BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|29789445 desmoglein 4 isoform 2 [Homo sapiens] (1040 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|29789445 desmoglein 4 isoform 2 [Homo sapiens] 2106 0.0 gi|197313787 desmoglein 4 isoform 1 [Homo sapiens] 2053 0.0 gi|119964718 desmoglein 3 preproprotein [Homo sapiens] 953 0.0 gi|116534898 desmoglein 2 preproprotein [Homo sapiens] 610 e-174 gi|119703744 desmoglein 1 preproprotein [Homo sapiens] 605 e-173 gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo sapi... 365 e-100 gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo sap... 351 2e-96 gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo sapi... 342 8e-94 gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo sapi... 323 7e-88 gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens] 323 7e-88 gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens] 317 5e-86 gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo sap... 310 5e-84 gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens] 303 7e-82 gi|4826669 cadherin 15 preproprotein [Homo sapiens] 301 2e-81 gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens] 295 1e-79 gi|4502719 cadherin 13 preproprotein [Homo sapiens] 278 1e-74 gi|29570800 cadherin-like 26 isoform a [Homo sapiens] 272 1e-72 gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens] 266 1e-70 gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens] 195 2e-49 gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens] 194 3e-49 gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens] 194 3e-49 gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens] 194 4e-49 gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens] 189 9e-48 gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens] 184 5e-46 gi|16753221 cadherin 22 precursor [Homo sapiens] 179 1e-44 gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens] 176 1e-43 gi|221316595 cadherin 17 precursor [Homo sapiens] 176 1e-43 gi|221316593 cadherin 17 precursor [Homo sapiens] 176 1e-43 gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens] 174 3e-43 gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens] 174 5e-43 >gi|29789445 desmoglein 4 isoform 2 [Homo sapiens] Length = 1040 Score = 2106 bits (5456), Expect = 0.0 Identities = 1040/1040 (100%), Positives = 1040/1040 (100%) Query: 1 MDWLFFRNICLLIILMVVMEVNSEFIVEVKEFDIENGTTKWQTVRRQKREWIKFAAACRE 60 MDWLFFRNICLLIILMVVMEVNSEFIVEVKEFDIENGTTKWQTVRRQKREWIKFAAACRE Sbjct: 1 MDWLFFRNICLLIILMVVMEVNSEFIVEVKEFDIENGTTKWQTVRRQKREWIKFAAACRE 60 Query: 61 GEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYGVFTINPRTGEINITSVVDREIT 120 GEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYGVFTINPRTGEINITSVVDREIT Sbjct: 61 GEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYGVFTINPRTGEINITSVVDREIT 120 Query: 121 PLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFSQSVYTASIEENSDANTLVVKLC 180 PLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFSQSVYTASIEENSDANTLVVKLC Sbjct: 121 PLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFSQSVYTASIEENSDANTLVVKLC 180 Query: 181 ATDADEENHLNSKIAYKIVSQEPSGAPMFILNRYTGEVCTMSSFLDREQHSMYNLVVRGS 240 ATDADEENHLNSKIAYKIVSQEPSGAPMFILNRYTGEVCTMSSFLDREQHSMYNLVVRGS Sbjct: 181 ATDADEENHLNSKIAYKIVSQEPSGAPMFILNRYTGEVCTMSSFLDREQHSMYNLVVRGS 240 Query: 241 DRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEENCLSSELIRLQAIDLDEEGT 300 DRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEENCLSSELIRLQAIDLDEEGT Sbjct: 241 DRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEENCLSSELIRLQAIDLDEEGT 300 Query: 301 DNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYEQAPNIQLSIGVKNQADFHYS 360 DNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYEQAPNIQLSIGVKNQADFHYS Sbjct: 301 DNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYEQAPNIQLSIGVKNQADFHYS 360 Query: 361 VASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGIKGSSLLNYVLGTYTAIDLDTGN 420 VASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGIKGSSLLNYVLGTYTAIDLDTGN Sbjct: 361 VASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGIKGSSLLNYVLGTYTAIDLDTGN 420 Query: 421 PATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKSKYIINGIYTAEILAIDDGSGKTAT 480 PATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKSKYIINGIYTAEILAIDDGSGKTAT Sbjct: 421 PATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKSKYIINGIYTAEILAIDDGSGKTAT 480 Query: 481 GTICIEVPDINDYCPNIFPERRTICIDSPSVLISVNEHSYGSPFTFCVVDEPPGIADMWD 540 GTICIEVPDINDYCPNIFPERRTICIDSPSVLISVNEHSYGSPFTFCVVDEPPGIADMWD Sbjct: 481 GTICIEVPDINDYCPNIFPERRTICIDSPSVLISVNEHSYGSPFTFCVVDEPPGIADMWD 540 Query: 541 VRSTNATSAILTAKQVLSPGFYEIPILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGA 600 VRSTNATSAILTAKQVLSPGFYEIPILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGA Sbjct: 541 VRSTNATSAILTAKQVLSPGFYEIPILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGA 600 Query: 601 AGIYTEDITGDTYGPVTEDQAGVSNVGLGPAGIGMMVLGILLLILAPLLLLLCCCKQRQP 660 AGIYTEDITGDTYGPVTEDQAGVSNVGLGPAGIGMMVLGILLLILAPLLLLLCCCKQRQP Sbjct: 601 AGIYTEDITGDTYGPVTEDQAGVSNVGLGPAGIGMMVLGILLLILAPLLLLLCCCKQRQP 660 Query: 661 EGLGTRFAPVPEGGEGVMQSWRIEGAHPEDRDVSNICAPMTASNTQDRMDSSEIYTNTYA 720 EGLGTRFAPVPEGGEGVMQSWRIEGAHPEDRDVSNICAPMTASNTQDRMDSSEIYTNTYA Sbjct: 661 EGLGTRFAPVPEGGEGVMQSWRIEGAHPEDRDVSNICAPMTASNTQDRMDSSEIYTNTYA 720 Query: 721 AGGTVEGGVSGVELNTGMGTAVGLMAAGAAGASGAARKRSSTMGTLRDYADADINMAFLD 780 AGGTVEGGVSGVELNTGMGTAVGLMAAGAAGASGAARKRSSTMGTLRDYADADINMAFLD Sbjct: 721 AGGTVEGGVSGVELNTGMGTAVGLMAAGAAGASGAARKRSSTMGTLRDYADADINMAFLD 780 Query: 781 SYFSEKAYAYADEDEGRPANDCLLIYDHEGVGSPVGSIGCCSWIVDDLDESCMETLDPKF 840 SYFSEKAYAYADEDEGRPANDCLLIYDHEGVGSPVGSIGCCSWIVDDLDESCMETLDPKF Sbjct: 781 SYFSEKAYAYADEDEGRPANDCLLIYDHEGVGSPVGSIGCCSWIVDDLDESCMETLDPKF 840 Query: 841 RTLAEICLNTEIEPFPSHQACIPISTDLPLLGPNYFVNESSGLTPSEVEFQEEMAASEPV 900 RTLAEICLNTEIEPFPSHQACIPISTDLPLLGPNYFVNESSGLTPSEVEFQEEMAASEPV Sbjct: 841 RTLAEICLNTEIEPFPSHQACIPISTDLPLLGPNYFVNESSGLTPSEVEFQEEMAASEPV 900 Query: 901 VHGDIIVTETYGNADPCVQPTTIIFDPQLAPNVVVTEAVMAPVYDIQGNICVPAELADYN 960 VHGDIIVTETYGNADPCVQPTTIIFDPQLAPNVVVTEAVMAPVYDIQGNICVPAELADYN Sbjct: 901 VHGDIIVTETYGNADPCVQPTTIIFDPQLAPNVVVTEAVMAPVYDIQGNICVPAELADYN 960 Query: 961 NVIYAERVLASPGVPDMSNSSTTEGCMGPVMSGNILVGPEIQVMQMMSPDLPIGQTVGST 1020 NVIYAERVLASPGVPDMSNSSTTEGCMGPVMSGNILVGPEIQVMQMMSPDLPIGQTVGST Sbjct: 961 NVIYAERVLASPGVPDMSNSSTTEGCMGPVMSGNILVGPEIQVMQMMSPDLPIGQTVGST 1020 Query: 1021 SPMTSRHRVTRYSNIHYTQQ 1040 SPMTSRHRVTRYSNIHYTQQ Sbjct: 1021 SPMTSRHRVTRYSNIHYTQQ 1040 >gi|197313787 desmoglein 4 isoform 1 [Homo sapiens] Length = 1059 Score = 2053 bits (5319), Expect = 0.0 Identities = 1023/1059 (96%), Positives = 1024/1059 (96%), Gaps = 19/1059 (1%) Query: 1 MDWLFFRNICLLIILMVVMEVNSEFIVEVKEFDIENGTTKWQTVRRQKREWIKFAAACRE 60 MDWLFFRNICLLIILMVVMEVNSEFIVEVKEFDIENGTTKWQTVRRQKREWIKFAAACRE Sbjct: 1 MDWLFFRNICLLIILMVVMEVNSEFIVEVKEFDIENGTTKWQTVRRQKREWIKFAAACRE 60 Query: 61 GEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYGVFTINPRTGEINITSVVDREIT 120 GEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYGVFTINPRTGEINITSVVDREIT Sbjct: 61 GEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYGVFTINPRTGEINITSVVDREIT 120 Query: 121 PLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFSQSVYTASIEENSDANTLVVKLC 180 PLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFSQSVYTASIEENSDANTLVVKLC Sbjct: 121 PLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFSQSVYTASIEENSDANTLVVKLC 180 Query: 181 ATDADEENHLNSKIAYKIVSQEPSGAPMFILNRYTGEVCTMSSFLDREQHSMYNLVVRGS 240 ATDADEENHLNSKIAYKIVSQEPSGAPMFILNRYTGEVCTMSSFLDREQHSMYNLVVRGS Sbjct: 181 ATDADEENHLNSKIAYKIVSQEPSGAPMFILNRYTGEVCTMSSFLDREQHSMYNLVVRGS 240 Query: 241 DRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEENCLSSELIRLQAIDLDEEGT 300 DRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEENCLSSELIRLQAIDLDEEGT Sbjct: 241 DRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEENCLSSELIRLQAIDLDEEGT 300 Query: 301 DNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYEQAPNIQLSIGVKNQADFHYS 360 DNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYEQAPNIQLSIGVKNQADFHYS Sbjct: 301 DNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYEQAPNIQLSIGVKNQADFHYS 360 Query: 361 VASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGIKGSSLLNYVLGTYTAIDLDTGN 420 VASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGIKGSSLLNYVLGTYTAIDLDTGN Sbjct: 361 VASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGIKGSSLLNYVLGTYTAIDLDTGN 420 Query: 421 PATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKSKYIINGIYTAEILAIDDGSGKTAT 480 PATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKSKYIINGIYTAEILAIDDGSGKTAT Sbjct: 421 PATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKSKYIINGIYTAEILAIDDGSGKTAT 480 Query: 481 GTICIEVPDINDYCPNIFPERRTICIDSPSVLISVNEHSYGSPFTFCVVDEPPGIADMWD 540 GTICIEVPDINDYCPNIFPERRTICIDSPSVLISVNEHSYGSPFTFCVVDEPPGIADMWD Sbjct: 481 GTICIEVPDINDYCPNIFPERRTICIDSPSVLISVNEHSYGSPFTFCVVDEPPGIADMWD 540 Query: 541 VRSTNATSAILTAKQVLSPGFYEIPILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGA 600 VRSTNATSAILTAKQVLSPGFYEIPILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGA Sbjct: 541 VRSTNATSAILTAKQVLSPGFYEIPILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGA 600 Query: 601 AGIYTEDITGDTYGPVTEDQAGVSNVGLGPAGIGMMVLGILLLILAPLLLLLCCCKQRQP 660 AGIYTEDITGDTYGPVTEDQAGVSNVGLGPAGIGMMVLGILLLILAPLLLLLCCCKQRQP Sbjct: 601 AGIYTEDITGDTYGPVTEDQAGVSNVGLGPAGIGMMVLGILLLILAPLLLLLCCCKQRQP 660 Query: 661 EGLGTRFAPVPEGGEGVMQSWRIEGAHPEDRDVSNICAP-------------------MT 701 EGLGTRFAPVPEGGEGVMQSWRIEGAHPEDR S P T Sbjct: 661 EGLGTRFAPVPEGGEGVMQSWRIEGAHPEDRLFSAYALPGGGGTADGGGSVLGRCALQAT 720 Query: 702 ASNTQDRMDSSEIYTNTYAAGGTVEGGVSGVELNTGMGTAVGLMAAGAAGASGAARKRSS 761 + SEIYTNTYAAGGTVEGGVSGVELNTGMGTAVGLMAAGAAGASGAARKRSS Sbjct: 721 PALLNQHPPFSEIYTNTYAAGGTVEGGVSGVELNTGMGTAVGLMAAGAAGASGAARKRSS 780 Query: 762 TMGTLRDYADADINMAFLDSYFSEKAYAYADEDEGRPANDCLLIYDHEGVGSPVGSIGCC 821 TMGTLRDYADADINMAFLDSYFSEKAYAYADEDEGRPANDCLLIYDHEGVGSPVGSIGCC Sbjct: 781 TMGTLRDYADADINMAFLDSYFSEKAYAYADEDEGRPANDCLLIYDHEGVGSPVGSIGCC 840 Query: 822 SWIVDDLDESCMETLDPKFRTLAEICLNTEIEPFPSHQACIPISTDLPLLGPNYFVNESS 881 SWIVDDLDESCMETLDPKFRTLAEICLNTEIEPFPSHQACIPISTDLPLLGPNYFVNESS Sbjct: 841 SWIVDDLDESCMETLDPKFRTLAEICLNTEIEPFPSHQACIPISTDLPLLGPNYFVNESS 900 Query: 882 GLTPSEVEFQEEMAASEPVVHGDIIVTETYGNADPCVQPTTIIFDPQLAPNVVVTEAVMA 941 GLTPSEVEFQEEMAASEPVVHGDIIVTETYGNADPCVQPTTIIFDPQLAPNVVVTEAVMA Sbjct: 901 GLTPSEVEFQEEMAASEPVVHGDIIVTETYGNADPCVQPTTIIFDPQLAPNVVVTEAVMA 960 Query: 942 PVYDIQGNICVPAELADYNNVIYAERVLASPGVPDMSNSSTTEGCMGPVMSGNILVGPEI 1001 PVYDIQGNICVPAELADYNNVIYAERVLASPGVPDMSNSSTTEGCMGPVMSGNILVGPEI Sbjct: 961 PVYDIQGNICVPAELADYNNVIYAERVLASPGVPDMSNSSTTEGCMGPVMSGNILVGPEI 1020 Query: 1002 QVMQMMSPDLPIGQTVGSTSPMTSRHRVTRYSNIHYTQQ 1040 QVMQMMSPDLPIGQTVGSTSPMTSRHRVTRYSNIHYTQQ Sbjct: 1021 QVMQMMSPDLPIGQTVGSTSPMTSRHRVTRYSNIHYTQQ 1059 >gi|119964718 desmoglein 3 preproprotein [Homo sapiens] Length = 999 Score = 953 bits (2464), Expect = 0.0 Identities = 504/1005 (50%), Positives = 674/1005 (67%), Gaps = 58/1005 (5%) Query: 4 LFFRNICLLIILMVVMEVNSEFIVEVKEFDIENGTTKWQTVRRQKREWIKFAAACREGED 63 LF R L I +VV+ V+ E +E K E T Q RRQKREW+KFA CREGED Sbjct: 4 LFPRTTGALAIFVVVILVHGELRIETKGQYDEEEMTMQQAKRRQKREWVKFAKPCREGED 63 Query: 64 NSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYGVFTINPRTGEINITSVVDREITPLF 123 NSKRNPIAKI SD ++ QKITYRISGVGID+PP+G+F ++ TG+INIT++VDRE TP F Sbjct: 64 NSKRNPIAKITSDYQATQKITYRISGVGIDQPPFGIFVVDKNTGDINITAIVDREETPSF 123 Query: 124 LIYCRALNSRGEDLERPLELRVKVMDINDNAPVFSQSVYTASIEENSDANTLVVKLCATD 183 LI CRALN++G D+E+PL L VK++DINDN PVFSQ ++ IEENS +N+LV+ L ATD Sbjct: 124 