Guide to the Human Genome
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Search of human proteins with 27436893

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27436893 tapasin isoform 1 precursor [Homo sapiens]
         (448 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27436893 tapasin isoform 1 precursor [Homo sapiens]                917   0.0  
gi|27436897 tapasin isoform 3 precursor [Homo sapiens]                833   0.0  
gi|27436895 tapasin isoform 2 precursor [Homo sapiens]                595   e-170
gi|157739930 TAP binding protein-like [Homo sapiens]                   77   2e-14
gi|112790163 metal-regulatory transcription factor 1 [Homo sapiens]    41   0.002
gi|155030211 major histocompatibility complex, class II, DR beta...    40   0.004
gi|239748820 PREDICTED: hypothetical protein XP_002346811 [Homo ...    39   0.007
gi|239740859 PREDICTED: similar to major histocompatibility comp...    39   0.007
gi|239740857 PREDICTED: similar to major histocompatibility comp...    39   0.007
gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]            39   0.007
gi|38569493 potassium voltage-gated channel, subfamily H (eag-re...    39   0.012
gi|239752152 PREDICTED: hypothetical protein XP_002348153 [Homo ...    38   0.021
gi|17986005 major histocompatibility complex, class II, DR beta ...    37   0.047
gi|239758092 PREDICTED: similar to HLA class II histocompatibili...    37   0.047
gi|239748785 PREDICTED: similar to HLA class II histocompatibili...    37   0.047
gi|239740745 PREDICTED: similar to HLA class II histocompatibili...    37   0.047
gi|239740743 PREDICTED: similar to HLA class II histocompatibili...    37   0.047
gi|239740695 PREDICTED: similar to HLA class II histocompatibili...    37   0.047
gi|239740693 PREDICTED: similar to HLA class II histocompatibili...    37   0.047
gi|239740855 PREDICTED: similar to major histocompatibility comp...    36   0.062
gi|239740853 PREDICTED: similar to major histocompatibility comp...    36   0.062
gi|239748415 PREDICTED: hypothetical protein [Homo sapiens]            36   0.081
gi|239742343 PREDICTED: hypothetical protein XP_002342497 [Homo ...    36   0.081
gi|24797076 major histocompatibility complex, class II, DP beta ...    35   0.11 
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom...    35   0.14 
gi|239753856 PREDICTED: hypothetical protein [Homo sapiens]            35   0.14 
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom...    35   0.14 
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap...    35   0.14 
gi|52630344 major histocompatibility complex, class II, DR beta ...    35   0.18 
gi|239758090 PREDICTED: major histocompatibility complex, class ...    35   0.18 

>gi|27436893 tapasin isoform 1 precursor [Homo sapiens]
          Length = 448

 Score =  917 bits (2369), Expect = 0.0
 Identities = 448/448 (100%), Positives = 448/448 (100%)

Query: 1   MKSLSLLLAVALGLATAVSAGPAVIECWFVEDASGKGLAKRPGALLLRQGPGEPPPRPDL 60
           MKSLSLLLAVALGLATAVSAGPAVIECWFVEDASGKGLAKRPGALLLRQGPGEPPPRPDL
Sbjct: 1   MKSLSLLLAVALGLATAVSAGPAVIECWFVEDASGKGLAKRPGALLLRQGPGEPPPRPDL 60

Query: 61  DPELYLSVHDPAGALQAAFRRYPRGAPAPHCEMSRFVPLPASAKWASGLTPAQNCPRALD 120
           DPELYLSVHDPAGALQAAFRRYPRGAPAPHCEMSRFVPLPASAKWASGLTPAQNCPRALD
Sbjct: 61  DPELYLSVHDPAGALQAAFRRYPRGAPAPHCEMSRFVPLPASAKWASGLTPAQNCPRALD 120

Query: 121 GAWLMVSISSPVLSLSSLLRPQPEPQQEPVLITMATVVLTVLTHTPAPRVRLGQDALLDL 180
           GAWLMVSISSPVLSLSSLLRPQPEPQQEPVLITMATVVLTVLTHTPAPRVRLGQDALLDL
Sbjct: 121 GAWLMVSISSPVLSLSSLLRPQPEPQQEPVLITMATVVLTVLTHTPAPRVRLGQDALLDL 180

Query: 181 SFAYMPPTSEAASSLAPGPPPFGLEWRRQHLGKGHLLLAATPGLNGQMPAAQEGAVAFAA 240
           SFAYMPPTSEAASSLAPGPPPFGLEWRRQHLGKGHLLLAATPGLNGQMPAAQEGAVAFAA
Sbjct: 181 SFAYMPPTSEAASSLAPGPPPFGLEWRRQHLGKGHLLLAATPGLNGQMPAAQEGAVAFAA 240

Query: 241 WDDDEPWGPWTGNGTFWLPTVQPFQEGTYLATIHLPYLQGQVTLELAVYKPPKVSLMPAT 300
           WDDDEPWGPWTGNGTFWLPTVQPFQEGTYLATIHLPYLQGQVTLELAVYKPPKVSLMPAT
Sbjct: 241 WDDDEPWGPWTGNGTFWLPTVQPFQEGTYLATIHLPYLQGQVTLELAVYKPPKVSLMPAT 300

Query: 301 LARAAPGEAPPELLCLVSHFYPSGGLEVEWELRGGPGGRSQKAEGQRWLSALRHHSDGSV 360
           LARAAPGEAPPELLCLVSHFYPSGGLEVEWELRGGPGGRSQKAEGQRWLSALRHHSDGSV
Sbjct: 301 LARAAPGEAPPELLCLVSHFYPSGGLEVEWELRGGPGGRSQKAEGQRWLSALRHHSDGSV 360

Query: 361 SLSGHLQPPPVTTEQHGARYACRIHHPSLPASGRSAEVTLEVAGLSGPSLEDSVGLFLSA 420
           SLSGHLQPPPVTTEQHGARYACRIHHPSLPASGRSAEVTLEVAGLSGPSLEDSVGLFLSA
Sbjct: 361 SLSGHLQPPPVTTEQHGARYACRIHHPSLPASGRSAEVTLEVAGLSGPSLEDSVGLFLSA 420

Query: 421 FLLLGLFKALGWAAVYLSTCKDSKKKAE 448
           FLLLGLFKALGWAAVYLSTCKDSKKKAE
Sbjct: 421 FLLLGLFKALGWAAVYLSTCKDSKKKAE 448


