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Search of human proteins with 31324577
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31324577 molecule interacting with Rab13 [Homo sapiens]
(863 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31324577 molecule interacting with Rab13 [Homo sapiens] 1757 0.0
gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens] 419 e-117
gi|205360947 microtubule associated monoxygenase, calponin and L... 138 2e-32
gi|226530313 microtubule associated monoxygenase, calponin and L... 138 2e-32
gi|170172518 microtubule associated monoxygenase, calponin and L... 123 6e-28
gi|209862793 microtubule associated monoxygenase, calponin and L... 123 6e-28
gi|209862789 microtubule associated monoxygenase, calponin and L... 123 6e-28
gi|7662284 microtubule associated monoxygenase, calponin and LIM... 117 4e-26
gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens] 113 9e-25
gi|4501893 actinin, alpha 2 [Homo sapiens] 112 1e-24
gi|4557241 actinin, alpha 3 [Homo sapiens] 112 2e-24
gi|150378549 tangerin [Homo sapiens] 110 4e-24
gi|194097352 actinin, alpha 1 isoform c [Homo sapiens] 110 6e-24
gi|194097350 actinin, alpha 1 isoform a [Homo sapiens] 110 6e-24
gi|4501891 actinin, alpha 1 isoform b [Homo sapiens] 110 6e-24
gi|170016061 spectrin, beta, non-erythrocytic 5 [Homo sapiens] 109 1e-23
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 108 2e-23
gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo ... 108 2e-23
gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo ... 108 2e-23
gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1 [... 107 4e-23
gi|12025678 actinin, alpha 4 [Homo sapiens] 106 8e-23
gi|217330574 EH domain binding protein 1 isoform 3 [Homo sapiens] 104 3e-22
gi|217330572 EH domain binding protein 1 isoform 3 [Homo sapiens] 104 3e-22
gi|217330570 EH domain binding protein 1 isoform 2 [Homo sapiens] 104 3e-22
gi|217330568 EH domain binding protein 1 isoform 1 [Homo sapiens] 104 3e-22
gi|67782321 spectrin beta isoform a [Homo sapiens] 103 5e-22
gi|67782319 spectrin beta isoform b [Homo sapiens] 103 5e-22
gi|163965366 nascent polypeptide-associated complex alpha subuni... 100 6e-21
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 100 8e-21
gi|118918413 MICAL C-terminal like [Homo sapiens] 98 4e-20
>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
Length = 863
Score = 1757 bits (4550), Expect = 0.0
Identities = 863/863 (100%), Positives = 863/863 (100%)
Query: 1 MAGPRGALLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVF 60
MAGPRGALLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVF
Sbjct: 1 MAGPRGALLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVF 60
Query: 61 ENNRLAFEVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHFCSPGQAGVSPPRK 120
ENNRLAFEVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHFCSPGQAGVSPPRK
Sbjct: 61 ENNRLAFEVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHFCSPGQAGVSPPRK 120
Query: 121 GLAPCSPPSVAPTPVEPEDVAQGEELSSGSLSEQGTGQTPSSTCAACQQHVHLVQRYLAD 180
GLAPCSPPSVAPTPVEPEDVAQGEELSSGSLSEQGTGQTPSSTCAACQQHVHLVQRYLAD
Sbjct: 121 GLAPCSPPSVAPTPVEPEDVAQGEELSSGSLSEQGTGQTPSSTCAACQQHVHLVQRYLAD 180
Query: 181 GRLYHRHCFRCRRCSSTLLPGAYENGPEEGTFVCAEHCARLGPGTRSGTRPGPFSQPKQQ 240
GRLYHRHCFRCRRCSSTLLPGAYENGPEEGTFVCAEHCARLGPGTRSGTRPGPFSQPKQQ
Sbjct: 181 GRLYHRHCFRCRRCSSTLLPGAYENGPEEGTFVCAEHCARLGPGTRSGTRPGPFSQPKQQ 240
Query: 241 HQQQLAEDAKDVPGGGPSSSAPAGAEADGPKASPEARPQIPTKPRVPGKLQELASPPAGR 300
HQQQLAEDAKDVPGGGPSSSAPAGAEADGPKASPEARPQIPTKPRVPGKLQELASPPAGR
Sbjct: 241 HQQQLAEDAKDVPGGGPSSSAPAGAEADGPKASPEARPQIPTKPRVPGKLQELASPPAGR 300
Query: 301 PTPAPRKASESTTPAPPTPRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKPRGTPKPSE 360
PTPAPRKASESTTPAPPTPRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKPRGTPKPSE
Sbjct: 301 PTPAPRKASESTTPAPPTPRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKPRGTPKPSE 360
Query: 361 GTPAPRKDPPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQPSPTASLE 420
GTPAPRKDPPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQPSPTASLE
Sbjct: 361 GTPAPRKDPPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQPSPTASLE 420
Query: 421 SKPYNPFEEEEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPTSSPKTKKRPAP 480
SKPYNPFEEEEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPTSSPKTKKRPAP
Sbjct: 421 SKPYNPFEEEEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPTSSPKTKKRPAP 480
Query: 481 RAPSASPLALHASRLSHSEPPSATPSPALSVESLSSESASQTAGAELLEPPAVPKSSSEP 540
RAPSASPLALHASRLSHSEPPSATPSPALSVESLSSESASQTAGAELLEPPAVPKSSSEP
Sbjct: 481 RAPSASPLALHASRLSHSEPPSATPSPALSVESLSSESASQTAGAELLEPPAVPKSSSEP 540
Query: 541 AVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAPRTRGSSGPQPAKPCSGA 600
AVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAPRTRGSSGPQPAKPCSGA
Sbjct: 541 AVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAPRTRGSSGPQPAKPCSGA 600
Query: 601 TPTPLLLVGDRSPVPSPGSSSPQLQVKSSCKENPFNRKPSPAASPATKKATKGSKPVRPP 660
TPTPLLLVGDRSPVPSPGSSSPQLQVKSSCKENPFNRKPSPAASPATKKATKGSKPVRPP
Sbjct: 601 TPTPLLLVGDRSPVPSPGSSSPQLQVKSSCKENPFNRKPSPAASPATKKATKGSKPVRPP 660
Query: 661 APGHGFPLIKRKVQADQYIPEEDIHGEMDTIERRLDALEHRGVLLEEKLRGGLNEGREDD 720
APGHGFPLIKRKVQADQYIPEEDIHGEMDTIERRLDALEHRGVLLEEKLRGGLNEGREDD
Sbjct: 661 APGHGFPLIKRKVQADQYIPEEDIHGEMDTIERRLDALEHRGVLLEEKLRGGLNEGREDD 720
Query: 721 MLVDWFKLIHEKHLLVRRESELIYVFKQQNLEQRQADVEYELRCLLNKPEKDWTEEDRAR 780
MLVDWFKLIHEKHLLVRRESELIYVFKQQNLEQRQADVEYELRCLLNKPEKDWTEEDRAR
Sbjct: 721 MLVDWFKLIHEKHLLVRRESELIYVFKQQNLEQRQADVEYELRCLLNKPEKDWTEEDRAR 780
Query: 781 EKVLMQELVTLIEQRNAIINCLDEDRQREEEEDKMLEAMIKKKEFQREAEPEGKKKGKFK 840
EKVLMQELVTLIEQRNAIINCLDEDRQREEEEDKMLEAMIKKKEFQREAEPEGKKKGKFK
Sbjct: 781 EKVLMQELVTLIEQRNAIINCLDEDRQREEEEDKMLEAMIKKKEFQREAEPEGKKKGKFK 840
Query: 841 TMKMLKLLGNKRDAKSKSPRDKS 863
TMKMLKLLGNKRDAKSKSPRDKS
Sbjct: 841 TMKMLKLLGNKRDAKSKSPRDKS 863
>gi|33667117 MICAL-like 2 isoform 1 [Homo sapiens]
Length = 904
Score = 419 bits (1077), Expect = e-117
Identities = 332/928 (35%), Positives = 443/928 (47%), Gaps = 130/928 (14%)
Query: 7 ALLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFENNRLA 66
AL WCR+QCEGYR V I ++++SFRDGLAFCAILHRHRPDL++F +L K+N++ENN+LA
Sbjct: 6 ALQQWCRQQCEGYRDVNICNMTTSFRDGLAFCAILHRHRPDLINFSALKKENIYENNKLA 65
Query: 67 FEVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHF--CSP--GQAGV------- 115
F VAE+ LGIPALLD DMV++ VPD LSI+TYVSQYYN+F SP G AGV
Sbjct: 66 FRVAEEHLGIPALLDAEDMVALKVPDRLSILTYVSQYYNYFHGRSPIGGMAGVKRASEDS 125
Query: 116 --------SPPRKGLAPCSPPSVAP--TPVEPEDVAQGEELSSG----SLSEQGTGQTPS 161
+P + P P+ P +P + V Q +G + G S
Sbjct: 126 EEEPSGKKAPVQAAKLPSPAPARKPPLSPAQTNPVVQRRNEGAGGPPPKTDQALAGSLVS 185
Query: 162 STCAACQQHVHLVQRYLADGRLYHRHCFRCRRCSSTLLPGAYENGPEEGTFVCAEH---C 218
STC C +HVHLVQR+LADGRLYHR CFRC++CS TL GAY+ E GTFVC H
Sbjct: 186 STCGVCGKHVHLVQRHLADGRLYHRSCFRCKQCSCTLHSGAYKATGEPGTFVCTSHLPAA 245
Query: 219 ARLGPGTRSGTRPGPFSQPKQQHQQQLAEDAKDVPGGGPSSSAPAGAEADGPKASPEARP 278
A P P + + A++ PS+ PA +
Sbjct: 246 ASASPKLTGLVPRQPGAMGVDSRTSCSPQKAQEANKARPSAWEPAAGNS----------- 294
Query: 279 QIPTKPRVPGKLQELASPPAGRPTPAPRKASESTTPAPPTP---RPRSSLQQENLVEQAG 335
P + VP A+ +P + SES PT RPR + A
Sbjct: 295 --PARASVPAAPNPAATSATSVHVRSPARPSESRLAPTPTEGKVRPRVTNSSPMGWSSAA 352
Query: 336 SSSLVNGRLHELPVPKPRGTPKPSEGTPAPRKDPPWITLVQAEPKKKPAPLPPSSSPGPP 395
+ +P P P +G APR P TL + PP+ +P
Sbjct: 353 PCTAAAASHPAVPPSAPDPRPATPQGGGAPRVAAPQTTLSSSSTSAATVD-PPAWTPS-- 409
Query: 396 SQDSRQVENGGTEEVAQPSPTASLESKPYNP--------FEEEEEDKEEEAPAAPSLATS 447
+ ++Q N + A P P SL + P +E+ + ++A +A A +
Sbjct: 410 ASRTQQARNKFFQTSAVP-PGTSLSGRGPTPSLVLSKDSSKEQARNFLKQALSALEEAGA 468
Query: 448 PALGHPESTPKSLHPWYGITPTSSPKTKKRPAPRAPSASPLALHASRLSHSEP-----PS 502
PA G P P P+S PKT+ AP ASPL A L S P PS
Sbjct: 469 PAPGRPS-------PATAAVPSSQPKTE------APQASPL---AKPLQSSSPRVLGLPS 512
Query: 503 ATPSPA-LSVESLSSESASQTAG-AELLEPPAVPK--SSSEPAVHAPGTPGNPVSLSTNS 558
PA LS S S SA AG L E V + + S P AP G +L+ +
Sbjct: 513 RMEPPAPLSTSSTSQASALPPAGRRNLAESSGVGRVGAGSRPKPEAPMAKGKSTTLTQDM 572
Query: 559 SLA-SSGELVEP---RVEQMPQASPGLAPRTRGSSGPQP-AKPCSGATP----------- 602
S + G+ P R P A RT P+ A+P +G P
Sbjct: 573 STSLQEGQEDGPAGWRANLKPVDRRSPAERTLKPKEPRALAEPRAGEAPRKVSGSFAGSV 632
Query: 603 --TPLLLVGDRSPVP-SPGSSSP----------QLQVKSSCKENPFNRKPSPAASPA--- 646
T + DR+P P SPG S P +L V +S +P P A
Sbjct: 633 HITLTPVRPDRTPRPASPGPSLPARSPSPPRRRRLAVPASLDVCDNWLRPEPPGQEARVQ 692
Query: 647 -----TKKATKGSKPVRPPAPGHGFPLIKRKVQA-----DQYIPEEDIHGEMDTIERRLD 696
KK KP RP +P + L V + Y+ E+I ++ IERRLD
Sbjct: 693 SWKEEEKKPHLQGKPGRPLSPANVPALPGETVTSPVRLHPDYLSPEEIQRQLQDIERRLD 752
Query: 697 ALEHRGVLLEEKLRGGLNEGREDDMLVDWFKLIHEKHLLVRRESELIYVFKQQNLEQRQA 756
ALE RGV LE++LR + ED ++VDWF LIHEK LL+R+ESEL+Y K Q LE++Q
Sbjct: 753 ALELRGVELEKRLRAAEGDDAEDSLMVDWFWLIHEKQLLLRQESELMYKSKAQRLEEQQL 812
Query: 757 DVEYELRCLLNKPEKDWTEEDRAREKVLMQELVTLIEQRNAIINCLDEDRQREEEEDKML 816
D+E ELR L+ KPE + ++R RE+ L+++ V+ + R+ I++ LDEDR RE+EED+ML
Sbjct: 813 DIEGELRRLMAKPEALKSLQERRREQELLEQYVSTVNDRSDIVDSLDEDRLREQEEDQML 872
Query: 817 EAMIKKKEFQREAEPEGKKKGKFKTMKM 844
MI+K QR KK KF+ K+
Sbjct: 873 RDMIEKLGLQR-------KKSKFRLSKI 893
>gi|205360947 microtubule associated monoxygenase, calponin and LIM
domain containing 1 isoform 1 [Homo sapiens]
Length = 1067
Score = 138 bits (348), Expect = 2e-32
Identities = 100/358 (27%), Positives = 150/358 (41%), Gaps = 49/358 (13%)