LITCRALNAQGLDVEKPLILTVKILDINDNPPVFSQQIFMGEIEENSASNSLVMILNATD 183 Query: 184 ADEENHLNSKIAYKIVSQEPSGAPMFILNRYTGEVCTMSSFLDREQHSMYNLVVRGSDRD 243 ADE NHLNSKIA+KIVSQEP+G PMF+L+R TGEV T+++ LDREQ S Y LVV G+D+D Sbjct: 184 ADEPNHLNSKIAFKIVSQEPAGTPMFLLSRNTGEVRTLTNSLDREQASSYRLVVSGADKD 243 Query: 244 GAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEENCLSSELIRLQAIDLDEEGTDNW 303 G +GLS++C+C IKV DVNDNFP + YSA IEEN LSSEL+R Q DLDEE TDNW Sbjct: 244 G--EGLSTQCECNIKVKDVNDNFPMFRDSQYSARIEENILSSELLRFQVTDLDEEYTDNW 301 Query: 304 LAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYEQAPNIQLSIGVKNQADFHYSVAS 363 LA Y SGN+GNWF+IQTDP+TNEGILKVVK LDYEQ +++LSI VKN+A+FH SV S Sbjct: 302 LAVYFFTSGNEGNWFEIQTDPRTNEGILKVVKALDYEQLQSVKLSIAVKNKAEFHQSVIS 361 Query: 364 QFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGIKGSSLLNYVLGTYTAIDLDTGNPAT 423 ++++ TPV IQV++VREG AF P++ F+V++GI L++Y+LGTY AID DT A+ Sbjct: 362 RYRVQSTPVTIQVINVREGIAFRPASKTFTVQKGISSKKLVDYILGTYQAIDEDTNKAAS 421 Query: 424 DVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKSKYIINGIYTAEILAIDDGSGKTATGTI 483 +V+Y++G + G +L IDS+T EI+F + ++ S +I+N TAE+LAID+ +GKT+TGT+ Sbjct: 422 NVKYVMGRNDGGYLMIDSKTAEIKFVKNMNRDSTFIVNKTITAEVLAIDEYTGKTSTGTV 481 Query: 484 CIEVPDINDYCPNIFPERRTICIDSPSVLISVN--EHSYGSPFTFCVVDEPPGIADMWDV 541 + VPD ND CP E+ +C SPSV++S + Y P+TF + D+P + +W + Sbjct: 482 YVRVPDFNDNCPTAVLEKDAVCSSSPSVVVSARTLNNRYTGPYTFALEDQPVKLPAVWSI 541 Query: 542 RSTNATSAILTAKQVLSPGFYEIPILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGAA 601 + NATSA+L A++ + PG Y I +++ DS N CE+ + + L C CD+ +C S Sbjct: 542 TTLNATSALLRAQEQIPPGVYHISLVLTDSQNNRCEMPRSLTLEVCQCDNRGICGTS--- 598 Query: 602 GIYTEDITGDTYGPVTEDQAGVSNVGLGPAGIGMMVLGILLLILAPLLLLLCCCKQRQPE 661 Y G YG + LGPA IG+++LG+LLL+LAPLLLL C C Sbjct: 599 --YPTTSPGTRYGRPHSGR-------LGPAAIGLLLLGLLLLLLAPLLLLTCDCGAGSTG 649 Query: 662 GLGTRFAPVPEGGEGVMQSWRIEGAHPEDRDVSNICAPMTASNTQDRMDSSEIYTNTYAA 721 G+ F PVP+G EG + W IEGAHPED++++NIC P +N D M+SSE+ TNTYA Sbjct: 650 GVTGGFIPVPDGSEGTIHQWGIEGAHPEDKEITNICVPPVTANGADFMESSEVCTNTYAR 709 Query: 722 GGTVEGGVSGVELNTGMGTA-------------VGLMAAG----------AAGASGAARK 758 G VE G SG+E+ T +G A V A+G ++G SG R Sbjct: 710 GTAVE-GTSGMEMTTKLGAATESGGAAGFATGTVSGAASGFGAATGVGICSSGQSGTMRT 768 Query: 759 RSSTMGTLRDYADADINMAFLDSYFSEKAYAYADEDEGRPANDCLLIYDHEG---VGSPV 815 R ST GT +DYAD I+M FLDSYFS+KA+A A+ED+G+ ANDCLLIYD+EG GSPV Sbjct: 769 RHSTGGTNKDYADGAISMNFLDSYFSQKAFACAEEDDGQEANDCLLIYDNEGADATGSPV 828 Query: 816 GSIGCCSWIVDDLDESCMETLDPKFRTLAEICLNT-----EIEPFPSHQACIPI-STDLP 869 GS+GCCS+I DDLD+S +++L PKF+ LAEI L E++P PS + I S P Sbjct: 829 GSVGCCSFIADDLDDSFLDSLGPKFKKLAEISLGVDGEGKEVQP-PSKDSGYGIESCGHP 887 Query: 870 L-LGPNYFV-------NESSGLTPSEVEFQEEMAASEPVVHGDIIVTETYGNADPCVQPT 921 + + FV ++ + + Q ++ +P+ HG+ +VTETY + VQP+ Sbjct: 888 IEVQQTGFVKCQTLSGSQGASALSTSGSVQPAVSIPDPLQHGNYLVTETYSASGSLVQPS 947 Query: 922 TIIFDPQLAPNVVVTEAVMAPVYDIQGNICVPAELADYNNVIYAE 966 T FDP L NV+VTE V+ P+ + GN+ P +L + ++ E Sbjct: 948 TAGFDPLLTQNVIVTERVICPISSVPGNLAGPTQLRGSHTMLCTE 992 >gi|116534898 desmoglein 2 preproprotein [Homo sapiens] Length = 1118 Score = 610 bits (1572), Expect = e-174 Identities = 388/1023 (37%), Positives = 558/1023 (54%), Gaps = 98/1023 (9%) Query: 12 LIILMVVMEVNSEFIVEVKEFDIENGTT-KWQTVRRQKREWIKFAAACREGEDNSKRNPI 70 L++L++ V S ++V EN K + RQKR WI A REGED SK+NPI Sbjct: 11 LLLLLICFNVGSGLHLQVLSTRNENKLLPKHPHLVRQKRAWITAPVALREGEDLSKKNPI 70 Query: 71 AKIRSDC--ESNQKITYRISGVGIDRPPYGVFTINPRTGEINITSVVDREITPLFLIYCR 128 AKI SD E KITY+ +G GI PP+G+F N TGE+N+TS++DRE TP FL+ Sbjct: 71 AKIHSDLAEERGLKITYKYTGKGITEPPFGIFVFNKDTGELNVTSILDREETPFFLLTGY 130 Query: 129 ALNSRGEDLERPLELRVKVMDINDNAPVFSQSVYTASIEENSDANTLVVKLCATDADEEN 188 AL++RG ++E+PLELR+KV+DINDN PVF+Q V+ S+EE S A+TLV+K+ ATDADE N Sbjct: 131 ALDARGNNVEKPLELRIKVLDINDNEPVFTQDVFVGSVEELSAAHTLVMKINATDADEPN 190 Query: 189 HLNSKIAYKIVSQEPSGAPMFILNRYTGEVCTMSSFLDREQHSMYNLVVRGSDRDG-AAD 247 LNSKI+Y+IVS EP+ P+F LN+ TGE+ T S LDRE+HS Y L V D +G D Sbjct: 191 TLNSKISYRIVSLEPAYPPVFYLNKDTGEIYTTSVTLDREEHSSYTLTVEARDGNGEVTD 250 Query: 248 GLSSECDCRIKVLDVNDNFPTLEKTSYSASIEENCLSSELIRLQAIDLDEEGTDNWLAQY 307 + +I++LDVNDN P +E +EEN ++ E+ R++ D DE G+DNWLA + Sbjct: 251 KPVKQAQVQIRILDVNDNIPVVENKVLEGMVEENQVNVEVTRIKVFDADEIGSDNWLANF 310 Query: 308 LILSGNDGNWFDIQTDPQTNEGILKVVKMLDYEQAPNIQLSIGVKNQADFHYSVASQFQM 367 SGN+G +F I+TD QTNEGI+ ++K +DYE+ N+ S+ V N+A FH S+ S+++ Sbjct: 311 TFASGNEGGYFHIETDAQTNEGIVTLIKEVDYEEMKNLDFSVIVANKAAFHKSIRSKYKP 370 Query: 368 HPTPVRIQVVDVREGPAFHPSTMAFSVREGIKGSSLLNYVLGTYTAIDLDTGNPATDVRY 427 P P++++V +V+EG F S ++ V E + SS ++G + A D DTG PA RY Sbjct: 371 TPIPIKVKVKNVKEGIHFKSSVISIYVSESMDRSS-KGQIIGNFQAFDEDTGLPA-HARY 428 Query: 428 IIGHDAGSWLKIDSRTGEIQFSREFDKKSKYIINGIYTAEILAI-DDGSGKTATGTICIE 486 + D +W+ +DS T EI+ ++ D +S+Y+ NG YT +I+AI +D KT TGT+ I Sbjct: 429 VKLEDRDNWISVDSVTSEIKLAKLPDFESRYVQNGTYTVKIVAISEDYPRKTITGTVLIN 488 Query: 487 VPDINDYCPNIFPERRTICIDSPSVLISVNE---HSYGSPFTFCVVDEPPGIADMWDVRS 543 V DIND CP + +TIC D+ V ++ + H PF+F V+D+PPG+A+ W + Sbjct: 489 VEDINDNCPTLIEPVQTICHDAEYVNVTAEDLDGHPNSGPFSFSVIDKPPGMAEKWKIAR 548 Query: 544 TNATSAILTAKQVLSPGFYEIPILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGAAGI 603 +TS +L + G EI L+ D+ +C Q++ L C+C C Sbjct: 549 QESTSVLLQQSE-KKLGRSEIQFLISDNQGFSCPEKQVLTLTVCECLHGSGC-------- 599 Query: 604 YTEDITGDTYGPVTEDQAGVSNVGLGPAGIGMMVLGILLLILAPLLLLLCCCKQRQPEGL 663 + D+Y VGLGPA I +M+L LLL+L PLLLL+C C G Sbjct: 600 --REAQHDSY------------VGLGPAAIALMILAFLLLLLVPLLLLMCHC------GK 639 Query: 664 GTR-FAPVPEGGEGVMQSWRIEGAHPEDRDVSNICAPMTASNTQDRMD----SSEIYTNT 718 G + F P+P G ++ W EGA PED+ V + + R + E Sbjct: 640 GAKGFTPIP-GTIEMLHPWNNEGAPPEDKVVPSFLPVDQGGSLVGRNGVGGMAKEATMKG 698 Query: 719 YAAGGTVEGGVSGVELNTGMGTAVGLMAAGA---AGASGA-----ARKRSSTMGTLRDYA 770 ++ V+G E++ L++ A GA+GA K + G RD A Sbjct: 699 SSSASIVKGQHEMSEMDGRWEEHRSLLSGRATQFTGATGAIMTTETTKTARATGASRDMA 758 Query: 771 DAD-----INMAFLDSYFSEKAYAYADEDEGRPANDCLLIYDHEGVGSPVGSIGCCSWIV 825 A +N FL +YF++KA +Y +EDE A DCLL+Y E S SIGCCS+I Sbjct: 759 GAQAAAVALNEEFLRNYFTDKAASYTEEDENHTAKDCLLVYSQEETESLNASIGCCSFIE 818 Query: 826 DDLDESCMETLDPKFRTLAEICL------NTEIEP-----------FPSHQAC---IPIS 865 +LD+ ++ L KF+TLAE+CL N EIE SH C + S Sbjct: 819 GELDDRFLDDLGLKFKTLAEVCLGQKIDINKEIEQRQKPATETSMNTASHSLCEQTMVNS 878 Query: 866 TDLPLLGPNYFVNESSGLTPSEVEFQE---EMAAS------------EPVVHGDIIVTET 910 + G ++ V +S +E QE E + S +P+ ++I TET Sbjct: 879 ENTYSSGSSFPVPKSLQEANAEKVTQEIVTERSVSSRQAQKVATPLPDPMASRNVIATET 938 Query: 911 YGNADPCVQPTTIIFDPQLAPNVVVTEAVMAPVYDIQGNICVPAELADYNNVIYAERVLA 970 + PTT+I P +++VTE V AP + V A+ V+ ERV+ Sbjct: 939 SYVTGSTMPPTTVILGPSQPQSLIVTERVYAP-----ASTLVDQPYANEGTVVVTERVIQ 993 Query: 971 SPG 973 G Sbjct: 994 PHG 996 Score = 33.9 bits (76), Expect = 0.82 Identities = 31/122 (25%), Positives = 52/122 (42%), Gaps = 35/122 (28%) Query: 918 VQPTTIIFDPQLAPNVVVTEAVMAPVYDIQGNICVPAELADYNNVIYAERVLASPGVPDM 977 VQPT + + + NV VTE V+AP +Q + +P E N++ ++ GVP Sbjct: 1029 VQPTLAMPNIAVGQNVTVTERVLAPASTLQSSYQIPTE----NSMTARNTTVSGAGVP-- 1082 Query: 978 SNSSTTEGCMGPVMSGNILVGPEIQVMQMMSPDLPIGQTVGSTSPM-TSRHRVTRYSNIH 1036 GP+ PD + ++ S S + TS RVT++S + Sbjct: 1083 ----------GPL------------------PDFGLEESGHSNSTITTSSTRVTKHSTVQ 1114 Query: 1037 YT 1038 ++ Sbjct: 1115 HS 1116 >gi|119703744 desmoglein 1 preproprotein [Homo sapiens] Length = 1049 Score = 605 bits (1560), Expect = e-173 Identities = 291/503 (57%), Positives = 385/503 (76%), Gaps = 5/503 (0%) Query: 1 MDWLFFRNICLLIILMVVMEVNSEFIVEVKEFDIENGTTKWQTVRRQKREWIKFAAACRE 60 MDW FFR + +L I +VV+EVNSEF ++V++++ +NGT KW ++RRQKREWIKFAAACRE Sbjct: 1 MDWSFFRVVAMLFIFLVVVEVNSEFRIQVRDYNTKNGTIKWHSIRRQKREWIKFAAACRE 60 Query: 61 GEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYGVFTINPRTGEINITSVVDREIT 120 GEDNSKRNPIAKI SDC +NQ++TYRISGVGID+PPYG+F IN +TGEINITS+VDRE+T Sbjct: 61 GEDNSKRNPIAKIHSDCAANQQVTYRISGVGIDQPPYGIFVINQKTGEINITSIVDREVT 120 Query: 121 PLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFSQSVYTASIEENSDANTLVVKLC 180 P F+IYCRALNS G+DLERPLELRV+V+DINDN PVFS + + IEENS+ANTLV+ L Sbjct: 121 PFFIIYCRALNSMGQDLERPLELRVRVLDINDNPPVFSMATFAGQIEENSNANTLVMILN 180 Query: 181 ATDADEENHLNSKIAYKIVSQEPSGAPMFILNRYTGEVCTMSSFLDREQHSMYNLVVRGS 240 ATDADE N+LNSKIA+KI+ QEPS +PMFI+NR TGE+ TM++FLDREQ+ Y L VRGS Sbjct: 181 ATDADEPNNLNSKIAFKIIRQEPSDSPMFIINRNTGEIRTMNNFLDREQYGQYALAVRGS 240 Query: 241 DRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEENCLSSELIRLQAIDLDEEGT 300 DRDG ADG+S+EC+C IK+LDVNDN P +E++SY+ I+EN L+S L+ ++ IDLDEE + Sbjct: 241 DRDGGADGMSAECECNIKILDVNDNIPYMEQSSYTIEIQENTLNSNLLEIRVIDLDEEFS 300 Query: 301 DNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYEQAPNIQLSIGVKNQADFHYS 360 NW+A +SGN+GNWF+I+ + +TN GILKVVK LDYE ++QLSIGV+N+A+FH+S Sbjct: 301 ANWMAVIFFISGNEGNWFEIEMNERTNVGILKVVKPLDYEAMQSLQLSIGVRNKAEFHHS 360 Query: 361 VASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGIKGSSLLNYVLGTYTAIDLDTGN 420 + SQ+++ + + + V++V EGP F P + + V G GS N +G + A DLDTG Sbjct: 361 IMSQYKLKASAISVTVLNVIEGPVFRPGSKTYVV-TGNMGS---NDKVGDFVATDLDTGR 416 Query: 421 PATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKSKYIINGIYTAEILAIDDGSGKTAT 480 P+T VRY++G++ L +DSRTG++ + K+ ++ G Y IL+IDD +T T Sbjct: 417 PSTTVRYVMGNNPADLLAVDSRTGKLTLKNKVTKEQYNMLGGKYQGTILSIDDNLQRTCT 476 Query: 481 GTICIEVPDI-NDYCPNIFPERR 502 GTI I + ND N P + Sbjct: 477 GTININIQSFGNDDRTNTEPNTK 499 Score = 278 bits (712), Expect = 1e-74 Identities = 280/1006 (27%), Positives = 445/1006 (44%), Gaps = 193/1006 (19%) Query: 191 NSKIAYKI----VSQEPSGAPMFILNRYTGEVCTMSSFLDREQHSMYNLVVRGSDRDGAA 246 N ++ Y+I + Q P G +F++N+ TGE+ ++S +DRE + + R + G Sbjct: 80 NQQVTYRISGVGIDQPPYG--IFVINQKTGEI-NITSIVDREVTPFFIIYCRALNSMG-- 134 Query: 247 DGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEENCLSSELIR-LQAIDLDEEGTDNWLA 305 L + R++VLD+NDN P +++ IEEN ++ L+ L A D DE N Sbjct: 135 QDLERPLELRVRVLDINDNPPVFSMATFAGQIEENSNANTLVMILNATDADEPNNLNSKI 194 Query: 306 QYLIL--SGNDGNWFDIQTDPQTNEGILKVVK-MLDYEQAPNIQLSIGVKNQADFHYSVA 362 + I+ +D F I N G ++ + LD EQ L++ ++ ++ Sbjct: 195 AFKIIRQEPSDSPMFIINR----NTGEIRTMNNFLDREQYGQYALAVRGSDRDGGADGMS 250 Query: 363 SQFQMHPTPVRIQVVDVREG-PAFHPSTMAFSVREGIKGSSLLNYVLGTYTAIDLDTGNP 421 ++ + + I+++DV + P S+ ++E S+LL IDLD Sbjct: 251 AECECN-----IKILDVNDNIPYMEQSSYTIEIQENTLNSNLLEI-----RVIDLDEEFS 300 Query: 422 AT--DVRYIIGHDAGSW--LKIDSRT--GEIQFSREFDKKSKYIIN---GIYT-AEILAI 471 A V + I + G+W ++++ RT G ++ + D ++ + G+ AE Sbjct: 301 ANWMAVIFFISGNEGNWFEIEMNERTNVGILKVVKPLDYEAMQSLQLSIGVRNKAEFHHS 360 Query: 472 DDGSGKTATGTICIEVPDINDYCPNIFPERRTICI-------DSPSVLISVNEHSYGSPF 524 K I + V ++ + P P +T + D ++ + + G P Sbjct: 361 IMSQYKLKASAISVTVLNVIEG-PVFRPGSKTYVVTGNMGSNDKVGDFVATDLDT-GRPS 418 Query: 525 TFC--VVDEPPGIADMWDVRSTNATSAILTAKQVLSP-------GFYEIPIL-VKDSYNR 574 T V+ P D+ + ++ + LT K ++ G Y+ IL + D+ R Sbjct: 419 TTVRYVMGNNPA-----DLLAVDSRTGKLTLKNKVTKEQYNMLGGKYQGTILSIDDNLQR 473 Query: 575 ACELAQMVQLYACDCDD------------NHMCLDSGAAGIYTEDITGDTYGPVTEDQAG 622 C + + + DD N +S ++ Y T V + G Sbjct: 474 TCTGTININIQSFGNDDRTNTEPNTKITTNTGRQESTSSTNYDTSTTSTDSSQVYSSEPG 533 Query: 623 -------VSNVGLGPAGIGMMVLGILLLILAPLLLLLCCCKQRQPEGLGTRFAPVPEGGE 675 NV GPAGIG++++G L+L L P L++ C C G F PVPE + Sbjct: 534 NGAKDLLSDNVHFGPAGIGLLIMGFLVLGLVPFLMICCDCGGAPRSAAG--FEPVPECSD 591 Query: 676 GVMQSWRIEGAHPEDRDVSNICA--PMTASNTQDRMDSSEIYTNTYAAGGTVEGGVSGVE 733 G + SW +EG PE RD++ + P +N + +D+S +YTN Y GG + G E Sbjct: 592 GAIHSWAVEGPQPEPRDITTVIPQIPPDNANIIECIDNSGVYTNEY--GGREMQDLGGGE 649 Query: 734 LNTGMGTAVGLMAAGAAGA----SGAARKRSSTMGTLRDYADADINMAFLDSYFSEKAYA 789 TG G+ +G SG R+ S +R+ + +NM F++SYF +KAYA Sbjct: 650 RMTGFELTEGVKTSGMPEICQEYSGTLRRNS-----MRECREGGLNMNFMESYFCQKAYA 704 Query: 790 YADEDEGRPANDCLLIYDHEGVGSPVGSIGCCSWIVDDLDESCMETLDPKFRTLAEICLN 849 YADEDEGRP+NDCLLIYD EGVGSP GS+GCCS+I +DLD+S ++TL PKF+ LA+I L Sbjct: 705 YADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIGEDLDDSFLDTLGPKFKKLADISLG 764 Query: 850 TEIEP-----FP---SHQACIPISTD---------------------------------L 868 E P +P + C+P T+ Sbjct: 765 KESYPDLDPSWPPQSTEPVCLPQETEPVVSGHPPISPHFGTTTVISESTYPSGPGVLHPK 824 Query: 869 PLLGP----NYFVNES----SGLTPSEVEFQEEMAASEPVV-------------HG---- 903 P+L P N V ES L PS V + AS VV HG Sbjct: 825 PILDPLGYGNVTVTESYTTSDTLKPS-VHVHDNRPASNVVVTERVVGPISGADLHGMLEM 883 Query: 904 -------DIIVTETYGNADPCVQPTTIIFDPQLAPNVVVTEAVMAPVYDIQGNICVPAEL 956 ++IVTE + + I P+ + NVVVTE V+ P + G++ + EL Sbjct: 884 PDLRDGSNVIVTERVIAPSSSLPTSLTIHHPRESSNVVVTERVIQPTSGMIGSLSMHPEL 943 Query: 957 ADYNNVIYAERVLASPGVPDMSNSSTTEGCMGP-------------VMSGNILVGPEIQV 1003 A+ +NVI ERV++ GV +S ++ G +G +SG + G I + Sbjct: 944 ANAHNVIVTERVVSGAGVTGISGTTGISGGIGSSGLVGTSMGAGSGALSGAGISGGGIGL 1003 Query: 1004 MQM----------MSPDLPIGQTVGSTSPMTSRHRVTRYSNIHYTQ 1039 + S D QT+GS SP T+R R+T+YS + Y++ Sbjct: 1004 SSLGGTASIGHMRSSSDHHFNQTIGSASPSTARSRITKYSTVQYSK 1049 >gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo sapiens] Length = 901 Score = 365 bits (936), Expect = e-100 Identities = 257/827 (31%), Positives = 388/827 (46%), Gaps = 69/827 (8%) Query: 39 TKWQTVRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYG 98 TK + +RR KR W + E + +++SD N I Y I G G+D+ P Sbjct: 125 TKEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQEPRN 184 Query: 99 VFTINPRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFS 158 +F + TG + T VDRE F I A G E PL L +K+ D NDN P+F+ Sbjct: 185 LFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNYPIFT 244 Query: 159 QSVYTASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEPSGAPMFILNRYTGEV 218 + YT +I EN T V ++CATD DE + +++++ Y I+ Q P +F ++ TG + Sbjct: 245 EETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPTLFSMHPTTGVI 304 Query: 219 CTMSSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASI 278 T SS LDRE Y L ++ D DG GL + C I + DVND+ PT +TSY S+ Sbjct: 305 TTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVTSV 364 Query: 279 EENCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLD 338 EEN + E++R+ D D T NW A Y IL GN+ F I TD +TNEG+L VVK L+ Sbjct: 365 EENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPLN 424 Query: 339 YEQAPNIQLSIGVKNQADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGI 398 YE+ + L IGV N+A F + + M V + V D EGP +P ++E Sbjct: 425 YEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKENA 484 Query: 399 KGSSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKSKY 458 + + N Y A D +T ++ +RY D W+ ID TG I+ R D++++ Sbjct: 485 EVGTTSN----GYKAYDPET-RSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAET 539 Query: 459 IINGIYTAEILAIDDGSGKTATGTICIEVPDINDYCPNIFPERRTICIDSPS------VL 512 I NGIY +LA D G G+T TGT+ I + D+ND P F ++T+ I P+ V Sbjct: 540 IKNGIYNITVLASDQG-GRTCTGTLGIILQDVNDNSP--FIPKKTVIICKPTMSSAEIVA 596 Query: 513 ISVNEHSYGSPFTFCVVDEPPGIADMWDVRSTNATSAILTAKQVLSPGFYEIPILVKDSY 572 + +E +G PF F + + MW +++ N T+A L+ + G Y +PI V+D Sbjct: 597 VDPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRDRL 656 Query: 573 NRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVSNVGLGPAG 632 + + V L CDC + C + + G V LG Sbjct: 657 GMSSVTSLDVTL--CDCITENDCTHR------------------VDPRIGGGGVQLGKWA 696 Query: 633 IGMMVLGILLLILAPLLLLLCCCKQRQPEGLGTRFAPVPEGGEGVMQSWRIEGAHPEDRD 692 I ++LGI LL +L L C G G + ++ P+D Sbjct: 697 ILAILLGIALLFC--ILFTLVC------------------GASGTSKQPKV---IPDDLA 733 Query: 693 VSNICAPMTASNTQDRMDSSEIYTNTYAAGGTVEG--GVSGVELNTGMGTAVGLMAAG-- 748 N+ T + D++ S+ +T T G + +G G G + G + ++ G Sbjct: 734 QQNLIVSNTEAPGDDKVYSANGFT-TQTVGASAQGVCGTVGSGIKNGGQETIEMVKGGHQ 792 Query: 749 ---AAGASGAARKRSSTMGTLRDYADADINM----AFLDSYFSEKAYAYADEDEGRPAND 801 + +G S G + + +F EK Y ++ + A D Sbjct: 793 TSESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEKVYLCNQDENHKHAQD 852 Query: 802 CLLIYDHEGVGSPVGSIGCCSWIVDDLDESCMETLDPKFRTLAEICL 848 +L Y++EG GS GS+GCCS ++ ++ L+PKFRTLAE C+ Sbjct: 853 YVLTYNYEGRGSVAGSVGCCSERQEEDGLEFLDNLEPKFRTLAEACM 899 >gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo sapiens] Length = 896 Score = 351 bits (901), Expect = 2e-96 Identities = 248/825 (30%), Positives = 388/825 (47%), Gaps = 72/825 (8%) Query: 39 TKWQTVRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYG 98 T+ +RR KR W + +E + ++ SD N + Y ISG G+D+ P Sbjct: 125 TRETVLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDKEPLN 184 Query: 99 VFTINPRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFS 158 +F I TG + T VDRE +F + A + G + PL L ++V D NDN PVF+ Sbjct: 185 LFYIERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNHPVFT 244 Query: 159 QSVYTASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEPSGAPMFILNRYTGEV 218 +++Y + E+S T V +CATD DE + +++++ Y I+ Q P +F ++ TG + Sbjct: 245 EAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSPGLFSVHPSTGVI 304 Query: 219 CTMSSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASI 278 T+S +LDRE Y+L+++ D DG GL C I V D NDN PT + +Y A + Sbjct: 305 TTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFV 364 Query: 279 EENCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLD 338 EEN + E++R+ D D T NW + IL GN+ F I TD +TNEG+L VVK L+ Sbjct: 365 EENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLN 424 Query: 339 YEQAPNIQLSIGVKNQADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGI 398 YE+ + L IGV N+A F + ++ V + V D+ EGP P+ ++E + Sbjct: 425 YEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENL 484 Query: 399 KGSSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKSKY 458 S +N Y A D + N +RY HD W+ ID +G I S+ D++ + Sbjct: 485 AVGSKIN----GYKAYDPENRN-GNGLRYKKLHDPKGWITIDEISGSIITSKILDREVET 539 Query: 459 IINGIYTAEILAIDDGSGKTATGTICIEVPDINDYCPNIFPERRTICID----SPSVLIS 514 N +Y +LAID ++ TGT+ + + D+ND P I E IC + + + Sbjct: 540 PKNELYNITVLAIDK-DDRSCTGTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVD 598 Query: 515 VNEHSYGSPFTFCVVDEPPGIADMWDVRSTNATSAILTAKQVLSPGFYEIPILVKDSYNR 574 +E +G+PF F + + P I+ +W + N T+A L+ ++ Y IPI VKD + Sbjct: 599 PDEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAGFQEYTIPITVKDRAGQ 658 Query: 575 ACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVSNVGLGPAGIG 634 A +++++ C+C C + + + V LG I Sbjct: 659 AA--TKLLRVNLCECTHPTQCRATSRS----------------------TGVILGKWAIL 694 Query: 635 MMVLGILLLILAPLLLLLCCCKQRQPEGLGTRFAPVPEGGEGVMQSWRIEGAHPEDRDVS 694 ++LGI LL + LL L+C G G + R PED Sbjct: 695 AILLGIALL-FSVLLTLVC-------------------GVFGATKGKRF----PEDLAQQ 730 Query: 695 NICAPMTASNTQDRMDSSEIY----TNTYAAG-------GTVEGGVSGVE-LNTGMGTAV 742 N+ T + DR+ S+ + TN + G G GG +E + G T Sbjct: 731 NLIISNTEAPGDDRVCSANGFMTQTTNNSSQGFCGTMGSGMKNGGQETIEMMKGGNQTLE 790 Query: 743 GLMAAGAAGASGAARKRSSTMGTLRDYADADINMAFLDSYFSEKAYAYADEDEGRPANDC 802 AG + R + + R Y ++ + +F EK + ++ P+ D Sbjct: 791 SCRGAGHHHTLDSCRGGHTEVDNCR-YTYSEWH-SFTQPRLGEKLHRCNQNEDRMPSQDY 848 Query: 803 LLIYDHEGVGSPVGSIGCCSWIVDDLDESCMETLDPKFRTLAEIC 847 +L Y++EG GSP GS+GCCS ++ + L+PKF TLAE C Sbjct: 849 VLTYNYEGRGSPAGSVGCCSEKQEEDGLDFLNNLEPKFITLAEAC 893 >gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo sapiens] Length = 894 Score = 342 bits (878), Expect = 8e-94 Identities = 259/826 (31%), Positives = 389/826 (47%), Gaps = 73/826 (8%) Query: 39 TKWQTVRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYG 98 TK ++R KR W A+ E + +I+SD N I Y ISG G+D+ P+ Sbjct: 124 TKDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYTIFYSISGPGVDKEPFN 183 Query: 99 VFTINPRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFS 158 +F I TG+I T +DRE F +Y A + G E PL L +K+ D NDNAP F Sbjct: 184 LFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYPLPLIIKIEDDNDNAPYFE 243 Query: 159 QSVYTASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEPSGAPMFILNRYTGEV 218 V ++ EN + T V K+ ATD DE + L++++ YKI+ Q P F ++ TG + Sbjct: 244 HRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHTRLKYKILQQIPDHPKHFSIHPDTGVI 303 Query: 219 CTMSSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASI 278 T + FLDRE+ Y L++ D G GL + I + D NDN P+ +TSY + Sbjct: 304 TTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEV 363 Query: 279 EENCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLD 338 EEN + E++R++ D D T + A Y IL GN+ F I TDP TNEG+L VVK L+ Sbjct: 364 EENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLN 423 Query: 339 YEQAPNIQLSIGVKNQADFHYSVASQF-QMHPTPVRIQVVDVREGPAFHPSTMAFSVREG 397 YE + L +GV N+A F + +SQ M T V ++++D EGP HP ++G Sbjct: 424 YEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDG 483 Query: 398 I-KGSSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKS 456 G LL Y A+D + + +RY D +W +I+ TG+++ + D++S Sbjct: 484 FPAGQELLG-----YKALDPEISS-GEGLRYQKLGDEDNWFEINQHTGDLRTLKVLDRES 537 Query: 457 KYIINGIYTAEILAIDDGSGKTATGTICIEVPDINDYCPNIFPERRTICIDSP--SVLIS 514 K++ N Y ++A+ D G++ TGT+ + + D ND+ P I E TIC ++ +VL Sbjct: 538 KFVKNNQYNISVVAV-DAVGRSCTGTLVVHLDDYNDHAPQIDKE-VTICQNNEDFAVLKP 595 Query: 515 VNEH--SYGSPFTFCVVDEPPGIADMWDVRSTNATSAILTAKQVLSPGFYEIPILVKDSY 572 V+ G PF F + + + W++ + +AIL +Q L +Y +PI +KD + Sbjct: 596 VDPDGPENGPPFQFFLDN---SASKNWNIEEKDGKTAILRQRQNLDYNYYSVPIQIKDRH 652 Query: 573 NRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVSNVGLGPAG 632 M+ + CDC C + T D+ NV LG Sbjct: 653 GLVA--THMLTVRVCDCSTPSECRMKDKS---TRDVR--------------PNVILGRWA 693 Query: 633 IGMMVLGILLLILAPLLLLLCCC-------KQRQPEGLGTRFAPVPEGGEGVMQSWRIEG 685 I MVLG +LL+ +L C C K+ PE + + V EG Sbjct: 694 ILAMVLGSVLLL---CILFTCFCVTAKRTVKKCFPEDIAQQNLIVS----------NTEG 740 Query: 686 AHPEDRDVSNICAPMTASNTQDRMDSSEIYTNTYAAGGTVEGGVSGVELNTGMGTAVG-- 743 E + +NI PM SN D T + GTV G G++ G Sbjct: 741 PGEEVTE-ANIRLPMQTSNICD----------TSMSVGTVGG--QGIKTQQSFEMVKGGY 787 Query: 744 -LMAAGAAGASGAARKRSSTMGTLRDYADADINMAFLDSYFSEKAYAYADEDEGRPANDC 802 L + G + G YA D +F EK Y ++E + D Sbjct: 788 TLDSNKGGGHQTLESVKGVGQGDTGRYAYTDW-QSFTQPRLGEKVYLCGQDEEHKHCEDY 846 Query: 803 LLIYDHEGVGSPVGSIGCCSWIVDDLDESCMETLDPKFRTLAEICL 848 + Y++EG GS GS+GCCS ++ ++ L+PKFRTLA+ C+ Sbjct: 847 VCSYNYEGKGSLAGSVGCCSDRQEEEGLEFLDHLEPKFRTLAKTCI 892 >gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo sapiens] Length = 847 Score = 323 bits (827), Expect = 7e-88 Identities = 226/718 (31%), Positives = 339/718 (47%), Gaps = 60/718 (8%) Query: 39 TKWQTVRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYG 98 TK + +RR KR W + E + +++SD N I Y I G G+D+ P Sbjct: 125 TKEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQEPRN 184 Query: 99 VFTINPRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFS 158 +F + TG + T VDRE F I A G E PL L +K+ D NDN P+F+ Sbjct: 185 LFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNYPIFT 244 Query: 159 QSVYTASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEPSGAPMFILNRYTGEV 218 + YT +I EN T V ++CATD DE + +++++ Y I+ Q P +F ++ TG + Sbjct: 245 EETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPTLFSMHPTTGVI 304 Query: 219 CTMSSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASI 278 T SS LDRE Y L ++ D DG GL + C I + DVND+ PT +TSY S+ Sbjct: 305 TTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVTSV 364 Query: 279 EENCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLD 338 EEN + E++R+ D D T NW A Y IL GN+ F I TD +TNEG+L VVK L+ Sbjct: 365 EENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPLN 424 Query: 339 YEQAPNIQLSIGVKNQADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGI 398 YE+ + L IGV N+A F + + M V + V D EGP +P ++E Sbjct: 425 YEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKENA 484 Query: 399 KGSSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKSKY 458 + + N Y A D +T ++ +RY D W+ ID TG I+ R D++++ Sbjct: 485 EVGTTSN----GYKAYDPET-RSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAET 539 Query: 