>gi|27436897 tapasin isoform 3 precursor [Homo sapiens]
          Length = 412

 Score =  833 bits (2151), Expect = 0.0
 Identities = 405/406 (99%), Positives = 405/406 (99%)

Query: 1   MKSLSLLLAVALGLATAVSAGPAVIECWFVEDASGKGLAKRPGALLLRQGPGEPPPRPDL 60
           MKSLSLLLAVALGLATAVSAGPAVIECWFVEDASGKGLAKRPGALLLRQGPGEPPPRPDL
Sbjct: 1   MKSLSLLLAVALGLATAVSAGPAVIECWFVEDASGKGLAKRPGALLLRQGPGEPPPRPDL 60

Query: 61  DPELYLSVHDPAGALQAAFRRYPRGAPAPHCEMSRFVPLPASAKWASGLTPAQNCPRALD 120
           DPELYLSVHDPAGALQAAFRRYPRGAPAPHCEMSRFVPLPASAKWASGLTPAQNCPRALD
Sbjct: 61  DPELYLSVHDPAGALQAAFRRYPRGAPAPHCEMSRFVPLPASAKWASGLTPAQNCPRALD 120

Query: 121 GAWLMVSISSPVLSLSSLLRPQPEPQQEPVLITMATVVLTVLTHTPAPRVRLGQDALLDL 180
           GAWLMVSISSPVLSLSSLLRPQPEPQQEPVLITMATVVLTVLTHTPAPRVRLGQDALLDL
Sbjct: 121 GAWLMVSISSPVLSLSSLLRPQPEPQQEPVLITMATVVLTVLTHTPAPRVRLGQDALLDL 180

Query: 181 SFAYMPPTSEAASSLAPGPPPFGLEWRRQHLGKGHLLLAATPGLNGQMPAAQEGAVAFAA 240
           SFAYMPPTSEAASSLAPGPPPFGLEWRRQHLGKGHLLLAATPGLNGQMPAAQEGAVAFAA
Sbjct: 181 SFAYMPPTSEAASSLAPGPPPFGLEWRRQHLGKGHLLLAATPGLNGQMPAAQEGAVAFAA 240

Query: 241 WDDDEPWGPWTGNGTFWLPTVQPFQEGTYLATIHLPYLQGQVTLELAVYKPPKVSLMPAT 300
           WDDDEPWGPWTGNGTFWLPTVQPFQEGTYLATIHLPYLQGQVTLELAVYKPPKVSLMPAT
Sbjct: 241 WDDDEPWGPWTGNGTFWLPTVQPFQEGTYLATIHLPYLQGQVTLELAVYKPPKVSLMPAT 300

Query: 301 LARAAPGEAPPELLCLVSHFYPSGGLEVEWELRGGPGGRSQKAEGQRWLSALRHHSDGSV 360
           LARAAPGEAPPELLCLVSHFYPSGGLEVEWELRGGPGGRSQKAEGQRWLSALRHHSDGSV
Sbjct: 301 LARAAPGEAPPELLCLVSHFYPSGGLEVEWELRGGPGGRSQKAEGQRWLSALRHHSDGSV 360

Query: 361 SLSGHLQPPPVTTEQHGARYACRIHHPSLPASGRSAEVTLEVAGLS 406
           SLSGHLQPPPVTTEQHGARYACRIHHPSLPASGRSAEVTLEVAG S
Sbjct: 361 SLSGHLQPPPVTTEQHGARYACRIHHPSLPASGRSAEVTLEVAGKS 406


>gi|27436895 tapasin isoform 2 precursor [Homo sapiens]
          Length = 299

 Score =  595 bits (1533), Expect = e-170
 Identities = 289/289 (100%), Positives = 289/289 (100%)

Query: 1   MKSLSLLLAVALGLATAVSAGPAVIECWFVEDASGKGLAKRPGALLLRQGPGEPPPRPDL 60
           MKSLSLLLAVALGLATAVSAGPAVIECWFVEDASGKGLAKRPGALLLRQGPGEPPPRPDL
Sbjct: 1   MKSLSLLLAVALGLATAVSAGPAVIECWFVEDASGKGLAKRPGALLLRQGPGEPPPRPDL 60

Query: 61  DPELYLSVHDPAGALQAAFRRYPRGAPAPHCEMSRFVPLPASAKWASGLTPAQNCPRALD 120
           DPELYLSVHDPAGALQAAFRRYPRGAPAPHCEMSRFVPLPASAKWASGLTPAQNCPRALD
Sbjct: 61  DPELYLSVHDPAGALQAAFRRYPRGAPAPHCEMSRFVPLPASAKWASGLTPAQNCPRALD 120

Query: 121 GAWLMVSISSPVLSLSSLLRPQPEPQQEPVLITMATVVLTVLTHTPAPRVRLGQDALLDL 180
           GAWLMVSISSPVLSLSSLLRPQPEPQQEPVLITMATVVLTVLTHTPAPRVRLGQDALLDL
Sbjct: 121 GAWLMVSISSPVLSLSSLLRPQPEPQQEPVLITMATVVLTVLTHTPAPRVRLGQDALLDL 180

Query: 181 SFAYMPPTSEAASSLAPGPPPFGLEWRRQHLGKGHLLLAATPGLNGQMPAAQEGAVAFAA 240
           SFAYMPPTSEAASSLAPGPPPFGLEWRRQHLGKGHLLLAATPGLNGQMPAAQEGAVAFAA
Sbjct: 181 SFAYMPPTSEAASSLAPGPPPFGLEWRRQHLGKGHLLLAATPGLNGQMPAAQEGAVAFAA 240

Query: 241 WDDDEPWGPWTGNGTFWLPTVQPFQEGTYLATIHLPYLQGQVTLELAVY 289
           WDDDEPWGPWTGNGTFWLPTVQPFQEGTYLATIHLPYLQGQVTLELAVY
Sbjct: 241 WDDDEPWGPWTGNGTFWLPTVQPFQEGTYLATIHLPYLQGQVTLELAVY 289


>gi|157739930 TAP binding protein-like [Homo sapiens]
          Length = 468

 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 117/453 (25%), Positives = 174/453 (38%), Gaps = 67/453 (14%)

Query: 6   LLLAVALGLATAVSAGPA---------VIECWFVEDASGKGLA-----KRPGALLLRQGP 51
           LLL +AL  A      PA         V++C+  +D + +G       +   +L+L+Q P
Sbjct: 9   LLLCLALSGAAETKPHPAEGQWRAVDVVLDCFLAKDGAHRGALASSEDRARASLVLKQVP 68

