-----VSHSADPKLVEARFRGRTEFMGNPEHRVCNLLLKDLQPEDSGSYNFRFEI 119
Query: 123 GSYVRYNFMNDGFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFEECPPPSFSWTG 182
R++ + G + VT + P + P L G V C + + W G
Sbjct: 120 SEVNRWSDVK-GTLVTVTEEPRVPTIASPVELLEGTEVDFNCSTPYVCLQ-EQVRLQWQG 177
Query: 183 ------AALSSQGTKPT-TSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVA 235
+SQ +PT H L QDH L C + + AQ + L+V
Sbjct: 178 QDPARSVTFNSQKFEPTGVGHLETLHMAMSWQDHGRILRCQLSVANH--RAQSEIHLQVK 235
Query: 236 YAPRDLVISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPA--TLSWVLQNR 293
YAP+ + I +S P + +P G+ + L C +S PA ++ W+
Sbjct: 236 YAPKGVKILLS--------PSGRNILP------GELVTLTCQVNSSYPAVSSIKWLKDGV 281
Query: 294 VLSSSHPWGPRPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQ 353
L + + L LP D+G YTC+AEN +G S+ PP +L + +++
Sbjct: 282 RLQT------KTGVLHLPQAAWSDAGVYTCQAENGVG--------SLVSPPISLHIFMAE 327
Query: 354 ANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPA--RLSWTQRGQVLSPSQPSDPGVLE 411
+ + P+LE Q++ LVC T + P+ R SW + +L + + L
Sbjct: 328 VQVS--------PAGPILENQTVTLVCNTPNEAPSDLRYSWYKNHVLL---EDAHSHTLR 376
Query: 412 LPRVQVEHEGEFTCHARHPLGSQHVS-LSLSVHYSPKLLGPSCSWEAEG-----LHCSCS 465
L G + C ++ GS+ +S+ V++ P + E + LHCS
Sbjct: 377 LHLATRADTGFYFCEVQNVHGSERSGPVSVVVNHPPLTPVLTAFLETQAGLVGILHCSVV 436
Query: 466 SQASPAPSLRWWLGEELLEGNSSQDSFEVTPSSAGPWANSSLSL 509
S+ P +L G +L S + +P +G +SL L
Sbjct: 437 SE--PLATLVLSHGGHILASTSGDS--DHSPRFSGTSGPNSLRL 476
Score = 80.5 bits (197), Expect = 5e-15
Identities = 77/265 (29%), Positives = 116/265 (43%), Gaps = 33/265 (12%)
Query: 262 PYLEAQKGQFLRLLCAADSQPPA--TLSWVLQNRVLSSSHPWGPRPLGLELPGVKAGDSG 319
P ++GQ + L C + PA T +W + +H + LP V D+
Sbjct: 1093 PGATVREGQLVNLTCLVWTTHPAQLTYTWYQDGQQRLDAH-------SIPLPNVTVRDAT 1145
Query: 320 RYTCRA--ENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLC 377
Y C R R + L V Y P NLR+ +LE+ G GQ
Sbjct: 1146 SYRCGVGPPGRAPRLSRPITLDVLYAPRNLRLTY------LLESHG---------GQLAL 1190
Query: 378 LVCVTHSSPPARLSWTQRGQVLSPSQPSD-PGVL--ELPRVQVEHEGEFTCHARHPLGSQ 434
++C S PPA+L+ + G++L+ S + P L EL Q EG ++C AR PLG
Sbjct: 1191 VLCTVDSRPPAQLALSHAGRLLASSTAASVPNTLRLELRGPQPRDEGFYSCSARSPLGQA 1250
Query: 435 HVSLSLSVHYSPKLLGPSCSW-EAEGLHCSCSSQASPAPSLRWWL--GEELLEGNSSQDS 491
+ SL L + +L P + E + +C+ A+ AP+L W G L EG ++ S
Sbjct: 1251 NTSLELRLEGVRVILAPEAAVPEGAPITVTCADPAAHAPTLYTWYHNGRWLQEGPAASLS 1310
Query: 492 FEV-TPSSAGPWANSSLSLHGGLSS 515
F V T + AG ++ + G SS
Sbjct: 1311 FLVATRAHAGAYSCQAQDAQGTRSS 1335
Score = 73.2 bits (178), Expect = 8e-13
Identities = 111/475 (23%), Positives = 176/475 (37%), Gaps = 85/475 (17%)
Query: 83 EMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFRVERGSYVRYNFMNDGFFLKVTAL 142
++ + GRFQ + + L +R+ + D Y R E + + + + F ++ +
Sbjct: 843 QVPSHGRFQAKAEA--NSLKLEVRELGLGDSGSY--RCEATNVLGSSNTSLFFQVRGAWV 898
Query: 143 TQKPDVYIPETLEPGQPVTVICVFNWAFEECPPPSFSWTGAALSSQGTKPTTSHFSVLSF 202
P PE L+ GQ V + C + E S+ W Q + T F+ ++
Sbjct: 899 QVSPS---PE-LQEGQAVVLSCQVHTGVPE--GTSYRWYRDGQPLQESTSATLRFAAITL 952
Query: 203 TPRPQDHNTDLTCHVDFSRKGV-SAQRTVRLRVAYAPRDLVISISRDNTPALEPQPQGNV 261
T H C S + L V+YAPR + ++ D P
Sbjct: 953 TQAGAYH-----CQAQAPGSATTSLAAPISLHVSYAPRHVTLTTLMDTGP---------- 997
Query: 262 PYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSS-----HPWG----------PRPL 306
G+ LLC DS PPA L + +R+++S+ P G P L
Sbjct: 998 -------GRLGLLLCRVDSDPPAQLRLLHGDRLVASTLQGVGGPEGSSPRLHVAVAPNTL 1050
Query: 307 GLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGT 366
LE+ G D G Y C A N LG + D Q N+
Sbjct: 1051 RLEIHGAMLEDEGVYICEASNTLGQASASADFDAQ-----------------AVNVQVWP 1093
Query: 367 SLPVLEGQSLCLVCVTHSSPPARL--SWTQRGQVLSPSQPSDPGVLELPRVQVEHEGEFT 424
V EGQ + L C+ ++ PA+L +W Q GQ Q D + LP V V +
Sbjct: 1094 GATVREGQLVNLTCLVWTTHPAQLTYTWYQDGQ-----QRLDAHSIPLPNVTVRDATSYR 1148
Query: 425 CHARHPLGSQHVS--LSLSVHYSPKLLGPSCSWEAEGLHCS---CSSQASPAPSLRWWLG 479
C P + +S ++L V Y+P+ L + E+ G + C+ + P L
Sbjct: 1149 CGVGPPGRAPRLSRPITLDVLYAPRNLRLTYLLESHGGQLALVLCTVDSRPPAQLALSHA 1208
Query: 480 EELLEGNSSQDSFEV--------TPSSAGPWANSSLSLHGGLSSGLRLRCEAWNV 526
LL +++ P G ++ S+ S G ++ L LR E V
Sbjct: 1209 GRLLASSTAASVPNTLRLELRGPQPRDEGFYSCSARSPLGQANTSLELRLEGVRV 1263
Score = 68.6 bits (166), Expect = 2e-11
Identities = 64/240 (26%), Positives = 100/240 (41%), Gaps = 40/240 (16%)
Query: 211 TDLTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEPQPQGNVPYLEAQKGQ 270
T C V + R + L V YAPR+L ++ LE+ GQ
Sbjct: 1145 TSYRCGVGPPGRAPRLSRPITLDVLYAPRNLRLTY-----------------LLESHGGQ 1187
Query: 271 FLRLLCAADSQPPATLSWVLQNRVLSSSHPWG-PRPLGLELPGVKAGDSGRYTCRAENRL 329
+LC DS+PPA L+ R+L+SS P L LEL G + D G Y+C A + L
Sbjct: 1188 LALVLCTVDSRPPAQLALSHAGRLLASSTAASVPNTLRLELRGPQPRDEGFYSCSARSPL 1247
Query: 330 GSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSS-PPA 388
G +L+L + E +RV+++ V EG + + C ++ P
Sbjct: 1248 GQANTSLELRL----EGVRVILA-------------PEAAVPEGAPITVTCADPAAHAPT 1290
Query: 389 RLSWTQRGQVLSPSQPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHV-SLSLSVHYSPK 447
+W G+ L + L R H G ++C A+ G++ +L V Y+P+
Sbjct: 1291 LYTWYHNGRWLQEGPAASLSFLVATRA---HAGAYSCQAQDAQGTRSSRPAALQVLYAPQ 1347
Score = 61.2 bits (147), Expect = 3e-09
Identities = 60/200 (30%), Positives = 81/200 (40%), Gaps = 35/200 (17%)
Query: 263 YLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSS-----------SHPWGPRPLGLELP 311
+LE Q G L C+ S+P ATL +L+S S GP L LE+
Sbjct: 420 FLETQAGLVGILHCSVVSEPLATLVLSHGGHILASTSGDSDHSPRFSGTSGPNSLRLEIR 479
Query: 312 GVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVL 371
++ DSG Y C A N LG+ LD + R+++S A V+
Sbjct: 480 DLEETDSGEYKCSATNSLGNATSTLD----FHANAARLLISPA-------------AEVV 522
Query: 372 EGQSLCLVCVTHSS--PPARLSWTQRGQVLSPSQPSDPGVLELPRVQVEHEGEFTCHAR- 428
EGQ++ L C + S P AR SW G +L S L LP G + C AR
Sbjct: 523 EGQAVTLSCRSGLSPTPDARFSWYLNGALLHEGPGSS---LLLPAASSTDAGSYHCRARD 579
Query: 429 -HPLGSQHVSLSLSVHYSPK 447
H L+V Y P+
Sbjct: 580 GHSASGPSSPAVLTVLYPPR 599
Score = 57.4 bits (137), Expect = 4e-08
Identities = 96/366 (26%), Positives = 131/366 (35%), Gaps = 75/366 (20%)
Query: 146 PDVYIPETLEPGQPVTVICVFNWAFEECPPPSFSWTGAALSSQGTKPTTSHFSVLSFTPR 205
P+ +PE G P+TV C A P ++W Q P S LSF
Sbjct: 1267 PEAAVPE----GAPITVTCADPAAHA---PTLYTWYHNGRWLQ-EGPAAS----LSFLVA 1314
Query: 206 PQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEPQPQGNVPYLE 265
+ H +C +G + R L+V YAP+D V+S RD
Sbjct: 1315 TRAHAGAYSCQAQ-DAQGTRSSRPAALQVLYAPQDAVLSSFRD----------------- 1356
Query: 266 AQKGQFLRLLCAADSQPPATLSWVLQNRVLSSS-----------HPWGPR-PLGLELPGV 313
++ + C DS+PPA L+ +VL++S H R L L++ V
Sbjct: 1357 SRARSMAVIQCTVDSEPPAELALSHDGKVLATSSGVHSLASGTGHVQVARNALRLQVQDV 1416
Query: 314 KAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEG 373
AGD Y C A+N LGS L V E RV+ L V EG
Sbjct: 1417 PAGDD-TYVCTAQNLLGSISTIGRLQV----EGARVVAE-------------PGLDVPEG 1458
Query: 374 QSLCLVCVTHSSP----PARLSWTQRGQVLSPSQPSDPGVLELPRVQVEHEGEFTCHARH 429
+L L C P + +W + L + R Q G + C A
Sbjct: 1459 AALNLSCRLLGGPGPVGNSTFAWFWNDRRLHAEPVPTLAFTHVARAQA---GMYHCLAEL 1515
Query: 430 PLG-SQHVSLSLSVHYSPKLLGPSCSWEAEG-----LHCSCSSQASPAPSLRWWLGEELL 483
P G + + L V Y PK E EG L C S+ P SL LG L+
Sbjct: 1516 PTGAAASAPVMLRVLYPPKTPTMMVFVEPEGGLRGILDCRVDSE--PLASLTLHLGSRLV 1573
Query: 484 EGNSSQ 489
+ Q
Sbjct: 1574 ASSQPQ 1579
Score = 53.9 bits (128), Expect = 5e-07
Identities = 117/474 (24%), Positives = 162/474 (34%), Gaps = 78/474 (16%)
Query: 91 QLTGDPAKGNCSLVIRDAQMQDESQYFFRVERGSYVRYNFMNDGFFLKVTALTQKPDVYI 150
+ +G + L IRD + D +Y + ++ F L P +
Sbjct: 464 RFSGTSGPNSLRLEIRDLEETDSGEYKCSATNSLGNATSTLD--FHANAARLLISPAAEV 521
Query: 151 PETLEPGQPVTVICVFNWAFEECPPPSFSW--TGAALSSQGTKPTTSHFSVLSFTPRPQD 208
E GQ VT+ C P FSW GA L H S P
Sbjct: 522 VE----GQAVTLSC--RSGLSPTPDARFSWYLNGALL----------HEGPGSSLLLPAA 565
Query: 209 HNTDLTCHVDFSRKGVSAQ---RTVRLRVAYAPRDLVISISRDNTPALEPQPQGNVPYLE 265
+TD + +R G SA L V Y PR + D A
Sbjct: 566 SSTDAGSYHCRARDGHSASGPSSPAVLTVLYPPRQPTFTTRLDLDAA------------G 613
Query: 266 AQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWG------------------PRPLG 307
A G+ LLC DS PPA L + ++RV+++S P G P L
Sbjct: 614 AGAGRRGLLLCRVDSDPPARLQLLHKDRVVATSLPSGGGCSTCGGCSPRMKVTKAPNLLR 673
Query: 308 LELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTS 367
+E+ + G Y C A N LG+ + + Q TVL + T
Sbjct: 674 VEIHNPLLEEEGLYLCEASNALGNASTSATFNGQ--------------ATVLAIAPSHTL 719
Query: 368 LPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSDPGVLELPRVQVEHEGEFTCHA 427
E C V + PA SW + G VL P + L LP + + + C
Sbjct: 720 QEGTEANLTCNVSREAAGSPANFSWFRNG-VLWAQGPLETVTL-LPVARTD-AALYACRI 776
Query: 428 RHPLGSQ-HVSLSLSVHYSPKLLGPSCSWEAEGLHCS---CSSQASPAPSLRWWLGEELL 483
G+Q + LSV Y P S + H + C+ + P L + GE LL
Sbjct: 777 LTEAGAQLSTPVLLSVLYPPDRPKLSALLDMGQGHMALFICTVDSRPLALLALFHGEHLL 836
Query: 484 EGNSSQDSFEVTPSSAGPWANSSLSLHG---GLSSGLRLRCEAWNVHGAQSGSI 534
+ A AN SL L GL RCEA NV G+ + S+
Sbjct: 837 ATSLGPQVPSHGRFQAKAEAN-SLKLEVRELGLGDSGSYRCEATNVLGSSNTSL 889
Score = 47.8 bits (112), Expect = 4e-05
Identities = 36/121 (29%), Positives = 55/121 (45%), Gaps = 29/121 (23%)
Query: 223 GVSAQRTVRLRVAYAPRDLVISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQP 282
G +A V LRV Y P+ TP + + ++E + G L C DS+P
Sbjct: 1518 GAAASAPVMLRVLYPPK----------TPTM-------MVFVEPEGGLRGILDCRVDSEP 1560
Query: 283 PATLSWVLQNRVLSSSHPWG------------PRPLGLELPGVKAGDSGRYTCRAENRLG 330
A+L+ L +R+++SS P G P L +++ ++ D G Y C A N LG
Sbjct: 1561 LASLTLHLGSRLVASSQPQGAPAEPHIHVLASPNALRVDIEALRPSDQGEYICSASNVLG 1620
Query: 331 S 331
S
Sbjct: 1621 S 1621
Score = 37.7 bits (86), Expect = 0.036
Identities = 53/200 (26%), Positives = 77/200 (38%), Gaps = 39/200 (19%)
Query: 262 PYLEAQKGQFLRLLCAADSQPP----ATLSWVLQNRVLSSSHPWGPRPLGLELPGVKAGD 317
P L+ +G L L C P +T +W +R L + P P L V
Sbjct: 1451 PGLDVPEGAALNLSCRLLGGPGPVGNSTFAWFWNDRRLHAE----PVPT-LAFTHVARAQ 1505
Query: 318 SGRYTCRAENRLGSQQRA-LDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSL 376
+G Y C AE G+ A + L V YPP+ +MV L +
Sbjct: 1506 AGMYHCLAELPTGAAASAPVMLRVLYPPKTPTMMVFVEPEGGLRGI-------------- 1551
Query: 377 CLVCVTHSSPPARLSWTQRGQVLSPSQP----SDPGVLELP-----RVQVE-----HEGE 422
L C S P A L+ ++++ SQP ++P + L RV +E +GE
Sbjct: 1552 -LDCRVDSEPLASLTLHLGSRLVASSQPQGAPAEPHIHVLASPNALRVDIEALRPSDQGE 1610
Query: 423 FTCHARHPLGSQHVSLSLSV 442
+ C A + LGS S V
Sbjct: 1611 YICSASNVLGSASTSTYFGV 1630
>gi|130980072 CD33 antigen isoform 2 precursor [Homo sapiens]
Length = 237
Score = 105 bits (261), Expect = 2e-22
Identities = 50/99 (50%), Positives = 65/99 (65%), Gaps = 2/99 (2%)
Query: 142 LTQKPDVYIPETLEPGQPVTVICVFNWAFEECPPPSFSWTGAALSSQGTKPTTSHFSVLS 201
LT +P + IP TLEPG + C +WA E+ PP FSW AA +S G P T+H SVL
Sbjct: 14 LTHRPKILIPGTLEPGHSKNLTCSVSWACEQGTPPIFSWLSAAPTSLG--PRTTHSSVLI 71
Query: 202 FTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRD 240
TPRPQDH T+LTC V F+ GV+ +RT++L V Y P++
Sbjct: 72 ITPRPQDHGTNLTCQVKFAGAGVTTERTIQLNVTYVPQN 110
Score = 56.2 bits (134), Expect = 1e-07
Identities = 45/148 (30%), Positives = 59/148 (39%), Gaps = 42/148 (28%)
Query: 550 NGAFLGIGITALLFLCLALIIMKILPKRRTQTETPRPRFSRHSTILDYINVVPTAGPLAQ 609
+GA G G+TALL LCL LI + RR T R H PT G +
Sbjct: 132 HGAIGGAGVTALLALCLCLIFFIVKTHRRKAARTAVGRNDTH----------PTTGSASP 181
Query: 610 KRNQKATPNSPRTPLPPGAPSPESKKNQKKQYQLPSFPEPKSSTQAPESQESQEELHYAT 669
K +K+ + P E S + A + E EELHYA+
Sbjct: 182 KHQKKSKLHGPT--------------------------ETSSCSGAAPTVEMDEELHYAS 215
Query: 670 LNFPGVRPRPEARMPKGTQADYAEVKFQ 697
LNF G+ P K T +Y+EV+ Q
Sbjct: 216 LNFHGMNP------SKDTSTEYSEVRTQ 237
>gi|27735027 hypothetical protein LOC284369 [Homo sapiens]
Length = 197
Score = 95.1 bits (235), Expect = 2e-19
Identities = 57/138 (41%), Positives = 78/138 (56%), Gaps = 5/138 (3%)
Query: 447 KLLGPSCSWEAEGLHCSCSSQASPAPSLRWWLGEELLEGNSSQDSFEVTPSSAGPWANSS 506
KLL SCS E + L CSCS P PS++WW+G + + S +VT + GPWANS+
Sbjct: 11 KLLNSSCSLE-KTLQCSCSFHGIPTPSVQWWMGGVPVGVDGMDGSLQVTSTMLGPWANST 69
Query: 507 LSLHGGLSSGLRLRCEAWNVHGAQSGSILQLPDKKGLISTAFSNGAFLG---IGIT-ALL 562
+SL G+RL CE N +G + SIL + K L + AF G G GI ALL
Sbjct: 70 ISLTEEPEMGMRLLCEGKNQNGTHALSILLMSRKSSLAAQAFVKGLIQGAIYAGIVIALL 129
Query: 563 FLCLALIIMKILPKRRTQ 580
FLCL +I+K + K++ +
Sbjct: 130 FLCLLPLIVKHIRKKQAK 147
>gi|157168355 CD22 molecule [Homo sapiens]
Length = 847
Score = 94.7 bits (234), Expect = 3e-19
Identities = 110/492 (22%), Positives = 191/492 (38%), Gaps = 70/492 (14%)
Query: 1 MLLPLLLSSLLGGSQAMDGRFWI-RVQESVMVPEGLCISVPCSFSYPRQDWTGSTPAYGY 59
+L P LL +L D W+ E++ EG C+ +PC++ D +
Sbjct: 3 LLGPWLLLLVLEYLAFSDSSKWVFEHPETLYAWEGACVWIPCTYRALDGDLESFILFHNP 62
Query: 60 WFKAVTETTKGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFR 119
+ T G + + + +V S + R Q GD K NC+L I + D Q R
Sbjct: 63 EYNKNTSKFDGTRLYESTKDGKVP-SEQKRVQFLGDKNK-NCTLSIHPVHLNDSGQLGLR 120
Query: 120 VERGSYVRYNFMNDGFFLKVTALTQKPDVYIPETLEPGQPVTVICVFN-----------W 168
+E + + L V+ P + +P ++ Q VT+ C+ N W
Sbjct: 121 MES----KTEKWMERIHLNVSERPFPPHIQLPPEIQESQEVTLTCLLNFSCYGYPIQLQW 176
Query: 169 AFEECPPPSFSWTGAALSSQGTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQR 228
E P + T +L+ + S L F+P+ H +TC + + +
Sbjct: 177 LLEGVPMRQAAVTSTSLTIKSVFTR----SELKFSPQWSHHGKIVTCQLQDADGKFLSND 232
Query: 229 TVRLRVAYAPRDLVISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPP--ATL 286
TV+L V + P+ L I ++ + E G + + C S P T+
Sbjct: 233 TVQLNVKHTPK-LEIKVTPSDAIVRE--------------GDSVTMTCEVSSSNPEYTTV 277
Query: 287 SWVLQNRVLSSSHPWGPRPLGLELPGVKAGDSGRYTCRAENRLG-SQQRALDLSVQYPPE 345
SW+ L + + L L V SG+Y C+ N +G + + L VQY PE
Sbjct: 278 SWLKDGTSLKKQNTF-----TLNLREVTKDQSGKYCCQVSNDVGPGRSEEVFLQVQYAPE 332
Query: 346 NLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSP-PARLSWTQRGQVLSPSQP 404
V + + P +EG + +C++ ++P P +W G+ + Q
Sbjct: 333 PSTVQILHS--------------PAVEGSQVEFLCMSLANPLPTNYTWYHNGKEM---QG 375
Query: 405 SDPGVLELPRVQVEHEGEFTCHARHPLGS--QHVSLSLSVHYSPK-----LLGPSCSWEA 457
+ +P++ H G ++C A + LG+ + L V Y PK + P E
Sbjct: 376 RTEEKVHIPKILPWHAGTYSCVAENILGTGQRGPGAELDVQYPPKKVTTVIQNPMPIREG 435
Query: 458 EGLHCSCSSQAS 469
+ + SC+ +S
Sbjct: 436 DTVTLSCNYNSS 447
Score = 77.4 bits (189), Expect = 4e-14
Identities = 96/368 (26%), Positives = 151/368 (41%), Gaps = 65/368 (17%)
Query: 157 GQPVTVICVFNWAFEECPPPSFSWTGAALSSQGTKPTTSHFSVLSFTPRPQDHNTDLTCH 216
G VT+ C + + E S+ G +L Q T L+ +D + C
Sbjct: 258 GDSVTMTCEVSSSNPEYTTVSWLKDGTSLKKQNT-------FTLNLREVTKDQSGKYCCQ 310
Query: 217 VDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLC 276
V + G V L+V YAP + I ++PA+E G + LC
Sbjct: 311 VS-NDVGPGRSEEVFLQVQYAPEPSTVQIL--HSPAVE--------------GSQVEFLC 353
Query: 277 AADSQP-PATLSWVLQNRVLSSSHPWGPRPLGLELPGVKAGDSGRYTCRAENRLGSQQR- 334
+ + P P +W + + G + +P + +G Y+C AEN LG+ QR
Sbjct: 354 MSLANPLPTNYTWYHNGKEMQ-----GRTEEKVHIPKILPWHAGTYSCVAENILGTGQRG 408
Query: 335 -ALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPA--RLS 391
+L VQYPP+ + TV++N +P+ EG ++ L C +SS P+ R
Sbjct: 409 PGAELDVQYPPKKV--------TTVIQN-----PMPIREGDTVTLSCNYNSSNPSVTRYE 455
Query: 392 WTQRGQVLSPSQPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHYSP----- 446
W G PS GVL++ V ++ C A + S ++L+V Y+P
Sbjct: 456 WKPHGAWEEPSL----GVLKIQNVGWDNT-TIACAACNSWCSWASPVALNVQYAPRDVRV 510
Query: 447 ---KLLGPSCSWEAEGLHCSCSSQASPAPSLRWWLGEELLEGNSSQDSFE-VTPSSAGP- 501
K L S + L C SS + P +W L G SQ +F+ ++P AG
Sbjct: 511 RKIKPLSEIHSGNSVSLQCDFSS-SHPKEVQFFWEKNGRLLGKESQLNFDSISPEDAGSY 569
Query: 502 --WANSSL 507
W N+S+
Sbjct: 570 SCWVNNSI 577
Score = 70.1 bits (170), Expect = 7e-12
Identities = 61/226 (26%), Positives = 93/226 (41%), Gaps = 42/226 (18%)
Query: 230 VRLRVAYAPRDLVISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLS-- 287
V L V YAPRD+ + + P E G + L C S P +
Sbjct: 497 VALNVQYAPRDVRVRKIK--------------PLSEIHSGNSVSLQCDFSSSHPKEVQFF 542
Query: 288 WVLQNRVLSSSHPWGPRPLGLELPGVKAGDSGRYTCRAENRLG-SQQRALDLSVQYPPEN 346
W R+L L + D+G Y+C N +G + +A L V Y P
Sbjct: 543 WEKNGRLLGKESQ-------LNFDSISPEDAGSYSCWVNNSIGQTASKAWTLEVLYAPRR 595
Query: 347 LRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPP-ARLSWTQRGQVLSPSQPS 405
LRV +S ++ V+EG+S L C + ++PP + +W + S P
Sbjct: 596 LRVSMSPGDQ-------------VMEGKSATLTCESDANPPVSHYTWFDWN---NQSLPY 639
Query: 406 DPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLS-LSVHYSPKLLG 450
L L V+V+H G + C + +G LS L+V+YSP+ +G
Sbjct: 640 HSQKLRLEPVKVQHSGAYWCQGTNSVGKGRSPLSTLTVYYSPETIG 685
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 90.5 bits (223), Expect = 5e-18
Identities = 66/231 (28%), Positives = 103/231 (44%), Gaps = 29/231 (12%)
Query: 272 LRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG--LELPGVKAGDSGRYTCRAENRL 329
+ L C ++ PP TL+W L+SS P G L++P K D+GRYTC A N
Sbjct: 2795 ISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEA 2854
Query: 330 GSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPAR 389
G D+ V PP ++ AN + E + VL +S + C++ SP R
Sbjct: 2855 GEDSLQYDVRVLVPP-----IIKGANSDLPE------EVTVLVNKSALIECLSSGSPAPR 2903
Query: 390 LSWTQRGQVLSPSQP----SDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHYS 445
SW + GQ L S+ +L++ Q+ G + C A + GS +L+VH
Sbjct: 2904 NSWQKDGQPLLEDDHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHVP 2963
Query: 446 PKLLGPSCSWEAEGL--------HCSCSSQASPAPSLRWWLGEELLEGNSS 488
P ++GP ++E L +C P P L W E+ ++ N++
Sbjct: 2964 PSVIGP----KSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTN 3010
Score = 87.4 bits (215), Expect = 4e-17
Identities = 68/227 (29%), Positives = 102/227 (44%), Gaps = 17/227 (7%)
Query: 272 LRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG--LELPGVKAGDSGRYTCRAENRL 329
L L C A + P A+LSW + L S G L++ + D+GRYTC A N
Sbjct: 2692 LTLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIA 2751
Query: 330 GSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPAR 389
G + D+++Q PP ++ +L+ NG + V+ + L C T+++PP
Sbjct: 2752 GEDELDFDVNIQVPPSFQKLW---EIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPT 2808
Query: 390 LSWTQRGQVLSPSQP--SDPG--VLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHYS 445
L+W + G L+ S PG VL++PR +VE G +TC A + G + + V
Sbjct: 2809 LTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVP 2868
Query: 446 PKLLGPSCSWEAE-------GLHCSCSSQASPAPSLRWWL-GEELLE 484
P + G + E C S SPAP W G+ LLE
Sbjct: 2869 PIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLE 2915
Score = 85.1 bits (209), Expect = 2e-16
Identities = 68/268 (25%), Positives = 118/268 (44%), Gaps = 27/268 (10%)
Query: 271 FLRLLCAADSQPPATLSWVLQNRV--LSSSHPWGPRPLGLELPGVKAGDSGRYTCRAENR 328
F+ L C PP LSW+ + L+++ P L++ K D G YTC A N+
Sbjct: 2981 FISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQ 3040
Query: 329 LGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPA 388
G ++ L+V PP +++ S++ V V EG S+ L C +++ PP
Sbjct: 3041 AGESKKKFSLTVYVPP-SIKDHDSESLSVV----------NVREGTSVSLECESNAVPPP 3089
Query: 389 RLSWTQRGQVLSPSQP----SDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHY 444
++W + G++++ S +D +L + + +V G++ C A + G + L+V+
Sbjct: 3090 VITWYKNGRMITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYV 3149
Query: 445 SPKLLGPSCSWEAEGLH----CSCSSQASPAPSLRWWLGEELLEGNSSQDSFEVTPSSAG 500
P + GP E + +C + P P++ W + +E + DS EV S G
Sbjct: 3150 PPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIE---NSDSLEVRILSGG 3206
Query: 501 PWANSSLSLHGGLSSGLRLRCEAWNVHG 528
+ S H S C A N+ G
Sbjct: 3207 SKLQIARSQH---SDSGNYTCIASNMEG 3231
Score = 82.0 bits (201), Expect = 2e-15
Identities = 65/228 (28%), Positives = 98/228 (42%), Gaps = 39/228 (17%)
Query: 272 LRLLCAADSQPPATLSW---------VLQNRVLSSSHPWGPRPLGLELPGVKAGDSGRYT 322
+ L C AD PP ++W ++ RVLSS L++ V+ GD+G YT
Sbjct: 4096 ITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSG--------SLQIAFVQPGDAGHYT 4147
Query: 323 CRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVT 382
C A N GS + L+V PP R+ ++ + TV EN L CV
Sbjct: 4148 CMAANVAGSSSTSTKLTVHVPP---RIRSTEGHYTVNEN------------SQAILPCVA 4192
Query: 383 HSSPPARLSWTQRGQVLS---PSQPSDP-GVLELPRVQVEHEGEFTCHARHPLGSQHVSL 438
P ++W + +L+ ++P G L L V +E G +TC A + G ++
Sbjct: 4193 DGIPTPAINWKKDNVLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTV 4252
Query: 439 SLSVHYSP---KLLGPSCSWEAEGLHCSCSSQASPAPSLRWWLGEELL 483
SL+VH P +L G + E L SC + P P L W ++
Sbjct: 4253 SLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTWTFNNNII 4300