459 IINGIYTAEILAIDDGSGKTATGTICIEVPDINDYCPNIFPERRTICIDSPS------VL 512 I NGIY +LA D G G+T TGT+ I + D+ND P F ++T+ I P+ V Sbjct: 540 IKNGIYNITVLASDQG-GRTCTGTLGIILQDVNDNSP--FIPKKTVIICKPTMSSAEIVA 596 Query: 513 ISVNEHSYGSPFTFCVVDEPPGIADMWDVRSTNATSAILTAKQVLSPGFYEIPILVKDSY 572 + +E +G PF F + + MW +++ N T+A L+ + G Y +PI V+D Sbjct: 597 VDPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRDRL 656 Query: 573 NRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVSNVGLGPAG 632 + + V L CDC + C + + G V LG Sbjct: 657 GMSSVTSLDVTL--CDCITENDCTHR------------------VDPRIGGGGVQLGKWA 696 Query: 633 IGMMVLGILLLILAPLLLLLCCCKQRQPEGLGTRFAPVPEGGEGVMQSWRIEGAHPEDRD 692 I ++LGI LL +L L C G G + ++ P+D Sbjct: 697 ILAILLGIALLFC--ILFTLVC------------------GASGTSKQPKV---IPDDLA 733 Query: 693 VSNICAPMTASNTQDRMDSSEIYTNTYAAGGTVEG--GVSGVELNTGMGTAVGLMAAG 748 N+ T + D++ S+ +T T G + +G G G + G + ++ G Sbjct: 734 QQNLIVSNTEAPGDDKVYSANGFT-TQTVGASAQGVCGTVGSGIKNGGQETIEMVKGG 790 >gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens] Length = 916 Score = 323 bits (827), Expect = 7e-88 Identities = 239/815 (29%), Positives = 377/815 (46%), Gaps = 81/815 (9%) Query: 44 VRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYGVFTIN 103 +RR+KR+W+ E + +IRSD +++ I Y I+GVG D+PP VF+I+ Sbjct: 164 LRRRKRDWVIPPINVPENSRGPFPQQLVRIRSDKDNDIPIRYSITGVGADQPPMEVFSID 223 Query: 104 PRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFSQSVYT 163 +G + +T +DRE + + A++ G +E P++L + V+D+NDN P F VY Sbjct: 224 SMSGRMYVTRPMDREEHASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFINQVYN 283 Query: 164 ASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEPSGAP--MFILNRYTGEVCTM 221 S++E S T V+ + A DAD+ N + Y+IV+Q P MF +N TG++ T+ Sbjct: 284 GSVDEGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGDIVTV 343 Query: 222 SSFLDREQHSMYNLVVRGSDRDGAAD-GLSSECDCRIKVLDVNDNFPTLEKTSYSASIEE 280 ++ LDRE+ Y ++V+ +D +G + GLS+ I V DVNDN P ++++ + E Sbjct: 344 AAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAGEVPE 403 Query: 281 NCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYE 340 N + + + L +D D+ + NW A Y I+SG+ F ++TDP TNEG++ VVK +DYE Sbjct: 404 NRVETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYE 463 Query: 341 QAPNIQLSIGVKNQADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGIKG 400 L++ V NQA + FQ V I ++D+ E P F + + EG+ Sbjct: 464 LNRAFMLTVMVSNQAPLASGIQMSFQ-STAGVTISIMDINEAPYFPSNHKLIRLEEGVPP 522 Query: 401 SSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKSKYII 460 + VL T++A+D D VRY D SWL I++ G+I + D++S Y Sbjct: 523 GT----VLTTFSAVDPDRFMQQA-VRYSKLSDPASWLHINATNGQITTAAVLDRESLYTK 577 Query: 461 NGIYTAEILAIDDG-SGKTATGTICIEVPDINDYCPNIFPERRTICIDSPSVLISVNEHS 519 N +Y A LA D+G + TGT+ I + DIND P + P+ IC I++ Sbjct: 578 NNVYEATFLAADNGIPPASGTGTLQIYLIDINDNAPELLPKEAQICEKPNLNAINITAAD 637 Query: 520 YG-----SPFTFCVVDEPPGIADMWDVRSTNATSAILTAKQV-LSPGFYEIPILVKDSYN 573 P+ F + P + W + N A L+ + + L G Y++PI+V DS N Sbjct: 638 ADVDPNIGPYVFELPFVPAAVRKNWTITRLNGDYAQLSLRILYLEAGMYDVPIIVTDSGN 697 Query: 574 RACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVSNVGLGPAGI 633 ++++ C CDDN C GA V+ GLG I Sbjct: 698 PPLSNTSIIKVKVCPCDDNGDCTTIGA----------------------VAAAGLGTGAI 735 Query: 634 GMMVLGILLLILAPLLLLLCCCKQRQPEGLGTRFAPVPEGG-EGVMQSWRIEGAHPEDRD 692 + +L +L++L +LL + K+R+ E + PE + + EG ED+D Sbjct: 736 -VAILICILILLTMVLLFVMWMKRREKERHTKQLLIDPEDDVRDNILKYDEEGGGEEDQD 794 Query: 693 VSNICAPMTASNTQDRMDSSEIYTNTYAAGGTVEGGVSGVELNTGMGTAVGLMAAGAAGA 752 D S++ A G V GV V GA Sbjct: 795 ----------------YDLSQL--QQPEAMGHVPSKAPGVR-------RVDERPVGAE-P 828 Query: 753 SGAARKRSSTMGTLRDYADADINMAFLDSYFSEKAYAYADEDEGRPANDCLLIYDHEGVG 812 R G + D+ + + A D D P D LL++D+EG G Sbjct: 829 QYPIRPMVPHPGDIGDFINEGLRAA--------------DNDPTAPPYDSLLVFDYEGSG 874 Query: 813 SPVGSIGCC-SWIVDDLDESCMETLDPKFRTLAEI 846 S GS+ S D D + P+F+ LA++ Sbjct: 875 STAGSVSSLNSSSSGDQDYDYLNDWGPRFKKLADM 909 >gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens] Length = 906 Score = 317 bits (811), Expect = 5e-86 Identities = 242/844 (28%), Positives = 376/844 (44%), Gaps = 103/844 (12%) Query: 24 EFIVEVKEFDIENGTTKWQTVRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQKI 83 E IV ++F +G ++RQKR+W+ E + +IRSD + N + Sbjct: 139 EEIVFPRQFSKHSGH-----LQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDKNLSL 193 Query: 84 TYRISGVGIDRPPYGVFTINPRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLEL 143 Y ++G G D+PP G+F INP +G++++T +DRE F + A++ G +E P+++ Sbjct: 194 RYSVTGPGADQPPTGIFIINPISGQLSVTKPLDREQIARFHLRAHAVDINGNQVENPIDI 253 Query: 144 RVKVMDINDNAPVFSQSVYTASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEP 203 + V+D+NDN P F V+ ++ E S T V+ + A DAD+ N LN + Y+IVSQ P Sbjct: 254 VINVIDMNDNRPEFLHQVWNGTVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRIVSQAP 313 Query: 204 S--GAPMFILNRYTGEVCTMSSFLDREQHSMYNLVVRGSDRDG-AADGLSSECDCRIKVL 260 S MF +N TG++ T+++ LDRE+ Y L+++ +D +G GLS+ I V Sbjct: 314 STPSPNMFTINNETGDIITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVT 373 Query: 261 DVNDNFPTLEKTSYSASIEENCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDI 320 DVNDN P ++ + EN + + L D D+ T W A Y I G+ F I Sbjct: 374 DVNDNPPEFTAMTFYGEVPENRVDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAI 433 Query: 321 QTDPQTNEGILKVVKMLDYEQAPNIQLSIGVKNQADFHYSVASQFQMHPTPVRIQVVDVR 380 QTDP +N+G++ VVK +D+E L++ +NQ + Q T V + V+DV Sbjct: 434 QTDPNSNDGLVTVVKPIDFETNRMFVLTVAAENQVPLAKGIQHPPQSTAT-VSVTVIDVN 492 Query: 381 EGPAFHPSTMAFSVREGIKGSSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKID 440 E P F P+ EG+ ++L T+TA D D ++RY D +WLKID Sbjct: 493 ENPYFAPNPKIIRQEEGLHAGTMLT----TFTAQDPDR-YMQQNIRYTKLSDPANWLKID 547 Query: 441 SRTGEIQFSREFDKKSKYIINGIYTAEILAIDDG-SGKTATGTICIEVPDINDYCPNIFP 499 G+I D++S + N IY A LA D+G + TGT+ I + DIND P + P Sbjct: 548 PVNGQITTIAVLDRESPNVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLP 607 Query: 500 ERRTICIDSPSVLISVNEHSY-----GSPFTFCVVDEPPGIADMWDVRSTNATSAILTAK 554 + C I++ Y PF F + P I W + N A L K Sbjct: 608 QEAETCETPDPNSINITALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNLK 667 Query: 555 -QVLSPGFYEIPILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTY 613 + L G YE+PI++ DS N ++++ C CD N C D + I G Sbjct: 668 IKFLEAGIYEVPIIITDSGNPPKSNISILRVKVCQCDSNGDCTD-------VDRIVG--- 717 Query: 614 GPVTEDQAGVSNVGLGPAGIGMMVLGILLLILAPLLLLLCCCKQRQPEGLGTRFAPVPEG 673 GLG I ++L I++L++ +L+ + K+R E + PE Sbjct: 718 ------------AGLGTGAIIAILLCIIILLIL-VLMFVVWMKRRDKERQAKQLLIDPED 764 Query: 674 G-EGVMQSWRIEGAHPEDR--DVSNICAPMTASNTQ------DRMDSSEIYTNTYAAGGT 724 + + EG ED+ D+S + P T RMD I+ Sbjct: 765 DVRDNILKYDEEGGGEEDQDYDLSQLQQPDTVEPDAIKPVGIRRMDERPIH--------- 815 Query: 725 VEGGVSGVELNTGMGTAVGLMAAGAAGASGAARKRSSTMGTLRDYADADINMAFLDSYFS 784 A R + G + D+ + + Sbjct: 816 -------------------------AEPQYPVRSAAPHPGDIGDFINEGLKA-------- 842 Query: 785 EKAYAYADEDEGRPANDCLLIYDHEGVGSPVGSIGC--CSWIVDDLDESCMETLDPKFRT 842 AD D P D LL++D+EG GS GS+ S + D + P+F+ Sbjct: 843 ------ADNDPTAPPYDSLLVFDYEGSGSTAGSLSSLNSSSSGGEQDYDYLNDWGPRFKK 896 Query: 843 LAEI 846 LA++ Sbjct: 897 LADM 900 >gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo sapiens] Length = 839 Score = 310 bits (794), Expect = 5e-84 Identities = 196/619 (31%), Positives = 308/619 (49%), Gaps = 35/619 (5%) Query: 39 TKWQTVRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYG 98 T+ +RR KR W + +E + ++ SD N + Y ISG G+D+ P Sbjct: 125 TRETVLRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGVDKEPLN 184 Query: 99 VFTINPRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFS 158 +F I TG + T VDRE +F + A + G + PL L ++V D NDN PVF+ Sbjct: 185 LFYIERDTGNLFCTRPVDREEYDVFDLIAYASTADGYSADLPLPLPIRVEDENDNHPVFT 244 Query: 159 QSVYTASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEPSGAPMFILNRYTGEV 218 +++Y + E+S T V +CATD DE + +++++ Y I+ Q P +F ++ TG + Sbjct: 245 EAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTPRSPGLFSVHPSTGVI 304 Query: 219 CTMSSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASI 278 T+S +LDRE Y+L+++ D DG GL C I V D NDN PT + +Y A + Sbjct: 305 TTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDNAPTFRQNAYEAFV 364 Query: 279 EENCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLD 338 EEN + E++R+ D D T NW + IL GN+ F I TD +TNEG+L VVK L+ Sbjct: 365 EENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKETNEGVLSVVKPLN 424 Query: 339 YEQAPNIQLSIGVKNQADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGI 398 YE+ + L IGV N+A F + ++ V + V D+ EGP P+ ++E + Sbjct: 425 YEENRQVNLEIGVNNEAPFARDIPRVTALNRALVTVHVRDLDEGPECTPAAQYVRIKENL 484 Query: 399 KGSSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKSKY 458 S +N Y A D + N +RY HD W+ ID +G I S+ D++ + Sbjct: 485 AVGSKIN----GYKAYDPENRN-GNGLRYKKLHDPKGWITIDEISGSIITSKILDREVET 539 Query: 459 IINGIYTAEILAIDDGSGKTATGTICIEVPDINDYCPNIFPERRTICID----SPSVLIS 514 N +Y +LAID ++ TGT+ + + D+ND P I E IC + + + Sbjct: 540 PKNELYNITVLAIDK-DDRSCTGTLAVNIEDVNDNPPEILQEYVVICKPKMGYTDILAVD 598 Query: 515 VNEHSYGSPFTFCVVDEPPGIADMWDVRSTNATSAILTAKQVLSPGFYEIPILVKDSYNR 574 +E +G+PF F + + P I+ +W + N T+A L+ ++ Y IPI VKD + Sbjct: 599 PDEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNAGFQEYTIPITVKDRAGQ 658 Query: 575 ACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVSNVGLGPAGIG 634 A +++++ C+C C + + + V LG I Sbjct: 659 AA--TKLLRVNLCECTHPTQCRATSRS----------------------TGVILGKWAIL 694 Query: 635 MMVLGILLLILAPLLLLLC 653 ++LGI LL + LL L+C Sbjct: 695 AILLGIALL-FSVLLTLVC 712 >gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens] Length = 840 Score = 303 bits (775), Expect = 7e-82 Identities = 206/623 (33%), Positives = 311/623 (49%), Gaps = 39/623 (6%) Query: 39 TKWQTVRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYG 98 TK ++R KR W A+ E + +I+SD N I Y ISG G+D+ P+ Sbjct: 124 TKDTALKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDAAQNYTIFYSISGPGVDKEPFN 183 Query: 99 VFTINPRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFS 158 +F I TG+I T +DRE F +Y A + G E PL L +K+ D NDNAP F Sbjct: 184 LFYIEKDTGDIFCTRSIDREKYEQFALYGYATTADGYAPEYPLPLIIKIEDDNDNAPYFE 243 Query: 159 QSVYTASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEPSGAPMFILNRYTGEV 218 V ++ EN + T V K+ ATD DE + L++++ YKI+ Q P F ++ TG + Sbjct: 244 HRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHTRLKYKILQQIPDHPKHFSIHPDTGVI 303 Query: 219 CTMSSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASI 278 T + FLDRE+ Y L++ D G GL + I + D NDN P+ +TSY + Sbjct: 304 TTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTGTITISLEDENDNPPSFTETSYVTEV 363 Query: 279 EENCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLD 338 EEN + E++R++ D D T + A Y IL GN+ F I TDP TNEG+L VVK L+ Sbjct: 364 EENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGNENGNFIISTDPNTNEGVLCVVKPLN 423 Query: 339 YEQAPNIQLSIGVKNQADFHYSVASQF-QMHPTPVRIQVVDVREGPAFHPSTMAFSVREG 397 YE + L +GV N+A F + +SQ M T V ++++D EGP HP ++G Sbjct: 424 YEVNRQVILQVGVINEAQFSKAASSQTPTMCTTTVTVKIIDSDEGPECHPPVKVIQSQDG 483 Query: 398 I-KGSSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKS 456 G LL Y A+D + + +RY D +W +I+ TG+++ + D++S Sbjct: 484 FPAGQELLG-----YKALDPEISS-GEGLRYQKLGDEDNWFEINQHTGDLRTLKVLDRES 537 Query: 457 KYIINGIYTAEILAIDDGSGKTATGTICIEVPDINDYCPNIFPERRTICIDSP--SVLIS 514 K++ N Y ++A+ D G++ TGT+ + + D ND+ P I E TIC ++ +VL Sbjct: 538 KFVKNNQYNISVVAV-DAVGRSCTGTLVVHLDDYNDHAPQIDKE-VTICQNNEDFAVLKP 595 Query: 515 VNEH--SYGSPFTFCVVDEPPGIADMWDVRSTNATSAILTAKQVLSPGFYEIPILVKDSY 572 V+ G PF F + + + W++ + +AIL +Q L +Y +PI +KD + Sbjct: 596 VDPDGPENGPPFQFFLDN---SASKNWNIEEKDGKTAILRQRQNLDYNYYSVPIQIKDRH 652 Query: 573 NRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVSNVGLGPAG 632 M+ + CDC C + T D+ NV LG Sbjct: 653 GLVA--THMLTVRVCDCSTPSECRMKDKS---TRDVR--------------PNVILGRWA 