Guide to the Human Genome
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Search of human proteins with 27262653

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27262653 ataxin 2 related protein isoform E [Homo sapiens]
         (1044 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27262653 ataxin 2 related protein isoform E [Homo sapiens]        2143   0.0  
gi|27262645 ataxin 2 related protein isoform B [Homo sapiens]        2130   0.0  
gi|27262651 ataxin 2 related protein isoform D [Homo sapiens]        2114   0.0  
gi|27262649 ataxin 2 related protein isoform C [Homo sapiens]        2113   0.0  
gi|27262647 ataxin 2 related protein isoform A [Homo sapiens]        2113   0.0  
gi|171543895 ataxin 2 [Homo sapiens]                                  610   e-174
gi|163965366 nascent polypeptide-associated complex alpha subuni...   106   1e-22
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...   100   1e-20
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    97   1e-19
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    94   5e-19
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    89   2e-17
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          82   3e-15
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          82   3e-15
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          80   1e-14
gi|55750053 atrophin-1 [Homo sapiens]                                  80   1e-14
gi|55750041 atrophin-1 [Homo sapiens]                                  80   1e-14
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     79   2e-14
gi|150170670 piccolo isoform 2 [Homo sapiens]                          79   2e-14
gi|150378539 piccolo isoform 1 [Homo sapiens]                          79   2e-14
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    74   6e-13
gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s...    72   2e-12
gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s...    72   2e-12
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       72   3e-12
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              72   3e-12
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   71   6e-12
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   71   6e-12
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   71   6e-12
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    71   6e-12
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]         70   8e-12
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             69   2e-11

>gi|27262653 ataxin 2 related protein isoform E [Homo sapiens]
          Length = 1044

 Score = 2143 bits (5553), Expect = 0.0
 Identities = 1044/1044 (100%), Positives = 1044/1044 (100%)

Query: 1    MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
            MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG
Sbjct: 1    MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60

Query: 61   PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
            PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN
Sbjct: 61   PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120

Query: 121  SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180
            SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV
Sbjct: 121  SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180

Query: 181  DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240
            DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD
Sbjct: 181  DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240

Query: 241  YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300
            YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA
Sbjct: 241  YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300

Query: 301  REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360
            REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP
Sbjct: 301  REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360

Query: 361  RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420
            RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK
Sbjct: 361  RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420

Query: 421  TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
            TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV
Sbjct: 421  TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480

Query: 481  TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540
            TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF
Sbjct: 481  TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540

Query: 541  QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600
            QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT
Sbjct: 541  QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600

Query: 601  ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660
            ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN
Sbjct: 601  ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660

Query: 661  PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720
            PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG
Sbjct: 661  PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720

Query: 721  PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780
            PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA
Sbjct: 721  PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780

Query: 781  ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
            ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP
Sbjct: 781  ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840

Query: 841  QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
            QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ
Sbjct: 841  QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900

Query: 901  APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960
            APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM
Sbjct: 901  APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960

Query: 961  AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
            AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP
Sbjct: 961  AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020

Query: 1021 YPYIGHPQAPLPPPGELKIVLAAT 1044
            YPYIGHPQAPLPPPGELKIVLAAT
Sbjct: 1021 YPYIGHPQAPLPPPGELKIVLAAT 1044


>gi|27262645 ataxin 2 related protein isoform B [Homo sapiens]
          Length = 1062

 Score = 2130 bits (5520), Expect = 0.0
 Identities = 1043/1062 (98%), Positives = 1043/1062 (98%), Gaps = 18/1062 (1%)

Query: 1    MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
            MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG
Sbjct: 1    MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60

Query: 61   PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
            PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN
Sbjct: 61   PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120

Query: 121  SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180
            SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV
Sbjct: 121  SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180

Query: 181  DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240
            DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD
Sbjct: 181  DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240

Query: 241  YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300
            YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA
Sbjct: 241  YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300

Query: 301  REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360
            REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP
Sbjct: 301  REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360

Query: 361  RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420
            RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK
Sbjct: 361  RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420

Query: 421  TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
            TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV
Sbjct: 421  TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480

Query: 481  TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540
            TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF
Sbjct: 481  TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540

Query: 541  QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600
            QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT
Sbjct: 541  QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600

Query: 601  ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660
            ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN
Sbjct: 601  ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660

Query: 661  PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720
            PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG
Sbjct: 661  PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720

Query: 721  PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780
            PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA
Sbjct: 721  PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780

Query: 781  ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
            ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP
Sbjct: 781  ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840

Query: 841  QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
            QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ
Sbjct: 841  QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900

Query: 901  APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960
            APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM
Sbjct: 901  APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960

Query: 961  AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
            AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP
Sbjct: 961  AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020

Query: 1021 YPYIGHPQA------------------PLPPPGELKIVLAAT 1044
            YPYIGHPQ                   PLPPPGELKIVLAAT
Sbjct: 1021 YPYIGHPQGEQPGQAPGFPGGADDRIPPLPPPGELKIVLAAT 1062


>gi|27262651 ataxin 2 related protein isoform D [Homo sapiens]
          Length = 1044

 Score = 2114 bits (5478), Expect = 0.0
 Identities = 1032/1043 (98%), Positives = 1032/1043 (98%), Gaps = 8/1043 (0%)

Query: 1    MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
            MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG
Sbjct: 1    MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60

Query: 61   PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
            PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN
Sbjct: 61   PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120

Query: 121  SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180
            SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV
Sbjct: 121  SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180

Query: 181  DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240
            DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD
Sbjct: 181  DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240

Query: 241  YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300
            YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA
Sbjct: 241  YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300

Query: 301  REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360
            REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP
Sbjct: 301  REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360

Query: 361  RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420
            RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK
Sbjct: 361  RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420

Query: 421  TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
            TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV
Sbjct: 421  TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480

Query: 481  TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540
            TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF
Sbjct: 481  TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540

Query: 541  QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600
            QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT
Sbjct: 541  QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600

Query: 601  ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660
            ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN
Sbjct: 601  ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660

Query: 661  PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720
            PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG
Sbjct: 661  PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720

Query: 721  PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780
            PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA
Sbjct: 721  PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780

Query: 781  ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
            ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP
Sbjct: 781  ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840

Query: 841  QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
            QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ
Sbjct: 841  QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900

Query: 901  APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960
            APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM
Sbjct: 901  APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960

Query: 961  AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
            AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP
Sbjct: 961  AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020

Query: 1021 YPYIGHPQA--------PLPPPG 1035
            YPYIGHPQ         P  PPG
Sbjct: 1021 YPYIGHPQVQSHPSQQLPFHPPG 1043


>gi|27262649 ataxin 2 related protein isoform C [Homo sapiens]
          Length = 1097

 Score = 2113 bits (5476), Expect = 0.0
 Identities = 1029/1032 (99%), Positives = 1029/1032 (99%)

Query: 1    MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
            MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG
Sbjct: 1    MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60

Query: 61   PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
            PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN
Sbjct: 61   PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120

Query: 121  SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180
            SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV
Sbjct: 121  SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180

Query: 181  DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240
            DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD
Sbjct: 181  DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240

Query: 241  YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300
            YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA
Sbjct: 241  YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300

Query: 301  REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360
            REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP
Sbjct: 301  REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360

Query: 361  RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420
            RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK
Sbjct: 361  RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420

Query: 421  TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
            TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV
Sbjct: 421  TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480

Query: 481  TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540
            TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF
Sbjct: 481  TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540

Query: 541  QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600
            QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT
Sbjct: 541  QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600

Query: 601  ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660
            ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN
Sbjct: 601  ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660

Query: 661  PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720
            PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG
Sbjct: 661  PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720

Query: 721  PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780
            PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA
Sbjct: 721  PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780

Query: 781  ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
            ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP
Sbjct: 781  ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840

Query: 841  QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
            QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ
Sbjct: 841  QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900

Query: 901  APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960
            APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM
Sbjct: 901  APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960

Query: 961  AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
            AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP
Sbjct: 961  AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020

Query: 1021 YPYIGHPQAPLP 1032
            YPYIGHPQ   P
Sbjct: 1021 YPYIGHPQGEQP 1032


>gi|27262647 ataxin 2 related protein isoform A [Homo sapiens]
          Length = 1075

 Score = 2113 bits (5476), Expect = 0.0
 Identities = 1029/1032 (99%), Positives = 1029/1032 (99%)

Query: 1    MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
            MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG
Sbjct: 1    MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60

Query: 61   PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
            PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN
Sbjct: 61   PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120

Query: 121  SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180
            SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV
Sbjct: 121  SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180

Query: 181  DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240
            DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD
Sbjct: 181  DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240

Query: 241  YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300
            YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA
Sbjct: 241  YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300

Query: 301  REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360
            REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP
Sbjct: 301  REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360

Query: 361  RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420
            RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK
Sbjct: 361  RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420

Query: 421  TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
            TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV
Sbjct: 421  TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480

Query: 481  TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540
            TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF
Sbjct: 481  TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540

Query: 541  QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600
            QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT
Sbjct: 541  QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600

Query: 601  ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660
            ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN
Sbjct: 601  ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660

Query: 661  PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720
            PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG
Sbjct: 661  PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720

Query: 721  PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780
            PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA
Sbjct: 721  PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780

Query: 781  ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
            ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP
Sbjct: 781  ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840

Query: 841  QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
            QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ
Sbjct: 841  QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900

Query: 901  APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960
            APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM
Sbjct: 901  APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960

Query: 961  AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
            AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP
Sbjct: 961  AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020

Query: 1021 YPYIGHPQAPLP 1032
            YPYIGHPQ   P
Sbjct: 1021 YPYIGHPQGEQP 1032


>gi|171543895 ataxin 2 [Homo sapiens]
          Length = 1313

 Score =  610 bits (1574), Expect = e-174
 Identities = 455/1196 (38%), Positives = 613/1196 (51%), Gaps = 225/1196 (18%)

Query: 2    LKPQPLQQPSQPQQPPPTQQAVARR--PPGGTSPPNGGLPGPLATSAAPPGPPAAASPCL 59
            LKPQ  QQ  Q QQ    QQ   ++  PP   +    G  G LA+ AA P P  ++S   
Sbjct: 163  LKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSP--SSSSVS 220

Query: 60   GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPV-FEGVY 118
               A A S +     G   P                 G  RG+++ KG PQS + F+G+Y
Sbjct: 221  SSSATAPSSVVAATSGGGRP-----------------GLGRGRNSNKGLPQSTISFDGIY 263

Query: 119  NNSRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRRED 178
             N RM+H LT+VVGS C+V+VKNG  YEG+FKT S K +L +DA H K++E + GP+RE+
Sbjct: 264  ANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREE 323

Query: 179  IVDTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGD--S 236
            I+++++FK SD ++V F+++D +YA +D FTDSAI+  +KVNGEHKEK L+ W+ G+  +
Sbjct: 324  IMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAIS--AKVNGEHKEKDLEPWDAGELTA 381

Query: 237  NSDDYDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRA 296
            N +   LE+D+SNGWDPN+MF++NEENYGV +TYDSSLSSYTVPLE+DNSEEF +RE RA
Sbjct: 382  NEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARA 441

Query: 297  AQLAREIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRV 356
             QLA EIESS QY+ R+A+ENDD R+EEEK++AVQR  S RE  S+ +RE KYIP  QR 
Sbjct: 442  NQLAEEIESSAQYKARVALENDD-RSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQRN 500

Query: 357  REG-PRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGG---PSRM-SPK 411
            RE    G  R +S R G+PG  S+P R   H  + +P  GS+ R +NGG   PS   SP 
Sbjct: 501  REVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPS 560

Query: 412  AQRPLR----------GAKTLSSPSNRPSGETSVPP---------------PPAVGRMYP 446
            ++ P R           A T + P +RP    S PP               P  +    P
Sbjct: 561  SRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGP 620

Query: 447  PR-SPK----------SAAPAPISASCP----EPPIGSAVPTSSASIPVTSSVSD--PGV 489
            PR SPK          SA    IS+        PP  +A P  + + P   + S    GV
Sbjct: 621  PRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGV 680

Query: 490  GSISP----------------------ASPKISLAPTDVKELSTKEPGRTLEPQELARIA 527
              +SP                      ASP+  + PT+   ++   P  +  P   A   
Sbjct: 681  PRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEA--VAMPIPAASPTPASPASNR 738

Query: 528  GKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN-SLDPFPPRILKEEPKG-------K 579
               P  + +  R Q         Q +  P+ + EN   +   P   K E KG        
Sbjct: 739  AVTPSSEAKDSRLQ--------DQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEH 790

Query: 580  EKEVDGL------------LTSEPMGSPVSSKTE-------------------------- 601
             K++D L             TSE M   ++   E                          
Sbjct: 791  RKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSS 850

Query: 602  ---SVSDKEDKPPLAPSGGTEGPEQPPPPCPS---QTGSPPVGLIKGEDKDEGPVAEQVK 655
               S S K + P ++PS  +    +  P   S   QT SP     K + +++   AEQV+
Sbjct: 851  NCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVR 910

Query: 656  KSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSI-----PVLTAGQSGLYSPQY 710
            KSTLNPNAKEFNP     S  K ++TPTSP P+   +PS+     P     Q   ++P  
Sbjct: 911  KSTLNPNAKEFNPRS--FSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNM 968

Query: 711  ISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQA 770
            +  +P   + P VQ   +YP P++  +P  Q K   A  ++P QR DQH  ++   MM  
Sbjct: 969  MYPVP---VSPGVQ--PLYPIPMT-PMPVNQAKTYRAVPNMPQQRQDQHHQSA---MMHP 1019

Query: 771  AAAAGPPLVAATP-YSS-YIPYNPQQFPGQPAMMQPMAHYPSQ--PVFAPMLQSNPRMLT 826
            A+AAGPP+ A  P YS+ Y+ Y+PQQFP QP ++Q + HY SQ   V++P++Q N RM+ 
Sbjct: 1020 ASAAGPPIAATPPAYSTQYVAYSPQQFPNQP-LVQHVPHYQSQHPHVYSPVIQGNARMMA 1078

Query: 827  SGSHPQ-AIVSSSTPQYPSAEQPTPQALYA---------------------TVHQSYPHH 864
              +H Q  +VSSS  QY + EQ    A+YA                     ++ Q Y H 
Sbjct: 1079 PPTHAQPGLVSSSATQYGAHEQ--THAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHP 1136

Query: 865  ATQLHAH--QPQPATTPTGSQPQSQHA----APSPV---QHQAGQAPHLGSGQPQQNLYH 915
               LH H   PQP+ TPTG Q QSQH     APSPV   QHQA QA HL S Q Q  +YH
Sbjct: 1137 NATLHPHTPHPQPSATPTGQQ-QSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYH 1195

Query: 916  PGALTGTPPSLPPGPSAQSPQSSFP-QPAAVYAIHHQQLPHGFTN---MAHVTQAHVQTG 971
             G L  TPPS+ P  + QSPQ+SFP     V+ IH   +   +TN   MAHV QAHVQ+G
Sbjct: 1196 AG-LAPTPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSG 1254

Query: 972  ITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHP 1027
            +    P HP A  P  +M   PP    G PQ A+ QS +  +  ST + +PY+ HP
Sbjct: 1255 MV---PSHPTAHAPMMLMTTQPP----GGPQAALAQSALQPIPVSTTAHFPYMTHP 1303



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 37/134 (27%), Positives = 52/134 (38%), Gaps = 10/134 (7%)

Query: 362 GGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKT 421
           G    + +R    G  + PPR    L   +PG    A     GP  MS K Q+  +  + 
Sbjct: 115 GAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQ 174

Query: 422 LSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIP-- 479
                 +   +   PPP A     P  S   A+PA   +     P  S+V +SSA+ P  
Sbjct: 175 QQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPS-----PSSSSVSSSSATAPSS 229

Query: 480 ---VTSSVSDPGVG 490
               TS    PG+G
Sbjct: 230 VVAATSGGGRPGLG 243



 Score = 35.4 bits (80), Expect = 0.28
 Identities = 45/155 (29%), Positives = 57/155 (36%), Gaps = 14/155 (9%)

Query: 343 ASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPR-GPHHLDNSSPGPGSEARGI 401
           A+R   +  L +  R   RGG    ++ G  P  +  PP  GP     SSP   S+  G 
Sbjct: 22  AARWPGWRSLQRPARRSGRGGG--GAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGS 79

Query: 402 NGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVP--PPPAVGRMYPPRSPKSAAPAPIS 459
           NG          R L G   L  P  RP     +P   P A     PP +P  A+P    
Sbjct: 80  NGNGGGAFRPGSRRLLG---LGGPP-RPFVVLLLPLASPGA-----PPAAPTRASPLGAR 130

Query: 460 ASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISP 494
           AS P   +  A P      P    V  P   S+ P
Sbjct: 131 ASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKP 165



 Score = 33.9 bits (76), Expect = 0.82
 Identities = 34/110 (30%), Positives = 40/110 (36%), Gaps = 20/110 (18%)

Query: 21  QAVARRPPGGTSPPNGGLPGPLATSA-APPGP---------PAAASPCLGPVAAAGSGLR 70
           Q  ARR   G     G  PGP  ++A  PPGP         P +AS C G     G   R
Sbjct: 32  QRPARRSGRGGG---GAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFR 88

Query: 71  RGAEGILAPQPPPPQ-----QHQERPGAAAIGSARGQSTG--KGPPQSPV 113
            G+  +L    PP            PGA      R    G    PP+S V
Sbjct: 89  PGSRRLLGLGGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGV 138


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score =  106 bits (264), Expect = 1e-22
 Identities = 169/685 (24%), Positives = 227/685 (33%), Gaps = 128/685 (18%)

Query: 408  MSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSP--KSAAPAPISASCPEP 465
            +SP+ +RP    K  S+  + P G  S P  P      P  S   + +  +P +   P P
Sbjct: 801  VSPQTKRP--PTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTP 858

Query: 466  PIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELAR 525
            P     PT SA  P+    S  GV       PK +  P+ V     KE   T  P++   
Sbjct: 859  PSPKGAPTPSAVTPL----SPKGV----TLPPKETPTPSVVNLPFPKEGPATPAPKQ--- 907

Query: 526  IAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDG 585
                 P L         ++ R   A   +  S SP+ +  P PP      PKG      G
Sbjct: 908  ----APALSMTSS--SPKKARATPAPKGIPASPSPKGA--PTPPAATPPSPKG------G 953

Query: 586  LLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP------CPSQTGSPPVGL 639
              T  P  +P        S K      +P G    P   PP        PS  G+P    
Sbjct: 954  PATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPA 1013

Query: 640  IKGEDKDEGPVAEQVKKSTLNPNA------KEFNPTKPLLSVNKSTSTPTSPGPRTHSTP 693
            +        P A    K    P A      K      PL     +T   T P P+    P
Sbjct: 1014 VTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPK--GGP 1071

Query: 694  SIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPP 753
            + P L     G  +P   +  P    GPA  +P+  P P + + P  +G       + PP
Sbjct: 1072 ATPSL----KGAPTPPAATP-PSPKGGPATPSPKGAPMPPAATPPSPKGGL-----ATPP 1121

Query: 754  QRSDQHQPASAPPMMQAAAAAGPPLVAAT--------PYSSYIPYNPQQFPGQPAMMQPM 805
             +     PA+ PP  +   A  PP  A T        P        P+  P  PA   P 
Sbjct: 1122 HKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPS 1181

Query: 806  AHYPSQPVFAPMLQSNPRM--LTSGSHPQAIVSSS---TPQYPSAEQPTPQALYATVHQS 860
               P   +  P  +  P     T  S    + + S    P  P+A  P+P+   AT    
Sbjct: 1182 ---PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS-- 1236

Query: 861  YPHHATQLHAHQPQ-----PATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYH 915
             P  A    A  P      PAT P    P    A P  ++      PH G+         
Sbjct: 1237 -PKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGA--------- 1286

Query: 916  PGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAA 975
            P     TPPS   GP+   P+ +   PAA         P G                +  
Sbjct: 1287 PNPAVVTPPSPKGGPATSPPKGAPTPPAAT-----PPSPKG----------------SPG 1325

Query: 976  PPPHPGAPHPPQVMLLHP----------PQSHGGP----------PQGAVPQ-SGVPALS 1014
             PP  GAP PP V    P          P S GGP          P  A P   G PA++
Sbjct: 1326 TPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMT 1385

Query: 1015 ASTPSPYPYIGHPQAPLPPPGELKI 1039
              +P   P I  P+     P  + +
Sbjct: 1386 PPSPKRGPAIPSPKGDPTSPAVIPL 1410



 Score =  105 bits (261), Expect = 3e-22
 Identities = 177/741 (23%), Positives = 248/741 (33%), Gaps = 115/741 (15%)

Query: 345  REGKYIPLPQRVREGPRGGVRCSSSRGGR--PGLSSLPPRGPHHLDNSSPGPGSEARGIN 402
            +EG   P P   ++ P   +  SS +  R  P    +P   P      +P P +      
Sbjct: 897  KEGPATPAP---KQAPALSMTSSSPKKARATPAPKGIPA-SPSPKGAPTP-PAATPPSPK 951

Query: 403  GGPSRMSPK-------AQRPL-RGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAA 454
            GGP+  SPK       A  P  +G     SP   P+   + PP P  G   P  SPK  A
Sbjct: 952  GGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATP--SPK-GA 1008

Query: 455  PAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEP 514
            P P + + P P        S A+ P     S P   + +P SPK S A T + + +   P
Sbjct: 1009 PTPPAVTPPSP------KGSPAATPFPKGASTP--PAATPPSPKGSPAATPLPKGAPTTP 1060

Query: 515  GRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLD---PFPPRI 571
              TL   +       + G                 A     P   P        P PP  
Sbjct: 1061 AATLPSPKGGPATPSLKGAPTPP------------AATPPSPKGGPATPSPKGAPMPPAA 1108

Query: 572  LKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQ 631
                PKG      GL T    G+P +      S K       P G    P   PP     
Sbjct: 1109 TPPSPKG------GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1162

Query: 632  TGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHS 691
              +PP    KG            K     P+ K   PT P  +         +P P+   
Sbjct: 1163 LATPPP---KGAPTTPAATPPSPKGGLATPSPKG-APTTPAATPPSPKGGLATPSPKGAP 1218

Query: 692  TPSIPVLTAGQSGLYSPQ-------YISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKY 744
            T       + + GL +P          +  P    GPA   P+  P P + + P  +G  
Sbjct: 1219 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGL 1278

Query: 745  RGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQP 804
                 + PP +   +     PP  +   A  PP  A TP ++  P +P+  PG P    P
Sbjct: 1279 -----ATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAA-TPPSPKGSPGTP----P 1328

Query: 805  MAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHH 864
                P+ P   P        L + + P +    +TP   S E PTP A       + P H
Sbjct: 1329 PKGAPTPPAVTPPSPKGTPTLPA-TTPSSKGGPTTPS--SKEGPTPPA-------ATPSH 1378

Query: 865  ATQLHAHQPQPATTPTGSQPQSQHAAP-----SPVQHQAGQAPHLGSGQPQQNLYHPGAL 919
                    P P   P    P+    +P     SP +  A      G+  P +    P A+
Sbjct: 1379 KGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAV 1438

Query: 920  TGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPH 979
              TP SL   P+  +P+     PA   +     LP           A  Q   +++P   
Sbjct: 1439 --TPVSLKKAPATSAPKGG---PATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKA 1493

Query: 980  P------GAPHPPQVMLLHP------PQSHGGP------------PQGAVPQSGV--PAL 1013
            P      GAP  P V+   P      P S   P            P    P+  +  PA+
Sbjct: 1494 PATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAM 1553

Query: 1014 SASTPSPYPYIGHP-QAPLPP 1033
            +  +P   P I  P +AP  P
Sbjct: 1554 TVPSPKKTPAIPTPKEAPATP 1574



 Score = 95.9 bits (237), Expect = 2e-19
 Identities = 187/770 (24%), Positives = 257/770 (33%), Gaps = 119/770 (15%)

Query: 335  SGRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGR--PGLSSLPPRG-----PHHL 387
            S +  P+  S +G   P P      P+GG    S +G    P ++   P+G     P   
Sbjct: 972  SPKGGPATPSPKGAPTP-PAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPK 1030

Query: 388  DNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGET--SVPPPPAVGRMY 445
              S+P P +      G P+        P   A TL SP   P+  +    P PPA     
Sbjct: 1031 GASTP-PAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAA---- 1085

Query: 446  PPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTD 505
             P SPK     P     P PP  +  P+    +        P   + +P SPK  LA   
Sbjct: 1086 TPPSPKGGPATPSPKGAPMPPAATP-PSPKGGLATPPHKGAPTTPAATPPSPKGGLATPP 1144

Query: 506  VKELSTKEPGRTLEPQE-LA----RIAGKVPGLQNEQKRFQLEELRKFGAQFK---LQPS 557
             K   T        P+  LA    + A   P       +  L      GA        PS
Sbjct: 1145 PKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1204

Query: 558  -----SSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPL 612
                 ++P     P  P      PKG      GL T  P G+P +      S K      
Sbjct: 1205 PKGGLATPSPKGAPTTPAATPPSPKG------GLATPSPKGAPTTPAATPPSPKGGPATP 1258

Query: 613  APSGGTEGPEQPPPPC------PSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEF 666
             P G    P   PP        P   G+P   ++       GP     K +   P A   
Sbjct: 1259 PPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPP 1318

Query: 667  NP-------------TKPLLSVNKSTSTPTSP--------GPRTHST---PSIPVLTAGQ 702
            +P             T P ++      TPT P        GP T S+   P+ P  T   
Sbjct: 1319 SPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSH 1378

Query: 703  SGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGA-----KGSLPPQRSD 757
             G   P      P+   GPA+ +P+    P S +V     K   A     +G+  P + D
Sbjct: 1379 KG--GPAMTPPSPK--RGPAIPSPK--GDPTSPAVIPLSPKKAPATPVTREGAATPSKGD 1432

Query: 758  QHQPASAPPMMQAAAAAGPPLVA-ATPYSSYIPYNPQQFPGQPAMMQPMAHYP----SQP 812
               PA  P  ++ A A   P    ATP S   P  P   P  P+  +P A       S P
Sbjct: 1433 LTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTP--PSPKEPPAPKQVATSSSP 1490

Query: 813  VFAPMLQSNPRMLTSGSHPQAIVSS--STPQYPSAEQPTPQALYATVHQSYPHHATQLHA 870
              AP   + P  + + + P  I SS    P  PS+ +         + +  P       A
Sbjct: 1491 KKAP---ATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEA 1547

Query: 871  HQPQPATTP----TGSQPQSQHAAPSPVQHQAGQAP------HLGSGQPQQNLYHPGALT 920
              P   T P    T + P  + A  +P   +A   P      + G+  P++ L  P A+T
Sbjct: 1548 LIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPP-AVT 1606

Query: 921  GTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHP 980
               P   P P A +P S    PA          P G      VT + ++   T+      
Sbjct: 1607 SPSPKEAPTPPAVTPPSPEKGPAT-------PAPKGTPTSPPVTPSSLKDSPTS------ 1653

Query: 981  GAPHPPQV---MLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHP 1027
                P  V   M    PQ+  G P    P +    L A  P   P I  P
Sbjct: 1654 ----PASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAP 1699



 Score = 94.7 bits (234), Expect = 4e-19
 Identities = 160/674 (23%), Positives = 219/674 (32%), Gaps = 150/674 (22%)

Query: 375  GLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMS----PKAQRPLRGAK----TLSSPS 426
            G+S  P          S GP +    ++   S +     P+     +G+K    T  SP+
Sbjct: 798  GVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPT 857

Query: 427  NRPSGETSVPPPPAVGRMYPP--RSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSV 484
              P      P P AV  + P     P    P P   + P P  G A P    +  ++ + 
Sbjct: 858  --PPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTS 915

Query: 485  SDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEE 544
            S P     +PA   I  +P+  K   T        P+                       
Sbjct: 916  SSPKKARATPAPKGIPASPSP-KGAPTPPAATPPSPK----------------------- 951

Query: 545  LRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVS 604
                         ++P     P PP      PKG      G  T  P G+P        S
Sbjct: 952  ----------GGPATPSPKWAPTPPAATPPSPKG------GPATPSPKGAPTPPAATPPS 995

Query: 605  DKEDKPPLAPSGGTEGPEQPPPPCPSQTGSP-PVGLIKGEDKDEGPVAEQVKKSTLNPNA 663
             K      +P G    P   P   PS  GSP      KG            K S      
Sbjct: 996  PKGGPATPSPKGAPTPPAVTP---PSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPL 1052

Query: 664  KEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAV 723
             +  PT P  ++      P +P  +   TP  P  T               P    GPA 
Sbjct: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAPTP--PAATP--------------PSPKGGPAT 1096

Query: 724  QAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATP 783
             +P+  P P + + P  +G       + PP +     PA+ PP  +   A  PP  A T 
Sbjct: 1097 PSPKGAPMPPAATPPSPKGGL-----ATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTT 1151

Query: 784  YSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYP 843
             ++  P +P+     P    P    P+ P   P    +P+   +   P+       P  P
Sbjct: 1152 PAA-TPPSPKGGLATP----PPKGAPTTPAATP---PSPKGGLATPSPK-----GAPTTP 1198

Query: 844  SAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPH 903
            +A  P+P+   AT                P P   PT         A +P   + G A  
Sbjct: 1199 AATPPSPKGGLAT----------------PSPKGAPT-------TPAATPPSPKGGLATP 1235

Query: 904  LGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHV 963
               G P      P A   TPPS   GP+   P+ +   PAA                   
Sbjct: 1236 SPKGAPTT----PAA---TPPSPKGGPATPPPKGAPTPPAA------------------- 1269

Query: 964  TQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSAST-PSPYP 1022
            T   ++ G+  A PPH GAP+P  V    PP   GGP     P  G P   A+T PSP  
Sbjct: 1270 TPPSLKGGL--ATPPHKGAPNPAVVT---PPSPKGGP--ATSPPKGAPTPPAATPPSPKG 1322

Query: 1023 YIGHPQ---APLPP 1033
              G P    AP PP
Sbjct: 1323 SPGTPPPKGAPTPP 1336



 Score = 83.2 bits (204), Expect = 1e-15
 Identities = 169/680 (24%), Positives = 236/680 (34%), Gaps = 95/680 (13%)

Query: 415  PLRGAKTLSSPS-NRPSGETSVPPPP-------AVGRMYPPRSPKSAAPAPISASCPEPP 466
            PL  A   +SPS    S    +P  P       ++G   P   P S+  +P+  +     
Sbjct: 561  PLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASV 620

Query: 467  I--GSAVPTSSASIPVTSSVSDPGVGS--ISPASPKISLAPTDVKELSTKEPGRTLEPQE 522
            I   S     SA   + SS+  P V +  +  A P   +APT  K  ST     +   + 
Sbjct: 621  IKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPA-GVAPTTAKGTSTYTTTASPFLEG 679

Query: 523  LARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQP-SSSPENSLDPFPPRILKEE------ 575
               +A K     +  K   L  L       +  P + SP+N+  P    +L  E      
Sbjct: 680  TVSLAPK----NHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVP 735

Query: 576  -----PKGKE---KEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGT-----EGPE 622
                 P G     K+VDG+  +  +    SS  E  ++       A S GT     + P 
Sbjct: 736  SPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPS 795

Query: 623  QPPPPCPSQTGSPPVGLIKGEDKDEGPVAE------QVKKSTLNPNAKEFNPTKPLLSVN 676
                    QT  PP    KG    + P+         V+ S L  N+  F  +K   +  
Sbjct: 796  PLGVSVSPQTKRPPTK--KGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPA-- 851

Query: 677  KSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQI------HMGPAVQAPQMYP 730
             +T +PT P P+   TPS  V      G+  P   +  P +        GPA  AP+  P
Sbjct: 852  -TTHSPTPPSPKGAPTPSA-VTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAP 909

Query: 731  -YPVSNSVPGQQGKYRGAKG--SLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSY 787
               +++S P +       KG  + P  +     PA+ PP  +   A   P  A TP ++ 
Sbjct: 910  ALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAA- 968

Query: 788  IPYNPQQFPGQPAMM---QPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPS 844
             P +P+  P  P+      P A  P  P   P   S       G+     V+  +P+   
Sbjct: 969  TPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPS-----PKGAPTPPAVTPPSPKGSP 1023

Query: 845  AEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHL 904
            A  P P+        S P  AT   + +  PA TP      +  AA  P        P L
Sbjct: 1024 AATPFPKGA------STPPAATP-PSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSL 1076

Query: 905  GSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQL---PHGFTNMA 961
                       P     TPPS   GP+  SP+ +   PAA        L   PH      
Sbjct: 1077 KGA--------PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTT 1128

Query: 962  HVTQAHVQTGITAAPPPHPGAPHPPQVM-------LLHPPQSHGGPPQGAVPQSGVPALS 1014
                     G  A PPP  GAP  P          L  PP         A P S  P   
Sbjct: 1129 PAATPPSPKGGLATPPPK-GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPS--PKGG 1185

Query: 1015 ASTPSPYPYIGHPQAPLPPP 1034
             +TPSP      P A  P P
Sbjct: 1186 LATPSPKGAPTTPAATPPSP 1205



 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 163/701 (23%), Positives = 231/701 (32%), Gaps = 115/701 (16%)

Query: 417  RGAKTLSSPSNRPSGETSVPPPPAVG---RMYPPRSPKSAAPAPISASCPEPPIGS---- 469
            +G  T+SS +  PSG  +V    ++     +    SP +    P+ A  P   +G+    
Sbjct: 383  KGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLV 442

Query: 470  --------AVPTSSASIP--VTSSVSDPGVGSISPASPK-ISLAPTDVKELSTKEPGRTL 518
                    A PT++  +   V+  +S   + +I P SP  + +AP   KE ST +   TL
Sbjct: 443  VTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPST-QVATTL 501

Query: 519  ---------EPQELARIAGKVPGLQNEQKRFQLEELRKFGAQF---------KLQPS--- 557
                     +P++L  +   V      QK  Q       GA F         K  P+   
Sbjct: 502  RIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLP 561

Query: 558  ---SSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPM--GSPVSSKTESVSDKEDKPPL 612
               ++P+NS          E P   E  +      EP+  G P SS T  +        +
Sbjct: 562  LVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLG-VNSSASV 620

Query: 613  APSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTL------------- 659
              +    GP+   P   S   +P V     E  D   VA    K T              
Sbjct: 621  IKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGT 680

Query: 660  ------NPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISY 713
                  N   KE   T   L    S + P +P P+    P   ++ A       P+    
Sbjct: 681  VSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLA-------PEIPKS 733

Query: 714  IPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAA 773
            +P   + PA   P         S          +    P + S     AS+   +   A 
Sbjct: 734  VPSPSLPPAGTPPGTKKVD-GISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLAD 792

Query: 774  AGPPL-VAATPYSSYIPYNPQQFPGQPAMMQPMAHY--PSQPVFAPMLQSNPRMLTSGSH 830
            +  PL V+ +P +      P    G      P+ +   P  PV A  L  N         
Sbjct: 793  SPSPLGVSVSPQTK----RPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKD 848

Query: 831  PQAIVSSSTPQYPSAEQPTPQALY-----------------ATVHQSYPHHATQLHAHQP 873
              A   S TP  P    PTP A+                  + V+  +P       A + 
Sbjct: 849  SPATTHSPTPPSPKGA-PTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQ 907

Query: 874  QPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTP-PSLPPGPSA 932
             PA + T S P+   A P+P    A  +P      P      P     TP P   P P A
Sbjct: 908  APALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPA 967

Query: 933  QSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLH 992
             +P S    PA          P G       T    + G   A P   GAP PP V    
Sbjct: 968  ATPPSPKGGPAT-------PSPKGAPTPPAATPPSPKGG--PATPSPKGAPTPPAVT--- 1015

Query: 993  PPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQA-PLP 1032
            PP   G P     P+      +A+ PSP    G P A PLP
Sbjct: 1016 PPSPKGSPAATPFPKGASTPPAATPPSPK---GSPAATPLP 1053



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 78/327 (23%), Positives = 115/327 (35%), Gaps = 63/327 (19%)

Query: 381  PRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA 440
            P  P   + SSP P        G PS   PK +  +  A T  SP   P+     PP P 
Sbjct: 1571 PATPSSKEASSP-PAVTPSTYKGAPS---PK-ELLIPPAVTSPSPKEAPTPPAVTPPSPE 1625

Query: 441  VGRMYP---------PRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGS 491
             G   P         P +P S   +P S +     +G+ VP +S  +P     +      
Sbjct: 1626 KGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVL 1685

Query: 492  ISPA--SPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFG 549
            ++PA  S  I  APT  K   TK+   T  P          P  +N  K           
Sbjct: 1686 VAPAPESTPIITAPTR-KGPQTKKSSATSPP------ICPDPSAKNGSK----------- 1727

Query: 550  AQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDK 609
                      P +++ P P   ++++     K  D   + +   +P  SK  +       
Sbjct: 1728 ---------GPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKAST------- 1771

Query: 610  PPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPT 669
             PL  +   +   +P     S   SPPV L         P+A     +   P  ++F P+
Sbjct: 1772 -PLTAAAFEKVLPKPESASVSAAPSPPVSL---------PLAPSPVPTL--PPKQQFLPS 1819

Query: 670  KPLLSVNKSTSTPTSPGPRTHSTPSIP 696
             P L V +S S P +P       P IP
Sbjct: 1820 SPGL-VLESPSKPLAPADEDELLPLIP 1845



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 136/646 (21%), Positives = 210/646 (32%), Gaps = 101/646 (15%)

Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPP----------PAVGRMYPPRSPKSAA 454
           P   +  A  P+  A ++++   +P    ++PPP           A  +  P  SP + A
Sbjct: 17  PQPQAETAVLPMSSALSVTAALGQPG--PTLPPPCSPAPQQCPLSAANQASPFPSPSTIA 74

Query: 455 PAPISASCPEPPIGSAVPTSSAS--------------IPVTSSVSDP-------GVGSIS 493
             P+    P+   G+A+P  +A                P   +++ P       G  S S
Sbjct: 75  STPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSS 134

Query: 494 PASPKISLAPTDVKELSTKEPGRTLEPQELA------RIAGKVPGLQNEQKRFQLEELRK 547
                ++LAP  V++ S   P     P  +A       I    P   +E K      L K
Sbjct: 135 APLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPK----TNLNK 190

Query: 548 FGAQFKLQPSSSPENSLDPFPPRILKEEP---KGKEKEVDGLLTSEPMGSPVSS------ 598
             ++    P  +P       PP I+   P         +   + S P  +P ++      
Sbjct: 191 VPSEVVPNPKGTPS------PPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASP 244

Query: 599 --KTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKK 656
             K  ++S     P    S   +GP  PP      T S PV  +    K  GP       
Sbjct: 245 QVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPV--VTSSQKTAGPNTPPDFP 302

Query: 657 STLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQS--GLYSPQYISYI 714
            +L  +    +      S   S       GP   S P++  ++   S  G   P   S I
Sbjct: 303 ISLGSHLAPLHQ-----SSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVI 357

Query: 715 PQI----HMGPAVQAPQMYPYPVSNSVPGQQGKYR-GAKGSLPPQRSDQHQPASAPPMMQ 769
           P +     + PA  A      P  +  P           GSL    S    P ++  +  
Sbjct: 358 PPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKS 417

Query: 770 AA-AAAGPPLVAATPYSS-----YIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPR 823
           +  A    PLVA  P SS      +  NP      P     +A   S P     + S P 
Sbjct: 418 SPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPP-----MSSGPI 472

