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Search of human proteins with 28558990
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28558990 thyroid peroxidase isoform e [Homo sapiens]
(760 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28558990 thyroid peroxidase isoform e [Homo sapiens] 1582 0.0
gi|28558982 thyroid peroxidase isoform a [Homo sapiens] 1025 0.0
gi|28558988 thyroid peroxidase isoform d [Homo sapiens] 904 0.0
gi|28558984 thyroid peroxidase isoform b [Homo sapiens] 885 0.0
gi|4557759 myeloperoxidase [Homo sapiens] 292 9e-79
gi|4503595 eosinophil peroxidase [Homo sapiens] 292 9e-79
gi|231569458 lactoperoxidase isoform 3 preproprotein [Homo sapiens] 291 2e-78
gi|40549418 lactoperoxidase isoform 1 preproprotein [Homo sapiens] 291 2e-78
gi|109150416 peroxidasin [Homo sapiens] 256 4e-68
gi|126517478 peroxidasin homolog-like [Homo sapiens] 224 2e-58
gi|148886654 polydom [Homo sapiens] 72 1e-12
gi|20149640 dual oxidase 1 precursor [Homo sapiens] 67 8e-11
gi|28872751 dual oxidase 1 precursor [Homo sapiens] 67 8e-11
gi|132566532 dual oxidase 2 precursor [Homo sapiens] 65 2e-10
gi|194328809 latent transforming growth factor beta binding prot... 64 4e-10
gi|18497288 latent transforming growth factor beta binding prote... 64 4e-10
gi|24430141 fibrillin 1 precursor [Homo sapiens] 55 3e-07
gi|66346695 fibrillin 2 precursor [Homo sapiens] 52 2e-06
gi|56237021 fibrillin 3 precursor [Homo sapiens] 52 2e-06
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 52 2e-06
gi|157384998 low density lipoprotein receptor-related protein 4 ... 51 3e-06
gi|122937283 6720455I24Rik homolog [Homo sapiens] 51 3e-06
gi|110347437 latent transforming growth factor beta binding prot... 51 5e-06
gi|110347412 latent transforming growth factor beta binding prot... 51 5e-06
gi|110347431 latent transforming growth factor beta binding prot... 51 5e-06
gi|46249414 latent transforming growth factor beta binding prote... 50 6e-06
gi|46249412 latent transforming growth factor beta binding prote... 50 6e-06
gi|4557733 latent transforming growth factor beta binding protei... 48 3e-05
gi|190343004 EGF-containing fibulin-like extracellular matrix pr... 48 3e-05
gi|118572606 hemicentin 1 [Homo sapiens] 48 4e-05
>gi|28558990 thyroid peroxidase isoform e [Homo sapiens]
Length = 760
Score = 1582 bits (4097), Expect = 0.0
Identities = 760/760 (100%), Positives = 760/760 (100%)
Query: 1 MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR 60
MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR
Sbjct: 1 MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR 60
Query: 61 NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS 120
NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS
Sbjct: 61 NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS 120
Query: 121 EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV 180
EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV
Sbjct: 121 EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV 180
Query: 181 YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD 240
YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD
Sbjct: 181 YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD 240
Query: 241 IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQIITLRDYIPRILGPEAFQQYVGPYEGY 300
IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQIITLRDYIPRILGPEAFQQYVGPYEGY
Sbjct: 241 IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQIITLRDYIPRILGPEAFQQYVGPYEGY 300
Query: 301 DSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGLWLHQAFFSPWTLLRGG 360
DSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGLWLHQAFFSPWTLLRGG
Sbjct: 301 DSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGLWLHQAFFSPWTLLRGG 360
Query: 361 GLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDLASINLQRGRDHGLPGYNE 420
GLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDLASINLQRGRDHGLPGYNE
Sbjct: 361 GLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDLASINLQRGRDHGLPGYNE 420
Query: 421 WREFCGLPRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTGPLF 480
WREFCGLPRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTGPLF
Sbjct: 421 WREFCGLPRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTGPLF 480
Query: 481 ACLIGKQMKALRDGDWFWWENSHVFTDAQRRELEKHSLSRVICDNTGLTRVPMDAFQVGK 540
ACLIGKQMKALRDGDWFWWENSHVFTDAQRRELEKHSLSRVICDNTGLTRVPMDAFQVGK
Sbjct: 481 ACLIGKQMKALRDGDWFWWENSHVFTDAQRRELEKHSLSRVICDNTGLTRVPMDAFQVGK 540
Query: 541 FPEDFESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYE 600
FPEDFESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYE
Sbjct: 541 FPEDFESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYE 600
Query: 601 LQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGD 660
LQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGD
Sbjct: 601 LQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGD 660
Query: 661 DGRTCVDSGRLPRVTWISMSLAALLIGGFAGLTSTVICRWTRTGTKSTLPISETGGGTPE 720
DGRTCVDSGRLPRVTWISMSLAALLIGGFAGLTSTVICRWTRTGTKSTLPISETGGGTPE
Sbjct: 661 DGRTCVDSGRLPRVTWISMSLAALLIGGFAGLTSTVICRWTRTGTKSTLPISETGGGTPE 720
Query: 721 LRCGKHQAVGTSPQRAAAQDSEQESAGMEGRDTHRLPRAL 760
LRCGKHQAVGTSPQRAAAQDSEQESAGMEGRDTHRLPRAL
Sbjct: 721 LRCGKHQAVGTSPQRAAAQDSEQESAGMEGRDTHRLPRAL 760
>gi|28558982 thyroid peroxidase isoform a [Homo sapiens]
Length = 933
Score = 1025 bits (2651), Expect = 0.0
Identities = 488/488 (100%), Positives = 488/488 (100%)
Query: 273 QIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLD 332
QIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLD
Sbjct: 446 QIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLD 505
Query: 333 ASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLF 392
ASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLF
Sbjct: 506 ASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLF 565
Query: 393 VLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDL 452
VLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDL
Sbjct: 566 VLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDL 625
Query: 453 YKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRE 512
YKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRE
Sbjct: 626 YKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRE 685
Query: 513 LEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDKCGFP 572
LEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDKCGFP
Sbjct: 686 LEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDKCGFP 745
Query: 573 ESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAH 632
ESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAH
Sbjct: 746 ESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAH 805
Query: 633 PPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRVTWISMSLAALLIGGFAGL 692
PPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRVTWISMSLAALLIGGFAGL
Sbjct: 806 PPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRVTWISMSLAALLIGGFAGL 865
Query: 693 TSTVICRWTRTGTKSTLPISETGGGTPELRCGKHQAVGTSPQRAAAQDSEQESAGMEGRD 752
TSTVICRWTRTGTKSTLPISETGGGTPELRCGKHQAVGTSPQRAAAQDSEQESAGMEGRD
Sbjct: 866 TSTVICRWTRTGTKSTLPISETGGGTPELRCGKHQAVGTSPQRAAAQDSEQESAGMEGRD 925
Query: 753 THRLPRAL 760
THRLPRAL
Sbjct: 926 THRLPRAL 933
Score = 564 bits (1453), Expect = e-160
Identities = 273/274 (99%), Positives = 274/274 (100%)
Query: 1 MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR 60
MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR
Sbjct: 1 MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR 60
Query: 61 NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS 120
NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS
Sbjct: 61 NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS 120
Query: 121 EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV 180
EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV
Sbjct: 121 EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV 180
Query: 181 YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD 240
YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD
Sbjct: 181 YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD 240
Query: 241 IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQI 274
IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQ+
Sbjct: 241 IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQL 274
>gi|28558988 thyroid peroxidase isoform d [Homo sapiens]
Length = 889
Score = 904 bits (2335), Expect = 0.0
Identities = 444/488 (90%), Positives = 444/488 (90%), Gaps = 44/488 (9%)
Query: 273 QIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLD 332
QIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLD
Sbjct: 446 QIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLD 505
Query: 333 ASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLF 392
ASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLF
Sbjct: 506 ASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLF 565
Query: 393 VLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDL 452
VLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDL
Sbjct: 566 VLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDL 625
Query: 453 YKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRE 512
YKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRE
Sbjct: 626 YKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRE 685
Query: 513 LEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDKCGFP 572
LEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDKCGFP
Sbjct: 686 LEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDKCGFP 745
Query: 573 ESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAH 632
ESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCK
Sbjct: 746 ESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCK---------- 795
Query: 633 PPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRVTWISMSLAALLIGGFAGL 692
DSGRLPRVTWISMSLAALLIGGFAGL
Sbjct: 796 ----------------------------------DSGRLPRVTWISMSLAALLIGGFAGL 821
Query: 693 TSTVICRWTRTGTKSTLPISETGGGTPELRCGKHQAVGTSPQRAAAQDSEQESAGMEGRD 752
TSTVICRWTRTGTKSTLPISETGGGTPELRCGKHQAVGTSPQRAAAQDSEQESAGMEGRD
Sbjct: 822 TSTVICRWTRTGTKSTLPISETGGGTPELRCGKHQAVGTSPQRAAAQDSEQESAGMEGRD 881
Query: 753 THRLPRAL 760
THRLPRAL
Sbjct: 882 THRLPRAL 889
Score = 564 bits (1453), Expect = e-160
Identities = 273/274 (99%), Positives = 274/274 (100%)
Query: 1 MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR 60
MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR
Sbjct: 1 MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR 60
Query: 61 NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS 120
NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS
Sbjct: 61 NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS 120
Query: 121 EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV 180
EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV
Sbjct: 121 EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV 180
Query: 181 YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD 240
YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD
Sbjct: 181 YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD 240
Query: 241 IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQI 274
IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQ+
Sbjct: 241 IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQL 274
>gi|28558984 thyroid peroxidase isoform b [Homo sapiens]
Length = 876
Score = 885 bits (2287), Expect = 0.0
Identities = 430/488 (88%), Positives = 431/488 (88%), Gaps = 57/488 (11%)
Query: 273 QIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLD 332
QIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLD
Sbjct: 446 QIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLD 505
Query: 333 ASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLF 392
ASFQEHPDLPGLWLHQAFFSPWT L+RG
Sbjct: 506 ASFQEHPDLPGLWLHQAFFSPWT---------LLRG------------------------ 532
Query: 393 VLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDL 452
GYNEWREFCGLPRLETPADLSTAIASRSVADKILDL
Sbjct: 533 ------------------------GYNEWREFCGLPRLETPADLSTAIASRSVADKILDL 568
Query: 453 YKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRE 512
YKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRE
Sbjct: 569 YKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRE 628
Query: 513 LEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDKCGFP 572
LEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDKCGFP
Sbjct: 629 LEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDKCGFP 688
Query: 573 ESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAH 632
ESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAH
Sbjct: 689 ESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAH 748
Query: 633 PPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRVTWISMSLAALLIGGFAGL 692
PPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRVTWISMSLAALLIGGFAGL
Sbjct: 749 PPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRVTWISMSLAALLIGGFAGL 808
Query: 693 TSTVICRWTRTGTKSTLPISETGGGTPELRCGKHQAVGTSPQRAAAQDSEQESAGMEGRD 752
TSTVICRWTRTGTKSTLPISETGGGTPELRCGKHQAVGTSPQRAAAQDSEQESAGMEGRD
Sbjct: 809 TSTVICRWTRTGTKSTLPISETGGGTPELRCGKHQAVGTSPQRAAAQDSEQESAGMEGRD 868
Query: 753 THRLPRAL 760
THRLPRAL
Sbjct: 869 THRLPRAL 876
Score = 564 bits (1453), Expect = e-160
Identities = 273/274 (99%), Positives = 274/274 (100%)
Query: 1 MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR 60
MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR
Sbjct: 1 MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR 60
Query: 61 NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS 120
NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS
Sbjct: 61 NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS 120
Query: 121 EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV 180
EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV
Sbjct: 121 EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV 180
Query: 181 YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD 240
YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD
Sbjct: 181 YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD 240
Query: 241 IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQI 274
IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQ+
Sbjct: 241 IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQL 274
>gi|4557759 myeloperoxidase [Homo sapiens]
Length = 745
Score = 292 bits (747), Expect = 9e-79
Identities = 137/291 (47%), Positives = 194/291 (66%), Gaps = 2/291 (0%)
Query: 272 IQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRL 331
+QIIT RDY+P +LGP A ++Y+ Y Y+ + +P ++NVF T AFR+GH I P + RL
Sbjct: 454 VQIITYRDYLPLVLGPTAMRKYLPTYRSYNDSVDPRIANVF-TNAFRYGHTLIQPFMFRL 512
