Guide to the Human Genome
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Search of human proteins with 29789401

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|29789401 ubiquitin-conjugating enzyme E2Q 2 isoform 1 [Homo
sapiens]
         (375 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|29789401 ubiquitin-conjugating enzyme E2Q 2 isoform 1 [Homo s...   762   0.0  
gi|223890185 ubiquitin-conjugating enzyme E2Q 2 isoform 2 [Homo ...   638   0.0  
gi|31543906 ubiquitin-conjugating enzyme E2Q [Homo sapiens]           551   e-157
gi|223555979 probable ubiquitin-conjugating enzyme E2 FLJ25076 [...   168   6e-42
gi|239756416 PREDICTED: hypothetical protein [Homo sapiens]            55   1e-07
gi|169208393 PREDICTED: hypothetical protein [Homo sapiens]            55   1e-07
gi|163660385 ubiquitin-conjugating enzyme E2K isoform 2 [Homo sa...    47   2e-05
gi|4885417 ubiquitin-conjugating enzyme E2K isoform 1 [Homo sapi...    47   4e-05
gi|60498973 myelin transcription factor 1-like [Homo sapiens]          43   5e-04
gi|19923475 tRNA methyltransferase 6 [Homo sapiens]                    42   7e-04
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]            42   9e-04
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    41   0.002
gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 famil...    40   0.004
gi|22749303 hypothetical protein LOC196477 [Homo sapiens]              40   0.004
gi|21735415 centromere protein B [Homo sapiens]                        39   0.008
gi|17975763 myelin transcription factor 1 [Homo sapiens]               39   0.008
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    39   0.008
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    39   0.008
gi|145301543 ubiquitin-conjugating enzyme E2W (putative) isoform...    39   0.008
gi|47933381 ubiquitin-conjugating enzyme E2W (putative) isoform ...    39   0.008
gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo ...    38   0.013
gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo ...    38   0.013
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]       38   0.013
gi|103471997 DNA-directed RNA polymerase I A [Homo sapiens]            38   0.013
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi...    38   0.017
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is...    38   0.017
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is...    38   0.017
gi|87298939 hypothetical protein LOC131831 [Homo sapiens]              37   0.022
gi|31543091 MAK16 homolog [Homo sapiens]                               37   0.022
gi|46276863 parathymosin [Homo sapiens]                                37   0.022

>gi|29789401 ubiquitin-conjugating enzyme E2Q 2 isoform 1 [Homo
           sapiens]
          Length = 375

 Score =  762 bits (1967), Expect = 0.0
 Identities = 375/375 (100%), Positives = 375/375 (100%)

Query: 1   MSVSGLKAELKFLASIFDKNHERFRIVSWKLDELHCQFLVPQQGSPHSLPPPLTLHCNIT 60
           MSVSGLKAELKFLASIFDKNHERFRIVSWKLDELHCQFLVPQQGSPHSLPPPLTLHCNIT
Sbjct: 1   MSVSGLKAELKFLASIFDKNHERFRIVSWKLDELHCQFLVPQQGSPHSLPPPLTLHCNIT 60

Query: 61  ESYPSSSPIWFVDSEDPNLTSVLERLEDTKNNNLLRQQLKWLICELCSLYNLPKHLDVEM 120
           ESYPSSSPIWFVDSEDPNLTSVLERLEDTKNNNLLRQQLKWLICELCSLYNLPKHLDVEM
Sbjct: 61  ESYPSSSPIWFVDSEDPNLTSVLERLEDTKNNNLLRQQLKWLICELCSLYNLPKHLDVEM 120

Query: 121 LDQPLPTGQNGTTEEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKENL 180
           LDQPLPTGQNGTTEEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKENL
Sbjct: 121 LDQPLPTGQNGTTEEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKENL 180

Query: 181 AILEKIRKTQRQDHLNGAVSGSVQASDRLMKELRDIYRSQSYKTGIYSVELINDSLYDWH 240
           AILEKIRKTQRQDHLNGAVSGSVQASDRLMKELRDIYRSQSYKTGIYSVELINDSLYDWH
Sbjct: 181 AILEKIRKTQRQDHLNGAVSGSVQASDRLMKELRDIYRSQSYKTGIYSVELINDSLYDWH 240

Query: 241 VKLQKVDPDSPLHSDLQILKEKEGIEYILLNFSFKDNFPFDPPFVRVVLPVLSGGYVLGG 300
           VKLQKVDPDSPLHSDLQILKEKEGIEYILLNFSFKDNFPFDPPFVRVVLPVLSGGYVLGG
Sbjct: 241 VKLQKVDPDSPLHSDLQILKEKEGIEYILLNFSFKDNFPFDPPFVRVVLPVLSGGYVLGG 300

Query: 301 GALCMELLTKQGWSSAYSIESVIMQINATLVKGKARVQFGANKNQYNLARAQQSYNSIVQ 360
           GALCMELLTKQGWSSAYSIESVIMQINATLVKGKARVQFGANKNQYNLARAQQSYNSIVQ
Sbjct: 301 GALCMELLTKQGWSSAYSIESVIMQINATLVKGKARVQFGANKNQYNLARAQQSYNSIVQ 360

Query: 361 IHEKNGWYTPPKEDG 375
           IHEKNGWYTPPKEDG
Sbjct: 361 IHEKNGWYTPPKEDG 375


>gi|223890185 ubiquitin-conjugating enzyme E2Q 2 isoform 2 [Homo
           sapiens]
          Length = 359

 Score =  638 bits (1646), Expect = 0.0
 Identities = 319/336 (94%), Positives = 320/336 (95%), Gaps = 10/336 (2%)

Query: 50  PPPLTLHCNITE----------SYPSSSPIWFVDSEDPNLTSVLERLEDTKNNNLLRQQL 99
           PP L   C + E          SYPSSSPIWFVDSEDPNLTSVLERLEDTKNNNLLRQQL
Sbjct: 24  PPGLAARCCVLERSIVPSLRQESYPSSSPIWFVDSEDPNLTSVLERLEDTKNNNLLRQQL 83