Query: 824 MLTSGSHPQAIVSSS-TPQYPSAEQPTPQALYATVHQSYPHHATQLHAH--QPQPATTPT 880
                + P A+V +   P+ PS +  T   +  +     P     L +      P     
Sbjct: 473 SNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDL 532

Query: 881 GSQPQSQHAAP-SPVQHQAGQAPH-------LGSGQPQQNLYHPGALTGTPPSLPPGPSA 932
            + P S   AP SP   QAG           L    P+ +       T + P +P  P A
Sbjct: 533 QTVPASLEGAPFSPA--QAGLTTKKDPTVLPLVQAAPKNSPSFQS--TSSSPEIPLSPEA 588

Query: 933 QSPQSSFPQPAAV-YAIHHQQLPHGFTNMAHVTQAHVQTGITAAPP 977
              + S  +P  +         P G  + A V +     G  +A P
Sbjct: 589 TLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGP 634



 Score = 39.7 bits (91), Expect = 0.015
 Identities = 35/122 (28%), Positives = 48/122 (39%), Gaps = 9/122 (7%)

Query: 4    PQPLQQPSQPQQPPPTQQA--VARRPPGGTSPPNGGLPGPLATSAAPPGP-----PAAAS 56
            P P   P+ P   PP+ +       P G  +PP    P P  + AA P P     P AA+
Sbjct: 980  PSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAAT 1039

Query: 57   PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPG--AAAIGSARGQSTGKGPPQSPVF 114
            P     + A + L +GA    A   P P+     P    A    A    + KG P +P  
Sbjct: 1040 PPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP 1099

Query: 115  EG 116
            +G
Sbjct: 1100 KG 1101



 Score = 39.7 bits (91), Expect = 0.015
 Identities = 39/124 (31%), Positives = 46/124 (37%), Gaps = 22/124 (17%)

Query: 4    PQPLQQPSQPQQPPPTQQAVARRPPGG--TSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
            P P   P+ P   PP+       P GG  T PP G    P AT  +P G  A  SP   P
Sbjct: 1143 PPPKGAPTTPAATPPS-------PKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAP 1195

Query: 62   VAAAGS------GLR----RGAEGILAPQPPPPQQHQERP---GAAAIGSARGQSTGKGP 108
               A +      GL     +GA    A  PP P+     P   GA    +A   S   GP
Sbjct: 1196 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGP 1255

Query: 109  PQSP 112
               P
Sbjct: 1256 ATPP 1259



 Score = 39.7 bits (91), Expect = 0.015
 Identities = 31/112 (27%), Positives = 39/112 (34%), Gaps = 6/112 (5%)

Query: 3    KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPV 62
            K  P   P +    PP     + +   GT PP G    P  T  +P G P    P   P 
Sbjct: 1298 KGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTL--PATTPS 1355

Query: 63   AAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQS--TGKGPPQSP 112
            +  G       EG   P   P   H+  P        RG +  + KG P SP
Sbjct: 1356 SKGGPTTPSSKEGPTPPAATP--SHKGGPAMTPPSPKRGPAIPSPKGDPTSP 1405



 Score = 38.5 bits (88), Expect = 0.033
 Identities = 35/116 (30%), Positives = 44/116 (37%), Gaps = 14/116 (12%)

Query: 4    PQPLQQPSQPQQPPPTQQAVARRPP--GGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
            P P   P  P   PP+ +     PP  G  + P    P P    A PP   A  +P   P
Sbjct: 1097 PSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1156

Query: 62   VAAAGSGLR----RGAEGILAPQPPPPQQHQERPGAAAIGSARG-QSTGKGPPQSP 112
             +  G GL     +GA    A  PP P+      G  A  S +G  +T    P SP
Sbjct: 1157 PSPKG-GLATPPPKGAPTTPAATPPSPK------GGLATPSPKGAPTTPAATPPSP 1205



 Score = 38.5 bits (88), Expect = 0.033
 Identities = 34/113 (30%), Positives = 47/113 (41%), Gaps = 11/113 (9%)

Query: 4    PQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGP-LATSAAPPGPPAAASPCLGPV 62
            P P   P+ P   PP+ +       G  +PP+ G P P + T  +P G PA + P   P 
Sbjct: 1258 PPPKGAPTPPAATPPSLKG------GLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPT 1311

Query: 63   -AAAGSGLRRGAEGILAPQ--PPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
              AA     +G+ G   P+  P PP      P       A   S+ KG P +P
Sbjct: 1312 PPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSS-KGGPTTP 1363



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 35/119 (29%), Positives = 42/119 (35%), Gaps = 19/119 (15%)

Query: 4    PQPLQQPSQPQQPPPTQQA--VARRPPGGTSPPNGGLPGPLATSAAP-----PGPPAAA- 55
            P P   P+ P   PP+ +       P    +PP    P P    A P     P PPAA  
Sbjct: 934  PSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATP 993

Query: 56   -SPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQST-GKGPPQSP 112
             SP  GP   +  G         AP PP       +   AA    +G ST     P SP
Sbjct: 994  PSPKGGPATPSPKG---------APTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSP 1043



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 34/119 (28%), Positives = 41/119 (34%), Gaps = 19/119 (15%)

Query: 4    PQPLQQPSQPQQPPPTQQ---AVARRPPGGTSPPNGGLPGPLATSAAP-----PGPPAAA 55
            P P    + P   PP+ +   A    P G  + P   LP P    A P     P PPAA 
Sbjct: 1027 PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAAT 1086

Query: 56   --SPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
              SP  GP   +  G         AP PP       + G A        +T    P SP
Sbjct: 1087 PPSPKGGPATPSPKG---------APMPPAATPPSPKGGLATPPHKGAPTTPAATPPSP 1136



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 33/121 (27%), Positives = 43/121 (35%), Gaps = 9/121 (7%)

Query: 4    PQPLQQPSQPQQPPPTQQA--VARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
            P P   P+ P   PP+ +       P G  + P    P P    A PP   A   P   P
Sbjct: 1212 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP 1271

Query: 62   VAAAGSGL----RRGAEGILAPQPPPPQ--QHQERPGAAAIGSARGQSTGKGPPQSPVFE 115
             +  G GL     +GA       PP P+       P  A    A    + KG P +P  +
Sbjct: 1272 PSLKG-GLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPK 1330

Query: 116  G 116
            G
Sbjct: 1331 G 1331



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 27/105 (25%), Positives = 36/105 (34%), Gaps = 9/105 (8%)

Query: 6    PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAA 65
            P      P  PPP     A  PP  T P   G P   AT+ +  G P   S   GP   A
Sbjct: 1317 PPSPKGSPGTPPPKG---APTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPA 1373

Query: 66   GSGLRRGAEGILAPQP------PPPQQHQERPGAAAIGSARGQST 104
             +   +G   +  P P      P P+     P    +   +  +T
Sbjct: 1374 ATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPAT 1418



 Score = 35.0 bits (79), Expect = 0.37
 Identities = 37/125 (29%), Positives = 45/125 (36%), Gaps = 24/125 (19%)

Query: 4    PQPLQQP------SQPQQ----PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAP----- 48
            P P Q P      S P++    P P     +  P G  +PP    P P    A P     
Sbjct: 903  PAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWA 962

Query: 49   PGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKG- 107
            P PPAA  P   P     +   +GA    A  PP P+      G  A  S +G  T    
Sbjct: 963  PTPPAATPP--SPKGGPATPSPKGAPTPPAATPPSPK------GGPATPSPKGAPTPPAV 1014

Query: 108  PPQSP 112
             P SP
Sbjct: 1015 TPPSP 1019



 Score = 35.0 bits (79), Expect = 0.37
 Identities = 34/120 (28%), Positives = 43/120 (35%), Gaps = 18/120 (15%)

Query: 10   PSQPQQPPPTQQA--VARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGS 67
            P+ P   PP+ +       P G   PP    P P    A PP   A  +P   P +  G 
Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG- 1138

Query: 68   GLR----RGAEGILAPQP---------PPPQQHQERPGAAAIGSARGQST--GKGPPQSP 112
            GL     +GA    A  P         PPP+     P A       G +T   KG P +P
Sbjct: 1139 GLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1198



 Score = 35.0 bits (79), Expect = 0.37
 Identities = 28/121 (23%), Positives = 43/121 (35%), Gaps = 7/121 (5%)

Query: 4    PQPLQQPSQPQQPPPTQQAVARRP---PGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
            P P   P+ P   P + +     P    G  +P  G L  P  T  +    PA ++P  G
Sbjct: 1396 PSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGG 1455

Query: 61   PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
            P   +     +G   + A  PP P++       A   S +       P  +P    V  +
Sbjct: 1456 PATPSS----KGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPS 1511

Query: 121  S 121
            S
Sbjct: 1512 S 1512



 Score = 34.7 bits (78), Expect = 0.48
 Identities = 32/127 (25%), Positives = 41/127 (32%), Gaps = 20/127 (15%)

Query: 4    PQPLQQPSQPQQPPPTQQA--VARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
            P P   P+ P   PP+ +       P G  + P    P P    A P    A  +P   P
Sbjct: 1189 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1248

Query: 62   VAAAGSGLRRGAEGILAPQPP-------------PPQQHQERPGAAAIGSARG---QSTG 105
             +  G       +G  AP PP             PP +    P      S +G    S  
Sbjct: 1249 PSPKGGPATPPPKG--APTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPP 1306

Query: 106  KGPPQSP 112
            KG P  P
Sbjct: 1307 KGAPTPP 1313



 Score = 33.9 bits (76), Expect = 0.82
 Identities = 61/258 (23%), Positives = 96/258 (37%), Gaps = 39/258 (15%)

Query: 796  PGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQAL-Y 854
            PG+     P      Q +  P  ++    ++S     A +    P  P    P PQ    
Sbjct: 2    PGEATETVPATE---QELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPL 58

Query: 855  ATVHQSYPHHA------TQLHAHQPQPAT---TPTGSQPQSQHAAPSPVQHQAGQAPHLG 905
            +  +Q+ P  +      T L    PQ ++    P G+ P++    P+ +      A  L 
Sbjct: 59   SAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAA-LA 117

Query: 906  SGQPQQNLYHPGALTGTPPSLPP------GPSAQSPQSSFP-----QPAAVYAIHHQQLP 954
               P   +  P  L GTP S  P       P +    S+FP      P +V       + 
Sbjct: 118  LASP---MIAP-TLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSV- 172

Query: 955  HGFTNMAHVTQAHVQTGITAAPP---PHP-GAPHPPQVMLLHPPQSHGGPPQGAVPQSGV 1010
               T  A +  +  +T +   P    P+P G P PP ++   P   H   P  ++ QSGV
Sbjct: 173  --ITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVP--YHCVTPMASI-QSGV 227

Query: 1011 PALSASTPSPYPYIGHPQ 1028
             +L  +TP+    I  PQ
Sbjct: 228  ASLPQTTPTTTLAIASPQ 245



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 25/98 (25%), Positives = 34/98 (34%), Gaps = 6/98 (6%)

Query: 16   PPPTQQAVARRPP-GGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAE 74
            PP  +   A  PP G  +PP    P P  +   PP   A   P + P +  G+       
Sbjct: 1294 PPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATT 1353

Query: 75   GILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
                  P  P   +     AA  S +G     GP  +P
Sbjct: 1354 PSSKGGPTTPSSKEGPTPPAATPSHKG-----GPAMTP 1386


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 99.8 bits (247), Expect = 1e-20
 Identities = 188/756 (24%), Positives = 257/756 (33%), Gaps = 123/756 (16%)

Query: 357  REGP-RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRP 415
            R GP R     S +   RP  S    R P    N+SPGP S   G   G +R  P  Q+ 
Sbjct: 76   RAGPTRSAGTSSRNPASRPPASGRGERAPP-AKNTSPGPVSSP-GRASGTTRPGPLGQKG 133

Query: 416  LR---------GAKT-------LSSPSNRP-SGETSVPPPPAVGRMYPPRSPKSAAPAPI 458
            LR         G  T       LS+ + R  SG T   P PA+ R       +   P P 
Sbjct: 134  LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 193

Query: 459  SASCPEPPI-GSAVPTSSASIPVTSSVS-------DPGVGSISPASPKISLAPTDVKELS 510
             ++ P PP  G     SSAS   T+  S         G G   PAS  +S + T +   +
Sbjct: 194  PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253

Query: 511  TKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQ-----------------FK 553
               P     P+  A  +   P      +  Q+   RK  A                   K
Sbjct: 254  RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTK 313

Query: 554  LQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLA 613
             +P   P+N+  P P  +    P         L T  P+  P  S   S+      P   
Sbjct: 314  ARPVPPPDNAATPLPATLPPSPP---------LATPLPLAPPSPSAPPSLQTLPSPPATP 364

Query: 614  PSGGTEGPEQPPPPC-PSQTGSPPVGL-----IKGEDKDEGPVAEQVKKSTLNPNAKEFN 667
            PS        PP    PS    PP+ +              P+A    ++T +  +    
Sbjct: 365  PSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQ 424

Query: 668  PTKPLLSVN--KSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAV-- 723
             T   L+++  ++ ++ TSP     + P  P L A  S   SP       Q  + PAV  
Sbjct: 425  ATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPL-----QTSLSPAVSP 479

Query: 724  -QAP-QMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAA 781
              +P  ++P    +S+     +   +   +PP  +   Q + APP +Q      PP    
Sbjct: 480  LSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLET---QSSLAPPSLQT-----PPASLT 531

Query: 782  TPYSSYIPY---NPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSS 838
            TP    +P     P Q    P +  P    P  P   P+      + T      + +++ 
Sbjct: 532  TPPLENLPSLAPPPLQTASAP-LTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATP 590

Query: 839  TPQYPSA-----EQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSP 893
             PQ P A      Q  P    + +    P     L     Q   +P  S P S  A PSP
Sbjct: 591  PPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSP 650

Query: 894  VQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPP-GPSAQSPQSSFPQPAAVYAIHHQQ 952
             Q     A HL           P     +PP+ PP  PSA  P  + P  AA        
Sbjct: 651  -QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA-------- 701

Query: 953  LPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQV-------MLLHPPQSHGGPPQ--G 1003
                           V     A+PP  P A  PPQ         L  PP     PP    
Sbjct: 702  -----------PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPS 750

Query: 1004 AVPQSGVPALSASTP---SPYPYIGHPQAPL--PPP 1034
            A P   VP L A+ P    P P    P +PL  PPP
Sbjct: 751  ATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPP 786



 Score = 90.5 bits (223), Expect = 7e-18
 Identities = 165/720 (22%), Positives = 228/720 (31%), Gaps = 85/720 (11%)

Query: 334  GSGRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPG 393
            G G + P+  S      PL    R GP       S+RG         PR P H     P 
Sbjct: 231  GGGLQRPASRSLSSSATPLSSPARSGP-------SARG--------TPRAPAHPSQPKPK 275

Query: 394  PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYP---PRSP 450
                 R     P R           +  L++PS   +    VPPP       P   P SP
Sbjct: 276  GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSP 335

Query: 451  KSAAPAPISASCPE-PPIGSAVPTSSASIPVTS--SVSDPGVGSISPASPKISLAPTDVK 507
              A P P++   P  PP    +P+  A+ P  +  S++ P +     A P +   P    
Sbjct: 336  PLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPM----QAPPSLQTIPPIQV 391

Query: 508  ELSTKEPGRTLEPQELARIAGKVP---GLQNEQKRFQLEELRKFGAQFKLQPSSSPENSL 564
              S   P     P  LA  + +     G    Q       +     Q  L   S P ++ 
Sbjct: 392  PHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTP 451

Query: 565  DPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT-----ESVSDKEDKPPLAPSGGTE 619
               PP    + P           +  P  SP+SS       +++S      P AP     
Sbjct: 452  PDSPPL---QAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLI 508

Query: 620  GP--EQPPPPCPSQTGSPPVGLIKGEDKDEGPVAE---QVKKSTLNPNAKEFNPTKPLLS 674
             P  E      P    +PP  L     ++   +A    Q   + L     E  P      
Sbjct: 509  MPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP 568

Query: 675  VNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVS 734
            +    S  T+P P T S+ + P   A  + L SP  +  +P   + P    P   P  ++
Sbjct: 569  LQAPPSPLTTPPPETPSSIATPPPQAPPA-LASPP-LQGLPSPPLSPLATPPPQAPPXLA 626

Query: 735  NSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQ 794
                            LPP ++    PAS PP+   A  +     A   +    P++P  
Sbjct: 627  ----------------LPPLQAPPSPPAS-PPLSPLATPSPQAPNALAVHLLQAPFSPPP 669

Query: 795  FPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALY 854
             P   A   P A  P  P   P  Q+ P +            +S P  PSA  P      
Sbjct: 670  SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP------ 723

Query: 855  ATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLY 914
                   P     L A   Q   +P  S P S  A P P      + P L +  P Q   
Sbjct: 724  -------PQAPPPLAAPPLQVPPSPPASPPMSPSATPPP------RVPPLLAAPPLQVPP 770

Query: 915  HPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITA 974
             P      P SLP  P A+ P  + P  A          P  F   A  + +        
Sbjct: 771  SP------PASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 824

Query: 975  APPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQAPLPPP 1034
            A PP    P     +L  PP     P   A  +   P    S   P   +     P PPP
Sbjct: 825  ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 884



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 169/713 (23%), Positives = 247/713 (34%), Gaps = 95/713 (13%)

Query: 357  REGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPL 416
            R+  + G    +     PGL  L PR P      SP P          P  ++P A R L
Sbjct: 5    RDKAKAGAAARTPAARAPGL--LTPRPP-----GSPRP----------PPPVTPAALRVL 47

Query: 417  RGAKTLSSP--SNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTS 474
              A  +     + R  G      P +  R  P RS  +++  P S   P    G   P +
Sbjct: 48   GAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRP-PASGRGERAPPA 106

Query: 475  SASIPVTSSVSDPG-------VGSISPASPKISLAPTDVKELSTKEPGRTLEPQELAR-I 526
              + P    VS PG        G +     +IS   T  +  +T+ P R+       R  
Sbjct: 107  KNTSP--GPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDT 164

Query: 527  AGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGL 586
            +G  PG  +          R  G +  L     P  S  P PP    E P+         
Sbjct: 165  SGPTPGTPSPA---MARRSRAAGTEVGLP---RPAPSARPRPPT---EGPRKSVSSASEH 215

Query: 587  LTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGP-EQPPPPCPSQTGSPPVGLIKGEDK 645
             T+EP  SP + +  S      +P       +  P   P    PS  G+P       + K
Sbjct: 216  STTEP--SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK 273

Query: 646  DEGPVAEQVKKSTLNPNAKEFNPTK-PLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSG 704
             +G   + ++   + P  K+  P   PL S   +T +P+    R    P         + 
Sbjct: 274  PKG--LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATL 331

Query: 705  LYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASA 764
              SP   + +P     P+   P +   P   + P  Q          PP  +    P  A
Sbjct: 332  PPSPPLATPLPLAPPSPSAP-PSLQTLPSPPATPPSQA---------PPSMTTP--PMQA 379

Query: 765  PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRM 824
            PP +Q      PP+    P+S   P    Q P  P  +  +    S  + +P LQ+    
Sbjct: 380  PPSLQTI----PPI--QVPHSLTSP--SLQAPPSPLALSSLQATTS--LGSPTLQATHSF 429

Query: 825  LTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQP 884
            LT  S  Q   S ++P  P++  P    L A +          L A  P   +      P
Sbjct: 430  LTM-SPRQTQASLTSPSRPASTPPDSPPLQAPL---------SLPASPPLQTSLSPAVSP 479

Query: 885  QSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAA 944
             S      P+Q  +  A H     P  +L  P   T +  SL P PS Q+P +S   P  
Sbjct: 480  LSSPLTIHPLQALSSLASHSPQA-PLSSLIMPPLETQS--SLAP-PSLQTPPASLTTPP- 534

Query: 945  VYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHP--------PQVMLLHPPQS 996
            +  +     P   T  A +T  H++T    AP P    P P        P  +   PPQ+
Sbjct: 535  LENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQA 594

Query: 997  H---GGPPQGAVPQSGVPALSASTPSPYPYIGHP--QAPLPPPGELKIVLAAT 1044
                  PP   +P   +  L+   P   P +  P  QAP  PP    +   AT
Sbjct: 595  PPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLAT 647



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 43/134 (32%), Positives = 51/134 (38%), Gaps = 30/134 (22%)

Query: 4   PQPLQQPSQP--QQPPPTQQAVA----RRPPGGTSPPNGGLP----GPLATS-------- 45
           P PLQ P  P    PP T  ++A    + PP   SPP  GLP     PLAT         
Sbjct: 566 PCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXL 625

Query: 46  -----AAPPGPPAAASPCLGPVAAAGSGLRRG-----AEGILAPQPPPPQQHQERPGAAA 95
                 APP PP  ASP L P+A               +   +P P PP Q    P A+ 
Sbjct: 626 ALPPLQAPPSPP--ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 683

Query: 96  IGSARGQSTGKGPP 109
             S       + PP
Sbjct: 684 PVSPSATPPSQAPP 697



 Score = 37.7 bits (86), Expect = 0.057
 Identities = 33/123 (26%), Positives = 43/123 (34%), Gaps = 18/123 (14%)

Query: 6   PLQQPSQPQQPPPTQQAVARRPPGGTS------------PPNGGLPGPLATSAAPPGPPA 53
           PLQ P  P   PP        P    +            PP+  +  P +  A+PP  P+
Sbjct: 629 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 688

Query: 54  AASPCLGPVAAAGSGLR----RGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109
           A  P   P + A   L+      A   ++P   PP   Q  P  AA       S    PP
Sbjct: 689 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP--QAPPPLAAPPLQVPPSPPASPP 746

Query: 110 QSP 112
            SP
Sbjct: 747 MSP 749



 Score = 37.0 bits (84), Expect = 0.097
 Identities = 39/122 (31%), Positives = 48/122 (39%), Gaps = 30/122 (24%)

Query: 13  PQQPP--PTQQAVARRPPGGTSPPNGGLPGP---LATSAAPPGPP--AAASPCLGPVAAA 65
           P  PP  PT QA  RRPP  T  P+  + GP   LA +  PP PP  + +S   GP  A 
Sbjct: 843 PPSPPASPTLQA-PRRPP--TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 899

Query: 66  GS-----------GLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVF 114
            S           G   G EG  A  PPP          A + +    +  +GP     F
Sbjct: 900 HSSSATSTPEELRGYDSGPEGGAAASPPPD---------AELAACHPAAWSRGPAPPLAF 950

Query: 115 EG 116
            G
Sbjct: 951 RG 952



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 34/112 (30%), Positives = 43/112 (38%), Gaps = 6/112 (5%)

Query: 3   KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAP-PGPPAAASPCLGP 61
           KP+ LQ    PQ  PP + A     P  +SP     P P  T A P P P  AA+P   P
Sbjct: 273 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPL--ATPSPSGTKARPVPPPDNAATPL--P 328

Query: 62  VAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP-QSP 112
                S        +  P P  P   Q  P   A   ++   +   PP Q+P
Sbjct: 329 ATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAP 380



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 32/113 (28%), Positives = 39/113 (34%), Gaps = 24/113 (21%)

Query: 2   LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLP--GPLATSAAPPGPPAAASPCL 59
           L   PLQ P  P   PP   +    PP    PP    P   P +  A+PP  P+A  P  
Sbjct: 699 LAAPPLQVPPSPPASPPMSPSAT--PPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPR 756

Query: 60  GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
            P   A   L+      + P PP               S       K PPQ+P
Sbjct: 757 VPPLLAAPPLQ------VPPSPP--------------ASLPMSPLAKPPPQAP 789



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 38/130 (29%), Positives = 48/130 (36%), Gaps = 22/130 (16%)

Query: 2   LKPQPLQQPSQPQQPPPTQQAVA---RRPPGGTSPPNGGLPGPLATS-----AAPP--GP 51
           L   PLQ P  P   PP   +     R PP   +PP    P P A+      A PP   P
Sbjct: 730 LAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAP 789

Query: 52  PAAASPCL-----GPVAAAGSG-LRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTG 105
           PA A+P L      P +  G       A   ++P   PP      P A  + +A      
Sbjct: 790 PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP------PQAPPVLAAPLLQVP 843

Query: 106 KGPPQSPVFE 115
             PP SP  +
Sbjct: 844 PSPPASPTLQ 853



 Score = 31.6 bits (70), Expect = 4.1
 Identities = 29/91 (31%), Positives = 34/91 (37%), Gaps = 13/91 (14%)

Query: 16   PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEG 75
            PPP  +  A  P   +  P      PLA   AP G P    P  GP +A G       EG
Sbjct: 926  PPPDAELAACHPAAWSRGP----APPLAFRGAP-GAPLPWPPATGPGSADGLCTIYETEG 980

Query: 76   ILAPQPPPPQQHQERPGAAAIGSARGQSTGK 106
                    P+     PGA   G + G S GK
Sbjct: 981  --------PESATPAPGALDPGPSPGTSGGK 1003



 Score = 30.4 bits (67), Expect = 9.1
 Identities = 20/73 (27%), Positives = 29/73 (39%), Gaps = 2/73 (2%)

Query: 11  SQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLR 70
           S P +  P+ +   R P   + P   GL         PP   AA  P LGP++++     
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA--PALGPLSSSPLATP 307

Query: 71  RGAEGILAPQPPP 83
             +     P PPP
Sbjct: 308 SPSGTKARPVPPP 320


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 96.7 bits (239), Expect = 1e-19
 Identities = 171/713 (23%), Positives = 245/713 (34%), Gaps = 117/713 (16%)

Query: 381  PRGPH--HLDNSSPGP-GSEARGINGGPSRMSPKAQRPLRGAKTL-----SSPSNRPSGE 432
            P+G H   +    PGP   EA+ +     ++ P+ + PL     L      SP + P  E
Sbjct: 396  PKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEE 455

Query: 433  TSVPPPPAVGRMYPPRSPKSAAPAP----ISASCPEPPIGSAVPTSSASIPVTSSVSDPG 488
            +   PPP   R+ PP     A+P P    +S    E P+      S  S P  SS   P 
Sbjct: 456  SPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSP- 514

Query: 489  VGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKF 548
                SP SP     P+   E     P    E   L+      P  +        EEL   
Sbjct: 515  -LEESPLSPPEESPPSPALETPLSPPP---EASPLS------PPFEESPLSPPPEELPTS 564

Query: 549  GAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGL--------LTSEPMGSPVSSKT 600
                  + S  PE S    PP   +E P     E   L        L+  P  SP+S   
Sbjct: 565  PPPEASRLSPPPEESPMSPPP---EESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPP 621

Query: 601  ES--VSDKEDKPPLAPSGGTEGPEQPPP--------PCPSQTGSPPVGLIKGEDKDEGPV 650
            E+  +S   +  P++P    E P  PPP        P  S+   PP         +E P 
Sbjct: 622  EASRLSPPPEDSPMSPP-PEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPT 680

Query: 651  AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGL-YSPQ 709
            +   + S L+P   E +PT P         +P SP P   S  S+P+  +    L   PQ
Sbjct: 681  SPPPEASRLSP-PPEDSPTSP-----PPEDSPASPPPE-DSLMSLPLEESPLLPLPEEPQ 733

Query: 710  YISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQH-QPASAPPMM 768
                    H+ P  + P + P P               +  L PQ  + H  P    P +
Sbjct: 734  LCPRSEGPHLSPRPEEPHLSPRP--------------EEPHLSPQAEEPHLSPQPEEPCL 779

Query: 769  QAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQP-MAHYPSQPVFAPMLQS------- 820
               A    P ++      ++   P++    P   +P ++  P +P  +P  +        
Sbjct: 780  --CAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQS 837

Query: 821  -----NPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQP 875
                 +PR   S   P+       P  P  E+P  +       +  P     L     +P
Sbjct: 838  EEPCLSPRPEESHLSPEL---EKPPLSPRPEKPPEEPGQCPAPEELP-----LFPPPGEP 889

Query: 876  ATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQP--QQNLYHPGALTGTPPSLPP----- 928
            + +P   +P        P+     + P   SG+P     L  P  L   PP L P     
Sbjct: 890  SLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPL---PPPLSPIITAA 946

Query: 929  GPSAQSPQSSFPQPAAVYAIHHQQLPHGF----TNMAHVTQAHVQTGITAAP---PPHPG 981
             P A SP      P         + P       T ++   +A+        P   PP PG
Sbjct: 947  APPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPG 1006

Query: 982  APHPPQVMLLH---PPQ-----SHGGPPQGAVP-QSGVPALSASTPSPYPYIG 1025
            +P  P   +L    PPQ      H   PQ + P Q   PAL  S PSP   IG
Sbjct: 1007 SPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIG 1059



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 141/594 (23%), Positives = 202/594 (34%), Gaps = 98/594 (16%)

Query: 422  LSSPSNRPSGETSVPPPP-AVGRMYPPRSP-----KSAAPAPISASCP---EPPIGSAVP 472
            ++  ++RP+    +PP P A+G   P  +P         PA +S S     +PP GS   
Sbjct: 2093 IARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPG 2152

Query: 473  TSSAS---------IPVTSSVSDP-GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQE 522
              S           +P      DP G+    P  P+   AP       +   G   +P  
Sbjct: 2153 PDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPT-GAPAQPPM 2211

Query: 523  LARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRI----LKEEPK- 577
            L   A   PG        Q  E             S+P+  L P  P +    + E P  
Sbjct: 2212 LG--ASSRPGAG------QPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGV 2263

Query: 578  GKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPV 637
            G  K  + LL+  P G   S K   V  KE+    +PS G        PP      SP  
Sbjct: 2264 GGGKASEPLLSPPPFGE--SRKALEVK-KEELGASSPSYG--------PPNLGFVDSPSS 2312

Query: 638  GLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPV 697
            G   G  + + P    V K+ L P A +  P  P L +      P  P P     PS P 
Sbjct: 2313 GTHLGGLELKTP---DVFKAPLTPRASQVEPQSPGLGLR-----PQEPPPAQALAPSPP- 2363

Query: 698  LTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQ---GKYRGAKGSLPPQ 754
                   ++ P   SY       P    PQ  P     ++P +      +     S P  
Sbjct: 2364 ---SHPDIFRPG--SYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPAS-PQS 2417

Query: 755  RSDQHQPASAPPMMQAAAAAGPPLVAATP-YSSYIPYNPQQFPGQPAMMQPMA--HYPSQ 811
            +S    P +  P+   A    P     TP + S  PY+    P +P    P A  H P +
Sbjct: 2418 QSSSQSPLTPRPLSAEAFCPSP----VTPRFQSPDPYSRP--PSRPQSRDPFAPLHKPPR 2471

Query: 812  PVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAE--------QPTPQALYATVHQSYPH 863
            P   P +      L   S       ++ P  P+ E        QP P  + +    ++  
Sbjct: 2472 PQ-PPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQP-PNFVRSPGTGAFVG 2529

Query: 864  HATQLHAHQPQPATTPTGSQPQSQHAAPSP--VQHQAGQAPHLGSGQPQQNLYHPGALTG 921
              + +    PQ    P+   P  Q   P P  +    G  P LG  +PQ   Y       
Sbjct: 2530 TPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLG--KPQSTNYTVATGNF 2587

Query: 922  TPPSLPPGPSAQS-----------PQSSFPQPAAVYAIHHQQLPHGFTNMAHVT 964
             P   P GPS+ S           P S  P PA   ++ +  L HG +  + +T
Sbjct: 2588 HPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPY--LSHGASQRSGIT 2639



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 162/801 (20%), Positives = 262/801 (32%), Gaps = 142/801 (17%)

Query: 308  QYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIP-----LPQRVREGPRG 362
            +YR +   +    + ++++HSAV      +    L    G+ +P      PQ    G  G
Sbjct: 3594 EYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAG 3653

Query: 363  GVRCSSSRGGRPGLSSLP-----------------------PRG---PHHLDNSSPGPGS 396
            G+R +      PG    P                       P G   P +L   S GP S
Sbjct: 3654 GLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDS 3713

Query: 397  ---EARGINGGPSRMS-----------PKAQRPLRGAKTLSSPSNR-PSGETSVPPPPAV 441
               + R +     RM             + Q+ L G   +     + P  +T+    P  
Sbjct: 3714 RLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKP 3773

Query: 442  GRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISL 501
              + PP S +      +S   P+ P G   P   A +           G++ P  P   +
Sbjct: 3774 QGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVL------QQQHPGALGPQGPHRQV 3827

Query: 502  APTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPS---- 557
              T  + LS+ +    L  Q    +  ++   Q +Q++ Q ++         LQ S    
Sbjct: 3828 LMTQSRVLSSPQ----LAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSH 3883

Query: 558  -SSPENSLDPFPP-RILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPS 615
               P+ S  P    + L+++ + ++++       + +      + + +  ++ +  L   
Sbjct: 3884 SGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQ 3943

Query: 616  GGTE----------GPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKE 665
               +            +Q       Q     +GL+        P  +Q ++  L P    
Sbjct: 3944 QQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGM-- 4001

Query: 666  FNPTKPLL--------------------SVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGL 705
              P KPL                     +V+ + S+  + GP TH    + + T  +S  
Sbjct: 4002 --PAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMA 4059

Query: 706  YSPQYISYIPQIHMGPAVQAPQMYPYPVSNSV--------PGQQGK-----YRGAKGSLP 752
              P  +   P +     +   Q  P P  +S+        PGQQ +     +    GS  
Sbjct: 4060 TEPGEVK--PSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHG 4117

Query: 753  PQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHY--PS 810
               S     AS+ P + A      P V+       +  N    P QP + +PM +   P 
Sbjct: 4118 QLGSGSSSEASSVPHLLAQ-----PSVSLGDQPGSMTQNLLG-PQQPMLERPMQNNTGPQ 4171

Query: 811  QPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHA 870
             P   P+LQS   +   G  P      +  Q   A+ P  + L     Q       Q   
Sbjct: 4172 PPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQL 4231

Query: 871  HQPQPAT-TPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPG 929
             Q Q    TP   +P +Q    SP+Q   G  P LG          PG  TG    L  G
Sbjct: 4232 QQSQAVRQTPPYQEPGTQ---TSPLQGLLGCQPQLGG--------FPGPQTGPLQELGAG 4280

Query: 930  PSAQSPQ---------SSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAA-PPPH 979
            P  Q P          S+ P    V+       P      + +     Q    A  PP H
Sbjct: 4281 PRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTH 4340

Query: 980  PGAPHPPQVMLLHPPQSHGGP 1000
            PG P  PQ   L PP     P
Sbjct: 4341 PGTP-KPQGPTLEPPPGRVSP 4360



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 112/505 (22%), Positives = 157/505 (31%), Gaps = 108/505 (21%)

Query: 341  SLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPH--------------- 385
            SL   E   +PLP+  +  PR      S R   P LS  P   PH               
Sbjct: 717  SLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEE-PHLSPQAEEPHLSPQPE 775

Query: 386  -----------HLDNSSPGP--GSEARGINGGPS----RMSPKAQRPLRGAKTLSSPSNR 428
                       HL   + GP    +   ++  P      +SP  + P    +   S  + 
Sbjct: 776  EPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSP 835

Query: 429  PSGETSVPPPPAVGRM-----YPPRSPKSAAPAPISASCPEPPIGSAVP----TSSASIP 479
             S E  + P P    +      PP SP+   P      CP P      P     S + + 
Sbjct: 836  QSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLL 895

Query: 480  VTSSVSDPGVGSISPASPKISLAPTDVKELSTK-EPGRTLEPQELARIAGKVPGLQNEQK 538
               ++S+PG   +SP   ++ L+P+    LS +  P   L P     I    P       
Sbjct: 896  GEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPP------ 949

Query: 539  RFQLEELRKFGAQFKLQPSSSPENSL--------------------DPFPPRILKEEPKG 578
               L  L +    F  +  S PE+ L                    +P PP IL   P  
Sbjct: 950  --ALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGS 1007

Query: 579  KEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSP--P 636
                   +L  EP+    S   +     ++ PP   S         PP  P    SP  P
Sbjct: 1008 PVGPASPIL-MEPLPPQCSPLLQHSLVPQNSPPSQCS---------PPALPLSVPSPLSP 1057

Query: 637  VGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNP--TKPLLSVNKSTSTPT-SPGPRTHSTP 693
            +G + G   DE  + E   +    P      P  T PL S     S P  SP P      
Sbjct: 1058 IGKVVGV-SDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFS 1116

Query: 694  SIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQ-QGKYRGAKGSLP 752
             +   TA   G                  + AP   P P     PG    + +G+   L 
Sbjct: 1117 GLGEDTAPLDG------------------IDAPGSQPEP--GQTPGSLASELKGSPVLLD 1156

Query: 753  PQRSDQHQPASAPPMMQAAAAAGPP 777
            P+      P    P  +  A  G P
Sbjct: 1157 PEELAPVTPMEVYPECKQTAGQGSP 1181



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 162/717 (22%), Positives = 240/717 (33%), Gaps = 148/717 (20%)

Query: 377  SSLPPRGPHHL---DNSSPGP---GSEARGINGGPSRMSPKAQRPLRGAKTLS-SPSNRP 429
            +S P  GP +L   D+ S G    G E +  +   + ++P+A +    +  L   P   P
Sbjct: 2294 ASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPP 2353

Query: 430  SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGV 489
              +   P PP+   ++ P S       P     P+PP     P S  ++P  S  SDP  
Sbjct: 2354 PAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPP----PPESCCALPPRSLPSDPF- 2408

Query: 490  GSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFG 549
             S  PASP+         + S++ P   L P+ L+  A     +     RFQ  +     
Sbjct: 2409 -SRVPASPQ--------SQSSSQSP---LTPRPLSAEAFCPSPVT---PRFQSPDPYS-- 2451

Query: 550  AQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD---GLLTSEPMGS---PVSSKTESV 603
                 +P S P+ S DPF P  L + P+ +  EV    G L    +G+   P +      
Sbjct: 2452 -----RPPSRPQ-SRDPFAP--LHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPA 2503

Query: 604  SDKEDKPPLAP---------SGGTEGPEQP--------------PPPCPSQTGSPPVGLI 640
             +   K P            +G   G   P               PP P     PP G+ 
Sbjct: 2504 GELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGI- 2562

Query: 641  KGEDKDEGPVAEQVKKSTLNPNAKEFNPT-KPLLSVNKSTST--------PTSPGPRTHS 691
                   GP   + + +        F+P+  PL   + ST          P S  P    
Sbjct: 2563 -NSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAP 2621

Query: 692  TPSIPVLTAG---QSGLYSPQYISYIPQIHMG--------PAVQAPQMYPYPVS------ 734
              S+P L+ G   +SG+ SP      P   MG        P  Q P M     +      
Sbjct: 2622 DGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQR 2681

Query: 735  ----------------NSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPL 778
                            N++  ++     A G++ P  S   +P+S  P  +  +    P 
Sbjct: 2682 QRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSS--PAFEQLSRGQTPF 2739

Query: 779  VAATPYSSYIPYNPQQFPGQ---PAMM--QPMAHYPSQPVFAPMLQSNPRMLTSGSHPQA 833
                  SS +   P +  G    P           P  P     +  N R L  GS  QA
Sbjct: 2740 AGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGS--QA 2797

Query: 834  IVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQ-SQHAAPS 892
                +   YP +  P  Q       Q     AT +       A  P+   P+  + A  S
Sbjct: 2798 FYQRAP--YPGS-LPLQQQQQQLWQQQQATAATSMRF--AMSARFPSTPGPELGRQALGS 2852

Query: 893  PVQHQAGQAPHLGSGQPQQNLYHPGALT--------GTPPSLPPGPSAQSPQSSFPQPAA 944
            P+   + + P  G G+P      P            G  P   P P    PQ   P+   
Sbjct: 2853 PLAGISTRLP--GPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQR--PRFYP 2908