Query: 2 AGPRGALLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFE 61
AG + LL WC+ Q GY GV + DLSSS+ DGLA CA+++R +P LL+ L E
Sbjct: 508 AGTQEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALE 567
Query: 62 NNRLAFEVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHF----CSPGQAGVSP 117
A +VAE ELGI ++ +V+ S P L ++ Y+S +++ F SPG +
Sbjct: 568 ATAWALKVAENELGITPVVSAQAVVAGSDP--LGLIAYLSHFHSAFKSMAHSPGPVSQAS 625
Query: 118 PRKGLAPCSPPSVAPTPVEPEDVAQGEELSSGSLSEQGTGQTPSS--------------- 162
P A + T E+ L + +TPS+
Sbjct: 626 PGTSSAVLFLSKLQRTLQRSRAKENAEDAGGKKLRLEMEAETPSTEVPPDPEPGVPLTPP 685
Query: 163 ----------TCAACQQHVHLVQRYLADGRLYHRHCFRCRRCSSTLLPGAYENGPEEGTF 212
CA C +H+++++R +G +HR CFRC C +TL PG YE P +G F
Sbjct: 686 SQHQEAGAGDLCALCGEHLYVLERLCVNGHFFHRSCFRCHTCEATLWPGGYEQHPGDGHF 745
Query: 213 VCAEHCARLGPGTRSGTRPGPFSQPKQQHQQQLAEDAKDVPGGGPSSSAPAGAEADGPKA 272
C +H + R GP ++ ++P +S P P A
Sbjct: 746 YCLQHLPQTDHKAEGSDR-GP--------------ESPELPTPSENSMPPG---LSTPTA 787
Query: 273 SPEARPQIPTKPRVPGKLQELASPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQENL 330
S E +P + + L+SP R + P P PR S+L + L
Sbjct: 788 SQEGAGPVPDPSQPTRRQIRLSSPERQRLSSLNLTPDPEMEPPPKPPRSCSALARHAL 845
Score = 77.4 bits (189), Expect = 5e-14
Identities = 74/300 (24%), Positives = 129/300 (43%), Gaps = 19/300 (6%)
Query: 524 GAELLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAP 583
G E E P ++S P + P + S + ++ E+ +S L P
Sbjct: 764 GPESPELPTPSENSMPPGLSTPTASQEGAGPVPDPSQPTRRQIRLSSPERQRLSSLNLTP 823
Query: 584 RTRGSSGPQPAKPCSGATPTPL--LLVGDRSPVPSPGSSSPQLQVKSSCKENPFNRKPSP 641
P+P + CS L VG PV SP + + ++ KE+PF+ +
Sbjct: 824 DPEMEPPPKPPRSCSALARHALESSFVGWGLPVQSPQAL---VAMEKEEKESPFSSEEEE 880
Query: 642 AASPATKKATKGSKP-VRPPAPGHGFPLIKRKV-------QADQYIPEEDIHGEMDTIER 693
P + + + + +P +R + + ++ + I ++ IE
Sbjct: 881 EDVPLDSDVEQALQTFAKTSGTMNNYPTWRRTLLRRAKEEEMKRFCKAQTIQRRLNEIEA 940
Query: 694 RLDALEHRGVLLEEKLRGGLNEGREDDMLVDW----FKLIHEKHLLVRRESELIYVFKQQ 749
L LE GV LE LR + + L W +L+ +K+ LV E+EL+ ++
Sbjct: 941 ALRELEAEGVKLELALRRQSSSPEQQKKL--WVGQLLQLVDKKNSLVAEEAELMITVQEL 998
Query: 750 NLEQRQADVEYELRCLLNKPEKDWTEEDRAREKVLMQELVTLIEQRNAIINCLDEDRQRE 809
NLE++Q ++ ELR +N+ E T DR E ++++LV L+ QR+A+I +E R E
Sbjct: 999 NLEEKQWQLDQELRGYMNREENLKTAADRQAEDQVLRKLVDLVNQRDALIRFQEERRLSE 1058
>gi|226530313 microtubule associated monoxygenase, calponin and LIM
domain containing 1 isoform 2 [Homo sapiens]
Length = 981
Score = 138 bits (348), Expect = 2e-32
Identities = 100/358 (27%), Positives = 150/358 (41%), Gaps = 49/358 (13%)
Query: 2 AGPRGALLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFE 61
AG + LL WC+ Q GY GV + DLSSS+ DGLA CA+++R +P LL+ L E
Sbjct: 422 AGTQEELLRWCQEQTAGYPGVHVSDLSSSWADGLALCALVYRLQPGLLEPSELQGLGALE 481
Query: 62 NNRLAFEVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHF----CSPGQAGVSP 117
A +VAE ELGI ++ +V+ S P L ++ Y+S +++ F SPG +
Sbjct: 482 ATAWALKVAENELGITPVVSAQAVVAGSDP--LGLIAYLSHFHSAFKSMAHSPGPVSQAS 539
Query: 118 PRKGLAPCSPPSVAPTPVEPEDVAQGEELSSGSLSEQGTGQTPSS--------------- 162
P A + T E+ L + +TPS+
Sbjct: 540 PGTSSAVLFLSKLQRTLQRSRAKENAEDAGGKKLRLEMEAETPSTEVPPDPEPGVPLTPP 599
Query: 163 ----------TCAACQQHVHLVQRYLADGRLYHRHCFRCRRCSSTLLPGAYENGPEEGTF 212
CA C +H+++++R +G +HR CFRC C +TL PG YE P +G F
Sbjct: 600 SQHQEAGAGDLCALCGEHLYVLERLCVNGHFFHRSCFRCHTCEATLWPGGYEQHPGDGHF 659
Query: 213 VCAEHCARLGPGTRSGTRPGPFSQPKQQHQQQLAEDAKDVPGGGPSSSAPAGAEADGPKA 272
C +H + R GP ++ ++P +S P P A
Sbjct: 660 YCLQHLPQTDHKAEGSDR-GP--------------ESPELPTPSENSMPPG---LSTPTA 701
Query: 273 SPEARPQIPTKPRVPGKLQELASPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQENL 330
S E +P + + L+SP R + P P PR S+L + L
Sbjct: 702 SQEGAGPVPDPSQPTRRQIRLSSPERQRLSSLNLTPDPEMEPPPKPPRSCSALARHAL 759
Score = 77.4 bits (189), Expect = 5e-14
Identities = 74/300 (24%), Positives = 129/300 (43%), Gaps = 19/300 (6%)
Query: 524 GAELLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAP 583
G E E P ++S P + P + S + ++ E+ +S L P
Sbjct: 678 GPESPELPTPSENSMPPGLSTPTASQEGAGPVPDPSQPTRRQIRLSSPERQRLSSLNLTP 737
Query: 584 RTRGSSGPQPAKPCSGATPTPL--LLVGDRSPVPSPGSSSPQLQVKSSCKENPFNRKPSP 641
P+P + CS L VG PV SP + + ++ KE+PF+ +
Sbjct: 738 DPEMEPPPKPPRSCSALARHALESSFVGWGLPVQSPQAL---VAMEKEEKESPFSSEEEE 794
Query: 642 AASPATKKATKGSKP-VRPPAPGHGFPLIKRKV-------QADQYIPEEDIHGEMDTIER 693
P + + + + +P +R + + ++ + I ++ IE
Sbjct: 795 EDVPLDSDVEQALQTFAKTSGTMNNYPTWRRTLLRRAKEEEMKRFCKAQTIQRRLNEIEA 854
Query: 694 RLDALEHRGVLLEEKLRGGLNEGREDDMLVDW----FKLIHEKHLLVRRESELIYVFKQQ 749
L LE GV LE LR + + L W +L+ +K+ LV E+EL+ ++
Sbjct: 855 ALRELEAEGVKLELALRRQSSSPEQQKKL--WVGQLLQLVDKKNSLVAEEAELMITVQEL 912
Query: 750 NLEQRQADVEYELRCLLNKPEKDWTEEDRAREKVLMQELVTLIEQRNAIINCLDEDRQRE 809
NLE++Q ++ ELR +N+ E T DR E ++++LV L+ QR+A+I +E R E
Sbjct: 913 NLEEKQWQLDQELRGYMNREENLKTAADRQAEDQVLRKLVDLVNQRDALIRFQEERRLSE 972
>gi|170172518 microtubule associated monoxygenase, calponin and LIM
domain containing 3 isoform 3 [Homo sapiens]
Length = 966
Score = 123 bits (309), Expect = 6e-28
Identities = 54/100 (54%), Positives = 77/100 (77%)
Query: 8 LLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFENNRLAF 67
LL WC+RQ +GY GV + DL+ S++ GLA CAI+HR+RPDL+DFDSL + NV +NN+LAF
Sbjct: 524 LLGWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNVEKNNQLAF 583
Query: 68 EVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHF 107
++AEKELGI ++ +M S+ PD LS++ Y++Q+Y F
Sbjct: 584 DIAEKELGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMF 623
Score = 63.9 bits (154), Expect = 6e-10
Identities = 38/126 (30%), Positives = 59/126 (46%), Gaps = 2/126 (1%)
Query: 161 SSTCAACQQHVHLVQRYLADGRLYHRHCFRCRRCSSTLLPGAYENGPEEGTFVCAEH-CA 219
S TC CQ+ V++++R A+G+ +HR CF+C C++TL AY E+G F C H C
Sbjct: 761 SDTCYFCQKRVYVMERLSAEGKFFHRSCFKCEYCATTLRLSAYAYDIEDGKFYCKPHYCY 820
Query: 220 RLGPGTRSGTRPGPFSQPKQQHQQQLAEDAKDVPGGGPSSSAPAGAEADGPKASPEARPQ 279
RL G RP ++ + L + A G ++ A + G + P
Sbjct: 821 RLS-GYAQRKRPAVAPLSGKEAKGPLQDGATTDANGRANAVASSTERTPGSGVNGLEEPS 879
Query: 280 IPTKPR 285
I + R
Sbjct: 880 IAKRLR 885
>gi|209862793 microtubule associated monoxygenase, calponin and LIM
domain containing 3 isoform 2 [Homo sapiens]
Length = 1073
Score = 123 bits (309), Expect = 6e-28
Identities = 54/100 (54%), Positives = 77/100 (77%)
Query: 8 LLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFENNRLAF 67
LL WC+RQ +GY GV + DL+ S++ GLA CAI+HR+RPDL+DFDSL + NV +NN+LAF
Sbjct: 524 LLGWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNVEKNNQLAF 583
Query: 68 EVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHF 107
++AEKELGI ++ +M S+ PD LS++ Y++Q+Y F
Sbjct: 584 DIAEKELGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMF 623
Score = 62.4 bits (150), Expect = 2e-09
Identities = 36/114 (31%), Positives = 55/114 (48%), Gaps = 2/114 (1%)
Query: 161 SSTCAACQQHVHLVQRYLADGRLYHRHCFRCRRCSSTLLPGAYENGPEEGTFVCAEH-CA 219
S TC CQ+ V++++R A+G+ +HR CF+C C++TL AY E+G F C H C
Sbjct: 885 SDTCYFCQKRVYVMERLSAEGKFFHRSCFKCEYCATTLRLSAYAYDIEDGKFYCKPHYCY 944
Query: 220 RLGPGTRSGTRPGPFSQPKQQHQQQLAEDAKDVPGGGPSSSAPAGAEADGPKAS 273
RL G RP ++ + L + A G ++ A + G S
Sbjct: 945 RLS-GYAQRKRPAVAPLSGKEAKGPLQDGATTDANGRANAVASSTERTPGSLTS 997
>gi|209862789 microtubule associated monoxygenase, calponin and LIM
domain containing 3 isoform 1 [Homo sapiens]
Length = 2002
Score = 123 bits (309), Expect = 6e-28
Identities = 54/100 (54%), Positives = 77/100 (77%)
Query: 8 LLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFENNRLAF 67
LL WC+RQ +GY GV + DL+ S++ GLA CAI+HR+RPDL+DFDSL + NV +NN+LAF
Sbjct: 524 LLGWCQRQTDGYAGVNVTDLTMSWKSGLALCAIIHRYRPDLIDFDSLDEQNVEKNNQLAF 583
Query: 68 EVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHF 107
++AEKELGI ++ +M S+ PD LS++ Y++Q+Y F
Sbjct: 584 DIAEKELGISPIMTGKEMASVGEPDKLSMVMYLTQFYEMF 623
Score = 123 bits (309), Expect = 6e-28
Identities = 176/663 (26%), Positives = 266/663 (40%), Gaps = 104/663 (15%)
Query: 254 GGGPSSSAPAGAEADGPKASPEARPQIP----TKP-RVPGKLQELASPPAGRPTPAPRKA 308
G PS PA S E PQ KP +P +L P G P P
Sbjct: 1348 GPEPSFPTPAFRPVSLKSYSVEKSPQDEGLHLLKPLSIPKRLG--LPKPEGEPLSLPTPR 1405
Query: 309 SESTTPAPPTPRPRSSLQQENLVEQAGSSSLVNG------RLHELPVPKPRGTPKPSEGT 362
S S R L + + GSSS + + + P +P P
Sbjct: 1406 SPSDRELRSAQEERRELSSSSGLGLHGSSSNMKTLGSQSFNTSDSAMLTPPSSPPPP--- 1462
Query: 363 PAPRKDPPWIT--LVQAEPKKK--PAPLPPS--SSPGPPSQDSRQVENGGTEEVAQPSPT 416
P P ++P + L +AEP P PLP + P P+Q R+ E + P
Sbjct: 1463 PPPGEEPATLRRKLREAEPNASVVPPPLPATWMRPPREPAQPPREEVRKSFVESVEEIPF 1522
Query: 417 ASLESKPYNPFEEEEEDKEE-----------EAPAAPSLATSPALGHPESTPKSLHPWYG 465
A Y+ E+ +E+ E P P LA G + +L P
Sbjct: 1523 ADDVEDTYDDKTEDSSLQEKFFTPPSCWPRPEKPRHPPLAKEN--GRLPALEGTLQPQKR 1580
Query: 466 ITPTSSPKTKK----RPAPRAPSASPLALH------ASRLSHSEPPSATPSP--ALSVES 513
P S + K+ R R S AL SR+ E S P P A S S
Sbjct: 1581 GLPLVSAEAKELAEERMRAREKSVKSQALRDAMARQLSRMQQMELASGAPRPRKASSAPS 1640
Query: 514 LSSESASQTAGAELL----EPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGE---- 565
E + L EP +++SE + P G P S SS SSG+
Sbjct: 1641 QGKERRPDSPTRPTLRGSEEPTLKHEATSEEVLSPPSDSGGPDG-SFTSSEGSSGKSKKR 1699
Query: 566 --LVEPRVEQMPQASPGLA-PRTRGSSG---PQPAKP-------CSGATPTPLLLVGDRS 612
L PR + + S G P + SS AKP SG D+S
Sbjct: 1700 SSLFSPRRNKKEKKSKGEGRPPEKPSSNLLEEAAAKPKSLWKSVFSGYKKDKKKKADDKS 1759
Query: 613 PVPSPGSSSP--------------QLQVKSSCKENPFNRKPSPAASPATKKATKGSKPVR 658
+P S + +LQ++ ++ F+ ++ +K+++ S+ R
Sbjct: 1760 CPSTPSSGATVDSGKHRVLPVVRAELQLR---RQLSFSEDSDLSSDDVLEKSSQKSR--R 1814
