Search of human proteins with 30425496

Search of human proteins with 30425496

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|30425496 family with sequence similarity 19 (chemokine (C-C
motif)-like), member A2 [Homo sapiens]
         (131 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|30425496 family with sequence similarity 19 (chemokine (C-C m...   282   5e-77
gi|32698882 family with sequence similarity 19 (chemokine (C-C m...   190   3e-49
gi|53988383 family with sequence similarity 19 (chemokine (C-C m...   190   3e-49
gi|33300649 family with sequence similarity 19 (chemokine (C-C m...   175   1e-44
gi|50962799 family with sequence similarity 19 (chemokine (C-C m...   169   4e-43
gi|53933210 family with sequence similarity 19 (chemokine (C-C m...   104   2e-23
gi|131887988 family with sequence similarity 19 (chemokine (C-C ...   103   5e-23
gi|52486734 family with sequence similarity 19 (chemokine (C-C m...    96   8e-21
gi|4557733 latent transforming growth factor beta binding protei...    33   0.083
gi|8393264 delta-like 3 protein isoform 1 precursor [Homo sapiens]     31   0.32 
gi|45243561 delta-like 3 protein isoform 2 precursor [Homo sapiens]    31   0.32 
gi|41327708 crumbs homolog 1 precursor [Homo sapiens]                  31   0.32 
gi|54873613 agrin [Homo sapiens]                                       30   0.54 
gi|134244285 Notch homolog 3 [Homo sapiens]                            30   0.54 
gi|112420992 crumbs homolog 2 [Homo sapiens]                           30   0.70 
gi|13787217 FAT tumor suppressor 2 precursor [Homo sapiens]            30   0.70 
gi|56237021 fibrillin 3 precursor [Homo sapiens]                       29   1.2  
gi|57242793 interphotoreceptor matrix proteoglycan 2 [Homo sapiens]    28   1.6  
gi|40317628 thrombospondin 2 precursor [Homo sapiens]                  28   2.1  
gi|110347437 latent transforming growth factor beta binding prot...    28   2.1  
gi|110347412 latent transforming growth factor beta binding prot...    28   2.1  
gi|110347431 latent transforming growth factor beta binding prot...    28   2.1  
gi|93102379 low density lipoprotein-related protein 1B precursor...    28   2.7  
gi|111125011 WNT inhibitory factor 1 precursor [Homo sapiens]          27   3.5  
gi|21704279 jagged 2 isoform b precursor [Homo sapiens]                27   4.6  
gi|21704277 jagged 2 isoform a precursor [Homo sapiens]                27   4.6  
gi|55770876 notch4 preproprotein [Homo sapiens]                        27   4.6  
gi|24041035 notch 2 preproprotein [Homo sapiens]                       27   6.0  
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]                    27   6.0  
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]                    27   6.0  

>gi|30425496 family with sequence similarity 19 (chemokine (C-C
           motif)-like), member A2 [Homo sapiens]
          Length = 131

 Score =  282 bits (722), Expect = 5e-77
 Identities = 131/131 (100%), Positives = 131/131 (100%)

Query: 1   MSKRYLQKATKGKLLIIIFIVTLWGKVVSSANHHKAHHVKTGTCEVVALHRCCNKNKIEE 60
           MSKRYLQKATKGKLLIIIFIVTLWGKVVSSANHHKAHHVKTGTCEVVALHRCCNKNKIEE
Sbjct: 1   MSKRYLQKATKGKLLIIIFIVTLWGKVVSSANHHKAHHVKTGTCEVVALHRCCNKNKIEE 60

Query: 61  RSQTVKCSCFPGQVAGTTRAAPSCVDASIVEQKWWCHMQPCLEGEECKVLPDRKGWSCSS 120
           RSQTVKCSCFPGQVAGTTRAAPSCVDASIVEQKWWCHMQPCLEGEECKVLPDRKGWSCSS
Sbjct: 61  RSQTVKCSCFPGQVAGTTRAAPSCVDASIVEQKWWCHMQPCLEGEECKVLPDRKGWSCSS 120

Query: 121 GNKVKTTRVTH 131
           GNKVKTTRVTH
Sbjct: 121 GNKVKTTRVTH 131


>gi|32698882 family with sequence similarity 19 (chemokine (C-C
           motif)-like), member A4 [Homo sapiens]
          Length = 140