Score = 78.6 bits (192), Expect = 2e-14
Identities = 59/235 (25%), Positives = 98/235 (41%), Gaps = 24/235 (10%)
Query: 274 LLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG--LELPGVKAGDSGRYTCRAENRLGS 331
L C +D+ PP ++W+ L ++ G L++ GD+ YTC A N G
Sbjct: 3641 LECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGK 3700
Query: 332 QQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPARLS 391
R L+V PP N++ G SL +L +S L C+ P R++
Sbjct: 3701 TTREFILTVNVPP-NIK--------------GGPQSLVILLNKSTVLECIAEGVPTPRIT 3745
Query: 392 WTQRGQVLSPSQPS----DPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHYSPK 447
W + G VL+ + + G L + V G + C A + G+ + L VH P
Sbjct: 3746 WRKDGAVLAGNHARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPS 3805
Query: 448 LL-GPSCSWEAEGLH--CSCSSQASPAPSLRWWLGEELLEGNSSQDSFEVTPSSA 499
+ GP+ + +C + P PS+ W LL + +Q+S+ + S +
Sbjct: 3806 IAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGS 3860
Score = 76.3 bits (186), Expect = 9e-14
Identities = 60/218 (27%), Positives = 94/218 (43%), Gaps = 29/218 (13%)
Query: 272 LRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG----LELPGVKAGDSGRYTCRAEN 327
+RL C A P +L+W+ +SS G + L L L + D+GRYTC A N
Sbjct: 2029 VRLECEARGIPAPSLTWLKDGSPVSSFSN-GLQVLSGGRILALTSAQISDTGRYTCVAVN 2087
Query: 328 RLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPP 387
G +QR +DL V PP +G ++ VL Q++ L+C + + PP
Sbjct: 2088 AAGEKQRDIDLRVYVPP---------------NIMGEEQNVSVLISQAVELLCQSDAIPP 2132
Query: 388 ARLSWTQRGQVL----SPSQPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVH 443
L+W + G L S + VL++ QV+ G +TC A + G + ++++
Sbjct: 2133 PTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIW 2192
Query: 444 YSPKLLGPS-----CSWEAEGLHCSCSSQASPAPSLRW 476
P + G E + C S P P+L W
Sbjct: 2193 VPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIW 2230
Score = 76.3 bits (186), Expect = 9e-14
Identities = 55/220 (25%), Positives = 93/220 (42%), Gaps = 23/220 (10%)
Query: 268 KGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG--LELPGVKAGDSGRYTCRA 325
+G+ + L C PP T++W+ L + G L+L + D+GRY C A
Sbjct: 2306 RGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVA 2365
Query: 326 ENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSS 385
N G + DLSV PP +++ N + ++ V+E S+ L C
Sbjct: 2366 VNVAGMTDKKYDLSVHAPP------------SIIGNHRSPENISVVEKNSVSLTCEASGI 2413
Query: 386 PPARLSWTQRGQVLSPSQP----SDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLS 441
P ++W + G +S S S +L L + +E G++TC R+ G + LS
Sbjct: 2414 PLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLS 2473
Query: 442 VHYSPKLLGPSC-----SWEAEGLHCSCSSQASPAPSLRW 476
V P ++G + E + + +C +P P + W
Sbjct: 2474 VLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITW 2513
Score = 75.1 bits (183), Expect = 2e-13
Identities = 86/368 (23%), Positives = 137/368 (37%), Gaps = 72/368 (19%)
Query: 140 TALTQKPDVYIPETLEPGQPVTVICVFNWAFEEC-----PPPSFSWT--GAALSS-QGTK 191
T L V++ ++ + + V N EC P PS +W G+ +SS
Sbjct: 2000 TELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGL 2059
Query: 192 PTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTP 251
S +L+ T TC V + G QR + LRV Y P
Sbjct: 2060 QVLSGGRILALTSAQISDTGRYTC-VAVNAAG-EKQRDIDLRV-YVP------------- 2103
Query: 252 ALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRP------ 305
P G + Q + LLC +D+ PP TL+W L HP +P
Sbjct: 2104 ---PNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTW------LKDGHPLLKKPGLSISE 2154
Query: 306 --LGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLG 363
L++ + D+GRYTC A N G ++ ++++ PP N+G
Sbjct: 2155 NRSVLKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPP----------------NIG 2198
Query: 364 NG---TSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQ-VLSPSQP-----SDPGVLELPR 414
T L V+EG + L+C + PP L W ++G VL+ S S L++
Sbjct: 2199 GSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISI 2258
Query: 415 VQVEHEGEFTCHARHPLGSQHVSLSLSVHYSPKLLGPSCS------WEAEGLHCSCSSQA 468
+ ++C A + G+ +L V+ P + + + C Q
Sbjct: 2259 AEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECEVQG 2318
Query: 469 SPAPSLRW 476
P P++ W
Sbjct: 2319 IPPPTVTW 2326
Score = 73.9 bits (180), Expect = 5e-13
Identities = 61/227 (26%), Positives = 92/227 (40%), Gaps = 27/227 (11%)
Query: 274 LLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG--LELPGVKAGDSGRYTCRAENRLGS 331
L C A P +++W +S S+ G L L D+G+YTC N G
Sbjct: 2406 LTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGE 2465
Query: 332 QQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPARLS 391
+++ LSV PP + LE++ V E QS+ L C +P ++
Sbjct: 2466 ERKIFGLSVLVPPHIV-------GENTLEDV------KVKEKQSVTLTCEVTGNPVPEIT 2512
Query: 392 WTQRGQVLSPSQP----SDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHYSPK 447
W + GQ L + S L++ VQV H G +TC A P G + S SL+V SP
Sbjct: 2513 WHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPT 2572
Query: 448 LLGPSCSWEAEGL--------HCSCSSQASPAPSLRWWLGEELLEGN 486
+ G E + C + + P ++ W+ LE N
Sbjct: 2573 IAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESN 2619
Score = 73.6 bits (179), Expect = 6e-13
Identities = 77/327 (23%), Positives = 118/327 (36%), Gaps = 49/327 (14%)
Query: 174 PPPSFSWTGAALSSQGTKPTTSHFSVLSFTP-----RPQDHNTDLTCHVDFSRKGVSAQR 228
PPP +W L P +SH +L+ R Q + + V +R GV +
Sbjct: 3370 PPPQINWLKNGLPL----PLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVD-NK 3424
Query: 229 TVRLRVAYAPRDLVISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSW 288
L+V +AP ++ S+ + L KG + C D P +++W
Sbjct: 3425 HYNLQV-FAPPNMDNSMGTEEITVL--------------KGSSTSMACITDGTPAPSMAW 3469
Query: 289 VLQNRVLSSSHPWGPRPLGLELPGVKAG--DSGRYTCRAENRLGSQQRALDLSVQYPPEN 346
+ + L G+ L +KA DSG+YTC A N G + L V PP
Sbjct: 3470 LRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPH- 3528
Query: 347 LRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSD 406
+ + V+ L L C+ P +++W + G+ L +
Sbjct: 3529 ------------INGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQ 3576
Query: 407 P----GVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHYSPKLLGPSCSWEAEGLH- 461
VL + QVE G +TC A P G + VH P + G + L
Sbjct: 3577 TLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRN 3636
Query: 462 ----CSCSSQASPAPSLRWWLGEELLE 484
C S A P P + W E L+
Sbjct: 3637 RQVTLECKSDAVPPPVITWLRNGERLQ 3663
Score = 73.2 bits (178), Expect = 8e-13
Identities = 69/277 (24%), Positives = 113/277 (40%), Gaps = 29/277 (10%)
Query: 255 PQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLGLELPGVK 314
P Q L +G + L C A P ++ W + ++S+S L V
Sbjct: 981 PTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVS 1040
Query: 315 AG--DSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLE 372
G +SG Y C A N G +R + L+V P RV Q + + VL
Sbjct: 1041 PGGEESGEYVCTATNTAGYAKRKVQLTVYVRP---RVFGDQRGLSQ----DKPVEISVLA 1093
Query: 373 GQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPS----DPGVLELPRVQVEHEGEFTCHAR 428
G+ + L C S PP ++W + Q++SP P G +++ + G + C A
Sbjct: 1094 GEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVAT 1153
Query: 429 HPLGSQHVSLSLSVHYSPKL-LGPSCSWEAEG--LHCSCSSQASPAPSLRWWLGEELL-- 483
+ G+ ++ L+VH PK+ GP G + C++Q +P P + W G +
Sbjct: 1154 NIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLV 1213
Query: 484 ---------EGNSSQDSFEVTPSSAGPWANSSLSLHG 511
+G S D + TPS AG + + ++ G
Sbjct: 1214 DGEHHVSNPDGTLSID--QATPSDAGIYTCVATNIAG 1248
Score = 72.8 bits (177), Expect = 1e-12
Identities = 53/219 (24%), Positives = 95/219 (43%), Gaps = 29/219 (13%)
Query: 274 LLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG----LELPGVKAGDSGRYTCRAENRL 329
L C A PP T++W+ ++ + +S R L L++ + DSG YTC A N
Sbjct: 3171 LTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNME 3230
Query: 330 GSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPAR 389
G Q+ LS+Q PP S A + + + VL G+++ LVC + P
Sbjct: 3231 GKAQKYYFLSIQVPP-------SVAGAEI------PSDVSVLLGENVELVCNANGIPTPL 3277
Query: 390 LSWTQRGQVLSPSQ------PSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVH 443
+ W + G+ ++ + ++ L + G++TC A +P G + +L+V+
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVY 3337
Query: 444 YSPKLLGPSCSWEA------EGLHCSCSSQASPAPSLRW 476
+P + G E ++ C + +P P + W
Sbjct: 3338 VTPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQINW 3376
Score = 71.2 bits (173), Expect = 3e-12
Identities = 52/224 (23%), Positives = 91/224 (40%), Gaps = 26/224 (11%)
Query: 268 KGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG----LELPGVKAGDSGRYTC 323
+G + LLC + PP L W + + + R L L++ + D+ Y+C
Sbjct: 2210 EGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSC 2269
Query: 324 RAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTH 383
A N G+ ++ +L V P T+ + + T + V G+S+ L C
Sbjct: 2270 VASNVAGTAKKEYNLQVYIRP------------TITNSGSHPTEIIVTRGKSISLECEVQ 2317
Query: 384 SSPPARLSWTQRGQVLSPSQP----SDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLS 439
PP ++W + G L ++ + +L+L + V G + C A + G
Sbjct: 2318 GIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKYD 2377
Query: 440 LSVHYSPKLLGPSCS------WEAEGLHCSCSSQASPAPSLRWW 477
LSVH P ++G S E + +C + P PS+ W+
Sbjct: 2378 LSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWF 2421
Score = 71.2 bits (173), Expect = 3e-12
Identities = 89/375 (23%), Positives = 141/375 (37%), Gaps = 68/375 (18%)
Query: 148 VYIPETLEPGQPVTVICVFNWAFEEC-----PPPSFSWT--GAALSSQGTKPTTSHFSVL 200
V +P ++ G VI + EC P P +W GA L+ + +S+L
Sbjct: 3709 VNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHAR-----YSIL 3763
Query: 201 S--FTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEPQPQ 258
F H TD ++ + +A T R R+ DL + + P++ P P
Sbjct: 3764 ENGFLHIQSAHVTDTGRYLCMA---TNAAGTDRRRI-----DLQVHVP----PSIAPGPT 3811
Query: 259 GNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPL----GLELPGVK 314
+ Q L C A P +++W +L+ L L +
Sbjct: 3812 NMTVIVNVQT----TLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPS 3867
Query: 315 AGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQ 374
D+ Y C N G +R +DL+VQ PP S A+ T V +
Sbjct: 3868 VDDTATYECTVTNGAGDDKRTVDLTVQVPP-------SIADEP--------TDFLVTKHA 3912
Query: 375 SLCLVCVTHSSPPARLSWTQRGQVLSPSQPS----DPGVLELPRVQVEHEGEFTCHARHP 430
+ C P + WT+ G L P G +E+ Q+ H G +TC AR+
Sbjct: 3913 PAVITCTASGVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNA 3972
Query: 431 LGSQHVSLSLSVHYSPKLLGPSCSWEAEGLH--------CSCSSQASPAPSLRWWLGEEL 482
GS H ++L VH P ++ P + LH C + +P+P + W +E
Sbjct: 3973 AGSAHRHVTLHVH-EPPVIQP----QPSELHVILNNPILLPCEATGTPSPFITW--QKEG 4025
Query: 483 LEGNSSQDSFEVTPS 497
+ N+S + V PS
Sbjct: 4026 INVNTSGRNHAVLPS 4040
Score = 70.1 bits (170), Expect = 7e-12
Identities = 63/296 (21%), Positives = 121/296 (40%), Gaps = 39/296 (13%)
Query: 251 PALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG--L 308
P+++ ++ + ++G + L C +++ PP ++W R+++ S G L
Sbjct: 3056 PSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQML 3115
Query: 309 ELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSL 368
+ + D+G+Y CRA N G + L+V PP + ++E + N
Sbjct: 3116 HIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPS----IEGPEREVIVETISN---- 3167
Query: 369 PVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQP------SDPGVLELPRVQVEHEGE 422
+ L C PP ++W + + + S S L++ R Q G
Sbjct: 3168 ------PVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGN 3221
Query: 423 FTCHARHPLGSQHVSLSLSVHYSPKLLGPSCSWE-----AEGLHCSCSSQASPAPSLRWW 477
+TC A + G LS+ P + G + E + C++ P P ++W
Sbjct: 3222 YTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQW- 3280
Query: 478 LGEELLEGN--SSQDSFEVTPSSAGPWANSSLSLHGGLSSGL-RLRCEAWNVHGAQ 530
L +G +S ++ + S+ G S+L+++G L+S + C A N G +
Sbjct: 3281 ----LKDGKPIASGETERIRVSANG----STLNIYGALTSDTGKYTCVATNPAGEE 3328
Score = 69.3 bits (168), Expect = 1e-11
Identities = 55/226 (24%), Positives = 95/226 (42%), Gaps = 30/226 (13%)
Query: 274 LLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG--LELPGVKAGDSGRYTCRAENRLGS 331
L+C A S PPAT++W L S+ P G L++ + ++GRY+C A N G
Sbjct: 2595 LVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGE 2654
Query: 332 QQRALDLSVQYPPENLRVMVSQANRTVLENLG-NGTSLPVLEGQSLCLVCVTHSSPPARL 390
+ ++ V PP N+ L G + + + +L L C ++ P A L
Sbjct: 2655 MIKHYEVKVYIPPI--------INKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASL 2706
Query: 391 SWTQRGQVLSPSQ----PSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHYSP 446
SW + GQ L ++ L++ Q+ G +TC A + G + +++ P
Sbjct: 2707 SWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPP 2766
Query: 447 ---------KLLGPSCSWEAEG------LHCSCSSQASPAPSLRWW 477
+L + EA+ + C + A+P P+L W+
Sbjct: 2767 SFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWY 2812
Score = 68.6 bits (166), Expect = 2e-11
Identities = 50/179 (27%), Positives = 74/179 (41%), Gaps = 23/179 (12%)
Query: 308 LELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTS 367
L L + D GRY C N G Q + + L++ PP + N T T
Sbjct: 1510 LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYIPPS-----IKGGNVT--------TD 1556
Query: 368 LPVLEGQSLCLVCVTHSSPPARLSWTQRGQ-VLSPSQP--SDPG-VLELPRVQVEHEGEF 423
+ VL + L C T P ++W + GQ ++S SQ D G L +PR QV +
Sbjct: 1557 ISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATY 1616
Query: 424 TCHARHPLGSQHVSLSLSVHYSPKLLGPSCS------WEAEGLHCSCSSQASPAPSLRW 476
TCH + G+ S + V+ P + G + A L C + +P+P L W
Sbjct: 1617 TCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTW 1675
Score = 68.2 bits (165), Expect = 3e-11
Identities = 80/353 (22%), Positives = 130/353 (36%), Gaps = 52/353 (14%)
Query: 147 DVYIPETLE-PGQPVTVICVFNWAFEEC-----PPPSFSWTGAALSSQGTKPTT----SH 196
+VY+P ++E P + V V + N C PPP+ +W + + S
Sbjct: 3146 NVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSG 3205
Query: 197 FSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEPQ 256
S L + + TC S AQ+ L + P I D + L
Sbjct: 3206 GSKLQIARSQHSDSGNYTCIA--SNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLL--- 3260
Query: 257 PQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG----LELPG 312
G+ + L+C A+ P + W+ + ++S R L + G
Sbjct: 3261 ------------GENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYG 3308
Query: 313 VKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLE 372
D+G+YTC A N G + R +L+V P T+ N L L
Sbjct: 3309 ALTSDTGKYTCVATNPAGEEDRIFNLNVYVTP------------TIRGNKDEAEKLMTLV 3356
Query: 373 GQSLCLVCVTHSSPPARLSWTQRGQVLSPSQP----SDPGVLELPRVQVEHEGEFTCHAR 428
S+ + C +PP +++W + G L S + V+ + R QV +TC A
Sbjct: 3357 DTSINIECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVAS 3416
Query: 429 HPLGSQHVSLSLSVHYSPKLLGPSCSWEAEGLHCS-----CSSQASPAPSLRW 476
+ G + +L V P + + E L S C + +PAPS+ W
Sbjct: 3417 NRAGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAW 3469
Score = 67.0 bits (162), Expect = 6e-11
Identities = 54/250 (21%), Positives = 102/250 (40%), Gaps = 28/250 (11%)
Query: 251 PALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLGLEL 310
PA+E + + Y L L C PP T+ W+ +++ + G +L
Sbjct: 1733 PAIEGGDETS--YFIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKL 1790
Query: 311 PGVKA--GDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSL 368
+A ++G Y C A N G ++ +++V PP + S + V
Sbjct: 1791 VIAQAQVSNTGLYRCMAANTAGDHKKEFEVTVHVPP---TIKSSGLSERV---------- 1837
Query: 369 PVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQ-----PSDPGVLELPRVQVEHEGEF 423
V++ + + L C+ + P ++W + Q ++ +Q S VL++ + +E G +
Sbjct: 1838 -VVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRY 1896
Query: 424 TCHARHPLGSQHVSLSLSVHYSPKL-----LGPSCSWEAEGLHCSCSSQASPAPSLRWWL 478
TC A + G + L VH P L + + + C + +P P + W+
Sbjct: 1897 TCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAAGNPVPVITWYK 1956
Query: 479 GEELLEGNSS 488
LL G++S
Sbjct: 1957 DNRLLSGSTS 1966
Score = 66.2 bits (160), Expect = 1e-10
Identities = 61/278 (21%), Positives = 107/278 (38%), Gaps = 31/278 (11%)
Query: 255 PQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVL--QNRVLSSSHPWGPRPLGLELPG 312
P+ Q +L+ Q GQ + + C A P ++W ++ H L +
Sbjct: 1171 PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQ 1230
Query: 313 VKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLE 372
D+G YTC A N G+ + + L VQ PP + + N T E + N
Sbjct: 1231 ATPSDAGIYTCVATNIAGTDETEITLHVQEPP-TVEDLEPPYNTTFQERVAN-------- 1281
Query: 373 GQSLCLVCVTHSSPPARLSWTQRGQVLSPSQP-----SDPGVLELPRVQVEHEGEFTCHA 427
Q + C +P + W G+ L+ +P D +L + V GE+ C A
Sbjct: 1282 -QRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVA 1340
Query: 428 RHPLGSQHVSLSLSVHYSPKLLGPSCSWEAEGL-----HCSCSSQASPAPSLRWWLGE-E 481
+ G+ +L VH P + L + C + +P+P + W+ +
Sbjct: 1341 VNEAGTTERKYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQ 1400
Query: 482 LLEGNSSQ--------DSFEVTPSSAGPWANSSLSLHG 511
+ E ++ Q F TP AG ++ ++++ G
Sbjct: 1401 VTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAG 1438
Score = 65.5 bits (158), Expect = 2e-10
Identities = 51/215 (23%), Positives = 93/215 (43%), Gaps = 27/215 (12%)
Query: 274 LLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG-----LELPGVKAGDSGRYTCRAENR 328
L C A+ P +++W+ ++ ++++ G + L++ D+GRYTC A N
Sbjct: 1846 LQCIANGIPNPSITWLKDDQPVNTAQ--GNLKIQSSGRVLQIAKTLLEDAGRYTCVATNA 1903
Query: 329 LGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPA 388
G Q+ + L V PP LE+ G + VL + L C +P
Sbjct: 1904 AGETQQHIQLHVHEPPS-------------LEDAGKMLNETVLVSNPVQLECKAAGNPVP 1950
Query: 389 RLSWTQRGQVLSPSQP----SDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHY 444
++W + ++LS S + ++++ Q+ G + C A + G+ + SL VH
Sbjct: 1951 VITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQVHV 2010
Query: 445 SPKLLGPSCSWEA---EGLHCSCSSQASPAPSLRW 476
+P + G + + C ++ PAPSL W
Sbjct: 2011 APSISGSNNMVAVVVNNPVRLECEARGIPAPSLTW 2045
Score = 65.1 bits (157), Expect = 2e-10
Identities = 57/249 (22%), Positives = 99/249 (39%), Gaps = 28/249 (11%)
Query: 243 ISISRDNTPALEP-QPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPW 301
I++ P +E +P N + E Q + C A P T+ W+ R L+ P
Sbjct: 1254 ITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGREP- 1312
Query: 302 GPRPLG----LELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRT 357
G L L + V D+G Y C A N G+ +R +L V PP
Sbjct: 1313 GISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPP------------- 1359
Query: 358 VLENLGNGTSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQP----SDPGVLELP 413
V+++ T++ VL Q L C +P + W + ++ S ++ +L+L
Sbjct: 1360 VIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLF 1419
Query: 414 RVQVEHEGEFTCHARHPLGSQHVSLSLSVHYSPKLLGPSCSWEA-----EGLHCSCSSQA 468
R E G ++C A + G+ ++ V P ++G + E + C +
Sbjct: 1420 RATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKG 1479
Query: 469 SPAPSLRWW 477
+P P + W+
Sbjct: 1480 TPFPDIHWF 1488
Score = 64.7 bits (156), Expect = 3e-10
Identities = 70/274 (25%), Positives = 110/274 (40%), Gaps = 36/274 (13%)
Query: 269 GQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG------LELPGVKAGDSGRYT 322
G + L C P T+ W + + S P+ + L + + A D G Y
Sbjct: 807 GSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYI 866
Query: 323 CRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLP-VLEGQSLCLVC- 380
C AEN+ G Q ++V V +G S+ V+EGQ L L C
Sbjct: 867 CEAENQFGKIQSETTVTV--------------TGLVAPLIGISPSVANVIEGQQLTLPCT 912
Query: 381 VTHSSPPARLSWTQRGQVLSPSQ---PSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVS 437
+ +P W + +L + G L + RVQ++ GE+TC A + G+ + +
Sbjct: 913 LLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKT 972
Query: 438 LSLSVHYSPKLL-GPSCSWEAEGLHCS--CSSQASPAPSLRWWLGEELLEGNSSQDSFEV 494
S+ VH P + G EG+ + C + +P PS+ W EL+ +S++
Sbjct: 973 TSVVVHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTSSAK----- 1027
Query: 495 TPSSAGPWANSSLSLHGGLSSGLRLRCEAWNVHG 528
SAG + + GG SG C A N G
Sbjct: 1028 --FSAGADGSLYVVSPGGEESG-EYVCTATNTAG 1058
Score = 62.8 bits (151), Expect = 1e-09
Identities = 75/314 (23%), Positives = 116/314 (36%), Gaps = 46/314 (14%)
Query: 174 PPPSFSWT--GAALSSQGTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVR 231
P PS WT G L +G + +H TC V + G SA R V
Sbjct: 3924 PFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTC-VARNAAG-SAHRHVT 3981