Query: 945  VYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQV-MLLHPPQSHGGP 1000
            V    H+  P G   +A          ++  PP  P AP  P++   LHP     GP
Sbjct: 2909 VSEDPHRLAPEGLRGLA----------VSGLPPQKPSAPPAPELNNSLHPTPHTKGP 2955



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 155/739 (20%), Positives = 244/739 (33%), Gaps = 113/739 (15%)

Query: 361  RGGVRCSSSRGGRPGLSSLP---------PRGPHHLDNSSPGPGSEARGINGGPSRMSP- 410
            +G + C    GG PG  + P         P+GP  L      PG+ + G   GP   +P 
Sbjct: 4254 QGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAP---PGALSTGPVLGPVHPTPP 4310

Query: 411  --KAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIG 468
                Q P R ++ L SPS++   E  +PP         P +PK   P        EPP G
Sbjct: 4311 PSSPQEPKRPSQ-LPSPSSQLPTEAQLPPT-------HPGTPKPQGPT------LEPPPG 4356

Query: 469  SAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAG 528
               P   A+  +  ++   G+G   P  P  +LA T   E S+  PG       L ++ G
Sbjct: 4357 RVSP---AAAQLADTLFSKGLG---PWDPPDNLAETQKPEQSSLVPG------HLDQVNG 4404

Query: 529  KV--PGLQNEQKRFQLEELRKFGAQ-FKLQPSSSP------ENSLDPFPPR------ILK 573
            +V     Q   K+   EE    GAQ  K + +  P       N L    PR      +L+
Sbjct: 4405 QVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQ 4464

Query: 574  EEPKGKEKEVDGLLTSEPMGSPVSSKTES-VSDKEDKPPLAPSGGTEG----PEQPPPPC 628
            +  + K  ++     SE + + ++   +S ++  E K    PS   +     P  P P  
Sbjct: 4465 KLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPLTPKPKR 4524

Query: 629  PSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPR 688
              +     V   K   K++G  A +     L         T+P ++ N S   P   G  
Sbjct: 4525 VQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSGCP 4584

Query: 689  THSTPSIPVLTAGQSGLYSPQYIS-YIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGA 747
             +    +       +    P Y S  + + ++      P   P       P    + +  
Sbjct: 4585 VNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSSLP-----PTPPPSVQQKMV 4639

Query: 748  KGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAH 807
             G  P +   +H   +A       A      V +    + +P  P        M      
Sbjct: 4640 NGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDED- 4698

Query: 808  YPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYP-----------SAEQPT----PQA 852
                         +P  +   S P++I+    P++P            A  P     P+A
Sbjct: 4699 -----------SDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALSPVIPLIPRA 4747

Query: 853  LYATVHQSYPHHATQLHAHQPQPATT---PTGSQPQ-----SQHAAPSPVQHQAGQAPHL 904
                   + P+ A  L      P TT     GS+       S  AA +        A  L
Sbjct: 4748 SIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELL 4807

Query: 905  GSGQPQQNLY-----HPGALTGTPP----SLPPGPSAQSPQSSFPQPAAVYAIHHQQLPH 955
                P  N Y        A  GT P    +  PG   +  +   P     +      +  
Sbjct: 4808 SMKIP--NSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLP 4865

Query: 956  GFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSA 1015
            G+T  + +    +    + AP P     +   V  L   Q    PP+   P     A S 
Sbjct: 4866 GYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSP 4925

Query: 1016 STPSPYPYIGHPQAPLPPP 1034
            ++P   P +  P  PL  P
Sbjct: 4926 ASPPTEPLVELPTEPLAEP 4944



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 82/341 (24%), Positives = 113/341 (33%), Gaps = 47/341 (13%)

Query: 721  PAVQAPQMY---PYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPP 777
            P   AP ++   P   +       G  +   GS+P   S        PP + A   +  P
Sbjct: 2117 PPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDP 2176

Query: 778  LVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQA---- 833
               A  Y    P  P+ FP  P    P   YPS P  AP   + P ML + S P A    
Sbjct: 2177 FGLAPAY----PLEPR-FPTAPPTYPP---YPS-PTGAP---AQPPMLGASSRPGAGQPG 2224

Query: 834  IVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLH-------AHQPQPATTPTGSQPQS 886
               ++ P  P  +  TP         S  + A           A +P  +  P G   ++
Sbjct: 2225 EFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKA 2284

Query: 887  QHAAPSPVQHQAGQ--APHLGSGQPQQNLYHPGALTGTPPS-----LPPGPSAQSPQS-- 937
                   +   +     P+LG      +  H G L    P      L P  S   PQS  
Sbjct: 2285 LEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPG 2344

Query: 938  -----SFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLH 992
                   P PA   A      P  F   ++ T  + Q  +T  P P P     P+     
Sbjct: 2345 LGLRPQEPPPAQALAPSPPSHPDIFRPGSY-TDPYAQPPLTPRPQPPP-----PESCCAL 2398

Query: 993  PPQSHGGPPQGAVPQSGVPALSASTP-SPYPYIGHPQAPLP 1032
            PP+S    P   VP S     S+ +P +P P       P P
Sbjct: 2399 PPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSP 2439



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 33/112 (29%), Positives = 43/112 (38%), Gaps = 22/112 (19%)

Query: 1    MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
            +L  + LQQ    +Q PP Q+      PG  + P  GL G        PGP        G
Sbjct: 4225 LLMQRQLQQSQAVRQTPPYQE------PGTQTSPLQGLLGCQPQLGGFPGPQT------G 4272

Query: 61   PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
            P+   G+G          P+P  P +    PGA + G   G      PP SP
Sbjct: 4273 PLQELGAG----------PRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSP 4314



 Score = 34.3 bits (77), Expect = 0.63
 Identities = 32/120 (26%), Positives = 43/120 (35%), Gaps = 10/120 (8%)

Query: 2   LKPQPLQQPSQ--PQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCL 59
           L+  PL  P +  P  PPP     +       SPP    P P   +  P  PP  ASP  
Sbjct: 489 LEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALET--PLSPPPEASPLS 546

Query: 60  GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS----PVFE 115
            P     S L    E +    PP   +    P  + +     +S    PP++    P FE
Sbjct: 547 PPFEE--SPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFE 604



 Score = 33.9 bits (76), Expect = 0.82
 Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 21/97 (21%)

Query: 2    LKPQ-PLQQPSQPQQPPPTQQAVARRPP--GGTSPPNGGLPGPLATSAAPPG----PPAA 54
            L+P+ P   P+ P  P PT      +PP  G +S P  G PG   T+  PPG     P+ 
Sbjct: 2185 LEPRFPTAPPTYPPYPSPT--GAPAQPPMLGASSRPGAGQPGEFHTT--PPGTPRHQPST 2240

Query: 55   ASPCLGP----------VAAAGSGLRRGAEGILAPQP 81
              P L P            + G G  + +E +L+P P
Sbjct: 2241 PDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPP 2277



 Score = 33.9 bits (76), Expect = 0.82
 Identities = 85/391 (21%), Positives = 128/391 (32%), Gaps = 66/391 (16%)

Query: 561  ENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEG 620
            +N++DP    +  E  +G      G     P+    + ++ +    E KP L+       
Sbjct: 4026 QNTVDP---AVSSEATEGPSTHQGG-----PLAIGTTPESMATEPGEVKPSLSGDSQLLL 4077

Query: 621  PEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQV---KKSTLNPNAKEFNPTKPLLSVNK 677
             +  P P PS     P   + G+ + +  +           L   +     + P L    
Sbjct: 4078 VQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQP 4137

Query: 678  STSTPTSPGPRTHST--PSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSN 735
            S S    PG  T +   P  P+L         PQ          GP +Q+ Q  P     
Sbjct: 4138 SVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQ------PPKPGPVLQSGQGLPGVGIM 4191

Query: 736  SVPGQ-QGKYRGAKGSLP------PQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYI 788
               GQ + + +G     P      PQ+  Q Q       +Q + A     V  TP     
Sbjct: 4192 PTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQA-----VRQTP----- 4241

Query: 789  PYNPQQFPG-QPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQ 847
               P Q PG Q + +Q +     Q    P  Q+ P         Q + +   PQ P    
Sbjct: 4242 ---PYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPL--------QELGAGPRPQGPP-RL 4289

Query: 848  PTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSG 907
            P P    +T     P H T        P ++P   +  SQ  +PS       Q P     
Sbjct: 4290 PAPPGALSTGPVLGPVHPTP-------PPSSPQEPKRPSQLPSPSSQLPTEAQLPPT--- 4339

Query: 908  QPQQNLYHPGALTGTPPSLPPGPSAQSPQSS 938
                   HPG      P+L P P   SP ++
Sbjct: 4340 -------HPGTPKPQGPTLEPPPGRVSPAAA 4363



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 34/125 (27%), Positives = 50/125 (40%), Gaps = 16/125 (12%)

Query: 2   LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
           L P+P + P +P Q P  ++     PPG   P    L G  A S   PG P   SP    
Sbjct: 860 LSPRPEKPPEEPGQCPAPEELPLFPPPG--EPSLSPLLGEPALS--EPGEP-PLSPLPEE 914

Query: 62  VAAAGSGLRRGAEGILAPQPPPPQ-----QHQERPGAAAIG------SARGQSTGKGPPQ 110
           +  + SG    +  ++ P P PP           P  + +G       A+G S  + P  
Sbjct: 915 LPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLA 974

Query: 111 SPVFE 115
           +P+ E
Sbjct: 975 APILE 979



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 76/339 (22%), Positives = 105/339 (30%), Gaps = 52/339 (15%)

Query: 740  QQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQP 799
            QQ + +   G +  Q+  Q  P      +Q   A GP      P SS+     QQ   QP
Sbjct: 3740 QQQQQQHLLGQVAIQQQQQQGPG-----VQTNQALGPKPQGLMPPSSHQGLLVQQLSPQP 3794

Query: 800  AMMQPMAHYPSQPVFAPMLQSNPRML-TSGSHPQAIVSSS----TPQYPSAEQPTPQALY 854
                     P+Q   A + Q +P  L   G H Q +++ S    +PQ     Q       
Sbjct: 3795 PQGPQGMLGPAQ--VAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRL 3852

Query: 855  ATVHQ----------------SYPHHATQLHAHQPQPATTPTGS--------QPQSQHAA 890
             T  Q                S+   +   H+ QP+ +  P GS        Q Q Q   
Sbjct: 3853 VTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQL 3912

Query: 891  PSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHH 950
                Q Q  Q   L   Q QQ              L      Q  Q    Q    +    
Sbjct: 3913 QQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQ--QQQQQLQQQQQQQQQQFQQQQ 3970

Query: 951  QQLPHGFTNMAHV---------TQAHVQTGITAAPPPHPGAPHP--PQVMLLHPPQSHGG 999
            QQ   G  N +            Q  +  G+ A P  H  +P    P ++L    Q+   
Sbjct: 3971 QQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVD 4030

Query: 1000 PPQGAVPQSGVPALSASTPSPYPYIGHPQAPLPPPGELK 1038
            P   AV        S     P      P++    PGE+K
Sbjct: 4031 P---AVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVK 4066



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 38/130 (29%), Positives = 46/130 (35%), Gaps = 28/130 (21%)

Query: 1    MLKPQPLQQPSQPQQPPP-------TQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPA 53
            +++PQP  QPS  Q  PP        QQ       GG S    G  G  ++S A   P  
Sbjct: 4077 LVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGS---HGQLGSGSSSEASSVPHL 4133

Query: 54   AASPCLGPVAAAGS-----------GLRRGAEGILAPQPPPP----QQHQERPGAA---A 95
             A P +      GS            L R  +    PQPP P    Q  Q  PG      
Sbjct: 4134 LAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPT 4193

Query: 96   IGSARGQSTG 105
            +G  R Q  G
Sbjct: 4194 VGQLRAQLQG 4203



 Score = 31.6 bits (70), Expect = 4.1
 Identities = 22/74 (29%), Positives = 27/74 (36%), Gaps = 1/74 (1%)

Query: 16   PPPTQQAVARRPPGGTSPPNGGLPG-PLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAE 74
            PP     V  + P G +P     P  P A    PP P    +P   P+  A S    G  
Sbjct: 2164 PPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQP 2223

Query: 75   GILAPQPPPPQQHQ 88
            G     PP   +HQ
Sbjct: 2224 GEFHTTPPGTPRHQ 2237



 Score = 31.2 bits (69), Expect = 5.3
 Identities = 34/124 (27%), Positives = 44/124 (35%), Gaps = 23/124 (18%)

Query: 3    KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPV 62
            K Q  QQ  Q QQ    Q A+ ++   G        PG     A  P P     P     
Sbjct: 3733 KLQQQQQQQQQQQHLLGQVAIQQQQQQG--------PGVQTNQALGPKPQGLMPPS---- 3780

Query: 63   AAAGSGLRRGAEGILAPQ--PPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
                       +G+L  Q  P PPQ  Q   G A +   + Q  G   PQ P  + +   
Sbjct: 3781 ---------SHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQ 3831

Query: 121  SRML 124
            SR+L
Sbjct: 3832 SRVL 3835



 Score = 31.2 bits (69), Expect = 5.3
 Identities = 31/112 (27%), Positives = 42/112 (37%), Gaps = 22/112 (19%)

Query: 834  IVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSP 893
            I+S    + P+ E PT          SY ++ + L   Q   A  P    P     APSP
Sbjct: 4875 ILSLLKQESPAPEPPT--------QHSYTYNVSNLDVRQLS-APPPEEPSPPPSPLAPSP 4925

Query: 894  VQHQAGQAPHLGSGQPQQNLYH-PGALTGTPPSLPPGPSAQSPQSSFPQPAA 944
                        +  P + L   P      PP   P P A SP+S+ P+P A
Sbjct: 4926 ------------ASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRA 4965



 Score = 31.2 bits (69), Expect = 5.3
 Identities = 20/61 (32%), Positives = 24/61 (39%), Gaps = 4/61 (6%)

Query: 974  AAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQAPLPP 1033
            +APPP    P PP   L   P S    P   +P    P      PSP P    P++  P 
Sbjct: 4907 SAPPPEE--PSPPPSPLAPSPASPPTEPLVELPTE--PLAEPPVPSPLPLASSPESARPK 4962

Query: 1034 P 1034
            P
Sbjct: 4963 P 4963



 Score = 30.8 bits (68), Expect = 7.0
 Identities = 42/184 (22%), Positives = 66/184 (35%), Gaps = 37/184 (20%)

Query: 873  PQPATTPTGS----------QPQSQHAA------PSPVQHQA---GQAPHLGSGQPQQNL 913
            P+P  TPT            QP+  H        P P+Q +A   G+A      Q +  L
Sbjct: 375  PEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPL 434

Query: 914  YHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHG-FTNMAHVTQAHVQTGI 972
                 L   P   P  P  +   +S P  A+  +   ++LP        H+++   ++ +
Sbjct: 435  NEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPL 494

Query: 973  TAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQAPLP 1032
            +  P   P +P P         +S   PP+ + P    PAL              + PL 
Sbjct: 495  SPPPEESPLSPPPESSPFSPLEESPLSPPEESPPS---PAL--------------ETPLS 537

Query: 1033 PPGE 1036
            PP E
Sbjct: 538  PPPE 541



 Score = 30.4 bits (67), Expect = 9.1
 Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 11/93 (11%)

Query: 5   QPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAA 64
           +PL++   P  PPP +  ++  PP  +SP +     PL+     P  PA  +P L P   
Sbjct: 487 RPLEE--SPLSPPPEESPLS--PPPESSPFSPLEESPLSPPEESPPSPALETP-LSPPPE 541

Query: 65  AGSGLRRGAEGILAPQP------PPPQQHQERP 91
           A        E  L+P P      PPP+  +  P
Sbjct: 542 ASPLSPPFEESPLSPPPEELPTSPPPEASRLSP 574


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
          Length = 816

 Score = 94.4 bits (233), Expect = 5e-19
 Identities = 172/720 (23%), Positives = 242/720 (33%), Gaps = 113/720 (15%)

Query: 357  REGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGING-GPSRMSPKAQRP 415
            R+  + G    +     PGL  L PR P       P   +  R +   G     P A+R 
Sbjct: 5    RDKAKAGAAARTPAARAPGL--LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERA 62

Query: 416  LRGAKTLSSPSNRP-SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTS 474
              G    + P + P +G T    PPA GR       K+ +P P+S+  P    G+  P  
Sbjct: 63   -GGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSS--PGRASGTTRP-- 117

Query: 475  SASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELAR-IAGKVPGL 533
                           G +     +IS   T  +  +T+ P R+       R  +G  PG 
Sbjct: 118  ---------------GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGT 162

Query: 534  QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593
             +          R  G +  L     P  S  P PP    E P+          T+EP  
Sbjct: 163  PSPA---MARRSRAAGTEVGLP---RPAPSARPRPPT---EGPRKSVSSASEHSTTEP-- 211

Query: 594  SPVSSKTESVSDKEDKPPLAPSGGTEGP-EQPPPPCPSQTGSPPVGLIKGEDKDEGPVAE 652
            SP + +  S      +P       +  P   P    PS  G+P       + K +G   +
Sbjct: 212  SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG--LQ 269

Query: 653  QVKKSTLNPNAKEFNPTK-PLLSVNKSTSTPTSPG-----PRTHSTPSIPVLTAGQS--G 704
             ++   + P  K+  P   PL S   +T +P++P      P   + PS P     Q+   
Sbjct: 270  ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTS 329

Query: 705  LYSPQYI---SYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQP 761
            L SP      S++P   + P    P   P  ++                LPP ++    P
Sbjct: 330  LGSPTLQATHSFLPSPPLSPLATPPPQAPPALA----------------LPPLQAPPSPP 373

Query: 762  ASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSN 821
            AS PP+   A  +     A   +    P++P   P   A   P A  P  P   P  Q+ 
Sbjct: 374  AS-PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 432

Query: 822  PRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTG 881
            P +            +S P  PSA  P PQA         P  A  L   +P P   P  
Sbjct: 433  PSLAAPPLQVPPSPPASPPMSPSA-TPPPQA-------PPPLAAPPLQLAKPPPQAPPAL 484

Query: 882  SQPQSQHAAPSPVQHQAGQAPHLGSGQ-PQQNLYHPGALTGTPPSLPP---GPSAQSPQS 937
            + P  Q A PSP     GQAP   S   P   L  P      PP  PP    P  Q P  
Sbjct: 485  ATPPLQ-ALPSPPASFPGQAPFSPSASLPMSPLATP------PPQAPPVLAAPLLQVP-- 535

Query: 938  SFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHP----------------- 980
              P P A   +   + P        V+   +   +   PPP P                 
Sbjct: 536  --PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHS 593

Query: 981  -GAPHPPQVMLLHPPQSHGG-----PPQGAVPQSGVPALSASTPSPYPYIGHPQAPLPPP 1034
              A   P+ +  +     GG     PP   +      A S     P  + G P APLP P
Sbjct: 594  SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWP 653



 Score = 39.7 bits (91), Expect = 0.015
 Identities = 33/123 (26%), Positives = 44/123 (35%), Gaps = 22/123 (17%)

Query: 6   PLQQPSQPQQPPPTQQAVARRPPGGTS------------PPNGGLPGPLATSAAPPGPPA 53
           PLQ P  P   PP        P    +            PP+  +  P +  A+PP  P+
Sbjct: 365 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 424

Query: 54  AASPCLGPVAAAGSGLRRGAEGILAPQPP--PPQQHQERPGAAAIG--SARGQSTGKGPP 109
           A  P   P + A   L+      + P PP  PP      P   A    +A      K PP
Sbjct: 425 ATPPSQAPPSLAAPPLQ------VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 478

Query: 110 QSP 112
           Q+P
Sbjct: 479 QAP 481



 Score = 39.7 bits (91), Expect = 0.015
 Identities = 63/290 (21%), Positives = 92/290 (31%), Gaps = 29/290 (10%)

Query: 392 PGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPK 451
           P P  +A         +SP A  P +   +L++P  +        PP +     PP++P 
Sbjct: 405 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 464

Query: 452 SAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISP---------ASPKISLA 502
             A  P+  + P P    A+ T       +   S PG    SP         A+P     
Sbjct: 465 PLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 524

Query: 503 PTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN 562
           P     L    P     P   A      PG        +L      G      PS SP +
Sbjct: 525 PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP--PPPPSRSPSS 582

Query: 563 SLD-----------PFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPP 611
           +L               P  L+    G E    G   S P  + +++   +   +   PP
Sbjct: 583 TLSGPDLAGHSSSATSTPEELRGYDSGPE---GGAAASPPPDAELAACHPAAWSRGPAPP 639

Query: 612 LAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNP 661
           LA      G    P P P  TG      +    + EGP +       L+P
Sbjct: 640 LA----FRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDP 685



 Score = 38.1 bits (87), Expect = 0.044
 Identities = 35/110 (31%), Positives = 46/110 (41%), Gaps = 22/110 (20%)

Query: 10  PSQPQQPPPTQQAVARRPPGGTSPPNGGLP--GPLATS-AAPPGPPAAASPCLGPVAAAG 66
           P+ P QP P +   A RPP  T P     P  GPL++S  A P P A  SP   P     
Sbjct: 257 PAHPSQPKP-KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPP----- 310

Query: 67  SGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK---GPPQSPV 113
                  + + +P   PP Q        ++GS   Q+T      PP SP+
Sbjct: 311 -----SLQTLPSPPATPPSQ-----ATTSLGSPTLQATHSFLPSPPLSPL 350



 Score = 37.0 bits (84), Expect = 0.097
 Identities = 34/122 (27%), Positives = 48/122 (39%), Gaps = 15/122 (12%)

Query: 3   KPQPLQQPSQPQQPPPTQQAVAR---------RPPGGTSPPNGGLPGPLATSAAPPG-PP 52
           KP+ LQ    PQ  PP + A              P  ++PP+   P  L T  +PP  PP
Sbjct: 264 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPP 323

Query: 53  AAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARG-QSTGKGPPQS 111
           + A+  LG      +     +  +     PPPQ     P A A+   +   S    PP S
Sbjct: 324 SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ----APPALALPPLQAPPSPPASPPLS 379

Query: 112 PV 113
           P+
Sbjct: 380 PL 381



 Score = 37.0 bits (84), Expect = 0.097
 Identities = 39/122 (31%), Positives = 48/122 (39%), Gaps = 30/122 (24%)

Query: 13  PQQPP--PTQQAVARRPPGGTSPPNGGLPGP---LATSAAPPGPP--AAASPCLGPVAAA 65
           P  PP  PT QA  RRPP  T  P+  + GP   LA +  PP PP  + +S   GP  A 
Sbjct: 535 PPSPPASPTLQA-PRRPP--TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 591

Query: 66  GS-----------GLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVF 114
            S           G   G EG  A  PPP          A + +    +  +GP     F
Sbjct: 592 HSSSATSTPEELRGYDSGPEGGAAASPPPD---------AELAACHPAAWSRGPAPPLAF 642

Query: 115 EG 116
            G
Sbjct: 643 RG 644



 Score = 33.9 bits (76), Expect = 0.82
 Identities = 36/125 (28%), Positives = 43/125 (34%), Gaps = 27/125 (21%)

Query: 4   PQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLAT---------SAAPPGPPAA 54
           P PL  P      PP Q      PP   +PP   LP P A+         SA+ P  P A
Sbjct: 463 PPPLAAPPLQLAKPPPQA-----PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 517

Query: 55  ASPCLGPVAAAGSGLRRGAEGILAPQPP--PPQQHQER-----PGAAAIGSARGQSTGKG 107
             P   P   A   L+      + P PP  P  Q   R     P  +  G     +   G
Sbjct: 518 TPPPQAPPVLAAPLLQ------VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 571

Query: 108 PPQSP 112
           PP  P
Sbjct: 572 PPPPP 576



 Score = 33.1 bits (74), Expect = 1.4
 Identities = 39/143 (27%), Positives = 55/143 (38%), Gaps = 34/143 (23%)

Query: 1   MLKPQPLQQPSQPQQPPPTQQ----------AVARRP--------PGGTSPPNGGLPGPL 42
           +L P+P   P  P+ PPP             AV R+P         G T P +    GP 
Sbjct: 24  LLTPRP---PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT 80

Query: 43  ATSAAPPG-----PPAAASPCLGPVAAAG--SGLRR----GAEG--ILAPQPPPPQQHQE 89
            TS  P        P A +   GPV++ G  SG  R    G +G  I A +     +  E
Sbjct: 81  RTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE 140

Query: 90  RPGAAAIGSARGQSTGKGPPQSP 112
            P  +A+ +   + T    P +P
Sbjct: 141 APKRSALSAGARRDTSGPTPGTP 163



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 30/100 (30%), Positives = 36/100 (36%), Gaps = 12/100 (12%)

Query: 10  PSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGL 69
           P  P   PP Q      PP    PP   L  P +  A+PP  P A      P A A   L
Sbjct: 346 PLSPLATPPPQ-----APPALALPP---LQAPPSPPASPPLSPLATPSPQAPNALAVHLL 397

Query: 70  RRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109
               +   +P P PP Q    P A+   S       + PP
Sbjct: 398 ----QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 433



 Score = 31.6 bits (70), Expect = 4.1
 Identities = 33/119 (27%), Positives = 43/119 (36%), Gaps = 21/119 (17%)

Query: 6   PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPG-P---PAAASPCLGP 61
           P+Q P  P   PP   +     P   +PP+   P PL    +PP  P   P+A  P   P
Sbjct: 408 PVQAPFSPPASPPVSPSAT---PPSQAPPSLAAP-PLQVPPSPPASPPMSPSATPPPQAP 463

Query: 62  VAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGP-------PQSPV 113
              A   L+      LA  PP        P   A+ S      G+ P       P SP+
Sbjct: 464 PPLAAPPLQ------LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 516



 Score = 31.6 bits (70), Expect = 4.1
 Identities = 29/91 (31%), Positives = 34/91 (37%), Gaps = 13/91 (14%)

Query: 16  PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEG 75
           PPP  +  A  P   +  P      PLA   AP G P    P  GP +A G       EG
Sbjct: 618 PPPDAELAACHPAAWSRGP----APPLAFRGAP-GAPLPWPPATGPGSADGLCTIYETEG 672

Query: 76  ILAPQPPPPQQHQERPGAAAIGSARGQSTGK 106
                   P+     PGA   G + G S GK
Sbjct: 673 --------PESATPAPGALDPGPSPGTSGGK 695



 Score = 30.4 bits (67), Expect = 9.1
 Identities = 31/126 (24%), Positives = 45/126 (35%), Gaps = 21/126 (16%)

Query: 6   PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGP--------PAAASP 57
           P   P++  +PP + +     P   TSP     PG  A+    PGP         A  + 
Sbjct: 75  PRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPG-RASGTTRPGPLGQKGLRISAEETV 133

Query: 58  CLGPV------AAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIG------SARGQSTG 105
             G        +A  +G RR   G     P P    + R     +G      SAR +   
Sbjct: 134 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 193

Query: 106 KGPPQS 111
           +GP +S
Sbjct: 194 EGPRKS 199


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 855

 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 177/731 (24%), Positives = 240/731 (32%), Gaps = 167/731 (22%)

Query: 357  REGP-RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRP 415
            R GP R     S +   RP  S    R P    N+SPGP S   G   G +R  P  Q+ 
Sbjct: 76   RAGPTRSAGTSSRNPASRPPASGRGERAPP-AKNTSPGPVSSP-GRASGTTRPGPLGQKG 133

Query: 416  LR---------GAKT-------LSSPSNRP-SGETSVPPPPAVGRMYPPRSPKSAAPAPI 458
            LR         G  T       LS+ + R  SG T   P PA+ R       +   P P 
Sbjct: 134  LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 193

Query: 459  SASCPEPPI-GSAVPTSSASIPVTSSVS-------DPGVGSISPASPKISLAPTDVKELS 510
             ++ P PP  G     SSAS   T+  S         G G   PAS  +S + T +   +
Sbjct: 194  PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253

Query: 511  TKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPR 570
               P         AR   + P   ++ K   L+ LR                     PP+
Sbjct: 254  RSGPS--------ARGTPRAPAHPSQPKPKGLQALR---------------------PPQ 284

Query: 571  ILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPS 630
            +    P+       G L+S P+ +P                 +PS   +   Q PP  P+
Sbjct: 285  VTP--PRKDAAPALGPLSSSPLATP-----------------SPSAALQS--QAPPTLPA 323

Query: 631  QTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTH 690
               S  +            +A  +  +  +P+A     T P        S P +P  +  
Sbjct: 324  TPHSSSLTC---------QLATPLPLAPPSPSAPPSLQTLP--------SPPATPPSQAT 366

Query: 691  STPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGS 750
            ++   P L A  S L SP          + P    P   P  ++                
Sbjct: 367  TSLGSPTLQATHSFLPSPP---------LSPLATPPPQAPPALA---------------- 401

Query: 751  LPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPS 810
            LPP ++    PAS PP+   A  +     A   +    P++P   P   A   P A  P 
Sbjct: 402  LPPLQAPPSPPAS-PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 460

Query: 811  QPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHA 870
             P   P  Q+ P +            +S P  PSA  P PQA         P  A  L  
Sbjct: 461  SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA-TPPPQA-------PPPLAAPPLQL 512

Query: 871  HQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQ-PQQNLYHPGALTGTPPSLPP- 928
             +P P   P  + P  Q A PSP     GQAP   S   P   L  P      PP  PP 
Sbjct: 513  AKPPPQAPPALATPPLQ-ALPSPPASFPGQAPFSPSASLPMSPLATP------PPQAPPV 565

Query: 929  --GPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHP------ 980
               P  Q P    P P A   +   + P        V+   +   +   PPP P      
Sbjct: 566  LAAPLLQVP----PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS 621

Query: 981  ------------GAPHPPQVMLLHPPQSHGG-----PPQGAVPQSGVPALSASTPSPYPY 1023
                         A   P+ +  +     GG     PP   +      A S     P  +
Sbjct: 622  TLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAF 681

Query: 1024 IGHPQAPLPPP 1034
             G P APLP P
Sbjct: 682  RGAPGAPLPWP 692



 Score = 39.7 bits (91), Expect = 0.015
 Identities = 33/123 (26%), Positives = 44/123 (35%), Gaps = 22/123 (17%)

Query: 6   PLQQPSQPQQPPPTQQAVARRPPGGTS------------PPNGGLPGPLATSAAPPGPPA 53
           PLQ P  P   PP        P    +            PP+  +  P +  A+PP  P+
Sbjct: 404 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 463

Query: 54  AASPCLGPVAAAGSGLRRGAEGILAPQPP--PPQQHQERPGAAAIG--SARGQSTGKGPP 109
           A  P   P + A   L+      + P PP  PP      P   A    +A      K PP
Sbjct: 464 ATPPSQAPPSLAAPPLQ------VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 517

Query: 110 QSP 112
           Q+P
Sbjct: 518 QAP 520



 Score = 39.7 bits (91), Expect = 0.015
 Identities = 63/290 (21%), Positives = 92/290 (31%), Gaps = 29/290 (10%)

Query: 392 PGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPK 451
           P P  +A         +SP A  P +   +L++P  +        PP +     PP++P 
Sbjct: 444 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 503

Query: 452 SAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISP---------ASPKISLA 502
             A  P+  + P P    A+ T       +   S PG    SP         A+P     
Sbjct: 504 PLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 563

Query: 503 PTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN 562
           P     L    P     P   A      PG        +L      G      PS SP +
Sbjct: 564 PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP--PPPPSRSPSS 621

Query: 563 SLD-----------PFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPP 611
           +L               P  L+    G E    G   S P  + +++   +   +   PP
Sbjct: 622 TLSGPDLAGHSSSATSTPEELRGYDSGPE---GGAAASPPPDAELAACHPAAWSRGPAPP 678

Query: 612 LAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNP 661
           LA      G    P P P  TG      +    + EGP +       L+P
Sbjct: 679 LA----FRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDP 724



 Score = 37.0 bits (84), Expect = 0.097
 Identities = 39/122 (31%), Positives = 48/122 (39%), Gaps = 30/122 (24%)

Query: 13  PQQPP--PTQQAVARRPPGGTSPPNGGLPGP---LATSAAPPGPP--AAASPCLGPVAAA 65
           P  PP  PT QA  RRPP  T  P+  + GP   LA +  PP PP  + +S   GP  A 
Sbjct: 574 PPSPPASPTLQA-PRRPP--TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 630

Query: 66  GS-----------GLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVF 114
            S           G   G EG  A  PPP          A + +    +  +GP     F
Sbjct: 631 HSSSATSTPEELRGYDSGPEGGAAASPPPD---------AELAACHPAAWSRGPAPPLAF 681

Query: 115 EG 116
            G
Sbjct: 682 RG 683



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 35/124 (28%), Positives = 47/124 (37%), Gaps = 20/124 (16%)

Query: 3   KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAA-------- 54
           KP+ LQ    PQ  PP + A     P  +SP     P     S APP  PA         
Sbjct: 273 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTC 332

Query: 55  --ASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK---GPP 109
             A+P   P+A          + + +P   PP Q        ++GS   Q+T      PP
Sbjct: 333 QLATPL--PLAPPSPSAPPSLQTLPSPPATPPSQ-----ATTSLGSPTLQATHSFLPSPP 385

Query: 110 QSPV 113
            SP+
Sbjct: 386 LSPL 389



 Score = 33.9 bits (76), Expect = 0.82
 Identities = 36/125 (28%), Positives = 43/125 (34%), Gaps = 27/125 (21%)

Query: 4   PQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLAT---------SAAPPGPPAA 54
           P PL  P      PP Q      PP   +PP   LP P A+         SA+ P  P A
Sbjct: 502 PPPLAAPPLQLAKPPPQA-----PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 556

Query: 55  ASPCLGPVAAAGSGLRRGAEGILAPQPP--PPQQHQER-----PGAAAIGSARGQSTGKG 107
             P   P   A   L+      + P PP  P  Q   R     P  +  G     +   G
Sbjct: 557 TPPPQAPPVLAAPLLQ------VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 610

Query: 108 PPQSP 112
           PP  P
Sbjct: 611 PPPPP 615



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 30/100 (30%), Positives = 36/100 (36%), Gaps = 12/100 (12%)

Query: 10  PSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGL 69
           P  P   PP Q      PP    PP   L  P +  A+PP  P A      P A A   L
Sbjct: 385 PLSPLATPPPQ-----APPALALPP---LQAPPSPPASPPLSPLATPSPQAPNALAVHLL 436

Query: 70  RRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109
               +   +P P PP Q    P A+   S       + PP
Sbjct: 437 ----QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 472



 Score = 31.6 bits (70), Expect = 4.1
 Identities = 33/119 (27%), Positives = 43/119 (36%), Gaps = 21/119 (17%)

Query: 6   PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPG-P---PAAASPCLGP 61
           P+Q P  P   PP   +     P   +PP+   P PL    +PP  P   P+A  P   P
Sbjct: 447 PVQAPFSPPASPPVSPSAT---PPSQAPPSLAAP-PLQVPPSPPASPPMSPSATPPPQAP 502

Query: 62  VAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGP-------PQSPV 113
              A   L+      LA  PP        P   A+ S      G+ P       P SP+
Sbjct: 503 PPLAAPPLQ------LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 555



 Score = 31.6 bits (70), Expect = 4.1
 Identities = 29/91 (31%), Positives = 34/91 (37%), Gaps = 13/91 (14%)

Query: 16  PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEG 75
           PPP  +  A  P   +  P      PLA   AP G P    P  GP +A G       EG
Sbjct: 657 PPPDAELAACHPAAWSRGP----APPLAFRGAP-GAPLPWPPATGPGSADGLCTIYETEG 711

Query: 76  ILAPQPPPPQQHQERPGAAAIGSARGQSTGK 106
                   P+     PGA   G + G S GK
Sbjct: 712 --------PESATPAPGALDPGPSPGTSGGK 734


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 81.6 bits (200), Expect = 3e-15
 Identities = 139/524 (26%), Positives = 188/524 (35%), Gaps = 87/524 (16%)

Query: 561  ENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTES-VSDKEDKPPLAPSGGTE 619
            E  +DP PP + K      ++E DGL     M +  S  + S +     K P +P G T 
Sbjct: 546  EKPVDP-PPFMFKPV----KEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTS 600

Query: 620  GPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKST 679
               +      S   SP        D      AE VKKS      +  +P K      +  
Sbjct: 601  PINEDIRS--SGRNSPSAASTSSNDSK----AETVKKSAKKVKEEASSPLKSNKRQREKV 654

Query: 680  STPTSPGPRTHST---------PSIPVLTAGQS---------GLYSPQYISYIPQIHMGP 721
            ++ T    RT S          P+ P    G+S         G   P+ I    +    P
Sbjct: 655  ASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNR-STSP 713

Query: 722  AVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAA 781
            ++ +PQ       +S   QQ   +    +L         P+SAPP        GP     
Sbjct: 714  SIPSPQDNESDSDSSA--QQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP----- 766

Query: 782  TPYSSYIPYNPQQFP-GQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
            TP ++ +P  PQ  P    A  QP A  P+ PV    +Q  P +     HPQ   S   P
Sbjct: 767  TPSATAVP--PQGSPTASQAPNQPQA--PTAPVPHTHIQQAPAL-----HPQRPPSPHPP 817

Query: 841  QYPSAEQPTPQALYATVHQSYPHHATQ-LHAHQPQPATTPTGSQPQSQHAAPS-----PV 894
             +PS   P      +    S P HA   LH   P P      + P  QH  P      P 
Sbjct: 818  PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGP-PGPHSLQAGPLLQHPGPPQPFGLPP 876

Query: 895  QHQAGQAPHLGSGQ----PQQNLYHPGALTGT----PPS---LPPGPSAQ--------SP 935
            Q   GQAP LG+      P  +L  P + +      PP    LPP P A         +P
Sbjct: 877  QASQGQAP-LGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP 935

Query: 936  QSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQ 995
                P P A     H   P  F+  A++        +++    HP + HPP + L+  PQ
Sbjct: 936  IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM--PQ 993

Query: 996  SHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQ------APLPP 1033
            S   P   A P    P L+ S   P P   HP       AP PP
Sbjct: 994  SQPLPSSPAQP----PGLTQSQNLPPPPASHPPTGLHQVAPQPP 1033



 Score = 77.8 bits (190), Expect = 5e-14
 Identities = 137/558 (24%), Positives = 189/558 (33%), Gaps = 116/558 (20%)

Query: 543  EELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTES 602
            E++R  G      PS++  +S D     + K   K KE+    L +++     V+S TE 
Sbjct: 604  EDIRSSGRN---SPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEE 660

Query: 603  VSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPN 662
                  K        T+  E   P  PS+         +GE  D   V           N
Sbjct: 661  ADRTSSKK-------TKTQEISRPNSPSEG--------EGESSDSRSV-----------N 694

Query: 663  AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIP-----VLTAGQSGLYSPQYISYIPQI 717
             +  +  K +   N+STS P+ P P+ + + S       +L A    L +P  ++  P  
Sbjct: 695  DEGSSDPKDIDQDNRSTS-PSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSS 753

Query: 718  HMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPP 777
                  Q P   P P + +VP Q        GS    ++     A   P+        P 
Sbjct: 754  APPGTPQLPTPGPTPSATAVPPQ--------GSPTASQAPNQPQAPTAPVPHTHIQQAPA 805

Query: 778  LVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSS 837
            L    P S + P +P   P     +QP+     QP  AP     P        P ++ + 
Sbjct: 806  LHPQRPPSPHPPPHPSPHPP----LQPLTGSAGQPS-APSHAQPPLHGQGPPGPHSLQAG 860