Query: 100 KWLICELCSLYNLPKHLDVEMLDQPLPTGQNGTTEEVTSEEEEEEEEMAEDIEDLDHYEM 159
           KWLICELCSLYNLPKHLDVEMLDQPLPTGQNGTTEEVTSEEEEEEEEMAEDIEDLDHYEM
Sbjct: 84  KWLICELCSLYNLPKHLDVEMLDQPLPTGQNGTTEEVTSEEEEEEEEMAEDIEDLDHYEM 143

Query: 160 KEEEPISGKKSEDEGIEKENLAILEKIRKTQRQDHLNGAVSGSVQASDRLMKELRDIYRS 219
           KEEEPISGKKSEDEGIEKENLAILEKIRKTQRQDHLNGAVSGSVQASDRLMKELRDIYRS
Sbjct: 144 KEEEPISGKKSEDEGIEKENLAILEKIRKTQRQDHLNGAVSGSVQASDRLMKELRDIYRS 203

Query: 220 QSYKTGIYSVELINDSLYDWHVKLQKVDPDSPLHSDLQILKEKEGIEYILLNFSFKDNFP 279
           QSYKTGIYSVELINDSLYDWHVKLQKVDPDSPLHSDLQILKEKEGIEYILLNFSFKDNFP
Sbjct: 204 QSYKTGIYSVELINDSLYDWHVKLQKVDPDSPLHSDLQILKEKEGIEYILLNFSFKDNFP 263

Query: 280 FDPPFVRVVLPVLSGGYVLGGGALCMELLTKQGWSSAYSIESVIMQINATLVKGKARVQF 339
           FDPPFVRVVLPVLSGGYVLGGGALCMELLTKQGWSSAYSIESVIMQINATLVKGKARVQF
Sbjct: 264 FDPPFVRVVLPVLSGGYVLGGGALCMELLTKQGWSSAYSIESVIMQINATLVKGKARVQF 323

Query: 340 GANKNQYNLARAQQSYNSIVQIHEKNGWYTPPKEDG 375
           GANKNQYNLARAQQSYNSIVQIHEKNGWYTPPKEDG
Sbjct: 324 GANKNQYNLARAQQSYNSIVQIHEKNGWYTPPKEDG 359


>gi|31543906 ubiquitin-conjugating enzyme E2Q [Homo sapiens]
          Length = 422

 Score =  551 bits (1419), Expect = e-157
 Identities = 286/386 (74%), Positives = 319/386 (82%), Gaps = 20/386 (5%)

Query: 6   LKAELKFLASIFDKNHERFRIVSWKLDELHCQFLVPQQGS--------PHSLPP------ 51
           L+ ELK L SIF + HERFRI S  LDEL C+FL+   G         PH LPP      
Sbjct: 41  LRRELKLLESIFHRGHERFRIASACLDELSCEFLLAGAGGAGAGAAPGPH-LPPRGSVPG 99

Query: 52  -PLTLHCNITESYPSSSPIWFVDSEDPNLTSVLERLEDTKNNN-LLRQQLKWLICELCSL 109
            P+ +HCNITESYP+  PIW V+S+DPNL +VLERL D K  N LL Q LK +I +LC L
Sbjct: 100 DPVRIHCNITESYPAVPPIWSVESDDPNLAAVLERLVDIKKGNTLLLQHLKRIISDLCKL 159

Query: 110 YNLPKHLDVEMLDQPLPTGQNGTTEEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKK 169
           YNLP+H DVEMLDQPLP  Q  T E+V+SE+E+EE  M ED EDLDHYEMKEEEP  GKK
Sbjct: 160 YNLPQHPDVEMLDQPLPAEQC-TQEDVSSEDEDEE--MPEDTEDLDHYEMKEEEPAEGKK 216

Query: 170 SEDEGIEKENLAILEKIRKTQRQDHLNGAVSGSVQASDRLMKELRDIYRSQSYKTGIYSV 229
           SED+GI KENLAILEKI+K QRQD+LNGAVSGSVQA+DRLMKELRDIYRSQS+K G Y+V
Sbjct: 217 SEDDGIGKENLAILEKIKKNQRQDYLNGAVSGSVQATDRLMKELRDIYRSQSFKGGNYAV 276

Query: 230 ELINDSLYDWHVKLQKVDPDSPLHSDLQILKEKEGIEYILLNFSFKDNFPFDPPFVRVVL 289
           EL+NDSLYDW+VKL KVD DS LH+DLQILKEKEG ++ILLNFSFKDNFPFDPPFVRVV 
Sbjct: 277 ELVNDSLYDWNVKLLKVDQDSALHNDLQILKEKEGADFILLNFSFKDNFPFDPPFVRVVS 336

Query: 290 PVLSGGYVLGGGALCMELLTKQGWSSAYSIESVIMQINATLVKGKARVQFGANKNQYNLA 349
           PVLSGGYVLGGGA+CMELLTKQGWSSAYSIESVIMQI+ATLVKGKARVQFGANK+QY+L 
Sbjct: 337 PVLSGGYVLGGGAICMELLTKQGWSSAYSIESVIMQISATLVKGKARVQFGANKSQYSLT 396

Query: 350 RAQQSYNSIVQIHEKNGWYTPPKEDG 375
           RAQQSY S+VQIHEKNGWYTPPKEDG
Sbjct: 397 RAQQSYKSLVQIHEKNGWYTPPKEDG 422


>gi|223555979 probable ubiquitin-conjugating enzyme E2 FLJ25076
           [Homo sapiens]
          Length = 161

 Score =  168 bits (426), Expect = 6e-42
 Identities = 85/168 (50%), Positives = 117/168 (69%), Gaps = 9/168 (5%)

Query: 210 MKELRDIYRSQSYKTGIYSVELINDSLYDWHVKLQKVDPDSPLHSDLQILKEKEGIEYIL 269
           MKEL+DI R         SVEL+++SL+DW+VKL +VD DS L  D++    +   E+IL
Sbjct: 1   MKELQDIARLSDR---FISVELVDESLFDWNVKLHQVDKDSVLWQDMK----ETNTEFIL 53