 Score =  190 bits (482), Expect = 3e-49
 Identities = 85/121 (70%), Positives = 101/121 (83%), Gaps = 5/121 (4%)

Query: 15  LIIIFIVTLWGKVVSSANHHKA-----HHVKTGTCEVVALHRCCNKNKIEERSQTVKCSC 69
           L + +++ +  K++S+++ H       H +K GTCEVVA+HRCCNKN+IEERSQTVKCSC
Sbjct: 19  LFLAYVLMVCCKLMSASSQHLRGHAGHHQIKQGTCEVVAVHRCCNKNRIEERSQTVKCSC 78

Query: 70  FPGQVAGTTRAAPSCVDASIVEQKWWCHMQPCLEGEECKVLPDRKGWSCSSGNKVKTTRV 129
           FPGQVAGTTRA PSCV+ASIV QKWWCHM PCLEGE+CKVLPD  GWSCSSGNKVKTT+V
Sbjct: 79  FPGQVAGTTRAQPSCVEASIVIQKWWCHMNPCLEGEDCKVLPDYSGWSCSSGNKVKTTKV 138

Query: 130 T 130
           T
Sbjct: 139 T 139


>gi|53988383 family with sequence similarity 19 (chemokine (C-C
           motif)-like), member A4 [Homo sapiens]
          Length = 140

 Score =  190 bits (482), Expect = 3e-49
 Identities = 85/121 (70%), Positives = 101/121 (83%), Gaps = 5/121 (4%)

Query: 15  LIIIFIVTLWGKVVSSANHHKA-----HHVKTGTCEVVALHRCCNKNKIEERSQTVKCSC 69
           L + +++ +  K++S+++ H       H +K GTCEVVA+HRCCNKN+IEERSQTVKCSC
Sbjct: 19  LFLAYVLMVCCKLMSASSQHLRGHAGHHQIKQGTCEVVAVHRCCNKNRIEERSQTVKCSC 78

Query: 70  FPGQVAGTTRAAPSCVDASIVEQKWWCHMQPCLEGEECKVLPDRKGWSCSSGNKVKTTRV 129
           FPGQVAGTTRA PSCV+ASIV QKWWCHM PCLEGE+CKVLPD  GWSCSSGNKVKTT+V
Sbjct: 79  FPGQVAGTTRAQPSCVEASIVIQKWWCHMNPCLEGEDCKVLPDYSGWSCSSGNKVKTTKV 138

Query: 130 T 130
           T
Sbjct: 139 T 139


>gi|33300649 family with sequence similarity 19 (chemokine (C-C
           motif)-like), member A3 isoform 1 [Homo sapiens]
          Length = 133

 Score =  175 bits (443), Expect = 1e-44
 Identities = 83/132 (62%), Positives = 99/132 (75%), Gaps = 2/132 (1%)

Query: 1   MSKRYLQKATKGKLLIIIFIVTLWGKVVSSANHHKAHHV--KTGTCEVVALHRCCNKNKI 58
           MS+R  +  + G  L+ + +  LW  +  +A       V  + GTCEV+A HRCCN+N+I
Sbjct: 1   MSERVERNWSTGGWLLALCLAWLWTHLTLAALQPPTATVLVQQGTCEVIAAHRCCNRNRI 60

Query: 59  EERSQTVKCSCFPGQVAGTTRAAPSCVDASIVEQKWWCHMQPCLEGEECKVLPDRKGWSC 118
           EERSQTVKCSCF GQVAGTTRA PSCVDASIV Q+WWC M+PCL GEECKVLPD  GWSC
Sbjct: 61  EERSQTVKCSCFSGQVAGTTRAKPSCVDASIVLQRWWCQMEPCLPGEECKVLPDLSGWSC 120

Query: 119 SSGNKVKTTRVT 130
           SSG+KVKTT+VT
Sbjct: 121 SSGHKVKTTKVT 132


>gi|50962799 family with sequence similarity 19 (chemokine (C-C
           motif)-like), member A1 [Homo sapiens]
          Length = 133

 Score =  169 bits (429), Expect = 4e-43
 Identities = 72/105 (68%), Positives = 83/105 (79%)