Query: 52  ----GEPPPRPDLDPELYLSVHDPAGALQAAFR--RYPRGAPAPH---------CEMSRF 96
               G      D      L+  DP    +A+    + P+     H         CE+SR+
Sbjct: 69  VLDDGSLEDFTDFQGGT-LAQDDPPIIFEASVDLVQIPQAEALLHADCSGKEVTCEISRY 127

Query: 97  VPLPASAKWASGLTPAQNCPRALDGAWLMVSISSP-VLSLSSLLRPQPEPQQEPVLITMA 155
                     +      N   +  G  + + + +P V    +L  P       P      
Sbjct: 128 FLQMTETTVKTAAWFMANMQVSGGGPSISLVMKTPRVTKNEALWHPTLNLPLSPQGTVRT 187

Query: 156 TVVLTVLTHTPAPRVRLGQDALLDLSFAYMPPTSEAASSLAPGPPPFGLEWRRQHLGKGH 215
            V   V+T T +    LG  A LD  F           S+APG     +EWR QH G+G 
Sbjct: 188 AVEFQVMTQTQSLSFLLGSSASLDCGF-----------SMAPGLDLISVEWRLQHKGRGQ 236

Query: 216 LLLAATPGLNGQMPAAQEGAVAFAAWDDDEPWGPWTGNGTFWLPTVQPFQEGTYLATIHL 275
           L+ + T    GQ  A ++GA    A            + +  LP +    EGTY+  I  
Sbjct: 237 LVYSWTA---GQGQAVRKGATLEPAQLG------MARDASLTLPGLTIQDEGTYICQITT 287

Query: 276 PYLQGQVTLELAVYKPPKVSLMPATLARAAPGEAPPELLCLVSHFYPSGGLEVEWELRGG 335
              + Q  ++L +   PKV L  A  A        P L+C ++ +YP   + V W  R  
Sbjct: 288 SLYRAQQIIQLNIQASPKVRLSLANEALL------PTLICDIAGYYPL-DVVVTW-TREE 339

Query: 336 PGGRSQKAEGQRWLSALRHHSDGSVSLSGHLQPPPVTTEQHGARYACRIHHPSL--PASG 393
            GG   +  G  + S+LR    G+ S+S  L   P +    GA Y C++ H SL  P   
Sbjct: 340 LGGSPAQVSGASF-SSLRQSVAGTYSISSSLTAEPGSA---GATYTCQVTHISLEEPLGA 395

Query: 394 RSAEVTLEVAGLSGPSLEDSVGLFLSAFLLLGL 426
            +  V  E     G     S  LFL A + LGL
Sbjct: 396 STQVVPPERRTALGVIFASS--LFLLALMFLGL 426


>gi|112790163 metal-regulatory transcription factor 1 [Homo sapiens]
          Length = 753

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 43/157 (27%), Positives = 66/157 (42%), Gaps = 31/157 (19%)

Query: 37  GLAKRPGALLLRQGPGEPPPRPDLDPELYLSVHDPAGALQAAFRRYPRGAPAPHCEMSRF 96
           GL++ P  LL    P  PPP P L P          G+ QAAF   P     P       
Sbjct: 426 GLSEPPQPLLPASAPSAPPPAPSLGP----------GSQQAAFGNPPALLQPPE------ 469

Query: 97  VPLPASAKWASG---LTPAQNCPRAL-DGAWLMVSISSPVLSLSSLLRPQPEPQQ--EPV 150
           VP+P S ++A+      P    P+ +  G  ++   S+   +++S +     PQ   EP+
Sbjct: 470 VPVPHSTQFAANHQEFLPHPQAPQPIVPGLSVVAGASASAAAVASAVAAPAPPQSTTEPL 529

Query: 151 LITMATV------VLT---VLTHTPAPRVRLGQDALL 178
              + T+      VLT    +T TP P   + Q +L+
Sbjct: 530 PAMVQTLPLGANSVLTNNPTITITPTPNTAILQSSLV 566


>gi|155030211 major histocompatibility complex, class II, DR beta 1
           precursor [Homo sapiens]
          Length = 266

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 40/138 (28%), Positives = 60/138 (43%), Gaps = 24/138 (17%)

Query: 292 PKVSLMPATLARAAPGEAPPELLCLVSHFYPSGGLEVEWELRGGPGGRSQKAEGQRWLSA 351
           PKV++ P+   +  P +    L+C VS FYP G +EV W L G      Q+ +     + 
Sbjct: 126 PKVTVYPS---KTQPLQHHNLLVCSVSGFYP-GSIEVRWFLNG------QEEKAGMVSTG 175

Query: 352 LRHHSDGSVSLSGHLQPPPVTTEQHGARYACRIHHPS----LPASGRSAEVTLEVAGLSG 407
           L  + D +      L+  P    + G  Y C++ HPS    L    R+   + +   LSG
Sbjct: 176 LIQNGDWTFQTLVMLETVP----RSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSG 231

Query: 408 PSLEDSVGLFLSAFLLLG 425
                 VG F+   L LG
Sbjct: 232 ------VGGFVLGLLFLG 243


>gi|239748820 PREDICTED: hypothetical protein XP_002346811 [Homo
           sapiens]
          Length = 266

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 40/138 (28%), Positives = 60/138 (43%), Gaps = 24/138 (17%)

Query: 292 PKVSLMPATLARAAPGEAPPELLCLVSHFYPSGGLEVEWELRGGPGGRSQKAEGQRWLSA 351
           PKV++ P+   +  P +    L+C VS FYP G +EV W   G      Q+ +     + 
Sbjct: 126 PKVTVYPS---KTQPLQHHNLLVCSVSGFYP-GSIEVRWFRNG------QEEKTGVVSTG 175

Query: 352 LRHHSDGSVSLSGHLQPPPVTTEQHGARYACRIHHPS----LPASGRSAEVTLEVAGLSG 407
           L H+ D +      L+  P    + G  Y C++ HPS    L    R+   + +   LSG
Sbjct: 176 LIHNGDWTFQTLVMLETVP----RSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSG 231

Query: 408 PSLEDSVGLFLSAFLLLG 425
                 VG F+   L LG
Sbjct: 232 ------VGGFVLGLLFLG 243


>gi|239740859 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 1 [Homo sapiens]
          Length = 267