Query: 232 LRVAYAPRDLVISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQ 291
L V P ++PQP L + L C A P ++W +
Sbjct: 3982 LHV-------------HEPPVIQPQPSE----LHVILNNPILLPCEATGTPSPFITWQKE 4024
Query: 292 NRVLSSS---HPWGPRPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLR 348
+++S H P GL++ D+G Y C A+N G+ + L+VQ PP
Sbjct: 4025 GINVNTSGRNHAVLPSG-GLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVPP---- 4079
Query: 349 VMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPS---QPS 405
V+ V + + + L C PP ++W + G+ + S +
Sbjct: 4080 VISPHLKEYV-----------IAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVL 4128
Query: 406 DPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHYSPKLLGPSCSW---EAEGLHC 462
G L++ VQ G +TC A + GS S L+VH P++ + E
Sbjct: 4129 SSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAIL 4188
Query: 463 SCSSQASPAPSLRW 476
C + P P++ W
Sbjct: 4189 PCVADGIPTPAINW 4202
Score = 61.2 bits (147), Expect = 3e-09
Identities = 62/283 (21%), Positives = 107/283 (37%), Gaps = 47/283 (16%)
Query: 270 QFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG--LELPGVKAGDSGRYTCRAEN 327
Q L C + P + W N ++ S G L+L D+GRY+C+A N
Sbjct: 1376 QLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAIN 1435
Query: 328 RLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLP----VLEGQSLCLVCVTH 383
G+ Q+ ++ V PP T++ GT+ P V+ + + L C
Sbjct: 1436 IAGTSQKYFNIDVLVPP------------TII-----GTNFPNEVSVVLNRDVALECQVK 1478
Query: 384 SSPPARLSWTQRGQVLSPSQPS----DPG-VLELPRVQVEHEGEFTCHARHPLGSQHVSL 438
+P + W + G+ L P+ D G VL L + +G + C + G Q +
Sbjct: 1479 GTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDI 1538
Query: 439 SLSVHYSPKLLGPSCSWEAEGL-----HCSCSSQASPAPSLRWWLGEELLEGNSSQDSFE 493
L+++ P + G + + + L C ++ P P++ W+ +D
Sbjct: 1539 KLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWY-----------KDGQP 1587
Query: 494 VTPSSAGPWANSSLSLH---GGLSSGLRLRCEAWNVHGAQSGS 533
+ SS + + LH +S C NV G S
Sbjct: 1588 IMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKS 1630
Score = 60.1 bits (144), Expect = 7e-09
Identities = 55/231 (23%), Positives = 92/231 (39%), Gaps = 27/231 (11%)
Query: 264 LEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG--LELPGVKAGDSGRY 321
++ ++ Q + L C P ++W + L G L++ V+ +GRY
Sbjct: 2489 VKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTGRY 2548
Query: 322 TCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCV 381
TC A + G + R+ L+V P V GN + V+ LVC
Sbjct: 2549 TCLASSPAGHKSRSFSLNVFVSPTIAGVGSD----------GNPEDVTVILNSPTSLVCE 2598
Query: 382 THSSPPARLSWTQRGQVLSPSQPSD--PG--VLELPRVQVEHEGEFTCHARHPLGSQHVS 437
+S PPA ++W + G L ++ PG L++ Q ++ G ++C A + G
Sbjct: 2599 AYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKH 2658
Query: 438 LSLSVHYSP-----KLLGPSCSWEA------EGLHCSCSSQASPAPSLRWW 477
+ V+ P L GP S + L C + A P+ SL W+
Sbjct: 2659 YEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWY 2709
Score = 56.6 bits (135), Expect = 8e-08
Identities = 55/237 (23%), Positives = 93/237 (39%), Gaps = 25/237 (10%)
Query: 254 EPQPQGNVPY-LEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG---LE 309
EP P VP + G+ L C S L+W +R + + P R L LE
Sbjct: 518 EPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLE 577
Query: 310 LPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLP 369
L VK D+G Y C + GS ++ L+VQ PP +V V N++
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPP---KVTVMPKNQS------------ 622
Query: 370 VLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPS---QPSDPGVLELPRVQVEHEGEFTCH 426
G + ++C P +++WT + S + + G L + + G + C
Sbjct: 623 FTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCL 682
Query: 427 ARHPLGSQHVSLSLSVHYSPKLLGPSCSW---EAEGLHCSCSSQASPAPSLRWWLGE 480
A + G+ + +L +PKL+ + C + P P ++W+ G+
Sbjct: 683 ASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGD 739
Score = 56.2 bits (134), Expect = 1e-07
Identities = 53/215 (24%), Positives = 85/215 (39%), Gaps = 20/215 (9%)
Query: 268 KGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLGLELPGVKAGDSGRYTCRAEN 327
KG+ LRL C A P L+W N ++ + L + V DSG Y C AEN
Sbjct: 4273 KGEQLRLSCKATGIPLPKLTWTFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVCTAEN 4332
Query: 328 RLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPP 387
+G + + V+ PP V +E LG + L C P
Sbjct: 4333 SVGFVKAIGFVYVKEPP----VFKGDYPSNWIEPLGG----------NAILNCEVKGDPT 4378
Query: 388 ARLSWTQRG---QVLSPSQPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHY 444
+ W ++G ++ + G L + E G++TC A + G S+SL++
Sbjct: 4379 PTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQS 4438
Query: 445 SPKL-LGPSCSWEAEG--LHCSCSSQASPAPSLRW 476
P + L P + G + +C + P P++ W
Sbjct: 4439 PPIITLEPVETVINAGGKIILNCQATGEPQPTITW 4473
Score = 55.1 bits (131), Expect = 2e-07
Identities = 49/176 (27%), Positives = 73/176 (41%), Gaps = 25/176 (14%)
Query: 274 LLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG---LELPGVKAGDSGRYTCRAENRLG 330
L C P T+ W + + SH R LG L + G D+G YTC A N G
Sbjct: 4369 LNCEVKGDPTPTIQWNRKGVDIEISHRI--RQLGNGSLAIYGTVNEDAGDYTCVATNEAG 4426
Query: 331 SQQRALDLSVQYPP----ENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSP 386
+R++ L++Q PP E + +++ + +L G P +T S
Sbjct: 4427 VVERSMSLTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPT----------ITWSRQ 4476
Query: 387 PARLSWTQRGQVLSPSQPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSV 442
+SW R VLS + L + Q E EF C AR+ +GS V + + V
Sbjct: 4477 GHSISWDDRVNVLSNNS------LYIADAQKEDTSEFECVARNLMGSVLVRVPVIV 4526
Score = 53.1 bits (126), Expect = 8e-07
Identities = 50/220 (22%), Positives = 86/220 (39%), Gaps = 24/220 (10%)
Query: 276 CAADSQPPATLSWVLQNRVLS-SSHPWGPRPLGLELPGVKAGDSGRYTCRAENRLGSQQR 334
C+ DS P TLS+V L + + L++ V D G Y C A + G+ +
Sbjct: 451 CSVDSLLPFTLSFVRNGVTLGVDQYLKESASVNLDIAKVTLSDEGFYECIAVSSAGTGRA 510
Query: 335 ALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPARLSWTQ 394
V PP ++V ++ V G+ L C+ S+ L+W +
Sbjct: 511 QTFFDVSEPPPVIQV---------------PNNVTVTPGERAVLTCLIISAVDYNLTWQR 555
Query: 395 RGQVLSPSQPSDPGV-----LELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHYSPKLL 449
+ + ++P+ LEL V+ GE+ C GS S+ L+V PK+
Sbjct: 556 NDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVT 615
Query: 450 GPSCSWEAEG---LHCSCSSQASPAPSLRWWLGEELLEGN 486
+ G + CS+ P P + W + + + G+
Sbjct: 616 VMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGS 655
Score = 52.0 bits (123), Expect = 2e-06
Identities = 76/375 (20%), Positives = 135/375 (36%), Gaps = 56/375 (14%)
Query: 145 KPDVYIPETLEPGQPVTVICVF--NWAFEEC-----PPPSFSW--TGAALSSQGTKPTTS 195
K +YIP +++ G T I V + EC P P+ +W G + S
Sbjct: 1539 KLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYID 1598
Query: 196 HFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEP 255
L + TCHV + +A+++ + V Y P P
Sbjct: 1599 KGQYLHIPRAQVSDSATYTCHV--ANVAGTAEKSFHVDV-YVP----------------P 1639
Query: 256 QPQGNVPY---LEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG--LEL 310
+GN+ + L L C A P L+W+ + ++ G LE+
Sbjct: 1640 MIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEI 1699
Query: 311 PGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPV 370
+ D G+Y C A + G ++ ++ V PP +E + V
Sbjct: 1700 MSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPP-------------AIEGGDETSYFIV 1746
Query: 371 LEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQP----SDPGVLELPRVQVEHEGEFTCH 426
+ L L C SPP + W + GQ++ + L + + QV + G + C
Sbjct: 1747 MVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCM 1806
Query: 427 ARHPLGSQHVSLSLSVHYSPKLLGPSCSWEA----EGLHCSCSSQASPAPSLRWWLGEEL 482
A + G ++VH P + S + + C + P PS+ W ++
Sbjct: 1807 AANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQP 1866
Query: 483 LEGNSSQDSFEVTPS 497
+ N++Q + ++ S
Sbjct: 1867 V--NTAQGNLKIQSS 1879
Score = 39.3 bits (90), Expect = 0.012
Identities = 82/405 (20%), Positives = 139/405 (34%), Gaps = 61/405 (15%)
Query: 100 NCSLVIRDAQMQDESQYFFRV--ERGSYVRYNFMNDGFFLKVTALTQKPDVYIPETLEPG 157
N SL ++ + D +Y V E GS F+ KVT + + ++ G
Sbjct: 573 NLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKN------QSFTGG 626
Query: 158 QPVTVICVFNWAFEECPPPSFSWTGAALSSQGTKPTTSHFSVLSFTPRPQDHNTDLTCHV 217
V+++C + P P +WT + G+ F + + +
Sbjct: 627 SEVSIMC----SATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCL 682
Query: 218 DFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCA 277
+ G Q + LR AP+ +V+ L G + C
Sbjct: 683 ASNSAGTDKQNST-LRYIEAPKLMVVQSE-----------------LLVALGDITVMECK 724
Query: 278 ADSQPPATLSWVLQNRVLSSSHPWGPRPLG--LELPGVKAGDSGRYTCRAENRLGSQQRA 335
PP + W + L S PL L++ + D+G YTC A N G
Sbjct: 725 TSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGK 784
Query: 336 LDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPARLSWTQR 395
+ L V PP + Q V +G+ +LP C P + W +
Sbjct: 785 ITLDVGSPP-----VFIQEPADVSMEIGSNVTLP----------CYVQGYPEPTIKWRRL 829
Query: 396 GQVLSPSQPSD--------PGVLELPRVQVEHEGEFTCHARHPLG--SQHVSLSLSVHYS 445
+ S+P G L + + +G + C A + G +++++ +
Sbjct: 830 DNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVA 889
Query: 446 PKL-LGPSCSWEAEG--LHCSCSSQA-SPAPSLRWWLGEELLEGN 486
P + + PS + EG L C+ A +P P RW +L N
Sbjct: 890 PLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQN 934
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 90.1 bits (222), Expect = 6e-18
Identities = 91/329 (27%), Positives = 135/329 (41%), Gaps = 48/329 (14%)
Query: 156 PGQPVTVICVFNWAFEECPPPSFSWTGAALSSQGTKPTTSHFSVLSFT-PRPQDHNTDLT 214
PG+ VT++C + PP SW L ++ T H S + + Q + +
Sbjct: 2136 PGELVTMVCPVRGS----PPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIF 2191
Query: 215 CHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEP-QPQGNVPYLEAQKGQFLR 273
V S GV A R L+V P LEP + Q +V + +G +
Sbjct: 2192 TCVAASPAGV-ADRNFTLQVQVPP-------------VLEPVEFQNDVVVV---RGSLVE 2234
Query: 274 LLCAADSQPPATLSWVLQNR-VLSSSHPWGPRPLGLELPGVKAGDSGRYTCRAENRLGSQ 332
L C A P +SW+ +LS S GP L+L V AGDSG Y+C A + G
Sbjct: 2235 LPCEARGVPLPLVSWMKDGEPLLSQSLEQGP---SLQLEAVGAGDSGTYSCVAVSEAGEA 2291
Query: 333 QRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPARLSW 392
+R L+V PP +E+ G T L + G + L+C +P ++W
Sbjct: 2292 RRHFQLTVMEPPH-------------IEDSGQPTELSLTPGAPMELLCDAQGTPQPNITW 2338
Query: 393 TQRGQVLSPSQPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHYSPKLLGPS 452
+ GQ L+ + + L +V G +TC A P G+ S + V P ++GP
Sbjct: 2339 HKDGQALTRLENNSRATRVL---RVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPR 2395
Query: 453 CSWEAEGLH-----CSCSSQASPAPSLRW 476
GL CS +A PAP + W
Sbjct: 2396 GPRFVVGLAPGQLVLECSVEAEPAPKITW 2424
Score = 84.3 bits (207), Expect = 3e-16
Identities = 100/420 (23%), Positives = 157/420 (37%), Gaps = 76/420 (18%)
Query: 98 KGNCSLVIRDAQMQDESQYFFRVERGSYVRYNFMNDGFFLKVTALTQKPDVYIPETLE-- 155
+G L I++AQ+ D+ Y +V + G ++ LT V +P T E
Sbjct: 1892 RGGQRLEIQEAQVSDKGLYSCKVSNVA---------GEAVRTFTLT----VQVPPTFENP 1938
Query: 156 --------PGQPVTVICVFNWAFEECPPPSFSWTGAAL--SSQGTKPTTSHFSVLSFTPR 205
G P+ + C + P P+ +W + S S L +
Sbjct: 1939 KTETVSQVAGSPLVLTCDVSGV----PAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRL 1994
Query: 206 PQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEPQPQGNVPYLE 265
TC + ++ A++ + V APR ++R++
Sbjct: 1995 QPAQAGTYTCVAENTQ--AEARKDFVVAVLVAPRIRSSGVAREH---------------H 2037
Query: 266 AQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPL------GLELPGVKAGDSG 319
+GQ +RL C AD QPP ++W+ L GP L L G++A D+G
Sbjct: 2038 VLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQD--MGPHLRFYLDGGSLVLKGLRASDAG 2095
Query: 320 RYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLV 379
YTC A N G R ++V PP T+ + +L G+ + +V
Sbjct: 2096 AYTCVAHNPAGEDARLHTVNVLVPP------------TIKQGADGSGTLVSRPGELVTMV 2143
Query: 380 CVTHSSPPARLSWTQRGQVLSPSQPS----DPGVLELPRVQVEHEGEFTCHARHPLGSQH 435
C SPP +SW + G L SQ + L + +VQ+ G FTC A P G
Sbjct: 2144 CPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVAD 2203
Query: 436 VSLSLSVHYSPKLLGPSCSWEAEGLHCS-----CSSQASPAPSLRWWL-GEELLEGNSSQ 489
+ +L V P L + + S C ++ P P + W GE LL + Q
Sbjct: 2204 RNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQ 2263
Score = 83.6 bits (205), Expect = 6e-16
Identities = 97/365 (26%), Positives = 144/365 (39%), Gaps = 62/365 (16%)
Query: 148 VYIPETLEPGQPVTVICVFNWAFE-EC-----PPPSFSWTGAALSSQGTKPTTSHFSV-L 200
V +P +EPG PV + N + EC PPP SW +G +P +S V +
Sbjct: 691 VLVPPNIEPG-PVNKAVLENASVTLECLASGVPPPDVSWF------KGHQPVSSWMGVTV 743
Query: 201 SFTPR----PQDHNTDLTCH-VDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEP 255
S R Q +D + S S + LRV PR + P+L
Sbjct: 744 SVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITL-------PPSLPG 796
Query: 256 QPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWG----PRPLGLELP 311
N P +RL C A P TL W+ +S + G P L L
Sbjct: 797 PVLVNTP---------VRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLA 847
Query: 312 GVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVL 371
+A DSGRY+C A + +G ++ + L V PP L G ++ V+
Sbjct: 848 SARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSIL---------------GEELNVSVV 892
Query: 372 EGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQ----PSDPGVLELPRVQVEHEGEFTCHA 427
+S+ L C +H+ PP LSW + G+ L P +D +L++ R V G +TC A
Sbjct: 893 ANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEA 952
Query: 428 RHPLGSQHVSLSLSVHYSPKL-LGPSCSW---EAEGLHCSCSSQASPAPSLRWWLGEELL 483
+ G +L+V +P L S + E SC + P P + W + L
Sbjct: 953 LNQAGRSEKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPL 1012
Query: 484 EGNSS 488
G +
Sbjct: 1013 PGEGA 1017
Score = 81.6 bits (200), Expect = 2e-15
Identities = 74/292 (25%), Positives = 118/292 (40%), Gaps = 47/292 (16%)
Query: 272 LRLLCAADSQPPATLSWVLQNRVLSSS----HPWGPRPLGLELPGVKAGDSGRYTCRAEN 327
++LLC A P ++W +L +S + G R L +L ++ D+G YTC+A N
Sbjct: 329 VQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQL--QLGRAQSSDAGVYTCKASN 386
Query: 328 RLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPP 387
+G+ ++A L V PP T+ G + + G+ + L CV P
Sbjct: 387 AVGAAEKATRLDVYVPP------------TIEGAGGRPYVVKAVAGRPVALECVARGHPS 434
Query: 388 ARLSWTQRGQVLSPSQPS----DPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVH 443
LSW G ++ S S D VL L G ++C A P G + S+ V
Sbjct: 435 PTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQ 494
Query: 444 YSPKL-----LGPSCSWEAEGLHCSCSSQASPAPSLRWWLGEELLEGNSSQDSFEVTPSS 498
P+L LG + + L C + SP P+++W L G +++ V +S
Sbjct: 495 VPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQW-----LQNGRPAEELAGVQVAS 549
Query: 499 AGPWANSSLSLHGGLSSGLRLRCEAWN------------VHGAQSGSILQLP 538
G + H L C+A N VHG + +L++P
Sbjct: 550 QGTTLHID---HVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVP 598
Score = 79.7 bits (195), Expect = 8e-15
Identities = 74/278 (26%), Positives = 116/278 (41%), Gaps = 31/278 (11%)
Query: 254 EPQPQGNVP-YLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG--LEL 310
E + +G V Y E + L C ++ PP L+W +++ LS+ G L++
Sbjct: 1558 EEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQI 1617
Query: 311 PGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPV 370
P V+A ++GRY+C+A N +G +L V PP V++ V E N +S
Sbjct: 1618 PLVRAENAGRYSCKASNEVGEDWLHYELLVLTPP----VILGDTEELVEEVTVNASS--- 1670
Query: 371 LEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQP----SDPGVLELPRVQVEHEGEFTCH 426
++ L C +P +SW Q G SPS D VL++ +V + C
Sbjct: 1671 ----TVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCV 1726
Query: 427 ARHPLGSQHVSLSLSVHYSPKLLGPSCSWEAEGLHCS----CSSQASPAPSLRWW----- 477
A + GS +L V P++ G L+ S C A P P + W+
Sbjct: 1727 AENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQA 1786
Query: 478 --LGEE--LLEGNSSQDSFEVTPSSAGPWANSSLSLHG 511
LGEE LL G + S +G + +L+ G
Sbjct: 1787 LSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAG 1824
Score = 75.1 bits (183), Expect = 2e-13
Identities = 83/347 (23%), Positives = 143/347 (41%), Gaps = 42/347 (12%)
Query: 153 TLEPGQPVTVICVFNWAFEECPPPSFSWTGAALSSQGTK-----PTTSHFSVLSFTPRPQ 207
T+ P+++IC AF P P+ +W + ++ P T +L+ +
Sbjct: 1361 TVTVNNPISLICEA-LAF---PSPNITWMKDGAPFEASRNIQLLPGTHGLQILN---AQK 1413
Query: 208 DHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEPQPQGNVPYLEAQ 267
+ TC V + + A + + V P SIS+D +P + V ++ +
Sbjct: 1414 EDAGQYTCVV--TNELGEAVKNYHVEVLIPP-----SISKD-----DPLGEVGVKEVKTK 1461
Query: 268 KGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG--LELPGVKAGDSGRYTCRA 325
L L C + + PP T+ W + ++ S G L++ + DSGRY C A
Sbjct: 1462 VNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVA 1521
Query: 326 ENRLGSQQRALDLSVQYPPENLRVMVSQANRTVL----ENLGNGTSL-PVLEGQSLCLVC 380
N G + ++ +Q PP +V A +L E G T ++E L C
Sbjct: 1522 TNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYC 1581
Query: 381 VTHSSPPARLSWTQRGQVLSP----SQPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHV 436
T++ PP L+W + Q LS S VL++P V+ E+ G ++C A + +G +
Sbjct: 1582 DTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWL 1641
Query: 437 SLSLSVHYSPKLLGPSCSWEAE-------GLHCSCSSQASPAPSLRW 476
L V P +LG + E + C + +P P++ W
Sbjct: 1642 HYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISW 1688
Score = 73.6 bits (179), Expect = 6e-13
Identities = 85/361 (23%), Positives = 140/361 (38%), Gaps = 54/361 (14%)
Query: 148 VYIPETLEPGQPVTVICVFNWAFEEC-----PPPSFSWT--GAALSSQGTKPTTSHFSVL 200
V++P T+ Q + + C P P+ SW+ GA L ++G+ S L
Sbjct: 2662 VHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGAL 2721
Query: 201 SFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEPQPQGN 260
H TC + R A + + +++ +P ++P P
Sbjct: 2722 EIGQALPIHAGRYTC-------------SARNSAGVAHKHVFLTVQA--SPVVKPLPS-- 2764
Query: 261 VPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG-LELPGVKAGDSG 319
+ A + + L C A P T++W + +++ P G L + D+G
Sbjct: 2765 --VVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAG 2822
Query: 320 RYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLV 379
Y C A+N GS L VQ PP V+EN L EG L
Sbjct: 2823 NYLCIAKNSAGSAMGKTRLVVQVPP-------------VIEN--GLPDLSTTEGSHAFLP 2867
Query: 380 CVTHSSPPARLSWTQRGQVLSPS------QPSDPGVLELPRVQVEHEGEFTCHARHPLGS 433
C SP ++W + GQ +S + QPS G L + ++ + G +TC A + +G
Sbjct: 2868 CKARGSPEPNITWDKDGQPVSGAEGKFTIQPS--GELLVKNLEGQDAGTYTCTAENAVGR 2925
Query: 434 QHVSLSLSVHYSP---KLLGPSCSWEAEGLHCSCSSQASPAPSLRWWLGEE-LLEGNSSQ 489
+ L++ P L G + L C+++ SP P + W + + + EG S Q
Sbjct: 2926 ARRRVHLTILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQ 2985
Query: 490 D 490
D
Sbjct: 2986 D 2986
Score = 72.4 bits (176), Expect = 1e-12
Identities = 62/224 (27%), Positives = 90/224 (40%), Gaps = 42/224 (18%)
Query: 274 LLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLGLELPGVKA---------GDSGRYTCR 324
L C + + PP LSW R P PRP G+ L KA D+G YTC
Sbjct: 899 LECQSHAMPPPVLSWWKDGR------PLEPRP-GVHLSADKALLQVDRADVWDAGHYTCE 951
Query: 325 AENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHS 384
A N+ G ++ +L+V P + L +L V EG L C
Sbjct: 952 ALNQAGRSEKHYNLNVWVAP--------------VFPLRESHTLTVREGHPTSLSCECRG 997
Query: 385 SPPARLSWTQRGQVLSPSQPSDPGV------LELPRVQVEHEGEFTCHARHPLGSQHVSL 438
P ++SW + GQ L V L L + Q+ EG +TC + +G+ L
Sbjct: 998 VPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDL 1057
Query: 439 SLSVHYSPKLLGP-----SCSWEAEGL-HCSCSSQASPAPSLRW 476
L VH P++ GP S +G+ C++ P P++ W
Sbjct: 1058 QLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTW 1101
Score = 69.7 bits (169), Expect = 9e-12
Identities = 65/277 (23%), Positives = 109/277 (39%), Gaps = 47/277 (16%)
Query: 274 LLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLGLELPG---------VKAGDSGRYTCR 324
L C A +PP T++W + + + LGL+L +A +GRY+C
Sbjct: 1087 LECNATGKPPPTVTWERDGQPVGAE-------LGLQLQNQGQSLHVERAQAAHTGRYSCV 1139
Query: 325 AENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHS 384
AEN G +R +LSV PPE ++ +L T++ L L+C
Sbjct: 1140 AENLAGRAERKFELSVLVPPE------------LIGDLDPLTNITAALHSPLTLLCEAMG 1187
Query: 385 SPPARLSWTQRGQVLSPSQP----SDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSL 440
PP + W + + +SP + + +L++ + Q + G ++C A + G + S+
Sbjct: 1188 IPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSV 1247
Query: 441 SVHYSPKLLGPSCS-----WEAEGLHCSCSSQASPAPSLRWWL-GEELLEGNSSQDSFEV 494
V P + + + H C+ P P L W+ G L G D+ +
