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Search of human proteins with 29826341
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|29826341 calmodulin binding transcription activator 2 [Homo
sapiens]
(1202 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|29826341 calmodulin binding transcription activator 2 [Homo s... 2449 0.0
gi|54112401 calmodulin-binding transcription activator 1 [Homo s... 443 e-124
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 65 5e-10
gi|156119615 myosin IXA [Homo sapiens] 62 3e-09
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 62 3e-09
gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens] 62 3e-09
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 62 3e-09
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 58 5e-08
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 58 5e-08
gi|163965366 nascent polypeptide-associated complex alpha subuni... 58 5e-08
gi|126116596 asp (abnormal spindle)-like, microcephaly associate... 57 8e-08
gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 57 1e-07
gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 57 1e-07
gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ... 57 1e-07
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 55 3e-07
gi|122937321 UNC homeobox [Homo sapiens] 55 4e-07
gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens] 54 9e-07
gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens] 54 9e-07
gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens] 54 9e-07
gi|149158692 HLA-B associated transcript-3 isoform a [Homo sapiens] 54 9e-07
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 54 9e-07
gi|47132519 Ras association and pleckstrin homology domains 1 is... 54 1e-06
gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens] 54 1e-06
gi|18079216 CASK interacting protein 1 [Homo sapiens] 53 2e-06
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 53 2e-06
gi|110832843 TBP-associated factor 4 [Homo sapiens] 52 3e-06
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 52 3e-06
gi|26051278 nuclear pore membrane protein 121 [Homo sapiens] 52 3e-06
gi|18959210 WIRE protein [Homo sapiens] 52 3e-06
gi|188536004 zinc finger protein 469 [Homo sapiens] 52 4e-06
>gi|29826341 calmodulin binding transcription activator 2 [Homo
sapiens]
Length = 1202
Score = 2449 bits (6346), Expect = 0.0
Identities = 1202/1202 (100%), Positives = 1202/1202 (100%)
Query: 1 MNTKDTTEVAENSHHLKIFLPKKLLECLPRCPLLPPERLRWNTNEEIASYLITFEKHDEW 60
MNTKDTTEVAENSHHLKIFLPKKLLECLPRCPLLPPERLRWNTNEEIASYLITFEKHDEW
Sbjct: 1 MNTKDTTEVAENSHHLKIFLPKKLLECLPRCPLLPPERLRWNTNEEIASYLITFEKHDEW 60
Query: 61 LSCAPKTRPQNGSIILYNRKKVKYRKDGYLWKKRKDGKTTREDHMKLKVQGMECLYGCYV 120
LSCAPKTRPQNGSIILYNRKKVKYRKDGYLWKKRKDGKTTREDHMKLKVQGMECLYGCYV
Sbjct: 61 LSCAPKTRPQNGSIILYNRKKVKYRKDGYLWKKRKDGKTTREDHMKLKVQGMECLYGCYV 120
Query: 121 HSSIVPTFHRRCYWLLQNPDIVLVHYLNVPALEDCGKGCSPIFCSISSDRREWLKWSREE 180
HSSIVPTFHRRCYWLLQNPDIVLVHYLNVPALEDCGKGCSPIFCSISSDRREWLKWSREE
Sbjct: 121 HSSIVPTFHRRCYWLLQNPDIVLVHYLNVPALEDCGKGCSPIFCSISSDRREWLKWSREE 180
Query: 181 LLGQLKPMFHGIKWSCGNGTEEFSVEHLVQQILDTHPTKPAPRTHACLCSGGLGSGSLTH 240
LLGQLKPMFHGIKWSCGNGTEEFSVEHLVQQILDTHPTKPAPRTHACLCSGGLGSGSLTH
Sbjct: 181 LLGQLKPMFHGIKWSCGNGTEEFSVEHLVQQILDTHPTKPAPRTHACLCSGGLGSGSLTH 240
Query: 241 KCSSTKHRIISPKVEPRALTLTSIPHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSG 300
KCSSTKHRIISPKVEPRALTLTSIPHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSG
Sbjct: 241 KCSSTKHRIISPKVEPRALTLTSIPHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSG 300
Query: 301 FAEPLEIRPSPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVV 360
FAEPLEIRPSPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVV
Sbjct: 301 FAEPLEIRPSPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVV 360
Query: 361 GTEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALE 420
GTEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALE
Sbjct: 361 GTEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALE 420
Query: 421 PQAAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPPPSPPPSPAPLEPSS 480
PQAAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPPPSPPPSPAPLEPSS
Sbjct: 421 PQAAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPPPSPPPSPAPLEPSS 480
Query: 481 RVGRGEALFGGPVGASELEPFSLSSFPDLMGELISDEAPSIPAPTPQLSPALSTITDFSP 540
RVGRGEALFGGPVGASELEPFSLSSFPDLMGELISDEAPSIPAPTPQLSPALSTITDFSP
Sbjct: 481 RVGRGEALFGGPVGASELEPFSLSSFPDLMGELISDEAPSIPAPTPQLSPALSTITDFSP 540
Query: 541 EWSYPEGGVKVLITGPWTEAAEHYSCVFDHIAVPASLVQPGVLRCYCPAHEVGLVSLQVA 600
EWSYPEGGVKVLITGPWTEAAEHYSCVFDHIAVPASLVQPGVLRCYCPAHEVGLVSLQVA
Sbjct: 541 EWSYPEGGVKVLITGPWTEAAEHYSCVFDHIAVPASLVQPGVLRCYCPAHEVGLVSLQVA 600
Query: 601 GREGPLSASVLFEYRARRFLSLPSTQLDWLSLDDNQFRMSILERLEQMEKRMAEIAAAGQ 660
GREGPLSASVLFEYRARRFLSLPSTQLDWLSLDDNQFRMSILERLEQMEKRMAEIAAAGQ
Sbjct: 601 GREGPLSASVLFEYRARRFLSLPSTQLDWLSLDDNQFRMSILERLEQMEKRMAEIAAAGQ 660
Query: 661 VPCQGPDAPPVQDEGQGPGFEARVVVLVESMIPRSTWKGPERLAHGSPFRGMSLLHLAAA 720
VPCQGPDAPPVQDEGQGPGFEARVVVLVESMIPRSTWKGPERLAHGSPFRGMSLLHLAAA
Sbjct: 661 VPCQGPDAPPVQDEGQGPGFEARVVVLVESMIPRSTWKGPERLAHGSPFRGMSLLHLAAA 720
Query: 721 QGYARLIETLSQWRSVETGSLDLEQEVDPLNVDHFSCTPLMWACALGHLEAAVLLFRWNR 780
QGYARLIETLSQWRSVETGSLDLEQEVDPLNVDHFSCTPLMWACALGHLEAAVLLFRWNR
Sbjct: 721 QGYARLIETLSQWRSVETGSLDLEQEVDPLNVDHFSCTPLMWACALGHLEAAVLLFRWNR 780
Query: 781 QALSIPDSLGRLPLSVAHSRGHVRLARCLEELQRQEPSVEPPFALSPPSSSPDTGLSSVS 840
QALSIPDSLGRLPLSVAHSRGHVRLARCLEELQRQEPSVEPPFALSPPSSSPDTGLSSVS
Sbjct: 781 QALSIPDSLGRLPLSVAHSRGHVRLARCLEELQRQEPSVEPPFALSPPSSSPDTGLSSVS 840
Query: 841 SPSELSDGTFSVTSAYSSAPDGSPPPAPLPASEMTMEDMAPGQLSSGVPEAPLLLMDYEA 900
SPSELSDGTFSVTSAYSSAPDGSPPPAPLPASEMTMEDMAPGQLSSGVPEAPLLLMDYEA
Sbjct: 841 SPSELSDGTFSVTSAYSSAPDGSPPPAPLPASEMTMEDMAPGQLSSGVPEAPLLLMDYEA 900
Query: 901 TNSKGPLSSLPALPPASDDGAAPEDADSPQAVDVIPVDMISLAKQIIEATPERIKREDFV 960
TNSKGPLSSLPALPPASDDGAAPEDADSPQAVDVIPVDMISLAKQIIEATPERIKREDFV
Sbjct: 901 TNSKGPLSSLPALPPASDDGAAPEDADSPQAVDVIPVDMISLAKQIIEATPERIKREDFV 960
Query: 961 GLPEAGASMRERTGAVGLSETMSWLASYLENVDHFPSSTPPSELPFERGRLAVPSAPSWA 1020
GLPEAGASMRERTGAVGLSETMSWLASYLENVDHFPSSTPPSELPFERGRLAVPSAPSWA
Sbjct: 961 GLPEAGASMRERTGAVGLSETMSWLASYLENVDHFPSSTPPSELPFERGRLAVPSAPSWA 1020
Query: 1021 EFLSASTSGKMESDFALLTLSDHEQRELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQR 1080
EFLSASTSGKMESDFALLTLSDHEQRELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQR
Sbjct: 1021 EFLSASTSGKMESDFALLTLSDHEQRELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQR 1080
Query: 1081 CYRKYKQLTWIALKFALYKKMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYRR 1140
CYRKYKQLTWIALKFALYKKMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYRR
Sbjct: 1081 CYRKYKQLTWIALKFALYKKMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYRR 1140
Query: 1141 RPGPPHRTSATLPARNKGSFLTKKQDQAARKIMRFLRRCRHRMRELKQNQELEGLPQPGL 1200
RPGPPHRTSATLPARNKGSFLTKKQDQAARKIMRFLRRCRHRMRELKQNQELEGLPQPGL
Sbjct: 1141 RPGPPHRTSATLPARNKGSFLTKKQDQAARKIMRFLRRCRHRMRELKQNQELEGLPQPGL 1200
Query: 1201 AT 1202
AT
Sbjct: 1201 AT 1202
>gi|54112401 calmodulin-binding transcription activator 1 [Homo
sapiens]
Length = 1673
Score = 443 bits (1140), Expect = e-124
Identities = 201/249 (80%), Positives = 224/249 (89%), Gaps = 3/249 (1%)
Query: 12 NSHHLKIFLPKKLLECLPRCPLLPPERLRWNTNEEIASYLITFEKHDEWLSCAPKTRPQN 71
NS H+KIFLPKKLLECLP+C LP ER RWNTNEEIA+YLITFEKH+EWL+ +PKTRPQN
Sbjct: 45 NSSHVKIFLPKKLLECLPKCSSLPKERHRWNTNEEIAAYLITFEKHEEWLTTSPKTRPQN 104
Query: 72 GSIILYNRKKVKYRKDGYLWKKRKDGKTTREDHMKLKVQGMECLYGCYVHSSIVPTFHRR 131
GS+ILYNRKKVKYRKDGY WKKRKDGKTTREDHMKLKVQG+ECLYGCYVHSSI+PTFHRR
Sbjct: 105 GSMILYNRKKVKYRKDGYCWKKRKDGKTTREDHMKLKVQGVECLYGCYVHSSIIPTFHRR 164
Query: 132 CYWLLQNPDIVLVHYLNVPALEDCGKGCSPIFCSISSDRREWLKWSREELLGQLKPMFHG 191
CYWLLQNPDIVLVHYLNVPA+EDCGK C PI CSI++D++EW KW++EEL+GQLKPMFHG
Sbjct: 165 CYWLLQNPDIVLVHYLNVPAIEDCGKPCGPILCSINTDKKEWAKWTKEELIGQLKPMFHG 224
Query: 192 IKWSCGNGTEE--FSVEHLVQQILDTHPTKPAPRTHACLCSGGLGS-GSLTHKCSSTKHR 248
IKW+C NG FSVE LVQQILD+H TKP PRTH CLC+G LG+ GS+ HKC+S KHR
Sbjct: 225 IKWTCSNGNSSSGFSVEQLVQQILDSHQTKPQPRTHNCLCTGSLGAGGSVHHKCNSAKHR 284
Query: 249 IISPKVEPR 257
IISPKVEPR
Sbjct: 285 IISPKVEPR 293
Score = 388 bits (997), Expect = e-107
Identities = 208/380 (54%), Positives = 253/380 (66%), Gaps = 26/380 (6%)
Query: 527 QLSPALSTITDFSPEWSYPEGGVKVLITGPWTEAAEHYSCVFDHIAVPASLVQPGVLRCY 586
Q S + +TD+SPEWSYPEGGVKVLITGPW EA+ +YSC+FD I+VPASL+QPGVLRCY
Sbjct: 865 QQSGRVFMVTDYSPEWSYPEGGVKVLITGPWQEASNNYSCLFDQISVPASLIQPGVLRCY 924
Query: 587 CPAHEVGLVSLQVAGREGPLSASVLFEYRARRFLSLPSTQLDWLSLDDNQFRMSILERLE 646
CPAH+ GLV+LQVA +S SV+FEY+AR +LPS+Q DWLSLDDNQFRMSILERLE
Sbjct: 925 CPAHDTGLVTLQVAFNNQIISNSVVFEYKARALPTLPSSQHDWLSLDDNQFRMSILERLE 984
Query: 647 QMEKRMAEIAAAGQVPCQGPDAPPVQDEGQGPG----------------FEARVVVLVES 690
QME+RMAE+ + Q G G G FE+RVVV+ E
Sbjct: 985 QMERRMAEMTGSQQHKQASGGGSSGGGSGSGNGGSQAQCASGTGALGSCFESRVVVVCEK 1044
Query: 691 MIPRSTWKGPERLAHGSPFRGMSLLHLAAAQGYARLIETLSQWRSVETGSLDLEQEVDPL 750
M+ R+ W + L H FRGM+LLHLAAAQGYA LI+TL +WR+ S+DLE EVDPL
Sbjct: 1045 MMSRACWAKSKHLIHSKTFRGMTLLHLAAAQGYATLIQTLIKWRTKHADSIDLELEVDPL 1104
Query: 751 NVDHFSCTPLMWACALGHLEAAVLLFRWNRQALSIPDSLGRLPLSVAHSRGHVRLARCLE 810
NVDHFSCTPLMWACALGHLEAAV+L++W+R+A+SIPDSLGRLPL +A SRGHV+LA CLE
Sbjct: 1105 NVDHFSCTPLMWACALGHLEAAVVLYKWDRRAISIPDSLGRLPLGIARSRGHVKLAECLE 1164
Query: 811 ELQRQEPSV--EPPFALSPPSSSPDT-------GLSSVSSPSELSDGTFSVTSAYSSAPD 861
LQR E + + P P S P T ++SSP E+ G + S
Sbjct: 1165 HLQRDEQAQLGQNPRIHCPASEEPSTESWMAQWHSEAISSP-EIPKGVTVIASTNPELRR 1223
Query: 862 GSPPPAPLPASEMTMEDMAP 881
P+ +SE + AP
Sbjct: 1224 PRSEPSNYYSSESHKDYPAP 1243
Score = 305 bits (780), Expect = 2e-82
Identities = 198/415 (47%), Positives = 249/415 (60%), Gaps = 65/415 (15%)
Query: 806 ARCLEE--LQRQEPSVEPPFALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPDGS 863
A LEE +++Q PS + P + SP G+ S + A S P G
Sbjct: 1264 ALSLEEPNIRKQSPSSKQSV---PETLSPSEGVRDFSRELSPPTPETAAFQASGSQPVGK 1320
Query: 864 PPPAPL------------PASEMTMEDMAPGQLSSGVPEAPLLLMDYEATNSKGPLSSLP 911
L P ++ AP Q+ P + L++ + E N++ L S
Sbjct: 1321 WNSKDLYIGVSTVQVTGNPKGTSVGKEAAPSQVRPREPMSVLMMANREVVNTE--LGSYR 1378
Query: 912 ALPPASDDGAAPEDADSPQAVDVIPVDMISLAKQIIEATPERIKREDFVGLPEAGASMRE 971
D A E+ P +D I V+M++LA+ IIEATP+RIK+E+FV + +G E
Sbjct: 1379 -------DSAENEECGQP--MDDIQVNMMTLAEHIIEATPDRIKQENFVPMESSGL---E 1426
Query: 972 RTGAVGLSETMSWLASYLENVDHFPSS-----------------------TPPSELPFER 1008
RT +S TMSWLASYL + D PS+ +P SE+ FE+
Sbjct: 1427 RTDPATISSTMSWLASYLADADCLPSAAQIRSAYNEPLTPSSNTSLSPVGSPVSEIAFEK 1486
Query: 1009 GRLAVPSAPSWAEFLSASTSGKMESDFALLTLSDHEQRELYEAARVIQTAFRKYKGRRLK 1068
L PSA W+EFLSASTS K+E++FA LTLSDHEQRELYEAAR++QTAFRKYKGR L+
Sbjct: 1487 PNL--PSAADWSEFLSASTSEKVENEFAQLTLSDHEQRELYEAARLVQTAFRKYKGRPLR 1544
Query: 1069 EQQEVAAAVIQRCYRKYKQLTWIALKFALYKKMTQAAILIQSKFRSYYEQKRFQQSRRAA 1128
EQQEVAAAVIQRCYRKYKQ +ALYKKMTQAAILIQSKFRSYYEQK+FQQSRRAA
Sbjct: 1545 EQQEVAAAVIQRCYRKYKQ-------YALYKKMTQAAILIQSKFRSYYEQKKFQQSRRAA 1597
Query: 1129 VLIQQHYRSYRR--RPGPPHRTSATLPARNKGSFLTKKQDQAARKIMRFLRRCRH 1181
VLIQ++YRSY++ + RT+ + + + S LTKKQDQAARKIMRFLRRCRH
Sbjct: 1598 VLIQKYYRSYKKCGKRRQARRTAVIVQQKLRSSLLTKKQDQAARKIMRFLRRCRH 1652
Score = 42.4 bits (98), Expect = 0.003
Identities = 18/35 (51%), Positives = 25/35 (71%), Gaps = 1/35 (2%)
Query: 375 FDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTP 409
FDPD FLN+P++GQTYGGG G+ + + H+P
Sbjct: 483 FDPDCFLNNPKQGQTYGGG-GLKAEMVSSNIRHSP 516
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 64.7 bits (156), Expect = 5e-10
Identities = 102/358 (28%), Positives = 138/358 (38%), Gaps = 57/358 (15%)
Query: 215 THPTKPAPRTHACLCS----GGLGSGSLTHKCSSTKHRIISPKVEPRALTLTSIPHAHPP 270
T P+ AP + L S LGS +L ++ +SP+ +LT S P + PP
Sbjct: 396 TSPSLQAPPSPLALSSLQATTSLGSPTLQ---ATHSFLTMSPRQTQASLTSPSRPASTPP 452
Query: 271 EPPPLIAPLP-PELPKAHTSPSSSSSSSSSGFAEPLEIRPSPPTS--RGGSSRGGTAILL 327
+ PPL APL P P TS S + S SS PL I P S S + + L+
Sbjct: 453 DSPPLQAPLSLPASPPLQTSLSPAVSPLSS----PLTIHPLQALSSLASHSPQAPLSSLI 508
Query: 328 LTGLEQRAGGLTPTRHLAPQADPRPSM----SLAVVVGTEPSAP------PAPPSPAFDP 377
+ LE ++ P+ P + P + SLA SAP PP PA P
Sbjct: 509 MPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP 568
Query: 378 DRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPPPQSVAGGR 437
L +P T P+ P + A TP PA A P PP +A
Sbjct: 569 ---LQAPPSPLT-----TPPPETPSSIA--TPPPQAPPALASPPLQGLPSPPLSPLA--- 615
Query: 438 RGNCFFIQDDDSGEELKGHGAAPPI---PSPPPSPPPS----PAPLEPSS-RVGRGEALF 489
+ A PP+ PSPP SPP S P+P P++ V +A F
Sbjct: 616 ----------TPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 665
Query: 490 GGPVGASELEPFSLSSFPDLMGELI--SDEAPSIPAPTPQLSPALSTITDFSPEWSYP 545
P PFS + P + S PS+ AP Q+ P+ SP + P
Sbjct: 666 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP 723
Score = 58.2 bits (139), Expect = 5e-08
Identities = 173/770 (22%), Positives = 248/770 (32%), Gaps = 114/770 (14%)
Query: 217 PTKPAPRTHACL----CSGGLGSGSLTHKCSSTKHRIISPKVEPRALTLTSIPHA--HPP 270
P P P T A L +G +G L + I P+ PRA S + +P
Sbjct: 33 PRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI-PESAPRAGPTRSAGTSSRNPA 91
Query: 271 EPPPLIAPLPPELPKAHTSPSS-SSSSSSSGFAEP-------LEIRPSPPTSRGGSSRGG 322
PP P +TSP SS +SG P L I +RG ++
Sbjct: 92 SRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAP 151
Query: 323 TAILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVVGTEPSAPPAPPSPAFD-PDRFL 381
L G + G TP A R S + VG AP A P P + P + +
Sbjct: 152 KRSALSAGARRDTSGPTPGTPSPAMA--RRSRAAGTEVGLPRPAPSARPRPPTEGPRKSV 209
Query: 382 NSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPPPQSVAGGRRGNC 441
+S T P S ++A + AR P S G R
Sbjct: 210 SSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP--SARGTPRAPA 267
Query: 442 FFIQDDDSG-EELKGHGAAPPIPSPPPSPPP-SPAPLEPSSRVGRGEALFGGPVGASELE 499
Q G + L+ PP P+ P S +PL S G P A+
Sbjct: 268 HPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPL 327
Query: 500 PFSLSSFPDLMGELISDEAPSIPAPTPQLSPALSTITDFSPEWSYPEGGVKVLITGPWTE 559
P +L P L L P P P+P P+L T+ SP + P + T P
Sbjct: 328 PATLPPSPPLATPL-----PLAP-PSPSAPPSLQTLP--SPPATPPSQAPPSMTTPPMQA 379
Query: 560 AAEHYSCVFDHIAVPASLVQPGVLRCYCPAHEVGLVSLQVAGREGPLSASVLFEYRARRF 619
+ I VP SL P + + P S L +A
Sbjct: 380 PPSLQT--IPPIQVPHSLTSPSL--------------------QAPPSPLALSSLQATTS 417
Query: 620 LSLPSTQL--DWLSLDDNQFRMSILERLEQMEKRMAEIAAAGQVPCQGPDAPPVQDEGQG 677
L P+ Q +L++ Q + A + + + PD+PP+Q
Sbjct: 418 LGSPTLQATHSFLTMSPRQTQ--------------ASLTSPSRPASTPPDSPPLQAPLSL 463
Query: 678 PGFEARVVVLVESMIPRST------WKGPERLAHGSPFRGMSLLHLAAAQGYARLIETLS 731
P L ++ P S+ + LA SP +S L + + + L
Sbjct: 464 PASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523
Query: 732 QW--RSVETGSLD---------LEQEVDPLNVDHFSCTPLMWACALGHLEAAVLLFRWNR 780
Q S+ T L+ L+ PL H P C L + L
Sbjct: 524 QTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPL-QAPPSPLTTPPPE 582
Query: 781 QALSIPDSLGRLPLSVAHSRGHVRLARCLEELQRQEPSVEPPFAL----SPPSSSPDTGL 836
SI + P ++A + L L P P AL +PPS L
Sbjct: 583 TPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPL 642
Query: 837 SSVSSPSELSDGTFSV---TSAYSSAPDG------SPPPAPLPASEMTMEDMAPGQLSSG 887
S +++PS + +V + +S P SPP +P + T AP L++
Sbjct: 643 SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 702
Query: 888 VPEAPLLLMDYEATNSKGPLSSLPALPPASDDGAAPEDADSPQAVDVIPV 937
+ P S PA PP S P A P A + V
Sbjct: 703 PLQVP---------------PSPPASPPMSPSATPPPQAPPPLAAPPLQV 737
Score = 56.6 bits (135), Expect = 1e-07
Identities = 85/299 (28%), Positives = 109/299 (36%), Gaps = 56/299 (18%)
Query: 251 SPKVEPRALTLTSIPHA----------HPPEPPPLIAPL-PPELPKAHTSPSSSSSSSSS 299
SP + P A P+A PP PP+ AP PP P S + S + S
Sbjct: 639 SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS 698
Query: 300 GFAEPLEIRPSPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVV 359
A PL++ PSPP S ++P+ PQA P + V
Sbjct: 699 LAAPPLQVPPSPPAS---------------------PPMSPSATPPPQAPPPLAAPPLQV 737
Query: 360 VGTEPSAPPAPPSPAFDPDR---FLNSP--QRGQTYGGGQGVSPDFPEAEAAHTPCSALE 414
+ P++PP PS A P R L +P Q + +SP + P A
Sbjct: 738 PPSPPASPPMSPS-ATPPPRVPPLLAAPPLQVPPSPPASLPMSP-LAKPPPQAPPALATP 795
Query: 415 PAAAL-EPQAAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPI---PSPPPSP- 469
P AL P A+ G P S + + + L AAP + PSPP SP
Sbjct: 796 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL----AAPLLQVPPSPPASPT 851
Query: 470 ------PPSPAPLEPSSRVGRGEALFGGPVGASELEPFSLSSFPDLMGELISDEAPSIP 522
PP+P P S AL GP P S S PDL G S A S P
Sbjct: 852 LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGH--SSSATSTP 908
Score = 50.1 bits (118), Expect = 1e-05
Identities = 76/278 (27%), Positives = 97/278 (34%), Gaps = 58/278 (20%)
Query: 252 PKVEPRALTLTSIPHAHPPEPPPLIAPLPPELP--------KAHTSPSSSSSSSSSGFAE 303
P P +L ++ + P PP L P LP +A SPS+S S
Sbjct: 769 PPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 828
Query: 304 P----------LEIRPSPPTSRG--GSSRGGTAILLLTGLEQRAGGLTPTRHLAPQADPR 351
P L++ PSPP S R T G + G T LAP P
Sbjct: 829 PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP-----GPDTSVSGPRLTLALAPGPPPP 883
Query: 352 PSMSLAVVVGTEPSAPPAPPSPAFDPDRFLNSPQ--RGQTYG--GGQGVSPDFPEAE--A 405
PS S PS+ + P A ++P+ RG G GG SP P+AE A
Sbjct: 884 PSRS--------PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP-PDAELAA 934
Query: 406 AHTPCSALEPAAALEPQAAARGP---PPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPI 462
H + PA L + A P PP + G G C + + GA P
Sbjct: 935 CHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPG 994
Query: 463 PSPPPSPPPSPAPLEPSSRVGRGEALFGGPVGASELEP 500
PSP S G+A G GAS P
Sbjct: 995 PSPGTS---------------GGKAAAGAGAGASSRSP 1017
Score = 39.3 bits (90), Expect = 0.023
Identities = 58/247 (23%), Positives = 97/247 (39%), Gaps = 24/247 (9%)
Query: 799 SRGHVRLARCLEELQRQEPSVE-PPFALSPPSSSPDTGLSSVSSPSELSDGTFSVTSA-- 855
SR A L R PS P A + PS GL ++ P + +
Sbjct: 239 SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP 298
Query: 856 YSSAPDGSPPPAPLPASEMTMEDMAPGQLSSGVPEAPLLL----MDYEATNSKGPLSSLP 911
SS+P +P P+ A + D A L + +P +P L + + ++ L +LP
Sbjct: 299 LSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLP 358
Query: 912 ALPPASDDGAAPED-----ADSPQAVDVIPVDMI--SLAKQIIEATPERIKREDFVGLPE 964
+ PPA+ AP +P ++ IP + SL ++A P +
Sbjct: 359 S-PPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTS 417
Query: 965 AGASMRERTGA---VGLSETMSWLASYLENVDHFPSSTPPSELPFERGRLAVPSAPSWAE 1021
G+ + T + + +T + L S P+STPP P + L++P++P
Sbjct: 418 LGSPTLQATHSFLTMSPRQTQASLTS-----PSRPASTPPDSPPLQ-APLSLPASPPLQT 471
Query: 1022 FLSASTS 1028
LS + S
Sbjct: 472 SLSPAVS 478
Score = 36.2 bits (82), Expect = 0.19
Identities = 30/114 (26%), Positives = 43/114 (37%), Gaps = 7/114 (6%)
Query: 817 PSVEPPFALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPDGSPPPAPLPASEMTM 876
P PP +PP P S P+ L + + +PP LP+ +
Sbjct: 754 PPRVPPLLAAPPLQVPP------SPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASF 807
Query: 877 EDMAPGQLSSGVPEAPLLLMDYEATN-SKGPLSSLPALPPASDDGAAPEDADSP 929
AP S+ +P +PL +A PL +P PPAS AP +P
Sbjct: 808 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 861
Score = 35.0 bits (79), Expect = 0.43
Identities = 34/107 (31%), Positives = 42/107 (39%), Gaps = 18/107 (16%)
Query: 817 PSVEPPFALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPDGSPPPAPLPASEMTM 876
P PP A P P S SP S T P + PP +P S
Sbjct: 724 PQAPPPLAAPPLQVPPSPPASPPMSP--------SATPPPRVPPLLAAPPLQVPPSPPAS 775
Query: 877 EDMAPGQLSSGVPEAPLLLMDYEATNSKGPLSSLPALPPASDDGAAP 923
M+P L+ P+AP L + PL +LP+ PPAS G AP
Sbjct: 776 LPMSP--LAKPPPQAPPAL-------ATPPLQALPS-PPASFPGQAP 812
Score = 33.1 bits (74), Expect = 1.6