Query: 332 DASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERL 391
D +Q P + L + FF+ W ++ GG+DP++RGL+A PAKL Q+Q+ +E+ ERL
Sbjct: 513 DNRYQPMEPNPRVPLSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERL 572
Query: 392 FVLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILD 451
F LDL ++N+QR RDHGLPGYN WR FCGLP+ ET L T + + +A K+++
Sbjct: 573 FEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNLKLARKLME 632
Query: 452 LYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRR 511
Y P+NID+W+GG++E + R GPL AC+IG Q + LRDGD FWWEN VF+ QR+
Sbjct: 633 QYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIGTQFRKLRDGDRFWWENEGVFSMQQRQ 692
Query: 512 ELEKHSLSRVICDNTGLTRVPM-DAFQVGKFPEDFESCDSITGMNLEAWRE 561
L + SL R+ICDNTG+T V + F +P DF +C ++ +NL +WRE
Sbjct: 693 ALAQISLPRIICDNTGITTVSKNNIFMSNSYPRDFVNCSTLPALNLASWRE 743
Score = 189 bits (479), Expect = 1e-47
Identities = 97/246 (39%), Positives = 145/246 (58%), Gaps = 7/246 (2%)
Query: 32 GKPEESRVSSVLEESKRLVDTAMYATMQRNLKKR---GILSPAQLLSFSKLPEPTSGVIA 88
G+ + S V S +EE+K+LVD A Y + ++K+R G SP +LLS+ K P +
Sbjct: 55 GEVDTSLVLSSMEEAKQLVDKA-YKERRESIKQRLRSGSASPMELLSYFKQPVAATRTAV 113
Query: 89 RAAEIMETSIQAMKRKVNLKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLA 148
RAA+ + ++ ++RK+ ++ + TD L+ L++++ SGC + CP
Sbjct: 114 RAADYLHVALDLLERKLRSLWRRPFNVTDVLTPAQLNVLSKSSGCAYQDVGVTCPEQ--- 170
Query: 149 NKYRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREV 208
+KYR ITG CNNR P GASN A RWLP YEDGFS P GW PG NGFP+ R V
Sbjct: 171 DKYRTITGMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALARAV 230
Query: 209 TRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNP 268
+ +++ + +T D S + M WGQ +DHD+ FTP+ ++A+F G +C+ +C Q P
Sbjct: 231 SNEIVRFPTDQLTPDQERSLMFMQWGQLLDHDLDFTPEPAARASFVTGVNCETSCVQQPP 290
Query: 269 CFPIQI 274
CFP++I
Sbjct: 291 CFPLKI 296
>gi|4503595 eosinophil peroxidase [Homo sapiens]
Length = 715
Score = 292 bits (747), Expect = 9e-79
Identities = 141/291 (48%), Positives = 189/291 (64%), Gaps = 1/291 (0%)
Query: 272 IQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRL 331
+QIIT RD++P +LG ++ +G Y GY S +P V+NVF T AFRFGH + P + RL
Sbjct: 426 VQIITYRDFLPLVLGKARARRTLGHYRGYCSNVDPRVANVF-TLAFRFGHTMLQPFMFRL 484
Query: 332 DASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERL 391
D+ ++ + L AFF+ W ++ GG+DP++RGL+A PAKL QD ++ +EL +RL
Sbjct: 485 DSQYRASAPNSHVPLSSAFFASWRIVYEGGIDPILRGLMATPAKLNRQDAMLVDELRDRL 544
Query: 392 FVLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILD 451
F LDLA++N+QR RDHGLPGYN WR FCGL + A LS + ++ +A K L+
Sbjct: 545 FRQVRRIGLDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNQDLARKFLN 604
Query: 452 LYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRR 511
LY PDNID+W+G +AE LP AR GPL ACL Q + RDGD FWW+ VFT QR+
Sbjct: 605 LYGTPDNIDIWIGAIAEPLLPGARVGPLLACLFENQFRRARDGDRFWWQKRGVFTKRQRK 664
Query: 512 ELEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRET 562
L + SLSR+ICDNTG+T V D F+ +P F +C I +NL AWR T
Sbjct: 665 ALSRISLSRIICDNTGITTVSRDIFRANIYPRGFVNCSRIPRLNLSAWRGT 715
Score = 187 bits (475), Expect = 3e-47
Identities = 101/246 (41%), Positives = 142/246 (57%), Gaps = 9/246 (3%)
Query: 32 GKPEESRVSSVLEESKRLVDTAMYATMQRNLKKR---GILSPAQLLSFSKLPEPTSGVIA 88
G E S + + E+K LVD A Y Q+++K+R G SP LLS+ K P + +
Sbjct: 29 GAVETSVLRDCIAEAKLLVDAA-YNWTQKSIKQRLRSGSASPMDLLSYFKQPVAATRTVV 87
Query: 89 RAAEIMETSIQAMKRKVNLKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLA 148
RAA+ M ++ ++ K+ + + TD L+E L +++ SGC +C +
Sbjct: 88 RAADYMHVALGLLEEKLQPQRSGPFNVTDVLTEPQLRLLSQASGCALRDQAERC-----S 142
Query: 149 NKYRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREV 208
+KYR ITG CNN+ P GASN ALARWLP YEDG S P GW P NGF LP VR V
Sbjct: 143 DKYRTITGRCNNKRRPLLGASNQALARWLPAEYEDGLSLPFGWTPSRRRNGFLLPLVRAV 202
Query: 209 TRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNP 268
+ +++ NE +T D + + M WGQ+IDHD+ F+P+S ++ AF G DC+ TC P
Sbjct: 203 SNQIVRFPNERLTSDRGRALMFMQWGQFIDHDLDFSPESPARVAFTAGVDCERTCAQLPP 262
Query: 269 CFPIQI 274
CFPI+I
Sbjct: 263 CFPIKI 268
>gi|231569458 lactoperoxidase isoform 3 preproprotein [Homo sapiens]
Length = 629
Score = 291 bits (744), Expect = 2e-78
Identities = 139/289 (48%), Positives = 195/289 (67%), Gaps = 3/289 (1%)
Query: 272 IQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRL 331
+QIIT RDY+P +LG + Q+++ PY+GY + +P +SNVF T AFRFGH + + RL
Sbjct: 338 VQIITFRDYLPILLG-DHMQKWIPPYQGYSESVDPRISNVF-TFAFRFGHLEVPSSMFRL 395
Query: 332 DASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERL 391
D ++Q P L LH FF+ W +++ GG+DPL+RGLLA+ +KL Q+++M EL +L
Sbjct: 396 DENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKL 455
Query: 392 FVLSNS-STLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKIL 450
F ++ DLA+IN QR RDHG PGYN WR FC L + +T +L+T + S+ +A K+L
Sbjct: 456 FQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLL 515
Query: 451 DLYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQR 510
LY PDNID+W+G +AE + R R GPL ACL+GKQ + +RDGD FWWEN VFT+ Q+
Sbjct: 516 GLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQK 575
Query: 511 RELEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAW 559
L+K S SR++CDNT +T+VP D F +P DF C +I ++L W
Sbjct: 576 DSLQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPW 624
Score = 121 bits (304), Expect = 2e-27
Identities = 60/122 (49%), Positives = 70/122 (57%)
Query: 151 YRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREVTR 210
YR ITG CNNR P GA+N ALARWLP YEDG S P GW PG NGFPLP REV+
Sbjct: 55 YRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSN 114
Query: 211 HVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCF 270
++ NE D S L M WGQ +DHD+ F P + ++ A C C + CF
Sbjct: 115 KIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCF 174
Query: 271 PI 272
PI
Sbjct: 175 PI 176
>gi|40549418 lactoperoxidase isoform 1 preproprotein [Homo sapiens]
Length = 712
Score = 291 bits (744), Expect = 2e-78
Identities = 139/289 (48%), Positives = 195/289 (67%), Gaps = 3/289 (1%)
Query: 272 IQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRL 331
+QIIT RDY+P +LG + Q+++ PY+GY + +P +SNVF T AFRFGH + + RL
Sbjct: 421 VQIITFRDYLPILLG-DHMQKWIPPYQGYSESVDPRISNVF-TFAFRFGHLEVPSSMFRL 478
Query: 332 DASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERL 391
D ++Q P L LH FF+ W +++ GG+DPL+RGLLA+ +KL Q+++M EL +L
Sbjct: 479 DENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKL 538
Query: 392 FVLSNS-STLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKIL 450
F ++ DLA+IN QR RDHG PGYN WR FC L + +T +L+T + S+ +A K+L
Sbjct: 539 FQPTHRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLL 598
Query: 451 DLYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQR 510
LY PDNID+W+G +AE + R R GPL ACL+GKQ + +RDGD FWWEN VFT+ Q+
Sbjct: 599 GLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQK 658
Query: 511 RELEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAW 559
L+K S SR++CDNT +T+VP D F +P DF C +I ++L W
Sbjct: 659 DSLQKMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPW 707
Score = 128 bits (321), Expect = 2e-29
Identities = 85/238 (35%), Positives = 119/238 (50%), Gaps = 12/238 (5%)
Query: 37 SRVSSVLEESKRLVDTAMYATMQRNLKKRGILSPA--QLLSFSKLPEPTSGVIARAAEIM 94
S +S + ++K V+ A + R +P QL + K + + R ++
Sbjct: 32 SAISDTVSQAKVQVNKAFLDSRTRLKTAMSSETPTSRQLSEYLKHAKGRTRTAIRNGQVW 91
Query: 95 ETSIQAMKRKVNLKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPI 154
E S++ +++K +L + TD S DL S+ + GC +C + C + YR I
Sbjct: 92 EESLKRLRQKASLT-----NVTDP-SLDLTSLSLEV-GCGAPAPVVRC-DPC--SPYRTI 141
Query: 155 TGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQ 214
TG CNNR P GA+N ALARWLP YEDG S P GW PG NGFPLP REV+ ++
Sbjct: 142 TGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVG 201
Query: 215 VSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCFPI 272
NE D S L M WGQ +DHD+ F P + ++ A C C + CFPI
Sbjct: 202 YLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPI 259
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 256 bits (655), Expect = 4e-68
Identities = 130/293 (44%), Positives = 190/293 (64%), Gaps = 7/293 (2%)
Query: 272 IQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRL 331
IQ IT + ++P+ILG E + +G Y GYD N + N F+TAAFRFGH ++PL+ RL
Sbjct: 1026 IQHITYQHWLPKILG-EVGMRTLGEYHGYDPGINAGIFNAFATAAFRFGHTLVNPLLYRL 1084
Query: 332 DASFQE--HPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTE 389
D +FQ LP LH+AFFSP+ ++ GG+DPL+RGL K++V QL+N ELTE
Sbjct: 1085 DENFQPIAQDHLP---LHKAFFSPFRIVNEGGIDPLLRGLFGVAGKMRVPSQLLNTELTE 1141
Query: 390 RLFVLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKI 449
RLF ++++ LDLA+IN+QRGRDHG+P Y+++R +C L T DL I + + +K+
Sbjct: 1142 RLFSMAHTVALDLAAINIQRGRDHGIPPYHDYRVYCNLSAAHTFEDLKNEIKNPEIREKL 1201
Query: 450 LDLYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQ 509
LY NID++ + E+ +P +R GP CL+ Q K LRDGD W+EN VF+ AQ
Sbjct: 1202 KRLYGSTLNIDLFPALVVEDLVPGSRLGPTLMCLLSTQFKRLRDGDRLWYENPGVFSPAQ 1261
Query: 510 RRELEKHSLSRVICDNT-GLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRE 561
++++ SL+R++CDN +TRV D F+V +FP + SCD I ++L W++
Sbjct: 1262 LTQIKQTSLARILCDNADNITRVQSDVFRVAEFPHGYGSCDEIPRVDLRVWQD 1314
Score = 161 bits (407), Expect = 2e-39
Identities = 94/242 (38%), Positives = 129/242 (53%), Gaps = 9/242 (3%)
Query: 39 VSSVLEESKRLVDTAMYATMQRNLKKRGILSPAQLLSFSKLP-EPTSGVIARAAEIMETS 97
V++ + E+ VD A+ +T R SP LL+ + P +P + ARA EI E +
Sbjct: 624 VATSIVEAIATVDRAINSTRTHLFDSRP-RSPNDLLALFRYPRDPYTVEQARAGEIFERT 682
Query: 98 IQAMKRKVNLKTQ-----QSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLANKYR 152
+Q ++ V S H D +S L++IAN+SGC + C + C KYR
Sbjct: 683 LQLIQEHVQHGLMVDLNGTSYHYNDLVSPQYLNLIANLSGCTAHRRVNNCSDMCFHQKYR 742
Query: 153 PITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREVTRHV 212
G CNN HP WGAS TA R L VYE+GF+ PRG NP LYNG LP R V+ +
Sbjct: 743 THDGTCNNLQHPMWGASLTAFERLLKSVYENGFNTPRGINPHRLYNGHALPMPRLVSTTL 802
Query: 213 IQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCFPI 272
I E VT D++++ +LM WGQ++DHD+ T + S+A F G C C N PCF +
Sbjct: 803 I--GTETVTPDEQFTHMLMQWGQFLDHDLDSTVVALSQARFSDGQHCSNVCSNDPPCFSV 860
Query: 273 QI 274
I
Sbjct: 861 MI 862
>gi|126517478 peroxidasin homolog-like [Homo sapiens]
Length = 1463
Score = 224 bits (571), Expect = 2e-58
Identities = 115/291 (39%), Positives = 175/291 (60%), Gaps = 3/291 (1%)
Query: 272 IQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRL 331
+Q IT ++P++LG + G Y GY+ N + N F+TAAFRFGH I+P++ RL
Sbjct: 1009 LQHITYSHWLPKVLGDPGTRMLRG-YRGYNPNVNAGIINSFATAAFRFGHTLINPILYRL 1067
Query: 332 DASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERL 391
+A+ E + L H+A FSP +++ GG+DP++RGL AK + L++ ELT+RL
Sbjct: 1068 NATLGEISE-GHLPFHKALFSPSRIIKEGGIDPVLRGLFGVAAKWRAPSYLLSPELTQRL 1126
Query: 392 FVLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILD 451
F + S+ +D A+ +QRGRDHG+P Y ++R FC L ++ DL I + K+
Sbjct: 1127 FSAAYSAAVDSAATIIQRGRDHGIPPYVDFRVFCNLTSVKNFEDLQNEIKDSEIRQKLRK 1186
Query: 452 LYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRR 511
LY P +ID+W + E+ +P R GP CL Q + LRDGD FW+EN VFT AQ
Sbjct: 1187 LYGSPGDIDLWPALMVEDLIPGTRVGPTLMCLFVTQFQRLRDGDRFWYENPGVFTPAQLT 1246
Query: 512 ELEKHSLSRVICDN-TGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRE 561
+L++ SLSRV+CDN + +V D F ++P+D+ +C I ++L W++
Sbjct: 1247 QLKQASLSRVLCDNGDSIQQVQADVFVKAEYPQDYLNCSEIPKVDLRVWQD 1297
Score = 138 bits (348), Expect = 2e-32
Identities = 86/239 (35%), Positives = 123/239 (51%), Gaps = 11/239 (4%)
Query: 40 SSVLEESKRLVDTAMYATMQRNLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQ 99
SS+L+ +R VD+A+ +T + ++ S L F +P +ARA EI E ++Q
Sbjct: 612 SSILDAVQR-VDSAINSTRRHLFSQKPHTSSDLLAQFHYPRDPLIVEMARAGEIFEHTLQ 670
Query: 100 AMKRK------VNLKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLANKYRP 153
++ + V+L+ ++ ++ D +S LS+IAN+SGC P C N C KYR
Sbjct: 671 LIRERVKQGLTVDLEGKEFRY-NDLVSPRSLSLIANLSGCTARRPLPNCSNRCFHAKYRA 729
Query: 154 ITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVI 213
G CNN P WGA+ TA AR L P Y DG PRG + + PLPP R V +
Sbjct: 730 HDGTCNNLQQPTWGAALTAFARLLQPAYRDGIRAPRGLGLP-VGSRQPLPPPRLVA--TV 786
Query: 214 QVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCFPI 272
VT D Y+ +LM WG +++HD+ T + S A F G C C N PCFP+
Sbjct: 787 WARAAAVTPDHSYTRMLMHWGWFLEHDLDHTVPALSTARFSDGRPCSSVCTNDPPCFPM 845
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 72.4 bits (176), Expect = 1e-12
Identities = 39/117 (33%), Positives = 55/117 (47%), Gaps = 7/117 (5%)
Query: 554 MNLEAWRETFPQDDK--CGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQ 611
+N W + P ++ CG P +ENG + + Y C +GY L G ++ CT
Sbjct: 1673 LNQGQWTQPLPHCERISCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTD 1732
Query: 612 EG-WDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
G W+ P C DV+ECA G+ C A C N G + C C PY DG+ C +
Sbjct: 1733 NGSWNGVSPSCLDVDECAVGS--DCSEHASCLNVDGSYICSCVPPYT--GDGKNCAE 1785
Score = 48.1 bits (113), Expect = 3e-05
Identities = 34/107 (31%), Positives = 49/107 (45%), Gaps = 8/107 (7%)
Query: 568 KCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WDFQPPLCKDVNE 626
+C P + NG + + + + C GY L G +LTC +G WD + PLCK VN
Sbjct: 2890 RCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVN- 2948
Query: 627 CA---DGAHPPCHASARCRNTKGGFQCLCADPYEL-GDDGRTCVDSG 669
C D AH + + G Q C Y+L G+ R C+ +G
Sbjct: 2949 CGPPEDLAHGFPNGFSFIHG--GHIQYQCFPGYKLHGNSSRRCLSNG 2993
Score = 47.0 bits (110), Expect = 7e-05
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 1/55 (1%)
Query: 568 KCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WDFQPPLC 621
KC PE++ NG ++ + YSC GY LQG + CT G WD PP C
Sbjct: 1904 KCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPAC 1958
Score = 47.0 bits (110), Expect = 7e-05
Identities = 30/117 (25%), Positives = 47/117 (40%), Gaps = 5/117 (4%)
Query: 559 WRETFP--QDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WD 615
W FP + CG + N V+ YSCR GY +QG L CT++G W
Sbjct: 3052 WSSGFPHCEHTSCGSLPMIPNAFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWS 3111
Query: 616 FQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGR--TCVDSGR 670
P+C+ ++ + + A+ + + C + Y + D TC GR
Sbjct: 3112 QPYPVCEPLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGR 3168
Score = 46.2 bits (108), Expect = 1e-04
Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 569 CGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECA 628
C P+ +ENG + S +++YSC G+++ G TC + GW P C + +C
Sbjct: 2556 CDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESGWSSSIPTCMPI-DCG 2614
Query: 629 DGAHPPCHASARCRNTKGGFQ 649
H + ++ +G F+
Sbjct: 2615 LPPHIDFGDCTKLKDDQGYFE 2635
Score = 46.2 bits (108), Expect = 1e-04
Identities = 34/118 (28%), Positives = 50/118 (42%), Gaps = 10/118 (8%)
