Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 28274705
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28274705 family with sequence similarity 9, member A [Homo
sapiens]
(332 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28274705 family with sequence similarity 9, member A [Homo sa... 651 0.0
gi|45504371 family with sequence similarity 9, member B [Homo sa... 197 1e-50
gi|28274703 family with sequence similarity 9, member C [Homo sa... 152 3e-37
gi|17975763 myelin transcription factor 1 [Homo sapiens] 75 8e-14
gi|21735415 centromere protein B [Homo sapiens] 75 1e-13
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 74 2e-13
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 74 2e-13
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 74 2e-13
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 74 2e-13
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 74 2e-13
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 74 2e-13
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 74 2e-13
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 74 2e-13
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 72 9e-13
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 71 2e-12
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 70 2e-12
gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens] 69 4e-12
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 66 4e-11
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 66 5e-11
gi|221219020 NYD-SP11 protein [Homo sapiens] 65 6e-11
gi|24415404 MDN1, midasin homolog [Homo sapiens] 65 1e-10
gi|169210053 PREDICTED: hypothetical protein [Homo sapiens] 64 2e-10
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 63 3e-10
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 63 3e-10
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 63 3e-10
gi|157738619 smoothelin-like 1 [Homo sapiens] 62 5e-10
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof... 62 7e-10
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 62 9e-10
gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapi... 61 1e-09
gi|22749303 hypothetical protein LOC196477 [Homo sapiens] 61 1e-09
>gi|28274705 family with sequence similarity 9, member A [Homo
sapiens]
Length = 332
Score = 651 bits (1679), Expect = 0.0
Identities = 332/332 (100%), Positives = 332/332 (100%)
Query: 1 MEPVGRKRSRKAAKAQLEAQVTAAQGATKEGSGIASNFPGQPTMEPVGRKRSRKAAKAQL 60
MEPVGRKRSRKAAKAQLEAQVTAAQGATKEGSGIASNFPGQPTMEPVGRKRSRKAAKAQL
Sbjct: 1 MEPVGRKRSRKAAKAQLEAQVTAAQGATKEGSGIASNFPGQPTMEPVGRKRSRKAAKAQL 60
Query: 61 EAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDEHGEREPFAEKDEHTGIHTMKL 120
EAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDEHGEREPFAEKDEHTGIHTMKL
Sbjct: 61 EAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDEHGEREPFAEKDEHTGIHTMKL 120
Query: 121 EHIAADIKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLKRQKRDYRHTRKLLNVLKE 180
EHIAADIKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLKRQKRDYRHTRKLLNVLKE
Sbjct: 121 EHIAADIKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLKRQKRDYRHTRKLLNVLKE 180
Query: 181 YIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEG 240
YIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEG
Sbjct: 181 YIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEG 240
Query: 241 EEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQKRWQQPTGVRSWRLRE 300
EEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQKRWQQPTGVRSWRLRE
Sbjct: 241 EEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQKRWQQPTGVRSWRLRE 300
Query: 301 MKPLLEQLLKAAKDTKDNYCIISSSEESELDN 332
MKPLLEQLLKAAKDTKDNYCIISSSEESELDN
Sbjct: 301 MKPLLEQLLKAAKDTKDNYCIISSSEESELDN 332
>gi|45504371 family with sequence similarity 9, member B [Homo
sapiens]
Length = 186
Score = 197 bits (500), Expect = 1e-50
Identities = 125/267 (46%), Positives = 145/267 (54%), Gaps = 82/267 (30%)
Query: 66 AAPAKKHTGKDPVRDECEERNPFTETREEDVTDEHGEREPFAEKDEHTGIHTMKLEHIAA 125
AA KKH GKDPVRDECEERN FTETREEDVTDEHGEREPFAE DEHTG +T K E A
Sbjct: 2 AAWGKKHAGKDPVRDECEERNRFTETREEDVTDEHGEREPFAETDEHTGANTKKPEDTAE 61
Query: 126 DIKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLKRQKRDYRHTRKLLNVLKEYIAEK 185
D L AKR+ +K+DK KTKN + AL+KKQLKRQKRDY H+ KLLNVL+EYI +
Sbjct: 62 D----LTAKRKRMKMDKTC-SKTKNKSKHALRKKQLKRQKRDYIHSLKLLNVLEEYITD- 115
Query: 186 QKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGG 245
E+KEEEEEEG
Sbjct: 116 ---------------------------------------------EQKEEEEEEG----- 125
Query: 246 GEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQKRWQQPTGVRSWRLREMKPLL 305
EEEE I+ FQE+QK+WQQ VR RL+EMK L
Sbjct: 126 --------------------------EEEELIRIFQEQQKKWQQYRSVRRERLKEMKLLR 159
Query: 306 EQLLKAAKDTKDNYCIISSSEESELDN 332
+Q +KA +D +D + S E+SELDN
Sbjct: 160 DQFVKALEDFEDLCDRVFSDEDSELDN 186
>gi|28274703 family with sequence similarity 9, member C [Homo
sapiens]
Length = 166
Score = 152 bits (385), Expect = 3e-37
Identities = 82/138 (59%), Positives = 99/138 (71%)
Query: 55 AAKAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDEHGEREPFAEKDEHTG 114
AAK QLE QV AA + GKDPV E EER P TET+E DVTDEHGER FAE DEHTG
Sbjct: 2 AAKDQLEVQVMAAQEMELAGKDPVSHEHEERKPVTETKEGDVTDEHGERGSFAETDEHTG 61
Query: 115 IHTMKLEHIAADIKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLKRQKRDYRHTRKL 174
+ T +LE IAADIK+ LAAKR+ I+ A + KN I+ L+ QLKRQKRDYR + KL
Sbjct: 62 VDTKELEDIAADIKEHLAAKRKRIEKIAKACSEIKNRIKNVLRTTQLKRQKRDYRISLKL 121
Query: 175 LNVLKEYIAEKQKDDEAE 192
NVL+E+I ++QKD+E +
Sbjct: 122 PNVLEEFITDEQKDEEGD 139
Score = 45.8 bits (107), Expect = 5e-05
Identities = 19/29 (65%), Positives = 26/29 (89%)
Query: 261 TEEEEEEEEEEEEEEQIKAFQEKQKRWQQ 289
T+E+++EE + E+EEQIK FQE+QKRWQQ
Sbjct: 130 TDEQKDEEGDGEKEEQIKIFQEQQKRWQQ 158
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 75.1 bits (183), Expect = 8e-14
Identities = 46/100 (46%), Positives = 61/100 (61%), Gaps = 5/100 (5%)
Query: 183 AEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEE 242
AE+ + E ++ + AA+E ++ ++ E+E+EEE+EEEEE+EE+EEE EE
Sbjct: 221 AEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEE 280
Query: 243 EGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQE 282
E EE EE E EE EEEEEEEEEEEE FQE
Sbjct: 281 EEEEEEEEE-----EEEEEEEEEEEEEEEEEAAPDVIFQE 315
Score = 64.7 bits (156), Expect = 1e-10
Identities = 41/105 (39%), Positives = 57/105 (54%), Gaps = 20/105 (19%)
Query: 186 QKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVI-----VVEDEEEEEKEEEEEKEEEEEEG 240
Q +D E E ++ AA+E ++ EEE+E+EEEEE+EEEE+E
Sbjct: 217 QPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEE 276
Query: 241 EEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQK 285
EEE EE EEEEEEEEEEEEEE+ + +E+++
Sbjct: 277 EEE---------------EEEEEEEEEEEEEEEEEEEEEEEEEEE 306
Score = 48.5 bits (114), Expect = 8e-06
Identities = 29/115 (25%), Positives = 57/115 (49%), Gaps = 2/115 (1%)
Query: 177 VLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEE 236
+ +E + E+ A+ + AA A+ + + ++ E+ EE E + +
Sbjct: 174 IAEETLVEEDLGQAAKPGPGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQ 233
Query: 237 E--EEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQKRWQQ 289
+ + E+ EE + G EE +EEEEEEEEEEEE++ + +E+++ ++
Sbjct: 234 DLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEE 288
Score = 48.5 bits (114), Expect = 8e-06
Identities = 33/99 (33%), Positives = 52/99 (52%), Gaps = 9/99 (9%)
Query: 200 AAEAAAAAEAAAA-------AAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGG--GEEGE 250
AAE AA+ E A EV+ V E ++ + ++ EE ++ G E E
Sbjct: 201 AAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEE 260
Query: 251 EGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQKRWQQ 289
+ E EE EE+EEEEEEEEEEE+ + +E+++ ++
Sbjct: 261 DEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEE 299
Score = 36.2 bits (82), Expect = 0.042
Identities = 20/55 (36%), Positives = 29/55 (52%)
Query: 179 KEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEK 233
K ++ +++D+E EE E E E E E+EEEEE+EEEEE+
Sbjct: 252 KGILSHEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE 306
Score = 31.2 bits (69), Expect = 1.3
Identities = 28/137 (20%), Positives = 50/137 (36%)
Query: 184 EKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEE 243
E ++++E EE E E E E E+EEEEE+EEE + +E
Sbjct: 260 EDEEEEEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSH 319
Query: 244 GGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQKRWQQPTGVRSWRLREMKP 303
++ E G E E ++++ + ++ + ++ R
Sbjct: 320 TSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTHSRKSTVTDESEMQDMMTRGNLG 379
Query: 304 LLEQLLKAAKDTKDNYC 320
LLEQ + + C
Sbjct: 380 LLEQAIALKAEQVRTVC 396
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 74.7 bits (182), Expect = 1e-13
Identities = 48/103 (46%), Positives = 59/103 (57%), Gaps = 5/103 (4%)
Query: 192 EEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEE 251
E ++ AA EA A + E EEEEE+EEEEE+EE E E EEE G EE EE
Sbjct: 376 EPSDIAACFREAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEE 435
Query: 252 GGGGGE-GEETEEEEE----EEEEEEEEEQIKAFQEKQKRWQQ 289
GG G E GEE E EEE +EEEEE+E+ + + + W Q
Sbjct: 436 GGEGEELGEEEEVEEEGDVDSDEEEEEDEESSSEGLEAEDWAQ 478
Score = 51.6 bits (122), Expect = 1e-06
Identities = 35/120 (29%), Positives = 55/120 (45%), Gaps = 29/120 (24%)
Query: 184 EKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEE 243
E+++++E EE E E E E+ E+EE EE+ + + EEEEE+ E
Sbjct: 410 EEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEEL--GEEEEVEEEGDVDSDEEEEEDEESS 467
Query: 244 GGGEEGE-------EGGG--------------------GGEGEETEEEEEEEEEEEEEEQ 276
G E E E GG GGE +++ EEE++EEE++E++
Sbjct: 468 SEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDE 527
Score = 37.0 bits (84), Expect = 0.024
Identities = 25/66 (37%), Positives = 33/66 (50%), Gaps = 8/66 (12%)
Query: 250 EEGGGGGEG--------EETEEEEEEEEEEEEEEQIKAFQEKQKRWQQPTGVRSWRLREM 301
E G GGG E EEEEEEEEEEEEEE +E++ ++ G L E
Sbjct: 386 EAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEE 445
Query: 302 KPLLEQ 307
+ + E+
Sbjct: 446 EEVEEE 451
Score = 34.3 bits (77), Expect = 0.16
Identities = 20/79 (25%), Positives = 37/79 (46%), Gaps = 9/79 (11%)
Query: 184 EKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVED---------EEEEEKEEEEEKE 234
E++++DE +E A A EA + E+ E E+ + + E+E
Sbjct: 458 EEEEEDEESSSEGLEAEDWAQGVVEAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEE 517
Query: 235 EEEEEGEEEGGGEEGEEGG 253
++EEE +E+ ++ EE G
Sbjct: 518 DDEEEDDEDEDDDDDEEDG 536
Score = 33.9 bits (76), Expect = 0.21
Identities = 14/57 (24%), Positives = 31/57 (54%)
Query: 195 EAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEE 251
EA + A EA + ++ + + EEE+++EE++E+ +++ E+G+E
Sbjct: 482 EAGGSFGAYGAQEEAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 73.6 bits (179), Expect = 2e-13
Identities = 65/242 (26%), Positives = 109/242 (45%), Gaps = 18/242 (7%)
Query: 49 RKRSRKA---AKAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDEHGEREP 105
RKR R+ A+ + E Q R A++H+ ++ R E ER E + + E E++
Sbjct: 122 RKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKE 181
Query: 106 FAEKDEHTGIHTMKLEHIAAD---IKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLK 162
+ E ++A +++ + K + ++ R + E +K +K
Sbjct: 182 RERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVK 241
Query: 163 RQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDE 222
+K + R LL+ L++ D E + + A +++AE+ + +E E E+E
Sbjct: 242 EEKME---ERDLLSDLQDI-----SDSERKTSSAESSSAESGSGSEEEEEEEE----EEE 289
Query: 223 EEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQE 282
EE EE E+EEEEEE EEE G EE E +EEE E+EE E E + E
Sbjct: 290 EEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPE 349
Query: 283 KQ 284
+
Sbjct: 350 SR 351
Score = 55.8 bits (133), Expect = 5e-08
Identities = 59/266 (22%), Positives = 117/266 (43%), Gaps = 20/266 (7%)
Query: 36 SNFPGQPTMEPVGRKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTETREED 95
S + + +ME G + A K Q + K H KD R E + ++ + RE +
Sbjct: 65 SPYRREDSMEDRGEEDDSLAIKPP---QQMSRKEKVHHRKDEKRKE-KWKHARVKEREHE 120
Query: 96 VTDEHGEREPFAEKD-EHTGIHTMKLEHIAADIKKGLAAKREMIKIDKAAYRKTKNTIER 154
H E + A ++ E M EH ++RE ++++ ++ + R
Sbjct: 121 RRKRHREEQDKARREWERQKRREMAREH----------SRRERDRLEQLERKRERERKMR 170
Query: 155 ALKKKQLKRQKRDYR--HTRKLLNVLKEYIAEKQ--KDDEAEEAEAAA-AAAEAAAAAEA 209
+K+Q ++++R+ R RK +E A + ++D +++ +A+ + + E
Sbjct: 171 EQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRER 230
Query: 210 AAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEE 269
V++E+ EE++ + ++ + + E G G EE EEEEEEEE
Sbjct: 231 FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEE 290
Query: 270 EEEEEEQIKAFQEKQKRWQQPTGVRS 295
E E+ + +E+++ ++ TG S
Sbjct: 291 EGSTSEESEEEEEEEEEEEEETGSNS 316
Score = 39.3 bits (90), Expect = 0.005
Identities = 47/217 (21%), Positives = 87/217 (40%), Gaps = 23/217 (10%)
Query: 49 RKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDE----HGERE 104
R+R RK + Q E + + ++ + R+ E + T ED +D+ H R
Sbjct: 163 RERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRS 222
Query: 105 PFAEKDEHTGIHTMKLEHIAADIKKGLAAKREMI---KIDKAAYRKTKNTIERALKKKQL 161
P E +L +K+ +R+++ + + RKT + + +
Sbjct: 223 PPRPPRER-----FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSG 277
Query: 162 KRQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVED 221
++ + + E E+++++E EE E + + EA+ + A EV E
Sbjct: 278 SEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQS-----AEEVSEEEM 332