Query: 659 PPAPGHGFPL---IKRKVQ--ADQYIPEED---------IHGEMDTIERRLDALEHRGVL 704
P L + R+VQ A + +E+ I ++ +E R LE RGV
Sbjct: 1815 EPRTYTEEELNAKLTRRVQKAARRQAKQEELKRLHRAQIIQRQLQQVEERQRRLEERGVA 1874
Query: 705 LEEKLRGGLNEGREDD--MLVDWFKLIHEKHLLVRRESELIYVFKQQNLEQRQADVEYEL 762
+E+ LRG G++DD ++ +WFKL+ EK+ +VR ESEL+ ++ LE RQ+ ++ EL
Sbjct: 1875 VEKALRGEAGMGKKDDPKLMQEWFKLVQEKNAMVRYESELMIFARELELEDRQSRLQQEL 1934
Query: 763 RCLLNKPEKDWTEEDRAREKVLMQELVTLIEQRNAIINCLDEDRQREEEEDKMLEAMIKK 822
R + + TEE+ + EK ++ E++ ++EQR++++ L+E R RE EEDK LEA +
Sbjct: 1935 RERMAVEDHLKTEEELSEEKQILNEMLEVVEQRDSLVALLEEQRLREREEDKDLEAAMLS 1994
Query: 823 KEF 825
K F
Sbjct: 1995 KGF 1997
Score = 88.6 bits (218), Expect = 2e-17
Identities = 133/566 (23%), Positives = 198/566 (34%), Gaps = 88/566 (15%)
Query: 161 SSTCAACQQHVHLVQRYLADGRLYHRHCFRCRRCSSTLLPGAYENGPEEGTFVCAEH-CA 219
S TC CQ+ V++++R A+G+ +HR CF+C C++TL AY E+G F C H C
Sbjct: 761 SDTCYFCQKRVYVMERLSAEGKFFHRSCFKCEYCATTLRLSAYAYDIEDGKFYCKPHYCY 820
Query: 220 RLGPGTRSGTRPGPFSQPKQQHQQQLAEDAKDVPGGGPSSSAPAGAEADGPKASPEARPQ 279
RL G RP ++ + L + A G ++ A + G + P
Sbjct: 821 RLS-GYAQRKRPAVAPLSGKEAKGPLQDGATTDANGRANAVASSTERTPGSGVNGLEEPS 879
Query: 280 IPTKPR-VPGKLQELASPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQENLVEQAGSSS 338
I + R P +++ + R A ++ E T + +E++ + S
Sbjct: 880 IAKRLRGTPERIELENYRLSLRQAEALQEVPEETQAEHNLSSVLDTGAEEDVASSSSESE 939
Query: 339 LVNGRLHELPVPKPRGTPKPSEGTPAPRKDPPWITLVQAE---PKKKPAPLPPSSSPGPP 395
+ E +PR P G PW V+ K L S S GP
Sbjct: 940 MEEEGEEE--EEEPRLPPSDLGGV-------PWKEAVRIHALLKGKSEEELEASKSFGPG 990
Query: 396 SQDSRQVENGGTEEVAQPSPTASLESK------------PYNPFE----------EEEED 433
+++ + E EE + ES +P E E E+
Sbjct: 991 NEEEEEEEEEYEEEEEEDYDEEEEESSEAGNQRLQQVMHAADPLEIQADVHWTHIREREE 1050
Query: 434 KEEEAPAAPSLATSPAL-----------------------GHPESTPKSL--HPWYGITP 468
+E APA+ S A+ L G P T L + +P
Sbjct: 1051 EERMAPASESSASGAPLDENDLEEDVDSEPAEIEGEAAEDGDPGDTGAELDDDQHWSDSP 1110
Query: 469 TSSPKTKKRPAPRAPSASPLALHASRLSHSEPPSAT-----PSPALSVESLSSESA---- 519
+ + + + P P A + L L S P S PS A S ESA
Sbjct: 1111 SDADRELRLPCP-AEGEAELELRVSEDEEKLPASPKHQERGPSQATSPIRSPQESALLFI 1169
Query: 520 ----SQTAGAELLEPPAV--PKSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQ 573
T G +L PA KS E P P S L + + +
Sbjct: 1170 PVHSPSTEGPQLPPVPAATQEKSPEERLFPEPLLPKEKPKADAPSDLKAVHSPIRSQPVT 1229
Query: 574 MPQASPGLAPRTRGSSGPQPAKPCSGATPTPLLLVGDRSP-----VPSPGSSSPQLQVKS 628
+P+A ++P GS PQP S P+PL + P VPSP S + Q
Sbjct: 1230 LPEARTPVSP---GSPQPQPPVAASTPPPSPLPICSQPQPSTEATVPSPTQSPIRFQPAP 1286
Query: 629 SCKENPFNRKPSPAASPATKKATKGS 654
+ P P P S + K GS
Sbjct: 1287 AKTSTPL--APLPVQSQSDTKDRLGS 1310
Score = 63.2 bits (152), Expect = 1e-09
Identities = 104/439 (23%), Positives = 163/439 (37%), Gaps = 53/439 (12%)
Query: 262 PAGAEADGPKASPEARPQIPTKPRVPGKLQELASPPAGRPTPAPRKAS-------ESTTP 314
PA EA+ E ++P P K QE A P +P++++ +T
Sbjct: 1122 PAEGEAELELRVSEDEEKLPASP----KHQERGPSQATSPIRSPQESALLFIPVHSPSTE 1177
Query: 315 APPTPRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKPRG-TPKPSEGTPAPRKDPPWIT 373
P P ++ Q+++ E+ L LP KP+ P + +P + P +T
Sbjct: 1178 GPQLPPVPAATQEKSPEERLFPEPL-------LPKEKPKADAPSDLKAVHSPIRSQP-VT 1229
Query: 374 LVQAEPKKKPA---PLPPSSSPGPPSQDSRQVENGGTEEVAQPSPTASLESKPYNPFEEE 430
L +A P P PP ++ PP QPS A++ S +P +
Sbjct: 1230 LPEARTPVSPGSPQPQPPVAASTPPPSPLPICSQ------PQPSTEATVPSPTQSPIRFQ 1283
Query: 431 EEDKEEEAPAAP-----SLATSPALGHPESTPKSLHPWYGITPTSSPKTKKRPAPRAPSA 485
+ P AP T LG P + ++L + + R R+
Sbjct: 1284 PAPAKTSTPLAPLPVQSQSDTKDRLGSPLAVDEALRRSDLVEEFWMKSAEIR---RSLGL 1340
Query: 486 SPLALHASRLSHSEPPSATPS-PALSVESLSSESASQTAGAELLEPPAVPKSSSEPAVHA 544
+P+ R EP TP+ +S++S S E + Q G LL+P ++PK +
Sbjct: 1341 TPV----DRSKGPEPSFPTPAFRPVSLKSYSVEKSPQDEGLHLLKPLSIPK-----RLGL 1391
Query: 545 PGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAPRTRGSSGPQPAKPCSGATPTP 604
P G P+SL T S S EL + E+ +S SS + S T
Sbjct: 1392 PKPEGEPLSLPTPRS-PSDRELRSAQEERRELSSSSGLGLHGSSSNMKTLGSQSFNTSDS 1450
Query: 605 LLLVGDRSPVPSPGSSSPQLQVKSSCKENPFNRKPSPAASPATKKATKGSKPVRPPAPGH 664
+L SP P P ++ +E N P PAT +P R PA
Sbjct: 1451 AMLTPPSSPPPPPPPGEEPATLRRKLREAEPNASVVPPPLPAT-----WMRPPREPAQPP 1505
Query: 665 GFPLIKRKVQADQYIPEED 683
+ K V++ + IP D
Sbjct: 1506 REEVRKSFVESVEEIPFAD 1524
>gi|7662284 microtubule associated monoxygenase, calponin and LIM
domain containing 2 [Homo sapiens]
Length = 1124
Score = 117 bits (294), Expect = 4e-26
Identities = 57/128 (44%), Positives = 85/128 (66%)
Query: 8 LLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFENNRLAF 67
LL WC++Q EGY+ V + DL++S+R GLA CAI+HR RP+L++FDSL++D+ ENN+LAF
Sbjct: 522 LLTWCQQQTEGYQHVNVTDLTTSWRSGLALCAIIHRFRPELINFDSLNEDDAVENNQLAF 581
Query: 68 EVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHFCSPGQAGVSPPRKGLAPCSP 127
+VAE+E GIP + +M S PD LS++ Y+S++Y F V RK +
Sbjct: 582 DVAEREFGIPPVTTGKEMASAQEPDKLSMVMYLSKFYELFRGTPLRPVDSWRKNYGENAD 641
Query: 128 PSVAPTPV 135
S+A + +
Sbjct: 642 LSLAKSSI 649
Score = 63.9 bits (154), Expect = 6e-10
Identities = 36/122 (29%), Positives = 60/122 (49%), Gaps = 4/122 (3%)
Query: 161 SSTCAACQQHVHLVQRYLADGRLYHRHCFRCRRCSSTLLPGAYENGPEEGTFVCAEHCAR 220
S TC C++ V++++R A+G +HR CFRC C++TL AY +EG F C H
Sbjct: 999 SDTCYFCKKRVYVMERLSAEGHFFHRECFRCSICATTLRLAAYTFDCDEGKFYCKPHFIH 1058
Query: 221 LGPGTRSGTRPGPFSQPKQQHQQQLAEDAKDVP-GGGPSSSAPAGAEADGPKASPEARPQ 279
++ R ++ KQQ +++ ++ P P+ S+ A A + SP
Sbjct: 1059 CKTNSKQRKRR---AELKQQREEEATWQEQEAPRRDTPTESSCAVAAIGTLEGSPPVHFS 1115
Query: 280 IP 281
+P
Sbjct: 1116 LP 1117
>gi|5902122 spectrin, beta, non-erythrocytic 2 [Homo sapiens]
Length = 2390
Score = 113 bits (282), Expect = 9e-25
Identities = 58/117 (49%), Positives = 78/117 (66%), Gaps = 1/117 (0%)
Query: 5 RGALLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFENNR 64
+ ALL WC+ + GY V + + ++S+RDGLAF AI+H+HRPDLLDF+SL K N N +
Sbjct: 179 KDALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRPDLLDFESLKKCNAHYNLQ 238
Query: 65 LAFEVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHFCSPGQAGVSPPRKG 121
AF +AEKELG+ LLDP D V++ PD SI+TYV+ YY++F V R G
Sbjct: 239 NAFNLAEKELGLTKLLDPED-VNVDQPDEKSIITYVATYYHYFSKMKALAVEGKRIG 294
>gi|4501893 actinin, alpha 2 [Homo sapiens]
Length = 894
Score = 112 bits (280), Expect = 1e-24
Identities = 53/112 (47%), Positives = 74/112 (66%)
Query: 8 LLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFENNRLAF 67
LL WC+R+ YR V I++ +S++DGL CA++HRHRPDL+D+ L+KD+ N LA
Sbjct: 157 LLLWCQRKTAPYRNVNIQNFHTSWKDGLGLCALIHRHRPDLIDYSKLNKDDPIGNINLAM 216
Query: 68 EVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHFCSPGQAGVSPPR 119
E+AEK L IP +LD D+V+ PD +IMTYVS +Y+ F QA + R
Sbjct: 217 EIAEKHLDIPKMLDAEDIVNTPKPDERAIMTYVSCFYHAFAGAEQAETAANR 268
>gi|4557241 actinin, alpha 3 [Homo sapiens]
Length = 901
Score = 112 bits (279), Expect = 2e-24
Identities = 54/112 (48%), Positives = 74/112 (66%)
Query: 8 LLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFENNRLAF 67
LL WC+R+ YR V +++ +S++DGLA CA++HRHRPDL+D+ L KD+ N AF
Sbjct: 164 LLLWCQRKTAPYRNVNVQNFHTSWKDGLALCALIHRHRPDLIDYAKLRKDDPIGNLNTAF 223
Query: 68 EVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHFCSPGQAGVSPPR 119
EVAEK L IP +LD D+V+ PD +IMTYVS +Y+ F QA + R
Sbjct: 224 EVAEKYLDIPKMLDAEDIVNTPKPDEKAIMTYVSCFYHAFAGAEQAETAANR 275
>gi|150378549 tangerin [Homo sapiens]
Length = 1523
Score = 110 bits (276), Expect = 4e-24
Identities = 99/332 (29%), Positives = 138/332 (41%), Gaps = 59/332 (17%)
Query: 7 ALLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFENNRLA 66
+LL WC+ GYRGV I + ++S+R+GLAFCAILHR PD +D+ SL N+ +NN+ A
Sbjct: 1042 SLLEWCQEVTTGYRGVRITNFTTSWRNGLAFCAILHRFYPDKIDYASLDPLNIKQNNKQA 1101
Query: 67 FEVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHFCS---------PGQAGVSP 117
F+ LG+ LL+P DMV +SVPD L +MTY+ Q FC+ G G
Sbjct: 1102 FD-GFAALGVSRLLEPADMVLLSVPDKLIVMTYLCQ-IRAFCTGQELQLVQLEGGGGAGT 1159
Query: 118 PRKGLAPCSPPS--------------VAPTPVEPEDVAQ----------GEELSSGSLSE 153
R G A SPP A P EP++ A +G S+
Sbjct: 1160 YRVGSAQPSPPDDLDAGGLAQRLRGHGAEGPQEPKEAADRADGAAPGVASRNAVAGRASK 1219
Query: 154 QGTGQTPSSTCAACQQHVHLVQRYLADGRLYHRHCFRCRRCSSTLLPGAYENGPEEGTFV 213
G + P + A LV A G R RR S PG+ G+F
Sbjct: 1220 DGGAEAPRESRPAEVPAEGLVNGAGAPG----GGGVRLRRPSVNGEPGSVPPPRAHGSF- 1274
Query: 214 CAEHCARLGPGTRSGTRPGPFSQPKQQHQQQLAEDAKDVPGGGPSSSAPAGAEADGPKAS 273
S R + ++ + + + D P G +A A +A P +
Sbjct: 1275 -------------SHVRDADLLKKRRSRLRNSSSFSMDDPDAGAMGAAAAEGQAPDPSPA 1321
Query: 274 PEARPQIPTKPRVPGKLQELASPPAGRPTPAP 305
P P + PG S P+ P P+P
Sbjct: 1322 P-GPPTAADSQQPPG-----GSSPSEEPPPSP 1347
Score = 93.6 bits (231), Expect = 7e-19
Identities = 89/363 (24%), Positives = 163/363 (44%), Gaps = 57/363 (15%)
Query: 472 PKTKKRPAPRAPSASP-------LALHASRLSHSEPPSATPSPALSVESLSSESASQTAG 524
P+ K A RA A+P +A AS+ +E P + + E L + + + G
Sbjct: 1190 PQEPKEAADRADGAAPGVASRNAVAGRASKDGGAEAPRESRPAEVPAEGLVNGAGAPGGG 1249
Query: 525 AELLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAPR 584
L P+V PG+ P + + S + + L + R +S +
Sbjct: 1250 GVRLRRPSVNGE--------PGSVPPPRAHGSFSHVRDADLLKKRRSRLRNSSSFSMDDP 1301
Query: 585 TRGSSGPQPAKPCSGATPTPLLLVGDRSPVPSPGSSSPQLQVKSSCKENPFNRKPSPAAS 644
G+ G A+ G P P SP P P +++ Q P +S
Sbjct: 1302 DAGAMGAAAAE---GQAPDP-------SPAPGPPTAADSQQ-------------PPGGSS 1338
Query: 645 PATKKATKGSKPVRPPAPGHGFPLIKRKVQADQYIPEEDIHGEMDTIERRLDALEHRGVL 704
P+ + PP+PG L +R QY+ E+ +E+ ++ R
Sbjct: 1339 PSEEP---------PPSPGEEAGL-QRFQDTSQYVC-----AELQALEQEQRQIDGRAAE 1383