Sbjct: 1248 EVLVPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARG----DAHHI 1303
Query: 495 TPSSAGPWANSSLSLHGGLSSGLRLRCEAWNVHGAQS 531
+P L LSS C A N G ++
Sbjct: 1304 SPDGV-----LLQVLQANLSSAGHYSCIAANAVGEKT 1335
Score = 69.3 bits (168), Expect = 1e-11
Identities = 68/231 (29%), Positives = 98/231 (42%), Gaps = 27/231 (11%)
Query: 259 GNVPYL-EAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSH----PWGPRPLGLELPGV 313
G PY+ +A G+ + L C A P TLSW + ++ S+ L LE PG
Sbjct: 409 GGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPG- 467
Query: 314 KAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEG 373
SG Y+C A + G + VQ PP+ L V E LG T+ + G
Sbjct: 468 -EASSGLYSCVASSPAGEAVLQYSVEVQVPPQLL----------VAEGLGQVTT---IVG 513
Query: 374 QSLCLVCVTHSSPPARLSWTQRG---QVLSPSQPSDPG-VLELPRVQVEHEGEFTCHARH 429
Q L L C SP + W Q G + L+ Q + G L + V+++H G F C A +
Sbjct: 514 QPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATN 573
Query: 430 PLGSQHVSLSLSVH--YSPKLLG-PSCSWEAEGLHCSCSSQASPAPSLRWW 477
G+ + +SVH ++P +L P + H S A P R W
Sbjct: 574 EAGTAGAEVEVSVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGW 624
Score = 69.3 bits (168), Expect = 1e-11
Identities = 57/230 (24%), Positives = 91/230 (39%), Gaps = 23/230 (10%)
Query: 255 PQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSH-PWGPRPLG-LELPG 312
P + +P L +G L C A P ++W + +S + + +P G L +
Sbjct: 2847 PVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKN 2906
Query: 313 VKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLE 372
++ D+G YTC AEN +G +R + L++ P V L SL +
Sbjct: 2907 LEGQDAGTYTCTAENAVGRARRRVHLTILVLP-------------VFTTLPGDRSLRL-- 2951
Query: 373 GQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSDPGVLELPRVQVEHE--GEFTCHARHP 430
G L L C SP R+ WT + ++ G L R V E G + C A +
Sbjct: 2952 GDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENR 3011
Query: 431 LGSQHVSLSLSVHYSPKLLGPSCSWEAE----GLHCSCSSQASPAPSLRW 476
+G + V +P L G + S+ E + C + P P + W
Sbjct: 3012 VGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHW 3061
Score = 68.9 bits (167), Expect = 1e-11
Identities = 101/433 (23%), Positives = 159/433 (36%), Gaps = 79/433 (18%)
Query: 69 KGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFRVERGSYVRY 128
+G PVA +++SR + R + G+ + G S V + QY V+ V
Sbjct: 442 EGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQ----VPP 497
Query: 129 NFMNDGFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFEECPPPSFSWTGAALSSQ 188
+ +VT + +P + +P G PV I W + P+ G ++SQ
Sbjct: 498 QLLVAEGLGQVTTIVGQP-LELP-CQASGSPVPTI---QWL--QNGRPAEELAGVQVASQ 550
Query: 189 GTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISR- 247
GT H + DH+ C A+ V + +AP L + I +
Sbjct: 551 GTTLHIDHVEL--------DHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQY 602
Query: 248 -------DNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHP 300
+ PA P +G A +PP W S
Sbjct: 603 HWGXEHHSSFPAACDPP--------VHRG------WGAHPKPPLVEGW------CSPGSL 642
Query: 301 WG---------PRPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMV 351
WG P L++ V D G YTC A N G +R + L V PP +
Sbjct: 643 WGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPP---NIEP 699
Query: 352 SQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSP----SQPSDP 407
N+ VLEN S+ L C+ PP +SW + Q +S + D
Sbjct: 700 GPVNKAVLEN------------ASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDG 747
Query: 408 GVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHYSPKL-LGPSCSWEA---EGLHCS 463
VL + + Q+ G + C A + GS + L V+ P++ L PS + +
Sbjct: 748 RVLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLT 807
Query: 464 CSSQASPAPSLRW 476
C++ +P+P+L W
Sbjct: 808 CNATGAPSPTLMW 820
Score = 66.6 bits (161), Expect = 7e-11
Identities = 54/219 (24%), Positives = 91/219 (41%), Gaps = 27/219 (12%)
Query: 272 LRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG--LELPGVKAGDSGRYTCRAENRL 329
L LLC A PP + W +S G L++ + DSG Y+C A N
Sbjct: 1179 LTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEA 1238
Query: 330 GSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPAR 389
G +R + V PP +EN + VL+GQ+ L+C P +
Sbjct: 1239 GEARRNFSVEVLVPPS-------------IENEDLEEVIKVLDGQTAHLMCNVTGHPQPK 1285
Query: 390 LSWTQRGQVLSPSQ----PSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHYS 445
L+W + G+ L+ D +L++ + + G ++C A + +G + LSV +
Sbjct: 1286 LTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLA 1345
Query: 446 PKLLGPSCSWEAEGLHCS--------CSSQASPAPSLRW 476
P +LG + E + + C + A P+P++ W
Sbjct: 1346 PTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITW 1384
Score = 66.6 bits (161), Expect = 7e-11
Identities = 80/323 (24%), Positives = 122/323 (37%), Gaps = 48/323 (14%)
Query: 251 PALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLS--SSHPWGPRPLGL 308
P++E + V ++ GQ L+C P L+W R L+ +H P + L
Sbjct: 1253 PSIENEDLEEV--IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLL 1310
Query: 309 ELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSL 368
++ +G Y+C A N +G + + LSV P L A+ V + N S
Sbjct: 1311 QVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPIS- 1369
Query: 369 PVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSD--PGV--LELPRVQVEHEGEFT 424
L+C + P ++W + G S+ PG L++ Q E G++T
Sbjct: 1370 ---------LICEALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYT 1420
Query: 425 CHARHPLGSQHVSLSLSVHYSPKL-----LGPSCSWEAE-----GLHCSCSSQASPAPSL 474
C + LG + + V P + LG E + L C S A P P++
Sbjct: 1421 CVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTLECESWAVPPPTI 1480
Query: 475 RWWLGEELLEGNSSQDSFEVTPSSAGPWANSSLSLH---GGLSSGLRLRCEAWNVHGAQS 531
RW+ +D VTPSS L +S R C A NV G
Sbjct: 1481 RWY-----------KDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDD 1529
Query: 532 ---GSILQLP---DKKGLISTAF 548
++Q+P K G S AF
Sbjct: 1530 QDFNVLIQVPPMFQKVGDFSAAF 1552
Score = 65.9 bits (159), Expect = 1e-10
Identities = 62/223 (27%), Positives = 92/223 (41%), Gaps = 39/223 (17%)
Query: 274 LLCAADSQPPATLSWVLQNRVLSSSHPWGPRPL--------GLELPGVKAGDSGRYTCRA 325
L C A P T+SW LQN + P+ P P L++ + D+ Y C A
Sbjct: 1674 LQCPALGNPVPTISW-LQNGL-----PFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVA 1727
Query: 326 ENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSS 385
EN+ GS ++ L VQ PP + + Q V L + SLP C H+
Sbjct: 1728 ENQAGSAEKLFTLRVQVPPRIAGLDLEQ----VTAILNSSVSLP----------CDVHAH 1773
Query: 386 PPARLSWTQRGQVLSPSQPSD--PGV--LELPRVQVEHEGEFTCHARHPLGSQHVSLSLS 441
P ++W + Q LS + PG L+L R ++ G +TC A + G + LS
Sbjct: 1774 PNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLS 1833
Query: 442 VHYSPKLL----GPSCSW---EAEGLHCSCSSQASPAPSLRWW 477
V P GP + + SC + A P P++ W+
Sbjct: 1834 VLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWY 1876
Score = 65.9 bits (159), Expect = 1e-10
Identities = 84/357 (23%), Positives = 136/357 (38%), Gaps = 52/357 (14%)
Query: 153 TLEPGQPVTVICVFNWAFEECPPPSFSWTGAALSSQGTKPTTSHFSVLSFTPRPQDHNTD 212
+L PG P+ ++C + P P+ +W + + + VL R +D
Sbjct: 2315 SLTPGAPMELLC----DAQGTPQPNITWHKDGQALTRLENNSRATRVL----RVRDAGL- 2365
Query: 213 LTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEPQPQGNVPYLEAQKGQFL 272
TC + + +++ R+RV AP ++V P+G + GQ +
Sbjct: 2366 YTCLAESPAGAI--EKSFRVRVQ-APPNIV-------------GPRGPRFVVGLAPGQLV 2409
Query: 273 RLLCAADSQPPATLSWVLQNRVLSS-SHPWGP-RPLGLELPGVKAGDSGRYTCRAENRLG 330
L C+ +++P ++W VL +H P R L+L + DSG Y+C A N G
Sbjct: 2410 -LECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAG 2468
Query: 331 SQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPARL 390
S A + + P +R N +V Q+ L C P +
Sbjct: 2469 STSVAFRVEIHTVP-TIRSGPPAVNVSV--------------NQTALLPCQADGVPAPLV 2513
Query: 391 SWTQRGQVLSPSQPS----DPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHYSP 446
SW + L P P G L + V + G + C A + GS L V P
Sbjct: 2514 SWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRV-LEP 2572
Query: 447 KLLGPSCSWEAEGLH----CSCSSQASPAPSLRWWLGEELLEGNSSQDSFEVTPSSA 499
+ PS S H C + SP P + WW + L+ Q ++ + PS+A
Sbjct: 2573 PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNA 2629
Score = 65.1 bits (157), Expect = 2e-10
Identities = 83/358 (23%), Positives = 130/358 (36%), Gaps = 47/358 (13%)
Query: 136 FLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFEECPP-----PSFSW--TGAALSSQ 188
+L L P V + +T E + VTV + + CP P+ SW G S
Sbjct: 1640 WLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQ-CPALGNPVPTISWLQNGLPFSPS 1698
Query: 189 GTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRD 248
VL + C + + SA++ LRV PR + + +
Sbjct: 1699 PRLQVLEDGQVLQVSTAEVADAASYMCVAE--NQAGSAEKLFTLRVQVPPRIAGLDLEQ- 1755
Query: 249 NTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWG--PRPL 306
+ A + L C + P ++W ++ LS P
Sbjct: 1756 ---------------VTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTH 1800
Query: 307 GLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGT 366
L+L + DSG YTC A N G Q+ + LSV PP QA R G
Sbjct: 1801 TLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPP-----AFRQAPR------GPQD 1849
Query: 367 SLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSDP----GVLELPRVQVEHEGE 422
++ V G L C T + P ++W + GQ L +Q + LE+ QV +G
Sbjct: 1850 AVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGL 1909
Query: 423 FTCHARHPLGSQHVSLSLSVHYSPKLLGPSCSWEAE----GLHCSCSSQASPAPSLRW 476
++C + G + +L+V P P ++ L +C PAP++ W
Sbjct: 1910 YSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTW 1967
Score = 63.9 bits (154), Expect = 5e-10
Identities = 77/290 (26%), Positives = 107/290 (36%), Gaps = 44/290 (15%)
Query: 255 PQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPR----PLG-LE 309
P + P + Q L C AD P +SW L P PR P G L
Sbjct: 2482 PTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLD---PRSPRFEILPEGSLR 2538
Query: 310 LPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLP 369
+ V A D+G Y C A N GS ++ DL V PP + S +N T+ + P
Sbjct: 2539 IQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPP---AIAPSPSNLTLTAH------TP 2589
Query: 370 VLEGQSLCLVCVTHSSPPARLSWTQRGQVLS--------PSQPSDPGVLELPRVQVEHEG 421
L L C SP + W + GQ L PS+ +L P Q
Sbjct: 2590 AL------LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQ--DSA 2641
Query: 422 EFTCHARHPLGSQHVSLSLSVHYSPKLLGPSCSWEAEGLH---CSCSSQASPAPSLRWWL 478
+F C + +G H ++VH P + + + +C S PAP++ W
Sbjct: 2642 QFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSK 2701
Query: 479 GEELLEGNSSQDSFEVTPSSAGPWANSSLSLHGGLSSGLRLRCEAWNVHG 528
L S + V+PS A +L +H G R C A N G
Sbjct: 2702 AGAQLGARGS--GYRVSPSGALE-IGQALPIHAG-----RYTCSARNSAG 2743
Score = 62.0 bits (149), Expect = 2e-09
Identities = 49/184 (26%), Positives = 74/184 (40%), Gaps = 22/184 (11%)
Query: 308 LELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTS 367
L L + G YTC N +G+ + L L V PP+ + T
Sbjct: 1029 LYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQ------------IAGPREPPTQ 1076
Query: 368 LPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPS---QPSDPG-VLELPRVQVEHEGEF 423
+ V++ L C PP ++W + GQ + Q + G L + R Q H G +
Sbjct: 1077 VSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRY 1136
Query: 424 TCHARHPLGSQHVSLSLSVHYSPKLLG---PSCSWEA---EGLHCSCSSQASPAPSLRWW 477
+C A + G LSV P+L+G P + A L C + P P++RW+
Sbjct: 1137 SCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWF 1196
Query: 478 LGEE 481
GEE
Sbjct: 1197 RGEE 1200
Score = 57.8 bits (138), Expect = 3e-08
Identities = 59/238 (24%), Positives = 90/238 (37%), Gaps = 33/238 (13%)
Query: 269 GQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPR------PLGLELPGVKAGDSGRYT 322
G + L C P + W + + P GP L + G GD GRY
Sbjct: 232 GADVELQCWTSGVPTPQVEWTKDRQPVL---PGGPHLQVQEDGQVLRITGSHVGDEGRYQ 288
Query: 323 CRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVT 382
C A + G Q R L V PP + +N T + V+E + L+C
Sbjct: 289 CVAFSPAGQQARDFQLRVHAPP-----TIWGSNET--------GEVAVMEDHLVQLLCEA 335
Query: 383 HSSPPARLSWTQRGQVLSPS----QPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSL 438
P ++W + G +L S L+L R Q G +TC A + +G+ +
Sbjct: 336 RGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKAT 395
Query: 439 SLSVHYSPKLLG----PSCSWEAEG--LHCSCSSQASPAPSLRW-WLGEELLEGNSSQ 489
L V+ P + G P G + C ++ P+P+L W G + E N S+
Sbjct: 396 RLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESR 453
Score = 55.5 bits (132), Expect = 2e-07
Identities = 82/362 (22%), Positives = 129/362 (35%), Gaps = 66/362 (18%)
Query: 140 TALTQKPDVYIPETLEPGQPVTVICVFNWAFEEC-----PPPSFSWTGAALSSQGTKPTT 194
T++ + +++ T+ G P + V A C P P SW + P
Sbjct: 2470 TSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRF 2529
Query: 195 SHFSVLSFTPRP---QDHNTDLTCHVDFSRKGVSAQRTVRL----RVAYAPRDLVISISR 247
S +P QD L C S R +R+ +A +P +L ++
Sbjct: 2530 EILPEGSLRIQPVLAQDAGHYL-CLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTA-- 2586
Query: 248 DNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGP---- 303
+TPAL P C A P + W + L G
Sbjct: 2587 -HTPALLP--------------------CEASGSPKPLVVWWKDGQKLDFRLQQGAYRLL 2625
Query: 304 --RPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLEN 361
L L PG + DS ++ C N +G R ++V PP T+ ++
Sbjct: 2626 PSNALLLTAPGPQ--DSAQFECVVSNEVGEAHRLYQVTVHVPP------------TIADD 2671
Query: 362 LGNGTSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVL----SPSQPSDPGVLELPRVQV 417
T V + L C + P +SW++ G L S + S G LE+ +
Sbjct: 2672 Q---TDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALP 2728
Query: 418 EHEGEFTCHARHPLGSQHVSLSLSVHYSPKLLG-PSC--SWEAEGLHCSCSSQASPAPSL 474
H G +TC AR+ G H + L+V SP + PS + E + C + P P++
Sbjct: 2729 IHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTI 2788
Query: 475 RW 476
W
Sbjct: 2789 TW 2790
Score = 54.7 bits (130), Expect = 3e-07
Identities = 50/189 (26%), Positives = 70/189 (37%), Gaps = 19/189 (10%)
Query: 263 YLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG-LELPGVKAGDSGRY 321
YL G ++L C P + W+ L SH G L + + D+GRY
Sbjct: 3036 YLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRY 3095
Query: 322 TCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCV 381
C AEN +G ++ + L +Q P V Q + V G + L C
Sbjct: 3096 QCLAENEMGVAKKVVILVLQSAP------VFQV---------EPQDMTVRSGDDVALRCQ 3140
Query: 382 THSSPPARLSWTQRGQVLSPS---QPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSL 438
P + W Q GQ L S + G L L V+ G + C A + LGS
Sbjct: 3141 ATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARA 3200
Query: 439 SLSVHYSPK 447
L V P+
Sbjct: 3201 FLVVRGEPQ 3209
Score = 51.6 bits (122), Expect = 2e-06
Identities = 63/257 (24%), Positives = 95/257 (36%), Gaps = 37/257 (14%)
Query: 259 GNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPW-------------GPRP 305
G + GQ L L C A+ P + W+ +++ W G R
Sbjct: 101 GRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRL 160
Query: 306 L----GLELPGVKAGDSGRYTCRAENRLGSQQ---RALDLSVQYPPENLRVMVSQANRTV 358
L L P ++ G SGR +A ++ L Q+P + A +V
Sbjct: 161 LDEGQSLHFPRIQPGRSGRRGAQAGGSAQTKAPWXAGLAGFEQFPTPH--AFSPPAPPSV 218
Query: 359 LENLGNGTSLPVL--EGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQP-----SDPGVLE 411
L G G + VL G + L C T P ++ WT+ Q + P P D VL
Sbjct: 219 L---GAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLR 275
Query: 412 LPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHYSPKLLGPSCSWEAEGL-----HCSCSS 466
+ V EG + C A P G Q L VH P + G + + E + C +
Sbjct: 276 ITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEA 335
Query: 467 QASPAPSLRWWLGEELL 483
+ P P++ W+ LL
Sbjct: 336 RGVPTPNITWFKDGALL 352
Score = 47.0 bits (110), Expect = 6e-05
Identities = 31/105 (29%), Positives = 48/105 (45%), Gaps = 5/105 (4%)
Query: 242 VISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPW 301
V+ + + P + +PQ + + G + L C A +P T+ W+ + L +S
Sbjct: 3109 VVILVLQSAPVFQVEPQD----MTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRL 3164
Query: 302 GPRPLG-LELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPE 345
P G L L V+ GD+G Y C A N LGS L V+ P+
Sbjct: 3165 RTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQ 3209
Score = 43.1 bits (100), Expect = 9e-04
Identities = 35/131 (26%), Positives = 49/131 (37%), Gaps = 24/131 (18%)
Query: 276 CAADSQPPATLSWVLQNRVLSSSHPWGPRPL-------GLELPGVKAGDSGRYTCRAENR 328
C P ++W R SS P +P L L V DSG Y C+A N
Sbjct: 24 CGTHGTPKPQVTW----RKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQATNE 79
Query: 329 LGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPA 388
+GS R L V PP + G ++ + GQSL L C + P
Sbjct: 80 VGSTSRRAKLVVYVPPS-------------IREDGRKANVSGMAGQSLTLECDANGFPVP 126
Query: 389 RLSWTQRGQVL 399
+ W + Q++
Sbjct: 127 EIVWLKDAQLV 137
Score = 37.7 bits (86), Expect = 0.036
Identities = 43/180 (23%), Positives = 63/180 (35%), Gaps = 37/180 (20%)
Query: 380 CVTHSSPPARLSWTQRGQVLSP--SQPS----DPGVLELPRVQVEHEGEFTCHARHPLGS 433
C TH +P +++W ++G P QP + G L L V G++ C A + +GS
Sbjct: 24 CGTHGTPKPQVTW-RKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVGS 82
Query: 434 QHVSLSLSVHYSPKLLGPSCSWEAEG-----LHCSCSSQASPAPSLRWWLGEELLEGNSS 488
L V+ P + G L C + P P + W +L+
Sbjct: 83 TSRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVG---- 138
Query: 489 QDSFEVTPSSAGPWANSSLSLHGGLSSGLRLRCEAWNVH------------GAQSGSILQ 536
P WA L G G RL E ++H GAQ+G Q
Sbjct: 139 ------VPLG---WAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQPGRSGRRGAQAGGSAQ 189
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 90.1 bits (222), Expect = 6e-18
Identities = 91/329 (27%), Positives = 135/329 (41%), Gaps = 48/329 (14%)
Query: 156 PGQPVTVICVFNWAFEECPPPSFSWTGAALSSQGTKPTTSHFSVLSFT-PRPQDHNTDLT 214
PG+ VT++C + PP SW L ++ T H S + + Q + +
Sbjct: 3327 PGELVTMVCPVRGS----PPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIF 3382
Query: 215 CHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEP-QPQGNVPYLEAQKGQFLR 273
V S GV A R L+V P LEP + Q +V + +G +
Sbjct: 3383 TCVAASPAGV-ADRNFTLQVQVPP-------------VLEPVEFQNDVVVV---RGSLVE 3425
Query: 274 LLCAADSQPPATLSWVLQNR-VLSSSHPWGPRPLGLELPGVKAGDSGRYTCRAENRLGSQ 332
L C A P +SW+ +LS S GP L+L V AGDSG Y+C A + G
Sbjct: 3426 LPCEARGVPLPLVSWMKDGEPLLSQSLEQGP---SLQLEAVGAGDSGTYSCVAVSEAGEA 3482
Query: 333 QRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPARLSW 392
+R L+V PP +E+ G T L + G + L+C +P ++W
Sbjct: 3483 RRHFQLTVMEPPH-------------IEDSGQPTELSLTPGAPMELLCDAQGTPQPNITW 3529
Query: 393 TQRGQVLSPSQPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHYSPKLLGPS 452
+ GQ L+ + + L +V G +TC A P G+ S + V P ++GP
Sbjct: 3530 HKDGQALTRLENNSRATRVL---RVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPR 3586
Query: 453 CSWEAEGLH-----CSCSSQASPAPSLRW 476
GL CS +A PAP + W
Sbjct: 3587 GPRFVVGLAPGQLVLECSVEAEPAPKITW 3615
Score = 84.3 bits (207), Expect = 3e-16
Identities = 100/420 (23%), Positives = 157/420 (37%), Gaps = 76/420 (18%)
Query: 98 KGNCSLVIRDAQMQDESQYFFRVERGSYVRYNFMNDGFFLKVTALTQKPDVYIPETLE-- 155
+G L I++AQ+ D+ Y +V + G ++ LT V +P T E
Sbjct: 3083 RGGQRLEIQEAQVSDKGLYSCKVSNVA---------GEAVRTFTLT----VQVPPTFENP 3129
Query: 156 --------PGQPVTVICVFNWAFEECPPPSFSWTGAAL--SSQGTKPTTSHFSVLSFTPR 205
G P+ + C + P P+ +W + S S L +
Sbjct: 3130 KTETVSQVAGSPLVLTCDVSGV----PAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRL 3185
Query: 206 PQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEPQPQGNVPYLE 265
TC + ++ A++ + V APR ++R++
Sbjct: 3186 QPAQAGTYTCVAENTQ--AEARKDFVVAVLVAPRIRSSGVAREH---------------H 3228
Query: 266 AQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPL------GLELPGVKAGDSG 319
+GQ +RL C AD QPP ++W+ L GP L L G++A D+G
Sbjct: 3229 VLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQD--MGPHLRFYLDGGSLVLKGLRASDAG 3286
Query: 320 RYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLV 379
YTC A N G R ++V PP T+ + +L G+ + +V
Sbjct: 3287 AYTCVAHNPAGEDARLHTVNVLVPP------------TIKQGADGSGTLVSRPGELVTMV 3334
Query: 380 CVTHSSPPARLSWTQRGQVLSPSQPS----DPGVLELPRVQVEHEGEFTCHARHPLGSQH 435
C SPP +SW + G L SQ + L + +VQ+ G FTC A P G
Sbjct: 3335 CPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVAD 3394
Query: 436 VSLSLSVHYSPKLLGPSCSWEAEGLHCS-----CSSQASPAPSLRWWL-GEELLEGNSSQ 489
+ +L V P L + + S C ++ P P + W GE LL + Q
Sbjct: 3395 RNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQ 3454
Score = 83.6 bits (205), Expect = 6e-16