Query: 222 EEEEEKEEEE------EKEEEEEEGEEEGGGEEGEEG 252
E+EE+E E E + + GE E EE EG
Sbjct: 333 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEG 369
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 73.6 bits (179), Expect = 2e-13
Identities = 65/242 (26%), Positives = 109/242 (45%), Gaps = 18/242 (7%)
Query: 49 RKRSRKA---AKAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDEHGEREP 105
RKR R+ A+ + E Q R A++H+ ++ R E ER E + + E E++
Sbjct: 132 RKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKE 191
Query: 106 FAEKDEHTGIHTMKLEHIAAD---IKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLK 162
+ E ++A +++ + K + ++ R + E +K +K
Sbjct: 192 RERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVK 251
Query: 163 RQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDE 222
+K + R LL+ L++ D E + + A +++AE+ + +E E E+E
Sbjct: 252 EEKME---ERDLLSDLQDI-----SDSERKTSSAESSSAESGSGSEEEEEEEE----EEE 299
Query: 223 EEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQE 282
EE EE E+EEEEEE EEE G EE E +EEE E+EE E E + E
Sbjct: 300 EEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPE 359
Query: 283 KQ 284
+
Sbjct: 360 SR 361
Score = 53.5 bits (127), Expect = 3e-07
Identities = 61/275 (22%), Positives = 116/275 (42%), Gaps = 28/275 (10%)
Query: 36 SNFPGQPTMEPVGRKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDE-CEERNPFTE---- 90
S + + +ME G + A K Q + K H KD R E C + E
Sbjct: 65 SPYRREDSMEDRGEEDDSLAIKPP---QQMSRKEKVHHRKDEKRKEKCRHHSHSAEGGKH 121
Query: 91 ----TREEDVTDEHGEREPFAEKD-EHTGIHTMKLEHIAADIKKGLAAKREMIKIDKAAY 145
RE + H E + A ++ E M EH ++RE ++++
Sbjct: 122 ARVKEREHERRKRHREEQDKARREWERQKRREMAREH----------SRRERDRLEQLER 171
Query: 146 RKTKNTIERALKKKQLKRQKRDYR--HTRKLLNVLKEYIAEKQ--KDDEAEEAEAAA-AA 200
++ + R +K+Q ++++R+ R RK +E A + ++D +++ +A+ +
Sbjct: 172 KRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSR 231
Query: 201 AEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEE 260
+ E V++E+ EE++ + ++ + + E G G EE
Sbjct: 232 SPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEE 291
Query: 261 TEEEEEEEEEEEEEEQIKAFQEKQKRWQQPTGVRS 295
EEEEEEEEE E+ + +E+++ ++ TG S
Sbjct: 292 EEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNS 326
Score = 39.3 bits (90), Expect = 0.005
Identities = 47/217 (21%), Positives = 87/217 (40%), Gaps = 23/217 (10%)
Query: 49 RKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDE----HGERE 104
R+R RK + Q E + + ++ + R+ E + T ED +D+ H R
Sbjct: 173 RERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRS 232
Query: 105 PFAEKDEHTGIHTMKLEHIAADIKKGLAAKREMI---KIDKAAYRKTKNTIERALKKKQL 161
P E +L +K+ +R+++ + + RKT + + +
Sbjct: 233 PPRPPRER-----FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSG 287
Query: 162 KRQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVED 221
++ + + E E+++++E EE E + + EA+ + A EV E
Sbjct: 288 SEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQS-----AEEVSEEEM 342
Query: 222 EEEEEKEEEE------EKEEEEEEGEEEGGGEEGEEG 252
E+EE+E E E + + GE E EE EG
Sbjct: 343 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEG 379
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 73.6 bits (179), Expect = 2e-13
Identities = 50/158 (31%), Positives = 83/158 (52%), Gaps = 6/158 (3%)
Query: 131 LAAKREMIKIDKAAYRKTKNTIERALKKKQLKRQKRDYRHTRKLLNVLKEYIAEKQKDDE 190
+++K + K++ + +E +++ +++ +K + + +++K +
Sbjct: 432 ISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEA 491
Query: 191 AEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGE 250
AEE E A E AA+ + A V+ EEE EKEEEE +EEEEEE +E ++ E
Sbjct: 492 AEEKEEEPEAEEEEVAAKKSPVKATAPEVK-EEEGEKEEEEGQEEEEEE-DEGAKSDQAE 549
Query: 251 EGG----GGGEGEETEEEEEEEEEEEEEEQIKAFQEKQ 284
EGG G E EE E+EE E E E E E+ +A +EK+
Sbjct: 550 EGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKK 587
Score = 66.2 bits (160), Expect = 4e-11
Identities = 41/106 (38%), Positives = 57/106 (53%), Gaps = 1/106 (0%)
Query: 179 KEYIAEKQKDDEAEEAEAAAAAAEAAAAA-EAAAAAAEVIVVEDEEEEEKEEEEEKEEEE 237
KE EK+++ EAEE E AA + A A E E E +EEEE+E+E K ++
Sbjct: 489 KEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQA 548
Query: 238 EEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEK 283
EEG E G +E G EGE E E EE E +EE++++ E+
Sbjct: 549 EEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEE 594
Score = 58.2 bits (139), Expect = 1e-08
Identities = 56/246 (22%), Positives = 110/246 (44%), Gaps = 13/246 (5%)
Query: 47 VGRKRSRKAAKAQLEAQVRAAP---AKKHTGKDPVRDECEERNPFTETREEDVTDEHGER 103
V K A K +L A + AK K PV ++ ++P ++ E+ +
Sbjct: 588 VEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEK--GKSPVPKSPVEEKGKSPVPK 645
Query: 104 EPFAEKDEHTGIHTMKLEHIAADIKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLKR 163
P EK + + E + + K ++ + K+ + K+ E K +Q +
Sbjct: 646 SPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVG-KGEQKEE 704
Query: 164 QKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEE 223
++++ + K V K+ E++ D E+ +A + E A A + + +E E
Sbjct: 705 EEKEVKEAPKEEKVEKK---EEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKET 761
Query: 224 EEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEE----TEEEEEEEEEEEEEEQIKA 279
+EE + ++++E+E+ G E G EEG + G G +E E E +EE E+E ++ +
Sbjct: 762 KEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGS 821
Query: 280 FQEKQK 285
+E++K
Sbjct: 822 GREEEK 827
Score = 44.7 bits (104), Expect = 1e-04
Identities = 42/174 (24%), Positives = 76/174 (43%), Gaps = 6/174 (3%)
Query: 115 IHTMKLEHIAADIKKGLAAKREMIKIDKAAYRKT---KNTIERALKKKQLKRQKRDYRHT 171
I K+E +++++ L A E + + +K + E +++++ +K + T
Sbjct: 457 IEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKAT 516
Query: 172 RKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEE 231
+KE EK++++ EE E A++ A E + E+ E+EE E E
Sbjct: 517 AP---EVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEA 573
Query: 232 EKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQK 285
E E EE E +EE EE E E + + E+ E+ + +EK K
Sbjct: 574 EAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGK 627
Score = 41.2 bits (95), Expect = 0.001
Identities = 53/240 (22%), Positives = 93/240 (38%), Gaps = 26/240 (10%)
Query: 46 PVGRKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDEHGEREP 105
PV K K+ +E + K K PV ++ + P + E E G+ E
Sbjct: 647 PVEEKGKSPVPKSPVEEK-----GKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQ 701
Query: 106 FAEKDEHTGIHTMKLEHIAADIKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLKRQK 165
E+++ + K+ K+E D +K ++ ++ + + K
Sbjct: 702 KEEEEKE----------VKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITK 751
Query: 166 RDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEE 225
H K KE Q++ E E+A + E + A + E I V E E
Sbjct: 752 SVKVHLEK---ETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEG 808
Query: 226 EKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQK 285
KEE E+E +E+G G E EE G G + +E++ ++ EE++ + +K
Sbjct: 809 -------KEEVEQETKEKGSGRE-EEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEK 860
Score = 37.0 bits (84), Expect = 0.024
Identities = 54/286 (18%), Positives = 112/286 (39%), Gaps = 32/286 (11%)
Query: 47 VGRKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDEHGEREPF 106
V K +K A + E + A + K PV+ E + E + +E G+ E
Sbjct: 482 VSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPE----VKEEEGEKEEEEGQEE-- 535
Query: 107 AEKDEHTGIHTMKLEHIAADIKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLKRQKR 166
E++E G + + E ++ K+G + K E + + + + A ++K+++ +
Sbjct: 536 -EEEEDEGAKSDQAEEGGSE-KEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSE 593
Query: 167 DYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVI------VVE 220
+ KE + K ++ E+A++ + ++ + V V +
Sbjct: 594 EV--------ATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPK 645
Query: 221 DEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEE----------EEEEEE 270
EE+ + K EE+G+ EE + EE E++EEE
Sbjct: 646 SPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEE 705
Query: 271 EEEEEQIKAFQEKQKRWQQPTGVRSWRLREMKPLLEQLLKAAKDTK 316
E+E ++ ++ +K+ ++P V + E E + + TK
Sbjct: 706 EKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITK 751
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 73.6 bits (179), Expect = 2e-13
Identities = 50/158 (31%), Positives = 83/158 (52%), Gaps = 6/158 (3%)
Query: 131 LAAKREMIKIDKAAYRKTKNTIERALKKKQLKRQKRDYRHTRKLLNVLKEYIAEKQKDDE 190
+++K + K++ + +E +++ +++ +K + + +++K +
Sbjct: 56 ISSKIQKPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEA 115
Query: 191 AEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGE 250
AEE E A E AA+ + A V+ EEE EKEEEE +EEEEEE +E ++ E
Sbjct: 116 AEEKEEEPEAEEEEVAAKKSPVKATAPEVK-EEEGEKEEEEGQEEEEEE-DEGAKSDQAE 173
Query: 251 EGG----GGGEGEETEEEEEEEEEEEEEEQIKAFQEKQ 284
EGG G E EE E+EE E E E E E+ +A +EK+
Sbjct: 174 EGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKK 211
Score = 66.2 bits (160), Expect = 4e-11
Identities = 41/106 (38%), Positives = 57/106 (53%), Gaps = 1/106 (0%)
Query: 179 KEYIAEKQKDDEAEEAEAAAAAAEAAAAA-EAAAAAAEVIVVEDEEEEEKEEEEEKEEEE 237
KE EK+++ EAEE E AA + A A E E E +EEEE+E+E K ++
Sbjct: 113 KEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQA 172
Query: 238 EEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEK 283
EEG E G +E G EGE E E EE E +EE++++ E+
Sbjct: 173 EEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEE 218
Score = 58.2 bits (139), Expect = 1e-08
Identities = 56/246 (22%), Positives = 110/246 (44%), Gaps = 13/246 (5%)
Query: 47 VGRKRSRKAAKAQLEAQVRAAP---AKKHTGKDPVRDECEERNPFTETREEDVTDEHGER 103
V K A K +L A + AK K PV ++ ++P ++ E+ +
Sbjct: 212 VEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEK--GKSPVPKSPVEEKGKSPVPK 269
Query: 104 EPFAEKDEHTGIHTMKLEHIAADIKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLKR 163
P EK + + E + + K ++ + K+ + K+ E K +Q +
Sbjct: 270 SPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVG-KGEQKEE 328
Query: 164 QKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEE 223
++++ + K V K+ E++ D E+ +A + E A A + + +E E
Sbjct: 329 EEKEVKEAPKEEKVEKK---EEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKET 385
Query: 224 EEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEE----TEEEEEEEEEEEEEEQIKA 279
+EE + ++++E+E+ G E G EEG + G G +E E E +EE E+E ++ +
Sbjct: 386 KEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGS 445
Query: 280 FQEKQK 285
+E++K
Sbjct: 446 GREEEK 451
Score = 44.7 bits (104), Expect = 1e-04
Identities = 42/174 (24%), Positives = 76/174 (43%), Gaps = 6/174 (3%)
Query: 115 IHTMKLEHIAADIKKGLAAKREMIKIDKAAYRKT---KNTIERALKKKQLKRQKRDYRHT 171
I K+E +++++ L A E + + +K + E +++++ +K + T
Sbjct: 81 IEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKAT 140
Query: 172 RKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEE 231
+KE EK++++ EE E A++ A E + E+ E+EE E E
Sbjct: 141 AP---EVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEEGETEA 197
Query: 232 EKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQK 285
E E EE E +EE EE E E + + E+ E+ + +EK K
Sbjct: 198 EAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGK 251
Score = 41.2 bits (95), Expect = 0.001
Identities = 53/240 (22%), Positives = 93/240 (38%), Gaps = 26/240 (10%)
Query: 46 PVGRKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDEHGEREP 105
PV K K+ +E + K K PV ++ + P + E E G+ E
Sbjct: 271 PVEEKGKSPVPKSPVEEK-----GKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQ 325
Query: 106 FAEKDEHTGIHTMKLEHIAADIKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLKRQK 165
E+++ + K+ K+E D +K ++ ++ + + K
Sbjct: 326 KEEEEKE----------VKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITK 375
Query: 166 RDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEE 225
H K KE Q++ E E+A + E + A + E I V E E
Sbjct: 376 SVKVHLEK---ETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEG 432
Query: 226 EKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQK 285
KEE E+E +E+G G E EE G G + +E++ ++ EE++ + +K
Sbjct: 433 -------KEEVEQETKEKGSGRE-EEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEK 484
Score = 37.0 bits (84), Expect = 0.024
Identities = 54/286 (18%), Positives = 112/286 (39%), Gaps = 32/286 (11%)
Query: 47 VGRKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDEHGEREPF 106
V K +K A + E + A + K PV+ E + E + +E G+ E
Sbjct: 106 VSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPE----VKEEEGEKEEEEGQEE-- 159
Query: 107 AEKDEHTGIHTMKLEHIAADIKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLKRQKR 166
E++E G + + E ++ K+G + K E + + + + A ++K+++ +
Sbjct: 160 -EEEEDEGAKSDQAEEGGSE-KEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSE 217
Query: 167 DYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVI------VVE 220
+ KE + K ++ E+A++ + ++ + V V +
Sbjct: 218 EV--------ATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPK 269
Query: 221 DEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEE----------EEEEEE 270
EE+ + K EE+G+ EE + EE E++EEE
Sbjct: 270 SPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEE 329
Query: 271 EEEEEQIKAFQEKQKRWQQPTGVRSWRLREMKPLLEQLLKAAKDTK 316
E+E ++ ++ +K+ ++P V + E E + + TK
Sbjct: 330 EKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITK 375
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 73.6 bits (179), Expect = 2e-13
Identities = 65/242 (26%), Positives = 109/242 (45%), Gaps = 18/242 (7%)
Query: 49 RKRSRKA---AKAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDEHGEREP 105