Query: 705 LEEKLRG----GLNEGREDDMLVDWFKLIHEKHLLVRRESELIYVFKQQNLEQRQADVEY 760
+E +LR G N+ +E+ ++ +WF L+++K+ L+RR+ +L + ++Q+LE+R +
Sbjct: 1384 VEMQLRSLMESGANKLQEEVLIQEWFTLVNKKNALIRRQDQLQLLMEEQDLERRFELLSR 1443
Query: 761 ELRCLLNKPEKDWTEEDRAREKVLMQELVTLIEQRNAIINCLDEDRQREEEEDKMLEAMI 820
ELR +L + T + RE++L++ELV+L+ QR+ ++ LD + EED+ LE +
Sbjct: 1444 ELRAMLAIEDWQKTSAQQHREQLLLEELVSLVNQRDELVRDLDHKERIALEEDERLERGL 1503
Query: 821 KKK 823
+++
Sbjct: 1504 EQR 1506
Score = 42.7 bits (99), Expect = 0.001
Identities = 62/271 (22%), Positives = 92/271 (33%), Gaps = 33/271 (12%)
Query: 413 PSPTASLESKPYNPFEEEEEDKEEEAPAAPSLA--TSPALGHPESTPKSLHPWYGITPTS 470
P P S E K EEE + + ++A A+PS A TSPA + P G +
Sbjct: 209 PQPDPSRELKTLCEEEEEGQGRPQQAVASPSNAEDTSPAPVSAPAPPARTSRGQGSERAN 268
Query: 471 SPKTKKRP-APRAPSASPLALHASRLSHSEPPSATPSPALSVESLSSESASQTAGAELLE 529
+ P APR P SP + +SR ++ + TP+P L G++ L
Sbjct: 269 EAGGQVGPEAPRPPETSP-EMRSSR-QPAQDTAPTPAPRL------------RKGSDALR 314
Query: 530 PPA------VPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASP---- 579
PP VPK+S P + G + P +E P
Sbjct: 315 PPVPQGEDEVPKASGAPPAGLGSARETQAQACPQEGTEAHGARLGPSIEDKGSGDPFGRQ 374
Query: 580 -----GLAPRTRGSSGPQPAKPCSGATPTPLLLVGDRSPVPSPGSSSPQLQVKSSCKENP 634
+ R + +P SG G R+ S+ Q+ + K
Sbjct: 375 RLKAEEMDTEDRPEASGVDTEPRSGGREANTKRSGVRAGEAEESSAVCQVDAEQRSKVRH 434
Query: 635 FNRKPSPAASPATKKATKGSKPVRPPAPGHG 665
+ K P A+ +A P PP G
Sbjct: 435 VDTK-GPEATGVMPEARCRGTPEAPPRGSQG 464
Score = 37.4 bits (85), Expect = 0.060
Identities = 41/164 (25%), Positives = 62/164 (37%), Gaps = 25/164 (15%)
Query: 281 PTKPRVPGKLQELASPP-AGRPTPAPRKASESTTPAPPTPRPRSSLQQENLVEQAGSSS- 338
P +P+ + A+P A R A R + + AP RP + + E LV AG+
Sbjct: 1190 PQEPKEAADRADGAAPGVASRNAVAGRASKDGGAEAPRESRP-AEVPAEGLVNGAGAPGG 1248
Query: 339 --------LVNGRLHELPVPKPRGTPKPSEGTPAPRK-------------DPPWITLVQA 377
VNG +P P+ G+ +K D P + A
Sbjct: 1249 GGVRLRRPSVNGEPGSVPPPRAHGSFSHVRDADLLKKRRSRLRNSSSFSMDDPDAGAMGA 1308
Query: 378 EPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQPSPTASLES 421
+ AP PS +PGPP+ Q GG+ +P P+ E+
Sbjct: 1309 AAAEGQAP-DPSPAPGPPTAADSQQPPGGSSPSEEPPPSPGEEA 1351
Score = 36.6 bits (83), Expect = 0.10
Identities = 31/98 (31%), Positives = 41/98 (41%), Gaps = 6/98 (6%)
Query: 246 AEDAKDVPGGGPSSSAPAGAEADGPKASPEARPQI-PTKPRVPGKLQELASP--PAG--R 300
AED P P+ A + G + + EA Q+ P PR P E+ S PA
Sbjct: 241 AEDTSPAPVSAPAPPART-SRGQGSERANEAGGQVGPEAPRPPETSPEMRSSRQPAQDTA 299
Query: 301 PTPAPRKASESTTPAPPTPRPRSSLQQENLVEQAGSSS 338
PTPAPR S PP P+ + + + AG S
Sbjct: 300 PTPAPRLRKGSDALRPPVPQGEDEVPKASGAPPAGLGS 337
Score = 31.2 bits (69), Expect = 4.3
Identities = 29/118 (24%), Positives = 42/118 (35%), Gaps = 12/118 (10%)
Query: 207 PEEGTFVCAEHCARLGPGTRSGTRPGPFSQPKQQHQQQLAEDAKDVPG-------GGPSS 259
P+EGT H ARLGP PF + + + ++ ED + G GG +
Sbjct: 347 PQEGT---EAHGARLGPSIEDKGSGDPFGRQRLKAEEMDTEDRPEASGVDTEPRSGGREA 403
Query: 260 SAPAGAEADGPKASPEARPQIPTKPRVPGKLQELASPPAGRPTPAPRKASESTTPAPP 317
+ G A Q+ + R + + P A P R T APP
Sbjct: 404 NTKRSGVRAGEAEESSAVCQVDAEQRSKVRHVDTKGPEATGVMPEAR--CRGTPEAPP 459
>gi|194097352 actinin, alpha 1 isoform c [Homo sapiens]
Length = 887
Score = 110 bits (275), Expect = 6e-24
Identities = 66/179 (36%), Positives = 95/179 (53%), Gaps = 7/179 (3%)
Query: 8 LLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFENNRLAF 67
LL WC+R+ Y+ V I++ S++DGL FCA++HRHRP+L+D+ L KD+ N AF
Sbjct: 150 LLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTNLNTAF 209
Query: 68 EVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHFCSPGQAGVSPPRKGLAPCSP 127
+VAEK L IP +LD D+V + PD +IMTYVS +Y+ F +A + R C
Sbjct: 210 DVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAFSGAQKAETAANR----IC-- 263
Query: 128 PSVAPTPVEPEDVAQGEELSSGSLSEQGTGQTPSSTCAACQQHVHLVQRYLADGRLYHR 186
V E E + + E + L E P + +H +Q+ L D R Y R
Sbjct: 264 -KVLAVNQENEQLMEDYEKLASDLLEWIRRTIPWLENRVPENTMHAMQQKLEDFRDYRR 321
>gi|194097350 actinin, alpha 1 isoform a [Homo sapiens]
Length = 914
Score = 110 bits (275), Expect = 6e-24
Identities = 66/179 (36%), Positives = 95/179 (53%), Gaps = 7/179 (3%)
Query: 8 LLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFENNRLAF 67
LL WC+R+ Y+ V I++ S++DGL FCA++HRHRP+L+D+ L KD+ N AF
Sbjct: 150 LLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTNLNTAF 209
Query: 68 EVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHFCSPGQAGVSPPRKGLAPCSP 127
+VAEK L IP +LD D+V + PD +IMTYVS +Y+ F +A + R C
Sbjct: 210 DVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAFSGAQKAETAANR----IC-- 263
Query: 128 PSVAPTPVEPEDVAQGEELSSGSLSEQGTGQTPSSTCAACQQHVHLVQRYLADGRLYHR 186
V E E + + E + L E P + +H +Q+ L D R Y R
Sbjct: 264 -KVLAVNQENEQLMEDYEKLASDLLEWIRRTIPWLENRVPENTMHAMQQKLEDFRDYRR 321
>gi|4501891 actinin, alpha 1 isoform b [Homo sapiens]
Length = 892
Score = 110 bits (275), Expect = 6e-24
Identities = 66/179 (36%), Positives = 95/179 (53%), Gaps = 7/179 (3%)
Query: 8 LLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFENNRLAF 67
LL WC+R+ Y+ V I++ S++DGL FCA++HRHRP+L+D+ L KD+ N AF
Sbjct: 150 LLLWCQRKTAPYKNVNIQNFHISWKDGLGFCALIHRHRPELIDYGKLRKDDPLTNLNTAF 209
Query: 68 EVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHFCSPGQAGVSPPRKGLAPCSP 127
+VAEK L IP +LD D+V + PD +IMTYVS +Y+ F +A + R C
Sbjct: 210 DVAEKYLDIPKMLDAEDIVGTARPDEKAIMTYVSSFYHAFSGAQKAETAANR----IC-- 263
Query: 128 PSVAPTPVEPEDVAQGEELSSGSLSEQGTGQTPSSTCAACQQHVHLVQRYLADGRLYHR 186
V E E + + E + L E P + +H +Q+ L D R Y R
Sbjct: 264 -KVLAVNQENEQLMEDYEKLASDLLEWIRRTIPWLENRVPENTMHAMQQKLEDFRDYRR 321
>gi|170016061 spectrin, beta, non-erythrocytic 5 [Homo sapiens]
Length = 3639
Score = 109 bits (273), Expect = 1e-23
Identities = 60/114 (52%), Positives = 72/114 (63%), Gaps = 2/114 (1%)
Query: 7 ALLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFENNRLA 66
ALL WC+R+ Y V I D S S+ DGL F A++H HRPDLLD+ SL D N A
Sbjct: 147 ALLVWCQRKTASYTNVNITDFSRSWSDGLGFNALIHAHRPDLLDYGSLRPDRPLHNLAFA 206
Query: 67 FEVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHFCSPGQAGVSPPRK 120
F VAE+ELGI LLDP D V+ + PD SIMTYVS YY H+CS G + R+
Sbjct: 207 FLVAEQELGIAQLLDPED-VAAAQPDERSIMTYVSLYY-HYCSRLHQGQTVQRR 258
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 108 bits (271), Expect = 2e-23
Identities = 134/474 (28%), Positives = 190/474 (40%), Gaps = 55/474 (11%)
Query: 219 ARLGPGTRSGTR-PGPFSQPKQQHQQ-----QLAEDAKDV-PGGGPSSSAPAGAEADGPK 271
AR GP R R P SQPK + Q Q+ KD P GP SS+P +
Sbjct: 253 ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAA 312
Query: 272 ASPEARPQIPTKPRVPGKLQELASP-PAGRPTPAPRKASESTTPAPP-TPRPRSSLQQEN 329
+A P +P P +LA+P P P+P+ S T P+PP TP +++ +
Sbjct: 313 LQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSA-PPSLQTLPSPPATPPSQATTSLGS 371
Query: 330 LVEQAGSSSLVNGRLHELPVPKPRGTP----KPSEGTPAPRKDPPWITLVQAEPKKKPAP 385
QA S L + L L P P+ P P + P+P P P
Sbjct: 372 PTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASP---------------P 416
Query: 386 LPPSSSPGPPSQDSRQVENGGTEEVAQPSPTASLE-SKPYNPFEEEEEDKEEEAP---AA 441
L P ++P P + ++ V PSP S P +P +AP AA
Sbjct: 417 LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 476
Query: 442 PSLATSPA-LGHPESTPKSLHPWYGITPTSSPKTK-KRPAPRAPSA---SPL-ALHASRL 495
P L P+ P +P + P P ++P + +P P+AP A PL AL +
Sbjct: 477 PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPA 536
Query: 496 SHSEPPSATPSPALSVESLSS--ESASQTAGAELLE-PPAVPKSSSEPAVHAPGTPGNPV 552
S +PS +L + L++ A A LL+ PP+ P S + A P TPG
Sbjct: 537 SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT 596
Query: 553 SLSTNSSLASSGELVEPRVEQMPQASPGLAPRTRGSSGPQPAKPCSGATPTPLLLVG-DR 611
S+ SG + + P P +P + SGP A S AT TP L G D
Sbjct: 597 SV--------SGPRLTLALAPGPPPPPSRSPSST-LSGPDLAGHSSSATSTPEELRGYDS 647
Query: 612 SPVPSPGSSSPQLQVKSSCKENPFNRKPSPAASPATKKATKGSKPVRPPAPGHG 665
P +S P ++C ++R P+P P + G+ PPA G G
Sbjct: 648 GPEGGAAASPPPDAELAACHPAAWSRGPAP---PLAFRGAPGAPLPWPPATGPG 698
Score = 97.1 bits (240), Expect = 6e-20
Identities = 132/513 (25%), Positives = 178/513 (34%), Gaps = 108/513 (21%)
Query: 223 PGTRSGT-RPGPFSQPKQQHQQQLAEDAKDVPGGGPSSSAPAGAEADGPKASPEARPQIP 281
PG SGT RPGP Q + L A++ G ++ AP + + P
Sbjct: 117 PGRASGTTRPGPLGQ------KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG 170
Query: 282 TKPRVPGKLQELASPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQ-------------- 327
T + A G P PAP S P PPT PR S+
Sbjct: 171 TPSPAMARRSRAAGTEVGLPRPAP-----SARPRPPTEGPRKSVSSASEHSTTEPSPAAR 225
Query: 328 ---------ENLVEQAGSSSLVNGRLHELPVPKPRGTPK----PSEGTP----------- 363
+ ++ SSS P RGTP+ PS+ P
Sbjct: 226 RRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV 285
Query: 364 -APRKD-PPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQPSPTASLES 421
PRKD P + + + P P+P S PP+ + + T ++A P P A
Sbjct: 286 TPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLA---- 341
Query: 422 KPYNPFEEEEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPTSSPKTKKRPAPR 481
P +P PA P + +LG P T ++ H + P S T AP
Sbjct: 342 -PPSPSAPPSLQTLPSPPATPPSQATTSLGSP--TLQATHSFLPSPPLSPLATPPPQAPP 398
Query: 482 APSASPLALHASRLSHSEPPSATPSPALSVESLSSESASQTAGAELLEPPAVPKSSSEPA 541
A + PL PPS SP LS + S A LL+ P P S P
Sbjct: 399 ALALPPL---------QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS--PP 447
Query: 542 VHAPGTP--GNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAPRTRGSSGPQPAKPCSG 599
V AP +P PVS S + L P + Q+P + P P + ++ P A P
Sbjct: 448 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPL-QVPPSPPASPPMSPSATPPPQAPPPLA 506
