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Search of human proteins with 28558984
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28558984 thyroid peroxidase isoform b [Homo sapiens]
(876 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28558984 thyroid peroxidase isoform b [Homo sapiens] 1824 0.0
gi|28558982 thyroid peroxidase isoform a [Homo sapiens] 1793 0.0
gi|28558988 thyroid peroxidase isoform d [Homo sapiens] 1671 0.0
gi|28558990 thyroid peroxidase isoform e [Homo sapiens] 885 0.0
gi|4557759 myeloperoxidase [Homo sapiens] 520 e-147
gi|4503595 eosinophil peroxidase [Homo sapiens] 508 e-143
gi|40549418 lactoperoxidase isoform 1 preproprotein [Homo sapiens] 452 e-127
gi|231569458 lactoperoxidase isoform 3 preproprotein [Homo sapiens] 446 e-125
gi|109150416 peroxidasin [Homo sapiens] 443 e-124
gi|126517478 peroxidasin homolog-like [Homo sapiens] 393 e-109
gi|20149640 dual oxidase 1 precursor [Homo sapiens] 101 3e-21
gi|28872751 dual oxidase 1 precursor [Homo sapiens] 101 3e-21
gi|132566532 dual oxidase 2 precursor [Homo sapiens] 79 1e-14
gi|148886654 polydom [Homo sapiens] 72 2e-12
gi|194328809 latent transforming growth factor beta binding prot... 64 5e-10
gi|18497288 latent transforming growth factor beta binding prote... 64 5e-10
gi|4506265 prostaglandin-endoperoxide synthase 2 precursor [Homo... 57 1e-07
gi|24430141 fibrillin 1 precursor [Homo sapiens] 55 4e-07
gi|66346695 fibrillin 2 precursor [Homo sapiens] 52 2e-06
gi|56237021 fibrillin 3 precursor [Homo sapiens] 52 2e-06
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 52 2e-06
gi|157384998 low density lipoprotein receptor-related protein 4 ... 51 4e-06
gi|122937283 6720455I24Rik homolog [Homo sapiens] 51 4e-06
gi|110347437 latent transforming growth factor beta binding prot... 51 5e-06
gi|110347412 latent transforming growth factor beta binding prot... 51 5e-06
gi|110347431 latent transforming growth factor beta binding prot... 51 5e-06
gi|46249414 latent transforming growth factor beta binding prote... 50 7e-06
gi|46249412 latent transforming growth factor beta binding prote... 50 7e-06
gi|18104969 prostaglandin-endoperoxide synthase 1 isoform 2 prec... 50 9e-06
gi|18104967 prostaglandin-endoperoxide synthase 1 isoform 1 prec... 50 9e-06
>gi|28558984 thyroid peroxidase isoform b [Homo sapiens]
Length = 876
Score = 1824 bits (4725), Expect = 0.0
Identities = 876/876 (100%), Positives = 876/876 (100%)
Query: 1 MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR 60
MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR
Sbjct: 1 MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR 60
Query: 61 NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS 120
NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS
Sbjct: 61 NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS 120
Query: 121 EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV 180
EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV
Sbjct: 121 EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV 180
Query: 181 YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD 240
YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD
Sbjct: 181 YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD 240
Query: 241 IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQLPEEARPAAGTACLPFYRSSAACGTGD 300
IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQLPEEARPAAGTACLPFYRSSAACGTGD
Sbjct: 241 IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQLPEEARPAAGTACLPFYRSSAACGTGD 300
Query: 301 QGALFGNLSTANPRQQMNGLTSFLDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSG 360
QGALFGNLSTANPRQQMNGLTSFLDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSG
Sbjct: 301 QGALFGNLSTANPRQQMNGLTSFLDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSG 360
Query: 361 RAYLPFVPPRAPAACAPEPGIPGETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAA 420
RAYLPFVPPRAPAACAPEPGIPGETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAA
Sbjct: 361 RAYLPFVPPRAPAACAPEPGIPGETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAA 420
Query: 421 LKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPT 480
LKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPT
Sbjct: 421 LKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPT 480
Query: 481 VSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGLWLHQAFFSPWTLLRGGYNEWREF 540
VSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGLWLHQAFFSPWTLLRGGYNEWREF
Sbjct: 481 VSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGLWLHQAFFSPWTLLRGGYNEWREF 540
Query: 541 CGLPRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTGPLFACLI 600
CGLPRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTGPLFACLI
Sbjct: 541 CGLPRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTGPLFACLI 600
Query: 601 GKQMKALRDGDWFWWENSHVFTDAQRRELEKHSLSRVICDNTGLTRVPMDAFQVGKFPED 660
GKQMKALRDGDWFWWENSHVFTDAQRRELEKHSLSRVICDNTGLTRVPMDAFQVGKFPED
Sbjct: 601 GKQMKALRDGDWFWWENSHVFTDAQRRELEKHSLSRVICDNTGLTRVPMDAFQVGKFPED 660
Query: 661 FESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGR 720
FESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGR
Sbjct: 661 FESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGR 720
Query: 721 EQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRT 780
EQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRT
Sbjct: 721 EQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRT 780
Query: 781 CVDSGRLPRVTWISMSLAALLIGGFAGLTSTVICRWTRTGTKSTLPISETGGGTPELRCG 840
CVDSGRLPRVTWISMSLAALLIGGFAGLTSTVICRWTRTGTKSTLPISETGGGTPELRCG
Sbjct: 781 CVDSGRLPRVTWISMSLAALLIGGFAGLTSTVICRWTRTGTKSTLPISETGGGTPELRCG 840
Query: 841 KHQAVGTSPQRAAAQDSEQESAGMEGRDTHRLPRAL 876
KHQAVGTSPQRAAAQDSEQESAGMEGRDTHRLPRAL
Sbjct: 841 KHQAVGTSPQRAAAQDSEQESAGMEGRDTHRLPRAL 876
>gi|28558982 thyroid peroxidase isoform a [Homo sapiens]
Length = 933
Score = 1793 bits (4644), Expect = 0.0
Identities = 875/933 (93%), Positives = 876/933 (93%), Gaps = 57/933 (6%)
Query: 1 MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR 60
MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR
Sbjct: 1 MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR 60
Query: 61 NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS 120
NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS
Sbjct: 61 NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS 120
Query: 121 EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV 180
EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV
Sbjct: 121 EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV 180
Query: 181 YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD 240
YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD
Sbjct: 181 YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD 240
Query: 241 IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQLPEEARPAAGTACLPFYRSSAACGTGD 300
IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQLPEEARPAAGTACLPFYRSSAACGTGD
Sbjct: 241 IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQLPEEARPAAGTACLPFYRSSAACGTGD 300
Query: 301 QGALFGNLSTANPRQQMNGLTSFLDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSG 360
QGALFGNLSTANPRQQMNGLTSFLDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSG
Sbjct: 301 QGALFGNLSTANPRQQMNGLTSFLDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSG 360
Query: 361 RAYLPFVPPRAPAACAPEPGIPGETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAA 420
RAYLPFVPPRAPAACAPEPGIPGETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAA
Sbjct: 361 RAYLPFVPPRAPAACAPEPGIPGETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAA 420
Query: 421 LKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPT 480
LKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPT
Sbjct: 421 LKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPT 480
Query: 481 VSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGLWLHQAFFSPWT---------LLR 531
VSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGLWLHQAFFSPWT L+R
Sbjct: 481 VSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIR 540
Query: 532 G------------------------------------------------GYNEWREFCGL 543
G GYNEWREFCGL
Sbjct: 541 GLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGL 600
Query: 544 PRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQ 603
PRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQ
Sbjct: 601 PRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQ 660
Query: 604 MKALRDGDWFWWENSHVFTDAQRRELEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFES 663
MKALRDGDWFWWENSHVFTDAQRRELEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFES
Sbjct: 661 MKALRDGDWFWWENSHVFTDAQRRELEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFES 720
Query: 664 CDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQL 723
CDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQL
Sbjct: 721 CDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQL 780
Query: 724 TCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
TCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD
Sbjct: 781 TCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 840
Query: 784 SGRLPRVTWISMSLAALLIGGFAGLTSTVICRWTRTGTKSTLPISETGGGTPELRCGKHQ 843
SGRLPRVTWISMSLAALLIGGFAGLTSTVICRWTRTGTKSTLPISETGGGTPELRCGKHQ
Sbjct: 841 SGRLPRVTWISMSLAALLIGGFAGLTSTVICRWTRTGTKSTLPISETGGGTPELRCGKHQ 900
Query: 844 AVGTSPQRAAAQDSEQESAGMEGRDTHRLPRAL 876
AVGTSPQRAAAQDSEQESAGMEGRDTHRLPRAL
Sbjct: 901 AVGTSPQRAAAQDSEQESAGMEGRDTHRLPRAL 933
>gi|28558988 thyroid peroxidase isoform d [Homo sapiens]
Length = 889
Score = 1671 bits (4328), Expect = 0.0
Identities = 831/933 (89%), Positives = 832/933 (89%), Gaps = 101/933 (10%)
Query: 1 MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR 60
MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR
Sbjct: 1 MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR 60
Query: 61 NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS 120
NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS
Sbjct: 61 NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS 120
Query: 121 EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV 180
EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV
Sbjct: 121 EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV 180
Query: 181 YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD 240
YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD
Sbjct: 181 YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD 240
Query: 241 IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQLPEEARPAAGTACLPFYRSSAACGTGD 300
IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQLPEEARPAAGTACLPFYRSSAACGTGD
Sbjct: 241 IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQLPEEARPAAGTACLPFYRSSAACGTGD 300
Query: 301 QGALFGNLSTANPRQQMNGLTSFLDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSG 360
QGALFGNLSTANPRQQMNGLTSFLDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSG
Sbjct: 301 QGALFGNLSTANPRQQMNGLTSFLDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSG 360
Query: 361 RAYLPFVPPRAPAACAPEPGIPGETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAA 420
RAYLPFVPPRAPAACAPEPGIPGETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAA
Sbjct: 361 RAYLPFVPPRAPAACAPEPGIPGETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAA 420
Query: 421 LKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPT 480
LKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPT
Sbjct: 421 LKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPT 480
Query: 481 VSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGLWLHQAFFSPWT---------LLR 531
VSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGLWLHQAFFSPWT L+R
Sbjct: 481 VSNVFSTAAFRFGHATIHPLVRRLDASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIR 540
Query: 532 G------------------------------------------------GYNEWREFCGL 543
G GYNEWREFCGL
Sbjct: 541 GLLARPAKLQVQDQLMNEELTERLFVLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGL 600
Query: 544 PRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQ 603
PRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQ
Sbjct: 601 PRLETPADLSTAIASRSVADKILDLYKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQ 660
Query: 604 MKALRDGDWFWWENSHVFTDAQRRELEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFES 663
MKALRDGDWFWWENSHVFTDAQRRELEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFES
Sbjct: 661 MKALRDGDWFWWENSHVFTDAQRRELEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFES 720
Query: 664 CDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQL 723
CDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQL
Sbjct: 721 CDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQL 780
Query: 724 TCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
TCTQEGWDFQPPLCK D
Sbjct: 781 TCTQEGWDFQPPLCK--------------------------------------------D 796
Query: 784 SGRLPRVTWISMSLAALLIGGFAGLTSTVICRWTRTGTKSTLPISETGGGTPELRCGKHQ 843
SGRLPRVTWISMSLAALLIGGFAGLTSTVICRWTRTGTKSTLPISETGGGTPELRCGKHQ
Sbjct: 797 SGRLPRVTWISMSLAALLIGGFAGLTSTVICRWTRTGTKSTLPISETGGGTPELRCGKHQ 856
Query: 844 AVGTSPQRAAAQDSEQESAGMEGRDTHRLPRAL 876
AVGTSPQRAAAQDSEQESAGMEGRDTHRLPRAL
Sbjct: 857 AVGTSPQRAAAQDSEQESAGMEGRDTHRLPRAL 889
>gi|28558990 thyroid peroxidase isoform e [Homo sapiens]
Length = 760
Score = 885 bits (2287), Expect = 0.0
Identities = 430/488 (88%), Positives = 431/488 (88%), Gaps = 57/488 (11%)
Query: 446 QIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLD 505
QIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLD
Sbjct: 273 QIITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLD 332
Query: 506 ASFQEHPDLPGLWLHQAFFSPWT---------LLRG------------------------ 532
ASFQEHPDLPGLWLHQAFFSPWT L+RG
Sbjct: 333 ASFQEHPDLPGLWLHQAFFSPWTLLRGGGLDPLIRGLLARPAKLQVQDQLMNEELTERLF 392
Query: 533 ------------------------GYNEWREFCGLPRLETPADLSTAIASRSVADKILDL 568
GYNEWREFCGLPRLETPADLSTAIASRSVADKILDL
Sbjct: 393 VLSNSSTLDLASINLQRGRDHGLPGYNEWREFCGLPRLETPADLSTAIASRSVADKILDL 452
Query: 569 YKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRE 628
YKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRE
Sbjct: 453 YKHPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRE 512
Query: 629 LEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDKCGFP 688
LEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDKCGFP
Sbjct: 513 LEKHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDKCGFP 572
Query: 689 ESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAH 748
ESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAH
Sbjct: 573 ESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAH 632
Query: 749 PPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRVTWISMSLAALLIGGFAGL 808
PPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRVTWISMSLAALLIGGFAGL
Sbjct: 633 PPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRVTWISMSLAALLIGGFAGL 692
Query: 809 TSTVICRWTRTGTKSTLPISETGGGTPELRCGKHQAVGTSPQRAAAQDSEQESAGMEGRD 868
TSTVICRWTRTGTKSTLPISETGGGTPELRCGKHQAVGTSPQRAAAQDSEQESAGMEGRD
Sbjct: 693 TSTVICRWTRTGTKSTLPISETGGGTPELRCGKHQAVGTSPQRAAAQDSEQESAGMEGRD 752
Query: 869 THRLPRAL 876
THRLPRAL
Sbjct: 753 THRLPRAL 760
Score = 564 bits (1453), Expect = e-160
Identities = 273/274 (99%), Positives = 274/274 (100%)
Query: 1 MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR 60
MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR
Sbjct: 1 MRALAVLSVTLVMACTEAFFPFISRGKELLWGKPEESRVSSVLEESKRLVDTAMYATMQR 60
Query: 61 NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS 120
NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS
Sbjct: 61 NLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQAMKRKVNLKTQQSQHPTDALS 120
Query: 121 EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV 180
EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV
Sbjct: 121 EDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPITGACNNRDHPRWGASNTALARWLPPV 180
Query: 181 YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD 240
YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD
Sbjct: 181 YEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHD 240
Query: 241 IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQL 274
IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQ+
Sbjct: 241 IAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQI 274
>gi|4557759 myeloperoxidase [Homo sapiens]
Length = 745
Score = 520 bits (1340), Expect = e-147
Identities = 285/708 (40%), Positives = 397/708 (56%), Gaps = 81/708 (11%)
Query: 32 GKPEESRVSSVLEESKRLVDTAMYATMQRNLKKR---GILSPAQLLSFSKLPEPTSGVIA 88
G+ + S V S +EE+K+LVD A Y + ++K+R G SP +LLS+ K P +
Sbjct: 55 GEVDTSLVLSSMEEAKQLVDKA-YKERRESIKQRLRSGSASPMELLSYFKQPVAATRTAV 113
Query: 89 RAAEIMETSIQAMKRKVNLKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLA 148
RAA+ + ++ ++RK+ ++ + TD L+ L++++ SGC + CP
Sbjct: 114 RAADYLHVALDLLERKLRSLWRRPFNVTDVLTPAQLNVLSKSSGCAYQDVGVTCPEQ--- 170
Query: 149 NKYRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREV 208
+KYR ITG CNNR P GASN A RWLP YEDGFS P GW PG NGFP+ R V
Sbjct: 171 DKYRTITGMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALARAV 230
Query: 209 TRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNP 268
+ +++ + +T D S + M WGQ +DHD+ FTP+ ++A+F G +C+ +C Q P
Sbjct: 231 SNEIVRFPTDQLTPDQERSLMFMQWGQLLDHDLDFTPEPAARASFVTGVNCETSCVQQPP 290
Query: 269 CFPIQL-PEEARPAAGTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDAS 327
CFP+++ P + R C+PF+RS AC S R Q+N LTSF+DAS
Sbjct: 291 CFPLKIPPNDPRIKNQADCIPFFRSCPACPG----------SNITIRNQINALTSFVDAS 340
Query: 328 TVYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRG 387
VYGS L R LRN ++ GLL V+ R +D+GRA LPF R
Sbjct: 341 MVYGSEEPLARNLRNMSNQLGLLAVNQRFQDNGRALLPFDNLHDDPCLLTN----RSARI 396
Query: 388 PCFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQI 447
PCFLAGD R+SE+P LT++HTL LREHNRLA LK+LN W + +YQEARK+VGA+ QI
Sbjct: 397 PCFLAGDTRSSEMPELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQI 456
Query: 448 ITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDAS 507
IT RDY+P +LGP A ++Y+ Y Y+ + +P ++NVF T AFR+GH I P + RLD
Sbjct: 457 ITYRDYLPLVLGPTAMRKYLPTYRSYNDSVDPRIANVF-TNAFRYGHTLIQPFMFRLDNR 515
Query: 508 FQEHPDLPGLWLHQAFFSPW---------TLLRG-------------------------- 532
+Q P + L + FF+ W +LRG
Sbjct: 516 YQPMEPNPRVPLSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQ 575
Query: 533 ----------------------GYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYK 570
GYN WR FCGLP+ ET L T + + +A K+++ Y
Sbjct: 576 VMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNLKLARKLMEQYG 635
Query: 571 HPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELE 630
P+NID+W+GG++E + R GPL AC+IG Q + LRDGD FWWEN VF+ QR+ L
Sbjct: 636 TPNNIDIWMGGVSEPLKRKGRVGPLLACIIGTQFRKLRDGDRFWWENEGVFSMQQRQALA 695
Query: 631 KHSLSRVICDNTGLTRVPM-DAFQVGKFPEDFESCDSITGMNLEAWRE 677
+ SL R+ICDNTG+T V + F +P DF +C ++ +NL +WRE
Sbjct: 696 QISLPRIICDNTGITTVSKNNIFMSNSYPRDFVNCSTLPALNLASWRE 743
>gi|4503595 eosinophil peroxidase [Homo sapiens]
Length = 715
Score = 508 bits (1307), Expect = e-143
Identities = 285/708 (40%), Positives = 387/708 (54%), Gaps = 82/708 (11%)
Query: 32 GKPEESRVSSVLEESKRLVDTAMYATMQRNLKKR---GILSPAQLLSFSKLPEPTSGVIA 88
G E S + + E+K LVD A Y Q+++K+R G SP LLS+ K P + +
Sbjct: 29 GAVETSVLRDCIAEAKLLVDAA-YNWTQKSIKQRLRSGSASPMDLLSYFKQPVAATRTVV 87
Query: 89 RAAEIMETSIQAMKRKVNLKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLA 148
RAA+ M ++ ++ K+ + + TD L+E L +++ SGC +C +
Sbjct: 88 RAADYMHVALGLLEEKLQPQRSGPFNVTDVLTEPQLRLLSQASGCALRDQAERC-----S 142
Query: 149 NKYRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREV 208
+KYR ITG CNN+ P GASN ALARWLP YEDG S P GW P NGF LP VR V
Sbjct: 143 DKYRTITGRCNNKRRPLLGASNQALARWLPAEYEDGLSLPFGWTPSRRRNGFLLPLVRAV 202
Query: 209 TRHVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNP 268
+ +++ NE +T D + + M WGQ+IDHD+ F+P+S ++ AF G DC+ TC P
Sbjct: 203 SNQIVRFPNERLTSDRGRALMFMQWGQFIDHDLDFSPESPARVAFTAGVDCERTCAQLPP 262
Query: 269 CFPIQLP-EEARPAAGTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDAS 327
CFPI++P + R C+PF+RS+ +C R Q+N LTSF+DAS
Sbjct: 263 CFPIKIPPNDPRIKNQRDCIPFFRSAPSCPQNKNRV----------RNQINALTSFVDAS 312
Query: 328 TVYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRG 387
VYGS +L +LRN T+ GLL ++ R +D+GRA LPF R
Sbjct: 313 MVYGSEVSLSLRLRNRTNYLGLLAINQRFQDNGRALLPFDNLHDDPCLLTNRS----ARI 368
Query: 388 PCFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQI 447
PCFLAGD R++E P L A+HTL++REHNRLA L+ LN W+ D +Y EARK++GA+ QI
Sbjct: 369 PCFLAGDTRSTETPKLAAMHTLFMREHNRLATELRRLNPRWNGDKLYNEARKIMGAMVQI 428
Query: 448 ITLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDAS 507
IT RD++P +LG ++ +G Y GY S +P V+NVF T AFRFGH + P + RLD+
Sbjct: 429 ITYRDFLPLVLGKARARRTLGHYRGYCSNVDPRVANVF-TLAFRFGHTMLQPFMFRLDSQ 487
Query: 508 FQEHPDLPGLWLHQAFFSPWTL---------LRG-------------------------- 532
++ + L AFF+ W + LRG
Sbjct: 488 YRASAPNSHVPLSSAFFASWRIVYEGGIDPILRGLMATPAKLNRQDAMLVDELRDRLFRQ 547
Query: 533 ----------------------GYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYK 570
GYN WR FCGL + A LS + ++ +A K L+LY
Sbjct: 548 VRRIGLDLAALNMQRSRDHGLPGYNAWRRFCGLSQPRNLAQLSRVLKNQDLARKFLNLYG 607
Query: 571 HPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELE 630
PDNID+W+G +AE LP AR GPL ACL Q + RDGD FWW+ VFT QR+ L
Sbjct: 608 TPDNIDIWIGAIAEPLLPGARVGPLLACLFENQFRRARDGDRFWWQKRGVFTKRQRKALS 667
Query: 631 KHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRET 678
+ SLSR+ICDNTG+T V D F+ +P F +C I +NL AWR T
Sbjct: 668 RISLSRIICDNTGITTVSRDIFRANIYPRGFVNCSRIPRLNLSAWRGT 715
>gi|40549418 lactoperoxidase isoform 1 preproprotein [Homo sapiens]
Length = 712
Score = 452 bits (1163), Expect = e-127
Identities = 275/701 (39%), Positives = 371/701 (52%), Gaps = 87/701 (12%)
Query: 37 SRVSSVLEESKRLVDTAMYATMQRNLKKRGILSPA--QLLSFSKLPEPTSGVIARAAEIM 94
S +S + ++K V+ A + R +P QL + K + + R ++
Sbjct: 32 SAISDTVSQAKVQVNKAFLDSRTRLKTAMSSETPTSRQLSEYLKHAKGRTRTAIRNGQVW 91
Query: 95 ETSIQAMKRKVNLKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLANKYRPI 154
E S++ +++K +L + TD S DL S+ + GC +C + C + YR I
Sbjct: 92 EESLKRLRQKASLT-----NVTDP-SLDLTSLSLEV-GCGAPAPVVRC-DPC--SPYRTI 141
Query: 155 TGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVIQ 214
TG CNNR P GA+N ALARWLP YEDG S P GW PG NGFPLP REV+ ++
Sbjct: 142 TGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVG 201
Query: 215 VSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQL 274
NE D S L M WGQ +DHD+ F P + ++ A C C + CFPI
Sbjct: 202 YLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCFPIMF 261
Query: 275 PEEARPAAGTA--CLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDASTVYGS 332
P P AGT C+PF+R+ C T +L R+Q+N LTSFLDAS VY S
Sbjct: 262 PPND-PKAGTQGKCMPFFRAGFVCPTPPYKSL--------AREQINALTSFLDASFVYSS 312
Query: 333 SPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRGPCFLA 392
P+L +LRN +S GL+ V+ + D G YLP+ + P+ C I R PCFLA
Sbjct: 313 EPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPY-DSKKPSPCE---FINTTARVPCFLA 368
Query: 393 GDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRD 452
GD RASE L HTL+LREHNRLA LK LN W + +YQEARK++GA QIIT RD
Sbjct: 369 GDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRD 428
Query: 453 YIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQE-- 510
Y+P +LG + Q+++ PY+GY + +P +SNVF T AFRFGH + + RLD ++Q
Sbjct: 429 YLPILLG-DHMQKWIPPYQGYSESVDPRISNVF-TFAFRFGHLEVPSSMFRLDENYQPWG 486
Query: 511 -HPDLP------GLW--------------------------------LHQAFFSPWTLLR 531
P+LP W L F P +
Sbjct: 487 PEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIH 546
Query: 532 G-----------------GYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYKHPDN 574
G GYN WR FC L + +T +L+T + S+ +A K+L LY PDN
Sbjct: 547 GFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDN 606
Query: 575 IDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELEKHSL 634
ID+W+G +AE + R R GPL ACL+GKQ + +RDGD FWWEN VFT+ Q+ L+K S
Sbjct: 607 IDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQKMSF 666
Query: 635 SRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAW 675
SR++CDNT +T+VP D F +P DF C +I ++L W
Sbjct: 667 SRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPW 707
>gi|231569458 lactoperoxidase isoform 3 preproprotein [Homo sapiens]
Length = 629
Score = 446 bits (1146), Expect = e-125
Identities = 250/585 (42%), Positives = 322/585 (55%), Gaps = 75/585 (12%)
Query: 151 YRPITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREVTR 210
YR ITG CNNR P GA+N ALARWLP YEDG S P GW PG NGFPLP REV+
Sbjct: 55 YRTITGDCNNRRKPALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSN 114
Query: 211 HVIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCF 270
++ NE D S L M WGQ +DHD+ F P + ++ A C C + CF
Sbjct: 115 KIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCIQGDNCF 174
Query: 271 PIQLPEEARPAAGTA--CLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDAST 328
PI P P AGT C+PF+R+ C T +L R+Q+N LTSFLDAS
Sbjct: 175 PIMFPPND-PKAGTQGKCMPFFRAGFVCPTPPYKSL--------AREQINALTSFLDASF 225
Query: 329 VYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRGP 388
VY S P+L +LRN +S GL+ V+ + D G YLP+ + P+ C I R P
Sbjct: 226 VYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPY-DSKKPSPCE---FINTTARVP 281
Query: 389 CFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQII 448
CFLAGD RASE L HTL+LREHNRLA LK LN W + +YQEARK++GA QII
Sbjct: 282 CFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQII 341
Query: 449 TLRDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASF 508
T RDY+P +LG + Q+++ PY+GY + +P +SNVF T AFRFGH + + RLD ++
Sbjct: 342 TFRDYLPILLG-DHMQKWIPPYQGYSESVDPRISNVF-TFAFRFGHLEVPSSMFRLDENY 399
Query: 509 QE---HPDLP------GLW--------------------------------LHQAFFSPW 527
Q P+LP W L F P
Sbjct: 400 QPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPT 459
Query: 528 TLLRG-----------------GYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYK 570
+ G GYN WR FC L + +T +L+T + S+ +A K+L LY
Sbjct: 460 HRIHGFDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYG 519
Query: 571 HPDNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELE 630
PDNID+W+G +AE + R R GPL ACL+GKQ + +RDGD FWWEN VFT+ Q+ L+
Sbjct: 520 TPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWENPGVFTNEQKDSLQ 579
Query: 631 KHSLSRVICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAW 675
K S SR++CDNT +T+VP D F +P DF C +I ++L W
Sbjct: 580 KMSFSRLVCDNTRITKVPRDPFWANSYPYDFVDCSAIDKLDLSPW 624
>gi|109150416 peroxidasin [Homo sapiens]
Length = 1479
Score = 443 bits (1140), Expect = e-124
Identities = 268/706 (37%), Positives = 376/706 (53%), Gaps = 82/706 (11%)
Query: 39 VSSVLEESKRLVDTAMYATMQRNLKKRGILSPAQLLSFSKLP-EPTSGVIARAAEIMETS 97
V++ + E+ VD A+ +T R SP LL+ + P +P + ARA EI E +
Sbjct: 624 VATSIVEAIATVDRAINSTRTHLFDSRP-RSPNDLLALFRYPRDPYTVEQARAGEIFERT 682
Query: 98 IQAMKRKVNLKTQ-----QSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLANKYR 152
+Q ++ V S H D +S L++IAN+SGC + C + C KYR
Sbjct: 683 LQLIQEHVQHGLMVDLNGTSYHYNDLVSPQYLNLIANLSGCTAHRRVNNCSDMCFHQKYR 742
Query: 153 PITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREVTRHV 212
G CNN HP WGAS TA R L VYE+GF+ PRG NP LYNG LP R V+ +
Sbjct: 743 THDGTCNNLQHPMWGASLTAFERLLKSVYENGFNTPRGINPHRLYNGHALPMPRLVSTTL 802
Query: 213 IQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCFPI 272
I E VT D++++ +LM WGQ++DHD+ T + S+A F G C C N PCF +
Sbjct: 803 I--GTETVTPDEQFTHMLMQWGQFLDHDLDSTVVALSQARFSDGQHCSNVCSNDPPCFSV 860
Query: 273 QLP-EEARPAAGTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDASTVYG 331
+P ++R +G C+ F RSS CG+G L +++ PR+Q+N LTS++DAS VYG
Sbjct: 861 MIPPNDSRARSGARCMFFVRSSPVCGSGMTSLL---MNSVYPREQINQLTSYIDASNVYG 917
Query: 332 SSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRGPCFL 391
S+ R +R+ S GLLR ++ SG+ LPF P C + E+ PCFL
Sbjct: 918 STEHEARSIRDLASHRGLLR-QGIVQRSGKPLLPFATG-PPTECMRDEN---ESPIPCFL 972
Query: 392 AGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLR 451
AGD RA+E LT++HTLW REHNR+A L LN HW D +Y E RK+VGA Q IT +
Sbjct: 973 AGDHRANEQLGLTSMHTLWFREHNRIATELLKLNPHWDGDTIYYETRKIVGAEIQHITYQ 1032
Query: 452 DYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQE- 510
++P+ILG E + +G Y GYD N + N F+TAAFRFGH ++PL+ RLD +FQ
Sbjct: 1033 HWLPKILG-EVGMRTLGEYHGYDPGINAGIFNAFATAAFRFGHTLVNPLLYRLDENFQPI 1091
Query: 511 -HPDLPGLWLHQAFFSPWT---------LLRG---------------------------- 532
LP LH+AFFSP+ LLRG
Sbjct: 1092 AQDHLP---LHKAFFSPFRIVNEGGIDPLLRGLFGVAGKMRVPSQLLNTELTERLFSMAH 1148
Query: 533 --------------------GYNEWREFCGLPRLETPADLSTAIASRSVADKILDLYKHP 572
Y+++R +C L T DL I + + +K+ LY
Sbjct: 1149 TVALDLAAINIQRGRDHGIPPYHDYRVYCNLSAAHTFEDLKNEIKNPEIREKLKRLYGST 1208
Query: 573 DNIDVWLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELEKH 632
NID++ + E+ +P +R GP CL+ Q K LRDGD W+EN VF+ AQ ++++
Sbjct: 1209 LNIDLFPALVVEDLVPGSRLGPTLMCLLSTQFKRLRDGDRLWYENPGVFSPAQLTQIKQT 1268
Query: 633 SLSRVICDNT-GLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRE 677
SL+R++CDN +TRV D F+V +FP + SCD I ++L W++
Sbjct: 1269 SLARILCDNADNITRVQSDVFRVAEFPHGYGSCDEIPRVDLRVWQD 1314
>gi|126517478 peroxidasin homolog-like [Homo sapiens]