Identities = 97/365 (26%), Positives = 144/365 (39%), Gaps = 62/365 (16%)
Query: 148 VYIPETLEPGQPVTVICVFNWAFE-EC-----PPPSFSWTGAALSSQGTKPTTSHFSV-L 200
V +P +EPG PV + N + EC PPP SW +G +P +S V +
Sbjct: 1882 VLVPPNIEPG-PVNKAVLENASVTLECLASGVPPPDVSWF------KGHQPVSSWMGVTV 1934
Query: 201 SFTPR----PQDHNTDLTCH-VDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEP 255
S R Q +D + S S + LRV PR + P+L
Sbjct: 1935 SVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITL-------PPSLPG 1987
Query: 256 QPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWG----PRPLGLELP 311
N P +RL C A P TL W+ +S + G P L L
Sbjct: 1988 PVLVNTP---------VRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLA 2038
Query: 312 GVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVL 371
+A DSGRY+C A + +G ++ + L V PP L G ++ V+
Sbjct: 2039 SARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSIL---------------GEELNVSVV 2083
Query: 372 EGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQ----PSDPGVLELPRVQVEHEGEFTCHA 427
+S+ L C +H+ PP LSW + G+ L P +D +L++ R V G +TC A
Sbjct: 2084 ANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEA 2143
Query: 428 RHPLGSQHVSLSLSVHYSPKL-LGPSCSW---EAEGLHCSCSSQASPAPSLRWWLGEELL 483
+ G +L+V +P L S + E SC + P P + W + L
Sbjct: 2144 LNQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPL 2203
Query: 484 EGNSS 488
G +
Sbjct: 2204 PGEGA 2208
Score = 82.4 bits (202), Expect = 1e-15
Identities = 71/252 (28%), Positives = 100/252 (39%), Gaps = 40/252 (15%)
Query: 259 GNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPW-------------GPRP 305
G + GQ L L C A+ P + W+ +++ W G R
Sbjct: 1305 GRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRL 1364
Query: 306 L----GLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLEN 361
L L P ++ GDSG Y+CRAEN+ G+ QR L V PP L +Q E
Sbjct: 1365 LDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQ------EV 1418
Query: 362 LGNGTSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQP-----SDPGVLELPRVQ 416
LG L G + L C T P ++ WT+ Q + P P D VL +
Sbjct: 1419 LG-------LAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQVLRITGSH 1471
Query: 417 VEHEGEFTCHARHPLGSQHVSLSLSVHYSPKLLGPSCSWEAEGL-----HCSCSSQASPA 471
V EG + C A P G Q L VH P + G + + E + C ++ P
Sbjct: 1472 VGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPT 1531
Query: 472 PSLRWWLGEELL 483
P++ W+ LL
Sbjct: 1532 PNITWFKDGALL 1543
Score = 81.6 bits (200), Expect = 2e-15
Identities = 74/292 (25%), Positives = 118/292 (40%), Gaps = 47/292 (16%)
Query: 272 LRLLCAADSQPPATLSWVLQNRVLSSS----HPWGPRPLGLELPGVKAGDSGRYTCRAEN 327
++LLC A P ++W +L +S + G R L +L ++ D+G YTC+A N
Sbjct: 1520 VQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQL--QLGRAQSSDAGVYTCKASN 1577
Query: 328 RLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPP 387
+G+ ++A L V PP T+ G + + G+ + L CV P
Sbjct: 1578 AVGAAEKATRLDVYVPP------------TIEGAGGRPYVVKAVAGRPVALECVARGHPS 1625
Query: 388 ARLSWTQRGQVLSPSQPS----DPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVH 443
LSW G ++ S S D VL L G ++C A P G + S+ V
Sbjct: 1626 PTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQ 1685
Query: 444 YSPKL-----LGPSCSWEAEGLHCSCSSQASPAPSLRWWLGEELLEGNSSQDSFEVTPSS 498
P+L LG + + L C + SP P+++W L G +++ V +S
Sbjct: 1686 VPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQW-----LQNGRPAEELAGVQVAS 1740
Query: 499 AGPWANSSLSLHGGLSSGLRLRCEAWN------------VHGAQSGSILQLP 538
G + H L C+A N VHG + +L++P
Sbjct: 1741 QGTTLHID---HVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVP 1789
Score = 81.3 bits (199), Expect = 3e-15
Identities = 73/273 (26%), Positives = 115/273 (42%), Gaps = 37/273 (13%)
Query: 268 KGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG-LELPGVKAGDSGRYTCRAE 326
+G +++ C+A P +SW +++ L G L + GV D+G Y+C+A
Sbjct: 621 QGVEVKVSCSASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQAT 680
Query: 327 NRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSP 386
N +G+ Q + L PP VS N VL V G+ LVC P
Sbjct: 681 NEVGTDQETVTLYYTDPPS-----VSAVNAVVL----------VAVGEEAVLVCEASGVP 725
Query: 387 PARLSWTQRG--QVLSPSQPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHY 444
P R+ W + G +L+P + S G L +P Q G +TC A + LG + L+V +
Sbjct: 726 PPRVIWYRGGLEMILAP-EGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGH 784
Query: 445 SPKL--LGPSCSWE-AEGLHCSCSSQASPAPSLRWW------LGEELLEGNSSQDS---- 491
+P+L L + E +C + P P++ W LG L G S+
Sbjct: 785 APQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDS 844
Query: 492 ----FE-VTPSSAGPWANSSLSLHGGLSSGLRL 519
FE V P P+ + ++ G + + RL
Sbjct: 845 GVLFFESVAPEDQAPYVCEARNVFGKVQAEARL 877
Score = 79.7 bits (195), Expect = 8e-15
Identities = 74/278 (26%), Positives = 116/278 (41%), Gaps = 31/278 (11%)
Query: 254 EPQPQGNVP-YLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG--LEL 310
E + +G V Y E + L C ++ PP L+W +++ LS+ G L++
Sbjct: 2749 EEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQI 2808
Query: 311 PGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPV 370
P V+A ++GRY+C+A N +G +L V PP V++ V E N +S
Sbjct: 2809 PLVRAENAGRYSCKASNEVGEDWLHYELLVLTPP----VILGDTEELVEEVTVNASS--- 2861
Query: 371 LEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQP----SDPGVLELPRVQVEHEGEFTCH 426
++ L C +P +SW Q G SPS D VL++ +V + C
Sbjct: 2862 ----TVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCV 2917
Query: 427 ARHPLGSQHVSLSLSVHYSPKLLGPSCSWEAEGLHCS----CSSQASPAPSLRWW----- 477
A + GS +L V P++ G L+ S C A P P + W+
Sbjct: 2918 AENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQA 2977
Query: 478 --LGEE--LLEGNSSQDSFEVTPSSAGPWANSSLSLHG 511
LGEE LL G + S +G + +L+ G
Sbjct: 2978 LSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAG 3015
Score = 75.1 bits (183), Expect = 2e-13
Identities = 95/366 (25%), Positives = 126/366 (34%), Gaps = 76/366 (20%)
Query: 148 VYIPETLEPGQPVTVICV-----FNWAFEECPPPSFSWTGAALSSQGTKPTTS-HFSVLS 201
V +P ++PG V + V N E P P SW+ + QG P S HF+ +
Sbjct: 1116 VQVPPQVQPGPRVLKVLVGEALDLNCVAEGNPEPQLSWSKDGVVLQGRGPQGSVHFAAI- 1174
Query: 202 FTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEPQPQGNV 261
R D C S GV A V LRV P D T L
Sbjct: 1175 ---RTSDAGR-YRCEASNSA-GVDAWE-VELRVLEPPH-----WGADETSGL-------- 1215
Query: 262 PYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPL-------GLELPGVK 314
LE G+ L C A P ++W R SS P +P L L V
Sbjct: 1216 --LERVAGENASLPCPARGTPKPQVTW----RKGPSSEPLHGQPGVAVLEEGSLFLASVS 1269
Query: 315 AGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQ 374
DSG Y C+A N +GS R L V PP + G ++ + GQ
Sbjct: 1270 PADSGDYECQATNEVGSTSRRAKLVVYVPPS-------------IREDGRKANVSGMAGQ 1316
Query: 375 SLCLVCVTHSSPPARLSWTQR-------------------GQVLSPSQPSDPGVLELPRV 415
SL L C + P + W + GQV + L PR+
Sbjct: 1317 SLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRI 1376
Query: 416 QVEHEGEFTCHARHPLGSQHVSLSLSVHYSPKLLGPSCSWEAEGL-----HCSCSSQASP 470
Q G ++C A + G+ L V P +LG + E GL C + P
Sbjct: 1377 QEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQEVLGLAGADVELQCWTSGVP 1436
Query: 471 APSLRW 476
P + W
Sbjct: 1437 TPQVEW 1442
Score = 75.1 bits (183), Expect = 2e-13
Identities = 83/347 (23%), Positives = 143/347 (41%), Gaps = 42/347 (12%)
Query: 153 TLEPGQPVTVICVFNWAFEECPPPSFSWTGAALSSQGTK-----PTTSHFSVLSFTPRPQ 207
T+ P+++IC AF P P+ +W + ++ P T +L+ +
Sbjct: 2552 TVTVNNPISLICEA-LAF---PSPNITWMKDGAPFEASRNIQLLPGTHGLQILN---AQK 2604
Query: 208 DHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEPQPQGNVPYLEAQ 267
+ TC V + + A + + V P SIS+D +P + V ++ +
Sbjct: 2605 EDAGQYTCVV--TNELGEAVKNYHVEVLIPP-----SISKD-----DPLGEVGVKEVKTK 2652
Query: 268 KGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG--LELPGVKAGDSGRYTCRA 325
L L C + + PP T+ W + ++ S G L++ + DSGRY C A
Sbjct: 2653 VNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVA 2712
Query: 326 ENRLGSQQRALDLSVQYPPENLRVMVSQANRTVL----ENLGNGTSL-PVLEGQSLCLVC 380
N G + ++ +Q PP +V A +L E G T ++E L C
Sbjct: 2713 TNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYC 2772
Query: 381 VTHSSPPARLSWTQRGQVLSP----SQPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHV 436
T++ PP L+W + Q LS S VL++P V+ E+ G ++C A + +G +
Sbjct: 2773 DTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWL 2832
Query: 437 SLSLSVHYSPKLLGPSCSWEAE-------GLHCSCSSQASPAPSLRW 476
L V P +LG + E + C + +P P++ W
Sbjct: 2833 HYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISW 2879
Score = 73.6 bits (179), Expect = 6e-13
Identities = 85/361 (23%), Positives = 140/361 (38%), Gaps = 54/361 (14%)
Query: 148 VYIPETLEPGQPVTVICVFNWAFEEC-----PPPSFSWT--GAALSSQGTKPTTSHFSVL 200
V++P T+ Q + + C P P+ SW+ GA L ++G+ S L
Sbjct: 3853 VHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGAL 3912
Query: 201 SFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEPQPQGN 260
H TC + R A + + +++ +P ++P P
Sbjct: 3913 EIGQALPIHAGRYTC-------------SARNSAGVAHKHVFLTVQA--SPVVKPLPS-- 3955
Query: 261 VPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG-LELPGVKAGDSG 319
+ A + + L C A P T++W + +++ P G L + D+G
Sbjct: 3956 --VVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAG 4013
Query: 320 RYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLV 379
Y C A+N GS L VQ PP V+EN L EG L
Sbjct: 4014 NYLCIAKNSAGSAMGKTRLVVQVPP-------------VIEN--GLPDLSTTEGSHAFLP 4058
Query: 380 CVTHSSPPARLSWTQRGQVLSPS------QPSDPGVLELPRVQVEHEGEFTCHARHPLGS 433
C SP ++W + GQ +S + QPS G L + ++ + G +TC A + +G
Sbjct: 4059 CKARGSPEPNITWDKDGQPVSGAEGKFTIQPS--GELLVKNLEGQDAGTYTCTAENAVGR 4116
Query: 434 QHVSLSLSVHYSP---KLLGPSCSWEAEGLHCSCSSQASPAPSLRWWLGEE-LLEGNSSQ 489
+ L++ P L G + L C+++ SP P + W + + + EG S Q
Sbjct: 4117 ARRRVHLTILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQ 4176
Query: 490 D 490
D
Sbjct: 4177 D 4177
Score = 72.4 bits (176), Expect = 1e-12
Identities = 62/224 (27%), Positives = 90/224 (40%), Gaps = 42/224 (18%)
Query: 274 LLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLGLELPGVKA---------GDSGRYTCR 324
L C + + PP LSW R P PRP G+ L KA D+G YTC
Sbjct: 2090 LECQSHAMPPPVLSWWKDGR------PLEPRP-GVHLSADKALLQVDRADVWDAGHYTCE 2142
Query: 325 AENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHS 384
A N+ G ++ +L+V P + L +L V EG L C
Sbjct: 2143 ALNQAGHSEKHYNLNVWVAP--------------VFPLRESHTLTVREGHPTSLSCECRG 2188
Query: 385 SPPARLSWTQRGQVLSPSQPSDPGV------LELPRVQVEHEGEFTCHARHPLGSQHVSL 438
P ++SW + GQ L V L L + Q+ EG +TC + +G+ L
Sbjct: 2189 VPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDL 2248
Query: 439 SLSVHYSPKLLGP-----SCSWEAEGL-HCSCSSQASPAPSLRW 476
L VH P++ GP S +G+ C++ P P++ W
Sbjct: 2249 QLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTW 2292
Score = 70.1 bits (170), Expect = 7e-12
Identities = 68/247 (27%), Positives = 95/247 (38%), Gaps = 36/247 (14%)
Query: 292 NRVLSSSHPW---GPRPLG-LELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENL 347
NR+ S + W G P G L L V+ GDSG Y C A N GS L VQ PP+
Sbjct: 1064 NRLALSKYVWEEYGLLPSGSLRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQVPPQ-- 1121
Query: 348 RVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSDP 407
V R L VL G++L L CV +P +LSW++ G VL P
Sbjct: 1122 ---VQPGPRV----------LKVLVGEALDLNCVAEGNPEPQLSWSKDGVVLQGRGPQ-- 1166
Query: 408 GVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHYSPKLLGPSCSW-----EAEGLHC 462
G + ++ G + C A + G + L V P S E
Sbjct: 1167 GSVHFAAIRTSDAGRYRCEASNSAGVDAWEVELRVLEPPHWGADETSGLLERVAGENASL 1226
Query: 463 SCSSQASPAPSLRWWLG--EELLEGNSSQDSFE--------VTPSSAGPWANSSLSLHGG 512
C ++ +P P + W G E L G E V+P+ +G + + + G
Sbjct: 1227 PCPARGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVGS 1286
Query: 513 LSSGLRL 519
S +L
Sbjct: 1287 TSRRAKL 1293
Score = 69.7 bits (169), Expect = 9e-12
Identities = 65/277 (23%), Positives = 109/277 (39%), Gaps = 47/277 (16%)
Query: 274 LLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLGLELPG---------VKAGDSGRYTCR 324
L C A +PP T++W + + + LGL+L +A +GRY+C
Sbjct: 2278 LECNATGKPPPTVTWERDGQPVGAE-------LGLQLQNQGQSLHVERAQAAHTGRYSCV 2330
Query: 325 AENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHS 384
AEN G +R +LSV PPE ++ +L T++ L L+C
Sbjct: 2331 AENLAGRAERKFELSVLVPPE------------LIGDLDPLTNITAALHSPLTLLCEAMG 2378
Query: 385 SPPARLSWTQRGQVLSPSQP----SDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSL 440
PP + W + + +SP + + +L++ + Q + G ++C A + G + S+
Sbjct: 2379 IPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSV 2438
Query: 441 SVHYSPKLLGPSCS-----WEAEGLHCSCSSQASPAPSLRWWL-GEELLEGNSSQDSFEV 494
V P + + + H C+ P P L W+ G L G D+ +
Sbjct: 2439 EVLVPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARG----DAHHI 2494
Query: 495 TPSSAGPWANSSLSLHGGLSSGLRLRCEAWNVHGAQS 531
+P L LSS C A N G ++
Sbjct: 2495 SPDGV-----LLQVLQANLSSAGHYSCIAANAVGEKT 2526
Score = 69.3 bits (168), Expect = 1e-11
Identities = 68/231 (29%), Positives = 98/231 (42%), Gaps = 27/231 (11%)
Query: 259 GNVPYL-EAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSH----PWGPRPLGLELPGV 313
G PY+ +A G+ + L C A P TLSW + ++ S+ L LE PG
Sbjct: 1600 GGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPG- 1658
Query: 314 KAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEG 373
SG Y+C A + G + VQ PP+ L V E LG T+ + G
Sbjct: 1659 -EASSGLYSCVASSPAGEAVLQYSVEVQVPPQLL----------VAEGLGQVTT---IVG 1704
Query: 374 QSLCLVCVTHSSPPARLSWTQRG---QVLSPSQPSDPG-VLELPRVQVEHEGEFTCHARH 429
Q L L C SP + W Q G + L+ Q + G L + V+++H G F C A +
Sbjct: 1705 QPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATN 1764
Query: 430 PLGSQHVSLSLSVH--YSPKLLG-PSCSWEAEGLHCSCSSQASPAPSLRWW 477
G+ + +SVH ++P +L P + H S A P R W
Sbjct: 1765 EAGTAGAEVEVSVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGW 1815
Score = 69.3 bits (168), Expect = 1e-11
Identities = 57/230 (24%), Positives = 91/230 (39%), Gaps = 23/230 (10%)
Query: 255 PQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSH-PWGPRPLG-LELPG 312
P + +P L +G L C A P ++W + +S + + +P G L +
Sbjct: 4038 PVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKN 4097
Query: 313 VKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLE 372
++ D+G YTC AEN +G +R + L++ P V L SL +
Sbjct: 4098 LEGQDAGTYTCTAENAVGRARRRVHLTILVLP-------------VFTTLPGDRSLRL-- 4142
Query: 373 GQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSDPGVLELPRVQVEHE--GEFTCHARHP 430
G L L C SP R+ WT + ++ G L R V E G + C A +
Sbjct: 4143 GDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENR 4202
Query: 431 LGSQHVSLSLSVHYSPKLLGPSCSWEAE----GLHCSCSSQASPAPSLRW 476
+G + V +P L G + S+ E + C + P P + W
Sbjct: 4203 VGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHW 4252
Score = 68.9 bits (167), Expect = 1e-11
Identities = 101/433 (23%), Positives = 159/433 (36%), Gaps = 79/433 (18%)
Query: 69 KGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFRVERGSYVRY 128
+G PVA +++SR + R + G+ + G S V + QY V+ V
Sbjct: 1633 EGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQ----VPP 1688
Query: 129 NFMNDGFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFEECPPPSFSWTGAALSSQ 188
+ +VT + +P + +P G PV I W + P+ G ++SQ
Sbjct: 1689 QLLVAEGLGQVTTIVGQP-LELP-CQASGSPVPTI---QWL--QNGRPAEELAGVQVASQ 1741
Query: 189 GTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISR- 247
GT H + DH+ C A+ V + +AP L + I +
Sbjct: 1742 GTTLHIDHVEL--------DHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQY 1793
Query: 248 -------DNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHP 300
+ PA P +G A +PP W S
Sbjct: 1794 HWGXEHHSSFPAACDPP--------VHRG------WGAHPKPPLVEGW------CSPGSL 1833
Query: 301 WG---------PRPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMV 351
WG P L++ V D G YTC A N G +R + L V PP +
Sbjct: 1834 WGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPP---NIEP 1890
Query: 352 SQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSP----SQPSDP 407
N+ VLEN S+ L C+ PP +SW + Q +S + D
Sbjct: 1891 GPVNKAVLEN------------ASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDG 1938
Query: 408 GVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHYSPKL-LGPSCSWEA---EGLHCS 463
VL + + Q+ G + C A + GS + L V+ P++ L PS + +
Sbjct: 1939 RVLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLT 1998
Query: 464 CSSQASPAPSLRW 476
C++ +P+P+L W
Sbjct: 1999 CNATGAPSPTLMW 2011
Score = 66.6 bits (161), Expect = 7e-11
Identities = 54/219 (24%), Positives = 91/219 (41%), Gaps = 27/219 (12%)
Query: 272 LRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG--LELPGVKAGDSGRYTCRAENRL 329
L LLC A PP + W +S G L++ + DSG Y+C A N
Sbjct: 2370 LTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEA 2429
Query: 330 GSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPAR 389
G +R + V PP +EN + VL+GQ+ L+C P +
Sbjct: 2430 GEARRNFSVEVLVPPS-------------IENEDLEEVIKVLDGQTAHLMCNVTGHPQPK 2476
Query: 390 LSWTQRGQVLSPSQ----PSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHYS 445
L+W + G+ L+ D +L++ + + G ++C A + +G + LSV +
Sbjct: 2477 LTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLA 2536
Query: 446 PKLLGPSCSWEAEGLHCS--------CSSQASPAPSLRW 476
P +LG + E + + C + A P+P++ W
Sbjct: 2537 PTILGGAEDSADEEVTVTVNNPISLICEALAFPSPNITW 2575
Score = 66.6 bits (161), Expect = 7e-11
Identities = 80/323 (24%), Positives = 122/323 (37%), Gaps = 48/323 (14%)
Query: 251 PALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLS--SSHPWGPRPLGL 308
P++E + V ++ GQ L+C P L+W R L+ +H P + L
Sbjct: 2444 PSIENEDLEEV--IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLL 2501
Query: 309 ELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSL 368
++ +G Y+C A N +G + + LSV P L A+ V + N S
Sbjct: 2502 QVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPIS- 2560
Query: 369 PVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSD--PGV--LELPRVQVEHEGEFT 424
L+C + P ++W + G S+ PG L++ Q E G++T
Sbjct: 2561 ---------LICEALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYT 2611
Query: 425 CHARHPLGSQHVSLSLSVHYSPKL-----LGPSCSWEAE-----GLHCSCSSQASPAPSL 474
C + LG + + V P + LG E + L C S A P P++
Sbjct: 2612 CVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTLECESWAVPPPTI 2671
Query: 475 RWWLGEELLEGNSSQDSFEVTPSSAGPWANSSLSLH---GGLSSGLRLRCEAWNVHGAQS 531
RW+ +D VTPSS L +S R C A NV G
Sbjct: 2672 RWY-----------KDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDD 2720
Query: 532 ---GSILQLP---DKKGLISTAF 548
++Q+P K G S AF
Sbjct: 2721 QDFNVLIQVPPMFQKVGDFSAAF 2743
Score = 65.9 bits (159), Expect = 1e-10
Identities = 62/223 (27%), Positives = 92/223 (41%), Gaps = 39/223 (17%)
Query: 274 LLCAADSQPPATLSWVLQNRVLSSSHPWGPRPL--------GLELPGVKAGDSGRYTCRA 325
L C A P T+SW LQN + P+ P P L++ + D+ Y C A
Sbjct: 2865 LQCPALGNPVPTISW-LQNGL-----PFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVA 2918
Query: 326 ENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSS 385
EN+ GS ++ L VQ PP + + Q V L + SLP C H+
Sbjct: 2919 ENQAGSAEKLFTLRVQVPPRIAGLDLEQ----VTAILNSSVSLP----------CDVHAH 2964
Query: 386 PPARLSWTQRGQVLSPSQPSD--PGV--LELPRVQVEHEGEFTCHARHPLGSQHVSLSLS 441
P ++W + Q LS + PG L+L R ++ G +TC A + G + LS
Sbjct: 2965 PNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLS 3024
Query: 442 VHYSPKLL----GPSCSW---EAEGLHCSCSSQASPAPSLRWW 477
V P GP + + SC + A P P++ W+
Sbjct: 3025 VLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWY 3067
Score = 65.9 bits (159), Expect = 1e-10
Identities = 84/357 (23%), Positives = 136/357 (38%), Gaps = 52/357 (14%)
Query: 153 TLEPGQPVTVICVFNWAFEECPPPSFSWTGAALSSQGTKPTTSHFSVLSFTPRPQDHNTD 212
+L PG P+ ++C + P P+ +W + + + VL R +D
Sbjct: 3506 SLTPGAPMELLC----DAQGTPQPNITWHKDGQALTRLENNSRATRVL----RVRDAGL- 3556
Query: 213 LTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEPQPQGNVPYLEAQKGQFL 272
TC + + +++ R+RV AP ++V P+G + GQ +
Sbjct: 3557 YTCLAESPAGAI--EKSFRVRVQ-APPNIV-------------GPRGPRFVVGLAPGQLV 3600
Query: 273 RLLCAADSQPPATLSWVLQNRVLSS-SHPWGP-RPLGLELPGVKAGDSGRYTCRAENRLG 330
L C+ +++P ++W VL +H P R L+L + DSG Y+C A N G
Sbjct: 3601 -LECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAG 3659
Query: 331 SQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPARL 390
S A + + P +R N +V Q+ L C P +
Sbjct: 3660 STSVAFRVEIHTVP-TIRSGPPAVNVSV--------------NQTALLPCQADGVPAPLV 3704