Identities = 32/106 (30%), Positives = 45/106 (42%), Gaps = 21/106 (19%)
Query: 817 PSVEPPFALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPDGSPPPAPLPASEMTM 876
P+++ P PP+ PDT SVS P + AP PPP+ P+S ++
Sbjct: 850 PTLQAP--RRPPTPGPDT---SVSGPR----------LTLALAPGPPPPPSRSPSSTLSG 894
Query: 877 EDMAPGQLSSGVPEAPLLLMDYEATNSKGPLSSLPALPPASDDGAA 922
D+A SS P L Y++ GP A PP + AA
Sbjct: 895 PDLAGH--SSSATSTPEELRGYDS----GPEGGAAASPPPDAELAA 934
>gi|156119615 myosin IXA [Homo sapiens]
Length = 2548
Score = 62.4 bits (150), Expect = 3e-09
Identities = 50/169 (29%), Positives = 85/169 (50%), Gaps = 12/169 (7%)
Query: 1040 LSDHEQRELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKY---KQLTWIALKFA 1096
L D +E+ ++Q FR R+ A+ +IQR +R Y KQ+ A++
Sbjct: 1011 LQDLLHQEVLRRIILLQRWFRVLLCRQHFLHLRQASVIIQRFWRNYLNQKQVRDAAVQKD 1070
Query: 1097 LYKKMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYRRRPGPPHRTSATLPARN 1156
+ M AA L+Q+ +R++ E++R+ + R AA++IQQ +R Y RR H + + AR
Sbjct: 1071 AFV-MASAAALLQASWRAHLERQRYLELRAAAIVIQQKWRDYYRR---RHMAAICIQARW 1126
Query: 1157 KGSFLTKKQDQAARKIMRFLRRC-----RHRMRELKQNQELEGLPQPGL 1200
K +K+ + +KI+ C R R + LK+ + E P+ GL
Sbjct: 1127 KAYRESKRYQEQRKKIILLQSTCRGFRARQRFKALKEQRLRETKPEVGL 1175
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 62.4 bits (150), Expect = 3e-09
Identities = 68/255 (26%), Positives = 84/255 (32%), Gaps = 35/255 (13%)
Query: 251 SPKVEPRALTLTSIPHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLEIRPS 310
+P P A + P HPP P P + +P P P S+ S RP
Sbjct: 649 APVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSA-------RPG 701
Query: 311 PPTSRG--GSSRGGTAIL---LLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVVG---T 362
PPT+ G S G + LL G E G LAP P P++ G
Sbjct: 702 PPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSGTPPPTIPPDETFGGRVP 761
Query: 363 EPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQ 422
P+ A D + L S +G+ P P + TP P
Sbjct: 762 RPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATP-----------PP 810
Query: 423 AAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPPPSPPPSPAPLEPSSRV 482
A GPP S + + EEL P P PPP P P P L P V
Sbjct: 811 IAPTGPPTASPP---------VPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLV 861
Query: 483 GRGEALFGGPVGASE 497
G GGP E
Sbjct: 862 PEGTPGGGGPPALEE 876
Score = 34.3 bits (77), Expect = 0.73
Identities = 32/112 (28%), Positives = 41/112 (36%), Gaps = 12/112 (10%)
Query: 816 EPSVEPPFALSPPSSSPDTGLSS-VSSPS-------ELSDGTFSVTSAYSSA----PDGS 863
E + P PP+ PD V P+ E SD S+ S + P+G
Sbjct: 736 EDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGL 795
Query: 864 PPPAPLPASEMTMEDMAPGQLSSGVPEAPLLLMDYEATNSKGPLSSLPALPP 915
PP P P S T +AP + P P E + GPL P PP
Sbjct: 796 PPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPP 847
Score = 31.2 bits (69), Expect = 6.2
Identities = 32/117 (27%), Positives = 45/117 (38%), Gaps = 14/117 (11%)
Query: 817 PSVEPPFALSPPSSSPDTGLSS---VSSPSELSDGTFSVTSAYSS----APDGSPPPAPL 869
PS P PP+++ GLS VS P L G + + + AP G+PPP
Sbjct: 696 PSARP----GPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSGTPPPTIP 751
Query: 870 PASEMTMEDMAPGQLSSGVPEAPLLLMDYEATNSKGPL---SSLPALPPASDDGAAP 923
P P + EA + + E+ + + LP LPP GA P
Sbjct: 752 PDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATP 808
>gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]
Length = 1488
Score = 62.4 bits (150), Expect = 3e-09
Identities = 85/301 (28%), Positives = 101/301 (33%), Gaps = 75/301 (24%)
Query: 265 PHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAE-----PLEIRPSPPTSRG--- 316
PH P PPP P PPE K+ S+SSS S F P ++ P PPT +
Sbjct: 1176 PHQRMPPPPP---PPPPEEYKSQRPVSNSSSFLGSLFGSKRGKGPFQM-PPPPTGQASAS 1231
Query: 317 ----------------GSSRGGTAIL--------LLTGLEQRAGGLTPTRHLAPQA---- 348
G S GG +L L + G P +L PQ
Sbjct: 1232 SSSASSTHHHHHHHHHGHSHGGLGVLPDGQSKLQALHAQYCQGPGPAPPPYLPPQQPSLP 1291
Query: 349 ----DPRPSMSLAVVVGTEPSAPPAPPSPAFDPDRFLNSPQR------GQTYGGGQGVSP 398
P P L + SAPP P F + PQ G+ G G P
Sbjct: 1292 PPPQQPPPLPQLGSIPPPPASAPPVGPHRHFHAHGPVPGPQHYTLGRPGRAPRRGAGGHP 1351
Query: 399 DFPE--AEAAHTPCSALE--PAAALEPQAAARGP------------PPQSVAGG---RRG 439
F H P S L A P A +GP P AGG R
Sbjct: 1352 QFAPHGRHPLHQPTSPLPLYSPAPQHPPAHKQGPKHFIFSHHPQMMPAAGAAGGPGSRPP 1411
Query: 440 NCFFIQDDDSGEELKGHGAAPPIPSPPPSPPPSP----APLEPSSRVGRGEALFGGPVGA 495
+ L H PP PS PP PPPSP +PL P+S G A GP G
Sbjct: 1412 GGSYSHPHHPQSPLSPHSPIPPHPSYPPLPPPSPHTPHSPLPPTSPHGPLHA--SGPPGT 1469
Query: 496 S 496
+
Sbjct: 1470 A 1470
Score = 35.4 bits (80), Expect = 0.33
Identities = 67/286 (23%), Positives = 91/286 (31%), Gaps = 53/286 (18%)
Query: 229 CSGGL-GSGSLTHKCSSTKHRI------ISPKVEPRALTLTSIPHAHPPEPPPLIAPLPP 281
C GG+ G GS + I S +V+ A ++ + HP P P
Sbjct: 436 CGGGIDGGGSSVTTSGEFSNDITELEDSFSKQVKSLAESIDEALNCHPSGPMSE-EPGSA 494
Query: 282 ELPKAHTSPSSSSSSSSSGFAEPLEIRPSPPTSRGGSSRGGTAILLLTGLEQRAGGLTPT 341
+L K + SS++S PL + + P Q++ P+
Sbjct: 495 QLEKRESKEQQEDSSATSFSDLPLYLDDTVP--------------------QQSPERLPS 534
Query: 342 RHLAPQADPRPSMSLAVVVGTEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFP 401
PQ P PP PP P R S + G G G DF
Sbjct: 535 TEPPPQGRPE--------FWAPAPLPPVPP-PVPSGTREDGSREEGTRRGPGCLECRDF- 584
Query: 402 EAEAAHTPCSALEPAAALEPQAAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGH----G 457
AAH P +EP P ++ +S G + D S H G
Sbjct: 585 RLRAAHLPLLTIEP-----PSDSSVDLSDRSDRGSVHRQLVYEADGCSPHGTLKHKGPPG 639
Query: 458 AAP------PIPSPPPSPPPSPAPLEPSSRVGRGEALFGGPVGASE 497
AP P P P PP P P P+S G G +G E
Sbjct: 640 RAPIPHRHYPAPEGPAPAPPGPLPPAPNSGTGPSGVAGGRRLGKCE 685
Score = 34.7 bits (78), Expect = 0.56
Identities = 59/227 (25%), Positives = 71/227 (31%), Gaps = 29/227 (12%)
Query: 270 PEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLEIRPSPPTSRG--GSSRGGTAILL 327
P PPP + P P LP P S P PP S G R A
Sbjct: 1277 PAPPPYLPPQQPSLPPPPQQPPPLPQLGSI---------PPPPASAPPVGPHRHFHAHGP 1327
Query: 328 LTGLEQRA---GGLTPTRHLA--PQADPRPSMSLAVVVGTEP---SAPPAPPSPAFDPDR 379
+ G + G P R PQ P L P AP PP+ P
Sbjct: 1328 VPGPQHYTLGRPGRAPRRGAGGHPQFAPHGRHPLHQPTSPLPLYSPAPQHPPAHKQGPKH 1387
Query: 380 FLNS--PQRGQTYG--GGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPPPQSVAG 435
F+ S PQ G GG G P H P S L P + + P + PP S
Sbjct: 1388 FIFSHHPQMMPAAGAAGGPGSRPPGGSYSHPHHPQSPLSPHSPIPPHPSYPPLPPPSPHT 1447
Query: 436 GRRGNCFFIQDDDSGEELKGHGAAPPIPSPPPSPPPSPAPLEPSSRV 482
+ H + PP + PPS P P S+ V
Sbjct: 1448 PHSPL------PPTSPHGPLHASGPPGTANPPSANPKAKPSRISTVV 1488
>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
Length = 2161
Score = 62.0 bits (149), Expect = 3e-09
Identities = 88/310 (28%), Positives = 109/310 (35%), Gaps = 65/310 (20%)
Query: 265 PHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLEI-----RPSPPTSRGGSS 319
P PPEPP P+P + SP + SG P PSPP +R GS
Sbjct: 924 PTTSPPEPPYSTPPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSR 983
Query: 320 RGGTAILLLTGLEQRAGGLTPTRHLAPQ------ADPRPSMSLAVVVGTEPSAPPAPP-- 371
+G L P H P P+P A PP PP
Sbjct: 984 EKSL---------YHSGPLPPAHHHPPHHHHHHAPPPQPHHHHA--------HPPHPPEM 1026
Query: 372 ----SPAFDPDRFLNSPQ---RGQTYGGGQGVSPDFP----EAEAAHTPCSALEPAA--- 417
SP P R PQ RG GGG +P P A S+ PA
Sbjct: 1027 ETGGSPDDPPPRLALGPQPSLRGWR-GGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYF 1085
Query: 418 ALEPQAAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSP--PPSPPPSPAP 475
L P+AA+ + +G R Q GE KG G PP PSP P SP P PA
Sbjct: 1086 QLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKG-GGLPPAPSPTSPASPQPPPAV 1144
Query: 476 LEPSSRVGRGEALFGGPVGASELE-PFSLSSFPDLMGELISDEAPSIPAPT--------- 525
PS + P+ ++ P + SS G E P+ P PT
Sbjct: 1145 AAPSEKNSI-------PIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSS 1197
Query: 526 PQLSPALSTI 535
P +PA+S +
Sbjct: 1198 PSPAPAMSPV 1207
Score = 45.8 bits (107), Expect = 2e-04
Identities = 61/232 (26%), Positives = 77/232 (33%), Gaps = 45/232 (19%)
Query: 266 HAHPPEPPPLIAPLPPE--LPKAHTSPSSSSSSSSSGFAEPLEIRPSPPTSRGGSSRGGT 323
HAHPP PP + P+ P+ P S G P PSP S GS+ GG
Sbjct: 1017 HAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSP--SHHGSAGGG- 1073
Query: 324 AILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVVGTEPSAPPAPPSPAFDPDRFLNS 383
GG + L P + S A+ V P +
Sbjct: 1074 ------------GGSSQGPALRYFQLPPRAASAAMYVPARSGR--GRKGPLVKQTKVEGE 1119
Query: 384 PQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGP-------PPQSVAGG 436
PQ+G GG P A + +P S P A P P P + + G
Sbjct: 1120 PQKG----GG------LPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSG 1169
Query: 437 R--RGNCFFIQDDDSGEELKGHGAAPPIPSP-------PPSPPPSPAPLEPS 479
R +G+ + E G G PSP PPSP P P P PS
Sbjct: 1170 RSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPASPS 1221
Score = 39.7 bits (91), Expect = 0.017
Identities = 55/238 (23%), Positives = 69/238 (28%), Gaps = 57/238 (23%)
Query: 268 HPPEPPPL-----IAPLPPELPKAHTSPSSSSSSSSSGFAEPLEIRPSPPTSRGGSSRGG 322
HPP PP AP P P T S S PLE S T S+ GG
Sbjct: 1646 HPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGG 1705
Query: 323 TAILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVVGTEPSAPPAPPSPAFDPDRFLN 382
G GG + P + + + + P P + P
Sbjct: 1706 -------GSAGGGGG----AGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTP 1754
Query: 383 SPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAA--------LEPQAAARGPPPQSVA 434
S RG+ G G+ P + P + P + L A GPP VA
Sbjct: 1755 SKLRGRALGASGGLRPG--PSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVA 1812
Query: 435 GGRRGNCFFIQDDDSGEELKGHGAAPPIP----------------SPPPSPPPSPAPL 476
GG + PP+P P P PPP P PL
Sbjct: 1813 GG---------------PVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPL 1855
Score = 39.3 bits (90), Expect = 0.023
Identities = 71/299 (23%), Positives = 96/299 (32%), Gaps = 57/299 (19%)
Query: 269 PPEPPPLIAPLPPELPKAHT-----------------SPSSSSSSSSSGFAEPLEIRP-S 310
PP PP PP P H+ P+ +G + P S
Sbjct: 1377 PPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPAS 1436
Query: 311 PPTSRGG-------SSRGGTAILLLTGLEQRA---GGLTPTRHLAPQADPRPSMSLAVVV 360
PP +R ++ G +LL G E A G P R AP+ R + + +
Sbjct: 1437 PPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLE 1496
Query: 361 GTEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALE 420
+P AP + RG G GV P P +P S P A+ E
Sbjct: 1497 NCQPRAPV--------------TSGRGPPSEDGPGVPPPSPRRSVPPSPTS---PRASEE 1539
Query: 421 ---PQAAARGPPPQSVAGGRRGNCFFIQDDDSGEELKG---HGAAPPIPSPPPSPPPSPA 474
P PPP G F++ E +P P PP P +PA
Sbjct: 1540 NGLPLLVL--PPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPA 1597
Query: 475 PLEPSSRVGRGEALFGGPVGASELEPFSLSSFPDLMGELI--SDEAPSIPAPTPQLSPA 531
P P V P S SL+S+ + L + AP P P +PA
Sbjct: 1598 PATPLPPVPPPAVAAAPPTLDSTAS--SLTSYDSEVATLTQGASAAPGDPHPPGPPAPA 1654
Score = 39.3 bits (90), Expect = 0.023
Identities = 77/353 (21%), Positives = 104/353 (29%), Gaps = 80/353 (22%)
Query: 250 ISPKVEPRAL-TLTSIPHA-----------HPPEPPPLIAPLPPELPKAHTSPSSSSSSS 297
+ P+V P L T +S+P PP P PL P L S S SS
Sbjct: 1818 VEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLAQPQASALATVKASIISELSSK 1877
Query: 298 SSGFAEPLEIRPSPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLA 357
F + P +RGGS GG + P R + Q S +
Sbjct: 1878 LQQFGGSSAAGGALPWARGGSGGGGDS-------HHGGASYVPERTSSLQRQRLSDDSQS 1930
Query: 358 VVVGTEPSA-------PPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPC 410
++ S+ PP PP P G GVSP A A +P
Sbjct: 1931 SLLSKPVSSLFQNWPKPPLPPLPT------------------GTGVSPTAAAAPGATSPS 1972
Query: 411 SALEPAAA---------LEPQAAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPP 461
++ + + P R P P + P
Sbjct: 1973 ASSSSTSTRHLQGVEFEMRPPLLRRAPSPSLLPASEH-------------------KVSP 2013
Query: 462 IPSPPPSPPPSPAPLEPSSRVGRGEALFGGPVGASELEPFSLSSFPDLMGELISDEAPSI 521
P P P PL P RG G A P + P + G L ++
Sbjct: 2014 APRPSSLPILPSGPLYPGLFDIRGSPTGGAGGSADPFAPVFVPPHPGISGGL----GGAL 2069
Query: 522 PAPTPQLSPA-LSTITDFSPEWSYPEGGVKVLITGPWTE---AAEHYSCVFDH 570
+ LSP L ++ P + P G W E AEH + DH
Sbjct: 2070 SGASRSLSPTRLLSLPPDKPFGAKPLGFWTKFDVADWLEWLGLAEHRAQFLDH 2122
Score = 38.5 bits (88), Expect = 0.039
Identities = 85/364 (23%), Positives = 113/364 (31%), Gaps = 107/364 (29%)
Query: 270 PEPPPLIA--------PLPPELPKA-HTSPSSSSSSSSSGFAEPLEIRPSPPTSRGGSSR 320
P+PPP +A P+P + KA TS S SS SS AEP P+ P GG
Sbjct: 1138 PQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEP----PTQPEPTGGGGG 1193
Query: 321 GGTAI-----------------------------------LLLTGLEQRAGGLTPTRHLA 345
GG++ L G +R GG
Sbjct: 1194 GGSSPSPAPAMSPVPPSPSPVPTPASPSGPATLDFTSQFGAALVGAARREGGWQN----- 1248
Query: 346 PQADPRPSMSLAVVVGTEPS--------APPAPP---SPAFDPDRF-------LNSPQRG 387
+A R ++ L+ G E A P P S + D F L S G
Sbjct: 1249 -EARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSG 1307
Query: 388 QTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPPPQSVAGGRRGNCFFIQDD 447
YGG S + + S L P + P P + G ++
Sbjct: 1308 AGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPASPL-----GLALAARER 1362
Query: 448 DSGEELKGHGAAPPIP--------SPPPSP-------------------PPSPAPLEPSS 480
E +G GA P P +PPP+P PP PA E
Sbjct: 1363 ALKESSEGGGAPQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGY 1422
Query: 481 RVGRG---EALFGGPVGASELEPFSLSSFPDLMGELISDEAPSIPAPTPQLSPALSTITD 537
R G G ++L P A L +G L+ PAP P +S +
Sbjct: 1423 RAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAP 1482
Query: 538 FSPE 541
PE
Sbjct: 1483 EEPE 1486
Score = 37.0 bits (84), Expect = 0.11
Identities = 52/209 (24%), Positives = 65/209 (31%), Gaps = 59/209 (28%)
Query: 272 PPPLIAP-LPPELPKAHTSPSSSSSSSSSGFAEPLEIRPSPPTSRGGSSRGGTAILLLTG 330
PP P +PP P+ PS +S +S PL + P P
Sbjct: 1510 PPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPP------------------- 1550
Query: 331 LEQRAGGLTPTRHLAPQADPRPSMSLAVVVGTEPSAPPAPPSPAFDPDRFLNSPQRGQTY 390
AP D L V EP PP S +F+ +P
Sbjct: 1551 --------------APSVDVEDGEFLFV----EPLPPPLEFSNSFEKPESPLTP------ 1586
Query: 391 GGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPPPQSVAGGRRGNCFFIQDDDSG 450
G P+ A TP + P P AA P S A D +
Sbjct: 1587 ----GPPHPLPDTPAPATPLPPVPP-----PAVAAAPPTLDSTASSLTS-----YDSEVA 1632
Query: 451 EELKGHGAAPPIPSPP-PSPPPSPAPLEP 478
+G AAP P PP P P +PAP P
Sbjct: 1633 TLTQGASAAPGDPHPPGPPAPAAPAPAAP 1661
Score = 36.2 bits (82), Expect = 0.19
Identities = 39/129 (30%), Positives = 51/129 (39%), Gaps = 17/129 (13%)
Query: 817 PSVEPPFALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPDGSPPP------APLP 870
P V PP + P + T S S SE++ ++T S+AP PP AP P
Sbjct: 1603 PPVPPPAVAAAPPTLDSTASSLTSYDSEVA----TLTQGASAAPGDPHPPGPPAPAAPAP 1658
Query: 871 ASEMTMEDMAPGQLSSGVPEAPLLLMD---YEATNSKGPLSSLPALPPAS---DDGAAPE 924
A+ D PG SG+ E E +S LSSL A S GA
Sbjct: 1659 AAPQPGPDPPPG-TDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAG 1717
Query: 925 DADSPQAVD 933
A P+ +D
Sbjct: 1718 VASGPELLD 1726
Score = 32.7 bits (73), Expect = 2.1
Identities = 60/233 (25%), Positives = 72/233 (30%), Gaps = 60/233 (25%)
Query: 265 PHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLEIRPSPPTSRGGSSRGGTA 324
PH P P P PLPP P A + +PPT +S
Sbjct: 1589 PHPLPDTPAPA-TPLPPVPPPA--------------------VAAAPPTLDSTASS---- 1623
Query: 325 ILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVVGTEPSAP-PAPPSPAFDPDRFLNS 383
LT + LT AP DP P A P+AP PA P P DP
Sbjct: 1624 ---LTSYDSEVATLTQGASAAP-GDPHPPGPPA------PAAPAPAAPQPGPDPPP---- 1669
Query: 384 PQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPPPQSVAGGRRGNCFF 443
G G+ + + H P + A+ L +A G G G
Sbjct: 1670 -------GTDSGIEEVDSRSSSDH-PLETISSASTLSSLSAEGGGSAGGGGGAGAGVA-- 1719
Query: 444 IQDDDSGEELKGHGAA-----PPIPSPPPSPPPSPAPLEPSSRVGRGEALFGG 491
SG EL A S P PP P + PS GR GG
Sbjct: 1720 -----SGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGG 1767
Score = 32.3 bits (72), Expect = 2.8
Identities = 47/195 (24%), Positives = 64/195 (32%), Gaps = 23/195 (11%)
Query: 742 DLEQEVDPLNVDHFSCTPLMWACALGHLEAAVLLFRWNRQALSIPDSLGRLPLSVAHSRG 801
++E E P V ++ AL L+ + + A P G L +G
Sbjct: 795 EMEYEQQPAPVPSMEKKRTVYQMALNKLDEILAAAQQTISASESPGPGGLASLGKHRPKG 854
Query: 802 HVRLARCLEELQRQEPSVEPPFALSPPSSSPDTGLSSVSSPSELSDGT--------FSVT 853
+ R +PS E P L P P L S + D FS +
Sbjct: 855 FFATESSFDPHHRAQPSYERPSFLPP---GPGLMLRQKSIGAAEDDRPYLAPPAMKFSRS 911
Query: 854 SAYSSAPDGSPPPAPLPASEMTMEDMAP---GQLSSGVPEAPLLLMDYEATNSKGPLSSL 910
+ + D PPP P P G+L+ P S GPL
Sbjct: 912 LSVPGSEDIPPPPTTSPPEPPYSTPPVPSSSGRLTPSPRGGPF------NPGSGGPL--- 962
Query: 911 PALPPASDDGAAPED 925
PA PAS DG +P D
Sbjct: 963 PASSPASFDGPSPPD 977
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 58.2 bits (139), Expect = 5e-08
Identities = 83/302 (27%), Positives = 102/302 (33%), Gaps = 106/302 (35%)
Query: 251 SPKVEPRALTLTSIPHA----------HPPEPPPLIAPL-PPELPKAHTSPSSSSSSSSS 299
SP + P A P+A PP PP+ AP PP P S + S + S
Sbjct: 414 SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS 473
Query: 300 GFAEPLEIRPSPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQADP---RPSMSL 356
A PL++ PSPP S ++P+ PQA P P + L
Sbjct: 474 LAAPPLQVPPSPPAS---------------------PPMSPSATPPPQAPPPLAAPPLQL 512
Query: 357 AVVVGTEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPA 416
A P APP+ A P + L SP P + P S P+
Sbjct: 513 A------KPPPQAPPALATPPLQALPSP----------------PASFPGQAPFS---PS 547
Query: 417 AALEPQAAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPI---------PSPPP 467
A+L P + PPPQ APP+ PSPP
Sbjct: 548 ASL-PMSPLATPPPQ---------------------------APPVLAAPLLQVPPSPPA 579
Query: 468 SP-------PPSPAPLEPSSRVGRGEALFGGPVGASELEPFSLSSFPDLMGELISDEAPS 520
SP PP+P P S AL GP P S S PDL G S A S
Sbjct: 580 SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGH--SSSATS 637
Query: 521 IP 522
P
Sbjct: 638 TP 639
Score = 55.1 bits (131), Expect = 4e-07
Identities = 90/341 (26%), Positives = 124/341 (36%), Gaps = 73/341 (21%)
Query: 218 TKPAPRTHACLCSGGLGSGSLTHKCSSTKHRIISPKVEPRALTLTSIPHAHPPEPPP--L 275
T+P+P +GG + SS+ + SP + T AHP +P P L
Sbjct: 218 TEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGL 277
Query: 276 IAPLPPEL--PKAHTSPSSSSSSSSSGFAEPLEIRPSPPTSRGGSSRGGTAILLLTGLEQ 333
A PP++ P+ +P+ SSS PL PSP + L+
Sbjct: 278 QALRPPQVTPPRKDAAPALGPLSSS-----PL-ATPSPSAA----------------LQS 315
Query: 334 RAGGLTPTRHLAPQADPRPSMSLAVVVGTEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGG 393
+A PT P + + LA + P +P APPS P P + T G
Sbjct: 316 QA---PPTLPATPHSSSL-TCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGS 371
Query: 394 QGVSPDFPEAEAAHT--PCSALEPAAALEPQA--AARGPPPQSVAGGRRGNCFFIQDDDS 449
P +A H+ P L P A PQA A PP Q
Sbjct: 372 -------PTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQ------------------ 406
Query: 450 GEELKGHGAAPPIP--SPPPSPPPSPAPLEPSS-RVGRGEALFGGPVGASELEPFSLSSF 506
APP P SPP SP +P+P P++ V +A F P PFS +
Sbjct: 407 ---------APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 457
Query: 507 PDLMGELI--SDEAPSIPAPTPQLSPALSTITDFSPEWSYP 545
P + S PS+ AP Q+ P+ SP + P
Sbjct: 458 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP 498
Score = 52.8 bits (125), Expect = 2e-06
Identities = 76/292 (26%), Positives = 94/292 (32%), Gaps = 72/292 (24%)
Query: 252 PKVEPRALTLTSIPHAHPP--EPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLEIRP 309
P P + + T P A PP PP +A PP+ P A +P PL+ P
Sbjct: 486 PASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP-------------PLQALP 532
Query: 310 SPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAP--QADPRPSMSLAVVVGTEPS-- 365
SPP S G + + L P AP Q P P S + P
Sbjct: 533 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 592
Query: 366 ---------------APPAPPSPAFDPDRFLNSPQ---------------RGQTYG--GG 393
AP PP P+ P L+ P RG G GG
Sbjct: 593 GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG 652
Query: 394 QGVSPDFPEAE--AAHTPCSALEPAAALEPQAAARGP---PPQSVAGGRRGNCFFIQDDD 448