Length = 1463
Score = 393 bits (1009), Expect = e-109
Identities = 250/701 (35%), Positives = 353/701 (50%), Gaps = 78/701 (11%)
Query: 40 SSVLEESKRLVDTAMYATMQRNLKKRGILSPAQLLSFSKLPEPTSGVIARAAEIMETSIQ 99
SS+L+ +R VD+A+ +T + ++ S L F +P +ARA EI E ++Q
Sbjct: 612 SSILDAVQR-VDSAINSTRRHLFSQKPHTSSDLLAQFHYPRDPLIVEMARAGEIFEHTLQ 670
Query: 100 AMKRKV------NLKTQQSQHPTDALSEDLLSIIANMSGCLPYMLPPKCPNTCLANKYRP 153
++ +V +L+ ++ ++ D +S LS+IAN+SGC P C N C KYR
Sbjct: 671 LIRERVKQGLTVDLEGKEFRY-NDLVSPRSLSLIANLSGCTARRPLPNCSNRCFHAKYRA 729
Query: 154 ITGACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGWNPGFLYNGFPLPPVREVTRHVI 213
G CNN P WGA+ TA AR L P Y DG PRG + + PLPP R V +
Sbjct: 730 HDGTCNNLQQPTWGAALTAFARLLQPAYRDGIRAPRGLGLP-VGSRQPLPPPRLVA--TV 786
Query: 214 QVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCFPIQ 273
VT D Y+ +LM WG +++HD+ T + S A F G C C N PCFP+
Sbjct: 787 WARAAAVTPDHSYTRMLMHWGWFLEHDLDHTVPALSTARFSDGRPCSSVCTNDPPCFPMN 846
Query: 274 LPEEARPAAGTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDASTVYGSS 333
C+ F RSS AC +G A + + R+Q+N T+++D S VYGSS
Sbjct: 847 TRHADPRGTHAPCMLFARSSPACASGRPSA---TVDSVYAREQINQQTAYIDGSNVYGSS 903
Query: 334 PALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPGETRGPCFLAG 393
+ LR+ + GLL+ SG+ LPF P CA + E PCFLAG
Sbjct: 904 ERESQALRDPSVPRGLLKTGFPWPPSGKPLLPF-STGPPTECARQ-----EQESPCFLAG 957
Query: 394 DGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRDY 453
D RA+E +L A+HTLW REHNR+A L ALN HW + VYQEARK+VGA Q IT +
Sbjct: 958 DHRANEHLALAAMHTLWFREHNRVATELSALNPHWEGNTVYQEARKIVGAELQHITYSHW 1017
Query: 454 IPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDASFQE--- 510
+P++LG + G Y GY+ N + N F+TAAFRFGH I+P++ RL+A+ E
Sbjct: 1018 LPKVLGDPGTRMLRG-YRGYNPNVNAGIINSFATAAFRFGHTLINPILYRLNATLGEISE 1076
Query: 511 ---------------------HPDLPGLW----------------LHQAFFSPW------ 527
P L GL+ L Q FS
Sbjct: 1077 GHLPFHKALFSPSRIIKEGGIDPVLRGLFGVAAKWRAPSYLLSPELTQRLFSAAYSAAVD 1136
Query: 528 ---TLLRGG-------YNEWREFCGLPRLETPADLSTAIASRSVADKILDLYKHPDNIDV 577
T+++ G Y ++R FC L ++ DL I + K+ LY P +ID+
Sbjct: 1137 SAATIIQRGRDHGIPPYVDFRVFCNLTSVKNFEDLQNEIKDSEIRQKLRKLYGSPGDIDL 1196
Query: 578 WLGGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSHVFTDAQRRELEKHSLSRV 637
W + E+ +P R GP CL Q + LRDGD FW+EN VFT AQ +L++ SLSRV
Sbjct: 1197 WPALMVEDLIPGTRVGPTLMCLFVTQFQRLRDGDRFWYENPGVFTPAQLTQLKQASLSRV 1256
Query: 638 ICDN-TGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRE 677
+CDN + +V D F ++P+D+ +C I ++L W++
Sbjct: 1257 LCDNGDSIQQVQADVFVKAEYPQDYLNCSEIPKVDLRVWQD 1297
>gi|20149640 dual oxidase 1 precursor [Homo sapiens]
Length = 1551
Score = 101 bits (251), Expect = 3e-21
Identities = 141/559 (25%), Positives = 211/559 (37%), Gaps = 127/559 (22%)
Query: 156 GACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGW----NPGFLYNGFPLPPVREVTRH 211
G NN RWG+ + L R +P Y DG QP G NP L N P
Sbjct: 34 GWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLGEPHLPNPRDLSNTISRGPAG----- 88
Query: 212 VIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCFP 271
+ + N V L + +G ++ D+ A F + +P F
Sbjct: 89 LASLRNRTV--------LGVFFGYHVLSDLVSVETPGCPAEF-----LNIRIPPGDPMFD 135
Query: 272 IQLPEEARPAAGTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDASTVYG 331
P++ G LPF RS TG S +NPR N +T +LD S +YG
Sbjct: 136 ---PDQR----GDVVLPFQRSRWDPETGR--------SPSNPRDPANQVTGWLDGSAIYG 180
Query: 332 SSPALERQLRNWTSAEGLLRVHARL-RDSGRAYLPFVPPRAPAACAPEPGIPGETRGPCF 390
SS + LR+++ + RDS L + AP+P +
Sbjct: 181 SSHSWSDALRSFSRGQLASGPDPAFPRDSQNPLLMWA--------APDPATGQNGPRGLY 232
Query: 391 LAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITL 450
G R + P L AL LW R HN A L + W + ++Q ARK V A +Q I +
Sbjct: 233 AFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAV 292
Query: 451 RDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLV--RRLDASF 508
+++P L Q+ + Y GY +P++S+ F A+ +F + P V R F
Sbjct: 293 YEWLPSFL-----QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHF 347
Query: 509 Q----------------------EHP-----------------------------DLPGL 517
Q EHP D+
Sbjct: 348 QGVINRNSSVSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAEREDHVLVEDVRDF 407
Query: 518 WLHQAFFSPWT-----LLRG------GYNEWREFCGLPRLETPADLSTAIASRSVADKIL 566
W FS L RG Y + R GL + D++ A++ + D +L
Sbjct: 408 WPGPLKFSRTDHLASCLQRGRDLGLPSYTKARAALGLSPITRWQDINPALSRSN--DTVL 465
Query: 567 DLYKHPDNIDV-WL----GGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSH-- 619
+ N D+ WL GGL E+ GPLF+ ++ +Q LRDGD +W+EN+
Sbjct: 466 EATAALYNQDLSWLELLPGGLLES---HRDPGPLFSTIVLEQFVRLRDGDRYWFENTRNG 522
Query: 620 VFTDAQRRELEKHSLSRVI 638
+F+ + E+ +L V+
Sbjct: 523 LFSKKEIEEIRNTTLQDVL 541
>gi|28872751 dual oxidase 1 precursor [Homo sapiens]
Length = 1551
Score = 101 bits (251), Expect = 3e-21
Identities = 141/559 (25%), Positives = 211/559 (37%), Gaps = 127/559 (22%)
Query: 156 GACNNRDHPRWGASNTALARWLPPVYEDGFSQPRGW----NPGFLYNGFPLPPVREVTRH 211
G NN RWG+ + L R +P Y DG QP G NP L N P
Sbjct: 34 GWYNNLMEHRWGSKGSRLQRLVPASYADGVYQPLGEPHLPNPRDLSNTISRGPAG----- 88
Query: 212 VIQVSNEVVTDDDRYSDLLMAWGQYIDHDIAFTPQSTSKAAFGGGADCQMTCENQNPCFP 271
+ + N V L + +G ++ D+ A F + +P F
Sbjct: 89 LASLRNRTV--------LGVFFGYHVLSDLVSVETPGCPAEF-----LNIRIPPGDPMFD 135
Query: 272 IQLPEEARPAAGTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDASTVYG 331
P++ G LPF RS TG S +NPR N +T +LD S +YG
Sbjct: 136 ---PDQR----GDVVLPFQRSRWDPETGR--------SPSNPRDPANQVTGWLDGSAIYG 180
Query: 332 SSPALERQLRNWTSAEGLLRVHARL-RDSGRAYLPFVPPRAPAACAPEPGIPGETRGPCF 390
SS + LR+++ + RDS L + AP+P +
Sbjct: 181 SSHSWSDALRSFSRGQLASGPDPAFPRDSQNPLLMWA--------APDPATGQNGPRGLY 232
Query: 391 LAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITL 450
G R + P L AL LW R HN A L + W + ++Q ARK V A +Q I +
Sbjct: 233 AFGAERGNREPFLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAV 292
Query: 451 RDYIPRILGPEAFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLV--RRLDASF 508
+++P L Q+ + Y GY +P++S+ F A+ +F + P V R F
Sbjct: 293 YEWLPSFL-----QKTLPEYTGYRPFLDPSISSEFVAASEQFLSTMVPPGVYMRNASCHF 347
Query: 509 Q----------------------EHP-----------------------------DLPGL 517
Q EHP D+
Sbjct: 348 QGVINRNSSVSRALRVCNSYWSREHPSLQSAEDVDALLLGMASQIAEREDHVLVEDVRDF 407
Query: 518 WLHQAFFSPWT-----LLRG------GYNEWREFCGLPRLETPADLSTAIASRSVADKIL 566
W FS L RG Y + R GL + D++ A++ + D +L
Sbjct: 408 WPGPLKFSRTDHLASCLQRGRDLGLPSYTKARAALGLSPITRWQDINPALSRSN--DTVL 465
Query: 567 DLYKHPDNIDV-WL----GGLAENFLPRARTGPLFACLIGKQMKALRDGDWFWWENSH-- 619
+ N D+ WL GGL E+ GPLF+ ++ +Q LRDGD +W+EN+
Sbjct: 466 EATAALYNQDLSWLELLPGGLLES---HRDPGPLFSTIVLEQFVRLRDGDRYWFENTRNG 522
Query: 620 VFTDAQRRELEKHSLSRVI 638
+F+ + E+ +L V+
Sbjct: 523 LFSKKEIEEIRNTTLQDVL 541
>gi|132566532 dual oxidase 2 precursor [Homo sapiens]
Length = 1548
Score = 79.3 bits (194), Expect = 1e-14
Identities = 67/226 (29%), Positives = 98/226 (43%), Gaps = 22/226 (9%)
Query: 283 GTACLPFYRSSAACGTGDQGALFGNLSTANPRQQMNGLTSFLDASTVYGSSPALERQLRN 342
G LPF RS TG S +NPR N +T +LD S +YGSS + LR+
Sbjct: 146 GDVVLPFQRSRWDPETGR--------SPSNPRDLANQVTGWLDGSAIYGSSHSWSDALRS 197
Query: 343 WTSAEGLLRVHARL-RDSGRAYLPFVPPRAPAACAPEPGIPGETRGPCFLAGDGRASEVP 401
++ + RDS L + AP+P + G R + P
Sbjct: 198 FSGGQLASGPDPAFPRDSQNPLLMWA--------APDPATGQNGPRGLYAFGAERGNREP 249
Query: 402 SLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGALHQIITLRDYIPRILGPE 461
L AL LW R HN A L + W + ++Q ARK V A +Q I + +++P L
Sbjct: 250 FLQALGLLWFRYHNLWAQRLARQHPDWEDEELFQHARKRVIATYQNIAVYEWLPSFL--- 306
Query: 462 AFQQYVGPYEGYDSTANPTVSNVFSTAAFRFGHATIHPLVRRLDAS 507
Q+ + Y GY +P++S F A+ +F + P V +AS
Sbjct: 307 --QKTLPEYTGYRPFLDPSISPEFVVASEQFFSTMVPPGVYMRNAS 350
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 72.4 bits (176), Expect = 2e-12
Identities = 39/117 (33%), Positives = 55/117 (47%), Gaps = 7/117 (5%)
Query: 670 MNLEAWRETFPQDDK--CGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQ 727
+N W + P ++ CG P +ENG + + Y C +GY L G ++ CT
Sbjct: 1673 LNQGQWTQPLPHCERISCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTD 1732
Query: 728 EG-WDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
G W+ P C DV+ECA G+ C A C N G + C C PY DG+ C +
Sbjct: 1733 NGSWNGVSPSCLDVDECAVGS--DCSEHASCLNVDGSYICSCVPPYT--GDGKNCAE 1785
Score = 48.1 bits (113), Expect = 3e-05
Identities = 34/107 (31%), Positives = 49/107 (45%), Gaps = 8/107 (7%)
Query: 684 KCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WDFQPPLCKDVNE 742
+C P + NG + + + + C GY L G +LTC +G WD + PLCK VN
Sbjct: 2890 RCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVN- 2948
Query: 743 CA---DGAHPPCHASARCRNTKGGFQCLCADPYEL-GDDGRTCVDSG 785
C D AH + + G Q C Y+L G+ R C+ +G
Sbjct: 2949 CGPPEDLAHGFPNGFSFIHG--GHIQYQCFPGYKLHGNSSRRCLSNG 2993
Score = 47.0 bits (110), Expect = 8e-05
Identities = 22/55 (40%), Positives = 28/55 (50%), Gaps = 1/55 (1%)
Query: 684 KCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WDFQPPLC 737
KC PE++ NG ++ + YSC GY LQG + CT G WD PP C
Sbjct: 1904 KCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPAC 1958
Score = 47.0 bits (110), Expect = 8e-05
Identities = 30/117 (25%), Positives = 47/117 (40%), Gaps = 5/117 (4%)
Query: 675 WRETFP--QDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WD 731
W FP + CG + N V+ YSCR GY +QG L CT++G W
Sbjct: 3052 WSSGFPHCEHTSCGSLPMIPNAFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWS 3111
Query: 732 FQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGR--TCVDSGR 786
P+C+ ++ + + A+ + + C + Y + D TC GR
Sbjct: 3112 QPYPVCEPLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGR 3168
Score = 46.2 bits (108), Expect = 1e-04
Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 685 CGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECA 744
C P+ +ENG + S +++YSC G+++ G TC + GW P C + +C
Sbjct: 2556 CDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESGWSSSIPTCMPI-DCG 2614
Query: 745 DGAHPPCHASARCRNTKGGFQ 765
H + ++ +G F+
Sbjct: 2615 LPPHIDFGDCTKLKDDQGYFE 2635
Score = 46.2 bits (108), Expect = 1e-04
Identities = 34/118 (28%), Positives = 50/118 (42%), Gaps = 10/118 (8%)
Query: 673 EAWRETFPQDDK--CGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGW 730
E W +T + +K CG P VEN ++ YSC GY L+G + C + G
Sbjct: 3402 ETWTQTSAKCEKISCGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGT 3461
Query: 731 DFQPPLCKDVNE--CADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGR 786
PP+C+ V C +G C C +G LC +P + C++ GR
Sbjct: 3462 WTSPPICRAVCRFPCQNGG--ICQRPNACSCPEGWMGRLCEEPICI----LPCLNGGR 3513
Score = 44.7 bits (104), Expect = 4e-04
Identities = 33/107 (30%), Positives = 45/107 (42%), Gaps = 10/107 (9%)
Query: 685 CGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQE-GWDFQPPLCKDVNEC 743
C P V NG + L Y C GY L G E+ TC + WD P+C V
Sbjct: 2775 CKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPV--- 2831
Query: 744 ADGAHPPCHASARCRNTKGGFQ----CLCADPYEL-GDDGRTCVDSG 785
D + PP A+ + R + FQ C + + L G R C+ +G
Sbjct: 2832 -DCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANG 2877
Score = 44.3 bits (103), Expect = 5e-04
Identities = 19/59 (32%), Positives = 31/59 (52%), Gaps = 1/59 (1%)
Query: 684 KCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WDFQPPLCKDVN 741
+C P+ + NG F + + + + YSC G+ L+G LTC + G WD P C ++
Sbjct: 2497 ECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIH 2555
Score = 42.4 bits (98), Expect = 0.002
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 5/70 (7%)
Query: 675 WRETFPQDD----KCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQ-EG 729
W F + CG PES E+G V + + ++Y C GYEL+G + C +
Sbjct: 3227 WEPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQ 3286
Query: 730 WDFQPPLCKD 739
W +CK+
Sbjct: 3287 WSGGVAICKE 3296
Score = 41.2 bits (95), Expect = 0.004
Identities = 34/129 (26%), Positives = 55/129 (42%), Gaps = 15/129 (11%)
Query: 635 SRVICDNTGLTR------VPMDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDK---- 684
SR+ C + G + +D VG + SC ++ G + + + D K
Sbjct: 1726 SRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAE 1785
Query: 685 ---CGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WDFQPPLCKDV 740
C P + ENG + + +SC+ GY+L G ++TC + G W+ P CK V
Sbjct: 1786 PIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAV 1845
Query: 741 NECADGAHP 749
+ C A P
Sbjct: 1846 S-CGKPAIP 1853
Score = 39.7 bits (91), Expect = 0.012
Identities = 24/65 (36%), Positives = 32/65 (49%), Gaps = 4/65 (6%)
Query: 681 QDDKCGFPESVENGDF-VHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WDFQPPLCK 738
++ +C P NG + +G V VYSC GY L+G + CT+ G W PLCK
Sbjct: 3295 KETRCETPLEFLNGKADIENRTTGPNV-VYSCNRGYSLEGPSEAHCTENGTWSHPVPLCK 3353
Query: 739 DVNEC 743
N C
Sbjct: 3354 P-NPC 3357
Score = 39.3 bits (90), Expect = 0.016
Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 12/91 (13%)
Query: 684 KCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WDFQPPLCKDVNE 742
+CG P S+ NG S ++ YSC G+ ++G ++ TC G W P C V+
Sbjct: 2145 RCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVS- 2203
Query: 743 CADGAHPPC-------HASARCRNTKGGFQC 766
C + PP H + R ++ +QC
Sbjct: 2204 CGE---PPKVENGFLEHTTGRIFESEVRYQC 2231
Score = 38.5 bits (88), Expect = 0.028
Identities = 22/77 (28%), Positives = 31/77 (40%), Gaps = 3/77 (3%)
Query: 667 ITGMNLEAWRETFP--QDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLT 724
IT + W P + CG P ENG + + Y C GY L G ++ +
Sbjct: 1827 ITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESS 1886
Query: 725 C-TQEGWDFQPPLCKDV 740
C W PP+C+ V
Sbjct: 1887 CLANSSWSHSPPVCEPV 1903
Score = 37.4 bits (85), Expect = 0.061
Identities = 27/100 (27%), Positives = 44/100 (44%), Gaps = 9/100 (9%)
Query: 685 CGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WDFQPPLCKDVNEC 743
CG P ++++ + R + Y+C+ GY L G + + C +G W C V+ C
Sbjct: 1963 CGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVS-C 2021
Query: 744 ADGAHPPC--HASARCRNTKGGFQCL--CADPYELGDDGR 779
+ PP HAS + G C+D Y L D+ +
Sbjct: 2022 DE---PPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQ 2058
Score = 36.2 bits (82), Expect = 0.14
Identities = 33/94 (35%), Positives = 42/94 (44%), Gaps = 10/94 (10%)
Query: 709 YSCRHGYELQGREQLTCTQEG-WDFQPPLCKDVNECADGAHPPCHASARCRNTKGG--FQ 765
Y+C GYEL G L C ++G W+ P C + EC D P + R T G Q
Sbjct: 2683 YTCNPGYELLGNPVLICQEDGTWNGSAPSCISI-EC-DLPTAPENGFLRFTETSMGSAVQ 2740
Query: 766 CLCADPYEL-GDDGRTCVD----SGRLPRVTWIS 794
C + L G D R C++ SG PR IS
Sbjct: 2741 YSCKPGHILAGSDLRLCLENRKWSGASPRCEAIS 2774
Score = 33.1 bits (74), Expect = 1.2
Identities = 28/104 (26%), Positives = 42/104 (40%), Gaps = 6/104 (5%)
