BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|27735067 hypothetical protein LOC126353 [Homo sapiens] (679 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|27735067 hypothetical protein LOC126353 [Homo sapiens] 1384 0.0 gi|50659104 RAB11 family interacting protein 1 isoform 3 [Homo s... 47 8e-05 gi|6005709 PALM2-AKAP2 protein isoform 1 [Homo sapiens] 46 1e-04 gi|148762940 DVL-binding protein DAPLE [Homo sapiens] 43 0.001 gi|178557734 microtubule-associated protein tau isoform 6 [Homo ... 42 0.001 gi|82534351 microtubule-associated protein tau isoform 1 [Homo s... 42 0.001 gi|22325356 PALM2-AKAP2 protein isoform 2 [Homo sapiens] 42 0.002 gi|211971074 A kinase (PRKA) anchor protein 2 isoform 2 [Homo sa... 42 0.002 gi|51873058 A kinase (PRKA) anchor protein 2 isoform 1 [Homo sap... 42 0.002 gi|91208420 bassoon protein [Homo sapiens] 40 0.007 gi|150170729 microtubule associated serine/threonine kinase 3 [H... 39 0.012 gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 39 0.016 gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens] 39 0.021 gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo ... 38 0.027 gi|163310749 LIM and calponin homology domains 1 isoform e [Homo... 38 0.035 gi|163310747 LIM and calponin homology domains 1 isoform d [Homo... 38 0.035 gi|163310745 LIM and calponin homology domains 1 isoform c [Homo... 38 0.035 gi|163310743 LIM and calponin homology domains 1 isoform b [Homo... 38 0.035 gi|163310741 LIM and calponin homology domains 1 isoform a [Homo... 38 0.035 gi|221139926 NHS-like 1 [Homo sapiens] 37 0.046 gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 37 0.060 gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Ho... 37 0.078 gi|51464815 PREDICTED: similar to hCG1745223 [Homo sapiens] 36 0.10 gi|225735627 disco-interacting protein 2A isoform f [Homo sapiens] 36 0.13 gi|41281612 zinc finger protein 828 [Homo sapiens] 36 0.13 gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] 36 0.13 gi|118600967 shroom family member 4 [Homo sapiens] 35 0.17 gi|110349719 titin isoform N2-A [Homo sapiens] 35 0.17 gi|22547204 hairless protein isoform a [Homo sapiens] 35 0.17 gi|22547207 hairless protein isoform b [Homo sapiens] 35 0.17 >gi|27735067 hypothetical protein LOC126353 [Homo sapiens] Length = 679 Score = 1384 bits (3583), Expect = 0.0 Identities = 679/679 (100%), Positives = 679/679 (100%) Query: 1 MDRVTRYPILGIPQAHRGTGLVLDGDTSYTYHLVCMGPEASGWGQDEPQTWPTDHRAQQG 60 MDRVTRYPILGIPQAHRGTGLVLDGDTSYTYHLVCMGPEASGWGQDEPQTWPTDHRAQQG Sbjct: 1 MDRVTRYPILGIPQAHRGTGLVLDGDTSYTYHLVCMGPEASGWGQDEPQTWPTDHRAQQG 60 Query: 61 VQRQGVSYSVHAYTGQPSPRGLHSENREDEGWQVYRLGARDAHQGRPTWALRPEDGEDKE 120 VQRQGVSYSVHAYTGQPSPRGLHSENREDEGWQVYRLGARDAHQGRPTWALRPEDGEDKE Sbjct: 61 VQRQGVSYSVHAYTGQPSPRGLHSENREDEGWQVYRLGARDAHQGRPTWALRPEDGEDKE 120 Query: 121 MKTYRLDAGDADPRRLCDLERERWAVIQGQAVRKSSTVATLQGTPDHGDPRTPGPPRSTP 180 MKTYRLDAGDADPRRLCDLERERWAVIQGQAVRKSSTVATLQGTPDHGDPRTPGPPRSTP Sbjct: 121 MKTYRLDAGDADPRRLCDLERERWAVIQGQAVRKSSTVATLQGTPDHGDPRTPGPPRSTP 180 Query: 181 LEENVVDREQIDFLAARQQFLSLEQANKGAPHSSPARGTPAGTTPGASQAPKAFNKPHLA 240 LEENVVDREQIDFLAARQQFLSLEQANKGAPHSSPARGTPAGTTPGASQAPKAFNKPHLA Sbjct: 181 LEENVVDREQIDFLAARQQFLSLEQANKGAPHSSPARGTPAGTTPGASQAPKAFNKPHLA 240 Query: 241 NGHVVPIKPQVKGVVREENKVRAVPTWASVQVVDDPGSLASVESPGTPKETPIEREIRLA 300 NGHVVPIKPQVKGVVREENKVRAVPTWASVQVVDDPGSLASVESPGTPKETPIEREIRLA Sbjct: 241 NGHVVPIKPQVKGVVREENKVRAVPTWASVQVVDDPGSLASVESPGTPKETPIEREIRLA 300 Query: 301 QEREADLREQRGLRQATDHQELVEIPTRPLLTKLSLITAPRRERGRPSLYVQRDIVQETQ 360 QEREADLREQRGLRQATDHQELVEIPTRPLLTKLSLITAPRRERGRPSLYVQRDIVQETQ Sbjct: 301 QEREADLREQRGLRQATDHQELVEIPTRPLLTKLSLITAPRRERGRPSLYVQRDIVQETQ 360 Query: 361 REEDHRREGLHVGRASTPDWVSEGPQPGLRRALSSDSILSPAPDARAADPAPEVRKVNRI 420 REEDHRREGLHVGRASTPDWVSEGPQPGLRRALSSDSILSPAPDARAADPAPEVRKVNRI Sbjct: 361 REEDHRREGLHVGRASTPDWVSEGPQPGLRRALSSDSILSPAPDARAADPAPEVRKVNRI 420 Query: 421 PPDAYQPYLSPGTPQLEFSAFGAFGKPSSLSTAEAKAATSPKATMSPRHLSESSGKPLST 480 PPDAYQPYLSPGTPQLEFSAFGAFGKPSSLSTAEAKAATSPKATMSPRHLSESSGKPLST Sbjct: 421 PPDAYQPYLSPGTPQLEFSAFGAFGKPSSLSTAEAKAATSPKATMSPRHLSESSGKPLST 480 Query: 481 KQEASKPPRGCPQANRGVVRWEYFRLRPLRFRAPDEPQQAQVPHVWGWEVAGAPALRLQK 540 KQEASKPPRGCPQANRGVVRWEYFRLRPLRFRAPDEPQQAQVPHVWGWEVAGAPALRLQK Sbjct: 481 KQEASKPPRGCPQANRGVVRWEYFRLRPLRFRAPDEPQQAQVPHVWGWEVAGAPALRLQK 540 Query: 541 SQSSDLLERERESVLRREQEVAEERRNALFPEVFSPTPDENSDQNSRSSSQASGITGSYS 600 SQSSDLLERERESVLRREQEVAEERRNALFPEVFSPTPDENSDQNSRSSSQASGITGSYS Sbjct: 541 SQSSDLLERERESVLRREQEVAEERRNALFPEVFSPTPDENSDQNSRSSSQASGITGSYS 600 Query: 601 VSESPFFSPIHLHSNVAWTVEDPVDSAPPGQRKKEQWYAGINPSDGINSEVLEAIRVTRH 660 VSESPFFSPIHLHSNVAWTVEDPVDSAPPGQRKKEQWYAGINPSDGINSEVLEAIRVTRH Sbjct: 601 VSESPFFSPIHLHSNVAWTVEDPVDSAPPGQRKKEQWYAGINPSDGINSEVLEAIRVTRH 660 Query: 661 KNAMAERWESRIYASEEDD 679 KNAMAERWESRIYASEEDD Sbjct: 661 KNAMAERWESRIYASEEDD 679 >gi|50659104 RAB11 family interacting protein 1 isoform 3 [Homo sapiens] Length = 1283 Score = 46.6 bits (109), Expect = 8e-05 