Query: 391 SWTQRGQVLSPSQPS----DPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHYSP 446
SW + L P P G L + V + G + C A + GS L V P
Sbjct: 3705 SWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRV-LEP 3763
Query: 447 KLLGPSCSWEAEGLH----CSCSSQASPAPSLRWWLGEELLEGNSSQDSFEVTPSSA 499
+ PS S H C + SP P + WW + L+ Q ++ + PS+A
Sbjct: 3764 PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNA 3820
Score = 65.1 bits (157), Expect = 2e-10
Identities = 83/321 (25%), Positives = 120/321 (37%), Gaps = 54/321 (16%)
Query: 174 PPPSFSWTGAALSSQGTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLR 233
PPP W L +S + + +D T TC SA+ ++L
Sbjct: 725 PPPRVIWYRGGLEMILAPEGSSSGKLRIPAAQERDAGT-YTCRAVNELGDASAE--IQLA 781
Query: 234 VAYAPRDLVISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWV---- 289
V +AP+ + + RD T L G+ L C A +PP T++W
Sbjct: 782 VGHAPQ--LTELPRDVTVEL---------------GRSALLACRATGRPPPTVTWRRGDG 824
Query: 290 ----LQNRVLSSSHPWGPRPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSV--QYP 343
L+ S P L V D Y C A N G Q L V P
Sbjct: 825 QPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAP 884
Query: 344 PENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPA-RLSWTQRGQVLSPS 402
P+ ++ + TV VLEGQ + L C+ + P W + G+ L P
Sbjct: 885 PQ-----IASSAPTVR----------VLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPG 929
Query: 403 QPSD---PGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHYSPKLLGPSCSWEA-- 457
G L L R EH G ++C A + GSQH + L V P+ + P+ +
Sbjct: 930 SRHSIRADGSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQVPPR-IHPTATHHITN 988
Query: 458 EGLHCS--CSSQASPAPSLRW 476
EG+ S C + PAP++ W
Sbjct: 989 EGVPASLPCVASGVPAPTITW 1009
Score = 65.1 bits (157), Expect = 2e-10
Identities = 83/358 (23%), Positives = 130/358 (36%), Gaps = 47/358 (13%)
Query: 136 FLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFEECPP-----PSFSW--TGAALSSQ 188
+L L P V + +T E + VTV + + CP P+ SW G S
Sbjct: 2831 WLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQ-CPALGNPVPTISWLQNGLPFSPS 2889
Query: 189 GTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRD 248
VL + C + + SA++ LRV PR + + +
Sbjct: 2890 PRLQVLEDGQVLQVSTAEVADAASYMCVAE--NQAGSAEKLFTLRVQVPPRIAGLDLEQ- 2946
Query: 249 NTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWG--PRPL 306
+ A + L C + P ++W ++ LS P
Sbjct: 2947 ---------------VTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTH 2991
Query: 307 GLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGT 366
L+L + DSG YTC A N G Q+ + LSV PP QA R G
Sbjct: 2992 TLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPP-----AFRQAPR------GPQD 3040
Query: 367 SLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSDP----GVLELPRVQVEHEGE 422
++ V G L C T + P ++W + GQ L +Q + LE+ QV +G
Sbjct: 3041 AVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGL 3100
Query: 423 FTCHARHPLGSQHVSLSLSVHYSPKLLGPSCSWEAE----GLHCSCSSQASPAPSLRW 476
++C + G + +L+V P P ++ L +C PAP++ W
Sbjct: 3101 YSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTW 3158
Score = 63.9 bits (154), Expect = 5e-10
Identities = 77/290 (26%), Positives = 107/290 (36%), Gaps = 44/290 (15%)
Query: 255 PQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPR----PLG-LE 309
P + P + Q L C AD P +SW L P PR P G L
Sbjct: 3673 PTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLD---PRSPRFEILPEGSLR 3729
Query: 310 LPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLP 369
+ V A D+G Y C A N GS ++ DL V PP + S +N T+ + P
Sbjct: 3730 IQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPP---AIAPSPSNLTLTAH------TP 3780
Query: 370 VLEGQSLCLVCVTHSSPPARLSWTQRGQVLS--------PSQPSDPGVLELPRVQVEHEG 421
L L C SP + W + GQ L PS+ +L P Q
Sbjct: 3781 AL------LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQ--DSA 3832
Query: 422 EFTCHARHPLGSQHVSLSLSVHYSPKLLGPSCSWEAEGLH---CSCSSQASPAPSLRWWL 478
+F C + +G H ++VH P + + + +C S PAP++ W
Sbjct: 3833 QFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSK 3892
Query: 479 GEELLEGNSSQDSFEVTPSSAGPWANSSLSLHGGLSSGLRLRCEAWNVHG 528
L S + V+PS A +L +H G R C A N G
Sbjct: 3893 AGAQLGARGS--GYRVSPSGALE-IGQALPIHAG-----RYTCSARNSAG 3934
Score = 63.2 bits (152), Expect = 8e-10
Identities = 73/290 (25%), Positives = 111/290 (38%), Gaps = 42/290 (14%)
Query: 269 GQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLGLELPGVKAGDSGRYTCRAENR 328
G+ L+C A PP + W + + P G L +P + D+G YTCRA N
Sbjct: 712 GEEAVLVCEASGVPPPRVIWYRGGLEMILA-PEGSSSGKLRIPAAQERDAGTYTCRAVNE 770
Query: 329 LGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPA 388
LG + L+V + P+ +++ R V L G+S L C PP
Sbjct: 771 LGDASAEIQLAVGHAPQ-----LTELPRDVTVEL----------GRSALLACRATGRPPP 815
Query: 389 RLSWTQ-RGQVL---------SPSQPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSL 438
++W + GQ L S S+ D GVL V E + + C AR+ G
Sbjct: 816 TVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEA 875
Query: 439 SLSV--HYSPKLLGPSCS---WEAEGLHCSCSSQASPAPSLRWWLGEELLEGNSSQDSFE 493
L V H P++ + + E + + C A R WL + S+ S
Sbjct: 876 RLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIR 935
Query: 494 VTPSSAGPWANSSLSLHGGLSSGLRLRCEAWNVHGAQSGS---ILQLPDK 540
S + +L H G R C A N G+Q ++Q+P +
Sbjct: 936 ADGSL---HLDRALQEHAG-----RYSCVATNTAGSQHRDVELVVQVPPR 977
Score = 62.0 bits (149), Expect = 2e-09
Identities = 49/184 (26%), Positives = 74/184 (40%), Gaps = 22/184 (11%)
Query: 308 LELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTS 367
L L + G YTC N +G+ + L L V PP+ + T
Sbjct: 2220 LYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQ------------IAGPREPPTQ 2267
Query: 368 LPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPS---QPSDPG-VLELPRVQVEHEGEF 423
+ V++ L C PP ++W + GQ + Q + G L + R Q H G +
Sbjct: 2268 VSVVQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRY 2327
Query: 424 TCHARHPLGSQHVSLSLSVHYSPKLLG---PSCSWEA---EGLHCSCSSQASPAPSLRWW 477
+C A + G LSV P+L+G P + A L C + P P++RW+
Sbjct: 2328 SCVAENLAGRAERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWF 2387
Query: 478 LGEE 481
GEE
Sbjct: 2388 RGEE 2391
Score = 61.6 bits (148), Expect = 2e-09
Identities = 57/212 (26%), Positives = 84/212 (39%), Gaps = 24/212 (11%)
Query: 255 PQPQGNVPYLEAQKGQFLRLLCAA-DSQPPATLSWVLQNRVLSSSHPWGPRPLG-LELPG 312
PQ + P + +GQ + L C +P W+ R L R G L L
Sbjct: 885 PQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDR 944
Query: 313 VKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLE 372
+GRY+C A N GSQ R ++L VQ PP + + T ++ N E
Sbjct: 945 ALQEHAGRYSCVATNTAGSQHRDVELVVQVPP--------RIHPTATHHITN-------E 989
Query: 373 GQSLCLVCVTHSSPPARLSWTQRGQVLSPSQP----SDPGVLELPRVQVEHEGEFTCHAR 428
G L CV P ++WT+ L+ P S G L + + + G + C A
Sbjct: 990 GVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTAT 1049
Query: 429 HPLGSQHVSLSLSVHYSPKLLGPSCSWEAEGL 460
+ +G + LSV+ +L WE GL
Sbjct: 1050 NTVGFSSQEMRLSVN---RLALSKYVWEEYGL 1078
Score = 57.8 bits (138), Expect = 3e-08
Identities = 64/253 (25%), Positives = 99/253 (39%), Gaps = 32/253 (12%)
Query: 248 DNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPR--P 305
D P L P P V G+ L C + P L+WV RVL +S +
Sbjct: 515 DPPPQLVPAPNVTV-----SPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLAD 569
Query: 306 LGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNG 365
L LE+ G+ D GRY C A N G + ++ L V+ P+ + T ++ G
Sbjct: 570 LSLEISGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQ-------VSIHTSSQHFSQG 622
Query: 366 TSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVL---SPSQPSDPGVLELPRVQVEHEGE 422
+ V C P +SW++ Q L S G L + V E G
Sbjct: 623 VEVKV--------SCSASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGN 674
Query: 423 FTCHARHPLGSQHVSLSLSVHYSPKLLGPSC---SWEAEGLHCSCSSQASPAPSLRWWLG 479
++C A + +G+ +++L P + + E C + P P + W+ G
Sbjct: 675 YSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRG 734
Query: 480 --EELL--EGNSS 488
E +L EG+SS
Sbjct: 735 GLEMILAPEGSSS 747
Score = 57.8 bits (138), Expect = 3e-08
Identities = 59/238 (24%), Positives = 90/238 (37%), Gaps = 33/238 (13%)
Query: 269 GQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPR------PLGLELPGVKAGDSGRYT 322
G + L C P + W + + P GP L + G GD GRY
Sbjct: 1423 GADVELQCWTSGVPTPQVEWTKDRQPVL---PGGPHLQVQEDGQVLRITGSHVGDEGRYQ 1479
Query: 323 CRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVT 382
C A + G Q R L V PP + +N T + V+E + L+C
Sbjct: 1480 CVAFSPAGQQARDFQLRVHAPPT-----IWGSNET--------GEVAVMEDHLVQLLCEA 1526
Query: 383 HSSPPARLSWTQRGQVLSPS----QPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSL 438
P ++W + G +L S L+L R Q G +TC A + +G+ +
Sbjct: 1527 RGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKAT 1586
Query: 439 SLSVHYSPKLLG----PSCSWEAEG--LHCSCSSQASPAPSLRW-WLGEELLEGNSSQ 489
L V+ P + G P G + C ++ P+P+L W G + E N S+
Sbjct: 1587 RLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESR 1644
Score = 55.5 bits (132), Expect = 2e-07
Identities = 82/362 (22%), Positives = 129/362 (35%), Gaps = 66/362 (18%)
Query: 140 TALTQKPDVYIPETLEPGQPVTVICVFNWAFEEC-----PPPSFSWTGAALSSQGTKPTT 194
T++ + +++ T+ G P + V A C P P SW + P
Sbjct: 3661 TSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRF 3720
Query: 195 SHFSVLSFTPRP---QDHNTDLTCHVDFSRKGVSAQRTVRL----RVAYAPRDLVISISR 247
S +P QD L C S R +R+ +A +P +L ++
Sbjct: 3721 EILPEGSLRIQPVLAQDAGHYL-CLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTA-- 3777
Query: 248 DNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGP---- 303
+TPAL P C A P + W + L G
Sbjct: 3778 -HTPALLP--------------------CEASGSPKPLVVWWKDGQKLDFRLQQGAYRLL 3816
Query: 304 --RPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLEN 361
L L PG + DS ++ C N +G R ++V PP T+ ++
Sbjct: 3817 PSNALLLTAPGPQ--DSAQFECVVSNEVGEAHRLYQVTVHVPP------------TIADD 3862
Query: 362 LGNGTSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVL----SPSQPSDPGVLELPRVQV 417
T V + L C + P +SW++ G L S + S G LE+ +
Sbjct: 3863 Q---TDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALP 3919
Query: 418 EHEGEFTCHARHPLGSQHVSLSLSVHYSPKLLG-PSC--SWEAEGLHCSCSSQASPAPSL 474
H G +TC AR+ G H + L+V SP + PS + E + C + P P++
Sbjct: 3920 IHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTI 3979
Query: 475 RW 476
W
Sbjct: 3980 TW 3981
Score = 54.7 bits (130), Expect = 3e-07
Identities = 50/189 (26%), Positives = 70/189 (37%), Gaps = 19/189 (10%)
Query: 263 YLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG-LELPGVKAGDSGRY 321
YL G ++L C P + W+ L SH G L + + D+GRY
Sbjct: 4227 YLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRY 4286
Query: 322 TCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCV 381
C AEN +G ++ + L +Q P V Q + V G + L C
Sbjct: 4287 QCLAENEMGVAKKVVILVLQSAP------VFQV---------EPQDMTVRSGDDVALRCQ 4331
Query: 382 THSSPPARLSWTQRGQVLSPS---QPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSL 438
P + W Q GQ L S + G L L V+ G + C A + LGS
Sbjct: 4332 ATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARA 4391
Query: 439 SLSVHYSPK 447
L V P+
Sbjct: 4392 FLVVRGEPQ 4400
Score = 47.0 bits (110), Expect = 6e-05
Identities = 31/105 (29%), Positives = 48/105 (45%), Gaps = 5/105 (4%)
Query: 242 VISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPW 301
V+ + + P + +PQ + + G + L C A +P T+ W+ + L +S
Sbjct: 4300 VVILVLQSAPVFQVEPQD----MTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRL 4355
Query: 302 GPRPLG-LELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPE 345
P G L L V+ GD+G Y C A N LGS L V+ P+
Sbjct: 4356 RTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQ 4400
Score = 43.1 bits (100), Expect = 9e-04
Identities = 46/187 (24%), Positives = 75/187 (40%), Gaps = 24/187 (12%)
Query: 309 ELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSL 368
E+ + G Y C A +R G+ + + V PP L V N T
Sbjct: 482 EILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQL---VPAPNVT----------- 527
Query: 369 PVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPS-----QPSDPGVLELPRVQVEHEGEF 423
V G++ L C P L+W + +VL S Q +D LE+ + G +
Sbjct: 528 -VSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLADLS-LEISGIIPTDGGRY 585
Query: 424 TCHARHPLGSQHVSLSLSVHYSPKL-LGPSCSWEAEGLH--CSCSSQASPAPSLRWWLGE 480
C A + G S+ L V +P++ + S ++G+ SCS+ P P + W
Sbjct: 586 QCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRES 645
Query: 481 ELLEGNS 487
+ L+ +S
Sbjct: 646 QALQEDS 652
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 90.1 bits (222), Expect = 6e-18
Identities = 91/329 (27%), Positives = 135/329 (41%), Gaps = 48/329 (14%)
Query: 156 PGQPVTVICVFNWAFEECPPPSFSWTGAALSSQGTKPTTSHFSVLSFT-PRPQDHNTDLT 214
PG+ VT++C + PP SW L ++ T H S + + Q + +
Sbjct: 2045 PGELVTMVCPVRGS----PPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIF 2100
Query: 215 CHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEP-QPQGNVPYLEAQKGQFLR 273
V S GV A R L+V P LEP + Q +V + +G +
Sbjct: 2101 TCVAASPAGV-ADRNFTLQVQVPP-------------VLEPVEFQNDVVVV---RGSLVE 2143
Query: 274 LLCAADSQPPATLSWVLQNR-VLSSSHPWGPRPLGLELPGVKAGDSGRYTCRAENRLGSQ 332
L C A P +SW+ +LS S GP L+L V AGDSG Y+C A + G
Sbjct: 2144 LPCEARGVPLPLVSWMKDGEPLLSQSLEQGP---SLQLEAVGAGDSGTYSCVAVSEAGEA 2200
Query: 333 QRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPARLSW 392
+R L+V PP +E+ G T L + G + L+C +P ++W
Sbjct: 2201 RRHFQLTVMEPPH-------------IEDSGQPTELSLTPGAPMELLCDAQGTPQPNITW 2247
Query: 393 TQRGQVLSPSQPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHYSPKLLGPS 452
+ GQ L+ + + L +V G +TC A P G+ S + V P ++GP
Sbjct: 2248 HKDGQALTRLENNSRATRVL---RVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPR 2304
Query: 453 CSWEAEGLH-----CSCSSQASPAPSLRW 476
GL CS +A PAP + W
Sbjct: 2305 GPRFVVGLAPGQLVLECSVEAEPAPKITW 2333
Score = 84.3 bits (207), Expect = 3e-16
Identities = 100/420 (23%), Positives = 157/420 (37%), Gaps = 76/420 (18%)
Query: 98 KGNCSLVIRDAQMQDESQYFFRVERGSYVRYNFMNDGFFLKVTALTQKPDVYIPETLE-- 155
+G L I++AQ+ D+ Y +V + G ++ LT V +P T E
Sbjct: 1801 RGGQRLEIQEAQVSDKGLYSCKVSNVA---------GEAVRTFTLT----VQVPPTFENP 1847
Query: 156 --------PGQPVTVICVFNWAFEECPPPSFSWTGAAL--SSQGTKPTTSHFSVLSFTPR 205
G P+ + C + P P+ +W + S S L +
Sbjct: 1848 KTETVSQVAGSPLVLTCDVSGV----PAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRL 1903
Query: 206 PQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEPQPQGNVPYLE 265
TC + ++ A++ + V APR ++R++
Sbjct: 1904 QPAQAGTYTCVAENTQ--AEARKDFVVAVLVAPRIRSSGVAREH---------------H 1946
Query: 266 AQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPL------GLELPGVKAGDSG 319
+GQ +RL C AD QPP ++W+ L GP L L G++A D+G
Sbjct: 1947 VLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQD--MGPHLRFYLDGGSLVLKGLRASDAG 2004
Query: 320 RYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLV 379
YTC A N G R ++V PP T+ + +L G+ + +V
Sbjct: 2005 AYTCVAHNPAGEDARLHTVNVLVPP------------TIKQGADGSGTLVSRPGELVTMV 2052
Query: 380 CVTHSSPPARLSWTQRGQVLSPSQPS----DPGVLELPRVQVEHEGEFTCHARHPLGSQH 435
C SPP +SW + G L SQ + L + +VQ+ G FTC A P G
Sbjct: 2053 CPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGVAD 2112
Query: 436 VSLSLSVHYSPKLLGPSCSWEAEGLHCS-----CSSQASPAPSLRWWL-GEELLEGNSSQ 489
+ +L V P L + + S C ++ P P + W GE LL + Q
Sbjct: 2113 RNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQ 2172
Score = 84.0 bits (206), Expect = 4e-16
Identities = 97/365 (26%), Positives = 144/365 (39%), Gaps = 62/365 (16%)
Query: 148 VYIPETLEPGQPVTVICVFNWAFE-EC-----PPPSFSWTGAALSSQGTKPTTSHFSV-L 200
V +P +EPG PV + N + EC PPP SW +G +P +S V +
Sbjct: 600 VLVPPNIEPG-PVNKAVLENASVTLECLASGVPPPDVSWF------KGHQPVSSWMGVTV 652
Query: 201 SFTPR----PQDHNTDLTCH-VDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEP 255
S R Q +D + S S + LRV PR + P+L
Sbjct: 653 SVDGRVLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITL-------PPSLPG 705
Query: 256 QPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWG----PRPLGLELP 311
N P +RL C A P TL W+ +S + G P L L
Sbjct: 706 PVLVNTP---------VRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLA 756
Query: 312 GVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVL 371
+A DSGRY+C A + +G ++ + L V PP L G ++ V+
Sbjct: 757 SARASDSGRYSCVAVSAVGEDRQDVVLQVHMPPSIL---------------GEELNVSVV 801
Query: 372 EGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQ----PSDPGVLELPRVQVEHEGEFTCHA 427
+S+ L C +H+ PP LSW + G+ L P +D +L++ R V G +TC A
Sbjct: 802 ANESVALECQSHAMPPPVLSWWKDGRPLEPRPGVHLSADKALLQVDRADVWDAGHYTCEA 861
Query: 428 RHPLGSQHVSLSLSVHYSPKL-LGPSCSW---EAEGLHCSCSSQASPAPSLRWWLGEELL 483
+ G +L+V +P L S + E SC + P P + W + L
Sbjct: 862 LNQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGHPTRLSCECRGVPFPKISWRKDGQPL 921
Query: 484 EGNSS 488
G +
Sbjct: 922 PGEGA 926
Score = 83.2 bits (204), Expect = 8e-16
Identities = 74/265 (27%), Positives = 106/265 (40%), Gaps = 43/265 (16%)
Query: 249 NTPALEP---QPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPW---- 301
NT ++ P + G + GQ L L C A+ P + W+ +++ W
Sbjct: 10 NTGSVVPPSIREDGRKANVSGMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYG 69
Query: 302 ---------GPRPL----GLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLR 348
G R L L P ++ GDSG Y+CRAEN+ G+ QR L V PP L
Sbjct: 70 WDLGWGQVGGHRLLDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVLG 129
Query: 349 VMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQP---- 404
+Q E LG L G + L C T P ++ WT+ Q + P P
Sbjct: 130 AGAAQ------EVLG-------LAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQV 176
Query: 405 -SDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHYSPKLLGPSCSWEAEGL--- 460
D VL + V EG + C A P G Q L VH P + G + + E +
Sbjct: 177 QEDGQVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRVHAPPTIWGSNETGEVAVMEDH 236
Query: 461 --HCSCSSQASPAPSLRWWLGEELL 483
C ++ P P++ W+ LL
Sbjct: 237 LVQLLCEARGVPTPNITWFKDGALL 261
Score = 81.6 bits (200), Expect = 2e-15
Identities = 74/292 (25%), Positives = 118/292 (40%), Gaps = 47/292 (16%)
Query: 272 LRLLCAADSQPPATLSWVLQNRVLSSS----HPWGPRPLGLELPGVKAGDSGRYTCRAEN 327
++LLC A P ++W +L +S + G R L +L ++ D+G YTC+A N
Sbjct: 238 VQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGGRQL--QLGRAQSSDAGVYTCKASN 295
Query: 328 RLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPP 387
+G+ ++A L V PP T+ G + + G+ + L CV P
Sbjct: 296 AVGAAEKATRLDVYVPP------------TIEGAGGRPYVVKAVAGRPVALECVARGHPS 343
Query: 388 ARLSWTQRGQVLSPSQPS----DPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVH 443
LSW G ++ S S D VL L G ++C A P G + S+ V
Sbjct: 344 PTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQ 403
Query: 444 YSPKL-----LGPSCSWEAEGLHCSCSSQASPAPSLRWWLGEELLEGNSSQDSFEVTPSS 498
P+L LG + + L C + SP P+++W L G +++ V +S
Sbjct: 404 VPPQLLVAEGLGQVTTIVGQPLELPCQASGSPVPTIQW-----LQNGRPAEELAGVQVAS 458
Query: 499 AGPWANSSLSLHGGLSSGLRLRCEAWN------------VHGAQSGSILQLP 538
G + H L C+A N VHG + +L++P
Sbjct: 459 QGTTLHID---HVELDHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVP 507
Score = 79.7 bits (195), Expect = 8e-15
Identities = 74/278 (26%), Positives = 116/278 (41%), Gaps = 31/278 (11%)
Query: 254 EPQPQGNVP-YLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG--LEL 310
E + +G V Y E + L C ++ PP L+W +++ LS+ G L++
Sbjct: 1467 EEEARGGVTEYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQI 1526
Query: 311 PGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPV 370
P V+A ++GRY+C+A N +G +L V PP V++ V E N +S
Sbjct: 1527 PLVRAENAGRYSCKASNEVGEDWLHYELLVLTPP----VILGDTEELVEEVTVNASS--- 1579
Query: 371 LEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQP----SDPGVLELPRVQVEHEGEFTCH 426
++ L C +P +SW Q G SPS D VL++ +V + C
Sbjct: 1580 ----TVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYMCV 1635
Query: 427 ARHPLGSQHVSLSLSVHYSPKLLGPSCSWEAEGLHCS----CSSQASPAPSLRWW----- 477
A + GS +L V P++ G L+ S C A P P + W+
Sbjct: 1636 AENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQA 1695
Query: 478 --LGEE--LLEGNSSQDSFEVTPSSAGPWANSSLSLHG 511
LGEE LL G + S +G + +L+ G
Sbjct: 1696 LSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAG 1733
Score = 75.5 bits (184), Expect = 2e-13
Identities = 83/347 (23%), Positives = 143/347 (41%), Gaps = 42/347 (12%)