Query: 838  STPQYPSAEQP---TPQA------LYATVHQSYPHHATQLHAHQ---------------P 873
               Q+P   QP    PQA      L  +   +YPH + QL A Q               P
Sbjct: 861  PLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPP 920

Query: 874  QPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQP---QQNLYHPGAL-------TGTP 923
             P   P    P +      P        PHL    P     NL  P AL       T  P
Sbjct: 921  APLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHP 980

Query: 924  PSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFT---NMAHVTQAHVQTGITAAPPPHP 980
            PS  P P    PQS  P P++         P G T   N+     +H  TG+    P  P
Sbjct: 981  PSAHPPPLQLMPQSQ-PLPSS------PAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPP 1033

Query: 981  GAPH------PPQV------MLLHPPQSHG----GPPQGAVPQSGVPALSASTPSPYPYI 1024
             A H      PP +          PP   G     P  GA    G  A  +S P P   I
Sbjct: 1034 FAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQI 1093

Query: 1025 --------GHPQAPLPPP 1034
                      P++P PPP
Sbjct: 1094 KEEALDDAEEPESPPPPP 1111



 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 133/610 (21%), Positives = 211/610 (34%), Gaps = 109/610 (17%)

Query: 430  SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVS--DP 487
            SG+ S+    + G M   RS +   PA  S      PI   + +S  + P  +S S  D 
Sbjct: 567  SGKHSMRTRRSRGSMSTLRSGRKKQPA--SPDGRTSPINEDIRSSGRNSPSAASTSSNDS 624

Query: 488  GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547
               ++  ++ K+    +   + + ++  +     E A         +   K+ + +E+ +
Sbjct: 625  KAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEAD--------RTSSKKTKTQEISR 676

Query: 548  FGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD--GLLTSEPMGSPVSSKTESVSD 605
                    P+S  E   +    R + +E     K++D     TS  + SP  ++++S S 
Sbjct: 677  --------PNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSS 728

Query: 606  KEDK-----PPL--APSGGTEGPEQPPP---------PCPSQTGSPPVGLIKGEDKDEGP 649
             + +     PP   AP+G T  P   PP         P PS T  PP G          P
Sbjct: 729  AQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQP 788

Query: 650  VAEQV--------KKSTLNPNAKEF-------NPTKPLLSVNKSTSTPTSPGPRTHSTPS 694
             A           +   L+P            +P  PL  +  S   P++P   +H+ P 
Sbjct: 789  QAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP---SHAQP- 844

Query: 695  IPVLTAGQSGLYS------------PQYISYIPQIHMGPA---VQAPQMYPYPVSNSVPG 739
             P+   G  G +S            PQ     PQ   G A         YP+  S  +P 
Sbjct: 845  -PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH-TSLQLPA 902

Query: 740  QQGKYRGAKG-------------------------SLPPQRSDQHQPASAPPMMQAAAAA 774
             Q   +  +                           LP  ++ +H P  + P   +  A 
Sbjct: 903  SQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNAN 962

Query: 775  GPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAH-YPSQPVFAPML-QSNPRMLTSGSHPQ 832
             PP  A  P SS   ++P      P  + P +   PS P   P L QS        SHP 
Sbjct: 963  LPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPP 1022

Query: 833  AIVSSSTPQYPSAEQP-TPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAP 891
              +    PQ P A+ P  P         + P  +T        PA   T +QP    AA 
Sbjct: 1023 TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP-------PAGPGTSAQPPCSGAAA 1075

Query: 892  SPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQ 951
            S      G +  L + Q ++          +PP  P  PS +      P  A+  A  ++
Sbjct: 1076 SGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYK 1135

Query: 952  QLPHGFTNMA 961
             L  G+ + A
Sbjct: 1136 HLDRGYNSCA 1145



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 135/639 (21%), Positives = 209/639 (32%), Gaps = 114/639 (17%)

Query: 374  PGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSP--SNRPSG 431
            P L  L     HH  ++ P P          PS  SP     L  ++ L  P  S+ P+G
Sbjct: 967  PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPS--SPAQPPGLTQSQNLPPPPASHPPTG 1024

Query: 432  ETSVPP-PPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPG-- 488
               V P PP     + P  P    P P   S   PP G   P +SA  P + + +  G  
Sbjct: 1025 LHQVAPQPPFAQHPFVPGGPPPITP-PTCPSTSTPPAG---PGTSAQPPCSGAAASGGSI 1080

Query: 489  VGSISPASPKISLAPTDVKELSTKE----PGRTLEPQ-----------ELARIAGKVPGL 533
             G  S   P + +    + +    E    P R+  P+           + AR    +   
Sbjct: 1081 AGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRG 1140

Query: 534  QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593
             N   R  L  +   G++   +   + E +      +  +E  + KEKE +     E   
Sbjct: 1141 YNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERERER 1200

Query: 594  SPVSSKTESVSDKEDK--PPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVA 651
                +   S S  E +   P     G   P   PPP       P +G             
Sbjct: 1201 EAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIG------------- 1247

Query: 652  EQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP--TSPGPRTHS-----TPSIPVLTAGQSG 704
                            P  P L      + P   SP  R H       P+ P+L     G
Sbjct: 1248 ----------------PDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPG 1291

Query: 705  LYSPQYISYIPQIHMGPAVQAPQMYPYPV-SNSVPGQQGKYRGAKG-SLPPQRSDQHQPA 762
            LY+           + P ++  ++    +    +  ++ + R   G  + P   D   PA
Sbjct: 1292 LYN-----------VDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPA 1340

Query: 763  SAPP--MMQAAAAAGPPLVAATPYSSYIP-YNP---QQFPGQPAMMQPMAHYPSQPVFAP 816
            + P     + +A   PP     P++S+ P  NP   ++       ++P   YP +     
Sbjct: 1341 ANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAER 1400

Query: 817  MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQP- 875
            +       LTS    +  + + TP                 H  + H  + LH HQ  P 
Sbjct: 1401 IHAERMASLTSDPLARLQMFNVTPH----------------HHQHSHIHSHLHLHQQDPL 1444

Query: 876  ---ATTPTGSQPQSQHAAP--SPVQHQAGQAPHLGSGQP---QQNLYHPGALTGTPPSL- 926
               +  P         A P  +   +  G  P+   GQP    + L HP   T  P  L 
Sbjct: 1445 HQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLP 1504

Query: 927  ----PPGPSAQSPQSSFPQPAAVYAI-HHQQLPHGFTNM 960
                PP  +A   Q+   Q A +  +   QQ  HG  +M
Sbjct: 1505 GAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHGHPHM 1543



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 39/134 (29%), Positives = 51/134 (38%), Gaps = 32/134 (23%)

Query: 2    LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNG-----------------GLPGPL-- 42
            L PQ    PS P QPP   Q+    PP  + PP G                 G P P+  
Sbjct: 990  LMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITP 1049

Query: 43   ----ATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGS 98
                +TS  P GP  +A P     AA+G  +  G+       P P  Q +E     A+  
Sbjct: 1050 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSS-----CPLPTVQIKEE----ALDD 1100

Query: 99   ARGQSTGKGPPQSP 112
            A    +   PP+SP
Sbjct: 1101 AEEPESPPPPPRSP 1114



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 92/374 (24%), Positives = 125/374 (33%), Gaps = 82/374 (21%)

Query: 371  GGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS 430
            G  P  SS PP  P      +PGP   A  +             P +G+ T S   N+P 
Sbjct: 746  GVTPAPSSAPPGTPQL---PTPGPTPSATAV-------------PPQGSPTASQAPNQPQ 789

Query: 431  GETSVPPPPAVGR---MYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDP 487
              T+  P   + +   ++P R P   +P P     P PP+     T SA  P   S + P
Sbjct: 790  APTAPVPHTHIQQAPALHPQRPP---SPHPPPHPSPHPPLQPL--TGSAGQPSAPSHAQP 844

Query: 488  GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547
             +    P  P    A   ++     +P   L PQ      G+ P   +    +    L+ 
Sbjct: 845  PLHGQGPPGPHSLQAGPLLQHPGPPQP-FGLPPQ---ASQGQAPLGTSPAAAYPHTSLQL 900

Query: 548  FGAQFKLQPSSSP-ENSLDPFP-------------------PRILKEEPK---GKEKEVD 584
              +Q  LQ    P E  L P P                   P+  K  P         ++
Sbjct: 901  PASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 960

Query: 585  GLLTSEPMGSPVSSKTESVSDKEDKPPL--------------APSGGTEGPEQPPPPCPS 630
              L   P   P+SS +         PPL               P G T+    PPPP   
Sbjct: 961  ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP--- 1017

Query: 631  QTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTH 690
                PP GL   +   + P A+        P      PT P      STSTP + GP T 
Sbjct: 1018 -ASHPPTGL--HQVAPQPPFAQHPFVPGGPPPITP--PTCP------STSTPPA-GPGTS 1065

Query: 691  STPSIPVLTAGQSG 704
            + P  P   A  SG
Sbjct: 1066 AQP--PCSGAAASG 1077



 Score = 38.9 bits (89), Expect = 0.026
 Identities = 38/118 (32%), Positives = 46/118 (38%), Gaps = 10/118 (8%)

Query: 4   PQPLQQPSQPQQP----PPT--QQAVA---RRPPGGTSPPNGGLPGPLATSAAPPGPPAA 54
           P   Q P+QPQ P    P T  QQA A   +RPP    PP+     PL       G P+A
Sbjct: 779 PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSA 838

Query: 55  ASPCLGPVAAAG-SGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111
            S    P+   G  G      G L   P PPQ     P A+   +  G S     P +
Sbjct: 839 PSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHT 896



 Score = 37.0 bits (84), Expect = 0.097
 Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 6/110 (5%)

Query: 6   PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAA 65
           P  Q ++       QQ + +  P     P G  P P   S+APPG P   +P   P A A
Sbjct: 716 PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP---SSAPPGTPQLPTPGPTPSATA 772

Query: 66  --GSGLRRGAEGILAPQ-PPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
               G    ++    PQ P  P  H     A A+   R  S    P  SP
Sbjct: 773 VPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP 822



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 30/111 (27%), Positives = 38/111 (34%), Gaps = 7/111 (6%)

Query: 9   QPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSG 68
           QP   Q P     A +  PPG    P  G P P AT+  P G P A+     P A     
Sbjct: 737 QPPALQAPTGVTPAPSSAPPGTPQLPTPG-PTPSATAVPPQGSPTASQAPNQPQAPTAPV 795

Query: 69  LRRGAEGILA------PQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPV 113
                +   A      P P PP      P    +  + GQ +     Q P+
Sbjct: 796 PHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL 846



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 33/111 (29%), Positives = 42/111 (37%), Gaps = 15/111 (13%)

Query: 2    LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
            L P PL  P   + PP T       P     PP+   P P + +A  P PPA     L P
Sbjct: 918  LPPAPLAMP-HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPA-----LKP 971

Query: 62   VAAAGSGLRRGAEGILAPQPPPPQ---QHQERPGAAAIGSARGQSTGKGPP 109
            +++  +     A       PPP Q   Q Q  P + A      QS    PP
Sbjct: 972  LSSLSTHHPPSA------HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 1016


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 81.6 bits (200), Expect = 3e-15
 Identities = 139/524 (26%), Positives = 188/524 (35%), Gaps = 87/524 (16%)

Query: 561  ENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTES-VSDKEDKPPLAPSGGTE 619
            E  +DP PP + K      ++E DGL     M +  S  + S +     K P +P G T 
Sbjct: 546  EKPVDP-PPFMFKPV----KEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTS 600

Query: 620  GPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKST 679
               +      S   SP        D      AE VKKS      +  +P K      +  
Sbjct: 601  PINEDIRS--SGRNSPSAASTSSNDSK----AETVKKSAKKVKEEASSPLKSNKRQREKV 654

Query: 680  STPTSPGPRTHST---------PSIPVLTAGQS---------GLYSPQYISYIPQIHMGP 721
            ++ T    RT S          P+ P    G+S         G   P+ I    +    P
Sbjct: 655  ASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNR-STSP 713

Query: 722  AVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAA 781
            ++ +PQ       +S   QQ   +    +L         P+SAPP        GP     
Sbjct: 714  SIPSPQDNESDSDSSA--QQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP----- 766

Query: 782  TPYSSYIPYNPQQFP-GQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
            TP ++ +P  PQ  P    A  QP A  P+ PV    +Q  P +     HPQ   S   P
Sbjct: 767  TPSATAVP--PQGSPTASQAPNQPQA--PTAPVPHTHIQQAPAL-----HPQRPPSPHPP 817

Query: 841  QYPSAEQPTPQALYATVHQSYPHHATQ-LHAHQPQPATTPTGSQPQSQHAAPS-----PV 894
             +PS   P      +    S P HA   LH   P P      + P  QH  P      P 
Sbjct: 818  PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGP-PGPHSLQAGPLLQHPGPPQPFGLPP 876

Query: 895  QHQAGQAPHLGSGQ----PQQNLYHPGALTGT----PPS---LPPGPSAQ--------SP 935
            Q   GQAP LG+      P  +L  P + +      PP    LPP P A         +P
Sbjct: 877  QASQGQAP-LGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP 935

Query: 936  QSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQ 995
                P P A     H   P  F+  A++        +++    HP + HPP + L+  PQ
Sbjct: 936  IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM--PQ 993

Query: 996  SHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQ------APLPP 1033
            S   P   A P    P L+ S   P P   HP       AP PP
Sbjct: 994  SQPLPSSPAQP----PGLTQSQNLPPPPASHPPTGLHQVAPQPP 1033



 Score = 77.8 bits (190), Expect = 5e-14
 Identities = 137/558 (24%), Positives = 189/558 (33%), Gaps = 116/558 (20%)

Query: 543  EELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTES 602
            E++R  G      PS++  +S D     + K   K KE+    L +++     V+S TE 
Sbjct: 604  EDIRSSGRN---SPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEE 660

Query: 603  VSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPN 662
                  K        T+  E   P  PS+         +GE  D   V           N
Sbjct: 661  ADRTSSKK-------TKTQEISRPNSPSEG--------EGESSDSRSV-----------N 694

Query: 663  AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIP-----VLTAGQSGLYSPQYISYIPQI 717
             +  +  K +   N+STS P+ P P+ + + S       +L A    L +P  ++  P  
Sbjct: 695  DEGSSDPKDIDQDNRSTS-PSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSS 753

Query: 718  HMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPP 777
                  Q P   P P + +VP Q        GS    ++     A   P+        P 
Sbjct: 754  APPGTPQLPTPGPTPSATAVPPQ--------GSPTASQAPNQPQAPTAPVPHTHIQQAPA 805

Query: 778  LVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSS 837
            L    P S + P +P   P     +QP+     QP  AP     P        P ++ + 
Sbjct: 806  LHPQRPPSPHPPPHPSPHPP----LQPLTGSAGQPS-APSHAQPPLHGQGPPGPHSLQAG 860

Query: 838  STPQYPSAEQP---TPQA------LYATVHQSYPHHATQLHAHQ---------------P 873
               Q+P   QP    PQA      L  +   +YPH + QL A Q               P
Sbjct: 861  PLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPP 920

Query: 874  QPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQP---QQNLYHPGAL-------TGTP 923
             P   P    P +      P        PHL    P     NL  P AL       T  P
Sbjct: 921  APLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHP 980

Query: 924  PSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFT---NMAHVTQAHVQTGITAAPPPHP 980
            PS  P P    PQS  P P++         P G T   N+     +H  TG+    P  P
Sbjct: 981  PSAHPPPLQLMPQSQ-PLPSS------PAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPP 1033

Query: 981  GAPH------PPQV------MLLHPPQSHG----GPPQGAVPQSGVPALSASTPSPYPYI 1024
             A H      PP +          PP   G     P  GA    G  A  +S P P   I
Sbjct: 1034 FAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQI 1093

Query: 1025 --------GHPQAPLPPP 1034
                      P++P PPP
Sbjct: 1094 KEEALDDAEEPESPPPPP 1111



 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 133/610 (21%), Positives = 211/610 (34%), Gaps = 109/610 (17%)

Query: 430  SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVS--DP 487
            SG+ S+    + G M   RS +   PA  S      PI   + +S  + P  +S S  D 
Sbjct: 567  SGKHSMRTRRSRGSMSTLRSGRKKQPA--SPDGRTSPINEDIRSSGRNSPSAASTSSNDS 624

Query: 488  GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547
               ++  ++ K+    +   + + ++  +     E A         +   K+ + +E+ +
Sbjct: 625  KAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEAD--------RTSSKKTKTQEISR 676

Query: 548  FGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD--GLLTSEPMGSPVSSKTESVSD 605
                    P+S  E   +    R + +E     K++D     TS  + SP  ++++S S 
Sbjct: 677  --------PNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSS 728

Query: 606  KEDK-----PPL--APSGGTEGPEQPPP---------PCPSQTGSPPVGLIKGEDKDEGP 649
             + +     PP   AP+G T  P   PP         P PS T  PP G          P
Sbjct: 729  AQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQP 788

Query: 650  VAEQV--------KKSTLNPNAKEF-------NPTKPLLSVNKSTSTPTSPGPRTHSTPS 694
             A           +   L+P            +P  PL  +  S   P++P   +H+ P 
Sbjct: 789  QAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP---SHAQP- 844

Query: 695  IPVLTAGQSGLYS------------PQYISYIPQIHMGPA---VQAPQMYPYPVSNSVPG 739
             P+   G  G +S            PQ     PQ   G A         YP+  S  +P 
Sbjct: 845  -PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH-TSLQLPA 902

Query: 740  QQGKYRGAKG-------------------------SLPPQRSDQHQPASAPPMMQAAAAA 774
             Q   +  +                           LP  ++ +H P  + P   +  A 
Sbjct: 903  SQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNAN 962

Query: 775  GPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAH-YPSQPVFAPML-QSNPRMLTSGSHPQ 832
             PP  A  P SS   ++P      P  + P +   PS P   P L QS        SHP 
Sbjct: 963  LPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPP 1022

Query: 833  AIVSSSTPQYPSAEQP-TPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAP 891
              +    PQ P A+ P  P         + P  +T        PA   T +QP    AA 
Sbjct: 1023 TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP-------PAGPGTSAQPPCSGAAA 1075

Query: 892  SPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQ 951
            S      G +  L + Q ++          +PP  P  PS +      P  A+  A  ++
Sbjct: 1076 SGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYK 1135

Query: 952  QLPHGFTNMA 961
             L  G+ + A
Sbjct: 1136 HLDRGYNSCA 1145



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 135/639 (21%), Positives = 209/639 (32%), Gaps = 114/639 (17%)

Query: 374  PGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSP--SNRPSG 431
            P L  L     HH  ++ P P          PS  SP     L  ++ L  P  S+ P+G
Sbjct: 967  PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPS--SPAQPPGLTQSQNLPPPPASHPPTG 1024

Query: 432  ETSVPP-PPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPG-- 488
               V P PP     + P  P    P P   S   PP G   P +SA  P + + +  G  
Sbjct: 1025 LHQVAPQPPFAQHPFVPGGPPPITP-PTCPSTSTPPAG---PGTSAQPPCSGAAASGGSI 1080

Query: 489  VGSISPASPKISLAPTDVKELSTKE----PGRTLEPQ-----------ELARIAGKVPGL 533
             G  S   P + +    + +    E    P R+  P+           + AR    +   
Sbjct: 1081 AGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRG 1140

Query: 534  QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593
             N   R  L  +   G++   +   + E +      +  +E  + KEKE +     E   
Sbjct: 1141 YNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERERER 1200

Query: 594  SPVSSKTESVSDKEDK--PPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVA 651
                +   S S  E +   P     G   P   PPP       P +G             
Sbjct: 1201 EAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIG------------- 1247

Query: 652  EQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP--TSPGPRTHS-----TPSIPVLTAGQSG 704
                            P  P L      + P   SP  R H       P+ P+L     G
Sbjct: 1248 ----------------PDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPG 1291

Query: 705  LYSPQYISYIPQIHMGPAVQAPQMYPYPV-SNSVPGQQGKYRGAKG-SLPPQRSDQHQPA 762
            LY+           + P ++  ++    +    +  ++ + R   G  + P   D   PA
Sbjct: 1292 LYN-----------VDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPA 1340

Query: 763  SAPP--MMQAAAAAGPPLVAATPYSSYIP-YNP---QQFPGQPAMMQPMAHYPSQPVFAP 816
            + P     + +A   PP     P++S+ P  NP   ++       ++P   YP +     
Sbjct: 1341 ANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAER 1400

Query: 817  MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQP- 875
            +       LTS    +  + + TP                 H  + H  + LH HQ  P 
Sbjct: 1401 IHAERMASLTSDPLARLQMFNVTPH----------------HHQHSHIHSHLHLHQQDPL 1444

Query: 876  ---ATTPTGSQPQSQHAAP--SPVQHQAGQAPHLGSGQP---QQNLYHPGALTGTPPSL- 926
               +  P         A P  +   +  G  P+   GQP    + L HP   T  P  L 
Sbjct: 1445 HQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLP 1504

Query: 927  ----PPGPSAQSPQSSFPQPAAVYAI-HHQQLPHGFTNM 960
                PP  +A   Q+   Q A +  +   QQ  HG  +M
Sbjct: 1505 GAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHGHPHM 1543



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 39/134 (29%), Positives = 51/134 (38%), Gaps = 32/134 (23%)

Query: 2    LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNG-----------------GLPGPL-- 42
            L PQ    PS P QPP   Q+    PP  + PP G                 G P P+  
Sbjct: 990  LMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITP 1049

Query: 43   ----ATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGS 98
                +TS  P GP  +A P     AA+G  +  G+       P P  Q +E     A+  
Sbjct: 1050 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSS-----CPLPTVQIKEE----ALDD 1100

Query: 99   ARGQSTGKGPPQSP 112
            A    +   PP+SP
Sbjct: 1101 AEEPESPPPPPRSP 1114



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 92/374 (24%), Positives = 125/374 (33%), Gaps = 82/374 (21%)

Query: 371  GGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS 430
            G  P  SS PP  P      +PGP   A  +             P +G+ T S   N+P 
Sbjct: 746  GVTPAPSSAPPGTPQL---PTPGPTPSATAV-------------PPQGSPTASQAPNQPQ 789

Query: 431  GETSVPPPPAVGR---MYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDP 487
              T+  P   + +   ++P R P   +P P     P PP+     T SA  P   S + P
Sbjct: 790  APTAPVPHTHIQQAPALHPQRPP---SPHPPPHPSPHPPLQPL--TGSAGQPSAPSHAQP 844

Query: 488  GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547
             +    P  P    A   ++     +P   L PQ      G+ P   +    +    L+ 
Sbjct: 845  PLHGQGPPGPHSLQAGPLLQHPGPPQP-FGLPPQ---ASQGQAPLGTSPAAAYPHTSLQL 900

Query: 548  FGAQFKLQPSSSP-ENSLDPFP-------------------PRILKEEPK---GKEKEVD 584
              +Q  LQ    P E  L P P                   P+  K  P         ++
Sbjct: 901  PASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 960

Query: 585  GLLTSEPMGSPVSSKTESVSDKEDKPPL--------------APSGGTEGPEQPPPPCPS 630
              L   P   P+SS +         PPL               P G T+    PPPP   
Sbjct: 961  ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP--- 1017

Query: 631  QTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTH 690
                PP GL   +   + P A+        P      PT P      STSTP + GP T 
Sbjct: 1018 -ASHPPTGL--HQVAPQPPFAQHPFVPGGPPPITP--PTCP------STSTPPA-GPGTS 1065

Query: 691  STPSIPVLTAGQSG 704
            + P  P   A  SG
Sbjct: 1066 AQP--PCSGAAASG 1077



 Score = 38.9 bits (89), Expect = 0.026
 Identities = 38/118 (32%), Positives = 46/118 (38%), Gaps = 10/118 (8%)

Query: 4   PQPLQQPSQPQQP----PPT--QQAVA---RRPPGGTSPPNGGLPGPLATSAAPPGPPAA 54
           P   Q P+QPQ P    P T  QQA A   +RPP    PP+     PL       G P+A
Sbjct: 779 PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSA 838

Query: 55  ASPCLGPVAAAG-SGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111
            S    P+   G  G      G L   P PPQ     P A+   +  G S     P +
Sbjct: 839 PSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHT 896



 Score = 37.0 bits (84), Expect = 0.097
 Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 6/110 (5%)

Query: 6   PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAA 65
           P  Q ++       QQ + +  P     P G  P P   S+APPG P   +P   P A A
Sbjct: 716 PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP---SSAPPGTPQLPTPGPTPSATA 772

Query: 66  --GSGLRRGAEGILAPQ-PPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
               G    ++    PQ P  P  H     A A+   R  S    P  SP
Sbjct: 773 VPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP 822



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 30/111 (27%), Positives = 38/111 (34%), Gaps = 7/111 (6%)

Query: 9   QPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSG 68
           QP   Q P     A +  PPG    P  G P P AT+  P G P A+     P A     
Sbjct: 737 QPPALQAPTGVTPAPSSAPPGTPQLPTPG-PTPSATAVPPQGSPTASQAPNQPQAPTAPV 795

Query: 69  LRRGAEGILA------PQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPV 113
                +   A      P P PP      P    +  + GQ +     Q P+
Sbjct: 796 PHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL 846



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 33/111 (29%), Positives = 42/111 (37%), Gaps = 15/111 (13%)

Query: 2    LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
            L P PL  P   + PP T       P     PP+   P P + +A  P PPA     L P
Sbjct: 918  LPPAPLAMP-HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPA-----LKP 971

Query: 62   VAAAGSGLRRGAEGILAPQPPPPQ---QHQERPGAAAIGSARGQSTGKGPP 109
            +++  +     A       PPP Q   Q Q  P + A      QS    PP
Sbjct: 972  LSSLSTHHPPSA------HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 1016


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 134/508 (26%), Positives = 181/508 (35%), Gaps = 82/508 (16%)

Query: 577  KGKEKEVDGLLTSEPMGSPVSSKTES-VSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSP 635
            K  ++E DGL     M +  S  + S +     K P +P G T    +      S   SP
Sbjct: 3    KPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRS--SGRNSP 60

Query: 636  PVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHST--- 692
                    D      AE VKKS      +  +P K      +  ++ T    RT S    
Sbjct: 61   SAASTSSNDSK----AETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTK 116

Query: 693  ------PSIPVLTAGQS---------GLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSV 737
                  P+ P    G+S         G   P+ I    +    P++ +PQ       +S 
Sbjct: 117  TQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNR-STSPSIPSPQDNESDSDSSA 175

Query: 738  PGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFP- 796
              QQ   +    +L         P+SAPP        GP     TP ++ +P  PQ  P 
Sbjct: 176  --QQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP-----TPSATAVP--PQGSPT 226

Query: 797  GQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYAT 856
               A  QP A  P+ PV    +Q  P +     HPQ   S   P +PS   P      + 
Sbjct: 227  ASQAPNQPQA--PTAPVPHTHIQQAPAL-----HPQRPPSPHPPPHPSPHPPLQPLTGSA 279

Query: 857  VHQSYPHHATQ-LHAHQPQPATTPTGSQPQSQHAAPS-----PVQHQAGQAPHLGSGQ-- 908
               S P HA   LH   P P      + P  QH  P      P Q   GQAP LG+    
Sbjct: 280  GQPSAPSHAQPPLHGQGP-PGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAP-LGTSPAA 337

Query: 909  --PQQNLYHPGALTGT----PPS---LPPGPSAQ--------SPQSSFPQPAAVYAIHHQ 951
              P  +L  P + +      PP    LPP P A         +P    P P A     H 
Sbjct: 338  AYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHL 397

Query: 952  QLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVP 1011
              P  F+  A++        +++    HP + HPP + L+  PQS   P   A P    P
Sbjct: 398  SGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM--PQSQPLPSSPAQP----P 451

Query: 1012 ALSASTPSPYPYIGHPQ------APLPP 1033
             L+ S   P P   HP       AP PP
Sbjct: 452  GLTQSQNLPPPPASHPPTGLHQVAPQPP 479



 Score = 77.8 bits (190), Expect = 5e-14
 Identities = 137/558 (24%), Positives = 189/558 (33%), Gaps = 116/558 (20%)

Query: 543  EELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTES 602
            E++R  G      PS++  +S D     + K   K KE+    L +++     V+S TE 
Sbjct: 50   EDIRSSGRN---SPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEE 106

Query: 603  VSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPN 662
                  K        T+  E   P  PS+         +GE  D   V           N
Sbjct: 107  ADRTSSKK-------TKTQEISRPNSPSEG--------EGESSDSRSV-----------N 140

Query: 663  AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIP-----VLTAGQSGLYSPQYISYIPQI 717
             +  +  K +   N+STS P+ P P+ + + S       +L A    L +P  ++  P  
Sbjct: 141  DEGSSDPKDIDQDNRSTS-PSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSS 199

Query: 718  HMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPP 777
                  Q P   P P + +VP Q        GS    ++     A   P+        P 
Sbjct: 200  APPGTPQLPTPGPTPSATAVPPQ--------GSPTASQAPNQPQAPTAPVPHTHIQQAPA 251

Query: 778  LVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSS 837
            L    P S + P +P   P     +QP+     QP  AP     P        P ++ + 
Sbjct: 252  LHPQRPPSPHPPPHPSPHPP----LQPLTGSAGQPS-APSHAQPPLHGQGPPGPHSLQAG 306

Query: 838  STPQYPSAEQP---TPQA------LYATVHQSYPHHATQLHAHQ---------------P 873
               Q+P   QP    PQA      L  +   +YPH + QL A Q               P
Sbjct: 307  PLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPP 366

Query: 874  QPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQP---QQNLYHPGAL-------TGTP 923
             P   P    P +      P        PHL    P     NL  P AL       T  P
Sbjct: 367  APLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHP 426

Query: 924  PSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFT---NMAHVTQAHVQTGITAAPPPHP 980
            PS  P P    PQS  P P++         P G T   N+     +H  TG+    P  P
Sbjct: 427  PSAHPPPLQLMPQSQ-PLPSS------PAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPP 479

Query: 981  GAPH------PPQV------MLLHPPQSHG----GPPQGAVPQSGVPALSASTPSPYPYI 1024
             A H      PP +          PP   G     P  GA    G  A  +S P P   I
Sbjct: 480  FAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQI 539

Query: 1025 --------GHPQAPLPPP 1034
                      P++P PPP
Sbjct: 540  KEEALDDAEEPESPPPPP 557



 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 133/610 (21%), Positives = 211/610 (34%), Gaps = 109/610 (17%)

Query: 430 SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVS--DP 487
           SG+ S+    + G M   RS +   PA  S      PI   + +S  + P  +S S  D 
Sbjct: 13  SGKHSMRTRRSRGSMSTLRSGRKKQPA--SPDGRTSPINEDIRSSGRNSPSAASTSSNDS 70

Query: 488 GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547
              ++  ++ K+    +   + + ++  +     E A         +   K+ + +E+ +
Sbjct: 71  KAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEAD--------RTSSKKTKTQEISR 122

Query: 548 FGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD--GLLTSEPMGSPVSSKTESVSD 605
                   P+S  E   +    R + +E     K++D     TS  + SP  ++++S S 
Sbjct: 123 --------PNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSS 174

Query: 606 KEDK-----PPL--APSGGTEGPEQPPP---------PCPSQTGSPPVGLIKGEDKDEGP 649
            + +     PP   AP+G T  P   PP         P PS T  PP G          P
Sbjct: 175 AQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQP 234

Query: 650 VAEQV--------KKSTLNPNAKEF-------NPTKPLLSVNKSTSTPTSPGPRTHSTPS 694
            A           +   L+P            +P  PL  +  S   P++P   +H+ P 
Sbjct: 235 QAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP---SHAQP- 290

Query: 695 IPVLTAGQSGLYS------------PQYISYIPQIHMGPA---VQAPQMYPYPVSNSVPG 739
            P+   G  G +S            PQ     PQ   G A         YP+  S  +P 
Sbjct: 291 -PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH-TSLQLPA 348

Query: 740 QQGKYRGAKG-------------------------SLPPQRSDQHQPASAPPMMQAAAAA 774
            Q   +  +                           LP  ++ +H P  + P   +  A 
Sbjct: 349 SQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNAN 408

Query: 775 GPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAH-YPSQPVFAPML-QSNPRMLTSGSHPQ 832
            PP  A  P SS   ++P      P  + P +   PS P   P L QS        SHP 
Sbjct: 409 LPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPP 468

Query: 833 AIVSSSTPQYPSAEQP-TPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAP 891
             +    PQ P A+ P  P         + P  +T        PA   T +QP    AA 
Sbjct: 469 TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP-------PAGPGTSAQPPCSGAAA 521

Query: 892 SPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQ 951
           S      G +  L + Q ++          +PP  P  PS +      P  A+  A  ++
Sbjct: 522 SGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYK 581

Query: 952 QLPHGFTNMA 961
            L  G+ + A
Sbjct: 582 HLDRGYNSCA 591



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 135/639 (21%), Positives = 209/639 (32%), Gaps = 114/639 (17%)

Query: 374 PGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSP--SNRPSG 431
           P L  L     HH  ++ P P          PS  SP     L  ++ L  P  S+ P+G
Sbjct: 413 PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPS--SPAQPPGLTQSQNLPPPPASHPPTG 470

Query: 432 ETSVPP-PPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPG-- 488
              V P PP     + P  P    P P   S   PP G   P +SA  P + + +  G  
Sbjct: 471 LHQVAPQPPFAQHPFVPGGPPPITP-PTCPSTSTPPAG---PGTSAQPPCSGAAASGGSI 526

Query: 489 VGSISPASPKISLAPTDVKELSTKE----PGRTLEPQ-----------ELARIAGKVPGL 533
            G  S   P + +    + +    E    P R+  P+           + AR    +   
Sbjct: 527 AGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRG 586

Query: 534 QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593
            N   R  L  +   G++   +   + E +      +  +E  + KEKE +     E   
Sbjct: 587 YNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERERER 646

Query: 594 SPVSSKTESVSDKEDK--PPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVA 651
               +   S S  E +   P     G   P   PPP       P +G             
Sbjct: 647 EAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIG------------- 693

Query: 652 EQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP--TSPGPRTHS-----TPSIPVLTAGQSG 704
                           P  P L      + P   SP  R H       P+ P+L     G
Sbjct: 694 ----------------PDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPG 737

Query: 705 LYSPQYISYIPQIHMGPAVQAPQMYPYPV-SNSVPGQQGKYRGAKG-SLPPQRSDQHQPA 762
           LY+           + P ++  ++    +    +  ++ + R   G  + P   D   PA
Sbjct: 738 LYN-----------VDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPA 786

Query: 763 SAPP--MMQAAAAAGPPLVAATPYSSYIP-YNP---QQFPGQPAMMQPMAHYPSQPVFAP 816
           + P     + +A   PP     P++S+ P  NP   ++       ++P   YP +     
Sbjct: 787 ANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAER 846

Query: 817 MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQP- 875
           +       LTS    +  + + TP                 H  + H  + LH HQ  P 
Sbjct: 847 IHAERMASLTSDPLARLQMFNVTPH----------------HHQHSHIHSHLHLHQQDPL 890

Query: 876 ---ATTPTGSQPQSQHAAP--SPVQHQAGQAPHLGSGQP---QQNLYHPGALTGTPPSL- 926
              +  P         A P  +   +  G  P+   GQP    + L HP   T  P  L 
Sbjct: 891 HQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLP 950

Query: 927 ----PPGPSAQSPQSSFPQPAAVYAI-HHQQLPHGFTNM 960
               PP  +A   Q+   Q A +  +   QQ  HG  +M
Sbjct: 951 GAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHGHPHM 989



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 39/134 (29%), Positives = 51/134 (38%), Gaps = 32/134 (23%)

Query: 2   LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNG-----------------GLPGPL-- 42
           L PQ    PS P QPP   Q+    PP  + PP G                 G P P+  
Sbjct: 436 LMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITP 495

Query: 43  ----ATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGS 98
               +TS  P GP  +A P     AA+G  +  G+       P P  Q +E     A+  
Sbjct: 496 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSS-----CPLPTVQIKEE----ALDD 546

Query: 99  ARGQSTGKGPPQSP 112
           A    +   PP+SP
Sbjct: 547 AEEPESPPPPPRSP 560



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 92/374 (24%), Positives = 125/374 (33%), Gaps = 82/374 (21%)

Query: 371 GGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS 430
           G  P  SS PP  P      +PGP   A  +             P +G+ T S   N+P 
Sbjct: 192 GVTPAPSSAPPGTPQL---PTPGPTPSATAV-------------PPQGSPTASQAPNQPQ 235

Query: 431 GETSVPPPPAVGR---MYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDP 487
             T+  P   + +   ++P R P   +P P     P PP+     T SA  P   S + P
Sbjct: 236 APTAPVPHTHIQQAPALHPQRPP---SPHPPPHPSPHPPLQPL--TGSAGQPSAPSHAQP 290

Query: 488 GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547
            +    P  P    A   ++     +P   L PQ      G+ P   +    +    L+ 
Sbjct: 291 PLHGQGPPGPHSLQAGPLLQHPGPPQP-FGLPPQ---ASQGQAPLGTSPAAAYPHTSLQL 346

Query: 548 FGAQFKLQPSSSP-ENSLDPFP-------------------PRILKEEPK---GKEKEVD 584
             +Q  LQ    P E  L P P                   P+  K  P         ++
Sbjct: 347 PASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 406

Query: 585 GLLTSEPMGSPVSSKTESVSDKEDKPPL--------------APSGGTEGPEQPPPPCPS 630
             L   P   P+SS +         PPL               P G T+    PPPP   
Sbjct: 407 ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP--- 463

Query: 631 QTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTH 690
               PP GL   +   + P A+        P      PT P      STSTP + GP T 
Sbjct: 464 -ASHPPTGL--HQVAPQPPFAQHPFVPGGPPPITP--PTCP------STSTPPA-GPGTS 511

Query: 691 STPSIPVLTAGQSG 704
           + P  P   A  SG
Sbjct: 512 AQP--PCSGAAASG 523



 Score = 38.9 bits (89), Expect = 0.026
 Identities = 38/118 (32%), Positives = 46/118 (38%), Gaps = 10/118 (8%)

Query: 4   PQPLQQPSQPQQP----PPT--QQAVA---RRPPGGTSPPNGGLPGPLATSAAPPGPPAA 54
           P   Q P+QPQ P    P T  QQA A   +RPP    PP+     PL       G P+A
Sbjct: 225 PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSA 284

Query: 55  ASPCLGPVAAAG-SGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111
            S    P+   G  G      G L   P PPQ     P A+   +  G S     P +
Sbjct: 285 PSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHT 342



 Score = 37.0 bits (84), Expect = 0.097
 Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 6/110 (5%)

Query: 6   PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAA 65
           P  Q ++       QQ + +  P     P G  P P   S+APPG P   +P   P A A
Sbjct: 162 PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP---SSAPPGTPQLPTPGPTPSATA 218

Query: 66  --GSGLRRGAEGILAPQ-PPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
               G    ++    PQ P  P  H     A A+   R  S    P  SP
Sbjct: 219 VPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP 268



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 30/111 (27%), Positives = 38/111 (34%), Gaps = 7/111 (6%)

Query: 9   QPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSG 68
           QP   Q P     A +  PPG    P  G P P AT+  P G P A+     P A     
Sbjct: 183 QPPALQAPTGVTPAPSSAPPGTPQLPTPG-PTPSATAVPPQGSPTASQAPNQPQAPTAPV 241

Query: 69  LRRGAEGILA------PQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPV 113
                +   A      P P PP      P    +  + GQ +     Q P+
Sbjct: 242 PHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL 292