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 40/138 (28%), Positives = 60/138 (43%), Gaps = 24/138 (17%)

Query: 292 PKVSLMPATLARAAPGEAPPELLCLVSHFYPSGGLEVEWELRGGPGGRSQKAEGQRWLSA 351
           PKV++ P+   +  P +    L+C VS FYP G +EV W   G      Q+ +     + 
Sbjct: 127 PKVTVYPS---KTQPLQHHNLLVCSVSGFYP-GSIEVRWFRNG------QEEKTGVVSTG 176

Query: 352 LRHHSDGSVSLSGHLQPPPVTTEQHGARYACRIHHPS----LPASGRSAEVTLEVAGLSG 407
           L H+ D +      L+  P    + G  Y C++ HPS    L    R+   + +   LSG
Sbjct: 177 LIHNGDWTFQTLVMLETVP----RSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSG 232

Query: 408 PSLEDSVGLFLSAFLLLG 425
                 VG F+   L LG
Sbjct: 233 ------VGGFVLGLLFLG 244


>gi|239740857 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 2 [Homo sapiens]
          Length = 266

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 40/138 (28%), Positives = 60/138 (43%), Gaps = 24/138 (17%)

Query: 292 PKVSLMPATLARAAPGEAPPELLCLVSHFYPSGGLEVEWELRGGPGGRSQKAEGQRWLSA 351
           PKV++ P+   +  P +    L+C VS FYP G +EV W   G      Q+ +     + 
Sbjct: 126 PKVTVYPS---KTQPLQHHNLLVCSVSGFYP-GSIEVRWFRNG------QEEKTGVVSTG 175

Query: 352 LRHHSDGSVSLSGHLQPPPVTTEQHGARYACRIHHPS----LPASGRSAEVTLEVAGLSG 407
           L H+ D +      L+  P    + G  Y C++ HPS    L    R+   + +   LSG
Sbjct: 176 LIHNGDWTFQTLVMLETVP----RSGEVYTCQVEHPSVTSPLTVEWRARSESAQSKMLSG 231

Query: 408 PSLEDSVGLFLSAFLLLG 425
                 VG F+   L LG
Sbjct: 232 ------VGGFVLGLLFLG 243


>gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]
          Length = 980

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 57/241 (23%), Positives = 88/241 (36%), Gaps = 44/241 (18%)

Query: 3   SLSLLLAVALGLATAVSAG----PAVIECWFVEDASGKGLAKRPGALLLRQGPGEPPPRP 58
           S +LL  +ALG    V A     P  +    +  + G GL  R G LL+R+G   P P P
Sbjct: 77  SRALLRLLALGSGAWVRARAVRRPPALGWALLGTSLGPGLGPRVGPLLVRRGETLPVPGP 136

Query: 59  D-----------LDPELYLSVHDPAGALQAAFRRYPRGAPAPHCEMSRFVPLPASAKWAS 107
                       L P   L+V +  G  +          P P   +S F  +  + +   
Sbjct: 137 RVLETRPALQGLLGPGTRLAVTELRGRARLCPESGDSSRPPPPPVVSSFA-VSGTVRRLQ 195

Query: 108 G--------LTPAQNCPRAL---DGAWLMVS-----------------ISSPVLSLSSLL 139
           G        L  +++C R L    G W+ V+                 +  P   LS  L
Sbjct: 196 GVLGGTGDSLGVSRSCLRGLGLFQGEWVWVAQARESSNTSQPHLARVQVLEPRWDLSDRL 255

Query: 140 RPQPEPQQEPVLITMATVVLTVLTHTPAPRVRLGQDALLDLSFAYMPPTSEAASSLAPGP 199
            P   P  EP+   +A V  T+  +     + +G+  +       + P  + + SL PGP
Sbjct: 256 GPGSGPLGEPLADGLALVPATLAFNLGCDPLEMGELRIQRYLEGSIAPEDKGSCSLLPGP 315

Query: 200 P 200
           P
Sbjct: 316 P 316


>gi|38569493 potassium voltage-gated channel, subfamily H
           (eag-related), member 3 [Homo sapiens]
          Length = 1083

 Score = 38.5 bits (88), Expect = 0.012
 Identities = 52/204 (25%), Positives = 64/204 (31%), Gaps = 41/204 (20%)

Query: 35  GKGLAKRPGALLLRQGPGEPPPR--------------PDLDPELYLSVHDPAGALQAAFR 80
           G+G   R GAL    GP  PP                PDL P +   + D  G+ Q  F 
Sbjct: 781 GRGRPGRAGALKAEAGPSAPPRALEGLRLPPMPWNVPPDLSPRVVDGIEDGCGSDQPKF- 839

Query: 81  RYPRGAPAPHCEMSRFVPLPASAKWASGLTPAQNCPRALDGAWLMVSISSPVLSLSSLLR 140
            +  G   P C  S   P P      SGL    + P        +  +   V  LS  + 
Sbjct: 840 SFRVGQSGPECSSS---PSPGP---ESGLLTVPHGPSEARNTDTLDKLRQAVTELSEQVL 893

Query: 141 PQPEPQQEPVLITMATVVLTVLTHTPAPRVR-----------LGQDALLDL---SFAYMP 186
              E  Q   L     +VL      P PR             L Q   +D    S+   P
Sbjct: 894 QMREGLQS--LRQAVQLVLAPHREGPCPRASGEGPCPASTSGLLQPLCVDTGASSYCLQP 951

Query: 187 PTSEAASSL----APGPPPFGLEW 206
           P     S       PGPPP    W
Sbjct: 952 PAGSVLSGTWPHPRPGPPPLMAPW 975


>gi|239752152 PREDICTED: hypothetical protein XP_002348153 [Homo
           sapiens]
          Length = 264

 Score = 37.7 bits (86), Expect = 0.021
 Identities = 61/256 (23%), Positives = 89/256 (34%), Gaps = 55/256 (21%)

Query: 149 PVLITMATVVL-----TVLTHTPAPRVRLGQDALLDLS-------------FAYMPPTSE 190
           P+L+T+ T        +VLT  P+     GQ   +  S             +  +P T+ 
Sbjct: 31  PLLLTLLTHCAGSWAQSVLTQPPSASGTPGQRVTISCSGSSSNIGSNTVNWYQQLPGTAP 90