Query: 270 LNFSFKDNFPFDPPFVRVVLPVLSGGYVLGGGALCMELLTKQGWSSAYSIESVIMQINAT 329
           LN +F DNFPF PPF+RV+ P L  GYVL GGA+CMELLT +GWSSAY++E+V+ Q  A+
Sbjct: 54  LNLTFPDNFPFSPPFMRVLSPRLENGYVLDGGAICMELLTPRGWSSAYTVEAVMRQFAAS 113

Query: 330 LVKGKARV--QFGANKNQYNLARAQQSYNSIVQIHEKNGWYTPPKEDG 375
           LVKG+ R+  + G +K  ++   A+ ++ S+V+ HEK GW TPP  DG
Sbjct: 114 LVKGQGRICRKAGKSKKSFSRKEAEATFKSLVKTHEKYGWVTPPVSDG 161


>gi|239756416 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 97

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 26/40 (65%), Positives = 33/40 (82%)

Query: 61  ESYPSSSPIWFVDSEDPNLTSVLERLEDTKNNNLLRQQLK 100
           ES  S SPI FVDS++PNLTSVLE LEDTKNN+ ++++ K
Sbjct: 45  ESSSSFSPICFVDSDEPNLTSVLEHLEDTKNNHSVKREAK 84


>gi|169208393 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 97

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 26/40 (65%), Positives = 33/40 (82%)

Query: 61  ESYPSSSPIWFVDSEDPNLTSVLERLEDTKNNNLLRQQLK 100
           ES  S SPI FVDS++PNLTSVLE LEDTKNN+ ++++ K
Sbjct: 45  ESSSSFSPICFVDSDEPNLTSVLEHLEDTKNNHSVKREAK 84


>gi|163660385 ubiquitin-conjugating enzyme E2K isoform 2 [Homo
           sapiens]
          Length = 157

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 34/155 (21%), Positives = 75/155 (48%), Gaps = 16/155 (10%)

Query: 205 ASDRLMKELRDIYRSQSYKTGIYSVELINDSLYDWHVKLQKVDPDSPLHSDLQILKEKEG 264
           A  R+ +E +++ +S+        V+L++++  +   ++    PD+P           EG
Sbjct: 5   AVQRIKREFKEVLKSEETSKNQIKVDLVDENFTELRGEIAG-PPDTPY----------EG 53

Query: 265 IEYILLNFSFKDNFPFDPPFVRVVLPVLSGGYVLGGGALCMELLTKQGWSSAYSIESVIM 324
             Y  L     + +PF+PP VR +  +         GA+C+++L K  W++A ++ +V++
Sbjct: 54  GRY-QLEIKIPETYPFNPPKVRFITKIWHPNISSVTGAICLDIL-KDQWAAAMTLRTVLL 111

Query: 325 QINATLVKGK---ARVQFGANKNQYNLARAQQSYN 356
            + A L   +    +    AN+N   +A + +S++
Sbjct: 112 SLQALLAAAEPDDPQDAVVANQNAVIVALSSKSWD 146


>gi|4885417 ubiquitin-conjugating enzyme E2K isoform 1 [Homo
           sapiens]
          Length = 200

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 29/126 (23%), Positives = 62/126 (49%), Gaps = 13/126 (10%)

Query: 205 ASDRLMKELRDIYRSQSYKTGIYSVELINDSLYDWHVKLQKVDPDSPLHSDLQILKEKEG 264
           A  R+ +E +++ +S+        V+L++++  +   ++    PD+P           EG
Sbjct: 5   AVQRIKREFKEVLKSEETSKNQIKVDLVDENFTELRGEIAG-PPDTPY----------EG 53

Query: 265 IEYILLNFSFKDNFPFDPPFVRVVLPVLSGGYVLGGGALCMELLTKQGWSSAYSIESVIM 324
             Y  L     + +PF+PP VR +  +         GA+C+++L K  W++A ++ +V++
Sbjct: 54  GRY-QLEIKIPETYPFNPPKVRFITKIWHPNISSVTGAICLDIL-KDQWAAAMTLRTVLL 111

Query: 325 QINATL 330
            + A L
Sbjct: 112 SLQALL 117


>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
          Length = 1184

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 36/139 (25%), Positives = 64/139 (46%), Gaps = 5/139 (3%)

Query: 134 EEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKENLAILEKIRKTQRQD 193
           EE   EE+E+++E  ED+ED +  E +EEE    +++ED  +   N  I++    T++ D
Sbjct: 132 EEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQMNCHNTRIMQ---DTEKDD 188

Query: 194 HLNGAVSGSVQASDRLMKELRDIYRSQSYKTGIYSVELIN--DSLYDWHVKLQKVDPDSP 251
           + N       +   + +  L  I    +Y+    S    N  +SL D   K + +   S 
Sbjct: 189 NNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESEMNSNTSNSLEDDSDKNENLGRKSE 248

Query: 252 LHSDLQILKEKEGIEYILL 270
           L  DL     +E ++ + L
Sbjct: 249 LSLDLDSDVVRETVDSLKL 267



 Score = 33.5 bits (75), Expect = 0.32
 Identities = 17/47 (36%), Positives = 31/47 (65%), Gaps = 3/47 (6%)

Query: 133 TEEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKEN 179
           TE++  +EE+E EE +ED ++    + ++EE   G + E+E IE+E+
Sbjct: 96  TEDMDEKEEDEGEEYSEDNDEPGDEDEEDEE---GDREEEEEIEEED 139


>gi|19923475 tRNA methyltransferase 6 [Homo sapiens]
          Length = 497

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 52/200 (26%), Positives = 86/200 (43%), Gaps = 13/200 (6%)

Query: 114 KHLDVEMLDQPLPTGQNGTTEEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPIS----GKK 169
           K L  E  D  L    NGT EE  + E+E E+ MAE  E     + +  E IS     K 
Sbjct: 273 KMLSSEPKDSALVEESNGTLEEKQASEQENEDSMAEAPESNHPEDQETMETISQDPEHKG 332