Query: 684 KCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQ-EGWDFQPPLCKDVNE 742
+C P + ENG E S + YSC+ G+ L G + C + W P C+ ++
Sbjct: 2716 ECDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAIS- 2774
Query: 743 CADGAHPPCHASARCRNTK--GGFQCLCADPYEL-GDDGRTCVD 783
+P + S + N C Y L G + RTC D
Sbjct: 2775 -CKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQD 2817
Score = 32.3 bits (72), Expect = 2.0
Identities = 21/72 (29%), Positives = 31/72 (43%), Gaps = 4/72 (5%)
Query: 675 WRETFPQ--DDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-WD 731
W P+ +C PE + NG + +Y+C+ G+EL G C + G W
Sbjct: 2428 WSSPLPECVPVECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWL 2487
Query: 732 FQPPLCKDVNEC 743
P CK + EC
Sbjct: 2488 GGKPTCKAI-EC 2498
Score = 32.0 bits (71), Expect = 2.6
Identities = 19/58 (32%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Query: 684 KCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTC-TQEGWDFQPPLCKDV 740
KC P +EN + + V+ +SC+ G+ LQG L C + W+ P+CK V
Sbjct: 2322 KCPEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIV 2379
Score = 31.6 bits (70), Expect = 3.4
Identities = 19/47 (40%), Positives = 25/47 (53%), Gaps = 4/47 (8%)
Query: 685 CGFPESVENGDFVHCE--ESGRRVLVYSCRHGYELQGREQLTCTQEG 729
CG P ++NG F+ E E G +V + C GYEL G TC + G
Sbjct: 2264 CGKPPPIQNG-FMKGENFEVGSKVQFF-CNEGYELVGDSSWTCQKSG 2308
Score = 30.4 bits (67), Expect = 7.5
Identities = 13/32 (40%), Positives = 18/32 (56%), Gaps = 3/32 (9%)
Query: 738 KDVNECADGAHPPCHASARCRNTKGGFQCLCA 769
K+V+EC PC A C++ F+CLCA
Sbjct: 1344 KNVDECLS---QPCKNGATCKDGANSFRCLCA 1372
>gi|194328809 latent transforming growth factor beta binding protein
3 isoform 1 [Homo sapiens]
Length = 1303
Score = 64.3 bits (155), Expect = 5e-10
Identities = 43/128 (33%), Positives = 59/128 (46%), Gaps = 22/128 (17%)
Query: 657 FPEDFESCDSITGMNLEAWRETFPQD-DKCGFPESVENGDFVHCEESGRRVLVYSCRHGY 715
FP ++ C+ G L+A R +D D+C P S +G CE +C+ GY
Sbjct: 679 FPGHYK-CNCYPGYRLKASRPPVCEDIDECRDPSSCPDGK---CENKPGSFKCIACQPGY 734
Query: 716 ELQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELG 775
QG C+DVNECA+G+ PC + C N G F+C CA Y
Sbjct: 735 RSQGGGA--------------CRDVNECAEGS--PC-SPGWCENLPGSFRCTCAQGYAPA 777
Query: 776 DDGRTCVD 783
DGR+C+D
Sbjct: 778 PDGRSCLD 785
Score = 45.8 bits (107), Expect = 2e-04
Identities = 34/144 (23%), Positives = 56/144 (38%), Gaps = 30/144 (20%)
Query: 638 ICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFV 697
+CDN + P G F C ++G +L R D+C FP + GD +
Sbjct: 794 VCDNGICSNTP------GSF-----QCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCI 842
Query: 698 HCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARC 757
+ S R + C G+ L G + C+D++EC+ C C
Sbjct: 843 NTNGSYRCL----CPQGHRLVGGRK--------------CQDIDECSQDP-SLCLPHGAC 883
Query: 758 RNTKGGFQCLCADPYELGDDGRTC 781
+N +G + C+C + + D C
Sbjct: 884 KNLQGSYVCVCDEGFTPTQDQHGC 907
Score = 42.4 bits (98), Expect = 0.002
Identities = 29/78 (37%), Positives = 34/78 (43%), Gaps = 7/78 (8%)
Query: 711 CRHGYELQGREQLTC-TQEGWDFQPP--LCKDVNECADGAHPPCHASARCRNTKGGFQCL 767
C HG + G +C G+ P C DVNEC A P C NT G + C
Sbjct: 585 CGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECE--AEPCGPGRGICMNTGGSYNCH 642
Query: 768 CADPYEL--GDDGRTCVD 783
C Y L G GR+CVD
Sbjct: 643 CNRGYRLHVGAGGRSCVD 660
Score = 41.6 bits (96), Expect = 0.003
Identities = 46/191 (24%), Positives = 70/191 (36%), Gaps = 25/191 (13%)
Query: 693 NGDFVHCEESGRRVLVYSCRHGY--ELQGREQLTCTQEGWDFQP-------PLCKDVNEC 743
+G+ + C + + +CR+G +G + CT ++ P P DV+EC
Sbjct: 1028 DGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPA-EYSPAQRQCLSPEEMDVDEC 1086
Query: 744 ADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTC----VDSGRLPR---VTWISMS 796
D P RC N G ++C C P+ G GR C + R P V W
Sbjct: 1087 QD---PAACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWSQRG 1143
Query: 797 LAALLIGGFAGLTST---VICRWTRTGTKSTLPISETGGGT--PELRCGKHQAVGTSPQR 851
+ G AG T CR R P G G+ P + + TSP
Sbjct: 1144 EDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLL 1203
Query: 852 AAAQDSEQESA 862
+++S+
Sbjct: 1204 LGKPPRDEDSS 1214
Score = 35.4 bits (80), Expect = 0.23
Identities = 15/46 (32%), Positives = 22/46 (47%), Gaps = 3/46 (6%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCV 782
C+D+NECA P C N G ++C+C + LG C+
Sbjct: 353 CQDINECA---MPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCI 395
Score = 31.6 bits (70), Expect = 3.4
Identities = 29/103 (28%), Positives = 38/103 (36%), Gaps = 20/103 (19%)
Query: 690 SVENGDFVHCEESGRRV-----LVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECA 744
S E+ D C SGR V V C G++L D C D++EC
Sbjct: 1214 SEEDSDECRCV-SGRCVPRPGGAVCECPGGFQL-------------DASRARCVDIDECR 1259
Query: 745 D-GAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGR 786
+ S RC NT G F+C+C + CV R
Sbjct: 1260 ELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQRR 1302
Score = 30.0 bits (66), Expect = 9.8
Identities = 14/49 (28%), Positives = 23/49 (46%), Gaps = 1/49 (2%)
Query: 735 PLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
P +D++EC C +C NT+ G++C C + + CVD
Sbjct: 989 PAHRDIDECMLFGSEICK-EGKCVNTQPGYECYCKQGFYYDGNLLECVD 1036
>gi|18497288 latent transforming growth factor beta binding protein
3 isoform 2 [Homo sapiens]
Length = 1256
Score = 64.3 bits (155), Expect = 5e-10
Identities = 43/128 (33%), Positives = 59/128 (46%), Gaps = 22/128 (17%)
Query: 657 FPEDFESCDSITGMNLEAWRETFPQD-DKCGFPESVENGDFVHCEESGRRVLVYSCRHGY 715
FP ++ C+ G L+A R +D D+C P S +G CE +C+ GY
Sbjct: 679 FPGHYK-CNCYPGYRLKASRPPVCEDIDECRDPSSCPDGK---CENKPGSFKCIACQPGY 734
Query: 716 ELQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELG 775
QG C+DVNECA+G+ PC + C N G F+C CA Y
Sbjct: 735 RSQGGGA--------------CRDVNECAEGS--PC-SPGWCENLPGSFRCTCAQGYAPA 777
Query: 776 DDGRTCVD 783
DGR+C+D
Sbjct: 778 PDGRSCLD 785
Score = 45.8 bits (107), Expect = 2e-04
Identities = 34/144 (23%), Positives = 56/144 (38%), Gaps = 30/144 (20%)
Query: 638 ICDNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFV 697
+CDN + P G F C ++G +L R D+C FP + GD +
Sbjct: 794 VCDNGICSNTP------GSF-----QCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCI 842
Query: 698 HCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARC 757
+ S R + C G+ L G + C+D++EC+ C C
Sbjct: 843 NTNGSYRCL----CPQGHRLVGGRK--------------CQDIDECSQDP-SLCLPHGAC 883
Query: 758 RNTKGGFQCLCADPYELGDDGRTC 781
+N +G + C+C + + D C
Sbjct: 884 KNLQGSYVCVCDEGFTPTQDQHGC 907
Score = 44.7 bits (104), Expect = 4e-04
Identities = 36/137 (26%), Positives = 52/137 (37%), Gaps = 14/137 (10%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPR------V 790
C DV+EC D ++ C C NT+GG++C C P E R C+ + R V
Sbjct: 1034 CVDVDECLDESN--CRNGV-CENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPERRDV 1090
Query: 791 TWISMSLAALLIGGFAGLTST---VICRWTRTGTKSTLPISETGGGT--PELRCGKHQAV 845
W + G AG T CR R P G G+ P + +
Sbjct: 1091 CWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFW 1150
Query: 846 GTSPQRAAAQDSEQESA 862
TSP +++S+
Sbjct: 1151 DTSPLLLGKPPRDEDSS 1167
Score = 42.4 bits (98), Expect = 0.002
Identities = 29/78 (37%), Positives = 34/78 (43%), Gaps = 7/78 (8%)
Query: 711 CRHGYELQGREQLTC-TQEGWDFQPP--LCKDVNECADGAHPPCHASARCRNTKGGFQCL 767
C HG + G +C G+ P C DVNEC A P C NT G + C
Sbjct: 585 CGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECE--AEPCGPGRGICMNTGGSYNCH 642
Query: 768 CADPYEL--GDDGRTCVD 783
C Y L G GR+CVD
Sbjct: 643 CNRGYRLHVGAGGRSCVD 660
Score = 35.4 bits (80), Expect = 0.23
Identities = 15/46 (32%), Positives = 22/46 (47%), Gaps = 3/46 (6%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCV 782
C+D+NECA P C N G ++C+C + LG C+
Sbjct: 353 CQDINECA---MPGVCRHGDCLNNPGSYRCVCPPGHSLGPSRTQCI 395
Score = 31.6 bits (70), Expect = 3.4
Identities = 29/103 (28%), Positives = 38/103 (36%), Gaps = 20/103 (19%)
Query: 690 SVENGDFVHCEESGRRV-----LVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECA 744
S E+ D C SGR V V C G++L D C D++EC
Sbjct: 1167 SEEDSDECRCV-SGRCVPRPGGAVCECPGGFQL-------------DASRARCVDIDECR 1212
Query: 745 D-GAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGR 786
+ S RC NT G F+C+C + CV R
Sbjct: 1213 ELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVPQRR 1255
Score = 30.0 bits (66), Expect = 9.8
Identities = 14/49 (28%), Positives = 23/49 (46%), Gaps = 1/49 (2%)
Query: 735 PLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
P +D++EC C +C NT+ G++C C + + CVD
Sbjct: 989 PAHRDIDECMLFGSEICK-EGKCVNTQPGYECYCKQGFYYDGNLLECVD 1036
>gi|4506265 prostaglandin-endoperoxide synthase 2 precursor [Homo
sapiens]
Length = 604
Score = 56.6 bits (135), Expect = 1e-07
Identities = 40/142 (28%), Positives = 63/142 (44%), Gaps = 9/142 (6%)
Query: 318 NGLTSFLDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAP 377
NGL +D + +YG + A +R+LR + + ++ G Y P V P
Sbjct: 208 NGLGHGVDLNHIYGETLARQRKLRLFKDGKMKYQII-----DGEMYPPTVKDTQAEMIYP 262
Query: 378 EPGIPGETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEA 437
P +P R F G VP L T+WLREHNR+ LK + W + ++Q +
Sbjct: 263 -PQVPEHLR---FAVGQEVFGLVPGLMMYATIWLREHNRVCDVLKQEHPEWGDEQLFQTS 318
Query: 438 RKVVGALHQIITLRDYIPRILG 459
R ++ I + DY+ + G
Sbjct: 319 RLILIGETIKIVIEDYVQHLSG 340
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 54.7 bits (130), Expect = 4e-07
Identities = 25/47 (53%), Positives = 30/47 (63%), Gaps = 1/47 (2%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C DV+ECA G C + +C NT G FQC C + YE+ DGRTCVD
Sbjct: 1928 CIDVDECASGNGNLCR-NGQCINTVGSFQCQCNEGYEVAPDGRTCVD 1973
Score = 52.8 bits (125), Expect = 1e-06
Identities = 46/170 (27%), Positives = 67/170 (39%), Gaps = 37/170 (21%)
Query: 638 ICDNTGLTRVP-------MDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDKCGFPES 690
ICD T +P D F ED ++C + +L P G E+
Sbjct: 1248 ICDGGQCTNIPGEYRCLCYDGFMAS---EDMKTCVDVNECDLN------PNICLSGTCEN 1298
Query: 691 VENGDFVHCEE--SGRR-----VLVYSCRHGYELQGREQLTCTQE----------GWDFQ 733
+ HC+ SG++ + C G G+ + CT GW
Sbjct: 1299 TKGSFICHCDMGYSGKKGKTGCTDINECEIGAHNCGKHAV-CTNTAGSFKCSCSPGWIGD 1357
Query: 734 PPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C D++EC++G H C A C+NT G ++CLC + Y DG TC D
Sbjct: 1358 GIKCTDLDECSNGTHM-CSQHADCKNTMGSYRCLCKEGYT--GDGFTCTD 1404
Score = 51.2 bits (121), Expect = 4e-06
Identities = 28/89 (31%), Positives = 42/89 (47%), Gaps = 6/89 (6%)
Query: 695 DFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHAS 754
D C R+ +C++ L G + C G+ Q C+D++EC + P A
Sbjct: 1973 DINECLLEPRKCAPGTCQN---LDGSYRCICPP-GYSLQNEKCEDIDECVE--EPEICAL 2026
Query: 755 ARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C NT+G F+CLC + + L GR C D
Sbjct: 2027 GTCSNTEGSFKCLCPEGFSLSSSGRRCQD 2055
Score = 51.2 bits (121), Expect = 4e-06
Identities = 34/98 (34%), Positives = 46/98 (46%), Gaps = 6/98 (6%)
Query: 711 CRHGYELQGREQLTCT-QEGW--DFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCL 767
CR+G + R C + G+ D C D+NEC + A PC+ C+NT+G +QC
Sbjct: 2413 CRNGECVNDRGSYHCICKTGYTPDITGTSCVDLNEC-NQAPKPCNFI--CKNTEGSYQCS 2469
Query: 768 CADPYELGDDGRTCVDSGRLPRVTWISMSLAALLIGGF 805
C Y L +DGR+C D L IGGF
Sbjct: 2470 CPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTIGGF 2507
Score = 50.4 bits (119), Expect = 7e-06
Identities = 37/127 (29%), Positives = 55/127 (43%), Gaps = 34/127 (26%)
Query: 683 DKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGRE--------------------- 721
D+C P+ ++G ++ + S R C GY L G E
Sbjct: 2129 DECKEPDVCKHGQCINTDGSYR----CECPFGYILAGNECVDTDECSVGNPCGNGTCKNV 2184
Query: 722 ----QLTCTQEGWDFQPPL-CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGD 776
+ TC +EG++ P + C+D+NECA P + RC NT G ++C C Y L +
Sbjct: 2185 IGGFECTC-EEGFEPGPMMTCEDINECAQN---PLLCAFRCVNTYGSYECKCPVGYVLRE 2240
Query: 777 DGRTCVD 783
D R C D
Sbjct: 2241 DRRMCKD 2247
Score = 47.8 bits (112), Expect = 5e-05
Identities = 18/48 (37%), Positives = 25/48 (52%)
Query: 736 LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
+CKD +EC +G H C+N G + C+C Y+ DG CVD
Sbjct: 2244 MCKDEDECEEGKHDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVD 2291
Score = 45.8 bits (107), Expect = 2e-04
Identities = 21/48 (43%), Positives = 27/48 (56%), Gaps = 3/48 (6%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 784
CKD+NEC P + RC NT G ++C C +G DGR CVD+
Sbjct: 611 CKDINECET---PGICMNGRCVNTDGSYRCECFPGLAVGLDGRVCVDT 655
Score = 44.7 bits (104), Expect = 4e-04
Identities = 23/68 (33%), Positives = 36/68 (52%), Gaps = 5/68 (7%)
Query: 718 QGREQLTCTQEGWDFQPPL--CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELG 775
+G + +C Q G+ P C D++EC D +P +C N G ++CLC D +
Sbjct: 1216 EGSYECSC-QPGFALMPDQRSCTDIDECED--NPNICDGGQCTNIPGEYRCLCYDGFMAS 1272
Query: 776 DDGRTCVD 783
+D +TCVD
Sbjct: 1273 EDMKTCVD 1280
Score = 42.7 bits (99), Expect = 0.001
Identities = 33/124 (26%), Positives = 49/124 (39%), Gaps = 29/124 (23%)
Query: 664 CDSITGMNLEAWRETFPQDD----KCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQG 719
C+ G L+ E D+ C E + N C+ CR GY+
Sbjct: 474 CECNKGFQLDLRGECIDVDECEKNPCAGGECINNQGSYTCQ----------CRAGYQ--- 520
Query: 720 REQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGR 779
LT T+ C+D++EC C+ + RC NT G F C+C + + DG+
Sbjct: 521 -STLTRTE---------CRDIDECLQNGRI-CN-NGRCINTDGSFHCVCNAGFHVTRDGK 568
Query: 780 TCVD 783
C D
Sbjct: 569 NCED 572
Score = 41.6 bits (96), Expect = 0.003
Identities = 19/49 (38%), Positives = 24/49 (48%), Gaps = 2/49 (4%)
Query: 735 PLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
P KD+NEC P +CRNT G F+C C + L + R C D
Sbjct: 1024 PFFKDINECK--MIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTD 1070
Score = 41.2 bits (95), Expect = 0.004
Identities = 17/45 (37%), Positives = 25/45 (55%), Gaps = 2/45 (4%)
Query: 739 DVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
D+NECA P + C N +G ++C+C YE+ G+ CVD
Sbjct: 723 DINECA--LDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVD 765
Score = 40.8 bits (94), Expect = 0.006
Identities = 35/113 (30%), Positives = 48/113 (42%), Gaps = 14/113 (12%)
Query: 680 PQDDKCGFPESVENG-----DFVHCEESGRRVLVYSCRHG--YELQGREQLTCTQEGWDF 732
P D +C E E+G + + +E R L+ CR G + +G + C G
Sbjct: 1090 PGDFECKCDEGYESGFMMMKNCMDIDECQRDPLL--CRGGVCHNTEGSYRCECPP-GHQL 1146
Query: 733 QPPL--CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
P + C D+NEC AH + RC N G +QC C Y D CVD
Sbjct: 1147 SPNISACIDINECELSAH--LCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVD 1197
Score = 40.4 bits (93), Expect = 0.007
Identities = 16/44 (36%), Positives = 25/44 (56%), Gaps = 2/44 (4%)
Query: 736 LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGR 779
+C+D++EC +G P C +A C NT G ++C C Y G+