Identities = 100/453 (22%), Positives = 157/453 (34%), Gaps = 100/453 (22%) Query: 216 ARGTPAGTTPGASQAPKAFNKPHL----------------ANGHVVPIKPQVKGVVREEN 259 A+G ++P +S +PK F K HL G + + + ++ Sbjct: 331 AKGEIKDSSPSSSPSPKGFRKKHLFSSTENLAAGSWKEPAEGGGLSSDRQLSESSTKDSL 390 Query: 260 KVRAVPTWASVQVVDDPGSLASVESPGTPKETPIEREIRLAQEREADL------------ 307 K +P++ +V G L +P + T +E + + R + L Sbjct: 391 KSMTLPSYRPAPLVS--GDLRENMAPANSEATKEAKESKKPESRRSSLLSLMTGKKDVAK 448 Query: 308 ------------REQRGLRQATDHQELVEIPTRPLLTKLSLITAPRRERGRPSLYVQRDI 355 RE+ G+ E P L+ + TA R SL + D+ Sbjct: 449 GSEGENPLTVPGREKEGMLMGVKPGEDASGPAEDLVRRSEKDTAAVVSRQGSSLNLFEDV 508 Query: 356 -VQETQREEDHRREGLHVGRASTPDWVSEGPQPGLRRALSSDSILSP-APDARAADP--- 410 + E + E + + E P+P I SP AP RA P Sbjct: 509 QITEPEAEPESKSE----------------PRP---------PISSPRAPQTRAVKPRLE 543 Query: 411 -APEVRKVNRIPPDAYQPYLSPGTPQLEFSAFGAFGKPSSLS-TAEAKAATSPKATMSPR 468 +PE + R+P P P P S+ G PS L A+ +++ SP S Sbjct: 544 VSPEAQPTARLPSPTDSPSSLPPLP----SSSGQASVPSELGHGADTQSSESPSVFSS-- 597 Query: 469 HLSESSGKPLSTKQEASKPPRGCPQANRGVVRWEYFRLRPLRFRAPDEPQQAQVPHVWGW 528 LS P+ST S P P +RG + E PL +A + + G Sbjct: 598 -LSSPIAAPIST----STPIESWPLVDRGQAKSEG---PPLLPKAELQTESLTPVPNSGS 649 Query: 529 EVAGA----PALRLQKSQSSDLLERERE-------SVLRREQEVAEERRNALFPEVFSPT 577 V G+ P+ K L+ R RE S L E+ + E+ E Sbjct: 650 SVLGSLFKQPSFPANKGTEDSLMGRTRETGTEKNTSSLELEESLPEQPETGRQEEELPRF 709 Query: 578 PDENSDQNSRSSSQASGITGSYSVSESPFFSPI 610 P + D S SS +A + + S+S SP+ Sbjct: 710 PCKKQDY-SPSSGEAQEVPFALSLSSDGAVSPV 741 >gi|6005709 PALM2-AKAP2 protein isoform 1 [Homo sapiens] Length = 1103 Score = 46.2 bits (108), Expect = 1e-04 Identities = 45/167 (26%), Positives = 72/167 (43%), Gaps = 19/167 (11%) Query: 530 VAGAPALRLQKSQSSDLLERERESVLRREQEVAEERRNALFPEVFSPTPDENSDQNSRSS 589 + G LR +K ++ ++E E + RE+E+ +R+ + SP SR+ Sbjct: 936 MVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQ--VLQSTQSPRTKNAPSLPSRTC 993 Query: 590 SQ-ASGITGSYS-----VSESPFFSPIHLHSNVAWT----------VED-PVDSAPPGQR 632 + A G +E P P A T +ED + +R Sbjct: 994 YKTAPGKIEKVKPPPSPTTEGPSLQPDLAPEEAAGTQRPKNLMQTLMEDYETHKSKRRER 1053 Query: 633 KKEQWYAGINPSDGINSEVLEAIRVTRHKNAMAERWESRIYASEEDD 679 + Y S + SEVLEA RV R K+A+A RWE+ IYA++E++ Sbjct: 1054 MDDSSYTSKLLSCKVTSEVLEATRVNRRKSALALRWEAGIYANQEEE 1100 Score = 35.0 bits (79), Expect = 0.23 Identities = 18/40 (45%), Positives = 23/40 (57%) Query: 293 IEREIRLAQEREADLREQRGLRQATDHQELVEIPTRPLLT 332 IE EIR AQERE +L+ QR + Q+T P+ P T Sbjct: 953 IEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRT 992 >gi|148762940 DVL-binding protein DAPLE [Homo sapiens] Length = 2028 Score = 42.7 bits (99), Expect = 0.001 Identities = 61/249 (24%), Positives = 92/249 (36%), Gaps = 32/249 (12%) Query: 387 PGLRRALSSDSILSPA-PDARAADPAPEVRKVN-RIPPDAYQPYLSPGTPQLEFSAF--G 442 P R L SD + P A P P +K ++P + P + P E G Sbjct: 1689 PSCRDDLLSDYFRKASDPPAIGGQPGPPAKKEGAKMPTNFVAPTVKMAAPTSEGRPLKPG 1748 Query: 443 AFGKPS-SLSTAEAKAATSPKATMSPRHLSESSGKPLSTKQEASKPPRGCPQANRGVVRW 501 + KP+ L+ AEA + +P+ P+ LS L ++A PP A+R Sbjct: 1749 QYVKPNFRLTEAEAPPSVAPRQAQPPQSLS------LGRPRQAPVPPASHAPASRSASLS 1802 Query: 502 EYFRLRP---LRFRAPD-----EPQQAQVPHVWGWEVAGAPALRLQKSQSSDLLERERES 553 F L LR P+ PQ+ P G G+ L+ SS L RER Sbjct: 1803 RAFSLASADLLRASGPEACKQESPQKLGAPEALGGRETGSHTLQSPAPPSSHSLARERTP 1862 Query: 554 VLRR----------EQEVAEERRNALFP---EVFSPTPDENSDQNSRSSSQASGITGSYS 600 ++ + + RR +L P E +P + ++ + GS S Sbjct: 1863 LVGKAGSSCQGPGPRSRPLDTRRFSLAPPKEERLAPLHQSATAPAIATAGAGAAAAGSGS 1922 Query: 601 VSESPFFSP 609 S+ FSP Sbjct: 1923 NSQLLHFSP 1931 >gi|178557734 microtubule-associated protein tau isoform 6 [Homo sapiens] Length = 776 Score = 42.4 bits (98), Expect = 0.001 Identities = 55/240 (22%), Positives = 89/240 (37%), Gaps = 44/240 (18%) Query: 283 ESPGTPKETPIEREIRLAQEREADLRE----QRGLRQATDHQELVEIPTRP--------- 329 E PG+ +E +R++ + +++ + Q G T +E IP P Sbjct: 210 ERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPV 269 Query: 330 -LLTKLSLITAPRRERGRPSLYVQR------------DIVQETQREEDHRREGLHVGRAS 376 L+K+S P E PS+ + +I Q+E+ H E H+GRA+ Sbjct: 270 DFLSKVST-EIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEE--HLGRAA 326 Query: 377 TPDWVSEGPQ---PGLRRALSSDSILSPAPDARAADPAPEVRKVNRIPPDAYQPYLSPGT 433 P EGP+ P L + P P + AP + V+R+ P L Sbjct: 327 FPGAPGEGPEARGPSLGEDTKEADL--PEPSEKQPAAAPRGKPVSRV------PQLKARM 378 Query: 434 PQLEFSAFGAFGKPSSLSTAEAKAATSPKATMSPRHLSESSGKPLSTKQEASKPPRGCPQ 493 G+ K + ST + + +SP+H + S PL P CP+ Sbjct: 379 VSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSS----PAVCPE 434 >gi|82534351 microtubule-associated protein tau isoform 1 [Homo sapiens] Length = 758 Score = 42.4 bits (98), Expect = 0.001 Identities = 55/240 (22%), Positives = 89/240 (37%), Gaps = 44/240 (18%) Query: 283 ESPGTPKETPIEREIRLAQEREADLRE----QRGLRQATDHQELVEIPTRP--------- 329 E PG+ +E +R++ + +++ + Q G T +E IP P Sbjct: 210 ERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPV 269 Query: 330 -LLTKLSLITAPRRERGRPSLYVQR------------DIVQETQREEDHRREGLHVGRAS 376 L+K+S P E PS+ + +I Q+E+ H E H+GRA+ Sbjct: 270 DFLSKVST-EIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEE--HLGRAA 326 Query: 377 TPDWVSEGPQ---PGLRRALSSDSILSPAPDARAADPAPEVRKVNRIPPDAYQPYLSPGT 433 P EGP+ P L + P P + AP + V+R+ P L Sbjct: 327 FPGAPGEGPEARGPSLGEDTKEADL--PEPSEKQPAAAPRGKPVSRV------PQLKARM 378 Query: 434 PQLEFSAFGAFGKPSSLSTAEAKAATSPKATMSPRHLSESSGKPLSTKQEASKPPRGCPQ 493 G+ K + ST + + +SP+H + S PL P CP+ Sbjct: 379 VSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSS----PAVCPE 434 >gi|22325356 PALM2-AKAP2 protein isoform 2 [Homo sapiens] Length = 1090 Score = 42.0 bits (97), Expect = 0.002 Identities = 42/160 (26%), Positives = 69/160 (43%), Gaps = 18/160 (11%) Query: 530 VAGAPALRLQKSQSSDLLERERESVLRREQEVAEERRNALFPEVFSPTPDENSDQNSRSS 589 + G LR +K ++ ++E E + RE+E+ +R+ + SP SR+ Sbjct: 936 MVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQ--VLQSTQSPRTKNAPSLPSRTC 993 Query: 590 SQ-ASGITGSYSVSESPFFSPIHLHSNVAWTVEDPVDSAPPGQRKKE---------QWYA 639 + A G SP L ++A + A QR K + + Sbjct: 994 YKTAPGKIEKVKPPPSPTTEGPSLQPDLA------PEEAAGTQRPKNLMQTLMEDYETHK 1047 Query: 640 GINPSDGINSEVLEAIRVTRHKNAMAERWESRIYASEEDD 679 +S VLEA RV R K+A+A RWE+ IYA++E++ Sbjct: 1048 SKRRERMDDSSVLEATRVNRRKSALALRWEAGIYANQEEE 1087 Score = 35.0 bits (79), Expect = 0.23 Identities = 18/40 (45%), Positives = 23/40 (57%) Query: 293 IEREIRLAQEREADLREQRGLRQATDHQELVEIPTRPLLT 332 IE EIR AQERE +L+ QR + Q+T P+ P T Sbjct: 953 IEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRT 992 >gi|211971074 A kinase (PRKA) anchor protein 2 isoform 2 [Homo sapiens] Length = 859 Score = 42.0 bits (97), Expect = 0.002 Identities = 42/160 (26%), Positives = 69/160 (43%), Gaps = 18/160 (11%) Query: 530 VAGAPALRLQKSQSSDLLERERESVLRREQEVAEERRNALFPEVFSPTPDENSDQNSRSS 589 + G LR +K ++ ++E E + RE+E+ +R+ + SP SR+ Sbjct: 705 MVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQ--VLQSTQSPRTKNAPSLPSRTC 762 Query: 590 SQ-ASGITGSYSVSESPFFSPIHLHSNVAWTVEDPVDSAPPGQRKKE---------QWYA 639 + A G SP L ++A + A QR K + + Sbjct: 763 YKTAPGKIEKVKPPPSPTTEGPSLQPDLA------PEEAAGTQRPKNLMQTLMEDYETHK 816 Query: 640 GINPSDGINSEVLEAIRVTRHKNAMAERWESRIYASEEDD 679 +S VLEA RV R K+A+A RWE+ IYA++E++ Sbjct: 817 SKRRERMDDSSVLEATRVNRRKSALALRWEAGIYANQEEE 856 Score = 35.0 bits (79), Expect = 0.23 Identities = 18/40 (45%), Positives = 23/40 (57%) Query: 293 IEREIRLAQEREADLREQRGLRQATDHQELVEIPTRPLLT 332 IE EIR AQERE +L+ QR + Q+T P+ P T Sbjct: 722 IEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRT 761 >gi|51873058 A kinase (PRKA) anchor protein 2 isoform 1 [Homo sapiens] Length = 948 Score = 42.0 bits (97), Expect = 0.002 Identities = 42/160 (26%), Positives = 69/160 (43%), Gaps = 18/160 (11%) Query: 530 VAGAPALRLQKSQSSDLLERERESVLRREQEVAEERRNALFPEVFSPTPDENSDQNSRSS 589 + G LR +K ++ ++E E + RE+E+ +R+ + SP SR+ Sbjct: 794 MVGPFKLRSRKQRTLSMIEEEIRAAQEREEELKRQRQ--VLQSTQSPRTKNAPSLPSRTC 851 Query: 590 SQ-ASGITGSYSVSESPFFSPIHLHSNVAWTVEDPVDSAPPGQRKKE---------QWYA 639 + A G SP L ++A + A QR K + + Sbjct: 852 YKTAPGKIEKVKPPPSPTTEGPSLQPDLA------PEEAAGTQRPKNLMQTLMEDYETHK 905 Query: 640 GINPSDGINSEVLEAIRVTRHKNAMAERWESRIYASEEDD 679 +S VLEA RV R K+A+A RWE+ IYA++E++ Sbjct: 906 SKRRERMDDSSVLEATRVNRRKSALALRWEAGIYANQEEE 945 Score = 35.0 bits (79), Expect = 0.23 Identities = 18/40 (45%), Positives = 23/40 (57%) Query: 293 IEREIRLAQEREADLREQRGLRQATDHQELVEIPTRPLLT 332 IE EIR AQERE +L+ QR + Q+T P+ P T Sbjct: 811 IEEEIRAAQEREEELKRQRQVLQSTQSPRTKNAPSLPSRT 850 >gi|91208420 bassoon protein [Homo sapiens] Length = 3926 Score = 40.0 bits (92), Expect = 0.007 Identities = 35/113 (30%), Positives = 51/113 (45%), Gaps = 17/113 (15%) Query: 384 GPQPGLRRALSSDSILSPAPDARAADPAPEVRKVNRIPPDAYQPYLS-PGTPQLEFSAFG 442 GPQPG R+A ++ + P P A+AA P PEV +V+ PP +P + P P E A Sbjct: 271 GPQPGSRQAETARATSVPGP-AQAAAP-PEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKS 328 Query: 443 AFGKPSSLSTAE--------------AKAATSPKATMSPRHLSESSGKPLSTK 481 A P+ L E A T MS + +++ G+P +K Sbjct: 329 ATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSK 381 Score = 37.0 bits (84), Expect = 0.060 Identities = 56/223 (25%), Positives = 90/223 (40%), Gaps = 45/223 (20%) Query: 276 PGSLASVESPGTPKETPIEREIRLAQEREADLREQRGL----RQATDHQELVEIPTRPLL 331 P SL+S+E + +R Q+R+A R L +++ +EL E LL Sbjct: 996 PTSLSSLEEDSDSSPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELRE--EEELL 1053 Query: 332 TKLSLITAPRRERGRPSLYVQRDIVQETQREEDHRREGLHVGRASTPDWVSEGPQPGLRR 391 + + ++R R + ++T+R+++ R R+ TP Sbjct: 1054 REQEKMREVEQQRIRST-------ARKTRRDKEELRAQRRRERSKTPP------------ 1094 Query: 392 ALSSDSILSPAPDARAADP---APEVRKVNRIPPDAYQPYLSPGTPQLEFSAFGAFGKPS 448 S LSP DA + A E+ +++R Y P +P L+ A G PS Sbjct: 1095 -----SNLSPIEDASPTEELRQAAEMEELHRSSCSEYSP-----SPSLDSEAEALDGGPS 1144 Query: 449 SL--STAEAKAAT-----SPKATMSPRHLSESSGKPLSTKQEA 484 L S +E T SP T S + SSG+PL + +EA Sbjct: 1145 RLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEEA 1187 Score = 33.1 bits (74), Expect = 0.87 Identities = 40/153 (26%), Positives = 59/153 (38%), Gaps = 9/153 (5%) Query: 