Query: 557 EAWRETFPQDDK--CGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGW 614
E W +T + +K CG P VEN ++ YSC GY L+G + C + G
Sbjct: 3402 ETWTQTSAKCEKISCGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGT 3461
Query: 615 DFQPPLCKDVNE--CADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGR 670
PP+C+ V C +G C C +G LC +P + C++ GR
Sbjct: 3462 WTSPPICRAVCRFPCQNGG--ICQRPNACSCPEGWMGRLCEEPICI----LPCLNGGR 3513
Score = 44.7 bits (104), Expect = 3e-04
Identities = 33/107 (30%), Positives = 45/107 (42%), Gaps = 10/107 (9%)
Query: 569 CGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQE-GWDFQPPLCKDVNEC 627
C P V NG + L Y C GY L G E+ TC + WD P+C V
Sbjct: 2775 CKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPV--- 2831
Query: 628 ADGAHPPCHASARCRNTKGGFQ----CLCADPYEL-GDDGRTCVDSG 669
D + PP A+ + R + FQ C + + L G R C+ +G
Sbjct: 2832 -DCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANG 2877
Score = 44.3 bits (103), Expect = 4e-04
Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Query: 568 KCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WDFQPPLCKDVN 625
+C P+ + NG F + + + + YSC G+ L+G LTC + G WD P C ++
Sbjct: 2497 ECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIH 2555
Score = 42.4 bits (98), Expect = 0.002
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 5/70 (7%)
Query: 559 WRETFPQDD----KCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQ-EG 613
W F + CG PES E+G V + + ++Y C GYEL+G + C +
Sbjct: 3227 WEPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQ 3286
Query: 614 WDFQPPLCKD 623
W +CK+
Sbjct: 3287 WSGGVAICKE 3296
Score = 41.2 bits (95), Expect = 0.004
Identities = 34/129 (26%), Positives = 55/129 (42%), Gaps = 15/129 (11%)
Query: 519 SRVICDNTGLTR------VPMDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDK---- 568
SR+ C + G + +D VG + SC ++ G + + + D K
Sbjct: 1726 SRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAE 1785
Query: 569 ---CGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WDFQPPLCKDV 624
C P + ENG + + +SC+ GY+L G ++TC + G W+ P CK V
Sbjct: 1786 PIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAV 1845
Query: 625 NECADGAHP 633
+ C A P
Sbjct: 1846 S-CGKPAIP 1853
Score = 39.7 bits (91), Expect = 0.011
Identities = 24/65 (36%), Positives = 32/65 (49%), Gaps = 4/65 (6%)
Query: 565 QDDKCGFPESVENGDF-VHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WDFQPPLCK 622
++ +C P NG + +G V VYSC GY L+G + CT+ G W PLCK
Sbjct: 3295 KETRCETPLEFLNGKADIENRTTGPNV-VYSCNRGYSLEGPSEAHCTENGTWSHPVPLCK 3353
Query: 623 DVNEC 627
N C
Sbjct: 3354 P-NPC 3357
Score = 39.3 bits (90), Expect = 0.014
Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 12/91 (13%)
Query: 568 KCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WDFQPPLCKDVNE 626
+CG P S+ NG S ++ YSC G+ ++G ++ TC G W P C V+
Sbjct: 2145 RCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVS- 2203
Query: 627 CADGAHPPC-------HASARCRNTKGGFQC 650
C + PP H + R ++ +QC
Sbjct: 2204 CGE---PPKVENGFLEHTTGRIFESEVRYQC 2231
Score = 38.5 bits (88), Expect = 0.023
Identities = 22/77 (28%), Positives = 31/77 (40%), Gaps = 3/77 (3%)
Query: 551 ITGMNLEAWRETFP--QDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLT 608
IT + W P + CG P ENG + + Y C GY L G ++ +
Sbjct: 1827 ITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESS 1886
Query: 609 C-TQEGWDFQPPLCKDV 624
C W PP+C+ V
Sbjct: 1887 CLANSSWSHSPPVCEPV 1903
Score = 37.4 bits (85), Expect = 0.052
Identities = 27/100 (27%), Positives = 44/100 (44%), Gaps = 9/100 (9%)
Query: 569 CGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WDFQPPLCKDVNEC 627
CG P ++++ + R + Y+C+ GY L G + + C +G W C V+ C
Sbjct: 1963 CGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVS-C 2021
Query: 628 ADGAHPPC--HASARCRNTKGGFQCL--CADPYELGDDGR 663
+ PP HAS + G C+D Y L D+ +
Sbjct: 2022 DE---PPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQ 2058
Score = 36.2 bits (82), Expect = 0.12
Identities = 33/94 (35%), Positives = 42/94 (44%), Gaps = 10/94 (10%)
Query: 593 YSCRHGYELQGREQLTCTQEG-WDFQPPLCKDVNECADGAHPPCHASARCRNTKGG--FQ 649
Y+C GYEL G L C ++G W+ P C + EC D P + R T G Q
Sbjct: 2683 YTCNPGYELLGNPVLICQEDGTWNGSAPSCISI-EC-DLPTAPENGFLRFTETSMGSAVQ 2740
Query: 650 CLCADPYEL-GDDGRTCVD----SGRLPRVTWIS 678
C + L G D R C++ SG PR IS
Sbjct: 2741 YSCKPGHILAGSDLRLCLENRKWSGASPRCEAIS 2774
Score = 33.1 bits (74), Expect = 0.99
Identities = 28/104 (26%), Positives = 42/104 (40%), Gaps = 6/104 (5%)
Query: 568 KCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQ-EGWDFQPPLCKDVNE 626
+C P + ENG E S + YSC+ G+ L G + C + W P C+ ++
Sbjct: 2716 ECDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAIS- 2774
Query: 627 CADGAHPPCHASARCRNTK--GGFQCLCADPYEL-GDDGRTCVD 667
+P + S + N C Y L G + RTC D
Sbjct: 2775 -CKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQD 2817
Score = 32.3 bits (72), Expect = 1.7
Identities = 21/72 (29%), Positives = 31/72 (43%), Gaps = 4/72 (5%)
Query: 559 WRETFPQ--DDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WD 615
W P+ +C PE + NG + +Y+C+ G+EL G C + G W
Sbjct: 2428 WSSPLPECVPVECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWL 2487
Query: 616 FQPPLCKDVNEC 627
P CK + EC
Sbjct: 2488 GGKPTCKAI-EC 2498
Score = 32.0 bits (71), Expect = 2.2
Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Query: 568 KCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTC-TQEGWDFQPPLCKDV 624
KC P +EN + + V+ +SC+ G+ LQG L C + W+ P+CK V
Sbjct: 2322 KCPEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIV 2379
Score = 31.6 bits (70), Expect = 2.9
Identities = 19/47 (40%), Positives = 25/47 (53%), Gaps = 4/47 (8%)
Query: 569 CGFPESVENGDFVHCE--ESGRRVLVYSCRHGYELQGREQLTCTQEG 613
CG P ++NG F+ E E G +V + C GYEL G TC + G
Sbjct: 2264 CGKPPPIQNG-FMKGENFEVGSKVQFF-CNEGYELVGDSSWTCQKSG 2308
Score = 30.4 bits (67), Expect = 6.4
Identities = 13/32 (40%), Positives = 18/32 (56%), Gaps = 3/32 (9%)
Query: 622 KDVNECADGAHPPCHASARCRNTKGGFQCLCA 653
K+V+EC PC A C++ F+CLCA
Sbjct: 1344 KNVDECLS---QPCKNGATCKDGANSFRCLCA 1372
>gi|20149640 dual oxidase 1 precursor [Homo sapiens]
Length = 1551
Score = 66.6 bits (161), Expect = 8e-11
Identities = 69/252 (27%), Positives = 121/252 (48%), Gaps = 23/252 (9%)
Query: 287 PEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDAS--FQ-----EHP 339
P Q+ + Y GY +P++S+ F A+ +F + P V +AS FQ
Sbjct: 297 PSFLQKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHFQGVINRNSS 356
Query: 340 DLPGLWLHQAFFSPW--TLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNS 397
L + +++S +L +D L+ G+ ++ A+ + D ++ E++ +
Sbjct: 357 VSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAERE--DHVLVEDVRDFWPGPLKF 414
Query: 398 STLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYKHPD 457
S D + LQRGRD GLP Y + R GL + D++ A++ + D +L+
Sbjct: 415 SRTDHLASCLQRGRDLGLPSYTKARAALGLSPITRWQDINPALSRSN--DTVLEATAALY 472
Query: 458 NIDV-WL----GGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSH--VFTDAQR 510
N D+ WL GGL E+ GPLF+ ++ +Q LRDGD +W+EN+ +F+ +
Sbjct: 473 NQDLSWLELLPGGLLES---HRDPGPLFSTIVLEQFVRLRDGDRYWFENTRNGLFSKKEI 529
Query: 511 RELEKHSLSRVI 522
E+ +L V+
Sbjct: 530 EEIRNTTLQDVL 541
Score = 32.0 bits (71), Expect = 2.2
Identities = 15/35 (42%), Positives = 18/35 (51%)
Query: 156 GACNNRDHPRWGASNTALARWLPPVYEDGFSQPRG 190
G NN RWG+ + L R +P Y DG QP G
Sbjct: 34 GWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLG 68
>gi|28872751 dual oxidase 1 precursor [Homo sapiens]
Length = 1551
Score = 66.6 bits (161), Expect = 8e-11
Identities = 69/252 (27%), Positives = 121/252 (48%), Gaps = 23/252 (9%)
Query: 287 PEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDAS--FQ-----EHP 339
P Q+ + Y GY +P++S+ F A+ +F + P V +AS FQ
Sbjct: 297 PSFLQKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHFQGVINRNSS 356
Query: 340 DLPGLWLHQAFFSPW--TLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFVLSNS 397
L + +++S +L +D L+ G+ ++ A+ + D ++ E++ +
Sbjct: 357 VSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAERE--DHVLVEDVRDFWPGPLKF 414
Query: 398 STLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYKHPD 457
S D + LQRGRD GLP Y + R GL + D++ A++ + D +L+
Sbjct: 415 SRTDHLASCLQRGRDLGLPSYTKARAALGLSPITRWQDINPALSRSN--DTVLEATAALY 472
Query: 458 NIDV-WL----GGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSH--VFTDAQR 510
N D+ WL GGL E+ GPLF+ ++ +Q LRDGD +W+EN+ +F+ +
Sbjct: 473 NQDLSWLELLPGGLLES---HRDPGPLFSTIVLEQFVRLRDGDRYWFENTRNGLFSKKEI 529
Query: 511 RELEKHSLSRVI 522
E+ +L V+
Sbjct: 530 EEIRNTTLQDVL 541
Score = 32.0 bits (71), Expect = 2.2
Identities = 15/35 (42%), Positives = 18/35 (51%)
Query: 156 GACNNRDHPRWGASNTALARWLPPVYEDGFSQPRG 190
G NN RWG+ + L R +P Y DG QP G
Sbjct: 34 GWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLG 68
>gi|132566532 dual oxidase 2 precursor [Homo sapiens]
Length = 1548
Score = 65.5 bits (158), Expect = 2e-10
Identities = 65/252 (25%), Positives = 117/252 (46%), Gaps = 26/252 (10%)
Query: 287 PEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDAS----------FQ 336
P Q+ + Y GY +P++S F A+ +F + P V +AS FQ
Sbjct: 303 PSFLQKTLPEYTGYRPFLDPSISPEFVVASEQFFSTMVPPGVYMRNASCHFRKVLNKGFQ 362
Query: 337 EHPDLP---GLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLFV 393
L W+ + +P L ++ L+ G+ ++ ++L+ D ++ E+L +
Sbjct: 363 SSQALRVCNNYWIRE---NP-NLNSTQEVNELLLGMASQISELE--DNIVVEDLRDYWPG 416
Query: 394 LSNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDLY 453
S D + ++QRGRD GLP Y++ GL +DL+ + + V + LY
Sbjct: 417 PGKFSRTDYVASSIQRGRDMGLPSYSQALLAFGLDIPRNWSDLNPNVDPQ-VLEATAALY 475
Query: 454 KHP-DNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSH--VFTDAQR 510
+++ LGGL E+ GPLF+ ++ Q LRDGD +W+EN+ +F+ +
Sbjct: 476 NQDLSQLELLLGGLLES---HGDPGPLFSAIVLDQFVRLRDGDRYWFENTRNGLFSKKEI 532
Query: 511 RELEKHSLSRVI 522
++ +L V+
Sbjct: 533 EDIRNTTLRDVL 544
>gi|194328809 latent transforming growth factor beta binding protein
3 isoform 1 [Homo sapiens]
Length = 1303
Score = 64.3 bits (155), Expect = 4e-10
Identities = 43/128 (33%), Positives = 59/128 (46%), Gaps = 22/128 (17%)
Query: 541 FPEDFESCDSITGMNLEAWRETFPQD-DKCGFPESVENGDFVHCEESGRRVLVYSCRHGY 599
FP ++ C+ G L+A R +D D+C P S +G CE +C+ GY
Sbjct: 679 FPGHYK-CNCYPGYRLKASRPPVCEDIDECRDPSSCPDGK---CENKPGSFKCIACQPGY 734
Query: 600 ELQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELG 659
QG C+DVNECA+G+ PC + C N G F+C CA Y
Sbjct: 735 RSQGGGA--------------CRDVNECAEGS--PC-SPGWCENLPGSFRCTCAQGYAPA 777
Query: 660 DDGRTCVD 667
DGR+C+D
Sbjct: 778 PDGRSCLD 785
Score = 45.8 bits (107), Expect = 1e-04
Identities = 34/144 (23%), Positives = 56/144 (38%), Gaps = 30/144 (20%)
Query: 522 ICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFV 581
+CDN + P G F C ++G +L R D+C FP + GD +
Sbjct: 794 VCDNGICSNTP------GSF-----QCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCI 842
Query: 582 HCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARC 641
+ S R + C G+ L G + C+D++EC+ C C
Sbjct: 843 NTNGSYRCL----CPQGHRLVGGRK--------------CQDIDECSQDP-SLCLPHGAC 883
Query: 642 RNTKGGFQCLCADPYELGDDGRTC 665
+N +G + C+C + + D C
Sbjct: 884 KNLQGSYVCVCDEGFTPTQDQHGC 907
Score = 42.4 bits (98), Expect = 0.002
Identities = 29/78 (37%), Positives = 34/78 (43%), Gaps = 7/78 (8%)
Query: 595 CRHGYELQGREQLTC-TQEGWDFQPP--LCKDVNECADGAHPPCHASARCRNTKGGFQCL 651
C HG + G +C G+ P C DVNEC A P C NT G + C
Sbjct: 585 CGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECE--AEPCGPGRGICMNTGGSYNCH 642
Query: 652 CADPYEL--GDDGRTCVD 667
C Y L G GR+CVD
Sbjct: 643 CNRGYRLHVGAGGRSCVD 660
Score = 41.6 bits (96), Expect = 0.003
Identities = 46/191 (24%), Positives = 70/191 (36%), Gaps = 25/191 (13%)
Query: 577 NGDFVHCEESGRRVLVYSCRHGY--ELQGREQLTCTQEGWDFQP-------PLCKDVNEC 627
+G+ + C + + +CR+G +G + CT ++ P P DV+EC
Sbjct: 1028 DGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPA-EYSPAQRQCLSPEEMDVDEC 1086
Query: 628 ADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTC----VDSGRLPR---VTWISMS 680
D P RC N G ++C C P+ G GR C + R P V W
Sbjct: 1087 QD---PAACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRG 1143
Query: 681 LAALLIGGFAGLTST---VICRWTRTGTKSTLPISETGGGT--PELRCGKHQAVGTSPQR 735
+ G AG T CR R P G G+ P + + TSP
Sbjct: 1144 EDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLL 1203
Query: 736 AAAQDSEQESA 746
+++S+
Sbjct: 1204 LGKPPRDEDSS 1214
Score = 35.4 bits (80), Expect = 0.20
Identities = 15/46 (32%), Positives = 22/46 (47%), Gaps = 3/46 (6%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCV 666
C+D+NECA P C N G ++C+C + LG C+
Sbjct: 353 CQDINECA---MPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCI 395
Score = 31.6 bits (70), Expect = 2.9
Identities = 29/103 (28%), Positives = 38/103 (36%), Gaps = 20/103 (19%)
Query: 574 SVENGDFVHCEESGRRV-----LVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECA 628
S E+ D C SGR V V C G++L D C D++EC
Sbjct: 1214 SEEDSDECRCV-SGRCVPRPGGAVCECPGGFQL-------------DASRARCVDIDECR 1259
Query: 629 D-GAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGR 670
+ S RC NT G F+C+C + CV R
Sbjct: 1260 ELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQRR 1302
Score = 30.0 bits (66), Expect = 8.3
Identities = 14/49 (28%), Positives = 23/49 (46%), Gaps = 1/49 (2%)
Query: 619 PLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
P +D++EC C +C NT+ G++C C + + CVD
Sbjct: 989 PAHRDIDECMLFGSEICK-EGKCVNTQPGYECYCKQGFYYDGNLLECVD 1036
>gi|18497288 latent transforming growth factor beta binding protein
3 isoform 2 [Homo sapiens]
Length = 1256
Score = 64.3 bits (155), Expect = 4e-10
Identities = 43/128 (33%), Positives = 59/128 (46%), Gaps = 22/128 (17%)
Query: 541 FPEDFESCDSITGMNLEAWRETFPQD-DKCGFPESVENGDFVHCEESGRRVLVYSCRHGY 599
FP ++ C+ G L+A R +D D+C P S +G CE +C+ GY
Sbjct: 679 FPGHYK-CNCYPGYRLKASRPPVCEDIDECRDPSSCPDGK---CENKPGSFKCIACQPGY 734
Query: 600 ELQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELG 659
QG C+DVNECA+G+ PC + C N G F+C CA Y
Sbjct: 735 RSQGGGA--------------CRDVNECAEGS--PC-SPGWCENLPGSFRCTCAQGYAPA 777
Query: 660 DDGRTCVD 667
DGR+C+D
Sbjct: 778 PDGRSCLD 785
Score = 45.8 bits (107), Expect = 1e-04
Identities = 34/144 (23%), Positives = 56/144 (38%), Gaps = 30/144 (20%)
Query: 522 ICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFV 581
+CDN + P G F C ++G +L R D+C FP + GD +
Sbjct: 794 VCDNGICSNTP------GSF-----QCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCI 842
Query: 582 HCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARC 641
+ S R + C G+ L G + C+D++EC+ C C
Sbjct: 843 NTNGSYRCL----CPQGHRLVGGRK--------------CQDIDECSQDP-SLCLPHGAC 883
Query: 642 RNTKGGFQCLCADPYELGDDGRTC 665
+N +G + C+C + + D C
Sbjct: 884 KNLQGSYVCVCDEGFTPTQDQHGC 907
Score = 44.7 bits (104), Expect = 3e-04
Identities = 36/137 (26%), Positives = 52/137 (37%), Gaps = 14/137 (10%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPR------V 674