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 33/111 (29%), Positives = 42/111 (37%), Gaps = 15/111 (13%)

Query: 2   LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
           L P PL  P   + PP T       P     PP+   P P + +A  P PPA     L P
Sbjct: 364 LPPAPLAMP-HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPA-----LKP 417

Query: 62  VAAAGSGLRRGAEGILAPQPPPPQ---QHQERPGAAAIGSARGQSTGKGPP 109
           +++  +     A       PPP Q   Q Q  P + A      QS    PP
Sbjct: 418 LSSLSTHHPPSA------HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 462


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 79.7 bits (195), Expect = 1e-14
 Identities = 141/592 (23%), Positives = 201/592 (33%), Gaps = 102/592 (17%)

Query: 490  GSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEEL---R 546
            G  SP    +S + +D K   +++  +    +E +       G   E    + EE    +
Sbjct: 31   GRASPGG--VSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPK 88

Query: 547  KFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD--GLLTSEPMGSPVSSKTESVS 604
            K   + +L    SP + LD    R L ++     +++D     TS  + SP S + +S S
Sbjct: 89   KTKTEQELPRPQSPSD-LDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDS 147

Query: 605  DKEDKPPLAPSGGTEGPEQP--PPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPN 662
                      SG ++GP +P  PPP    +  PP      +     P A      ++ P 
Sbjct: 148  S---------SGLSQGPARPYHPPPLFPPSPQPP------DSTPRQPEASFEPHPSVTPT 192

Query: 663  AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722
                    P   + ++      P P+ +   +  VL+    G       S +   + G  
Sbjct: 193  GYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQ 252

Query: 723  VQAPQMYPYPVSNSVPGQQGKYR----------GAKGSLPPQRSDQHQPASAPPMMQAA- 771
               P     P+S S  G  G             G   S PP  +  H   + PP      
Sbjct: 253  HPPPTT---PISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRP 309

Query: 772  ---AAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRML--- 825
               A+A PP + A P        P   P   AM Q M   P  P   P L  +P  L   
Sbjct: 310  LNNASASPPGLGAQPL-------PGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPA 362

Query: 826  -------------TSGSHPQAIVSSSTPQYPSAEQPTP--QALYATVHQSYPHHATQLHA 870
                         +S S   A  SSS+    S+  P P  QAL      SYPH       
Sbjct: 363  SSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQAL-----PSYPHSF----- 412

Query: 871  HQPQPATTPTGSQPQ--SQHAAPSPVQHQAGQAPHLGSGQPQQNLY-HPGALTGTPPSLP 927
              P P +    +QP   +Q + PS      G  P    G+   N   HPG          
Sbjct: 413  --PPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPG---------- 460

Query: 928  PGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQ 987
            P P +   QS+   P + +  HHQQ            Q   Q    + PPP    PHP  
Sbjct: 461  PFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHP-- 518

Query: 988  VMLLHPPQSHGGPPQGAVPQSG----VPALSASTPSPYPYIGHPQA-PLPPP 1034
               L    SH   P    P  G     P   A  P P+  + + QA P  PP
Sbjct: 519  ---LEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPP 567



 Score = 77.0 bits (188), Expect = 8e-14
 Identities = 175/730 (23%), Positives = 239/730 (32%), Gaps = 124/730 (16%)

Query: 391  SPGPGSEARGIN----GGPSRMSP--KAQRPLRGAKTL-----SSPSNRPSGETSVPPPP 439
            +PGP  E R       GG S  S   KA++  + AK       S+P     G +      
Sbjct: 20   APGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISES 79

Query: 440  AVGRMYPPRSPKSAA--PAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPA-- 495
                   P+  K+    P P S S  +   G ++    +S P      D    S SP+  
Sbjct: 80   ESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDI---DQDNRSTSPSIY 136

Query: 496  SPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQ 555
            SP      +D     ++ P R   P  L   + + P     Q     E            
Sbjct: 137  SPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHA 196

Query: 556  PSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSD----KEDKPP 611
            P   P + +   PP      P+       G+L+  PMG        SV      K+  PP
Sbjct: 197  PMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPP 256

Query: 612  LAP-SGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTK 670
              P S  + G    PP  P  T   PVG   G +    P        T N       P  
Sbjct: 257  TTPISVSSSGASGAPPTKPPTT---PVG---GGNLPSAPPPANFPHVTPN-----LPPPP 305

Query: 671  PLLSVNKSTSTPTSPG--PRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQ-APQ 727
             L  +N ++++P   G  P     PS   +  G  GL         P    GP +  +P 
Sbjct: 306  ALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLP--------PGPEKGPTLAPSPH 357

Query: 728  MYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSY 787
              P P S+S P             PP R      +S+     +++++     +  P S  
Sbjct: 358  SLP-PASSSAPA------------PPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQA 404

Query: 788  IPYNPQQFPGQPAM----MQPMAHYPSQPVFAPMLQSNP------RMLT-SGSHPQAIVS 836
            +P  P  FP   ++      P    PS P  A   Q  P      R+L  S +HP     
Sbjct: 405  LPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPP 464

Query: 837  SSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQ- 895
            S+  Q  S   P P + +   HQ       Q    Q Q       S P    A P P++ 
Sbjct: 465  STGAQ--STAHP-PVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEG 521

Query: 896  ------HQAGQAPHLGSGQP------------QQNLYHPGALTGTPPSLPPGPSAQSPQS 937
                  H    +P LGS +P             Q  Y      G P S     S+ + Q 
Sbjct: 522  GSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQG 581

Query: 938  SFPQPAAVYAIHHQQLPHGFTNMAHVT--QAHVQTGI-----------TAAPP------- 977
            S+P      +   Q  P+ F  +  VT   A + T I           TA+PP       
Sbjct: 582  SYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGK 641

Query: 978  --PHPGA---PHPPQVMLLHPPQSHGGPPQG-------AVPQSGVPALSASTPSPYPYIG 1025
              P PGA     PP      PP    G P G       A P +  P      P P P  G
Sbjct: 642  RAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAG 701

Query: 1026 HPQAP-LPPP 1034
                P LPPP
Sbjct: 702  PSGLPSLPPP 711



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 146/633 (23%), Positives = 197/633 (31%), Gaps = 114/633 (18%)

Query: 371 GGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS 430
           GG  G+ S PP GP        G  S   G NGG     P     +  +    +P  +P 
Sbjct: 222 GGTGGVLSGPPMGP-----KGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKP- 275

Query: 431 GETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVG 490
                 P   VG    P +P  A    ++ + P PP    +  +SAS P   +   PG  
Sbjct: 276 ------PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPG-- 327

Query: 491 SISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGA 550
              P+   +      +     K P     P  L   +   P       RF         A
Sbjct: 328 -HLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPA---PPMRFPYSSSSSSSA 383

Query: 551 QFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKP 610
                 SSS  +S  PFP                  L S P   P              P
Sbjct: 384 AAS-SSSSSSSSSASPFP--------------ASQALPSYPHSFP--------------P 414

Query: 611 PLAPSGGTEGPEQPPPPCPSQT----GSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEF 666
           P + S   + P+   P  PSQ     G PP            P    +  S  +P     
Sbjct: 415 PTSLSVSNQPPKYTQPSLPSQAVWSQGPPP----------PPPYGRLLANSNAHP----- 459

Query: 667 NPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAP 726
            P  P      +   P S     H           Q      Q      Q H       P
Sbjct: 460 GPFPPSTGAQSTAHPPVSTHHHHHQQQQ-------QQQQQQQQQQQQQQQHHGNSGPPPP 512

Query: 727 QMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPP-----MMQAAAAAGPPLVAA 781
             +P+P+          Y     SL   R     PA  PP         A   GPP+ ++
Sbjct: 513 GAFPHPLEGGSSHHAHPY-AMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSS 571

Query: 782 TPYSSYIPYN--PQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSST 839
           +  SS       P   P  P+     A YP  PV  P + ++   L   S   A V+SS 
Sbjct: 572 SNSSSSTSQGSYPCSHP-SPSQGPQGAPYPFPPV--PTVTTSSATL---STVIATVASSP 625

Query: 840 PQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAG 899
             Y +A  P P           P +  +  +       TP G +P       SP   + G
Sbjct: 626 AGYKTASPPGP-----------PPYGKRAPSPGAYKTATPPGYKP------GSPPSFRTG 668

Query: 900 QAP-HLGSGQPQ-QNLYHPGALTGTPPSLPP-GPSAQSPQSSFPQPAAVYAIHHQQLPHG 956
             P + G+  P     + PG+ T  P  LPP GPS      S P P A  A      P  
Sbjct: 669 TPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSG---LPSLPPPPAAPA---SGPPLS 722

Query: 957 FTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVM 989
            T +        +T  +  PP    +P PP+V+
Sbjct: 723 ATQIKQEPAEEYETPESPVPPARSPSP-PPKVV 754



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 131/564 (23%), Positives = 178/564 (31%), Gaps = 123/564 (21%)

Query: 359 GPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNS----SPGPGSEARGINGG---------- 404
           GP+GG   SS  G   G    PP  P  + +S    +P        + GG          
Sbjct: 234 GPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPAN 293

Query: 405 -----PSRMSPKAQRPLRGAKT-------------LSSPSNRPSGETSVPPPPAVGRMYP 446
                P+   P A RPL  A               L SP     G   +PP P  G    
Sbjct: 294 FPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLA 353

Query: 447 PRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDV 506
           P SP S  PA  S+S P PP+           P +SS S     S S +S   S +P   
Sbjct: 354 P-SPHSLPPA--SSSAPAPPM---------RFPYSSSSSSSAAASSSSSSSSSSASPFPA 401

Query: 507 KELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSL-- 564
            +     P     P  L+        + N+  ++    L       +  P   P   L  
Sbjct: 402 SQALPSYPHSFPPPTSLS--------VSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLA 453

Query: 565 ------DPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSS-----KTESVSDKEDKPPLA 613
                  PFPP                  T+ P   PVS+     + +    ++ +    
Sbjct: 454 NSNAHPGPFPP------------STGAQSTAHP---PVSTHHHHHQQQQQQQQQQQQQQQ 498

Query: 614 PSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLL 673
                 G   PPPP     G+ P  L  G      P A      +L P      P  P  
Sbjct: 499 QQQQHHGNSGPPPP-----GAFPHPLEGGSSHHAHPYAMSPSLGSLRP-----YPPGP-- 546

Query: 674 SVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP- 732
                   P S    + + P+ P +++  +   S    SY P  H  P+ Q PQ  PYP 
Sbjct: 547 ---AHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSY-PCSHPSPS-QGPQGAPYPF 601

Query: 733 ------------VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAG----- 775
                       +S  +        G K + PP      + A +P   + A   G     
Sbjct: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS 661

Query: 776 -PPLVAATP---YSSYIPYNPQQF-PGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSH 830
            P     TP     +  P  P  F PG P  + P    P+ P   P L   P    SG  
Sbjct: 662 PPSFRTGTPPGYRGTSPPAGPGTFKPGSPT-VGPGPLPPAGPSGLPSLPPPPAAPASGPP 720

Query: 831 PQAIVSSSTP--QYPSAEQPTPQA 852
             A      P  +Y + E P P A
Sbjct: 721 LSATQIKQEPAEEYETPESPVPPA 744



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 133/590 (22%), Positives = 201/590 (34%), Gaps = 102/590 (17%)

Query: 351  PLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSP 410
            P P   R    G  + ++  G +PG        P      +P PG        GP    P
Sbjct: 636  PPPYGKRAPSPGAYKTATPPGYKPG-------SPPSFRTGTP-PGYRGTSPPAGPGTFKP 687

Query: 411  KAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKS------------AAPAPI 458
             +  P  G   L  P   PSG  S+PPPPA     PP S                +P P 
Sbjct: 688  GS--PTVGPGPL--PPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPP 743

Query: 459  SASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRT- 517
            + S   PP    VP+ ++     +   D G  S   A   +   P +  +L+ K      
Sbjct: 744  ARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSC--ARSDLYFVPLEGSKLAKKRADLVE 801

Query: 518  ---LEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKL-QPSSSPEN--SLDPFPPRI 571
                E ++ AR   +    +  +K  + E+ R+     KL Q   +P    SL P P R 
Sbjct: 802  KVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRP 861

Query: 572  LKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPC--P 629
              E           + T  P   P +    ++S+   +P +   G    P   P     P
Sbjct: 862  PFEPG-------SAVATVPPYLGPDTPALRTLSEYA-RPHVMSPGNRNHPFYVPLGAVDP 913

Query: 630  SQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTS--PGP 687
               G     L   +     P A + ++     + ++    KP   V  S   P    PGP
Sbjct: 914  GLLGYNVPALYSSD-----PAAREREREARERDLRD--RLKPGFEVKPSELEPLHGVPGP 966

Query: 688  RTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQ--APQMYPYPVSNSV-PGQQGKY 744
                 P                        H G A+Q   P ++P+P   S+ P ++ + 
Sbjct: 967  GLDPFPR-----------------------HGGLALQPGPPGLHPFPFHPSLGPLERERL 1003

Query: 745  RGAKG-SLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQ--QFPGQPAM 801
              A G +L P  S   + A+     +  AA G   +A     +  P++ Q         +
Sbjct: 1004 ALAAGPALRPDMSYAERLAAERQHAERVAALGNDPLARLQMLNVTPHHHQHSHIHSHLHL 1063

Query: 802  MQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSY 861
             Q  A + +     P++      L SGSH   I       YP+   P P          +
Sbjct: 1064 HQQDAIHAASASVHPLIDP----LASGSHLTRI------PYPAGTLPNPLL-------PH 1106

Query: 862  PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQ 911
            P H  ++  HQ   A  P    P S  +AP    HQ  QA H  S + Q+
Sbjct: 1107 PLHENEVLRHQLFAA--PYRDLPASL-SAPMSAAHQL-QAMHAQSAELQR 1152



 Score = 40.4 bits (93), Expect = 0.009
 Identities = 68/298 (22%), Positives = 92/298 (30%), Gaps = 41/298 (13%)

Query: 385 HHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRM 444
           HH ++  P PG+    + GG S  +     P   + +L S    P G   +PPP      
Sbjct: 503 HHGNSGPPPPGAFPHPLEGGSSHHA----HPYAMSPSLGSLRPYPPGPAHLPPP------ 552

Query: 445 YPPRSPKSAAP--APISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLA 502
           +   S   A P   P+S+S       S+  TS  S P +      G        P +   
Sbjct: 553 HSQVSYSQAGPNGPPVSSSS-----NSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTV 607

Query: 503 PTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN 562
            T    LST     T+            PG     KR       K       +P S    
Sbjct: 608 TTSSATLSTVIA--TVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS---- 661

Query: 563 SLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPE 622
                PP      P G         TS P G                PP  PSG    P 
Sbjct: 662 -----PPSFRTGTPPGYRG------TSPPAGPGTFKPGSPTVGPGPLPPAGPSGL---PS 707

Query: 623 QPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTS 680
            PPPP    +G P    +      + P  E     +  P A+  +P   ++ V    S
Sbjct: 708 LPPPPAAPASGPP----LSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHAS 761



 Score = 37.0 bits (84), Expect = 0.097
 Identities = 31/95 (32%), Positives = 37/95 (38%), Gaps = 18/95 (18%)

Query: 12  QPQQPPPTQQAVARRPPG--GTSPPNGGL----------PGPL---ATSAAPPGPPAAAS 56
           +P  PP  +      PPG  GTSPP G            PGPL     S  P  PP  A+
Sbjct: 658 KPGSPPSFRTGT---PPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAA 714

Query: 57  PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERP 91
           P  GP  +A    +  AE    P+ P P      P
Sbjct: 715 PASGPPLSATQIKQEPAEEYETPESPVPPARSPSP 749



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 22/52 (42%), Positives = 25/52 (48%), Gaps = 6/52 (11%)

Query: 4   PQPLQQ--PSQPQQ-PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPP 52
           P P  Q  PS P   PPPT  +V+ +PP  T P    LP     S  PP PP
Sbjct: 398 PFPASQALPSYPHSFPPPTSLSVSNQPPKYTQP---SLPSQAVWSQGPPPPP 446



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 32/104 (30%), Positives = 37/104 (35%), Gaps = 19/104 (18%)

Query: 8   QQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGS 67
           QQ  Q QQ    QQ   +       PP G  P PL   ++    P A SP LG       
Sbjct: 485 QQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGS------ 538

Query: 68  GLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111
                    L P PP P  H   P +    S  G +   GPP S
Sbjct: 539 ---------LRPYPPGP-AHLPPPHSQVSYSQAGPN---GPPVS 569



 Score = 33.9 bits (76), Expect = 0.82
 Identities = 34/113 (30%), Positives = 42/113 (37%), Gaps = 16/113 (14%)

Query: 4   PQPLQQPS-QPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPV 62
           P PL  PS QP    P Q   +  P    +P     P    TS     PP A  P   P 
Sbjct: 161 PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPP--HPQ 218

Query: 63  AAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK--GPPQSPV 113
              G     G  G+L+  P  P+      G  A  S  G + GK   PP +P+
Sbjct: 219 LYPG-----GTGGVLSGPPMGPK------GGGAASSVGGPNGGKQHPPPTTPI 260



 Score = 33.1 bits (74), Expect = 1.4
 Identities = 28/96 (29%), Positives = 31/96 (32%), Gaps = 3/96 (3%)

Query: 14  QQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGA 73
           Q PPPT            +PP      P+     P  PP A  P + P       LR   
Sbjct: 252 QHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLN 311

Query: 74  EGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109
               A   PP    Q  PG      A GQ  G  PP
Sbjct: 312 N---ASASPPGLGAQPLPGHLPSPHAMGQGMGGLPP 344


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 79.7 bits (195), Expect = 1e-14
 Identities = 141/592 (23%), Positives = 201/592 (33%), Gaps = 102/592 (17%)

Query: 490  GSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEEL---R 546
            G  SP    +S + +D K   +++  +    +E +       G   E    + EE    +
Sbjct: 31   GRASPGG--VSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPK 88

Query: 547  KFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD--GLLTSEPMGSPVSSKTESVS 604
            K   + +L    SP + LD    R L ++     +++D     TS  + SP S + +S S
Sbjct: 89   KTKTEQELPRPQSPSD-LDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDS 147

Query: 605  DKEDKPPLAPSGGTEGPEQP--PPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPN 662
                      SG ++GP +P  PPP    +  PP      +     P A      ++ P 
Sbjct: 148  S---------SGLSQGPARPYHPPPLFPPSPQPP------DSTPRQPEASFEPHPSVTPT 192

Query: 663  AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722
                    P   + ++      P P+ +   +  VL+    G       S +   + G  
Sbjct: 193  GYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQ 252

Query: 723  VQAPQMYPYPVSNSVPGQQGKYR----------GAKGSLPPQRSDQHQPASAPPMMQAA- 771
               P     P+S S  G  G             G   S PP  +  H   + PP      
Sbjct: 253  HPPPTT---PISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRP 309

Query: 772  ---AAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRML--- 825
               A+A PP + A P        P   P   AM Q M   P  P   P L  +P  L   
Sbjct: 310  LNNASASPPGLGAQPL-------PGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPA 362

Query: 826  -------------TSGSHPQAIVSSSTPQYPSAEQPTP--QALYATVHQSYPHHATQLHA 870
                         +S S   A  SSS+    S+  P P  QAL      SYPH       
Sbjct: 363  SSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQAL-----PSYPHSF----- 412

Query: 871  HQPQPATTPTGSQPQ--SQHAAPSPVQHQAGQAPHLGSGQPQQNLY-HPGALTGTPPSLP 927
              P P +    +QP   +Q + PS      G  P    G+   N   HPG          
Sbjct: 413  --PPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPG---------- 460

Query: 928  PGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQ 987
            P P +   QS+   P + +  HHQQ            Q   Q    + PPP    PHP  
Sbjct: 461  PFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHP-- 518

Query: 988  VMLLHPPQSHGGPPQGAVPQSG----VPALSASTPSPYPYIGHPQA-PLPPP 1034
               L    SH   P    P  G     P   A  P P+  + + QA P  PP
Sbjct: 519  ---LEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPP 567



 Score = 77.0 bits (188), Expect = 8e-14
 Identities = 175/730 (23%), Positives = 239/730 (32%), Gaps = 124/730 (16%)

Query: 391  SPGPGSEARGIN----GGPSRMSP--KAQRPLRGAKTL-----SSPSNRPSGETSVPPPP 439
            +PGP  E R       GG S  S   KA++  + AK       S+P     G +      
Sbjct: 20   APGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISES 79

Query: 440  AVGRMYPPRSPKSAA--PAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPA-- 495
                   P+  K+    P P S S  +   G ++    +S P      D    S SP+  
Sbjct: 80   ESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDI---DQDNRSTSPSIY 136

Query: 496  SPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQ 555
            SP      +D     ++ P R   P  L   + + P     Q     E            
Sbjct: 137  SPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHA 196

Query: 556  PSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSD----KEDKPP 611
            P   P + +   PP      P+       G+L+  PMG        SV      K+  PP
Sbjct: 197  PMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPP 256

Query: 612  LAP-SGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTK 670
              P S  + G    PP  P  T   PVG   G +    P        T N       P  
Sbjct: 257  TTPISVSSSGASGAPPTKPPTT---PVG---GGNLPSAPPPANFPHVTPN-----LPPPP 305

Query: 671  PLLSVNKSTSTPTSPG--PRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQ-APQ 727
             L  +N ++++P   G  P     PS   +  G  GL         P    GP +  +P 
Sbjct: 306  ALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLP--------PGPEKGPTLAPSPH 357

Query: 728  MYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSY 787
              P P S+S P             PP R      +S+     +++++     +  P S  
Sbjct: 358  SLP-PASSSAPA------------PPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQA 404

Query: 788  IPYNPQQFPGQPAM----MQPMAHYPSQPVFAPMLQSNP------RMLT-SGSHPQAIVS 836
            +P  P  FP   ++      P    PS P  A   Q  P      R+L  S +HP     
Sbjct: 405  LPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPP 464

Query: 837  SSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQ- 895
            S+  Q  S   P P + +   HQ       Q    Q Q       S P    A P P++ 
Sbjct: 465  STGAQ--STAHP-PVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEG 521

Query: 896  ------HQAGQAPHLGSGQP------------QQNLYHPGALTGTPPSLPPGPSAQSPQS 937
                  H    +P LGS +P             Q  Y      G P S     S+ + Q 
Sbjct: 522  GSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQG 581

Query: 938  SFPQPAAVYAIHHQQLPHGFTNMAHVT--QAHVQTGI-----------TAAPP------- 977
            S+P      +   Q  P+ F  +  VT   A + T I           TA+PP       
Sbjct: 582  SYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGK 641

Query: 978  --PHPGA---PHPPQVMLLHPPQSHGGPPQG-------AVPQSGVPALSASTPSPYPYIG 1025
              P PGA     PP      PP    G P G       A P +  P      P P P  G
Sbjct: 642  RAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAG 701

Query: 1026 HPQAP-LPPP 1034
                P LPPP
Sbjct: 702  PSGLPSLPPP 711



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 146/633 (23%), Positives = 197/633 (31%), Gaps = 114/633 (18%)

Query: 371 GGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS 430
           GG  G+ S PP GP        G  S   G NGG     P     +  +    +P  +P 
Sbjct: 222 GGTGGVLSGPPMGP-----KGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKP- 275

Query: 431 GETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVG 490
                 P   VG    P +P  A    ++ + P PP    +  +SAS P   +   PG  
Sbjct: 276 ------PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPG-- 327

Query: 491 SISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGA 550
              P+   +      +     K P     P  L   +   P       RF         A
Sbjct: 328 -HLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPA---PPMRFPYSSSSSSSA 383

Query: 551 QFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKP 610
                 SSS  +S  PFP                  L S P   P              P
Sbjct: 384 AAS-SSSSSSSSSASPFP--------------ASQALPSYPHSFP--------------P 414

Query: 611 PLAPSGGTEGPEQPPPPCPSQT----GSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEF 666
           P + S   + P+   P  PSQ     G PP            P    +  S  +P     
Sbjct: 415 PTSLSVSNQPPKYTQPSLPSQAVWSQGPPP----------PPPYGRLLANSNAHP----- 459

Query: 667 NPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAP 726
            P  P      +   P S     H           Q      Q      Q H       P
Sbjct: 460 GPFPPSTGAQSTAHPPVSTHHHHHQQQQ-------QQQQQQQQQQQQQQQHHGNSGPPPP 512

Query: 727 QMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPP-----MMQAAAAAGPPLVAA 781
             +P+P+          Y     SL   R     PA  PP         A   GPP+ ++
Sbjct: 513 GAFPHPLEGGSSHHAHPY-AMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSS 571

Query: 782 TPYSSYIPYN--PQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSST 839
           +  SS       P   P  P+     A YP  PV  P + ++   L   S   A V+SS 
Sbjct: 572 SNSSSSTSQGSYPCSHP-SPSQGPQGAPYPFPPV--PTVTTSSATL---STVIATVASSP 625

Query: 840 PQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAG 899
             Y +A  P P           P +  +  +       TP G +P       SP   + G
Sbjct: 626 AGYKTASPPGP-----------PPYGKRAPSPGAYKTATPPGYKP------GSPPSFRTG 668

Query: 900 QAP-HLGSGQPQ-QNLYHPGALTGTPPSLPP-GPSAQSPQSSFPQPAAVYAIHHQQLPHG 956
             P + G+  P     + PG+ T  P  LPP GPS      S P P A  A      P  
Sbjct: 669 TPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSG---LPSLPPPPAAPA---SGPPLS 722

Query: 957 FTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVM 989
            T +        +T  +  PP    +P PP+V+
Sbjct: 723 ATQIKQEPAEEYETPESPVPPARSPSP-PPKVV 754



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 131/564 (23%), Positives = 178/564 (31%), Gaps = 123/564 (21%)

Query: 359 GPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNS----SPGPGSEARGINGG---------- 404
           GP+GG   SS  G   G    PP  P  + +S    +P        + GG          
Sbjct: 234 GPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPAN 293

Query: 405 -----PSRMSPKAQRPLRGAKT-------------LSSPSNRPSGETSVPPPPAVGRMYP 446
                P+   P A RPL  A               L SP     G   +PP P  G    
Sbjct: 294 FPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLA 353

Query: 447 PRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDV 506
           P SP S  PA  S+S P PP+           P +SS S     S S +S   S +P   
Sbjct: 354 P-SPHSLPPA--SSSAPAPPM---------RFPYSSSSSSSAAASSSSSSSSSSASPFPA 401

Query: 507 KELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSL-- 564
            +     P     P  L+        + N+  ++    L       +  P   P   L  
Sbjct: 402 SQALPSYPHSFPPPTSLS--------VSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLA 453

Query: 565 ------DPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSS-----KTESVSDKEDKPPLA 613
                  PFPP                  T+ P   PVS+     + +    ++ +    
Sbjct: 454 NSNAHPGPFPP------------STGAQSTAHP---PVSTHHHHHQQQQQQQQQQQQQQQ 498

Query: 614 PSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLL 673
                 G   PPPP     G+ P  L  G      P A      +L P      P  P  
Sbjct: 499 QQQQHHGNSGPPPP-----GAFPHPLEGGSSHHAHPYAMSPSLGSLRP-----YPPGP-- 546

Query: 674 SVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP- 732
                   P S    + + P+ P +++  +   S    SY P  H  P+ Q PQ  PYP 
Sbjct: 547 ---AHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSY-PCSHPSPS-QGPQGAPYPF 601

Query: 733 ------------VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAG----- 775
                       +S  +        G K + PP      + A +P   + A   G     
Sbjct: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS 661

Query: 776 -PPLVAATP---YSSYIPYNPQQF-PGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSH 830
            P     TP     +  P  P  F PG P  + P    P+ P   P L   P    SG  
Sbjct: 662 PPSFRTGTPPGYRGTSPPAGPGTFKPGSPT-VGPGPLPPAGPSGLPSLPPPPAAPASGPP 720

Query: 831 PQAIVSSSTP--QYPSAEQPTPQA 852
             A      P  +Y + E P P A
Sbjct: 721 LSATQIKQEPAEEYETPESPVPPA 744



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 133/590 (22%), Positives = 201/590 (34%), Gaps = 102/590 (17%)

Query: 351  PLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSP 410
            P P   R    G  + ++  G +PG        P      +P PG        GP    P
Sbjct: 636  PPPYGKRAPSPGAYKTATPPGYKPG-------SPPSFRTGTP-PGYRGTSPPAGPGTFKP 687

Query: 411  KAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKS------------AAPAPI 458
             +  P  G   L  P   PSG  S+PPPPA     PP S                +P P 
Sbjct: 688  GS--PTVGPGPL--PPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPP 743

Query: 459  SASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRT- 517
            + S   PP    VP+ ++     +   D G  S   A   +   P +  +L+ K      
Sbjct: 744  ARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSC--ARSDLYFVPLEGSKLAKKRADLVE 801

Query: 518  ---LEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKL-QPSSSPEN--SLDPFPPRI 571
                E ++ AR   +    +  +K  + E+ R+     KL Q   +P    SL P P R 
Sbjct: 802  KVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRP 861

Query: 572  LKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPC--P 629
              E           + T  P   P +    ++S+   +P +   G    P   P     P
Sbjct: 862  PFEPG-------SAVATVPPYLGPDTPALRTLSEYA-RPHVMSPGNRNHPFYVPLGAVDP 913

Query: 630  SQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTS--PGP 687
               G     L   +     P A + ++     + ++    KP   V  S   P    PGP
Sbjct: 914  GLLGYNVPALYSSD-----PAAREREREARERDLRD--RLKPGFEVKPSELEPLHGVPGP 966

Query: 688  RTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQ--APQMYPYPVSNSV-PGQQGKY 744
                 P                        H G A+Q   P ++P+P   S+ P ++ + 
Sbjct: 967  GLDPFPR-----------------------HGGLALQPGPPGLHPFPFHPSLGPLERERL 1003

Query: 745  RGAKG-SLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQ--QFPGQPAM 801
              A G +L P  S   + A+     +  AA G   +A     +  P++ Q         +
Sbjct: 1004 ALAAGPALRPDMSYAERLAAERQHAERVAALGNDPLARLQMLNVTPHHHQHSHIHSHLHL 1063

Query: 802  MQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSY 861
             Q  A + +     P++      L SGSH   I       YP+   P P          +
Sbjct: 1064 HQQDAIHAASASVHPLIDP----LASGSHLTRI------PYPAGTLPNPLL-------PH 1106

Query: 862  PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQ 911
            P H  ++  HQ   A  P    P S  +AP    HQ  QA H  S + Q+
Sbjct: 1107 PLHENEVLRHQLFAA--PYRDLPASL-SAPMSAAHQL-QAMHAQSAELQR 1152



 Score = 40.4 bits (93), Expect = 0.009
 Identities = 68/298 (22%), Positives = 92/298 (30%), Gaps = 41/298 (13%)

Query: 385 HHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRM 444
           HH ++  P PG+    + GG S  +     P   + +L S    P G   +PPP      
Sbjct: 503 HHGNSGPPPPGAFPHPLEGGSSHHA----HPYAMSPSLGSLRPYPPGPAHLPPP------ 552

Query: 445 YPPRSPKSAAP--APISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLA 502
           +   S   A P   P+S+S       S+  TS  S P +      G        P +   
Sbjct: 553 HSQVSYSQAGPNGPPVSSSS-----NSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTV 607

Query: 503 PTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN 562
            T    LST     T+            PG     KR       K       +P S    
Sbjct: 608 TTSSATLSTVIA--TVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS---- 661

Query: 563 SLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPE 622
                PP      P G         TS P G                PP  PSG    P 
Sbjct: 662 -----PPSFRTGTPPGYRG------TSPPAGPGTFKPGSPTVGPGPLPPAGPSGL---PS 707

Query: 623 QPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTS 680
            PPPP    +G P    +      + P  E     +  P A+  +P   ++ V    S
Sbjct: 708 LPPPPAAPASGPP----LSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHAS 761



 Score = 37.0 bits (84), Expect = 0.097
 Identities = 31/95 (32%), Positives = 37/95 (38%), Gaps = 18/95 (18%)

Query: 12  QPQQPPPTQQAVARRPPG--GTSPPNGGL----------PGPL---ATSAAPPGPPAAAS 56
           +P  PP  +      PPG  GTSPP G            PGPL     S  P  PP  A+
Sbjct: 658 KPGSPPSFRTGT---PPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAA 714

Query: 57  PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERP 91
           P  GP  +A    +  AE    P+ P P      P
Sbjct: 715 PASGPPLSATQIKQEPAEEYETPESPVPPARSPSP 749



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 22/52 (42%), Positives = 25/52 (48%), Gaps = 6/52 (11%)

Query: 4   PQPLQQ--PSQPQQ-PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPP 52
           P P  Q  PS P   PPPT  +V+ +PP  T P    LP     S  PP PP
Sbjct: 398 PFPASQALPSYPHSFPPPTSLSVSNQPPKYTQP---SLPSQAVWSQGPPPPP 446



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 32/104 (30%), Positives = 37/104 (35%), Gaps = 19/104 (18%)

Query: 8   QQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGS 67
           QQ  Q QQ    QQ   +       PP G  P PL   ++    P A SP LG       
Sbjct: 485 QQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGS------ 538

Query: 68  GLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111
                    L P PP P  H   P +    S  G +   GPP S
Sbjct: 539 ---------LRPYPPGP-AHLPPPHSQVSYSQAGPN---GPPVS 569



 Score = 33.9 bits (76), Expect = 0.82
 Identities = 34/113 (30%), Positives = 42/113 (37%), Gaps = 16/113 (14%)

Query: 4   PQPLQQPS-QPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPV 62
           P PL  PS QP    P Q   +  P    +P     P    TS     PP A  P   P 
Sbjct: 161 PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPP--HPQ 218

Query: 63  AAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK--GPPQSPV 113
              G     G  G+L+  P  P+      G  A  S  G + GK   PP +P+
Sbjct: 219 LYPG-----GTGGVLSGPPMGPK------GGGAASSVGGPNGGKQHPPPTTPI 260



 Score = 33.1 bits (74), Expect = 1.4
 Identities = 28/96 (29%), Positives = 31/96 (32%), Gaps = 3/96 (3%)

Query: 14  QQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGA 73
           Q PPPT            +PP      P+     P  PP A  P + P       LR   
Sbjct: 252 QHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLN 311

Query: 74  EGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109
               A   PP    Q  PG      A GQ  G  PP
Sbjct: 312 N---ASASPPGLGAQPLPGHLPSPHAMGQGMGGLPP 344


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 113/436 (25%), Positives = 142/436 (32%), Gaps = 58/436 (13%)

Query: 580  EKEVDGLLTSEPMGSPVS--SKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPV 637
            ++E   L+   P G+P    +K +       KP   P  G   P+ PPPP     G PP 
Sbjct: 25   QEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP- 83

Query: 638  GLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPV 697
               +G +K +GP      +       K  +P  P          P  P P+  + P  P 
Sbjct: 84   ---QGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP-------PGKPQGPPPQGGNQPQGPP 133

Query: 698  LTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSD 757
               G+     PQ  +  PQ   GP        P P  ++         G     PPQ  +
Sbjct: 134  PPPGKPQGPPPQGGNK-PQ---GPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGN 189

Query: 758  QHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPM 817
            Q Q    PP        GPP     P     P  P   PG+P    P     SQ   +P 
Sbjct: 190  QPQGPPPPP----GKPQGPP-----PQGGNKPQGPPP-PGKPQGPPPQGDNKSQSARSP- 238

Query: 818  LQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPAT 877
                P+    G  PQ     + PQ P      PQ          P          P P  
Sbjct: 239  -PGKPQ----GPPPQG---GNQPQGPPPPPGKPQG---------PPPQGGNKPQGPPPPG 281

Query: 878  TPTGSQPQS---QHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPP---SLPPGPS 931
             P G  PQ      ++ SP     G  P  G  QPQ     PG   G PP   + P GP 
Sbjct: 282  KPQGPPPQGGSKSRSSRSPPGKPQGPPPQ-GGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 340

Query: 932  AQS-PQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVML 990
                PQ   P P         + P G        + +   G    PPP  G P  PQ   
Sbjct: 341  PPGKPQG--PPPQGGSKSRSARSPPGKPQGPPQQEGNNPQG---PPPPAGGNPQQPQAPP 395

Query: 991  LHPPQSHGGPPQGAVP 1006
               PQ    PPQG  P
Sbjct: 396  AGQPQGPPRPPQGGRP 411



 Score = 73.6 bits (179), Expect = 9e-13
 Identities = 102/393 (25%), Positives = 128/393 (32%), Gaps = 67/393 (17%)

Query: 555 QPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSS-KTESVSDKEDKPPLA 613
           QP   P     P P +     P+G  K        +P G P    K+ S      KP   
Sbjct: 67  QPQGPP-----PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGP 121

Query: 614 PSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLL 673
           P  G   P+ PPPP     G PP    +G +K +GP           P  K   P  P  
Sbjct: 122 PPQGGNQPQGPPPPPGKPQGPPP----QGGNKPQGP----------PPPGKPQGP--PPQ 165

Query: 674 SVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQA---PQMYP 730
             NKS S+ + PG      P          G   PQ     P    GP  Q    PQ  P
Sbjct: 166 GDNKSRSSRSPPGKPQGPPP---------QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 216

Query: 731 YPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPY 790
            P         GK +G     PPQ  ++ Q A +PP        GPP     P     P 
Sbjct: 217 PP---------GKPQGP----PPQGDNKSQSARSPP----GKPQGPP-----PQGGNQPQ 254

Query: 791 NPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTP 850
            P   PG+P    P      Q    P     P+    G  PQ    S + + P  +   P
Sbjct: 255 GPPPPPGKPQGPPPQGGNKPQ---GPPPPGKPQ----GPPPQGGSKSRSSRSPPGKPQGP 307

Query: 851 QALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQ 910
                   Q  P    +     PQ    P G  P  +   P P      ++     G+PQ
Sbjct: 308 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQ 367

Query: 911 QNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPA 943
                P    G  P  PP P+  +PQ     PA
Sbjct: 368 ----GPPQQEGNNPQGPPPPAGGNPQQPQAPPA 396



 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 115/450 (25%), Positives = 141/450 (31%), Gaps = 80/450 (17%)

Query: 598  SKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKS 657
            S+ ES S     P  AP  G   P+ PP P     G PP    +G ++ +GP     K  
Sbjct: 24   SQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPP----QGGNQPQGPPPPPGKPQ 79

Query: 658  TLNPNA--KEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIP 715
               P    K   P  P            S  PR  S P  P     Q G   PQ     P
Sbjct: 80   GPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPR--SPPGKPQGPPPQGG-NQPQGPPPPP 136

Query: 716  QIHMGPAVQA---PQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAA 772
                GP  Q    PQ  P P         GK +G     PPQ  ++ + + +PP      
Sbjct: 137  GKPQGPPPQGGNKPQGPPPP---------GKPQGP----PPQGDNKSRSSRSPP----GK 179

Query: 773  AAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQ 832
              GPP     P     P  P   PG+P    P      Q    P     P+    G  PQ
Sbjct: 180  PQGPP-----PQGGNQPQGPPPPPGKPQGPPPQGGNKPQ---GPPPPGKPQ----GPPPQ 227

Query: 833  AIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPS 892
                S + + P  +   P        Q  P    +     PQ    P G  P  +   P 
Sbjct: 228  GDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP 287

Query: 893  PVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQ 952
            P      ++     G+PQ     P    G  P  PP P  + PQ   PQ           
Sbjct: 288  PQGGSKSRSSRSPPGKPQ----GPPPQGGNQPQGPPPPPGK-PQGPPPQG---------- 332