Sbjct: 1805 VCEDIDECQNG--PVCQRNAECINTAGSYRCDCKPGYRFTSTGQ 1846
Score = 39.3 bits (90), Expect = 0.016
Identities = 20/48 (41%), Positives = 23/48 (47%), Gaps = 3/48 (6%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 784
C DVNEC D P S C NT G + C C +EL CVD+
Sbjct: 1485 CTDVNECLD---PTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVDT 1529
Score = 38.5 bits (88), Expect = 0.028
Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Query: 736 LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
+ +D++EC + P +C NT G FQC C Y L +D R C D
Sbjct: 1603 ILEDIDECQE--LPGLCQGGKCINTFGSFQCRCPTGYYLNEDTRVCDD 1648
Score = 38.1 bits (87), Expect = 0.036
Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C+D++EC+ C + C N G F+C+C ++L DGR C D
Sbjct: 570 CEDMDECS--IRNMC-LNGMCINEDGSFKCICKPGFQLASDGRYCKD 613
Score = 38.1 bits (87), Expect = 0.036
Identities = 17/47 (36%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C+D++EC P + C NT+G F+C C L GR C+D
Sbjct: 908 CEDIDECE--VFPGVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLD 952
Score = 38.1 bits (87), Expect = 0.036
Identities = 18/51 (35%), Positives = 23/51 (45%), Gaps = 3/51 (5%)
Query: 736 LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGR 786
+C DVNEC P C NT G + C+C Y + G C+D R
Sbjct: 1645 VCDDVNECET---PGICGPGTCYNTVGNYTCICPPDYMQVNGGNNCMDMRR 1692
Score = 37.4 bits (85), Expect = 0.061
Identities = 18/53 (33%), Positives = 25/53 (47%), Gaps = 2/53 (3%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPR 789
C D NEC + P + +C +T G F CLC ++ DD C+D R
Sbjct: 1847 CNDRNECQE--IPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDINECER 1897
Score = 36.6 bits (83), Expect = 0.10
Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 1/47 (2%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C D NEC + C + C+NT G F C C + L G +C D
Sbjct: 2522 CIDNNECTSDINL-CGSKGICQNTPGSFTCECQRGFSLDQTGSSCED 2567
Score = 36.6 bits (83), Expect = 0.10
Identities = 17/36 (47%), Positives = 21/36 (58%), Gaps = 3/36 (8%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPY 772
C+D+NEC A PC S C NT+GG+ C C Y
Sbjct: 2646 CQDINECGS-AQAPC--SYGCSNTEGGYLCGCPPGY 2678
Score = 36.2 bits (82), Expect = 0.14
Identities = 18/66 (27%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 727 QEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTC--VDS 784
+EG+ C D++EC++ + + +C N GG++C C + DG+ C +D
Sbjct: 1392 KEGYTGDGFTCTDLDECSENLN--LCGNGQCLNAPGGYRCECDMGFVPSADGKACEDIDE 1449
Query: 785 GRLPRV 790
LP +
Sbjct: 1450 CSLPNI 1455
Score = 35.8 bits (81), Expect = 0.18
Identities = 17/47 (36%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C+DV+EC A P C NT G F+C C ++L + + C D
Sbjct: 244 CQDVDECQ--AIPGLCQGGNCINTVGSFECKCPAGHKLNEVSQKCED 288
Score = 35.4 bits (80), Expect = 0.23
Identities = 17/47 (36%), Positives = 23/47 (48%), Gaps = 2/47 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C D+NEC + + +CRNT G F C C + D +TC D
Sbjct: 763 CVDINECV--LNSLLCDNGQCRNTPGSFVCTCPKGFIYKPDLKTCED 807
Score = 35.4 bits (80), Expect = 0.23
Identities = 16/48 (33%), Positives = 23/48 (47%), Gaps = 2/48 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 784
C D NEC P + RC NT+G + C C D + + C+D+
Sbjct: 2289 CVDENECQ--TKPGICENGRCLNTRGSYTCECNDGFTASPNQDECLDN 2334
Score = 35.0 bits (79), Expect = 0.30
Identities = 27/93 (29%), Positives = 41/93 (44%), Gaps = 13/93 (13%)
Query: 695 DFVHCEESGRRVLVYSCRHG--YELQGREQLTCTQEGWDFQPP--LCKDVNECADGAHPP 750
D CE S + C +G L G+ Q C G+ P C D++EC+ +
Sbjct: 1155 DINECELSA-----HLCPNGRCVNLIGKYQCACNP-GYHSTPDRLFCVDIDECSI-MNGG 1207
Query: 751 CHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C C N++G ++C C + L D R+C D
Sbjct: 1208 CETF--CTNSEGSYECSCQPGFALMPDQRSCTD 1238
Score = 35.0 bits (79), Expect = 0.30
Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 3/47 (6%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C+D++EC+ P C N G F+C C YEL G C D
Sbjct: 1444 CEDIDECS---LPNICVFGTCHNLPGLFRCECEIGYELDRSGGNCTD 1487
Score = 34.7 bits (78), Expect = 0.40
Identities = 21/77 (27%), Positives = 36/77 (46%), Gaps = 7/77 (9%)
Query: 711 CRHGYELQGREQLTCT-QEGWDFQPPL--CKDVNECADGAHPPCHASARCRNTKGGFQCL 767
C +G CT +G+ ++P L C+D++EC PC + C+N+ G F C
Sbjct: 776 CDNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESS---PC-INGVCKNSPGSFICE 831
Query: 768 CADPYELGDDGRTCVDS 784
C+ L C+++
Sbjct: 832 CSSESTLDPTKTICIET 848
Score = 34.7 bits (78), Expect = 0.40
Identities = 25/75 (33%), Positives = 33/75 (44%), Gaps = 18/75 (24%)
Query: 710 SCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCA 769
SC GY LQ ++G CKD++ECA H + C NT GGF C C
Sbjct: 2469 SCPKGYILQ--------EDGRS-----CKDLDECATKQH---NCQFLCVNTIGGFTCKC- 2511
Query: 770 DPYELGDDGRTCVDS 784
P +C+D+
Sbjct: 2512 -PPGFTQHHTSCIDN 2525
Score = 34.7 bits (78), Expect = 0.40
Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 7/88 (7%)
Query: 699 CEESGRRVLVYSCRHGYE-LQGREQLTCTQEGW--DFQPPLCKDVNECADGAHPPCHASA 755
CE+ + C+HG + + G + +C Q G+ +Q C D NEC AH A
Sbjct: 2565 CEDVDECEGNHRCQHGCQNIIGGYRCSCPQ-GYLQHYQWNQCVDENECLS-AH--ICGGA 2620
Query: 756 RCRNTKGGFQCLCADPYELGDDGRTCVD 783
C NT G ++C+C ++ C D
Sbjct: 2621 SCHNTLGSYKCMCPAGFQYEQFSGGCQD 2648
Score = 34.3 bits (77), Expect = 0.52
Identities = 23/84 (27%), Positives = 35/84 (41%), Gaps = 13/84 (15%)
Query: 711 CRHGYELQGREQLTCT--------QEGWD---FQPPLCKDVNECADGAHPPCHASARCRN 759
CR +L GR Q T EG++ C D++EC P C N
Sbjct: 1074 CRISPDLCGRGQCVNTPGDFECKCDEGYESGFMMMKNCMDIDECQ--RDPLLCRGGVCHN 1131
Query: 760 TKGGFQCLCADPYELGDDGRTCVD 783
T+G ++C C ++L + C+D
Sbjct: 1132 TEGSYRCECPPGHQLSPNISACID 1155
Score = 33.5 bits (75), Expect = 0.89
Identities = 14/47 (29%), Positives = 21/47 (44%), Gaps = 2/47 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C+D++EC+ P C NT + C C + DG C+D
Sbjct: 286 CEDIDECS--TIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCID 330
Score = 33.5 bits (75), Expect = 0.89
Identities = 18/48 (37%), Positives = 24/48 (50%), Gaps = 5/48 (10%)
Query: 736 LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
+C D+NEC A C + CRNT G F C C + L + C+D
Sbjct: 1888 MCLDINECERDA---C-GNGTCRNTIGSFNCRCNHGFILSHN-NDCID 1930
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 52.4 bits (124), Expect = 2e-06
Identities = 50/168 (29%), Positives = 70/168 (41%), Gaps = 16/168 (9%)
Query: 628 ELEKHSLSRVICDNT--GLTRVPMDAFQVGKFPE--DFESCDSITGM---NLEAWRETFP 680
E E+H C NT + F++ + D + C S G N + E
Sbjct: 1937 ECERHPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSSFFGQVCRNGRCFNEI-- 1994
Query: 681 QDDKCGFPESVE-NGDFVHCEESGRRV-LVYSCRHG--YELQGREQLTCTQEGWDFQPPL 736
KC E E D +C ++ V L SC G L+G + C G++ +
Sbjct: 1995 GSFKCLCNEGYELTPDGKNCIDTNECVALPGSCSPGTCQNLEGSFRCICPP-GYEVKSEN 2053
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 784
C D+NEC + P C NT GGFQCLC + L D+GR C D+
Sbjct: 2054 CIDINECDED--PNICLFGSCTNTPGGFQCLCPPGFVLSDNGRRCFDT 2099
Score = 49.7 bits (117), Expect = 1e-05
Identities = 39/151 (25%), Positives = 61/151 (40%), Gaps = 24/151 (15%)
Query: 640 DNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHC 699
D TG+ V D +G P +C ++ G +C E E G ++C
Sbjct: 2205 DYTGVRCVDTDECSIGN-PCGNGTCTNVIG------------SFECNCNEGFEPGPMMNC 2251
Query: 700 EESGR-----RVLVYSCRHGYELQGREQLTCTQEGWDFQPP--LCKDVNECADGAHPPCH 752
E+ + + C + + G + TC G+ + +CKD++ECA+G H
Sbjct: 2252 EDINECAQNPLLCAFRCMNTF---GSYECTCPI-GYALREDQKMCKDLDECAEGLHDCES 2307
Query: 753 ASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C+N G F C+C DG CVD
Sbjct: 2308 RGMMCKNLIGTFMCICPPGMARRPDGEGCVD 2338
Score = 48.5 bits (114), Expect = 3e-05
Identities = 24/67 (35%), Positives = 39/67 (58%), Gaps = 4/67 (5%)
Query: 717 LQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGD 776
+ G + +C +EGW C D++EC++G H C +A+C NT G ++C C++ +
Sbjct: 1387 IPGSFKCSC-REGWIGNGIKCIDLDECSNGTHQ-CSINAQCVNTPGSYRCACSEGFT--G 1442
Query: 777 DGRTCVD 783
DG TC D
Sbjct: 1443 DGFTCSD 1449
Score = 46.6 bits (109), Expect = 1e-04
Identities = 24/75 (32%), Positives = 34/75 (45%), Gaps = 3/75 (4%)
Query: 731 DFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRV 790
D C D++EC+ P + C+NT+G +QC C Y L +DG+TC D
Sbjct: 2483 DISGTSCIDLDECSQSPKP---CNYICKNTEGSYQCSCPRGYVLQEDGKTCKDLDECQTK 2539
Query: 791 TWISMSLAALLIGGF 805
L +GGF
Sbjct: 2540 QHNCQFLCVNTLGGF 2554
Score = 44.7 bits (104), Expect = 4e-04
Identities = 20/47 (42%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C D++EC + RC NT G FQC+C +EL DG+ CVD
Sbjct: 573 CIDIDECIQNG--VLCKNGRCVNTDGSFQCICNAGFELTTDGKNCVD 617
Score = 44.7 bits (104), Expect = 4e-04
Identities = 34/123 (27%), Positives = 55/123 (44%), Gaps = 25/123 (20%)
Query: 664 CDSITGMNLEAWRETFPQDDKCGFPESV-ENGDFVHCEESGRRVLVYSCRHGYELQGREQ 722
CD G L RE ++C +++ NG V+ + + SC GY Q
Sbjct: 1183 CDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQ----CSCNPGY------Q 1232
Query: 723 LTCTQEGWDFQPPLCKDVNECA--DGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRT 780
T ++G C D++EC +G +C N++G ++C C++ Y L DGR+
Sbjct: 1233 ATPDRQG-------CTDIDECMIMNGG-----CDTQCTNSEGSYECSCSEGYALMPDGRS 1280
Query: 781 CVD 783
C D
Sbjct: 1281 CAD 1283
Score = 43.5 bits (101), Expect = 9e-04
Identities = 20/47 (42%), Positives = 25/47 (53%), Gaps = 2/47 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C+DVNEC P + RC N+KG F C C + L GR C+D
Sbjct: 953 CEDVNECE--VFPGVCPNGRCVNSKGSFHCECPEGLTLDGTGRVCLD 997
Score = 43.1 bits (100), Expect = 0.001
Identities = 21/59 (35%), Positives = 30/59 (50%), Gaps = 6/59 (10%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRVTWISM 795
C+D+NEC PC + CRN G F C C+ +L G C+DS L W+++
Sbjct: 850 CEDINECESN---PC-VNGACRNNLGSFNCECSPGSKLSSTGLICIDS--LKGTCWLNI 902
Score = 42.4 bits (98), Expect = 0.002
Identities = 20/49 (40%), Positives = 25/49 (51%), Gaps = 2/49 (4%)
Query: 735 PLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
P KD+NEC A P +CRNT G F+C C + L + R C D
Sbjct: 1069 PFYKDINECK--AFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTD 1115
Score = 42.0 bits (97), Expect = 0.002
Identities = 21/68 (30%), Positives = 36/68 (52%), Gaps = 5/68 (7%)
Query: 718 QGREQLTCTQEGWDFQPP--LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELG 775
+G + +C+ EG+ P C D++EC + +P +C N G ++CLC D +
Sbjct: 1261 EGSYECSCS-EGYALMPDGRSCADIDECEN--NPDICDGGQCTNIPGEYRCLCYDGFMAS 1317
Query: 776 DDGRTCVD 783
D +TC+D
Sbjct: 1318 MDMKTCID 1325
Score = 41.6 bits (96), Expect = 0.003
Identities = 18/46 (39%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
Query: 738 KDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
+D+NECA P A+ C N +G ++C C YE GR C+D
Sbjct: 767 RDINECA--LDPDICANGICENLRGSYRCNCNSGYEPDASGRNCID 810
Score = 41.6 bits (96), Expect = 0.003
Identities = 18/48 (37%), Positives = 32/48 (66%), Gaps = 2/48 (4%)
Query: 736 LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
+C+D++EC++G + C +A C N+ G ++C CA ++L +G CVD
Sbjct: 1847 VCEDIDECSNGDNL-CQRNADCINSPGSYRCECAAGFKLSPNG-ACVD 1892
Score = 41.2 bits (95), Expect = 0.004
Identities = 17/48 (35%), Positives = 25/48 (52%), Gaps = 2/48 (4%)
Query: 736 LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
+C+D++EC AHP C NT G + C+C Y + G C+D
Sbjct: 1689 ICEDIDECF--AHPGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMD 1734
Score = 40.8 bits (94), Expect = 0.006
Identities = 19/48 (39%), Positives = 26/48 (54%), Gaps = 3/48 (6%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 784
C DV+EC P + C N++G F+C C +G DGR CVD+
Sbjct: 656 CTDVDECQT---PGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDT 700
Score = 39.3 bits (90), Expect = 0.016
Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 3/48 (6%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 784
C D++ECAD P + C NT G ++C C ++L G CVD+
Sbjct: 1530 CTDIDECAD---PINCVNGLCVNTPGRYECNCPPDFQLNPTGVGCVDN 1574
Score = 38.9 bits (89), Expect = 0.021
Identities = 19/47 (40%), Positives = 26/47 (55%), Gaps = 2/47 (4%)
Query: 738 KDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 784
+DVNEC + P ++ +C NT G F+C C Y L G CVD+
Sbjct: 2170 EDVNECLES--PGICSNGQCINTDGSFRCECPMGYNLDYTGVRCVDT 2214
Score = 38.5 bits (88), Expect = 0.028
Identities = 20/47 (42%), Positives = 27/47 (57%), Gaps = 3/47 (6%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C DV+EC GAH C A C N G F+C C + + +G +G C+D
Sbjct: 1365 CTDVDECEIGAHN-CDMHASCLNIPGSFKCSCREGW-IG-NGIKCID 1408
Score = 38.5 bits (88), Expect = 0.028
Identities = 23/67 (34%), Positives = 30/67 (44%), Gaps = 6/67 (8%)
Query: 721 EQLTCTQEGWDFQPP----LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGD 776
E T G F+P + +D++EC + P C NT G FQC C Y L +
Sbjct: 1628 EYYTLCPGGEGFRPNPITIILEDIDECQE--LPGLCQGGNCINTFGSFQCECPQGYYLSE 1685
Query: 777 DGRTCVD 783
D R C D
Sbjct: 1686 DTRICED 1692
Score = 38.5 bits (88), Expect = 0.028
Identities = 26/90 (28%), Positives = 41/90 (45%), Gaps = 7/90 (7%)
Query: 697 VHCEESGRRVLVYSCRHGYE-LQGREQLTCTQEGW--DFQPPLCKDVNECADGAHPPCHA 753
++CE+ + C+HG + + G + C Q G+ +Q C D NEC++ P
Sbjct: 2610 LNCEDVDECDGNHRCQHGCQNILGGYRCGCPQ-GYIQHYQWNQCVDENECSN---PNACG 2665
Query: 754 SARCRNTKGGFQCLCADPYELGDDGRTCVD 783
SA C NT G ++C C + C D
Sbjct: 2666 SASCYNTLGSYKCACPSGFSFDQFSSACHD 2695
Score = 38.1 bits (87), Expect = 0.036
Identities = 16/47 (34%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C+D++EC+ P + C NT G + C+C Y DG C+D
Sbjct: 316 CEDIDECS--IIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCID 360
Score = 38.1 bits (87), Expect = 0.036
Identities = 20/48 (41%), Positives = 23/48 (47%), Gaps = 3/48 (6%)
Query: 737 CKDVNECADGAHPP-CHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C D NEC G+ P C A C+NT G F C C + L G C D
Sbjct: 2569 CIDNNEC--GSQPSLCGAKGICQNTPGSFSCECQRGFSLDATGLNCED 2614
Score = 37.4 bits (85), Expect = 0.061
Identities = 17/47 (36%), Positives = 22/47 (46%), Gaps = 3/47 (6%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C+D++EC+ C N G F C+C D YEL G C D
Sbjct: 1489 CQDIDECS---FQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCTD 1532
Score = 37.0 bits (84), Expect = 0.080
Identities = 18/47 (38%), Positives = 23/47 (48%), Gaps = 2/47 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C D++EC +P C NT+G FQC C +EL CVD
Sbjct: 1156 CMDIDECE--RNPLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVD 1200
Score = 36.6 bits (83), Expect = 0.10
Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 9/94 (9%)
Query: 684 KCGFPES-VENGDFVHCEESGRRVLVYSCRHG--YELQGREQLTCTQEGWDFQP--PLCK 738
+CG P+ +++ + C + +C Y G + C G+ F C
Sbjct: 2636 RCGCPQGYIQHYQWNQCVDENECSNPNACGSASCYNTLGSYKCACPS-GFSFDQFSSACH 2694
Query: 739 DVNECADGAHPPCHASARCRNTKGGFQCLCADPY 772
DVNEC+ +P + C NT+GG+ C C Y