C DV+EC D ++ C C NT+GG++C C P E R C+ + R V
Sbjct: 1034 CVDVDECLDESN--CRNGV-CENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPERRDV 1090
Query: 675 TWISMSLAALLIGGFAGLTST---VICRWTRTGTKSTLPISETGGGT--PELRCGKHQAV 729
W + G AG T CR R P G G+ P + +
Sbjct: 1091 CWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFW 1150
Query: 730 GTSPQRAAAQDSEQESA 746
TSP +++S+
Sbjct: 1151 DTSPLLLGKPPRDEDSS 1167
Score = 42.4 bits (98), Expect = 0.002
Identities = 29/78 (37%), Positives = 34/78 (43%), Gaps = 7/78 (8%)
Query: 595 CRHGYELQGREQLTC-TQEGWDFQPP--LCKDVNECADGAHPPCHASARCRNTKGGFQCL 651
C HG + G +C G+ P C DVNEC A P C NT G + C
Sbjct: 585 CGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECE--AEPCGPGRGICMNTGGSYNCH 642
Query: 652 CADPYEL--GDDGRTCVD 667
C Y L G GR+CVD
Sbjct: 643 CNRGYRLHVGAGGRSCVD 660
Score = 35.4 bits (80), Expect = 0.20
Identities = 15/46 (32%), Positives = 22/46 (47%), Gaps = 3/46 (6%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCV 666
C+D+NECA P C N G ++C+C + LG C+
Sbjct: 353 CQDINECA---MPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCI 395
Score = 31.6 bits (70), Expect = 2.9
Identities = 29/103 (28%), Positives = 38/103 (36%), Gaps = 20/103 (19%)
Query: 574 SVENGDFVHCEESGRRV-----LVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECA 628
S E+ D C SGR V V C G++L D C D++EC
Sbjct: 1167 SEEDSDECRCV-SGRCVPRPGGAVCECPGGFQL-------------DASRARCVDIDECR 1212
Query: 629 D-GAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGR 670
+ S RC NT G F+C+C + CV R
Sbjct: 1213 ELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQRR 1255
Score = 30.0 bits (66), Expect = 8.3
Identities = 14/49 (28%), Positives = 23/49 (46%), Gaps = 1/49 (2%)
Query: 619 PLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
P +D++EC C +C NT+ G++C C + + CVD
Sbjct: 989 PAHRDIDECMLFGSEICK-EGKCVNTQPGYECYCKQGFYYDGNLLECVD 1036
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 54.7 bits (130), Expect = 3e-07
Identities = 25/47 (53%), Positives = 30/47 (63%), Gaps = 1/47 (2%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C DV+ECA G C + +C NT G FQC C + YE+ DGRTCVD
Sbjct: 1928 CIDVDECASGNGNLCR-NGQCINTVGSFQCQCNEGYEVAPDGRTCVD 1973
Score = 52.8 bits (125), Expect = 1e-06
Identities = 46/170 (27%), Positives = 67/170 (39%), Gaps = 37/170 (21%)
Query: 522 ICDNTGLTRVP-------MDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDKCGFPES 574
ICD T +P D F ED ++C + +L P G E+
Sbjct: 1248 ICDGGQCTNIPGEYRCLCYDGFMAS---EDMKTCVDVNECDLN------PNICLSGTCEN 1298
Query: 575 VENGDFVHCEE--SGRR-----VLVYSCRHGYELQGREQLTCTQE----------GWDFQ 617
+ HC+ SG++ + C G G+ + CT GW
Sbjct: 1299 TKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAV-CTNTAGSFKCSCSPGWIGD 1357
Query: 618 PPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C D++EC++G H C A C+NT G ++CLC + Y DG TC D
Sbjct: 1358 GIKCTDLDECSNGTHM-CSQHADCKNTMGSYRCLCKEGYT--GDGFTCTD 1404
Score = 51.2 bits (121), Expect = 3e-06
Identities = 28/89 (31%), Positives = 42/89 (47%), Gaps = 6/89 (6%)
Query: 579 DFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHAS 638
D C R+ +C++ L G + C G+ Q C+D++EC + P A
Sbjct: 1973 DINECLLEPRKCAPGTCQN---LDGSYRCICPP-GYSLQNEKCEDIDECVE--EPEICAL 2026
Query: 639 ARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C NT+G F+CLC + + L GR C D
Sbjct: 2027 GTCSNTEGSFKCLCPEGFSLSSSGRRCQD 2055
Score = 51.2 bits (121), Expect = 3e-06
Identities = 34/98 (34%), Positives = 46/98 (46%), Gaps = 6/98 (6%)
Query: 595 CRHGYELQGREQLTCT-QEGW--DFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCL 651
CR+G + R C + G+ D C D+NEC + A PC+ C+NT+G +QC
Sbjct: 2413 CRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNEC-NQAPKPCNFI--CKNTEGSYQCS 2469
Query: 652 CADPYELGDDGRTCVDSGRLPRVTWISMSLAALLIGGF 689
C Y L +DGR+C D L IGGF
Sbjct: 2470 CPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGF 2507
Score = 50.4 bits (119), Expect = 6e-06
Identities = 37/127 (29%), Positives = 55/127 (43%), Gaps = 34/127 (26%)
Query: 567 DKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGRE--------------------- 605
D+C P+ ++G ++ + S R C GY L G E
Sbjct: 2129 DECKEPDVCKHGQCINTDGSYR----CECPFGYILAGNECVDTDECSVGNPCGNGTCKNV 2184
Query: 606 ----QLTCTQEGWDFQPPL-CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGD 660
+ TC +EG++ P + C+D+NECA P + RC NT G ++C C Y L +
Sbjct: 2185 IGGFECTC-EEGFEPGPMMTCEDINECAQN---PLLCAFRCVNTYGSYECKCPVGYVLRE 2240
Query: 661 DGRTCVD 667
D R C D
Sbjct: 2241 DRRMCKD 2247
Score = 47.8 bits (112), Expect = 4e-05
Identities = 18/48 (37%), Positives = 25/48 (52%)
Query: 620 LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
+CKD +EC +G H C+N G + C+C Y+ DG CVD
Sbjct: 2244 MCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVD 2291
Score = 45.8 bits (107), Expect = 1e-04
Identities = 21/48 (43%), Positives = 27/48 (56%), Gaps = 3/48 (6%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 668
CKD+NEC P + RC NT G ++C C +G DGR CVD+
Sbjct: 611 CKDINECET---PGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDT 655
Score = 44.7 bits (104), Expect = 3e-04
Identities = 23/68 (33%), Positives = 36/68 (52%), Gaps = 5/68 (7%)
Query: 602 QGREQLTCTQEGWDFQPPL--CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELG 659
+G + +C Q G+ P C D++EC D +P +C N G ++CLC D +
Sbjct: 1216 EGSYECSC-QPGFALMPDQRSCTDIDECED--NPNICDGGQCTNIPGEYRCLCYDGFMAS 1272
Query: 660 DDGRTCVD 667
+D +TCVD
Sbjct: 1273 EDMKTCVD 1280
Score = 42.7 bits (99), Expect = 0.001
Identities = 33/124 (26%), Positives = 49/124 (39%), Gaps = 29/124 (23%)
Query: 548 CDSITGMNLEAWRETFPQDD----KCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQG 603
C+ G L+ E D+ C E + N C+ CR GY+
Sbjct: 474 CECNKGFQLDLRGECIDVDECEKNPCAGGECINNQGSYTCQ----------CRAGYQ--- 520
Query: 604 REQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGR 663
LT T+ C+D++EC C+ + RC NT G F C+C + + DG+
Sbjct: 521 -STLTRTE---------CRDIDECLQNGRI-CN-NGRCINTDGSFHCVCNAGFHVTRDGK 568
Query: 664 TCVD 667
C D
Sbjct: 569 NCED 572
Score = 41.6 bits (96), Expect = 0.003
Identities = 19/49 (38%), Positives = 24/49 (48%), Gaps = 2/49 (4%)
Query: 619 PLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
P KD+NEC P +CRNT G F+C C + L + R C D
Sbjct: 1024 PFFKDINECK--MIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTD 1070
Score = 41.2 bits (95), Expect = 0.004
Identities = 17/45 (37%), Positives = 25/45 (55%), Gaps = 2/45 (4%)
Query: 623 DVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
D+NECA P + C N +G ++C+C YE+ G+ CVD
Sbjct: 723 DINECA--LDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVD 765
Score = 40.8 bits (94), Expect = 0.005
Identities = 35/113 (30%), Positives = 48/113 (42%), Gaps = 14/113 (12%)
Query: 564 PQDDKCGFPESVENG-----DFVHCEESGRRVLVYSCRHG--YELQGREQLTCTQEGWDF 616
P D +C E E+G + + +E R L+ CR G + +G + C G
Sbjct: 1090 PGDFECKCDEGYESGFMMMKNCMDIDECQRDPLL--CRGGVCHNTEGSYRCECPP-GHQL 1146
Query: 617 QPPL--CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
P + C D+NEC AH + RC N G +QC C Y D CVD
Sbjct: 1147 SPNISACIDINECELSAH--LCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVD 1197
Score = 40.4 bits (93), Expect = 0.006
Identities = 16/44 (36%), Positives = 25/44 (56%), Gaps = 2/44 (4%)
Query: 620 LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGR 663
+C+D++EC +G P C +A C NT G ++C C Y G+
Sbjct: 1805 VCEDIDECQNG--PVCQRNAECINTAGSYRCDCKPGYRFTSTGQ 1846
Score = 39.3 bits (90), Expect = 0.014
Identities = 20/48 (41%), Positives = 23/48 (47%), Gaps = 3/48 (6%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 668
C DVNEC D P S C NT G + C C +EL CVD+
Sbjct: 1485 CTDVNECLD---PTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDT 1529
Score = 38.5 bits (88), Expect = 0.023
Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Query: 620 LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
+ +D++EC + P +C NT G FQC C Y L +D R C D
Sbjct: 1603 ILEDIDECQE--LPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDD 1648
Score = 38.1 bits (87), Expect = 0.031
Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C+D++EC+ C + C N G F+C+C ++L DGR C D
Sbjct: 570 CEDMDECS--IRNMC-LNGMCINEDGSFKCICKPGFQLASDGRYCKD 613
Score = 38.1 bits (87), Expect = 0.031
Identities = 17/47 (36%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C+D++EC P + C NT+G F+C C L GR C+D
Sbjct: 908 CEDIDECE--VFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLD 952
Score = 38.1 bits (87), Expect = 0.031
Identities = 18/51 (35%), Positives = 23/51 (45%), Gaps = 3/51 (5%)
Query: 620 LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGR 670
+C DVNEC P C NT G + C+C Y + G C+D R
Sbjct: 1645 VCDDVNECET---PGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRR 1692
Score = 37.4 bits (85), Expect = 0.052
Identities = 18/53 (33%), Positives = 25/53 (47%), Gaps = 2/53 (3%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPR 673
C D NEC + P + +C +T G F CLC ++ DD C+D R
Sbjct: 1847 CNDRNECQE--IPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECER 1897
Score = 36.6 bits (83), Expect = 0.089
Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 1/47 (2%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C D NEC + C + C+NT G F C C + L G +C D
Sbjct: 2522 CIDNNECTSDINL-CGSKGICQNTPGSFTCECQRGFSLDQTGSSCED 2567
Score = 36.6 bits (83), Expect = 0.089
Identities = 17/36 (47%), Positives = 21/36 (58%), Gaps = 3/36 (8%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPY 656
C+D+NEC A PC S C NT+GG+ C C Y
Sbjct: 2646 CQDINECGS-AQAPC--SYGCSNTEGGYLCGCPPGY 2678
Score = 36.2 bits (82), Expect = 0.12
Identities = 18/66 (27%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 611 QEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTC--VDS 668
+EG+ C D++EC++ + + +C N GG++C C + DG+ C +D
Sbjct: 1392 KEGYTGDGFTCTDLDECSENLN--LCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDE 1449
Query: 669 GRLPRV 674
LP +
Sbjct: 1450 CSLPNI 1455
Score = 35.8 bits (81), Expect = 0.15
Identities = 17/47 (36%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C+DV+EC A P C NT G F+C C ++L + + C D
Sbjct: 244 CQDVDECQ--AIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCED 288
Score = 35.4 bits (80), Expect = 0.20
Identities = 17/47 (36%), Positives = 23/47 (48%), Gaps = 2/47 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C D+NEC + + +CRNT G F C C + D +TC D
Sbjct: 763 CVDINECV--LNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCED 807
Score = 35.4 bits (80), Expect = 0.20
Identities = 16/48 (33%), Positives = 23/48 (47%), Gaps = 2/48 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 668
C D NEC P + RC NT+G + C C D + + C+D+
Sbjct: 2289 CVDENECQ--TKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDN 2334
Score = 35.0 bits (79), Expect = 0.26
Identities = 27/93 (29%), Positives = 41/93 (44%), Gaps = 13/93 (13%)
Query: 579 DFVHCEESGRRVLVYSCRHG--YELQGREQLTCTQEGWDFQPP--LCKDVNECADGAHPP 634
D CE S + C +G L G+ Q C G+ P C D++EC+ +
Sbjct: 1155 DINECELSA-----HLCPNGRCVNLIGKYQCACNP-GYHSTPDRLFCVDIDECSI-MNGG 1207
Query: 635 CHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C C N++G ++C C + L D R+C D
Sbjct: 1208 CETF--CTNSEGSYECSCQPGFALMPDQRSCTD 1238
Score = 35.0 bits (79), Expect = 0.26
Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 3/47 (6%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C+D++EC+ P C N G F+C C YEL G C D
Sbjct: 1444 CEDIDECS---LPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTD 1487
Score = 34.7 bits (78), Expect = 0.34
Identities = 21/77 (27%), Positives = 36/77 (46%), Gaps = 7/77 (9%)
Query: 595 CRHGYELQGREQLTCT-QEGWDFQPPL--CKDVNECADGAHPPCHASARCRNTKGGFQCL 651
C +G CT +G+ ++P L C+D++EC PC + C+N+ G F C
Sbjct: 776 CDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESS---PC-INGVCKNSPGSFICE 831
Query: 652 CADPYELGDDGRTCVDS 668
C+ L C+++
Sbjct: 832 CSSESTLDPTKTICIET 848
Score = 34.7 bits (78), Expect = 0.34
Identities = 25/75 (33%), Positives = 33/75 (44%), Gaps = 18/75 (24%)
Query: 594 SCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCA 653
SC GY LQ ++G CKD++ECA H + C NT GGF C C
Sbjct: 2469 SCPKGYILQ--------EDGRS-----CKDLDECATKQH---NCQFLCVNTIGGFTCKC- 2511
Query: 654 DPYELGDDGRTCVDS 668
P +C+D+
Sbjct: 2512 -PPGFTQHHTSCIDN 2525
Score = 34.7 bits (78), Expect = 0.34
Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 7/88 (7%)
Query: 583 CEESGRRVLVYSCRHGYE-LQGREQLTCTQEGW--DFQPPLCKDVNECADGAHPPCHASA 639
CE+ + C+HG + + G + +C Q G+ +Q C D NEC AH A
Sbjct: 2565 CEDVDECEGNHRCQHGCQNIIGGYRCSCPQ-GYLQHYQWNQCVDENECLS-AH--ICGGA 2620
Query: 640 RCRNTKGGFQCLCADPYELGDDGRTCVD 667
C NT G ++C+C ++ C D
Sbjct: 2621 SCHNTLGSYKCMCPAGFQYEQFSGGCQD 2648
Score = 34.3 bits (77), Expect = 0.44
Identities = 23/84 (27%), Positives = 35/84 (41%), Gaps = 13/84 (15%)
Query: 595 CRHGYELQGREQLTCT--------QEGWD---FQPPLCKDVNECADGAHPPCHASARCRN 643
CR +L GR Q T EG++ C D++EC P C N
Sbjct: 1074 CRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQ--RDPLLCRGGVCHN 1131
Query: 644 TKGGFQCLCADPYELGDDGRTCVD 667
T+G ++C C ++L + C+D
Sbjct: 1132 TEGSYRCECPPGHQLSPNISACID 1155
Score = 33.5 bits (75), Expect = 0.75
Identities = 14/47 (29%), Positives = 21/47 (44%), Gaps = 2/47 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C+D++EC+ P C NT + C C + DG C+D
Sbjct: 286 CEDIDECS--TIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCID 330
Score = 33.5 bits (75), Expect = 0.75
Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 5/48 (10%)
Query: 620 LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
+C D+NEC A C + CRNT G F C C + L + C+D
Sbjct: 1888 MCLDINECERDA---C-GNGTCRNTIGSFNCRCNHGFILSHN-NDCID 1930
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 52.4 bits (124), Expect = 2e-06
Identities = 50/168 (29%), Positives = 70/168 (41%), Gaps = 16/168 (9%)
Query: 512 ELEKHSLSRVICDNT--GLTRVPMDAFQVGKFPE--DFESCDSITGM---NLEAWRETFP 564
E E+H C NT + F++ + D + C S G N + E
Sbjct: 1937 ECERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEI-- 1994
Query: 565 QDDKCGFPESVE-NGDFVHCEESGRRV-LVYSCRHG--YELQGREQLTCTQEGWDFQPPL 620
KC E E D +C ++ V L SC G L+G + C G++ +
Sbjct: 1995 GSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPP-GYEVKSEN 2053
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 668
C D+NEC + P C NT GGFQCLC + L D+GR C D+
Sbjct: 2054 CIDINECDED--PNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDT 2099
Score = 49.7 bits (117), Expect = 1e-05
Identities = 39/151 (25%), Positives = 61/151 (40%), Gaps = 24/151 (15%)
Query: 524 DNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHC 583
D TG+ V D +G P +C ++ G +C E E G ++C
Sbjct: 2205 DYTGVRCVDTDECSIGN-PCGNGTCTNVIG------------SFECNCNEGFEPGPMMNC 2251
Query: 584 EESGR-----RVLVYSCRHGYELQGREQLTCTQEGWDFQPP--LCKDVNECADGAHPPCH 636
E+ + + C + + G + TC G+ + +CKD++ECA+G H