Query: 953  LPHGFTNMAHVTQAHVQTGITAAPPPHPGA--------PHPPQVMLLHPPQSHGGPPQGA 1004
                     +  Q     G    PPP  G+        P  PQ     PPQ  G  PQG 
Sbjct: 333  --------GNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQ----GPPQQEGNNPQGP 380

Query: 1005 VPQSGVPALSASTPSPYPYIGHPQAPLPPP 1034
             P +G        P      G PQ P  PP
Sbjct: 381  PPPAGGNPQQPQAPP----AGQPQGPPRPP 406



 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 109/435 (25%), Positives = 140/435 (32%), Gaps = 57/435 (13%)

Query: 335 SGRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGP 394
           S  ESPSL +   +  P PQ   + P+G         G P      P+GP        GP
Sbjct: 24  SQEESPSLIAGNPQGAP-PQGGNK-PQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 81

Query: 395 GSEARGINGGPSRMSPKAQRPLRGAKTLS--SPSNRPSGET--------SVPPPPAVGRM 444
             +      GP         P +G K+ S  SP  +P G            PPPP   + 
Sbjct: 82  PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 141

Query: 445 YPPRSP-KSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAP 503
            PP+   K   P P       PP G     SS S P       P  G+     P     P
Sbjct: 142 PPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKP 201

Query: 504 TDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFG--AQFKLQPSSSPE 561
                    +P     P    +  G  P   N+ +  +    +  G   Q   QP   P 
Sbjct: 202 QGPPPQGGNKP---QGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPP- 257

Query: 562 NSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPV--SSKTESVSDKEDKPPLAPSGGTE 619
               P P +     P+G  K        +P G P    SK+ S      KP   P  G  
Sbjct: 258 ----PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGN 313

Query: 620 GPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKST 679
            P+ PPPP     G PP    +G +K +GP                  P KP        
Sbjct: 314 QPQGPPPPPGKPQGPPP----QGGNKPQGPPP----------------PGKP-------Q 346

Query: 680 STPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPG 739
             P   G ++ S  S P    G      PQ     PQ    PA   PQ    P +    G
Sbjct: 347 GPPPQGGSKSRSARSPPGKPQG-----PPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQG 401

Query: 740 QQGKYRGAKGSLPPQ 754
                +G + S PPQ
Sbjct: 402 PPRPPQGGRPSRPPQ 416



 Score = 63.9 bits (154), Expect = 7e-10
 Identities = 102/394 (25%), Positives = 119/394 (30%), Gaps = 51/394 (12%)

Query: 650  VAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQ--SGLYS 707
            VA     S  N N        P L        P   G +    PS P    G    G   
Sbjct: 8    VALLALSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQ 67

Query: 708  PQYISYIPQIHMGPAVQA---PQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASA 764
            PQ     P    GP  Q    PQ  P P         GK +G     PPQ      P S 
Sbjct: 68   PQGPPPPPGKPQGPPPQGGNKPQGPPPP---------GKPQGP----PPQGDKSRSPRSP 114

Query: 765  PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRM 824
            P   Q     GPP     P     P  P   PG+P    P      Q    P     P+ 
Sbjct: 115  PGKPQ-----GPP-----PQGGNQPQGPPPPPGKPQGPPPQGGNKPQ---GPPPPGKPQ- 160

Query: 825  LTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQP 884
               G  PQ    S + + P  +   P        Q  P    +     PQ    P G  P
Sbjct: 161  ---GPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 217

Query: 885  QSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAA 944
              +   P P      Q+     G+PQ     P    G  P  PP P  + PQ   PQ   
Sbjct: 218  PGKPQGPPPQGDNKSQSARSPPGKPQG----PPPQGGNQPQGPPPPPGK-PQGPPPQGGN 272

Query: 945  VYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGA 1004
                  Q  P          Q   ++  + +PP  P  P P        P    G PQG 
Sbjct: 273  ----KPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 328

Query: 1005 VPQSGVPALSASTPSPYPYIGHPQAPLPPPGELK 1038
             PQ G      + P   P  G PQ P PP G  K
Sbjct: 329  PPQGG------NKPQGPPPPGKPQGP-PPQGGSK 355



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 104/431 (24%), Positives = 134/431 (31%), Gaps = 57/431 (13%)

Query: 394 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSA 453
           P   A    G P +   K Q P         P  +   +   PPPP      PP    + 
Sbjct: 29  PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 88

Query: 454 APAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKE 513
              P     P+ P      + S   P       P  G   P  P     P   K      
Sbjct: 89  PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP----PPPPGKPQGPPP 144

Query: 514 PG--RTLEPQELARIAGKVPGLQNEQKRFQLEELRKFG--AQFKLQPSSSPENSLDPFPP 569
            G  +   P    +  G  P   N+ +  +    +  G   Q   QP   P     P P 
Sbjct: 145 QGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPP-----PPPG 199

Query: 570 RILKEEPKGKEKEVDGLLTSEPMGSPV--SSKTESVSDKEDKPPLAPSGGTEGPEQPPPP 627
           +     P+G  K        +P G P    +K++S      KP   P  G   P+ PPPP
Sbjct: 200 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPP 259

Query: 628 CPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGP 687
                G PP    +G +K +GP           P  K   P  P    +KS S+ + PG 
Sbjct: 260 PGKPQGPPP----QGGNKPQGP----------PPPGKPQGP--PPQGGSKSRSSRSPPGK 303

Query: 688 RTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQA---PQMYPYPVSNSVPGQQGKY 744
                P          G   PQ     P    GP  Q    PQ  P P     P  QG  
Sbjct: 304 PQGPPP---------QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGS 354

Query: 745 RGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFP-GQP--AM 801
           +      PP +         PP  +     GPP     P +   P  PQ  P GQP    
Sbjct: 355 KSRSARSPPGK------PQGPPQQEGNNPQGPP-----PPAGGNPQQPQAPPAGQPQGPP 403

Query: 802 MQPMAHYPSQP 812
             P    PS+P
Sbjct: 404 RPPQGGRPSRP 414



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 42/131 (32%), Positives = 49/131 (37%), Gaps = 25/131 (19%)

Query: 3   KPQPLQQPSQPQQPPP---TQQAVARRPPG--------GTSPPNGGLPGPLATSAAPP-- 49
           KPQ    P +PQ PPP    +   AR PPG        G + P G  P P      PP  
Sbjct: 211 KPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 270

Query: 50  -----GPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQE------RPGAAAIGS 98
                GPP    P  GP    GS  R        PQ PPPQ   +       PG      
Sbjct: 271 GNKPQGPPPPGKP-QGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 329

Query: 99  ARGQSTGKGPP 109
            +G +  +GPP
Sbjct: 330 PQGGNKPQGPP 340



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 42/131 (32%), Positives = 50/131 (38%), Gaps = 22/131 (16%)

Query: 3   KPQPLQQPSQPQQPPP---TQQAVARRPPG--------GTSPPNGGLPGPLATSAAPP-- 49
           KPQ    P +PQ PPP   ++   +R PPG        G + P G  P P      PP  
Sbjct: 273 KPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 332

Query: 50  -----GPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQ---HQERPGAAAIGSARG 101
                GPP    P  GP    GS  R        PQ PP Q+    Q  P  A     + 
Sbjct: 333 GNKPQGPPPPGKP-QGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQP 391

Query: 102 QSTGKGPPQSP 112
           Q+   G PQ P
Sbjct: 392 QAPPAGQPQGP 402



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 40/133 (30%), Positives = 51/133 (38%), Gaps = 19/133 (14%)

Query: 3   KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLP-----GP-------LATSAAP 48
           KPQ  P Q  +QPQ PPP        PP G + P G  P     GP         ++ +P
Sbjct: 179 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSP 238

Query: 49  PG-----PPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQS 103
           PG     PP   +   GP    G       +G   PQ PPP    + P       +R   
Sbjct: 239 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSR 298

Query: 104 TGKGPPQSPVFEG 116
           +  G PQ P  +G
Sbjct: 299 SPPGKPQGPPPQG 311



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 40/133 (30%), Positives = 51/133 (38%), Gaps = 19/133 (14%)

Query: 3   KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLP-----GP-------LATSAAP 48
           KPQ  P Q  +QPQ PPP        PP G + P G  P     GP         +S +P
Sbjct: 117 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSP 176

Query: 49  PG-----PPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQS 103
           PG     PP   +   GP    G       +G   PQ PPP    + P       ++   
Sbjct: 177 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSAR 236

Query: 104 TGKGPPQSPVFEG 116
           +  G PQ P  +G
Sbjct: 237 SPPGKPQGPPPQG 249



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 45/131 (34%), Positives = 54/131 (41%), Gaps = 23/131 (17%)

Query: 3   KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLP-----GP-------LATSAAP 48
           KPQ  P Q  +QPQ PPP        PP G + P G  P     GP         +S +P
Sbjct: 241 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP 300

Query: 49  PG-----PPAAASPCLGPVAAAGSGLRRGAEGILAPQ-PPPPQQHQERP--GAAAIGSAR 100
           PG     PP   +   GP    G       +G   PQ PPPP + Q  P  G +   SAR
Sbjct: 301 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSAR 360

Query: 101 G-QSTGKGPPQ 110
                 +GPPQ
Sbjct: 361 SPPGKPQGPPQ 371



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 35/109 (32%), Positives = 42/109 (38%), Gaps = 12/109 (11%)

Query: 3   KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
           KPQ  P Q  +QPQ PPP        PP G + P G  P        P GPP        
Sbjct: 56  KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP-----PGKPQGPPPQGDKSRS 110

Query: 61  PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109
           P +  G       +G   PQ PPP      PG       +G +  +GPP
Sbjct: 111 PRSPPGKPQGPPPQGGNQPQGPPPP-----PGKPQGPPPQGGNKPQGPP 154



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 37/117 (31%), Positives = 47/117 (40%), Gaps = 16/117 (13%)

Query: 3   KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPG-----PPAAA 55
           KPQ  P Q  ++PQ PPP       +P G   PP GG      +S +PPG     PP   
Sbjct: 262 KPQGPPPQGGNKPQGPPP-----PGKPQG--PPPQGG--SKSRSSRSPPGKPQGPPPQGG 312

Query: 56  SPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
           +   GP    G       +G   PQ PPP    + P       +R   +  G PQ P
Sbjct: 313 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGP 369



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 39/130 (30%), Positives = 47/130 (36%), Gaps = 24/130 (18%)

Query: 3   KPQPLQQPSQPQQPPPT--QQAVARRPPG--------GTSPPNGGLPGPLATSAAPP--- 49
           KPQ    P +PQ PPP   +    R PPG        G + P G  P P      PP   
Sbjct: 88  KPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 147

Query: 50  ----GPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQE------RPGAAAIGSA 99
               GPP    P  GP     +  R        PQ PPPQ   +       PG       
Sbjct: 148 NKPQGPPPPGKP-QGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 206

Query: 100 RGQSTGKGPP 109
           +G +  +GPP
Sbjct: 207 QGGNKPQGPP 216



 Score = 37.0 bits (84), Expect = 0.097
 Identities = 32/105 (30%), Positives = 39/105 (37%), Gaps = 9/105 (8%)

Query: 13  PQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRG 72
           PQ  PP      + PP     P G  P P   +  P GPP       GP    G    +G
Sbjct: 36  PQGAPPQGGNKPQGPPSPPGKPQG--PPPQGGN-QPQGPPPPPGKPQGP-PPQGGNKPQG 91

Query: 73  AEGILAPQPPPPQQHQER-----PGAAAIGSARGQSTGKGPPQSP 112
                 PQ PPPQ  + R     PG       +G +  +GPP  P
Sbjct: 92  PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP 136



 Score = 31.6 bits (70), Expect = 4.1
 Identities = 21/61 (34%), Positives = 24/61 (39%), Gaps = 12/61 (19%)

Query: 3   KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
           KPQ  P Q+ + PQ PP         PP G +P     P P      PP PP    P   
Sbjct: 365 KPQGPPQQEGNNPQGPP---------PPAGGNPQQPQAP-PAGQPQGPPRPPQGGRPSRP 414

Query: 61  P 61
           P
Sbjct: 415 P 415


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 162/677 (23%), Positives = 235/677 (34%), Gaps = 158/677 (23%)

Query: 375  GLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETS 434
            GL++    G       SP   +   G+    S++S + +R +  A  +S     P G  S
Sbjct: 15   GLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQI--AAVMSRAQGLPKG--S 70

Query: 435  VPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISP 494
            VPP  A        SP       + +S P        P  S   P      DPG     P
Sbjct: 71   VPPAAA-------ESPSMHRKQELDSSHP--------PKQSGRPP------DPG----RP 105

Query: 495  ASPKISLA-PTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKF----G 549
            A P +S +  TD      K PGR+  P  ++        L+  + R  L+E  K     G
Sbjct: 106  AQPGLSKSRTTDTFRSEQKLPGRS--PSTIS--------LKESKSRTDLKEEHKSSMMPG 155

Query: 550  AQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKED- 608
               ++   S+  + ++ F P  L  + +  ++E              ++K + V  KE  
Sbjct: 156  FLSEVNALSAVSSVVNKFNPFDLISDSEASQEE--------------TTKKQKVVQKEQG 201

Query: 609  ------KPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPN 662
                  KPPL         +QPP P P Q G        G D    P+ +     +++  
Sbjct: 202  KPEGIIKPPLQ--------QQPPKPIPKQQG-------PGRD----PLQQDGTPKSISSQ 242

Query: 663  AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722
              E   ++P     K    PT      H+   +P+           Q  +  PQ      
Sbjct: 243  QPEKIKSQP-PGTGKPIQGPTQTPQTDHA--KLPL-----------QRDASRPQTKQADI 288

Query: 723  VQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAAT 782
            V+   + P   S S P  Q    G   +  P   ++ QP  A P  Q +    P  +A  
Sbjct: 289  VRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGH-EKSQPGPAKPPAQPSGLTKP--LAQQ 345

Query: 783  PYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQY 842
            P +   P  P   PG            ++P   P+  + P    +GS           + 
Sbjct: 346  PGTVKPPVQP---PG-----------TTKPPAQPLGPAKPPAQQTGS-----------EK 380

Query: 843  PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAG-QA 901
            PS+EQP P+AL      + P    +  A QP PA  PT      Q   P P+  Q G Q+
Sbjct: 381  PSSEQPGPKAL------AQPPGVGKTPAQQPGPAKPPT-----QQVGTPKPLAQQPGLQS 429

Query: 902  PHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMA 961
            P    G  +  +  PG   G  P+   GP   S Q + P           QLP       
Sbjct: 430  PAKAPGPTKTPVQQPG--PGKIPAQQAGPGKTSAQQTGPTKPP------SQLP------G 475

Query: 962  HVTQAHVQTGITAAPPPHPGAPHPP--QVMLLHPPQSHGGPPQGAVPQSGVPALSASTPS 1019
                   Q G    PP  PG+  PP  Q     PP    GP + +  Q G    S   PS
Sbjct: 476  PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPG----STKPPS 531

Query: 1020 PYPYIGHPQAPLPPPGE 1036
              P    P A  P P +
Sbjct: 532  QQPGSAKPSAQQPSPAK 548



 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 157/690 (22%), Positives = 231/690 (33%), Gaps = 123/690 (17%)

Query: 333  QGSGRESPSLASREGKYIPLPQRVREGPR---GGVRCSSSRGG-------RPGLSSLPPR 382
            Q +G E PS      K +  P  V + P    G  +  + + G       +PGL S P +
Sbjct: 374  QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQS-PAK 432

Query: 383  --GPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGET--SVPPP 438
              GP       PGPG +      GP + S +   P +    L  P+  P  +   + PPP
Sbjct: 433  APGPTKTPVQQPGPG-KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPP 491

Query: 439  PAVGRMYPP-----------RSPKSAAPAPISASCPEPPI---GSAVPTSSASIPV---- 480
               G   PP           + P  A P+P      +PP    GSA P++    P     
Sbjct: 492  QQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSA 551

Query: 481  ---TSSVSDPGVG------SISPAS--------PK--ISLAPTDVKELSTKEPGRTLEPQ 521
               T  VS  G G      ++SP++        PK    L  T    L   E        
Sbjct: 552  QQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCT 611

Query: 522  ELARIAGKVPGLQNEQKRFQLEELRKFGAQFK------LQP-SSSPENSLDPFP----PR 570
            E       + G        +++E      Q K      L P  SSP+  L   P      
Sbjct: 612  ECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSA 671

Query: 571  ILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEG-----PEQPP 625
            + K  P+ ++       TS    +          + +  PPL       G      +QPP
Sbjct: 672  VSKSSPQPQQ-------TSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724

Query: 626  PPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSP 685
                    +PP       ++D+ PVA+   K       K   PT  L+S + +T+ P  P
Sbjct: 725  EADSLSKPAPPKEPSVPSEQDKAPVADDKPK-----QPKMVKPTTDLVSSSSATTKPDIP 779

Query: 686  GPRTHS------TPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPG 739
              +  S      TP +   +A  S  + P      P      A+  P      +S+  PG
Sbjct: 780  SSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSP--FDSKAIPRPASDSKIISH--PG 835

Query: 740  QQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQP 799
               + +G K   P Q+ +  +P  A   M     A P      P  S  P  P+   GQ 
Sbjct: 836  PSSESKGQKQVDPVQKKE--EPKKAQTKMSPKPDAKP-----MPKGSPTPPGPRPTAGQT 888

Query: 800  AMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQ 859
                  +  P +       QS    L  GS     ++ +    P+  Q T          
Sbjct: 889  VPTPQQSPKPQE-------QSRRFSLNLGS-----ITDAPKSQPTTPQETVTGKLFGFGA 936

Query: 860  SYPHHATQL--HAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPG 917
            S    A+ L   A QP P +      P  Q  AP+P Q    Q P   +GQ         
Sbjct: 937  SIFSQASNLISTAGQPGPHSQSGPGAPMKQ--APAPSQPPTSQGPPKSTGQ--------- 985

Query: 918  ALTGTPPSLPPGPSAQSPQSSFPQPAAVYA 947
            A      S+P     ++P +   +P A  A
Sbjct: 986  APPAPAKSIPVKKETKAPAAEKLEPKAEQA 1015



 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 150/687 (21%), Positives = 207/687 (30%), Gaps = 145/687 (21%)

Query: 405  PSRMSPKAQRPLRG-----AKTLSSPSNRPSGETSVPP---PPAVGRMYPPRSPKSAAPA 456
            P +  PK Q P R          S  S +P    S PP    P  G    P++  +  P 
Sbjct: 215  PPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPL 274

Query: 457  PISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGR 516
               AS P+      V   S   P   S S P +   +P  P       +  +    +P  
Sbjct: 275  QRDASRPQTKQADIVRGESVK-PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP-- 331

Query: 517  TLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEP 576
              +P  L +   + PG    +   Q     K  AQ  L P+  P        P   +  P
Sbjct: 332  PAQPSGLTKPLAQQPG--TVKPPVQPPGTTKPPAQ-PLGPAKPPAQQTGSEKPSSEQPGP 388

Query: 577  KGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPP 636
            K   +      T      P    T+ V   +   PLA   G + P + P P  +    P 
Sbjct: 389  KALAQPPGVGKTPAQQPGPAKPPTQQVGTPK---PLAQQPGLQSPAKAPGPTKTPVQQPG 445

Query: 637  VGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIP 696
             G I  +    G             +A++  PTKP   +         PGP         
Sbjct: 446  PGKIPAQQAGPG-----------KTSAQQTGPTKPPSQL---------PGP--------- 476

Query: 697  VLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRS 756
                           +  P    GPA   PQ    P S   P QQ       GS  P   
Sbjct: 477  ---------------AKPPPQQPGPAKPPPQQ---PGSAKPPSQQ------PGSTKP--- 509

Query: 757  DQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAP 816
               QP  A P  Q   +  PP                    QP   +P A  PS    + 
Sbjct: 510  PPQQPGPAKPSPQQPGSTKPP------------------SQQPGSAKPSAQQPSPAKPSA 551

Query: 817  MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPA 876
               + P   T    P    + S    PSA+QP  Q L  T+      + T+L  H P+ A
Sbjct: 552  QQSTKPVSQTGSGKPLQPPTVS----PSAKQPPSQGLPKTICPLC--NTTELLLHVPEKA 605

Query: 877  TTPTGSQPQSQHAA-----PSPVQHQAGQ----------------APHLGSGQPQQNLYH 915
               T ++ Q+   +     P+P   +  +                AP   S QP+     
Sbjct: 606  NFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKT-A 664

Query: 916  PGALTGTPPSLPPGPSAQSPQ---------SSFPQPAAVYAIHHQQLPHGFTNMAHVTQA 966
            P   T       P P   SP+         S  P+P     +  Q   HG  +       
Sbjct: 665  PVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724

Query: 967  HVQTGITAAPPPHPGAP-----------HPPQVMLLHPP----QSHGGPPQGAVPQSGV- 1010
               +    APP  P  P            P Q  ++ P      S     +  +P S V 
Sbjct: 725  EADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQ 784

Query: 1011 -PALSASTPSPYPYIGHPQAPLPPPGE 1036
              A   +TP        P    PP GE
Sbjct: 785  SQAEEKTTPPLKTDSAKPSQSFPPTGE 811



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 99/449 (22%), Positives = 159/449 (35%), Gaps = 78/449 (17%)

Query: 373  RPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGE 432
            +P L + P      +  SSP P   +   +  P +   KA  P +    +  P+   S  
Sbjct: 658  QPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPS 717

Query: 433  TSVPPPPAVGRMYPPRSPKSAA------PAPISASCPEPPIGSAVPTSSASIPVTSSVSD 486
                 PP    +  P  PK  +       AP++   P+ P    V  ++  +  +S+ + 
Sbjct: 718  AKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQP--KMVKPTTDLVSSSSATTK 775

Query: 487  PGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELR 546
            P + S    S         +K  S K P ++  P                      E++ 
Sbjct: 776  PDIPSSKVQSQAEEKTTPPLKTDSAK-PSQSFPPTG--------------------EKVS 814

Query: 547  KFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDK 606
             F ++   +P+S  +    P P      E KG +K+VD +   E    P  ++T+ +S K
Sbjct: 815  PFDSKAIPRPASDSKIISHPGP----SSESKG-QKQVDPVQKKE---EPKKAQTK-MSPK 865

Query: 607  EDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN----PN 662
             D  P+ P G       P PP P  T    V   +   K +    EQ ++ +LN     +
Sbjct: 866  PDAKPM-PKG------SPTPPGPRPTAGQTVPTPQQSPKPQ----EQSRRFSLNLGSITD 914

Query: 663  AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722
            A +  PT P  +V   T      G    S  S  + TAGQ G +S             P 
Sbjct: 915  APKSQPTTPQETV---TGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG-------APM 964

Query: 723  VQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPAS---------APPMMQAAAA 773
             QAP     P S   P   G+   A     P + +   PA+         AP + +    
Sbjct: 965  KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETE 1024

Query: 774  AGPPLV------AATPYSSYIPYNPQQFP 796
              PP +       A P  + +P   ++ P
Sbjct: 1025 KKPPPIKDSKSLTAEPQKAVLPTKLEKSP 1053



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 42/119 (35%), Positives = 53/119 (44%), Gaps = 17/119 (14%)

Query: 6   PLQQPSQPQQPPPTQQAVARRP----PGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
           P QQP   +  PPTQQ    +P    PG  SP     PGP  T    PGP    +   GP
Sbjct: 401 PAQQPGPAK--PPTQQVGTPKPLAQQPGLQSPAKA--PGPTKTPVQQPGPGKIPAQQAGP 456

Query: 62  --VAAAGSGLRRGAEGILAPQPPPPQQ------HQERPGAAAIGSARGQSTGKGPPQSP 112
              +A  +G  +    +  P  PPPQQ        ++PG+A   S +  ST K PPQ P
Sbjct: 457 GKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGST-KPPPQQP 514



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 39/119 (32%), Positives = 45/119 (37%), Gaps = 30/119 (25%)

Query: 6   PLQQPSQPQQPPPTQQAVARRPPGGTSPP--NGGLPGPLA----TSAAPPGPPAAASPCL 59
           P+QQP+ P +PP  Q    +  PG   PP    GL  PLA    T   P  PP    P  
Sbjct: 305 PIQQPT-PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363

Query: 60  GPVAAAGSGLRRGAEGILAPQPPPPQQ------HQERPGAAAIGSARGQSTGKGPPQSP 112
            P               L P  PP QQ        E+PG  A+    G   GK P Q P
Sbjct: 364 QP---------------LGPAKPPAQQTGSEKPSSEQPGPKALAQPPG--VGKTPAQQP 405



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 108/477 (22%), Positives = 160/477 (33%), Gaps = 62/477 (12%)

Query: 572  LKEEPKGKEKEVDGLLTSEPMGS--PVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPC- 628
            L EE + +   V       P GS  P ++++ S+  K++     P   +  P  P  P  
Sbjct: 48   LSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQ 107

Query: 629  PSQTGSPPVGLIKGEDKDEG--PVAEQVKKSTLNPNAKEFNPTKPL---LSVNKSTSTPT 683
            P  + S      + E K  G  P    +K+S    + KE + +  +   LS   + S  +
Sbjct: 108  PGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVS 167

Query: 684  SPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK 743
            S   + +    I    A Q      Q +    Q      ++ P     P    +P QQG 
Sbjct: 168  SVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPP--KPIPKQQGP 225

Query: 744  YRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYN-PQQFPGQPAMM 802
             R           D  Q    P   ++ ++  P  + + P  +  P   P Q P      
Sbjct: 226  GR-----------DPLQQDGTP---KSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAK 271

Query: 803  QPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYP 862
             P+    S+P      Q+    +  G   +  + S  P  P  +QPTP    A      P
Sbjct: 272  LPLQRDASRP------QTKQADIVRGESVKPSLPS--PSKPPIQQPTPGKPPA----QQP 319

Query: 863  HHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGT 922
             H       QP PA  P         A PS +     Q P    G  +  +  PG  T  
Sbjct: 320  GHEKS----QPGPAKPP---------AQPSGLTKPLAQQP----GTVKPPVQPPG--TTK 360

Query: 923  PPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHP-G 981
            PP+ P GP+    Q +  +  +      Q  P        V +   Q    A PP    G
Sbjct: 361  PPAQPLGPAKPPAQQTGSEKPS----SEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVG 416

Query: 982  APHP-PQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQAPLPPPGEL 1037
             P P  Q   L  P    GP +  V Q G   + A    P         P  PP +L
Sbjct: 417  TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQL 473



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 34/101 (33%), Positives = 41/101 (40%), Gaps = 16/101 (15%)

Query: 3   KPQPLQQPSQPQQPPPTQQAVARRP---PGGTSPPNGGLPGPLATSAAPPGPPAAASPCL 59
           KP P QQP  P +PPP Q   A+ P   PG T PP    PGP   S   PG  +   P  
Sbjct: 478 KPPP-QQPG-PAKPPPQQPGSAKPPSQQPGSTKPPPQQ-PGPAKPSPQQPG--STKPPSQ 532

Query: 60  GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSAR 100
            P +A  S  +        P P  P   Q     +  GS +
Sbjct: 533 QPGSAKPSAQQ--------PSPAKPSAQQSTKPVSQTGSGK 565



 Score = 37.7 bits (86), Expect = 0.057
 Identities = 31/83 (37%), Positives = 38/83 (45%), Gaps = 8/83 (9%)

Query: 6   PLQQPSQPQQPPPTQQAVAR---RPPGGTSPPNGGLPGPLATSAAPPGP-PAAASPCLGP 61
           P QQP   + PPP Q   A+   + PG T PP+   PG    SA  P P   +A     P
Sbjct: 500 PSQQPGSTK-PPPQQPGPAKPSPQQPGSTKPPS-QQPGSAKPSAQQPSPAKPSAQQSTKP 557

Query: 62  VAAAGSG--LRRGAEGILAPQPP 82
           V+  GSG  L+       A QPP
Sbjct: 558 VSQTGSGKPLQPPTVSPSAKQPP 580



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 36/112 (32%), Positives = 45/112 (40%), Gaps = 13/112 (11%)

Query: 6   PLQQPSQ---PQQPPPTQQAVARRPP--GGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
           P + PSQ   P +PPP Q   A+ PP   G++ P    PG        PG PA  SP   
Sbjct: 466 PTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPG-PAKPSP-QQ 523

Query: 61  PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
           P +      + G+    A QP P      +P A        Q TG G P  P
Sbjct: 524 PGSTKPPSQQPGSAKPSAQQPSP-----AKPSAQQSTKPVSQ-TGSGKPLQP 569



 Score = 35.4 bits (80), Expect = 0.28
 Identities = 34/114 (29%), Positives = 46/114 (40%), Gaps = 12/114 (10%)

Query: 4   PQPLQQPSQPQQPP--PTQQA----VARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASP 57
           P P + P Q   P   P QQA     + +  G T PP+  LPGP       PGP  A  P
Sbjct: 434 PGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ-LPGPAKPPPQQPGP--AKPP 490

Query: 58  CLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111
              P +A     + G+      QP P +   ++PG+    S   Q  G   P +
Sbjct: 491 PQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS---QQPGSAKPSA 541



 Score = 35.4 bits (80), Expect = 0.28
 Identities = 61/265 (23%), Positives = 101/265 (38%), Gaps = 51/265 (19%)

Query: 390  SSPGPGSEARGINGGPSRMSP--KAQRPLRGAKTLS-SPSNRPSGETSVPPP---PAVGR 443
            S PGP SE++G      ++ P  K + P +    +S  P  +P  + S  PP   P  G+
Sbjct: 832  SHPGPSSESKG----QKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQ 887

Query: 444  MYPP--RSPK-------------SAAPAPISA-SCPEPPIGSAVPTSSASI-----PVTS 482
              P   +SPK             S   AP S  + P+  +   +    ASI      + S
Sbjct: 888  TVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947

Query: 483  SVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQL 542
            +   PG  S S     +  AP   +  +++ P ++          G+ P      K   +
Sbjct: 948  TAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKS---------TGQAPPAP--AKSIPV 996

Query: 543  EELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGL--LTSEPMGSPVSSKT 600
            ++  K  A  KL+P +          P + + E + K   +     LT+EP  + + +K 
Sbjct: 997  KKETKAPAAEKLEPKAEQA-------PTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKL 1049

Query: 601  ESVSDKEDKPPLAPSGGTEGPEQPP 625
            E     E   PL  +    G + PP
Sbjct: 1050 EKSPKPESTCPLCKTELNIGSKDPP 1074



 Score = 34.7 bits (78), Expect = 0.48
 Identities = 37/128 (28%), Positives = 47/128 (36%), Gaps = 28/128 (21%)

Query: 3   KPQPLQQPSQP--------QQP----PPTQQAVARRPP----GGTSPPNGGLPGPLATSA 46
           +P P + P+QP        QQP    PP Q     +PP    G   PP     G    S+
Sbjct: 325 QPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP-AQQTGSEKPSS 383

Query: 47  APPGPPAAAS-PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTG 105
             PGP A A  P +G   A   G          P  PP QQ       A     +  +  
Sbjct: 384 EQPGPKALAQPPGVGKTPAQQPG----------PAKPPTQQVGTPKPLAQQPGLQSPAKA 433

Query: 106 KGPPQSPV 113
            GP ++PV
Sbjct: 434 PGPTKTPV 441



 Score = 31.2 bits (69), Expect = 5.3
 Identities = 36/138 (26%), Positives = 48/138 (34%), Gaps = 15/138 (10%)

Query: 575  EPKGKEKEVDGLLTSEPMGSPV---------SSKTESVSDKEDKPPLAPSGGTEGPEQPP 625
            E  G+EK    L +  P  S +         SS  +  +     PP  P      P  PP
Sbjct: 2365 ETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPP 2424

Query: 626  PPCPSQTGSPPVGLIKGEDKDEGPVAEQV----KKSTLNPNAKEFNPTKPLLSVNKSTST 681
            PP P  T   P  L K +     PV          +TL   A   +   P+  +   T+ 
Sbjct: 2425 PPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRI--CTTA 2482

Query: 682  PTSPGPRTHSTPSIPVLT 699
            P    P+  S PS  V T
Sbjct: 2483 PPPVPPKPSSIPSGLVFT 2500



 Score = 30.4 bits (67), Expect = 9.1
 Identities = 28/122 (22%), Positives = 53/122 (43%), Gaps = 11/122 (9%)

Query: 533  LQNEQKRFQLEELRKFGAQFKLQP---SSSPENSLDPFPPRILKEEPKGKEKEVDGLLTS 589
            +++E+K+  LEE +      KL P   +S+PE         +LK + +  E++++G +  
Sbjct: 1227 IRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHD----LLKSQVQIAEEKLEGRVAP 1282

Query: 590  EPMGSPVSSKTESVSDKEDKPPLAPSGGTEGP----EQPPPPCPSQTGSPPVGLIKGEDK 645
            + +      +T+        P   P    +      EQP PPC ++      G  K E +
Sbjct: 1283 KTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKE 1342

Query: 646  DE 647
            D+
Sbjct: 1343 DD 1344



 Score = 30.4 bits (67), Expect = 9.1
 Identities = 38/155 (24%), Positives = 57/155 (36%), Gaps = 18/155 (11%)

Query: 534  QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593
            + E K+ +    R  G        SS E  L      +LKE+ K +E E           
Sbjct: 1749 KGESKQQRKARHRPHGPLLPTIEDSSEEEELRE-EEELLKEQEKQREIEQQ--------- 1798

Query: 594  SPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP-CPSQTGSPPVGLIKGEDKDE---GP 649
                 K+ S   K+DK  L      E P+ PP    P +  SP   L +  + +E     
Sbjct: 1799 ---QRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSS 1855

Query: 650  VAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTS 684
             +E       +P   E +P K ++ V K    PT+
Sbjct: 1856 CSEYSPSIESDPEGFEISPEK-IIEVQKVYKLPTA 1889


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 162/677 (23%), Positives = 235/677 (34%), Gaps = 158/677 (23%)

Query: 375  GLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETS 434
            GL++    G       SP   +   G+    S++S + +R +  A  +S     P G  S
Sbjct: 15   GLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQI--AAVMSRAQGLPKG--S 70

Query: 435  VPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISP 494
            VPP  A        SP       + +S P        P  S   P      DPG     P
Sbjct: 71   VPPAAA-------ESPSMHRKQELDSSHP--------PKQSGRPP------DPG----RP 105

Query: 495  ASPKISLA-PTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKF----G 549
            A P +S +  TD      K PGR+  P  ++        L+  + R  L+E  K     G
Sbjct: 106  AQPGLSKSRTTDTFRSEQKLPGRS--PSTIS--------LKESKSRTDLKEEHKSSMMPG 155

Query: 550  AQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKED- 608
               ++   S+  + ++ F P  L  + +  ++E              ++K + V  KE  
Sbjct: 156  FLSEVNALSAVSSVVNKFNPFDLISDSEASQEE--------------TTKKQKVVQKEQG 201

Query: 609  ------KPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPN 662
                  KPPL         +QPP P P Q G        G D    P+ +     +++  
Sbjct: 202  KPEGIIKPPLQ--------QQPPKPIPKQQG-------PGRD----PLQQDGTPKSISSQ 242

Query: 663  AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722
              E   ++P     K    PT      H+   +P+           Q  +  PQ      
Sbjct: 243  QPEKIKSQP-PGTGKPIQGPTQTPQTDHA--KLPL-----------QRDASRPQTKQADI 288

Query: 723  VQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAAT 782
            V+   + P   S S P  Q    G   +  P   ++ QP  A P  Q +    P  +A  
Sbjct: 289  VRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGH-EKSQPGPAKPPAQPSGLTKP--LAQQ 345

Query: 783  PYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQY 842
            P +   P  P   PG            ++P   P+  + P    +GS           + 
Sbjct: 346  PGTVKPPVQP---PG-----------TTKPPAQPLGPAKPPAQQTGS-----------EK 380

Query: 843  PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAG-QA 901
            PS+EQP P+AL      + P    +  A QP PA  PT      Q   P P+  Q G Q+
Sbjct: 381  PSSEQPGPKAL------AQPPGVGKTPAQQPGPAKPPT-----QQVGTPKPLAQQPGLQS 429

Query: 902  PHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMA 961
            P    G  +  +  PG   G  P+   GP   S Q + P           QLP       
Sbjct: 430  PAKAPGPTKTPVQQPG--PGKIPAQQAGPGKTSAQQTGPTKPP------SQLP------G 475

Query: 962  HVTQAHVQTGITAAPPPHPGAPHPP--QVMLLHPPQSHGGPPQGAVPQSGVPALSASTPS 1019
                   Q G    PP  PG+  PP  Q     PP    GP + +  Q G    S   PS
Sbjct: 476  PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPG----STKPPS 531

Query: 1020 PYPYIGHPQAPLPPPGE 1036
              P    P A  P P +
Sbjct: 532  QQPGSAKPSAQQPSPAK 548



 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 157/690 (22%), Positives = 231/690 (33%), Gaps = 123/690 (17%)

Query: 333  QGSGRESPSLASREGKYIPLPQRVREGPR---GGVRCSSSRGG-------RPGLSSLPPR 382
            Q +G E PS      K +  P  V + P    G  +  + + G       +PGL S P +
Sbjct: 374  QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQS-PAK 432

Query: 383  --GPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGET--SVPPP 438
              GP       PGPG +      GP + S +   P +    L  P+  P  +   + PPP
Sbjct: 433  APGPTKTPVQQPGPG-KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPP 491

Query: 439  PAVGRMYPP-----------RSPKSAAPAPISASCPEPPI---GSAVPTSSASIPV---- 480
               G   PP           + P  A P+P      +PP    GSA P++    P     
Sbjct: 492  QQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSA 551

Query: 481  ---TSSVSDPGVG------SISPAS--------PK--ISLAPTDVKELSTKEPGRTLEPQ 521
               T  VS  G G      ++SP++        PK    L  T    L   E        
Sbjct: 552  QQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCT 611

Query: 522  ELARIAGKVPGLQNEQKRFQLEELRKFGAQFK------LQP-SSSPENSLDPFP----PR 570
            E       + G        +++E      Q K      L P  SSP+  L   P      
Sbjct: 612  ECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSA 671

Query: 571  ILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEG-----PEQPP 625
            + K  P+ ++       TS    +          + +  PPL       G      +QPP
Sbjct: 672  VSKSSPQPQQ-------TSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724

Query: 626  PPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSP 685
                    +PP       ++D+ PVA+   K       K   PT  L+S + +T+ P  P
Sbjct: 725  EADSLSKPAPPKEPSVPSEQDKAPVADDKPK-----QPKMVKPTTDLVSSSSATTKPDIP 779

Query: 686  GPRTHS------TPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPG 739
              +  S      TP +   +A  S  + P      P      A+  P      +S+  PG
Sbjct: 780  SSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSP--FDSKAIPRPASDSKIISH--PG 835

Query: 740  QQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQP 799
               + +G K   P Q+ +  +P  A   M     A P      P  S  P  P+   GQ 
Sbjct: 836  PSSESKGQKQVDPVQKKE--EPKKAQTKMSPKPDAKP-----MPKGSPTPPGPRPTAGQT 888

Query: 800  AMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQ 859
                  +  P +       QS    L  GS     ++ +    P+  Q T          
Sbjct: 889  VPTPQQSPKPQE-------QSRRFSLNLGS-----ITDAPKSQPTTPQETVTGKLFGFGA 936

Query: 860  SYPHHATQL--HAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPG 917
            S    A+ L   A QP P +      P  Q  AP+P Q    Q P   +GQ         
Sbjct: 937  SIFSQASNLISTAGQPGPHSQSGPGAPMKQ--APAPSQPPTSQGPPKSTGQ--------- 985