Query: 600 ATPTPLLLVGDRSP----------VPSPGSS-------SPQLQVKSSCKENP-------- 634
A P L ++P +PSP +S SP + S P
Sbjct: 507 APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL 566
Query: 635 ----FNRKPSPAASPATKKATKGSKPVRPPAPG 663
PSP ASP + P RPP PG
Sbjct: 567 AAPLLQVPPSPPASPTLQ------APRRPPTPG 593
Score = 91.3 bits (225), Expect = 4e-18
Identities = 136/497 (27%), Positives = 187/497 (37%), Gaps = 95/497 (19%)
Query: 242 QQQLAEDAKDVPGGGPSSSAPAGAEADGPKASPEARPQIPTKPRVPGKLQELASPPAGRP 301
++ LAE A GG ++ P A GP S + P R P + +PPA
Sbjct: 55 RKPLAERA----GGIGGATIPESAPRAGPTRSAGTSSRNPAS-RPPASGRGERAPPAKNT 109
Query: 302 TP----APRKASESTTPAPPTPRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKP----- 352
+P +P +AS +T P P L Q+ L A ++ G+ E P
Sbjct: 110 SPGPVSSPGRASGTTRPGP--------LGQKGLRISA-EETVARGKATEAPKRSALSAGA 160
Query: 353 -RGTPKPSEGTPAPRKDPPWITLVQAEPKKKPAPLP-PSSSPGPPSQDSRQ-VENGGTEE 409
R T P+ GTP+P +A + P P PS+ P PP++ R+ V +
Sbjct: 161 RRDTSGPTPGTPSPAM----ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHS 216
Query: 410 VAQPSPTASLESKPYNPFEEEEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPT 469
+PSP A + PA+ SL++S P S+P P TP
Sbjct: 217 TTEPSPAARRRPSAGGGLQR---------PASRSLSSSAT---PLSSPARSGPSARGTPR 264
Query: 470 -----SSPKTKKRPAPRAPSASPLALHASRLSH--SEPPSATPSPALSVES-------LS 515
S PK K A R P +P A+ S P ATPSP+ +++S +
Sbjct: 265 APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPAT 324
Query: 516 SESASQTAGAELLEPPAVPKSSSEPAVHA----PGTP--------GNPVSLSTNSSLASS 563
S+S T P A P S+ P++ P TP G+P +T+S L S
Sbjct: 325 PHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSP 384
Query: 564 GELVEPRVEQMPQASPGLA-PRTRGSSGPQPAKPCSG-ATPTPL--------LLVGDRSP 613
+ P PQA P LA P + P + P S ATP+P LL SP
Sbjct: 385 P--LSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP 442
Query: 614 VPSPG---------------SSSPQLQVKSSCKENPFNRKPSPAASPATKKATKGSKPVR 658
PSP S++P Q S P PSP ASP +
Sbjct: 443 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 502
Query: 659 PPAPGHGFPLIKRKVQA 675
PP L K QA
Sbjct: 503 PPLAAPPLQLAKPPPQA 519
Score = 36.6 bits (83), Expect = 0.10
Identities = 48/203 (23%), Positives = 63/203 (31%), Gaps = 44/203 (21%)
Query: 257 PSSSAPAGAEADGPKASPE--ARP--QIPTKPRVPGKLQELASPPAGRPTPAPR--KASE 310
PS+S P A P +P A P Q+P P LQ PP P + + +
Sbjct: 546 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL 605
Query: 311 STTPAPPTPRPRSSLQQENLVEQAGSSSLVNGRLHEL----------------------- 347
+ P PP P RS + + AG SS EL
Sbjct: 606 ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA 665
Query: 348 --PVPKPRGTPKPSEGTPAPRKDPPW------------ITLVQAEPKKKPAPLPPSSSPG 393
P RG P AP PW T+ + E + P P + PG
Sbjct: 666 CHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPG 725
Query: 394 P-PSQDSRQVENGGTEEVAQPSP 415
P P + G + SP
Sbjct: 726 PSPGTSGGKAAAGAGAGASSRSP 748
>gi|112382252 spectrin, beta, non-erythrocytic 1 isoform 2 [Homo
sapiens]
Length = 2155
Score = 108 bits (271), Expect = 2e-23
Identities = 60/149 (40%), Positives = 85/149 (57%), Gaps = 8/149 (5%)
Query: 5 RGALLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFENNR 64
+ ALL WC+ + GY V I + ++S+RDG+AF A++H+HRPDL+DFD L K N N +
Sbjct: 163 KDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQ 222
Query: 65 LAFEVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHFCSPGQAGVSPPRKGLAP 124
AF +AE+ LG+ LLDP D +S+ PD SI+TYV YY++F V R G
Sbjct: 223 NAFNLAEQHLGLTKLLDPED-ISVDHPDEKSIITYVVTYYHYFSKMKALAVEGKRIG--- 278
Query: 125 CSPPSVAPTPVEPEDVAQGEELSSGSLSE 153
V +E E + + E + L E
Sbjct: 279 ----KVLDNAIETEKMIEKYESLASDLLE 303
>gi|112382250 spectrin, beta, non-erythrocytic 1 isoform 1 [Homo
sapiens]
Length = 2364
Score = 108 bits (271), Expect = 2e-23
Identities = 60/149 (40%), Positives = 85/149 (57%), Gaps = 8/149 (5%)
Query: 5 RGALLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFENNR 64
+ ALL WC+ + GY V I + ++S+RDG+AF A++H+HRPDL+DFD L K N N +
Sbjct: 176 KDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQ 235
Query: 65 LAFEVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHFCSPGQAGVSPPRKGLAP 124
AF +AE+ LG+ LLDP D +S+ PD SI+TYV YY++F V R G
Sbjct: 236 NAFNLAEQHLGLTKLLDPED-ISVDHPDEKSIITYVVTYYHYFSKMKALAVEGKRIG--- 291
Query: 125 CSPPSVAPTPVEPEDVAQGEELSSGSLSE 153
V +E E + + E + L E
Sbjct: 292 ----KVLDNAIETEKMIEKYESLASDLLE 316
>gi|115430237 spectrin, beta, non-erythrocytic 4 isoform sigma1
[Homo sapiens]
Length = 2564
Score = 107 bits (268), Expect = 4e-23
Identities = 55/117 (47%), Positives = 75/117 (64%), Gaps = 1/117 (0%)
Query: 5 RGALLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFENNR 64
+ ALL WC+ + GY V I++ ++S+RDGLAF A++HRHRPDL+DF L+K N N +
Sbjct: 183 KDALLLWCQMKTAGYPEVNIQNFTTSWRDGLAFNALIHRHRPDLVDFSKLTKSNANYNLQ 242
Query: 65 LAFEVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHFCSPGQAGVSPPRKG 121
AF AE+ LG+ LLDP D V+M PD SI+TYV +Y++F V R G
Sbjct: 243 RAFRTAEQHLGLARLLDPED-VNMEAPDEKSIITYVVSFYHYFSKMKALAVEGKRIG 298
Score = 31.6 bits (70), Expect = 3.3
Identities = 32/132 (24%), Positives = 41/132 (31%), Gaps = 42/132 (31%)
Query: 275 EARPQIPTKPRVPGKLQELASPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQENLVEQA 334
EA P +P P +P Q PP P TP P PR R
Sbjct: 2334 EAGPGLPAGPSLP---QPRELPPGRLPNGLELP---ERTPRPDRPRARDR---------- 2377
Query: 335 GSSSLVNGRLHELPVPKPRGTPKPSEGTPAPRKDPPWITLVQAEPKKKPAPLPPSSSPGP 394
PKPR P+P EG + + AP S+P P
Sbjct: 2378 ---------------PKPRRRPRPREGGEG-----------GGSRRSRSAPAQGGSAPAP 2411
Query: 395 PSQDSRQVENGG 406
P + V++ G
Sbjct: 2412 PPPPTHTVQHEG 2423
>gi|12025678 actinin, alpha 4 [Homo sapiens]
Length = 911
Score = 106 bits (265), Expect = 8e-23
Identities = 66/179 (36%), Positives = 97/179 (54%), Gaps = 7/179 (3%)
Query: 8 LLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFENNRLAF 67
LL WC+R+ Y+ V +++ S++DGLAF A++HRHRP+L+++D L KD+ N AF
Sbjct: 169 LLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPELIEYDKLRKDDPVTNLNNAF 228
Query: 68 EVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHFCSPGQAGVSPPRKGLAPCSP 127
EVAEK L IP +LD D+V+ + PD +IMTYVS +Y+ F +A + R C
Sbjct: 229 EVAEKYLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAFSGAQKAETAANR----IC-- 282
Query: 128 PSVAPTPVEPEDVAQGEELSSGSLSEQGTGQTPSSTCAACQQHVHLVQRYLADGRLYHR 186
V E E + + E + L E P Q+ + +Q+ L D R Y R
Sbjct: 283 -KVLAVNQENEHLMEDYEKLASDLLEWIRRTIPWLEDRVPQKTIQEMQQKLEDFRDYRR 340
>gi|217330574 EH domain binding protein 1 isoform 3 [Homo sapiens]
Length = 1160
Score = 104 bits (260), Expect = 3e-22
Identities = 47/101 (46%), Positives = 74/101 (73%), Gaps = 1/101 (0%)
Query: 7 ALLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFENNRLA 66
+LL WC+ + YRGV+I + ++S+R+GL+FCAILH RPDL+D+ SL+ ++ ENN+ A
Sbjct: 413 SLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKA 472
Query: 67 FEVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHF 107
++ +GI LL+P+DMV +++PD L++MTY+ Q HF
Sbjct: 473 YD-GFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHF 512
Score = 93.2 bits (230), Expect = 9e-19
Identities = 85/318 (26%), Positives = 147/318 (46%), Gaps = 21/318 (6%)
Query: 519 ASQTAGAELLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQAS 578
A +G ++ E P+ + ++E G S + L E V+P+V P ++
Sbjct: 839 AEARSGVKMSELPSYGEMAAEKLKERSKASGEQNSKLVDLKLKKLLE-VQPQVANSPSSA 897
Query: 579 PGLAPRTRGSSGPQPAKPCSGATPTPLLLVGD---RSPVPSPGSSS---PQLQVKSSCKE 632
A + S Q K + T L R+PV S+ QLQ S E
Sbjct: 898 ---AQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIE 954
Query: 633 NPFNRKPSPAASPATKKATKGSKPVRPPA--PGHGFPLIKRKVQADQYIPEEDIHGEMDT 690
N K + TKK + + P L K QY+ GE+
Sbjct: 955 NRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVV-----GELAA 1009
Query: 691 IERRLDALEHRGVLLEEKLRGGLNEGR----EDDMLVDWFKLIHEKHLLVRRESELIYVF 746
+E ++ R L+E++LR ++ GR E+ M+ +WF L+++K+ L+RR ++L +
Sbjct: 1010 LENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLE 1069
Query: 747 KQQNLEQRQADVEYELRCLLNKPEKDWTEEDRAREKVLMQELVTLIEQRNAIINCLDEDR 806
K+ +LE+R + ELR +L + TE + RE++L+ ELV L+ +R+A++ LD
Sbjct: 1070 KEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQE 1129
Query: 807 QREEEEDKMLEAMIKKKE 824
++ EEED+ LE +++ +
Sbjct: 1130 KQAEEEDEHLERTLEQNK 1147
Score = 31.2 bits (69), Expect = 4.3
Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 18/97 (18%)
Query: 746 FKQQNLEQRQADVEYELRCLLNKPEKDWTEEDRAREKVLMQELVTLIEQRNAIINCLD-- 803
FK + + A +++ L C+ + K T+ED MQ L +L+ + A I LD
Sbjct: 138 FKPLSKKVVSAALQFSLSCIFLREGKA-TDED-------MQSLASLMSMKQADIGNLDDF 189
Query: 804 --------EDRQREEEEDKMLEAMIKKKEFQREAEPE 832
E+R +EE+ + +I K F EAE +
Sbjct: 190 EEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKD 226
>gi|217330572 EH domain binding protein 1 isoform 3 [Homo sapiens]
Length = 1160
Score = 104 bits (260), Expect = 3e-22
Identities = 47/101 (46%), Positives = 74/101 (73%), Gaps = 1/101 (0%)
Query: 7 ALLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFENNRLA 66
+LL WC+ + YRGV+I + ++S+R+GL+FCAILH RPDL+D+ SL+ ++ ENN+ A
Sbjct: 413 SLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKA 472
Query: 67 FEVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHF 107
++ +GI LL+P+DMV +++PD L++MTY+ Q HF
Sbjct: 473 YD-GFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHF 512
Score = 93.2 bits (230), Expect = 9e-19
Identities = 85/318 (26%), Positives = 147/318 (46%), Gaps = 21/318 (6%)
Query: 519 ASQTAGAELLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQAS 578
A +G ++ E P+ + ++E G S + L E V+P+V P ++