Query: 25  GKVVSSANHHKAHHVKTGTCEVVALHRCCNKNKIEERSQTVKCSCFPGQVAGTTRAAPSC 84
           G +  +   H  H  + GTCEV+A HRCCNKN+IEERSQTVKCSC PG+VAGTTR  PSC
Sbjct: 25  GSLQHTFQQHHLHRPEGGTCEVIAAHRCCNKNRIEERSQTVKCSCLPGKVAGTTRNRPSC 84

Query: 85  VDASIVEQKWWCHMQPCLEGEECKVLPDRKGWSCSSGNKVKTTRV 129
           VDASIV  KWWC M+PCLEGEECK LPD  GW C++GNK+KTTR+
Sbjct: 85  VDASIVIGKWWCEMEPCLEGEECKTLPDNSGWMCATGNKIKTTRI 129


>gi|53933210 family with sequence similarity 19 (chemokine (C-C
           motif)-like), member A5 isoform 2 [Homo sapiens]
          Length = 125

 Score =  104 bits (260), Expect = 2e-23
 Identities = 49/105 (46%), Positives = 68/105 (64%), Gaps = 1/105 (0%)

Query: 27  VVSSANHHKAHHVKTGTCEVVALHRCCNKNKIEERSQTVKCSCFPGQVAGTTRAAPSCVD 86
           +V  A   K   +  GTCE+V L R  ++ +     QT +C+C  GQ+AGTTRA P+CVD
Sbjct: 21  LVIHAQFLKEGQLAAGTCEIVTLDRDSSQPRRTIARQTARCACRKGQIAGTTRARPACVD 80

Query: 87  ASIVEQKWWCHMQPCLEGEECKVLPDRKGWSCSS-GNKVKTTRVT 130
           A I++ K WC M PCLEGE C +L +R GW+C+  G ++KTT V+
Sbjct: 81  ARIIKTKQWCDMLPCLEGEGCDLLINRSGWTCTQPGGRIKTTTVS 125


>gi|131887988 family with sequence similarity 19 (chemokine (C-C
           motif)-like), member A5 isoform 1 [Homo sapiens]
          Length = 132

 Score =  103 bits (256), Expect = 5e-23
 Identities = 46/90 (51%), Positives = 63/90 (70%), Gaps = 1/90 (1%)

Query: 42  GTCEVVALHRCCNKNKIEERSQTVKCSCFPGQVAGTTRAAPSCVDASIVEQKWWCHMQPC 101
           GTCE+V L R  ++ +     QT +C+C  GQ+AGTTRA P+CVDA I++ K WC M PC
Sbjct: 43  GTCEIVTLDRDSSQPRRTIARQTARCACRKGQIAGTTRARPACVDARIIKTKQWCDMLPC 102

Query: 102 LEGEECKVLPDRKGWSCSS-GNKVKTTRVT 130
           LEGE C +L +R GW+C+  G ++KTT V+
Sbjct: 103 LEGEGCDLLINRSGWTCTQPGGRIKTTTVS 132


>gi|52486734 family with sequence similarity 19 (chemokine (C-C
          motif)-like), member A3 isoform 2 [Homo sapiens]
          Length = 169

 Score = 95.9 bits (237), Expect = 8e-21
 Identities = 48/88 (54%), Positives = 60/88 (68%), Gaps = 2/88 (2%)

Query: 1  MSKRYLQKATKGKLLIIIFIVTLWGKVVSSANHHKAHHV--KTGTCEVVALHRCCNKNKI 58
          MS+R  +  + G  L+ + +  LW  +  +A       V  + GTCEV+A HRCCN+N+I
Sbjct: 1  MSERVERNWSTGGWLLALCLAWLWTHLTLAALQPPTATVLVQQGTCEVIAAHRCCNRNRI 60

Query: 59 EERSQTVKCSCFPGQVAGTTRAAPSCVD 86
          EERSQTVKCSCF GQVAGTTRA PSCVD
Sbjct: 61 EERSQTVKCSCFSGQVAGTTRAKPSCVD 88


>gi|4557733 latent transforming growth factor beta binding protein 2
           [Homo sapiens]
          Length = 1821

 Score = 32.7 bits (73), Expect = 0.083
 Identities = 16/54 (29%), Positives = 21/54 (38%)

Query: 52  CCNKNKIEERSQTVKCSCFPGQVAGTTRAAPSCVDASIVEQKWWCHMQPCLEGE 105
           C  K +   R  +  C C+PG    T+ A   C D +  EQ   C    C   E
Sbjct: 896 CKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTE 949