Query: 918  ALTGTPPSLPPGPSAQSPQSSFPQPAAVYA 947
            A      S+P     ++P +   +P A  A
Sbjct: 986  APPAPAKSIPVKKETKAPAAEKLEPKAEQA 1015



 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 150/687 (21%), Positives = 207/687 (30%), Gaps = 145/687 (21%)

Query: 405  PSRMSPKAQRPLRG-----AKTLSSPSNRPSGETSVPP---PPAVGRMYPPRSPKSAAPA 456
            P +  PK Q P R          S  S +P    S PP    P  G    P++  +  P 
Sbjct: 215  PPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPL 274

Query: 457  PISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGR 516
               AS P+      V   S   P   S S P +   +P  P       +  +    +P  
Sbjct: 275  QRDASRPQTKQADIVRGESVK-PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP-- 331

Query: 517  TLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEP 576
              +P  L +   + PG    +   Q     K  AQ  L P+  P        P   +  P
Sbjct: 332  PAQPSGLTKPLAQQPG--TVKPPVQPPGTTKPPAQ-PLGPAKPPAQQTGSEKPSSEQPGP 388

Query: 577  KGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPP 636
            K   +      T      P    T+ V   +   PLA   G + P + P P  +    P 
Sbjct: 389  KALAQPPGVGKTPAQQPGPAKPPTQQVGTPK---PLAQQPGLQSPAKAPGPTKTPVQQPG 445

Query: 637  VGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIP 696
             G I  +    G             +A++  PTKP   +         PGP         
Sbjct: 446  PGKIPAQQAGPG-----------KTSAQQTGPTKPPSQL---------PGP--------- 476

Query: 697  VLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRS 756
                           +  P    GPA   PQ    P S   P QQ       GS  P   
Sbjct: 477  ---------------AKPPPQQPGPAKPPPQQ---PGSAKPPSQQ------PGSTKP--- 509

Query: 757  DQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAP 816
               QP  A P  Q   +  PP                    QP   +P A  PS    + 
Sbjct: 510  PPQQPGPAKPSPQQPGSTKPP------------------SQQPGSAKPSAQQPSPAKPSA 551

Query: 817  MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPA 876
               + P   T    P    + S    PSA+QP  Q L  T+      + T+L  H P+ A
Sbjct: 552  QQSTKPVSQTGSGKPLQPPTVS----PSAKQPPSQGLPKTICPLC--NTTELLLHVPEKA 605

Query: 877  TTPTGSQPQSQHAA-----PSPVQHQAGQ----------------APHLGSGQPQQNLYH 915
               T ++ Q+   +     P+P   +  +                AP   S QP+     
Sbjct: 606  NFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKT-A 664

Query: 916  PGALTGTPPSLPPGPSAQSPQ---------SSFPQPAAVYAIHHQQLPHGFTNMAHVTQA 966
            P   T       P P   SP+         S  P+P     +  Q   HG  +       
Sbjct: 665  PVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724

Query: 967  HVQTGITAAPPPHPGAP-----------HPPQVMLLHPP----QSHGGPPQGAVPQSGV- 1010
               +    APP  P  P            P Q  ++ P      S     +  +P S V 
Sbjct: 725  EADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQ 784

Query: 1011 -PALSASTPSPYPYIGHPQAPLPPPGE 1036
              A   +TP        P    PP GE
Sbjct: 785  SQAEEKTTPPLKTDSAKPSQSFPPTGE 811



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 99/449 (22%), Positives = 159/449 (35%), Gaps = 78/449 (17%)

Query: 373  RPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGE 432
            +P L + P      +  SSP P   +   +  P +   KA  P +    +  P+   S  
Sbjct: 658  QPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPS 717

Query: 433  TSVPPPPAVGRMYPPRSPKSAA------PAPISASCPEPPIGSAVPTSSASIPVTSSVSD 486
                 PP    +  P  PK  +       AP++   P+ P    V  ++  +  +S+ + 
Sbjct: 718  AKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQP--KMVKPTTDLVSSSSATTK 775

Query: 487  PGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELR 546
            P + S    S         +K  S K P ++  P                      E++ 
Sbjct: 776  PDIPSSKVQSQAEEKTTPPLKTDSAK-PSQSFPPTG--------------------EKVS 814

Query: 547  KFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDK 606
             F ++   +P+S  +    P P      E KG +K+VD +   E    P  ++T+ +S K
Sbjct: 815  PFDSKAIPRPASDSKIISHPGP----SSESKG-QKQVDPVQKKE---EPKKAQTK-MSPK 865

Query: 607  EDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN----PN 662
             D  P+ P G       P PP P  T    V   +   K +    EQ ++ +LN     +
Sbjct: 866  PDAKPM-PKG------SPTPPGPRPTAGQTVPTPQQSPKPQ----EQSRRFSLNLGSITD 914

Query: 663  AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722
            A +  PT P  +V   T      G    S  S  + TAGQ G +S             P 
Sbjct: 915  APKSQPTTPQETV---TGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG-------APM 964

Query: 723  VQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPAS---------APPMMQAAAA 773
             QAP     P S   P   G+   A     P + +   PA+         AP + +    
Sbjct: 965  KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETE 1024

Query: 774  AGPPLV------AATPYSSYIPYNPQQFP 796
              PP +       A P  + +P   ++ P
Sbjct: 1025 KKPPPIKDSKSLTAEPQKAVLPTKLEKSP 1053



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 42/119 (35%), Positives = 53/119 (44%), Gaps = 17/119 (14%)

Query: 6   PLQQPSQPQQPPPTQQAVARRP----PGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
           P QQP   +  PPTQQ    +P    PG  SP     PGP  T    PGP    +   GP
Sbjct: 401 PAQQPGPAK--PPTQQVGTPKPLAQQPGLQSPAKA--PGPTKTPVQQPGPGKIPAQQAGP 456

Query: 62  --VAAAGSGLRRGAEGILAPQPPPPQQ------HQERPGAAAIGSARGQSTGKGPPQSP 112
              +A  +G  +    +  P  PPPQQ        ++PG+A   S +  ST K PPQ P
Sbjct: 457 GKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGST-KPPPQQP 514



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 39/119 (32%), Positives = 45/119 (37%), Gaps = 30/119 (25%)

Query: 6   PLQQPSQPQQPPPTQQAVARRPPGGTSPP--NGGLPGPLA----TSAAPPGPPAAASPCL 59
           P+QQP+ P +PP  Q    +  PG   PP    GL  PLA    T   P  PP    P  
Sbjct: 305 PIQQPT-PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363

Query: 60  GPVAAAGSGLRRGAEGILAPQPPPPQQ------HQERPGAAAIGSARGQSTGKGPPQSP 112
            P               L P  PP QQ        E+PG  A+    G   GK P Q P
Sbjct: 364 QP---------------LGPAKPPAQQTGSEKPSSEQPGPKALAQPPG--VGKTPAQQP 405



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 108/477 (22%), Positives = 160/477 (33%), Gaps = 62/477 (12%)

Query: 572  LKEEPKGKEKEVDGLLTSEPMGS--PVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPC- 628
            L EE + +   V       P GS  P ++++ S+  K++     P   +  P  P  P  
Sbjct: 48   LSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQ 107

Query: 629  PSQTGSPPVGLIKGEDKDEG--PVAEQVKKSTLNPNAKEFNPTKPL---LSVNKSTSTPT 683
            P  + S      + E K  G  P    +K+S    + KE + +  +   LS   + S  +
Sbjct: 108  PGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVS 167

Query: 684  SPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK 743
            S   + +    I    A Q      Q +    Q      ++ P     P    +P QQG 
Sbjct: 168  SVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPP--KPIPKQQGP 225

Query: 744  YRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYN-PQQFPGQPAMM 802
             R           D  Q    P   ++ ++  P  + + P  +  P   P Q P      
Sbjct: 226  GR-----------DPLQQDGTP---KSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAK 271

Query: 803  QPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYP 862
             P+    S+P      Q+    +  G   +  + S  P  P  +QPTP    A      P
Sbjct: 272  LPLQRDASRP------QTKQADIVRGESVKPSLPS--PSKPPIQQPTPGKPPA----QQP 319

Query: 863  HHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGT 922
             H       QP PA  P         A PS +     Q P    G  +  +  PG  T  
Sbjct: 320  GHEKS----QPGPAKPP---------AQPSGLTKPLAQQP----GTVKPPVQPPG--TTK 360

Query: 923  PPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHP-G 981
            PP+ P GP+    Q +  +  +      Q  P        V +   Q    A PP    G
Sbjct: 361  PPAQPLGPAKPPAQQTGSEKPS----SEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVG 416

Query: 982  APHP-PQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQAPLPPPGEL 1037
             P P  Q   L  P    GP +  V Q G   + A    P         P  PP +L
Sbjct: 417  TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQL 473



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 34/101 (33%), Positives = 41/101 (40%), Gaps = 16/101 (15%)

Query: 3   KPQPLQQPSQPQQPPPTQQAVARRP---PGGTSPPNGGLPGPLATSAAPPGPPAAASPCL 59
           KP P QQP  P +PPP Q   A+ P   PG T PP    PGP   S   PG  +   P  
Sbjct: 478 KPPP-QQPG-PAKPPPQQPGSAKPPSQQPGSTKPPPQQ-PGPAKPSPQQPG--STKPPSQ 532

Query: 60  GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSAR 100
            P +A  S  +        P P  P   Q     +  GS +
Sbjct: 533 QPGSAKPSAQQ--------PSPAKPSAQQSTKPVSQTGSGK 565



 Score = 37.7 bits (86), Expect = 0.057
 Identities = 31/83 (37%), Positives = 38/83 (45%), Gaps = 8/83 (9%)

Query: 6   PLQQPSQPQQPPPTQQAVAR---RPPGGTSPPNGGLPGPLATSAAPPGP-PAAASPCLGP 61
           P QQP   + PPP Q   A+   + PG T PP+   PG    SA  P P   +A     P
Sbjct: 500 PSQQPGSTK-PPPQQPGPAKPSPQQPGSTKPPS-QQPGSAKPSAQQPSPAKPSAQQSTKP 557

Query: 62  VAAAGSG--LRRGAEGILAPQPP 82
           V+  GSG  L+       A QPP
Sbjct: 558 VSQTGSGKPLQPPTVSPSAKQPP 580



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 36/112 (32%), Positives = 45/112 (40%), Gaps = 13/112 (11%)

Query: 6   PLQQPSQ---PQQPPPTQQAVARRPP--GGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
           P + PSQ   P +PPP Q   A+ PP   G++ P    PG        PG PA  SP   
Sbjct: 466 PTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPG-PAKPSP-QQ 523

Query: 61  PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
           P +      + G+    A QP P      +P A        Q TG G P  P
Sbjct: 524 PGSTKPPSQQPGSAKPSAQQPSP-----AKPSAQQSTKPVSQ-TGSGKPLQP 569



 Score = 35.4 bits (80), Expect = 0.28
 Identities = 34/114 (29%), Positives = 46/114 (40%), Gaps = 12/114 (10%)

Query: 4   PQPLQQPSQPQQPP--PTQQA----VARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASP 57
           P P + P Q   P   P QQA     + +  G T PP+  LPGP       PGP  A  P
Sbjct: 434 PGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ-LPGPAKPPPQQPGP--AKPP 490

Query: 58  CLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111
              P +A     + G+      QP P +   ++PG+    S   Q  G   P +
Sbjct: 491 PQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS---QQPGSAKPSA 541



 Score = 35.4 bits (80), Expect = 0.28
 Identities = 61/265 (23%), Positives = 101/265 (38%), Gaps = 51/265 (19%)

Query: 390  SSPGPGSEARGINGGPSRMSP--KAQRPLRGAKTLS-SPSNRPSGETSVPPP---PAVGR 443
            S PGP SE++G      ++ P  K + P +    +S  P  +P  + S  PP   P  G+
Sbjct: 832  SHPGPSSESKG----QKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQ 887

Query: 444  MYPP--RSPK-------------SAAPAPISA-SCPEPPIGSAVPTSSASI-----PVTS 482
              P   +SPK             S   AP S  + P+  +   +    ASI      + S
Sbjct: 888  TVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947

Query: 483  SVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQL 542
            +   PG  S S     +  AP   +  +++ P ++          G+ P      K   +
Sbjct: 948  TAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKS---------TGQAPPAP--AKSIPV 996

Query: 543  EELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGL--LTSEPMGSPVSSKT 600
            ++  K  A  KL+P +          P + + E + K   +     LT+EP  + + +K 
Sbjct: 997  KKETKAPAAEKLEPKAEQA-------PTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKL 1049

Query: 601  ESVSDKEDKPPLAPSGGTEGPEQPP 625
            E     E   PL  +    G + PP
Sbjct: 1050 EKSPKPESTCPLCKTELNIGSKDPP 1074



 Score = 34.7 bits (78), Expect = 0.48
 Identities = 37/128 (28%), Positives = 47/128 (36%), Gaps = 28/128 (21%)

Query: 3   KPQPLQQPSQP--------QQP----PPTQQAVARRPP----GGTSPPNGGLPGPLATSA 46
           +P P + P+QP        QQP    PP Q     +PP    G   PP     G    S+
Sbjct: 325 QPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP-AQQTGSEKPSS 383

Query: 47  APPGPPAAAS-PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTG 105
             PGP A A  P +G   A   G          P  PP QQ       A     +  +  
Sbjct: 384 EQPGPKALAQPPGVGKTPAQQPG----------PAKPPTQQVGTPKPLAQQPGLQSPAKA 433

Query: 106 KGPPQSPV 113
            GP ++PV
Sbjct: 434 PGPTKTPV 441



 Score = 31.2 bits (69), Expect = 5.3
 Identities = 36/138 (26%), Positives = 48/138 (34%), Gaps = 15/138 (10%)

Query: 575  EPKGKEKEVDGLLTSEPMGSPV---------SSKTESVSDKEDKPPLAPSGGTEGPEQPP 625
            E  G+EK    L +  P  S +         SS  +  +     PP  P      P  PP
Sbjct: 2365 ETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPP 2424

Query: 626  PPCPSQTGSPPVGLIKGEDKDEGPVAEQV----KKSTLNPNAKEFNPTKPLLSVNKSTST 681
            PP P  T   P  L K +     PV          +TL   A   +   P+  +   T+ 
Sbjct: 2425 PPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRI--CTTA 2482

Query: 682  PTSPGPRTHSTPSIPVLT 699
            P    P+  S PS  V T
Sbjct: 2483 PPPVPPKPSSIPSGLVFT 2500



 Score = 30.4 bits (67), Expect = 9.1
 Identities = 28/122 (22%), Positives = 53/122 (43%), Gaps = 11/122 (9%)

Query: 533  LQNEQKRFQLEELRKFGAQFKLQP---SSSPENSLDPFPPRILKEEPKGKEKEVDGLLTS 589
            +++E+K+  LEE +      KL P   +S+PE         +LK + +  E++++G +  
Sbjct: 1227 IRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHD----LLKSQVQIAEEKLEGRVAP 1282

Query: 590  EPMGSPVSSKTESVSDKEDKPPLAPSGGTEGP----EQPPPPCPSQTGSPPVGLIKGEDK 645
            + +      +T+        P   P    +      EQP PPC ++      G  K E +
Sbjct: 1283 KTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKE 1342

Query: 646  DE 647
            D+
Sbjct: 1343 DD 1344



 Score = 30.4 bits (67), Expect = 9.1
 Identities = 38/155 (24%), Positives = 57/155 (36%), Gaps = 18/155 (11%)

Query: 534  QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593
            + E K+ +    R  G        SS E  L      +LKE+ K +E E           
Sbjct: 1749 KGESKQQRKARHRPHGPLLPTIEDSSEEEELRE-EEELLKEQEKQREIEQQ--------- 1798

Query: 594  SPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP-CPSQTGSPPVGLIKGEDKDE---GP 649
                 K+ S   K+DK  L      E P+ PP    P +  SP   L +  + +E     
Sbjct: 1799 ---QRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSS 1855

Query: 650  VAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTS 684
             +E       +P   E +P K ++ V K    PT+
Sbjct: 1856 CSEYSPSIESDPEGFEISPEK-IIEVQKVYKLPTA 1889


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 74.3 bits (181), Expect = 6e-13
 Identities = 108/382 (28%), Positives = 135/382 (35%), Gaps = 83/382 (21%)

Query: 683  TSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQG 742
            T PGP   S P  P   +G + L  P+     P  H  P    P +YP P      G   
Sbjct: 780  TGPGPHYLSGPLPPGTYSGPTQLIQPR----APGPHAMPVAPGPALYPAPAYTPELG--- 832

Query: 743  KYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGP-PLVAATPYSSYIPYNPQQFPG-QPA 800
                    L P+ S QH   S+P +       GP P VA  P +      P QF G + A
Sbjct: 833  --------LVPRSSPQHGVVSSPYV-----GVGPAPPVAGLPSAP-----PPQFSGPELA 874

Query: 801  MMQPMAHYPSQPVFAPM-LQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQ 859
            M    A      + AP+   + PR   + + P        PQ      PTP    A   Q
Sbjct: 875  MAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQ----PLPTPYTYPAGAKQ 930

Query: 860  SYP---HHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHP 916
              P   H ++ + A  P P   P   QPQ  H  P P Q    Q P         +L+ P
Sbjct: 931  PIPAQHHFSSGIPAGFPAPRIGP---QPQP-HPQPHPSQAFGPQPPQQPLPLQHPHLFPP 986

Query: 917  GALTGTPPSLPPGPSAQSPQSSFPQPAAVYA----IHHQQLPHGFTNMAHVTQAHVQTGI 972
             A    P  LPP    QSP    PQP  +      +H Q  P          Q  +    
Sbjct: 987  QA----PGLLPP----QSPYPYAPQPGVLGQPPPPLHTQLYPGP-------AQDPLPAHS 1031

Query: 973  TAAPPPHPGAPHPPQVMLLHPPQSHG--------GPPQGAVPQSGVPALSASTPSPY--- 1021
             A P P PG P PP     HPP ++G        GP    +   G  +   STPSP+   
Sbjct: 1032 GALPFPSPGPPQPP-----HPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVP 1086

Query: 1022 ---------PYIGHPQAPLPPP 1034
                     P    P A  PPP
Sbjct: 1087 SPAPSPGPGPVPPRPPAAEPPP 1108



 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 103/406 (25%), Positives = 134/406 (33%), Gaps = 74/406 (18%)

Query: 670  KPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMY 729
            KPLL   + +    +  P        P + AG        ++     +H  P+       
Sbjct: 724  KPLLPRREESEAVEAGDPPEELRSLPPDMVAGPR--LPDTFLGSATPLHFPPSPFPSSTG 781

Query: 730  PYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIP 789
            P P   S P   G Y G    + P+    H    AP         GP L  A  Y+  + 
Sbjct: 782  PGPHYLSGPLPPGTYSGPTQLIQPRAPGPHAMPVAP---------GPALYPAPAYTPELG 832

Query: 790  YNPQQFPGQPAMMQ---------PMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
              P+  P    +           P+A  PS P   P   S P +  +       V S   
Sbjct: 833  LVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAP---PPQFSGPELAMAVRPATTTVDSIQA 889

Query: 841  QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQ---PQSQHAA------- 890
              PS   P P    A     +P    Q     P P T P G++   P   H +       
Sbjct: 890  PIPSHTAPRPNPTPAPPPPCFPVPPPQ---PLPTPYTYPAGAKQPIPAQHHFSSGIPAGF 946

Query: 891  PSP---VQHQAGQAPH----LGSGQPQQ--NLYHPGALTGTPPSLPPGPSAQSPQSSFPQ 941
            P+P    Q Q    PH     G   PQQ   L HP      PP  P     QSP    PQ
Sbjct: 947  PAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLF---PPQAPGLLPPQSPYPYAPQ 1003

Query: 942  PAAV----YAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSH 997
            P  +      +H Q  P          Q  +     A P P PG P PP     HPP ++
Sbjct: 1004 PGVLGQPPPPLHTQLYP-------GPAQDPLPAHSGALPFPSPGPPQPP-----HPPLAY 1051

Query: 998  G--------GPPQGAVPQSGVPALSASTPSPYPYIGHPQAPLPPPG 1035
            G        GP    +   G  +   STPS  P++    AP P PG
Sbjct: 1052 GPAPSTRPMGPQAAPLTIRGPSSAGQSTPS--PHLVPSPAPSPGPG 1095



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 93/372 (25%), Positives = 122/372 (32%), Gaps = 75/372 (20%)

Query: 610  PPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNP- 668
            P   PS    GP     P P  T S P  LI  + +  GP A  V        A  + P 
Sbjct: 773  PSPFPSSTGPGPHYLSGPLPPGTYSGPTQLI--QPRAPGPHAMPVAPGPALYPAPAYTPE 830

Query: 669  ------TKPLLSVNKSTSTPTSPGPRTHSTPSIPV--------------LTAGQSGLYSP 708
                  + P   V  S      P P     PS P                T     + +P
Sbjct: 831  LGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAP 890

Query: 709  QYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMM 768
                  P+ +  PA   P  +P P    +P       GAK  +P Q    H  +S  P  
Sbjct: 891  IPSHTAPRPNPTPA-PPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQ----HHFSSGIPAG 945

Query: 769  QAAAAAGP---PLVAATPYSSYIPYNPQQ---------FPGQ-PAMMQPMAHYPSQPVFA 815
              A   GP   P     P  ++ P  PQQ         FP Q P ++ P + YP  P   
Sbjct: 946  FPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPG 1005

Query: 816  PMLQSNPRMLTS-----GSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHA 870
             + Q  P + T         P    S + P +PS   P P           PH      A
Sbjct: 1006 VLGQPPPPLHTQLYPGPAQDPLPAHSGALP-FPSPGPPQP-----------PHPPL---A 1050

Query: 871  HQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGP 930
            + P P+T P G Q     AAP  ++         G     Q+   P  +    PS  PGP
Sbjct: 1051 YGPAPSTRPMGPQ-----AAPLTIR---------GPSSAGQSTPSPHLVPSPAPSPGPGP 1096

Query: 931  SAQSPQSSFPQP 942
                P ++ P P
Sbjct: 1097 VPPRPPAAEPPP 1108



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 48/164 (29%), Positives = 60/164 (36%), Gaps = 29/164 (17%)

Query: 888  HAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPP---GPSAQSPQSSFPQ--P 942
            H  PSP     G  PH  SG        PG  +G    + P   GP A  P +  P   P
Sbjct: 770  HFPPSPFPSSTGPGPHYLSGP-----LPPGTYSGPTQLIQPRAPGPHAM-PVAPGPALYP 823

Query: 943  AAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQ 1002
            A  Y      +P        V+  +V  G     PP  G P  P      PPQ  G    
Sbjct: 824  APAYTPELGLVPRSSPQHGVVSSPYVGVG---PAPPVAGLPSAP------PPQFSGPELA 874

Query: 1003 GAVP---------QSGVPALSASTPSPYPYIGHPQAPLPPPGEL 1037
             AV          Q+ +P+ +A  P+P P    P  P+PPP  L
Sbjct: 875  MAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPL 918



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 113/459 (24%), Positives = 150/459 (32%), Gaps = 118/459 (25%)

Query: 374  PGLSSLPPRGPHHLDNSSP--------------GPGSEARGINGGPSRMSPKAQRPLRGA 419
            P  SS  P GPH+L    P               PG  A  +  GP+     A  P  G 
Sbjct: 775  PFPSSTGP-GPHYLSGPLPPGTYSGPTQLIQPRAPGPHAMPVAPGPALYPAPAYTPELGL 833

Query: 420  KTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE--PPIGSAVPTSSAS 477
               SSP +       V   P VG            PAP  A  P   PP  S    + A 
Sbjct: 834  VPRSSPQH------GVVSSPYVG----------VGPAPPVAGLPSAPPPQFSGPELAMAV 877

Query: 478  IPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQ 537
             P T++V        S  +P+ +  P          P + L          K P     Q
Sbjct: 878  RPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQP--IPAQ 935

Query: 538  KRFQLE-----ELRKFGAQFKLQPSSSPENSLDPFPPR--ILKEEPKGKEKEVDGLLTSE 590
              F           + G Q +  P   P  +  P PP+  +  + P     +  GLL   
Sbjct: 936  HHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLL--- 992

Query: 591  PMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPV 650
            P  SP               P AP  G  G  QPPPP  +Q       L  G  +D  P 
Sbjct: 993  PPQSPY--------------PYAPQPGVLG--QPPPPLHTQ-------LYPGPAQDPLPA 1029

Query: 651  AEQVKKSTLNPNAKEFNPTKPLLSVNKSTST-PTSP--GPRTHSTPSIPVLTAGQSGLYS 707
                      P+     P  P L+   + ST P  P   P T   PS    +AGQS    
Sbjct: 1030 HSGALPF---PSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPS----SAGQS---- 1078

Query: 708  PQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPM 767
                             +P + P P  +  P          G +PP+      PA+ PP 
Sbjct: 1079 ---------------TPSPHLVPSPAPSPGP----------GPVPPR-----PPAAEPPP 1108

Query: 768  MQAAAAAGPPLVAATPYSSYIPYNPQQFP--GQPAMMQP 804
                 AA   L++++P S    +   Q P  GQP ++QP
Sbjct: 1109 CLRRGAAAADLLSSSPESQ---HGGTQSPGGGQP-LLQP 1143



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 30/86 (34%), Positives = 37/86 (43%), Gaps = 18/86 (20%)

Query: 26   RPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQ 85
            RPPGG   P   LPGP    A PPG P A+ P   P+ ++          + +P P  PQ
Sbjct: 1508 RPPGGLESPVASLPGP----AEPPGLPPASLPESTPIPSS------SPPPLSSPLPEAPQ 1557

Query: 86   QHQERPGAAAIGSARGQSTGKGPPQS 111
              +E P   A  S        GPP S
Sbjct: 1558 PKEEPPVPEAPSS--------GPPSS 1575



 Score = 38.1 bits (87), Expect = 0.044
 Identities = 117/500 (23%), Positives = 163/500 (32%), Gaps = 91/500 (18%)

Query: 405  PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464
            P   +PK   P R         + P    S+PP    G    PR              P+
Sbjct: 718  PRPTAPKPLLPRREESEAVEAGDPPEELRSLPPDMVAG----PR-------------LPD 760

Query: 465  PPIGSAVPTSSASIPVTSSVSDPGVGSIS-PASPKISLAPTDVKELSTKEPGRTLEPQEL 523
              +GSA P      P  SS + PG   +S P  P     PT +  +  + PG    P   
Sbjct: 761  TFLGSATPLHFPPSPFPSS-TGPGPHYLSGPLPPGTYSGPTQL--IQPRAPGPHAMP--- 814

Query: 524  ARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEV 583
                   PG         L     +  +  L P SSP++ +   P         G    V
Sbjct: 815  -----VAPGP-------ALYPAPAYTPELGLVPRSSPQHGVVSSP-----YVGVGPAPPV 857

Query: 584  DGLLTSEP-------MGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPC----PSQT 632
             GL ++ P       +   V   T +V   +   P   +        PPPPC    P Q 
Sbjct: 858  AGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQP 917

Query: 633  GSPPVGLIKGEDKDEGPVAEQVKKSTLNP---NAKEFNP-----TKPLLSVNKSTSTPTS 684
               P     G  +   P+  Q   S+  P    A    P      +P  S       P  
Sbjct: 918  LPTPYTYPAGAKQ---PIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQ 974

Query: 685  PGPRTHSTPSIPVLTAGQS-GLYSPQY-ISYIPQ---IHMGPAVQAPQMYPYPVSNSVPG 739
            P P  H     P L   Q+ GL  PQ    Y PQ   +   P     Q+YP P  + +P 
Sbjct: 975  PLPLQH-----PHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPA 1029

Query: 740  QQG--KYRGAKGSLPPQRSDQHQPA-SAPPMMQAAA---AAGPPLVAATPYSSYIPYNPQ 793
              G   +       PP     + PA S  PM   AA     GP     +  S ++  +P 
Sbjct: 1030 HSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPA 1089

Query: 794  QFPG------QPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHP----QAIVSSSTPQYP 843
              PG      +P   +P          A +L S+P     G+      Q ++  +  +  
Sbjct: 1090 PSPGPGPVPPRPPAAEPPPCLRRGAAAADLLSSSPESQHGGTQSPGGGQPLLQPT--KVD 1147

Query: 844  SAEQPTPQALYATVHQSYPH 863
            +AE   PQAL       Y H
Sbjct: 1148 AAEGRRPQALRLIERDPYEH 1167



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 38/132 (28%), Positives = 43/132 (32%), Gaps = 28/132 (21%)

Query: 4    PQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGG-----LPGPLATSAAPPGPPAAASPC 58
            P P   P+  +QP P Q   +   P G   P  G      P P  + A  P PP    P 
Sbjct: 919  PTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPL 978

Query: 59   LGPVAAAGSGLRRGAEGILAP--------------QPPPPQQHQERPGAA----AIGSAR 100
              P           A G+L P              QPPPP   Q  PG A       S  
Sbjct: 979  QHPHLFPPQ-----APGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGA 1033

Query: 101  GQSTGKGPPQSP 112
                  GPPQ P
Sbjct: 1034 LPFPSPGPPQPP 1045



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 38/121 (31%), Positives = 44/121 (36%), Gaps = 19/121 (15%)

Query: 3    KPQPLQQPSQ------PQQPPPTQ-------QAVARRPPGGTSP-PNGGLPGPLATSAAP 48
            +P P   PSQ      PQQP P Q       QA    PP   SP P    PG L     P
Sbjct: 956  QPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPP--QSPYPYAPQPGVLGQPPPP 1013

Query: 49   PGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPP-PPQQHQERPGAAAIGSARGQSTGKG 107
                    P   P+ A    L   + G   PQPP PP  +   P    +G      T +G
Sbjct: 1014 LHTQLYPGPAQDPLPAHSGALPFPSPG--PPQPPHPPLAYGPAPSTRPMGPQAAPLTIRG 1071

Query: 108  P 108
            P
Sbjct: 1072 P 1072



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 51/201 (25%), Positives = 73/201 (36%), Gaps = 29/201 (14%)

Query: 351  PLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSP 410
            PL  ++  GP      + S G  P  S  PP+ PH      P P +   G    P  +  
Sbjct: 1013 PLHTQLYPGPAQDPLPAHS-GALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTI-- 1069

Query: 411  KAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSA 470
              + P    ++  SP   PS   S  P P      PPR P +           EPP    
Sbjct: 1070 --RGPSSAGQSTPSPHLVPSPAPSPGPGPV-----PPRPPAA-----------EPPPCLR 1111

Query: 471  VPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKV 530
               ++A +  +S  S  G G+ SP   +  L PT V     + P       +  R+  + 
Sbjct: 1112 RGAAAADLLSSSPESQHG-GTQSPGGGQPLLQPTKVDAAEGRRP-------QALRLIERD 1163

Query: 531  PGLQNEQKRFQLEELRKFGAQ 551
            P    E+ R   +EL  F  Q
Sbjct: 1164 PYEHPERLRQLQQELEAFRGQ 1184



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 28/94 (29%), Positives = 30/94 (31%), Gaps = 10/94 (10%)

Query: 4    PQPLQQPSQPQQPPPTQ-QAVARRPPG---------GTSPPNGGLPGPLATSAAPPGPPA 53
            P P   P QP  PP     A + RP G         G S      P P    +  P P  
Sbjct: 1035 PFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGP 1094

Query: 54   AASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQH 87
               P   P A     LRRGA         P  QH
Sbjct: 1095 GPVPPRPPAAEPPPCLRRGAAAADLLSSSPESQH 1128



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 37/148 (25%), Positives = 57/148 (38%), Gaps = 21/148 (14%)

Query: 421  TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAP--APISASCPEPPIGSAVPTSSASI 478
            T++  S RP G    P     G   PP  P ++ P   PI +S P PP+ S +P +    
Sbjct: 1501 TIAKLSIRPPGGLESPVASLPGPAEPPGLPPASLPESTPIPSSSP-PPLSSPLPEAPQ-- 1557

Query: 479  PVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQK 538
                              P +  AP+     S+ E   +L P+  + +   + G Q   K
Sbjct: 1558 --------------PKEEPPVPEAPSSGPPSSSLELLASLTPEAFS-LDSSLRGKQRMSK 1602

Query: 539  RFQLEELRKFGAQFKLQPSSSPENSLDP 566
               L+     G +   +PS  P + LDP
Sbjct: 1603 HNFLQAHNGQGLR-ATRPSDDPLSLLDP 1629



 Score = 31.2 bits (69), Expect = 5.3
 Identities = 26/84 (30%), Positives = 34/84 (40%), Gaps = 4/84 (4%)

Query: 560  PENSLDPFPPRILKEEPKGKEKEVDGLL-TSEPMGSPVSSKTESVSDKEDKPPLAPSGGT 618
            P +S+     ++    P G E  V  L   +EP G P +S  ES       PP   S   
Sbjct: 1494 PISSIQATIAKLSIRPPGGLESPVASLPGPAEPPGLPPASLPESTPIPSSSPPPLSSPLP 1553

Query: 619  EGP---EQPPPPCPSQTGSPPVGL 639
            E P   E+PP P    +G P   L
Sbjct: 1554 EAPQPKEEPPVPEAPSSGPPSSSL 1577



 Score = 30.8 bits (68), Expect = 7.0
 Identities = 30/111 (27%), Positives = 36/111 (32%), Gaps = 5/111 (4%)

Query: 7   LQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAG 66
           +Q P      P      A  PP    PP   LP P    A    P  A       + A  
Sbjct: 887 IQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGF 946

Query: 67  SGLRRGAEGILAPQPPPPQQHQERPGAAAIGSAR-----GQSTGKGPPQSP 112
              R G +    PQP P Q    +P    +          Q+ G  PPQSP
Sbjct: 947 PAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSP 997



 Score = 30.4 bits (67), Expect = 9.1
 Identities = 26/88 (29%), Positives = 33/88 (37%), Gaps = 20/88 (22%)

Query: 927  PPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPP 986
            PPG   +SP +S P PA    +    LP               T I ++ PP   +P P 
Sbjct: 1509 PPG-GLESPVASLPGPAEPPGLPPASLPES-------------TPIPSSSPPPLSSPLP- 1553

Query: 987  QVMLLHPPQSHGGPPQGAVPQSGVPALS 1014
                   PQ    PP    P SG P+ S
Sbjct: 1554 -----EAPQPKEEPPVPEAPSSGPPSSS 1576


>gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
            sapiens]
          Length = 1858

 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 110/438 (25%), Positives = 151/438 (34%), Gaps = 72/438 (16%)

Query: 651  AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQY 710
            +EQ+ +   +   K   P  P L     +STP +P    + +P  P    G    Y P +
Sbjct: 1425 SEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSP--YRPHH 1482

Query: 711  ISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQA 770
             S  PQ+  G   + PQ   YP + ++P      +   G+L  Q       A+     Q 
Sbjct: 1483 -SQSPQV--GTPQREPQRNFYPAAQNLPANT--QQATSGTLFTQTPSGQSSATYSQFNQQ 1537

Query: 771  A--AAAGPPLVAATPYSSYIP----------YNP----------------QQFPGQPAMM 802
            +  + A PP     P SSY            YN                 Q  PG  +  
Sbjct: 1538 SLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQ 1597

Query: 803  QPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYP 862
                H+ +   F P    NP +     H Q   +   P  P    P P  +      S+ 
Sbjct: 1598 TVPGHHVTPGHFLP--SQNPTI-----HHQTAAAVVPPPPPPPPAPGPHLVQQP--NSHQ 1648

Query: 863  HHATQLHAHQPQPATTPTGSQPQSQHAA---------PSPVQHQAGQAPHLGSGQPQQNL 913
             H+   H   P  A TP GS   SQ A          P P  H     PH  +G      
Sbjct: 1649 QHSVA-HVVGPVHAVTP-GSHIHSQTAGHHLPPPPPPPGPAPHHH-PPPHPSTGLQGLQA 1705

Query: 914  YHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHH--QQLPHGFTNMAHVTQAHVQTG 971
             H   +   PP  PP P   S  +S     +  A+HH   Q P  F + AH T     + 
Sbjct: 1706 QHQHVVNSAPPP-PPPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQ 1764

Query: 972  ITAAPPPHPGAPHPPQVMLLHPPQSHGGP---PQGAVPQSGVPALSASTPSPYP------ 1022
             T      PG  H P     H P    GP   PQG    + +P  +AS   P+P      
Sbjct: 1765 ATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQG---PNSIPTPTASGFCPHPGSVALP 1821

Query: 1023 -YIGHPQAPLPPPGELKI 1039
              +  PQ   P PG++ I
Sbjct: 1822 HGVQGPQQASPVPGQIPI 1839



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 136/590 (23%), Positives = 205/590 (34%), Gaps = 109/590 (18%)

Query: 421  TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASC---PEPPIGSAVPTSSAS 477
            T   PS   S  T   PP    +M  P SP S  PA         P+P   S V  S A 
Sbjct: 1335 TNECPSPDTSQNTCKSPP----KMSKPGSPGSVIPAQAHGKIFTKPDPQWDSTVSASEAE 1390

Query: 478  --IPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQN 535
              + + + +    + + + A  K     T V+  S+++  + L            P L+N
Sbjct: 1391 NGVHLKTELQQKQLSNNNQALSKNHPPQTHVRN-SSEQLSQKLPSVPTKLHCPPSPHLEN 1449

Query: 536  EQKRFQLEE------------LRKFGAQFKLQPSSSPENSLDPFPPR-----ILKEEPKG 578
              K                   ++ G+ ++   S SP+       P+       +  P  
Sbjct: 1450 PPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPAN 1509

Query: 579  KEKEVDG-LLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQT---GS 634
             ++   G L T  P G   SS T S  +++       S  +  P  PPPP PS +     
Sbjct: 1510 TQQATSGTLFTQTPSGQ--SSATYSQFNQQ-------SLNSTAPPPPPPPPPSSSYYQNQ 1560

Query: 635  PPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPS 694
             P    +  ++ +G +++Q    T  PN           ++  +TS  T PG   H TP 
Sbjct: 1561 QPSANFQNYNQLKGSLSQQT-VFTSGPNQ----------ALPGTTSQQTVPG--HHVTPG 1607

Query: 695  IPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVS---NSVPGQQGKYRGAK--G 749
               L +    ++     + +P     P    P +   P S   +SV    G         
Sbjct: 1608 -HFLPSQNPTIHHQTAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGS 1666

Query: 750  SLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYP 809
             +  Q +  H P   PP        GP      P+    P+      G  A  Q + +  
Sbjct: 1667 HIHSQTAGHHLPPPPPP-------PGP-----APHHHPPPHPSTGLQGLQAQHQHVVNSA 1714

Query: 810  SQPVFAPMLQSNPRMLTSGSHPQAIVS------SSTPQYPSAEQPT--PQALYATVHQSY 861
              P   P   S   +L SG H  +  +         P +PS+  PT  P    AT H + 
Sbjct: 1715 PPPPPPPPPSS---VLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHHTTL 1771

Query: 862  ----PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPG 917
                 H  +    H P P T P   QPQ  ++ P+P    +G  PH GS           
Sbjct: 1772 GPGPQHQPSGTGPHCPLPVTGP-HLQPQGPNSIPTPT--ASGFCPHPGS----------- 1817

Query: 918  ALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAH 967
                   +LP G   Q PQ + P P  +  IH  Q+P  F N  H +  H
Sbjct: 1818 ------VALPHG--VQGPQQASPVPGQI-PIHRAQVPPTFQNNYHGSGWH 1858



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 37/151 (24%), Positives = 54/151 (35%), Gaps = 17/151 (11%)