410 PAPEVRKV-NRIPPDAYQPYLSPGTPQLEFSAFGAFGKPSSLSTAEAKAATSPKATMSPR 468 PAP + + +PP YL G P A GA G PS A P T +P Sbjct: 2262 PAPSRFPIASSVPPAEGPVYL--GKPAAA-KAPGA-GGPSRPEMPVGAAREEPLPTTTPA 2317 Query: 469 HLSESSGKPLSTKQEASKPPR-GCPQANRGVVRWEYFRLRPLRFRAPDEPQQAQVPHVWG 527 + E++G P KPP P G + F + +E Q+ Q + Sbjct: 2318 AIKEAAGAPAPAPLAGQKPPADAAPGGGSGALSRPGFEKEE---ASQEERQRKQQEQLLQ 2374 Query: 528 WEVAGAPALRLQKSQSSDLLERERESVLRREQE 560 E +L++ + + LERER + R +E Sbjct: 2375 LERERVELEKLRQLRLQEELERERVELQRHREE 2407 >gi|150170729 microtubule associated serine/threonine kinase 3 [Homo sapiens] Length = 1309 Score = 39.3 bits (90), Expect = 0.012 Identities = 44/170 (25%), Positives = 63/170 (37%), Gaps = 17/170 (10%) Query: 331 LTKLSLITAPRRERGRPSLYVQRDIVQETQREEDHRREGLH--VGRASTPDWVSEGPQPG 388 L S+ P R+ +R + +RE RR+ L + + ++ S G Sbjct: 1037 LENTSIKVGPARKNVAKGRMARRS-KRSRRRETQDRRKSLFKKISKQTSVLHTSRSFSSG 1095 Query: 389 LRRALSSDSIL--------SPAPDARAADPAPEV-RKVNRIPPDAYQPYLSPGTPQLEFS 439 L +LSS L SP+P PAP+V PP A SP +P Sbjct: 1096 LHHSLSSSESLPGSPTHSLSPSPTTPCRSPAPDVPADTTASPPSASPSSSSPASP----- 1150 Query: 440 AFGAFGKPSSLSTAEAKAATSPKATMSPRHLSESSGKPLSTKQEASKPPR 489 A +PSSL AK T + S PL+ ++ PPR Sbjct: 1151 AAAGHTRPSSLHGLAAKLGPPRPKTGRRKSTSSIPPSPLACPPISAPPPR 1200 >gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] Length = 904 Score = 38.9 bits (89), Expect = 0.016 Identities = 57/226 (25%), Positives = 86/226 (38%), Gaps = 15/226 (6%) Query: 366 RREGLHVGRASTPDWVSEGPQPGLRRALSSDSILSPAPDARAADPAPEVRKVNRIPPDAY 425 RR R S P P P +R +S P P RA+ P R+V+ PP Sbjct: 587 RRRSPSPRRYSPPIQRRYSPSPPPKRRTASPP---PPPKRRASPSPPPKRRVSHSPPPKQ 643 Query: 426 Q--PYLSPGTPQLEFSAFGAFGKPSSLSTAEAKAATSPKA-TMSPR-HLSESSGKPLSTK 481 + P +P L S+ G S ST EA++ K + SPR ++S P + Sbjct: 644 RSSPVTKRRSPSL--SSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVR 701 Query: 482 QEASKPP--RGCPQANRGVVRWEYFRLRPLRFRAPDEPQQAQVPHV-WGWEVAGAPALRL 538 + AS P R P + +R P + + P V V V+G+P Sbjct: 702 RGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAA 761 Query: 539 QKSQSSDLLERERESVLRREQEVAEERRNALFPEVFSPTPDENSDQ 584 +K + + + V ++ + P SP+P NSDQ Sbjct: 762 KKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTP---SPSPPRNSDQ 804 Score = 36.6 bits (83), Expect = 0.078 Identities = 103/510 (20%), Positives = 171/510 (33%), Gaps = 73/510 (14%) Query: 133 PRRLCDLERERWAVIQGQAVRKSSTVATLQGTPDHGDP-RTPGPPRSTPLEENVVDREQI 191 PRR+ R R + + R+SS A+L G+ R+ PP+ P + R+ Sbjct: 329 PRRMPPPPRHRRSRSPVRRRRRSS--ASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRK-- 384 Query: 192 DFLAARQQFLSLEQANKGAPHSSPARG----TPAGTTPGA---SQAPKAFNKPHLANGHV 244 + +P +SP R +P T P S P+ N+ + V Sbjct: 385 --------------TRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSV 430 Query: 245 VPIKPQVKGVVREENKVRAVPTWA--------SVQVVDDPGSLASVESPGTPKETPIERE 296 P + K + + R P+ A S D G +A+ +S + R+ Sbjct: 431 SPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADS--VQQRRQYRRQ 488 Query: 297 IRLAQEREADLREQRGLRQATDHQELVEIPTR----------PLLTKLSLITAPR-RERG 345 + + R H + E+ R P K T+PR R R Sbjct: 489 NQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRR 548 Query: 346 RPSLYVQRDIVQETQREEDHRREGLHVGRASTPDWVSEGPQPGLRRALSSDSILSPAPDA 405 PS R + RR R TP P P RR S SP P Sbjct: 549 SPSPPPTRRRRSPSPAPPPRRR------RTPTPPPRRRTPSPPPRRRSPSPRRYSP-PIQ 601 Query: 406 RAADPAPEVRKVNRIPPDAYQPYLSPGTPQLEFSAFGAFGKPSSLSTAEAKA---ATSPK 462 R P+P ++ PP + SP P + K S + ++ ++ + Sbjct: 602 RRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHR 661 Query: 463 ATMSPRHLSESSGKPLSTKQEASKPPRGCPQANRGVVRWEYFRLRPLRFRAPDEPQQAQV 522 SP + + P K+ + P PQ + P+R A PQ+ Q Sbjct: 662 KGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSP--------PPVRRGASSSPQRRQS 713 Query: 523 PHVWGWEVAGAPALRLQKSQSSDLLERERESVLRREQEVAEERRNALFPEVFS---PTPD 579 P + P R+ ++ +++ + + V+ R + PE + P P Sbjct: 714 P-----SPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPP 768 Query: 580 ENSDQNSRSSSQASGITGSYSVSESPFFSP 609 S S++ + + + S +P SP Sbjct: 769 SPVQSQSPSTNWSPAVPVKKAKSPTPSPSP 798 Score = 30.0 bits (66), Expect = 7.3 Identities = 50/236 (21%), Positives = 89/236 (37%), Gaps = 30/236 (12%) Query: 295 REIRLAQEREADLREQRGLRQATDHQELVEIPTRPLLTKLSLITAPRRERGRPSLYVQRD 354 ++ ++ QE+ A +++Q + D +E K +PRR + R +R Sbjct: 132 KQRQIEQEKLASMKKQDEDKDKRDKEE-----KESSREKRERSRSPRRRKSRSPSPRRRS 186 Query: 355 IVQETQREEDHRREGLHVGRASTPDWVSEGPQPGLRRALSSDSILSPAPDARAADPAPEV 414 +R+ H R H ++ +P E + L S+ P + A ++ Sbjct: 187 SPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEK--TPELPEPSVKVKEPSVQEATSTSDI 244 Query: 415 RKVNRIPPDAYQPYLSPGTPQLEFSAFGAFGK----PSSLSTAEAKAAT---SPKATMSP 467 KV + +P P P E ++ K P S S +++++ T SP T P Sbjct: 245 LKVPK-----PEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHT-RP 298 Query: 468 RHLSESSGKPLSTKQEASKPPRGCPQANRGVVRWEYFRLRPLRFRAPDEPQQAQVP 523 R S + S ++ S PR P R R P R P ++++ P Sbjct: 299 RRRHRSRSRSYSPRRRPS--PRRRPSPRR--------RTPPRRMPPPPRHRRSRSP 344 >gi|151108509 Rho GTPase-activating protein RICH2 [Homo sapiens] Length = 818 Score = 38.5 bits (88), Expect = 0.021 Identities = 50/184 (27%), Positives = 71/184 (38%), Gaps = 29/184 (15%) Query: 343 ERGRPSLYVQRDIVQETQREEDHRREGLHVG-RASTPDWVSE-GPQPGLRRALSSDSILS 400 E+ R L V D + ++D R+ +G R +WV+ G G + + + S+ Sbjct: 486 EQARRPLSVATDNMMLEFYKKDGLRKIQSMGVRVMDTNWVARRGSSAGRKVSCAPPSMQP 545 Query: 401 PAPDARAADPAPEVRKVNRIPPDAYQPYLSPGTPQLEFSAFGAFGKPSSLSTAEAKAATS 460 PAP A A P P P QP SP P L S G P ST ++K Sbjct: 546 PAPPAELAAPLPS--------PLPEQPLDSPAAPALSPSGLGLQPGPERTSTTKSK---- 593 Query: 461 PKATMSPRHLSESSGKPLSTKQEASKPPRGCPQANRGVVRWEYFRLRPLRFRAPDEPQQA 520 +SP S G P S++ A + P A G +P +P +P Sbjct: 594 ---ELSPG--SAQKGSPGSSQGTACAGTQ--PGAQPGA--------QPGASPSPSQPPAD 638 Query: 521 QVPH 524 Q PH Sbjct: 639 QSPH 642 >gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo sapiens] Length = 1386 Score = 38.1 bits (87), Expect = 0.027 Identities = 52/227 (22%), Positives = 82/227 (36%), Gaps = 29/227 (12%) Query: 107 PTWALRPEDGEDKEMKTYRLDAGDADPRRLCDLERERWAVIQ----GQAVRKSSTVATLQ 162 P+ L +G ++E++ G ++P C ER + + G + S T Sbjct: 1090 PSCELSCLEGPEEELE------GSSEPEEWCPPMPERSHLTEPSSSGGCLVTPSRRETPS 1143 Query: 163 GTPDHGD----------PRTPGPPRSTPLEENVVDREQI---DFLAARQQFLSLEQANKG 209 TP +G P P PP P + R + L+ Q L + +A Sbjct: 1144 PTPSYGQQSTATLTPSPPDPPQPPTDMPHLHQMPRRVPLGPSSPLSVSQPMLGIREARPA 1203 Query: 210 APHSSPARGTPAGTTPGASQAPKAFNKPHLANGHVVPIKPQVKGVVREENKVRAVPTWAS 269 + PA +P S A A + NG + P P R K +A+P Sbjct: 1204 GLGAGPAASPHLSPSPAPSTASSAPGRTWQGNGEMTP--PLQGPRARFRKKPKALP---- 1257 Query: 270 VQVVDDPGSLASVESPGTPKETPIEREIRLAQEREADLREQRGLRQA 316 + + PG L P +E E+R A + RE+ G R+A Sbjct: 1258 YRRENSPGDLPPPPLPPPEEEASWALELRAAGSMSSLERERSGERKA 1304 >gi|163310749 LIM and calponin homology domains 1 isoform e [Homo sapiens] Length = 890 Score = 37.7 bits (86), Expect = 0.035 Identities = 70/319 (21%), Positives = 124/319 (38%), Gaps = 35/319 (10%) Query: 293 IEREIRLAQER-EADLREQRGLRQATDHQELVEIPTRPLLTKLSLITAPRRERGRPSLYV 351 I ++R ++ + DL + R++ + + R + KL ER R S+ Sbjct: 187 INNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSER-RKSIKT 245 Query: 352 QRDIVQETQREEDHRREGLHVGRASTPDWVSEGP-QPGLRRALSSDSILS----PAPDAR 406 R+IVQE +R E E R+ +EG Q + R S+++L P R Sbjct: 246 YREIVQEKERRERELHEAYKNARSQEE---AEGILQQYIERFTISEAVLERLEMPKILER 302 Query: 407 AADPAPEVRKVNRIP-PDAYQPYLSPGTPQLEFSAFGAFGKPSSLSTAEAKAATSPKATM 465 + P + P P Y S P+ + + S L T+ + + SP T+ Sbjct: 303 SHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTV 362 Query: 466 SPRHLSESSGKPLSTKQEASKPPRGCPQANRGVVRWEYFRLRPLRFRAPDEPQQAQVPHV 525 +P+ + + KP S + + + + V E +E ++ + P V Sbjct: 363 TPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVH--------REEEKERECPTV 414 Query: 526 WGWEVAGAPALRLQKSQSSDLLERERESVLRREQ-----EVAEERRNALFPEVFSPT--- 577 APA L KSQ + + R S L +Q E+ ++ N++ E+ + T Sbjct: 415 -------APAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKT 467 Query: 578 -PDENSDQNSRSSSQASGI 595 P+ D+N S+ I Sbjct: 468 EPNSQEDKNDGGKSRKGNI 486 >gi|163310747 LIM and calponin homology domains 1 isoform d [Homo sapiens] Length = 902 Score = 37.7 bits (86), Expect = 0.035 Identities = 70/319 (21%), Positives = 124/319 (38%), Gaps = 35/319 (10%) Query: 293 IEREIRLAQER-EADLREQRGLRQATDHQELVEIPTRPLLTKLSLITAPRRERGRPSLYV 351 I ++R ++ + DL + R++ + + R + KL ER R S+ Sbjct: 199 INNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSER-RKSIKT 257 Query: 352 QRDIVQETQREEDHRREGLHVGRASTPDWVSEGP-QPGLRRALSSDSILS----PAPDAR 406 R+IVQE +R E E R+ +EG Q + R S+++L P R Sbjct: 258 YREIVQEKERRERELHEAYKNARSQEE---AEGILQQYIERFTISEAVLERLEMPKILER 314 Query: 407 AADPAPEVRKVNRIP-PDAYQPYLSPGTPQLEFSAFGAFGKPSSLSTAEAKAATSPKATM 465 + P + P P Y S P+ + + S L T+ + + SP T+ Sbjct: 315 SHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTV 374 Query: 466 SPRHLSESSGKPLSTKQEASKPPRGCPQANRGVVRWEYFRLRPLRFRAPDEPQQAQVPHV 525 +P+ + + KP S + + + + V E +E ++ + P V Sbjct: 375 TPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVH--------REEEKERECPTV 426 Query: 526 WGWEVAGAPALRLQKSQSSDLLERERESVLRREQ-----EVAEERRNALFPEVFSPT--- 577 APA L KSQ + + R S L +Q E+ ++ N++ E+ + T Sbjct: 427 -------APAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKT 479 Query: 578 -PDENSDQNSRSSSQASGI 595 P+ D+N S+ I Sbjct: 480 EPNSQEDKNDGGKSRKGNI 498 >gi|163310745 LIM and calponin homology domains 1 isoform c [Homo sapiens] Length = 1056 Score = 37.7 bits (86), Expect = 0.035 Identities = 70/319 (21%), Positives = 124/319 (38%), Gaps = 35/319 (10%) Query: 293 IEREIRLAQER-EADLREQRGLRQATDHQELVEIPTRPLLTKLSLITAPRRERGRPSLYV 351 I ++R ++ + DL + R++ + + R + KL ER R S+ Sbjct: 353 INNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSER-RKSIKT 411 Query: 352 QRDIVQETQREEDHRREGLHVGRASTPDWVSEGP-QPGLRRALSSDSILS----PAPDAR 406 R+IVQE +R E E R+ +EG Q + R S+++L P R Sbjct: 412 YREIVQEKERRERELHEAYKNARSQEE---AEGILQQYIERFTISEAVLERLEMPKILER 468 Query: 407 AADPAPEVRKVNRIP-PDAYQPYLSPGTPQLEFSAFGAFGKPSSLSTAEAKAATSPKATM 465 + P + P P Y S P+ + + S L T+ + + SP T+ Sbjct: 469 SHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTV 528 Query: 466 