>gi|8393264 delta-like 3 protein isoform 1 precursor [Homo sapiens]
          Length = 618

 Score = 30.8 bits (68), Expect = 0.32
 Identities = 18/74 (24%), Positives = 30/74 (40%), Gaps = 12/74 (16%)

Query: 52  CCNKNKIEERSQTVKCSCFPG------QVAGTTRAAPSCVDASIV------EQKWWCHMQ 99
           C N     E  ++ +C+C  G      +V+G T A   C +  +       +  + CH  
Sbjct: 283 CANGGSCSETPRSFECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGADPDSAYICHCP 342

Query: 100 PCLEGEECKVLPDR 113
           P  +G  C+   DR
Sbjct: 343 PGFQGSNCEKRVDR 356


>gi|45243561 delta-like 3 protein isoform 2 precursor [Homo sapiens]
          Length = 587

 Score = 30.8 bits (68), Expect = 0.32
 Identities = 18/74 (24%), Positives = 30/74 (40%), Gaps = 12/74 (16%)

Query: 52  CCNKNKIEERSQTVKCSCFPG------QVAGTTRAAPSCVDASIV------EQKWWCHMQ 99
           C N     E  ++ +C+C  G      +V+G T A   C +  +       +  + CH  
Sbjct: 283 CANGGSCSETPRSFECTCPRGFYGLRCEVSGVTCADGPCFNGGLCVGGADPDSAYICHCP 342

Query: 100 PCLEGEECKVLPDR 113
           P  +G  C+   DR
Sbjct: 343 PGFQGSNCEKRVDR 356


>gi|41327708 crumbs homolog 1 precursor [Homo sapiens]
          Length = 1406

 Score = 30.8 bits (68), Expect = 0.32
 Identities = 17/67 (25%), Positives = 23/67 (34%), Gaps = 14/67 (20%)

Query: 52  CCNKNKIEERSQTVKCSCFPGQVAGTTRAAPSCVDASIVEQKWWCHMQPCLEGEECKVLP 111
           C N      R     CSC            P+       E+  WC   PC  G +C+  P
Sbjct: 896 CHNGGVCHSRWDDFSCSC------------PALTSGKACEEVQWCGFSPCPHGAQCQ--P 941

Query: 112 DRKGWSC 118
             +G+ C
Sbjct: 942 VLQGFEC 948


>gi|54873613 agrin [Homo sapiens]
          Length = 2045

 Score = 30.0 bits (66), Expect = 0.54
 Identities = 16/46 (34%), Positives = 21/46 (45%), Gaps = 11/46 (23%)

Query: 67   CSCFPGQVAGTTRAAPSCVDASIVEQKWWCHMQPCLEGEECKVLPD 112
            C C PG+V       P+C D     +K  C   PC     C+VLP+
Sbjct: 1574 CQCPPGRVG------PTCAD-----EKSPCQPNPCHGAAPCRVLPE 1608


>gi|134244285 Notch homolog 3 [Homo sapiens]
          Length = 2321

 Score = 30.0 bits (66), Expect = 0.54
 Identities = 20/69 (28%), Positives = 27/69 (39%), Gaps = 11/69 (15%)

Query: 53  CNKNKIEERSQTVKCSCFPGQVAGTTRAAPSCVDASIVEQKWWCHMQPCLEGEECKVLPD 112
           C+  +  +   +  C+C PG    T     S VD         C  QPC  G +C  L D
Sbjct: 554 CHHGRCVDGIASFSCACAPGY---TGTRCESQVDE--------CRSQPCRHGGKCLDLVD 602

Query: 113 RKGWSCSSG 121
           +    C SG
Sbjct: 603 KYLCRCPSG 611



 Score = 28.1 bits (61), Expect = 2.1
 Identities = 15/41 (36%), Positives = 18/41 (43%), Gaps = 11/41 (26%)

Query: 74  VAGTTRAAPSCVDASIVEQKWWCHMQPCLEGEECKVLPDRK 114
           +AG   AAP C+D S           PC  G  C  LP R+
Sbjct: 33  LAGPGAAAPPCLDGS-----------PCANGGRCTQLPSRE 62



 Score = 27.7 bits (60), Expect = 2.7
 Identities = 22/67 (32%), Positives = 28/67 (41%), Gaps = 10/67 (14%)