Query: 170 SEDEGIEKENLAILEKIRKTQRQDHLNGAVSGSVQASDRLMKELRDIYRSQSYKTGIYSV 229
            ++ G +K+ +   ++ ++ QR+ HL  A   S + +D L      I  S+ + T +   
Sbjct: 333 PKERGSKKDYIQEKQRRQEEQRKRHLEAAALLSERNADGL------IVASRFHPTPLLLS 386

Query: 230 ELINDSLYDWHVKLQKVDPDSPLHSDLQILKEKEGIEYILLNFSFKDNFPFDPPFVRVVL 289
            L  D +      +       PL      L+E+ G+  + L+ ++  N+   P      L
Sbjct: 387 LL--DFVAPSRPFVVYCQYKEPLLECYTKLRERGGVINLRLSETWLRNYQVLPDRSHPKL 444

Query: 290 PVL-SGGYVLGGGALCMELL 308
            +   GGY+L G  + M+ L
Sbjct: 445 LMSGGGGYLLSGFTVAMDNL 464


>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 185

 Score = 42.0 bits (97), Expect = 9e-04
 Identities = 31/73 (42%), Positives = 41/73 (56%), Gaps = 8/73 (10%)

Query: 123 QPLPTGQNGTTEEVTS-EEEEEEEEMAEDIEDLDHYEMKEE----EPISGKKSEDEGIEK 177
           Q LP  +    EE    EEEE+EEE  ED E+ +  E KEE    E   GKK E+E +E+
Sbjct: 114 QGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEE 173

Query: 178 ENLAILEKIRKTQ 190
           E   I  +I++TQ
Sbjct: 174 E---IDTEIQRTQ 183



 Score = 32.7 bits (73), Expect = 0.55
 Identities = 19/55 (34%), Positives = 32/55 (58%)

Query: 139 EEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKENLAILEKIRKTQRQD 193
           E EEEEEE+ E+ ++ +  E +EEE    +K EDE  E++    +E+ +  +  D
Sbjct: 122 EVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEID 176



 Score = 30.8 bits (68), Expect = 2.1
 Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 4/71 (5%)

Query: 139 EEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKENLAILEKIRKTQRQDHLNGA 198
           EEEE EEE  E++E+ +  E KEE+    +K E++  ++E     EK  K   ++ +   
Sbjct: 119 EEEEVEEE-EEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEE---EEKEGKKMEEEKVEEE 174

Query: 199 VSGSVQASDRL 209
           +   +Q +  L
Sbjct: 175 IDTEIQRTQYL 185


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 21/45 (46%), Positives = 27/45 (60%)

Query: 134 EEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKE 178
           EE   EEEEEEEE  E+ ED +  E  EEE    ++ E+E  E+E
Sbjct: 890 EEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEE 934



 Score = 36.6 bits (83), Expect = 0.038
 Identities = 22/49 (44%), Positives = 30/49 (61%), Gaps = 4/49 (8%)

Query: 134 EEVTSEEEEEEEEMAEDIEDLDHY---EMKEEEPISGKKSEDEG-IEKE 178
           EE   EEEEEEE+  E+ ED + Y   E +EEE    +  E+EG +E+E
Sbjct: 897 EEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEE 945



 Score = 34.3 bits (77), Expect = 0.19
 Identities = 20/47 (42%), Positives = 29/47 (61%)

Query: 134 EEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKENL 180
           EE   EEEEEEEE  E+  + +  E++EEE    ++ E+E  E E+L
Sbjct: 917 EEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDL 963



 Score = 33.1 bits (74), Expect = 0.42
 Identities = 14/27 (51%), Positives = 19/27 (70%)

Query: 129 QNGTTEEVTSEEEEEEEEMAEDIEDLD 155
           + G  EE   EE+EEEEE  E++EDL+
Sbjct: 938 EEGELEEEEEEEDEEEEEELEEVEDLE 964



 Score = 32.7 bits (73), Expect = 0.55
 Identities = 21/71 (29%), Positives = 36/71 (50%), Gaps = 5/71 (7%)

Query: 134 EEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKENLAILEKIRKTQRQD 193
           E+   EEE+EEE   E+ E+ + +E + EE     + E+E  ++E    LE++     +D
Sbjct: 908 EDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEV-----ED 962

Query: 194 HLNGAVSGSVQ 204
              G   G V+
Sbjct: 963 LEFGTAGGEVE 973


>gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member A [Homo sapiens]
          Length = 249

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 19/46 (41%), Positives = 28/46 (60%)

Query: 128 GQNGTTEEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDE 173
           G +   E+   EE +E+ ++ ED ED D  E  EEE +SG++ EDE
Sbjct: 166 GLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDVSGEEEEDE 211



 Score = 32.0 bits (71), Expect = 0.93
 Identities = 19/63 (30%), Positives = 36/63 (57%), Gaps = 1/63 (1%)

Query: 135 EVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKENLAILEKIRKTQRQDH 194
           +V  +EE+E+EE   + ED+   E ++EE  +  + +DE  ++E L   E+ +K +R+  
Sbjct: 184 QVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEE-DEEELGEEERGQKRKREPE 242

Query: 195 LNG 197
             G
Sbjct: 243 DEG 245



 Score = 29.6 bits (65), Expect = 4.6
 Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 2/47 (4%)

Query: 129 QNGTTEEVTSEEEEEEE--EMAEDIEDLDHYEMKEEEPISGKKSEDE 173
           + G  E+V+ EEEE+EE     E  ++ D  E+ EEE    +K E E
Sbjct: 196 EEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGEEERGQKRKREPE 242


>gi|22749303 hypothetical protein LOC196477 [Homo sapiens]
          Length = 406

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 24/68 (35%), Positives = 38/68 (55%), Gaps = 2/68 (2%)

Query: 114 KHLDVEMLDQPLPTGQNGTTEE--VTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSE 171
           K+ D E  DQ +   +  + EE  V  EEEE E+E  E++E+ ++ E  EEE    +  E
Sbjct: 283 KNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEAEYVEEGEEELEEEELEE 342

Query: 172 DEGIEKEN 179
           +E + +EN
Sbjct: 343 EEEVLEEN 350



 Score = 32.3 bits (72), Expect = 0.71
 Identities = 21/64 (32%), Positives = 39/64 (60%), Gaps = 4/64 (6%)

Query: 134 EEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPI--SGKKSEDEGIEKENLAILEKIRKTQR 191
           +E + EEEE E+E  E++ED +  E++E E +    ++ E+E +E+E   +LE+  +   
Sbjct: 298 KEASEEEEEVEDE-EEEVEDEEEEEVEEAEYVEEGEEELEEEELEEEE-EVLEENEQRGE 355

Query: 192 QDHL 195
           + HL
Sbjct: 356 EFHL 359


>gi|21735415 centromere protein B [Homo sapiens]
          Length = 599

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 26/62 (41%), Positives = 36/62 (58%), Gaps = 4/62 (6%)

Query: 128 GQNGT-TEEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKENLAILEKI 186
           G N T T  + SE EEEEEE  E+ E+    E +EEE   G++ E+EG E E L   E++
Sbjct: 392 GPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEE---GEEEEEEGGEGEELGEEEEV 448

Query: 187 RK 188
            +
Sbjct: 449 EE 450



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 22/55 (40%), Positives = 27/55 (49%)

Query: 124 PLPTGQNGTTEEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKE 178
           P  T       E   EEEEEEEE  E+ E  +  E  EEE   G + E+ G E+E
Sbjct: 393 PNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEE 447



 Score = 32.3 bits (72), Expect = 0.71
 Identities = 21/46 (45%), Positives = 29/46 (63%), Gaps = 2/46 (4%)

Query: 134 EEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKK-SEDEGIEKE 178
           EE   EEEEEEEE  E  E+ +  E +EEE   G++  E+E +E+E
Sbjct: 407 EEEEEEEEEEEEE-GEGEEEEEEGEEEEEEGGEGEELGEEEEVEEE 451



 Score = 32.3 bits (72), Expect = 0.71
 Identities = 23/60 (38%), Positives = 31/60 (51%), Gaps = 13/60 (21%)

Query: 131 GTTEEVTSEEEEE---------EEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKENLA 181
           G  EE   EEEEE         EEE  E+  D+D  E +EE+    ++S  EG+E E+ A
Sbjct: 422 GEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEED----EESSSEGLEAEDWA 477



 Score = 32.0 bits (71), Expect = 0.93
 Identities = 18/51 (35%), Positives = 26/51 (50%)

Query: 129 QNGTTEEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKEN 179
           + G  EE   E EEEEEE  E  E  +  E++EE  +   + E+E  E  +
Sbjct: 418 EEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEEEGDVDSDEEEEEDEESSS 468



 Score = 30.8 bits (68), Expect = 2.1
 Identities = 15/37 (40%), Positives = 22/37 (59%)

Query: 129 QNGTTEEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPI 165
           + G   +  SEEE++EEE  ED +D D  E  +E P+
Sbjct: 505 EGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPV 541


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 21/45 (46%), Positives = 28/45 (62%)

Query: 134 EEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKE 178
           EE   EEEEEEEE  ED E+ +  E +EEE    ++ E+E  E+E
Sbjct: 258 EEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEE 302



 Score = 37.7 bits (86), Expect = 0.017
 Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 7/88 (7%)

Query: 134 EEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKENLAILEKI------- 186
           E+   EEEEEEEE  E+ E+ +  E +EEE    ++ E+E  E+E  A  + I       
Sbjct: 260 EDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSH 319

Query: 187 RKTQRQDHLNGAVSGSVQASDRLMKELR 214
              Q+   L G  S S +    ++ E+R
Sbjct: 320 TSAQKAPELRGPESPSPKPEYSVIVEVR 347



 Score = 35.8 bits (81), Expect = 0.064
 Identities = 19/46 (41%), Positives = 28/46 (60%)

Query: 133 TEEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKE 178
           + E   EEEEEEEE  E+ E+ +  E +EEE    ++ E+E  E+E
Sbjct: 256 SHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEE 301



 Score = 35.8 bits (81), Expect = 0.064
 Identities = 19/45 (42%), Positives = 28/45 (62%)

Query: 134 EEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKE 178
           EE   EEEEEEEE  ++ E+ +  E +EEE    ++ E+E  E+E
Sbjct: 259 EEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 303



 Score = 35.4 bits (80), Expect = 0.084
 Identities = 18/43 (41%), Positives = 28/43 (65%)

Query: 136 VTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKE 178
           ++ EEE+EEEE  E+ E+ D  E +EEE    ++ E+E  E+E
Sbjct: 255 LSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 297



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 18/50 (36%), Positives = 28/50 (56%)

Query: 129 QNGTTEEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKE 178
           Q G       +EEEEEEE  E+ ++ +  E +EEE    ++ E+E  E+E
Sbjct: 251 QKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEE 300



 Score = 30.8 bits (68), Expect = 2.1
 Identities = 21/59 (35%), Positives = 29/59 (49%), Gaps = 14/59 (23%)

Query: 134 EEVTSEE--------------EEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKE 178
           E+  SEE              EEEEEE  E+ ED +  E +EEE    ++ E+E  E+E
Sbjct: 241 EDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEE 299


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 26/102 (25%), Positives = 45/102 (44%), Gaps = 8/102 (7%)

Query: 129  QNGTTEEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKENLAILEKIRK 188
            Q  ++ E  S  EEEEEE  E+ E+ +  E +EE+     KS  +G         +KIRK
Sbjct: 1393 QEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKG--------RKKIRK 1444

Query: 189  TQRQDHLNGAVSGSVQASDRLMKELRDIYRSQSYKTGIYSVE 230
              + D L      +++  +   K + +  R +     +  +E
Sbjct: 1445 ILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIE 1486



 Score = 29.3 bits (64), Expect = 6.0
 Identities = 36/164 (21%), Positives = 69/164 (42%), Gaps = 23/164 (14%)