RKR R+ A+ + E Q R A++H+ ++ R E ER E + + E E++
Sbjct: 123 RKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKE 182
Query: 106 FAEKDEHTGIHTMKLEHIAAD---IKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLK 162
+ E ++A +++ + K + ++ R + E +K +K
Sbjct: 183 RERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVK 242
Query: 163 RQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDE 222
+K + R LL+ L++ D E + + A +++AE+ + +E E E+E
Sbjct: 243 EEKME---ERDLLSDLQDI-----SDSERKTSSAESSSAESGSGSEEEEEEEE----EEE 290
Query: 223 EEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQE 282
EE EE E+EEEEEE EEE G EE E +EEE E+EE E E + E
Sbjct: 291 EEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPE 350
Query: 283 KQ 284
+
Sbjct: 351 SR 352
Score = 60.5 bits (145), Expect = 2e-09
Identities = 67/271 (24%), Positives = 105/271 (38%), Gaps = 36/271 (13%)
Query: 36 SNFPGQPTMEPVGRKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTETREED 95
S + + +ME G + A K Q + K H KD R E + + RE +
Sbjct: 65 SPYRREDSMEDRGEEDDSLAIKPP---QQMSRKEKVHHRKDEKRKEKKHARVKEKEREHE 121
Query: 96 VTDEHGEREPFAEKD-EHTGIHTMKLEHIAA--DIKKGLAAKREMIKIDKAAYRKTKNTI 152
H E + A ++ E M EH D + L KRE + + ++ +
Sbjct: 122 RRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQK 181
Query: 153 ERALKKKQLKRQKRDYRHTRKLLNVLKEYIAEKQK------------------------- 187
ER + ++ ++++ R ++E ++K K
Sbjct: 182 ERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPV 241
Query: 188 DDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEE-----EEGEE 242
+E E + + + +E ++AE E E+EEEEE+EEEE EE EE
Sbjct: 242 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 301
Query: 243 EGGGEEGEEGGGGGEGEETEEEEEEEEEEEE 273
E EE EE G EE E+ EE EEE
Sbjct: 302 EEEEEEEEEEETGSNSEEASEQSAEEVSEEE 332
Score = 39.3 bits (90), Expect = 0.005
Identities = 47/217 (21%), Positives = 87/217 (40%), Gaps = 23/217 (10%)
Query: 49 RKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDE----HGERE 104
R+R RK + Q E + + ++ + R+ E + T ED +D+ H R
Sbjct: 164 RERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRS 223
Query: 105 PFAEKDEHTGIHTMKLEHIAADIKKGLAAKREMI---KIDKAAYRKTKNTIERALKKKQL 161
P E +L +K+ +R+++ + + RKT + + +
Sbjct: 224 PPRPPRER-----FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSG 278
Query: 162 KRQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVED 221
++ + + E E+++++E EE E + + EA+ + A EV E
Sbjct: 279 SEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQS-----AEEVSEEEM 333
Query: 222 EEEEEKEEEE------EKEEEEEEGEEEGGGEEGEEG 252
E+EE+E E E + + GE E EE EG
Sbjct: 334 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEG 370
Score = 35.8 bits (81), Expect = 0.055
Identities = 34/161 (21%), Positives = 69/161 (42%), Gaps = 14/161 (8%)
Query: 134 KREMIKIDKAAYRKTKNTIERALKKKQLKR-QKRDYRHTRKLLNVLKEYIAEKQKDDEAE 192
KR + +KA ++ KN+ +R K+ L+ + RD H ++ Y E +D E
Sbjct: 21 KRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRD--HCMEITIRNSPYRREDSMEDRGE 78
Query: 193 EAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEG 252
E ++ A + + V ++E+ KE++ + +E+E E E+
Sbjct: 79 EDDSLAIKPPQQMSRKEK-------VHHRKDEKRKEKKHARVKEKEREHERRKRHREEQD 131
Query: 253 GGGGEGEETEEEEEEEEEEEEE----EQIKAFQEKQKRWQQ 289
E E + E E E EQ++ +E++++ ++
Sbjct: 132 KARREWERQKRREMAREHSRRERDRLEQLERKRERERKMRE 172
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 73.6 bits (179), Expect = 2e-13
Identities = 65/242 (26%), Positives = 109/242 (45%), Gaps = 18/242 (7%)
Query: 49 RKRSRKA---AKAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDEHGEREP 105
RKR R+ A+ + E Q R A++H+ ++ R E ER E + + E E++
Sbjct: 100 RKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKE 159
Query: 106 FAEKDEHTGIHTMKLEHIAAD---IKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLK 162
+ E ++A +++ + K + ++ R + E +K +K
Sbjct: 160 RERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVK 219
Query: 163 RQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDE 222
+K + R LL+ L++ D E + + A +++AE+ + +E E E+E
Sbjct: 220 EEKME---ERDLLSDLQDI-----SDSERKTSSAESSSAESGSGSEEEEEEEE----EEE 267
Query: 223 EEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQE 282
EE EE E+EEEEEE EEE G EE E +EEE E+EE E E + E
Sbjct: 268 EEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPE 327
Query: 283 KQ 284
+
Sbjct: 328 SR 329
Score = 52.4 bits (124), Expect = 6e-07
Identities = 58/272 (21%), Positives = 113/272 (41%), Gaps = 26/272 (9%)
Query: 29 KEGSGIASNFPGQPTMEPVGRKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDECEERNPF 88
+E +A P Q + + R + K + + +A KH E E R
Sbjct: 44 EEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRH 103
Query: 89 TETREEDVTDEHGEREPFAEKDEHTGIHTMKLEHIAADIKKGLAAKREMIKIDKAAYRKT 148
E E+D ER+ E M EH ++RE ++++ ++
Sbjct: 104 RE--EQDKARREWERQKRRE---------MAREH----------SRRERDRLEQLERKRE 142
Query: 149 KNTIERALKKKQLKRQKRDYR--HTRKLLNVLKEYIAEKQ--KDDEAEEAEAAA-AAAEA 203
+ R +K+Q ++++R+ R RK +E A + ++D +++ +A+ + +
Sbjct: 143 RERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPP 202
Query: 204 AAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEE 263
E V++E+ EE++ + ++ + + E G G EE EE
Sbjct: 203 RPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEE 262
Query: 264 EEEEEEEEEEEEQIKAFQEKQKRWQQPTGVRS 295
EEEEEEE E+ + +E+++ ++ TG S
Sbjct: 263 EEEEEEEGSTSEESEEEEEEEEEEEEETGSNS 294
Score = 39.3 bits (90), Expect = 0.005
Identities = 47/217 (21%), Positives = 87/217 (40%), Gaps = 23/217 (10%)
Query: 49 RKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDE----HGERE 104
R+R RK + Q E + + ++ + R+ E + T ED +D+ H R
Sbjct: 141 RERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRS 200
Query: 105 PFAEKDEHTGIHTMKLEHIAADIKKGLAAKREMI---KIDKAAYRKTKNTIERALKKKQL 161
P E +L +K+ +R+++ + + RKT + + +
Sbjct: 201 PPRPPRER-----FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSG 255
Query: 162 KRQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVED 221
++ + + E E+++++E EE E + + EA+ + A EV E
Sbjct: 256 SEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQS-----AEEVSEEEM 310
Query: 222 EEEEEKEEEE------EKEEEEEEGEEEGGGEEGEEG 252
E+EE+E E E + + GE E EE EG
Sbjct: 311 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEG 347
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 73.6 bits (179), Expect = 2e-13
Identities = 65/242 (26%), Positives = 109/242 (45%), Gaps = 18/242 (7%)
Query: 49 RKRSRKA---AKAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDEHGEREP 105
RKR R+ A+ + E Q R A++H+ ++ R E ER E + + E E++
Sbjct: 89 RKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKE 148
Query: 106 FAEKDEHTGIHTMKLEHIAAD---IKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLK 162
+ E ++A +++ + K + ++ R + E +K +K
Sbjct: 149 RERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVK 208
Query: 163 RQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDE 222
+K + R LL+ L++ D E + + A +++AE+ + +E E E+E
Sbjct: 209 EEKME---ERDLLSDLQDI-----SDSERKTSSAESSSAESGSGSEEEEEEEE----EEE 256
Query: 223 EEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQE 282
EE EE E+EEEEEE EEE G EE E +EEE E+EE E E + E
Sbjct: 257 EEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPE 316
Query: 283 KQ 284
+
Sbjct: 317 SR 318
Score = 60.5 bits (145), Expect = 2e-09
Identities = 67/271 (24%), Positives = 105/271 (38%), Gaps = 36/271 (13%)
Query: 36 SNFPGQPTMEPVGRKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTETREED 95
S + + +ME G + A K Q + K H KD R E + + RE +
Sbjct: 31 SPYRREDSMEDRGEEDDSLAIKPP---QQMSRKEKVHHRKDEKRKEKKHARVKEKEREHE 87
Query: 96 VTDEHGEREPFAEKD-EHTGIHTMKLEHIAA--DIKKGLAAKREMIKIDKAAYRKTKNTI 152
H E + A ++ E M EH D + L KRE + + ++ +
Sbjct: 88 RRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQK 147
Query: 153 ERALKKKQLKRQKRDYRHTRKLLNVLKEYIAEKQK------------------------- 187
ER + ++ ++++ R ++E ++K K
Sbjct: 148 ERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPV 207
Query: 188 DDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEE-----EEGEE 242
+E E + + + +E ++AE E E+EEEEE+EEEE EE EE
Sbjct: 208 KEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEE 267
Query: 243 EGGGEEGEEGGGGGEGEETEEEEEEEEEEEE 273
E EE EE G EE E+ EE EEE
Sbjct: 268 EEEEEEEEEEETGSNSEEASEQSAEEVSEEE 298
Score = 39.3 bits (90), Expect = 0.005
Identities = 47/217 (21%), Positives = 87/217 (40%), Gaps = 23/217 (10%)
Query: 49 RKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDE----HGERE 104
R+R RK + Q E + + ++ + R+ E + T ED +D+ H R
Sbjct: 130 RERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRS 189
Query: 105 PFAEKDEHTGIHTMKLEHIAADIKKGLAAKREMI---KIDKAAYRKTKNTIERALKKKQL 161
P E +L +K+ +R+++ + + RKT + + +
Sbjct: 190 PPRPPRER-----FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSG 244
Query: 162 KRQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVED 221
++ + + E E+++++E EE E + + EA+ + A EV E
Sbjct: 245 SEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQS-----AEEVSEEEM 299
Query: 222 EEEEEKEEEE------EKEEEEEEGEEEGGGEEGEEG 252
E+EE+E E E + + GE E EE EG
Sbjct: 300 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEG 336
Score = 28.9 bits (63), Expect = 6.7
Identities = 29/142 (20%), Positives = 59/142 (41%), Gaps = 14/142 (9%)
Query: 153 ERALKKKQLKR-QKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAA 211
+R K+ L+ + RD+R + N Y E +D EE ++ A + +
Sbjct: 6 DRDSKRDSLEEGELRDHRMEITIRN--SPYRREDSMEDRGEEDDSLAIKPPQQMSRKEK- 62
Query: 212 AAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEE 271
V ++E+ KE++ + +E+E E E+ E E + E E
Sbjct: 63 ------VHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKARREWERQKRREMAREHS 116
Query: 272 EEE----EQIKAFQEKQKRWQQ 289
E EQ++ +E++++ ++
Sbjct: 117 RRERDRLEQLERKRERERKMRE 138
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 73.6 bits (179), Expect = 2e-13
Identities = 65/242 (26%), Positives = 109/242 (45%), Gaps = 18/242 (7%)
Query: 49 RKRSRKA---AKAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDEHGEREP 105
RKR R+ A+ + E Q R A++H+ ++ R E ER E + + E E++
Sbjct: 134 RKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKE 193
Query: 106 FAEKDEHTGIHTMKLEHIAAD---IKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLK 162
+ E ++A +++ + K + ++ R + E +K +K
Sbjct: 194 RERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERFELGDGRKPVK 253
Query: 163 RQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDE 222
+K + R LL+ L++ D E + + A +++AE+ + +E E E+E
Sbjct: 254 EEKME---ERDLLSDLQDI-----SDSERKTSSAESSSAESGSGSEEEEEEEE----EEE 301
Query: 223 EEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQE 282
EE EE E+EEEEEE EEE G EE E +EEE E+EE E E + E
Sbjct: 302 EEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPE 361
Query: 283 KQ 284
+
Sbjct: 362 SR 363
Score = 52.4 bits (124), Expect = 6e-07
Identities = 58/272 (21%), Positives = 113/272 (41%), Gaps = 26/272 (9%)
Query: 29 KEGSGIASNFPGQPTMEPVGRKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDECEERNPF 88
+E +A P Q + + R + K + + +A KH E E R
Sbjct: 78 EEDDSLAIKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEGGKHARVKEKEREHERRKRH 137
Query: 89 TETREEDVTDEHGEREPFAEKDEHTGIHTMKLEHIAADIKKGLAAKREMIKIDKAAYRKT 148
E E+D ER+ E M EH ++RE ++++ ++
Sbjct: 138 RE--EQDKARREWERQKRRE---------MAREH----------SRRERDRLEQLERKRE 176
Query: 149 KNTIERALKKKQLKRQKRDYR--HTRKLLNVLKEYIAEKQ--KDDEAEEAEAAA-AAAEA 203
+ R +K+Q ++++R+ R RK +E A + ++D +++ +A+ + +
Sbjct: 177 RERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPP 236
Query: 204 AAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEE 263
E V++E+ EE++ + ++ + + E G G EE EE
Sbjct: 237 RPPRERFELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEE 296
Query: 264 EEEEEEEEEEEEQIKAFQEKQKRWQQPTGVRS 295
EEEEEEE E+ + +E+++ ++ TG S
Sbjct: 297 EEEEEEEGSTSEESEEEEEEEEEEEEETGSNS 328
Score = 40.8 bits (94), Expect = 0.002
Identities = 35/155 (22%), Positives = 67/155 (43%), Gaps = 24/155 (15%)
Query: 134 KREMIKIDKAAYRKTKNTIERALKKKQLKR-QKRDYRHTRKLLNVLKEYIAEKQKDDEAE 192
KR + +KA ++ KN+ +R K+ L+ + RD+R + N Y E +D E
Sbjct: 21 KRRKEQEEKAEIKRLKNSDDRDSKRDSLEEGELRDHRMEITIRN--SPYRREDSMEDRGE 78
Query: 193 EAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEG 252
E ++ A ++ ++ ++E+ ++E+ E+ EG
Sbjct: 79 EDDSLA--------------------IKPPQQMSRKEKVHHRKDEKRKEKRRHRSHSAEG 118
Query: 253 GGGGEGEETEEE-EEEEEEEEEEEQIKAFQEKQKR 286
G +E E E E + EE+++ + E+QKR
Sbjct: 119 GKHARVKEKEREHERRKRHREEQDKARREWERQKR 153
Score = 39.3 bits (90), Expect = 0.005
Identities = 47/217 (21%), Positives = 87/217 (40%), Gaps = 23/217 (10%)
Query: 49 RKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDE----HGERE 104
R+R RK + Q E + + ++ + R+ E + T ED +D+ H R
Sbjct: 175 RERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRS 234
Query: 105 PFAEKDEHTGIHTMKLEHIAADIKKGLAAKREMI---KIDKAAYRKTKNTIERALKKKQL 161
P E +L +K+ +R+++ + + RKT + + +
Sbjct: 235 PPRPPRER-----FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSG 289
Query: 162 KRQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVED 221
++ + + E E+++++E EE E + + EA+ + A EV E
Sbjct: 290 SEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQS-----AEEVSEEEM 344
Query: 222 EEEEEKEEEE------EKEEEEEEGEEEGGGEEGEEG 252
E+EE+E E E + + GE E EE EG
Sbjct: 345 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEG 381
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 71.6 bits (174), Expect = 9e-13
Identities = 69/320 (21%), Positives = 148/320 (46%), Gaps = 19/320 (5%)
Query: 2 EPVGRKRSRKAAKAQLEAQVTAAQGATKEGSGIASNFPGQPTMEPVGRKRSRKAAKAQLE 61