Query: 69  CFPGQVAGTTRAAPSCV------DASIVEQKWWCHMQPCLEGEECKVLPD-RKGWSCSSG 121
           C    VAGT R +  C       D S+ +    C   PC  G  C V PD R   SC  G
Sbjct: 93  CQSSVVAGTARFSCRCPRGFRGPDCSLPDP---CLSSPCAHGARCSVGPDGRFLCSCPPG 149

Query: 122 NKVKTTR 128
            + ++ R
Sbjct: 150 YQGRSCR 156



 Score = 26.6 bits (57), Expect = 6.0
 Identities = 14/54 (25%), Positives = 22/54 (40%), Gaps = 3/54 (5%)

Query: 66   KCSCFPGQVAGTTRAAPSCVDASIVEQKWWCHMQPCLEGEECKVLPDRKGWSCS 119
            +C+C PG    + R+ P     +       C   PCL G  C+  P    + C+
Sbjct: 1312 RCACPPGLSGPSCRSFPGSPPGASNAS---CAAAPCLHGGSCRPAPLAPFFRCA 1362


>gi|112420992 crumbs homolog 2 [Homo sapiens]
          Length = 1285

 Score = 29.6 bits (65), Expect = 0.70
 Identities = 18/52 (34%), Positives = 24/52 (46%), Gaps = 14/52 (26%)

Query: 67  CSCFPGQVAGTTRAAPSCVDASIVEQKWWCHMQPCLEGEECKVLPDRKGWSC 118
           C+C P    G     P+C       Q+ WC  QPCL    C+ +PD  G+ C
Sbjct: 831 CTC-PANFTG-----PTCA------QQLWCPGQPCLPPATCEEVPD--GFVC 868



 Score = 26.2 bits (56), Expect = 7.8
 Identities = 16/57 (28%), Positives = 21/57 (36%), Gaps = 11/57 (19%)

Query: 52   CCNKNKIEERSQTVKCSCFPGQVAGTTRAAPSCVDASIVEQKWWCHMQPCLEGEECK 108
            C + +  E  S    CSC  G +AG     P+            C   PCL G  C+
Sbjct: 1144 CLDGSPCEGGSPAANCSCLEG-LAGQRCQVPTLP----------CEANPCLNGGTCR 1189


>gi|13787217 FAT tumor suppressor 2 precursor [Homo sapiens]
          Length = 4349

 Score = 29.6 bits (65), Expect = 0.70
 Identities = 27/82 (32%), Positives = 35/82 (42%), Gaps = 8/82 (9%)

Query: 42   GTCEVVALHRCCNKNKIEERSQTV---KCSCFPGQVAGTTRAAPSCVDASIVEQ-KWWCH 97
            G  E  AL +CC  +    ++  +   KCS   G  AG     P        EQ +  C 
Sbjct: 3934 GLLETQALTQCCLHSDYCSQNTCLNGGKCSWTHG--AGYVCKCPPQFSGKHCEQGRENCT 3991

Query: 98   MQPCLEGEECKVLPDRKGWSCS 119
              PCLEG  C + P  KG SC+
Sbjct: 3992 FAPCLEGGTCILSP--KGASCN 4011


>gi|56237021 fibrillin 3 precursor [Homo sapiens]
          Length = 2809

 Score = 28.9 bits (63), Expect = 1.2
 Identities = 17/42 (40%), Positives = 20/42 (47%), Gaps = 1/42 (2%)

Query: 64  TVKCSCFPGQVAGTTRAAPSCVDASIVEQKWWCHMQPCLEGE 105
           T  C C+PG  A  TR A   VD  IV     CH+  C+  E
Sbjct: 469 TYHCRCYPGFQATPTRQACVDVDECIV-SGGLCHLGRCVNTE 509


>gi|57242793 interphotoreceptor matrix proteoglycan 2 [Homo sapiens]
          Length = 1241

 Score = 28.5 bits (62), Expect = 1.6
 Identities = 16/52 (30%), Positives = 22/52 (42%), Gaps = 13/52 (25%)

Query: 62   SQTVKCSCFPGQVAGTTRAAPSCVDASIVEQKWWCHMQP--CLEGEECKVLP 111
            S   KC CFPG ++   R   S            C +QP  CL   +C ++P
Sbjct: 1031 SGEAKCRCFPGYLSVEERPCQSL-----------CDLQPDFCLNDGKCDIMP 1071