Query: 87  EDTKNNNLLRQQLKWLICELCSLYNLPKHLDVEMLDQPLPTGQNGTTEEVTSEEEEEEEE 146
           E++ N +L+  ++  L+ E   L   P+        +  P  +   T  VTS  +EE  E
Sbjct: 594 ENSDNEHLVENEVS-LLLEESDLRRSPRV-------KTTPLRRPTETNPVTSNSDEECNE 645

Query: 147 MAEDIEDLDHYEMKEEEPISGKKSEDEGIEKENLAILEKIRKTQRQDHLNGAVSGSVQAS 206
             ++ + L     K+++    + S D  I+      L K ++++  D  +         S
Sbjct: 646 TVKEKQKLSVPVRKKDK----RNSSDSAIDNPKPNKLPKSKQSETVDQNSD--------S 693

Query: 207 DRLMKELRDIYR---SQSYKTGIYSVELINDSLYDWHVKLQKVD 247
           D ++  L+++ R   S S  T I  +   + +LYD   +  K D
Sbjct: 694 DEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDD 737


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 26/102 (25%), Positives = 45/102 (44%), Gaps = 8/102 (7%)

Query: 129  QNGTTEEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKENLAILEKIRK 188
            Q  ++ E  S  EEEEEE  E+ E+ +  E +EE+     KS  +G         +KIRK
Sbjct: 1431 QEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKG--------RKKIRK 1482

Query: 189  TQRQDHLNGAVSGSVQASDRLMKELRDIYRSQSYKTGIYSVE 230
              + D L      +++  +   K + +  R +     +  +E
Sbjct: 1483 ILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIE 1524



 Score = 29.3 bits (64), Expect = 6.0
 Identities = 36/164 (21%), Positives = 69/164 (42%), Gaps = 23/164 (14%)

Query: 87  EDTKNNNLLRQQLKWLICELCSLYNLPKHLDVEMLDQPLPTGQNGTTEEVTSEEEEEEEE 146
           E++ N +L+  ++  L+ E   L   P+        +  P  +   T  VTS  +EE  E
Sbjct: 632 ENSDNEHLVENEVS-LLLEESDLRRSPRV-------KTTPLRRPTETNPVTSNSDEECNE 683

Query: 147 MAEDIEDLDHYEMKEEEPISGKKSEDEGIEKENLAILEKIRKTQRQDHLNGAVSGSVQAS 206
             ++ + L     K+++    + S D  I+      L K ++++  D  +         S
Sbjct: 684 TVKEKQKLSVPVRKKDK----RNSSDSAIDNPKPNKLPKSKQSETVDQNSD--------S 731

Query: 207 DRLMKELRDIYR---SQSYKTGIYSVELINDSLYDWHVKLQKVD 247
           D ++  L+++ R   S S  T I  +   + +LYD   +  K D
Sbjct: 732 DEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDD 775


>gi|145301543 ubiquitin-conjugating enzyme E2W (putative) isoform 2
           [Homo sapiens]
          Length = 151

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 27/77 (35%), Positives = 41/77 (53%), Gaps = 7/77 (9%)

Query: 263 EGIEYILLNFSFKDNFPFDPP---FVRVVLPVLSGGYVLGGGALCMELLTKQGWSSAYSI 319
           EG ++ LL F F   +PFD P   F    +PV    +V   G +C+ +LT + WS A S+
Sbjct: 50  EGEKFQLL-FKFSSRYPFDSPQVMFTGENIPV--HPHVYSNGHICLSILT-EDWSPALSV 105

Query: 320 ESVIMQINATLVKGKAR 336
           +SV + I + L   K +
Sbjct: 106 QSVCLSIISMLSSCKEK 122


>gi|47933381 ubiquitin-conjugating enzyme E2W (putative) isoform 1
           [Homo sapiens]
          Length = 162

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 27/77 (35%), Positives = 41/77 (53%), Gaps = 7/77 (9%)

Query: 263 EGIEYILLNFSFKDNFPFDPP---FVRVVLPVLSGGYVLGGGALCMELLTKQGWSSAYSI 319
           EG ++ LL F F   +PFD P   F    +PV    +V   G +C+ +LT + WS A S+
Sbjct: 61  EGEKFQLL-FKFSSRYPFDSPQVMFTGENIPV--HPHVYSNGHICLSILT-EDWSPALSV 116

Query: 320 ESVIMQINATLVKGKAR 336
           +SV + I + L   K +
Sbjct: 117 QSVCLSIISMLSSCKEK 133


>gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo
            sapiens]
          Length = 5033

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 23/51 (45%), Positives = 33/51 (64%), Gaps = 1/51 (1%)

Query: 135  EVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKENLAILEK 185
            EV +EEEEEE+E  E+ E+ D  E +E+E  + ++ EDE  E+E  A  EK
Sbjct: 1869 EVFTEEEEEEDE-EEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEK 1918



 Score = 33.5 bits (75), Expect = 0.32
 Identities = 21/64 (32%), Positives = 36/64 (56%), Gaps = 6/64 (9%)

Query: 118  VEMLDQPLPTGQNGTTEEVTSEEEEEEEEMAEDIEDL----DHYEMKEEEPISGKKSEDE 173
            ++M++  + T +    +E    EEE+EEE  ED E+     +  E +EEE   G+K  +E
Sbjct: 1863 LKMIEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEK--EE 1920

Query: 174  GIEK 177
            G+E+
Sbjct: 1921 GLEE 1924


>gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo
            sapiens]
          Length = 5038

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 23/51 (45%), Positives = 33/51 (64%), Gaps = 1/51 (1%)

Query: 135  EVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKENLAILEK 185
            EV +EEEEEE+E  E+ E+ D  E +E+E  + ++ EDE  E+E  A  EK
Sbjct: 1869 EVFTEEEEEEDE-EEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEK 1918



 Score = 33.5 bits (75), Expect = 0.32
 Identities = 21/64 (32%), Positives = 36/64 (56%), Gaps = 6/64 (9%)

Query: 118  VEMLDQPLPTGQNGTTEEVTSEEEEEEEEMAEDIEDL----DHYEMKEEEPISGKKSEDE 173
            ++M++  + T +    +E    EEE+EEE  ED E+     +  E +EEE   G+K  +E
Sbjct: 1863 LKMIEPEVFTEEEEEEDEEEEGEEEDEEEKEEDEEETAQEKEDEEKEEEEAAEGEK--EE 1920