Query: 191 AASSLAPGPPPFGLEWRRQHLGKGHLLLAATPGLNGQMPAAQEGAVAFAAWDDDEPWGPW 250
                +    P G+  R      G     A  GL  +     E     AAWDD       
Sbjct: 91  KLLIYSNNQRPSGVPDRFSGSKSGTSASLAISGLQSE----DEADYYCAAWDDSL----- 141

Query: 251 TGNGTFWLPTVQPFQEGTYLATIHLPYLQGQVTLELAVYKPPKVSLMPATLARAAPGEAP 310
             NG    PT   F  GT L  +  P     VTL      PP    + A  A        
Sbjct: 142 --NG----PTCWVFGGGTKLTVLGQPKAAPSVTLF-----PPSSEELQANKAT------- 183

Query: 311 PELLCLVSHFYPSGGLEVEWELRGGPGGRSQKAEGQRWLSALRHHSDGSVSLSGHLQPPP 370
             L+CL+S FYP G + V W+    P     +       +     S+   + S +L   P
Sbjct: 184 --LVCLISDFYP-GAVTVAWKADSSPVKAGVET------TTPSKQSNNKYAASSYLSLTP 234

Query: 371 VTTEQHGARYACRIHH 386
              + H + Y+C++ H
Sbjct: 235 EQWKSHRS-YSCQVTH 249


>gi|17986005 major histocompatibility complex, class II, DR beta 3
           precursor [Homo sapiens]
          Length = 266

 Score = 36.6 bits (83), Expect = 0.047
 Identities = 39/138 (28%), Positives = 59/138 (42%), Gaps = 24/138 (17%)

Query: 292 PKVSLMPATLARAAPGEAPPELLCLVSHFYPSGGLEVEWELRGGPGGRSQKAEGQRWLSA 351
           P+V++ PA   +  P +    L+C VS FYP G +EV W   G      Q+ +     + 
Sbjct: 126 PQVTVYPA---KTQPLQHHNLLVCSVSGFYP-GSIEVRWFRNG------QEEKAGVVSTG 175

Query: 352 LRHHSDGSVSLSGHLQPPPVTTEQHGARYACRIHHPS----LPASGRSAEVTLEVAGLSG 407
           L  + D +      L+  P    + G  Y C++ HPS    L    R+   + +   LSG
Sbjct: 176 LIQNGDWTFQTLVMLETVP----RSGEVYTCQVEHPSVTSALTVEWRARSESAQSKMLSG 231

Query: 408 PSLEDSVGLFLSAFLLLG 425
                 VG F+   L LG
Sbjct: 232 ------VGGFVLGLLFLG 243


>gi|239758092 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain [Homo sapiens]
          Length = 253

 Score = 36.6 bits (83), Expect = 0.047
 Identities = 39/138 (28%), Positives = 59/138 (42%), Gaps = 24/138 (17%)

Query: 292 PKVSLMPATLARAAPGEAPPELLCLVSHFYPSGGLEVEWELRGGPGGRSQKAEGQRWLSA 351
           P+V++ PA   +  P +    L+C VS FYP G +EV W   G      Q+ +     + 
Sbjct: 113 PEVTVYPA---KTQPLQHHNLLVCSVSGFYP-GSIEVRWFRNG------QEEKAGVVSTG 162

Query: 352 LRHHSDGSVSLSGHLQPPPVTTEQHGARYACRIHHPS----LPASGRSAEVTLEVAGLSG 407
           L  + D +      L+  P    + G  Y C++ HPS    L    R+   + +   LSG
Sbjct: 163 LIQNGDWTFQTLVMLETVP----RSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSG 218

Query: 408 PSLEDSVGLFLSAFLLLG 425
                 VG F+   L LG
Sbjct: 219 ------VGGFVLGLLFLG 230


>gi|239748785 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-9 beta chain [Homo sapiens]
          Length = 266

 Score = 36.6 bits (83), Expect = 0.047
 Identities = 39/138 (28%), Positives = 59/138 (42%), Gaps = 24/138 (17%)

Query: 292 PKVSLMPATLARAAPGEAPPELLCLVSHFYPSGGLEVEWELRGGPGGRSQKAEGQRWLSA 351
           P+V++ PA   +  P +    L+C VS FYP G +EV W   G      Q+ +     + 
Sbjct: 126 PEVTVYPA---KTQPLQHHNLLVCSVSGFYP-GSIEVRWFRNG------QEEKAGVVSTG 175

Query: 352 LRHHSDGSVSLSGHLQPPPVTTEQHGARYACRIHHPS----LPASGRSAEVTLEVAGLSG 407
           L  + D +      L+  P    + G  Y C++ HPS    L    R+   + +   LSG
Sbjct: 176 LIQNGDWTFQTLVMLETVP----RSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSG 231

Query: 408 PSLEDSVGLFLSAFLLLG 425
                 VG F+   L LG
Sbjct: 232 ------VGGFVLGLLFLG 243


>gi|239740745 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain isoform 1 [Homo sapiens]
          Length = 266

 Score = 36.6 bits (83), Expect = 0.047
 Identities = 39/138 (28%), Positives = 59/138 (42%), Gaps = 24/138 (17%)

Query: 292 PKVSLMPATLARAAPGEAPPELLCLVSHFYPSGGLEVEWELRGGPGGRSQKAEGQRWLSA 351
           P+V++ PA   +  P +    L+C VS FYP G +EV W   G      Q+ +     + 
Sbjct: 126 PEVTVYPA---KTQPLQHHNLLVCSVSGFYP-GSIEVRWFRNG------QEEKAGVVSTG 175

Query: 352 LRHHSDGSVSLSGHLQPPPVTTEQHGARYACRIHHPS----LPASGRSAEVTLEVAGLSG 407
           L  + D +      L+  P    + G  Y C++ HPS    L    R+   + +   LSG
Sbjct: 176 LIQNGDWTFQTLVMLETVP----RSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSG 231

Query: 408 PSLEDSVGLFLSAFLLLG 425
                 VG F+   L LG
Sbjct: 232 ------VGGFVLGLLFLG 243


>gi|239740743 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain isoform 2 [Homo sapiens]
          Length = 264

 Score = 36.6 bits (83), Expect = 0.047
 Identities = 39/138 (28%), Positives = 59/138 (42%), Gaps = 24/138 (17%)

Query: 292 PKVSLMPATLARAAPGEAPPELLCLVSHFYPSGGLEVEWELRGGPGGRSQKAEGQRWLSA 351
           P+V++ PA   +  P +    L+C VS FYP G +EV W   G      Q+ +     + 
Sbjct: 124 PEVTVYPA---KTQPLQHHNLLVCSVSGFYP-GSIEVRWFRNG------QEEKAGVVSTG 173