>gi|40317628 thrombospondin 2 precursor [Homo sapiens]
          Length = 1172

 Score = 28.1 bits (61), Expect = 2.1
 Identities = 11/25 (44%), Positives = 12/25 (48%), Gaps = 1/25 (4%)

Query: 96  CHMQPCLEGEECKVLPDRKGWSCSS 120
           C   PC  G +C   PD   WSC S
Sbjct: 553 CLSNPCFPGAQCSSFPD-GSWSCGS 576


>gi|110347437 latent transforming growth factor beta binding protein
           4 isoform c [Homo sapiens]
          Length = 1557

 Score = 28.1 bits (61), Expect = 2.1
 Identities = 21/76 (27%), Positives = 27/76 (35%), Gaps = 17/76 (22%)

Query: 37  HHVKTGTCEVV-----ALHRCCNKNKIEERSQTVKCSCFPGQVAGTTRAAPSCVDASIVE 91
           HH+  G C  V         C           + +CSC PG  A + R  P C D     
Sbjct: 758 HHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP-CAD----- 811

Query: 92  QKWWCHMQPCLEGEEC 107
                 +  CLEG+ C
Sbjct: 812 ------VNECLEGDFC 821


>gi|110347412 latent transforming growth factor beta binding protein
           4 isoform b [Homo sapiens]
          Length = 1587

 Score = 28.1 bits (61), Expect = 2.1
 Identities = 21/76 (27%), Positives = 27/76 (35%), Gaps = 17/76 (22%)

Query: 37  HHVKTGTCEVV-----ALHRCCNKNKIEERSQTVKCSCFPGQVAGTTRAAPSCVDASIVE 91
           HH+  G C  V         C           + +CSC PG  A + R  P C D     
Sbjct: 788 HHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP-CAD----- 841

Query: 92  QKWWCHMQPCLEGEEC 107
                 +  CLEG+ C
Sbjct: 842 ------VNECLEGDFC 851


>gi|110347431 latent transforming growth factor beta binding protein
           4 isoform a [Homo sapiens]
          Length = 1624

 Score = 28.1 bits (61), Expect = 2.1
 Identities = 21/76 (27%), Positives = 27/76 (35%), Gaps = 17/76 (22%)

Query: 37  HHVKTGTCEVV-----ALHRCCNKNKIEERSQTVKCSCFPGQVAGTTRAAPSCVDASIVE 91
           HH+  G C  V         C           + +CSC PG  A + R  P C D     
Sbjct: 825 HHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGP-CAD----- 878

Query: 92  QKWWCHMQPCLEGEEC 107
                 +  CLEG+ C
Sbjct: 879 ------VNECLEGDFC 888


>gi|93102379 low density lipoprotein-related protein 1B precursor
            [Homo sapiens]
          Length = 4599

 Score = 27.7 bits (60), Expect = 2.7
 Identities = 15/34 (44%), Positives = 18/34 (52%), Gaps = 6/34 (17%)

Query: 43   TCEVVALHRCCNKNKI----EERSQTVKCSCFPG 72
            TCE+V    C N  K     E+   TVKCSC+ G
Sbjct: 1211 TCEIVDY--CSNHLKCSQVCEQHKHTVKCSCYEG 1242


>gi|111125011 WNT inhibitory factor 1 precursor [Homo sapiens]
          Length = 379

 Score = 27.3 bits (59), Expect = 3.5
 Identities = 18/69 (26%), Positives = 27/69 (39%), Gaps = 7/69 (10%)

Query: 67  CSCFPGQVA---GTTRAAPSCVDASIVEQKWWCHMQPCLEGEECKV----LPDRKGWSCS 119
           C C PG           + +C +         C   P LEGE+C++     P R G  C 
Sbjct: 230 CICPPGFYGVNCDKANCSTTCFNGGTCFYPGKCICPPGLEGEQCEISKCPQPCRNGGKCI 289

Query: 120 SGNKVKTTR 128
             +K K ++
Sbjct: 290 GKSKCKCSK 298


>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
          Length = 1200

 Score = 26.9 bits (58), Expect = 4.6
 Identities = 17/73 (23%), Positives = 25/73 (34%), Gaps = 13/73 (17%)