SP P+AE A H + PA L + A P PP + G G C + +
Sbjct: 653 AAASPP-PDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEG 711
Query: 449 SGEELKGHGAAPPIPSPPPSPPPSPAPLEPSSRVGRGEALFGGPVGASELEP 500
GA P PSP S G+A G GAS P
Sbjct: 712 PESATPAPGALDPGPSPGTS---------------GGKAAAGAGAGASSRSP 748
Score = 47.8 bits (112), Expect = 6e-05
Identities = 74/280 (26%), Positives = 100/280 (35%), Gaps = 51/280 (18%)
Query: 270 PEPPPLIAPLPP-ELPKAHTSPSSSSSSSSSGFAEPLEIRPSPPTSRGGSSRGGTAILLL 328
P P P P PP E P+ S +S S++ PSP R S+ GG
Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTE----------PSPAARRRPSAGGG------ 233
Query: 329 TGLEQRAGGLTPTRHLAPQADP--RPSMSLAVVVGTEPSAPPAPPSPAFDPDRFLNSPQR 386
L++ A +R L+ A P P+ S GT P AP P P + L PQ
Sbjct: 234 --LQRPA-----SRSLSSSATPLSSPARSGPSARGT-PRAPAHPSQPKPKGLQALRPPQ- 284
Query: 387 GQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPPPQSVAGGRRGNCFFIQD 446
V+P +A A P S+ P A P AA + P ++ + Q
Sbjct: 285 ---------VTPPRKDAAPALGPLSS-SPLATPSPSAALQSQAPPTLPATPHSSSLTCQ- 333
Query: 447 DDSGEELKGHGAAPPIPSPPPSPPPSPAPLEPSSRVGRGEALFGGPV-----GASELEPF 501
APP PS PPS P+P P++ + G P P
Sbjct: 334 -----LATPLPLAPPSPSAPPSLQTLPSP--PATPPSQATTSLGSPTLQATHSFLPSPPL 386
Query: 502 SLSSFPDLMGELISDEAPSIPAPTPQLSPALSTITDFSPE 541
S + P P P+P SP LS + SP+
Sbjct: 387 SPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQ 426
Score = 39.7 bits (91), Expect = 0.017
Identities = 65/245 (26%), Positives = 87/245 (35%), Gaps = 34/245 (13%)
Query: 788 SLGRLPLSVAHSRGHVRLARCLEELQRQEPSVEPPFAL----SPPSSSPDTGLSSVSSPS 843
SLG L HS + L L P P AL +PPS LS +++PS
Sbjct: 368 SLGSPTLQATHS---FLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS 424
Query: 844 ELSDGTFSVTSAYSSAPDGSPPPAPLPASEMTMEDMAPGQLSSGVPEAPLLLMDYEATNS 903
+ +V AP PP P+ AP + P +P +A S
Sbjct: 425 PQAPNALAV--HLLQAPFSPPPSPPV---------QAPFSPPASPPVSPSATPPSQAPPS 473
Query: 904 -KGPLSSLPALPPASDDGAAPEDADSPQAVDVIPVDMISLAKQIIEATPERIKREDFVGL 962
P +P PPAS +P PQA + + LAK +A P + L
Sbjct: 474 LAAPPLQVPPSPPASPP-MSPSATPPPQAPPPLAAPPLQLAKPPPQA-PPALATPPLQAL 531
Query: 963 PEAGASMRERTGAVGLSETMSWLASYLENVDHFPSSTPPSELP--FERGRLAVPSAPSWA 1020
P AS G S + S S P +TPP + P L VP +P +
Sbjct: 532 PSPPASF---PGQAPFSPSASLPMS--------PLATPPPQAPPVLAAPLLQVPPSPPAS 580
Query: 1021 EFLSA 1025
L A
Sbjct: 581 PTLQA 585
Score = 34.3 bits (77), Expect = 0.73
Identities = 37/143 (25%), Positives = 51/143 (35%), Gaps = 28/143 (19%)
Query: 817 PSVEPPFAL--SPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPDGSP---PPAPLPA 871
PS P SPP++ P +S+ SP T T ++ +P SP PP P
Sbjct: 345 PSAPPSLQTLPSPPATPPSQATTSLGSP------TLQATHSFLPSPPLSPLATPPPQAPP 398
Query: 872 SEMTMEDMAPGQLSSGVPEAPLLLMDYEATNS------KGPLS-----------SLPALP 914
+ AP + P +PL +A N+ + P S S PA P
Sbjct: 399 ALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 458
Query: 915 PASDDGAAPEDADSPQAVDVIPV 937
P S P A A + V
Sbjct: 459 PVSPSATPPSQAPPSLAAPPLQV 481
Score = 33.1 bits (74), Expect = 1.6
Identities = 43/165 (26%), Positives = 67/165 (40%), Gaps = 19/165 (11%)
Query: 813 QRQEPSVEPPFALS--PPSSSPDTG---LSSVSSPSELSDGT--FSVTSAYSSAPDGSPP 865
Q P PP L+ PP + P L ++ SP G FS +++ +P +PP
Sbjct: 500 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 559
Query: 866 PAPLPASEMTMEDMAPGQLSSGVPEAPLLLMDYEATNSKGPLSSL--PALPPASDDGAAP 923
P P + + P +S +AP + GP +S+ P L A G P
Sbjct: 560 PQAPPVLAAPLLQVPPSPPASPTLQAP------RRPPTPGPDTSVSGPRLTLALAPGPPP 613
Query: 924 EDADSPQAVDVIPVDMISLAKQIIEATPERIKREDFVGLPEAGAS 968
+ SP + P D+ + +TPE ++ D PE GA+
Sbjct: 614 PPSRSPSSTLSGP-DLAGHSSS-ATSTPEELRGYD--SGPEGGAA 654
Score = 33.1 bits (74), Expect = 1.6
Identities = 32/106 (30%), Positives = 45/106 (42%), Gaps = 21/106 (19%)
Query: 817 PSVEPPFALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPDGSPPPAPLPASEMTM 876
P+++ P PP+ PDT SVS P + AP PPP+ P+S ++
Sbjct: 581 PTLQAP--RRPPTPGPDT---SVSGPR----------LTLALAPGPPPPPSRSPSSTLSG 625
Query: 877 EDMAPGQLSSGVPEAPLLLMDYEATNSKGPLSSLPALPPASDDGAA 922
D+A SS P L Y++ GP A PP + AA
Sbjct: 626 PDLAGH--SSSATSTPEELRGYDS----GPEGGAAASPPPDAELAA 665
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 58.2 bits (139), Expect = 5e-08
Identities = 83/302 (27%), Positives = 102/302 (33%), Gaps = 106/302 (35%)
Query: 251 SPKVEPRALTLTSIPHA----------HPPEPPPLIAPL-PPELPKAHTSPSSSSSSSSS 299
SP + P A P+A PP PP+ AP PP P S + S + S
Sbjct: 375 SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS 434
Query: 300 GFAEPLEIRPSPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQADP---RPSMSL 356
A PL++ PSPP S ++P+ PQA P P + L
Sbjct: 435 LAAPPLQVPPSPPAS---------------------PPMSPSATPPPQAPPPLAAPPLQL 473
Query: 357 AVVVGTEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPA 416
A P APP+ A P + L SP P + P S P+
Sbjct: 474 A------KPPPQAPPALATPPLQALPSP----------------PASFPGQAPFS---PS 508
Query: 417 AALEPQAAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPI---------PSPPP 467
A+L P + PPPQ APP+ PSPP
Sbjct: 509 ASL-PMSPLATPPPQ---------------------------APPVLAAPLLQVPPSPPA 540
Query: 468 SP-------PPSPAPLEPSSRVGRGEALFGGPVGASELEPFSLSSFPDLMGELISDEAPS 520
SP PP+P P S AL GP P S S PDL G S A S
Sbjct: 541 SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGH--SSSATS 598
Query: 521 IP 522
P
Sbjct: 599 TP 600
Score = 52.8 bits (125), Expect = 2e-06
Identities = 76/292 (26%), Positives = 94/292 (32%), Gaps = 72/292 (24%)
Query: 252 PKVEPRALTLTSIPHAHPP--EPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLEIRP 309
P P + + T P A PP PP +A PP+ P A +P PL+ P
Sbjct: 447 PASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP-------------PLQALP 493
Query: 310 SPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAP--QADPRPSMSLAVVVGTEPS-- 365
SPP S G + + L P AP Q P P S + P
Sbjct: 494 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 553
Query: 366 ---------------APPAPPSPAFDPDRFLNSPQ---------------RGQTYG--GG 393
AP PP P+ P L+ P RG G GG
Sbjct: 554 GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG 613
Query: 394 QGVSPDFPEAE--AAHTPCSALEPAAALEPQAAARGP---PPQSVAGGRRGNCFFIQDDD 448
SP P+AE A H + PA L + A P PP + G G C + +
Sbjct: 614 AAASPP-PDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEG 672
Query: 449 SGEELKGHGAAPPIPSPPPSPPPSPAPLEPSSRVGRGEALFGGPVGASELEP 500
GA P PSP S G+A G GAS P
Sbjct: 673 PESATPAPGALDPGPSPGTS---------------GGKAAAGAGAGASSRSP 709
Score = 44.7 bits (104), Expect = 5e-04
Identities = 95/373 (25%), Positives = 128/373 (34%), Gaps = 66/373 (17%)
Query: 217 PTKPAPRTHACL----CSGGLGSGSLTHKCSSTKHRIISPKVEPRA-LTLTSIPHAHPPE 271
P P P T A L +G +G L + I P+ PRA T TS P P
Sbjct: 33 PRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI-PESAPRAGPTRTSRP---PAS 88
Query: 272 PPPLIAPLPPELPKAHTSPSS-SSSSSSSGFAEP-------LEIRPSPPTSRGGSSRGGT 323
AP P +TSP SS +SG P L I +RG ++
Sbjct: 89 GRGERAP-----PAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPK 143
Query: 324 AILLLTGLEQRAGGLTPTRHLAPQADPRPSMSL-AVVVGTE-------PSAPPAPP---- 371
L G + G TP P P+M+ + GTE PSA P PP
Sbjct: 144 RSALSAGARRDTSGPTP-------GTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 196
Query: 372 ----SPAFDPDRFLNSPQRGQTYGGGQGVS-PDFPEAEAAHTPCSALE---PAAALEPQA 423
S A + SP + G G+ P ++ TP S+ P+A P+A
Sbjct: 197 RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA 256
Query: 424 AARGPPPQ----------SVAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPPPSPPPSP 473
A P+ V R+ + S +APP PS PPS P
Sbjct: 257 PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLP 316
Query: 474 APLEPSSRVGRGEALFGGPV-----GASELEPFSLSSFPDLMGELISDEAPSIPAPTPQL 528
+P P++ + G P P S + P P P+P
Sbjct: 317 SP--PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPA 374
Query: 529 SPALSTITDFSPE 541
SP LS + SP+
Sbjct: 375 SPPLSPLATPSPQ 387
Score = 39.7 bits (91), Expect = 0.017
Identities = 65/245 (26%), Positives = 87/245 (35%), Gaps = 34/245 (13%)
Query: 788 SLGRLPLSVAHSRGHVRLARCLEELQRQEPSVEPPFAL----SPPSSSPDTGLSSVSSPS 843
SLG L HS + L L P P AL +PPS LS +++PS
Sbjct: 329 SLGSPTLQATHS---FLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS 385
Query: 844 ELSDGTFSVTSAYSSAPDGSPPPAPLPASEMTMEDMAPGQLSSGVPEAPLLLMDYEATNS 903
+ +V AP PP P+ AP + P +P +A S
Sbjct: 386 PQAPNALAV--HLLQAPFSPPPSPPV---------QAPFSPPASPPVSPSATPPSQAPPS 434
Query: 904 -KGPLSSLPALPPASDDGAAPEDADSPQAVDVIPVDMISLAKQIIEATPERIKREDFVGL 962
P +P PPAS +P PQA + + LAK +A P + L
Sbjct: 435 LAAPPLQVPPSPPASPP-MSPSATPPPQAPPPLAAPPLQLAKPPPQA-PPALATPPLQAL 492
Query: 963 PEAGASMRERTGAVGLSETMSWLASYLENVDHFPSSTPPSELP--FERGRLAVPSAPSWA 1020
P AS G S + S S P +TPP + P L VP +P +
Sbjct: 493 PSPPASF---PGQAPFSPSASLPMS--------PLATPPPQAPPVLAAPLLQVPPSPPAS 541
Query: 1021 EFLSA 1025
L A
Sbjct: 542 PTLQA 546
Score = 34.3 bits (77), Expect = 0.73
Identities = 37/143 (25%), Positives = 51/143 (35%), Gaps = 28/143 (19%)
Query: 817 PSVEPPFAL--SPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPDGSP---PPAPLPA 871
PS P SPP++ P +S+ SP T T ++ +P SP PP P
Sbjct: 306 PSAPPSLQTLPSPPATPPSQATTSLGSP------TLQATHSFLPSPPLSPLATPPPQAPP 359
Query: 872 SEMTMEDMAPGQLSSGVPEAPLLLMDYEATNS------KGPLS-----------SLPALP 914
+ AP + P +PL +A N+ + P S S PA P
Sbjct: 360 ALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 419
Query: 915 PASDDGAAPEDADSPQAVDVIPV 937
P S P A A + V
Sbjct: 420 PVSPSATPPSQAPPSLAAPPLQV 442
Score = 33.1 bits (74), Expect = 1.6
Identities = 43/165 (26%), Positives = 67/165 (40%), Gaps = 19/165 (11%)
Query: 813 QRQEPSVEPPFALS--PPSSSPDTG---LSSVSSPSELSDGT--FSVTSAYSSAPDGSPP 865
Q P PP L+ PP + P L ++ SP G FS +++ +P +PP
Sbjct: 461 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 520
Query: 866 PAPLPASEMTMEDMAPGQLSSGVPEAPLLLMDYEATNSKGPLSSL--PALPPASDDGAAP 923
P P + + P +S +AP + GP +S+ P L A G P
Sbjct: 521 PQAPPVLAAPLLQVPPSPPASPTLQAP------RRPPTPGPDTSVSGPRLTLALAPGPPP 574
Query: 924 EDADSPQAVDVIPVDMISLAKQIIEATPERIKREDFVGLPEAGAS 968
+ SP + P D+ + +TPE ++ D PE GA+
Sbjct: 575 PPSRSPSSTLSGP-DLAGHSSS-ATSTPEELRGYD--SGPEGGAA 615
Score = 33.1 bits (74), Expect = 1.6
Identities = 32/106 (30%), Positives = 45/106 (42%), Gaps = 21/106 (19%)
Query: 817 PSVEPPFALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPDGSPPPAPLPASEMTM 876
P+++ P PP+ PDT SVS P + AP PPP+ P+S ++
Sbjct: 542 PTLQAP--RRPPTPGPDT---SVSGPR----------LTLALAPGPPPPPSRSPSSTLSG 586
Query: 877 EDMAPGQLSSGVPEAPLLLMDYEATNSKGPLSSLPALPPASDDGAA 922
D+A SS P L Y++ GP A PP + AA
Sbjct: 587 PDLAGH--SSSATSTPEELRGYDS----GPEGGAAASPPPDAELAA 626
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 58.2 bits (139), Expect = 5e-08
Identities = 79/302 (26%), Positives = 101/302 (33%), Gaps = 48/302 (15%)
Query: 256 PRALTLTSIPHAHPPEPPPLIAPLPPEL-------------PK-AHTSPSSSSSSSSSGF 301
P+ T P P P P AP PP PK A T P+++ S G
Sbjct: 918 PKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGP 977
Query: 302 AEPL-EIRPSPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVV 360
A P + P+PP + S +GG A G P+ +P A P P +
Sbjct: 978 ATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPA 1037
Query: 361 GTEPS------APPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALE 414
T PS A P P P L SP+ G P P + A TP
Sbjct: 1038 ATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG----------PATPSLKGAPTP----- 1082
Query: 415 PAAALEPQAAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPPP------- 467
PAA P + GP S G G H AP P+ P
Sbjct: 1083 PAAT--PPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGL 1140
Query: 468 -SPPPSPAPLEPSSR--VGRGEALFGGPVGASELEPFSLSSFPDLMGELISDEAPSIPAP 524
+PPP AP P++ +G P GA + S + AP+ PA
Sbjct: 1141 ATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1200
Query: 525 TP 526
TP
Sbjct: 1201 TP 1202
Score = 53.1 bits (126), Expect = 2e-06
Identities = 84/315 (26%), Positives = 108/315 (34%), Gaps = 47/315 (14%)
Query: 251 SPKVEPRALTLTSIPHAHPPEP--PPLIAPLPPELPKAHTSPSSSSSSSSSGFAEP-LEI 307
SP P ++ P A PP P P PLP P T+P+++ S G A P L+
Sbjct: 1022 SPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAP---TTPAATLPSPKGGPATPSLKG 1078
Query: 308 RPSPPTSRGGSSRGGTAILLLTGL---------EQRAGGLTPTRHLAP----QADPRPSM 354
P+PP + S +GG A G + G TP AP P P
Sbjct: 1079 APTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG 1138
Query: 355 SLAVV----VGTEPSA-PPAP------PSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEA 403
LA T P+A PP+P P P P +P + GG SP
Sbjct: 1139 GLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK--GGLATPSPKGAPT 1196
Query: 404 EAAHTPCSALEPAAALEPQAAARGP--PPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPP 461
A TP S A P+ A P P S GG + A PP
Sbjct: 1197 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG-------LATPSPKGAPTTPAATPP 1249
Query: 462 IPS------PPPSPPPSPAPLEPSSRVGRGEALFGGPVGASELEPFSLSSFPDLMGELIS 515
P PP P PA PS + G G + + P S P +
Sbjct: 1250 SPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGA 1309
Query: 516 DEAPSIPAPTPQLSP 530
P+ P+P+ SP
Sbjct: 1310 PTPPAATPPSPKGSP 1324
Score = 52.8 bits (125), Expect = 2e-06
Identities = 75/291 (25%), Positives = 102/291 (35%), Gaps = 52/291 (17%)
Query: 265 PHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLEIRPSPPTSRGGSSRGGTA 324
P P PP AP PP A T PS S + P + P+PP S + GT
Sbjct: 1297 PKGGPATSPPKGAPTPP----AATPPSPKGSPGT----PPPKGAPTPPAVTPPSPK-GTP 1347
Query: 325 ILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVVGTEPSAPPAP------PSPAFDPD 378
L T + G TP + + P P + G PP+P PSP DP
Sbjct: 1348 TLPATTPSSKGGPTTP----SSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPT 1403
Query: 379 RFLNSPQRGQTYGGGQGVSPDFP-EAEAAHTPCSALEPAAALEPQAAARGPPPQSVAGGR 437
P + +P P E A TP A+ P + + P + GG
Sbjct: 1404 SPAVIPLSPKK-------APATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGG- 1455
Query: 438 RGNCFFIQDDDSGEELKGHGAAPPIPSPPPSPPPSPAPLEPSSRVGRGEALFGGPVGASE 497
+ KG P + P P PP+P + SS + A P+GA
Sbjct: 1456 ----------PATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPAT-PAPMGAPT 1504
Query: 498 LE----------PFSLSSFPDLM---GELISDEAPSIPAPTPQLSPALSTI 535
L P + SS D + L+S + P+ AP L P T+
Sbjct: 1505 LPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTV 1555
Score = 52.0 bits (123), Expect = 3e-06
Identities = 82/303 (27%), Positives = 103/303 (33%), Gaps = 62/303 (20%)
Query: 256 PRALTLTSIPHAHPPEPPPLIAPLPPEL----PK----------AHTSPSSSSSSSSSGF 301
P A T S P P P P AP+PP PK A T+P+++ S G
Sbjct: 1082 PPAATPPS-PKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGL 1140
Query: 302 AEP------LEIRPSPPTSRGGSS----RGGTAILLLTGLEQRAGGLTPTRHLAPQAD-- 349
A P +PP+ +GG + +G T + G TP+ AP
Sbjct: 1141 ATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1200
Query: 350 --PRPSMSLAVVVGTEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAH 407
P P LA PS AP +PA P SP+ G +G P AA
Sbjct: 1201 TPPSPKGGLAT-----PSPKGAPTTPAATPP----SPKGGLATPSPKGA----PTTPAAT 1247
Query: 408 TPCSALEPAAALEPQAAARGPP---PQSVAGGRRGNCFFIQDDDSGEELKGHGAAP-PIP 463
P PA P A PP P S+ GG H AP P
Sbjct: 1248 PPSPKGGPATP--PPKGAPTPPAATPPSLKGGLA--------------TPPHKGAPNPAV 1291
Query: 464 SPPPSPPPSPAPLEPSSRVGRGEALFGGPVGASELEPFSLSSFPDLMGELISDEAPSIPA 523
PPSP PA P A P G+ P + P + P++PA
Sbjct: 1292 VTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPA 1351
Query: 524 PTP 526
TP
Sbjct: 1352 TTP 1354
Score = 50.1 bits (118), Expect = 1e-05
Identities = 80/287 (27%), Positives = 102/287 (35%), Gaps = 40/287 (13%)
Query: 254 VEPRALTLTSIPHAHPPEPPPLIAPLP---PELPKAHTSPSSSSSSSSSGFAEPLEIRPS 310
+ P+ +TL P P P + P P P P +P+ S +SSS A
Sbjct: 873 LSPKGVTL---PPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKG 929
Query: 311 PPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAP----QADPRPSMSLAVVVGTEPSA 366
P S S +G T + G TP+ AP P P A
Sbjct: 930 IPAS--PSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPT 987
Query: 367 PPA--PPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAA 424
PPA PPSP P SP+ T V+P P+ A TP P A P AA
Sbjct: 988 PPAATPPSPKGGP--ATPSPKGAPT---PPAVTPPSPKGSPAATPF----PKGASTPPAA 1038
Query: 425 ARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPI---PSPPPSPPPSP--APLEPS 479
P S A + KG A P + P+PP + PPSP P PS
Sbjct: 1039 TPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPS 1098
Query: 480 SRVGRGEALFGGPVGASELEPFSLSSFPDLMGELISDEAPSIPAPTP 526
+G + P A+ P + P G AP+ PA TP
Sbjct: 1099 P---KGAPM---PPAATPPSPKGGLATPPHKG------APTTPAATP 1133
Score = 47.8 bits (112), Expect = 6e-05
Identities = 71/269 (26%), Positives = 96/269 (35%), Gaps = 45/269 (16%)
Query: 272 PPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLEIRPSPPTSRGGSSRGGTA------- 324
P +P PP PK +PS+ + S G P + P+P + G A
Sbjct: 850 PATTHSPTPPS-PKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQA 908
Query: 325 -ILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVVGTEPS--APPAPPSPAFDPDRFL 381
L +T + TP P A P P + T PS PA PSP + P
Sbjct: 909 PALSMTSSSPKKARATPAPKGIP-ASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPA 967
Query: 382 NSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPPPQSVAGGRRGNC 441
+P + GG SP A TP S A P+ A P P +V
Sbjct: 968 ATPPSPK--GGPATPSPKGAPTPPAATPPSPKGGPATPSPKGA---PTPPAV-------- 1014
Query: 442 FFIQDDDSGEELKGHGAAPPIP----SPPPSPPPSPAPLEPSSRVGRGEALFGGPVGASE 497
+ KG AA P P +PP + PPSP ++ + +G A+
Sbjct: 1015 -------TPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPT---TPAATL 1064
Query: 498 LEPFSLSSFPDLMGELISDEAPSIPAPTP 526
P + P L G AP+ PA TP
Sbjct: 1065 PSPKGGPATPSLKG------APTPPAATP 1087
Score = 43.5 bits (101), Expect = 0.001
Identities = 82/346 (23%), Positives = 119/346 (34%), Gaps = 42/346 (12%)
Query: 215 THPTKPAPRTHACLCSGGLGS-GSLTHKCSSTKHRII--SPKVEPRALTLTSIPHAHPPE 271
T P K AP A GS G+ K + T + SPK P T P
Sbjct: 1303 TSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTT 1362
Query: 272 PPPLIAPLPPELPKAHT-SPSSSSSSSSSGFAEPLEIRPSPPTSRGGSSRGGTAILLLTG 330
P P PP +H P+ + S G P+ P+ +G + A++ L+
Sbjct: 1363 PSSKEGPTPPAATPSHKGGPAMTPPSPKRG--------PAIPSPKGDPT--SPAVIPLSP 1412
Query: 331 LE------QRAGGLTPTR-HLAPQADPRPSMSLAVVVGTEPSAPPAPPSPAFDPDRFLNS 383
+ R G TP++ L P A S+ A + P PA PS DP +
Sbjct: 1413 KKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPAT-SAPKGGPATPSSKGDPTLPAVT 1471
Query: 384 PQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPA-AALEPQAAARGP-PPQSVAGGRRGNC 441
P + + V+ +A TP P A+ P + P P S
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTA 1531
Query: 442 FFIQDDDSGEELKGHGAAPP---IPSP---PPSPPPSPAPLEPSSRVGRGEALFGGPVGA 495
+ PP +PSP P P P AP PSS+
Sbjct: 1532 TLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEAS---------SP 1582
Query: 496 SELEPFSLSSFPDLMGELISDEAPSIPAPTPQLSPALSTITDFSPE 541
+ P + P LI P++ +P+P+ +P +T SPE
Sbjct: 1583 PAVTPSTYKGAPSPKELLI---PPAVTSPSPKEAPTPPAVTPPSPE 1625
Score = 42.4 bits (98), Expect = 0.003
Identities = 84/391 (21%), Positives = 130/391 (33%), Gaps = 88/391 (22%)
Query: 210 QQILDTHPTKPAPRTHACLCSGGLGSGSLTHKCSSTKHRII---SPKVEPRALTLTSIPH 266
+Q+ + K AP T A +G+ +L S+ + S + +P A T T +
Sbjct: 1482 KQVATSSSPKKAPATPA-----PMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSK 1536
Query: 267 AHPPE--------PPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLEIRPSPPTSRGGS 318
P PP + P P + P T + ++ SS + P + PS T +G
Sbjct: 1537 KTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPS--TYKGA- 1593
Query: 319 SRGGTAILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVVGTEPSAPPAPPSPAFDPD 378
P P L T PS AP PA P
Sbjct: 1594 -------------------------------PSPKELLIPPAVTSPSPKEAPTPPAVTPP 1622
Query: 379 RFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAA------ALEPQA-----AARG 427
SP++G +G +P P + S PA+ A PQA A +G
Sbjct: 1623 ----SPEKGPATPAPKG-TPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKG 1677
Query: 428 PPPQS---VAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPPPS---------PPPSPAP 475
