Guide to the Human Genome
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Name: PTGS2 Sequence: fasta or formatted (604aa) NCBI GI: 4506265
Description:

prostaglandin-endoperoxide synthase 2 precursor

Referenced in:

Arachidonate, Prostaglandins, and Leukotrienes
Common Drug Targets

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.1         31           2
 C cysteine            2.2         13           2
 D aspartate           4.3         26           2
 E glutamate           6.0         36           2
 F phenylalanine       6.3         38           2
 G glycine             6.1         37           2
 H histidine           3.1         19           1
 I isoleucine          5.6         34           2
 K lysine              5.6         34           2
 L leucine             9.4         57           3
 M methionine          2.5         15           2
 N asparagine          4.8         29           2
 P proline             6.6         40           2
 Q glutamine           5.1         31           2
 R arginine            4.5         27           2
 S serine              5.8         35           3
 T threonine           5.6         34           1
 V valine              5.8         35           2
 W tryptophan          1.0          6           1
 Y tyrosine            4.5         27           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   prostaglandin-endoperoxide synthase 2 precursor [Homo... 
PTGS1                 0.622   prostaglandin-endoperoxide synthase 1 isoform 1 prec...
PTGS1                 0.573   prostaglandin-endoperoxide synthase 1 isoform 2 prec...
PXDN                  0.029   peroxidasin 
TPO                   0.026   thyroid peroxidase isoform a 
TPO                   0.026   thyroid peroxidase isoform b 
TPO                   0.026   thyroid peroxidase isoform d 
PXDNL                 0.022   peroxidasin homolog-like 
NRXN1                 0.021   neurexin 1 isoform alpha2 precursor 
NRXN1                 0.021   neurexin 1 isoform alpha1 precursor 
LPO                   0.018   lactoperoxidase isoform 3 preproprotein 
LPO                   0.018   lactoperoxidase isoform 1 preproprotein 
DUOX1                 0.018   dual oxidase 1 precursor 
DUOX1                 0.018   dual oxidase 1 precursor 
SLIT2                 0.017   slit homolog 2 
NOTCH2                0.016   notch 2 preproprotein 
NRXN3                 0.016   neurexin 3 isoform 1 precursor 
MPO                   0.016   myeloperoxidase 
DUOX2                 0.015   dual oxidase 2 precursor 
NRXN2                 0.015   neurexin 2 isoform alpha-1 precursor 
NRXN2                 0.015   neurexin 2 isoform alpha-2 precursor 
NOTCH3                0.014   Notch homolog 3 
EYS                   0.014   eyes shut homolog isoform 1 
CRB1                  0.014   crumbs homolog 1 precursor 
DLK1                  0.013   delta-like 1 homolog 
JAG2                  0.012   jagged 2 isoform b precursor 
JAG2                  0.012   jagged 2 isoform a precursor 
JAG1                  0.012   jagged 1 precursor 
NOTCH1                0.012   notch1 preproprotein 
VWA2                  0.012   von Willebrand factor A domain containing 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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