Sbjct: 2252 EDINECAQNPLLCAFRCMNTF---GSYECTCPI-GYALREDQKMCKDLDECAEGLHDCES 2307
Query: 637 ASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C+N G F C+C DG CVD
Sbjct: 2308 RGMMCKNLIGTFMCICPPGMARRPDGEGCVD 2338
Score = 48.5 bits (114), Expect = 2e-05
Identities = 24/67 (35%), Positives = 39/67 (58%), Gaps = 4/67 (5%)
Query: 601 LQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGD 660
+ G + +C +EGW C D++EC++G H C +A+C NT G ++C C++ +
Sbjct: 1387 IPGSFKCSC-REGWIGNGIKCIDLDECSNGTHQ-CSINAQCVNTPGSYRCACSEGFT--G 1442
Query: 661 DGRTCVD 667
DG TC D
Sbjct: 1443 DGFTCSD 1449
Score = 46.6 bits (109), Expect = 9e-05
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 3/75 (4%)
Query: 615 DFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRV 674
D C D++EC+ P + C+NT+G +QC C Y L +DG+TC D
Sbjct: 2483 DISGTSCIDLDECSQSPKP---CNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTK 2539
Query: 675 TWISMSLAALLIGGF 689
L +GGF
Sbjct: 2540 QHNCQFLCVNTLGGF 2554
Score = 44.7 bits (104), Expect = 3e-04
Identities = 20/47 (42%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C D++EC + RC NT G FQC+C +EL DG+ CVD
Sbjct: 573 CIDIDECIQNG--VLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVD 617
Score = 44.7 bits (104), Expect = 3e-04
Identities = 34/123 (27%), Positives = 55/123 (44%), Gaps = 25/123 (20%)
Query: 548 CDSITGMNLEAWRETFPQDDKCGFPESV-ENGDFVHCEESGRRVLVYSCRHGYELQGREQ 606
CD G L RE ++C +++ NG V+ + + SC GY Q
Sbjct: 1183 CDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQ----CSCNPGY------Q 1232
Query: 607 LTCTQEGWDFQPPLCKDVNECA--DGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRT 664
T ++G C D++EC +G +C N++G ++C C++ Y L DGR+
Sbjct: 1233 ATPDRQG-------CTDIDECMIMNGG-----CDTQCTNSEGSYECSCSEGYALMPDGRS 1280
Query: 665 CVD 667
C D
Sbjct: 1281 CAD 1283
Score = 43.5 bits (101), Expect = 7e-04
Identities = 20/47 (42%), Positives = 25/47 (53%), Gaps = 2/47 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C+DVNEC P + RC N+KG F C C + L GR C+D
Sbjct: 953 CEDVNECE--VFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLD 997
Score = 43.1 bits (100), Expect = 0.001
Identities = 21/59 (35%), Positives = 30/59 (50%), Gaps = 6/59 (10%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRVTWISM 679
C+D+NEC PC + CRN G F C C+ +L G C+DS L W+++
Sbjct: 850 CEDINECESN---PC-VNGACRNNLGSFNCECSPGSKLSSTGLICIDS--LKGTCWLNI 902
Score = 42.4 bits (98), Expect = 0.002
Identities = 20/49 (40%), Positives = 25/49 (51%), Gaps = 2/49 (4%)
Query: 619 PLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
P KD+NEC A P +CRNT G F+C C + L + R C D
Sbjct: 1069 PFYKDINECK--AFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTD 1115
Score = 42.0 bits (97), Expect = 0.002
Identities = 21/68 (30%), Positives = 36/68 (52%), Gaps = 5/68 (7%)
Query: 602 QGREQLTCTQEGWDFQPP--LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELG 659
+G + +C+ EG+ P C D++EC + +P +C N G ++CLC D +
Sbjct: 1261 EGSYECSCS-EGYALMPDGRSCADIDECEN--NPDICDGGQCTNIPGEYRCLCYDGFMAS 1317
Query: 660 DDGRTCVD 667
D +TC+D
Sbjct: 1318 MDMKTCID 1325
Score = 41.6 bits (96), Expect = 0.003
Identities = 18/46 (39%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
Query: 622 KDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
+D+NECA P A+ C N +G ++C C YE GR C+D
Sbjct: 767 RDINECA--LDPDICANGICENLRGSYRCNCNSGYEPDASGRNCID 810
Score = 41.6 bits (96), Expect = 0.003
Identities = 18/48 (37%), Positives = 32/48 (66%), Gaps = 2/48 (4%)
Query: 620 LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
+C+D++EC++G + C +A C N+ G ++C CA ++L +G CVD
Sbjct: 1847 VCEDIDECSNGDNL-CQRNADCINSPGSYRCECAAGFKLSPNG-ACVD 1892
Score = 41.2 bits (95), Expect = 0.004
Identities = 17/48 (35%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Query: 620 LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
+C+D++EC AHP C NT G + C+C Y + G C+D
Sbjct: 1689 ICEDIDECF--AHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMD 1734
Score = 40.8 bits (94), Expect = 0.005
Identities = 19/48 (39%), Positives = 26/48 (54%), Gaps = 3/48 (6%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 668
C DV+EC P + C N++G F+C C +G DGR CVD+
Sbjct: 656 CTDVDECQT---PGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDT 700
Score = 39.3 bits (90), Expect = 0.014
Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 3/48 (6%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 668
C D++ECAD P + C NT G ++C C ++L G CVD+
Sbjct: 1530 CTDIDECAD---PINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDN 1574
Score = 38.9 bits (89), Expect = 0.018
Identities = 19/47 (40%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Query: 622 KDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 668
+DVNEC + P ++ +C NT G F+C C Y L G CVD+
Sbjct: 2170 EDVNECLES--PGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDT 2214
Score = 38.5 bits (88), Expect = 0.023
Identities = 20/47 (42%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C DV+EC GAH C A C N G F+C C + + +G +G C+D
Sbjct: 1365 CTDVDECEIGAHN-CDMHASCLNIPGSFKCSCREGW-IG-NGIKCID 1408
Score = 38.5 bits (88), Expect = 0.023
Identities = 23/67 (34%), Positives = 30/67 (44%), Gaps = 6/67 (8%)
Query: 605 EQLTCTQEGWDFQPP----LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGD 660
E T G F+P + +D++EC + P C NT G FQC C Y L +
Sbjct: 1628 EYYTLCPGGEGFRPNPITIILEDIDECQE--LPGLCQGGNCINTFGSFQCECPQGYYLSE 1685
Query: 661 DGRTCVD 667
D R C D
Sbjct: 1686 DTRICED 1692
Score = 38.5 bits (88), Expect = 0.023
Identities = 26/90 (28%), Positives = 41/90 (45%), Gaps = 7/90 (7%)
Query: 581 VHCEESGRRVLVYSCRHGYE-LQGREQLTCTQEGW--DFQPPLCKDVNECADGAHPPCHA 637
++CE+ + C+HG + + G + C Q G+ +Q C D NEC++ P
Sbjct: 2610 LNCEDVDECDGNHRCQHGCQNILGGYRCGCPQ-GYIQHYQWNQCVDENECSN---PNACG 2665
Query: 638 SARCRNTKGGFQCLCADPYELGDDGRTCVD 667
SA C NT G ++C C + C D
Sbjct: 2666 SASCYNTLGSYKCACPSGFSFDQFSSACHD 2695
Score = 38.1 bits (87), Expect = 0.031
Identities = 16/47 (34%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C+D++EC+ P + C NT G + C+C Y DG C+D
Sbjct: 316 CEDIDECS--IIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCID 360
Score = 38.1 bits (87), Expect = 0.031
Identities = 20/48 (41%), Positives = 23/48 (47%), Gaps = 3/48 (6%)
Query: 621 CKDVNECADGAHPP-CHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C D NEC G+ P C A C+NT G F C C + L G C D
Sbjct: 2569 CIDNNEC--GSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCED 2614
Score = 37.4 bits (85), Expect = 0.052
Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 3/47 (6%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C+D++EC+ C N G F C+C D YEL G C D
Sbjct: 1489 CQDIDECS---FQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTD 1532
Score = 37.0 bits (84), Expect = 0.068
Identities = 18/47 (38%), Positives = 23/47 (48%), Gaps = 2/47 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C D++EC +P C NT+G FQC C +EL CVD
Sbjct: 1156 CMDIDECE--RNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVD 1200
Score = 36.6 bits (83), Expect = 0.089
Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 9/94 (9%)
Query: 568 KCGFPES-VENGDFVHCEESGRRVLVYSCRHG--YELQGREQLTCTQEGWDFQP--PLCK 622
+CG P+ +++ + C + +C Y G + C G+ F C
Sbjct: 2636 RCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPS-GFSFDQFSSACH 2694
Query: 623 DVNECADGAHPPCHASARCRNTKGGFQCLCADPY 656
DVNEC+ +P + C NT+GG+ C C Y
Sbjct: 2695 DVNECSSSKNP---CNYGCSNTEGGYLCGCPPGY 2725
Score = 35.8 bits (81), Expect = 0.15
Identities = 20/65 (30%), Positives = 32/65 (49%), Gaps = 3/65 (4%)
Query: 603 GREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDG 662
G + C+ EG+ C DV+ECA+ + C + +C N G ++C C + D
Sbjct: 1430 GSYRCACS-EGFTGDGFTCSDVDECAENINL-CE-NGQCLNVPGAYRCECEMGFTPASDS 1486
Query: 663 RTCVD 667
R+C D
Sbjct: 1487 RSCQD 1491
Score = 35.4 bits (80), Expect = 0.20
Identities = 17/45 (37%), Positives = 22/45 (48%), Gaps = 2/45 (4%)
Query: 615 DFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELG 659
D + C D++EC P S C NT G F+C C + YE G
Sbjct: 1107 DMEERNCTDIDECR--ISPDLCGSGICVNTPGSFECECFEGYESG 1149
Score = 35.0 bits (79), Expect = 0.26
Identities = 15/46 (32%), Positives = 23/46 (50%), Gaps = 2/46 (4%)
Query: 622 KDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
+D++EC P + +C NT G F+C C Y G +C+D
Sbjct: 2448 RDIDECK--VMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCID 2491
Score = 33.9 bits (76), Expect = 0.58
Identities = 24/75 (32%), Positives = 31/75 (41%), Gaps = 18/75 (24%)
Query: 594 SCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCA 653
SC GY LQ ++G CKD++EC H + C NT GGF C C
Sbjct: 2516 SCPRGYVLQ--------EDG-----KTCKDLDECQTKQH---NCQFLCVNTLGGFTCKC- 2558
Query: 654 DPYELGDDGRTCVDS 668
P C+D+
Sbjct: 2559 -PPGFTQHHTACIDN 2572
Score = 33.5 bits (75), Expect = 0.75
Identities = 16/47 (34%), Positives = 23/47 (48%), Gaps = 2/47 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C+DV+EC A P C NT G F+C C ++ + + C D
Sbjct: 274 CQDVDECQ--AIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCED 318
Score = 32.7 bits (73), Expect = 1.3
Identities = 15/47 (31%), Positives = 20/47 (42%), Gaps = 9/47 (19%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C N C +G C N G F+C+C + L +GR C D
Sbjct: 621 CTTTNMCLNGM---------CINEDGSFKCICKPGFVLAPNGRYCTD 658
Score = 32.7 bits (73), Expect = 1.3
Identities = 14/47 (29%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C D NEC + + H C + +G +QC+C + ++ D C+D
Sbjct: 1890 CVDRNECLEIPNVCSHGL--CVDLQGSYQCICHNGFKASQDQTMCMD 1934
Score = 32.0 bits (71), Expect = 2.2
Identities = 15/47 (31%), Positives = 21/47 (44%), Gaps = 2/47 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C D++EC + + CRNT G + C C Y + TC D
Sbjct: 808 CIDIDECL--VNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCED 852
Score = 31.6 bits (70), Expect = 2.9
Identities = 15/47 (31%), Positives = 22/47 (46%), Gaps = 4/47 (8%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C DV+EC PC + C NT G + C C ++ + C+D
Sbjct: 533 CIDVDECTSN---PC-TNGDCVNTPGSYYCKCHAGFQRTPTKQACID 575
Score = 30.8 bits (68), Expect = 4.9
Identities = 17/47 (36%), Positives = 20/47 (42%), Gaps = 2/47 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C DVNEC ++ C NTKG F C C Y + C D
Sbjct: 1323 CIDVNECDLNSN--ICMFGECENTKGSFICHCQLGYSVKKGTTGCTD 1367
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 52.4 bits (124), Expect = 2e-06
Identities = 30/82 (36%), Positives = 40/82 (48%), Gaps = 6/82 (7%)
Query: 589 RVLVYSCRHGYELQGREQLTC-TQEGW--DFQPPLCKDVNECADGAHPPCHASARCRNTK 645
R+L + C HG + C Q G+ D C D++EC+ P + C+NTK
Sbjct: 2368 RMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKP---CTFLCKNTK 2424
Query: 646 GGFQCLCADPYELGDDGRTCVD 667
G F C C Y L +DGRTC D
Sbjct: 2425 GSFLCSCPRGYLLEEDGRTCKD 2446
Score = 48.5 bits (114), Expect = 2e-05
Identities = 30/77 (38%), Positives = 37/77 (48%), Gaps = 7/77 (9%)
Query: 595 CRHG--YELQGREQLTCTQEGWDFQPP--LCKDVNECADGAHPPCHASARCRNTKGGFQC 650
C HG + G C G+ P C DV+EC CH RC NT+G FQC
Sbjct: 458 CHHGDCVNIPGTYHCRC-YPGFQATPTRQACVDVDECIVSGGL-CHLG-RCVNTEGSFQC 514
Query: 651 LCADPYELGDDGRTCVD 667
+C +EL DG+ CVD
Sbjct: 515 VCNAGFELSPDGKNCVD 531
Score = 47.4 bits (111), Expect = 5e-05
Identities = 29/77 (37%), Positives = 39/77 (50%), Gaps = 4/77 (5%)
Query: 583 CEESGRRVLVYSCRHGYELQ-GREQLTCTQEGWDF-QPPLCKDVNECADGAHPPCHASAR 640
CE+ + C+HG + Q G + +C Q Q C D NECA PP SA
Sbjct: 2526 CEDVNECDGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECA--LSPPTCGSAS 2583
Query: 641 CRNTKGGFQCLCADPYE 657
CRNT GGF+C+C ++
Sbjct: 2584 CRNTLGGFRCVCPSGFD 2600
Score = 46.2 bits (108), Expect = 1e-04
Identities = 21/48 (43%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 668
C D +EC C C NT G F CLC D +EL DG+ CVD+
Sbjct: 1884 CVDFDECTTLVGQVCRFG-HCLNTAGSFHCLCQDGFELTADGKNCVDT 1930
Score = 45.8 bits (107), Expect = 1e-04
Identities = 26/73 (35%), Positives = 35/73 (47%), Gaps = 5/73 (6%)
Query: 597 HGYELQGREQLTCTQEGWDFQPP--LCKDVNECADGAHPPCHASARCRNTKGGFQCLCAD 654
H +G + +C Q G+ P C DV+EC + +P C N GG +CLC D
Sbjct: 1169 HCINTEGSYRCSCGQ-GYSLMPDGRACADVDECEE--NPRVCDQGHCTNMPGGHRCLCYD 1225
Query: 655 PYELGDDGRTCVD 667
+ D RTCVD
Sbjct: 1226 GFMATPDMRTCVD 1238
Score = 45.8 bits (107), Expect = 1e-04
Identities = 37/135 (27%), Positives = 56/135 (41%), Gaps = 18/135 (13%)
Query: 544 DFESCDSITG--------MNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSC 595
DF+ C ++ G +N QD GF + + + V E L +C
Sbjct: 1886 DFDECTTLVGQVCRFGHCLNTAGSFHCLCQD---GFELTADGKNCVDTNEC--LSLAGTC 1940
Query: 596 RHG--YELQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCA 653
G L+G + C G+ Q C D++EC++ P C N+ G FQCLC
Sbjct: 1941 LPGTCQNLEGSFRCICPP-GFQVQSDHCIDIDECSE--EPNLCLFGTCTNSPGSFQCLCP 1997
Query: 654 DPYELGDDGRTCVDS 668
+ L D+G C D+
Sbjct: 1998 PGFVLSDNGHRCFDT 2012
Score = 44.7 bits (104), Expect = 3e-04
Identities = 19/48 (39%), Positives = 26/48 (54%), Gaps = 3/48 (6%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 668
C D++EC P + C NT+G F+C C +G DGR CVD+
Sbjct: 570 CMDIDECQT---PGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDT 614
Score = 43.1 bits (100), Expect = 0.001
Identities = 21/47 (44%), Positives = 25/47 (53%), Gaps = 2/47 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C DVNEC + P + RC NT G F+C C + L GR CVD
Sbjct: 867 CDDVNECE--SFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVD 911
Score = 42.7 bits (99), Expect = 0.001
Identities = 21/55 (38%), Positives = 30/55 (54%), Gaps = 6/55 (10%)
Query: 616 FQPPL---CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
F+P L C+D++EC+ P + RC NT+G + C C Y L +DG C D
Sbjct: 2156 FEPGLMMTCEDIDECSLN---PLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRD 2207
Score = 42.4 bits (98), Expect = 0.002
Identities = 18/46 (39%), Positives = 26/46 (56%), Gaps = 2/46 (4%)
Query: 622 KDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
+D+NECA P A+ C N +G ++C+C YE G G+ C D
Sbjct: 681 RDINECA--LDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTD 724
Score = 42.4 bits (98), Expect = 0.002
Identities = 21/49 (42%), Positives = 22/49 (44%), Gaps = 2/49 (4%)
Query: 619 PLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
P KDVNEC P CRNT G F C CA + L R C D
Sbjct: 982 PFYKDVNECK--VFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTD 1028
Score = 42.4 bits (98), Expect = 0.002
Identities = 20/48 (41%), Positives = 25/48 (52%), Gaps = 3/48 (6%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 668
C D+NECAD P + C NT G + C C +EL G CVD+
Sbjct: 1443 CTDINECAD---PVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDT 1487
Score = 42.0 bits (97), Expect = 0.002
Identities = 27/79 (34%), Positives = 35/79 (44%), Gaps = 12/79 (15%)
Query: 595 CRHGY--ELQGREQLTCTQEGWDFQPPL--CKDVNECA--DGAHPPCHASARCRNTKGGF 648
