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Search of human proteins with 30425368
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|30425368 parathyroid hormone 2 preproprotein [Homo sapiens]
(100 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|30425368 parathyroid hormone 2 preproprotein [Homo sapiens] 199 3e-52
gi|38570064 hypothetical protein LOC136895 [Homo sapiens] 32 0.14
gi|38569419 AAT1-alpha [Homo sapiens] 29 0.70
gi|194578898 hypothetical protein LOC100170841 [Homo sapiens] 29 0.92
gi|4505353 heparan glucosaminyl N-deacetylase/N-sulfotransferase... 28 1.6
gi|93204879 PR domain containing 15 isoform 1 [Homo sapiens] 28 1.6
gi|239741271 PREDICTED: hypothetical protein [Homo sapiens] 28 2.0
gi|194248068 synaptic Ras GTPase activating protein 1 [Homo sapi... 28 2.0
gi|10864029 junctional adhesion molecule 2 precursor [Homo sapiens] 28 2.0
gi|126032348 hect domain and RLD 2 [Homo sapiens] 27 2.7
gi|39930315 neurexophilin 4 [Homo sapiens] 27 2.7
gi|115647957 torsin family 3, member A [Homo sapiens] 27 2.7
gi|18252045 ADAM metallopeptidase domain 33 isoform alpha prepro... 27 3.5
gi|24041040 ADAM metallopeptidase domain 33 isoform beta preprop... 27 3.5
gi|153792110 HEG homolog 1 [Homo sapiens] 27 3.5
gi|148727264 transcription elongation regulator 1-like [Homo sap... 27 3.5
gi|27735067 hypothetical protein LOC126353 [Homo sapiens] 27 3.5
gi|119392086 Indian hedgehog homolog [Homo sapiens] 26 5.9
gi|239757232 PREDICTED: hypothetical protein [Homo sapiens] 26 5.9
gi|239751740 PREDICTED: hypothetical protein [Homo sapiens] 26 5.9
gi|239746241 PREDICTED: hypothetical protein XP_002343712 [Homo ... 26 5.9
gi|40255245 G protein-coupled receptor 51 [Homo sapiens] 26 5.9
gi|56549696 E1A binding protein p400 [Homo sapiens] 26 5.9
gi|28212222 WFIKKN2 protein [Homo sapiens] 26 5.9
gi|50658079 tubulin tyrosine ligase-like family, member 5 [Homo ... 26 5.9
gi|239754297 PREDICTED: hypothetical protein [Homo sapiens] 26 7.8
gi|239752695 PREDICTED: hypothetical protein XP_002345326 [Homo ... 26 7.8
gi|239748836 PREDICTED: hypothetical protein XP_002346833 [Homo ... 26 7.8
gi|239747673 PREDICTED: doublecortin domain-containing protein E... 26 7.8
gi|239747229 PREDICTED: hypothetical protein XP_002346943 [Homo ... 26 7.8
>gi|30425368 parathyroid hormone 2 preproprotein [Homo sapiens]
Length = 100
Score = 199 bits (507), Expect = 3e-52
Identities = 100/100 (100%), Positives = 100/100 (100%)
Query: 1 METRQVSRSPRVRLLLLLLLLLVVPWGVRTASGVALPPVGVLSLRPPGRAWADPATPRPR 60
METRQVSRSPRVRLLLLLLLLLVVPWGVRTASGVALPPVGVLSLRPPGRAWADPATPRPR
Sbjct: 1 METRQVSRSPRVRLLLLLLLLLVVPWGVRTASGVALPPVGVLSLRPPGRAWADPATPRPR 60
Query: 61 RSLALADDAAFRERARLLAALERRHWLNSYMHKLLVLDAP 100