SPRHLSESSGKPLSTKQEASKPPRGCPQANRGVVRWEYFRLRPLRFRAPDEPQQAQVPHV 525 +P+ + + KP S + + + + V E +E ++ + P V Sbjct: 529 TPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVH--------REEEKERECPTV 580 Query: 526 WGWEVAGAPALRLQKSQSSDLLERERESVLRREQ-----EVAEERRNALFPEVFSPT--- 577 APA L KSQ + + R S L +Q E+ ++ N++ E+ + T Sbjct: 581 -------APAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKT 633 Query: 578 -PDENSDQNSRSSSQASGI 595 P+ D+N S+ I Sbjct: 634 EPNSQEDKNDGGKSRKGNI 652 >gi|163310743 LIM and calponin homology domains 1 isoform b [Homo sapiens] Length = 1057 Score = 37.7 bits (86), Expect = 0.035 Identities = 70/319 (21%), Positives = 124/319 (38%), Gaps = 35/319 (10%) Query: 293 IEREIRLAQER-EADLREQRGLRQATDHQELVEIPTRPLLTKLSLITAPRRERGRPSLYV 351 I ++R ++ + DL + R++ + + R + KL ER R S+ Sbjct: 353 INNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSER-RKSIKT 411 Query: 352 QRDIVQETQREEDHRREGLHVGRASTPDWVSEGP-QPGLRRALSSDSILS----PAPDAR 406 R+IVQE +R E E R+ +EG Q + R S+++L P R Sbjct: 412 YREIVQEKERRERELHEAYKNARSQEE---AEGILQQYIERFTISEAVLERLEMPKILER 468 Query: 407 AADPAPEVRKVNRIP-PDAYQPYLSPGTPQLEFSAFGAFGKPSSLSTAEAKAATSPKATM 465 + P + P P Y S P+ + + S L T+ + + SP T+ Sbjct: 469 SHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTV 528 Query: 466 SPRHLSESSGKPLSTKQEASKPPRGCPQANRGVVRWEYFRLRPLRFRAPDEPQQAQVPHV 525 +P+ + + KP S + + + + V E +E ++ + P V Sbjct: 529 TPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVH--------REEEKERECPTV 580 Query: 526 WGWEVAGAPALRLQKSQSSDLLERERESVLRREQ-----EVAEERRNALFPEVFSPT--- 577 APA L KSQ + + R S L +Q E+ ++ N++ E+ + T Sbjct: 581 -------APAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKT 633 Query: 578 -PDENSDQNSRSSSQASGI 595 P+ D+N S+ I Sbjct: 634 EPNSQEDKNDGGKSRKGNI 652 >gi|163310741 LIM and calponin homology domains 1 isoform a [Homo sapiens] Length = 1083 Score = 37.7 bits (86), Expect = 0.035 Identities = 70/319 (21%), Positives = 124/319 (38%), Gaps = 35/319 (10%) Query: 293 IEREIRLAQER-EADLREQRGLRQATDHQELVEIPTRPLLTKLSLITAPRRERGRPSLYV 351 I ++R ++ + DL + R++ + + R + KL ER R S+ Sbjct: 353 INNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSER-RKSIKT 411 Query: 352 QRDIVQETQREEDHRREGLHVGRASTPDWVSEGP-QPGLRRALSSDSILS----PAPDAR 406 R+IVQE +R E E R+ +EG Q + R S+++L P R Sbjct: 412 YREIVQEKERRERELHEAYKNARSQEE---AEGILQQYIERFTISEAVLERLEMPKILER 468 Query: 407 AADPAPEVRKVNRIP-PDAYQPYLSPGTPQLEFSAFGAFGKPSSLSTAEAKAATSPKATM 465 + P + P P Y S P+ + + S L T+ + + SP T+ Sbjct: 469 SHSTEPNLSSFLNDPNPMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTV 528 Query: 466 SPRHLSESSGKPLSTKQEASKPPRGCPQANRGVVRWEYFRLRPLRFRAPDEPQQAQVPHV 525 +P+ + + KP S + + + + V E +E ++ + P V Sbjct: 529 TPKAVPMLTPKPYSQPKNSQDVLKTFKVDGKVSVNGETVH--------REEEKERECPTV 580 Query: 526 WGWEVAGAPALRLQKSQSSDLLERERESVLRREQ-----EVAEERRNALFPEVFSPT--- 577 APA L KSQ + + R S L +Q E+ ++ N++ E+ + T Sbjct: 581 -------APAHSLTKSQMFEGVARVHGSPLELKQDNGSIEINIKKPNSVPQELAATTEKT 633 Query: 578 -PDENSDQNSRSSSQASGI 595 P+ D+N S+ I Sbjct: 634 EPNSQEDKNDGGKSRKGNI 652 >gi|221139926 NHS-like 1 [Homo sapiens] Length = 1606 Score = 37.4 bits (85), Expect = 0.046 Identities = 54/219 (24%), Positives = 77/219 (35%), Gaps = 45/219 (20%) Query: 376 STPDWVSEGPQPGLRRALSSDSILSPAPDARAADPAPEVRKVNRIPPDAYQPYLSPGTPQ 435 S PDW P+P L L PD+ + P P + PP A P L P + Sbjct: 984 SPPDWCLSPPRPALSPIL---------PDSPVSLPLPPPLLPSSEPPPA--PPLDPKFMK 1032 Query: 436 LEFSAFGAFGKPSSLSTAEAKAATSPKATMSPRHLSESSGKPLSTKQEASKPPRGCPQAN 495 F G+P S S S +P STK+E S+PP P Sbjct: 1033 DTRPPFTNSGQPES---------------------SRGSLRPPSTKEETSRPP--MPLIT 1069 Query: 496 RGVVRWEYFRLRPLRFRAPDEPQQAQVPHVWGWEVAGAPALRLQKSQSSDLLERERESVL 555 + + +LRP+R + E Q AP L+ S+ L R + + Sbjct: 1070 TEAL--QMVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLK--PSAFLKSRNSTNEM 1125 Query: 556 RREQEVAEERRNALFPEVFSPTPDENSDQNSRSSSQASG 594 E + A + PTP ++S Q S+ G Sbjct: 1126 ESESQPASVTSSL-------PTPAKSSSQGDHGSAAERG 1157 >gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] Length = 3957 Score = 37.0 bits (84), Expect = 0.060 Identities = 50/227 (22%), Positives = 86/227 (37%), Gaps = 21/227 (9%) Query: 274 DDPGSLASVESPGTPKETPIEREIRLAQEREAD----LREQRGLRQATDHQELVEIP--- 326 D+ S P + P+ R+++ Q+++ + E+ L++ + + L E P Sbjct: 1685 DETQSTQKQHKPSLGIKKPVRRKLKEKQKQKEEGLQASAEKAELKKGSSEESLGEDPGLA 1744 Query: 327 TRPLLTKLSLITAPR-RERGRPSLYVQRDIVQETQREEDHRREGLHV---GRASTPDWVS 382 PL T + T+P E S+ + +Q+ +E R L + G+ P + Sbjct: 1745 PEPLPTVKA--TSPLIEETPIGSIKDKVKALQKRVEDEQKGRSKLPIRVKGKEDVPKKTT 1802 Query: 383 EGPQPGLRRALSSDSIL--SPAPDARAADPAPEVRKVNRIPPDAYQPYLSPGTPQLEFSA 440 P P +L S+ SP+P K R PP +SP + + S Sbjct: 1803 HRPHPAASPSLKSERHAPGSPSPKTERHSTLSSSAKTERHPP------VSPSSKTEKHSP 1856 Query: 441 FGAFGKPSSLSTAEAKAATSPKATMSPRHLSESSGKPLSTKQEASKP 487 K S A + + T + +SP +E STK E P Sbjct: 1857 VSPSAKTERHSPASSSSKTEKHSPVSPSTKTERHSPVSSTKTERHPP 1903 >gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Homo sapiens] Length = 1751 Score = 36.6 bits (83), Expect = 0.078 Identities = 24/87 (27%), Positives = 36/87 (41%), Gaps = 3/87 (3%) Query: 207 NKGAPHSSPARGTPAGTTPGASQAPKAFNKPHL-ANGHVVPIKPQVKGVVREENKVRAVP 265 ++G P S A T AGT P + +P + +P G VP P G + + P Sbjct: 171 SRGIPSSPGAHTTEAGTLPAPTPSPPSLGRPWAPLTGPSVP--PPSSGRASLSSLLGGAP 228 Query: 266 TWASVQVVDDPGSLASVESPGTPKETP 292 W S+Q D G + +P + P Sbjct: 229 PWGSLQDPDSQGLSPAAAAPSQQLQRP 255 >gi|51464815 PREDICTED: similar to hCG1745223 [Homo sapiens] Length = 319 Score = 36.2 bits (82), Expect = 0.10 Identities = 30/126 (23%), Positives = 49/126 (38%), Gaps = 12/126 (9%) Query: 115 DGEDKEMKTYRLDAGDADPRRLCDLERERWAVIQG-------QAVRKSSTVATLQGTPDH 167 D + K ++ L + P C + RW Q R+ + + P + Sbjct: 114 DAKLKGVRMSTLQTAETKPTPTCPRRQRRWLRTTPHPPPPTRQGSREMAGAFLVAPRPPY 173 Query: 168 GDPRTPGPPRSTPLEENVVD---REQIDFLAARQQFLSLEQANKGAPHSSPARGTPAGTT 224 R+PG P S P +V+ R + D L+A +++Q P PA+ G Sbjct: 174 S--RSPGGPESAPTPASVLPELRRGKQDLLSADSGLPAVDQGEVAGPRLQPAQPLRPGAV 231 Query: 225 PGASQA 230 P AS+A Sbjct: 232 PSASRA 237 >gi|225735627 disco-interacting protein 2A isoform f [Homo sapiens] Length = 798 Score = 35.8 bits (81), Expect = 0.13 Identities = 36/161 (22%), Positives = 60/161 (37%), Gaps = 5/161 (3%) Query: 135 RLCDLERERWAVIQGQAVRKSSTVATLQGTPDHGDPRTPGPPRSTPLEENVVDREQIDFL 194 R + +R +V+ +V + T + D G R PG STPL+ + +D + Sbjct: 111 RKMPMPSKRRSVLVHSSVETYTPPDTSSASEDEGSLRRPGRLTSTPLQSHSSVEPWLDRV 170 Query: 195 AARQQFLSLEQANKGAPHSSPARGTPAGTTPGASQAPKAFNKPHLANGHV-VPIKPQVKG 253 S + P P A TPGA+ A+ H+ VP+ +V Sbjct: 171 IQGSSTSSSASSTSSHPGGRPTTAPSAAATPGAAATTALAGLE--AHTHIGVPVNSRVSS 228 Query: 254 VVREENKVRAVPTWASVQ--VVDDPGSLASVESPGTPKETP 292 +++ P ++ VDD L V+ P + P Sbjct: 229 KIQQLLNTLKRPKRPPLKEFFVDDFEELLEVQQPDPNQPKP 269 >gi|41281612 zinc finger protein 828 [Homo sapiens] Length = 812 Score = 35.8 bits (81), Expect = 0.13 Identities = 42/156 (26%), Positives = 58/156 (37%), Gaps = 15/156 (9%) Query: 385 PQPGLRRALSSDSILSPAPDAR----AADPAPEVRKVNRIPPDAYQPYLSPGTPQLEFSA 440 P+P ++SS P A P+PE +K + P++ + LS PQ + Sbjct: 174 PEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHF 233 Query: 441 FGAFGKPSSLSTAEAKAATSPKA-TMSPRHLSESSGKPLSTKQEASKP-PRGCPQANRGV 498 G PS+ S A SP+ SP ES +T E KP P P+ Sbjct: 234 PETLGPPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEP---- 289 Query: 499 VRWEYFRLRPLRFRAPDEPQQAQVPHVWGWEVAGAP 534 W+ F P P P A P W G+P Sbjct: 290 --WKPF---PAVSPEPRRPAPAVSPGSWKPGPPGSP 320 Score = 30.0 bits (66), Expect = 7.3 Identities = 63/281 (22%), Positives = 106/281 (37%), Gaps = 43/281 (15%) Query: 373 GRASTPDWVSEGPQPGLRRALSSDSILSPAPDARAADPA----PEVRKVNR-IPPDAYQP 427 G +P+ S P LR+ S + +PD R PA PE +K +R PD ++ Sbjct: 423 GPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKS 482 Query: 428 --YLSPGTPQLEFSAFGAFGKPSSLSTAEAKAATSP--KATMSPRHLSESSGKPLSTKQE 483 ++ P P F KP +E+ A S K +S + KP + Sbjct: 483 SFFIEPQKP-----VFPETRKPGPSGPSESPKAASDIWKPVLS---IDTEPRKPALFPEP 534 Query: 484 ASKPPRGCPQANRGVVRWEYFRLRPLRFRAPDEPQQAQVPHVWGWEVAGAPALRLQKSQS 543 A P P+A + + F P+ P+ A A+ L Sbjct: 535 AKTAPPASPEARKRAL----FPEPRKHALFPELPKSALFSE-------SQKAVELGDELQ 583 Query: 544 SDLLERERESVLRREQEVAEERR---NALFPEVFSPTPD--ENSDQNSRSSS------QA 592 D ++ ++ +L +E+ +A ++ + LFP D E+SD SS A Sbjct: 584 IDAIDDQKCDILVQEELLASPKKLLEDTLFPSSKKLKKDNQESSDAELSSSEYIKTDLDA 643 Query: 593 SGITGSYSVSESPFFSPIHLHSNVAWTVEDPVDSAPPGQRK 633 I G S S+ + + S + ++ E+ +D P Q + Sbjct: 644 MDIKGQESSSDQ---EQVDVES-IDFSKENKMDMTSPEQSR 680 >gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens] Length = 953 Score = 35.8 bits (81), Expect = 0.13 Identities = 48/190 (25%), Positives = 75/190 (39%), Gaps = 20/190 (10%) Query: 316 ATDHQELVEIPTRPLLTKLSLITAPRRERGRPSLYVQRDIVQETQREEDHRRE------- 368 + D +++ P+ + S AP + R + D V+E +R+ D + Sbjct: 725 SVDSEDMYADLASPVSSASSRSPAPAQTRKEKGKSKKEDGVKEEKRKRDSSTQPPKSAKP 784 Query: 369 ---GLHVGRASTPDWVSEG-PQPGLRRALSSD--SILSPAPDARAADPAPEVRKVNRIPP 422 G + STP G PQ G A ++L+ A D + K + PP Sbjct: 785 PAGGKSSQQPSTPQQAPPGQPQQGTFVAHKEIKLTLLNKAADKGSRKRYEPSDKDRQSPP 844 Query: 423 DAYQPYLSPGTPQLEFSAFGAFG--KPSSLSTAEAKAATSP---KATMSPRHLSESSGKP 477 A +P SP + + G G KP +KA +P K +SP+ S+SS K Sbjct: 845 PAKRPNTSPDRGSRDRKSGGRLGSPKPERQRGQNSKAPAAPADRKRQLSPQ--SKSSSKV 902 Query: 478 LSTKQEASKP 487 S +AS P Sbjct: 903 TSVPGKASDP 912 >gi|118600967 shroom family member 4 [Homo sapiens] Length = 1493 Score = 35.4 bits (80), Expect = 0.17 Identities = 44/177 (24%), Positives = 64/177 (36%), Gaps = 48/177 (27%) Query: 472 ESSGKPLSTKQEASKPPRGCPQANRGVVRWEYFRLRPLRFRAPDEPQQAQVPHVWGWEVA 531 E+ L +++A PPR P WE +RL FRA + +Q Q Sbjct: 1086 ETQSDLLGARKKAFPPPRPPPP------NWEKYRL----FRAAQQQKQQQQQQ------- 1128 Query: 532 GAPALRLQKSQSSDLLERERESVLRREQEVAEERRNALFPEVFSP--------TPDENSD 583 ++ + + E E E E+E AEE L P+ FS P+E + Sbjct: 1129 -------KQQEEEEEEEEEEEEEEEEEEEEAEEEEEELPPQYFSSETSGSCALNPEEVLE 1181 Query: 584 Q----------NSRSSSQA-SGITGSYSVSESPFFSPIHLHSNVAWTVEDPVDSAPP 629 Q SR SQ+ S+++ S F PI H P + PP Sbjct: 1182 QPQPLSFGHLEGSRQGSQSVPAEQESFALHSSDFLPPIRGHLG-----SQPEQAQPP 1233 >gi|110349719 titin isoform N2-A [Homo