E G+ R ++ + E QV +G +E G GQ E G+ R ++ + E
Sbjct: 98 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ-VREQEGQVREQEGQVREQE 156
Query: 62 AQVRAAPAKKHTGKDPVRD-ECEERNPFTETREEDVTDEHGERE-PFAEKDEHTGIHT-- 117
QVR + + VR+ E + R + RE++ + GE+E E++E G
Sbjct: 157 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQE--GQMGEQEGQMGEQEEQMGEQEEQ 214
Query: 118 -MKLEHIAADIKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLKRQKRDYRHTRKLLN 176
K E + ++ + + E + + +K + +++ +++Q+++Q+ R + +
Sbjct: 215 MQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQK--QEEQMRKQEEQMREQEEQMR 272
Query: 177 -----VLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEE 231
+LK+ +Q++ E+ E E E E + E EE+ K+EE+
Sbjct: 273 EQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQ 332
Query: 232 EKEEEEEEGEE-EGGGEEGEEGGGGGEGEETEEEEEEEEEEE---EEEQIKAFQEKQKRW 287
E++E+ E+ E ++ E+ G E + +EE+ ++EE+ +EEQ++ +E+ ++
Sbjct: 333 MWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQ 392
Query: 288 QQPTGVRSWRLREMKPLLEQ 307
++ G + ++ E K + +
Sbjct: 393 EEQMGEQKEQMGEQKEQMRE 412
Score = 67.4 bits (163), Expect = 2e-11
Identities = 64/320 (20%), Positives = 147/320 (45%), Gaps = 16/320 (5%)
Query: 2 EPVGRKRSRKAAKAQLEAQVTAAQGATKEGSGIASNFPGQPTMEPVGRKRSRKAAKAQLE 61
E G+ R ++ + E QV +G +E G GQ E G+ R ++ + E
Sbjct: 56 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ-VREQEGQVREQEGQVREQE 114
Query: 62 AQVRAAPAKKHTGKDPVRD-ECEERNPFTETREED--VTDEHGE-REPFAEKDEHTGIHT 117
QVR + + VR+ E + R + RE++ V ++ G+ RE + E G
Sbjct: 115 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG--- 171
Query: 118 MKLEHIAADIKKGLAAKREMI-KIDKAAYRKTKNTIERALKKKQLKRQKRDYRHTRKLLN 176
++ +++ RE ++ + + + + +++Q+++Q+ + +
Sbjct: 172 -QVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMR 230
Query: 177 VLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEE 236
+E + E+++ + +E + + E E + ++EE+ +++E+ E+E
Sbjct: 231 KQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQM--REQEEQMLKQKEQTEQE 288
Query: 237 EEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEE--EEQIKAFQEKQKRWQQPTGVR 294
E+ GE+E E EE E + E+EE+ E+EE+ +++ + +++K++ W+Q +
Sbjct: 289 EQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKE--Q 346
Query: 295 SWRLREMKPLLEQLLKAAKD 314
W+ E E+ ++ ++
Sbjct: 347 MWKQEEQMGEQEEQMQKQEE 366
Score = 65.5 bits (158), Expect = 6e-11
Identities = 64/315 (20%), Positives = 143/315 (45%), Gaps = 19/315 (6%)
Query: 2 EPVGRKRSRKAAKAQLEAQVTAAQGATKEGSGIASNFPGQPTMEPVGRKRSRKAAKAQLE 61
E G+ R ++ + E QV +G +E G GQ E G+ R ++ + E
Sbjct: 84 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ-VREQEGQVREQEGQVREQE 142
Query: 62 AQVRAAPAKKHTGKDPVRD-ECEERNPFTETREED--VTDEHGE-REPFAEKDEHTGIHT 117
QVR + + VR+ E + R + RE++ V ++ G+ RE + E G
Sbjct: 143 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEG-QM 201
Query: 118 MKLEHIAADIKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLKRQKRDYRHTRKLLNV 177
+ E + ++ + + E + + RK + + +++Q+++Q+ + + +
Sbjct: 202 GEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGE--QEEQVQKQEEQVQKQEEQMRK 259
Query: 178 LKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEE 237
+E + E Q++ E+ E E E E + ++E+ E+EE+ ++EE+
Sbjct: 260 QEEQMRE-QEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQ 318
Query: 238 EEGEEEGGGEEGEEGGGGGE----------GEETEEEEEEEEEEEEEEQIKAFQEKQKRW 287
+EE G++ E+ E +E + E+EE+ +++EEQ++ +E+ ++
Sbjct: 319 MREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQ 378
Query: 288 QQPTGVRSWRLREMK 302
++ + ++R+ +
Sbjct: 379 EEQMRKQEEQMRKQE 393
Score = 62.4 bits (150), Expect = 5e-10
Identities = 56/308 (18%), Positives = 132/308 (42%), Gaps = 12/308 (3%)
Query: 2 EPVGRKRSRKAAKAQLEAQVTAAQGATKEGSGIASNFPGQPTMEPVGRKRSRKAAKAQLE 61
E G+ R ++ + E QV +G +E G GQ E G+ R ++ + E
Sbjct: 126 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ-VREQEGQVREQEGQVREQE 184
Query: 62 AQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDEHGEREPFAEKDEHTGIHTMKLE 121
QVR + + + ++ E+ E ++ + E +++E G +++
Sbjct: 185 GQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQ 244
Query: 122 HIAADIKKGLAAKREMIKIDKAAYRKTKNTIERALKKK-------QLKRQKRDYRHTRKL 174
++K R+ + + + + E+ LK+K Q Q+ R +
Sbjct: 245 KQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQ 304
Query: 175 LNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKE 234
+ +E + E+++ +E + + E E + ++E+ E+EE+ +K+
Sbjct: 305 MREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQ 364
Query: 235 EEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQKRWQQPTGVR 294
EE+ +EE ++ E+ +E + ++EE+ E++EQ+ +E+ + ++ G +
Sbjct: 365 EEQVRKQEEQMRKQEEQ----MRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQ 420
Query: 295 SWRLREMK 302
++R+ +
Sbjct: 421 KEQMRKQE 428
Score = 58.5 bits (140), Expect = 8e-09
Identities = 64/302 (21%), Positives = 130/302 (43%), Gaps = 22/302 (7%)
Query: 7 KRSRKAAKAQL--EAQVTAAQGATKEGSGIASNFPGQPTMEPVGRKRSRKAAKAQLEAQV 64
KR + K L E QV +G +E G GQ E G+ R ++ + E QV
Sbjct: 38 KRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQ-VREQEGQVREQEGQVREQEGQV 96
Query: 65 RAAPAKKHTGKDPVRDECEERNPFTETREEDVTDEHGE-REPFAEKDEHTGIHTMKLEHI 123
R + + VR++ E V ++ G+ RE + E G + E
Sbjct: 97 REQEGQVREQEGQVREQ-----------EGQVREQEGQVREQEGQVREQEG-QVREQEGQ 144
Query: 124 AADIKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLKRQKRDYRHTRKLLNVLKEYIA 183
+ + + + ++ + R+ + + ++ Q++ Q+ R + + +
Sbjct: 145 VREQEGQVREQEGQVREQEGQVREQEGQVRE--QEGQVREQEGQVREQEGQMGEQEGQMG 202
Query: 184 EKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEE 243
E Q++ E+ E E E E + E EE+ +K+EE+ +++EE+ ++E
Sbjct: 203 E-QEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQE 261
Query: 244 GGGEEGEEGGGGGEGEETEEEEEEEEEE---EEEEQIKAFQEKQKRWQQPTGVRSWRLRE 300
E EE E + +++E+ E+EE E+EEQ++ +E+ + ++ + ++RE
Sbjct: 262 EQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMRE 321
Query: 301 MK 302
+
Sbjct: 322 QE 323
Score = 54.3 bits (129), Expect = 1e-07
Identities = 54/267 (20%), Positives = 124/267 (46%), Gaps = 14/267 (5%)
Query: 57 KAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTETREED--VTDEHGE-REPFAEKDEHT 113
K++++ ++ K T K P+ E + R + RE++ V ++ G+ RE + E
Sbjct: 27 KSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 86
Query: 114 GIHTMKLEHIAADIKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLKRQKRDYRHTRK 173
G + E + + + + ++ + R+ + + ++ Q++ Q+ R
Sbjct: 87 G-QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVRE--QEGQVREQEGQVREQEG 143
Query: 174 LLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEK 233
+ + + E++ +E + + E E V E E + ++E +
Sbjct: 144 QVREQEGQVREQEGQVREQEGQVREQEGQVREQ-EGQVREQEGQVREQEGQMGEQEGQMG 202
Query: 234 EEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEE-EEEEE---EEEQIKAFQEKQKRWQQ 289
E+EE+ GE+E ++ EE G E + ++EE+ E+EE+ +EEQ++ +E+ ++ ++
Sbjct: 203 EQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEE 262
Query: 290 PTGVRSWRLREMKPLLEQLLKAAKDTK 316
+ ++RE + EQ+LK + T+
Sbjct: 263 QMREQEEQMREQE---EQMLKQKEQTE 286
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 70.9 bits (172), Expect = 2e-12
Identities = 68/253 (26%), Positives = 109/253 (43%), Gaps = 31/253 (12%)
Query: 49 RKRSRKA---AKAQLEAQVRAAPAKKHT----GKDPV---RDECEE-------RNPFTET 91
RKR R+ A+ + E Q R A++H+ G D V RD E+ E
Sbjct: 123 RKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRERERKMREQ 182
Query: 92 REEDVTDEHGEREPFAEKDEHTGIHTMKLEHIAADIKKGLAAKREMIKIDKAAYRKTKNT 151
++E + ER + E + H +++ + K + ++ R +
Sbjct: 183 QKEQREQKERERRAEERRKEREARREVSAHH--RTMREDYSDKVKASHWSRSPPRPPRER 240
Query: 152 IERALKKKQLKRQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAA 211
E +K +K +K + R LL+ L++ D E + + A +++AE+ + +E
Sbjct: 241 FELGDGRKPVKEEKME---ERDLLSDLQDI-----SDSERKTSSAESSSAESGSGSEEEE 292
Query: 212 AAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEE 271
E E+EEE EE E+EEEEEE EEE G EE E +EEE E+EE
Sbjct: 293 EEEE----EEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEER 348
Query: 272 EEEEQIKAFQEKQ 284
E E + E +
Sbjct: 349 ENENHLLVVPESR 361
Score = 58.2 bits (139), Expect = 1e-08
Identities = 67/280 (23%), Positives = 106/280 (37%), Gaps = 45/280 (16%)
Query: 36 SNFPGQPTMEPVGRKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTETREED 95
S + + +ME G + A K Q + K H KD R E + + RE +
Sbjct: 65 SPYRREDSMEDRGEEDDSLAIKPP---QQMSRKEKVHHRKDEKRKEKKHARVKEKEREHE 121
Query: 96 VTDEHGEREPFAEKD-EHTGIHTMKLEH-----------IAADIKKGLAAKREMIKIDKA 143
H E + A ++ E M EH + D + L KRE + +
Sbjct: 122 RRKRHREEQDKARREWERQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRERERKMRE 181
Query: 144 AYRKTKNTIERALKKKQLKRQKRDYRHTRKLLNVLKEYIAEKQK---------------- 187
++ + ER + ++ ++++ R ++E ++K K
Sbjct: 182 QQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRSPPRPPRERF 241
Query: 188 ---------DDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEE- 237
+E E + + + +E ++AE E E+EEEEE+EEEE
Sbjct: 242 ELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEE 301
Query: 238 ----EEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEE 273
EE EEE EE EE G EE E+ EE EEE
Sbjct: 302 GSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEE 341
Score = 39.3 bits (90), Expect = 0.005
Identities = 47/217 (21%), Positives = 87/217 (40%), Gaps = 23/217 (10%)
Query: 49 RKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDE----HGERE 104
R+R RK + Q E + + ++ + R+ E + T ED +D+ H R
Sbjct: 173 RERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYSDKVKASHWSRS 232
Query: 105 PFAEKDEHTGIHTMKLEHIAADIKKGLAAKREMI---KIDKAAYRKTKNTIERALKKKQL 161
P E +L +K+ +R+++ + + RKT + + +
Sbjct: 233 PPRPPRER-----FELGDGRKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSG 287
Query: 162 KRQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVED 221
++ + + E E+++++E EE E + + EA+ + A EV E
Sbjct: 288 SEEEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQS-----AEEVSEEEM 342
Query: 222 EEEEEKEEEE------EKEEEEEEGEEEGGGEEGEEG 252
E+EE+E E E + + GE E EE EG
Sbjct: 343 SEDEERENENHLLVVPESRFDRDSGESEEAEEEVGEG 379
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 70.5 bits (171), Expect = 2e-12
Identities = 74/251 (29%), Positives = 107/251 (42%), Gaps = 9/251 (3%)
Query: 26 GATKEGSGIASNFPGQPTMEPVGRKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDECEER 85
G +EGS A ++ + E + + R + E + A ++ +D E +ER
Sbjct: 657 GTCEEGSSGAEHWQDEER-EKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKER 715
Query: 86 NPFTETREEDVTDEHGEREPFAEKDEHTGIHTMKLEHIAADIKKGLAAKREMIKIDKAAY 145
+ +E GE E E +E G + E ++G + E + +
Sbjct: 716 EQGHQKERNQEMEEGGEEE-HGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGE 774
Query: 146 RKTKNTIERALKKKQLKRQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAA 205
RK + ERA K+++ + + + E EK++ E E E E
Sbjct: 775 RKKE---ERAGKEEKGEEEGDQGEGEEEETEGRGE---EKEEGGEVEGGEVEEGKGEREE 828
Query: 206 AAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEE 265
E E E EEE E EEEE + + EEEGEE G EEGEEG G GE EE E E
Sbjct: 829 EEEEGEGEEEEGEGE-EEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEG 887
Query: 266 EEEEEEEEEEQ 276
EEE E E EE+
Sbjct: 888 EEEGEGEGEEE 898
Score = 69.3 bits (168), Expect = 4e-12
Identities = 47/109 (43%), Positives = 58/109 (53%), Gaps = 6/109 (5%)
Query: 179 KEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEE 238
+E E + ++E EE E E E E E+E E E EEEE + E EE
Sbjct: 913 EEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGE----EEEGEWEGEEEEGEGEGEE 968
Query: 239 EGEEEG--GGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQK 285
EGE EG G EGEE G GEGEE E EEE EEE E EE+ + E+++
Sbjct: 969 EGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEE 1017
Score = 69.3 bits (168), Expect = 4e-12
Identities = 43/103 (41%), Positives = 52/103 (50%), Gaps = 5/103 (4%)
Query: 184 EKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEE 243
E++ + E EE E E E E +EEE E E E E EE E EGEEE
Sbjct: 983 EEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGE-----EEEEGEVEGEVEGEEGEGEGEEE 1037
Query: 244 GGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQKR 286
G EEGEE GEGEE EEEEEEE + Q +E +++
Sbjct: 1038 EGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQ 1080
Score = 68.2 bits (165), Expect = 1e-11
Identities = 45/115 (39%), Positives = 58/115 (50%), Gaps = 13/115 (11%)
Query: 184 EKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEE 243
E+++ + E E E E E E E E E+EE EE+ EEE EGEEE
Sbjct: 949 EEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEE 1008
Query: 244 GGGE-------------EGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQK 285
G GE EGEEG G GE EE EEE EE E+E E E+ + +E+++
Sbjct: 1009 GEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEE 1063
Score = 67.4 bits (163), Expect = 2e-11
Identities = 47/114 (41%), Positives = 58/114 (50%), Gaps = 5/114 (4%)
Query: 184 EKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKE---EEEEEG 240
E+ + + EE E E E E E+E EEE E EEE E EEEEEG
Sbjct: 960 EEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEG 1019
Query: 241 EEEGG--GEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQKRWQQPTG 292
E EG GEEGE G EGEE EE E+E E EE + + +E+++ Q TG
Sbjct: 1020 EVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEEGKYQETG 1073
Score = 66.2 bits (160), Expect = 4e-11
Identities = 48/110 (43%), Positives = 58/110 (52%), Gaps = 9/110 (8%)
Query: 184 EKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEE---EG 240
E++++ E EE E E E E E E EEE EE E + EEEE EG
Sbjct: 828 EEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEG 887