693 Query: 633 IGMMVLGILLLILAPLLLLLCCC 655 I MVLG +LL+ +L C C Sbjct: 694 ILAMVLGSVLLL---CILFTCFC 713 >gi|4826669 cadherin 15 preproprotein [Homo sapiens] Length = 814 Score = 301 bits (771), Expect = 2e-81 Identities = 231/815 (28%), Positives = 381/815 (46%), Gaps = 91/815 (11%) Query: 46 RQKREWIKFAAACREGEDNSKR--NPIAKIRSDCESNQKITYRISGVGIDRPPYGVFTIN 103 R +R W+ + E N KR P+ +I+SD + + Y I G G+D P GVF+I+ Sbjct: 42 RVRRAWVIPPISVSE---NHKRLPYPLVQIKSDKQQLGSVIYSIQGPGVDEEPRGVFSID 98 Query: 104 PRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFSQSVYT 163 TG++ + +++DRE T F + AL+ G LE P +L + V+D NDN P F Q +T Sbjct: 99 KFTGKVFLNAMLDREKTDRFRLRAFALDLGGSTLEDPTDLEIVVVDQNDNRPAFLQEAFT 158 Query: 164 ASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEPSGAP-MFILNRYTGEVCTMS 222 + E + T V + ATDAD+ N+ + + I+ Q G+P +F ++ TGE+ T+ Sbjct: 159 GRVLEGAVPGTYVTRAEATDADDPETDNAALRFSILQQ---GSPELFSIDELTGEIRTVQ 215 Query: 223 SFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEENC 282 LDRE ++YNL ++ +D G DGL++ I + D+NDN P + + E Sbjct: 216 VGLDREVVAVYNLTLQVADMSG--DGLTATASAIITLDDINDNAPEFTRDEFFMEAIEAV 273 Query: 283 LSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYEQA 342 ++ RL+ D D G+ NW+A++ IL G+ F I+TDP+TNEG+L +VK LDYE Sbjct: 274 SGVDVGRLEVEDRDLPGSPNWVARFTILEGDPDGQFTIRTDPKTNEGVLSIVKALDYESC 333 Query: 343 PNIQLSIGVKNQADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGIKGSS 402 + +L + V+N+A + A + + VR+ V D E P F + + S+ EG + Sbjct: 334 EHYELKVSVQNEAPLQ-AAALRAERGQAKVRVHVQDTNEPPVFQENPLRTSLAEGAPPGT 392 Query: 403 LLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKSKYIING 462 L + T++A D DT + Y +D WL++D+ TG IQ S ++ G Sbjct: 393 L----VATFSARDPDT-EQLQRLSYSKDYDPEDWLQVDAATGRIQTQHVLSPASPFLKGG 447 Query: 463 IYTAEILAIDDGS-GKTATGTICIEVPDINDYCPNIF-PERRTICID---SPSVLISVNE 517 Y A +LA DD S +TATGT+ IE+ ++ND+ P + P ++C + P +L+ + Sbjct: 448 WYRAIVLAQDDASQPRTATGTLSIEILEVNDHAPVLAPPPPGSLCSEPHQGPGLLLGATD 507 Query: 518 HS---YGSPFTFCVVDEPPGIADMWDVRSTNATSAILTAKQVLSPGFYEIPILVKDSYNR 574 +G+PF F + P + W + N + A L + + G + + +L++DS Sbjct: 508 EDLPPHGAPFHFQLSPRLPELGRNWSLSQVNVSHARLRPRHQVPEGLHRLSLLLRDSGQP 567 Query: 575 ACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVSNVGLGPAGIG 634 + Q + + C C + +CL AA + AG + + LG + Sbjct: 568 PQQREQPLNVTVCRCGKDGVCLPGAAALL-----------------AGGTGLSLG--ALV 608 Query: 635 MMVLGILLLILAPLLLLLCCCKQRQPEGLGTRFAPVPEGGEGVMQSWRIEGAHPEDRDVS 694 +++ LLL++ LL+ L +Q G G P + + V+ ++ +G ED+D Sbjct: 609 IVLASALLLLVLVLLVALRARFWKQSRGKGLLHGPQDDLRDNVL-NYDEQGGGEEDQDAY 667 Query: 695 NICAPMTASNTQDRMDSSEIYTNTYAAGGTVEGGVSGVELNTGMGTAVGLMAAGAAGASG 754 +I S + T + +G Sbjct: 668 DI---------------------------------SQLRHPTALSLPLG----------P 684 Query: 755 AARKRSSTMGTLRDYADADINMAFLD-SYFSEKAYAYADEDEGRPANDCLLIYDHEGVGS 813 +R + G L + + LD + F AD D P D LIYD+EG GS Sbjct: 685 PPLRRDAPQGRLHPQPPRVLPTSPLDIADFINDGLEAADSDPSVPPYDTALIYDYEGDGS 744 Query: 814 PVGSIG--CCSWIVDDLDESCMETLDPKFRTLAEI 846 G++ S +D D + P+F LA++ Sbjct: 745 VAGTLSSILSSQGDEDQDYDYLRDWGPRFARLADM 779 >gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens] Length = 882 Score = 295 bits (756), Expect = 1e-79 Identities = 244/820 (29%), Positives = 378/820 (46%), Gaps = 110/820 (13%) Query: 44 VRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYGVFTIN 103 +RRQKR+W+ +C E E + +I+S+ + K+ Y I+G G D PP GVF I Sbjct: 149 LRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIE 208 Query: 104 PRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFSQSVYT 163 TG + +T +DRE + ++ A++S G +E P+E+ + V D NDN P F+Q V+ Sbjct: 209 RETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFK 268 Query: 164 ASIEENSDANTLVVKLCATDADEE-NHLNSKIAYKIVSQEPS--GAPMFILNRYTGEVCT 220 S+ E + T V+++ ATDAD++ N N+ IAY I+SQ+P MF +NR TG + Sbjct: 269 GSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISV 328 Query: 221 MSSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEE 280 +++ LDRE Y LVV+ +D G +GLS+ I V D NDN P T+Y + E Sbjct: 329 VTTGLDRESFPTYTLVVQAADLQG--EGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPE 386 Query: 281 NCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYE 340 N + + L+ D D T W A Y IL+ +DG F + T+P N+GILK K LD+E Sbjct: 387 NEANVVITTLKVTDADAPNTPAWEAVYTILN-DDGGQFVVTTNPVNNDGILKTAKGLDFE 445 Query: 341 QAPNIQLSIGVKNQADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGIKG 400 L + V N F S+ + V + V+DV E P F P V E Sbjct: 446 AKQQYILHVAVTNVVPFEVSLTTS----TATVTVDVLDVNEAPIFVPPEKRVEVSEDFG- 500 Query: 401 SSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKS-KYI 459 + + +YTA + DT + Y I D +WL+I+ TG I E D++ +++ Sbjct: 501 ---VGQEITSYTAQEPDT-FMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHV 556 Query: 460 INGIYTAEILAIDDGSG-KTATGTICIEVPDINDYCPNIFPERRTI--CIDSPSV----L 512 N YTA I+A D+GS T TGT+ + + D+ND P PE RTI C +P + Sbjct: 557 KNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAP--IPEPRTIFFCERNPKPQVINI 614 Query: 513 ISVNEHSYGSPFTFCVVDEPPGIADMWDVRSTNAT--SAILTAKQVLSPGFYEIPILVKD 570 I + SPFT + G + W ++ + T S IL K L G Y+I + + D Sbjct: 615 IDADLPPNTSPFT---AELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMD 671 Query: 571 SYNRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVSNVGLGP 630 + N+ + +++ CDC+ GAAG+ + PV +AG+ P Sbjct: 672 NQNK--DQVTTLEVSVCDCE--------GAAGVCRK------AQPV---EAGLQI----P 708 Query: 631 AGIGMM--VLGILLLILAPLLLLLCCCKQRQPEGLGTRFAPVPEGGEGVMQSWRIEGAHP 688 A +G++ +L +L+LIL LL L ++P P + + + EG Sbjct: 709 AILGILGGILALLILILLLLLFLRRRAVVKEP------LLPPEDDTRDNVYYYDEEGGGE 762 Query: 689 EDRDVSNICAPMTASNTQDRMDSSEIYTNTYAAGGTVEGGVSGVELNTGMGTAVGLMAAG 748 ED+D D S+++ A V Sbjct: 763 EDQD----------------FDLSQLHRGLDARPEVTRNDV------------------- 787 Query: 749 AAGASGAARKRSSTMGTLRDYADADINMAFLDSYFSEKAYAYADEDEGRPANDCLLIYDH 808 + T+ ++ Y N + ++ E A AD D P D LL++D+ Sbjct: 788 -----------APTLMSVPRYLPRPANPDEIGNFIDENLKA-ADTDPTAPPYDSLLVFDY 835 Query: 809 EGVGSPVGSIGCCSWIVDDLDE--SCMETLDPKFRTLAEI 846 EG GS S+ + D D+ + +F+ LA++ Sbjct: 836 EGSGSEAASLSSLNSSESDKDQDYDYLNEWGNRFKKLADM 875 >gi|4502719 cadherin 13 preproprotein [Homo sapiens] Length = 713 Score = 278 bits (712), Expect = 1e-74 Identities = 183/577 (31%), Positives = 291/577 (50%), Gaps = 34/577 (5%) Query: 44 VRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYGVFTIN 103 V RQKR + E + + K+ D + ++ +R++G G+D+ P G+F IN Sbjct: 133 VPRQKRSIVVSPILIPENQRQPFPRDVGKV-VDSDRPERSKFRLTGKGVDQEPKGIFRIN 191 Query: 104 PRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFSQSVYT 163 TG +++T +DRE+ ++ ++ + G+ LE P+ L V V+D NDN P+F + Y Sbjct: 192 ENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRPIFREGPYI 251 Query: 164 ASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEPS--GAPMFILNRYTGEVCTM 221 + E S T V+++ A DAD+ N+ + Y I Q P MF ++ G++ T+ Sbjct: 252 GHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGDIVTV 311 Query: 222 SS--FLDRE--QHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSAS 277 S LDRE ++ Y L++ D G GL+ I + D ND+ P K + A+ Sbjct: 312 VSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEFQAT 371 Query: 278 IEENCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKML 337 +EE + ++ L D D+ T W A Y I++GN G F+I T+PQTNEG+L VVK L Sbjct: 372 VEEGAV-GVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPL 430 Query: 338 DYEQAPNIQLSIGVKNQ----ADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFS 393 DYE + L I V+N+ D Y +S +H I V+DV EGP F+P M + Sbjct: 431 DYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVH-----ITVLDVNEGPVFYPDPMMVT 485 Query: 394 VREGIKGSSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFD 453 +E + S VL T A D D+ T +RY + D WL I+ G + + D Sbjct: 486 RQEDLSVGS----VLLTVNATDPDSLQHQT-IRYSVYKDPAGWLNINPINGTVDTTAVLD 540 Query: 454 KKSKYIINGIYTAEILAIDDGS-GKTATGTICIEVPDINDYCPNIFPERRTICIDSPSVL 512 ++S ++ N +YTA LAID G+ T TGT+ I + D+ND P I+P +C D+ ++ Sbjct: 541 RESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFIYPTVAEVCDDAKNLS 600 Query: 513 ISV------NEHSYGSPFTFCVVDEPPGIAD-MWDVRSTNATSAILTAKQVLSPGFYEIP 565 + + + H PF F + + D +W + N T A+++ Q L+ Y +P Sbjct: 601 VVILGASDKDLHPNTDPFKFEI--HKQAVPDKVWKISKINNTHALVSLLQNLNKANYNLP 658 Query: 566 ILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGAAG 602 I+V DS +++ C C ++ +D AAG Sbjct: 659 IMVTDSGKPPMTNITDLRVQVCSCRNSK--VDCNAAG 693 >gi|29570800 cadherin-like 26 isoform a [Homo sapiens] Length = 832 Score = 272 bits (695), Expect = 1e-72 Identities = 184/617 (29%), Positives = 301/617 (48%), Gaps = 39/617 (6%) Query: 9 ICLLIILMVVMEVNSEFIVEVKEFDIENGTTK--WQTVRRQKREWIKFAAACREGEDNSK 66 + LL++L+ +++V+ V+ + D+ T + +Q +RR KR W+ E + Sbjct: 12 LLLLVLLLWLLQVSIIDSVQQETDDLTKQTKEKIYQPLRRSKRRWVITTLELEEEDPGPF 71 Query: 67 RNPIAKIRSDCESNQKITYRISGVGIDR-PPYGVFTINPR-TGEINITSVVDREITPLFL 124 I ++ ++ N + Y ISG G+D P G+F++ G I + VDRE+TP F Sbjct: 72 PKLIGELFNNMSYNMSLMYLISGPGVDEYPEIGLFSLEDHENGRIYVHRPVDREMTPSFT 131 Query: 125 IYCRALN-SRGEDLERPLELRVKVMDINDNAPVFSQSVYTASIEENSDANTLVVKLCATD 183 +Y + S G+ ++ L +++ D+ND+AP F + + +++EN A + ++ A D Sbjct: 132 VYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPEKEFNITVQENQSAGQPIFQMLAVD 191 Query: 184 ADEENHLNSKIAYKIVSQEP----SGAPMFILNRYTGEVCTMSSFLDREQHSMYNLVVRG 239 DEEN NS++ Y ++SQ P SG F ++R +GE+ +S LD E + L++R Sbjct: 192 LDEENTPNSQVLYFLISQTPLLKESG---FRVDRLSGEI-RLSGCLDYETAPQFTLLIRA 247 Query: 240 SDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEENCLSSELIRLQAIDLDEEG 299 RD LSS + V + N++ P + +Y I E S ++RL D D Sbjct: 248 --RDCGEPSLSSTTTVHVDVQEGNNHRPAFTQENYKVQIPEGRASQGVLRLLVQDRDSPF 305 Query: 300 TDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYEQAPNIQLSIGVKNQADFHY 359 T W A++ IL GN+ FDI TDP+TNEGIL V+K LDYE P L I V+N+ + Sbjct: 306 TSAWRAKFNILHGNEEGHFDISTDPETNEGILNVIKPLDYETRPAQSLIIVVENEERLVF 365 Query: 360 SVASQFQ-----MHPTPVRIQVVDVREGPAFHPSTMAFSVREGIKGSSLLNYVLGTYTAI 414 + Q V +QV D + PAFHP + + EG + +L LGT+ A+ Sbjct: 366 CERGKLQPPRKAAASATVSVQVTDANDPPAFHPQSFIVNKEEGARPGTL----LGTFNAM 421 Query: 415 DLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKSKYIINGIYTAEILAIDDG 474 D P + +RY + HD +W+ +D +G + D++S ++ N Y I A+DDG Sbjct: 422 D-----PDSQIRYELVHDPANWVSVDKNSGVVITVEPIDRESPHVNNSFYVIIIHAVDDG 476 Query: 475 -SGKTATGTICIEVPDINDYCPNIFPERR--TICIDSPSVLISVNEHS-----YGSPFTF 526 +TATGT+ + + DIND P + P R +C + + + + PFTF Sbjct: 477 FPPQTATGTLMLFLSDINDNVPTLRPRSRYMEVCESAVHEPLHIEAEDPDLEPFSDPFTF 536 Query: 527 CVVDEPPGIADMWDVRSTNATSAILTAKQVLSPGFYEIPILVKDSYNRACELAQMVQLYA 586 + + D W + S L + L G Y +P+ + D + Q V + Sbjct: 537 ELDNTWGNAEDTWKLGRNWGQSVELLTLRSLPRGNYLVPLFIGD--KQGLSQKQTVHVRI 594 Query: 587 CDCDDNHMCLDSGAAGI 603 C C C++ A + Sbjct: 595 CPCASGLTCVELADAEV 611 >gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens] Length = 829 Score = 266 bits (679), Expect = 1e-70 Identities = 173/557 (31%), Positives = 284/557 (50%), Gaps = 29/557 (5%) Query: 44 VRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQKITYRISGVGIDRPPYGVFTIN 103 +RR KR+W+ + E + +++S+ + + KI Y I+G G D PP GVF + Sbjct: 102 LRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDRDTKIFYSITGPGADSPPEGVFAVE 161 Query: 104 PRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFSQSVYT 163 TG + + +DRE + ++ A++ G +E P+ + + V D ND+ P F+Q + Sbjct: 162 KETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNISIIVTDQNDHKPKFTQDTFR 221 Query: 164 ASIEENSDANTLVVKLCATDADEENHL-NSKIAYKIVSQEPSGAP--MFILNRYTGEVCT 220 S+ E T V+++ ATD D+ + N +AY I SQEP MF ++R TG + Sbjct: 222 GSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTISV 281 Query: 221 MSSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEE 280 +SS LDRE+ Y L ++ +D DG DG ++ +++LD NDN P + Y A + E Sbjct: 282 ISSGLDREKVPEYTLTIQATDMDG--DGSTTTAVAVVEILDANDNAPMFDPQKYEAHVPE 339 Query: 281 NCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYE 340 N + E+ RL DLD + W A YLI+ G+DG+ F I T P++N+GIL K LD+E Sbjct: 340 NAVGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRKGLDFE 399 Query: 341 QAPNIQLSIGVKNQADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGIKG 400 L + V N+A F + + + + V DV E P F P + V+EGI Sbjct: 400 AKNQHTLYVEVTNEAPFVLKLPTS----TATIVVHVEDVNEAPVFVPPSKVVEVQEGIPT 455 Query: 401 SSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKK-SKYI 459 + YTA D D N + Y I D WL +D +G++ D++ +++ Sbjct: 456 GE----PVCVYTAEDPDKEN--QKISYRILRDPAGWLAMDPDSGQVTAVGTLDREDEQFV 509 Query: 460 INGIYTAEILAIDDGS-GKTATGTICIEVPDINDYCPNIFPERRTICIDSP-SVLISVNE 517 N IY +LA+D+GS T TGT+ + + D+ND+ P P + TIC SP ++++ + Sbjct: 510 RNNIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGPVPEPRQITICNQSPVRQVLNITD 569 Query: 518 HS---YGSPFTFCVVDEPPGIADMWDVRSTN--ATSAILTAKQVLSPGFYEIPILVKDSY 572 + SPF + D+ +D++ N + +L+ K+ L Y++ + + D Sbjct: 570 KDLSPHTSPFQAQLTDD----SDIYWTAEVNEEGDTVVLSLKKFLKQDTYDVHLSLSDHG 625 Query: 573 NRACELAQMVQLYACDC 589 N+ E +++ CDC Sbjct: 626 NK--EQLTVIRATVCDC 640 Score = 31.2 bits (69), Expect = 5.3 Identities = 17/58 (29%), Positives = 29/58 (50%), Gaps = 2/58 (3%) Query: 791 ADEDEGRPANDCLLIYDHEGVGSPVGSIGCCSWIVDDLDE--SCMETLDPKFRTLAEI 846 A+ D P D LL++D+EG GS S+ + D D+ + +F+ LA++ Sbjct: 765 ANTDPTAPPYDTLLVFDYEGSGSDAASLSSLTSSASDQDQDYDYLNEWGSRFKKLADM 822 >gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens] Length = 790 Score = 195 bits (495), Expect = 2e-49 Identities = 188/690 (27%), Positives = 303/690 (43%), Gaps = 69/690 (10%) Query: 44 VRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQ-KITYRISGVGIDRPPYGVFTI 102 + R KR W+ E S + K+ SD + + Y +SG G +F I Sbjct: 48 LNRSKRSWMWNQFFLLEEYTGSDYQYVGKLHSDQDRGDGSLKYILSGDGAG----DLFII 103 Query: 103 NPRTGEINITSVVDREITPLFLIYCRALNSR-GEDLERPLELRVKVMDINDNAPVFSQSV 161 N TG+I T +DRE P++++ +A+N R G +E E +K+ DINDN P+F++ V Sbjct: 104 NENTGDIQATKRLDREEKPVYILRAQAINRRTGRPVEPESEFIIKIHDINDNEPIFTKEV 163 Query: 162 YTASIEENSDANTLVVKLCATDADEENHLNS-KIAYKIVSQEPSGAPMFILNRYTGEVCT 220 YTA++ E SD T VV++ ATDAD+ + NS K+ Y I+ G P F + TG + T Sbjct: 164 YTATVPEMSDVGTFVVQVTATDADDPTYGNSAKVVYSIL----QGQPYFSVESETGIIKT 219 Query: 221 MSSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEE 280 +DRE Y +V++ D G GLS I + DVNDN P +++Y E Sbjct: 220 ALLNMDRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQSTYQFKTPE 279 Query: 281 NCLSSELI-RLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDY 339 + I R++A D D +N +Y I G + FD+ TD +T EGI+ V K+LD+ Sbjct: 280 SSPPGTPIGRIKASDADV--GENAEIEYSITDGEGLDMFDVITDQETQEGIITVKKLLDF 337 Query: 340 EQAPNIQLSIGVKN-QADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGI 398 E+ L + N + + F+ T VRI V DV E P F +RE Sbjct: 338 EKKKVYTLKVEASNPYVEPRFLYLGPFKDSAT-VRIVVEDVDEPPVFSKLAYILQIRE-- 394 Query: 399 KGSSLLNYVLGTYTAIDLDTG-NPATDVRYIIGH--DAGSWLKIDSRTGEIQFSREFDKK 455 + +N +G+ TA D D NP V+Y + D IDS G I S+ D++ Sbjct: 395 --DAQINTTIGSVTAQDPDAARNP---VKYSVDRHTDMDRIFNIDSGNGSIFTSKLLDRE 449 Query: 456 SKYIINGIYTAEILAIDDGSGKTATGT-ICIEVPDINDYCPNIFPERRTICIDSPSV--- 511 + N ++A + + K ++ + I+V D+ND P T + Sbjct: 450 TLLWHN----ITVIATEINNPKQSSRVPLYIKVLDVNDNAPEFAEFYETFVCEKAKADQL 505 Query: 512 -----LISVNEHSYGSPFTFCVVDEPPGIADMWDVRSTNATSAILTAKQVLS---PGFYE 563 + ++ G F+F + E ++ + + T+ ILT K + Y Sbjct: 506 IQTLHAVDKDDPYSGHQFSFSLAPEAASGSNFTIQDNKDNTAGILTRKNGYNRHEMSTYL 565 Query: 564 IPILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGV 623 +P+++ D+ V + C C D+H + S A +A + Sbjct: 566 LPVVISDNDYPVQSSTGTVTVRVCAC-DHHGNMQSCHA------------------EALI 606 Query: 624 SNVGLGPAGIGMMVLGILLLILAPLLLLLCCCKQRQPEGLGTRFAPVPEGGEGVMQSWRI 683 GL + ++L I++L L ++L +QR+ E L + + + S+ Sbjct: 607 HPTGLSTGALVAILLCIVIL-LVTVVLFAALRRQRKKEPLIISKEDIRDN----IVSYND 661 Query: 684 EGAHPEDR---DVSNICAPMTASNTQDRMD 710 EG ED D+ + P + + R D Sbjct: 662 EGGGEEDTQAFDIGTLRNPEAIEDNKLRRD 691 Score = 31.2 bits (69), Expect = 5.3 Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 2/57 (3%) Query: 792 DEDEGRPANDCLLIYDHEGVGSPVGSIGCCSWIVDDLDE--SCMETLDPKFRTLAEI 846 D D P D L Y +EG GS S+ + D D+ + P+F+ LA++ Sbjct: 724 DTDPTAPPYDSLATYAYEGTGSVADSLSSLESVTTDADQDYDYLSDWGPRFKKLADM 780 >gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens] Length = 785 Score = 194 bits (494), Expect = 3e-49 Identities = 177/637 (27%), Positives = 284/637 (44%), Gaps = 61/637 (9%) Query: 46 RQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQ-KITYRISGVGIDRPPYGVFTINP 104 R KR W+ E S + K+ SD + I Y +SG G +F I+ Sbjct: 44 RTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGAS----SIFIIDE 99 Query: 105 RTGEINITSVVDREITPLFLIYCRALNS-RGEDLERPLELRVKVMDINDNAPVFSQSVYT 163 TG+I+ T +DRE + + +AL+ + +E E +K+ DINDN P F YT Sbjct: 100 NTGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYT 159 Query: 164 ASIEENSDANTLVVKLCATDADEENHLNS-KIAYKIVSQEPSGAPMFILNRYTGEVCTMS 222 A + E S T VV++ ATDAD+ + NS ++ Y I+ G P F + TG + T Sbjct: 160 AGVPEMSPVGTSVVQVTATDADDPTYGNSARVVYSIL----QGQPYFSVEPKTGVIKTAL 215 Query: 223 SFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEENC 282 +DRE Y LV++ D G GLS + + DVNDN P + SY ++ E+ Sbjct: 216 PNMDREAKDQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESL 275 Query: 283 -LSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYEQ 341 ++S + R++A D D N +Y I+ G+ F I D +T EGI+ + K LD+E Sbjct: 276 PVASVVARIKAADADIGA--NAEMEYKIVDGDGLGIFKISVDKETQEGIITIQKELDFEA 333 Query: 342 APNIQLSIGVKNQ-ADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGIKG 400 + L I N+ AD + F T V+I V DV E P F V E Sbjct: 334 KTSYTLRIEAANKDADPRFLSLGPFS-DTTTVKIIVEDVDEPPVFSSPLYPMEVSE---- 388 Query: 401 SSLLNYVLGTYTAIDLDTGNPATDVRYIIGH--DAGSWLKIDSRTGEIQFSREFDKKSKY 458 ++ + ++GT A D D+ N + VRY I D + ID+ +G I ++ D+++ Sbjct: 389 ATQVGNIIGTVAAHDPDSSN--SPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRET-- 444 Query: 459 IINGIYTAEILAID-DGSGKTATGTICIEVPDINDYCPNIFPE-RRTICIDS-PSVLI-- 513 N I+ +LA++ + G + I + DIND P + T+C ++ P +I Sbjct: 445 --NAIHNITVLAMESQNPSQVGRGYVAITILDINDNAPEFAMDYETTVCENAQPGQVIQK 502 Query: 514 ----SVNEHSYGSPFTFCVVDEPPGIADMWDVRSTNATSAILTAKQVL---SPGFYEIPI 566 +E S G F F + + + + + T++ILT + Y +PI Sbjct: 503 ISAVDKDEPSNGHQFYFSLTTDATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVYYLPI 562 Query: 567 LVKDSYNRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVSNV 626 + DS + + + + CDCD D +A V Sbjct: 563 FIVDSGSPSLSSTNTLTIRVCDCD-------------------ADGVAQTCNAEAYVLPA 603 Query: 627 GLGPAGIGMMVLGILLLILAPLLLLLCCCKQRQPEGL 663 GL + ++ +L L++ L+LL+ ++R+ E L Sbjct: 604 GLSTGALIAILACVLTLLV--LILLIVTMRRRKKEPL 638 >gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens] Length = 785 Score = 194 bits (494), Expect = 3e-49 Identities = 177/637 (27%), Positives = 284/637 (44%), Gaps = 61/637 (9%) Query: 46 RQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQ-KITYRISGVGIDRPPYGVFTINP 104 R KR W+ E S + K+ SD + I Y +SG G +F I+ Sbjct: 44 RTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILSGEGAS----SIFIIDE 99 Query: 105 RTGEINITSVVDREITPLFLIYCRALNS-RGEDLERPLELRVKVMDINDNAPVFSQSVYT 163 TG+I+ T +DRE + + +AL+ + +E E +K+ DINDN P F YT Sbjct: 100 NTGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVIKIQDINDNEPKFLDGPYT 159 Query: 164 ASIEENSDANTLVVKLCATDADEENHLNS-KIAYKIVSQEPSGAPMFILNRYTGEVCTMS 222 A + E S T VV++ ATDAD+ + NS ++ Y I+ G P F + TG + T Sbjct: 160 AGVPEMSPVGTSVVQVTATDADDPTYGNSARVVYSIL----QGQPYFSVEPKTGVIKTAL 215 Query: 223 SFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEENC 282 +DRE Y LV++ D G GLS + + DVNDN P + SY ++ E+ Sbjct: 216 PNMDREAKDQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVNDNPPRFPRRSYQYNVPESL 275 Query: 283 -LSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYEQ 341 ++S + R++A D D N +Y I+ G+ F I D +T EGI+ + K LD+E Sbjct: 276 PVASVVARIKAADADIGA--NAEMEYKIVDGDGLGIFKISVDKETQEGIITIQKELDFEA 333 Query: 342 APNIQLSIGVKNQ-ADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGIKG 400 + L I N+ AD + F T V+I V DV E P F V E Sbjct: 334 KTSYTLRIEAANKDADPRFLSLGPFS-DTTTVKIIVEDVDEPPVFSSPLYPMEVSE---- 388 Query: 401 SSLLNYVLGTYTAIDLDTGNPATDVRYIIGH--DAGSWLKIDSRTGEIQFSREFDKKSKY 458 ++ + ++GT A D D+ N + VRY I D + ID+ +G I ++ D+++ Sbjct: 389 ATQVGNIIGTVAAHDPDSSN--SPVRYSIDRNTDLERYFNIDANSGVITTAKSLDRET-- 444 Query: 459 IINGIYTAEILAID-DGSGKTATGTICIEVPDINDYCPNIFPE-RRTICIDS-PSVLI-- 513 N I+ +LA++ + G + I + DIND P + T+C ++ P +I Sbjct: 445 --NAIHNITVLAMESQNPSQVGRGYVAITILDINDNAPEFAMDYETTVCENAQPGQVIQK 502 Query: 514 ----SVNEHSYGSPFTFCVVDEPPGIADMWDVRSTNATSAILTAKQVL---SPGFYEIPI 566 +E S G F F + + + + + T++ILT + Y +PI Sbjct: 503 ISAVDKDEPSNGHQFYFSLTTDATNNHNFSLKDNKDNTASILTRRNGFRRQEQSVYYLPI 562 Query: 567 LVKDSYNRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVSNV 626 + DS + + + + CDCD D +A V Sbjct: 563 FIVDSGSPSLSSTNTLTIRVCDCD-------------------ADGVAQTCNAEAYVLPA 603 Query: 627 GLGPAGIGMMVLGILLLILAPLLLLLCCCKQRQPEGL 663 GL + ++ +L L++ L+LL+ ++R+ E L Sbjct: 604 GLSTGALIAILACVLTLLV--LILLIVTMRRRKKEPL 638 >gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens] Length = 794 Score = 194 bits (493), Expect = 4e-49 Identities = 180/641 (28%), Positives = 289/641 (45%), Gaps = 62/641 (9%) Query: 45 RRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQ-KITYRISGVGIDRPPYGVFTIN 103 +R KR W+ E S+ + K+ SD + + + Y +SG G VFTI+ Sbjct: 50 QRVKRGWVWNQFFVLEEYVGSEPQYVGKLHSDLDKGEGTVKYTLSGDGAGT----VFTID 105 Query: 104 PRTGEINITSVVDREITPLFLIYCRALN-SRGEDLERPLELRVKVMDINDNAPVFSQSVY 162 TG+I+ +DRE P + + +A++ + LE E +KV DINDN P F Y Sbjct: 106 ETTGDIHAIRSLDREEKPFYTLRAQAVDIETRKPLEPESEFIIKVQDINDNEPKFLDGPY 165 Query: 163 TASIEENSDANTLVVKLCATDADEENHLNS-KIAYKIVSQEPSGAPMFILNRYTGEVCTM 221 A++ E S V+++ ATDAD+ + NS ++ Y I+ G P F ++ TG + T Sbjct: 166 VATVPEMSPVGAYVLQVKATDADDPTYGNSARVVYSIL----QGQPYFSIDPKTGVIRTA 221 Query: 222 SSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEEN 281 +DRE Y ++++ D G GL+ I + DVNDN P K+ + + E+ Sbjct: 222 LPNMDREVKEQYQVLIQAKDMGGQLGGLAGTTIVNITLTDVNDNPPRFPKSIFHLKVPES 281 Query: 282 C-LSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYE 340 + S + R++A+D D N +Y I+ G+ GN FDI TD T EG++K+ K LD+E Sbjct: 282 SPIGSAIGRIRAVDPD--FGQNAEIEYNIVPGDGGNLFDIVTDEDTQEGVIKLKKPLDFE 339 Query: 341 QAPNIQLSIGVKN-QADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGIK 399 + N D + A F+ T V+I V+DV E P F V E Sbjct: 340 TKKAYTFKVEASNLHLDHRFHSAGPFKDTAT-VKISVLDVDEPPVFSKPLYTMEVYE--- 395 Query: 400 GSSLLNYVLGTYTAIDLDTGNPATDVRYIIG--HDAGSWLKIDSRTGEIQFSREFDKKSK 457 + + ++G TA DLD G+ A VRY I D S+ ID G I + D++S Sbjct: 396 -DTPVGTIIGAVTAQDLDVGSSA--VRYFIDWKSDGDSYFTIDGNEGTIATNELLDRES- 451 Query: 458 YIINGIYTAEILAIDDGSG-KTATGTICIEVPDINDYCPNI-FPERRTICIDS-PSVLIS 514 Y I+A + T+ I I V D+N++ P I P +C ++ P +I Sbjct: 452 ---TAQYNFSIIASKVSNPLLTSKVNILINVLDVNEFPPEISVPYETAVCENAKPGQIIQ 508 Query: 515 V------NEHSYGSPFTFCVVDEPPGIADMWDVRS-TNATSAILTAKQVLS---PGFYEI 564 + + G F+F + E I + VR N T+ I T + S Y + Sbjct: 509 IVSAADRDLSPAGQQFSFRLSPE-AAIKPNFTVRDFRNNTAGIETRRNGYSRRQQELYFL 567 Query: 565 PILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVS 624 P++++DS + + C CD + L I+ Sbjct: 568 PVVIEDSSYPVQSSTNTMTIRVCRCDSDGTILSCNVEAIFLP------------------ 609 Query: 625 NVGLGPAGIGMMVLGILLLILAPLLLLLCCCKQRQPEGLGT 665 VGL G + +L ++++LA ++L + +Q++ + L T Sbjct: 610 -VGLS-TGALIAILLCIVILLAIVVLYVALRRQKKKDTLMT 648 >gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens] Length = 790 Score = 189 bits (481), Expect = 9e-48 Identities = 207/828 (25%), Positives = 347/828 (41%), Gaps = 110/828 (13%) Query: 46 RQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQ-KITYRISGVGIDRPPYGVFTINP 104 R KR W+ E + K+ S+ + + Y ++G G +F I+ Sbjct: 50 RPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGAGT----IFIIDD 105 Query: 105 RTGEINITSVVDREITPLFLIYCRALNSR-GEDLERPLELRVKVMDINDNAPVFSQSVYT 163 TG+I+ T +DRE ++++ +A++ R + LE E +KV DINDNAP F+ Y Sbjct: 106 TTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGPYI 165 Query: 164 ASIEENSDANTLVVKLCATDADEENHLNS-KIAYKIVSQEPSGAPMFILNRYTGEVCTMS 222 ++ E SD T V+++ ATDAD+ + NS ++ Y I+ G P F ++ TG + T Sbjct: 166 VTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSIL----QGQPYFSVDPKTGVIRTAL 221 Query: 223 SFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEENC 282 +DRE Y++V++ D G GLS I + DVNDN P + Y + E+ Sbjct: 222 HNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVPESA 281 Query: 283 -LSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYEQ 341 + S + +++A D D N Y I++G+ F I TD +T EGIL + K L+YE+ Sbjct: 282 QVGSAVGKIKANDADT--GSNADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNYEK 339 Query: 342 APNIQLSI-GVKNQADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGIKG 400 + L+I G DF +S F+ T ++I V DV E P F + V E K Sbjct: 340 KKSYTLNIEGANTHLDFRFSHLGPFK-DATMLKIIVGDVDEPPLFSMPSYLMEVYENAK- 397 Query: 401 SSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDA--GSWLKIDSRTGEIQFSREFDKKSKY 458 + V+GT A D D+ N VRY I ++ + ID+ TG I+ ++ D++ Sbjct: 398 ---IGTVVGTVLAQDPDSTNSL--VRYFINYNVEDDRFFNIDANTGTIRTTKVLDREETP 452 Query: 459 IINGIYTAEILAIDDGSGKTATGTICIEVPDINDYCPNIFPERRTICIDS--PSVLISV- 515 N TA + D + T+ I V D+ND P + E I ++ P +I Sbjct: 453 WYNITVTASEI---DNPDLLSHVTVGIRVLDVNDNPPELAREYDIIVCENSKPGQVIHTI 509 Query: 516 -----NEHSYGSPFTFCVVDEPPGIADMWDVRSTNATSAILTAKQVLS---PGFYEIPIL 567 ++ + G F F + + P + + + T++ILT ++ S Y +PI+ Sbjct: 510 SATDKDDFANGPRFNFFLDERLPVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYLPIM 569 Query: 568 VKDSYNRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVSNVG 627 + D + + + + C C+ + A +A +S+ G Sbjct: 570 ISDGGIPSLSSSSTLTIRVCACERDGRVRTCHA-------------------EAFLSSAG 610 Query: 628 LGPAGIGMMVLGILLLILAPLLLLLCCCKQRQPEGLGTRFAPVPEGGEGVMQSWRIEGAH 687 L + ++L +L+L+ +++L ++ + E L V E + ++ EG Sbjct: 611 LSTGALIAILLCVLILL--AIVVLFITLRRSKKEPLIISEEDVREN----VVTYDDEGGG 664 Query: 688 PEDRDVSNICAPMTASNTQDRMDSSEIYTNTYAAGGTVEGGVSGVELNTGMGTAVGLMAA 747 ED + +I A S ++ +I Sbjct: 665 EEDTEAFDITALRNPSAAEELKYRRDI--------------------------------- 691 Query: 748 GAAGASGAARKRSSTMGTLRDYADADINMAFLDSYFSEKAYAYADEDEGRPANDCLLIYD 807 R T R + + + + ++ A AD D P D L Y Sbjct: 692 -----------RPEVKLTPRHQTSSTLESIDVQEFIKQR-LAEADLDPSVPPYDSLQTYA 739 Query: 808 HEGVGSPVGSIGC--CSWIVDDLDESCMETLDPKFRTLAEICLNTEIE 853 +EG S GSI + D D + P+F+ LAE+ E E Sbjct: 740 YEGQRSEAGSISSLDSATTQSDQDYHYLGDWGPEFKKLAELYGEIESE 787 >gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens] Length = 801 Score = 184 bits (466), Expect = 5e-46 Identities = 159/573 (27%), Positives = 257/573 (44%), Gaps = 42/573 (7%) Query: 40 KWQTVRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQ-KITYRISGVGIDRPPYG 98 K Q+ +R KR W+ E + + K+ SD + I Y +SG G Sbjct: 50 KPQSHQRTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGAGI---- 105 Query: 99 VFTINPRTGEINITSVVDREITPLFLIYCRALNSR-GEDLERPLELRVKVMDINDNAPVF 157 VFTI+ TG+I+ +DRE + + +AL+ R G +E E +K+ DINDN P F Sbjct: 106 VFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKF 165 Query: 158 SQSVYTASIEENSDANTLVVKLCATDADEENHLNS-KIAYKIVSQEPSGAPMFILNRYTG 216 Y A++ E S T V+++ ATDAD+ + NS ++ Y I+ G P F ++ TG Sbjct: 166 LDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSIL----QGQPYFSVDSKTG 221 Query: 217 EVCTMSSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSA 276 + T +DRE Y ++++ D G GL+ I + DVNDN P + Y Sbjct: 222 VIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQM 281 Query: 277 SIEENC-LSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVK 335 S+ E+ +SS + R+ A DLDE N +Y I+ G+ + FDI TDP GI+ V K Sbjct: 282 SVLESAPISSTVGRVFAKDLDE--GINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKK 339 Query: 336 MLDYEQAPNIQLSI-GVKNQADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSV 394 L +E + L + G + + FQ T V I V DV E P F P V Sbjct: 340 PLSFESKKSYTLKVEGANPHLEMRFLNLGPFQ-DTTTVHISVEDVDEPPVFEPGFYFVEV 398 Query: 395 REGIKGSSLLNYVLGTYTAIDLDTGNPATDVRYII--GHDAGSWLKIDSRTGEIQFSREF 452 E + + + + +A D D N +RY I D G + +D TG + +R Sbjct: 399 PEDVAIGTTIQII----SAKDPDVTN--NSIRYSIDRSSDPGRFFYVDITTGALMTARPL 452 Query: 453 DKKSKYIINGIYTAEILAID-DGSGKTATGTICIEVPDINDYCPNIFPE--RRTICIDSP 509 D++ + +LA++ + + + + I+V D+ND P FP +C ++ Sbjct: 453 DREE----FSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPE-FPRFYEAFVCENAK 507 Query: 510 S-------VLISVNEHSYGSPFTFCVVDEPPGIADMWDVRSTNATSAILTAK---QVLSP 559 + + ++ G F + + E + + + T+ ILT + + Sbjct: 508 AGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTARILTRRSGFRQQEQ 567 Query: 560 GFYEIPILVKDSYNRACELAQMVQLYACDCDDN 592 + +PIL+ DS + + C CDD+ Sbjct: 568 SVFHLPILIADSGQPVLSSTGTLTIQVCSCDDD 600 >gi|16753221 cadherin 22 precursor [Homo sapiens] Length = 828 Score = 179 bits (454), Expect = 1e-44 Identities = 211/824 (25%), Positives = 333/824 (40%), Gaps = 90/824 (10%) Query: 46 RQKREWIKFAAACREGEDNSKRNPIAKIRSDC-ESNQKITYRISGVGIDRPPYGVFTINP 104 R KR W+ E ++ + KI SD E + I Y ISG G +F I+ Sbjct: 59 RVKRGWVWNQFFVVEEYTGTEPLYVGKIHSDSDEGDGAIKYTISGEGAGT----IFLIDE 114 Query: 105 RTGEINITSVVDREITPLFLIYCRALNSRGEDLERP-LELRVKVMDINDNAPVFSQSVYT 163 TG+I+ +DRE + + +A + L P E +KV DIND+ P F Y Sbjct: 115 LTGDIHAMERLDREQKTFYTLRAQARDRATNRLLEPESEFIIKVQDINDSEPRFLHGPYI 174 Query: 164 ASIEENSDANTLVVKLCATDADEENHLNS-KIAYKIVSQEPSGAPMFILNRYTGEVCTMS 222 S+ E S T V+++ A+DAD+ + +S ++ Y ++ G F ++ TG + T Sbjct: 175 GSVAELSPTGTSVMQVMASDADDPTYGSSARLVYSVLD----GEHHFTVDPKTGVIRTAV 230 Query: 223 SFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEENC 282 LDRE Y +V++ +D G GLS I V DVNDN P + Y SI+E+ Sbjct: 231 PDLDRESQERYEVVIQATDMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQKMYQFSIQESA 290 Query: 283 -LSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYEQ 341 + + + R++A D D + S + G+ F + TD T E I+ V K LD+E Sbjct: 291 PIGTAVGRVKAEDSDVGENTDMTYHLKDESSSGGDVFKVTTDSDTQEAIIVVQKRLDFES 350 Query: 342 APNIQLSIGVKNQ-ADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGIKG 400 P + + N+ D ++ F+ VR+ V DV E P F P + V+E + Sbjct: 351 QPVHTVILEALNKFVDPRFADLGTFR-DQAIVRVAVTDVDEPPEFRPPSGLLEVQEDAQV 409 Query: 401 SSLLNYVLGTYTAIDLDTGNPATDVRYIIGH--DAGSWLKIDSRTGEIQFSREFDKKSKY 458 SL +G TA D D N VRY I D ID+ TG I + D+++ Sbjct: 410 GSL----VGVVTARDPDAAN--RPVRYAIDRESDLDQIFDIDADTGAIVTGKGLDRETA- 462 Query: 459 IINGIYTAEILAID-DGSGKTATGTICIEVPDINDYCPNI-FPERRTICIDS-PSVLISV 515 G + +LA++ D + + ++ I + D+ND P + P +C D+ P LI Sbjct: 463 ---GWHNITVLAMEADNHAQLSRASLRIRILDVNDNPPELATPYEAAVCEDAKPGQLIQT 519 Query: 516 ------NEHSYGSPFTFCVVDEPP-----GIADMWDVRSTNATSAILTAKQVLSPGFYEI 564 +E G F F +V E P + D+ D + T + +Q + + Sbjct: 520 ISVVDRDEPQGGHRFYFRLVPEAPSNPHFSLLDIQDNTAAVHTQHVGFNRQ--EQDVFFL 577 Query: 565 PILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVS 624 PILV DS + + C CD + A V Sbjct: 578 PILVVDSGPPTLSSTGTLTIRICGCDSSGTIQSCNTT-------------------AFVM 618 Query: 625 NVGLGPAGIGMMVLGILLLILAPLLLLLCCCKQRQPEGLGTRFAPVPEGGEGVMQSWRIE 684 L P ++ L + +LIL L+LL+ ++ L + E + + E Sbjct: 619 AASLSPG--ALIALLVCVLILVVLVLLILTLRRHHKSHLS---SDEDEDMRDNVIKYNDE 673 Query: 685 GAHPEDRDVSNICAPMTASNTQDRMDSSEIYTNTYAAGGTVEGGVSGVELNTGMGTAVGL 744 G +D + ++ A + + G ++GG G G G G Sbjct: 674 GGGEQDTEAYDMSALRSLYDF-----------------GELKGGDGGGSAGGGAGGGSG- 715 Query: 745 MAAGAAGASGAARKRSSTMGTLRDYADADINMAFLDSYFSEKAYAYADEDEGRPANDCLL 804 G AG+ A S + + + + + S K A AD D P D Sbjct: 716 ---GGAGSPPQAHLPSERHSLPQGPPSPEPDFSVFRDFISRKV-ALADGDLSVPPYDAFQ 771 Query: 805 IYDHEGVGSPVGSIGC--CSWIVDDLDESCMETLDPKFRTLAEI 846 Y EG SP S+ + D + + + P+FR LA + Sbjct: 772 TYAFEGADSPAASLSSLHSGSSGSEQDFAYLSSWGPRFRPLAAL 815 >gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens] Length = 796 Score = 176 bits (445), Expect = 1e-43 Identities = 173/645 (26%), Positives = 281/645 (43%), Gaps = 69/645 (10%) Query: 42 QTVRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQ-KITYRISGVGIDRPPYGVF 100 Q ++R KR W+ E + ++ SD +S I Y +SG G +F Sbjct: 46 QVLQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGAGT----IF 101 Query: 101 TINPRTGEINITSVVDREITPLFLIYCRALN-SRGEDLERPLELRVKVMDINDNAPVFSQ 159 I+ ++G I+ T +DRE + + +A++ LE P E VKV DINDN P F Sbjct: 102 VIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLH 161 Query: 160 SVYTASIEENSDANTLVVKLCATDADEENHLNS-KIAYKIVSQEPSGAPMFILNRYTGEV 218 Y A++ E S+ T V+++ A+DAD+ + NS K+ Y I+ G P F + TG + Sbjct: 162 ETYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSIL----EGQPYFSVEAQTGII 217 Query: 219 CTMSSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASI 278 T +DRE Y++V++ D G GLS I + DVNDN P ++ Y S+ Sbjct: 218 RTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSV 277 Query: 279 EENCLSSELI-RLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKML 337 E + E + R++A D D +N L Y I+ G+ F+I TD +T EG++K+ K + Sbjct: 278 SEAAVPGEEVGRVKAKDPDI--GENGLVTYNIVDGDGMESFEITTDYETQEGVIKLKKPV 335 Query: 338 DYEQAPNIQLSIGVKN-QADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVRE 396 D+E L + N D + F+ T V+I V D E P F + V+E Sbjct: 336 DFETKRAYSLKVEAANVHIDPKFISNGPFKDTVT-VKISVEDADEPPMFLAPSYIHEVQE 394 Query: 397 GIKGSSLLNYVLGTYTAIDLDTGNPATDVRYIIGH--DAGSWLKIDSRTGEIQFSREFDK 454 + V+G A D D N + +RY I D + I+ G I+ ++ D+ Sbjct: 395 NAAAGT----VVGRVHAKDPDAAN--SPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDR 448 Query: 455 KSKYIIN-GIYTAEILAIDDGSGKTATGTICIEVPDINDYCPNI-FPERRTIC------- 505 + +N ++ AEI + A + I V D+ND P P IC Sbjct: 449 EETAWLNITVFAAEI----HNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGFICESDQTKP 504 Query: 506 -IDSPSVLISVNEH---SYGSPFTFCVVDEPPGIA--DMWDVRSTNATSAILTAKQ---- 555 + P V IS ++ + G F F + PP I + VR +A + A++ Sbjct: 505 LSNQPIVTISADDKDDTANGPRFIFSL---PPEIIHNPNFTVRDNRDNTAGVYARRGGFS 561 Query: 556 VLSPGFYEIPILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGP 615 Y +PI++ D + + C CD N L A Sbjct: 562 RQKQDLYLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSCNA--------------- 606 Query: 616 VTEDQAGVSNVGLGPAGIGMMVLGILLLILAPLLLLLCCCKQRQP 660 +A + N GL + ++ I++L++ +L + ++++P Sbjct: 607 ----EAYILNAGLSTGALIAILACIVILLVIVVLFVTLRRQKKEP 647 Score = 36.6 bits (83), Expect = 0.13 Identities = 20/58 (34%), Positives = 29/58 (50%), Gaps = 2/58 (3%) Query: 791 ADEDEGRPANDCLLIYDHEGVGSPVGSIGCCSWIV--DDLDESCMETLDPKFRTLAEI 846 AD D P D + IY +EG GS GS+ DLD ++ P+F+ LA++ Sbjct: 728 ADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESATTDSDLDYDYLQNWGPRFKKLADL 785 >gi|221316595 cadherin 17 precursor [Homo sapiens] Length = 832 Score = 176 bits (445), Expect = 1e-43 Identities = 155/574 (27%), Positives = 247/574 (43%), Gaps = 65/574 (11%) Query: 93 DRPPYGVFTINPRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDIND 152 ++ P F+I+ + G+I +T +DRE ++ Y A + G+ L PLE+ VKV DIND Sbjct: 277 EKLPRFPFSID-QEGDIYVTQPLDREEKDAYVFYAVAKDEYGKPLSYPLEIHVKVKDIND 335 Query: 153 NAPVFSQSVYTASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEPSGAPM---F 209 N P V ++EN + L A D DEEN NS + Y+IV Q P PM F Sbjct: 336 NPPTCPSPVTVFEVQENERLGNSIGTLTAHDRDEENTANSFLNYRIVEQTPK-LPMDGLF 394 Query: 210 ILNRYTGEVCTMSSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTL 269 ++ Y G + L ++ YNL + SD+D + C +I V+D+ND P Sbjct: 395 LIQTYAGMLQLAKQSLKKQDTPQYNLTIEVSDKD-----FKTLCFVQINVIDINDQIPIF 449 Query: 270 EKTSYS--ASIEENCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTN 327 EK+ Y E+ + S ++ +QA D DE T + Y I+ G+ + TDP TN Sbjct: 450 EKSDYGNLTLAEDTNIGSTILTIQATDADEPFTGSSKILYHIIKGDSEGRLGVDTDPHTN 509 Query: 328 EGILKVVKMLDYEQAPNIQLSIGVKNQADFHYSV---ASQFQMHPTPVRIQVVDVREGPA 384 G + + K LD+E A + +N + V AS F + V DV E P Sbjct: 510 TGYVIIKKPLDFETAAVSNIVFKAENPEPLVFGVKYNASSF----AKFTLIVTDVNEAPQ 565 Query: 385 FHPSTMAFSVREGIKGSSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTG 444 F V E + + +G TA D + D+ Y + D