Query: 174  GIEK 177
            G+E+
Sbjct: 1921 GLEE 1924


>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
          Length = 4374

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 1/70 (1%)

Query: 127  TGQNGTTEEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSE-DEGIEKENLAILEK 185
            +G N   ++   EEEEEEE+  +D ED +  E  E++   G + E DE     N + L +
Sbjct: 2422 SGSNEDEDDSQDEEEEEEEDEEDDQEDDEGEEGDEDDDDDGSEMELDEDYPDMNASPLVR 2481

Query: 186  IRKTQRQDHL 195
              +  R+D L
Sbjct: 2482 FERFDREDDL 2491



 Score = 33.1 bits (74), Expect = 0.42
 Identities = 30/107 (28%), Positives = 48/107 (44%), Gaps = 10/107 (9%)

Query: 65  SSSPIWFVDSEDPNLTSVLERLEDTKNNNLLRQQLKWLICELCSLYNLPKHL----DVEM 120
           SS P+    S   +    L R + T   +     +K L+ E+C+L   PK++     ++ 
Sbjct: 648 SSDPLGDTASNLGSAVDELMRHQPTLKTDATTAIIK-LLEEICNLGRDPKYICQKPSIQK 706

Query: 121 LDQPL---PTGQNGTTEEVTSEEEEEEEEMAEDIEDLDHYEMKEEEP 164
            D      P   N   EE +SE+EEEEE  A  ++  +  +  E EP
Sbjct: 707 ADGTATAPPPRSNHAAEEASSEDEEEEEVQA--MQSFNSTQQNETEP 751


>gi|103471997 DNA-directed RNA polymerase I A [Homo sapiens]
          Length = 1720

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 27/75 (36%), Positives = 39/75 (52%), Gaps = 11/75 (14%)

Query: 129  QNGTTEE---VTSEEEEEEEEMAEDI-------EDLDHYEMKEEEPISGKKSEDEGIEKE 178
            Q G  EE   +   E EE +  A D        E++D YE +EEE   G++++DE +++E
Sbjct: 1390 QEGDEEEEGHIVDAEAEEGDADASDAKRKEKQEEEVD-YESEEEEEREGEENDDEDMQEE 1448

Query: 179  NLAILEKIRKTQRQD 193
                 E  RKTQ QD
Sbjct: 1449 RNPHREGARKTQEQD 1463



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 25/92 (27%), Positives = 44/92 (47%), Gaps = 13/92 (14%)

Query: 134  EEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDE------GIEKENL--AILEK 185
            EEV  E EEEEE   E+ +D D  E +       +K++++      G E++    A+L +
Sbjct: 1423 EEVDYESEEEEEREGEENDDEDMQEERNPHREGARKTQEQDEEVGLGTEEDPSLPALLTQ 1482

Query: 186  IRKTQRQDHLNGAVSGSVQASDRLMKELRDIY 217
             RK        G      +A +R ++ +R+I+
Sbjct: 1483 PRKPTHSQEPQGP-----EAMERRVQAVREIH 1509


>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 436

 Score = 37.7 bits (86), Expect = 0.017
 Identities = 28/104 (26%), Positives = 48/104 (46%), Gaps = 4/104 (3%)

Query: 119 EMLDQPLPTGQNGTTEEVTSEEEEEEEEMAEDIEDLDHYE--MKEEEPISGKKSEDEGIE 176
           +ML Q   T Q   T E   +  E+EE+M E  E +   E  M+E+E   GK+ E    +
Sbjct: 277 QMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQ 336

Query: 177 KENLAILEKIRKTQRQDHLNGAVSGSVQASDRLMKELRDIYRSQ 220
           KE +   E+  +  +Q+   G     +Q  +  +++  +  R Q
Sbjct: 337 KEQM--WEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQ 378



 Score = 32.7 bits (73), Expect = 0.55
 Identities = 17/65 (26%), Positives = 35/65 (53%)

Query: 128 GQNGTTEEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKENLAILEKIR 187
           GQ G  EE   E+EE+ ++  E + + +    K+EE +  ++ + +  E++     E++R
Sbjct: 199 GQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMR 258

Query: 188 KTQRQ 192
           K + Q
Sbjct: 259 KQEEQ 263



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 23/130 (17%), Positives = 57/130 (43%), Gaps = 4/130 (3%)

Query: 134 EEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKENLAILEKIRKTQRQD 193
           EE   E+EE+ ++  E ++  +    K+EE +   + ++E + ++   +L++  +T+ Q+
Sbjct: 233 EEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQM---REQEEQMREQEEQMLKQKEQTE-QE 288

Query: 194 HLNGAVSGSVQASDRLMKELRDIYRSQSYKTGIYSVELINDSLYDWHVKLQKVDPDSPLH 253
              G     ++  +  M+E  +  R Q  +      ++       W  K Q  +    + 
Sbjct: 289 EQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMW 348

Query: 254 SDLQILKEKE 263
              + + E+E
Sbjct: 349 KQEEQMGEQE 358



 Score = 30.0 bits (66), Expect = 3.5
 Identities = 24/98 (24%), Positives = 43/98 (43%), Gaps = 4/98 (4%)

Query: 129 QNGTTEEVTSEEEEEEEEMAEDIEDLDHYE--MKEEEPISGKKSEDEGIEKENLAILEKI 186
           Q G   E   +  E+EE+M E  E +   E  M E+E    K+ E  G ++E +   E+ 
Sbjct: 190 QEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEE- 248

Query: 187 RKTQRQDHLNGAVSGSVQASDRLMKELRDIYRSQSYKT 224
            + Q+Q+         ++  +  M+E  +    Q  +T
Sbjct: 249 -QVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT 285



 Score = 28.9 bits (63), Expect = 7.9
 Identities = 18/92 (19%), Positives = 39/92 (42%)

Query: 129 QNGTTEEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKENLAILEKIRK 188
           Q G   E   +  E+E +M E  E +   E + ++       ++E + K+   + E+  +
Sbjct: 183 QEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQ 242