Query: 241 EEEGGGEEGEEGGGGGEGEETEEEEEEEEE-----EEEEEQIKAFQEKQK 285
EEEG GE GEE G GEGEE E E EEEE EEE E+ + E+++
Sbjct: 888 EEEGEGE-GEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEE 936
Score = 66.2 bits (160), Expect = 4e-11
Identities = 49/127 (38%), Positives = 63/127 (49%), Gaps = 10/127 (7%)
Query: 184 EKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEE 243
E++ + E E+ E E E E + E EE E E E+EE E EGEEE
Sbjct: 934 EEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEE 993
Query: 244 GGGEEGEEGG-----GGGEGEETEE-----EEEEEEEEEEEEQIKAFQEKQKRWQQPTGV 293
G EEGEE G G GEGEE EE E E EE E E E+ + +E ++R ++ G
Sbjct: 994 EGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGE 1053
Query: 294 RSWRLRE 300
+ R RE
Sbjct: 1054 ENRRNRE 1060
Score = 64.7 bits (156), Expect = 1e-10
Identities = 45/106 (42%), Positives = 53/106 (50%), Gaps = 11/106 (10%)
Query: 179 KEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEE 238
+E E + ++E EE E E E E E+E E E EEEE + E EE
Sbjct: 850 EEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEG---EEEGEGEGEEEEGEGEGEE 906
Query: 239 EGEEEG--------GGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQ 276
EGE EG G EEGEEG G GE EE E E E+ E E EEE+
Sbjct: 907 EGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEE 952
Score = 63.5 bits (153), Expect = 2e-10
Identities = 45/94 (47%), Positives = 49/94 (52%), Gaps = 2/94 (2%)
Query: 184 EKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVV-EDEEEEEKEEEEEKEEEEEEGEE 242
E++ + E EE E E E E ED E E +EEE E E EEEEGE
Sbjct: 905 EEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEG 964
Query: 243 EGGGE-EGEEGGGGGEGEETEEEEEEEEEEEEEE 275
EG E EGE G GEGEE E E E EEEE EEE
Sbjct: 965 EGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEE 998
Score = 62.4 bits (150), Expect = 5e-10
Identities = 70/259 (27%), Positives = 112/259 (43%), Gaps = 23/259 (8%)
Query: 26 GATKEGSGIASNFPGQPTMEPVGRKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDECEER 85
G KE + I S+ G+ +S A+ E + + +G + +DE E+
Sbjct: 617 GGRKEKTEILSDDLTDKAEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREK 676
Query: 86 NPFTETREEDVTDEHGEREPFAEKDEHTGIHTMKLEHIAADIKKGLAAKREMIKIDKAAY 145
+ R E GE+E AEK+E KK ++E + ++
Sbjct: 677 GEKDKGRGEMERPGEGEKE-LAEKEEW---------------KKRDGEEQEQKEREQGHQ 720
Query: 146 RKTKNTIERALKKKQLKRQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAA 205
++ +E +++ + ++ + + +E E +++ E EE E E
Sbjct: 721 KERNQEMEEGGEEEHGEGEEEEGDREEE-----EEKEGEGKEEGEGEEVEGEREKEEGER 775
Query: 206 AAEAAAAAAEVIVVE-DEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEE 264
E A E E D+ E E+EE E + EE+EEG E GGE EEG G E EE E E
Sbjct: 776 KKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEV-EEGKGEREEEEEEGE 834
Query: 265 EEEEEEEEEEEQIKAFQEK 283
EEEE E EEE+ + +E+
Sbjct: 835 GEEEEGEGEEEEGEGEEEE 853
Score = 62.4 bits (150), Expect = 5e-10
Identities = 43/96 (44%), Positives = 50/96 (52%), Gaps = 3/96 (3%)
Query: 184 EKQKDDEAEEAEAAAAAAEAAAAAEAAAAA-AEVIVVEDEEEEEKEEEEEKEEEEEEGEE 242
E + ++E EE E E E E E E EEE E E E+EE E +GEE
Sbjct: 864 EGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEE 923
Query: 243 EG--GGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQ 276
EG G EGEE G GEGE+ E E EEEE E E E+
Sbjct: 924 EGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEE 959
Score = 62.0 bits (149), Expect = 7e-10
Identities = 42/96 (43%), Positives = 48/96 (50%), Gaps = 5/96 (5%)
Query: 185 KQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEG 244
++++ E EE E E E E +EEE E E EEE E E EE E EG
Sbjct: 843 EEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEG 902
Query: 245 GGE-----EGEEGGGGGEGEETEEEEEEEEEEEEEE 275
GE EGEE G G+GEE EE E E EEEE E
Sbjct: 903 EGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGE 938
Score = 56.2 bits (134), Expect = 4e-08
Identities = 44/106 (41%), Positives = 52/106 (49%), Gaps = 8/106 (7%)
Query: 179 KEYIAEKQKDDEAE-EAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEE 237
+E E + ++E E E E E E E +EE EE E E E+EE E
Sbjct: 879 EEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGE 938
Query: 238 EEGEE-EGGGE------EGEEGGGGGEGEETEEEEEEEEEEEEEEQ 276
EGE+ EG GE EGEE G GEGEE E E EE E E EE+
Sbjct: 939 GEGEDGEGEGEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEE 984
Score = 55.5 bits (132), Expect = 7e-08
Identities = 40/118 (33%), Positives = 56/118 (47%), Gaps = 11/118 (9%)
Query: 179 KEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEE 238
+E E++ ++E E E E E VE EE E + EEEE EEE E
Sbjct: 991 EEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGE------VEGEEGEGEGEEEEGEEEGE 1044
Query: 239 EGEEEGGGEEG-----EEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQKRWQQPT 291
E E+EG GEE EE G+ +ET EEE E ++ EE +++ + K + T
Sbjct: 1045 EREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKT 1102
Score = 54.3 bits (129), Expect = 1e-07
Identities = 39/114 (34%), Positives = 58/114 (50%), Gaps = 6/114 (5%)
Query: 185 KQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKE---EEEEEGE 241
K++D E +E + + E E +EEE ++EEEEEKE +EE EGE
Sbjct: 703 KKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEEEKEGEGKEEGEGE 762
Query: 242 EEGGGEEGEEGGGGGE---GEETEEEEEEEEEEEEEEQIKAFQEKQKRWQQPTG 292
E G E EEG E G+E + EEE ++ E EEE+ + E+++ + G
Sbjct: 763 EVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEG 816
Score = 53.9 bits (128), Expect = 2e-07
Identities = 37/120 (30%), Positives = 61/120 (50%), Gaps = 9/120 (7%)
Query: 183 AEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEE 242
AE +D+E E+ E E E E + E EE ++++ EE++++E E+G +
Sbjct: 666 AEHWQDEEREKGEKDKGRGEMERPGEG-----EKELAEKEEWKKRDGEEQEQKEREQGHQ 720
Query: 243 EGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQKRWQQPTGVRSWRLREMK 302
+ +E EEGG EE E EEEE + EEEE+ + +++ ++ G R E K
Sbjct: 721 KERNQEMEEGGE----EEHGEGEEEEGDREEEEEKEGEGKEEGEGEEVEGEREKEEGERK 776
Score = 40.4 bits (93), Expect = 0.002
Identities = 59/262 (22%), Positives = 102/262 (38%), Gaps = 28/262 (10%)
Query: 32 SGIASNFPGQPTMEPVGRKRSRKAAKAQLEAQVRAAPAKKHTG------KDPVRDECEER 85
S + S Q T+ R+R R+ + + P + G + V C ER
Sbjct: 394 SSLTSGNVLQRTLSARMRRRERERSPDSFSMRRTLPPIEGTLGLSACFLPNSVFPRCSER 453
Query: 86 NPFTETREEDVTDEHGEREPFAEKDEHTGIHTMKLEHIAADIKKGLAAKREMIKIDKAAY 145
N +E V E +P E D T + E + + L +++ + +
Sbjct: 454 N-----LQESVLSEQDLMQP-EEPDYLLDEMTKEAEIDNSSTVESLGETTDILNM---TH 504
Query: 146 RKTKNTIERALKKKQLKRQKRDYRHTRKLLNVLKEYIAEKQKDDE------AEEAEAAAA 199
+ N+ E++LK +++QK+ ++ + L + A + DD +E E A
Sbjct: 505 IMSLNSNEKSLKLSPVQKQKK-----QQTIGELTQDTALTENDDSDEYEEMSEMKEGKAC 559
Query: 200 AAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEG--GGGGE 257
+ A + DEE E EE+E E+ + G EE E EE GG
Sbjct: 560 KQHVSQGIFMTQPATTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGR 619
Query: 258 GEETEEEEEEEEEEEEEEQIKA 279
E+TE ++ ++ E + KA
Sbjct: 620 KEKTEILSDDLTDKAEVSEGKA 641
Score = 35.4 bits (80), Expect = 0.071
Identities = 33/115 (28%), Positives = 53/115 (46%), Gaps = 14/115 (12%)
Query: 188 DDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGE 247
DD ++AE + A++ AE D EE E ++EE E
Sbjct: 628 DDLTDKAEVSEGKAKSVGEAEDGPEGRG-----DGTCEEGSSGAEHWQDEER-------E 675
Query: 248 EGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQKRWQQPTGVRSWRLREMK 302
+GE+ G GE E E E+E E+EE ++ +++QK +Q G + R +EM+
Sbjct: 676 KGEKDKGRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQ--GHQKERNQEME 728
>gi|105990539 neurofilament, light polypeptide 68kDa [Homo sapiens]
Length = 543
Score = 69.3 bits (168), Expect = 4e-12
Identities = 46/113 (40%), Positives = 63/113 (55%), Gaps = 6/113 (5%)
Query: 171 TRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEE 230
TR + ++ E+Q E EE AA A EA + A E E++++EE EEE
Sbjct: 436 TRSFPSYYTSHVQEEQI--EVEETIEAAKAEEAKDEPPSEGEAEE----EEKDKEEAEEE 489
Query: 231 EEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEK 283
E EEEE EE +E EEGG G EGEET+E EEEE++ E + +A ++K
Sbjct: 490 EAAEEEEAAKEESEEAKEEEEGGEGEEGEETKEAEEEEKKVEGAGEEQAAKKK 542
Score = 43.1 bits (100), Expect = 3e-04
Identities = 46/208 (22%), Positives = 84/208 (40%), Gaps = 33/208 (15%)
Query: 127 IKKGLAAKREMIKIDKAAYRKTKNTIERALK--KKQLKRQKRDYRHTRKLLNVLKEYIAE 184
++K L + D +A + T N +E L+ K ++ R ++Y+ + L IA
Sbjct: 329 LEKQLQELEDKQNADISAMQDTINKLENELRTTKSEMARYLKEYQDLLNVKMALDIEIAA 388
Query: 185 KQKDDEAEEAEAAAAAAEAAAAAEAAAAAA--------------------------EVIV 218
+K E EE + + + + + ++ +
Sbjct: 389 YRKLLEGEETRLSFTSVGSITSGYSQSSQVFGRSAYGGLQTSSYLMSTRSFPSYYTSHVQ 448
Query: 219 VEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIK 278
E E EE E + EE ++E EG EE E+ + EE EEEE EEEE +E+ +
Sbjct: 449 EEQIEVEETIEAAKAEEAKDEPPSEGEAEEEEK-----DKEEAEEEEAAEEEEAAKEESE 503
Query: 279 AFQEKQKRWQQPTGVRSWRLREMKPLLE 306
+E+++ + G + E + +E
Sbjct: 504 EAKEEEEGGEGEEGEETKEAEEEEKKVE 531
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 66.2 bits (160), Expect = 4e-11
Identities = 65/242 (26%), Positives = 103/242 (42%), Gaps = 48/242 (19%)
Query: 74 GKDPVRDECEERNPFT--ETREEDVTDEHGEREPFAEKDEHTGIHTMKLEHIAADIKKGL 131
G+ PV + + P +T EE+ D H F D + ++++K+G
Sbjct: 1184 GRKPVLRKAFQHQPGKKRQTEEEEGKDNHC----FKNADPCRN----NMNDDSSNLKEGS 1235
Query: 132 AAKREMIKIDKAAYRKTKNTIERALKKKQLKR--QKRDYRHTRKLLNVLKEYIAEKQKD- 188
E +K + + TK + + + K+ K + Y + ++ E+QK+
Sbjct: 1236 KDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKET 1295
Query: 189 -------------DEAEEAEAAAAAAEAAAAAEAAAAAA---------EVIVVEDEEEEE 226
+E +E A E E A + E +++ EEEEE
Sbjct: 1296 SEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEE 1355
Query: 227 KEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEE-------------EEEEEEEEEE 273
+EEEEE+EEEEEEGEEE GG E+ G + +E EE ++ EEEEEE+
Sbjct: 1356 EEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEED 1415
Query: 274 EE 275
EE
Sbjct: 1416 EE 1417
Score = 59.3 bits (142), Expect = 5e-09
Identities = 44/113 (38%), Positives = 58/113 (51%), Gaps = 23/113 (20%)
Query: 222 EEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQ 281
+E E+EEEEE EEEEEE EEE EE EEEEEEEEEEEEEE I Q
Sbjct: 1066 KESSEEEEEEEDEEEEEEEEEE---------------EEDEEEEEEEEEEEEEENI---Q 1107
Query: 282 EKQKRWQQPTGVRSWRLREMKPLLEQLLKAAKDTKDNYCIISS--SEESELDN 332
R +P V ++ +P + + + K + N + + SE +E+ N
Sbjct: 1108 SSPPRLTKPQSV---AIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLN 1157
Score = 42.7 bits (99), Expect = 4e-04
Identities = 29/103 (28%), Positives = 44/103 (42%), Gaps = 1/103 (0%)
Query: 184 EKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEE-EEEKEEEEEKEEEEEEGEE 242
E+++++E EE E E E A+ E+ E EKE+ ++ EEE EE
Sbjct: 1355 EEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEE 1414
Query: 243 EGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQK 285
+ E+ E + E E E+EE E K E Q+
Sbjct: 1415 DEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLENQE 1457
Score = 40.0 bits (92), Expect = 0.003
Identities = 29/107 (27%), Positives = 47/107 (43%), Gaps = 11/107 (10%)
Query: 194 AEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGG-------- 245
+ AA + E A EA + E EE+E + + + +
Sbjct: 993 SNAAVSEEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESR 1052
Query: 246 ---GEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQKRWQQ 289
GE G+ E E EEEEE+EEEEEEEE+ + +E+++ ++
Sbjct: 1053 PVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEE 1099
Score = 40.0 bits (92), Expect = 0.003
Identities = 24/67 (35%), Positives = 36/67 (53%), Gaps = 22/67 (32%)
Query: 173 KLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEE 232
+LL + KE E++++++ EE E E+EEE+E+EEEEE
Sbjct: 1060 QLLELSKESSEEEEEEEDEEEEEEE----------------------EEEEEDEEEEEEE 1097
Query: 233 KEEEEEE 239
+EEEEEE
Sbjct: 1098 EEEEEEE 1104
Score = 35.0 bits (79), Expect = 0.093
Identities = 23/99 (23%), Positives = 43/99 (43%), Gaps = 5/99 (5%)
Query: 187 KDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGG 246
K +E EE E E E V D + +++EE E E+E+
Sbjct: 1349 KPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDH 1408
Query: 247 EEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQK 285
EE EE E EE E+ + ++E++ +++ + +++
Sbjct: 1409 EEEEE-----EDEEPSHNEDHDADDEDDSHMESAEVEKE 1442
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 65.9 bits (159), Expect = 5e-11
Identities = 36/63 (57%), Positives = 46/63 (73%)
Query: 222 EEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQ 281
+EEEE+EEEEE+EEEEEE EEE EE E+ E EE EEEE EEE EEEE +++ +
Sbjct: 887 DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE 946
Query: 282 EKQ 284
E++
Sbjct: 947 EEE 949
Score = 64.3 bits (155), Expect = 1e-10
Identities = 37/60 (61%), Positives = 41/60 (68%)
Query: 216 VIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEE 275
VI + +EEE+EEEEE+EEEEEE EEE EE EE EE EEEEE EEE EEEE
Sbjct: 880 VININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEE 939
Score = 64.3 bits (155), Expect = 1e-10
Identities = 38/67 (56%), Positives = 46/67 (68%), Gaps = 4/67 (5%)
Query: 220 EDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETE----EEEEEEEEEEEEE 275
E+EEEEE+EEEEE EEEEE EEE EE EE E E E EEEEEEE+EEEEE
Sbjct: 896 EEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEE 955
Query: 276 QIKAFQE 282
+++ ++
Sbjct: 956 ELEEVED 962
Score = 63.5 bits (153), Expect = 2e-10
Identities = 39/68 (57%), Positives = 43/68 (63%), Gaps = 13/68 (19%)
Query: 220 EDEEEEEKEEEEEKEEEEEEG-------------EEEGGGEEGEEGGGGGEGEETEEEEE 266
E+EEEEE+EEEEE+EEEEEE EEE EE EE EGE EEEEE
Sbjct: 889 EEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEE 948