Query: 153 TLEPGQPVTVICVFNWAFEECPPPSFSWTGAALSSQGTK-----PTTSHFSVLSFTPRPQ 207
T+ P+++IC AF P P+ +W + ++ P T +L+ +
Sbjct: 1270 TVTVNNPISLICEA-LAF---PSPNITWMKDGAPFEASRNIQLLPGTHGLQILN---AQK 1322
Query: 208 DHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEPQPQGNVPYLEAQ 267
+ TC V + + A + + V P SIS+D +P + V ++ +
Sbjct: 1323 EDAGQYTCVV--TNELGEAVKNYHVEVLIPP-----SISKD-----DPLAEVGVKEVKTK 1370
Query: 268 KGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG--LELPGVKAGDSGRYTCRA 325
L L C + + PP T+ W + ++ S G L++ + DSGRY C A
Sbjct: 1371 VNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVA 1430
Query: 326 ENRLGSQQRALDLSVQYPPENLRVMVSQANRTVL----ENLGNGTSL-PVLEGQSLCLVC 380
N G + ++ +Q PP +V A +L E G T ++E L C
Sbjct: 1431 TNVAGEDDQDFNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYC 1490
Query: 381 VTHSSPPARLSWTQRGQVLSP----SQPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHV 436
T++ PP L+W + Q LS S VL++P V+ E+ G ++C A + +G +
Sbjct: 1491 DTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWL 1550
Query: 437 SLSLSVHYSPKLLGPSCSWEAE-------GLHCSCSSQASPAPSLRW 476
L V P +LG + E + C + +P P++ W
Sbjct: 1551 HYELLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISW 1597
Score = 73.6 bits (179), Expect = 6e-13
Identities = 85/361 (23%), Positives = 140/361 (38%), Gaps = 54/361 (14%)
Query: 148 VYIPETLEPGQPVTVICVFNWAFEEC-----PPPSFSWT--GAALSSQGTKPTTSHFSVL 200
V++P T+ Q + + C P P+ SW+ GA L ++G+ S L
Sbjct: 2571 VHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGAL 2630
Query: 201 SFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEPQPQGN 260
H TC + R A + + +++ +P ++P P
Sbjct: 2631 EIGQALPIHAGRYTC-------------SARNSAGVAHKHVFLTVQA--SPVVKPLPS-- 2673
Query: 261 VPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG-LELPGVKAGDSG 319
+ A + + L C A P T++W + +++ P G L + D+G
Sbjct: 2674 --VVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAG 2731
Query: 320 RYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLV 379
Y C A+N GS L VQ PP V+EN L EG L
Sbjct: 2732 NYLCIAKNSAGSAMGKTRLVVQVPP-------------VIEN--GLPDLSTTEGSHAFLP 2776
Query: 380 CVTHSSPPARLSWTQRGQVLSPS------QPSDPGVLELPRVQVEHEGEFTCHARHPLGS 433
C SP ++W + GQ +S + QPS G L + ++ + G +TC A + +G
Sbjct: 2777 CKARGSPEPNITWDKDGQPVSGAEGKFTIQPS--GELLVKNLEGQDAGTYTCTAENAVGR 2834
Query: 434 QHVSLSLSVHYSP---KLLGPSCSWEAEGLHCSCSSQASPAPSLRWWLGEE-LLEGNSSQ 489
+ L++ P L G + L C+++ SP P + W + + + EG S Q
Sbjct: 2835 ARRRVHLTILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQ 2894
Query: 490 D 490
D
Sbjct: 2895 D 2895
Score = 71.6 bits (174), Expect = 2e-12
Identities = 62/224 (27%), Positives = 90/224 (40%), Gaps = 42/224 (18%)
Query: 274 LLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLGLELPGVKA---------GDSGRYTCR 324
L C + + PP LSW R P PRP G+ L KA D+G YTC
Sbjct: 808 LECQSHAMPPPVLSWWKDGR------PLEPRP-GVHLSADKALLQVDRADVWDAGHYTCE 860
Query: 325 AENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHS 384
A N+ G ++ +L+V P + L +L V EG L C
Sbjct: 861 ALNQAGHSEKHYNLNVWVAP--------------VFPLRESHTLTVREGHPTRLSCECRG 906
Query: 385 SPPARLSWTQRGQVLSPSQPSDPGV------LELPRVQVEHEGEFTCHARHPLGSQHVSL 438
P ++SW + GQ L V L L + Q+ EG +TC + +G+ L
Sbjct: 907 VPFPKISWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDL 966
Query: 439 SLSVHYSPKLLGP-----SCSWEAEGL-HCSCSSQASPAPSLRW 476
L VH P++ GP S +G+ C++ P P++ W
Sbjct: 967 QLEVHVPPQIAGPREPPTQVSVVQDGVATLECNATGKPPPTVTW 1010
Score = 69.7 bits (169), Expect = 9e-12
Identities = 65/277 (23%), Positives = 109/277 (39%), Gaps = 47/277 (16%)
Query: 274 LLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLGLELPG---------VKAGDSGRYTCR 324
L C A +PP T++W + + + LGL+L +A +GRY+C
Sbjct: 996 LECNATGKPPPTVTWERDGQPVGAE-------LGLQLQNQGQSLHVERAQAAHTGRYSCV 1048
Query: 325 AENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHS 384
AEN G +R +LSV PPE ++ +L T++ L L+C
Sbjct: 1049 AENLAGRAERKFELSVLVPPE------------LIGDLDPLTNITAALHSPLTLLCEAMG 1096
Query: 385 SPPARLSWTQRGQVLSPSQP----SDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSL 440
PP + W + + +SP + + +L++ + Q + G ++C A + G + S+
Sbjct: 1097 IPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSV 1156
Query: 441 SVHYSPKLLGPSCS-----WEAEGLHCSCSSQASPAPSLRWWL-GEELLEGNSSQDSFEV 494
V P + + + H C+ P P L W+ G L G D+ +
Sbjct: 1157 EVLVPPSIENEDLEEVIKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARG----DAHHI 1212
Query: 495 TPSSAGPWANSSLSLHGGLSSGLRLRCEAWNVHGAQS 531
+P L LSS C A N G ++
Sbjct: 1213 SPDGV-----LLQVLQANLSSAGHYSCIAANAVGEKT 1244
Score = 69.3 bits (168), Expect = 1e-11
Identities = 68/231 (29%), Positives = 98/231 (42%), Gaps = 27/231 (11%)
Query: 259 GNVPYL-EAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSH----PWGPRPLGLELPGV 313
G PY+ +A G+ + L C A P TLSW + ++ S+ L LE PG
Sbjct: 318 GGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPG- 376
Query: 314 KAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEG 373
SG Y+C A + G + VQ PP+ L V E LG T+ + G
Sbjct: 377 -EASSGLYSCVASSPAGEAVLQYSVEVQVPPQLL----------VAEGLGQVTT---IVG 422
Query: 374 QSLCLVCVTHSSPPARLSWTQRG---QVLSPSQPSDPG-VLELPRVQVEHEGEFTCHARH 429
Q L L C SP + W Q G + L+ Q + G L + V+++H G F C A +
Sbjct: 423 QPLELPCQASGSPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATN 482
Query: 430 PLGSQHVSLSLSVH--YSPKLLG-PSCSWEAEGLHCSCSSQASPAPSLRWW 477
G+ + +SVH ++P +L P + H S A P R W
Sbjct: 483 EAGTAGAEVEVSVHGEWAPGVLEVPIGQYHWGXEHHSSFPAACDPPVHRGW 533
Score = 69.3 bits (168), Expect = 1e-11
Identities = 57/230 (24%), Positives = 91/230 (39%), Gaps = 23/230 (10%)
Query: 255 PQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSH-PWGPRPLG-LELPG 312
P + +P L +G L C A P ++W + +S + + +P G L +
Sbjct: 2756 PVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKN 2815
Query: 313 VKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLE 372
++ D+G YTC AEN +G +R + L++ P V L SL +
Sbjct: 2816 LEGQDAGTYTCTAENAVGRARRRVHLTILVLP-------------VFTTLPGDRSLRL-- 2860
Query: 373 GQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSDPGVLELPRVQVEHE--GEFTCHARHP 430
G L L C SP R+ WT + ++ G L R V E G + C A +
Sbjct: 2861 GDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENR 2920
Query: 431 LGSQHVSLSLSVHYSPKLLGPSCSWEAE----GLHCSCSSQASPAPSLRW 476
+G + V +P L G + S+ E + C + P P + W
Sbjct: 2921 VGRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGSIQLDCVVRGDPVPDIHW 2970
Score = 68.9 bits (167), Expect = 1e-11
Identities = 101/433 (23%), Positives = 159/433 (36%), Gaps = 79/433 (18%)
Query: 69 KGAPVATNHQSREVEMSTRGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFRVERGSYVRY 128
+G PVA +++SR + R + G+ + G S V + QY V+ V
Sbjct: 351 EGLPVAESNESRLETDGSVLRLESPGEASSGLYSCVASSPAGEAVLQYSVEVQ----VPP 406
Query: 129 NFMNDGFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFEECPPPSFSWTGAALSSQ 188
+ +VT + +P + +P G PV I W + P+ G ++SQ
Sbjct: 407 QLLVAEGLGQVTTIVGQP-LELP-CQASGSPVPTI---QWL--QNGRPAEELAGVQVASQ 459
Query: 189 GTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISR- 247
GT H + DH+ C A+ V + +AP L + I +
Sbjct: 460 GTTLHIDHVEL--------DHSGLFACQATNEAGTAGAEVEVSVHGEWAPGVLEVPIGQY 511
Query: 248 -------DNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHP 300
+ PA P +G A +PP W S
Sbjct: 512 HWGXEHHSSFPAACDPP--------VHRG------WGAHPKPPLVEGW------CSPGSL 551
Query: 301 WG---------PRPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMV 351
WG P L++ V D G YTC A N G +R + L V PP +
Sbjct: 552 WGEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCAATNLAGESKREVALKVLVPP---NIEP 608
Query: 352 SQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSP----SQPSDP 407
N+ VLEN S+ L C+ PP +SW + Q +S + D
Sbjct: 609 GPVNKAVLEN------------ASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDG 656
Query: 408 GVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHYSPKL-LGPSCSWEA---EGLHCS 463
VL + + Q+ G + C A + GS + L V+ P++ L PS + +
Sbjct: 657 RVLRIEQAQLSDAGSYRCVASNVAGSTELRYGLRVNVPPRITLPPSLPGPVLVNTPVRLT 716
Query: 464 CSSQASPAPSLRW 476
C++ +P+P+L W
Sbjct: 717 CNATGAPSPTLMW 729
Score = 65.9 bits (159), Expect = 1e-10
Identities = 78/323 (24%), Positives = 119/323 (36%), Gaps = 48/323 (14%)
Query: 251 PALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLS--SSHPWGPRPLGL 308
P++E + V ++ GQ L+C P L+W R L+ +H P + L
Sbjct: 1162 PSIENEDLEEV--IKVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHHISPDGVLL 1219
Query: 309 ELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSL 368
++ +G Y+C A N +G + + LSV P L A+ V + N S
Sbjct: 1220 QVLQANLSSAGHYSCIAANAVGEKTKHFQLSVLLAPTILGGAEDSADEEVTVTVNNPIS- 1278
Query: 369 PVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSD--PGV--LELPRVQVEHEGEFT 424
L+C + P ++W + G S+ PG L++ Q E G++T
Sbjct: 1279 ---------LICEALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKEDAGQYT 1329
Query: 425 CHARHPLGSQHVSLSLSVHYSPKLLGPSCSWEA----------EGLHCSCSSQASPAPSL 474
C + LG + + V P + E L C S A P P++
Sbjct: 1330 CVVTNELGEAVKNYHVEVLIPPSISKDDPLAEVGVKEVKTKVNSTLTLECESWAVPPPTI 1389
Query: 475 RWWLGEELLEGNSSQDSFEVTPSSAGPWANSSLSLH---GGLSSGLRLRCEAWNVHGAQS 531
RW+ +D VTPSS L +S R C A NV G
Sbjct: 1390 RWY-----------KDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDD 1438
Query: 532 ---GSILQLP---DKKGLISTAF 548
++Q+P K G S AF
Sbjct: 1439 QDFNVLIQVPPMFQKVGDFSAAF 1461
Score = 65.9 bits (159), Expect = 1e-10
Identities = 62/223 (27%), Positives = 92/223 (41%), Gaps = 39/223 (17%)
Query: 274 LLCAADSQPPATLSWVLQNRVLSSSHPWGPRPL--------GLELPGVKAGDSGRYTCRA 325
L C A P T+SW LQN + P+ P P L++ + D+ Y C A
Sbjct: 1583 LQCPALGNPVPTISW-LQNGL-----PFSPSPRLQVLEDGQVLQVSTAEVADAASYMCVA 1636
Query: 326 ENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSS 385
EN+ GS ++ L VQ PP + + Q V L + SLP C H+
Sbjct: 1637 ENQAGSAEKLFTLRVQVPPRIAGLDLEQ----VTAILNSSVSLP----------CDVHAH 1682
Query: 386 PPARLSWTQRGQVLSPSQPSD--PGV--LELPRVQVEHEGEFTCHARHPLGSQHVSLSLS 441
P ++W + Q LS + PG L+L R ++ G +TC A + G + LS
Sbjct: 1683 PNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLS 1742
Query: 442 VHYSPKLL----GPSCSW---EAEGLHCSCSSQASPAPSLRWW 477
V P GP + + SC + A P P++ W+
Sbjct: 1743 VLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWY 1785
Score = 65.9 bits (159), Expect = 1e-10
Identities = 84/357 (23%), Positives = 136/357 (38%), Gaps = 52/357 (14%)
Query: 153 TLEPGQPVTVICVFNWAFEECPPPSFSWTGAALSSQGTKPTTSHFSVLSFTPRPQDHNTD 212
+L PG P+ ++C + P P+ +W + + + VL R +D
Sbjct: 2224 SLTPGAPMELLC----DAQGTPQPNITWHKDGQALTRLENNSRATRVL----RVRDAGL- 2274
Query: 213 LTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEPQPQGNVPYLEAQKGQFL 272
TC + + +++ R+RV AP ++V P+G + GQ +
Sbjct: 2275 YTCLAESPAGAI--EKSFRVRVQ-APPNIV-------------GPRGPRFVVGLAPGQLV 2318
Query: 273 RLLCAADSQPPATLSWVLQNRVLSS-SHPWGP-RPLGLELPGVKAGDSGRYTCRAENRLG 330
L C+ +++P ++W VL +H P R L+L + DSG Y+C A N G
Sbjct: 2319 -LECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALSTADSGDYSCTARNAAG 2377
Query: 331 SQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPARL 390
S A + + P +R N +V Q+ L C P +
Sbjct: 2378 STSVAFRVEIHTVP-TIRSGPPAVNVSV--------------NQTALLPCQADGVPAPLV 2422
Query: 391 SWTQRGQVLSPSQPS----DPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHYSP 446
SW + L P P G L + V + G + C A + GS L V P
Sbjct: 2423 SWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRV-LEP 2481
Query: 447 KLLGPSCSWEAEGLH----CSCSSQASPAPSLRWWLGEELLEGNSSQDSFEVTPSSA 499
+ PS S H C + SP P + WW + L+ Q ++ + PS+A
Sbjct: 2482 PAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNA 2538
Score = 65.1 bits (157), Expect = 2e-10
Identities = 83/358 (23%), Positives = 130/358 (36%), Gaps = 47/358 (13%)
Query: 136 FLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFEECPP-----PSFSW--TGAALSSQ 188
+L L P V + +T E + VTV + + CP P+ SW G S
Sbjct: 1549 WLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQ-CPALGNPVPTISWLQNGLPFSPS 1607
Query: 189 GTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRD 248
VL + C + + SA++ LRV PR + + +
Sbjct: 1608 PRLQVLEDGQVLQVSTAEVADAASYMCVAE--NQAGSAEKLFTLRVQVPPRIAGLDLEQ- 1664
Query: 249 NTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWG--PRPL 306
+ A + L C + P ++W ++ LS P
Sbjct: 1665 ---------------VTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTH 1709
Query: 307 GLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGT 366
L+L + DSG YTC A N G Q+ + LSV PP QA R G
Sbjct: 1710 TLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPP-----AFRQAPR------GPQD 1758
Query: 367 SLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSDP----GVLELPRVQVEHEGE 422
++ V G L C T + P ++W + GQ L +Q + LE+ QV +G
Sbjct: 1759 AVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVSDKGL 1818
Query: 423 FTCHARHPLGSQHVSLSLSVHYSPKLLGPSCSWEAE----GLHCSCSSQASPAPSLRW 476
++C + G + +L+V P P ++ L +C PAP++ W
Sbjct: 1819 YSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTW 1876
Score = 63.9 bits (154), Expect = 5e-10
Identities = 60/233 (25%), Positives = 89/233 (38%), Gaps = 28/233 (12%)
Query: 264 LEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSS-----HPWGPRPLGLELPGVKAGDS 318
L ++G RL C P +SW + L H L L L +
Sbjct: 890 LTVREGHPTRLSCECRGVPFPKISWRKDGQPLPGEGAGLQHVSAVGRL-LYLGQAQLAQE 948
Query: 319 GRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCL 378
G YTC N +G+ + L L V PP+ + T + V++ L
Sbjct: 949 GTYTCECSNVVGNSSQDLQLEVHVPPQ------------IAGPREPPTQVSVVQDGVATL 996
Query: 379 VCVTHSSPPARLSWTQRGQVLSPS---QPSDPG-VLELPRVQVEHEGEFTCHARHPLGSQ 434
C PP ++W + GQ + Q + G L + R Q H G ++C A + G
Sbjct: 997 ECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRA 1056
Query: 435 HVSLSLSVHYSPKLLG---PSCSWEA---EGLHCSCSSQASPAPSLRWWLGEE 481
LSV P+L+G P + A L C + P P++RW+ GEE
Sbjct: 1057 ERKFELSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEE 1109
Score = 63.9 bits (154), Expect = 5e-10
Identities = 77/290 (26%), Positives = 107/290 (36%), Gaps = 44/290 (15%)
Query: 255 PQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPR----PLG-LE 309
P + P + Q L C AD P +SW L P PR P G L
Sbjct: 2391 PTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLD---PRSPRFEILPEGSLR 2447
Query: 310 LPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLP 369
+ V A D+G Y C A N GS ++ DL V PP + S +N T+ + P
Sbjct: 2448 IQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPP---AIAPSPSNLTLTAH------TP 2498
Query: 370 VLEGQSLCLVCVTHSSPPARLSWTQRGQVLS--------PSQPSDPGVLELPRVQVEHEG 421
L L C SP + W + GQ L PS+ +L P Q
Sbjct: 2499 AL------LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQ--DSA 2550
Query: 422 EFTCHARHPLGSQHVSLSLSVHYSPKLLGPSCSWEAEGLH---CSCSSQASPAPSLRWWL 478
+F C + +G H ++VH P + + + +C S PAP++ W
Sbjct: 2551 QFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSK 2610
Query: 479 GEELLEGNSSQDSFEVTPSSAGPWANSSLSLHGGLSSGLRLRCEAWNVHG 528
L S + V+PS A +L +H G R C A N G
Sbjct: 2611 AGAQLGARGS--GYRVSPSGALE-IGQALPIHAG-----RYTCSARNSAG 2652
Score = 57.8 bits (138), Expect = 3e-08
Identities = 59/238 (24%), Positives = 90/238 (37%), Gaps = 33/238 (13%)
Query: 269 GQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPR------PLGLELPGVKAGDSGRYT 322
G + L C P + W + + P GP L + G GD GRY
Sbjct: 141 GADVELQCWTSGVPTPQVEWTKDRQPVL---PGGPHLQVQEDGQVLRITGSHVGDEGRYQ 197
Query: 323 CRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVT 382
C A + G Q R L V PP + +N T + V+E + L+C
Sbjct: 198 CVAFSPAGQQARDFQLRVHAPPT-----IWGSNET--------GEVAVMEDHLVQLLCEA 244
Query: 383 HSSPPARLSWTQRGQVLSPS----QPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSL 438
P ++W + G +L S L+L R Q G +TC A + +G+ +
Sbjct: 245 RGVPTPNITWFKDGALLPTSTKVVYTRGGRQLQLGRAQSSDAGVYTCKASNAVGAAEKAT 304
Query: 439 SLSVHYSPKLLG----PSCSWEAEG--LHCSCSSQASPAPSLRW-WLGEELLEGNSSQ 489
L V+ P + G P G + C ++ P+P+L W G + E N S+
Sbjct: 305 RLDVYVPPTIEGAGGRPYVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESR 362
Score = 55.5 bits (132), Expect = 2e-07
Identities = 82/362 (22%), Positives = 129/362 (35%), Gaps = 66/362 (18%)
Query: 140 TALTQKPDVYIPETLEPGQPVTVICVFNWAFEEC-----PPPSFSWTGAALSSQGTKPTT 194
T++ + +++ T+ G P + V A C P P SW + P
Sbjct: 2379 TSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRF 2438
Query: 195 SHFSVLSFTPRP---QDHNTDLTCHVDFSRKGVSAQRTVRL----RVAYAPRDLVISISR 247
S +P QD L C S R +R+ +A +P +L ++
Sbjct: 2439 EILPEGSLRIQPVLAQDAGHYL-CLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTA-- 2495
Query: 248 DNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGP---- 303
+TPAL P C A P + W + L G
Sbjct: 2496 -HTPALLP--------------------CEASGSPKPLVVWWKDGQKLDFRLQQGAYRLL 2534
Query: 304 --RPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLEN 361
L L PG + DS ++ C N +G R ++V PP T+ ++
Sbjct: 2535 PSNALLLTAPGPQ--DSAQFECVVSNEVGEAHRLYQVTVHVPP------------TIADD 2580
Query: 362 LGNGTSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVL----SPSQPSDPGVLELPRVQV 417
T V + L C + P +SW++ G L S + S G LE+ +
Sbjct: 2581 Q---TDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALP 2637
Query: 418 EHEGEFTCHARHPLGSQHVSLSLSVHYSPKLLG-PSC--SWEAEGLHCSCSSQASPAPSL 474
H G +TC AR+ G H + L+V SP + PS + E + C + P P++
Sbjct: 2638 IHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTI 2697
Query: 475 RW 476
W
Sbjct: 2698 TW 2699
Score = 54.7 bits (130), Expect = 3e-07
Identities = 50/189 (26%), Positives = 70/189 (37%), Gaps = 19/189 (10%)
Query: 263 YLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG-LELPGVKAGDSGRY 321
YL G ++L C P + W+ L SH G L + + D+GRY
Sbjct: 2945 YLVEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGSLTIRRTERDDAGRY 3004
Query: 322 TCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCV 381
C AEN +G ++ + L +Q P V Q + V G + L C
Sbjct: 3005 QCLAENEMGVAKKVVILVLQSAP------VFQV---------EPQDMTVRSGDDVALRCQ 3049
Query: 382 THSSPPARLSWTQRGQVLSPS---QPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSL 438
P + W Q GQ L S + G L L V+ G + C A + LGS
Sbjct: 3050 ATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARA 3109
Query: 439 SLSVHYSPK 447
L V P+
Sbjct: 3110 FLVVRGEPQ 3118
Score = 47.0 bits (110), Expect = 6e-05
Identities = 31/105 (29%), Positives = 48/105 (45%), Gaps = 5/105 (4%)
Query: 242 VISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPW 301
V+ + + P + +PQ + + G + L C A +P T+ W+ + L +S
Sbjct: 3018 VVILVLQSAPVFQVEPQD----MTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRL 3073
Query: 302 GPRPLG-LELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPE 345
P G L L V+ GD+G Y C A N LGS L V+ P+
Sbjct: 3074 RTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARAFLVVRGEPQ 3118
>gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo
sapiens]
Length = 848
Score = 83.2 bits (204), Expect = 8e-16
Identities = 70/277 (25%), Positives = 109/277 (39%), Gaps = 43/277 (15%)
Query: 256 QPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHP-----WGPRPLGLEL 310
Q + N+ A GQ + L+C A+ P T+SW + + L +
Sbjct: 215 QARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTI 274
Query: 311 PGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPV 370
V D Y C AEN+ G Q + L V P+ V N+T +E
Sbjct: 275 KKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYV----ENQTAME---------- 320
Query: 371 LEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSDPG-----------VLELPRVQVEH 419
LE Q + L C P ++W + +S + + G L L +Q
Sbjct: 321 LEEQ-VTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTD 379
Query: 420 EGEFTCHARHPLGSQHVSLSLSVHYSPKLLGPSC--SWEAEGLHCSCSSQASPAPSLRWW 477
GE+ C A + +G S+ L V Y+PKL GP +WE ++ +C A P+ ++ W+
Sbjct: 380 AGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWF 439
Query: 478 LGEELLEGNS----------SQDSFEVTPSSAGPWAN 504
+LL ++ S EVTP S + N
Sbjct: 440 RDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGN 476
Score = 63.9 bits (154), Expect = 5e-10
Identities = 58/245 (23%), Positives = 94/245 (38%), Gaps = 50/245 (20%)
Query: 255 PQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNR-----------VLSSSHPWGP 303
P PQ E ++G+ ++C S P T+ W + R VLS+++
Sbjct: 124 PTPQ------EFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNY---- 173
Query: 304 RPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLS--VQYPPENLRVMVSQANRTVLEN 361
L++ G+K D G Y C + D+ V PP QA + ++