C HG + G Q +C G+ P C D+NEC +G C NT+G +
Sbjct: 1124 CPHGQCVNVIGAFQCSC-HAGFQSTPDRQGCVDINECRVQNGG-----CDVHCINTEGSY 1177
Query: 649 QCLCADPYELGDDGRTCVD 667
+C C Y L DGR C D
Sbjct: 1178 RCSCGQGYSLMPDGRACAD 1196
Score = 41.6 bits (96), Expect = 0.003
Identities = 42/153 (27%), Positives = 60/153 (39%), Gaps = 27/153 (17%)
Query: 524 DNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHC 583
D TG+ V D VG P +C ++ G +C + E G + C
Sbjct: 2118 DFTGINCVDTDECSVGH-PCGQGTCTNVIG------------GFECACADGFEPGLMMTC 2164
Query: 584 EESGRRVL-----VYSCRHGYELQGREQLTCTQEGWDFQPP--LCKDVNECADGAHPPCH 636
E+ L + C + +G TC G+ + +C+DV+ECADG CH
Sbjct: 2165 EDIDECSLNPLLCAFRC---HNTEGSYLCTCPA-GYTLREDGAMCRDVDECADG-QQDCH 2219
Query: 637 A-SARCRNTKGGFQCLCADPYE-LGDDGRTCVD 667
A C+N G F C+C L G C D
Sbjct: 2220 ARGMECKNLIGTFACVCPPGMRPLPGSGEGCTD 2252
Score = 41.2 bits (95), Expect = 0.004
Identities = 20/47 (42%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C+DV+ECA G A C N G F+C+C YEL G C D
Sbjct: 1402 CQDVDECAQGN---LCAFGSCENLPGMFRCICNGGYELDRGGGNCTD 1445
Score = 40.8 bits (94), Expect = 0.005
Identities = 24/68 (35%), Positives = 31/68 (45%), Gaps = 2/68 (2%)
Query: 622 KDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRVTWISMSL 681
+DVNECA+ +P + C NT G F+C C Y L G CVD+
Sbjct: 2083 EDVNECAE--NPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGT 2140
Query: 682 AALLIGGF 689
+IGGF
Sbjct: 2141 CTNVIGGF 2148
Score = 40.4 bits (93), Expect = 0.006
Identities = 20/49 (40%), Positives = 24/49 (48%), Gaps = 4/49 (8%)
Query: 620 LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 668
+CKDV+EC PC S CRN G + C C L G C+DS
Sbjct: 763 ICKDVDECLSS---PC-VSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDS 807
Score = 39.7 bits (91), Expect = 0.011
Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 7/100 (7%)
Query: 570 GFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCT-QEGWDFQPPL--CKDVNE 626
GF + G + +E G + C +G + C G+++ L C+DV+E
Sbjct: 1709 GFLTDIHTGKPLDIDECGEIPAI--CANGICINQIGSFRCECPAGFNYNSILLACEDVDE 1766
Query: 627 CADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCV 666
C PC +A C N G ++C C Y+L G CV
Sbjct: 1767 CGS-RESPCQQNADCINIPGSYRCKCTRGYKLSPGG-ACV 1804
Score = 39.7 bits (91), Expect = 0.011
Identities = 20/48 (41%), Positives = 24/48 (50%), Gaps = 3/48 (6%)
Query: 621 CKDVNECADGAHP-PCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C D +EC+ A P PC A C NT G F+C C + L G C D
Sbjct: 2483 CFDNDECS--AQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCED 2528
Score = 39.7 bits (91), Expect = 0.011
Identities = 25/56 (44%), Positives = 29/56 (51%), Gaps = 6/56 (10%)
Query: 613 GWDFQPPL--CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCV 666
G+DF L C++V+ECA G PC S C NT GGF C C Y G CV
Sbjct: 2598 GFDFDQALGGCQEVDECA-GRRGPCSYS--CANTPGGFLCGCPQGYFRAGQGH-CV 2649
Score = 38.5 bits (88), Expect = 0.023
Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 4/47 (8%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C+DVNEC DG H H C+N GG++C C + CVD
Sbjct: 2526 CEDVNEC-DGPHRCQHG---CQNQLGGYRCSCPQGFTQHSQWAQCVD 2568
Score = 38.1 bits (87), Expect = 0.031
Identities = 30/98 (30%), Positives = 39/98 (39%), Gaps = 8/98 (8%)
Query: 572 PESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPL--CKDVNECAD 629
P+ D CEE+ R V H + G + C +G+ P + C DV+EC
Sbjct: 1189 PDGRACADVDECEENPR---VCDQGHCTNMPGGHRCLC-YDGFMATPDMRTCVDVDECDL 1244
Query: 630 GAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
H H C NTKG F C C Y + C D
Sbjct: 1245 NPHICLHGD--CENTKGSFVCHCQLGYMVRKGATGCSD 1280
Score = 37.4 bits (85), Expect = 0.052
Identities = 33/133 (24%), Positives = 49/133 (36%), Gaps = 27/133 (20%)
Query: 537 QVGKFPEDFESCDSITGMNLEAWRETFPQDDKCGFPESV--ENGDFVHCEESGRRVLVYS 594
Q+G F C+ G N + D+CG ES +N D ++ S R
Sbjct: 1740 QIGSF-----RCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYR----CK 1790
Query: 595 CRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCAD 654
C GY+L C NEC + + H C +T+G + CLC
Sbjct: 1791 CTRGYKLS--------------PGGACVGRNECREIPNVCSHGD--CMDTEGSYMCLCHR 1834
Query: 655 PYELGDDGRTCVD 667
++ D C+D
Sbjct: 1835 GFQASADQTLCMD 1847
Score = 37.0 bits (84), Expect = 0.068
Identities = 18/47 (38%), Positives = 22/47 (46%), Gaps = 2/47 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C DV+ECA P C NT G ++C C +EL G C D
Sbjct: 1069 CMDVDECA--RDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACED 1113
Score = 36.6 bits (83), Expect = 0.089
Identities = 21/47 (44%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C DV+EC G H C + A C N G F C C P +G DG C D
Sbjct: 1278 CSDVDECEVGGHN-CDSHASCLNIPGSFSCRCL-PGWVG-DGFECHD 1321
Score = 36.6 bits (83), Expect = 0.089
Identities = 23/67 (34%), Positives = 29/67 (43%), Gaps = 6/67 (8%)
Query: 605 EQLTCTQEGWDFQPP----LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGD 660
E T G FQP + +D++EC + P C NT G FQC C Y L +
Sbjct: 1541 EYRTLCPGGEGFQPNRITVILEDIDECQE--LPGLCQGGDCVNTFGSFQCECPPGYHLSE 1598
Query: 661 DGRTCVD 667
R C D
Sbjct: 1599 HTRICED 1605
Score = 36.6 bits (83), Expect = 0.089
Identities = 15/48 (31%), Positives = 24/48 (50%), Gaps = 2/48 (4%)
Query: 620 LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
+C+D++EC+ H C NT G + C+C Y + G C+D
Sbjct: 1602 ICEDIDECS--THSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMD 1647
Score = 36.2 bits (82), Expect = 0.12
Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 3/65 (4%)
Query: 603 GREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDG 662
G + TC Q G+ C+D +ECA+ C + +C N GG++C C ++ +D
Sbjct: 1343 GSYRCTCRQ-GFAGDGFFCEDRDECAENVDL-CD-NGQCLNAPGGYRCECEMGFDPTEDH 1399
Query: 663 RTCVD 667
R C D
Sbjct: 1400 RACQD 1404
Score = 35.0 bits (79), Expect = 0.26
Identities = 23/68 (33%), Positives = 29/68 (42%), Gaps = 6/68 (8%)
Query: 602 QGREQLTCTQEGWDFQPP--LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELG 659
+G Q C G++ P C D NECA C + C N G F CLC + L
Sbjct: 509 EGSFQCVCNA-GFELSPDGKNCVDHNECATSTM--C-VNGVCLNEDGSFSCLCKPGFLLA 564
Query: 660 DDGRTCVD 667
G C+D
Sbjct: 565 PGGHYCMD 572
Score = 35.0 bits (79), Expect = 0.26
Identities = 21/78 (26%), Positives = 31/78 (39%), Gaps = 2/78 (2%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRVTWISMS 680
C D NEC A P + RC NT G F+C C + ++ C D + P + +
Sbjct: 2250 CTDDNECH--AQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQT 2307
Query: 681 LAALLIGGFAGLTSTVIC 698
+ L +T C
Sbjct: 2308 MCRSLSSSSEAVTRAECC 2325
Score = 33.9 bits (76), Expect = 0.58
Identities = 17/47 (36%), Positives = 20/47 (42%), Gaps = 2/47 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C+DV+EC A P C N G F C C + L D C D
Sbjct: 245 CQDVDECQ--AVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
Score = 33.9 bits (76), Expect = 0.58
Identities = 17/45 (37%), Positives = 20/45 (44%), Gaps = 2/45 (4%)
Query: 615 DFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELG 659
D Q C D++EC P C NT G F+C C YE G
Sbjct: 1020 DAQERNCTDIDECR--ISPDLCGQGTCVNTPGSFECECFPGYESG 1062
Score = 33.1 bits (74), Expect = 0.99
Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 2/53 (3%)
Query: 622 KDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRV 674
+DV+EC AH H C N+ G F+C C Y TC+D +V
Sbjct: 2362 RDVDECRMLAHLCAHGE--CINSLGSFRCHCQAGYTPDATATTCLDMDECSQV 2412
Score = 32.3 bits (72), Expect = 1.7
Identities = 17/55 (30%), Positives = 22/55 (40%), Gaps = 3/55 (5%)
Query: 613 GWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
GW C D++EC H C C N G ++C C + DG C D
Sbjct: 1311 GWVGDGFECHDLDECVSQEHR-CSPRGDCLNVPGSYRCTCRQGF--AGDGFFCED 1362
Score = 30.0 bits (66), Expect = 8.3
Identities = 14/47 (29%), Positives = 21/47 (44%), Gaps = 2/47 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C DV+ECA + + C+N+ G + C C + D C D
Sbjct: 722 CTDVDECA--LNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKD 766
Score = 30.0 bits (66), Expect = 8.3
Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 3/32 (9%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLC 652
CKD++EC H + C NT G F C C
Sbjct: 2444 CKDLDECTSRQH---NCQFLCVNTVGAFTCRC 2472
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 52.4 bits (124), Expect = 2e-06
Identities = 32/94 (34%), Positives = 43/94 (45%), Gaps = 16/94 (17%)
Query: 572 PESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGA 631
P + NG +H + R + C GY+L + C+DV+ECA G
Sbjct: 247 PCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKA-------------CEDVDECAAGL 293
Query: 632 HPPCHASARCRNTKGGFQCLCADPYELGDDGRTC 665
H C NT+G F+C+C YELG DGR C
Sbjct: 294 AQCAHG---CLNTQGSFKCVCHAGYELGADGRQC 324
Score = 42.4 bits (98), Expect = 0.002
Identities = 26/75 (34%), Positives = 31/75 (41%), Gaps = 6/75 (8%)
Query: 595 CRHGYELQGREQLTCTQEGW--DFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLC 652
C HG L G+ D C DV++CAD PC C N GG++C C
Sbjct: 342 CSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADS---PCCQQV-CTNNPGGYECGC 397
Query: 653 ADPYELGDDGRTCVD 667
Y L DG C D
Sbjct: 398 YAGYRLSADGCGCED 412
Score = 39.3 bits (90), Expect = 0.014
Identities = 32/120 (26%), Positives = 39/120 (32%), Gaps = 37/120 (30%)
Query: 583 CEESGRRVLVY-SCRHGYELQGREQLTCTQEGWDFQPP------------LCKDVNECAD 629
C RR + Y R Y + R L C + GW QP LC C
Sbjct: 83 CVGHERRTVYYMGYRQVYTTEARTVLRCCR-GWMQQPDEEGCLSAECSASLCFHGGRCVP 141
Query: 630 GAHPPCHASA-----------------------RCRNTKGGFQCLCADPYELGDDGRTCV 666
G+ PCH RC NT G + C C + L D RTC+
Sbjct: 142 GSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCL 201
Score = 38.5 bits (88), Expect = 0.023
Identities = 19/45 (42%), Positives = 22/45 (48%), Gaps = 3/45 (6%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTC 665
C+DV+ECA H C N G FQC C Y L +D R C
Sbjct: 410 CEDVDECASSRGGCEH---HCTNLAGSFQCSCEAGYRLHEDRRGC 451
Score = 34.3 bits (77), Expect = 0.44
Identities = 24/73 (32%), Positives = 29/73 (39%), Gaps = 11/73 (15%)
Query: 595 CRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCAD 654
C GYEL G + C + + VN C H C +T G C C
Sbjct: 311 CHAGYEL-GADGRQCYRIEMEI-------VNSCEANNGGCSHG---CSHTSAGPLCTCPR 359
Query: 655 PYELGDDGRTCVD 667
YEL D RTC+D
Sbjct: 360 GYELDTDQRTCID 372
>gi|157384998 low density lipoprotein receptor-related protein 4
[Homo sapiens]
Length = 1905
Score = 51.2 bits (121), Expect = 3e-06
Identities = 44/160 (27%), Positives = 67/160 (41%), Gaps = 33/160 (20%)
Query: 523 CDNTGLTRVPMDAFQV--GKFPEDFESCDSITGMNLEAWRETFPQ--------DDKCGFP 572
C+NTG + +D F G+ + C+ + + + PQ ++ C
Sbjct: 304 CENTGSPQCALDQFLCWNGRCIGQRKLCNGVNDCGDNS--DESPQQNCRPRTGEENC--- 358
Query: 573 ESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAH 632
+V NG + R + +C GY L T++G C+DVNECA+ +
Sbjct: 359 -NVNNGGCAQKCQMVRGAVQCTCHTGYRL--------TEDGHT-----CQDVNECAEEGY 404
Query: 633 PPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLP 672
S C N++G FQC C YEL D R+C G P
Sbjct: 405 ----CSQGCTNSEGAFQCWCETGYELRPDRRSCKALGPEP 440
>gi|122937283 6720455I24Rik homolog [Homo sapiens]
Length = 1413
Score = 51.2 bits (121), Expect = 3e-06
Identities = 27/90 (30%), Positives = 41/90 (45%), Gaps = 4/90 (4%)
Query: 569 CGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQL-TCTQEGWDFQPPLCKDVNEC 627
CG PE V++ V +Y+C GY L ++ C G +PP C +++EC
Sbjct: 698 CGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDEC 757
Query: 628 ADGAHPPCHASARCRNTKGGFQCLCADPYE 657
PC C++ G+ CLC+ YE
Sbjct: 758 RS---QPCLHGGSCQDRVAGYLCLCSTGYE 784
Score = 35.0 bits (79), Expect = 0.26
Identities = 31/108 (28%), Positives = 45/108 (41%), Gaps = 28/108 (25%)
Query: 583 CEESGRRVLVYSCRHGYELQ---GREQLTCTQEGWDFQPPLCK-DVNECADGAHPPCHAS 638
CE + C+HG + Q G C Q G + C+ DV++C+ PC
Sbjct: 346 CETAQSPCDTKECQHGGQCQVENGSAVCVC-QAG--YTGAACEMDVDDCSPD---PCLNG 399
Query: 639 ARCRNTKGGFQCLCADPY-----ELGD-------------DGRTCVDS 668
C + G + CLCA+P+ E GD +G TCVD+
Sbjct: 400 GSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDA 447
>gi|110347437 latent transforming growth factor beta binding protein
4 isoform c [Homo sapiens]
Length = 1557
Score = 50.8 bits (120), Expect = 5e-06
Identities = 38/126 (30%), Positives = 48/126 (38%), Gaps = 18/126 (14%)
Query: 542 PEDFESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYEL 601
P F+ +G +L R T + G P +G + E S R SC GY
Sbjct: 746 PGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFR----CSCAPGYRA 801
Query: 602 QGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDD 661
+P C DVNEC +G C C NT G F C CA Y G
Sbjct: 802 PSG------------RPGPCADVNECLEGDF--CFPHGECLNTDGSFACTCAPGYRPGPR 847
Query: 662 GRTCVD 667
G +C+D
Sbjct: 848 GASCLD 853
Score = 50.8 bits (120), Expect = 5e-06
Identities = 24/47 (51%), Positives = 29/47 (61%), Gaps = 2/47 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C+DV+EC + + C A A C+N G FQCLC YE DGR CVD
Sbjct: 980 CQDVDECRNRSF--CGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVD 1024
Score = 46.6 bits (109), Expect = 9e-05
Identities = 36/115 (31%), Positives = 49/115 (42%), Gaps = 26/115 (22%)
Query: 542 PEDFESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCR--HGY 599
PE+ S G E + E + ++CG + NG V E ++CR GY
Sbjct: 1445 PEEPPEGGSYAGSLAEPYEEL--EAEECGILDGCTNGRCVRVPEG------FTCRCFDGY 1496
Query: 600 ELQGREQLTCTQEGWDFQPPLCKDVNEC--ADGAHPPCHASARCRNTKGGFQCLC 652
L D C D+NEC A+ A P C +ARC NT G F+C+C
Sbjct: 1497 RL-------------DMTRMACVDINECDEAEAASPLC-VNARCLNTDGSFRCIC 1537
Score = 45.1 bits (105), Expect = 3e-04
Identities = 21/47 (44%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C+DV+ECA PPC RC NT+G FQC+C ++ G C D
Sbjct: 683 CQDVDECARSP-PPC-TYGRCENTEGSFQCVCPMGFQPNTAGSECED 727
Score = 42.7 bits (99), Expect = 0.001
Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 8/91 (8%)
Query: 581 VHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-----WDFQPPLCKDVNECADGAHPPC 635
V C +G V+ C+ E G + +G ++ C+DV+ECA G C
Sbjct: 243 VCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGR--C 300
Query: 636 HASARCRNTKGGFQCLCADPYELGDDGRTCV 666
C NT+GG+ C+C D + L +C+
Sbjct: 301 Q-HGECANTRGGYTCVCPDGFLLDSSRSSCI 330
Score = 42.7 bits (99), Expect = 0.001
Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 2/54 (3%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRV 674
C DV+EC PPC A RC N+ G F+C+C + G C+D RV
Sbjct: 518 CIDVDECRR-VPPPC-APGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRV 569
Score = 42.0 bits (97), Expect = 0.002
Identities = 20/47 (42%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C DV+EC PPC RC NT G F C+C Y+ G +C D
Sbjct: 560 CLDVDEC-HRVPPPCDLG-RCENTPGSFLCVCPAGYQAAPHGASCQD 604
Score = 39.3 bits (90), Expect = 0.014
Identities = 20/48 (41%), Positives = 23/48 (47%), Gaps = 2/48 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 668
C D +ECAD P C RC NT G + C C P L R CV +
Sbjct: 1227 CIDNDECAD-EEPACEGG-RCVNTVGSYHCTCEPPLVLDGSQRRCVSN 1272
Score = 38.5 bits (88), Expect = 0.023