sapiens] Length = 33423 Score = 35.4 bits (80), Expect = 0.17 Identities = 76/344 (22%), Positives = 122/344 (35%), Gaps = 69/344 (20%) Query: 250 QVKGVVREENKVRAVPTWASVQVVDDPGSLASVESPGTPKETPIEREIRLAQEREADLRE 309 QV+ V EE+ R VP A V P ++ P K IE+ R +E + + + Sbjct: 9151 QVQKEVYEESHERKVP--AKVPEKKAPPPPKVIKKPVIEK---IEKTSRRMEEEKVQVTK 9205 Query: 310 ----------QRGLRQATDHQELVEIPTRPLLTKLSLITAPRRERGRPSLYVQRDIVQET 359 Q+ R +E++E+ + TK +I+ + + V E Sbjct: 9206 VPEVSKKIVPQKPSRTPVQ-EEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPEV 9264 Query: 360 QREEDHRREGLHVG---RASTPDWVSEGPQPGLRRALSSDSILSPAPDARAADPAPEVRK 416 Q+E E +HV R P V E P+ PAP+ A P P+ Sbjct: 9265 QKEIV-TEEKIHVAISKRVEPPPKVPELPE-------------KPAPEEVAPVPIPK--- 9307 Query: 417 VNRIPPDAYQPYLSPGTPQLEFSAFGAFGKPSSLSTAEAKAATSPKATMSPRHLSESSGK 476 ++ P A P P++ KP + E A PK P+ Sbjct: 9308 --KVEPPA------PKVPEVPKKPVPEEKKPVPVPKKEP--AAPPKVPEVPKKPVPEEKI 9357 Query: 477 PLSTKQEASKPPRGCPQANRGVVRWEYFRLRPLRFRAPDEPQQAQVPHVWGWEVAGAPAL 536 P+ ++ PP P+ +GVV E + R +P P ++P Sbjct: 9358 PVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESP-PPAVPEIP------------- 9403 Query: 537 RLQKSQSSDLLERERESVLRREQEVAEERRNALFPEVFSPTPDE 580 + ER+ V R+E+EV + P+ P P+E Sbjct: 9404 -------KKKVPEERKPVPRKEEEVPPPPKVPALPK--KPVPEE 9438 Score = 30.4 bits (67), Expect = 5.6 Identities = 73/367 (19%), Positives = 121/367 (32%), Gaps = 38/367 (10%) Query: 220 PAGTTPGASQAPKAFNKPHLANGHVVPIKPQVKGVVREENKVRAVPTWASVQVVDDPGSL 279 P P P P VV KP++ V E VP VV Sbjct: 10685 PEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEA 10744 Query: 280 ASVESPGTPKETPIEREIRLAQEREADLREQRGLRQATDHQELVEIPTRPLLTKLSLITA 339 + P PKE E+++ + ++ E ++ E+P +P+L + + Sbjct: 10745 PPAKVPEVPKEVVPEKKVAVPKKPE------------VPPAKVPEVPKKPVLEEKPAVPV 10792 Query: 340 PRR-ERGRPSLYVQRDIVQETQREEDHRREGLHVGRASTPDWVSEGPQPGLRRALSSDSI 398 P R E P +Y + + + + + + V P+ V P + + + Sbjct: 10793 PERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPE-VPPPAVPEEPKKIIPEKK 10851 Query: 399 LSPAPDARAADP-APEVRKVNRIPPDAYQPYLSPGTPQLEFSAFGAFGKPSSLSTAEAKA 457 + A P PE KV P +P P P E F + KA Sbjct: 10852 VPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIF---------QLKA 10902 Query: 458 ATSPKATMSPRHLSESSGKPLST----KQEASKPPRGCPQANRGVVRWEYFRLRPLRFRA 513 K P+ + PL K+ P P+ VV R RP Sbjct: 10903 IPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEP 10962 Query: 514 PDEPQQAQVPHVWGWEVAGAPALRLQKSQSSDLLERERESVLRREQEVAEERR-NALFPE 572 EP++ E PA+ + + E E +V +RE+++ E + + P Sbjct: 10963 KVEPKKL--------EKVKKPAVP-EPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPA 11013 Query: 573 VFSPTPD 579 + P P+ Sbjct: 11014 IPLPAPE 11020 >gi|22547204 hairless protein isoform a [Homo sapiens] Length = 1189 Score = 35.4 bits (80), Expect = 0.17 Identities = 54/189 (28%), Positives = 72/189 (38%), Gaps = 19/189 (10%) Query: 343 ERGRPSLYVQRDIVQETQREEDHRREGLHVGRASTPDWVS-EGPQPGLRRALSS------ 395 E RPSL+ QRD R+++ L +G+ T W S PGL L + Sbjct: 242 EAERPSLH-QRDGEMGAGRQQNPCP--LFLGQPDTVPWTSWPACPPGLVHTLGNVWAGPG 298 Query: 396 DSILSP--APDARAADPAPEVRKVNRIPPDAYQPYLSPGTPQLEFSAFGAFGKPSSLS-- 451 D L P A P+PE R +Y P G G G S S Sbjct: 299 DGNLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTKGGGLGPCGKCQEGLEGGASGASEP 358 Query: 452 TAEAKAATSPKATMSPRHLSESSGKPLSTKQEASKPPRGCPQANRGVVRWEYFRLRPLRF 511 + E A+ P+A P H ++ L+ E + PRGCP+ V RLR L+ Sbjct: 359 SEEVNKASGPRAC-PPSHHTKLKKTWLTRHSEQFECPRGCPEVEERPVA----RLRALKR 413 Query: 512 RAPDEPQQA 520 E Q A Sbjct: 414 AGSPEVQGA 422 >gi|22547207 hairless protein isoform b [Homo sapiens] Length = 1134 Score = 35.4 bits (80), Expect = 0.17 Identities = 54/189 (28%), Positives = 72/189 (38%), Gaps = 19/189 (10%) Query: 343 ERGRPSLYVQRDIVQETQREEDHRREGLHVGRASTPDWVS-EGPQPGLRRALSS------ 395 E RPSL+ QRD R+++ L +G+ T W S PGL L + Sbjct: 242 EAERPSLH-QRDGEMGAGRQQNPCP--LFLGQPDTVPWTSWPACPPGLVHTLGNVWAGPG 298 Query: 396 DSILSP--APDARAADPAPEVRKVNRIPPDAYQPYLSPGTPQLEFSAFGAFGKPSSLS-- 451 D L P A P+PE R +Y P G G G S S Sbjct: 299 DGNLGYQLGPPATPRCPSPEPPVTQRGCCSSYPPTKGGGLGPCGKCQEGLEGGASGASEP 358 Query: 452 TAEAKAATSPKATMSPRHLSESSGKPLSTKQEASKPPRGCPQANRGVVRWEYFRLRPLRF 511 + E A+ P+A P H ++ L+ E + PRGCP+ V RLR L+ Sbjct: 359 SEEVNKASGPRAC-PPSHHTKLKKTWLTRHSEQFECPRGCPEVEERPVA----RLRALKR 413 Query: 512 RAPDEPQQA 520 E Q A Sbjct: 414 AGSPEVQGA 422 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.130 0.389 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 31,561,810 Number of Sequences: 37866 Number of extensions: 1737989 Number of successful extensions: 6531 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 25 Number of HSP's successfully gapped in prelim test: 193 Number of HSP's that attempted gapping in prelim test: 6231 Number of HSP's gapped (non-prelim): 525 length of query: 679 length of database: 18,247,518 effective HSP length: 109 effective length of query: 570 effective length of database: 14,120,124 effective search space: 8048470680 effective search space used: 8048470680 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.