Sbjct: 2695 DVNECSSSKNP---CNYGCSNTEGGYLCGCPPGY 2725
Score = 35.8 bits (81), Expect = 0.18
Identities = 20/65 (30%), Positives = 32/65 (49%), Gaps = 3/65 (4%)
Query: 719 GREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDG 778
G + C+ EG+ C DV+ECA+ + C + +C N G ++C C + D
Sbjct: 1430 GSYRCACS-EGFTGDGFTCSDVDECAENINL-CE-NGQCLNVPGAYRCECEMGFTPASDS 1486
Query: 779 RTCVD 783
R+C D
Sbjct: 1487 RSCQD 1491
Score = 35.4 bits (80), Expect = 0.23
Identities = 17/45 (37%), Positives = 22/45 (48%), Gaps = 2/45 (4%)
Query: 731 DFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELG 775
D + C D++EC P S C NT G F+C C + YE G
Sbjct: 1107 DMEERNCTDIDECR--ISPDLCGSGICVNTPGSFECECFEGYESG 1149
Score = 35.0 bits (79), Expect = 0.30
Identities = 15/46 (32%), Positives = 23/46 (50%), Gaps = 2/46 (4%)
Query: 738 KDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
+D++EC P + +C NT G F+C C Y G +C+D
Sbjct: 2448 RDIDECK--VMPNLCTNGQCINTMGSFRCFCKVGYTTDISGTSCID 2491
Score = 33.9 bits (76), Expect = 0.68
Identities = 24/75 (32%), Positives = 31/75 (41%), Gaps = 18/75 (24%)
Query: 710 SCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCA 769
SC GY LQ ++G CKD++EC H + C NT GGF C C
Sbjct: 2516 SCPRGYVLQ--------EDG-----KTCKDLDECQTKQH---NCQFLCVNTLGGFTCKC- 2558
Query: 770 DPYELGDDGRTCVDS 784
P C+D+
Sbjct: 2559 -PPGFTQHHTACIDN 2572
Score = 33.5 bits (75), Expect = 0.89
Identities = 16/47 (34%), Positives = 23/47 (48%), Gaps = 2/47 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C+DV+EC A P C NT G F+C C ++ + + C D
Sbjct: 274 CQDVDECQ--AIPGICQGGNCINTVGSFECRCPAGHKQSETTQKCED 318
Score = 32.7 bits (73), Expect = 1.5
Identities = 15/47 (31%), Positives = 20/47 (42%), Gaps = 9/47 (19%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C N C +G C N G F+C+C + L +GR C D
Sbjct: 621 CTTTNMCLNGM---------CINEDGSFKCICKPGFVLAPNGRYCTD 658
Score = 32.7 bits (73), Expect = 1.5
Identities = 14/47 (29%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C D NEC + + H C + +G +QC+C + ++ D C+D
Sbjct: 1890 CVDRNECLEIPNVCSHGL--CVDLQGSYQCICHNGFKASQDQTMCMD 1934
Score = 32.0 bits (71), Expect = 2.6
Identities = 15/47 (31%), Positives = 21/47 (44%), Gaps = 2/47 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C D++EC + + CRNT G + C C Y + TC D
Sbjct: 808 CIDIDECL--VNRLLCDNGLCRNTPGSYSCTCPPGYVFRTETETCED 852
Score = 31.6 bits (70), Expect = 3.4
Identities = 15/47 (31%), Positives = 22/47 (46%), Gaps = 4/47 (8%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C DV+EC PC + C NT G + C C ++ + C+D
Sbjct: 533 CIDVDECTSN---PC-TNGDCVNTPGSYYCKCHAGFQRTPTKQACID 575
Score = 30.8 bits (68), Expect = 5.7
Identities = 17/47 (36%), Positives = 20/47 (42%), Gaps = 2/47 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C DVNEC ++ C NTKG F C C Y + C D
Sbjct: 1323 CIDVNECDLNSN--ICMFGECENTKGSFICHCQLGYSVKKGTTGCTD 1367
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 52.4 bits (124), Expect = 2e-06
Identities = 30/82 (36%), Positives = 40/82 (48%), Gaps = 6/82 (7%)
Query: 705 RVLVYSCRHGYELQGREQLTC-TQEGW--DFQPPLCKDVNECADGAHPPCHASARCRNTK 761
R+L + C HG + C Q G+ D C D++EC+ P + C+NTK
Sbjct: 2368 RMLAHLCAHGECINSLGSFRCHCQAGYTPDATATTCLDMDECSQVPKP---CTFLCKNTK 2424
Query: 762 GGFQCLCADPYELGDDGRTCVD 783
G F C C Y L +DGRTC D
Sbjct: 2425 GSFLCSCPRGYLLEEDGRTCKD 2446
Score = 48.5 bits (114), Expect = 3e-05
Identities = 30/77 (38%), Positives = 37/77 (48%), Gaps = 7/77 (9%)
Query: 711 CRHG--YELQGREQLTCTQEGWDFQPP--LCKDVNECADGAHPPCHASARCRNTKGGFQC 766
C HG + G C G+ P C DV+EC CH RC NT+G FQC
Sbjct: 458 CHHGDCVNIPGTYHCRC-YPGFQATPTRQACVDVDECIVSGGL-CHLG-RCVNTEGSFQC 514
Query: 767 LCADPYELGDDGRTCVD 783
+C +EL DG+ CVD
Sbjct: 515 VCNAGFELSPDGKNCVD 531
Score = 47.4 bits (111), Expect = 6e-05
Identities = 29/77 (37%), Positives = 39/77 (50%), Gaps = 4/77 (5%)
Query: 699 CEESGRRVLVYSCRHGYELQ-GREQLTCTQEGWDF-QPPLCKDVNECADGAHPPCHASAR 756
CE+ + C+HG + Q G + +C Q Q C D NECA PP SA
Sbjct: 2526 CEDVNECDGPHRCQHGCQNQLGGYRCSCPQGFTQHSQWAQCVDENECA--LSPPTCGSAS 2583
Query: 757 CRNTKGGFQCLCADPYE 773
CRNT GGF+C+C ++
Sbjct: 2584 CRNTLGGFRCVCPSGFD 2600
Score = 46.2 bits (108), Expect = 1e-04
Identities = 21/48 (43%), Positives = 25/48 (52%), Gaps = 1/48 (2%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 784
C D +EC C C NT G F CLC D +EL DG+ CVD+
Sbjct: 1884 CVDFDECTTLVGQVCRFG-HCLNTAGSFHCLCQDGFELTADGKNCVDT 1930
Score = 45.8 bits (107), Expect = 2e-04
Identities = 26/73 (35%), Positives = 35/73 (47%), Gaps = 5/73 (6%)
Query: 713 HGYELQGREQLTCTQEGWDFQPP--LCKDVNECADGAHPPCHASARCRNTKGGFQCLCAD 770
H +G + +C Q G+ P C DV+EC + +P C N GG +CLC D
Sbjct: 1169 HCINTEGSYRCSCGQ-GYSLMPDGRACADVDECEE--NPRVCDQGHCTNMPGGHRCLCYD 1225
Query: 771 PYELGDDGRTCVD 783
+ D RTCVD
Sbjct: 1226 GFMATPDMRTCVD 1238
Score = 45.8 bits (107), Expect = 2e-04
Identities = 37/135 (27%), Positives = 56/135 (41%), Gaps = 18/135 (13%)
Query: 660 DFESCDSITG--------MNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSC 711
DF+ C ++ G +N QD GF + + + V E L +C
Sbjct: 1886 DFDECTTLVGQVCRFGHCLNTAGSFHCLCQD---GFELTADGKNCVDTNEC--LSLAGTC 1940
Query: 712 RHG--YELQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCA 769
G L+G + C G+ Q C D++EC++ P C N+ G FQCLC
Sbjct: 1941 LPGTCQNLEGSFRCICPP-GFQVQSDHCIDIDECSE--EPNLCLFGTCTNSPGSFQCLCP 1997
Query: 770 DPYELGDDGRTCVDS 784
+ L D+G C D+
Sbjct: 1998 PGFVLSDNGHRCFDT 2012
Score = 44.7 bits (104), Expect = 4e-04
Identities = 19/48 (39%), Positives = 26/48 (54%), Gaps = 3/48 (6%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 784
C D++EC P + C NT+G F+C C +G DGR CVD+
Sbjct: 570 CMDIDECQT---PGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVCVDT 614
Score = 43.1 bits (100), Expect = 0.001
Identities = 21/47 (44%), Positives = 25/47 (53%), Gaps = 2/47 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C DVNEC + P + RC NT G F+C C + L GR CVD
Sbjct: 867 CDDVNECE--SFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVD 911
Score = 42.7 bits (99), Expect = 0.001
Identities = 21/55 (38%), Positives = 30/55 (54%), Gaps = 6/55 (10%)
Query: 732 FQPPL---CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
F+P L C+D++EC+ P + RC NT+G + C C Y L +DG C D
Sbjct: 2156 FEPGLMMTCEDIDECSLN---PLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCRD 2207
Score = 42.4 bits (98), Expect = 0.002
Identities = 18/46 (39%), Positives = 26/46 (56%), Gaps = 2/46 (4%)
Query: 738 KDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
+D+NECA P A+ C N +G ++C+C YE G G+ C D
Sbjct: 681 RDINECA--LDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTD 724
Score = 42.4 bits (98), Expect = 0.002
Identities = 21/49 (42%), Positives = 22/49 (44%), Gaps = 2/49 (4%)
Query: 735 PLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
P KDVNEC P CRNT G F C CA + L R C D
Sbjct: 982 PFYKDVNECK--VFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTD 1028
Score = 42.4 bits (98), Expect = 0.002
Identities = 20/48 (41%), Positives = 25/48 (52%), Gaps = 3/48 (6%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 784
C D+NECAD P + C NT G + C C +EL G CVD+
Sbjct: 1443 CTDINECAD---PVNCINGVCINTPGSYLCSCPQDFELNPSGVGCVDT 1487
Score = 42.0 bits (97), Expect = 0.002
Identities = 27/79 (34%), Positives = 35/79 (44%), Gaps = 12/79 (15%)
Query: 711 CRHGY--ELQGREQLTCTQEGWDFQPPL--CKDVNECA--DGAHPPCHASARCRNTKGGF 764
C HG + G Q +C G+ P C D+NEC +G C NT+G +
Sbjct: 1124 CPHGQCVNVIGAFQCSC-HAGFQSTPDRQGCVDINECRVQNGG-----CDVHCINTEGSY 1177
Query: 765 QCLCADPYELGDDGRTCVD 783
+C C Y L DGR C D
Sbjct: 1178 RCSCGQGYSLMPDGRACAD 1196
Score = 41.6 bits (96), Expect = 0.003
Identities = 42/153 (27%), Positives = 60/153 (39%), Gaps = 27/153 (17%)
Query: 640 DNTGLTRVPMDAFQVGKFPEDFESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHC 699
D TG+ V D VG P +C ++ G +C + E G + C
Sbjct: 2118 DFTGINCVDTDECSVGH-PCGQGTCTNVIG------------GFECACADGFEPGLMMTC 2164
Query: 700 EESGRRVL-----VYSCRHGYELQGREQLTCTQEGWDFQPP--LCKDVNECADGAHPPCH 752
E+ L + C + +G TC G+ + +C+DV+ECADG CH
Sbjct: 2165 EDIDECSLNPLLCAFRC---HNTEGSYLCTCPA-GYTLREDGAMCRDVDECADG-QQDCH 2219
Query: 753 A-SARCRNTKGGFQCLCADPYE-LGDDGRTCVD 783
A C+N G F C+C L G C D
Sbjct: 2220 ARGMECKNLIGTFACVCPPGMRPLPGSGEGCTD 2252
Score = 41.2 bits (95), Expect = 0.004
Identities = 20/47 (42%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C+DV+ECA G A C N G F+C+C YEL G C D
Sbjct: 1402 CQDVDECAQGN---LCAFGSCENLPGMFRCICNGGYELDRGGGNCTD 1445
Score = 40.8 bits (94), Expect = 0.006
Identities = 24/68 (35%), Positives = 31/68 (45%), Gaps = 2/68 (2%)
Query: 738 KDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRVTWISMSL 797
+DVNECA+ +P + C NT G F+C C Y L G CVD+
Sbjct: 2083 EDVNECAE--NPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGHPCGQGT 2140
Query: 798 AALLIGGF 805
+IGGF
Sbjct: 2141 CTNVIGGF 2148
Score = 40.4 bits (93), Expect = 0.007
Identities = 20/49 (40%), Positives = 24/49 (48%), Gaps = 4/49 (8%)
Query: 736 LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 784
+CKDV+EC PC S CRN G + C C L G C+DS
Sbjct: 763 ICKDVDECLSS---PC-VSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDS 807
Score = 39.7 bits (91), Expect = 0.012
Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 7/100 (7%)
Query: 686 GFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCT-QEGWDFQPPL--CKDVNE 742
GF + G + +E G + C +G + C G+++ L C+DV+E
Sbjct: 1709 GFLTDIHTGKPLDIDECGEIPAI--CANGICINQIGSFRCECPAGFNYNSILLACEDVDE 1766
Query: 743 CADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCV 782
C PC +A C N G ++C C Y+L G CV
Sbjct: 1767 CGS-RESPCQQNADCINIPGSYRCKCTRGYKLSPGG-ACV 1804
Score = 39.7 bits (91), Expect = 0.012
Identities = 20/48 (41%), Positives = 24/48 (50%), Gaps = 3/48 (6%)
Query: 737 CKDVNECADGAHP-PCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C D +EC+ A P PC A C NT G F+C C + L G C D
Sbjct: 2483 CFDNDECS--AQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCED 2528
Score = 39.7 bits (91), Expect = 0.012
Identities = 25/56 (44%), Positives = 29/56 (51%), Gaps = 6/56 (10%)
Query: 729 GWDFQPPL--CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCV 782
G+DF L C++V+ECA G PC S C NT GGF C C Y G CV
Sbjct: 2598 GFDFDQALGGCQEVDECA-GRRGPCSYS--CANTPGGFLCGCPQGYFRAGQGH-CV 2649
Score = 38.5 bits (88), Expect = 0.028
Identities = 19/47 (40%), Positives = 24/47 (51%), Gaps = 4/47 (8%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C+DVNEC DG H H C+N GG++C C + CVD
Sbjct: 2526 CEDVNEC-DGPHRCQHG---CQNQLGGYRCSCPQGFTQHSQWAQCVD 2568
Score = 38.1 bits (87), Expect = 0.036
Identities = 30/98 (30%), Positives = 39/98 (39%), Gaps = 8/98 (8%)
Query: 688 PESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPL--CKDVNECAD 745
P+ D CEE+ R V H + G + C +G+ P + C DV+EC
Sbjct: 1189 PDGRACADVDECEENPR---VCDQGHCTNMPGGHRCLC-YDGFMATPDMRTCVDVDECDL 1244
Query: 746 GAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
H H C NTKG F C C Y + C D
Sbjct: 1245 NPHICLHGD--CENTKGSFVCHCQLGYMVRKGATGCSD 1280
Score = 37.4 bits (85), Expect = 0.061
Identities = 33/133 (24%), Positives = 49/133 (36%), Gaps = 27/133 (20%)
Query: 653 QVGKFPEDFESCDSITGMNLEAWRETFPQDDKCGFPESV--ENGDFVHCEESGRRVLVYS 710
Q+G F C+ G N + D+CG ES +N D ++ S R
Sbjct: 1740 QIGSF-----RCECPAGFNYNSILLACEDVDECGSRESPCQQNADCINIPGSYR----CK 1790
Query: 711 CRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCAD 770
C GY+L C NEC + + H C +T+G + CLC
Sbjct: 1791 CTRGYKLS--------------PGGACVGRNECREIPNVCSHGD--CMDTEGSYMCLCHR 1834
Query: 771 PYELGDDGRTCVD 783
++ D C+D
Sbjct: 1835 GFQASADQTLCMD 1847
Score = 37.0 bits (84), Expect = 0.080
Identities = 18/47 (38%), Positives = 22/47 (46%), Gaps = 2/47 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C DV+ECA P C NT G ++C C +EL G C D
Sbjct: 1069 CMDVDECA--RDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTACED 1113
Score = 36.6 bits (83), Expect = 0.10
Identities = 21/47 (44%), Positives = 24/47 (51%), Gaps = 3/47 (6%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C DV+EC G H C + A C N G F C C P +G DG C D
Sbjct: 1278 CSDVDECEVGGHN-CDSHASCLNIPGSFSCRCL-PGWVG-DGFECHD 1321
Score = 36.6 bits (83), Expect = 0.10
Identities = 23/67 (34%), Positives = 29/67 (43%), Gaps = 6/67 (8%)
Query: 721 EQLTCTQEGWDFQPP----LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGD 776
E T G FQP + +D++EC + P C NT G FQC C Y L +
Sbjct: 1541 EYRTLCPGGEGFQPNRITVILEDIDECQE--LPGLCQGGDCVNTFGSFQCECPPGYHLSE 1598
Query: 777 DGRTCVD 783
R C D
Sbjct: 1599 HTRICED 1605
Score = 36.6 bits (83), Expect = 0.10
Identities = 15/48 (31%), Positives = 24/48 (50%), Gaps = 2/48 (4%)
Query: 736 LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
+C+D++EC+ H C NT G + C+C Y + G C+D
Sbjct: 1602 ICEDIDECS--THSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMD 1647
Score = 36.2 bits (82), Expect = 0.14
Identities = 21/65 (32%), Positives = 33/65 (50%), Gaps = 3/65 (4%)
Query: 719 GREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDG 778
G + TC Q G+ C+D +ECA+ C + +C N GG++C C ++ +D
Sbjct: 1343 GSYRCTCRQ-GFAGDGFFCEDRDECAENVDL-CD-NGQCLNAPGGYRCECEMGFDPTEDH 1399
Query: 779 RTCVD 783
R C D
Sbjct: 1400 RACQD 1404
Score = 35.0 bits (79), Expect = 0.30
Identities = 23/68 (33%), Positives = 29/68 (42%), Gaps = 6/68 (8%)
Query: 718 QGREQLTCTQEGWDFQPP--LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELG 775
+G Q C G++ P C D NECA C + C N G F CLC + L
Sbjct: 509 EGSFQCVCNA-GFELSPDGKNCVDHNECATSTM--C-VNGVCLNEDGSFSCLCKPGFLLA 564
Query: 776 DDGRTCVD 783
G C+D
Sbjct: 565 PGGHYCMD 572
Score = 35.0 bits (79), Expect = 0.30
Identities = 21/78 (26%), Positives = 31/78 (39%), Gaps = 2/78 (2%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRVTWISMS 796
C D NEC A P + RC NT G F+C C + ++ C D + P + +
Sbjct: 2250 CTDDNECH--AQPDLCVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQT 2307
Query: 797 LAALLIGGFAGLTSTVIC 814
+ L +T C
Sbjct: 2308 MCRSLSSSSEAVTRAECC 2325
Score = 33.9 bits (76), Expect = 0.68
Identities = 17/47 (36%), Positives = 20/47 (42%), Gaps = 2/47 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C+DV+EC A P C N G F C C + L D C D
Sbjct: 245 CQDVDECQ--AVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
Score = 33.9 bits (76), Expect = 0.68
Identities = 17/45 (37%), Positives = 20/45 (44%), Gaps = 2/45 (4%)
Query: 731 DFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELG 775
D Q C D++EC P C NT G F+C C YE G
Sbjct: 1020 DAQERNCTDIDECR--ISPDLCGQGTCVNTPGSFECECFPGYESG 1062
Score = 33.1 bits (74), Expect = 1.2
Identities = 18/53 (33%), Positives = 24/53 (45%), Gaps = 2/53 (3%)
Query: 738 KDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRV 790
+DV+EC AH H C N+ G F+C C Y TC+D +V