RSLALADDAAFRERARLLAALERRHWLNSYMHKLLVLDAP
Sbjct: 61 RSLALADDAAFRERARLLAALERRHWLNSYMHKLLVLDAP 100
>gi|38570064 hypothetical protein LOC136895 [Homo sapiens]
Length = 590
Score = 31.6 bits (70), Expect = 0.14
Identities = 16/39 (41%), Positives = 18/39 (46%)
Query: 54 PATPRPRRSLALADDAAFRERARLLAALERRHWLNSYMH 92
P T P SL D + A + LER HWL SY H
Sbjct: 245 PKTFAPNTSLNSWDPICSAKEANIQRNLERSHWLTSYTH 283
>gi|38569419 AAT1-alpha [Homo sapiens]
Length = 767
Score = 29.3 bits (64), Expect = 0.70
Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 9/69 (13%)
Query: 18 LLLLLVVPWGVRTASGVALPPVGVLSLRPPGRAWADPATPRPRRSLALADDAAFRERARL 77
LL L + WG +G A V ++ RAW + + P AL+D + F +R ++
Sbjct: 219 LLTLATLTWGRGLPAGQA--EVEMIERAREKRAW-EASLP------ALSDTSQFEKRRKM 269
Query: 78 LAALERRHW 86
+ +ER+ W
Sbjct: 270 MNEMERKEW 278
>gi|194578898 hypothetical protein LOC100170841 [Homo sapiens]
Length = 379
Score = 28.9 bits (63), Expect = 0.92
Identities = 16/36 (44%), Positives = 16/36 (44%), Gaps = 3/36 (8%)
Query: 27 GVRTASGVALPPVGVLSLRPPGRAWADPATPRPRRS 62
G G P GV S PPGR PA P PR S
Sbjct: 117 GEEEEGGGGFPHFGVRSCAPPGRC---PAPPHPRES 149
>gi|4505353 heparan glucosaminyl N-deacetylase/N-sulfotransferase 2
[Homo sapiens]
Length = 883
Score = 28.1 bits (61), Expect = 1.6
Identities = 21/74 (28%), Positives = 32/74 (43%), Gaps = 4/74 (5%)
Query: 26 WGVRTASGVALPPVGVLSLRPPGRAWADPATPRPRRSLALADDAAFRERARLLAALERRH 85
W + ++ PV + SLRP A P R R + D R+L H
Sbjct: 227 WTIFQSNHSTYEPVLLASLRPAEPAVPGPVLRRARLPTVVQDLGLHDGIQRVLFG----H 282
Query: 86 WLNSYMHKLLVLDA 99
L+ ++HKL+ +DA
Sbjct: 283 GLSFWLHKLIFVDA 296
>gi|93204879 PR domain containing 15 isoform 1 [Homo sapiens]
Length = 1507
Score = 28.1 bits (61), Expect = 1.6
Identities = 15/34 (44%), Positives = 19/34 (55%), Gaps = 5/34 (14%)
Query: 26 WGVRTASGVALPPVGVLSLRPPGRAWADPATPRP 59
W R+ SG+AL + RPPG + PA PRP
Sbjct: 66 WISRSRSGIALR-----AARPPGSSPPRPAAPRP 94
>gi|239741271 PREDICTED: hypothetical protein [Homo sapiens]
Length = 274
Score = 27.7 bits (60), Expect = 2.0
Identities = 14/21 (66%), Positives = 14/21 (66%), Gaps = 1/21 (4%)
Query: 47 PGRAWADPATPRPRRSLALAD 67
PGR W D AT RP R ALAD
Sbjct: 112 PGRGWRDSAT-RPGRPRALAD 131
>gi|194248068 synaptic Ras GTPase activating protein 1 [Homo sapiens]
Length = 1343
Score = 27.7 bits (60), Expect = 2.0
Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 5/44 (11%)
Query: 36 LPPVGV----LSLRPPGRAWADPATPRPRRSLALADDAAFRERA 75
LPP+G ++L PP A PA P P R L + ++ FR A
Sbjct: 1299 LPPLGPTNPRVTLAPPWNGLAPPAPPPPPR-LQITENGEFRNTA 1341
>gi|10864029 junctional adhesion molecule 2 precursor [Homo
sapiens]
Length = 298
Score = 27.7 bits (60), Expect = 2.0
Identities = 16/32 (50%), Positives = 19/32 (59%)