Query: 352 LRHHSDGSVSLSGHLQPPPVTTEQHGARYACRIHHPS----LPASGRSAEVTLEVAGLSG 407
           L  + D +      L+  P    + G  Y C++ HPS    L    R+   + +   LSG
Sbjct: 174 LIQNGDWTFQTLVMLETVP----RSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSG 229

Query: 408 PSLEDSVGLFLSAFLLLG 425
                 VG F+   L LG
Sbjct: 230 ------VGGFVLGLLFLG 241


>gi|239740695 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain isoform 1 [Homo sapiens]
          Length = 266

 Score = 36.6 bits (83), Expect = 0.047
 Identities = 39/138 (28%), Positives = 59/138 (42%), Gaps = 24/138 (17%)

Query: 292 PKVSLMPATLARAAPGEAPPELLCLVSHFYPSGGLEVEWELRGGPGGRSQKAEGQRWLSA 351
           P+V++ PA   +  P +    L+C VS FYP G +EV W   G      Q+ +     + 
Sbjct: 126 PEVTVYPA---KTQPLQHHNLLVCSVSGFYP-GSIEVRWFRNG------QEEKAGVVSTG 175

Query: 352 LRHHSDGSVSLSGHLQPPPVTTEQHGARYACRIHHPS----LPASGRSAEVTLEVAGLSG 407
           L  + D +      L+  P    + G  Y C++ HPS    L    R+   + +   LSG
Sbjct: 176 LIQNGDWTFQTLVMLETVP----RSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSG 231

Query: 408 PSLEDSVGLFLSAFLLLG 425
                 VG F+   L LG
Sbjct: 232 ------VGGFVLGLLFLG 243


>gi|239740693 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-7 beta chain isoform 2 [Homo sapiens]
          Length = 264

 Score = 36.6 bits (83), Expect = 0.047
 Identities = 39/138 (28%), Positives = 59/138 (42%), Gaps = 24/138 (17%)

Query: 292 PKVSLMPATLARAAPGEAPPELLCLVSHFYPSGGLEVEWELRGGPGGRSQKAEGQRWLSA 351
           P+V++ PA   +  P +    L+C VS FYP G +EV W   G      Q+ +     + 
Sbjct: 124 PEVTVYPA---KTQPLQHHNLLVCSVSGFYP-GSIEVRWFRNG------QEEKAGVVSTG 173

Query: 352 LRHHSDGSVSLSGHLQPPPVTTEQHGARYACRIHHPS----LPASGRSAEVTLEVAGLSG 407
           L  + D +      L+  P    + G  Y C++ HPS    L    R+   + +   LSG
Sbjct: 174 LIQNGDWTFQTLVMLETVP----RSGEVYTCQVEHPSVMSPLTVEWRARSESAQSKMLSG 229

Query: 408 PSLEDSVGLFLSAFLLLG 425
                 VG F+   L LG
Sbjct: 230 ------VGGFVLGLLFLG 241


>gi|239740855 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 1 [Homo sapiens]
          Length = 267

 Score = 36.2 bits (82), Expect = 0.062
 Identities = 37/137 (27%), Positives = 62/137 (45%), Gaps = 22/137 (16%)

Query: 292 PKVSLMPATLARAAPGEAPPELLCLVSHFYPSGGLEVEWELRGGPGGRSQKAEGQRWLSA 351
           P+V++ PA   +  P +    L+C VS FYP G +EV W   G      Q+ +     + 
Sbjct: 127 PQVTVYPA---KTQPLQHHNLLVCSVSGFYP-GSIEVRWFRNG------QEEKAGVVSTG 176

Query: 352 LRHHSDGSVSLSGHLQPPPVTTEQHGARYACRIHHPSLPASGRSAEVTLEVAGLSGPS-- 409
           L  + D +      L+  P    + G  Y C++ HPS+     ++ +T+E +  S  +  
Sbjct: 177 LIQNGDWTFQTLVMLETVP----RSGEVYTCQVEHPSV-----TSPLTVEWSARSESAQS 227

Query: 410 -LEDSVGLFLSAFLLLG 425
            +   VG F+   L LG
Sbjct: 228 KMLSGVGGFVLGLLFLG 244


>gi|239740853 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 2 [Homo sapiens]
          Length = 266

 Score = 36.2 bits (82), Expect = 0.062
 Identities = 37/137 (27%), Positives = 62/137 (45%), Gaps = 22/137 (16%)

Query: 292 PKVSLMPATLARAAPGEAPPELLCLVSHFYPSGGLEVEWELRGGPGGRSQKAEGQRWLSA 351
           P+V++ PA   +  P +    L+C VS FYP G +EV W   G      Q+ +     + 
Sbjct: 126 PQVTVYPA---KTQPLQHHNLLVCSVSGFYP-GSIEVRWFRNG------QEEKAGVVSTG 175

Query: 352 LRHHSDGSVSLSGHLQPPPVTTEQHGARYACRIHHPSLPASGRSAEVTLEVAGLSGPS-- 409
           L  + D +      L+  P    + G  Y C++ HPS+     ++ +T+E +  S  +  
Sbjct: 176 LIQNGDWTFQTLVMLETVP----RSGEVYTCQVEHPSV-----TSPLTVEWSARSESAQS 226

Query: 410 -LEDSVGLFLSAFLLLG 425
            +   VG F+   L LG
Sbjct: 227 KMLSGVGGFVLGLLFLG 243


>gi|239748415 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 208

 Score = 35.8 bits (81), Expect = 0.081
 Identities = 25/70 (35%), Positives = 38/70 (54%), Gaps = 7/70 (10%)

Query: 39  AKRPGALLLRQGPGEPPPRPDLDPELYLSVHDPAG-ALQAA---FRRYPRGAPAPHCEMS 94
           A R G   + +G  E PP P L PEL   + +P+G A+Q++   FRR P     P  +++
Sbjct: 67  ADREGEREVLRGQRESPPPPQLPPEL---LTNPSGSAIQSSPSRFRRVPADNAGPRRQLA 123

Query: 95  RFVPLPASAK 104
           + VPL   A+
Sbjct: 124 KGVPLRPGAE 133


>gi|239742343 PREDICTED: hypothetical protein XP_002342497 [Homo
           sapiens]
          Length = 208