Sbjct: 2362 RDVDECRMLAHLCAHGE--CINSLGSFRCHCQAGYTPDATATTCLDMDECSQV 2412
Score = 32.3 bits (72), Expect = 2.0
Identities = 17/55 (30%), Positives = 22/55 (40%), Gaps = 3/55 (5%)
Query: 729 GWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
GW C D++EC H C C N G ++C C + DG C D
Sbjct: 1311 GWVGDGFECHDLDECVSQEHR-CSPRGDCLNVPGSYRCTCRQGF--AGDGFFCED 1362
Score = 30.0 bits (66), Expect = 9.8
Identities = 14/47 (29%), Positives = 21/47 (44%), Gaps = 2/47 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C DV+ECA + + C+N+ G + C C + D C D
Sbjct: 722 CTDVDECA--LNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKD 766
Score = 30.0 bits (66), Expect = 9.8
Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 3/32 (9%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLC 768
CKD++EC H + C NT G F C C
Sbjct: 2444 CKDLDECTSRQH---NCQFLCVNTVGAFTCRC 2472
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 52.4 bits (124), Expect = 2e-06
Identities = 32/94 (34%), Positives = 43/94 (45%), Gaps = 16/94 (17%)
Query: 688 PESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGA 747
P + NG +H + R + C GY+L + C+DV+ECA G
Sbjct: 247 PCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKA-------------CEDVDECAAGL 293
Query: 748 HPPCHASARCRNTKGGFQCLCADPYELGDDGRTC 781
H C NT+G F+C+C YELG DGR C
Sbjct: 294 AQCAHG---CLNTQGSFKCVCHAGYELGADGRQC 324
Score = 42.4 bits (98), Expect = 0.002
Identities = 26/75 (34%), Positives = 31/75 (41%), Gaps = 6/75 (8%)
Query: 711 CRHGYELQGREQLTCTQEGW--DFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLC 768
C HG L G+ D C DV++CAD PC C N GG++C C
Sbjct: 342 CSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADS---PCCQQV-CTNNPGGYECGC 397
Query: 769 ADPYELGDDGRTCVD 783
Y L DG C D
Sbjct: 398 YAGYRLSADGCGCED 412
Score = 39.3 bits (90), Expect = 0.016
Identities = 32/120 (26%), Positives = 39/120 (32%), Gaps = 37/120 (30%)
Query: 699 CEESGRRVLVY-SCRHGYELQGREQLTCTQEGWDFQPP------------LCKDVNECAD 745
C RR + Y R Y + R L C + GW QP LC C
Sbjct: 83 CVGHERRTVYYMGYRQVYTTEARTVLRCCR-GWMQQPDEEGCLSAECSASLCFHGGRCVP 141
Query: 746 GAHPPCHASA-----------------------RCRNTKGGFQCLCADPYELGDDGRTCV 782
G+ PCH RC NT G + C C + L D RTC+
Sbjct: 142 GSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCL 201
Score = 38.5 bits (88), Expect = 0.028
Identities = 19/45 (42%), Positives = 22/45 (48%), Gaps = 3/45 (6%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTC 781
C+DV+ECA H C N G FQC C Y L +D R C
Sbjct: 410 CEDVDECASSRGGCEH---HCTNLAGSFQCSCEAGYRLHEDRRGC 451
Score = 34.3 bits (77), Expect = 0.52
Identities = 24/73 (32%), Positives = 29/73 (39%), Gaps = 11/73 (15%)
Query: 711 CRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCAD 770
C GYEL G + C + + VN C H C +T G C C
Sbjct: 311 CHAGYEL-GADGRQCYRIEMEI-------VNSCEANNGGCSHG---CSHTSAGPLCTCPR 359
Query: 771 PYELGDDGRTCVD 783
YEL D RTC+D
Sbjct: 360 GYELDTDQRTCID 372
>gi|157384998 low density lipoprotein receptor-related protein 4
[Homo sapiens]
Length = 1905
Score = 51.2 bits (121), Expect = 4e-06
Identities = 44/160 (27%), Positives = 67/160 (41%), Gaps = 33/160 (20%)
Query: 639 CDNTGLTRVPMDAFQV--GKFPEDFESCDSITGMNLEAWRETFPQ--------DDKCGFP 688
C+NTG + +D F G+ + C+ + + + PQ ++ C
Sbjct: 304 CENTGSPQCALDQFLCWNGRCIGQRKLCNGVNDCGDNS--DESPQQNCRPRTGEENC--- 358
Query: 689 ESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNECADGAH 748
+V NG + R + +C GY L T++G C+DVNECA+ +
Sbjct: 359 -NVNNGGCAQKCQMVRGAVQCTCHTGYRL--------TEDGHT-----CQDVNECAEEGY 404
Query: 749 PPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLP 788
S C N++G FQC C YEL D R+C G P
Sbjct: 405 ----CSQGCTNSEGAFQCWCETGYELRPDRRSCKALGPEP 440
>gi|122937283 6720455I24Rik homolog [Homo sapiens]
Length = 1413
Score = 51.2 bits (121), Expect = 4e-06
Identities = 27/90 (30%), Positives = 41/90 (45%), Gaps = 4/90 (4%)
Query: 685 CGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQL-TCTQEGWDFQPPLCKDVNEC 743
CG PE V++ V +Y+C GY L ++ C G +PP C +++EC
Sbjct: 698 CGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDEC 757
Query: 744 ADGAHPPCHASARCRNTKGGFQCLCADPYE 773
PC C++ G+ CLC+ YE
Sbjct: 758 RS---QPCLHGGSCQDRVAGYLCLCSTGYE 784
Score = 35.0 bits (79), Expect = 0.30
Identities = 31/108 (28%), Positives = 45/108 (41%), Gaps = 28/108 (25%)
Query: 699 CEESGRRVLVYSCRHGYELQ---GREQLTCTQEGWDFQPPLCK-DVNECADGAHPPCHAS 754
CE + C+HG + Q G C Q G + C+ DV++C+ PC
Sbjct: 346 CETAQSPCDTKECQHGGQCQVENGSAVCVC-QAG--YTGAACEMDVDDCSPD---PCLNG 399
Query: 755 ARCRNTKGGFQCLCADPY-----ELGD-------------DGRTCVDS 784
C + G + CLCA+P+ E GD +G TCVD+
Sbjct: 400 GSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDA 447
>gi|110347437 latent transforming growth factor beta binding protein
4 isoform c [Homo sapiens]
Length = 1557
Score = 50.8 bits (120), Expect = 5e-06
Identities = 38/126 (30%), Positives = 48/126 (38%), Gaps = 18/126 (14%)
Query: 658 PEDFESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYEL 717
P F+ +G +L R T + G P +G + E S R SC GY
Sbjct: 746 PGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFR----CSCAPGYRA 801
Query: 718 QGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDD 777
+P C DVNEC +G C C NT G F C CA Y G
Sbjct: 802 PSG------------RPGPCADVNECLEGDF--CFPHGECLNTDGSFACTCAPGYRPGPR 847
Query: 778 GRTCVD 783
G +C+D
Sbjct: 848 GASCLD 853
Score = 50.8 bits (120), Expect = 5e-06
Identities = 24/47 (51%), Positives = 29/47 (61%), Gaps = 2/47 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C+DV+EC + + C A A C+N G FQCLC YE DGR CVD
Sbjct: 980 CQDVDECRNRSF--CGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVD 1024
Score = 46.6 bits (109), Expect = 1e-04
Identities = 36/115 (31%), Positives = 49/115 (42%), Gaps = 26/115 (22%)
Query: 658 PEDFESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCR--HGY 715
PE+ S G E + E + ++CG + NG V E ++CR GY
Sbjct: 1445 PEEPPEGGSYAGSLAEPYEEL--EAEECGILDGCTNGRCVRVPEG------FTCRCFDGY 1496
Query: 716 ELQGREQLTCTQEGWDFQPPLCKDVNEC--ADGAHPPCHASARCRNTKGGFQCLC 768
L D C D+NEC A+ A P C +ARC NT G F+C+C
Sbjct: 1497 RL-------------DMTRMACVDINECDEAEAASPLC-VNARCLNTDGSFRCIC 1537
Score = 45.1 bits (105), Expect = 3e-04
Identities = 21/47 (44%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C+DV+ECA PPC RC NT+G FQC+C ++ G C D
Sbjct: 683 CQDVDECARSP-PPC-TYGRCENTEGSFQCVCPMGFQPNTAGSECED 727
Score = 42.7 bits (99), Expect = 0.001
Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 8/91 (8%)
Query: 697 VHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-----WDFQPPLCKDVNECADGAHPPC 751
V C +G V+ C+ E G + +G ++ C+DV+ECA G C
Sbjct: 243 VCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGR--C 300
Query: 752 HASARCRNTKGGFQCLCADPYELGDDGRTCV 782
C NT+GG+ C+C D + L +C+
Sbjct: 301 Q-HGECANTRGGYTCVCPDGFLLDSSRSSCI 330
Score = 42.7 bits (99), Expect = 0.001
Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 2/54 (3%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRV 790
C DV+EC PPC A RC N+ G F+C+C + G C+D RV
Sbjct: 518 CIDVDECRR-VPPPC-APGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRV 569
Score = 42.0 bits (97), Expect = 0.002
Identities = 20/47 (42%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C DV+EC PPC RC NT G F C+C Y+ G +C D
Sbjct: 560 CLDVDEC-HRVPPPCDLG-RCENTPGSFLCVCPAGYQAAPHGASCQD 604
Score = 39.3 bits (90), Expect = 0.016
Identities = 20/48 (41%), Positives = 23/48 (47%), Gaps = 2/48 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 784
C D +ECAD P C RC NT G + C C P L R CV +
Sbjct: 1227 CIDNDECAD-EEPACEGG-RCVNTVGSYHCTCEPPLVLDGSQRRCVSN 1272
Score = 38.5 bits (88), Expect = 0.028
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C DV+EC++ C S C NT G F+C+C + G D +C+D
Sbjct: 851 CLDVDECSE--EDLCQ-SGICTNTDGSFECICPPGHRAGPDLASCLD 894
Score = 37.4 bits (85), Expect = 0.061
Identities = 19/46 (41%), Positives = 22/46 (47%), Gaps = 2/46 (4%)
Query: 738 KDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
+DV+ECA PPC RC NT G F C C + G C D
Sbjct: 642 EDVDECAQEP-PPC-GPGRCDNTAGSFHCACPAGFRSRGPGAPCQD 685
Score = 35.4 bits (80), Expect = 0.23
Identities = 19/49 (38%), Positives = 26/49 (53%), Gaps = 4/49 (8%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCL--CADPYELGDDGRTCVD 783
C DV+EC + C S RC N+ G ++C+ C Y G +G TC D
Sbjct: 892 CLDVDECRERGPALC-GSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDD 938
Score = 32.3 bits (72), Expect = 2.0
Identities = 19/48 (39%), Positives = 23/48 (47%), Gaps = 2/48 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCA-DPYELGDDGRTCVD 783
C DV+EC + C A RC NT G ++C A DP G C D
Sbjct: 936 CDDVDECQEYGPEICGAQ-RCENTPGSYRCTPACDPGYQPTPGGGCQD 982
Score = 30.8 bits (68), Expect = 5.7
Identities = 12/32 (37%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLC 768
C+DV+EC P C+N G F+C+C
Sbjct: 602 CQDVDECTQS--PGLCGRGACKNLPGSFRCVC 631
Score = 30.4 bits (67), Expect = 7.5
Identities = 16/37 (43%), Positives = 20/37 (54%), Gaps = 2/37 (5%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYE 773
C DVNEC + C A A C N +G F C+C + E
Sbjct: 1022 CVDVNEC-ETLQGVCGA-ALCENVEGSFLCVCPNSPE 1056
Score = 30.4 bits (67), Expect = 7.5
Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 1/49 (2%)
Query: 736 LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 784
L +DV+EC C + C NT G+ C C++ Y C+D+
Sbjct: 1183 LRRDVDECQLFRDQVCKSGV-CVNTAPGYSCYCSNGYYYHTQRLECIDN 1230
>gi|110347412 latent transforming growth factor beta binding protein
4 isoform b [Homo sapiens]
Length = 1587
Score = 50.8 bits (120), Expect = 5e-06
Identities = 38/126 (30%), Positives = 48/126 (38%), Gaps = 18/126 (14%)
Query: 658 PEDFESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYEL 717
P F+ +G +L R T + G P +G + E S R SC GY
Sbjct: 776 PGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFR----CSCAPGYRA 831
Query: 718 QGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDD 777
+P C DVNEC +G C C NT G F C CA Y G
Sbjct: 832 PSG------------RPGPCADVNECLEGDF--CFPHGECLNTDGSFACTCAPGYRPGPR 877
Query: 778 GRTCVD 783
G +C+D
Sbjct: 878 GASCLD 883
Score = 50.8 bits (120), Expect = 5e-06
Identities = 24/47 (51%), Positives = 29/47 (61%), Gaps = 2/47 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C+DV+EC + + C A A C+N G FQCLC YE DGR CVD
Sbjct: 1010 CQDVDECRNRSF--CGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVD 1054
Score = 46.6 bits (109), Expect = 1e-04
Identities = 36/115 (31%), Positives = 49/115 (42%), Gaps = 26/115 (22%)
Query: 658 PEDFESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCR--HGY 715
PE+ S G E + E + ++CG + NG V E ++CR GY
Sbjct: 1475 PEEPPEGGSYAGSLAEPYEEL--EAEECGILDGCTNGRCVRVPEG------FTCRCFDGY 1526
Query: 716 ELQGREQLTCTQEGWDFQPPLCKDVNEC--ADGAHPPCHASARCRNTKGGFQCLC 768
L D C D+NEC A+ A P C +ARC NT G F+C+C
Sbjct: 1527 RL-------------DMTRMACVDINECDEAEAASPLC-VNARCLNTDGSFRCIC 1567
Score = 45.1 bits (105), Expect = 3e-04
Identities = 21/47 (44%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C+DV+ECA PPC RC NT+G FQC+C ++ G C D
Sbjct: 713 CQDVDECARSP-PPC-TYGRCENTEGSFQCVCPMGFQPNTAGSECED 757
Score = 42.7 bits (99), Expect = 0.001
Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 8/91 (8%)
Query: 697 VHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-----WDFQPPLCKDVNECADGAHPPC 751
V C +G V+ C+ E G + +G ++ C+DV+ECA G C
Sbjct: 273 VCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGR--C 330
Query: 752 HASARCRNTKGGFQCLCADPYELGDDGRTCV 782
C NT+GG+ C+C D + L +C+
Sbjct: 331 Q-HGECANTRGGYTCVCPDGFLLDSSRSSCI 360
Score = 42.7 bits (99), Expect = 0.001
Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 2/54 (3%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRV 790
C DV+EC PPC A RC N+ G F+C+C + G C+D RV
Sbjct: 548 CIDVDECRR-VPPPC-APGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRV 599
Score = 42.0 bits (97), Expect = 0.002
Identities = 20/47 (42%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C DV+EC PPC RC NT G F C+C Y+ G +C D
Sbjct: 590 CLDVDEC-HRVPPPCDLG-RCENTPGSFLCVCPAGYQAAPHGASCQD 634
Score = 39.3 bits (90), Expect = 0.016
Identities = 20/48 (41%), Positives = 23/48 (47%), Gaps = 2/48 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 784
C D +ECAD P C RC NT G + C C P L R CV +
Sbjct: 1257 CIDNDECAD-EEPACEGG-RCVNTVGSYHCTCEPPLVLDGSQRRCVSN 1302
Score = 38.5 bits (88), Expect = 0.028
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C DV+EC++ C S C NT G F+C+C + G D +C+D
Sbjct: 881 CLDVDECSE--EDLCQ-SGICTNTDGSFECICPPGHRAGPDLASCLD 924
Score = 37.4 bits (85), Expect = 0.061
Identities = 19/46 (41%), Positives = 22/46 (47%), Gaps = 2/46 (4%)
Query: 738 KDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
+DV+ECA PPC RC NT G F C C + G C D
Sbjct: 672 EDVDECAQEP-PPC-GPGRCDNTAGSFHCACPAGFRSRGPGAPCQD 715
Score = 35.4 bits (80), Expect = 0.23
Identities = 19/49 (38%), Positives = 26/49 (53%), Gaps = 4/49 (8%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCL--CADPYELGDDGRTCVD 783
C DV+EC + C S RC N+ G ++C+ C Y G +G TC D
Sbjct: 922 CLDVDECRERGPALC-GSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDD 968
Score = 32.3 bits (72), Expect = 2.0
Identities = 19/48 (39%), Positives = 23/48 (47%), Gaps = 2/48 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCA-DPYELGDDGRTCVD 783
C DV+EC + C A RC NT G ++C A DP G C D
Sbjct: 966 CDDVDECQEYGPEICGAQ-RCENTPGSYRCTPACDPGYQPTPGGGCQD 1012
Score = 30.8 bits (68), Expect = 5.7
Identities = 12/32 (37%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLC 768
C+DV+EC P C+N G F+C+C
Sbjct: 632 CQDVDECTQS--PGLCGRGACKNLPGSFRCVC 661
Score = 30.4 bits (67), Expect = 7.5
Identities = 16/37 (43%), Positives = 20/37 (54%), Gaps = 2/37 (5%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYE 773
C DVNEC + C A A C N +G F C+C + E
Sbjct: 1052 CVDVNEC-ETLQGVCGA-ALCENVEGSFLCVCPNSPE 1086
Score = 30.4 bits (67), Expect = 7.5
Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 1/49 (2%)
Query: 736 LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 784
L +DV+EC C + C NT G+ C C++ Y C+D+
Sbjct: 1213 LRRDVDECQLFRDQVCKSGV-CVNTAPGYSCYCSNGYYYHTQRLECIDN 1260
>gi|110347431 latent transforming growth factor beta binding protein
4 isoform a [Homo sapiens]
Length = 1624
Score = 50.8 bits (120), Expect = 5e-06
Identities = 38/126 (30%), Positives = 48/126 (38%), Gaps = 18/126 (14%)
Query: 658 PEDFESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYEL 717
P F+ +G +L R T + G P +G + E S R SC GY
Sbjct: 813 PGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFR----CSCAPGYRA 868
Query: 718 QGREQLTCTQEGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDD 777