Query: 189 TQRQDHLNGAVSGSVQASDRLMKELRDIYRSQ 220
            Q+Q+         ++  +  M+E  +  R Q
Sbjct: 243 VQKQEEQVQKQEEQMRKQEEQMREQEEQMREQ 274



 Score = 28.9 bits (63), Expect = 7.9
 Identities = 20/70 (28%), Positives = 36/70 (51%), Gaps = 6/70 (8%)

Query: 129 QNGTTEEVTSEEEEE----EEEMAEDIEDLDHYE--MKEEEPISGKKSEDEGIEKENLAI 182
           Q G  EE   ++EE+    EE+M +  E +   E  M+++E   G++ E  G +KE +  
Sbjct: 353 QMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMRE 412

Query: 183 LEKIRKTQRQ 192
            E+    Q++
Sbjct: 413 QEEQMGEQKE 422


>gi|156142199 euchromatic histone-lysine N-methyltransferase 2
           isoform b [Homo sapiens]
          Length = 1176

 Score = 37.7 bits (86), Expect = 0.017
 Identities = 22/56 (39%), Positives = 33/56 (58%), Gaps = 1/56 (1%)

Query: 119 EMLDQPLPTGQNGTTEEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEG 174
           E +D    +     TE++ SEEEEEEEE  E+ E+ +  E +EE+  SG +S+  G
Sbjct: 281 ERVDSDSKSEVEALTEQL-SEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSG 335



 Score = 32.7 bits (73), Expect = 0.55
 Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 2/76 (2%)

Query: 117 DVEMLDQPLPTGQNGTTEEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIE 176
           +VE L + L   +    EE   EEEEEEEE  E+ ED +     +    SG++   +   
Sbjct: 290 EVEALTEQL--SEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAKKKWR 347

Query: 177 KENLAILEKIRKTQRQ 192
           K++  +    ++ +R+
Sbjct: 348 KDSPWVKPSRKRRKRE 363


>gi|156142197 euchromatic histone-lysine N-methyltransferase 2
           isoform a [Homo sapiens]
          Length = 1210

 Score = 37.7 bits (86), Expect = 0.017
 Identities = 22/56 (39%), Positives = 33/56 (58%), Gaps = 1/56 (1%)

Query: 119 EMLDQPLPTGQNGTTEEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEG 174
           E +D    +     TE++ SEEEEEEEE  E+ E+ +  E +EE+  SG +S+  G
Sbjct: 281 ERVDSDSKSEVEALTEQL-SEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSG 335



 Score = 32.7 bits (73), Expect = 0.55
 Identities = 21/76 (27%), Positives = 37/76 (48%), Gaps = 2/76 (2%)

Query: 117 DVEMLDQPLPTGQNGTTEEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIE 176
           +VE L + L   +    EE   EEEEEEEE  E+ ED +     +    SG++   +   
Sbjct: 290 EVEALTEQL--SEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAKKKWR 347

Query: 177 KENLAILEKIRKTQRQ 192
           K++  +    ++ +R+
Sbjct: 348 KDSPWVKPSRKRRKRE 363


>gi|87298939 hypothetical protein LOC131831 [Homo sapiens]
          Length = 663

 Score = 37.4 bits (85), Expect = 0.022
 Identities = 21/58 (36%), Positives = 34/58 (58%), Gaps = 2/58 (3%)

Query: 121 LDQPLPTGQNGTTEEVTSEEEEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKE 178
           L  P   G  G  ++  SEEE EEEE  E++E+ +    +EEE +  ++ E+E +E+E
Sbjct: 4   LRSPSGFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEV--EEEEEEVVEEE 59



 Score = 30.4 bits (67), Expect = 2.7
 Identities = 19/51 (37%), Positives = 29/51 (56%), Gaps = 1/51 (1%)

Query: 129 QNGTTEEVTSEEEEEE-EEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKE 178
           Q  + EE+  EEEEEE EE  E++E+ +    +EEE +  ++   E  E E
Sbjct: 18  QKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELE 68


>gi|31543091 MAK16 homolog [Homo sapiens]
          Length = 300

 Score = 37.4 bits (85), Expect = 0.022
 Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 14/83 (16%)

Query: 109 LYNLPKHLDVEMLDQPLPTGQNGTTEEVTSEEEEEEE----EMAED----------IEDL 154
           +YN P H   + L+Q      +  TEE   ++++EE+    E  ED           ED+
Sbjct: 178 IYNFPIHAFDKALEQQEAESDSSDTEEKDDDDDDEEDVGKREFVEDGEVDESDISDFEDM 237

Query: 155 DHYEMKEEEPISGKKSEDEGIEK 177
           D  +   +E   GK S +E  EK
Sbjct: 238 DKLDASSDEDQDGKSSSEEEEEK 260


>gi|46276863 parathymosin [Homo sapiens]
          Length = 102

 Score = 37.4 bits (85), Expect = 0.022
 Identities = 28/69 (40%), Positives = 37/69 (53%), Gaps = 7/69 (10%)

Query: 134 EEVTSEE----EEEEEEMAEDIEDLDHYEMKEEEPISGKKSEDEGIEKENLAILEKIRKT 189
           +EV  EE    EEEEEE AED E+ D  E ++EE    ++ +DEG   +  A  E     
Sbjct: 35  KEVVEEEENGAEEEEEETAEDGEEEDEGEEEDEEE---EEEDDEGPALKRAAEEEDEADP 91

Query: 190 QRQDHLNGA 198
           +RQ   NGA
Sbjct: 92  KRQKTENGA 100


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.133    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,962,684
Number of Sequences: 37866
Number of extensions: 822683
Number of successful extensions: 10031
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 230
Number of HSP's successfully gapped in prelim test: 278
Number of HSP's that attempted gapping in prelim test: 5745
Number of HSP's gapped (non-prelim): 2495
length of query: 375
length of database: 18,247,518
effective HSP length: 104
effective length of query: 271
effective length of database: 14,309,454
effective search space: 3877862034
effective search space used: 3877862034
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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