Query: 6 VSRSPRVRLLLLLLLLLVVPWGVRTASGVALP 37
++R R RLLLLLL LVV G A G + P
Sbjct: 1 MARRSRHRLLLLLLRYLVVALGYHKAYGFSAP 32
>gi|126032348 hect domain and RLD 2 [Homo sapiens]
Length = 4834
Score = 27.3 bits (59), Expect = 2.7
Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 2/45 (4%)
Query: 31 ASGVALPPVGVLSLRPPGRAWADPATPRPRRSLALADDAAFRERA 75
+SG++LPPV S RP G+ A R +L+ A AF RA
Sbjct: 169 SSGISLPPVDKKSSRPAGKGVEGLARVGSRAALSFA--FAFLRRA 211
>gi|39930315 neurexophilin 4 [Homo sapiens]
Length = 308
Score = 27.3 bits (59), Expect = 2.7
Identities = 21/56 (37%), Positives = 24/56 (42%), Gaps = 5/56 (8%)
Query: 12 VRLLLLLLLLLVVPWGVRTASGVALPPVG---VLSLRPPGRAWADPA--TPRPRRS 62
+RLL LLL PW +R A +P G L LRP P P PR S
Sbjct: 1 MRLLPEWFLLLFGPWLLRKAVSAQIPESGRPQYLGLRPAAAGAGAPGQQLPEPRSS 56
>gi|115647957 torsin family 3, member A [Homo sapiens]
Length = 397
Score = 27.3 bits (59), Expect = 2.7
Identities = 25/79 (31%), Positives = 31/79 (39%), Gaps = 18/79 (22%)
Query: 8 RSPRVRLLLLLLLLLVVPWGVRTASGVALPPVGVLSLRPPGRAWADPATPRPRRSLALAD 67
R P +L L LLLL G G + P G PG AWA P R
Sbjct: 3 RGPWRQLWLFFLLLLP---GAPEPRGASRPWEGT---DEPGSAWAWPGFQR--------- 47
Query: 68 DAAFRERARLLAALERRHW 86
+E+ R AL +R+W
Sbjct: 48 ---LQEQLRAAGALSKRYW 63
>gi|18252045 ADAM metallopeptidase domain 33 isoform alpha
preproprotein [Homo sapiens]
Length = 813
Score = 26.9 bits (58), Expect = 3.5
Identities = 30/89 (33%), Positives = 39/89 (43%), Gaps = 29/89 (32%)
Query: 14 LLLLLLLLLVVPWGVRTASGVALPPVGVLSLRPPGRAWADPATP------RPRRSLALAD 67
LLLLLLLLL+ P +P GVL PG+ P TP +P R+++L +
Sbjct: 13 LLLLLLLLLLWP----------VPGAGVLQGHIPGQ----PVTPHWVLDGQPWRTVSLEE 58
Query: 68 D---------AAFRERARLLAALERRHWL 87
A E LL LE+ H L
Sbjct: 59 PVSKPDMGLVALEAEGQELLLELEKNHRL 87
>gi|24041040 ADAM metallopeptidase domain 33 isoform beta
preproprotein [Homo sapiens]
Length = 787
Score = 26.9 bits (58), Expect = 3.5
Identities = 30/89 (33%), Positives = 39/89 (43%), Gaps = 29/89 (32%)
Query: 14 LLLLLLLLLVVPWGVRTASGVALPPVGVLSLRPPGRAWADPATP------RPRRSLALAD 67
LLLLLLLLL+ P +P GVL PG+ P TP +P R+++L +
Sbjct: 13 LLLLLLLLLLWP----------VPGAGVLQGHIPGQ----PVTPHWVLDGQPWRTVSLEE 58
Query: 68 D---------AAFRERARLLAALERRHWL 87
A E LL LE+ H L
Sbjct: 59 PVSKPDMGLVALEAEGQELLLELEKNHRL 87
>gi|153792110 HEG homolog 1 [Homo sapiens]
Length = 1381
Score = 26.9 bits (58), Expect = 3.5
Identities = 26/76 (34%), Positives = 30/76 (39%), Gaps = 12/76 (15%)
Query: 1 METRQVSRSPRVRLLLLLLLLLVVPWGVRTASGVALPPVGVLSLRPPGRAWAD------- 53
M + + SR P LLLLL LLL+ P T P LSL P A +
Sbjct: 1 MASPRASRWPPPLLLLLLPLLLLPPAAPGTRDPPPSPARRALSLAPLAGAGLELQLERRP 60
Query: 54 -----PATPRPRRSLA 64
P PR RR A
Sbjct: 61 EREPPPTPPRERRGPA 76
>gi|148727264 transcription elongation regulator 1-like [Homo