 Score = 35.8 bits (81), Expect = 0.081
 Identities = 25/70 (35%), Positives = 38/70 (54%), Gaps = 7/70 (10%)

Query: 39  AKRPGALLLRQGPGEPPPRPDLDPELYLSVHDPAG-ALQAA---FRRYPRGAPAPHCEMS 94
           A R G   + +G  E PP P L PEL   + +P+G A+Q++   FRR P     P  +++
Sbjct: 67  ADREGEREVLRGQRESPPPPQLPPEL---LTNPSGSAIQSSPSRFRRVPADNAGPRRQLA 123

Query: 95  RFVPLPASAK 104
           + VPL   A+
Sbjct: 124 KGVPLRPGAE 133


>gi|24797076 major histocompatibility complex, class II, DP beta 1
           precursor [Homo sapiens]
          Length = 258

 Score = 35.4 bits (80), Expect = 0.11
 Identities = 32/112 (28%), Positives = 54/112 (48%), Gaps = 16/112 (14%)

Query: 278 LQGQVTLELAVYKPPKVSLMPATLARAAPGEAPPELLCLVSHFYPSGGLEVEWELRGGPG 337
           L G +TL+  V   P+V++ P+   +  P +    L+C V+ FYP G ++V W L G   
Sbjct: 112 LGGPMTLQRRVQ--PRVNVSPS---KKGPLQHHNLLVCHVTDFYP-GSIQVRWFLNG--- 162

Query: 338 GRSQKAEGQRWLSALRHHSDGSVSLSGHLQPPPVTTEQHGARYACRIHHPSL 389
              ++  G    + +R+  D +  +   L+  P    Q G  Y C++ H SL
Sbjct: 163 --QEETAGVVSTNLIRN-GDWTFQILVMLEMTP----QQGDVYTCQVEHTSL 207


>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
           sapiens]
          Length = 1188

 Score = 35.0 bits (79), Expect = 0.14
 Identities = 96/422 (22%), Positives = 135/422 (31%), Gaps = 71/422 (16%)

Query: 42  PGALLLRQGPGEPPPRPDLDPEL------YLSVHDPAGALQAAFRRYPRGAPAPHCEMSR 95
           P   L    P  PPP P L P          + H PAG  +      P   P P+     
Sbjct: 392 PAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPE 451

Query: 96  FVPLPASAKWASGLTPAQNCPRALDGAWLMVSISSPVLSLSSLLRPQPEPQQE-----PV 150
                A   W     P+Q      + A  +         LS    P   PQ +     P 
Sbjct: 452 NTASSAPVDWRD---PSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPR 508

Query: 151 LITMATVVLTVLTHTP--APRVRLGQDALLDLSFAYMPPTSEAASSLAPGPPPFGLEWRR 208
           L    T++      TP   P   LG  +L +   A  P  +  +    P   P     + 
Sbjct: 509 LPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAA--PSLTLPSVDYIPQDSPTPSVRQI 566

Query: 209 QHLGKGHLLLAATP------GLNGQMPAAQEGAVAFAAWDDDEPWGPWTGNGTFWLPTVQ 262
           ++  +  L  AA        G     P  + G +     DDD+   P   N         
Sbjct: 567 RNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKN--------L 618

Query: 263 PFQEGTYLATIHL-------PYLQGQVTLELAVYKPPKVSLMPATLARAAPGEAPP---- 311
           P Q  T L T  L       P +  + T E A+  PPK +L PAT  +A  G A P    
Sbjct: 619 PPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAI--PPKATLWPATPPKATLGPATPLKAT 676

Query: 312 ------------ELLCLVSHFYPSGGLEVEWELRGGPGGRSQKAEGQRWLSALRHHSDGS 359
                         +   +   P+   ++  E   GP G+ +K   Q   +  +   +GS
Sbjct: 677 SGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGS 736

Query: 360 VSLSGHLQPP--------PVTTEQHGARYACRIHHPSLPASGRSAEV-----TLEVAGLS 406
            S +  L           P  T   G    C ++ P    S  S EV     TL   G +
Sbjct: 737 PSEATRLPTQGARSSAAFPPKTSPGGGEVPC-LYKPHCHQSSLSREVAVVMPTLARGGAA 795

Query: 407 GP 408
           GP
Sbjct: 796 GP 797


>gi|239753856 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 208

 Score = 35.0 bits (79), Expect = 0.14
 Identities = 25/70 (35%), Positives = 37/70 (52%), Gaps = 7/70 (10%)

Query: 39  AKRPGALLLRQGPGEPPPRPDLDPELYLSVHDPAG-ALQAA---FRRYPRGAPAPHCEMS 94
           A R G   + +G  E PP P L PEL   + +P+G A+Q++   FRR P     P  ++ 
Sbjct: 67  ADREGEREVLRGQRESPPPPQLPPEL---LTNPSGSAIQSSPSRFRRVPADNAGPRRQLP 123

Query: 95  RFVPLPASAK 104
           + VPL   A+
Sbjct: 124 KGVPLRPGAE 133


>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
           sapiens]
          Length = 1188

 Score = 35.0 bits (79), Expect = 0.14
 Identities = 96/422 (22%), Positives = 135/422 (31%), Gaps = 71/422 (16%)

Query: 42  PGALLLRQGPGEPPPRPDLDPEL------YLSVHDPAGALQAAFRRYPRGAPAPHCEMSR 95
           P   L    P  PPP P L P          + H PAG  +      P   P P+     
Sbjct: 392 PAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPE 451

Query: 96  FVPLPASAKWASGLTPAQNCPRALDGAWLMVSISSPVLSLSSLLRPQPEPQQE-----PV 150
                A   W     P+Q      + A  +         LS    P   PQ +     P 
Sbjct: 452 NTASSAPVDWRD---PSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPR 508

Query: 151 LITMATVVLTVLTHTP--APRVRLGQDALLDLSFAYMPPTSEAASSLAPGPPPFGLEWRR 208
           L    T++      TP   P   LG  +L +   A  P  +  +    P   P     + 
Sbjct: 509 LPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAA--PSLTLPSVDYIPQDSPTPSVRQI 566

Query: 209 QHLGKGHLLLAATP------GLNGQMPAAQEGAVAFAAWDDDEPWGPWTGNGTFWLPTVQ 262
           ++  +  L  AA        G     P  + G +     DDD+   P   N         
Sbjct: 567 RNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKN--------L 618