Sbjct: 174 ----LQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPP------TIQARQNIVNA 223
Query: 362 LGNGTSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQ-------PSDPGVLELPR 414
N GQS+ LVC P +SWT+ G+ + + D L + +
Sbjct: 224 TAN-------LGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKK 276
Query: 415 VQVEHEGEFTCHARHPLGSQHVSLSLSVHYSPKLL---GPSCSWEAEGLHCSCSSQASPA 471
V E E+ C A + G Q ++ L V PK+ + E + +C + P
Sbjct: 277 VDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPI 336
Query: 472 PSLRW 476
PS+ W
Sbjct: 337 PSITW 341
Score = 39.3 bits (90), Expect = 0.012
Identities = 58/244 (23%), Positives = 94/244 (38%), Gaps = 41/244 (16%)
Query: 103 LVIRDAQMQDESQYFFRVERGSYVRYNFMNDGFFLKVTALTQKPDVYIPETLEPGQPVTV 162
L I+ DE++Y E + + LKV A + V +E + VT+
Sbjct: 272 LTIKKVDKNDEAEYICIAEN----KAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTL 327
Query: 163 ICVFNWAFEECPPPSFSWTGAA--LSSQ-----GTKPTTSHFSVLSFTPRPQDHNTDLTC 215
C + P PS +W + +SS+ G SH V S T + + TD
Sbjct: 328 TCEASGD----PIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQY-TDAGE 382
Query: 216 HVDFSRKGVSAQ-RTVRLRVAYAPRDLVISISRDNTPALEPQPQGNVPYLEAQKGQFLRL 274
++ + + +++ L V YAP+ QG V + +G + +
Sbjct: 383 YICTASNTIGQDSQSMYLEVQYAPK-----------------LQGPVA-VYTWEGNQVNI 424
Query: 275 LCAADSQPPATLSWVLQNRVLSSSHPWG------PRPLGLELPGVKAGDSGRYTCRAENR 328
C + P AT+SW ++L SS+ P LE+ D G Y C A NR
Sbjct: 425 TCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNR 484
Query: 329 LGSQ 332
+G +
Sbjct: 485 IGQE 488
>gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo
sapiens]
Length = 761
Score = 83.2 bits (204), Expect = 8e-16
Identities = 70/277 (25%), Positives = 109/277 (39%), Gaps = 43/277 (15%)
Query: 256 QPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHP-----WGPRPLGLEL 310
Q + N+ A GQ + L+C A+ P T+SW + + L +
Sbjct: 215 QARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTI 274
Query: 311 PGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPV 370
V D Y C AEN+ G Q + L V P+ V N+T +E
Sbjct: 275 KKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYV----ENQTAME---------- 320
Query: 371 LEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSDPG-----------VLELPRVQVEH 419
LE Q + L C P ++W + +S + + G L L +Q
Sbjct: 321 LEEQ-VTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTD 379
Query: 420 EGEFTCHARHPLGSQHVSLSLSVHYSPKLLGPSC--SWEAEGLHCSCSSQASPAPSLRWW 477
GE+ C A + +G S+ L V Y+PKL GP +WE ++ +C A P+ ++ W+
Sbjct: 380 AGEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWF 439
Query: 478 LGEELLEGNS----------SQDSFEVTPSSAGPWAN 504
+LL ++ S EVTP S + N
Sbjct: 440 RDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGN 476
Score = 63.9 bits (154), Expect = 5e-10
Identities = 58/245 (23%), Positives = 94/245 (38%), Gaps = 50/245 (20%)
Query: 255 PQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNR-----------VLSSSHPWGP 303
P PQ E ++G+ ++C S P T+ W + R VLS+++
Sbjct: 124 PTPQ------EFREGEDAVIVCDVVSSLPPTIIWKHKGRDVILKKDVRFIVLSNNY---- 173
Query: 304 RPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLS--VQYPPENLRVMVSQANRTVLEN 361
L++ G+K D G Y C + D+ V PP QA + ++
Sbjct: 174 ----LQIRGIKKTDEGTYRCEGRILARGEINFKDIQVIVNVPP------TIQARQNIVNA 223
Query: 362 LGNGTSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQ-------PSDPGVLELPR 414
N GQS+ LVC P +SWT+ G+ + + D L + +
Sbjct: 224 TAN-------LGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDSSQLTIKK 276
Query: 415 VQVEHEGEFTCHARHPLGSQHVSLSLSVHYSPKLL---GPSCSWEAEGLHCSCSSQASPA 471
V E E+ C A + G Q ++ L V PK+ + E + +C + P
Sbjct: 277 VDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGDPI 336
Query: 472 PSLRW 476
PS+ W
Sbjct: 337 PSITW 341
Score = 39.3 bits (90), Expect = 0.012
Identities = 58/244 (23%), Positives = 94/244 (38%), Gaps = 41/244 (16%)
Query: 103 LVIRDAQMQDESQYFFRVERGSYVRYNFMNDGFFLKVTALTQKPDVYIPETLEPGQPVTV 162
L I+ DE++Y E + + LKV A + V +E + VT+
Sbjct: 272 LTIKKVDKNDEAEYICIAEN----KAGEQDATIHLKVFAKPKITYVENQTAMELEEQVTL 327
Query: 163 ICVFNWAFEECPPPSFSWTGAA--LSSQ-----GTKPTTSHFSVLSFTPRPQDHNTDLTC 215
C + P PS +W + +SS+ G SH V S T + + TD
Sbjct: 328 TCEASGD----PIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLKSIQY-TDAGE 382
Query: 216 HVDFSRKGVSAQ-RTVRLRVAYAPRDLVISISRDNTPALEPQPQGNVPYLEAQKGQFLRL 274
++ + + +++ L V YAP+ QG V + +G + +
Sbjct: 383 YICTASNTIGQDSQSMYLEVQYAPK-----------------LQGPVA-VYTWEGNQVNI 424
Query: 275 LCAADSQPPATLSWVLQNRVLSSSHPWG------PRPLGLELPGVKAGDSGRYTCRAENR 328
C + P AT+SW ++L SS+ P LE+ D G Y C A NR
Sbjct: 425 TCEVFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNR 484
Query: 329 LGSQ 332
+G +
Sbjct: 485 IGQE 488
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 82.4 bits (202), Expect = 1e-15
Identities = 81/303 (26%), Positives = 126/303 (41%), Gaps = 54/303 (17%)
Query: 251 PALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPL---- 306
P QPQ E G+ + L C+A PP +SW +R + P PR
Sbjct: 342 PTFVIQPQNT----EVLVGESVTLECSATGHPPPRISWTRGDR---TPLPVDPRVNITPS 394
Query: 307 -GLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNG 365
GL + V GDSG Y C A N + S + VQ P+ V+ +R V+E
Sbjct: 395 GGLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQALPQ---FTVTPQDRVVIE----- 446
Query: 366 TSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPSQPS---DPGVLELPRVQVEHEGE 422
GQ++ C +PP ++WT+ G LS + G L + V + +G+
Sbjct: 447 -------GQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSGTLRISGVALHDQGQ 499
Query: 423 FTCHARHPLGSQHVSLSLSVHYSPKLLGPSCSWEAE-------GLHCSCSSQASPAPSLR 475
+ C A + +GSQ V L+V P++ S ++ + CSSQ P P++
Sbjct: 500 YECQAVNIIGSQKVVAHLTVQ--PRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAIT 557
Query: 476 WWLGEELLEGNSSQDSFEVTPSS---AGPWANSSLSLHGGLSSGLRLRCEAWNVHGAQSG 532
W ++D +VT S P +++ G +G R C A N G+ S
Sbjct: 558 W-----------NKDGVQVTESGKFHISPEGFLTINDVGPADAG-RYECVARNTIGSASV 605
Query: 533 SIL 535
S++
Sbjct: 606 SMV 608
Score = 68.6 bits (166), Expect = 2e-11
Identities = 105/432 (24%), Positives = 161/432 (37%), Gaps = 69/432 (15%)
Query: 28 SVMVPEGLCISVPCSFSYPRQ-DWTGSTPAYGYWFKAVTETTKGAPVATNHQSREVEMST 86
+ + PE L P S P+ D T Y F E + + E+ M T
Sbjct: 234 ATITPEELNCERPRITSEPQDADVTSGNTVY---FTCRAEGNPKPEIIWLRNNNELSMKT 290
Query: 87 RGRFQLTGDPAKGNCSLVIRDAQMQDESQYFFRVERGSYVRYNFMNDGFFLKVTALTQKP 146
R L D +L+I++ Q D+ Y + V L+ +P
Sbjct: 291 DSRLNLLDDG-----TLMIQNTQETDQGIYQCMAKN---VAGEVKTQEVTLRYFGSPARP 342
Query: 147 DVYI-PETLEP--GQPVTVICVFNWAFEECPPPSFSWTGAALSSQGTKPTTSHFSVLSFT 203
I P+ E G+ VT+ C + PPP SWT +G + T
Sbjct: 343 TFVIQPQNTEVLVGESVTLEC----SATGHPPPRISWT------RGDR-----------T 381
Query: 204 PRPQDHNTDLT----CHVDFSRKGVSAQ----RTVRLRVAYAPRDLVISISRDNTPALEP 255
P P D ++T ++ +G S + T + +A +++ P
Sbjct: 382 PLPVDPRVNITPSGGLYIQNVVQGDSGEYACSATNNIDSVHATAFIIVQA----LPQFTV 437
Query: 256 QPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG-LELPGVK 314
PQ V +GQ + C A PP ++W LS G L + GV
Sbjct: 438 TPQDRVVI----EGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSGTLRISGVA 493
Query: 315 AGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQ 374
D G+Y C+A N +GSQ+ L+VQ P V S + T +E +G LP
Sbjct: 494 LHDQGQYECQAVNIIGSQKVVAHLTVQ--PRVTPVFASIPSDTTVE-VGANVQLP----- 545
Query: 375 SLCLVCVTHSSPPARLSWTQRGQVLSPS---QPSDPGVLELPRVQVEHEGEFTCHARHPL 431
C + P ++W + G ++ S S G L + V G + C AR+ +
Sbjct: 546 -----CSSQGEPEPAITWNKDGVQVTESGKFHISPEGFLTINDVGPADAGRYECVARNTI 600
Query: 432 GSQHVSLSLSVH 443
GS VS+ LSV+
Sbjct: 601 GSASVSMVLSVN 612
Score = 39.7 bits (91), Expect = 0.010
Identities = 23/76 (30%), Positives = 38/76 (50%), Gaps = 1/76 (1%)
Query: 269 GQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG-LELPGVKAGDSGRYTCRAEN 327
G ++L C++ +P ++W ++ S + P G L + V D+GRY C A N
Sbjct: 539 GANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEGFLTINDVGPADAGRYECVARN 598
Query: 328 RLGSQQRALDLSVQYP 343
+GS ++ LSV P
Sbjct: 599 TIGSASVSMVLSVNVP 614
>gi|33519481 neural cell adhesion molecule 2 precursor [Homo
sapiens]
Length = 837
Score = 82.4 bits (202), Expect = 1e-15
Identities = 76/349 (21%), Positives = 139/349 (39%), Gaps = 52/349 (14%)
Query: 147 DVYIPETLEPGQPVTVICVFNWAFEECPPPSFSWTGAALSSQGTKPTTSHFSVLSFTPRP 206
+V P+ + G+ V+C P P+ SW + + T + + F++L+
Sbjct: 119 EVVSPQEFKQGEDAEVVC----RVSSSPAPAVSWLYH--NEEVTTISDNRFAMLA----- 167
Query: 207 QDHNTDLTCHVDFSRKGV-SAQRTVRLRVAYAPRDLVISISRDNTPALEPQPQGNVPYLE 265
+N +++ S +G+ + V R RD+++ + N P PQ +
Sbjct: 168 --NNNLQILNINKSDEGIYRCEGRVEARGEIDFRDIIVIV---NVPPAISMPQKSFN-AT 221
Query: 266 AQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLGLELP--GVKAGDSGRYTC 323
A++G+ + C A P +SW +++ + + + EL + D G Y C
Sbjct: 222 AERGEEMTFSCRASGSPEPAISWFRNGKLIEENEKYILKGSNTELTVRNIINSDGGPYVC 281
Query: 324 RAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTH 383
RA N+ G ++ L V P ++ N T EN GQ + LVC
Sbjct: 282 RATNKAGEDEKQAFLQVFVQPH----IIQLKNETTYEN-----------GQ-VTLVCDAE 325
Query: 384 SSPPARLSWTQR--GQVLSPSQPSDPGVLE-----------LPRVQVEHEGEFTCHARHP 430
P ++W + G + S G +E + V++ G + C A
Sbjct: 326 GEPIPEITWKRAVDGFTFTEGDKSLDGRIEVKGQHGSSSLHIKDVKLSDSGRYDCEAASR 385
Query: 431 LGSQHVSLSLSVHYSPKLLGPSC---SWEAEGLHCSCSSQASPAPSLRW 476
+G S+ L + Y+PK + SWE ++ SC +++P S+ W
Sbjct: 386 IGGHQKSMYLDIEYAPKFISNQTIYYSWEGNPINISCDVKSNPPASIHW 434
Score = 55.1 bits (131), Expect = 2e-07
Identities = 44/189 (23%), Positives = 82/189 (43%), Gaps = 39/189 (20%)
Query: 267 QKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPL-------------GLELPGV 313
+ GQ + L+C A+ +P ++W + V + G + L L + V
Sbjct: 314 ENGQ-VTLVCDAEGEPIPEITW--KRAVDGFTFTEGDKSLDGRIEVKGQHGSSSLHIKDV 370
Query: 314 KAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEG 373
K DSGRY C A +R+G Q+++ L ++Y P+ + +N+T+ + EG
Sbjct: 371 KLSDSGRYDCEAASRIGGHQKSMYLDIEYAPKFI------SNQTIYYS---------WEG 415
Query: 374 QSLCLVCVTHSSPPARLSWTQRGQVLSPSQPSD--------PGVLELPRVQVEHEGEFTC 425
+ + C S+PPA + W + VL ++ +LE+ G + C
Sbjct: 416 NPINISCDVKSNPPASIHWRRDKLVLPAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNC 475
Query: 426 HARHPLGSQ 434
A + +G++
Sbjct: 476 TATNHIGTR 484
Score = 43.5 bits (101), Expect = 7e-04
Identities = 41/182 (22%), Positives = 71/182 (39%), Gaps = 26/182 (14%)
Query: 317 DSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSL 376
D+G Y C+A + G Q A + Y R +VS +G+
Sbjct: 87 DAGIYRCQATDAKGQTQEATVVLEIYQKLTFREVVSPQE--------------FKQGEDA 132
Query: 377 CLVCVTHSSPPARLSWTQRGQVLSPSQPSDPGVLELPRVQV-----EHEGEFTCHARHPL 431
+VC SSP +SW + ++ + +L +Q+ EG + C R
Sbjct: 133 EVVCRVSSSPAPAVSWLYHNEEVTTISDNRFAMLANNNLQILNINKSDEGIYRCEGRVEA 192
Query: 432 GSQ--HVSLSLSVHYSPKLLGPSCSWEA-----EGLHCSCSSQASPAPSLRWWLGEELLE 484
+ + + V+ P + P S+ A E + SC + SP P++ W+ +L+E
Sbjct: 193 RGEIDFRDIIVIVNVPPAISMPQKSFNATAERGEEMTFSCRASGSPEPAISWFRNGKLIE 252
Query: 485 GN 486
N
Sbjct: 253 EN 254
Score = 37.4 bits (85), Expect = 0.047
Identities = 48/210 (22%), Positives = 77/210 (36%), Gaps = 39/210 (18%)
Query: 153 TLEPGQPVTVICVFNWAFEECPPPSFSWTGAA---LSSQGTKPTTSHFSVLSFTPRPQDH 209
T E GQ VT++C E P P +W A ++G K V H
Sbjct: 312 TYENGQ-VTLVC----DAEGEPIPEITWKRAVDGFTFTEGDKSLDGRIEVKGQHGSSSLH 366
Query: 210 NTDLTCHVDFSRKGVSA-------QRTVRLRVAYAPRDLVISISRDNTPALEPQPQGNVP 262
D+ D R A Q+++ L + YAP+ + N
Sbjct: 367 IKDVKLS-DSGRYDCEAASRIGGHQKSMYLDIEYAPKFI-----------------SNQT 408
Query: 263 YLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWG------PRPLGLELPGVKAG 316
+ +G + + C S PPA++ W VL + + R + LE+
Sbjct: 409 IYYSWEGNPINISCDVKSNPPASIHWRRDKLVLPAKNTTNLKTYSTGRKMILEIAPTSDN 468
Query: 317 DSGRYTCRAENRLGSQQRALDLSVQYPPEN 346
D GRY C A N +G++ + L++ P +
Sbjct: 469 DFGRYNCTATNHIGTRFQEYILALADVPSS 498
>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
Length = 1215
Score = 81.3 bits (199), Expect = 3e-15
Identities = 73/273 (26%), Positives = 115/273 (42%), Gaps = 37/273 (13%)
Query: 268 KGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLG-LELPGVKAGDSGRYTCRAE 326
+G +++ C+A P +SW +++ L G L + GV D+G Y+C+A
Sbjct: 504 QGVEVKVSCSASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQAT 563
Query: 327 NRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSP 386
N +G+ Q + L PP VS N VL V G+ LVC P
Sbjct: 564 NEVGTDQETVTLYYTDPPS-----VSAVNAVVL----------VAVGEEAVLVCEASGVP 608
Query: 387 PARLSWTQRG--QVLSPSQPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHY 444
P R+ W + G +L+P + S G L +P Q G +TC A + LG + L+V +
Sbjct: 609 PPRVIWYRGGLEMILAP-EGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGH 667
Query: 445 SPKL--LGPSCSWE-AEGLHCSCSSQASPAPSLRWW------LGEELLEGNSSQDS---- 491
+P+L L + E +C + P P++ W LG L G S+
Sbjct: 668 APQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDS 727
Query: 492 ----FE-VTPSSAGPWANSSLSLHGGLSSGLRL 519
FE V P P+ + ++ G + + RL
Sbjct: 728 GVLFFESVAPEDQAPYVCEARNVFGKVQAEARL 760
Score = 65.5 bits (158), Expect = 2e-10
Identities = 60/238 (25%), Positives = 94/238 (39%), Gaps = 31/238 (13%)
Query: 255 PQPQGNVPYLEAQKGQFLRLLCAA-DSQPPATLSWVLQNRVLSSSHPWGPRPLG-LELPG 312
PQ + P + +GQ + L C +P W+ R L R G L L
Sbjct: 768 PQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRADGSLHLDR 827
Query: 313 VKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLE 372
+GRY+C A N GSQ R ++L VQ PP + + T ++ N E
Sbjct: 828 ALQEHAGRYSCVATNTAGSQHRDVELVVQVPP--------RIHPTATHHITN-------E 872
Query: 373 GQSLCLVCVTHSSPPARLSWTQRGQVLSPSQP----SDPGVLELPRVQVEHEGEFTCHAR 428
G L CV P ++WT+ L+ P S G L + + + G + C A
Sbjct: 873 GVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTAT 932
Query: 429 HPLGSQHVSLSLSVHYSPKL-LGPS---------CSWEAEGLHCSCSSQASPAPSLRW 476
+ +G + LSV+ P++ + S + E + C ++ SP P + W
Sbjct: 933 NTVGFSSQEMRLSVNTKPRIHMNGSRNANVPLQVTAKAGEEVTLDCEAKGSPPPLVTW 990
Score = 65.1 bits (157), Expect = 2e-10
Identities = 83/321 (25%), Positives = 120/321 (37%), Gaps = 54/321 (16%)
Query: 174 PPPSFSWTGAALSSQGTKPTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLR 233
PPP W L +S + + +D T TC SA+ ++L
Sbjct: 608 PPPRVIWYRGGLEMILAPEGSSSGKLRIPAAQERDAGT-YTCRAVNELGDASAE--IQLA 664
Query: 234 VAYAPRDLVISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWV---- 289
V +AP+ + + RD T L G+ L C A +PP T++W
Sbjct: 665 VGHAPQ--LTELPRDVTVEL---------------GRSALLACRATGRPPPTVTWRRGDG 707
Query: 290 ----LQNRVLSSSHPWGPRPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSV--QYP 343
L+ S P L V D Y C A N G Q L V P
Sbjct: 708 QPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHAP 767
Query: 344 PENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPA-RLSWTQRGQVLSPS 402
P+ ++ + TV VLEGQ + L C+ + P W + G+ L P
Sbjct: 768 PQ-----IASSAPTVR----------VLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPG 812
Query: 403 QPSD---PGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHYSPKLLGPSCSWEA-- 457
G L L R EH G ++C A + GSQH + L V P+ + P+ +
Sbjct: 813 SRHSIRADGSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQVPPR-IHPTATHHITN 871
Query: 458 EGLHCS--CSSQASPAPSLRW 476
EG+ S C + PAP++ W
Sbjct: 872 EGVPASLPCVASGVPAPTITW 892
Score = 63.2 bits (152), Expect = 8e-10
Identities = 73/290 (25%), Positives = 111/290 (38%), Gaps = 42/290 (14%)
Query: 269 GQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLGLELPGVKAGDSGRYTCRAENR 328
G+ L+C A PP + W + + P G L +P + D+G YTCRA N
Sbjct: 595 GEEAVLVCEASGVPPPRVIWYRGGLEMILA-PEGSSSGKLRIPAAQERDAGTYTCRAVNE 653
Query: 329 LGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPA 388
LG + L+V + P+ +++ R V L G+S L C PP
Sbjct: 654 LGDASAEIQLAVGHAPQ-----LTELPRDVTVEL----------GRSALLACRATGRPPP 698
Query: 389 RLSWTQ-RGQVL---------SPSQPSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSL 438
++W + GQ L S S+ D GVL V E + + C AR+ G
Sbjct: 699 TVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEA 758
Query: 439 SLSV--HYSPKLLGPSCS---WEAEGLHCSCSSQASPAPSLRWWLGEELLEGNSSQDSFE 493
L V H P++ + + E + + C A R WL + S+ S
Sbjct: 759 RLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIR 818
Query: 494 VTPSSAGPWANSSLSLHGGLSSGLRLRCEAWNVHGAQSGS---ILQLPDK 540
S + +L H G R C A N G+Q ++Q+P +
Sbjct: 819 ADGSL---HLDRALQEHAG-----RYSCVATNTAGSQHRDVELVVQVPPR 860
Score = 60.5 bits (145), Expect = 5e-09
Identities = 57/208 (27%), Positives = 85/208 (40%), Gaps = 29/208 (13%)
Query: 274 LLCAADSQPPATLSWVLQNRVLSSSHP-WGPRPLG-LELPGVKAGDSGRYTCRAENRLGS 331
L C A P T++W + L+S P + G L + A D+G Y C A N +G
Sbjct: 878 LPCVASGVPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGF 937
Query: 332 QQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTHSSPPARLS 391
+ + LSV P R+ ++ + N + G+ + L C SPP ++
Sbjct: 938 SSQEMRLSVNTKP---RIHMNGSR-----NANVPLQVTAKAGEEVTLDCEAKGSPPPLVT 989
Query: 392 WTQRGQVLSPSQ------PSDPGVLELPRVQVEHEGEFTCHARHPLGSQHVSLSLSVHYS 445
WT+ + + P PS G L L +VQV G + C A +P GS L V
Sbjct: 990 WTKDSRPVPPITNRYGLLPS--GSLRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQ-- 1045
Query: 446 PKLLGPSCSWEAEGL----HCSCSSQAS 469
SW+ + L H +C S S
Sbjct: 1046 -----GRTSWQPQSLPVPHHPACLSGLS 1068
Score = 57.8 bits (138), Expect = 3e-08
Identities = 64/253 (25%), Positives = 99/253 (39%), Gaps = 32/253 (12%)
Query: 248 DNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPR--P 305
D P L P P V G+ L C + P L+WV RVL +S +
Sbjct: 398 DPPPQLVPAPNVTV-----SPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLAD 452
Query: 306 LGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNG 365
L LE+ G+ D GRY C A N G + ++ L V+ P+ + T ++ G
Sbjct: 453 LSLEISGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQ-------VSIHTSSQHFSQG 505
Query: 366 TSLPVLEGQSLCLVCVTHSSPPARLSWTQRGQVL---SPSQPSDPGVLELPRVQVEHEGE 422
+ V C P +SW++ Q L S G L + V E G
Sbjct: 506 VEVKV--------SCSASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGN 557
Query: 423 FTCHARHPLGSQHVSLSLSVHYSPKLLGPSC---SWEAEGLHCSCSSQASPAPSLRWWLG 479
++C A + +G+ +++L P + + E C + P P + W+ G
Sbjct: 558 YSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRG 617
Query: 480 --EELL--EGNSS 488
E +L EG+SS
Sbjct: 618 GLEMILAPEGSSS 630
Score = 55.1 bits (131), Expect = 2e-07
Identities = 55/203 (27%), Positives = 86/203 (42%), Gaps = 28/203 (13%)
Query: 157 GQPVTVICVFNWAFEECPPPSFSWTGA--ALSSQGTKPTTSHFSVLSFT-PRPQDHNTDL 213
G P ++ CV + P P+ +WT AL+S+G S L P QD +
Sbjct: 873 GVPASLPCVASGV----PAPTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQDAGAYV 928
Query: 214 TCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEPQPQGNVPY-LEAQKGQFL 272
T V ++ +++ +S++ + NVP + A+ G+ +
Sbjct: 929 C--------------TATNTVGFSSQEMRLSVNTKPRIHMNGSRNANVPLQVTAKAGEEV 974
Query: 273 RLLCAADSQPPATLSWVLQNR-VLSSSHPWGPRPLG-LELPGVKAGDSGRYTCRAENRLG 330
L C A PP ++W +R V ++ +G P G L L V+ GDSG Y C A N G
Sbjct: 975 TLDCEAKGSPPPLVTWTKDSRPVPPITNRYGLLPSGSLRLAQVQVGDSGHYECTASNPAG 1034
Query: 331 SQQRALDLSVQ----YPPENLRV 349
S L VQ + P++L V
Sbjct: 1035 SASHRYVLGVQGRTSWQPQSLPV 1057
Score = 43.1 bits (100), Expect = 9e-04
Identities = 46/187 (24%), Positives = 75/187 (40%), Gaps = 24/187 (12%)
Query: 309 ELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSL 368
E+ + G Y C A +R G+ + + V PP L V N T
Sbjct: 365 EILRASKAEEGTYECTAVSRAGTGRAKAQIVVTDPPPQL---VPAPNVT----------- 410
Query: 369 PVLEGQSLCLVCVTHSSPPARLSWTQRGQVLSPS-----QPSDPGVLELPRVQVEHEGEF 423
V G++ L C P L+W + +VL S Q +D LE+ + G +
Sbjct: 411 -VSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLADLS-LEISGIIPTDGGRY 468
Query: 424 TCHARHPLGSQHVSLSLSVHYSPKL-LGPSCSWEAEGLH--CSCSSQASPAPSLRWWLGE 480
C A + G S+ L V +P++ + S ++G+ SCS+ P P + W
Sbjct: 469 QCVASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRES 528
Query: 481 ELLEGNS 487
+ L+ +S
Sbjct: 529 QALQEDS 535
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,163,995
Number of Sequences: 37866
Number of extensions: 1748892
Number of successful extensions: 11915
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 159
Number of HSP's successfully gapped in prelim test: 336
Number of HSP's that attempted gapping in prelim test: 8493
Number of HSP's gapped (non-prelim): 2252
length of query: 697
length of database: 18,247,518
effective HSP length: 109
effective length of query: 588
effective length of database: 14,120,124
effective search space: 8302632912
effective search space used: 8302632912
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.