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C DV+EC++ C S C NT G F+C+C + G D +C+D
Sbjct: 851 CLDVDECSE--EDLCQ-SGICTNTDGSFECICPPGHRAGPDLASCLD 894
Score = 37.4 bits (85), Expect = 0.052
Identities = 19/46 (41%), Positives = 22/46 (47%), Gaps = 2/46 (4%)
Query: 622 KDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
+DV+ECA PPC RC NT G F C C + G C D
Sbjct: 642 EDVDECAQEP-PPC-GPGRCDNTAGSFHCACPAGFRSRGPGAPCQD 685
Score = 35.4 bits (80), Expect = 0.20
Identities = 19/49 (38%), Positives = 26/49 (53%), Gaps = 4/49 (8%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCL--CADPYELGDDGRTCVD 667
C DV+EC + C S RC N+ G ++C+ C Y G +G TC D
Sbjct: 892 CLDVDECRERGPALC-GSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDD 938
Score = 32.3 bits (72), Expect = 1.7
Identities = 19/48 (39%), Positives = 23/48 (47%), Gaps = 2/48 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCA-DPYELGDDGRTCVD 667
C DV+EC + C A RC NT G ++C A DP G C D
Sbjct: 936 CDDVDECQEYGPEICGAQ-RCENTPGSYRCTPACDPGYQPTPGGGCQD 982
Score = 30.8 bits (68), Expect = 4.9
Identities = 12/32 (37%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLC 652
C+DV+EC P C+N G F+C+C
Sbjct: 602 CQDVDECTQS--PGLCGRGACKNLPGSFRCVC 631
Score = 30.4 bits (67), Expect = 6.4
Identities = 16/37 (43%), Positives = 20/37 (54%), Gaps = 2/37 (5%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYE 657
C DVNEC + C A A C N +G F C+C + E
Sbjct: 1022 CVDVNEC-ETLQGVCGA-ALCENVEGSFLCVCPNSPE 1056
Score = 30.4 bits (67), Expect = 6.4
Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 1/49 (2%)
Query: 620 LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 668
L +DV+EC C + C NT G+ C C++ Y C+D+
Sbjct: 1183 LRRDVDECQLFRDQVCKSGV-CVNTAPGYSCYCSNGYYYHTQRLECIDN 1230
>gi|110347412 latent transforming growth factor beta binding protein
4 isoform b [Homo sapiens]
Length = 1587
Score = 50.8 bits (120), Expect = 5e-06
Identities = 38/126 (30%), Positives = 48/126 (38%), Gaps = 18/126 (14%)
Query: 542 PEDFESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYEL 601
P F+ +G +L R T + G P +G + E S R SC GY
Sbjct: 776 PGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFR----CSCAPGYRA 831
Query: 602 QGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDD 661
+P C DVNEC +G C C NT G F C CA Y G
Sbjct: 832 PSG------------RPGPCADVNECLEGDF--CFPHGECLNTDGSFACTCAPGYRPGPR 877
Query: 662 GRTCVD 667
G +C+D
Sbjct: 878 GASCLD 883
Score = 50.8 bits (120), Expect = 5e-06
Identities = 24/47 (51%), Positives = 29/47 (61%), Gaps = 2/47 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C+DV+EC + + C A A C+N G FQCLC YE DGR CVD
Sbjct: 1010 CQDVDECRNRSF--CGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVD 1054
Score = 46.6 bits (109), Expect = 9e-05
Identities = 36/115 (31%), Positives = 49/115 (42%), Gaps = 26/115 (22%)
Query: 542 PEDFESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCR--HGY 599
PE+ S G E + E + ++CG + NG V E ++CR GY
Sbjct: 1475 PEEPPEGGSYAGSLAEPYEEL--EAEECGILDGCTNGRCVRVPEG------FTCRCFDGY 1526
Query: 600 ELQGREQLTCTQEGWDFQPPLCKDVNEC--ADGAHPPCHASARCRNTKGGFQCLC 652
L D C D+NEC A+ A P C +ARC NT G F+C+C
Sbjct: 1527 RL-------------DMTRMACVDINECDEAEAASPLC-VNARCLNTDGSFRCIC 1567
Score = 45.1 bits (105), Expect = 3e-04
Identities = 21/47 (44%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C+DV+ECA PPC RC NT+G FQC+C ++ G C D
Sbjct: 713 CQDVDECARSP-PPC-TYGRCENTEGSFQCVCPMGFQPNTAGSECED 757
Score = 42.7 bits (99), Expect = 0.001
Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 8/91 (8%)
Query: 581 VHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-----WDFQPPLCKDVNECADGAHPPC 635
V C +G V+ C+ E G + +G ++ C+DV+ECA G C
Sbjct: 273 VCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGR--C 330
Query: 636 HASARCRNTKGGFQCLCADPYELGDDGRTCV 666
C NT+GG+ C+C D + L +C+
Sbjct: 331 Q-HGECANTRGGYTCVCPDGFLLDSSRSSCI 360
Score = 42.7 bits (99), Expect = 0.001
Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 2/54 (3%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRV 674
C DV+EC PPC A RC N+ G F+C+C + G C+D RV
Sbjct: 548 CIDVDECRR-VPPPC-APGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRV 599
Score = 42.0 bits (97), Expect = 0.002
Identities = 20/47 (42%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C DV+EC PPC RC NT G F C+C Y+ G +C D
Sbjct: 590 CLDVDEC-HRVPPPCDLG-RCENTPGSFLCVCPAGYQAAPHGASCQD 634
Score = 39.3 bits (90), Expect = 0.014
Identities = 20/48 (41%), Positives = 23/48 (47%), Gaps = 2/48 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 668
C D +ECAD P C RC NT G + C C P L R CV +
Sbjct: 1257 CIDNDECAD-EEPACEGG-RCVNTVGSYHCTCEPPLVLDGSQRRCVSN 1302
Score = 38.5 bits (88), Expect = 0.023
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C DV+EC++ C S C NT G F+C+C + G D +C+D
Sbjct: 881 CLDVDECSE--EDLCQ-SGICTNTDGSFECICPPGHRAGPDLASCLD 924
Score = 37.4 bits (85), Expect = 0.052
Identities = 19/46 (41%), Positives = 22/46 (47%), Gaps = 2/46 (4%)
Query: 622 KDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
+DV+ECA PPC RC NT G F C C + G C D
Sbjct: 672 EDVDECAQEP-PPC-GPGRCDNTAGSFHCACPAGFRSRGPGAPCQD 715
Score = 35.4 bits (80), Expect = 0.20
Identities = 19/49 (38%), Positives = 26/49 (53%), Gaps = 4/49 (8%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCL--CADPYELGDDGRTCVD 667
C DV+EC + C S RC N+ G ++C+ C Y G +G TC D
Sbjct: 922 CLDVDECRERGPALC-GSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDD 968
Score = 32.3 bits (72), Expect = 1.7
Identities = 19/48 (39%), Positives = 23/48 (47%), Gaps = 2/48 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCA-DPYELGDDGRTCVD 667
C DV+EC + C A RC NT G ++C A DP G C D
Sbjct: 966 CDDVDECQEYGPEICGAQ-RCENTPGSYRCTPACDPGYQPTPGGGCQD 1012
Score = 30.8 bits (68), Expect = 4.9
Identities = 12/32 (37%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLC 652
C+DV+EC P C+N G F+C+C
Sbjct: 632 CQDVDECTQS--PGLCGRGACKNLPGSFRCVC 661
Score = 30.4 bits (67), Expect = 6.4
Identities = 16/37 (43%), Positives = 20/37 (54%), Gaps = 2/37 (5%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYE 657
C DVNEC + C A A C N +G F C+C + E
Sbjct: 1052 CVDVNEC-ETLQGVCGA-ALCENVEGSFLCVCPNSPE 1086
Score = 30.4 bits (67), Expect = 6.4
Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 1/49 (2%)
Query: 620 LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 668
L +DV+EC C + C NT G+ C C++ Y C+D+
Sbjct: 1213 LRRDVDECQLFRDQVCKSGV-CVNTAPGYSCYCSNGYYYHTQRLECIDN 1260
>gi|110347431 latent transforming growth factor beta binding protein
4 isoform a [Homo sapiens]
Length = 1624
Score = 50.8 bits (120), Expect = 5e-06
Identities = 38/126 (30%), Positives = 48/126 (38%), Gaps = 18/126 (14%)
Query: 542 PEDFESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYEL 601
P F+ +G +L R T + G P +G + E S R SC GY
Sbjct: 813 PGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFR----CSCAPGYRA 868
Query: 602 QGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDD 661
+P C DVNEC +G C C NT G F C CA Y G
Sbjct: 869 PSG------------RPGPCADVNECLEGDF--CFPHGECLNTDGSFACTCAPGYRPGPR 914
Query: 662 GRTCVD 667
G +C+D
Sbjct: 915 GASCLD 920
Score = 50.8 bits (120), Expect = 5e-06
Identities = 24/47 (51%), Positives = 29/47 (61%), Gaps = 2/47 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C+DV+EC + + C A A C+N G FQCLC YE DGR CVD
Sbjct: 1047 CQDVDECRNRSF--CGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVD 1091
Score = 46.6 bits (109), Expect = 9e-05
Identities = 36/115 (31%), Positives = 49/115 (42%), Gaps = 26/115 (22%)
Query: 542 PEDFESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCR--HGY 599
PE+ S G E + E + ++CG + NG V E ++CR GY
Sbjct: 1512 PEEPPEGGSYAGSLAEPYEEL--EAEECGILDGCTNGRCVRVPEG------FTCRCFDGY 1563
Query: 600 ELQGREQLTCTQEGWDFQPPLCKDVNEC--ADGAHPPCHASARCRNTKGGFQCLC 652
L D C D+NEC A+ A P C +ARC NT G F+C+C
Sbjct: 1564 RL-------------DMTRMACVDINECDEAEAASPLC-VNARCLNTDGSFRCIC 1604
Score = 45.1 bits (105), Expect = 3e-04
Identities = 21/47 (44%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C+DV+ECA PPC RC NT+G FQC+C ++ G C D
Sbjct: 750 CQDVDECARSP-PPC-TYGRCENTEGSFQCVCPMGFQPNTAGSECED 794
Score = 42.7 bits (99), Expect = 0.001
Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 8/91 (8%)
Query: 581 VHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-----WDFQPPLCKDVNECADGAHPPC 635
V C +G V+ C+ E G + +G ++ C+DV+ECA G C
Sbjct: 310 VCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGR--C 367
Query: 636 HASARCRNTKGGFQCLCADPYELGDDGRTCV 666
C NT+GG+ C+C D + L +C+
Sbjct: 368 Q-HGECANTRGGYTCVCPDGFLLDSSRSSCI 397
Score = 42.7 bits (99), Expect = 0.001
Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 2/54 (3%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRV 674
C DV+EC PPC A RC N+ G F+C+C + G C+D RV
Sbjct: 585 CIDVDECRR-VPPPC-APGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRV 636
Score = 42.0 bits (97), Expect = 0.002
Identities = 20/47 (42%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C DV+EC PPC RC NT G F C+C Y+ G +C D
Sbjct: 627 CLDVDEC-HRVPPPCDLG-RCENTPGSFLCVCPAGYQAAPHGASCQD 671
Score = 39.3 bits (90), Expect = 0.014
Identities = 20/48 (41%), Positives = 23/48 (47%), Gaps = 2/48 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 668
C D +ECAD P C RC NT G + C C P L R CV +
Sbjct: 1294 CIDNDECAD-EEPACEGG-RCVNTVGSYHCTCEPPLVLDGSQRRCVSN 1339
Score = 38.5 bits (88), Expect = 0.023
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C DV+EC++ C S C NT G F+C+C + G D +C+D
Sbjct: 918 CLDVDECSE--EDLCQ-SGICTNTDGSFECICPPGHRAGPDLASCLD 961
Score = 37.4 bits (85), Expect = 0.052
Identities = 19/46 (41%), Positives = 22/46 (47%), Gaps = 2/46 (4%)
Query: 622 KDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
+DV+ECA PPC RC NT G F C C + G C D
Sbjct: 709 EDVDECAQEP-PPC-GPGRCDNTAGSFHCACPAGFRSRGPGAPCQD 752
Score = 35.4 bits (80), Expect = 0.20
Identities = 19/49 (38%), Positives = 26/49 (53%), Gaps = 4/49 (8%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCL--CADPYELGDDGRTCVD 667
C DV+EC + C S RC N+ G ++C+ C Y G +G TC D
Sbjct: 959 CLDVDECRERGPALC-GSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDD 1005
Score = 32.3 bits (72), Expect = 1.7
Identities = 19/48 (39%), Positives = 23/48 (47%), Gaps = 2/48 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCA-DPYELGDDGRTCVD 667
C DV+EC + C A RC NT G ++C A DP G C D
Sbjct: 1003 CDDVDECQEYGPEICGAQ-RCENTPGSYRCTPACDPGYQPTPGGGCQD 1049
Score = 30.8 bits (68), Expect = 4.9
Identities = 12/32 (37%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLC 652
C+DV+EC P C+N G F+C+C
Sbjct: 669 CQDVDECTQS--PGLCGRGACKNLPGSFRCVC 698
Score = 30.4 bits (67), Expect = 6.4
Identities = 16/37 (43%), Positives = 20/37 (54%), Gaps = 2/37 (5%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYE 657
C DVNEC + C A A C N +G F C+C + E
Sbjct: 1089 CVDVNEC-ETLQGVCGA-ALCENVEGSFLCVCPNSPE 1123
Score = 30.4 bits (67), Expect = 6.4
Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 1/49 (2%)
Query: 620 LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 668
L +DV+EC C + C NT G+ C C++ Y C+D+
Sbjct: 1250 LRRDVDECQLFRDQVCKSGV-CVNTAPGYSCYCSNGYYYHTQRLECIDN 1297
>gi|46249414 latent transforming growth factor beta binding protein 1
isoform LTBP-1L [Homo sapiens]
Length = 1722
Score = 50.4 bits (119), Expect = 6e-06
Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 7/90 (7%)
Query: 582 HCEESGRRVLVYS-CRHGYELQGREQLTCT-QEGWDFQP-PLCKDVNECADGAHPP-CHA 637
HCE+ + S C+ G + CT +G+ C+D+NEC HP C
Sbjct: 1159 HCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECE---HPGLCGP 1215
Query: 638 SARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C NT+G F C+C + + DGRTC D
Sbjct: 1216 QGECLNTEGSFHCVCQQGFSISADGRTCED 1245
Score = 45.1 bits (105), Expect = 3e-04
Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C+D++EC + C + C NT G F+CLC ++ DG+ CVD
Sbjct: 1243 CEDIDECVNNT--VCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVD 1287
Score = 44.7 bits (104), Expect = 3e-04
Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 5/76 (6%)
Query: 595 CRHGYELQGREQLTCT-QEGWDF--QPPLCKDVNECADGAHPPCHASARCRNTKGGFQCL 651
C G+ + + TC EG+ F Q C D++EC H + RC NT+G F C+
Sbjct: 885 CGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQH--LCSQGRCENTEGSFLCI 942
Query: 652 CADPYELGDDGRTCVD 667
C + ++G C+D
Sbjct: 943 CPAGFMASEEGTNCID 958
Score = 43.9 bits (102), Expect = 6e-04
Identities = 30/101 (29%), Positives = 41/101 (40%), Gaps = 20/101 (19%)
Query: 567 DKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNE 626
D+C NG + E S R +C GY+L + C+D++E
Sbjct: 1082 DECQQGNLCVNGQCKNTEGSFR----CTCGQGYQLSAAKDQ-------------CEDIDE 1124
Query: 627 CADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C H A +CRNT+G FQC+C Y G C D
Sbjct: 1125 CQ---HRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCED 1162
Score = 42.0 bits (97), Expect = 0.002
Identities = 30/102 (29%), Positives = 38/102 (37%), Gaps = 18/102 (17%)
Query: 565 QDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDV 624
Q ++CG ENG V +E C GY L D C DV
Sbjct: 1622 QAEECGILNGCENGRCVRVQEG----YTCDCFDGYHL-------------DTAKMTCVDV 1664
Query: 625 NECAD-GAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTC 665
NEC + +A+C NT G ++CLC Y D C
Sbjct: 1665 NECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYC 1706
Score = 41.2 bits (95), Expect = 0.004
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 6/75 (8%)
Query: 595 CRHGYELQGREQLTCTQEGWDFQPPL---CKDVNECADGAHPPCHASARCRNTKGGFQCL 651
C++G+ L R C + + P+ C D++EC D P +C NT+G + C
Sbjct: 1437 CKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQD---PSSCIDGQCVNTEGSYNCF 1493
Query: 652 CADPYELGDDGRTCV 666
C P L + C+
Sbjct: 1494 CTHPMVLDASEKRCI 1508
Score = 36.6 bits (83), Expect = 0.089
Identities = 21/61 (34%), Positives = 29/61 (47%), Gaps = 8/61 (13%)
Query: 609 CTQ--EGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCV 666
CT+ GW+ Q C DV+EC + P A+ C N +G + C C Y D + C
Sbjct: 1026 CTEGFRGWNGQ---CLDVDECLE---PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCR 1079
Query: 667 D 667
D
Sbjct: 1080 D 1080
Score = 32.7 bits (73), Expect = 1.3
Identities = 14/50 (28%), Positives = 22/50 (44%), Gaps = 2/50 (4%)
Query: 618 PPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
P ++NEC +P + C N + C+C + Y + R CVD
Sbjct: 869 PTQVTEINECT--VNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVD 916
Score = 31.6 bits (70), Expect = 2.9
Identities = 16/34 (47%), Positives = 19/34 (55%), Gaps = 2/34 (5%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCAD 654
C DVNEC + C A C N +G F C+CAD
Sbjct: 1285 CVDVNEC-ELLSGVC-GEAFCENVEGSFLCVCAD 1316
Score = 31.2 bits (69), Expect = 3.7
Identities = 23/89 (25%), Positives = 37/89 (41%), Gaps = 15/89 (16%)