Query: 263 PFQEGTYLATIHL-------PYLQGQVTLELAVYKPPKVSLMPATLARAAPGEAPP---- 311
           P Q  T L T  L       P +  + T E A+  PPK +L PAT  +A  G A P    
Sbjct: 619 PPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAI--PPKATLWPATPPKATLGPATPLKAT 676

Query: 312 ------------ELLCLVSHFYPSGGLEVEWELRGGPGGRSQKAEGQRWLSALRHHSDGS 359
                         +   +   P+   ++  E   GP G+ +K   Q   +  +   +GS
Sbjct: 677 SGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGS 736

Query: 360 VSLSGHLQPP--------PVTTEQHGARYACRIHHPSLPASGRSAEV-----TLEVAGLS 406
            S +  L           P  T   G    C ++ P    S  S EV     TL   G +
Sbjct: 737 PSEATRLPTQGARSSAAFPPKTSPGGGEVPC-LYKPHCHQSSLSREVAVVMPTLARGGAA 795

Query: 407 GP 408
           GP
Sbjct: 796 GP 797


>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
           sapiens]
          Length = 1188

 Score = 35.0 bits (79), Expect = 0.14
 Identities = 96/422 (22%), Positives = 135/422 (31%), Gaps = 71/422 (16%)

Query: 42  PGALLLRQGPGEPPPRPDLDPEL------YLSVHDPAGALQAAFRRYPRGAPAPHCEMSR 95
           P   L    P  PPP P L P          + H PAG  +      P   P P+     
Sbjct: 392 PAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPE 451

Query: 96  FVPLPASAKWASGLTPAQNCPRALDGAWLMVSISSPVLSLSSLLRPQPEPQQE-----PV 150
                A   W     P+Q      + A  +         LS    P   PQ +     P 
Sbjct: 452 NTASSAPVDWRD---PSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPR 508

Query: 151 LITMATVVLTVLTHTP--APRVRLGQDALLDLSFAYMPPTSEAASSLAPGPPPFGLEWRR 208
           L    T++      TP   P   LG  +L +   A  P  +  +    P   P     + 
Sbjct: 509 LPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAA--PSLTLPSVDYIPQDSPTPSVRQI 566

Query: 209 QHLGKGHLLLAATP------GLNGQMPAAQEGAVAFAAWDDDEPWGPWTGNGTFWLPTVQ 262
           ++  +  L  AA        G     P  + G +     DDD+   P   N         
Sbjct: 567 RNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKN--------L 618

Query: 263 PFQEGTYLATIHL-------PYLQGQVTLELAVYKPPKVSLMPATLARAAPGEAPP---- 311
           P Q  T L T  L       P +  + T E A+  PPK +L PAT  +A  G A P    
Sbjct: 619 PPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAI--PPKATLWPATPPKATLGPATPLKAT 676

Query: 312 ------------ELLCLVSHFYPSGGLEVEWELRGGPGGRSQKAEGQRWLSALRHHSDGS 359
                         +   +   P+   ++  E   GP G+ +K   Q   +  +   +GS
Sbjct: 677 SGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGS 736

Query: 360 VSLSGHLQPP--------PVTTEQHGARYACRIHHPSLPASGRSAEV-----TLEVAGLS 406
            S +  L           P  T   G    C ++ P    S  S EV     TL   G +
Sbjct: 737 PSEATRLPTQGARSSAAFPPKTSPGGGEVPC-LYKPHCHQSSLSREVAVVMPTLARGGAA 795

Query: 407 GP 408
           GP
Sbjct: 796 GP 797


>gi|52630344 major histocompatibility complex, class II, DR beta 4
           precursor [Homo sapiens]
          Length = 266

 Score = 34.7 bits (78), Expect = 0.18
 Identities = 39/140 (27%), Positives = 61/140 (43%), Gaps = 28/140 (20%)

Query: 292 PKVSLMPATLARAAPGEAPPELLCLVSHFYPSGGLEVEWELRGGPGGRSQKAEGQRWLSA 351
           PKV++ P+   +  P +    L+C V+ FYP G +EV W   G      Q+ +     + 
Sbjct: 126 PKVTVYPS---KTQPLQHHNLLVCSVNGFYP-GSIEVRWFRNG------QEEKAGVVSTG 175

Query: 352 LRHHSDGSVSLSGHLQPPPVTTEQHGARYACRIHHPSLPA------SGRSAEVTLEVAGL 405
           L  + D +      L+  P    + G  Y C++ HPS+ +      S RS     ++  L
Sbjct: 176 LIQNGDWTFQTLVMLETVP----RSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKM--L 229

Query: 406 SGPSLEDSVGLFLSAFLLLG 425
           SG      VG F+   L LG
Sbjct: 230 SG------VGGFVLGLLFLG 243


>gi|239758090 PREDICTED: major histocompatibility complex, class II,
           DR beta 4 [Homo sapiens]
          Length = 278

 Score = 34.7 bits (78), Expect = 0.18
 Identities = 39/140 (27%), Positives = 61/140 (43%), Gaps = 28/140 (20%)

Query: 292 PKVSLMPATLARAAPGEAPPELLCLVSHFYPSGGLEVEWELRGGPGGRSQKAEGQRWLSA 351
           PKV++ P+   +  P +    L+C V+ FYP G +EV W   G      Q+ +     + 
Sbjct: 138 PKVTVYPS---KTQPLQHHNLLVCSVNGFYP-GSIEVRWFRNG------QEEKAGVVSTG 187

Query: 352 LRHHSDGSVSLSGHLQPPPVTTEQHGARYACRIHHPSLPA------SGRSAEVTLEVAGL 405
           L  + D +      L+  P    + G  Y C++ HPS+ +      S RS     ++  L
Sbjct: 188 LIQNGDWTFQTLVMLETVP----RSGEVYTCQVEHPSMMSPLTVQWSARSESAQSKM--L 241

Query: 406 SGPSLEDSVGLFLSAFLLLG 425
           SG      VG F+   L LG
Sbjct: 242 SG------VGGFVLGLLFLG 255


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,658,286
Number of Sequences: 37866
Number of extensions: 1348809
Number of successful extensions: 4925
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 121
Number of HSP's that attempted gapping in prelim test: 4833
Number of HSP's gapped (non-prelim): 216
length of query: 448
length of database: 18,247,518
effective HSP length: 106
effective length of query: 342
effective length of database: 14,233,722
effective search space: 4867932924
effective search space used: 4867932924
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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