sapiens]
Length = 586
Score = 26.9 bits (58), Expect = 3.5
Identities = 22/68 (32%), Positives = 30/68 (44%), Gaps = 9/68 (13%)
Query: 28 VRTASGVALPPVGVLSLRPPGR-------AWADPATP-RPRRSLALADDAAFRERARLLA 79
+R ++GV +PPV + S PP W P+ P P L A D+A A
Sbjct: 50 LRLSAGVVVPPVLLASAPPPAAPLLPGLPGWPAPSEPVLPLLPLPSAPDSAAAAAAHPFP 109
Query: 80 ALERRHWL 87
AL + WL
Sbjct: 110 ALHGQ-WL 116
>gi|27735067 hypothetical protein LOC126353 [Homo sapiens]
Length = 679
Score = 26.9 bits (58), Expect = 3.5
Identities = 13/31 (41%), Positives = 18/31 (58%)
Query: 53 DPATPRPRRSLALADDAAFRERARLLAALER 83
DP TP P RS L ++ RE+ LAA ++
Sbjct: 169 DPRTPGPPRSTPLEENVVDREQIDFLAARQQ 199
>gi|119392086 Indian hedgehog homolog [Homo sapiens]
Length = 411
Score = 26.2 bits (56), Expect = 5.9
Identities = 13/20 (65%), Positives = 15/20 (75%), Gaps = 2/20 (10%)
Query: 10 PRVRLLLLLLLLLVVP--WG 27
PR+ L+LLLLLVVP WG
Sbjct: 8 PRLHFCLVLLLLLVVPAAWG 27
>gi|239757232 PREDICTED: hypothetical protein [Homo sapiens]
Length = 461
Score = 26.2 bits (56), Expect = 5.9
Identities = 15/35 (42%), Positives = 17/35 (48%)
Query: 25 PWGVRTASGVALPPVGVLSLRPPGRAWADPATPRP 59
P G R A G+ L PVG S R A + P RP
Sbjct: 412 PRGTRRARGLQLRPVGGQSRREAAPACSGPQPCRP 446
>gi|239751740 PREDICTED: hypothetical protein [Homo sapiens]
Length = 461
Score = 26.2 bits (56), Expect = 5.9
Identities = 15/35 (42%), Positives = 17/35 (48%)
Query: 25 PWGVRTASGVALPPVGVLSLRPPGRAWADPATPRP 59
P G R A G+ L PVG S R A + P RP
Sbjct: 412 PRGTRRARGLQLRPVGGQSRREAAPACSGPQPCRP 446
>gi|239746241 PREDICTED: hypothetical protein XP_002343712 [Homo
sapiens]
Length = 461
Score = 26.2 bits (56), Expect = 5.9
Identities = 15/35 (42%), Positives = 17/35 (48%)
Query: 25 PWGVRTASGVALPPVGVLSLRPPGRAWADPATPRP 59
P G R A G+ L PVG S R A + P RP
Sbjct: 412 PRGTRRARGLQLRPVGGQSRREAAPACSGPQPCRP 446
>gi|40255245 G protein-coupled receptor 51 [Homo sapiens]
Length = 941
Score = 26.2 bits (56), Expect = 5.9
Identities = 17/45 (37%), Positives = 24/45 (53%), Gaps = 8/45 (17%)
Query: 10 PRVRLLLLLLLLLVVP-----WGVRTAS---GVALPPVGVLSLRP 46
P RLLLLLLL L++P WG + + PP+ ++ L P
Sbjct: 19 PPARLLLLLLLPLLLPLAPGAWGWARGAPRPPPSSPPLSIMGLMP 63
>gi|56549696 E1A binding protein p400 [Homo sapiens]
Length = 3122
Score = 26.2 bits (56), Expect = 5.9
Identities = 15/37 (40%), Positives = 18/37 (48%), Gaps = 2/37 (5%)
Query: 23 VVPWGVRTASGVALPPVGVLSLRPPGRAWADPATPRP 59
V P + T G A P V+ +PP RA PAT P
Sbjct: 2621 VAPGALTTPGGSA--PAQVVHTQPPPRAVGSPATATP 2655
>gi|28212222 WFIKKN2 protein [Homo sapiens]
Length = 576
Score = 26.2 bits (56), Expect = 5.9
Identities = 17/33 (51%), Positives = 20/33 (60%), Gaps = 5/33 (15%)
Query: 7 SRSPRVRLLLLLLLLLVVPWGVRTASGVALPPV 39
SR +V LLLLLLLL VP +ALPP+