WLKID TG Sbjct: 566 FSQHVFQAKVSEDV----AIGTKVGNVTAKDPE----GLDISYSLRGDTRGWLKIDHVTG 617 Query: 445 EIQFSREFDKKSKYIINGIYTAEILAID-DGSGKTATGTICIEVPDINDYCPNIFPERRT 503 EI D+++ Y +++A + GS ++ + + D+ND P + + Sbjct: 618 EIFSVAPLDREA----GSPYRVQVVATEVGGSSLSSVSEFHLILMDVNDNPPRLAKDYTG 673 Query: 504 IC----IDSPSVLI----SVNEHSYGSP-FTFCVVDEPPGIADMWDVRSTNATSAILTAK 554 + + +P LI ++H + P FTF + + + W+V N T A L+ + Sbjct: 674 LFFCHPLSAPGSLIFEATDDDQHLFRGPHFTFSL--GSGSLQNDWEVSKINGTHARLSTR 731 Query: 555 QV-LSPGFYEIPILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTY 613 Y + I + D E + + C C + G + Sbjct: 732 HTEFEEREYVVLIRINDGGRPPLEGIVSLPVTFCSC------------------VEGSCF 773 Query: 614 GPVTEDQAGVSNVGL--GPAGIGMMVLGILLLIL 645 P Q G+ VG+ G ++V+GI+L ++ Sbjct: 774 RPAGH-QTGIPTVGMAVGILLTTLLVIGIILAVV 806 Score = 90.5 bits (223), Expect = 7e-18 Identities = 118/450 (26%), Positives = 189/450 (42%), Gaps = 59/450 (13%) Query: 99 VFTINPRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFS 158 +F I R G + +DRE + AL++ G +E P+ + +KV DINDN P F Sbjct: 69 IFVIE-REGLLYYNRALDRETRSTHNLQVAALDANGIIVEGPVPITIKVKDINDNRPTFL 127 Query: 159 QSVYTASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEP--SGAPMFILNRYTG 216 QS Y S+ +NS + + ATD D+ N ++ Y+IV Q P + F +N TG Sbjct: 128 QSKYEGSVRQNSRPGKPFLYVNATDLDDPATPNGQLYYQIVIQLPMINNVMYFQINNKTG 187 Query: 217 EVCTM---SSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTS 273 + S L+ ++ YNLV+ D G ++ +S D + V +N + K Sbjct: 188 AISLTREGSQELNPAKNPSYNLVISVKDMGGQSE--NSFSDTTSVDIIVTEN---IWKAP 242 Query: 274 YSASIEENCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKV 333 + EN I++ + ++ G AQY ++ F D EG + V Sbjct: 243 KPVEMVENSTDPHPIKITQVRWNDPG-----AQYSLVDKEKLPRFPFSID---QEGDIYV 294 Query: 334 VKMLDYEQAPNIQLSIGVKNQADFHYSVASQFQ----MHPTPVRIQVVDVREGPAFHPST 389 + LD E+ A Y+VA +P + ++V D+ + P PS Sbjct: 295 TQPLDREE-----------KDAYVFYAVAKDEYGKPLSYPLEIHVKVKDINDNPPTCPSP 343 Query: 390 M-AFSVREGIKGSSLLNYVLGTYTAIDLDTGNPATD-VRYIIGHDA------GSWLKIDS 441 + F V+E + L +GT TA D D N A + Y I G +L I + Sbjct: 344 VTVFEVQE----NERLGNSIGTLTAHDRDEENTANSFLNYRIVEQTPKLPMDGLFL-IQT 398 Query: 442 RTGEIQFSREFDKKSKYIINGIYTAEILAIDDGSGKTATGTICIEVPDINDYCPNIFPE- 500 G +Q +++ KK + + + D KT + I V DIND P IF + Sbjct: 399 YAGMLQLAKQSLKKQDTPQYNL----TIEVSDKDFKTLC-FVQINVIDINDQIP-IFEKS 452 Query: 501 ---RRTICIDS--PSVLISVNEHSYGSPFT 525 T+ D+ S ++++ PFT Sbjct: 453 DYGNLTLAEDTNIGSTILTIQATDADEPFT 482 >gi|221316593 cadherin 17 precursor [Homo sapiens] Length = 832 Score = 176 bits (445), Expect = 1e-43 Identities = 155/574 (27%), Positives = 247/574 (43%), Gaps = 65/574 (11%) Query: 93 DRPPYGVFTINPRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDIND 152 ++ P F+I+ + G+I +T +DRE ++ Y A + G+ L PLE+ VKV DIND Sbjct: 277 EKLPRFPFSID-QEGDIYVTQPLDREEKDAYVFYAVAKDEYGKPLSYPLEIHVKVKDIND 335 Query: 153 NAPVFSQSVYTASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEPSGAPM---F 209 N P V ++EN + L A D DEEN NS + Y+IV Q P PM F Sbjct: 336 NPPTCPSPVTVFEVQENERLGNSIGTLTAHDRDEENTANSFLNYRIVEQTPK-LPMDGLF 394 Query: 210 ILNRYTGEVCTMSSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTL 269 ++ Y G + L ++ YNL + SD+D + C +I V+D+ND P Sbjct: 395 LIQTYAGMLQLAKQSLKKQDTPQYNLTIEVSDKD-----FKTLCFVQINVIDINDQIPIF 449 Query: 270 EKTSYS--ASIEENCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTN 327 EK+ Y E+ + S ++ +QA D DE T + Y I+ G+ + TDP TN Sbjct: 450 EKSDYGNLTLAEDTNIGSTILTIQATDADEPFTGSSKILYHIIKGDSEGRLGVDTDPHTN 509 Query: 328 EGILKVVKMLDYEQAPNIQLSIGVKNQADFHYSV---ASQFQMHPTPVRIQVVDVREGPA 384 G + + K LD+E A + +N + V AS F + V DV E P Sbjct: 510 TGYVIIKKPLDFETAAVSNIVFKAENPEPLVFGVKYNASSF----AKFTLIVTDVNEAPQ 565 Query: 385 FHPSTMAFSVREGIKGSSLLNYVLGTYTAIDLDTGNPATDVRYIIGHDAGSWLKIDSRTG 444 F V E + + +G TA D + D+ Y + D WLKID TG Sbjct: 566 FSQHVFQAKVSEDV----AIGTKVGNVTAKDPE----GLDISYSLRGDTRGWLKIDHVTG 617 Query: 445 EIQFSREFDKKSKYIINGIYTAEILAID-DGSGKTATGTICIEVPDINDYCPNIFPERRT 503 EI D+++ Y +++A + GS ++ + + D+ND P + + Sbjct: 618 EIFSVAPLDREA----GSPYRVQVVATEVGGSSLSSVSEFHLILMDVNDNPPRLAKDYTG 673 Query: 504 IC----IDSPSVLI----SVNEHSYGSP-FTFCVVDEPPGIADMWDVRSTNATSAILTAK 554 + + +P LI ++H + P FTF + + + W+V N T A L+ + Sbjct: 674 LFFCHPLSAPGSLIFEATDDDQHLFRGPHFTFSL--GSGSLQNDWEVSKINGTHARLSTR 731 Query: 555 QV-LSPGFYEIPILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTY 613 Y + I + D E + + C C + G + Sbjct: 732 HTEFEEREYVVLIRINDGGRPPLEGIVSLPVTFCSC------------------VEGSCF 773 Query: 614 GPVTEDQAGVSNVGL--GPAGIGMMVLGILLLIL 645 P Q G+ VG+ G ++V+GI+L ++ Sbjct: 774 RPAGH-QTGIPTVGMAVGILLTTLLVIGIILAVV 806 Score = 90.5 bits (223), Expect = 7e-18 Identities = 118/450 (26%), Positives = 189/450 (42%), Gaps = 59/450 (13%) Query: 99 VFTINPRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFS 158 +F I R G + +DRE + AL++ G +E P+ + +KV DINDN P F Sbjct: 69 IFVIE-REGLLYYNRALDRETRSTHNLQVAALDANGIIVEGPVPITIKVKDINDNRPTFL 127 Query: 159 QSVYTASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEP--SGAPMFILNRYTG 216 QS Y S+ +NS + + ATD D+ N ++ Y+IV Q P + F +N TG Sbjct: 128 QSKYEGSVRQNSRPGKPFLYVNATDLDDPATPNGQLYYQIVIQLPMINNVMYFQINNKTG 187 Query: 217 EVCTM---SSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTS 273 + S L+ ++ YNLV+ D G ++ +S D + V +N + K Sbjct: 188 AISLTREGSQELNPAKNPSYNLVISVKDMGGQSE--NSFSDTTSVDIIVTEN---IWKAP 242 Query: 274 YSASIEENCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKV 333 + EN I++ + ++ G AQY ++ F D EG + V Sbjct: 243 KPVEMVENSTDPHPIKITQVRWNDPG-----AQYSLVDKEKLPRFPFSID---QEGDIYV 294 Query: 334 VKMLDYEQAPNIQLSIGVKNQADFHYSVASQFQ----MHPTPVRIQVVDVREGPAFHPST 389 + LD E+ A Y+VA +P + ++V D+ + P PS Sbjct: 295 TQPLDREE-----------KDAYVFYAVAKDEYGKPLSYPLEIHVKVKDINDNPPTCPSP 343 Query: 390 M-AFSVREGIKGSSLLNYVLGTYTAIDLDTGNPATD-VRYIIGHDA------GSWLKIDS 441 + F V+E + L +GT TA D D N A + Y I G +L I + Sbjct: 344 VTVFEVQE----NERLGNSIGTLTAHDRDEENTANSFLNYRIVEQTPKLPMDGLFL-IQT 398 Query: 442 RTGEIQFSREFDKKSKYIINGIYTAEILAIDDGSGKTATGTICIEVPDINDYCPNIFPE- 500 G +Q +++ KK + + + D KT + I V DIND P IF + Sbjct: 399 YAGMLQLAKQSLKKQDTPQYNL----TIEVSDKDFKTLC-FVQINVIDINDQIP-IFEKS 452 Query: 501 ---RRTICIDS--PSVLISVNEHSYGSPFT 525 T+ D+ S ++++ PFT Sbjct: 453 DYGNLTLAEDTNIGSTILTIQATDADEPFT 482 >gi|90193626 cadherin 9, type 2 preproprotein [Homo sapiens] Length = 789 Score = 174 bits (442), Expect = 3e-43 Identities = 181/686 (26%), Positives = 301/686 (43%), Gaps = 65/686 (9%) Query: 44 VRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQ-KITYRISGVGIDRPPYGVFTI 102 +RR KR W+ E + + K+ +D + + Y ++G G +F I Sbjct: 48 LRRTKRGWMWNQFFLLEEYTGTDTQYVGKLHTDQDKGDGNLKYILTGDGAG----SLFVI 103 Query: 103 NPRTGEINITSVVDREITPLFLIYCRALNSR-GEDLERPLELRVKVMDINDNAPVFSQSV 161 + TG+I+ +DRE L+++ +A++ + G +E E +K+ DINDN P F++ + Sbjct: 104 DENTGDIHAAKKLDREEKSLYILRAKAIDRKTGRQVEPESEFIIKIHDINDNEPKFTKDL 163 Query: 162 YTASIEENSDANTLVVKLCATDADEENHLNS-KIAYKIVSQEPSGAPMFILNRYTGEVCT 220 YTAS+ E S T V+++ ATDAD+ N+ NS K+ Y I+ G P F ++ +G + T Sbjct: 164 YTASVPEMSGVGTSVIQVTATDADDANYGNSAKVVYSIL----QGQPYFSVDPESGIIKT 219 Query: 221 MSSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEE 280 + RE Y +V++ D G GLS I + DVN+N P +++Y + E Sbjct: 220 ALPDMSRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNNNPPRFPQSTYQFNSPE 279 Query: 281 NC-LSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDY 339 + L + L R++A D D +N +Y I G+ + FD+ TD T EGI+ V + LD+ Sbjct: 280 SVPLGTHLGRIKANDPDV--GENAEMEYSIAEGDGADMFDVITDKDTQEGIITVKQNLDF 337 Query: 340 EQAPNIQLSIGVKN-QADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGI 398 E L + N D + F+ V+I V D+ E P F + V E + Sbjct: 338 ENQMLYTLRVDASNTHPDPRFLHLGPFK-DTAVVKISVEDIDEPPVFTKVSYLIEVDEDV 396 Query: 399 KGSSLLNYVLGTYTAIDLDTGNPATDVRYIIGH--DAGSWLKIDSRTGEIQFSREFDKKS 456 K S ++G TA D D N ++Y + D I S G I + D++S Sbjct: 397 KEGS----IIGQVTAYDPDARNNL--IKYSVDRHTDMDRIFGIHSENGSIFTLKALDRES 450 Query: 457 KYIINGIYTAEILAIDDGSGKTATGTICIEVPDINDYCPNIFPERRTICIDS--PSVLIS 514 N TA + + +++ + I + DIND+ P T ++ P LI Sbjct: 451 SPWHNITVTATEI---NNPKQSSHIPVFIRILDINDHAPEFAMYYETFVCENAKPGQLIQ 507 Query: 515 V------NEHSYGSPFTFCVVDEPPGIADMWDVRSTNATSAILTAKQVLS---PGFYEIP 565 ++ G F F V E + V + + T+ I+T K S Y +P Sbjct: 508 TVSVMDKDDPPRGHKFFFEPVPEFTLNPNFTIVDNKDNTAGIMTRKDGYSRNKMSTYLLP 567 Query: 566 ILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVSN 625 IL+ D+ + + C C DN + S A +A + + Sbjct: 568 ILIFDNDYPIQSSTGTLTIRVCAC-DNQGNMQSCTA------------------EALILS 608 Query: 626 VGLGPAGIGMMVLGILLLILAPLLLLLCCCKQRQPEGLGTRFAPVPEGGEGVMQSWRIEG 685 GL + ++L +L+L++ ++L +QR+ E L V + + ++ EG Sbjct: 609 AGLSTGALVAILLCVLILLIL-VVLFAALKRQRKKEPLIISKDDVRDN----IVTYNDEG 663 Query: 686 AHPEDRDVSNICAPMTASNTQDRMDS 711 ED +I T N + R DS Sbjct: 664 GGEEDTQAFDI---GTLRNPEAREDS 686 >gi|16306530 cadherin 10, type 2 preproprotein [Homo sapiens] Length = 788 Score = 174 bits (440), Expect = 5e-43 Identities = 168/636 (26%), Positives = 280/636 (44%), Gaps = 61/636 (9%) Query: 44 VRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQ-KITYRISGVGIDRPPYGVFTI 102 + RQKR W+ E S + K+ SD + + Y +SG G +F I Sbjct: 49 LHRQKRGWMWNQFFLLEEYTGSDYQYVGKLHSDQDKGDGSLKYILSGDGAGT----LFII 104 Query: 103 NPRTGEINITSVVDREITPLFLIYCRALNSRG-EDLERPLELRVKVMDINDNAPVFSQSV 161 + +TG+I+ T +DRE + + +A+N R +E E +K+ DINDN P F + + Sbjct: 105 DEKTGDIHATRRIDREEKAFYTLRAQAINRRTLRPVEPESEFVIKIHDINDNEPTFPEEI 164 Query: 162 YTASIEENSDANTLVVKLCATDADEENHLNS-KIAYKIVSQEPSGAPMFILNRYTGEVCT 220 YTAS+ E S T VV++ ATDAD+ ++ NS ++ Y I+ G P F + TG + T Sbjct: 165 YTASVPEMSVVGTSVVQVTATDADDPSYGNSARVIYSIL----QGQPYFSVEPETGIIRT 220 Query: 221 MSSFLDREQHSMYNLVVRGSDRDGAADGLSSECDCRIKVLDVNDNFPTL-EKTSYSASIE 279 ++RE Y +V++ D G GLS I + DVNDN P + T + +E Sbjct: 221 ALPNMNRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQNTIHLRVLE 280 Query: 280 ENCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDY 339 + + + + ++A D D N +Y I+ G+ + FDI T+ T EGI+ V K LDY Sbjct: 281 SSPVGTAIGSVKATDADT--GKNAEVEYRIIDGDGTDMFDIVTEKDTQEGIITVKKPLDY 338 Query: 340 EQAPNIQLSIGVKN-QADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGI 398 E L + +N D + F+ T V+I + DV E P F S+ F V E I Sbjct: 339 ESRRLYTLKVEAENTHVDPRFYYLGPFK-DTTIVKISIEDVDEPPVFSRSSYLFEVHEDI 397 Query: 399 KGSSLLNYVLGTYTAIDLDTGNPATDVRYIIGH--DAGSWLKIDSRTGEIQFSREFDKK- 455 + + ++GT A D D + ++ +R+ + D I S G + S+ D++ Sbjct: 398 E----VGTIIGTVMARDPD--SISSPIRFSLDRHTDLDRIFNIHSGNGSLYTSKPLDREL 451 Query: 456 SKYIINGIYTAEILAIDDGSGKTATGTICIEVPDINDYCPNIFPERRTICIDS--PSVLI 513 S++ + AEI + +T + + + D+ND P T ++ P LI Sbjct: 452 SQWHNLTVIAAEI----NNPKETTRVAVFVRILDVNDNAPQFAVFYDTFVCENARPGQLI 507 Query: 514 SV------NEHSYGSPFTFCVVDEPPGIADMWDVRSTNATSAILTAKQVLSP---GFYEI 564 ++ G F F + P + + T+ ILT K + Y + Sbjct: 508 QTISAVDKDDPLGGQKFFFSLAAVNPNFTVQ---DNEDNTARILTRKNGFNRHEISTYLL 564 Query: 565 PILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVS 624 P+++ D+ + + C CD A + AG+S Sbjct: 565 PVVISDNDYPIQSSTGTLTIRVCACDSQGNMQSCSAEALLL--------------PAGLS 610 Query: 625 NVGLGPAGIGMMVLGILLLILAPLLLLLCCCKQRQP 660 L I +++ I+LL++ L L ++++P Sbjct: 611 TGAL----IAILLCIIILLVIVVLFAALKRQRKKEP 642 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.135 0.402 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 40,575,950 Number of Sequences: 37866 Number of extensions: 1926777 Number of successful extensions: 7042 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 192 Number of HSP's successfully gapped in prelim test: 21 Number of HSP's that attempted gapping in prelim test: 4150 Number of HSP's gapped (non-prelim): 902 length of query: 1040 length of database: 18,247,518 effective HSP length: 112 effective length of query: 928 effective length of database: 14,006,526 effective search space: 12998056128 effective search space used: 12998056128 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.