Sbjct: 839 AEARSGVKMSELPSYGEMAAEKLKERSKASGEQNSKLVDLKLKKLLE-VQPQVANSPSSA 897
Query: 579 PGLAPRTRGSSGPQPAKPCSGATPTPLLLVGD---RSPVPSPGSSS---PQLQVKSSCKE 632
A + S Q K + T L R+PV S+ QLQ S E
Sbjct: 898 ---AQKAVTESSEQDMKSGTEDLRTERLQKTTERFRNPVVFSKDSTVRKTQLQSFSQYIE 954
Query: 633 NPFNRKPSPAASPATKKATKGSKPVRPPA--PGHGFPLIKRKVQADQYIPEEDIHGEMDT 690
N K + TKK + + P L K QY+ GE+
Sbjct: 955 NRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVV-----GELAA 1009
Query: 691 IERRLDALEHRGVLLEEKLRGGLNEGR----EDDMLVDWFKLIHEKHLLVRRESELIYVF 746
+E ++ R L+E++LR ++ GR E+ M+ +WF L+++K+ L+RR ++L +
Sbjct: 1010 LENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALIRRMNQLSLLE 1069
Query: 747 KQQNLEQRQADVEYELRCLLNKPEKDWTEEDRAREKVLMQELVTLIEQRNAIINCLDEDR 806
K+ +LE+R + ELR +L + TE + RE++L+ ELV L+ +R+A++ LD
Sbjct: 1070 KEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRDALVRDLDAQE 1129
Query: 807 QREEEEDKMLEAMIKKKE 824
++ EEED+ LE +++ +
Sbjct: 1130 KQAEEEDEHLERTLEQNK 1147
Score = 31.2 bits (69), Expect = 4.3
Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 18/97 (18%)
Query: 746 FKQQNLEQRQADVEYELRCLLNKPEKDWTEEDRAREKVLMQELVTLIEQRNAIINCLD-- 803
FK + + A +++ L C+ + K T+ED MQ L +L+ + A I LD
Sbjct: 138 FKPLSKKVVSAALQFSLSCIFLREGKA-TDED-------MQSLASLMSMKQADIGNLDDF 189
Query: 804 --------EDRQREEEEDKMLEAMIKKKEFQREAEPE 832
E+R +EE+ + +I K F EAE +
Sbjct: 190 EEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKD 226
>gi|217330570 EH domain binding protein 1 isoform 2 [Homo sapiens]
Length = 1196
Score = 104 bits (260), Expect = 3e-22
Identities = 47/101 (46%), Positives = 74/101 (73%), Gaps = 1/101 (0%)
Query: 7 ALLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFENNRLA 66
+LL WC+ + YRGV+I + ++S+R+GL+FCAILH RPDL+D+ SL+ ++ ENN+ A
Sbjct: 413 SLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKA 472
Query: 67 FEVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHF 107
++ +GI LL+P+DMV +++PD L++MTY+ Q HF
Sbjct: 473 YD-GFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHF 512
Score = 92.0 bits (227), Expect = 2e-18
Identities = 62/208 (29%), Positives = 108/208 (51%), Gaps = 11/208 (5%)
Query: 623 QLQVKSSCKENPFNRKPSPAASPATKKATKGSKPVRPPA--PGHGFPLIKRKVQADQYIP 680
QLQ S EN K + TKK + + P L K QY+
Sbjct: 981 QLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVV 1040
Query: 681 EEDIHGEMDTIERRLDALEHRGVLLEEKLRGGLNEGR----EDDMLVDWFKLIHEKHLLV 736
GE+ +E ++ R L+E++LR ++ GR E+ M+ +WF L+++K+ L+
Sbjct: 1041 -----GELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALI 1095
Query: 737 RRESELIYVFKQQNLEQRQADVEYELRCLLNKPEKDWTEEDRAREKVLMQELVTLIEQRN 796
RR ++L + K+ +LE+R + ELR +L + TE + RE++L+ ELV L+ +R+
Sbjct: 1096 RRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRD 1155
Query: 797 AIINCLDEDRQREEEEDKMLEAMIKKKE 824
A++ LD ++ EEED+ LE +++ +
Sbjct: 1156 ALVRDLDAQEKQAEEEDEHLERTLEQNK 1183
Score = 31.2 bits (69), Expect = 4.3
Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 18/97 (18%)
Query: 746 FKQQNLEQRQADVEYELRCLLNKPEKDWTEEDRAREKVLMQELVTLIEQRNAIINCLD-- 803
FK + + A +++ L C+ + K T+ED MQ L +L+ + A I LD
Sbjct: 138 FKPLSKKVVSAALQFSLSCIFLREGKA-TDED-------MQSLASLMSMKQADIGNLDDF 189
Query: 804 --------EDRQREEEEDKMLEAMIKKKEFQREAEPE 832
E+R +EE+ + +I K F EAE +
Sbjct: 190 EEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKD 226
>gi|217330568 EH domain binding protein 1 isoform 1 [Homo sapiens]
Length = 1231
Score = 104 bits (260), Expect = 3e-22
Identities = 47/101 (46%), Positives = 74/101 (73%), Gaps = 1/101 (0%)
Query: 7 ALLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFENNRLA 66
+LL WC+ + YRGV+I + ++S+R+GL+FCAILH RPDL+D+ SL+ ++ ENN+ A
Sbjct: 448 SLLVWCKEVTKNYRGVKITNFTTSWRNGLSFCAILHHFRPDLIDYKSLNPQDIKENNKKA 507
Query: 67 FEVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHF 107
++ +GI LL+P+DMV +++PD L++MTY+ Q HF
Sbjct: 508 YD-GFASIGISRLLEPSDMVLLAIPDKLTVMTYLYQIRAHF 547
Score = 92.0 bits (227), Expect = 2e-18
Identities = 62/208 (29%), Positives = 108/208 (51%), Gaps = 11/208 (5%)
Query: 623 QLQVKSSCKENPFNRKPSPAASPATKKATKGSKPVRPPA--PGHGFPLIKRKVQADQYIP 680
QLQ S EN K + TKK + + P L K QY+
Sbjct: 1016 QLQSFSQYIENRPEMKRQRSIQEDTKKGNEEKAAITETQRKPSEDEVLNKGFKDTSQYVV 1075
Query: 681 EEDIHGEMDTIERRLDALEHRGVLLEEKLRGGLNEGR----EDDMLVDWFKLIHEKHLLV 736
GE+ +E ++ R L+E++LR ++ GR E+ M+ +WF L+++K+ L+
Sbjct: 1076 -----GELAALENEQKQIDTRAALVEKRLRYLMDTGRNTEEEEAMMQEWFMLVNKKNALI 1130
Query: 737 RRESELIYVFKQQNLEQRQADVEYELRCLLNKPEKDWTEEDRAREKVLMQELVTLIEQRN 796
RR ++L + K+ +LE+R + ELR +L + TE + RE++L+ ELV L+ +R+
Sbjct: 1131 RRMNQLSLLEKEHDLERRYELLNRELRAMLAIEDWQKTEAQKRREQLLLDELVALVNKRD 1190
Query: 797 AIINCLDEDRQREEEEDKMLEAMIKKKE 824
A++ LD ++ EEED+ LE +++ +
Sbjct: 1191 ALVRDLDAQEKQAEEEDEHLERTLEQNK 1218
>gi|67782321 spectrin beta isoform a [Homo sapiens]
Length = 2328
Score = 103 bits (258), Expect = 5e-22
Identities = 53/117 (45%), Positives = 74/117 (63%), Gaps = 1/117 (0%)
Query: 5 RGALLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFENNR 64
+ ALL WC+ + GY V + + +SS++DGLAF A++H+HRPDL+DFD L N N
Sbjct: 176 KDALLLWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKLKDSNARHNLE 235
Query: 65 LAFEVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHFCSPGQAGVSPPRKG 121
AF VAE++LGI LLDP D+ + + PD SI+TYV +Y++F V R G
Sbjct: 236 HAFNVAERQLGIIPLLDPEDVFTEN-PDEKSIITYVVAFYHYFSKMKVLAVEGKRVG 291
>gi|67782319 spectrin beta isoform b [Homo sapiens]
Length = 2137
Score = 103 bits (258), Expect = 5e-22
Identities = 53/117 (45%), Positives = 74/117 (63%), Gaps = 1/117 (0%)
Query: 5 RGALLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFENNR 64
+ ALL WC+ + GY V + + +SS++DGLAF A++H+HRPDL+DFD L N N
Sbjct: 176 KDALLLWCQMKTAGYPHVNVTNFTSSWKDGLAFNALIHKHRPDLIDFDKLKDSNARHNLE 235
Query: 65 LAFEVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHFCSPGQAGVSPPRKG 121
AF VAE++LGI LLDP D+ + + PD SI+TYV +Y++F V R G
Sbjct: 236 HAFNVAERQLGIIPLLDPEDVFTEN-PDEKSIITYVVAFYHYFSKMKVLAVEGKRVG 291
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 100 bits (249), Expect = 6e-21
Identities = 123/452 (27%), Positives = 169/452 (37%), Gaps = 71/452 (15%)
Query: 253 PGGGPSSSAPAGAEADGPKA---SPEARPQIPTKPRVPGKLQELASPPAGRPTPAPRKAS 309
P GGP++ +P GA P A SP+ P P+ P P G P P
Sbjct: 973 PKGGPATPSPKGAPTP-PAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKG 1031
Query: 310 ESTTPAPPTPRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKP-------RGTPKPSEGT 362
ST PA P P+ S L + A ++ LP PK +G P P T
Sbjct: 1032 ASTPPAATPPSPKGSPAATPLPKGAPTTPAAT-----LPSPKGGPATPSLKGAPTPPAAT 1086
Query: 363 PAPRKDPPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGG---TEEVAQPSPTASL 419
P K P A P K AP+PP+++P P + G T PSP L
Sbjct: 1087 PPSPKGGP------ATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGL 1140
Query: 420 ESKPYNPFEEEEEDKEEEAPAAPS--LATSPALGHPESTPKSLHPW-YGITPTSSPKTKK 476
+ P + P +P LAT P G P +TP + P G T SPK
Sbjct: 1141 ATPP----PKGAPTTPAATPPSPKGGLATPPPKGAP-TTPAATPPSPKGGLATPSPKG-- 1193
Query: 477 RPAPRAPSASP------LALHASRLSHSEPPSATPSPALSVESLSSESASQTAGAELLEP 530
AP P+A+P LA + + + + P + PSP + + S + A T A P
Sbjct: 1194 --APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP 1251
Query: 531 ---PAVPKSSSEPAVHAPGTPGNPVSLST--NSSLASSGELVEPRVEQMPQASP------ 579
PA P P A P L+T + + + P + P SP
Sbjct: 1252 KGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPT 1311
Query: 580 ---GLAPRTRGSSGPQPAKPCSGATPTPLLLVGDRSPVPSPGSSSPQLQ---VKSSCKEN 633
P +GS G P K GA P + P+ +++P + S KE
Sbjct: 1312 PPAATPPSPKGSPGTPPPK---GAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEG 1368
Query: 634 PFNRKPSPAASPATKKATKGSKPVRPPAPGHG 665
P PAA+P+ K G + PP+P G
Sbjct: 1369 P----TPPAATPSHK----GGPAMTPPSPKRG 1392
Score = 99.0 bits (245), Expect = 2e-20
Identities = 122/481 (25%), Positives = 177/481 (36%), Gaps = 64/481 (13%)
Query: 200 PGAYENGPEEGTFVCAEHCARLGPGTRSGTRPGPFSQPKQQHQQQLAEDAKDVPGGGPSS 259
P A P+ G + A + P + G + P + P GG ++
Sbjct: 1083 PAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLAT 1142
Query: 260 SAPAGAEADGPKASPEARPQIPTKPRVPGKLQELASPPA---GRPTPAPRKASESTTPAP 316
P GA P + + T P A+PP+ G TP+P+ A TTPA
Sbjct: 1143 PPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGA--PTTPAA 1200
Query: 317 PTPRPRSSLQQENLVEQAGSSSLVNGRLHELPVPK-----PRGTPKPSEG---TPAPRKD 368
P P+ L P PK P TP +G TP+P+
Sbjct: 1201 TPPSPKGGL--------------------ATPSPKGAPTTPAATPPSPKGGLATPSPKGA 1240
Query: 369 PPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQPSPTASLESKPYNPFE 428
P PK PA PP +P PP+ ++ G + +P ++ + P +P
Sbjct: 1241 PTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPP-SPKG 1299
Query: 429 EEEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPTSSPKTKKRPAPRAPSASPL 488
+ AP P+ AT P+ P+ +P + P TP + + P P+ +P
Sbjct: 1300 GPATSPPKGAPTPPA-ATPPS---PKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPS 1355
Query: 489 ALHASRLSHSE----PPSATPS----PALSVESLSSESASQTAGAELLEPPAVPKSSSEP 540
+ S+ PP+ATPS PA++ S A + + P +P S +
Sbjct: 1356 SKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKK- 1414
Query: 541 AVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAPRTRGSSGPQPAKPCSGA 600
AP TP +T S G+L P V + S AP T G PA P S
Sbjct: 1415 ---APATPVTREGAAT----PSKGDLTPPAVTPV---SLKKAPATSAPKG-GPATPSSKG 1463
Query: 601 TPTPLLLVGDRSPVPSPGSSSPQLQVKSSCKENPFNRKPSPAASPATKKATKGSKPVRPP 660
PT L P P + Q+ SS K+ P P+P +P T A S P P
Sbjct: 1464 DPT---LPAVTPPSPKEPPAPKQVATSSSPKKAP--ATPAPMGAP-TLPAVIPSSPKEVP 1517
Query: 661 A 661