P VA G + K A P P PS +PAP
Sbjct: 1678 PTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAP 1737
Query: 476 LEP----SSRVGRGEALFGGPVG------ASELEPFSLSSFPDLMGELISDEAPSIPAPT 525
L P SS+ +G+ P G + P + ++F ++ + S + P+P
Sbjct: 1738 LLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPP 1797
Query: 526 PQLSPALSTITDFSPEWSYPEGGVKVLITGP 556
L A S + P+ + +++ P
Sbjct: 1798 VSLPLAPSPVPTLPPKQQFLPSSPGLVLESP 1828
Score = 41.6 bits (96), Expect = 0.005
Identities = 84/346 (24%), Positives = 119/346 (34%), Gaps = 76/346 (21%)
Query: 252 PKVEPRALTLTSIPHAHP-----PEPPPLIAPLP-----PELPKAHTSPSSSSSSSSSGF 301
P E TL +P A P P APL PE+PK+ SPS + + G
Sbjct: 689 PVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGT 748
Query: 302 AE-----------PLEIRPSP-PTSRGGSSRGGTAILLLTGL------------------ 331
+ P+ P PT G+S ++ LT L
Sbjct: 749 KKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRP 808
Query: 332 ---EQRAGGLTPTRHLAPQADP-----RPSMSLAVVVGTEPSA---PPAPPSPAFDPDRF 380
+ AG TP +L+ P P SL+ + A P PPSP P
Sbjct: 809 PTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPS 868
Query: 381 LNSP--QRGQTYGGGQGVSPD-----FPEAEAAHTPCSALEPAAAL---EPQAAARGPPP 430
+P +G T + +P FP+ E TP PA ++ P+ A P P
Sbjct: 869 AVTPLSPKGVTLPPKETPTPSVVNLPFPK-EGPATPAPKQAPALSMTSSSPKKARATPAP 927
Query: 431 QSVAGGRRGNCFFIQDDDSGEELKGHGAAPP---IPSPPPSPPPSP--APLEPSSRVGRG 485
+ + + KG A P P+PP + PPSP P PS +
Sbjct: 928 KGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPK---- 983
Query: 486 EALFGGPVGASELEPFSLSSFPDLMGELISDEAPSIPAPTPQLSPA 531
G P + P S P + P++ P+P+ SPA
Sbjct: 984 ----GAPTPPAATPP-SPKGGPATPSPKGAPTPPAVTPPSPKGSPA 1024
Score = 36.2 bits (82), Expect = 0.19
Identities = 48/204 (23%), Positives = 78/204 (38%), Gaps = 16/204 (7%)
Query: 236 GSLTHKCSSTKHRIISPKVEPR------ALTLTSIPHAHPPEPPPLIAPLPPELPKAHTS 289
G T +T+ + P+ E AL++T+ P PP +P P + P + +
Sbjct: 3 GEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAAN 62
Query: 290 PSSSSSSSSSGFAEPLEIRPSPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQAD 349
+S S S+ + PLE+ P P +S G + GTA T L G ++P A
Sbjct: 63 QASPFPSPSTIASTPLEV-PFPQSSSGTALPLGTAPEAPTFLPNLIG-----PPISPAAL 116
Query: 350 PRPSMSLAVVVGTEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTP 409
S +A + PS+ A P +S Q+ + SP + +
Sbjct: 117 ALASPMIAPTLKGTPSSSAPLALVALAP----HSVQKSSAFPPNLLTSPPSVAVAESGSV 172
Query: 410 CSALEPAAALEPQAAARGPPPQSV 433
+ P A EP+ P + V
Sbjct: 173 ITLSAPIAPSEPKTNLNKVPSEVV 196
Score = 31.2 bits (69), Expect = 6.2
Identities = 35/136 (25%), Positives = 53/136 (38%), Gaps = 14/136 (10%)
Query: 822 PFALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPDGSPPPAPLPASEMTMEDMAP 881
P +P P T SS +SP D + S P + PAPL + A
Sbjct: 1694 PIITAPTRKGPQTKKSSATSPPICPDPS---AKNGSKGPLSTVAPAPLLPVQKDSSKTAK 1750
Query: 882 GQLSSGVPEAPLLLMDYEATNSKGPLSS------LPALPPASDDGAAPEDADSPQAVDVI 935
G+ +S P+ PL + +A+ PL++ LP AS A P A
Sbjct: 1751 GKDASHSPKGPLAPPESKAST---PLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPS-- 1805
Query: 936 PVDMISLAKQIIEATP 951
PV + +Q + ++P
Sbjct: 1806 PVPTLPPKQQFLPSSP 1821
Score = 30.8 bits (68), Expect = 8.1
Identities = 60/249 (24%), Positives = 90/249 (36%), Gaps = 40/249 (16%)
Query: 811 ELQRQEPSVEPPFALSPPSSSPDTGLSS-------VSSPSEL---SDGTFSVTSAYSSAP 860
E+ + PS P A +PP + G+S SSP E G + S+ +
Sbjct: 729 EIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLT 788
Query: 861 DGSPPPAPLPASEMTMEDMAPGQLSSGVPEAPLLLMDYEATNSKGPLSSLPA--LP---- 914
+ P+PL S P + S P+ P+ N P+S + A LP
Sbjct: 789 YLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPI-------GNLSSPVSPVEASFLPENSL 841
Query: 915 --PASDDGAAPEDADSPQAVDVIPVD--MISLAKQIIEATPERIKREDFVGL--PEAGAS 968
S D A + +P + P + L+ + + P+ V L P+ G +
Sbjct: 842 SFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPA 901
Query: 969 MRERTGAVGLSETMS-----WLASYLENVDHFPS----STPPSEL-PFERGRLAVPSAPS 1018
A LS T S + + PS TPP+ P +G A PS P
Sbjct: 902 TPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPS-PK 960
Query: 1019 WAEFLSAST 1027
WA A+T
Sbjct: 961 WAPTPPAAT 969
Score = 30.8 bits (68), Expect = 8.1
Identities = 34/128 (26%), Positives = 48/128 (37%), Gaps = 19/128 (14%)
Query: 821 PPFALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPDGSPPPAPLPASEMTMEDMA 880
P A +PP+++P + ++PS G + + +P GSP P P T
Sbjct: 982 PKGAPTPPAATPPSPKGGPATPSP--KGAPTPPAVTPPSPKGSPAATPFPKGASTPPAAT 1039
Query: 881 PGQ---------LSSGVPEAPLLLMDY----EATNS-KGPLSSLPALPPASDDGAA---P 923
P L G P P + AT S KG + A PP+ G A P
Sbjct: 1040 PPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP 1099
Query: 924 EDADSPQA 931
+ A P A
Sbjct: 1100 KGAPMPPA 1107
Score = 30.8 bits (68), Expect = 8.1
Identities = 29/115 (25%), Positives = 50/115 (43%), Gaps = 18/115 (15%)
Query: 815 QEPSVEPPFALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPDGSPPPAPLPASEM 874
++ S P L+PP S T L++ + L +++ S+AP PP LP +
Sbjct: 1752 KDASHSPKGPLAPPESKASTPLTAAAFEKVLPK---PESASVSAAPS---PPVSLPLAPS 1805
Query: 875 TMEDMAPGQLSSGVPEAPLLLMDYEATNSKGPLSS------LPALPPASDDGAAP 923
+ + P Q +P +P L+++ + PL+ LP +PP G P
Sbjct: 1806 PVPTLPPKQ--QFLPSSPGLVLE----SPSKPLAPADEDELLPLIPPEPISGGVP 1854
>gi|126116596 asp (abnormal spindle)-like, microcephaly associated
[Homo sapiens]
Length = 3477
Score = 57.4 bits (137), Expect = 8e-08
Identities = 51/176 (28%), Positives = 79/176 (44%), Gaps = 34/176 (19%)
Query: 1045 QRELY----EAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWI--------- 1091
QRE Y +A +V+Q +FR + RR + + AA +IQ YR+Y+Q T+
Sbjct: 2159 QREKYLTILKAVKVLQASFRGVRVRRTLRKMQTAATLIQSNYRRYRQQTYFNKLKKITKT 2218
Query: 1092 -----------ALKFALYKKMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRS--Y 1138
++F Y K+ + I IQ+ FR ++ + AA LIQ+ +R+
Sbjct: 2219 VQQRYWAMKERNIQFQRYNKLRHSVIYIQAIFRGKKARRHLKMMHIAATLIQRRFRTLMM 2278
Query: 1139 RRRPGPPHRTSATLPARNKGSFLTKKQDQ------AARKIMRFLRR--CRHRMREL 1186
RRR +T+ + + + TK Q A KI RR R RMRE+
Sbjct: 2279 RRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIKIQSSYRRWMIRKRMREM 2334
Score = 53.9 bits (128), Expect = 9e-07
Identities = 37/114 (32%), Positives = 58/114 (50%), Gaps = 20/114 (17%)
Query: 1046 RELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYR-----KYKQLTWIALKFALY-- 1098
+ ++ +A +IQ+ FR RR + A +QR YR K+K ++ L+ A
Sbjct: 2405 KSMHSSATLIQSRFRSLLVRRRFISLKKATIFVQRKYRATICAKHKLYQFLHLRKAAITI 2464
Query: 1099 -------------KKMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYR 1139
++M +AA+LIQ+ FR Y FQ + A++LIQQHYR+YR
Sbjct: 2465 QSSYRRLMVKKKLQEMQRAAVLIQATFRMYRTYITFQTWKHASILIQQHYRTYR 2518
Score = 53.9 bits (128), Expect = 9e-07
Identities = 42/162 (25%), Positives = 74/162 (45%), Gaps = 36/162 (22%)
Query: 1045 QRELY----EAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALKFALYKK 1100
QRE Y +A VIQ A++ K R+L ++ A+ VIQ YR Y+Q + Y+K
Sbjct: 2523 QRENYIRQWHSAVVIQAAYKGMKARQLLREKHKASIVIQSTYRMYRQ-------YCFYQK 2575
Query: 1101 MTQAAILIQSKFRSYYE-------------------------QKRFQQSRRAAVLIQQHY 1135
+ A +IQ K+R+ + +K+ Q+ +AA++IQ+H
Sbjct: 2576 LQWATKIIQEKYRANKKKQKVFQHNELKKETCVQAGFQDMNIKKQIQEQHQAAIIIQKHC 2635
Query: 1136 RSYRRRPGPPHRTSATLPARNKGSFLTKKQDQAARKIMRFLR 1177
++++ R H + + + + LT + QA I + R
Sbjct: 2636 KAFKIRKHYLHLRATVVSIQRRYRKLTAVRTQAVICIQSYYR 2677
Score = 52.8 bits (125), Expect = 2e-06
Identities = 42/154 (27%), Positives = 79/154 (51%), Gaps = 25/154 (16%)
Query: 1046 RELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKY----KQ-LTWIALKFALY-- 1098
R ++AA IQ+AFR K ++ + AA VIQ+ +R + KQ + +I L+ A+
Sbjct: 1895 RREHQAALKIQSAFRMAKAQKQFRLFKTAALVIQQNFRAWTAGRKQCMEYIELRHAVLVL 1954
Query: 1099 -------------KKMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYRRRPGPP 1145
++ + AI+IQS +R + +QK+++ ++AA+LIQ++YR+Y
Sbjct: 1955 QSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQN 2014
Query: 1146 HRTSATLPARNKGSFLTKKQDQAARKIMRFLRRC 1179
H L + K + +T + K+ + ++ C
Sbjct: 2015 H-----LYLKTKAAVVTLQSAYRGMKVRKRIKDC 2043
Score = 50.4 bits (119), Expect = 1e-05
Identities = 41/158 (25%), Positives = 70/158 (44%), Gaps = 14/158 (8%)
Query: 1046 RELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALKFALYKKMTQAA 1105
+E ++AA +IQ + +K R+ IQR YRK L TQA
Sbjct: 2622 QEQHQAAIIIQKHCKAFKIRKHYLHLRATVVSIQRRYRK------------LTAVRTQAV 2669
Query: 1106 ILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYRRRPGPPHRTSATLPARNKGSFLTKKQ 1165
I IQS +R + +K Q RAA LIQ YR +R + + +A + +N + +
Sbjct: 2670 ICIQSYYRGFKVRKDIQNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVK 2729
Query: 1166 DQAAR--KIMRFLRRCRHRMRELKQNQELEGLPQPGLA 1201
+ + + +R + R +K Q+L+ + + +A
Sbjct: 2730 TERKNFLAVQKSVRTIQAAFRGMKVRQKLKNVSEEKMA 2767
Score = 49.3 bits (116), Expect = 2e-05
Identities = 31/99 (31%), Positives = 53/99 (53%), Gaps = 11/99 (11%)
Query: 1047 ELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALKFALYKKMTQAAI 1106
++ +AA +Q A+R YK R+L +QQ +AA IQ +R Y K Y+ + Q+ I
Sbjct: 1800 QVKKAATCLQAAYRGYKVRQLIKQQSIAALKIQSAFRGYN-------KRVKYQSVLQSII 1852
Query: 1107 LIQSKFRSYY----EQKRFQQSRRAAVLIQQHYRSYRRR 1141
IQ +R+Y + F +++ A + +Q YR ++ R
Sbjct: 1853 KIQRWYRAYKTLHDTRTHFLKTKAAVISLQSAYRGWKVR 1891
Score = 48.9 bits (115), Expect = 3e-05
Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 21/133 (15%)
Query: 1044 EQRELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKY-KQLTWIALKFA------ 1096
E EL A V+Q+ ++ RR ++Q A +IQ YR + +Q W +K A
Sbjct: 1943 EYIELRHAVLVLQSMWKGKTLRRQLQRQHKCAIIIQSYYRMHVQQKKWKIMKKAALLIQK 2002
Query: 1097 -------------LYKKMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYR-RRP 1142
LY K A + +QS +R +KR + +AAV IQ YR+Y+ ++
Sbjct: 2003 YYRAYSIGREQNHLYLKTKAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKK 2062
Query: 1143 GPPHRTSATLPAR 1155
+R SA + R
Sbjct: 2063 YATYRASAIIIQR 2075
Score = 48.1 bits (113), Expect = 5e-05
Identities = 33/137 (24%), Positives = 73/137 (53%), Gaps = 17/137 (12%)
Query: 1018 SWAEFLSASTSGKMESDFALLTLSDHEQRELYEAAR-VIQTAFRKYKGRRLKEQQEVAAA 1076
S+ +L A+ + + L D ++ E+ +++ +IQ+ FRK+K R+++ Q + A
Sbjct: 1389 SYKRYLWATVTIQRHWRAYLRRKQDQQRYEMLKSSTLIIQSMFRKWKQRKMQSQVK-ATV 1447
Query: 1077 VIQRCYRKY---KQL----------TWIALKFAL--YKKMTQAAILIQSKFRSYYEQKRF 1121
++QR +R++ KQ +W + L Y + ++IQ +FR + QK +
Sbjct: 1448 ILQRAFREWHLRKQAKEENSAIIIQSWYRMHKELRKYIYIRSCVVIIQKRFRCFQAQKLY 1507
Query: 1122 QQSRRAAVLIQQHYRSY 1138
++ + + + IQ++Y++Y
Sbjct: 1508 KRRKESILTIQKYYKAY 1524
Score = 47.8 bits (112), Expect = 6e-05
Identities = 48/144 (33%), Positives = 75/144 (52%), Gaps = 27/144 (18%)
Query: 1051 AARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALKFALYKK----MTQAAI 1106
AA IQ AF + R+L E Q+ AA IQ L+ A+Y++ +AAI
Sbjct: 2817 AAVTIQKAFCRMVTRKL-ETQKCAALRIQ-----------FFLQMAVYRRRFVQQKRAAI 2864
Query: 1107 LIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSY-----RRRPGPPHRTSA-TLPARNKGSF 1160
+Q FR++ +K+F R+AAV++Q HYR++ +R+ R+S + AR+KG F
Sbjct: 2865 TLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKHQRQVYLQIRSSVIIIQARSKG-F 2923
Query: 1161 LTKKQDQAAR----KIMRFLRRCR 1180
+ K++ Q + KI RR R
Sbjct: 2924 IQKRKFQEIKNSTIKIQAMWRRYR 2947
Score = 45.8 bits (107), Expect = 2e-04
Identities = 36/138 (26%), Positives = 66/138 (47%), Gaps = 6/138 (4%)
Query: 1056 QTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALK-FALYKKMTQAAILIQSKFRS 1114
Q RK++ R+ ++ + AA +IQ +R Y A+K A Y+K A I++QS +R
Sbjct: 1590 QAHVRKHQQRQKYKKMKKAAVIIQTHFRAYI----FAMKVLASYQKTRSAVIVLQSAYRG 1645
Query: 1115 YYEQKRFQQSRRAAVLIQQHYRSYRRRPGPPHRTSATLPARNKGSF-LTKKQDQAARKIM 1173
+K + + + IQ +YR+Y + +AT+ ++ T+KQ R
Sbjct: 1646 MQARKMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAA 1705
Query: 1174 RFLRRCRHRMRELKQNQE 1191
F+++C + Q +E
Sbjct: 1706 LFIQQCYRSKKIAAQKRE 1723
Score = 44.7 bits (104), Expect = 5e-04
Identities = 51/181 (28%), Positives = 82/181 (45%), Gaps = 31/181 (17%)
Query: 1040 LSDHEQRELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKY--KQLTWIALKFAL 1097
L H++RE +AAR+IQ A + ++ ++ AA VIQ+ +R+ ++ + K L
Sbjct: 1286 LKRHQERE--KAARIIQLAVINFLAKQRLRKRVNAALVIQKYWRRVLAQRKLLMLKKEKL 1343
Query: 1098 YKKMTQAAILIQSKFRSYYEQKRFQ---------QSRR--------------AAVLIQQH 1134
K +AA LIQ +R Y ++RF QSR A V IQ+H
Sbjct: 1344 EKVQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQSRIRMIIAVTSYKRYLWATVTIQRH 1403
Query: 1135 YRSYRRRPGPPHR----TSATLPARNKGSFLTKKQDQAARKIMRFLRRCRHRMRELKQNQ 1190
+R+Y RR R S+TL ++ +++ Q+ K L+R KQ +
Sbjct: 1404 WRAYLRRKQDQQRYEMLKSSTLIIQSMFRKWKQRKMQSQVKATVILQRAFREWHLRKQAK 1463
Query: 1191 E 1191
E
Sbjct: 1464 E 1464
Score = 44.7 bits (104), Expect = 5e-04
Identities = 33/121 (27%), Positives = 62/121 (51%), Gaps = 21/121 (17%)
Query: 1039 TLSDHEQRELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKY-----KQLTWIAL 1093
TL QR+ ++ A +IQ+ +R + ++ + + AA +IQ+ YR Y + ++
Sbjct: 1962 TLRRQLQRQ-HKCAIIIQSYYRMHVQQKKWKIMKKAALLIQKYYRAYSIGREQNHLYLKT 2020
Query: 1094 KFALY---------------KKMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSY 1138
K A+ K +AA+ IQSK+R+Y +K++ R +A++IQ+ YR
Sbjct: 2021 KAAVVTLQSAYRGMKVRKRIKDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGI 2080
Query: 1139 R 1139
+
Sbjct: 2081 K 2081
Score = 43.9 bits (102), Expect = 0.001
Identities = 35/147 (23%), Positives = 68/147 (46%), Gaps = 9/147 (6%)
Query: 1049 YEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALKFALYKKMTQAAILI 1108
+ AA +IQ +R YKGR++ +Q+ AA +IQ+ R + +K+ +KK T +++
Sbjct: 3030 HRAACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRAREAGKHERIKYIEFKKST---VIL 3086
Query: 1109 QSKFRSYYEQKRFQQSRRAAVLIQQHYRSYRRRPGPPHRTSATLPARNKGSFLTKKQDQA 1168
Q+ R + +KRF + R L+ +Y H + + K K ++
Sbjct: 3087 QALVRGWLVRKRFLEQRAKIRLLHFTAAAYY------HLNAVRIQRAYKLYLAVKNANKQ 3140
Query: 1169 ARKIMRFLRRCRHRMRELKQNQELEGL 1195
++ R R R++E + Q+ +
Sbjct: 3141 VNSVICIQRWFRARLQEKRFIQKYHSI 3167
Score = 43.1 bits (100), Expect = 0.002
Identities = 29/88 (32%), Positives = 49/88 (55%), Gaps = 8/88 (9%)
Query: 1051 AARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALKFALYKKMTQAAILIQS 1110
AA +Q AFR+ K L Q AA VIQ +R + ++F KK I Q+
Sbjct: 1540 AAIQLQAAFRRLKAHNLCRQIR-AACVIQSYWRMRQD----RVRFLNLKK---TIIKFQA 1591
Query: 1111 KFRSYYEQKRFQQSRRAAVLIQQHYRSY 1138
R + +++++++ ++AAV+IQ H+R+Y
Sbjct: 1592 HVRKHQQRQKYKKMKKAAVIIQTHFRAY 1619
Score = 43.1 bits (100), Expect = 0.002
Identities = 28/98 (28%), Positives = 51/98 (52%), Gaps = 5/98 (5%)
Query: 1046 RELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALKFALYKKMTQAA 1105
RE++ AA IQ+ FR ++ + + A+ VIQ+ Y+ + L+ Y + +A
Sbjct: 2332 REMHRAATFIQSTFRMHRLHMRYQALKQASVVIQQQYQANRAAK---LQRQHYLRQRHSA 2388
Query: 1106 ILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRS--YRRR 1141
+++Q+ FR ++ + +A LIQ +RS RRR
Sbjct: 2389 VILQAAFRGMKTRRHLKSMHSSATLIQSRFRSLLVRRR 2426
Score = 42.7 bits (99), Expect = 0.002
Identities = 27/96 (28%), Positives = 47/96 (48%), Gaps = 3/96 (3%)
Query: 1046 RELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALKFALYKKMTQAA 1105
++ +AA IQ+ +R YK ++ +A +IQR YR K + Y + + A
Sbjct: 2041 KDCNKAAVTIQSKYRAYKTKKKYATYRASAIIIQRWYRGIKITNH---QHKEYLNLKKTA 2097
Query: 1106 ILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYRRR 1141
I IQS +R ++ Q RAA I+ ++ ++ R
Sbjct: 2098 IKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSR 2133
Score = 42.4 bits (98), Expect = 0.003
Identities = 44/163 (26%), Positives = 75/163 (46%), Gaps = 39/163 (23%)
Query: 1046 RELYEAARVIQTAFRKYKGRR-LKEQQE-------------------------VAAAVIQ 1079
R+ AAR+IQT +RKYK + LK QE AA VIQ
Sbjct: 1264 RKEIRAARLIQTTWRKYKLKTDLKRHQEREKAARIIQLAVINFLAKQRLRKRVNAALVIQ 1323
Query: 1080 RCYRKY--KQLTWIALKFALYKKMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYR- 1136
+ +R+ ++ + K L K +AA LIQ +R Y ++RF + + ++++Q R
Sbjct: 1324 KYWRRVLAQRKLLMLKKEKLEKVQNKAASLIQGYWRRYSTRQRFLKLKYYSIILQSRIRM 1383
Query: 1137 -----SYRRRPGPPHRTSATLPARNKGSFLTKKQDQAARKIMR 1174
SY+R + + R+ ++L +KQDQ ++++
Sbjct: 1384 IIAVTSYKR-----YLWATVTIQRHWRAYLRRKQDQQRYEMLK 1421
Score = 42.4 bits (98), Expect = 0.003
Identities = 34/111 (30%), Positives = 55/111 (49%), Gaps = 19/111 (17%)
Query: 1048 LYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKY----KQLTWIALKFALYK---- 1099
++ AA +IQ FR RR + A +IQR YR + L ++ ++ A+ K
Sbjct: 2262 MHIAATLIQRRFRTLMMRRRFLSLKKTAILIQRKYRAHLCTKHHLQFLQVQNAVIKIQSS 2321
Query: 1100 -----------KMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYR 1139
+M +AA IQS FR + R+Q ++A+V+IQQ Y++ R
Sbjct: 2322 YRRWMIRKRMREMHRAATFIQSTFRMHRLHMRYQALKQASVVIQQQYQANR 2372
Score = 41.6 bits (96), Expect = 0.005
Identities = 28/102 (27%), Positives = 49/102 (48%), Gaps = 3/102 (2%)
Query: 1040 LSDHEQRELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALKFALYK 1099
+S E L A +Q+ + + R+ AA IQ+CYR K A K Y
Sbjct: 1670 VSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIA---AQKREEYM 1726
Query: 1100 KMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYRRR 1141
+M ++ I +Q+ R Y +K+ + R+A + +Q ++R + R
Sbjct: 1727 QMRESCIKLQAFVRGYLVRKQMRLQRKAVISLQSYFRMRKAR 1768
Score = 41.6 bits (96), Expect = 0.005
Identities = 38/156 (24%), Positives = 75/156 (48%), Gaps = 15/156 (9%)
Query: 1038 LTLSDHEQRE---LYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALK 1094
+ +++H+ +E L + A IQ+ +R + RR + AA I+ ++ ++
Sbjct: 2080 IKITNHQHKEYLNLKKTAIKIQSVYRGIRVRRHIQHMHRAATFIKAMFKMHQSRI----- 2134
Query: 1095 FALYKKMTQAAILIQSKFRSYYEQK----RFQQSRRAAVLIQQHYRSYR-RRPGPPHRTS 1149
Y M +AAI+IQ + R+YY+ K ++ +A ++Q +R R RR +T+
Sbjct: 2135 --SYHTMRKAAIVIQVRCRAYYQGKMQREKYLTILKAVKVLQASFRGVRVRRTLRKMQTA 2192
Query: 1150 ATLPARNKGSFLTKKQDQAARKIMRFLRRCRHRMRE 1185
ATL N + + +KI + +++ M+E
Sbjct: 2193 ATLIQSNYRRYRQQTYFNKLKKITKTVQQRYWAMKE 2228
Score = 41.2 bits (95), Expect = 0.006
Identities = 23/91 (25%), Positives = 49/91 (53%), Gaps = 3/91 (3%)
Query: 1051 AARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALKFALYKKMTQAAILIQS 1110
AA +Q FR ++ R+ AA V+Q YR + + +Y ++ + I+IQ+
Sbjct: 2862 AAITLQHYFRTWQTRKQFLLYRKAAVVLQNHYRAFLSAKH---QRQVYLQIRSSVIIIQA 2918
Query: 1111 KFRSYYEQKRFQQSRRAAVLIQQHYRSYRRR 1141
+ + + ++++FQ+ + + + IQ +R YR +
Sbjct: 2919 RSKGFIQKRKFQEIKNSTIKIQAMWRRYRAK 2949
Score = 40.8 bits (94), Expect = 0.008
Identities = 28/87 (32%), Positives = 41/87 (47%), Gaps = 3/87 (3%)
Query: 1055 IQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALKFALYKKMTQAAILIQSKFRS 1114
+Q+ FR K R+ + A VIQ Y YK F KK AA +Q+ +R
Sbjct: 1758 LQSYFRMRKARQYYLKMYKAIIVIQNYYHAYKAQVNQRKNFLQVKK---AATCLQAAYRG 1814
Query: 1115 YYEQKRFQQSRRAAVLIQQHYRSYRRR 1141
Y ++ +Q AA+ IQ +R Y +R
Sbjct: 1815 YKVRQLIKQQSIAALKIQSAFRGYNKR 1841
Score = 40.0 bits (92), Expect = 0.013
Identities = 33/118 (27%), Positives = 53/118 (44%), Gaps = 15/118 (12%)
Query: 1043 HEQRELYE----AARVIQTAFRKY----KGRRLKEQQEVAAAVIQRCYRKYKQLTWIALK 1094
H+QR+ Y+ AA +IQT FR Y K ++ A V+Q YR +
Sbjct: 1596 HQQRQKYKKMKKAAVIIQTHFRAYIFAMKVLASYQKTRSAVIVLQSAYRGMQAR------ 1649
Query: 1095 FALYKKMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYRRRPGPPHRTSATL 1152
+Y + + I IQS +R+Y +K F + A + +Q + + R H +A L
Sbjct: 1650 -KMYIHILTSVIKIQSYYRAYVSKKEFLSLKNATIKLQSTVKMKQTRKQYLHLRAAAL 1706
Score = 40.0 bits (92), Expect = 0.013
Identities = 43/160 (26%), Positives = 73/160 (45%), Gaps = 17/160 (10%)
Query: 1035 FALLTLSDHEQRELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKY-KQLTWIAL 1093
FA+ L+ +++ A V+Q+A+R + R++ + IQ YR Y + +++L
Sbjct: 1621 FAMKVLASYQKTR--SAVIVLQSAYRGMQARKMYIHILTSVIKIQSYYRAYVSKKEFLSL 1678
Query: 1094 KFALYKKMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRS-----YRRRPGPPHRT 1148
K A I +QS + +K++ R AA+ IQQ YRS +R R
Sbjct: 1679 K--------NATIKLQSTVKMKQTRKQYLHLRAAALFIQQCYRSKKIAAQKREEYMQMRE 1730
Query: 1149 SATLPARNKGSFLTKKQDQAARKIMRFLRRCRHRMRELKQ 1188