+P C DVNEC +G C C NT G F C CA Y G
Sbjct: 869 PSG------------RPGPCADVNECLEGDF--CFPHGECLNTDGSFACTCAPGYRPGPR 914
Query: 778 GRTCVD 783
G +C+D
Sbjct: 915 GASCLD 920
Score = 50.8 bits (120), Expect = 5e-06
Identities = 24/47 (51%), Positives = 29/47 (61%), Gaps = 2/47 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C+DV+EC + + C A A C+N G FQCLC YE DGR CVD
Sbjct: 1047 CQDVDECRNRSF--CGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVD 1091
Score = 46.6 bits (109), Expect = 1e-04
Identities = 36/115 (31%), Positives = 49/115 (42%), Gaps = 26/115 (22%)
Query: 658 PEDFESCDSITGMNLEAWRETFPQDDKCGFPESVENGDFVHCEESGRRVLVYSCR--HGY 715
PE+ S G E + E + ++CG + NG V E ++CR GY
Sbjct: 1512 PEEPPEGGSYAGSLAEPYEEL--EAEECGILDGCTNGRCVRVPEG------FTCRCFDGY 1563
Query: 716 ELQGREQLTCTQEGWDFQPPLCKDVNEC--ADGAHPPCHASARCRNTKGGFQCLC 768
L D C D+NEC A+ A P C +ARC NT G F+C+C
Sbjct: 1564 RL-------------DMTRMACVDINECDEAEAASPLC-VNARCLNTDGSFRCIC 1604
Score = 45.1 bits (105), Expect = 3e-04
Identities = 21/47 (44%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C+DV+ECA PPC RC NT+G FQC+C ++ G C D
Sbjct: 750 CQDVDECARSP-PPC-TYGRCENTEGSFQCVCPMGFQPNTAGSECED 794
Score = 42.7 bits (99), Expect = 0.001
Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 8/91 (8%)
Query: 697 VHCEESGRRVLVYSCRHGYELQGREQLTCTQEG-----WDFQPPLCKDVNECADGAHPPC 751
V C +G V+ C+ E G + +G ++ C+DV+ECA G C
Sbjct: 310 VCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGR--C 367
Query: 752 HASARCRNTKGGFQCLCADPYELGDDGRTCV 782
C NT+GG+ C+C D + L +C+
Sbjct: 368 Q-HGECANTRGGYTCVCPDGFLLDSSRSSCI 397
Score = 42.7 bits (99), Expect = 0.001
Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 2/54 (3%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDSGRLPRV 790
C DV+EC PPC A RC N+ G F+C+C + G C+D RV
Sbjct: 585 CIDVDECRR-VPPPC-APGRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRV 636
Score = 42.0 bits (97), Expect = 0.002
Identities = 20/47 (42%), Positives = 24/47 (51%), Gaps = 2/47 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C DV+EC PPC RC NT G F C+C Y+ G +C D
Sbjct: 627 CLDVDEC-HRVPPPCDLG-RCENTPGSFLCVCPAGYQAAPHGASCQD 671
Score = 39.3 bits (90), Expect = 0.016
Identities = 20/48 (41%), Positives = 23/48 (47%), Gaps = 2/48 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 784
C D +ECAD P C RC NT G + C C P L R CV +
Sbjct: 1294 CIDNDECAD-EEPACEGG-RCVNTVGSYHCTCEPPLVLDGSQRRCVSN 1339
Score = 38.5 bits (88), Expect = 0.028
Identities = 18/47 (38%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C DV+EC++ C S C NT G F+C+C + G D +C+D
Sbjct: 918 CLDVDECSE--EDLCQ-SGICTNTDGSFECICPPGHRAGPDLASCLD 961
Score = 37.4 bits (85), Expect = 0.061
Identities = 19/46 (41%), Positives = 22/46 (47%), Gaps = 2/46 (4%)
Query: 738 KDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
+DV+ECA PPC RC NT G F C C + G C D
Sbjct: 709 EDVDECAQEP-PPC-GPGRCDNTAGSFHCACPAGFRSRGPGAPCQD 752
Score = 35.4 bits (80), Expect = 0.23
Identities = 19/49 (38%), Positives = 26/49 (53%), Gaps = 4/49 (8%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCL--CADPYELGDDGRTCVD 783
C DV+EC + C S RC N+ G ++C+ C Y G +G TC D
Sbjct: 959 CLDVDECRERGPALC-GSQRCENSPGSYRCVRDCDPGYHAGPEG-TCDD 1005
Score = 32.3 bits (72), Expect = 2.0
Identities = 19/48 (39%), Positives = 23/48 (47%), Gaps = 2/48 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCA-DPYELGDDGRTCVD 783
C DV+EC + C A RC NT G ++C A DP G C D
Sbjct: 1003 CDDVDECQEYGPEICGAQ-RCENTPGSYRCTPACDPGYQPTPGGGCQD 1049
Score = 30.8 bits (68), Expect = 5.7
Identities = 12/32 (37%), Positives = 17/32 (53%), Gaps = 2/32 (6%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLC 768
C+DV+EC P C+N G F+C+C
Sbjct: 669 CQDVDECTQS--PGLCGRGACKNLPGSFRCVC 698
Score = 30.4 bits (67), Expect = 7.5
Identities = 16/37 (43%), Positives = 20/37 (54%), Gaps = 2/37 (5%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYE 773
C DVNEC + C A A C N +G F C+C + E
Sbjct: 1089 CVDVNEC-ETLQGVCGA-ALCENVEGSFLCVCPNSPE 1123
Score = 30.4 bits (67), Expect = 7.5
Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 1/49 (2%)
Query: 736 LCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVDS 784
L +DV+EC C + C NT G+ C C++ Y C+D+
Sbjct: 1250 LRRDVDECQLFRDQVCKSGV-CVNTAPGYSCYCSNGYYYHTQRLECIDN 1297
>gi|46249414 latent transforming growth factor beta binding protein 1
isoform LTBP-1L [Homo sapiens]
Length = 1722
Score = 50.4 bits (119), Expect = 7e-06
Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 7/90 (7%)
Query: 698 HCEESGRRVLVYS-CRHGYELQGREQLTCT-QEGWDFQP-PLCKDVNECADGAHPP-CHA 753
HCE+ + S C+ G + CT +G+ C+D+NEC HP C
Sbjct: 1159 HCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECE---HPGLCGP 1215
Query: 754 SARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C NT+G F C+C + + DGRTC D
Sbjct: 1216 QGECLNTEGSFHCVCQQGFSISADGRTCED 1245
Score = 45.1 bits (105), Expect = 3e-04
Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C+D++EC + C + C NT G F+CLC ++ DG+ CVD
Sbjct: 1243 CEDIDECVNNT--VCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVD 1287
Score = 44.7 bits (104), Expect = 4e-04
Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 5/76 (6%)
Query: 711 CRHGYELQGREQLTCT-QEGWDF--QPPLCKDVNECADGAHPPCHASARCRNTKGGFQCL 767
C G+ + + TC EG+ F Q C D++EC H + RC NT+G F C+
Sbjct: 885 CGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQH--LCSQGRCENTEGSFLCI 942
Query: 768 CADPYELGDDGRTCVD 783
C + ++G C+D
Sbjct: 943 CPAGFMASEEGTNCID 958
Score = 43.9 bits (102), Expect = 7e-04
Identities = 30/101 (29%), Positives = 41/101 (40%), Gaps = 20/101 (19%)
Query: 683 DKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNE 742
D+C NG + E S R +C GY+L + C+D++E
Sbjct: 1082 DECQQGNLCVNGQCKNTEGSFR----CTCGQGYQLSAAKDQ-------------CEDIDE 1124
Query: 743 CADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C H A +CRNT+G FQC+C Y G C D
Sbjct: 1125 CQ---HRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCED 1162
Score = 42.0 bits (97), Expect = 0.002
Identities = 30/102 (29%), Positives = 38/102 (37%), Gaps = 18/102 (17%)
Query: 681 QDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDV 740
Q ++CG ENG V +E C GY L D C DV
Sbjct: 1622 QAEECGILNGCENGRCVRVQEG----YTCDCFDGYHL-------------DTAKMTCVDV 1664
Query: 741 NECAD-GAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTC 781
NEC + +A+C NT G ++CLC Y D C
Sbjct: 1665 NECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYC 1706
Score = 41.2 bits (95), Expect = 0.004
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 6/75 (8%)
Query: 711 CRHGYELQGREQLTCTQEGWDFQPPL---CKDVNECADGAHPPCHASARCRNTKGGFQCL 767
C++G+ L R C + + P+ C D++EC D P +C NT+G + C
Sbjct: 1437 CKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQD---PSSCIDGQCVNTEGSYNCF 1493
Query: 768 CADPYELGDDGRTCV 782
C P L + C+
Sbjct: 1494 CTHPMVLDASEKRCI 1508
Score = 36.6 bits (83), Expect = 0.10
Identities = 21/61 (34%), Positives = 29/61 (47%), Gaps = 8/61 (13%)
Query: 725 CTQ--EGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCV 782
CT+ GW+ Q C DV+EC + P A+ C N +G + C C Y D + C
Sbjct: 1026 CTEGFRGWNGQ---CLDVDECLE---PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCR 1079
Query: 783 D 783
D
Sbjct: 1080 D 1080
Score = 32.7 bits (73), Expect = 1.5
Identities = 14/50 (28%), Positives = 22/50 (44%), Gaps = 2/50 (4%)
Query: 734 PPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
P ++NEC +P + C N + C+C + Y + R CVD
Sbjct: 869 PTQVTEINECT--VNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVD 916
Score = 31.6 bits (70), Expect = 3.4
Identities = 16/34 (47%), Positives = 19/34 (55%), Gaps = 2/34 (5%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCAD 770
C DVNEC + C A C N +G F C+CAD
Sbjct: 1285 CVDVNEC-ELLSGVC-GEAFCENVEGSFLCVCAD 1316
Score = 31.2 bits (69), Expect = 4.4
Identities = 23/89 (25%), Positives = 37/89 (41%), Gaps = 15/89 (16%)
Query: 681 QDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDV 740
Q+D CG + + F C++ ++ HGY + + C C+D+
Sbjct: 578 QEDCCGTVGT--SWGFNKCQKCPKK----PSYHGYN----QMMECLPGYKRVNNTFCQDI 627
Query: 741 NECA-DGAHPPCHASARCRNTKGGFQCLC 768
NEC G P + C NT G ++C C
Sbjct: 628 NECQLQGVCP----NGECLNTMGSYRCTC 652
Score = 30.8 bits (68), Expect = 5.7
Identities = 17/53 (32%), Positives = 22/53 (41%), Gaps = 9/53 (16%)
Query: 731 DFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
+ Q C +N C +G RC + G+ C C D Y L TCVD
Sbjct: 1620 ELQAEECGILNGCENG---------RCVRVQEGYTCDCFDGYHLDTAKMTCVD 1663
>gi|46249412 latent transforming growth factor beta binding protein
1 isoform LTBP-1S [Homo sapiens]
Length = 1396
Score = 50.4 bits (119), Expect = 7e-06
Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 7/90 (7%)
Query: 698 HCEESGRRVLVYS-CRHGYELQGREQLTCT-QEGWDFQP-PLCKDVNECADGAHPP-CHA 753
HCE+ + S C+ G + CT +G+ C+D+NEC HP C
Sbjct: 833 HCEDINECLEDKSVCQRGDCINTAGSYDCTCPDGFQLDDNKTCQDINECE---HPGLCGP 889
Query: 754 SARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C NT+G F C+C + + DGRTC D
Sbjct: 890 QGECLNTEGSFHCVCQQGFSISADGRTCED 919
Score = 45.1 bits (105), Expect = 3e-04
Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C+D++EC + C + C NT G F+CLC ++ DG+ CVD
Sbjct: 917 CEDIDECVNNT--VCDSHGFCDNTAGSFRCLCYQGFQAPQDGQGCVD 961
Score = 44.7 bits (104), Expect = 4e-04
Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 5/76 (6%)
Query: 711 CRHGYELQGREQLTCT-QEGWDF--QPPLCKDVNECADGAHPPCHASARCRNTKGGFQCL 767
C G+ + + TC EG+ F Q C D++EC H + RC NT+G F C+
Sbjct: 559 CGAGHCINLPVRYTCICYEGYRFSEQQRKCVDIDECTQVQH--LCSQGRCENTEGSFLCI 616
Query: 768 CADPYELGDDGRTCVD 783
C + ++G C+D
Sbjct: 617 CPAGFMASEEGTNCID 632
Score = 43.9 bits (102), Expect = 7e-04
Identities = 30/101 (29%), Positives = 41/101 (40%), Gaps = 20/101 (19%)
Query: 683 DKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDVNE 742
D+C NG + E S R +C GY+L + C+D++E
Sbjct: 756 DECQQGNLCVNGQCKNTEGSFR----CTCGQGYQLSAAKDQ-------------CEDIDE 798
Query: 743 CADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
C H A +CRNT+G FQC+C Y G C D
Sbjct: 799 CQ---HRHLCAHGQCRNTEGSFQCVCDQGYRASGLGDHCED 836
Score = 42.0 bits (97), Expect = 0.002
Identities = 30/102 (29%), Positives = 38/102 (37%), Gaps = 18/102 (17%)
Query: 681 QDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDV 740
Q ++CG ENG V +E C GY L D C DV
Sbjct: 1296 QAEECGILNGCENGRCVRVQEG----YTCDCFDGYHL-------------DTAKMTCVDV 1338
Query: 741 NECAD-GAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTC 781
NEC + +A+C NT G ++CLC Y D C
Sbjct: 1339 NECDELNNRMSLCKNAKCINTDGSYKCLCLPGYVPSDKPNYC 1380
Score = 41.2 bits (95), Expect = 0.004
Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 6/75 (8%)
Query: 711 CRHGYELQGREQLTCTQEGWDFQPPL---CKDVNECADGAHPPCHASARCRNTKGGFQCL 767
C++G+ L R C + + P+ C D++EC D P +C NT+G + C
Sbjct: 1111 CKNGFCLNTRPGYECYCKQGTYYDPVKLQCFDMDECQD---PSSCIDGQCVNTEGSYNCF 1167
Query: 768 CADPYELGDDGRTCV 782
C P L + C+
Sbjct: 1168 CTHPMVLDASEKRCI 1182
Score = 36.6 bits (83), Expect = 0.10
Identities = 21/61 (34%), Positives = 29/61 (47%), Gaps = 8/61 (13%)
Query: 725 CTQ--EGWDFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCV 782
CT+ GW+ Q C DV+EC + P A+ C N +G + C C Y D + C
Sbjct: 700 CTEGFRGWNGQ---CLDVDECLE---PNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCR 753
Query: 783 D 783
D
Sbjct: 754 D 754
Score = 32.7 bits (73), Expect = 1.5
Identities = 14/50 (28%), Positives = 22/50 (44%), Gaps = 2/50 (4%)
Query: 734 PPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
P ++NEC +P + C N + C+C + Y + R CVD
Sbjct: 543 PTQVTEINECT--VNPDICGAGHCINLPVRYTCICYEGYRFSEQQRKCVD 590
Score = 31.6 bits (70), Expect = 3.4
Identities = 16/34 (47%), Positives = 19/34 (55%), Gaps = 2/34 (5%)
Query: 737 CKDVNECADGAHPPCHASARCRNTKGGFQCLCAD 770
C DVNEC + C A C N +G F C+CAD
Sbjct: 959 CVDVNEC-ELLSGVC-GEAFCENVEGSFLCVCAD 990
Score = 31.2 bits (69), Expect = 4.4
Identities = 23/89 (25%), Positives = 37/89 (41%), Gaps = 15/89 (16%)
Query: 681 QDDKCGFPESVENGDFVHCEESGRRVLVYSCRHGYELQGREQLTCTQEGWDFQPPLCKDV 740
Q+D CG + + F C++ ++ HGY + + C C+D+
Sbjct: 252 QEDCCGTVGT--SWGFNKCQKCPKK----PSYHGYN----QMMECLPGYKRVNNTFCQDI 301
Query: 741 NECA-DGAHPPCHASARCRNTKGGFQCLC 768
NEC G P + C NT G ++C C
Sbjct: 302 NECQLQGVCP----NGECLNTMGSYRCTC 326
Score = 30.8 bits (68), Expect = 5.7
Identities = 17/53 (32%), Positives = 22/53 (41%), Gaps = 9/53 (16%)
Query: 731 DFQPPLCKDVNECADGAHPPCHASARCRNTKGGFQCLCADPYELGDDGRTCVD 783
+ Q C +N C +G RC + G+ C C D Y L TCVD
Sbjct: 1294 ELQAEECGILNGCENG---------RCVRVQEGYTCDCFDGYHLDTAKMTCVD 1337
>gi|18104969 prostaglandin-endoperoxide synthase 1 isoform 2
precursor [Homo sapiens]
Length = 562
Score = 50.1 bits (118), Expect = 9e-06
Identities = 39/136 (28%), Positives = 61/136 (44%), Gaps = 9/136 (6%)
Query: 324 LDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPG 383
+D +YG + LERQ + +G L+ G Y P V AP GIP
Sbjct: 227 VDLGHIYGDN--LERQYQLRLFKDGKLKYQVL---DGEMYPPSVE-EAPVLMHYPRGIPP 280
Query: 384 ETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGA 443
+++ G +P L TLWLREHNR+ LKA + W + ++Q R ++
Sbjct: 281 QSQ---MAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIG 337
Query: 444 LHQIITLRDYIPRILG 459
I + +Y+ ++ G
Sbjct: 338 ETIKIVIEEYVQQLSG 353
>gi|18104967 prostaglandin-endoperoxide synthase 1 isoform 1
precursor [Homo sapiens]
Length = 599
Score = 50.1 bits (118), Expect = 9e-06
Identities = 39/136 (28%), Positives = 61/136 (44%), Gaps = 9/136 (6%)
Query: 324 LDASTVYGSSPALERQLRNWTSAEGLLRVHARLRDSGRAYLPFVPPRAPAACAPEPGIPG 383
+D +YG + LERQ + +G L+ G Y P V AP GIP
Sbjct: 227 VDLGHIYGDN--LERQYQLRLFKDGKLKYQVL---DGEMYPPSVE-EAPVLMHYPRGIPP 280
Query: 384 ETRGPCFLAGDGRASEVPSLTALHTLWLREHNRLAAALKALNAHWSADAVYQEARKVVGA 443
+++ G +P L TLWLREHNR+ LKA + W + ++Q R ++
Sbjct: 281 QSQ---MAVGQEVFGLLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRLILIG 337
Query: 444 LHQIITLRDYIPRILG 459
I + +Y+ ++ G
Sbjct: 338 ETIKIVIEEYVQQLSG 353
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.432
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,334,503
Number of Sequences: 37866
Number of extensions: 1819473
Number of successful extensions: 6398
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 136
Number of HSP's successfully gapped in prelim test: 100
Number of HSP's that attempted gapping in prelim test: 4954
Number of HSP's gapped (non-prelim): 1230
length of query: 876
length of database: 18,247,518
effective HSP length: 111
effective length of query: 765
effective length of database: 14,044,392
effective search space: 10743959880
effective search space used: 10743959880
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.