Query: 35  KAHHVKTGTCEVVALHRCCNKNKIEERSQTVKCSCFPGQVAGTTRAAPSCVDASIVEQKW 94
           K  H +   C+    + C N     +   T +C+C PG    T   A +           
Sbjct: 669 KTCHSREFQCDA---YTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSS--------- 716

Query: 95  WCHMQPCLEGEEC 107
            C   PC+ G  C
Sbjct: 717 -CLPNPCVNGGTC 728


>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
          Length = 1238

 Score = 26.9 bits (58), Expect = 4.6
 Identities = 17/73 (23%), Positives = 25/73 (34%), Gaps = 13/73 (17%)

Query: 35  KAHHVKTGTCEVVALHRCCNKNKIEERSQTVKCSCFPGQVAGTTRAAPSCVDASIVEQKW 94
           K  H +   C+    + C N     +   T +C+C PG    T   A +           
Sbjct: 707 KTCHSREFQCDA---YTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSS--------- 754

Query: 95  WCHMQPCLEGEEC 107
            C   PC+ G  C
Sbjct: 755 -CLPNPCVNGGTC 766


>gi|55770876 notch4 preproprotein [Homo sapiens]
          Length = 2003

 Score = 26.9 bits (58), Expect = 4.6
 Identities = 19/70 (27%), Positives = 24/70 (34%), Gaps = 11/70 (15%)

Query: 52  CCNKNKIEERSQTVKCSCFPGQVAGTTRAAPSCVDASIVEQKWWCHMQPCLEGEECKVLP 111
           C N  + +++     C C PG         P C    + E    C   PC  G  C  LP
Sbjct: 560 CANGGQCQDQPGAFHCKCLPG------FEGPRC-QTEVDE----CLSDPCPVGASCLDLP 608

Query: 112 DRKGWSCSSG 121
                 C SG
Sbjct: 609 GAFFCLCPSG 618



 Score = 26.6 bits (57), Expect = 6.0
 Identities = 16/53 (30%), Positives = 24/53 (45%), Gaps = 4/53 (7%)

Query: 68  SCFPGQVAGTTRAAPS-CVDASIVEQKWWCHMQPCLEGEECKVLPDRKGWSCS 119
           +C+P Q +G     P+     +  E+   CH  PCL G  C   P   G+ C+
Sbjct: 705 TCYP-QPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCN--PSPGGYYCT 754


>gi|24041035 notch 2 preproprotein [Homo sapiens]
          Length = 2471

 Score = 26.6 bits (57), Expect = 6.0
 Identities = 18/71 (25%), Positives = 27/71 (38%), Gaps = 13/71 (18%)

Query: 52  CCNKNKIEERSQTVKCSCFPGQVAGTTRAAPSC-VDASIVEQKWWCHMQPCLEGEECKVL 110
           C N  +  ++    +C C PG         P C +D         C   PCL G +C   
Sbjct: 503 CVNNGQCVDKVNRFQCLCPPGFTG------PVCQIDIDD------CSSTPCLNGAKCIDH 550

Query: 111 PDRKGWSCSSG 121
           P+     C++G
Sbjct: 551 PNGYECQCATG 561


>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3874

 Score = 26.6 bits (57), Expect = 6.0
 Identities = 14/35 (40%), Positives = 18/35 (51%), Gaps = 4/35 (11%)

Query: 52   CCNKNKIEERSQTVKCSCFPGQVAGTTRAAPSCVD 86
            C + N+ EE S      C PGQ+   TR +  CVD
Sbjct: 3716 CQDINECEEES----IECGPGQMCFNTRGSYQCVD 3746


>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 5065

 Score = 26.6 bits (57), Expect = 6.0
 Identities = 14/35 (40%), Positives = 18/35 (51%), Gaps = 4/35 (11%)

Query: 52   CCNKNKIEERSQTVKCSCFPGQVAGTTRAAPSCVD 86
            C + N+ EE S      C PGQ+   TR +  CVD
Sbjct: 4907 CQDINECEEES----IECGPGQMCFNTRGSYQCVD 4937


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.130    0.433 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,113,134
Number of Sequences: 37866
Number of extensions: 206851
Number of successful extensions: 605
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 15
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 546
Number of HSP's gapped (non-prelim): 86
length of query: 131
length of database: 18,247,518
effective HSP length: 91
effective length of query: 40
effective length of database: 14,801,712
effective search space: 592068480
effective search space used: 592068480
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 56 (26.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.