S +L +KQ + RK + L + RMR+ +Q
Sbjct: 1731 SCIKLQAFVRGYLVRKQMRLQRKAVISL-QSYFRMRKARQ 1769
Score = 37.7 bits (86), Expect = 0.066
Identities = 28/94 (29%), Positives = 48/94 (51%), Gaps = 1/94 (1%)
Query: 1044 EQRELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALKFALYKKMTQ 1103
E + +A ++IQ F R +A +IQR +R IA + L K +
Sbjct: 2973 EYLAILKAVKIIQGCFYTKLERTRFLNVRASAIIIQRKWRAILPAK-IAHEHFLMIKRHR 3031
Query: 1104 AAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRS 1137
AA LIQ+ +R Y ++ F + + AA++IQ++ R+
Sbjct: 3032 AACLIQAHYRGYKGRQVFLRQKSAALIIQKYIRA 3065
Score = 36.6 bits (83), Expect = 0.15
Identities = 25/107 (23%), Positives = 52/107 (48%), Gaps = 19/107 (17%)
Query: 1054 VIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKY------------KQLTWIALKFALYK-- 1099
+IQ FR ++ ++L ++++ + IQ+ Y+ Y K+ I L+ A +
Sbjct: 1493 IIQKRFRCFQAQKLYKRRKESILTIQKYYKAYLKGKIERTNYLQKRAAAIQLQAAFRRLK 1552
Query: 1100 -----KMTQAAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYRRR 1141
+ +AA +IQS +R ++ RF ++ + Q H R +++R
Sbjct: 1553 AHNLCRQIRAACVIQSYWRMRQDRVRFLNLKKTIIKFQAHVRKHQQR 1599
Score = 34.3 bits (77), Expect = 0.73
Identities = 39/176 (22%), Positives = 73/176 (41%), Gaps = 31/176 (17%)
Query: 1046 RELYEAARVIQTAFRKYKGRRLKEQQEVAAAVIQRCYRKYKQLTWIALKFALYKKMTQ-- 1103
+ ++ AA +IQ+ +R ++ + E ++ A VIQ YR Y ++ F +K +
Sbjct: 2686 QNMHRAATLIQSFYRMHRAKVDYETKKTAIVVIQNYYRLYVRVKTERKNFLAVQKSVRTI 2745
Query: 1104 ---------------------AAILIQSKFRSYYEQKRFQQSRRAAVLIQQHYRSYR--- 1139
AAI+ QS Y + +++ + V+IQ+ Y++
Sbjct: 2746 QAAFRGMKVRQKLKNVSEEKMAAIVNQSALCCYRSKTQYEAVQSEGVMIQEWYKASGLAC 2805
Query: 1140 RRPGPPHRTSATLPARNKG--SFLTKK---QDQAARKIMRFLRRCRHRMRELKQNQ 1190
+ H S K +T+K Q AA +I FL+ +R R ++Q +
Sbjct: 2806 SQEAEYHSQSRAAVTIQKAFCRMVTRKLETQKCAALRIQFFLQMAVYRRRFVQQKR 2861
>gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo
sapiens]
Length = 305
Score = 57.0 bits (136), Expect = 1e-07
Identities = 60/238 (25%), Positives = 90/238 (37%), Gaps = 46/238 (19%)
Query: 250 ISPKVEPRALTLTSI---PHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLE 306
+SP +EP A +L + P P P P A PP +P +P+ + + ++ A P+
Sbjct: 104 VSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVA 163
Query: 307 IRPSPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVVGTEPSA 366
+ P AP P P+ + A V P+
Sbjct: 164 VAVLAP--------------------------------APAPAPAPAPAPAPVAAPAPAP 191
Query: 367 PPAP---PSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQA 423
PAP P+PA PD +PQ G QG P A+ H+ S PAA A
Sbjct: 192 APAPAPAPAPAPAPDA---APQESAEQGANQGQRGQEPLADQLHSGISG-RPAAG-TAAA 246
Query: 424 AARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPPPSPPPSPAPLEPSSR 481
+A G + ++G + F + + E+ G P P P PS P +E + R
Sbjct: 247 SANGAAIKKLSGPLISDFFAKRKRSAPEKSSGD---VPAPCPSPSAAPGVGSVEQTPR 301
Score = 37.0 bits (84), Expect = 0.11
Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 11/89 (12%)
Query: 460 PPIPSPPPSPPPSPAPLEPSSRVGRGEALFGGPVGASELEPFSLSS-FPDLMGELISDEA 518
PP+P P+P P+PAP+ A PV + L P + P ++ A
Sbjct: 138 PPVPVLAPAPAPAPAPVA---------APVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPA 188
Query: 519 PSIPAPTPQLSPALSTITDFSPEWSYPEG 547
P+ PAP P +PA + D +P+ S +G
Sbjct: 189 PA-PAPAPAPAPAPAPAPDAAPQESAEQG 216
Score = 33.1 bits (74), Expect = 1.6
Identities = 20/63 (31%), Positives = 28/63 (44%)
Query: 809 LEELQRQEPSVEPPFALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPDGSPPPAP 868
LEE Q PSV P S P P + +P+ ++ + + AP +P PAP
Sbjct: 118 LEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAP 177
Query: 869 LPA 871
PA
Sbjct: 178 APA 180
Score = 31.2 bits (69), Expect = 6.2
Identities = 40/156 (25%), Positives = 52/156 (33%), Gaps = 25/156 (16%)
Query: 350 PRPSMSLAVVVGTEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTP 409
PRP +AV V P PA S D +P++ P P A TP
Sbjct: 95 PRP---VAVAVAVSPPLEPAAESL----DGLEEAPEQ----------LPSVPVPAPASTP 137
Query: 410 CSALEPAAALEPQAAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAP---PIPSPP 466
P L P A A P P + + + AP P P+P
Sbjct: 138 ----PPVPVLAP-APAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPA 192
Query: 467 PSPPPSPAPLEPSSRVGRGEALFGGPVGASELEPFS 502
P+P P+PAP + A G G EP +
Sbjct: 193 PAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLA 228
>gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo
sapiens]
Length = 305
Score = 57.0 bits (136), Expect = 1e-07
Identities = 60/238 (25%), Positives = 90/238 (37%), Gaps = 46/238 (19%)
Query: 250 ISPKVEPRALTLTSI---PHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLE 306
+SP +EP A +L + P P P P A PP +P +P+ + + ++ A P+
Sbjct: 104 VSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVA 163
Query: 307 IRPSPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVVGTEPSA 366
+ P AP P P+ + A V P+
Sbjct: 164 VAVLAP--------------------------------APAPAPAPAPAPAPVAAPAPAP 191
Query: 367 PPAP---PSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQA 423
PAP P+PA PD +PQ G QG P A+ H+ S PAA A
Sbjct: 192 APAPAPAPAPAPAPDA---APQESAEQGANQGQRGQEPLADQLHSGISG-RPAAG-TAAA 246
Query: 424 AARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPPPSPPPSPAPLEPSSR 481
+A G + ++G + F + + E+ G P P P PS P +E + R
Sbjct: 247 SANGAAIKKLSGPLISDFFAKRKRSAPEKSSGD---VPAPCPSPSAAPGVGSVEQTPR 301
Score = 37.0 bits (84), Expect = 0.11
Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 11/89 (12%)
Query: 460 PPIPSPPPSPPPSPAPLEPSSRVGRGEALFGGPVGASELEPFSLSS-FPDLMGELISDEA 518
PP+P P+P P+PAP+ A PV + L P + P ++ A
Sbjct: 138 PPVPVLAPAPAPAPAPVA---------APVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPA 188
Query: 519 PSIPAPTPQLSPALSTITDFSPEWSYPEG 547
P+ PAP P +PA + D +P+ S +G
Sbjct: 189 PA-PAPAPAPAPAPAPAPDAAPQESAEQG 216
Score = 33.1 bits (74), Expect = 1.6
Identities = 20/63 (31%), Positives = 28/63 (44%)
Query: 809 LEELQRQEPSVEPPFALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPDGSPPPAP 868
LEE Q PSV P S P P + +P+ ++ + + AP +P PAP
Sbjct: 118 LEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAP 177
Query: 869 LPA 871
PA
Sbjct: 178 APA 180
Score = 31.2 bits (69), Expect = 6.2
Identities = 40/156 (25%), Positives = 52/156 (33%), Gaps = 25/156 (16%)
Query: 350 PRPSMSLAVVVGTEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTP 409
PRP +AV V P PA S D +P++ P P A TP
Sbjct: 95 PRP---VAVAVAVSPPLEPAAESL----DGLEEAPEQ----------LPSVPVPAPASTP 137
Query: 410 CSALEPAAALEPQAAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAP---PIPSPP 466
P L P A A P P + + + AP P P+P
Sbjct: 138 ----PPVPVLAP-APAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPA 192
Query: 467 PSPPPSPAPLEPSSRVGRGEALFGGPVGASELEPFS 502
P+P P+PAP + A G G EP +
Sbjct: 193 PAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLA 228
>gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo
sapiens]
Length = 316
Score = 57.0 bits (136), Expect = 1e-07
Identities = 60/238 (25%), Positives = 90/238 (37%), Gaps = 46/238 (19%)
Query: 250 ISPKVEPRALTLTSI---PHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLE 306
+SP +EP A +L + P P P P A PP +P +P+ + + ++ A P+
Sbjct: 115 VSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVA 174
Query: 307 IRPSPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVVGTEPSA 366
+ P AP P P+ + A V P+
Sbjct: 175 VAVLAP--------------------------------APAPAPAPAPAPAPVAAPAPAP 202
Query: 367 PPAP---PSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQA 423
PAP P+PA PD +PQ G QG P A+ H+ S PAA A
Sbjct: 203 APAPAPAPAPAPAPDA---APQESAEQGANQGQRGQEPLADQLHSGISG-RPAAG-TAAA 257
Query: 424 AARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPPPSPPPSPAPLEPSSR 481
+A G + ++G + F + + E+ G P P P PS P +E + R
Sbjct: 258 SANGAAIKKLSGPLISDFFAKRKRSAPEKSSGD---VPAPCPSPSAAPGVGSVEQTPR 312
Score = 37.0 bits (84), Expect = 0.11
Identities = 27/89 (30%), Positives = 41/89 (46%), Gaps = 11/89 (12%)
Query: 460 PPIPSPPPSPPPSPAPLEPSSRVGRGEALFGGPVGASELEPFSLSS-FPDLMGELISDEA 518
PP+P P+P P+PAP+ A PV + L P + P ++ A
Sbjct: 149 PPVPVLAPAPAPAPAPVA---------APVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPA 199
Query: 519 PSIPAPTPQLSPALSTITDFSPEWSYPEG 547
P+ PAP P +PA + D +P+ S +G
Sbjct: 200 PA-PAPAPAPAPAPAPAPDAAPQESAEQG 227
Score = 33.1 bits (74), Expect = 1.6
Identities = 20/63 (31%), Positives = 28/63 (44%)
Query: 809 LEELQRQEPSVEPPFALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPDGSPPPAP 868
LEE Q PSV P S P P + +P+ ++ + + AP +P PAP
Sbjct: 129 LEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAP 188
Query: 869 LPA 871
PA
Sbjct: 189 APA 191
Score = 31.2 bits (69), Expect = 6.2
Identities = 40/156 (25%), Positives = 52/156 (33%), Gaps = 25/156 (16%)
Query: 350 PRPSMSLAVVVGTEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTP 409
PRP +AV V P PA S D +P++ P P A TP
Sbjct: 106 PRP---VAVAVAVSPPLEPAAESL----DGLEEAPEQ----------LPSVPVPAPASTP 148
Query: 410 CSALEPAAALEPQAAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAP---PIPSPP 466
P L P A A P P + + + AP P P+P
Sbjct: 149 ----PPVPVLAP-APAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPA 203
Query: 467 PSPPPSPAPLEPSSRVGRGEALFGGPVGASELEPFS 502
P+P P+PAP + A G G EP +
Sbjct: 204 PAPAPAPAPAPAPDAAPQESAEQGANQGQRGQEPLA 239
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 55.5 bits (132), Expect = 3e-07
Identities = 129/566 (22%), Positives = 181/566 (31%), Gaps = 114/566 (20%)
Query: 256 PRALTLTSIPHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLEIRPSPPTSR 315
P L L PP+ P A PP+ SP +SS +P P
Sbjct: 634 PLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATP------ 687
Query: 316 GGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQADPRPSMSL---AVVVGTEPSAPPAPPS 372
TAIL L+ L R P + P +S+ +V P+ PAP +
Sbjct: 688 -------TAILTQDSLQM---FLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPAT 737
Query: 373 PAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPPPQS 432
P G G+ P P+++A+ P + AA L +GP P S
Sbjct: 738 PV----------------AKGAGLGPQAPDSQASPAPAPQIPAAAPL------KGPGPSS 775
Query: 433 VAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPPPSPPPSPAPLEPSSRVGRGEALFGGP 492
S G +P +PSP P+ PPS P P S V R P
Sbjct: 776 --------------SPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQS-VSR-------P 813
Query: 493 VGASELEPF-SLSSFPDLMGELISDEAPSIPAPTPQLSPAL--STITDFSPEWSYPEGGV 549
L P + P L G + +P P +P P+ PEG
Sbjct: 814 PSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEG-- 871
Query: 550 KVLITGPWTEAAEHYSCVFDHIAVPASLVQP-------------GVLRCYCPAHEVGLVS 596
L P + S V + L P G + P + LV
Sbjct: 872 -PLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVP 930
Query: 597 LQVAGREGPLSASVLFEYRARRFLSLPSTQLDWLSLDDNQFRMSILERLEQMEKRMAEIA 656
A P F+ F +LP + ++LER Q+ +
Sbjct: 931 EPAAPPPPPPRT---FQMVTTPFPALPQPK-------------ALLERFHQVPSGIILQN 974
Query: 657 AAGQVPCQGPDAPPVQDEGQGPGFEARVVVLVESMIPRSTWKGPERLAHGSPFRGMSLLH 716
AG P A P GP VLV P T P +P L
Sbjct: 975 KAGGAP-----AAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGLPP 1029
Query: 717 LAAAQ--GYARLIETLSQWRSVETG-----SLDLEQEVDPLNVDHFSCTPLMWACALGHL 769
L A+ +A + TL+ ++ +G L E ++ L + P AC L HL
Sbjct: 1030 LLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPP-TLQPSKEACFLEHL 1088
Query: 770 ---EAAVLLFRWNRQALSIPDSLGRL 792
+ +VL + S D+L RL
Sbjct: 1089 HKHQGSVLHPDYKTAFPSFEDALHRL 1114
Score = 49.7 bits (117), Expect = 2e-05
Identities = 66/277 (23%), Positives = 101/277 (36%), Gaps = 42/277 (15%)
Query: 277 APLPPELPKAHTSPSSSSSSSSSGFAEPLEIRPSPPTSRGGSSRGGTAILLLTGLEQRAG 336
AP+ P P S ++ S ++P P+ T G + +A+ +L
Sbjct: 545 APIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLN------- 597
Query: 337 GLTPTRHLAPQADPRPSMSLAVVVGTEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGV 396
TP + P A P + A V T AP APP+ + L PQ Q
Sbjct: 598 --TPDGLVQP-ATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQ-------- 646
Query: 397 SPDFPEAEAAHTPCSAL---EPAAALEPQAAARGPPPQSVAGG---RRGNCFFIQDDDSG 450
P P +AA P + P A P+ G PP + + F+ + S
Sbjct: 647 PPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQ 706
Query: 451 EELKGHGAAPPIP------SPPPSPPPSPA----------PLEPSSRVGRGEALFGGPVG 494
+ L G +P +PPP+ P+PA P P S+ A
Sbjct: 707 QPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPA--PQIPA 764
Query: 495 ASELEPFSLSSFPDLMGELISDEAPSIPAPTPQLSPA 531
A+ L+ SS P L + ++P +P+P P P+
Sbjct: 765 AAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPS 801
Score = 42.7 bits (99), Expect = 0.002
Identities = 83/318 (26%), Positives = 111/318 (34%), Gaps = 56/318 (17%)
Query: 262 TSIPHAHPPEPPPLIAPL---------PPELPKAHTSPSSSSSSSSSGFAEPL---EIRP 309
+S P A PP L L P + A S S SSSSSSS A L E P
Sbjct: 1229 SSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGP 1288
Query: 310 SPPTSRG--GSSRGGTAILLLTGLEQRAGGLTPTRH---LAPQADPRPSMSLAVVVGTEP 364
P +R + + I L ++Q A GL+ H L P P P + + V P
Sbjct: 1289 MPSRNRPPIKTYEARSRIGLKLKIKQEA-GLSKVVHNTALDPVHQPPPPPA-TLKVAEPP 1346
Query: 365 SAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALE--PQ 422
PP PP P + ++ P G +P P T + A E P
Sbjct: 1347 PRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPA 1406
Query: 423 AAARGPPP-------QSVAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPPPSPPPSPAP 475
ARG P G ++D+ LKG PPP PA
Sbjct: 1407 GRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKG-------------PPPEPA- 1452
Query: 476 LEPSSRVGRGEALFGGPVGASELEPFS--LSSFPDLMGELISDEAPSIPAPTPQLSPALS 533
S+ G G+ + P L P S PD+ S ++P T L A+
Sbjct: 1453 --ASAAQGTGDPDWEAP----GLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAID 1506
Query: 534 TITDF------SPEWSYP 545
+I + +P SYP
Sbjct: 1507 SILNLQQAPGRTPAPSYP 1524
Score = 40.8 bits (94), Expect = 0.008
Identities = 57/229 (24%), Positives = 76/229 (33%), Gaps = 53/229 (23%)
Query: 252 PKVEPRALTLTSIPHAHPPEPPPL---------IAPLPPELPKAHTSPSSSSSSSSSGFA 302
P P L + P PP PPP P PE T+P +
Sbjct: 1333 PPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYR 1392
Query: 303 EPLEIRPSPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQAD-----------PR 351
E + +P + G +RGG+ L +++ GL R LA D P
Sbjct: 1393 ENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGL--IRELAAVEDELYQRMLKGPPPE 1450
Query: 352 PSMSLAVVVG----TEPSAPPA----PPSPAFDPDRFLNSPQRGQT-------------- 389
P+ S A G P PPA SP D F + + T
Sbjct: 1451 PAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILN 1510
Query: 390 --YGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPPPQSVAGG 436
G+ +P +P A +A TP S P P+A PP S GG
Sbjct: 1511 LQQAPGRTPAPSYPHAASAGTPAS---PPPLHRPEAY----PPSSHNGG 1552
Score = 33.9 bits (76), Expect = 0.96
Identities = 32/112 (28%), Positives = 43/112 (38%), Gaps = 30/112 (26%)
Query: 817 PSVEPPFALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPDGSPPPAPLPASEMTM 876
P EPP PP +P T G F + + G PPPA PA
Sbjct: 813 PPSEPPLHPCPPPQAPPT-----------LPGIFVIQNQL-----GVPPPASNPA----- 851
Query: 877 EDMAPGQLSSGVPEAPLLLMDYEATNSKGPLSSLPALPPASDDGAAPEDADS 928
APG P+ PL ++ +GPL P LPP+S A +++
Sbjct: 852 -PTAPGP-----PQPPL---RPQSQPPEGPLPPAPHLPPSSTSSAVASSSET 894
>gi|122937321 UNC homeobox [Homo sapiens]
Length = 531
Score = 55.1 bits (131), Expect = 4e-07
Identities = 63/220 (28%), Positives = 88/220 (40%), Gaps = 40/220 (18%)
Query: 264 IPHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLEIRPSPPTSRGGSSRGGT 323
+P A P L++ PP A S +++++++ FA L P +G
Sbjct: 326 LPKASPFSVESLLSDSPPRRKAA--SNAAAAAAAGLDFAPGLPCAPRTLIGKGH------ 377
Query: 324 AILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVVGTEPSAPPAPPSPAFDPDRFLNS 383
LL + Q G L P L A G EP+ APP+PA P +
Sbjct: 378 --FLLYPITQPLGFLVPQAALKGGA------------GLEPAPKDAPPAPAVPP-----A 418
Query: 384 PQRGQTYGG--GQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPPPQSVAGGRRGNC 441
P ++G G G +PD A A +P + P A A R + G G+C
Sbjct: 419 PPAQASFGAFSGPGGAPD--SAFARRSPDAVASPGAPAPAPAPFRDLASAAATEGGGGDC 476
Query: 442 FFIQDDDSGEELKGHGAAPPIPSPPPSP-PPSPAPLEPSS 480
D+G G PP PSP P P PPSPA EP++
Sbjct: 477 A-----DAGTA--GPAPPPPAPSPRPGPRPPSPAE-EPAT 508
Score = 39.7 bits (91), Expect = 0.017
Identities = 84/358 (23%), Positives = 112/358 (31%), Gaps = 94/358 (26%)
Query: 217 PTKPAPRTHACLCSGGLGSGSLTHKCSSTKHRIISPKVEPRALTLTSIPHAHPPEPPPLI 276
P +PA +H CSG + K K E + L H H P L
Sbjct: 170 PGRPAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRKHEKKLLKSQG-RHLHSPGGLSL- 227
Query: 277 APLPPELPKAHTSPSSSSSSSSSGFA-EPLEIRPSPPTSRG----GSSRGGTAILLLTGL 331
H++PSS S S G + EP E P PP ++G S GTA G
Sbjct: 228 ----------HSAPSSDSDSGGGGLSPEPPE--PPPPAAKGPGAHASGAAGTA-PAPPGE 274
Query: 332 EQRAG----GLTPTRHLAPQADPRPSMSL----------AVVVGTEPSAPPAPPSPAFDP 377
G P++ PRP A V E A P + F
Sbjct: 275 PPAPGTCDPAFYPSQRSGAGPQPRPGRPADKDAASCGPGAAVAAVERGAAGLPKASPFSV 334
Query: 378 DRFL-NSPQRGQTYGGGQGVSP---DFPEAEAAHTPCS--------------ALEPAAAL 419
+ L +SP R + + DF A PC+ +P L
Sbjct: 335 ESLLSDSPPRRKAASNAAAAAAAGLDF----APGLPCAPRTLIGKGHFLLYPITQPLGFL 390
Query: 420 EPQAAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPPPSPPPSPAPLEPS 479
PQAA +G G G P PP+P PAP +
Sbjct: 391 VPQAALKG---------------------------GAGLEPAPKDAPPAPAVPPAPPAQA 423
Query: 480 SRVGRGEALFGGPVGASELEPFSLSSFPDLMGELISDEAPSIPAPTPQLSPALSTITD 537
S F GP GA + S+F + ++ PAP P A + T+
Sbjct: 424 S-----FGAFSGPGGAPD------SAFARRSPDAVASPGAPAPAPAPFRDLASAAATE 470
Score = 37.4 bits (85), Expect = 0.087
Identities = 34/131 (25%), Positives = 45/131 (34%), Gaps = 14/131 (10%)
Query: 817 PSVEPPFALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPDGSPPPAPLP------ 870
P PP PP+ + S P D F+ S + A G+P PAP P
Sbjct: 406 PKDAPPAPAVPPAPPAQASFGAFSGPGGAPDSAFARRSPDAVASPGAPAPAPAPFRDLAS 465
Query: 871 --ASEMTMEDMAPGQLSSGVPEAPLLLMDYEATNSKGPLSSLPALPPASDDGAAPEDADS 928
A+E D A + P P + GP PA PA+ P A
Sbjct: 466 AAATEGGGGDCADAGTAGPAPPPP------APSPRPGPRPPSPAEEPATCGVPEPGAAAG 519
Query: 929 PQAVDVIPVDM 939
P + +DM
Sbjct: 520 PSPPEGEELDM 530
Score = 32.0 bits (71), Expect = 3.6
Identities = 42/182 (23%), Positives = 58/182 (31%), Gaps = 67/182 (36%)
Query: 381 LNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPPPQSVAGGRRGN 440
L+S + GG G+SP+ PE P AA+GP +
Sbjct: 227 LHSAPSSDSDSGGGGLSPEPPEP-----------------PPPAAKGPGAHASGAA---- 265
Query: 441 CFFIQDDDSGEELKGHGAAPPIPSPPPSPPPSPAPLEPSSRVGRG--------------- 485
G AP P PP+P PS R G G
Sbjct: 266 ----------------GTAPAPPGEPPAPGTCDPAFYPSQRSGAGPQPRPGRPADKDAAS 309
Query: 486 -------EALFGGPVGASELEPFSLSSFPDLMGELISDEAPSIPAPTPQLSPALSTITDF 538
A+ G G + PFS+ S L+SD P A + + A + + DF
Sbjct: 310 CGPGAAVAAVERGAAGLPKASPFSVES-------LLSDSPPRRKAASNAAAAAAAGL-DF 361
Query: 539 SP 540
+P
Sbjct: 362 AP 363
>gi|149158696 HLA-B associated transcript-3 isoform b [Homo sapiens]
Length = 1126
Score = 53.9 bits (128), Expect = 9e-07
Identities = 72/304 (23%), Positives = 103/304 (33%), Gaps = 37/304 (12%)
Query: 269 PPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLEIRPSPPTSRGG----SSRGGTA 324
PP P AP P + +PSS++ SS+ A P P P TS S +
Sbjct: 388 PPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEP 447
Query: 325 ILLLTGLEQRAG---GLTPTRHLAPQADPRPSMSLAVVVGTEPSAP-----PAPPSPAFD 376
++++ Q +G G P+ P P +L V P+AP P P
Sbjct: 448 VVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQAR 507
Query: 377 PDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPPPQSVAGG 436
P P G G G G + + + ++P + PP + A
Sbjct: 508 PSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASA 567
Query: 437 RRGNCFFIQDDDSGEELKGHGAAPPIPS-PPPSPPPSPAPLEPSSRVGRGEALFGGPVGA 495
G + G AP P+ PPP+P PS A L+ S +G G G
Sbjct: 568 SAG---------TTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAGG 618
Query: 496 SELE-----------PFSLSSFPDLMGELISDEAPSIPAPTPQLSPALSTITDFSPEWSY 544
S + P L D + + P P P P +P T+ P
Sbjct: 619 SGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTM----PPPGS 674