Sbjct: 11 SRWEQVAALLLLLLLLGVP-----PRSLALPPI 38
>gi|50658079 tubulin tyrosine ligase-like family, member 5 [Homo
sapiens]
Length = 1281
Score = 26.2 bits (56), Expect = 5.9
Identities = 15/55 (27%), Positives = 24/55 (43%)
Query: 4 RQVSRSPRVRLLLLLLLLLVVPWGVRTASGVALPPVGVLSLRPPGRAWADPATPR 58
RQ S S + LL + L + G+ S + PP + P G W+ + P+
Sbjct: 1043 RQYSPSSHINLLTQQVTNLNLATGIINRSSASAPPTLRPIISPSGPTWSTQSDPQ 1097
>gi|239754297 PREDICTED: hypothetical protein [Homo sapiens]
Length = 175
Score = 25.8 bits (55), Expect = 7.8
Identities = 12/29 (41%), Positives = 14/29 (48%)
Query: 28 VRTASGVALPPVGVLSLRPPGRAWADPAT 56
+ T SG A P + P GR WA P T
Sbjct: 34 LETGSGNARAPPRLSCSAPAGRTWASPET 62
>gi|239752695 PREDICTED: hypothetical protein XP_002345326 [Homo
sapiens]
Length = 1014
Score = 25.8 bits (55), Expect = 7.8
Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 6/63 (9%)
Query: 28 VRTASGVALPPVGVLSLRPPGRAWADPATPRPRRSLALAD------DAAFRERARLLAAL 81
V A P G + + P R + A+P PR LAL D +++F +++ L +
Sbjct: 235 VERGGPAATPSPGAVLDQEPCRVQTNLASPGPRLGLALKDTTGQLVNSSFWQQSNLQSLA 294
Query: 82 ERR 84
RR
Sbjct: 295 RRR 297
>gi|239748836 PREDICTED: hypothetical protein XP_002346833 [Homo
sapiens]
Length = 175
Score = 25.8 bits (55), Expect = 7.8
Identities = 12/29 (41%), Positives = 14/29 (48%)
Query: 28 VRTASGVALPPVGVLSLRPPGRAWADPAT 56
+ T SG A P + P GR WA P T
Sbjct: 34 LETGSGNARAPPRLSCSAPAGRTWASPET 62
>gi|239747673 PREDICTED: doublecortin domain-containing protein
ENSP00000382097-like [Homo sapiens]
Length = 714
Score = 25.8 bits (55), Expect = 7.8
Identities = 10/17 (58%), Positives = 12/17 (70%)
Query: 43 SLRPPGRAWADPATPRP 59
SLRPPG P++PRP
Sbjct: 112 SLRPPGSPVPSPSSPRP 128
>gi|239747229 PREDICTED: hypothetical protein XP_002346943 [Homo
sapiens]
Length = 1014
Score = 25.8 bits (55), Expect = 7.8
Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 6/63 (9%)
Query: 28 VRTASGVALPPVGVLSLRPPGRAWADPATPRPRRSLALAD------DAAFRERARLLAAL 81
V A P G + + P R + A+P PR LAL D +++F +++ L +
Sbjct: 235 VERGGPAATPSPGAVLDQEPCRVQTNLASPGPRLGLALKDTTGQLVNSSFWQQSNLQSLA 294
Query: 82 ERR 84
RR
Sbjct: 295 RRR 297
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.138 0.431
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,103,888
Number of Sequences: 37866
Number of extensions: 188503
Number of successful extensions: 1109
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 1084
Number of HSP's gapped (non-prelim): 43
length of query: 100
length of database: 18,247,518
effective HSP length: 71
effective length of query: 29
effective length of database: 15,559,032
effective search space: 451211928
effective search space used: 451211928
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.