A
Sbjct: 1518 A 1518
Score = 96.7 bits (239), Expect = 8e-20
Identities = 119/461 (25%), Positives = 163/461 (35%), Gaps = 58/461 (12%)
Query: 223 PGTRSGTRPGP---FSQPKQQHQQQLAEDAKDVPGGGPSSSAPAGAEADGPKASPEARPQ 279
P T + T P P + P + P GGP++ P GA P +
Sbjct: 1218 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGG 1277
Query: 280 IPTKPRVPGKLQELASPPA--GRPTPAPRKASESTTPAPPTPRPRSSLQQENLVEQAGSS 337
+ T P + +PP+ G P +P K + T PA P P+ S
Sbjct: 1278 LATPPHKGAPNPAVVTPPSPKGGPATSPPKGA-PTPPAATPPSPKGS------------- 1323
Query: 338 SLVNGRLHELPVPKPRGTPKPSEGTPAPRKDPPWITLVQAEPKKKPAPLPPSSSPGPPSQ 397
P P+G P P TP K P TL P K P PSS GP
Sbjct: 1324 ---------PGTPPPKGAPTPPAVTPPSPKGTP--TLPATTPSSKGGPTTPSSKEGPTPP 1372
Query: 398 DSRQVENGGTEEVAQPSPTASLESKPYNPFEEEEEDKEEEAPAAPSLA-TSPALGHPEST 456
+ GG + PSP + P P + + P +P A +P +T
Sbjct: 1373 AATPSHKGG-PAMTPPSP----KRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAAT 1427
Query: 457 PK--SLHPWYGITPTSSPKTKKRPAPRAPSASPLALHASRLSHSEPPSATPSPA-LSVES 513
P L P +TP S K AP+ A+P + L PPS PA V +
Sbjct: 1428 PSKGDLTP-PAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVAT 1486
Query: 514 LSSESASQTAGAELLEP--PAVPKSSSEPAVHAPGTPGNPV-------SLSTNSSLASSG 564
SS + A + P PAV SS + P + +P+ S T ++LA
Sbjct: 1487 SSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKE 1546
Query: 565 ELVEPRVE-QMPQASPGLAPRTRGSSGPQPAKPCSGATPTPLLLVGDRSP---VPSPGSS 620
L+ P + P+ +P + + P + S TP G SP + P +
Sbjct: 1547 ALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVT 1606
Query: 621 SPQLQVKSSCKENPFNRKPSPAASPAT--KKATKGSKPVRP 659
SP P PSP PAT K T S PV P
Sbjct: 1607 SPS---PKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTP 1644
Score = 94.7 bits (234), Expect = 3e-19
Identities = 118/475 (24%), Positives = 163/475 (34%), Gaps = 40/475 (8%)
Query: 200 PGAYENGPEEGTFVCAEHCARLGPGTRSGTRPGPFSQPKQQHQQQLAEDAKDVPGGGPSS 259
P A P+ G A P + G + P + A P GGP++
Sbjct: 1244 PAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPAT 1303
Query: 260 SAPAGAEADGPKASPEARPQIPTKPRVPGKLQELASPPAGRPT-PAPRKASESTTPAPPT 318
S P GA P A+P + P P PP G PT PA S TP P
Sbjct: 1304 SPPKGAPTP-PAATPPSPKGSPGTP-----------PPKGAPTPPAVTPPSPKGTPTLPA 1351
Query: 319 PRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKPRGTPKPSEGTPAPRKDPPWITLVQAE 378
P S + G + H+ +PK P+P+ DP ++
Sbjct: 1352 TTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLS 1411
Query: 379 PKKKP--------APLPPSSSPGPPSQDSRQVENGGTEEVAQPSP-TASLESKPYNPFEE 429
PKK P A P PP+ ++ + P T S + P P
Sbjct: 1412 PKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVT 1471
Query: 430 EEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPTSSPKTKKRPAPRAPSASPLA 489
KE AP + ++SP P + P+S K+ PA + P+A
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSS---PKEVPATPSSRRDPIA 1528
Query: 490 LHASRLSHSEPPSATPSPALSVESLSSESASQTAGAELLEPPAVPKSSSEPAVHAPGTPG 549
A+ LS P + P AL +++ S +T PA+P PA +
Sbjct: 1529 PTATLLSKKTPATLAPKEALIPPAMTVPSPKKT--------PAIPTPKEAPATPSSKEAS 1580
Query: 550 NP--VSLSTNSSLASSGELVEPRVEQMPQASPGLAPRTRGSSGPQPAKPCSGATPTPLLL 607
+P V+ ST S EL+ P P SP AP + P P K ATP P
Sbjct: 1581 SPPAVTPSTYKGAPSPKELLIPPAVTSP--SPKEAPTPPAVTPPSPEK--GPATPAPKGT 1636
Query: 608 VGDRSPVPSPGSSSPQLQVKSSCKENPFNRKPSPAASPATKKATKGSKPVRPPAP 662
PS SP +CK + S PA K T + + PAP
Sbjct: 1637 PTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGL-PAKKGPTALKEVLVAPAP 1690
Score = 83.2 bits (204), Expect = 1e-15
Identities = 132/542 (24%), Positives = 180/542 (33%), Gaps = 115/542 (21%)
Query: 222 GPGTRSGTRPGPFSQPKQQHQQQLA---EDAKDVPGGGPSSSAPAGAEADGPKASPEARP 278
GP T G P S + + + + +KD P S + P+ A P A P
Sbjct: 816 GPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSP 875
Query: 279 Q---IPTKPRVPGKLQELASPPAGRPTPAPRKA------SESTTPAPPTPRPRSSLQQEN 329
+ +P K + L P G TPAP++A S S A TP P+
Sbjct: 876 KGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGI----- 930
Query: 330 LVEQAGSSSLVNGRLHELPVPKPRG---TPKPSEGTPAPRKDPPWITLVQAEPKKKPAPL 386
A S P P+G TP P P PP A P K AP
Sbjct: 931 ---PASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPT 987
Query: 387 PPSSSPGPPSQDSRQVENGGT---EEVAQPSPTASLESKPY------NPFEEEEEDKEEE 437
PP+++P P G V PSP S + P+ P K
Sbjct: 988 PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSP 1047
Query: 438 A----------------------PAAPSLATSPALGHPESTPKSLHPWYG---------- 465
A PA PSL +P P +TP S P G
Sbjct: 1048 AATPLPKGAPTTPAATLPSPKGGPATPSLKGAPT--PPAATPPS--PKGGPATPSPKGAP 1103
Query: 466 ITPTSSPKTKK--------RPAPRAPSASP------LALHASRLSHSEPPSATPSPALSV 511
+ P ++P + K + AP P+A+P LA + + + P + PSP +
Sbjct: 1104 MPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL 1163
Query: 512 ESLSSESASQTAGAELLEPP---AVPKSSSEPAVHAPGTPGNPVSLSTNSSLAS------ 562
+ + A T A P A P P A P L+T S +
Sbjct: 1164 ATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1223
Query: 563 -----SGELVEPRVEQMPQASPGLAPRTRGSSGPQPAKPCSGATP---TPLLLVGDRSPV 614
G L P + P P +G GP P TP TP L G +
Sbjct: 1224 TPPSPKGGLATPSPKGAPTTPAATPPSPKG--GPATPPPKGAPTPPAATPPSLKGGLATP 1281
Query: 615 PSPGSSSPQLQVKSSCKENPFNRKPS-----PAASPATKKATKGSKP---------VRPP 660
P G+ +P + S K P P PAA+P + K + G+ P V PP
Sbjct: 1282 PHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPP 1341
Query: 661 AP 662
+P
Sbjct: 1342 SP 1343
Score = 62.0 bits (149), Expect = 2e-09
Identities = 125/507 (24%), Positives = 178/507 (35%), Gaps = 103/507 (20%)
Query: 224 GTRSGTRPGPFSQPKQQHQQQLAEDAKDVPGGGPSSSAPAGAEADGPKASPEARPQIPTK 283
G T P P S QQ A A P PS+ A E P++S + T
Sbjct: 39 GQPGPTLPPPCSPAPQQCPLSAANQASPFPS--PSTIASTPLEVPFPQSSSGTALPLGTA 96
Query: 284 PRVPGKLQELASPP-------AGRPTPAPRKASESTTPAP-------PTPRPRSSLQQEN 329
P P L L PP P AP ++ AP P +SS N
Sbjct: 97 PEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPN 156
Query: 330 LVEQAGSSSLV-NGRLHELPVPKPRGTPK------PSEGTPAPRKDPPWITLVQAEPKKK 382
L+ S ++ +G + L P PK PSE P P+ P +V P
Sbjct: 157 LLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHC 216
Query: 383 PAPLPPSSSPGPPSQDSRQVENGGTEEVAQPSPTASLESKPYNPFEEEEEDKEEEAPAAP 442
P+ S G + Q +PT +L + ++ +P
Sbjct: 217 VTPMASIQS--------------GVASLPQTTPTTTLAIAS----PQVKDTTISSVLISP 258
Query: 443 SLATSPALGHPESTPKSLHPWYGITP--TSSPKTKKRPAPRAPSASPLAL--HASRLSHS 498
S +L P S P +L P TSS KT P P P++L H + L S
Sbjct: 259 QNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKT---AGPNTPPDFPISLGSHLAPLHQS 315
Query: 499 E----------PPSATPSPALSVESL--SSESASQTAGAELLEP-----PAVPKSSSEPA 541
PSA P + S+ SS AS + ++ P VP + +
Sbjct: 316 SFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFP 375
Query: 542 VHAPG-------------TPGNPVSLSTNSSLASSGELV----------EPRVEQMPQAS 578
V AP +P ++++T+ SL+ + L+ P V QMP +S
Sbjct: 376 VVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSS 435
Query: 579 PGLAPRTRGSSGPQPAKPCS-GATPTPLLLVGDRSPVPSPGSSSPQLQVKSSCKENPFNR 637
G P PC+ A PT V + V P SS P ++ + +P
Sbjct: 436 VGTTPLV-------VTNPCTIAAAPTTTFEVA--TCVSPPMSSGPISNIEPT---SPAAL 483
Query: 638 KPSPAA--SPATKKATKGSKPVRPPAP 662
+P A P+T+ AT PV PP P
Sbjct: 484 VMAPVAPKEPSTQVATTLRIPVSPPLP 510
Score = 53.5 bits (127), Expect = 8e-07
Identities = 86/352 (24%), Positives = 131/352 (37%), Gaps = 35/352 (9%)
Query: 237 PKQQHQQQLAEDAKDVPGGGPSS--SAPAGAEADGPKASPEARP-QIPTKPRV--PGKLQ 291
PK+ +++A P PS+ AP+ E P A P + PT P V P +
Sbjct: 1567 PKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEK 1626
Query: 292 ELASP-PAGRPTPAPRKASE----STTPAPPTPRPRSSLQQ--ENLVEQAGSSSLVNGRL 344
A+P P G PT P S T+PA T + +++ Q + L + G ++L
Sbjct: 1627 GPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKE--- 1683
Query: 345 HELPVPKPRGTP---KPSEGTPAPRKDPPWITLVQAEPKKKPAPLPPSSSPGPP-----S 396
L P P TP P+ P +K + +P K P S+ P
Sbjct: 1684 -VLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQ 1742
Query: 397 QDSRQVENGGTEEVAQPSPTASLESKPYNPFEEEEEDKEEEAPAAPSLATSPALGHPEST 456
+DS + G + P A ESK P +K P + S++ +P+ P S
Sbjct: 1743 KDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPS--PPVSL 1800
Query: 457 PKSLHPWYGITPTSSPKTKKRPAPRAPSASPLALHASRLSHSEPPSATPSPALSVESLSS 516
P + P PT PK + PS+ L L + + P + E +S
Sbjct: 1801 PLAPSP----VPTLPPKQQ-----FLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISG 1851
Query: 517 ESASQTAGAELLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVE 568
Q+ + P + P+ P T N S + + S S EL E
Sbjct: 1852 GVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEE 1903
Score = 52.4 bits (124), Expect = 2e-06
Identities = 104/421 (24%), Positives = 145/421 (34%), Gaps = 47/421 (11%)
Query: 281 PTKPRVPGKLQELASPPAGRPTPAPRKASESTTP-APPTPRPRSSLQQENLVEQAGSSSL 339
PT P L P P+ + A+ P +PP P P +NL
Sbjct: 477 PTSPAA------LVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDL---KNLPSSVLVKFP 527
Query: 340 VNGRLHELPVPKPRGTPKPSEGTPAPRKDPPWITLVQAEPKKKPAPLPPSSSPGPPSQDS 399
L +P P++ +KDP + LVQA PK P+ SSSP P
Sbjct: 528 TQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPE 587
Query: 400 RQVENGGTEEVAQPSPTASLESKPYNPFEEEEEDK--EEEAPAAPSLATSPALGHPESTP 457
+ + + +P P S +P + ++ A P A P L TP
Sbjct: 588 ATL---AKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSA-GPLLKSSLITP 643
Query: 458 K-SLHPWYGITPTS-SPKTKKRPAPRAPSASPLALHASRLSHSEPP----SATPSPALSV 511
+ P P +P T K + +ASP L+ P + T P +
Sbjct: 644 TVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPT 703
Query: 512 ESLSSESASQTAG-----AELLEPPAVPKSSSEPAVHAPGTPGNPV---SLSTNSSLASS 563
S + A A L+ P +PKS P++ GTP +S S+LA
Sbjct: 704 ASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAP- 762
Query: 564 GELVEPRVEQMPQASPGLAPRTRGSSG--------PQP-AKPCSGATPTPLLLVGDRSP- 613