Query: 545 PEGG 548
P GG
Sbjct: 675 PSGG 678
Score = 48.5 bits (114), Expect = 4e-05
Identities = 73/268 (27%), Positives = 93/268 (34%), Gaps = 29/268 (10%)
Query: 248 RIISPKVEPRALTLTSIPHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGF-AEPLE 306
RI VEP + +I + AP P P H + GF P
Sbjct: 439 RISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGH---GQTLGQQVPGFPTAPTR 495
Query: 307 I---RPSPPTSR----GGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVV 359
+ RP+PP +R GG GT L GL A L Q +P + V
Sbjct: 496 VVIARPTPPQARPSHPGGPPVSGT--LQGAGLGTNASLAQMVSGLVGQLLMQPVL---VA 550
Query: 360 VGTEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSAL-----E 414
GT APP P+ A N+ GG P P+ A S L
Sbjct: 551 QGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLG 610
Query: 415 PAAALEPQAAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPPPSPPPSP- 473
PA P A G ++ G F+Q + L+ APP P PPP PPP+P
Sbjct: 611 PAG---PGAGGSGVASPTITVAMPGVPAFLQG--MTDFLQATQTAPPPPPPPPPPPPAPE 665
Query: 474 -APLEPSSRVGRGEALFGGPVGASELEP 500
+ P G GG +G L P
Sbjct: 666 QQTMPPPGSPSGGAGSPGG-LGLESLSP 692
Score = 32.7 bits (73), Expect = 2.1
Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 8/75 (10%)
Query: 457 GAAPPIPSPPPSPPP-SPAPLEPSSRVG---RGEALFGGPVGASELEPFSLSSFPDLMGE 512
G P PPP PP +P P+ SS+ EA P+ A E+E + + P E
Sbjct: 188 GPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNP----E 243
Query: 513 LISDEAPSIPAPTPQ 527
L AP+ P P P+
Sbjct: 244 LTPGPAPAGPTPAPE 258
>gi|18375632 HLA-B associated transcript-3 isoform b [Homo sapiens]
Length = 1126
Score = 53.9 bits (128), Expect = 9e-07
Identities = 72/304 (23%), Positives = 103/304 (33%), Gaps = 37/304 (12%)
Query: 269 PPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLEIRPSPPTSRGG----SSRGGTA 324
PP P AP P + +PSS++ SS+ A P P P TS S +
Sbjct: 388 PPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEP 447
Query: 325 ILLLTGLEQRAG---GLTPTRHLAPQADPRPSMSLAVVVGTEPSAP-----PAPPSPAFD 376
++++ Q +G G P+ P P +L V P+AP P P
Sbjct: 448 VVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQAR 507
Query: 377 PDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPPPQSVAGG 436
P P G G G G + + + ++P + PP + A
Sbjct: 508 PSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASA 567
Query: 437 RRGNCFFIQDDDSGEELKGHGAAPPIPS-PPPSPPPSPAPLEPSSRVGRGEALFGGPVGA 495
G + G AP P+ PPP+P PS A L+ S +G G G
Sbjct: 568 SAG---------TTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAGG 618
Query: 496 SELE-----------PFSLSSFPDLMGELISDEAPSIPAPTPQLSPALSTITDFSPEWSY 544
S + P L D + + P P P P +P T+ P
Sbjct: 619 SGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTM----PPPGS 674
Query: 545 PEGG 548
P GG
Sbjct: 675 PSGG 678
Score = 48.5 bits (114), Expect = 4e-05
Identities = 73/268 (27%), Positives = 93/268 (34%), Gaps = 29/268 (10%)
Query: 248 RIISPKVEPRALTLTSIPHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGF-AEPLE 306
RI VEP + +I + AP P P H + GF P
Sbjct: 439 RISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGH---GQTLGQQVPGFPTAPTR 495
Query: 307 I---RPSPPTSR----GGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVV 359
+ RP+PP +R GG GT L GL A L Q +P + V
Sbjct: 496 VVIARPTPPQARPSHPGGPPVSGT--LQGAGLGTNASLAQMVSGLVGQLLMQPVL---VA 550
Query: 360 VGTEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSAL-----E 414
GT APP P+ A N+ GG P P+ A S L
Sbjct: 551 QGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLG 610
Query: 415 PAAALEPQAAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPPPSPPPSP- 473
PA P A G ++ G F+Q + L+ APP P PPP PPP+P
Sbjct: 611 PAG---PGAGGSGVASPTITVAMPGVPAFLQG--MTDFLQATQTAPPPPPPPPPPPPAPE 665
Query: 474 -APLEPSSRVGRGEALFGGPVGASELEP 500
+ P G GG +G L P
Sbjct: 666 QQTMPPPGSPSGGAGSPGG-LGLESLSP 692
Score = 32.7 bits (73), Expect = 2.1
Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 8/75 (10%)
Query: 457 GAAPPIPSPPPSPPP-SPAPLEPSSRVG---RGEALFGGPVGASELEPFSLSSFPDLMGE 512
G P PPP PP +P P+ SS+ EA P+ A E+E + + P E
Sbjct: 188 GPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNP----E 243
Query: 513 LISDEAPSIPAPTPQ 527
L AP+ P P P+
Sbjct: 244 LTPGPAPAGPTPAPE 258
>gi|18375630 HLA-B associated transcript-3 isoform b [Homo sapiens]
Length = 1126
Score = 53.9 bits (128), Expect = 9e-07
Identities = 72/304 (23%), Positives = 103/304 (33%), Gaps = 37/304 (12%)
Query: 269 PPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLEIRPSPPTSRGG----SSRGGTA 324
PP P AP P + +PSS++ SS+ A P P P TS S +
Sbjct: 388 PPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEP 447
Query: 325 ILLLTGLEQRAG---GLTPTRHLAPQADPRPSMSLAVVVGTEPSAP-----PAPPSPAFD 376
++++ Q +G G P+ P P +L V P+AP P P
Sbjct: 448 VVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQAR 507
Query: 377 PDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPPPQSVAGG 436
P P G G G G + + + ++P + PP + A
Sbjct: 508 PSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASA 567
Query: 437 RRGNCFFIQDDDSGEELKGHGAAPPIPS-PPPSPPPSPAPLEPSSRVGRGEALFGGPVGA 495
G + G AP P+ PPP+P PS A L+ S +G G G
Sbjct: 568 SAG---------TTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAGG 618
Query: 496 SELE-----------PFSLSSFPDLMGELISDEAPSIPAPTPQLSPALSTITDFSPEWSY 544
S + P L D + + P P P P +P T+ P
Sbjct: 619 SGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTM----PPPGS 674
Query: 545 PEGG 548
P GG
Sbjct: 675 PSGG 678
Score = 48.5 bits (114), Expect = 4e-05
Identities = 73/268 (27%), Positives = 93/268 (34%), Gaps = 29/268 (10%)
Query: 248 RIISPKVEPRALTLTSIPHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGF-AEPLE 306
RI VEP + +I + AP P P H + GF P
Sbjct: 439 RISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGH---GQTLGQQVPGFPTAPTR 495
Query: 307 I---RPSPPTSR----GGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVV 359
+ RP+PP +R GG GT L GL A L Q +P + V
Sbjct: 496 VVIARPTPPQARPSHPGGPPVSGT--LQGAGLGTNASLAQMVSGLVGQLLMQPVL---VA 550
Query: 360 VGTEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSAL-----E 414
GT APP P+ A N+ GG P P+ A S L
Sbjct: 551 QGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLG 610
Query: 415 PAAALEPQAAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPPPSPPPSP- 473
PA P A G ++ G F+Q + L+ APP P PPP PPP+P
Sbjct: 611 PAG---PGAGGSGVASPTITVAMPGVPAFLQG--MTDFLQATQTAPPPPPPPPPPPPAPE 665
Query: 474 -APLEPSSRVGRGEALFGGPVGASELEP 500
+ P G GG +G L P
Sbjct: 666 QQTMPPPGSPSGGAGSPGG-LGLESLSP 692
Score = 32.7 bits (73), Expect = 2.1
Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 8/75 (10%)
Query: 457 GAAPPIPSPPPSPPP-SPAPLEPSSRVG---RGEALFGGPVGASELEPFSLSSFPDLMGE 512
G P PPP PP +P P+ SS+ EA P+ A E+E + + P E
Sbjct: 188 GPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNP----E 243
Query: 513 LISDEAPSIPAPTPQ 527
L AP+ P P P+
Sbjct: 244 LTPGPAPAGPTPAPE 258
>gi|149158692 HLA-B associated transcript-3 isoform a [Homo sapiens]
Length = 1132
Score = 53.9 bits (128), Expect = 9e-07
Identities = 72/304 (23%), Positives = 103/304 (33%), Gaps = 37/304 (12%)
Query: 269 PPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLEIRPSPPTSRGG----SSRGGTA 324
PP P AP P + +PSS++ SS+ A P P P TS S +
Sbjct: 394 PPPTPNAEAPPPGPGQASSVAPSSTNVESSAEGAPPPGPAPPPATSHPRVIRISHQSVEP 453
Query: 325 ILLLTGLEQRAG---GLTPTRHLAPQADPRPSMSLAVVVGTEPSAP-----PAPPSPAFD 376
++++ Q +G G P+ P P +L V P+AP P P
Sbjct: 454 VVMMHMNIQDSGTQPGGVPSAPTGPLGPPGHGQTLGQQVPGFPTAPTRVVIARPTPPQAR 513
Query: 377 PDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPPPQSVAGG 436
P P G G G G + + + ++P + PP + A
Sbjct: 514 PSHPGGPPVSGTLQGAGLGTNASLAQMVSGLVGQLLMQPVLVAQGTPGMAPPPAPATASA 573
Query: 437 RRGNCFFIQDDDSGEELKGHGAAPPIPS-PPPSPPPSPAPLEPSSRVGRGEALFGGPVGA 495
G + G AP P+ PPP+P PS A L+ S +G G G
Sbjct: 574 SAG---------TTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLGPAGPGAGG 624
Query: 496 SELE-----------PFSLSSFPDLMGELISDEAPSIPAPTPQLSPALSTITDFSPEWSY 544
S + P L D + + P P P P +P T+ P
Sbjct: 625 SGVASPTITVAMPGVPAFLQGMTDFLQATQTAPPPPPPPPPPPPAPEQQTM----PPPGS 680
Query: 545 PEGG 548
P GG
Sbjct: 681 PSGG 684
Score = 48.5 bits (114), Expect = 4e-05
Identities = 73/268 (27%), Positives = 93/268 (34%), Gaps = 29/268 (10%)
Query: 248 RIISPKVEPRALTLTSIPHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGF-AEPLE 306
RI VEP + +I + AP P P H + GF P
Sbjct: 445 RISHQSVEPVVMMHMNIQDSGTQPGGVPSAPTGPLGPPGH---GQTLGQQVPGFPTAPTR 501
Query: 307 I---RPSPPTSR----GGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVV 359
+ RP+PP +R GG GT L GL A L Q +P + V
Sbjct: 502 VVIARPTPPQARPSHPGGPPVSGT--LQGAGLGTNASLAQMVSGLVGQLLMQPVL---VA 556
Query: 360 VGTEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSAL-----E 414
GT APP P+ A N+ GG P P+ A S L
Sbjct: 557 QGTPGMAPPPAPATASASAGTTNTATTAGPAPGGPAQPPPTPQPSMADLQFSQLLGNLLG 616
Query: 415 PAAALEPQAAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPPPSPPPSP- 473
PA P A G ++ G F+Q + L+ APP P PPP PPP+P
Sbjct: 617 PAG---PGAGGSGVASPTITVAMPGVPAFLQG--MTDFLQATQTAPPPPPPPPPPPPAPE 671
Query: 474 -APLEPSSRVGRGEALFGGPVGASELEP 500
+ P G GG +G L P
Sbjct: 672 QQTMPPPGSPSGGAGSPGG-LGLESLSP 698
Score = 31.2 bits (69), Expect = 6.2
Identities = 26/80 (32%), Positives = 36/80 (45%), Gaps = 9/80 (11%)
Query: 453 LKGHGAAPPIPSPPPSPPP--SPAPLEPSSRVG---RGEALFGGPVGASELEPFSLSSFP 507
L+ G P S PP PP +P P+ SS+ EA P+ A E+E + + P
Sbjct: 189 LQCRGGPQPQHSQPPPQPPAVTPEPVALSSQTSEPVESEAPPREPMEAEEVEERAPAQNP 248
Query: 508 DLMGELISDEAPSIPAPTPQ 527
EL AP+ P P P+
Sbjct: 249 ----ELTPGPAPAGPTPAPE 264
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 53.9 bits (128), Expect = 9e-07
Identities = 62/218 (28%), Positives = 76/218 (34%), Gaps = 20/218 (9%)
Query: 264 IPHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLEIRPSPPTSRGGSSRGGT 323
+P + PP PPP PLPP +P +PS P P+P S
Sbjct: 247 LPESLPP-PPPGGLPLPP-MPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPP 304
Query: 324 AILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVVGTEPSAPPA-PPSPAFDPDR-FL 381
A G+ A G+ P AP P S G P AP PP+P P +
Sbjct: 305 A----PGVHPPAPGVHPP---APGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGV 357
Query: 382 NSPQRGQTYGGGQGVSPD----FPEAEAAHTPCSALEPAA-ALEPQAAARGPPPQSVAGG 436
+ P G GV P P A A H + P A + PQA P P V
Sbjct: 358 HPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAPGMHPQAPGVHPQPPGVHPS 417
Query: 437 RRGNCFFIQDDDSGEELKGHGAAPPIPSPPPSPPPSPA 474
G + G G PP P PP PP P+
Sbjct: 418 APG----VHPQPPGVHPSNPGVHPPTPMPPMLRPPLPS 451
Score = 37.7 bits (86), Expect = 0.066
Identities = 26/97 (26%), Positives = 37/97 (38%), Gaps = 5/97 (5%)
Query: 453 LKGHGAAPPIPSPPPSPPPSPAPLEPSSRVGRGEALFGGPVGASELEPFSLSSFPDLMGE 512
+ G PP+P P PPP PL P G + GP G +L P + P
Sbjct: 238 MNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPS---GPPGPPQLPPPAPGVHPP--AP 292
Query: 513 LISDEAPSIPAPTPQLSPALSTITDFSPEWSYPEGGV 549
++ A + P P + P + +P P GV
Sbjct: 293 VVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGV 329
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 53.5 bits (127), Expect = 1e-06
Identities = 78/342 (22%), Positives = 123/342 (35%), Gaps = 85/342 (24%)
Query: 261 LTSIPHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLEIRPSPPTSRGGSSR 320
+T + PP PPP+ APLPP+ P +PL P+P +++
Sbjct: 755 ITQVAPPTPPPPPPIPAPLPPQAP-----------------PKPLVTIPAPTSTK----- 792
Query: 321 GGTAILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVVGTEPSAPPAPPSPAFDPDRF 380
T ++T +A TPT + P A +P+ + + P +PP PP P P
Sbjct: 793 --TVAPVVT----QAAPPTPTPPV-PPAKKQPAFPASYI----PPSPPTPPVPVPPP--- 838
Query: 381 LNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPPPQSVAGGRRGN 440
P++ ++ A P S L P ++ Q A++ PPP +
Sbjct: 839 -TLPKQ---------------QSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQP 882
Query: 441 CFFIQDDDSGEELKGHGAAP-------PIPSPP------------PSPPPSPAPLEPSSR 481
+ + + + A P P+PSP P PPPSP P P
Sbjct: 883 LKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPP- 941
Query: 482 VGRGEALFGGPVGASELEPFSLSSFPDLMGELISDEAPSIPAPTPQLSPALSTITDFSPE 541
P + P S P S P PTPQ + ++ + + E
Sbjct: 942 ----------PPPTASPTP-DKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSS--GAE 988
Query: 542 WSYPEGGVKVLITGPWTEAAEHYSCVFDHIAVPASLVQPGVL 583
P+ + +T AE S + + PA+ +PG L
Sbjct: 989 HPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKL 1030
Score = 50.8 bits (120), Expect = 8e-06
Identities = 71/283 (25%), Positives = 91/283 (32%), Gaps = 90/283 (31%)
Query: 254 VEPRALTLTSIPHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLEIRPSPPT 313
V P + S P PP PPP P PP P P S S+ S+G A P+ ++ S
Sbjct: 616 VTPYTASQPSPPLPPPPPPPPPPPPPPPPPP----PPLPSQSAPSAGSAAPMFVKYS--- 668
Query: 314 SRGGSSRGGTAILLLTGLEQRAGGL--TPTRHLAPQADPRPSMSLAVVVGTEPSAPPAPP 371
I L Q +G L PT + +P + L G P PP PP
Sbjct: 669 ----------TITRLQNASQHSGALFKPPTPPVMQSQSVKPQI-LVPPNGVVPPPPPPPP 717
Query: 372 SPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPPPQ 431
P +P A+ PC A PQ +A PP
Sbjct: 718 PP-----------------------TPGSAMAQLKPAPC------APSLPQFSAPPPP-- 746
Query: 432 SVAGGRRGNCFFIQDDDSGEELKGHGA---APPIPSPPPSPPPSPAPLEPSSRVGRGEAL 488
LK H P PP PPP PAPL P + +
Sbjct: 747 ---------------------LKIHQVQHITQVAPPTPPPPPPIPAPLPPQA-PPKPLVT 784
Query: 489 FGGPVGASELEPFSLSSFPDLMGELISDEAPSIPAPTPQLSPA 531
P + P +++ AP P PTP + PA
Sbjct: 785 IPAPTSTKTVAP------------VVTQAAP--PTPTPPVPPA 813
Score = 38.9 bits (89), Expect = 0.030
Identities = 60/264 (22%), Positives = 96/264 (36%), Gaps = 48/264 (18%)
Query: 214 DTHPTKPAPRTHACLCSGGLG-SGSLTHKCSSTKHRIISPKVEPRALTLTSIP--HAHPP 270
+T P AP L G+ G L C S K ++S + + + S P PP
Sbjct: 1016 ETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPP 1075
Query: 271 EPPPLIAPLPP-ELP---KAHTSPSSSSSSSSSGFAEPLEIRPSPPTSRGGSSRGGTAIL 326
PP PLPP E+P +TSP + + + ++ +PP +R R + L
Sbjct: 1076 PPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTR--PKRNDSTRL 1133
Query: 327 LLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVVGTEPSAPPAPPSPAFDPDRFLNSPQR 386
+ ++ T + PQ P SL+V P F D ++
Sbjct: 1134 TQAEISEQPTMAT----VVPQVPTSPKSSLSV-------------QPGFLADLNRTLQRK 1176
Query: 387 GQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPPPQSVAGGRRGNCFFIQD 446
T G + + S EP A ++ A PPP+ ++ ++
Sbjct: 1177 SITRHG------------SLSSRMSRAEPTATMDDMALP-PPPPELLSDQQKAGY----- 1218
Query: 447 DDSGEELKGHGAAPPIPSPPPSPP 470
G + G+ A PPP+PP
Sbjct: 1219 --GGSHISGY--ATLRRGPPPAPP 1238
Score = 35.8 bits (81), Expect = 0.25
Identities = 58/277 (20%), Positives = 91/277 (32%), Gaps = 50/277 (18%)
Query: 283 LPKAHTSPSSSSSSSSSGFAEPLEIRPSPPTSRGGSSRGGTAILLLTGLEQRAGGLT-PT 341
+P++ ++ S+ S S S +R S S L + R + P
Sbjct: 543 IPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMNRPY 602
Query: 342 RHLAPQADPRPSMSLAVVVGTEPSAP----PAPPSPAFDPDRFLNSPQRGQTYGGGQGVS 397
L P P+P + + ++PS P P PP P P P Q+ +
Sbjct: 603 TSLVPPLSPQPKI-VTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAA 661
Query: 398 PDFPEAEAAHTPCSALEPAAAL-----EPQAAARGPPPQSVAGGRRGNCFFIQDDDSGEE 452
P F + +A + + AL P ++ PQ +
Sbjct: 662 PMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQIL------------------- 702
Query: 453 LKGHGAAPPIPSPPPSPPP-------SPAPLEPSSRVGRGEALFGGPVGASELEPFSLSS 505
+ +G PP P PPP P P PAP PS P ++ P +
Sbjct: 703 VPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSL-----------PQFSAPPPPLKIHQ 751
Query: 506 FPDL--MGELISDEAPSIPAPTPQLSPALSTITDFSP 540
+ + P IPAP P +P +T +P
Sbjct: 752 VQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAP 788
Score = 32.7 bits (73), Expect = 2.1
Identities = 55/241 (22%), Positives = 80/241 (33%), Gaps = 28/241 (11%)
Query: 250 ISPKVEPRALTLTSIPHAHPPEPPPLIAPLPPELPKAHT-------SPSSSSSSSSSGFA 302
+ P + A + IP + P P P+ PP LPK + SP S S A
Sbjct: 810 VPPAKKQPAFPASYIPPSPPTPPVPV---PPPTLPKQQSFCAKPPPSPLSPVPSVVKQIA 866
Query: 303 EPLEIRPSPPTSRGGSSRGGTAILLLTG--LEQRAGGLTPTRHLAPQAD--PRPSMSLAV 358
P+PP + A + + P+ P D P P S V
Sbjct: 867 SQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLV 926
Query: 359 VVGTEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAA 418
PS PAPP P P +P + G G + P + ++
Sbjct: 927 FPPPPPSPVPAPPPP--PPPTASPTPDK----SGSPGKKTSKTSSPGGKKPPPTPQRNSS 980
Query: 419 LEPQAAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPPPSPPPSPAPLEP 478
++ + A P P+ + + F +SG K PPP+ PP P L
Sbjct: 981 IKSSSGAEHPEPKRPSVDSLVS-KFTPPAESGSPSKE-------TLPPPAAPPKPGKLNL 1032
Query: 479 S 479
S
Sbjct: 1033 S 1033
Score = 32.3 bits (72), Expect = 2.8
Identities = 35/139 (25%), Positives = 49/139 (35%), Gaps = 15/139 (10%)
Query: 819 VEPPFALSPPSSSPDTGLSSVS-SPSELSDGTFS----------VTSAYSSAPDGSPPPA 867
V PP PP +P + ++ + +P S FS V AP PPP
Sbjct: 708 VVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPP 767
Query: 868 PLPASEMTMEDMAPGQLSSGVPEAPLLLMDYEATNSKGPLSSLPALPPASDDGAAPEDAD 927
P+PA + AP + +P P + P +PPA A P
Sbjct: 768 PIPA---PLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYI 824
Query: 928 SPQ-AVDVIPVDMISLAKQ 945
P +PV +L KQ
Sbjct: 825 PPSPPTPPVPVPPPTLPKQ 843
Score = 31.6 bits (70), Expect = 4.7
Identities = 26/97 (26%), Positives = 35/97 (36%), Gaps = 4/97 (4%)
Query: 821 PPFALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPDGSPPPAPLPASEMTMEDMA 880
PP + PP+ + PS LS V S P PPP P PA E
Sbjct: 831 PPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFP---PPPTP-PAMESQPLKPV 886
Query: 881 PGQLSSGVPEAPLLLMDYEATNSKGPLSSLPALPPAS 917
P ++ P A ++ ++ P P PP S
Sbjct: 887 PANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPES 923
>gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens]
Length = 663
Score = 53.5 bits (127), Expect = 1e-06
Identities = 75/309 (24%), Positives = 97/309 (31%), Gaps = 45/309 (14%)
Query: 197 GNGTEEFSVEHLVQ----------QILDTHPTKPAPRTHACLCSGGLGSGSLTHKCSSTK 246
G T EH+ Q Q HP PA A G+GS + C
Sbjct: 85 GVATTPLGPEHMAQASTLGLSPPSQAFPAHPEAPAAAARAAALVAHPGAGS--YPCGGGS 142
Query: 247 HRIISPKVEPRALTLTSIPHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLE 306
P A L P PP PPP PP L T+ S SS G +
Sbjct: 143 SGAQPSAPPPPAPPLPPTPSPPPPPPPPP----PPALSGYTTTNSGGGGSSGKGHSRDFV 198
Query: 307 IRPSPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLA-VVVGTEPS 365
+R + ++ G + G EQR+G +P P +S + G + S
Sbjct: 199 LRRDLSATAPAAAMHGAPL----GGEQRSGTGSPQHPAPPPHSAGMFISASGTYAGPDGS 254
Query: 366 APPA--------PPSPAFDPDRFLNSPQRGQTYGG--------GQGVSPDFPEAEAAHTP 409
PA P +P P + G G+ P P + AH
Sbjct: 255 GGPALFPALHDTPGAPGGHPHPLNGQMRLGLAAAAAAAAAELYGRAEPPFAPRSGDAHYG 314
Query: 410 CSALEPAAALEPQAAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPPPSP 469
A AAAL A + A G L+ H A PP P PPP+P
Sbjct: 315 AVAAAAAAALHGYGAVNLNLNLAAAAAAAAA-------GPGPHLQHH-APPPAPPPPPAP 366
Query: 470 PPSPAPLEP 478
P P
Sbjct: 367 AQHPHQHHP 375
Score = 36.2 bits (82), Expect = 0.19
Identities = 29/88 (32%), Positives = 34/88 (38%), Gaps = 11/88 (12%)
Query: 408 TPCSALEPAAALEPQAAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPP- 466
+P S PA P AAAR + G C G +APP P+PP
Sbjct: 105 SPPSQAFPAHPEAPAAAARAAALVAHPGAGSYPC-------GGGSSGAQPSAPPPPAPPL 157
Query: 467 ---PSPPPSPAPLEPSSRVGRGEALFGG 491
PSPPP P P P + G GG
Sbjct: 158 PPTPSPPPPPPPPPPPALSGYTTTNSGG 185
>gi|18079216 CASK interacting protein 1 [Homo sapiens]
Length = 1431
Score = 53.1 bits (126), Expect = 2e-06
Identities = 55/180 (30%), Positives = 71/180 (39%), Gaps = 14/180 (7%)
Query: 265 PHAHPPEPPPL----IAPLPPELPKAHTSPSSSSSSSSSGFAEPL-EIRPSP-PTSRGGS 318
P P EPPP + PLPP +A P+ S +P+ +++ SP PTS+
Sbjct: 1193 PPPPPAEPPPTDLAHLPPLPPPEGEAR-KPAKPPVSPKPVLTQPVPKLQGSPTPTSKKVP 1251
Query: 319 SRGGTAILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVVGTEP-SAPPAP-PSPAFD 376
G + + +RA G P P P + V G SA P+P PSPA
Sbjct: 1252 LPGPGSPEV-----KRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQ 1306
