Guide to the Human Genome
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Name: TPO Sequence: fasta or formatted (889aa) NCBI GI: 28558988
Description:

thyroid peroxidase isoform d

Referenced in:

Superoxide Pathway
Thyroid and Thyroid Hormone Receptor

Other entries for this name:
alt prot [933aa] thyroid peroxidase isoform a
alt prot [876aa] thyroid peroxidase isoform b
alt prot [760aa] thyroid peroxidase isoform e
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.2         82           3
 C cysteine            2.6         23           1
 D aspartate           4.9         44           3
 E glutamate           5.8         52           2
 F phenylalanine       4.0         36           2
 G glycine             7.8         69           3
 H histidine           2.4         21           1
 I isoleucine          3.4         30           2
 K lysine              2.8         25           2
 L leucine            10.8         96           2
 M methionine          1.9         17           1
 N asparagine          3.5         31           2
 P proline             7.1         63           2
 Q glutamine           4.4         39           2
 R arginine            7.4         66           2
 S serine              7.0         62           2
 T threonine           6.1         54           1
 V valine              4.6         41           2
 W tryptophan          2.1         19           2
 Y tyrosine            2.1         19           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   thyroid peroxidase isoform d 
TPO                   0.988   thyroid peroxidase isoform a 
TPO                   0.910   thyroid peroxidase isoform b 
TPO                   0.486   thyroid peroxidase isoform e 
MPO                   0.321   myeloperoxidase 
EPX                   0.316   eosinophil peroxidase 
LPO                   0.285   lactoperoxidase isoform 1 preproprotein 
PXDN                  0.284   peroxidasin 
LPO                   0.281   lactoperoxidase isoform 3 preproprotein 
PXDNL                 0.248   peroxidasin homolog-like 
DUOX1                 0.058   dual oxidase 1 precursor 
DUOX1                 0.058   dual oxidase 1 precursor 
DUOX2                 0.053   dual oxidase 2 precursor 
PTGS2                 0.018   prostaglandin-endoperoxide synthase 2 precursor [Homo...
PTGS1                 0.014   prostaglandin-endoperoxide synthase 1 isoform 2 prec...
PTGS1                 0.014   prostaglandin-endoperoxide synthase 1 isoform 1 prec...
SVEP1                 0.012   polydom 
CFHR2                 0.011   H factor (complement)-like 3 
CFH                   0.009   complement factor H isoform a precursor 
CSMD1                 0.009   CUB and Sushi multiple domains 1 
SEZ6L                 0.009   seizure related 6 homolog (mouse)-like precursor [Ho...
CFHR1                 0.009   complement factor H-related 1 
C4BPA                 0.009   complement component 4 binding protein, alpha chain p...
LOC100293069          0.009   PREDICTED: similar to complement factor H-related 1...
CFHR4                 0.008   complement factor H-related 4 
CD55                  0.008   decay accelerating factor for complement isoform 2 ...
CD55                  0.008   decay accelerating factor for complement isoform 1 p...
SEZ6L2                0.008   seizure related 6 homolog (mouse)-like 2 isoform 4 ...
SEZ6L2                0.008   seizure related 6 homolog (mouse)-like 2 isoform 3 ...
SEZ6L2                0.008   seizure related 6 homolog (mouse)-like 2 isoform 2 ...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
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