Query: 565 QDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDV 624
Q+D CG + + F C++ ++ HGY + + C C+D+
Sbjct: 578 QEDCCGTVGT--SWGFNKCQKCPKK----PSYHGYN----QMMECLPGYKRVNNTFCQDI 627
Query: 625 NECA-DGAHPPCHASARCRNTKGGFQCLC 652
NEC G P + C NT G ++C C
Sbjct: 628 NECQLQGVCP----NGECLNTMGSYRCTC 652
Score = 30.8 bits (68), Expect = 4.9
Identities = 17/53 (32%), Positives = 22/53 (41%), Gaps = 9/53 (16%)
Query: 615 DFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
+ Q C +N C +G RC + G+ C C D Y L TCVD
Sbjct: 1620 ELQAEECGILNGCENG---------RCVRVQEGYTCDCFDGYHLDTAKMTCVD 1663
>gi|46249412 latent transforming growth factor beta binding protein
1 isoform LTBP-1S [Homo sapiens]
Length = 1396
Score = 50.4 bits (119), Expect = 6e-06
Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 7/90 (7%)
Query: 582 HCEESGRRVLVYS-CRHGYELQGREQLTCT-QEGWDFQP-PLCKDVNECADGAHPP-CHA 637
HCE+ + S C+ G + CT +G+ C+D+NEC HP C
Sbjct: 833 HCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECE---HPGLCGP 889
Query: 638 SARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C NT+G F C+C + + DGRTC D
Sbjct: 890 QGECLNTEGSFHCVCQQGFSISADGRTCED 919
Score = 45.1 bits (105), Expect = 3e-04
Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C+D++EC + C + C NT G F+CLC ++ DG+ CVD
Sbjct: 917 CEDIDECVNNT--VCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVD 961
Score = 44.7 bits (104), Expect = 3e-04
Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 5/76 (6%)
Query: 595 CRHGYELQGREQLTCT-QEGWDF--QPPLCKDVNECADGAHPPCHASARCRNTKGGFQCL 651
C G+ + + TC EG+ F Q C D++EC H + RC NT+G F C+
Sbjct: 559 CGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQH--LCSQGRCENTEGSFLCI 616
Query: 652 CADPYELGDDGRTCVD 667
C + ++G C+D
Sbjct: 617 CPAGFMASEEGTNCID 632
Score = 43.9 bits (102), Expect = 6e-04
Identities = 30/101 (29%), Positives = 41/101 (40%), Gaps = 20/101 (19%)
Query: 567 DKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNE 626
D+C NG + E S R +C GY+L + C+D++E
Sbjct: 756 DECQQGNLCVNGQCKNTEGSFR----CTCGQGYQLSAAKDQ-------------CEDIDE 798
Query: 627 CADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C H A +CRNT+G FQC+C Y G C D
Sbjct: 799 CQ---HRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCED 836
Score = 42.0 bits (97), Expect = 0.002
Identities = 30/102 (29%), Positives = 38/102 (37%), Gaps = 18/102 (17%)
Query: 565 QDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDV 624
Q ++CG ENG V +E C GY L D C DV
Sbjct: 1296 QAEECGILNGCENGRCVRVQEG----YTCDCFDGYHL-------------DTAKMTCVDV 1338
Query: 625 NECAD-GAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTC 665
NEC + +A+C NT G ++CLC Y D C
Sbjct: 1339 NECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYC 1380
Score = 41.2 bits (95), Expect = 0.004
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 6/75 (8%)
Query: 595 CRHGYELQGREQLTCTQEGWDFQPPL---CKDVNECADGAHPPCHASARCRNTKGGFQCL 651
C++G+ L R C + + P+ C D++EC D P +C NT+G + C
Sbjct: 1111 CKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQD---PSSCIDGQCVNTEGSYNCF 1167
Query: 652 CADPYELGDDGRTCV 666
C P L + C+
Sbjct: 1168 CTHPMVLDASEKRCI 1182
Score = 36.6 bits (83), Expect = 0.089
Identities = 21/61 (34%), Positives = 29/61 (47%), Gaps = 8/61 (13%)
Query: 609 CTQ--EGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCV 666
CT+ GW+ Q C DV+EC + P A+ C N +G + C C Y D + C
Sbjct: 700 CTEGFRGWNGQ---CLDVDECLE---PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCR 753
Query: 667 D 667
D
Sbjct: 754 D 754
Score = 32.7 bits (73), Expect = 1.3
Identities = 14/50 (28%), Positives = 22/50 (44%), Gaps = 2/50 (4%)
Query: 618 PPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
P ++NEC +P + C N + C+C + Y + R CVD
Sbjct: 543 PTQVTEINECT--VNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVD 590
Score = 31.6 bits (70), Expect = 2.9
Identities = 16/34 (47%), Positives = 19/34 (55%), Gaps = 2/34 (5%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCAD 654
C DVNEC + C A C N +G F C+CAD
Sbjct: 959 CVDVNEC-ELLSGVC-GEAFCENVEGSFLCVCAD 990
Score = 31.2 bits (69), Expect = 3.7
Identities = 23/89 (25%), Positives = 37/89 (41%), Gaps = 15/89 (16%)
Query: 565 QDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDV 624
Q+D CG + + F C++ ++ HGY + + C C+D+
Sbjct: 252 QEDCCGTVGT--SWGFNKCQKCPKK----PSYHGYN----QMMECLPGYKRVNNTFCQDI 301
Query: 625 NECA-DGAHPPCHASARCRNTKGGFQCLC 652
NEC G P + C NT G ++C C
Sbjct: 302 NECQLQGVCP----NGECLNTMGSYRCTC 326
Score = 30.8 bits (68), Expect = 4.9
Identities = 17/53 (32%), Positives = 22/53 (41%), Gaps = 9/53 (16%)
Query: 615 DFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
+ Q C +N C +G RC + G+ C C D Y L TCVD
Sbjct: 1294 ELQAEECGILNGCENG---------RCVRVQEGYTCDCFDGYHLDTAKMTCVD 1337
>gi|4557733 latent transforming growth factor beta binding protein 2
[Homo sapiens]
Length = 1821
Score = 48.1 bits (113), Expect = 3e-05
Identities = 28/88 (31%), Positives = 39/88 (44%), Gaps = 5/88 (5%)
Query: 582 HCEESGRRVLVYSCRHGYELQGREQLTCT--QEGWDFQPPLCKDVNECADGAHPPCHASA 639
HC++ +C G + TC +EG+ Q C DVNEC P A
Sbjct: 967 HCQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLT---PGVCAHG 1023
Query: 640 RCRNTKGGFQCLCADPYELGDDGRTCVD 667
+C N +G F+C C YE+ D + C D
Sbjct: 1024 KCTNLEGSFRCSCEQGYEVTSDEKGCQD 1051
Score = 47.4 bits (111), Expect = 5e-05
Identities = 35/98 (35%), Positives = 46/98 (46%), Gaps = 6/98 (6%)
Query: 572 PESVENGDFVHCEESGRRVL-VYSCRHGYELQGREQLTCTQEGWDFQPPL-CKDVNECAD 629
PES E D CE+ G V + C + R L C Q G+ P C D++ECA+
Sbjct: 1252 PESGECVDIDECEDYGDPVCGTWKCENSPGSY-RCVLGC-QPGFHMAPNGDCIDIDECAN 1309
Query: 630 GAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C + C NT G F+CLC +E+ G CVD
Sbjct: 1310 DTM--CGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVD 1345
Score = 46.2 bits (108), Expect = 1e-04
Identities = 28/89 (31%), Positives = 37/89 (41%), Gaps = 5/89 (5%)
Query: 579 DFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHAS 638
D CE+ L C++ G Q C Q +C+DVNEC H C
Sbjct: 1135 DVDECEDPQSSCLGGECKNTV---GSYQCLCPQGFQLANGTVCEDVNECMGEEH--CAPH 1189
Query: 639 ARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C N+ G F CLCA + + G +C D
Sbjct: 1190 GECLNSHGSFFCLCAPGFVSAEGGTSCQD 1218
Score = 44.7 bits (104), Expect = 3e-04
Identities = 33/102 (32%), Positives = 47/102 (46%), Gaps = 21/102 (20%)
Query: 567 DKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNE 626
++C P +G + E S R SC GYE+ T ++G C+DV+E
Sbjct: 1012 NECLTPGVCAHGKCTNLEGSFR----CSCEQGYEV------TSDEKG-------CQDVDE 1054
Query: 627 CADGAHPPCHASARCRNTKGGFQC-LCADPYELGDDGRTCVD 667
CA A P + C NT+G F C C + Y + +DG C D
Sbjct: 1055 CASRASCP---TGLCLNTEGSFACSACENGYWVNEDGTACED 1093
Score = 40.8 bits (94), Expect = 0.005
Identities = 19/47 (40%), Positives = 25/47 (53%), Gaps = 3/47 (6%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C+DV+ECA PC C NT+G F CLC ++ + CVD
Sbjct: 1216 CQDVDECA--TTDPC-VGGHCVNTEGSFNCLCETGFQPSPESGECVD 1259
Score = 40.8 bits (94), Expect = 0.005
Identities = 39/129 (30%), Positives = 50/129 (38%), Gaps = 25/129 (19%)
Query: 544 DFESCDSITGMNLEAWR-ETFPQDDKC------GFPESVENGDFVHCEESGRRVLVYSCR 596
D + C+ W+ E P +C GF NGD + +E + S
Sbjct: 1259 DIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGF-HMAPNGDCIDIDECANDTMCGS-- 1315
Query: 597 HGY--ELQGREQLTCTQ------EGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGF 648
HG+ G + C Q GWD C DVNEC + C A A C N +G F
Sbjct: 1316 HGFCDNTDGSFRCLCDQGFEISPSGWD-----CVDVNEC-ELMLAVCGA-ALCENVEGSF 1368
Query: 649 QCLCADPYE 657
CLCA E
Sbjct: 1369 LCLCASDLE 1377
Score = 38.9 bits (89), Expect = 0.018
Identities = 29/89 (32%), Positives = 41/89 (46%), Gaps = 7/89 (7%)
Query: 572 PESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQ-EGW--DFQPPLCKDVNECA 628
PE + + EE G ++ C +G ++ RE TC EG+ D C DVNEC
Sbjct: 1723 PEPPAGFEGLQAEECG---ILNGCENGRCVRVREGYTCDCFEGFQLDAAHMACVDVNECD 1779
Query: 629 DGAHPPCHA-SARCRNTKGGFQCLCADPY 656
D P C NT+G ++C C+ Y
Sbjct: 1780 DLNGPAVLCVHGYCENTEGSYRCHCSPGY 1808
Score = 37.4 bits (85), Expect = 0.052
Identities = 17/44 (38%), Positives = 18/44 (40%), Gaps = 3/44 (6%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRT 664
C D NEC PC RC N G + C C Y L G T
Sbjct: 885 CTDDNECL---RDPCKGKGRCINRVGSYSCFCYPGYTLATSGAT 925
Score = 36.6 bits (83), Expect = 0.089
Identities = 19/55 (34%), Positives = 28/55 (50%), Gaps = 4/55 (7%)
Query: 614 WDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 668
+D C+D +EC D A C + C NT+G F C C+ P L + C++S
Sbjct: 1519 YDASHKKCEDHDECQDLA---CE-NGECVNTEGSFHCFCSPPLTLDLSQQRCMNS 1569
Score = 34.3 bits (77), Expect = 0.44
Identities = 27/79 (34%), Positives = 34/79 (43%), Gaps = 19/79 (24%)
Query: 583 CEESGR---RVLVYSC--RHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHA 637
C+ GR RV YSC GY L TQE C+D+NEC P +
Sbjct: 896 CKGKGRCINRVGSYSCFCYPGYTLATSG---ATQE--------CQDINECEQ---PGVCS 941
Query: 638 SARCRNTKGGFQCLCADPY 656
+C NT+G + C C Y
Sbjct: 942 GGQCTNTEGSYHCECDQGY 960
Score = 32.0 bits (71), Expect = 2.2
Identities = 15/50 (30%), Positives = 22/50 (44%), Gaps = 1/50 (2%)
Query: 624 VNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPR 673
++ CA GA C C N G++C+C+ Y+L C D R
Sbjct: 845 IDRCAAGATNVC-GPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLR 893
Score = 31.6 bits (70), Expect = 2.9
Identities = 16/54 (29%), Positives = 22/54 (40%), Gaps = 1/54 (1%)
Query: 614 WDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
W F + D +EC C + RC NT G+ CLC + + C D
Sbjct: 1476 WTFGQTMYTDADECVIFGPGLC-PNGRCLNTVPGYVCLCNPGFHYDASHKKCED 1528
Score = 31.2 bits (69), Expect = 3.7
Identities = 19/61 (31%), Positives = 23/61 (37%), Gaps = 3/61 (4%)
Query: 606 QLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTC 665
QL C Q C+D+NEC A C NT+G + C C L C
Sbjct: 605 QLECPQGYKRLNLTHCQDINECLTLG---LCKDAECVNTRGSYLCTCRPGLMLDPSRSRC 661
Query: 666 V 666
V
Sbjct: 662 V 662
Score = 30.8 bits (68), Expect = 4.9
Identities = 18/48 (37%), Positives = 22/48 (45%), Gaps = 4/48 (8%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCL-CADPYELGDDGRTCVD 667
C+D++ECA P S C NT G F C C Y G +C D
Sbjct: 1091 CEDLDECA---FPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCED 1135
>gi|190343004 EGF-containing fibulin-like extracellular matrix
protein 2 [Homo sapiens]
Length = 443
Score = 48.1 bits (113), Expect = 3e-05
Identities = 45/142 (31%), Positives = 60/142 (42%), Gaps = 23/142 (16%)
Query: 539 GKFPEDFESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRR-----VLVY 593
G P+D +SC + +A + P D P S + C + R+ V +
Sbjct: 112 GYEPDDQDSCVDVDEC-AQALHDCRPSQDCHNLPGSYQ----CTCPDGYRKIGPECVDID 166
Query: 594 SCRHGY------ELQGREQLTCTQEGWDFQPP--LCKDVNECADGAHPPCHASARCRNTK 645
CR+ Y L G + C + G+ P C DVNEC GA PC RC N+
Sbjct: 167 ECRYRYCQHRCVNLPGSFRCQC-EPGFQLGPNNRSCVDVNECDMGA--PCEQ--RCFNSY 221
Query: 646 GGFQCLCADPYELGDDGRTCVD 667
G F C C YEL DG +C D
Sbjct: 222 GTFLCRCHQGYELHRDGFSCSD 243
Score = 42.0 bits (97), Expect = 0.002
Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 6/76 (7%)
Query: 603 GREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCL----CADPY-E 657
GR C Q LC+D++EC GAH C + C N GG++C+ C +PY +
Sbjct: 263 GRFSCHCPQGYQLLATRLCQDIDECESGAH-QCSEAQTCVNFHGGYRCVDTNRCVEPYIQ 321
Query: 658 LGDDGRTCVDSGRLPR 673
+ ++ C S L R
Sbjct: 322 VSENRCLCPASNPLCR 337
Score = 33.1 bits (74), Expect = 0.99
Identities = 19/57 (33%), Positives = 22/57 (38%), Gaps = 14/57 (24%)
Query: 595 CRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCL 651
C GYE WD C+DVNEC C +C N GG+ CL
Sbjct: 39 CTDGYE-------------WDPDSQHCRDVNECLT-IPEACKGEMKCINHYGGYLCL 81
Score = 32.0 bits (71), Expect = 2.2
Identities = 19/64 (29%), Positives = 28/64 (43%), Gaps = 16/64 (25%)
Query: 595 CRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCAD 654
C GYEL ++G+ C D++EC+ ++ RC N G F C C
Sbjct: 228 CHQGYELH--------RDGFS-----CSDIDECSYSSYL---CQYRCVNEPGRFSCHCPQ 271
Query: 655 PYEL 658
Y+L
Sbjct: 272 GYQL 275
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 47.8 bits (112), Expect = 4e-05
Identities = 20/54 (37%), Positives = 29/54 (53%), Gaps = 1/54 (1%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRV 674
C D++EC DG H C + C NT+G ++C+C Y GR C+D +V
Sbjct: 5270 CIDIDECKDGTHQ-CRYNQICENTRGSYRCVCPRGYRSQGVGRPCMDINECEQV 5322
Score = 47.0 bits (110), Expect = 7e-05
Identities = 21/52 (40%), Positives = 27/52 (51%), Gaps = 3/52 (5%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLP 672
C D+NEC P H +C NT G F+C+C L DG++C RLP
Sbjct: 5313 CMDINECEQVPKPCAH---QCSNTPGSFKCICPPGQHLLGDGKSCAGLERLP 5361
Score = 45.4 bits (106), Expect = 2e-04
Identities = 25/75 (33%), Positives = 36/75 (48%), Gaps = 21/75 (28%)
Query: 595 CRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQC--LC 652
C GY+L+GR+ C DVNEC C C+NT+GG++C LC
Sbjct: 5217 CEPGYQLKGRK---------------CMDVNECRQNV---CRPDQHCKNTRGGYKCIDLC 5258
Query: 653 ADPYELGDDGRTCVD 667
+ ++G TC+D
Sbjct: 5259 PNGMTKAENG-TCID 5272
Score = 44.7 bits (104), Expect = 3e-04
Identities = 20/49 (40%), Positives = 28/49 (57%), Gaps = 3/49 (6%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCL--CADPYELGDDGRTCVD 667
C+D++ECA G H CHA C NT G ++C+ C + DG +C D
Sbjct: 5145 CQDIDECALGRHT-CHAGQDCDNTIGSYRCVVRCGSGFRRTSDGLSCQD 5192
Score = 42.7 bits (99), Expect = 0.001
Identities = 21/47 (44%), Positives = 27/47 (57%), Gaps = 6/47 (12%)
Query: 621 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
C+D+NEC + + PCH RC N G F C C Y+L GR C+D
Sbjct: 5190 CQDINECQESS--PCHQ--RCFNAIGSFHCGCEPGYQL--KGRKCMD 5230
Score = 42.7 bits (99), Expect = 0.001
Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 5/60 (8%)
Query: 608 TCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
TC EG + C D++EC + C+NT G +QC+C Y+L +G+TC D
Sbjct: 5418 TCP-EGSEASHDTCVDIDECENTDA----CQHECKNTFGSYQCICPPGYQLTHNGKTCQD 5472
Score = 41.6 bits (96), Expect = 0.003
Identities = 21/49 (42%), Positives = 24/49 (48%), Gaps = 4/49 (8%)
Query: 619 PLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 667
P C D +ECA G PC S C N G + C C + DGRTC D
Sbjct: 5103 PFCADEDECAAGN--PCSHS--CHNAMGTYYCSCPKGLTIAADGRTCQD 5147
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.433
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,746,050
Number of Sequences: 37866
Number of extensions: 1500921
Number of successful extensions: 4733
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 129
Number of HSP's successfully gapped in prelim test: 92
Number of HSP's that attempted gapping in prelim test: 3343
Number of HSP's gapped (non-prelim): 1187
length of query: 760
length of database: 18,247,518
effective HSP length: 110
effective length of query: 650
effective length of database: 14,082,258
effective search space: 9153467700
effective search space used: 9153467700
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.