Query: 377 PDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPPPQSVAGG 436
P L P G P P A A H P AAA AAA PP+ + G
Sbjct: 1307 PPAALAKPPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAPPEGASPG 1366
Score = 43.1 bits (100), Expect = 0.002
Identities = 65/273 (23%), Positives = 95/273 (34%), Gaps = 64/273 (23%)
Query: 256 PRALTLTSIPHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAE--PLEIRPS--- 310
P++L + +I PPEP P P + S ++ +G AE P +PS
Sbjct: 623 PQSLEVMAIESPPPPEPTPADCQSPKMTTFQDSELSDELQAAMTGPAEVGPTTEKPSSHL 682
Query: 311 PPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLA----------VVV 360
PPT R + + + L RA ++ ++ L P PS ++
Sbjct: 683 PPTPRATTRQDSS-------LGGRARHMSSSQELLGDGPPGPSSPMSRSQEYLLDEGPAP 735
Query: 361 GTEP---------------SAPPAPPSPA---------FDPDRFLNSPQRG--QTYGGGQ 394
GT P S PP P P F P + + G Q GG
Sbjct: 736 GTPPREARPGRHGHSIKRASVPPVPGKPRQVLPPGTSHFTPPQTPTKTRPGSPQALGGPH 795
Query: 395 GVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPPPQSVAGGRRGNCFFIQDDDSGEELK 454
G +P A+ TP + P++ + P RG + + GE
Sbjct: 796 GPAP--ATAKVKPTPQLLPPTERPMSPRSLPQSPT-------HRGFAYVLPQPVEGEV-- 844
Query: 455 GHGAAPPIPSPPPSPPPSPA---PLEPSSRVGR 484
G A P P+PPP P P P E + GR
Sbjct: 845 --GPAAPGPAPPPVPTAVPTLCLPPEADAEPGR 875
Score = 41.2 bits (95), Expect = 0.006
Identities = 39/156 (25%), Positives = 68/156 (43%), Gaps = 12/156 (7%)
Query: 821 PPFALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPDGSPPPAPLPASEMTMEDMA 880
PP + PP P T V + + L G+ + A S A PPA L T +
Sbjct: 1268 PPVSPKPPP--PPTAPKPVKAVAGLPSGSAGPSPAPSPARQ---PPAALAKPPGTPPSLG 1322
Query: 881 PGQLSSGVPEAPLLLMDYEATNSKGPLSSLPALPPASDDGAAPEDADSPQAVDVIPVDMI 940
P AP L + + + ++ A PPA +GA+P D+ + Q ++ +
Sbjct: 1323 ASPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAPPEGASPGDS-ARQKLE----ETS 1377
Query: 941 SLAKQIIEATPERIKREDFVGLPEAGASMRERTGAV 976
+ ++A E+I++ED G ++ A + TG++
Sbjct: 1378 ACLAAALQAVEEKIRQEDAQGPRDSAA--EKSTGSI 1411
Score = 40.0 bits (92), Expect = 0.013
Identities = 56/231 (24%), Positives = 73/231 (31%), Gaps = 53/231 (22%)
Query: 267 AHPPEPPPLIAPL-PPELPKAHTSPSSSSSSSSSGFAEPLEIRPSPPTSRGGSSRGGTAI 325
A PPE PP P PP AH P + A+P + P P
Sbjct: 1186 AGPPELPPPPPPAEPPPTDLAHLPPLPPPEGEARKPAKP-PVSPKP-------------- 1230
Query: 326 LLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVVGTEPSAPPAPPSPAFDPDRFLNSPQ 385
+L + + G TPT P P S + GT P P PP P +P+
Sbjct: 1231 VLTQPVPKLQGSPTPTSKKVPLPGPG-SPEVKRAHGTPPPVSPKPPPPP-------TAPK 1282
Query: 386 RGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPPPQSVAGGRRGNCFFIQ 445
+ G P A +P P+ A +P AA PP
Sbjct: 1283 PVKAVAG-------LPSGSAGPSPA----PSPARQPPAALAKPP---------------- 1315
Query: 446 DDDSGEELKGHGAAPPIPSPPPSPPPSPAPLEPSSRVGRGEALFGGPVGAS 496
+ L A PP P P P+ P ++ A P GAS
Sbjct: 1316 --GTPPSLGASPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAPPEGAS 1364
Score = 37.7 bits (86), Expect = 0.066
Identities = 32/102 (31%), Positives = 42/102 (41%), Gaps = 19/102 (18%)
Query: 715 LHLAAAQGYARLIETLSQWRSVETGSLDLEQEVDPLNVDHFSCTPLMWACALGHLEAAVL 774
LHLAA G+ + E L Q +S +P VD+ TPL AC G + L
Sbjct: 119 LHLAAQHGHYDVSEMLLQHQS------------NPCMVDNSGKTPLDLACEFGRVGVVQL 166
Query: 775 LFRWNRQALSI-------PDSLGRLPLSVAHSRGHVRLARCL 809
L N A + D G PL +A GH+ + R L
Sbjct: 167 LLSSNMCAALLEPRPGDATDPNGTSPLHLAAKNGHIDIIRLL 208
Score = 37.7 bits (86), Expect = 0.066
Identities = 46/194 (23%), Positives = 69/194 (35%), Gaps = 30/194 (15%)
Query: 364 PSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAAL-EPQ 422
P PP PP P + P + P PE EA + P L +P
Sbjct: 1189 PELPPPPPPAEPPPTDLAHLPP----------LPP--PEGEARKPAKPPVSPKPVLTQPV 1236
Query: 423 AAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPPPSPPPSPAPLEPSSRV 482
+G P + + S E + HG PP+ PP PP +P P++ + +
Sbjct: 1237 PKLQGSPTPT------SKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGL 1290
Query: 483 GRGEALFGGPVGASELEPFSLSSFPDLMGELISDEA--PS-------IPAPTPQLSPALS 533
G A + P +L+ P L + A PS +PA P+ + A +
Sbjct: 1291 PSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAAAAA 1350
Query: 534 TITDFSPEWSYPEG 547
P + PEG
Sbjct: 1351 AAAAAPP--APPEG 1362
Score = 34.3 bits (77), Expect = 0.73
Identities = 29/103 (28%), Positives = 47/103 (45%), Gaps = 13/103 (12%)
Query: 711 GMSLLHLAAAQGYARLIETLSQWRSVETGSLDLEQEVDPLNVDHFSCTPLMWACALGHLE 770
G S LH AA G LI L + ++ ++D++ D+ PL +A G E
Sbjct: 49 GFSALHHAALNGNTELISLLLEAQA----AVDIK--------DNKGMRPLHYAAWQGRKE 96
Query: 771 AAVLLFRWNRQALSIPDSLGRLPLSVAHSRGHVRLARCLEELQ 813
L+ + A++IP G +PL +A GH ++ L + Q
Sbjct: 97 PMKLVLKAG-SAVNIPSDEGHIPLHLAAQHGHYDVSEMLLQHQ 138
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 53.1 bits (126), Expect = 2e-06
Identities = 92/326 (28%), Positives = 118/326 (36%), Gaps = 40/326 (12%)
Query: 217 PTKPAPRTHACLCSGGLGSGSLTHKCSSTKHRIISPKVEPRALTLTSIPHAHPPEP--PP 274
P KP R + G S SLT CSS+ S + P+ LT PP P P
Sbjct: 610 PPKPE-RVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPA 668
Query: 275 LIAPLPPELPKA--HTSPSSSSSSSSSGFAEPLEIRP-SPPTSRGGSSRGGTAILLLTGL 331
+P PP P++ +P+ ++ + G + P SPPT + T + L
Sbjct: 669 PFSP-PPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQ-------TTLTPLQES 720
Query: 332 EQRAGGLTPTRHLAPQADPRPSMSLAVVVGTE-PSAPPAPPSPAFDPDRFLNSPQRGQTY 390
+ +P P P P + V E PSA P DP N P
Sbjct: 721 PVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDP----NWPPPPPPA 776
Query: 391 GGGQGVS-PDFPEAEAAHTPCSALEPAAALEPQAAARGPPPQSVAGGRRGNCFFIQDDDS 449
Q +S DFP E A ++ EPA P A IQ S
Sbjct: 777 PEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSP----AASSSSATALQIQPPGS 832
Query: 450 GEELKGHGAAPPIPSPPPSPPPSPAPLEPSSRVGRGEALFGGP----VGASELEPFSLSS 505
+ APP P+P S P A L VG + GGP VGA + P L
Sbjct: 833 PDP----PPAPPAPAPASSAPGHVAKLPQKEPVGCSKG--GGPPREDVGAPLVTPSLLQ- 885
Query: 506 FPDLMGELISDEAPSIPAPTPQLSPA 531
M L S AP APTP L P+
Sbjct: 886 ----MVRLRSVGAPG-GAPTPALGPS 906
Score = 52.0 bits (123), Expect = 3e-06
Identities = 79/356 (22%), Positives = 122/356 (34%), Gaps = 48/356 (13%)
Query: 217 PTKPAPRTHA-CLCSGGLGSGSLTHKCSSTKHRIISPKVEPRALTLTSIPHAHPPEPPPL 275
P AP A + G + + + + T ++P E ++ P PP PPP
Sbjct: 680 PNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSP---PPSPPPS 736
Query: 276 IAPLPP--ELPKAHTSPSSSSSSSSSGFAEPLEIRPSPPT------SRGGSSRGGTAILL 327
P PP + P+ S+S ++ +P P PP S A
Sbjct: 737 YHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFS 796
Query: 328 LTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVVGTEPSAPPAPPSPA---FDPDRFLNSP 384
+ E +P +P A + +L + P PPAPP+PA P P
Sbjct: 797 VASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLP 856
Query: 385 QRGQTYGGGQGVSPDFPEAEAAHTPCSALE-------------PAAALEPQAAARGPPPQ 431
Q+ + G +G P + A S L+ P AL P A P +
Sbjct: 857 QK-EPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSA-----PQK 910
Query: 432 SVAGGRRGNCFFIQDDDSG----EELKGHG--AAPPIPSPPPSPPPSPAPLEPSSRVGRG 485
+ G + SG LK A+ + S P+ PP P P S
Sbjct: 911 PLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTA 970
Query: 486 EALFGGPVGASELE-PFSLSSFPDLMGELISD-------EAPSIPAPTPQLSPALS 533
+F +LE P S + DL L+++ P P +P+ P ++
Sbjct: 971 SFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVA 1026
Score = 43.9 bits (102), Expect = 0.001
Identities = 72/311 (23%), Positives = 106/311 (34%), Gaps = 45/311 (14%)
Query: 232 GLGSGSLTHKCSSTKHRIISPKVEPRALTLTSIPHAHPPEPPPLIAPLPPELPKAHTSPS 291
G SG T + S T S ++ R+++L + PP PP L P
Sbjct: 462 GSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKR--PPPPPRRTHSLHQRGLAVPDGPL 519
Query: 292 SSSSSSSSGFAEPLEIRPSPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQADPR 351
L P PPT+ GGS G A GL+P P P
Sbjct: 520 GLPPKPERKQQPQL---PRPPTT-GGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPE 575
Query: 352 PSMSLAVVVGTEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCS 411
++S + ++ P PP P SP + Q P PE +
Sbjct: 576 RTLSPSSGYSSQSGTPTLPPKGLAGPPA---SPGKAQ---------PPKPERVTSLRSPG 623
Query: 412 ALEPAAALEPQAAARGPPPQSVAGGR----RGNCFFIQDDDSGEELKGHGAAPPIPSP-- 465
A ++ +++ P P +G + G+ F I P +P+P
Sbjct: 624 ASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPH------------PKVPAPFS 671
Query: 466 -PPSPPPSPAPLEPSSRVGRGEALFGGPVGASELEPFS-----LSSFPDLMGELISDEAP 519
PPS P SP P P+ A+ GPV ++ P S + P +IS +
Sbjct: 672 PPPSKPRSPNPAAPAL---AAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQS 728
Query: 520 SIPAPTPQLSP 530
P+P P P
Sbjct: 729 PPPSPPPSYHP 739
Score = 37.4 bits (85), Expect = 0.087
Identities = 36/122 (29%), Positives = 52/122 (42%), Gaps = 12/122 (9%)
Query: 815 QEPSVEPPFALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPDGSP----PPAPLP 870
+EP +P + PP + + LS P + FSV S + P GSP PA
Sbjct: 761 EEPLQDPNWPPPPPPAPEEQDLSMADFPPP-EEAFFSVASPEPAGPSGSPELVSSPAASS 819
Query: 871 ASEMTMEDMAPGQLSSGVPEAPLLLMDYEATNSKGPLSSLPALPP--ASDDGAAP-EDAD 927
+S ++ PG S P AP A+++ G ++ LP P S G P ED
Sbjct: 820 SSATALQIQPPG--SPDPPPAP--PAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVG 875
Query: 928 SP 929
+P
Sbjct: 876 AP 877
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 52.4 bits (124), Expect = 3e-06
Identities = 76/289 (26%), Positives = 96/289 (33%), Gaps = 52/289 (17%)
Query: 276 IAPLPPELPKA-------HTSPSSSSSSSSSGFAEPLEIRPS-----PPTSRGGSSRGGT 323
+AP PE+ A H S + ++ +G A P E P PP R GG
Sbjct: 43 LAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGP 102
Query: 324 AILLLTGLEQRAGGLTPTRHLAPQADPRPSMSL------------------AVVVGTEPS 365
QR G +P R L P P+ L AV G EP
Sbjct: 103 ---------QRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEP- 152
Query: 366 APPAPPSPAFDPDRFLNS-PQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAA 424
AP P PA + P G G G G P P A L +AAL
Sbjct: 153 APAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGA---AQTLNGSAALLNSHH 209
Query: 425 ARGPPPQSVAGGRRGNCFFIQDDDSGEELKGH----GAAPPIPSPPPSPPPSPAPLEPSS 480
A P V G + G ++ AAPP P+ P SPP +PAP P++
Sbjct: 210 AAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAP-SPPAAPAPAAPAA 268
Query: 481 R---VGRGEALFGGPVGASELEPFSLSSFPDLMGELISDEAPSIPAPTP 526
A P G P + + P A + PAP P
Sbjct: 269 APPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAP 317
Score = 40.4 bits (93), Expect = 0.010
Identities = 67/304 (22%), Positives = 105/304 (34%), Gaps = 41/304 (13%)
Query: 256 PRALTLTSIPHAHPPEPPPLIAPL---------PPELPKAHTSPSSSSSSSSSGFA-EPL 305
P A + P A PP PPP A L PP A P+++ + S+G A P
Sbjct: 257 PPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPA 316
Query: 306 EIRPSPPTSRGGSSRGGTAILLLTGLE----QRAGGLTPTRHLAPQADPRPSMSLAVVVG 361
P G G A G++ +R P A S + ++V+G
Sbjct: 317 PAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIG 376
Query: 362 TEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHT-------PCSALE 414
P+ A PSPA P +P G G V+ A T + L
Sbjct: 377 --PTMQGALPSPAAVPPPAPGTP-TGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLA 433
Query: 415 PAAALEPQAAA-----RGPPPQSVAGGRRGNCFFIQDDDSGE-ELKGHGAAPPIPSPPPS 468
P PQ + PP + G I + + + H +P P+
Sbjct: 434 PRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPA 493
Query: 469 PPPSPAPLEPSSRVGRGEALFGGPVGASELEPFSLSSFPDLMGELISDEAPSIPAPTPQL 528
P S P++ S+ G P+ A ++ P + ++ ++ + P+ T Q
Sbjct: 494 TPTSAPPVQISTVQAPGT-----PIIARQVTPTT------IIKQVSQAQTTVQPSATLQR 542
Query: 529 SPAL 532
SP +
Sbjct: 543 SPGV 546
Score = 34.7 bits (78), Expect = 0.56
Identities = 35/140 (25%), Positives = 54/140 (38%), Gaps = 10/140 (7%)
Query: 832 PDTGLSSVSSPSELSDGTFSVTSAYSSAPDGSPPPAPLPASEMTMEDMAPGQLSSGVPEA 891
P G ++ +P+ S +A ++AP PPP P PA+ PG +G P A
Sbjct: 242 PFVGAAAPPAPAAPSPPAAPAPAAPAAAP---PPPPPAPATLAR----PPGH-PAGPPTA 293
Query: 892 PLLLMDYEATNSKGPLSSLPALPPASDDGAAPEDADSPQAVDVIPVDMISL--AKQIIEA 949
+ A + G + PA PA+ A P A P + K++++A
Sbjct: 294 APAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQA 353
Query: 950 TPERIKREDFVGLPEAGASM 969
P + G ASM
Sbjct: 354 APPAAQTLAASGPASTAASM 373
Score = 32.0 bits (71), Expect = 3.6
Identities = 51/224 (22%), Positives = 64/224 (28%), Gaps = 60/224 (26%)
Query: 252 PKVEPRALTLTSIPHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLEIRPSP 311
PK + + P PP AP PP P A P P P
Sbjct: 229 PKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAP---------------AAPAAAPPPP 273
Query: 312 PTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLA--PQADPRPSMSLAVVVGTEPSAPPA 369
P + +R P H A P A P A G A PA
Sbjct: 274 PPAPATLAR-------------------PPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPA 314
Query: 370 PPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPP 429
P A GG GVS AA P ++ A P+ + P
Sbjct: 315 PAPAA----------------GGPAGVSGQPGPGAAAAAPAPGVK---AESPKRVVQAAP 355
Query: 430 PQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPPPSPPPSP 473
P + G G ++G +PSP PPP+P
Sbjct: 356 PAAQTLAASGPASTAASMVIGPTMQG-----ALPSPAAVPPPAP 394
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 52.4 bits (124), Expect = 3e-06
Identities = 76/283 (26%), Positives = 107/283 (37%), Gaps = 41/283 (14%)
Query: 269 PPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLEIRPSPPTSRGGSSRGGTAILLL 328
P PPP +PL P ++ TSP +S R SPP +S A+ L
Sbjct: 439 PLLPPPEESPLSPPPEESPTSPPPEAS------------RLSPPPEELPASPLPEALHLS 486
Query: 329 TGLEQRAGGLTPTRHLAPQADPRPSMSLAVVVGTEPSAPP--APPSPAFDPDRFLNSPQR 386
LE+ L+P +P + P P S + P +PP +PPSPA + L+ P
Sbjct: 487 RPLEE--SPLSPPPEESPLSPP-PESSPFSPLEESPLSPPEESPPSPALETP--LSPPPE 541
Query: 387 GQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPPPQSVAGGRRGNCFFIQD 446
+SP F E+ + P E + P+A+ PPP+ ++
Sbjct: 542 ASP------LSPPFEESPLSPPP---EELPTSPPPEASRLSPPPEESPMSPPP-----EE 587
Query: 447 DDSGEELKGHGAAPPIPSPPPSPPPSPAPLEPSSRVGRGEALFGGPVGASELEP---FSL 503
+ PP P SPPP +PL P R P S + P S
Sbjct: 588 SPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASR----LSPPPEDSPMSPPPEESP 643
Query: 504 SSFPDLMGELISDEAPSIPAPTPQLSPALSTITDFSPEWSYPE 546
S P + L S +P P+ SP LS + SP PE
Sbjct: 644 MSPPPEVSRLSPLPVVSRLSPPPEESP-LSPPPEESPTSPPPE 685
Score = 50.8 bits (120), Expect = 8e-06
Identities = 75/292 (25%), Positives = 100/292 (34%), Gaps = 43/292 (14%)
Query: 256 PRALTLTSIPHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSS-----SGFAEPLEIRPS 310
P L+ P P PPP + L P + TSP S +S S + PLE P
Sbjct: 666 PEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPL 725
Query: 311 PPTSRGGSSRGGTAILLLTGLEQRAGG--LTPTRHLAPQADPRPSMSLAVVVGTEPSAPP 368
P L R+ G L+P R P PRP EP P
Sbjct: 726 LPLPEEPQ------------LCPRSEGPHLSP-RPEEPHLSPRPEEPHLSPQAEEPHLSP 772
Query: 369 APPSPAF--DPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAAR 426
P P P+ SPQ G +S P+ E H EP + P+
Sbjct: 773 QPEEPCLCAVPEEPHLSPQ-----AEGPHLS---PQPEELHLSPQTEEPHLSPVPEEPCL 824
Query: 427 GPPPQS--VAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPPPSPPPSPAPLEPSSRVGR 484
P P+ ++ C + ++S +P + PP SP P P EP
Sbjct: 825 SPQPEESHLSPQSEEPCLSPRPEES-------HLSPELEKPPLSPRPEKPPEEPGQCPAP 877
Query: 485 GEALFGGPVGASELEPF----SLSSFPDLMGELISDEAPSIPAPTPQLSPAL 532
E P G L P +LS + + +E P P+ P LSP L
Sbjct: 878 EELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQL 929
Score = 50.4 bits (119), Expect = 1e-05
Identities = 77/285 (27%), Positives = 104/285 (36%), Gaps = 31/285 (10%)
Query: 273 PPLIAPLPPE---LPKAHTSPSSSSSSSSSGFAEPLEIRPSPPTSRGGSSRGGTAILLLT 329
P L APL E LP SP S S P R SPP +S A+ L
Sbjct: 428 PQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSR 487
Query: 330 GLEQRAGGLTPTRHLAPQADPRPSMSLAVVVGTEPSAPP--APPSPAFDPDRFLNSPQRG 387
LE+ L+P +P + P P S + P +PP +PPSPA + L+ P
Sbjct: 488 PLEESP--LSPPPEESPLSPP-PESSPFSPLEESPLSPPEESPPSPALETP--LSPPPEA 542
Query: 388 QTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPPPQS--VAGGRRGNCFFIQ 445
SP P E T + P+ + PPP+ ++ + F
Sbjct: 543 SPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPP 602
Query: 446 DDDSG-----EEL------KGHGAAPPIPSPPPSPPPSPAPLEPSSRVGRGEAL-----F 489
++S EE + +PP P SPPP +P+ P V R L
Sbjct: 603 FEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRL 662
Query: 490 GGPVGASELEP---FSLSSFPDLMGELISDEAPSIPAPTPQLSPA 531
P S L P S +S P L S +P P+ SPA
Sbjct: 663 SPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPA 707
Score = 43.9 bits (102), Expect = 0.001
Identities = 71/282 (25%), Positives = 95/282 (33%), Gaps = 55/282 (19%)
Query: 251 SPKVEPRALTLTSIPHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLEIRPS 310
SP L+ P A P PP +PL P + TSP +S S P E S
Sbjct: 526 SPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLS---PPPEESPMS 582
Query: 311 PPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVVGTEPSAPPAP 370
PP S A L E+ L+P +P + P + L+ P +PP
Sbjct: 583 PPPEESPMSPPPEASRLFPPFEE--SPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPE 640
Query: 371 PSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPPP 430
SP P R +SP P E+ +P P+ + PPP
Sbjct: 641 ESPMSPPPEV----SRLSPLPVVSRLSP--PPEESPLSP----------PPEESPTSPPP 684
Query: 431 QSVAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPPPSPPPSPAPLEPSSRVGRGEALFG 490
++ +PP P SPPP +P P ++L
Sbjct: 685 EA-----------------------SRLSPPPEDSPTSPPPEDSPASPPPE----DSLMS 717
Query: 491 GPVGASELEPFSLSSFPDLMGELISDEAPSI-PAP-TPQLSP 530
P+ S L P L P L E P + P P P LSP
Sbjct: 718 LPLEESPLLP--LPEEPQLCPR---SEGPHLSPRPEEPHLSP 754
Score = 43.1 bits (100), Expect = 0.002
Identities = 49/172 (28%), Positives = 63/172 (36%), Gaps = 32/172 (18%)
Query: 786 PDSLGRLPLSVAHSRGHVRLARCLEELQRQEPSVEPPFALSPPSSSPDTGL-SSVSSPSE 844
P+ L PL A + L+R LEE P E P + PP SSP + L S SP E
Sbjct: 471 PEELPASPLPEA-----LHLSRPLEESPLSPPPEESPLSP-PPESSPFSPLEESPLSPPE 524
Query: 845 LSDGTFSVTSAYSSAPDG------------SPPPAPLPAS-------------EMTMEDM 879
S + ++ + S P+ SPPP LP S E M
Sbjct: 525 ESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPP 584
Query: 880 APGQLSSGVPEAPLLLMDYEATNSKGPLSSLPALPPASDDGAAPEDADSPQA 931
S PEA L +E + P P PP +P DSP +
Sbjct: 585 PEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMS 636
Score = 42.7 bits (99), Expect = 0.002
Identities = 98/388 (25%), Positives = 123/388 (31%), Gaps = 86/388 (22%)
Query: 207 HLVQQILDTHPTKPAPRTHACLCSGGLGSGSLTHKCSSTKHRIISPKVEPRALT-LTSIP 265
HL Q + H P P CLC+ H + +SP+ E L+ T P
Sbjct: 760 HLSPQAEEPH-LSPQPE-EPCLCA----VPEEPHLSPQAEGPHLSPQPEELHLSPQTEEP 813
Query: 266 HAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAE----------PLEIRPSPPTSR 315
H P P ++P P E +H SP S S E PL RP P
Sbjct: 814 HLSPVPEEPCLSPQPEE---SHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEE 870
Query: 316 GGSSRGGTAILLLT-----GLEQRAGGLTPTRHLAPQADPRPSMSLAVVVGTEPSA---- 366
G + L L G + P P P L + EPS
Sbjct: 871 PGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPE-ELPLSPSGEPSLSPQL 929
Query: 367 -PPAPPSPAFDPDRFLNSPQRGQTYG------GGQGVS-PDFP-EAEAAHTPCSALEPAA 417
PP P P P +P G G +G S P+ P A TP S A
Sbjct: 930 MPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEAN 989
Query: 418 ALEPQAAARG--PPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPPPSPPPS--- 472
+P+ PP G L H P P PP+
Sbjct: 990 CTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPL 1049
Query: 473 --PAPLEPSSRVGRGEALFGGPVGASE-------------------LEPFSLSSFPDLMG 511
P+PL P +V VG S+ LEP + S P MG
Sbjct: 1050 SVPSPLSPIGKV----------VGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMG 1099
Query: 512 ELISDEAPSIPAPTPQLSPALSTITDFS 539
+L S PAP+P +PAL DFS
Sbjct: 1100 DL------SCPAPSP--APALD---DFS 1116
Score = 42.7 bits (99), Expect = 0.002
Identities = 79/307 (25%), Positives = 95/307 (30%), Gaps = 46/307 (14%)
Query: 255 EPRALTLTSIPHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLEIRPSPPTS 314
EP + PH P P ++P P EL H SP + S EP + P P S
Sbjct: 776 EPCLCAVPEEPHLSPQAEGPHLSPQPEEL---HLSPQTEEPHLSPVPEEPC-LSPQPEES 831
Query: 315 RGGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVVGTEPSAPPAPPS-P 373
L E HL+P+ + P EP PAP P
Sbjct: 832 H----------LSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELP 881
Query: 374 AFDPDRFLN-SPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAA------------LE 420
F P + SP G+ G P P E S EP+ + L
Sbjct: 882 LFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSG-EPSLSPQLMPPDPLPPPLS 940
Query: 421 PQAAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPP------PSP-PPSP 473
P A PP S G D D L PI PP P P PP
Sbjct: 941 PIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMI 1000
Query: 474 APLEPSSRVGRGEALFGGPVGASELEPFSLSSFPDLMGELISDEAPSIPAPTPQLSPALS 533
P P S V GP +EP P L L+ +P P L LS
Sbjct: 1001 LPPSPGSPV--------GPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPAL--PLS 1050
Query: 534 TITDFSP 540
+ SP
Sbjct: 1051 VPSPLSP 1057
Score = 42.7 bits (99), Expect = 0.002
Identities = 67/267 (25%), Positives = 95/267 (35%), Gaps = 78/267 (29%)
Query: 254 VEPRALTLTSIPHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLEIRPSPPT 313
+EPR T P +PP P P AP P + A + P G +P E +PP
Sbjct: 2185 LEPRFPTA---PPTYPPYPSPTGAPAQPPMLGASSRP---------GAGQPGEFHTTPP- 2231
Query: 314 SRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVVG------TEPSAP 367
GT R TP L P+ ++++ G +EP
Sbjct: 2232 --------GTP---------RHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLS 2274
Query: 368 PAP-----------------PSPAFDPDR--FLNSPQRGQTYGGGQGVSPDFPEAEAAHT 408
P P SP++ P F++SP G GG + +PD +A T
Sbjct: 2275 PPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPL--T 2332
Query: 409 PCSALEPAAALEPQAAARG------PPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPI 462
P A+ +EPQ+ G PP Q++A + + G + P
Sbjct: 2333 P-----RASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRP---GSYTDPYAQPPLT 2384
Query: 463 PSPPPSPP-------PSPAPLEPSSRV 482
P P P PP P P +P SRV
Sbjct: 2385 PRPQPPPPESCCALPPRSLPSDPFSRV 2411
Score = 41.2 bits (95), Expect = 0.006
Identities = 65/279 (23%), Positives = 90/279 (32%), Gaps = 69/279 (24%)
Query: 234 GSGSLTHKCSSTKHRIISPKVEPRALTL------TSIPHAHPPEPPPLIAPLPPELPKAH 287
G G K ST + + + P L T + P PP + LPP P
Sbjct: 2567 GPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSV--LPPPAPDGS 2624
Query: 288 TSPSSSSSSSSSGFAEPLEIRPSPPTSRG---------GSSRGGTAILLLTGLEQRAGGL 338
S +S SG P+E R P T G G+ G + L T LE++
Sbjct: 2625 LPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQ 2684
Query: 339 TPTRHLAPQADPRPSM--------SLAVVVGTEPSAPPAPPSPAFDPDRFLNSPQRGQTY 390
L Q R ++ + A VG S P SPAF+ RGQT
Sbjct: 2685 RLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFE------QLSRGQT- 2737
Query: 391 GGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPPPQSVAGGRRGNCFFIQDDDSG 450
P A + +++ G PP ++G G F DD
Sbjct: 2738 ------------------------PFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDD--- 2770
Query: 451 EELKGHGAAPPIPSPPPSPPPSPAPLEPSSRVGRGEALF 489
+ PPP PS + VG +A +
Sbjct: 2771 ----------RLSRPPPPATPSSMDVNSRQLVGGSQAFY 2799
Score = 37.0 bits (84), Expect = 0.11
Identities = 68/245 (27%), Positives = 85/245 (34%), Gaps = 44/245 (17%)
Query: 265 PHAHPPEPPPLIAPLPPELP-----KAHTSPSSSSSSSSSGFAEPLEIR---PSPPTSRG 316
P PP P A P LP + SP S SSS S PL PSP T R
Sbjct: 2385 PRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRF 2444
Query: 317 GSSRGGTAILLLTGLEQRAGGLTPTRHLAPQADPRP------SMSLA---VVVGTEPSAP 367
S + R P L P+P + SLA + G P+A
Sbjct: 2445 QSPDP------YSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAAL 2498
Query: 368 PAPPS-------PAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHT-----PCSALEP 415
PA P+ P+ P F+ SP G G + FP+A + P L P
Sbjct: 2499 PAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPP 2558
Query: 416 AAALEPQAAARGP---PPQS----VAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPPPS 468
+ GP PQS VA G SG + +G +P P P
Sbjct: 2559 PHGINSHFGP-GPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRP-PSVL 2616
Query: 469 PPPSP 473
PPP+P
Sbjct: 2617 PPPAP 2621
Score = 35.8 bits (81), Expect = 0.25
Identities = 61/221 (27%), Positives = 80/221 (36%), Gaps = 48/221 (21%)
Query: 332 EQRAGGLTPTRHLAPQADPRPSMSLAVVVGTEPSAPPAPPSPAFDPDRFLNSPQRGQTYG 391
E + T +A + D RP++ L + +P A +PP PA P F+ SP T
Sbjct: 2081 ESQINKQTKVGDIARKTD-RPALHLRIP--PQPGALGSPP-PAAAPTIFIGSP----TTP 2132
Query: 392 GGQGVSPDF---PEAEAAHTPCSALEPAAALEPQAAARGPPPQSVAGGRRGNCFFIQDDD 448
G S D P A + P S E L PQ A+ P D
Sbjct: 2133 AGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVP-----------------SQD 2175
Query: 449 SGEELKGHGAAPPIPSPPPSPPPSPAP---------LEPSSRVGRGE--ALFGGPVGA-- 495
+ P P+ PP+ PP P+P L SSR G G+ P G
Sbjct: 2176 PFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPR 2235
Query: 496 ---SELEPFSLSSFPDLMGELISDEAPSI---PAPTPQLSP 530
S +PF P L L E+P + A P LSP
Sbjct: 2236 HQPSTPDPFLKPRCPSL-DNLAVPESPGVGGGKASEPLLSP 2275
Score = 35.4 bits (80), Expect = 0.33
Identities = 35/133 (26%), Positives = 52/133 (39%), Gaps = 10/133 (7%)
Query: 821 PPFALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPDGSPPPAPLPASEMTMEDMA 880
PPF SP S P+ S +S P E S + + S P P +P P
Sbjct: 601 PPFEESPLSPPPEE--SPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPV 658
Query: 881 PGQLSSGVPEAPLLLMDYEATNSKGPLSSL--------PALPPASDDGAAPEDADSPQAV 932
+LS E+PL E+ S P +S P PP D A+P DS ++
Sbjct: 659 VSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSL 718
Query: 933 DVIPVDMISLAKQ 945
+ ++ L ++
Sbjct: 719 PLEESPLLPLPEE 731
Score = 33.1 bits (74), Expect = 1.6
Identities = 60/240 (25%), Positives = 81/240 (33%), Gaps = 60/240 (25%)
Query: 269 PPEPPPLIAPLPPELPKAHT-SPSSSS--SSSSSGFAEPLEIRPSPPTSRGGSSRGGTAI 325
PP+P L +P P P SP++ + S+S+ GF +P P S G G
Sbjct: 2107 PPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKP------PAGSVPGPDSPGELF 2160
Query: 326 LLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVVGTEPSAPPAPP------SPAFDPDR 379
L L P + P DP LA EP P APP SP P +
Sbjct: 2161 LKLPPQ-------VPAQ--VPSQDP---FGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQ 2208
Query: 380 FLNSPQRGQTYGGGQGVSPDF---PEAEAAHTPCSALEPAAALEPQAAARG----PPPQS 432
P G + G G +F P H P + P L+P+ + P
Sbjct: 2209 ---PPMLGASSRPGAGQPGEFHTTPPGTPRHQPST---PDPFLKPRCPSLDNLAVPESPG 2262
Query: 433 VAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSPPPSPPPSPAPLEPSSRVGRGEALFGGP 492
V GG+ A+ P+ SPPP A +G +G P
Sbjct: 2263 VGGGK--------------------ASEPLLSPPPFGESRKALEVKKEELGASSPSYGPP 2302
Score = 33.1 bits (74), Expect = 1.6
Identities = 45/157 (28%), Positives = 63/157 (40%), Gaps = 37/157 (23%)
Query: 370 PPSPAFDPDRFLNSPQRGQTYGGG------QGVSPD--------FPEAEAAHTPCSALEP 415
P SPA R P++G+ G G +G SPD F +T S L+
Sbjct: 4820 PESPA----RAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDI 4875
Query: 416 AAALEPQAAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPI-PSPPPSP---PP 471
+ L+ ++ A PP Q N +++ A PP PSPPPSP P
Sbjct: 4876 LSLLKQESPAPEPPTQHSYTYNVSNL----------DVRQLSAPPPEEPSPPPSPLAPSP 4925
Query: 472 SPAPLEPSSRVGRGEALFGGPVGASELEPFSLSSFPD 508
+ P EP + E L PV + P L+S P+
Sbjct: 4926 ASPPTEPLVELPT-EPLAEPPVPS----PLPLASSPE 4957
Score = 32.7 bits (73), Expect = 2.1
Identities = 39/123 (31%), Positives = 50/123 (40%), Gaps = 21/123 (17%)
Query: 816 EPSVEPPF-----ALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPDGSPPPAPLP 870
EP +E P L PP SP +S P E S TS A SPPP LP
Sbjct: 427 EPQLEAPLNEEMPLLPPPEESP------LSPPPEESP-----TSPPPEASRLSPPPEELP 475
Query: 871 ASEMTMEDMAPGQLSSGVPEAPLLLMDYEATNSKGPLSSLPALPPASDDGAAPEDADSPQ 930
AS + LS + E+PL E+ S P SS P P + PE++
Sbjct: 476 ASPLP----EALHLSRPLEESPLSPPPEESPLSPPPESS-PFSPLEESPLSPPEESPPSP 530
Query: 931 AVD 933
A++
Sbjct: 531 ALE 533
Score = 32.3 bits (72), Expect = 2.8
Identities = 33/133 (24%), Positives = 49/133 (36%), Gaps = 7/133 (5%)
Query: 819 VEPPFALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPDGSPPPAPLPASEMTMED 878
+ PPF SP S P+ S P E S + + S P P +P P +
Sbjct: 545 LSPPFEESPLSPPPEE--LPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPP 602
Query: 879 MAPGQLSSGVPEAPLLLMDYEATNSKGPLSSLPALPPASDDGAAPEDADSPQAVDVIPVD 938
LS E+P L EA+ P P PP + +P P+ + P+
Sbjct: 603 FEESPLSPPPEESP-LSPPPEASRLSPPPEDSPMSPPPEESPMSP----PPEVSRLSPLP 657
Query: 939 MISLAKQIIEATP 951
++S E +P
Sbjct: 658 VVSRLSPPPEESP 670
Score = 31.6 bits (70), Expect = 4.7
Identities = 47/176 (26%), Positives = 62/176 (35%), Gaps = 24/176 (13%)
Query: 217 PTKPAPRTHACLCSGGLGSGSLTHKCSSTKHRIISPKVEPRALTLTSIPHAHPPEPP--- 273
P+ P R A S LT + S + SP V PR + P++ PP P
Sbjct: 2404 PSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSP-VTPRFQSPD--PYSRPPSRPQSR 2460
Query: 274 ----PLIAPLPPELPKAHTSPSSSSSSS--SSGFAEPLEIRPSPPTSRGGSSRGGTAILL 327
PL P P+ P+ S + +S + GF L P+ S +
Sbjct: 2461 DPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVR 2520
Query: 328 LTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVVGTEPSAPPAPPSPAFDPDRFLNS 383
G G +P R PQA VG EPS P P P P +NS
Sbjct: 2521 SPGTGAFVGTPSPMRFTFPQA-----------VG-EPSLKPPVPQPGLPPPHGINS 2564
>gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]
Length = 984
Score = 52.4 bits (124), Expect = 3e-06
Identities = 53/193 (27%), Positives = 73/193 (37%), Gaps = 25/193 (12%)
Query: 251 SPKVEPRALTLTSIPHAHPPEPP-----PLIAPLPPELPKAHTSPSSSSSSSSSGFAEPL 305
+P + + T T +P A P PP P PL L K T PS S+G A
Sbjct: 300 TPPITQPSFTFT-LPAAAPASPPTSLLAPSTNPLLESLKKMQTPPSLPPCPESAGAATTE 358
Query: 306 EIRPSPPTSR----GGSSRGGTAILLLTGLEQRAG----GLTPTRHLAPQADPRPSMSLA 357
+ P S G S G +L + + GL P + P D + +L
Sbjct: 359 ALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQ 418
Query: 358 VVVGTEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAA 417
T+P A AP SPA P++ +G Q SP P A AA + +P
Sbjct: 419 AETATKPQATSAP-SPA---------PKQSFLFGT-QNTSPSSPAAPAASSAPPMFKPIF 467
Query: 418 ALEPQAAARGPPP 430
P++ GP P
Sbjct: 468 TAPPKSEKEGPTP 480
Score = 38.1 bits (87), Expect = 0.051
Identities = 36/130 (27%), Positives = 59/130 (45%), Gaps = 19/130 (14%)
Query: 817 PSVEPPFALSPPSSSPDTGLSSVSSPSELSDGTFSVTSAYSSAPDGSPPPAPLPASEMTM 876
P +P F + P+++P + +S+ +PS ++ + P S PP P A T
Sbjct: 302 PITQPSFTFTLPAAAPASPPTSLLAPS--TNPLLESLKKMQTPP--SLPPCPESAGAATT 357
Query: 877 EDMAPGQLSSGVP------EAPLLLMDYEATNSKGPLSSL-----PALPPASDDGAAP-- 923
E ++P + S +P P L+ + +SK P + L P++ PA+D A P
Sbjct: 358 EALSPPKTPSLLPPLGLSQSGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTL 417
Query: 924 --EDADSPQA 931
E A PQA
Sbjct: 418 QAETATKPQA 427
>gi|18959210 WIRE protein [Homo sapiens]
Length = 440
Score = 52.4 bits (124), Expect = 3e-06
Identities = 76/255 (29%), Positives = 96/255 (37%), Gaps = 44/255 (17%)
Query: 262 TSIPHAHPPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLEIRPS--PPTSRGGSS 319
T A PE P + P P+L + +T+ S+ SSS P R + PPT S
Sbjct: 138 TDSSRASLPELPRMQRPSLPDLSRPNTTSSTGMKHSSSAPPPPPPGRRANAPPTPLPMHS 197
Query: 320 RGGTAILLLTGLEQRAGG-LTPTRHLAPQADPRPSMSLAVVVGTEPS----APPAPP--- 371
A L G L P R P P V + T PS APP PP
Sbjct: 198 SKAPAYNREKPLPPTPGQRLHPGREGPPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQ 257
Query: 372 ---------SPAFD-----PDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAA 417
SP + P R NS R +T G +G++P P A+ + S P
Sbjct: 258 PPGVPNGPSSPTNESAPELPQRH-NSLHR-KTPGPVRGLAPP-PPTSASPSLLSNRPPPP 314
Query: 418 ALEP--QAAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPI---PSPPPS---- 468
A +P + AA PPP + G R + HG+ PP P PPPS
Sbjct: 315 ARDPPSRGAAPPPPPPVIRNGAR------DAPPPPPPYRMHGSEPPSRGKPPPPPSRTPA 368
Query: 469 --PPPSPAPLEPSSR 481
PPP P PL R
Sbjct: 369 GPPPPPPPPLRNGHR 383
Score = 40.0 bits (92), Expect = 0.013
Identities = 60/244 (24%), Positives = 83/244 (34%), Gaps = 51/244 (20%)
Query: 269 PPEPPPLIAPLPPELPKAHTSPSSSSSSSSSGFAEPLE--------------------IR 308
PP PPP P PP +A+T S G L+ I
Sbjct: 5 PPPPPPPGPPPPPTFHQANTEQPKLSRDEQRGRGALLQDICKGTKLKKVTNINDRSAPIL 64
Query: 309 PSPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHL-APQADPRPSMSLAVVVGTEPSAP 367
P S GG GG A+ GL Q GG+ R + A + A+ + + +A
Sbjct: 65 EKPKGSSGGYGSGGAALQPKGGLFQ--GGVLKLRPVGAKDGSENLAGKPALQIPSSRAAA 122
Query: 368 PAPP-SPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAAR 426
P PP S A + R + P P+ +T S ++ ++A
Sbjct: 123 PRPPVSAASGRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTTSS-----TGMKHSSSAP 177
Query: 427 GPPPQSVAGGRRGNC-------------FFIQD----DDSGEELKGHGAAPPIPSPPPSP 469
PPP GRR N + ++ G+ L PP P PP P
Sbjct: 178 PPPPP----GRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPGREGPPAP-PPVKP 232
Query: 470 PPSP 473
PPSP
Sbjct: 233 PPSP 236
>gi|188536004 zinc finger protein 469 [Homo sapiens]
Length = 3925
Score = 51.6 bits (122), Expect = 4e-06
Identities = 81/316 (25%), Positives = 108/316 (34%), Gaps = 77/316 (24%)
Query: 243 SSTKHRIISPKVEPRALTLTSIPHAHPPEPPPLIAPLPPELPKAHTSPSSS--------- 293
S TK + P+ L +P P+ P APL P LP+ P++
Sbjct: 127 SRTKPTLDETPENPQ-LEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQ 185
Query: 294 ---SSSSSSGFAEPLEIRPSPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQADP 350
SS +S+ + P P PP SRG + + + E +A G AD
Sbjct: 186 EPPSSFTSTNYTSP-SATPRPPAPGPPQSRGTSPLQPGSYPEYQASG----------ADS 234
Query: 351 RPSMSLAVVVGTEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEAAHTPC 410
P + G PPA P P P+ + G +GVS FP A H
Sbjct: 235 WPPAAENSFPGANFGVPPAEPEPI---------PKGSRPGGSPRGVSFQFP-FPALH--- 281
Query: 411 SALEPAAALEPQAAARGPPPQSVAGG--RRGNCFFIQDDDSG---EELKGHGAAPPIPSP 465
A+ P P VAG G F G EE G G A P+P+
Sbjct: 282 ------------GASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPT- 328
Query: 466 PPSPPPSPAPLEPSSRVGRGEALFGGPVGASELEPFSLSSFPDLMGELISDEAPSIPAPT 525
P PSP P + +P L+ DL G L S A + AP
Sbjct: 329 --QPAPSPLP-------------------CYQGQPGGLNRHSDLSGALSSPGA-AHSAPR 366
Query: 526 PQLSPALSTITDFSPE 541
P ++T PE
Sbjct: 367 PFSDSLHKSLTKILPE 382
Score = 37.4 bits (85), Expect = 0.087
Identities = 81/375 (21%), Positives = 118/375 (31%), Gaps = 118/375 (31%)
Query: 219 KPAPRTHACLCSGGLGSGSLTHKCSS-----------TKHRIISPKVEPRALTLTSIPHA 267
+P PR + + S G +L H CS T R + P P + +P
Sbjct: 3462 RPPPRGSSPILSEG-SLPALLHLCSEVAPSTTKGWPETLERPVDPVTHP--IRGCELPSN 3518
Query: 268 HPPEPPPLIAPLPPELPK---------AHTSPSSSSSSSSSG----FAEPLEIRPSPPTS 314
H PPP ++P P L A P + +S S G A PL P +
Sbjct: 3519 HQECPPPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPLLQQALPLGASLPRPGA 3578
Query: 315 RGGSSRGGTAILLLTGLEQRAGGL--------------------TPTRHLAPQADPR--- 351
RG + G A L+ +G ++RA G + H+ + PR
Sbjct: 3579 RGQDAEGKRAPLVFSG-KRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTF 3637
Query: 352 -----------------------PSMSLAVVV--------------------GTEPSAPP 368
PS +L V G +P+ P
Sbjct: 3638 HKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGSLAPGELARGTENGMKPATPK 3697
Query: 369 APPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFP--EAEAAHTPCSALEPAAALEPQ---- 422
A P P+ + SP+ G GGG P ++E A TP P+ + P+
Sbjct: 3698 AKPGPS---SQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPA 3754
Query: 423 -----AAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPP----------IPSPPP 467
+ +GP G + + S + KG P PS P
Sbjct: 3755 RAQAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPD 3814
Query: 468 SPPPSPAPLEPSSRV 482
PP +P SRV
Sbjct: 3815 KPPRTPRKQATPSRV 3829
Score = 36.2 bits (82), Expect = 0.19
Identities = 74/305 (24%), Positives = 96/305 (31%), Gaps = 50/305 (16%)
Query: 286 AHTSPSSSSSSSSSGFAEPLEIRPSPPTSRGGSSRGGTAIL---LLTGLEQRAGGL---- 338
AH++P S S + L RP GS+RG + L G RA G+
Sbjct: 361 AHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSP 420
Query: 339 --TPTRHLAPQADPRPSMSLAVVVGTEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGV 396
T AP P L PP P A F P GQ Q
Sbjct: 421 GPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSA 480
Query: 397 SPDFPEAEAAHTPC-SALE-------PAAALEPQAAARG---------------PPPQSV 433
+P+ P +E PA E Q ++G P +S
Sbjct: 481 PLPWPQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSS 540
Query: 434 AGGRRGNCFFIQDDDSGEELKGHGAAPPIPSP---PPSPPP---------SPAPLEPSSR 481
GG + D G + G A P SP P PPP SP P P++
Sbjct: 541 QGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLP-SPATN 599
Query: 482 VGRGEALFGGPVGASELEPFS-LSSFPDLMGELISDEAPSIP----APTPQLSPALSTIT 536
P+ +S P S S P +G P+ P +P P P S T
Sbjct: 600 TAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPT 659
Query: 537 DFSPE 541
+ PE
Sbjct: 660 HYQPE 664
Score = 35.8 bits (81), Expect = 0.25
Identities = 46/190 (24%), Positives = 65/190 (34%), Gaps = 44/190 (23%)
Query: 346 PQADPRPSMSLAVVVGTEPSAPPAPPSPAFDPDRFLNSPQRGQTYGGGQGVSPDFPEAEA 405
P+ P P+M+ + S+P P P + + +G GGQ + + PEA+
Sbjct: 6 PRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEAQP 65
Query: 406 AHTPCSALEPAAALEPQAAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAPPIPSP 465
L+P + RG P S G+RG+
Sbjct: 66 RQARDGELKP-------PSLRGQAPSSTP-GKRGS------------------------- 92
Query: 466 PPSPPPSPAPLE-PSSRVGRGEALFGGPVGASELEPFSLSSFPDLMGELISDEAPSIPAP 524
P PP +PL+ PS GR E G P L S + P L DE P P
Sbjct: 93 -PQTPPGRSPLQAPSRLAGRAE---GSPPQRYILGIASSRTKPTL------DETPENPQL 142
Query: 525 TPQLSPALST 534
P + T
Sbjct: 143 EAAQLPEVDT 152
Score = 33.5 bits (75), Expect = 1.2
Identities = 57/200 (28%), Positives = 71/200 (35%), Gaps = 14/200 (7%)
Query: 304 PLEIRPSPPTSRGGSSRGGTAILLLTGLEQRAGGLTPTRHLAPQ--ADPRPSMSLAVVVG 361
P + PSP G G L+G G H AP+ +D ++
Sbjct: 327 PTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAA----HSAPRPFSDSLHKSLTKILPE 382
Query: 362 TEPSAPPAPPSPAFDPDRFLNSPQRGQTY-GGGQGVSPDFPEAE-AAHTPCSALEPAAAL 419
PSA S P GQ Y G SP P+ E AA P A P
Sbjct: 383 RPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARLPQL-W 441
Query: 420 EPQAAARGPPPQSVAGGRRGNCFFIQDDDSGEELKGHGAAP-PIPSPPPSPPPSPAPLEP 478
+P AA PP R + FF G+ L +AP P P P+ PSP +E
Sbjct: 442 DPTAAPYPTPPGGPLAATR-SMFFNGQPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEM 500
Query: 479 SSRV---GRGEALFGGPVGA 495
SR+ G GG GA
Sbjct: 501 LSRLPFPAGGPEWQGGSQGA 520
Score = 32.7 bits (73), Expect = 2.1
Identities = 40/169 (23%), Positives = 58/169 (34%), Gaps = 32/169 (18%)
Query: 265 PHAHPPEPPP-LIAPLPPELPKAHTSPSSSSSSSSSGFAEPLEIRPSPPTSRGGSSRGGT 323
PH P PPP ++ P E P SP+++++ S+ P+ P+ P+S
Sbjct: 572 PHGTPSLPPPRVVGASPSESPL--PSPATNTAGSTCSSLSPMSSSPANPSSEE------- 622
Query: 324 AILLLTGLEQRAGGLTPTRHLAPQADPRPSMSLAVVVGTEPSAP-PAPPSPAFDPDRFLN 382
Q G L P+ P P+ E +P P+P P P +
Sbjct: 623 --------SQLPGPLGPSAFFHPPTHPQ-----------ETGSPFPSPEPPHSLPTHYQP 663
Query: 383 SPQRGQTY-GGGQGVSPDFPEAEAAHTPCSALEPAAALEPQAAARGPPP 430
P + + G G F E P E Q R PPP
Sbjct: 664 EPAKAFPFPADGLGAEGAFQCLEETPFPHEGPEVGRG-GLQGFPRAPPP 711
Score = 31.2 bits (69), Expect = 6.2
Identities = 34/123 (27%), Positives = 52/123 (42%), Gaps = 7/123 (5%)
Query: 860 PDGSPPPAPLPASEMTMEDMAPGQLSSGVPEAPLLLMDYEATNSKGPLSSLPALPPASDD 919
P + P PLPAS++ MED A +L S + EA L M+Y++ N + S +
Sbjct: 818 PSLAATPFPLPASDLDMEDDA--KLDSLITEA-LNGMEYQSDNPEIDSSFIDVFADEEPS 874
Query: 920 GAAPEDADSPQAVDVIPVDMISLAKQIIEATPE-RIKREDFVGLPEAGASMRERTGAVGL 978
G + P + ATP+ + R G P G R +T ++GL
Sbjct: 875 GPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARG---RPKTRSLGL 931
Query: 979 SET 981
+ T
Sbjct: 932 APT 934
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,517,667
Number of Sequences: 37866
Number of extensions: 3473744
Number of successful extensions: 47026
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 288
Number of HSP's successfully gapped in prelim test: 1357
Number of HSP's that attempted gapping in prelim test: 26799
Number of HSP's gapped (non-prelim): 14154
length of query: 1202
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1088
effective length of database: 13,930,794
effective search space: 15156703872
effective search space used: 15156703872
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.