Query: 267 EEEEEEEE 274
E+EEEEEE
Sbjct: 949 EDEEEEEE 956
Score = 63.5 bits (153), Expect = 2e-10
Identities = 36/70 (51%), Positives = 48/70 (68%)
Query: 220 EDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKA 279
E+EEEEE+EEEEE+EEEEE+ EEE EE E EE EEE EEEE E EEE+ +
Sbjct: 890 EEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEE 949
Query: 280 FQEKQKRWQQ 289
+E+++ ++
Sbjct: 950 DEEEEEELEE 959
Score = 63.2 bits (152), Expect = 3e-10
Identities = 38/62 (61%), Positives = 43/62 (69%), Gaps = 3/62 (4%)
Query: 220 EDEEEEEKEEEEEKEEE---EEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQ 276
E+EEEE+ EEEEE EEE EEE EEE EE EE G E EE EE+EEEEEE EE E
Sbjct: 903 EEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVED 962
Query: 277 IK 278
++
Sbjct: 963 LE 964
Score = 59.7 bits (143), Expect = 4e-09
Identities = 34/65 (52%), Positives = 44/65 (67%)
Query: 221 DEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAF 280
+ +EE+EEEEE+EEEEEE EEE E EE EE EEEEEE EEE EEE+ +
Sbjct: 884 NSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELE 943
Query: 281 QEKQK 285
+E+++
Sbjct: 944 EEEEE 948
Score = 58.9 bits (141), Expect = 6e-09
Identities = 37/74 (50%), Positives = 47/74 (63%), Gaps = 7/74 (9%)
Query: 211 AAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEE 270
A ++ V+ +E+EEEEE+EEEEEE EEE EE E E EE EEE EEEE
Sbjct: 873 ALEEDLTVININSSDEEEEEEEEEEEEEEEEEE--EEEDFE-----EEEEDEEEYFEEEE 925
Query: 271 EEEEEQIKAFQEKQ 284
EEEEE + F+E++
Sbjct: 926 EEEEEFEEEFEEEE 939
Score = 55.5 bits (132), Expect = 7e-08
Identities = 43/103 (41%), Positives = 54/103 (52%), Gaps = 19/103 (18%)
Query: 174 LLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEE-EKEEEEE 232
++N+ E+++++E EE E E E EDEEE E+EEEEE
Sbjct: 880 VININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEE-----------EDEEEYFEEEEEEE 928
Query: 233 KEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEE 275
+E EEE EEEG EE EE EE EEEEEE EE E+ E
Sbjct: 929 EEFEEEFEEEEGELEEEEE-------EEDEEEEEELEEVEDLE 964
Score = 43.5 bits (101), Expect = 3e-04
Identities = 24/53 (45%), Positives = 31/53 (58%), Gaps = 15/53 (28%)
Query: 248 EGEEGGGG---------------GEGEETEEEEEEEEEEEEEEQIKAFQEKQK 285
EG GGGG + EE EEEEEEEEEEEEEE+ + F+E+++
Sbjct: 863 EGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEE 915
Score = 40.4 bits (93), Expect = 0.002
Identities = 27/74 (36%), Positives = 37/74 (50%), Gaps = 16/74 (21%)
Query: 179 KEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEE 238
+EY E+++++E E E E +E+EEEEE EEEEE+ EE E
Sbjct: 918 EEYFEEEEEEEEEFEEEFEEEEGE----------------LEEEEEEEDEEEEEELEEVE 961
Query: 239 EGEEEGGGEEGEEG 252
+ E G E EEG
Sbjct: 962 DLEFGTAGGEVEEG 975
Score = 34.7 bits (78), Expect = 0.12
Identities = 24/66 (36%), Positives = 34/66 (51%), Gaps = 1/66 (1%)
Query: 184 EKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEE 243
E++++DE E E E E E+ E+EE+EE+EEE E+ E+ E G
Sbjct: 911 EEEEEDEEEYFEEEEEEEEEFEE-EFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAG 969
Query: 244 GGGEEG 249
G EEG
Sbjct: 970 GEVEEG 975
Score = 33.5 bits (75), Expect = 0.27
Identities = 51/205 (24%), Positives = 79/205 (38%), Gaps = 26/205 (12%)
Query: 83 EERNPFTETREEDVTDEHGEREPFAEKDEHTGIHTMKLEHIAADIKKGLAAKREMIKIDK 142
EE E EE+ +E GE E E++E +LE + D++ G A ++++
Sbjct: 922 EEEEEEEEEFEEEFEEEEGELEE--EEEEEDEEEEEELEEVE-DLEFGTAGG----EVEE 974
Query: 143 AAYRKTKNTIERALKKKQL--KRQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAA 200
A T+ AL + K Q LL V + E++ D A A
Sbjct: 975 GA--PPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALP 1032
Query: 201 AEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEE 260
++ E + AA E EEE EEE E+G ++ +
Sbjct: 1033 SQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETEDGSDK---------------VQ 1077
Query: 261 TEEEEEEEEEEEEEEQIKAFQEKQK 285
E EEE E E + +A QEK++
Sbjct: 1078 PPPETPAEEEMETETEAEALQEKEQ 1102
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 65.5 bits (158), Expect = 6e-11
Identities = 57/209 (27%), Positives = 96/209 (45%), Gaps = 21/209 (10%)
Query: 110 DEHTGIHTMKLEHIAADIKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLKRQKRDYR 169
+E + + E I D ++G + E+I K +RK K K++ Q +
Sbjct: 2162 EEESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVE 2221
Query: 170 HTRKLLNVLKEYIAEKQKD--DEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEK 227
+E+ +E+ + DE E+ E+ ++ E E E+ EEEE
Sbjct: 2222 S--------EEHFSEEMESLLDELEKQESLSSEEEEEREEE-----------EEREEEEV 2262
Query: 228 EEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQKRW 287
EEEE+ +EEEEGEE+ +E EE + ++ EE +E+EE EE+E+I + +E +
Sbjct: 2263 REEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLS 2322
Query: 288 QQPTGVRSWRLREMKPLLEQLLKAAKDTK 316
+ S L E +++LK K K
Sbjct: 2323 DEEEEEESCSLEEEVDREKEILKKEKQFK 2351
Score = 52.8 bits (125), Expect = 4e-07
Identities = 61/241 (25%), Positives = 110/241 (45%), Gaps = 32/241 (13%)
Query: 120 LEHIAADIKKGLAAKREMIKIDKAAYRKTKN-TIERAL----------KKKQL-KRQKRD 167
L+ + D +K + +M K+ +A + K + +IE++ K+ +L K +K+
Sbjct: 2080 LQKLTRDERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKDEKKL 2139
Query: 168 YRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVE------D 221
R RKL N ++ I +++K E EE++ A +E E E V+
Sbjct: 2140 ARKQRKLANKMRRMINKEEKMTE-EESKLARKHSEVILDDEEEGGIEEEEVIPFLKRRWR 2198
Query: 222 EEEEEKEEEEEKEE-----EEEEGEEEGGGE--------EGEEGGGGGEGEETEEEEEEE 268
+ +E K ++ KE+ +E E EE E E +E E EE EEEEE E
Sbjct: 2199 KRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEERE 2258
Query: 269 EEEEEEEQIKAFQEKQKRWQQPTGVRSWRLREMKPLLEQLLKAAKDTKDNYCIISSSEES 328
EEE EE+ + +E++ +Q + ++ K ++ ++ ++ + I S EE+
Sbjct: 2259 EEEVREEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEET 2318
Query: 329 E 329
E
Sbjct: 2319 E 2319
Score = 50.8 bits (120), Expect = 2e-06
Identities = 59/223 (26%), Positives = 101/223 (45%), Gaps = 28/223 (12%)
Query: 92 REEDVTDEHGE-----REPFAEKDEHTGIHTMKLEHIAADIKKGLAAKREMIKIDKAAYR 146
+EE +T+E + E + +E GI E + +K+ ++E + DK +
Sbjct: 2156 KEEKMTEEESKLARKHSEVILDDEEEGGIEE---EEVIPFLKRRWRKRKEAKRGDKPKEK 2212
Query: 147 KTKNTIERALKKKQLKRQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAA 206
+ E ++ + + K ++ E E+++++E EE E E
Sbjct: 2213 FSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERKEE 2272
Query: 207 AEAAAAAAEVIVVEDEEEEEKEEEEEK-----EEEEEEGEEEGGGEEGEEGGGGGEGEET 261
E E VE EEEE+K++++EK +E+EE EE+ EE E E
Sbjct: 2273 EEG-----EEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEK------EEIMSEEETESL 2321
Query: 262 EEEEEEEEE---EEEEEQIKAFQEKQKRWQ-QPTGVRSWRLRE 300
+EEEEEE EEE ++ K +K+K+++ Q +S R RE
Sbjct: 2322 SDEEEEEESCSLEEEVDREKEILKKEKQFKLQEQRRKSLRGRE 2364
Score = 47.8 bits (112), Expect = 1e-05
Identities = 55/221 (24%), Positives = 94/221 (42%), Gaps = 14/221 (6%)
Query: 118 MKLEHIAADIKK-GLAAKR-EMIKIDKAAYRKTKNTIERALKKKQLKRQKRDYRHTRKLL 175
+ +E DIK+ + KR E+ K +K RK + + ++ + ++++ KL
Sbjct: 2111 LSIEQSKLDIKEWDFSEKRSELTKDEKKLARKQRKLANKM--RRMINKEEKMTEEESKLA 2168
Query: 176 NVLKEYIAEKQKDDEAEEAEAAA------AAAEAAAAAEAAAAAAEVIVVEDEEEEEKEE 229
E I + +++ EE E + A + V E E EE E
Sbjct: 2169 RKHSEVILDDEEEGGIEEEEVIPFLKRRWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSE 2228
Query: 230 EEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEE-EEEEEEEEEEQIKAFQEKQKRWQ 288
E E +E E +E EE EE E EE EEEE EEEEE +EE+ ++ +K +
Sbjct: 2229 EMESLLDELEKQESLSSEEEEERE---EEEEREEEEVREEEEERKEEEEGEEKQVEKEEE 2285
Query: 289 QPTGVRSWRLREMKPLLEQLLKAAKDTKDNYCIISSSEESE 329
+ + + +E E++ + ++ S S+E E
Sbjct: 2286 EKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEE 2326
Score = 46.6 bits (109), Expect = 3e-05
Identities = 76/366 (20%), Positives = 145/366 (39%), Gaps = 53/366 (14%)
Query: 3 PVGRKRSRKAAKAQLEAQVTAAQGATKEGSGIASNFPGQPTM-EPVGRKRSRKAAKAQLE 61
P ++++K A+ L + T Q K+G + PG TM + + +K +K + +
Sbjct: 1344 PREEEQAQKKARDMLGLEET--QVILKKGKKVIFLEPGNVTMGKEISKKEEKKTFQKSPK 1401
Query: 62 AQVRAAPAKKHTGKDPVRDECEERNPFTE------TREEDVTDEHG-----EREPFAEK- 109
+A ++ GK R+ +E +E T EE V + G ER P +
Sbjct: 1402 QGRKAVQKERKVGKIK-REMTKEERDMSEEVEEMATLEEKVVKQEGKLVMIERTPSWQDW 1460
Query: 110 ----DEHTGIH-----------------TMKLEHIAADIKKGLAAKREMIKID-KAAYRK 147
DE +H ++ E + L+ + EM++ D K + +
Sbjct: 1461 KKAWDEWKQVHGETRKSWKAWKEEWEKRLLQEEEKLHQAGEKLSPEEEMLQEDKKLKWEE 1520
Query: 148 TKNTIERALKKKQLKRQKRDYRHTRKLLNVLKEYIAEKQKDDE----AEEAEAAAAAAEA 203
K E L K ++Q +D V +E ++Q+ E +E A
Sbjct: 1521 WKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTEEQRHIQEEHKWARIHRK 1580
Query: 204 AAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGE-----EEGGGEEGEEGGGGGEG 258
A AE A E + ++EE+ +EE + +EE + + + E + G +
Sbjct: 1581 RARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQK 1640
Query: 259 EETEEEEEEEEEEEEEEQIKAFQEKQKRW------QQPTGVRSWRLREMKPLLEQLLKAA 312
EET + E+ +E E+ + ++ K+W ++ + +L E+K +L Q ++
Sbjct: 1641 EETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEEL 1700
Query: 313 KDTKDN 318
+ N
Sbjct: 1701 PQREQN 1706
Score = 38.9 bits (89), Expect = 0.006
Identities = 48/224 (21%), Positives = 93/224 (41%), Gaps = 21/224 (9%)
Query: 93 EEDVTDEHGEREPFAEKDEHTGIHTMKLEHIAADIKKGLAAKREMIKIDKAAYRKTKNTI 152
EE+VT E EK++ T + HI + K ++ +A K +
Sbjct: 1541 EEEVTLEEEVSREGEEKEQQV---TEEQRHIQEEHKWARIHRK------RARAEKKRAQE 1591
Query: 153 ERALKKKQLKRQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAA 212
ER L +++ K + + + ++ + + Y+ Q D E +AE A E A
Sbjct: 1592 ERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKL 1651
Query: 213 AAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGG---------GEEGEEGGGGGEGEETEE 263
+ E + + ++ ++ E+ EEE+ ++GG ++ EE + + +E
Sbjct: 1652 SQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQE 1711
Query: 264 EEEEEEEEEEEEQIKAFQEKQKRWQQPTGVRSWRLREMKPLLEQ 307
+E +E EE E ++ K++ Q G + E K L E+
Sbjct: 1712 KELAQELEELEWDMEELSWKEEELNQEEGK---LVEEKKKLAEE 1752
Score = 38.9 bits (89), Expect = 0.006
Identities = 69/275 (25%), Positives = 117/275 (42%), Gaps = 52/275 (18%)
Query: 83 EERNPFTETREEDVTDEHGEREPFAEKDEHTGIHTMKL--EHIAADIKKGLAAKREMI-- 138
EE + E +E+ VT+E + E+ + IH + E A ++ LA + E +
Sbjct: 1548 EEVSREGEEKEQQVTEE---QRHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQ 1604
Query: 139 ----------KIDKAAYRKTKNTIERALKKKQLKRQKRDYRHTRKLLNVLKEYIAEKQKD 188
K+ +A + T++ E A + + +++ + L+ E +A+K+K
Sbjct: 1605 EERQLAQEERKLAQAYVKITQDDREMAQAEGKFAQKEETLAQRGEKLSQEAEKLAQKRKK 1664
Query: 189 DEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEE----------EEKEEEEEKEE--- 235
A++ E A E A A + I+ + EE +EKE +E EE
Sbjct: 1665 -LAKKWEKVAREEEKLAKKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEW 1723
Query: 236 --------EEEEGEEEGGGEEG------EEGGGGGEGEETEEEEEEEEEEEE---EEQIK 278
EEE +EEG E EE + E+ EEE + +EEE +E+ K
Sbjct: 1724 DMEELSWKEEELNQEEGKLVEEKKKLAEEEEALAWQREKLSEEETKLAQEEELLIQEKEK 1783
Query: 279 AFQEKQKRWQQPTGVRSWRLREMKPLLEQLLKAAK 313
Q K+K ++ R R RE L+E+ +K A+
Sbjct: 1784 LAQHKEKMPEEEE--RLGRKREQ--LIEKKMKLAQ 1814
Score = 37.7 bits (86), Expect = 0.014
Identities = 56/259 (21%), Positives = 109/259 (42%), Gaps = 34/259 (13%)
Query: 47 VGRKRSRKAAKAQLEAQVRAAPAKKHTGKDP--VRDECEERNPFTETREEDVTDEHGERE 104
+ RKR+R K E + A +K ++ ++E + + + ++D E +
Sbjct: 1577 IHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVKITQDDREMAQAEGK 1636
Query: 105 PFAEKDEHTGIHTMKLEHIA---ADIKKGLAAKREMIKIDKAAYRK-------TKNTIER 154
FA+K+E KL A A +K LA K E + ++ K KN + +
Sbjct: 1637 -FAQKEETLAQRGEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLAKKGGKLAEVKNILAQ 1695
Query: 155 ALKKKQLKRQKRDYRHTRKLLNVLKEYIAEKQ----KDDEAEEAEAAAAAAEAAAAAEAA 210
+++ + Q D++ ++L L+E + + K++E + E + A E
Sbjct: 1696 KVEELPQREQNLDWQE-KELAQELEELEWDMEELSWKEEELNQEEGKLVEEKKKLAEEEE 1754
Query: 211 AAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEE 270
A A + + +EE + +EEE +E+E+ + E+ EEEE
Sbjct: 1755 ALAWQREKLSEEETKLAQEEELLIQEKEKLAQ--------------HKEKMPEEEERLGR 1800
Query: 271 EEEE--EQIKAFQEKQKRW 287
+ E+ E+ +K++RW
Sbjct: 1801 KREQLIEKKMKLAQKRERW 1819
Score = 34.7 bits (78), Expect = 0.12
Identities = 42/167 (25%), Positives = 71/167 (42%), Gaps = 20/167 (11%)
Query: 125 ADIKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLKRQKRDYRHTRKLLNVLKEYIAE 184
A KK LA ++E + K K + + KKQL + K K+L ++E + +
Sbjct: 1840 AQEKKNLAQEKEKLAQRKENLLYNKERLTHS--KKQLVQVKNKLGMFNKILAQVEEKLTQ 1897
Query: 185 ------KQKDDEAE------EAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEE 232
K+K+ AE + E + A + A E A E +V+ ++ E +
Sbjct: 1898 EKETVIKKKEKLAETEKKLVQVEDSLAKKQEKLAQEKMKLALEKAMVQGKKRLRGELDIA 1957
Query: 233 KEEE------EEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEE 273
KEE+ + EE+ EG+E GE ET + + + E+E
Sbjct: 1958 KEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQE 2004
Score = 30.0 bits (66), Expect = 3.0
Identities = 26/108 (24%), Positives = 52/108 (48%), Gaps = 9/108 (8%)
Query: 49 RKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDEHGEREPFAE 108
RK + + Q+E + KK K+ ++E +E+ E +EE +++E E E ++
Sbjct: 2269 RKEEEEGEEKQVEKEEEEKKKKK---KEKKKEEVQEKEEVFEEKEEIMSEE--ETESLSD 2323
Query: 109 KDEHTGIHTMKLEHIAADIKKGLAAKREMIKIDKAAYRKTKNTIERAL 156
++E +++ E D +K + K + K+ + RK+ ER L
Sbjct: 2324 EEEEEESCSLEEE---VDREKEILKKEKQFKLQEQR-RKSLRGRERVL 2367
>gi|24415404 MDN1, midasin homolog [Homo sapiens]
Length = 5596
Score = 64.7 bits (156), Expect = 1e-10
Identities = 57/248 (22%), Positives = 99/248 (39%), Gaps = 26/248 (10%)
Query: 48 GRKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDEHGEREPFA 107
G K+ + + E + A G+D + ++ +ER + E +V HG +E