V ++ P G A T S G P P S T P G P
Sbjct: 763 ---VASSPKECPTEDSG-ASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPD 818
Query: 614 VPSPGSSSPQLQVKSS-CKENPFNRKPSPAASPATKKATKGSKPVRPPAPGHGFPLIKRK 672
P SSP V++S EN + + S SPAT + P P P PL +
Sbjct: 819 TPIGNLSSPVSPVEASFLPENSLSFQGS-KDSPATTHSPTPPSPKGAPTPSAVTPLSPKG 877
Query: 673 V 673
V
Sbjct: 878 V 878
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 100 bits (248), Expect = 8e-21
Identities = 137/478 (28%), Positives = 176/478 (36%), Gaps = 93/478 (19%)
Query: 219 ARLGPGTRSGTR-PGPFSQPKQQHQQ-----QLAEDAKDV-PGGGPSSSAPAGAEADGPK 271
AR GP R R P SQPK + Q Q+ KD P GP SS+P +
Sbjct: 244 ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAP 303
Query: 272 ASPEARPQIPTKPRVPGKLQELASPPAGRPTPAPRKASESTTPAPP-----TPRPRSSLQ 326
SP A P + T P P A+ G PT +A+ S P+PP TP P++
Sbjct: 304 PSPSAPPSLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPA 360
Query: 327 QENLVEQAGSSSLVNGRLHELPVPKPRG-------------TPKPSEGTPAPRKDPPWIT 373
QA S + L L P P+ +P PS AP P
Sbjct: 361 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP---- 416
Query: 374 LVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQPSPTASLESKPYNPFEEEEED 433
A P P+ PPS +P + QV PSP AS P
Sbjct: 417 ---ASPPVSPSATPPSQAPPSLAAPPLQV---------PPSPPASPPMSP---------S 455
Query: 434 KEEEAPAAPSLATSP---ALGHPESTPKSLHPWYGITPTSSPKTKKRPAPRAPSAS-PLA 489
A P LA P A P++ P P P S P + AP +PSAS P++
Sbjct: 456 ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP-SPPASFPGQAPFSPSASLPMS 514
Query: 490 LHASRLSHSEPPSATPSPALSVESLSSESASQTAGAELLE-PPAVPKSSSEPAVHAPGTP 548
P ATP P A A LL+ PP+ P S + A P TP
Sbjct: 515 -----------PLATPPP----------QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 553
Query: 549 GNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAPRTRGSSGPQPAKPCSGATPTPLLLV 608
G S+ SG + + P P +P + SGP A S AT TP L
Sbjct: 554 GPDTSV--------SGPRLTLALAPGPPPPPSRSPSST-LSGPDLAGHSSSATSTPEELR 604
Query: 609 G-DRSPVPSPGSSSPQLQVKSSCKENPFNRKPSPAASPATKKATKGSKPVRPPAPGHG 665
G D P +S P ++C ++R P+P P + G+ PPA G G
Sbjct: 605 GYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP---PLAFRGAPGAPLPWPPATGPG 659
Score = 97.1 bits (240), Expect = 6e-20
Identities = 136/492 (27%), Positives = 190/492 (38%), Gaps = 96/492 (19%)
Query: 223 PGTRSGT-RPGPFSQP----------------KQQHQQQLAEDAK-DVPGGGPSSSAPA- 263
PG SGT RPGP Q + + L+ A+ D G P + +PA
Sbjct: 108 PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM 167
Query: 264 -------GAEADGPKASPEARPQIPTKPRVPGKLQELASPPAG-RPTPAPRK--ASESTT 313
G E P+ +P ARP+ PT+ P K AS + P+PA R+ ++
Sbjct: 168 ARRSRAAGTEVGLPRPAPSARPRPPTEG--PRKSVSSASEHSTTEPSPAARRRPSAGGGL 225
Query: 314 PAPPTPRPRSSLQQENLVEQAGSSSLVNGRLHELPV-PKPRGTP--KPSEGTPAPRKDP- 369
P + SS + ++G S+ R P PKP+G +P + TP PRKD
Sbjct: 226 QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP-PRKDAA 284
Query: 370 PWITLVQAEPKKKPAPLPPSSSPGPPSQDS-----RQVENGGTEEVAQPSPTAS---LES 421
P + + + P P+P P S PPS + + T + P+ A+ L S
Sbjct: 285 PALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPS 344
Query: 422 KPYNPFEEEEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPTSSPKTKKRPAPR 481
P +P P AP P L P S P S P SP P+P+
Sbjct: 345 PPLSPLATPP-------PQAPPALALPPLQAPPSPPAS--------PPLSPLAT--PSPQ 387
Query: 482 APSASPLALHASRLSHSEPPSATPSPALSVESLSSESASQTAGAELLEPPAVPKSSSEPA 541
AP+A LA+H + S PPS V++ S AS P P S + P
Sbjct: 388 APNA--LAVHLLQAPFSPPPSPP------VQAPFSPPASPPVSPSATPPSQAPPSLAAPP 439
Query: 542 VHAPGTP--GNPVSLSTNSSLASSGELVEPRVEQM---PQASPGLAPRTRGSSGPQPAK- 595
+ P +P P+S S + L P ++ PQA P LA + PA
Sbjct: 440 LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASF 499
Query: 596 ----PCSGATPTPLLLVGDRSPVPSPGSSSPQLQVKSSCKENPFNRKPSPAASPATKKAT 651
P S + P+ + P P ++P LQV PSP ASP +
Sbjct: 500 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV-----------PPSPPASPTLQ--- 545
Query: 652 KGSKPVRPPAPG 663
P RPP PG
Sbjct: 546 ---APRRPPTPG 554
Score = 91.7 bits (226), Expect = 3e-18
Identities = 126/450 (28%), Positives = 176/450 (39%), Gaps = 84/450 (18%)
Query: 270 PKASPEARPQIPTKPRVPGKLQELASPPAGRPTP----APRKASESTTPAPPTPRPRSSL 325
P+++P A P ++P G+ + +PPA +P +P +AS +T P P L
Sbjct: 71 PESAPRAGPTRTSRPPASGRGER--APPAKNTSPGPVSSPGRASGTTRPGP--------L 120
Query: 326 QQENLVEQAGSSSLVNGRLHELPVPKP------RGTPKPSEGTPAPRKDPPWITLVQAEP 379
Q+ L A ++ G+ E P R T P+ GTP+P +A
Sbjct: 121 GQKGLRISA-EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM----ARRSRAAG 175
Query: 380 KKKPAPLP-PSSSPGPPSQDSRQ-VENGGTEEVAQPSPTASLESKPYNPFEEEEEDKEEE 437
+ P P PS+ P PP++ R+ V + +PSP A +
Sbjct: 176 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR-------- 227
Query: 438 APAAPSLATSPALGHPESTPKSLHPWYGITPT-----SSPKTKKRPAPRAPSASPLALHA 492
PA+ SL++S P S+P P TP S PK K A R P +P A
Sbjct: 228 -PASRSLSSSAT---PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA 283
Query: 493 SRLSH--SEPPSATPSPALSVESLSSESASQTAGAELLEPPAVPKSSSEPAVHAPGTPGN 550
+ S P ATPSP+ + S S+ + QT L PPA P S + ++ G+
Sbjct: 284 APALGPLSSSPLATPSPS-APPSPSAPPSLQT----LPSPPATPPSQATTSL------GS 332
Query: 551 PVSLSTNSSLASSGELVEPRVEQMPQASPGLA-PRTRGSSGPQPAKPCSG-ATPTPL--- 605
P +T+S L S + P PQA P LA P + P + P S ATP+P
Sbjct: 333 PTLQATHSFLPSPP--LSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPN 390
Query: 606 -----LLVGDRSPVPSPG---------------SSSPQLQVKSSCKENPFNRKPSPAASP 645
LL SP PSP S++P Q S P PSP ASP
Sbjct: 391 ALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP 450
Query: 646 ATKKATKGSKPVRPPAPGHGFPLIKRKVQA 675
+ PP L K QA
Sbjct: 451 PMSPSATPPPQAPPPLAAPPLQLAKPPPQA 480
Score = 52.8 bits (125), Expect = 1e-06
Identities = 78/326 (23%), Positives = 111/326 (34%), Gaps = 53/326 (16%)
Query: 347 LPVPKPRGTPKPSEGTPAPRKDPPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGG 406
L P+P G+P+P PP +T PA L + G + GG
Sbjct: 24 LLTPRPPGSPRP----------PPPVT---------PAALRVLGAAGAVGRKPLAERAGG 64
Query: 407 TEEVAQPSPTASLESKPYNPFEEEEEDKEEEAPAA----PSLATSPALGHPESTPKSLHP 462
P ++ + P + E AP A P +SP + P L
Sbjct: 65 IGGATIPE--SAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQ 122
Query: 463 WYGITPTSSPKTKKRPAPRAPSASPLALHASRLSHSEPPSATPSPALSVESLSSESASQT 522
G+ ++ + A AP S L+ A R S P TPSPA++ S+
Sbjct: 123 -KGLRISAEETVARGKATEAPKRSALSAGARR-DTSGPTPGTPSPAMA-------RRSRA 173
Query: 523 AGAELLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASPGL- 581
AG E+ P P + P P S +S+ S P + P A GL
Sbjct: 174 AGTEVGLPRPAPSARPRPPTEGPRK-------SVSSASEHSTTEPSPAARRRPSAGGGLQ 226
Query: 582 --APRTRGSSGP---QPAKPCSGATPTPLLLVGDRSPVPSPGSSSPQLQVKSSCKENPFN 636
A R+ SS PA+ A TP R+P LQ + P
Sbjct: 227 RPASRSLSSSATPLSSPARSGPSARGTP------RAPAHPSQPKPKGLQALRPPQVTPPR 280
Query: 637 RKPSPAASPATKKATKGSKPVRPPAP 662
+ +PA P + P PP+P
Sbjct: 281 KDAAPALGPLSSSPLATPSPSAPPSP 306
>gi|118918413 MICAL C-terminal like [Homo sapiens]
Length = 695
Score = 97.8 bits (242), Expect = 4e-20
Identities = 126/520 (24%), Positives = 218/520 (41%), Gaps = 73/520 (14%)
Query: 332 EQAGSSSLVNGR-------LHELPVPKPRGTPKPSE-------GTPA----------PRK 367
E+ S NGR + L +P+ G P P++ GTPA P K
Sbjct: 208 ERISQKSAENGRGGRVLKPVRPLLLPRAAGEPLPTQRGAQEKMGTPAEQAQGERNVPPPK 267
Query: 368 DPPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQPSPTASLESKPYNPF 427
P + L+ ++ PL +S G + ++ ++ + + T S + N
Sbjct: 268 SP--LRLIANAIRRSLEPLLSNSEGGKKAWAKQE-----SKTLPAQACTRSFSLRKTNSN 320
Query: 428 EEEEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPTSSPKTKKRPAPRAPSAS- 486
++ ++ ++ PAL S P +K PA R+P S
Sbjct: 321 KDGDQHSPGRNQSSAFSPPDPAL-RTHSLPNR-------------PSKVFPALRSPPCSK 366
Query: 487 ----PLALHASRLSHSEPPSATPSPALSVESLSSESASQTAGAELLEPPAVPKSSSEPAV 542
P L L + P ++ P P + SS + L+ K +
Sbjct: 367 IEDVPTLLEKVSLQENFPDASKP-PKKRISLFSSLRLKDKSFESFLQESRQRKDIRDLF- 424
Query: 543 HAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAPRTRGSSGPQPAKPCSGATP 602
G+P V L +S+ A L + + QA+P P P P P +G
Sbjct: 425 ---GSPKRKV-LPEDSAQALEKLLQPFKSTSLRQAAPPPPP----PPPPPPPPPTAGGAD 476
Query: 603 TPLLLVGDRSPVPSPGSSSPQLQVKSSCKENPFNRKPSPAASPATKKATKGSKPVRPPAP 662
+ + R+ V SS+ SS + F+ P + KK + K +
Sbjct: 477 SKNFPL--RAQVTEASSSASS--TSSSSADEEFD--PQLSLQLKEKKTLRRRKKLEKAMK 530
Query: 663 GHGFPLIKRKVQADQYIPEEDIHGEMDTIERRLDALEHRGVLLEEKLRGGLNEGREDD-- 720
L+K++ + + + I +++ +E R A E +GV LE+ LRG + G +D+
Sbjct: 531 ----QLVKQE-ELKRLYKAQAIQRQLEEVEERQRASEIQGVRLEKALRGEADSGTQDEAQ 585
Query: 721 MLVDWFKLIHEKHLLVRRESELIYVFKQQNLEQRQADVEYELRCLLNKPEKDWTEEDRAR 780
+L +WFKL+ EK+ L+R ESEL+ + ++ LE Q+ +E +LR + K E E+D
Sbjct: 586 LLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLEQKLREKMLKEESQKDEKDLNE 645
Query: 781 EKVLMQELVTLIEQRNAIINCLDEDRQREEEEDKMLEAMI 820
E+ + EL+ +IEQR+ +++ L+E R RE+ ED+ E+ +
Sbjct: 646 EQEVFTELMQVIEQRDKLVDSLEEQRIREKAEDQHFESFV 685
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.129 0.381
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,113,484
Number of Sequences: 37866
Number of extensions: 3200527
Number of successful extensions: 40671
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 453
Number of HSP's successfully gapped in prelim test: 2826
Number of HSP's that attempted gapping in prelim test: 18921
Number of HSP's gapped (non-prelim): 14910
length of query: 863
length of database: 18,247,518
effective HSP length: 111
effective length of query: 752
effective length of database: 14,044,392
effective search space: 10561382784
effective search space used: 10561382784
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.