Sbjct: 4819 GNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDER----DYDENEVDPYHGNQEKVP 4874
Query: 108 EKDEHTGIHTMKLEHIAADIKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLKRQKRD 167
E + A D+ L E DK T N ++K + +
Sbjct: 4875 EPE-------------ALDLPDDLNLDSE----DKNGGEDTDNEEGEEENPLEIKEKPEE 4917
Query: 168 YRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEK 227
H + + E Q E EE + AE + A + + EE +
Sbjct: 4918 AGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSE 4977
Query: 228 EEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQKRW 287
E+++ EE+++E +EEGG E G +G + +EEEE E+ + EE+ +A + K+
Sbjct: 4978 EQQQSVEEKDKEADEEGG-----ENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHAS 5032
Query: 288 QQPTGVRS 295
TGV +
Sbjct: 5033 CGQTGVEN 5040
Score = 45.4 bits (106), Expect = 7e-05
Identities = 26/95 (27%), Positives = 49/95 (51%), Gaps = 1/95 (1%)
Query: 182 IAEKQKDDEAEEAEAAAAAAEAAAA-AEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEG 240
+ E+++DDE ++E E A E + +D+EEE++EEE+ K EE G
Sbjct: 4742 LEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPG 4801
Query: 241 EEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEE 275
+E E + G +++ +++++EE+EE
Sbjct: 4802 MDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEE 4836
Score = 41.2 bits (95), Expect = 0.001
Identities = 22/57 (38%), Positives = 33/57 (57%), Gaps = 10/57 (17%)
Query: 229 EEEEKEEEEEEGEEEGGGEEGEEGGGGGE----------GEETEEEEEEEEEEEEEE 275
E EE+EE++E+ + EGG + G GE G++ EEE+EEEE+ + EE
Sbjct: 4741 ELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEE 4797
Score = 37.7 bits (86), Expect = 0.014
Identities = 17/56 (30%), Positives = 32/56 (57%)
Query: 220 EDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEE 275
EDEEEE+ + EE +EE E ++ + G + + ++++EE+EE E ++
Sbjct: 4786 EDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADD 4841
Score = 36.6 bits (83), Expect = 0.032
Identities = 22/100 (22%), Positives = 45/100 (45%), Gaps = 9/100 (9%)
Query: 184 EKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEE 243
+ +++DE EE ++ A + + ++K ++++KEE+EE ++
Sbjct: 4782 DDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEADD 4841
Query: 244 GGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEK 283
GG GE + E+ +E + +E E + QEK
Sbjct: 4842 ---------GGQGEDKINEQIDERDYDENEVDPYHGNQEK 4872
Score = 35.4 bits (80), Expect = 0.071
Identities = 30/124 (24%), Positives = 56/124 (45%), Gaps = 18/124 (14%)
Query: 168 YRHTRKLLNVLKEYIAEKQKDD-----EAEEAEAAAAAAE-------AAAAAEAAAAAAE 215
+R T KLL+VL + E + E E A A E E ++
Sbjct: 4632 HRSTAKLLSVLAQVFTELAQKGFCLPKEFMEDSAGEGATEFHDYEGGGIGEGEGMKDVSD 4691
Query: 216 VIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEG------EEGGGGGEGEETEEEEEEEE 269
I E++ E+ ++ +EK++E+ + + + GE+ + G +GE E+EE++E+
Sbjct: 4692 QIGNEEQVEDTFQKGQEKDKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEK 4751
Query: 270 EEEE 273
+ E
Sbjct: 4752 SDSE 4755
Score = 34.3 bits (77), Expect = 0.16
Identities = 25/96 (26%), Positives = 41/96 (42%), Gaps = 6/96 (6%)
Query: 179 KEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEE 238
+E+ E+Q+ E ++ EA E A + E+EE E+ + EE+ E E
Sbjct: 4973 EEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQ------EEEEREDSDTEEQVPEALE 5026
Query: 239 EGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEE 274
E G+ G E + E E+E+ +EE
Sbjct: 5027 RKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEE 5062
Score = 31.2 bits (69), Expect = 1.3
Identities = 18/71 (25%), Positives = 39/71 (54%), Gaps = 14/71 (19%)
Query: 223 EEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETE--------------EEEEEE 268
EE +K +E +++EE +EE + EE G G + E++E +++ ++
Sbjct: 4769 EEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQ 4828
Query: 269 EEEEEEEQIKA 279
+++EE+E+ +A
Sbjct: 4829 DKKEEKEEAEA 4839
Score = 30.0 bits (66), Expect = 3.0
Identities = 20/54 (37%), Positives = 30/54 (55%), Gaps = 2/54 (3%)
Query: 234 EEEEEEGEEEGGGEEGE-EGGGGGEGEETEEEEEE-EEEEEEEEQIKAFQEKQK 285
+E E+ EG E + EGGG GEGE ++ ++ EE+ E+ + QEK K
Sbjct: 4658 KEFMEDSAGEGATEFHDYEGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDK 4711
Score = 28.5 bits (62), Expect = 8.7
Identities = 27/110 (24%), Positives = 50/110 (45%), Gaps = 3/110 (2%)
Query: 185 KQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEK--EEEEEEGEE 242
KQ D + A+ E +A+ + E +ED + +E+EE K + E+ + EE
Sbjct: 5152 KQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEE 5211
Query: 243 EGGGEEGEEGGGGGEGE-ETEEEEEEEEEEEEEEQIKAFQEKQKRWQQPT 291
G G E E +T + EE+++ ++ + EK +R ++ T
Sbjct: 5212 IKSGTTAPLGFDEMEVEIQTVKTEEDQDPRTDKAHKETENEKPERSREST 5261
>gi|169210053 PREDICTED: hypothetical protein [Homo sapiens]
Length = 185
Score = 63.9 bits (154), Expect = 2e-10
Identities = 37/80 (46%), Positives = 52/80 (65%), Gaps = 5/80 (6%)
Query: 199 AAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEG 258
+ A AA +A + + VE+EE EE+EEE E+EE+EEE EE+ EE EE E
Sbjct: 98 SVARTAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEE-----EK 152
Query: 259 EETEEEEEEEEEEEEEEQIK 278
EE EEEEE+E ++ EEE+++
Sbjct: 153 EEDEEEEEKEGKKMEEEKVE 172
Score = 63.2 bits (152), Expect = 3e-10
Identities = 42/88 (47%), Positives = 52/88 (59%), Gaps = 17/88 (19%)
Query: 198 AAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEE--EEEKEEEEEEGEEEGGGEEGEEGGGG 255
+ A AA AE +A + V E+E EEE+EE EEEKEEE+EE EEE
Sbjct: 98 SVARTAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEE------------ 145
Query: 256 GEGEETEEEEEEEEEEEEEEQIKAFQEK 283
EE EEE+EE+EEEEE+E K +EK
Sbjct: 146 ---EEKEEEKEEDEEEEEKEGKKMEEEK 170
Score = 62.4 bits (150), Expect = 5e-10
Identities = 38/88 (43%), Positives = 53/88 (60%), Gaps = 4/88 (4%)
Query: 194 AEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGG 253
A AA AE +A + E + E+EE EE+E+EEEKEE+EEE E+E EE EE
Sbjct: 100 ARTAALVAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEE-- 157
Query: 254 GGGEGEETEEEEEEEEEEEEEEQIKAFQ 281
E +E ++ EEE+ EEE + +I+ Q
Sbjct: 158 --EEEKEGKKMEEEKVEEEIDTEIQRTQ 183
Score = 41.6 bits (96), Expect = 0.001
Identities = 29/94 (30%), Positives = 44/94 (46%), Gaps = 22/94 (23%)
Query: 199 AAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEG 258
+A + A AA AE + E+EE EE+EEE EE
Sbjct: 92 SAGNRLSVARTAALVAEECSAQQGLPVEEEEVEEEEEEVEE------------------- 132
Query: 259 EETEEEEEEEEEEEEEEQIKAFQEKQKRWQQPTG 292
EE+EEE+EE+EEEE+ + +E+ + ++ G
Sbjct: 133 ---EEKEEEKEEDEEEEEKEEEKEEDEEEEEKEG 163
Score = 39.3 bits (90), Expect = 0.005
Identities = 21/60 (35%), Positives = 37/60 (61%)
Query: 257 EGEETEEEEEEEEEEEEEEQIKAFQEKQKRWQQPTGVRSWRLREMKPLLEQLLKAAKDTK 316
E EE EEEEEE EEEE+EE+ + +E++++ ++ +E K + E+ ++ DT+
Sbjct: 119 EEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKKMEEEKVEEEIDTE 178
Score = 34.7 bits (78), Expect = 0.12
Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 2/69 (2%)
Query: 177 VLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEE--KE 234
V +E A++ E EE E E E E E+E+EE++EEEE+ K+
Sbjct: 106 VAEECSAQQGLPVEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEKEEDEEEEEKEGKK 165
Query: 235 EEEEEGEEE 243
EEE+ EEE
Sbjct: 166 MEEEKVEEE 174
Score = 33.9 bits (76), Expect = 0.21
Identities = 25/63 (39%), Positives = 31/63 (49%), Gaps = 5/63 (7%)
Query: 182 IAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKE---EEEEKEEEEE 238
+ E++ ++E EE E E E E EDEEEEEKE EEEK EEE
Sbjct: 118 VEEEEVEEEEEEVEEEEKEEEKEEDEEEEEKEEEK--EEDEEEEEKEGKKMEEEKVEEEI 175
Query: 239 EGE 241
+ E
Sbjct: 176 DTE 178
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 63.2 bits (152), Expect = 3e-10
Identities = 73/316 (23%), Positives = 133/316 (42%), Gaps = 31/316 (9%)
Query: 8 RSRKAAKAQLEAQVTAAQGATKEGSGIASNFPGQPTMEPVGRKRSRKAAKAQLEAQVRAA 67
+S+K AK ++E GS +F P ++S K E + +
Sbjct: 122 KSKKTAKPKVEMY---------SGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSK 172
Query: 68 PAKKHTGKDPVRDECEERNPFTETREEDVTDEHGEREPFAEKDEHTGIHTMKLEHIAADI 127
K+ + + + +E + F ++R+ ++ + P E + K++ +A
Sbjct: 173 KIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQ-- 230
Query: 128 KKGLAAKREMIKID--KAAYRKTKNTIERALKKKQLKRQKRDYRHTRKLLNVLKEYIAEK 185
KK +RE K D KA RK K E KK +QK R ++ E
Sbjct: 231 KKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQR----------KFEEET 280
Query: 186 QKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGG 245
K + A+ E A AA E + +++++K E+EEKE+E+++G +
Sbjct: 281 VKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKAT 340
Query: 246 GEEGEEGGGGGEGEETEEEEEEEE--------EEEEEEQIKAFQEKQKRWQQPTGVRSWR 297
+ +E + EE ++ EEEE E + +E+ + QEK++R +Q R R
Sbjct: 341 VKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKER 400
Query: 298 LREMKPLLEQLLKAAK 313
L++ LL + + A+
Sbjct: 401 LKKEGKLLTKSQREAR 416
Score = 62.0 bits (149), Expect = 7e-10
Identities = 61/248 (24%), Positives = 108/248 (43%), Gaps = 26/248 (10%)
Query: 49 RKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTET---REEDVTDEHGEREP 105
+++ + +KA ++A A K + R+E E E R+E+ E +RE
Sbjct: 330 KEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRER 389
Query: 106 FAEKDEHTGIHTMKLEHIAADIKKGLAAKREM---------IKIDKAAYRKTKNTIERAL 156
+K++ K + ++ A+ E +++ K I
Sbjct: 390 KKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDK 449
Query: 157 KKKQLKRQKRDYRHTRKL-----LNVLKEYIAEKQKD------DEAEEAEAAAAAAEAAA 205
K+K++ +Q + + + V+++ + EK++ +E E+ E A A
Sbjct: 450 KRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAM 509
Query: 206 AAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEE 265
A++ E V E +E EEEEE+EEEEEE EE EE EE G EG E +EE+
Sbjct: 510 ASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEE---SEEEEEEEGESEGSEGDEED 566
Query: 266 EEEEEEEE 273
E+ +E++
Sbjct: 567 EKVSDEKD 574
Score = 54.7 bits (130), Expect = 1e-07
Identities = 82/372 (22%), Positives = 144/372 (38%), Gaps = 63/372 (16%)
Query: 6 RKRSRKAAKAQLEAQVTAAQGATKEGSGIASNFPGQPTMEPVGRKRSRKAAKAQLEAQVR 65
+K +K + + + A KE + + Q + RK + K+++
Sbjct: 231 KKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTG 290
Query: 66 AAPAKKHTGKDPVRDECEERNPFTETREEDVTDEHGEREPFAEKDEHTGIH--TMK-LEH 122
PA + + P E + + +++D + GE+E EK++ G T+K ++
Sbjct: 291 VIPASEEKAETPTAAEDDNEG---DKKKKDKKKKKGEKEE-KEKEKKKGPSKATVKAMQE 346
Query: 123 IAADIKKG-----------------LAAKR---EMIKIDKAAYRKTKNTIERALKKKQLK 162
A +K+ L AKR E ++ +K +K K + KK+ K
Sbjct: 347 ALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGK 406
Query: 163 RQKRDYRHTR-------KLLNVL------KEYIAEKQKDDEAEEAEAAAAAAEAAAAAEA 209
+ R R KLL K+ + +K+ E ++ + E+ +E+
Sbjct: 407 LLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKKIPQQLESKEVSES 466
Query: 210 AAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGG---------GEEGEEGGGGG---- 256
A V V+E E++E E EEEE E+ G EE E+ G
Sbjct: 467 MELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAMASDEETEKVEGNKVHIE 526
Query: 257 ----------EGEETEEEEEEEEEEEEEEQIKAFQEKQKRWQQPTGVRSWRLREMKPLLE 306
E EE EE+EE EEEEEEE + + + ++ + S + + KP E
Sbjct: 527 VKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKE 586
Query: 307 QLLKAAKDTKDN 318
+ D+ D+
Sbjct: 587 MSSDSEYDSDDD 598
Score = 34.3 bits (77), Expect = 0.16
Identities = 63/336 (18%), Positives = 129/336 (38%), Gaps = 46/336 (13%)
Query: 4 VGRKRSRKAAKAQLEAQVTAAQGATKEGSGIASNFPGQPTMEPVGRKRSRKAAKAQLEAQ 63
+G+K+ K+ + + A A EG+G A Q + G+K+ K
Sbjct: 1 MGKKQKNKSEDSTKDDIDLDALAAEIEGAGAAKE---QEPQKSKGKKKKEKK-------- 49
Query: 64 VRAAPAKKHTGKDPVRDECEERNPFTETREED-----VTDEHGEREPFAEKDEHTGIHTM 118
K+ +D + E EE + + + D V E F KD+
Sbjct: 50 ------KQDFDEDDILKELEELSLEAQGIKADRETVAVKPTENNEEEFTSKDKK------ 97
Query: 119 KLEHIAADIKKGLAAKREMIKIDKAAYRKTKNTIER--ALKKKQLKRQKRDYRHTRKLLN 176
KKG K++ + + + K++ + A K ++ D KL
Sbjct: 98 ---------KKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPK 148
Query: 177 VLKEYIAEKQKD-DEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEE 235
K + K D +EE E + + + ++ + + E +E + + ++K +
Sbjct: 149 KAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGD----ESDEFLQSRKGQKKNQ 204
Query: 236 EEEEGEEEGGGEEGEEGGGGGE--GEETEEEEEEEEEEEEEEQIKAFQEKQKRWQQPTGV 293
+ + G G E ++ + ++ E++E E ++ +EE+ K + K+K +
Sbjct: 205 KNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKK 264
Query: 294 RSWRLREMKPLLEQLLKAAKDTKDNYCIISSSEESE 329
+ +E + E+ +K T D I +S E++E
Sbjct: 265 DQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAE 300
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 63.2 bits (152), Expect = 3e-10
Identities = 49/167 (29%), Positives = 76/167 (45%), Gaps = 9/167 (5%)
Query: 121 EHIAADIKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQ--LKRQKRDYRHTRKLLNVL 178
E+ ++ K L A R++ A+ KN E+ +K+ +R K + + +
Sbjct: 99 EYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLE 158
Query: 179 KEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEE 238
+ A + EE + ++ + ++ E E EEE +E+ EE
Sbjct: 159 VDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSD-------EQGNNTENEEEGVEEDVEE 211
Query: 239 EGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQK 285
+ E E EE EE GE EE EEEEEEEEEEEEEE+ + + QK
Sbjct: 212 DEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQK 258
Score = 50.4 bits (119), Expect = 2e-06
Identities = 46/184 (25%), Positives = 77/184 (41%), Gaps = 11/184 (5%)
Query: 84 ERNPFTETREEDVTDEHGEREPFAEKDEHTGIHTMKLEHIAADIKKGLAAKREMIKIDKA 143
ERN + + REP+ + E T + E A ++R +++D+
Sbjct: 104 ERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPD-GSERIGLEVDRR 162
Query: 144 AYRKTKNTIERALKKKQLKRQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEA 203
A R ++++ K+++ ++ H E + ++E E + E
Sbjct: 163 ASRSSQSS------KEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVE----ED 212
Query: 204 AAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEE 263
E A EV +EEEEE+EEEEE+EEEEEE E+ ++ EEG E +
Sbjct: 213 EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASD 272
Query: 264 EEEE 267
E
Sbjct: 273 SGSE 276
Score = 36.6 bits (83), Expect = 0.032
Identities = 32/122 (26%), Positives = 54/122 (44%), Gaps = 7/122 (5%)
Query: 214 AEVIVVEDEEEEEKEEEEEKEE--EEEEGEEEGGGEEG--EEGGGGGEGEET---EEEEE 266
+E I +E + + + KEE EE G + G G +E G E EE E+ EE
Sbjct: 152 SERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEE 211
Query: 267 EEEEEEEEEQIKAFQEKQKRWQQPTGVRSWRLREMKPLLEQLLKAAKDTKDNYCIISSSE 326
+EE EE+ E+ + E + ++ E + EQ + K+ ++Y S +
Sbjct: 212 DEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEAS 271
Query: 327 ES 328
+S
Sbjct: 272 DS 273
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 63.2 bits (152), Expect = 3e-10
Identities = 49/167 (29%), Positives = 76/167 (45%), Gaps = 9/167 (5%)
Query: 121 EHIAADIKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQ--LKRQKRDYRHTRKLLNVL 178
E+ ++ K L A R++ A+ KN E+ +K+ +R K + + +
Sbjct: 99 EYQRSERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLE 158
Query: 179 KEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEE 238
+ A + EE + ++ + ++ E E EEE +E+ EE
Sbjct: 159 VDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSD-------EQGNNTENEEEGVEEDVEE 211
Query: 239 EGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQK 285
+ E E EE EE GE EE EEEEEEEEEEEEEE+ + + QK
Sbjct: 212 DEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQK 258
Score = 50.4 bits (119), Expect = 2e-06
Identities = 46/184 (25%), Positives = 77/184 (41%), Gaps = 11/184 (5%)
Query: 84 ERNPFTETREEDVTDEHGEREPFAEKDEHTGIHTMKLEHIAADIKKGLAAKREMIKIDKA 143
ERN + + REP+ + E T + E A ++R +++D+
Sbjct: 104 ERNKRLDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPD-GSERIGLEVDRR 162
Query: 144 AYRKTKNTIERALKKKQLKRQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEA 203
A R ++++ K+++ ++ H E + ++E E + E
Sbjct: 163 ASRSSQSS------KEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVE----ED 212
Query: 204 AAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEE 263
E A EV +EEEEE+EEEEE+EEEEEE E+ ++ EEG E +
Sbjct: 213 EEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEASD 272
Query: 264 EEEE 267
E
Sbjct: 273 SGSE 276
Score = 36.6 bits (83), Expect = 0.032
Identities = 32/122 (26%), Positives = 54/122 (44%), Gaps = 7/122 (5%)
Query: 214 AEVIVVEDEEEEEKEEEEEKEE--EEEEGEEEGGGEEG--EEGGGGGEGEET---EEEEE 266
+E I +E + + + KEE EE G + G G +E G E EE E+ EE
Sbjct: 152 SERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVEE 211
Query: 267 EEEEEEEEEQIKAFQEKQKRWQQPTGVRSWRLREMKPLLEQLLKAAKDTKDNYCIISSSE 326
+EE EE+ E+ + E + ++ E + EQ + K+ ++Y S +
Sbjct: 212 DEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDYDTRSEAS 271
Query: 327 ES 328
+S
Sbjct: 272 DS 273
>gi|157738619 smoothelin-like 1 [Homo sapiens]
Length = 512
Score = 62.4 bits (150), Expect = 5e-10
Identities = 66/266 (24%), Positives = 107/266 (40%), Gaps = 19/266 (7%)
Query: 28 TKEGSGIASNFPGQPTMEPVGRKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDECEERNP 87
TK +G A N G PT S K KA E + A + G D V+ E +
Sbjct: 52 TKGTAGKAIN-EGPPT-------ESGKQEKAPAEDGMSAELQGEANGLDEVKVESQREAG 103
Query: 88 FTETREEDVTDEHGEREPFAEKDEHTGIHTMKLEHIAADIKKGLAAKREMIKIDKAAYRK 147
E E ++ E GE+E + T + E ++ K+ K + +K +
Sbjct: 104 GKEDAEAELKKEDGEKEETTVGSQEM---TGRKEETKSEPKEA-EEKESTLASEKQKAEE 159
Query: 148 TKNTIERALKKKQLKRQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAA 207
+ E K R K + + T ++E A+ +E + + + + A
Sbjct: 160 KEAKPESGQKADANDRDKPEPKAT------VEEEDAKTASQEETGQRKECSTEPKEKATD 213
Query: 208 EAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEE 267
E A A ++ VVEDE + E +E + KEE + +EE +E E E EE+E+
Sbjct: 214 EEAKAESQKAVVEDEAKAEPKEPDGKEEAKHGAKEEADAKEEAEDAEEAEPGSPSEEQEQ 273
Query: 268 EEEEEEEEQIKAFQEKQKRW-QQPTG 292
+ E+E E + W + PTG
Sbjct: 274 DVEKEPEGGAGVIPSSPEEWPESPTG 299
Score = 37.4 bits (85), Expect = 0.019
Identities = 47/270 (17%), Positives = 99/270 (36%), Gaps = 17/270 (6%)
Query: 43 TMEPVGRKRSRKAAKAQLEAQVRAAPAKKHTGKDPVRDECEERNPFTETREEDVTDEHGE 102
+ E GRK K+ + E + ++K + EE+ E+ ++ ++ +
Sbjct: 126 SQEMTGRKEETKSEPKEAEEKESTLASEKQ--------KAEEKEAKPESGQKADANDRDK 177
Query: 103 REPFAEKDEHTGIHTMKLEHIAADIKKGLAAKREMIKIDKAAYRKTKNTIERALKKKQLK 162
EP A +E A+ + G + +KA + K ++A+ + + K
Sbjct: 178 PEPKATVEEEDA-------KTASQEETGQRKECSTEPKEKATDEEAKAESQKAVVEDEAK 230
Query: 163 RQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDE 222
+ ++ + + KE K++ ++AEEAE + + E E ++
Sbjct: 231 AEPKEPDGKEEAKHGAKEEADAKEEAEDAEEAEPGSPSEEQEQDVEKEPEGGAGVIPSSP 290
Query: 223 EEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQE 282
EE + E +G G+ E ++ + E E K +
Sbjct: 291 EEWPESPTGEGHNLSTDGLGPDCVASGQTSPSASESSPSDVPQSPPESPSSGE--KKEKA 348
Query: 283 KQKRWQQPTGVRSWRLREMKPLLEQLLKAA 312
++R P R R + K ++++ AA
Sbjct: 349 PERRVSAPARPRGPRAQNRKAIVDKFGGAA 378
Score = 33.5 bits (75), Expect = 0.27
Identities = 26/99 (26%), Positives = 40/99 (40%)
Query: 191 AEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGE 250
A+ E + A A A A + ++EK E+ E +GE G E
Sbjct: 37 ADNPEMSGGGAPAEETKGTAGKAINEGPPTESGKQEKAPAEDGMSAELQGEANGLDEVKV 96
Query: 251 EGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQKRWQQ 289
E G+E E E ++E+ E+EE QE R ++
Sbjct: 97 ESQREAGGKEDAEAELKKEDGEKEETTVGSQEMTGRKEE 135
>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
3 [Homo sapiens]
Length = 526
Score = 62.0 bits (149), Expect = 7e-10
Identities = 36/97 (37%), Positives = 50/97 (51%), Gaps = 4/97 (4%)
Query: 188 DDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGE 247
D E + + A +++AE+ + +E E E+EEE EE E+EEEEEE EEE G
Sbjct: 15 DSERKTSSAESSSAESGSGSEEEEEEEE----EEEEEGSTSEESEEEEEEEEEEEEETGS 70
Query: 248 EGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQ 284
EE E +EEE E+EE E E + E +
Sbjct: 71 NSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESR 107
Score = 45.8 bits (107), Expect = 5e-05
Identities = 28/70 (40%), Positives = 34/70 (48%), Gaps = 15/70 (21%)
Query: 220 EDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKA 279
E E EE+EEEEEE EEEG T EE EEEEEEEEEE+ +
Sbjct: 24 ESSSAESGSGSEEEEEEEEEEEEEGS---------------TSEESEEEEEEEEEEEEET 68
Query: 280 FQEKQKRWQQ 289
++ +Q
Sbjct: 69 GSNSEEASEQ 78
Score = 42.4 bits (98), Expect = 6e-04
Identities = 21/71 (29%), Positives = 36/71 (50%)
Query: 225 EEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQ 284
EE++ + ++ + + E G G EE EEEEEEEEE E+ + +E++
Sbjct: 2 EERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEE 61
Query: 285 KRWQQPTGVRS 295
+ ++ TG S
Sbjct: 62 EEEEEETGSNS 72
Score = 38.9 bits (89), Expect = 0.006
Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 4/66 (6%)
Query: 223 EEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEE----EEEEEEEQIK 278
EE + + + + E E G G E EE EEEEEEE EE EEEE+ +
Sbjct: 2 EERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEEE 61
Query: 279 AFQEKQ 284
+E++
Sbjct: 62 EEEEEE 67
Score = 37.7 bits (86), Expect = 0.014
Identities = 25/66 (37%), Positives = 31/66 (46%), Gaps = 14/66 (21%)
Query: 218 VVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEE-------EEEE 270
++ D ++ E + E E G EE EE EE EEEEE EEEE
Sbjct: 6 LLSDLQDISDSERKTSSAESSSAESGSGSEEEEE-------EEEEEEEEGSTSEESEEEE 58
Query: 271 EEEEEQ 276
EEEEE+
Sbjct: 59 EEEEEE 64
Score = 37.0 bits (84), Expect = 0.024
Identities = 34/127 (26%), Positives = 49/127 (38%), Gaps = 18/127 (14%)
Query: 156 LKKKQLKRQKRDYRHTRKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAE 215
++++ L +D + + + + AE E EE E E + + E+ E
Sbjct: 1 MEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEEEEEEEGSTSEESEEEEEE 60
Query: 216 VIVVEDEEEEEKEEEEEKEEE--EEEGEEEGGGEEGEEGGG-------------GGEGEE 260
E+EEEE EE E+ EE EEE +E E GE EE
Sbjct: 61 E---EEEEEETGSNSEEASEQSAEEVSEEEMSEDEERENENHLLVVPESRFDRDSGESEE 117
Query: 261 TEEEEEE 267
EEE E
Sbjct: 118 AEEEVGE 124
Score = 34.7 bits (78), Expect = 0.12
Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 8/75 (10%)
Query: 184 EKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEE------EKEEEE 237
E ++++E EE E + + A+E +A EV E E+EE+E E E +
Sbjct: 53 ESEEEEEEEEEEEEETGSNSEEASEQSAE--EVSEEEMSEDEERENENHLLVVPESRFDR 110
Query: 238 EEGEEEGGGEEGEEG 252
+ GE E EE EG
Sbjct: 111 DSGESEEAEEEVGEG 125
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 61.6 bits (148), Expect = 9e-10
Identities = 39/113 (34%), Positives = 63/113 (55%), Gaps = 7/113 (6%)
Query: 179 KEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEE--E 236
K +KQ + A + + A A++++ E + + E EE+E +E E+ +E +
Sbjct: 60 KRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKEEDEGEEYSEDNDEPGD 119
Query: 237 EEEGEEEGGGEEGEE-----GGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQ 284
E+E +EEG EE EE +GE+ E+EEEEEEEEEEEE+ + ++ Q
Sbjct: 120 EDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQ 172
Score = 60.1 bits (144), Expect = 3e-09
Identities = 31/58 (53%), Positives = 42/58 (72%), Gaps = 4/58 (6%)
Query: 220 EDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQI 277
EDEE+EE + EEE+E EEE+ +++ GE+ E+ E EE EEEEEEEEEE E+ Q+
Sbjct: 120 EDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDE----EEEEEEEEEEEEEEENEDHQM 173
Score = 56.6 bits (135), Expect = 3e-08
Identities = 37/117 (31%), Positives = 63/117 (53%), Gaps = 10/117 (8%)
Query: 182 IAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEEGE 241
+A+K+K + + E A A A++++ E + E+ +++EE+E EE E+ +
Sbjct: 57 LAKKRKTQDKQPQEPAPKRKPFAVKADSSSVD-ECDDSDGTEDMDEKEEDEGEEYSEDND 115
Query: 242 EEGGGEEGEEGGGGGEGEETEEEEE---------EEEEEEEEEQIKAFQEKQKRWQQ 289
E G +E +E G E EE EEE+E E+EEEEEEE+ + +E++ Q
Sbjct: 116 EPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENEDHQ 172
Score = 43.1 bits (100), Expect = 3e-04
Identities = 28/106 (26%), Positives = 50/106 (47%), Gaps = 16/106 (15%)
Query: 180 EYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEEEKEEEEEE 239
E + EK++D+ E +E + E E + E++E+++++ E+ ++EEEEE
Sbjct: 97 EDMDEKEEDEGEEYSEDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEE 156
Query: 240 GEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQK 285
EE EE EEEEE E+ + + Q+ +K
Sbjct: 157 EEE----------------EEEEEEEENEDHQMNCHNTRIMQDTEK 186
>gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo
sapiens]
Length = 631
Score = 61.2 bits (147), Expect = 1e-09
Identities = 34/52 (65%), Positives = 38/52 (73%), Gaps = 8/52 (15%)
Query: 228 EEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKA 279
EEE E+EEE+EE +EEGG EE EE E EEEEEEEEEEEEEEQ +A
Sbjct: 108 EEETEREEEDEEIQEEGGEEEEEE--------EEEEEEEEEEEEEEEEQPRA 151
Score = 56.2 bits (134), Expect = 4e-08
Identities = 35/84 (41%), Positives = 45/84 (53%), Gaps = 3/84 (3%)
Query: 215 EVIVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEE 274
E I E EEEE+EEEEE+EEEEEE EEE G +G GG + + EE++ EE
Sbjct: 118 EEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAGPQGSGGNHEQYSLEEDQALEEWVSS 177
Query: 275 EQIKAFQEKQKRWQQPTGVRSWRL 298
E + RWQ T + +L
Sbjct: 178 ETSAL---PRPRWQVVTALHQRQL 198
>gi|22749303 hypothetical protein LOC196477 [Homo sapiens]
Length = 406
Score = 61.2 bits (147), Expect = 1e-09
Identities = 47/122 (38%), Positives = 59/122 (48%), Gaps = 23/122 (18%)
Query: 172 RKLLNVLKEYIAEKQKDDEAEEAEAAAAAAEAAAAAEAAAAAAEVIVVEDEEEEEKEEEE 231
+ L +L E EK+ DDE E + A EA+ E+EEE E EEEE
Sbjct: 269 QSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEAS---------------EEEEEVEDEEEE 313
Query: 232 EKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQIKAFQEKQKRWQQPT 291
++EEEEE EE EEGEE E EEEE EEEEE EE + +E + P
Sbjct: 314 VEDEEEEEVEEAEYVEEGEE--------ELEEEELEEEEEVLEENEQRGEEFHLPLEMPL 365
Query: 292 GV 293
+
Sbjct: 366 SI 367
Score = 54.3 bits (129), Expect = 1e-07
Identities = 35/91 (38%), Positives = 50/91 (54%), Gaps = 9/91 (9%)
Query: 208 EAAAAAAEVIVVEDEEEEEKEEEE---------EKEEEEEEGEEEGGGEEGEEGGGGGEG 258
E + A ++V E+EE++ +EEE E EEEEE E+E E EE E
Sbjct: 266 EENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAKEASEEEEEVEDEEEEVEDEEEEEVEEA 325
Query: 259 EETEEEEEEEEEEEEEEQIKAFQEKQKRWQQ 289
E EE EEE EEEE EE+ + +E ++R ++
Sbjct: 326 EYVEEGEEELEEEELEEEEEVLEENEQRGEE 356
Score = 42.4 bits (98), Expect = 6e-04
Identities = 26/91 (28%), Positives = 48/91 (52%), Gaps = 15/91 (16%)
Query: 217 IVVEDEEEEEKEEEEEKEEEEEEGEEEGGGEEGEEGGGGGEGEETEEEEEEEEEEEEEEQ 276
++VE+EEE++ ++EEE ++E + +E E EEE E+EEEE E+E+
Sbjct: 274 LLVEEEEEKKNDDEEEYDQEVCDAKE---------------ASEEEEEVEDEEEEVEDEE 318
Query: 277 IKAFQEKQKRWQQPTGVRSWRLREMKPLLEQ 307
+ +E + + + L E + +LE+
Sbjct: 319 EEEVEEAEYVEEGEEELEEEELEEEEEVLEE 349
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.301 0.121 0.318
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,186,995
Number of Sequences: 37866
Number of extensions: 907408
Number of successful extensions: 76276
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1578
Number of HSP's successfully gapped in prelim test: 785
Number of HSP's that attempted gapping in prelim test: 13818
Number of HSP's gapped (non-prelim): 20979
length of query: 332
length of database: 18,247,518
effective HSP length: 103
effective length of query: 229
effective length of database: 14,347,320
effective search space: 3285536280
effective search space used: 3285536280
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.