Query: 340  PSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEAR 399
            PS     G +    Q +   P  G     S    P +   P +  HH   ++ GPG + +
Sbjct: 1723 PSSVLASGHHTTSAQALHHPPHQGPPLFPS-SAHPTVPPYPSQATHH---TTLGPGPQHQ 1778

Query: 400  GINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPIS 459
                 PS   P    P+ G      P  +P G  S+P P A G  + P     A P  + 
Sbjct: 1779 -----PSGTGPHCPLPVTG------PHLQPQGPNSIPTPTASG--FCPHPGSVALPHGVQ 1825

Query: 460  ASCPEPPIGSAVPTSSASIPVTSSVSDPGVG 490
                  P+   +P   A +P T   +  G G
Sbjct: 1826 GPQQASPVPGQIPIHRAQVPPTFQNNYHGSG 1856


>gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
            sapiens]
          Length = 1858

 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 110/438 (25%), Positives = 151/438 (34%), Gaps = 72/438 (16%)

Query: 651  AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQY 710
            +EQ+ +   +   K   P  P L     +STP +P    + +P  P    G    Y P +
Sbjct: 1425 SEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSP--YRPHH 1482

Query: 711  ISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQA 770
             S  PQ+  G   + PQ   YP + ++P      +   G+L  Q       A+     Q 
Sbjct: 1483 -SQSPQV--GTPQREPQRNFYPAAQNLPANT--QQATSGTLFTQTPSGQSSATYSQFNQQ 1537

Query: 771  A--AAAGPPLVAATPYSSYIP----------YNP----------------QQFPGQPAMM 802
            +  + A PP     P SSY            YN                 Q  PG  +  
Sbjct: 1538 SLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQ 1597

Query: 803  QPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYP 862
                H+ +   F P    NP +     H Q   +   P  P    P P  +      S+ 
Sbjct: 1598 TVPGHHVTPGHFLP--SQNPTI-----HHQTAAAVVPPPPPPPPAPGPHLVQQP--NSHQ 1648

Query: 863  HHATQLHAHQPQPATTPTGSQPQSQHAA---------PSPVQHQAGQAPHLGSGQPQQNL 913
             H+   H   P  A TP GS   SQ A          P P  H     PH  +G      
Sbjct: 1649 QHSVA-HVVGPVHAVTP-GSHIHSQTAGHHLPPPPPPPGPAPHHH-PPPHPSTGLQGLQA 1705

Query: 914  YHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHH--QQLPHGFTNMAHVTQAHVQTG 971
             H   +   PP  PP P   S  +S     +  A+HH   Q P  F + AH T     + 
Sbjct: 1706 QHQHVVNSAPPP-PPPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQ 1764

Query: 972  ITAAPPPHPGAPHPPQVMLLHPPQSHGGP---PQGAVPQSGVPALSASTPSPYP------ 1022
             T      PG  H P     H P    GP   PQG    + +P  +AS   P+P      
Sbjct: 1765 ATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQG---PNSIPTPTASGFCPHPGSVALP 1821

Query: 1023 -YIGHPQAPLPPPGELKI 1039
              +  PQ   P PG++ I
Sbjct: 1822 HGVQGPQQASPVPGQIPI 1839



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 136/590 (23%), Positives = 205/590 (34%), Gaps = 109/590 (18%)

Query: 421  TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASC---PEPPIGSAVPTSSAS 477
            T   PS   S  T   PP    +M  P SP S  PA         P+P   S V  S A 
Sbjct: 1335 TNECPSPDTSQNTCKSPP----KMSKPGSPGSVIPAQAHGKIFTKPDPQWDSTVSASEAE 1390

Query: 478  --IPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQN 535
              + + + +    + + + A  K     T V+  S+++  + L            P L+N
Sbjct: 1391 NGVHLKTELQQKQLSNNNQALSKNHPPQTHVRN-SSEQLSQKLPSVPTKLHCPPSPHLEN 1449

Query: 536  EQKRFQLEE------------LRKFGAQFKLQPSSSPENSLDPFPPR-----ILKEEPKG 578
              K                   ++ G+ ++   S SP+       P+       +  P  
Sbjct: 1450 PPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPAN 1509

Query: 579  KEKEVDG-LLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQT---GS 634
             ++   G L T  P G   SS T S  +++       S  +  P  PPPP PS +     
Sbjct: 1510 TQQATSGTLFTQTPSGQ--SSATYSQFNQQ-------SLNSTAPPPPPPPPPSSSYYQNQ 1560

Query: 635  PPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPS 694
             P    +  ++ +G +++Q    T  PN           ++  +TS  T PG   H TP 
Sbjct: 1561 QPSANFQNYNQLKGSLSQQT-VFTSGPNQ----------ALPGTTSQQTVPG--HHVTPG 1607

Query: 695  IPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVS---NSVPGQQGKYRGAK--G 749
               L +    ++     + +P     P    P +   P S   +SV    G         
Sbjct: 1608 -HFLPSQNPTIHHQTAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGS 1666

Query: 750  SLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYP 809
             +  Q +  H P   PP        GP      P+    P+      G  A  Q + +  
Sbjct: 1667 HIHSQTAGHHLPPPPPP-------PGP-----APHHHPPPHPSTGLQGLQAQHQHVVNSA 1714

Query: 810  SQPVFAPMLQSNPRMLTSGSHPQAIVS------SSTPQYPSAEQPT--PQALYATVHQSY 861
              P   P   S   +L SG H  +  +         P +PS+  PT  P    AT H + 
Sbjct: 1715 PPPPPPPPPSS---VLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHHTTL 1771

Query: 862  ----PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPG 917
                 H  +    H P P T P   QPQ  ++ P+P    +G  PH GS           
Sbjct: 1772 GPGPQHQPSGTGPHCPLPVTGP-HLQPQGPNSIPTPT--ASGFCPHPGS----------- 1817

Query: 918  ALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAH 967
                   +LP G   Q PQ + P P  +  IH  Q+P  F N  H +  H
Sbjct: 1818 ------VALPHG--VQGPQQASPVPGQI-PIHRAQVPPTFQNNYHGSGWH 1858



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 37/151 (24%), Positives = 54/151 (35%), Gaps = 17/151 (11%)

Query: 340  PSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEAR 399
            PS     G +    Q +   P  G     S    P +   P +  HH   ++ GPG + +
Sbjct: 1723 PSSVLASGHHTTSAQALHHPPHQGPPLFPS-SAHPTVPPYPSQATHH---TTLGPGPQHQ 1778

Query: 400  GINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPIS 459
                 PS   P    P+ G      P  +P G  S+P P A G  + P     A P  + 
Sbjct: 1779 -----PSGTGPHCPLPVTG------PHLQPQGPNSIPTPTASG--FCPHPGSVALPHGVQ 1825

Query: 460  ASCPEPPIGSAVPTSSASIPVTSSVSDPGVG 490
                  P+   +P   A +P T   +  G G
Sbjct: 1826 GPQQASPVPGQIPIHRAQVPPTFQNNYHGSG 1856


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 114/433 (26%), Positives = 150/433 (34%), Gaps = 58/433 (13%)

Query: 621  PEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTS 680
            P  PPP  P  TG        G+    G     + + T  P      P  PL  V     
Sbjct: 708  PVLPPPSTPMPTGP-------GQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPV----- 755

Query: 681  TPTSPGPRTHSTPSIPVLTAGQSGLYSPQYIS--YIPQIHMGPAVQAP-QMYPYPVSNSV 737
                        P +P   A  S + +P  +    +PQ  + P  Q P QM P PV   +
Sbjct: 756  -----------PPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPI 804

Query: 738  PGQQGKYRGAKGSLPPQRSDQHQ---PASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQ 794
                G        LPP   D      P   PP   + A   P L A  P +S  P  P Q
Sbjct: 805  TPLAGI-----DGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPAS--PALPLQ 857

Query: 795  F------PGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVS-SSTPQYPSAEQ 847
                   PG P  M      P+ P   P+L   P  + + S   A+      P YP+A  
Sbjct: 858  AVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAA-- 915

Query: 848  PTPQALYATVHQSYPHHATQ-LHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGS 906
              PQ     V  S PHH  Q + A  PQPA  P  + P      P P        P   +
Sbjct: 916  -FPQMAPTDVPPS-PHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPT 973

Query: 907  GQPQQNLYHPGALTGTPPSLPPGPS----AQSPQSSFPQPAAVYAIHHQQLPHGFTNMAH 962
             +P Q +  P  +    P LPP P+     +  Q   P+ AA  A    Q+  G     +
Sbjct: 974  -RPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHP-APY 1031

Query: 963  VTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYP 1022
                  Q      PP    +P  P+V+L   P+     PQ     + V A   S P+   
Sbjct: 1032 AVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPEL---LPQFPSSLATVSASVQSVPTQTA 1088

Query: 1023 YIGHPQAPLPPPG 1035
             +  P  P P PG
Sbjct: 1089 TLLPPANP-PLPG 1100



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 75/267 (28%), Positives = 88/267 (32%), Gaps = 42/267 (15%)

Query: 770  AAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGS 829
            A AA  P     +P  S  P  PQ  P   A  QP A  P  PV +    + P  L    
Sbjct: 641  ADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTA-APGLPVGSVPAPACPPSLQQHF 699

Query: 830  HPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHA 889
               A+  +     PS   PT     A   Q            QP P   PT   P  Q  
Sbjct: 700  PDPAMSFAPVLPPPSTPMPTGPGQPAPPGQ------------QPPPLAQPT---PLPQVL 744

Query: 890  APSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIH 949
            AP PV       PHL           P +  G P  L P    Q+P     QP A     
Sbjct: 745  APQPVVPLQPVPPHL------PPYLAPASQVGAPAQLKPLQMPQAPL----QPLA----- 789

Query: 950  HQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSG 1009
              Q+P     +  V       GI   PP  P  P         PP     PPQ   P   
Sbjct: 790  --QVPPQMPPIPVVPPITPLAGIDGLPPALPDLP-----TATVPPVP---PPQYFSPAVI 839

Query: 1010 VPALSASTPSPYPYIGHPQAPLP-PPG 1035
            +P+L+A  P   P +      LP PPG
Sbjct: 840  LPSLAAPLPPASPALPLQAVKLPHPPG 866



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 53/179 (29%), Positives = 70/179 (39%), Gaps = 21/179 (11%)

Query: 352 LPQRVREGPRG----GVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSR 407
           +P  + E  RG    G+    ++  RPG      R     D   P PG EA    G P  
Sbjct: 10  VPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEP-PGLEAAEAPG-PQP 67

Query: 408 MSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA-VGRMYPPRSPKSAAPAPISASCPEP- 465
             P  +R L   KT    + R  G  + P P A V +   P +P  A P P+    P P 
Sbjct: 68  PQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGPD 127

Query: 466 PIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTL--EPQE 522
           PI +AV T+ A          P  G    A+  +        E +  EPGRT   EP+E
Sbjct: 128 PIAAAVETAPA----------PDGGPREEAAATVRKEDEGAAE-AKPEPGRTRRDEPEE 175



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 78/303 (25%), Positives = 108/303 (35%), Gaps = 46/303 (15%)

Query: 736  SVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSY-IPYNPQQ 794
            S PG    +    G    + S Q Q A+AP   Q     G       P + +  P  P+ 
Sbjct: 1271 SDPGTSPPHLSTCGLGTGEESRQSQ-ANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPES 1329

Query: 795  FPGQP-AMMQPMAHYPSQPVFAPMLQSN--PRMLTSGSHPQAIVSSSTPQYPSAEQPTPQ 851
             P  P + + P A   S P +   L S   P  L S    Q ++S + P  P    P P 
Sbjct: 1330 SPPLPLSSLPPEASQDSAP-YKDQLSSKEQPSFLAS----QQLLSQAGPSNPPGAPPAPL 1384

Query: 852  ALYATVHQSYPHH-ATQLHAHQPQPAT----------TPTG-------SQPQSQ-HAAPS 892
            A  +    + P   A    +  P+PA+          TP G       SQP ++ H AP 
Sbjct: 1385 APSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPL 1444

Query: 893  PVQHQA-GQAPHLGSGQPQQNLYHPGALTGTPPSLP-PGPSAQSPQSSFPQPAAVYAIHH 950
             VQ    G AP   + +              PP  P P P + +PQ +  QPA +     
Sbjct: 1445 AVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPL----- 1499

Query: 951  QQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGV 1010
              LP      A V    + T    +PP  P  P  P   L       G PP+     S +
Sbjct: 1500 --LP------AAVGAVSLATSQLPSPPLGPTVPPQPPSAL--ESDGEGPPPRVGFVDSTI 1549

Query: 1011 PAL 1013
             +L
Sbjct: 1550 KSL 1552



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 179/825 (21%), Positives = 273/825 (33%), Gaps = 171/825 (20%)

Query: 1    MLKPQPL--QQPSQPQQPPPTQQAVARRPPGGTSPPNG---GLPGPLATSAAP-----PG 50
            ML PQP+   QP+ P +P P Q  +  +     +P +    G P P A   A      P 
Sbjct: 985  MLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPV 1044

Query: 51   PPAA------------ASPCLGP--------VAAAGSGLRRGAEGILAPQPPPPQQHQER 90
            PPAA            A+P L P        V+A+   +      +L P  PP       
Sbjct: 1045 PPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPP------L 1098

Query: 91   PGAAAIGSA------------RGQSTGKGPPQSPVFEGVYNNSRMLHFLTAVVGSTCDVK 138
            PG   I S               Q++   PP  P     Y  S +       +  +C+  
Sbjct: 1099 PGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGGSDVTS--GKELSDSCE-- 1154

Query: 139  VKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRRE-----DIVDTMV---FKPSDV 190
               G    G  +  +++         R   E A  PR       +  D MV    +  + 
Sbjct: 1155 ---GAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDKMVECQLETHNH 1211

Query: 191  MLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDDYDLESDMSNG 250
             +V F+  D +    D+     +  +  +  E +  + Q  +  D   D    ++D   G
Sbjct: 1212 KMVTFK-FDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDMLSEDTDADRG 1270

Query: 251  WDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLAREI-----ES 305
             DP      +    G+ T  +S  S    P+ + N     +R      +A        ES
Sbjct: 1271 SDPGTSPP-HLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPES 1329

Query: 306  SPQYRLRIAMENDDGRTEEEKHSAVQR-QGSGRESPS-LASREGKYIPLPQRVREGPRGG 363
            SP   L           E  + SA  + Q S +E PS LAS++      P      P   
Sbjct: 1330 SPPLPLSSLPP------EASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAP 1383

Query: 364  VRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGP------------------ 405
            +  SS     P +++LP  G     ++ P P S      GGP                  
Sbjct: 1384 LAPSS-----PPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAE 1438

Query: 406  SRMSPKAQRPLRG--AKTLSSPSNRPSGETSVP----PPPAVGRMYPPRSPKSAAPAPI- 458
            +  +P A +PL    A    +P    + + S P    PPPA     P  SP S  P P  
Sbjct: 1439 THEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPA-----PEPSPHSGTPQPAL 1493

Query: 459  -----------------SASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISL 501
                             ++  P PP+G  VP    S   +     P         P++  
Sbjct: 1494 GQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPP---------PRVGF 1544

Query: 502  APTDVKELSTKEPGRTLEPQELARIAGKVPGLQNE--QKRFQLEELRKFGAQFKLQPSSS 559
              + +K L  K   RTL  QE    +    G   E   + F LE LR  G Q + +    
Sbjct: 1545 VDSTIKSLDEKL--RTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLR--GDQPRSEVCGG 1600

Query: 560  PENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTE 619
             + +L P P   +    +  +  V+    +   G+ +   T S    E  P        +
Sbjct: 1601 -DLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRD 1659

Query: 620  GPE--QPPPPCPSQTGSPPV----GLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLL 673
            G +        PS     P       ++  D+D G   E    S+  P      P   + 
Sbjct: 1660 GRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGE----SSAEP------PPSDMG 1709

Query: 674  SVNKSTSTPTSPGPRTHSTP---------SIPVLTAGQSGLYSPQ 709
            +V    S P + G R   +P         S P  T G+  + S Q
Sbjct: 1710 TVGGQASHPQTLGARALGSPRKRPEQQDVSSPAKTVGRFSVVSTQ 1754



 Score = 40.0 bits (92), Expect = 0.011
 Identities = 66/249 (26%), Positives = 93/249 (37%), Gaps = 47/249 (18%)

Query: 804  PMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSST--PQYPSAEQPTPQALYATVHQSY 861
            P+A +P+    AP  +S+P +  S   P+A   S+    Q  S EQP+  A    + Q+ 
Sbjct: 1317 PVAEHPAPE--AP--ESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAG 1372

Query: 862  PHHATQLHAHQPQPATTPTGSQPQSQHAA-----PSPVQHQAGQAPHLGSGQPQQNLYHP 916
            P +          P++ P  + PQ   A      P P    A QA   G G PQ      
Sbjct: 1373 PSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAG--GPGTPQ------ 1424

Query: 917  GALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAP 976
            G  +    S P   + ++P +   QP  V              +A  T A        A 
Sbjct: 1425 GLTSELETSQPLAETHEAPLAV--QPLVV-------------GLAPCTPAPEAASTRDAS 1469

Query: 977  PPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQ------SGVPALSASTPS-PYPYIGHPQA 1029
             P    P P        P  H G PQ A+ Q      + V A+S +T   P P +G P  
Sbjct: 1470 APREPLPPPAP-----EPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLG-PTV 1523

Query: 1030 PLPPPGELK 1038
            P  PP  L+
Sbjct: 1524 PPQPPSALE 1532



 Score = 38.1 bits (87), Expect = 0.044
 Identities = 54/208 (25%), Positives = 64/208 (30%), Gaps = 56/208 (26%)

Query: 840  PQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQH--------AAP 891
            P+ P A+Q     L  T+  S    A+       Q +T  + SQ   Q         AAP
Sbjct: 589  PEEPEADQ---HLLPPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAP 645

Query: 892  SPVQ----HQAGQAPHLGSGQPQQNLYH-PGALTGTPPSLPPGPSAQ-SPQSSFPQPAAV 945
            SP Q        + P L    P    Y  P A  G P    P P+   S Q  FP PA  
Sbjct: 646  SPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMS 705

Query: 946  YAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAV 1005
            +A                            PPP    P               GP Q A 
Sbjct: 706  FA-------------------------PVLPPPSTPMPT--------------GPGQPAP 726

Query: 1006 PQSGVPALSASTPSPYPYIGHPQAPLPP 1033
            P    P L+  TP P      P  PL P
Sbjct: 727  PGQQPPPLAQPTPLPQVLAPQPVVPLQP 754



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 39/149 (26%), Positives = 60/149 (40%), Gaps = 16/149 (10%)

Query: 376 LSSLPPRGPHHLDNSSP-GPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRP-SGET 433
           L  +PP  P +L  +S  G  ++ + +    + + P AQ P +       P   P +G  
Sbjct: 752 LQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGID 811

Query: 434 SVPP-----PPAVGRMYPPRSPKSAAPAPI--SASCPEPPIGSAVPTSSASIPVTSSVSD 486
            +PP     P A     PP  P+  +PA I  S + P PP   A+P  +  +P       
Sbjct: 812 GLPPALPDLPTATVPPVPP--PQYFSPAVILPSLAAPLPPASPALPLQAVKLP-----HP 864

Query: 487 PGVGSISPASPKISLAPTDVKELSTKEPG 515
           PG     P    +  AP  +  L+   PG
Sbjct: 865 PGAPLAMPCRTIVPNAPATIPLLAVAPPG 893



 Score = 35.0 bits (79), Expect = 0.37
 Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 8/85 (9%)

Query: 12  QPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAA-----SPCLGPVAAAG 66
           +P  P P   A+  +P    +P + G P P+ T    P P AAA     +P  GP   A 
Sbjct: 92  RPAAPAPA--ALVAQPGAPGAPADAG-PEPVGTQEPGPDPIAAAVETAPAPDGGPREEAA 148

Query: 67  SGLRRGAEGILAPQPPPPQQHQERP 91
           + +R+  EG    +P P +  ++ P
Sbjct: 149 ATVRKEDEGAAEAKPEPGRTRRDEP 173



 Score = 33.1 bits (74), Expect = 1.4
 Identities = 60/249 (24%), Positives = 90/249 (36%), Gaps = 50/249 (20%)

Query: 315  MENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGPRGG-VRCSSSRGGR 373
            ME     +   + S     G  R+   +AS       +PQ V    R   V  +   GG 
Sbjct: 1636 MEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGE 1695

Query: 374  PGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGET 433
             G SS  P            P S+   + G  S           GA+ L SP  RP  + 
Sbjct: 1696 AGESSAEP------------PPSDMGTVGGQASHPQTL------GARALGSPRKRPEQQD 1737

Query: 434  SVPPPPAVGR-----------MYPPRSPKSAAPAPI----SASCPEPPIGSAVPTSSASI 478
               P   VGR           +  P S + +AP  +    + S P+  +      +++SI
Sbjct: 1738 VSSPAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSI 1797

Query: 479  ------PVTSSVSDPGVGSISPASPKISL------APTDVKELST--KEPGR--TLEPQE 522
                  PV+S   D G  +  P   + SL      A   VK+ +   + P R  +L P+ 
Sbjct: 1798 EVGVGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPET 1857

Query: 523  LARIAGKVP 531
             +R+  KVP
Sbjct: 1858 PSRVGMKVP 1866



 Score = 32.7 bits (73), Expect = 1.8
 Identities = 31/116 (26%), Positives = 45/116 (38%), Gaps = 13/116 (11%)

Query: 910  QQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQ---- 965
            QQN+ H G        +   P+ ++P+SS P P +       Q    + +     +    
Sbjct: 1302 QQNVLHTGKRWFIICPVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSF 1361

Query: 966  -AHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
             A  Q    A P   PGAP  P       P S   PP  A+PQ G    +++ P P
Sbjct: 1362 LASQQLLSQAGPSNPPGAPPAPLA-----PSS---PPVTALPQDGAAPATSTMPEP 1409



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 50/200 (25%), Positives = 71/200 (35%), Gaps = 31/200 (15%)

Query: 622  EQPPPPCPSQTGSPPVGLIKGE-DKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTS 680
            E P P  P  +   P+  +  E  +D  P  +Q+           F  ++ LLS    ++
Sbjct: 1320 EHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSK----EQPSFLASQQLLSQAGPSN 1375

Query: 681  TPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQA-----PQMYPYPVSN 735
             P +P P   +  S PV    Q G  +    S +P+   G A QA     PQ     +  
Sbjct: 1376 PPGAP-PAPLAPSSPPVTALPQDG--AAPATSTMPEPASGTASQAGGPGTPQGLTSELET 1432

Query: 736  SVP---------GQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSS 786
            S P           Q    G     P   +   + ASAP          PP    +P+S 
Sbjct: 1433 SQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAP-----REPLPPPAPEPSPHSG 1487

Query: 787  YIPYNPQQFPGQPAMMQPMA 806
                 PQ   GQPA + P A
Sbjct: 1488 ----TPQPALGQPAPLLPAA 1503



 Score = 31.6 bits (70), Expect = 4.1
 Identities = 20/56 (35%), Positives = 20/56 (35%)

Query: 2   LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASP 57
           L PQP   P     P PT       PP  T PP   LP        P  PP  A P
Sbjct: 944 LPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALP 999



 Score = 30.8 bits (68), Expect = 7.0
 Identities = 29/103 (28%), Positives = 41/103 (39%), Gaps = 10/103 (9%)

Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464
           P   SP    P   A    +    P     +P PP      P R+    APA I      
Sbjct: 831 PQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATI------ 884

Query: 465 PPIGSAVPTSSASIPVTSSVSD-PGVGSISPASPKISLAPTDV 506
            P+ +  P   A++ + S+V+  PG      A P+  +APTDV
Sbjct: 885 -PLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQ--MAPTDV 924



 Score = 30.4 bits (67), Expect = 9.1
 Identities = 23/74 (31%), Positives = 26/74 (35%), Gaps = 9/74 (12%)

Query: 13  PQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRG 72
           P  P  T Q +   PP    PP   LP        PP P     P L P         R 
Sbjct: 925 PPSPHHTVQNMRATPPQPALPPQPTLP---PQPVLPPQPTLPPQPVLPPQPT------RP 975

Query: 73  AEGILAPQPPPPQQ 86
            + +L PQP  P Q
Sbjct: 976 PQPVLPPQPMLPPQ 989



 Score = 30.4 bits (67), Expect = 9.1
 Identities = 27/76 (35%), Positives = 29/76 (38%), Gaps = 16/76 (21%)

Query: 10  PSQPQQPP-PTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSG 68
           P QP  PP PT       PP  T PP   LP P  T   PP P     P L P       
Sbjct: 939 PPQPALPPQPTLPPQPVLPPQPTLPPQPVLP-PQPT--RPPQPVLPPQPMLPP------- 988

Query: 69  LRRGAEGILAPQPPPP 84
                + +L PQP  P
Sbjct: 989 -----QPVLPPQPALP 999


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 167/711 (23%), Positives = 236/711 (33%), Gaps = 113/711 (15%)

Query: 305  SSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGPRGGV 364
            SSPQ R R    + D  +  +    +   GS   S   +  + +       V   P+GG 
Sbjct: 400  SSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGG- 458

Query: 365  RCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSS 424
               S RG   G S+           +S      + G   G S    K +RP    +   S
Sbjct: 459  ---SGRGSPSGGSTA---------EASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHS 506

Query: 425  PSNR----PSGETSVPPPPAVGRMYPPRSPK----SAAPAPISASCPEPPIGSAVPTSSA 476
               R    P G   +PP P   R   P+ P+      +    +A CP  P  S VP  S 
Sbjct: 507  LHQRGLAVPDGPLGLPPKPE--RKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLS- 563

Query: 477  SIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNE 536
                      PG     P SP+ +L+P+      +  P  TL P+ LA      PG    
Sbjct: 564  ----------PGGSRRPPRSPERTLSPSSGYSSQSGTP--TLPPKGLAGPPAS-PGKAQP 610

Query: 537  QKRFQLEELRKFGAQFKLQPSSSPENSLDPFP-----PRIL------------------- 572
             K  ++  LR  GA      +S   +S DP P     P+IL                   
Sbjct: 611  PKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPF 670

Query: 573  ---KEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKP-----PLAPSGGTEGPEQP 624
                 +P+        L     +  PVS+ T++       P     PL  S      + P
Sbjct: 671  SPPPSKPRSPNPAAPALAAPAVVPGPVST-TDASPQSPPTPQTTLTPLQESPVISKDQSP 729

Query: 625  PPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTL-NPNAKEFNPTKPLLSVNKSTSTPT 683
            PP  P     PP    K E   E P A +  +  L +PN   + P  P     +  S   
Sbjct: 730  PPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPN---WPPPPPPAPEEQDLSMAD 786

Query: 684  SPGPRTHSTPSIPVLTAGQSGLYSPQYIS---------YIPQIHMGPAVQAPQMYPYPV- 733
             P P            AG SG  SP+ +S            QI    +   P   P P  
Sbjct: 787  FPPPEEAFFSVASPEPAGPSG--SPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAP 844

Query: 734  SNSVPGQQGKYRG------AKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSY 787
            ++S PG   K         +KG  PP R D   P   P ++Q             P  + 
Sbjct: 845  ASSAPGHVAKLPQKEPVGCSKGGGPP-REDVGAPLVTPSLLQMVRLRSVGAPGGAPTPAL 903

Query: 788  IPYNPQQFPGQPAMMQPMAHYPSQPVFAPM--LQSNPRMLTSGSHPQAIVSSSTPQ-YPS 844
             P  PQ+ P + A+        + PV AP   L +  R+          +SS+ P   P 
Sbjct: 904  GPSAPQK-PLRRALSG-----RASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPE 957

Query: 845  AEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHL 904
            AE   PQ+  +T    +   + +L   +P    T    Q        S  + +  QAP  
Sbjct: 958  AEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKK 1017

Query: 905  GSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPH 955
                P      P    G PP   P         S+P+   + A     LPH
Sbjct: 1018 SPKAPPPVARKPS--VGVPPPASP---------SYPRAEPLTAPPTNGLPH 1057



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 150/636 (23%), Positives = 208/636 (32%), Gaps = 116/636 (18%)

Query: 467  IGSAVPTSSASIPVTSSVSDPGV----GSISPASPKISLAPTDVKELSTKEPGRTLEPQE 522
            +G +  T +  +    S++ PG+    G   P SP +S++P     LS   P   L P  
Sbjct: 306  VGRSTGTRAPPLTRPMSLAVPGLTGGAGPAEPLSPAMSISP-QATYLSKLIPHAVLPPTV 364

Query: 523  LARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKE 582
                 G+               LR          S +   SL  F   +   +P+ +   
Sbjct: 365  DVVALGRC-------------SLRTLSRCSLHSASPASVRSLGRFSS-VSSPQPRSRHPS 410

Query: 583  VDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEG-PEQ--------PPPPCPSQTG 633
                 +S    S   S    VSD      L+  GG+EG PE         PPP   S  G
Sbjct: 411  -----SSSDTWSHSQSSDTIVSDGST---LSSKGGSEGQPESSTASNSVVPPPQGGSGRG 462

Query: 634  SPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTP 693
            SP            G  AE     ++  + +    +  L  + +    P  P  RTHS  
Sbjct: 463  SP----------SGGSTAEASDTLSIRSSGQLSGRSVSLRKLKR----PPPPPRRTHSLH 508

Query: 694  SIPVLTA-GQSGLYSPQYISYIPQIHMGPAVQ------APQMYPYPVSNSVPGQQGKYRG 746
               +    G  GL         PQ+   P         A    P P ++ VPG       
Sbjct: 509  QRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLS----- 563

Query: 747  AKGSLPPQRSDQ--------HQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQF--- 795
              GS  P RS +        +   S  P +     AGPP   A+P  +  P  P++    
Sbjct: 564  PGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPP---ASPGKAQPP-KPERVTSL 619

Query: 796  --PGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTS-------GSHPQAIVS-SSTPQYPSA 845
              PG        +   S    AP  +S P++LT          HP+     S  P  P +
Sbjct: 620  RSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRS 679

Query: 846  EQPTPQALYATV------------HQSYPHHATQLHAHQPQPATT----PTGSQPQSQHA 889
              P   AL A               QS P   T L   Q  P  +    P  S P S H 
Sbjct: 680  PNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHP 739

Query: 890  APSPVQHQ--AGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQS-PQSSFPQPAAVY 946
             P P +      +AP   S   ++ L  P      PP  PP P  Q    + FP P   +
Sbjct: 740  PPPPTKKPEVVVEAPS-ASETAEEPLQDPN----WPPPPPPAPEEQDLSMADFPPPEEAF 794

Query: 947  AIHHQQLPHGFTNMAHVTQ--AHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGA 1004
                   P G +    +    A   +  TA     PG+P PP       P S        
Sbjct: 795  FSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAK 854

Query: 1005 VPQSGVPALSASTPSPYPYIGHPQAPLPPPGELKIV 1040
            +PQ      S     P   +G   APL  P  L++V
Sbjct: 855  LPQKEPVGCSKGGGPPREDVG---APLVTPSLLQMV 887



 Score = 38.9 bits (89), Expect = 0.026
 Identities = 32/116 (27%), Positives = 46/116 (39%), Gaps = 10/116 (8%)

Query: 5   QPLQQPSQPQQPPPTQQ----AVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
           +PLQ P+ P  PPP  +    ++A  PP   +  +   P P   S +   P   +SP   
Sbjct: 762 EPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGS---PELVSSPAAS 818

Query: 61  PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSAR---GQSTGKGPPQSPV 113
             +A    ++        P PP P      PG  A    +   G S G GPP+  V
Sbjct: 819 SSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDV 874



 Score = 35.0 bits (79), Expect = 0.37
 Identities = 31/117 (26%), Positives = 43/117 (36%), Gaps = 10/117 (8%)

Query: 3   KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPG--PLATSAAPPGPPAAASPCLG 60
           KP+  QQP  P+ P       A   P   +P N  +PG  P  +   P  P    SP  G
Sbjct: 524 KPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSG 583

Query: 61  PVAAAGS------GLRRGAEGILAPQPPPPQQ--HQERPGAAAIGSARGQSTGKGPP 109
             + +G+      GL          QPP P++      PGA+   S     +    P
Sbjct: 584 YSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDP 640



 Score = 32.7 bits (73), Expect = 1.8
 Identities = 31/114 (27%), Positives = 42/114 (36%), Gaps = 17/114 (14%)

Query: 10  PSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAA----PPGPPAAASPCL-GPVAA 64
           PS+P+ P P   A+A             +PGP++T+ A    PP P    +P    PV +
Sbjct: 674 PSKPRSPNPAAPALAAPAV---------VPGPVSTTDASPQSPPTPQTTLTPLQESPVIS 724

Query: 65  AGSGLRRGAEGILAPQPPP---PQQHQERPGAAAIGSARGQSTGKGPPQSPVFE 115
                         P PPP   P+   E P A+       Q     PP  P  E
Sbjct: 725 KDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPE 778



 Score = 30.8 bits (68), Expect = 7.0
 Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 5/80 (6%)

Query: 33  PPNGGLPGPLATSAAPPGPPAAASPCL-GPVAAAGSGLRRGAEGILAPQPPPPQQHQERP 91
           PP+  +P P +   + P  P  A+P L  P    G      A    +PQ PP  Q    P
Sbjct: 661 PPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDA----SPQSPPTPQTTLTP 716

Query: 92  GAAAIGSARGQSTGKGPPQS 111
              +   ++ QS    PP S
Sbjct: 717 LQESPVISKDQSPPPSPPPS 736


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 128/566 (22%), Positives = 197/566 (34%), Gaps = 71/566 (12%)

Query: 394 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRP------SGETSVPPPPAVGRMYPP 447
           P  +A     GP+  +PK   P    +  S+    P      S  T+   P        P
Sbjct: 197 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 256

Query: 448 RSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVK 507
            +PK  AP       P  P   A  T+    P T+  +       +P +PK   APT   
Sbjct: 257 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPT--- 312

Query: 508 ELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPF 567
             + KEP  T  P+E      K P    ++      +     A  K  P++  E +    
Sbjct: 313 --TPKEPAPT-TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA---- 365

Query: 568 PPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP 627
            P   KE      KE       EP  +P ++K+   + KE     AP+     P  P  P
Sbjct: 366 -PTTPKEPAPTTTKEPSPTTPKEP--APTTTKSAPTTTKEP----APTTTKSAPTTPKEP 418

Query: 628 CPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNK--STSTPTSP 685
            P+ T  P         K+  P   +    T         P +P  +  K  + +TP  P
Sbjct: 419 SPTTTKEP----APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 474

Query: 686 GPRT--HSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK 743
            P T   + P+ P          +P+ ++  P     PA   P+     ++ + P +   
Sbjct: 475 APTTPKETAPTTPKKLTPT----TPEKLA--PTTPEKPAPTTPE----ELAPTTPEE--- 521

Query: 744 YRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQ 803
                    P  +   +PA   P  +AAA   P   A T      P  P+    +PA   
Sbjct: 522 ---------PTPTTPEEPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPK----EPAPTT 566

Query: 804 PMAHYPSQPV-FAPMLQSNPRMLT-SGSHPQAIVSSST--PQYPSAEQPTPQALYATVHQ 859
           P    P+ P   AP     P   T     P+ +  ++T  P   + ++P P     T   
Sbjct: 567 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA-P 625

Query: 860 SYPHHATQLHAHQPQPATTPTGSQPQS-QHAAPSPVQHQAGQ--APHLGSGQPQQNLYHP 916
           + P         +P P TTP G+ P + +  AP+  +  A +  AP    G        P
Sbjct: 626 TTPKEPAPTTPKEPAP-TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 684

Query: 917 GALT--GTPPSLPPGPSAQSPQSSFP 940
              T   T P+ P  P+  +P+   P
Sbjct: 685 APTTPKETAPTTPKEPAPTTPKKPAP 710



 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 137/637 (21%), Positives = 200/637 (31%), Gaps = 84/637 (13%)

Query: 419  AKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASI 478
            +K L+ P+  P  ET+   P     +  P+ P    P   +++ P+ P     PT+  S 
Sbjct: 191  SKVLAKPT--PKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEP----TPTTIKSA 240

Query: 479  PVTSSVSDPGVGSISPASPKISLAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQN 535
            P T            PA      APT  KE    +TKEP  T  P+E A    K P    
Sbjct: 241  PTTPK---------EPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKEPA--- 287

Query: 536  EQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSP 595
                                  S+P    +P P    K  P    KE       EP  +P
Sbjct: 288  -----------------PTTTKSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEP--TP 327

Query: 596  VSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG-SPPVGLIKGEDKDEGPVAEQV 654
             + K  + + KE  P          P++P P  P +   + P        K+  P   + 
Sbjct: 328  TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 387

Query: 655  KKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYI 714
               T   +A          +   + +TP  P P T   P+    T  +    +P+     
Sbjct: 388  PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTTPK--KPA 443

Query: 715  PQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAA 774
            P     PA   P+  P P +   P        A  + P + +        P   +  A  
Sbjct: 444  PTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTPEKLAPT 501

Query: 775  GPPLVAATPYSSYIPYNPQQ----FPGQPAMMQPMAHYPSQPVF-APMLQSNPRMLTSGS 829
             P   A T      P  P++     P +PA   P A  P+ P   AP     P   T   
Sbjct: 502  TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 561

Query: 830  HPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHA 889
                    + P  P    PT      T+ +  P    +    +  P TT   +       
Sbjct: 562  PAPTTPKETAPTTPKGTAPT------TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 615

Query: 890  APSPVQHQAGQAPHLGSGQPQQNLYHPGALT--GTPPSLPPGPSAQSPQSSFPQPAAVYA 947
            AP+  +   G AP             P   T  GT P+    P+  +P+   P+  A   
Sbjct: 616  APTTPK---GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 672

Query: 948  IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPH----------PPQVMLLHPPQSH 997
                + P   T+         +T  T    P P  P           PP    +  P + 
Sbjct: 673  ---TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTT 729

Query: 998  GGPPQ-GAVPQSGVPALSASTPSPYPYIGHPQAPLPP 1033
              P      P    P LSA  P+P      P+ P  P
Sbjct: 730  KEPTTIHKSPDESTPELSAE-PTPKALENSPKEPGVP 765



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 107/502 (21%), Positives = 162/502 (32%), Gaps = 67/502 (13%)

Query: 406 SRMSPKAQRPLRGAKTLSSPSN--RPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCP 463
           ++ +P   +      T S+P+    PS  T+  P P   +   P +PK  AP       P
Sbjct: 393 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 452

Query: 464 EPPIGSAVPTSSASIPVTSSVSDPGV-GSISPASPKISLAPTDVKEL--STKEPGRTLEP 520
             P   A  T+    P T     P      +P +PK  L PT  ++L  +T E      P
Sbjct: 453 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTP 511

Query: 521 QELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFP-------PRILK 573
           +ELA    + P     ++                  +++P    +P P       P   K
Sbjct: 512 EELAPTTPEEPTPTTPEEPAP-----------TTPKAAAPNTPKEPAPTTPKEPAPTTPK 560

Query: 574 EEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG 633
           E      KE      + P G+  ++  E       KP       T   E     C     
Sbjct: 561 EPAPTTPKET---APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 617

Query: 634 SPPVGLIKGEDKDEGPV-----AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPR 688
           + P G      K+  P      A    K T     KE  PT P     K  +  T+ GP 
Sbjct: 618 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP- 676

Query: 689 THSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAK 748
           T +T   P  T  +            P     PA   P+  P P +   P          
Sbjct: 677 TSTTSDKPAPTTPK---------ETAPTTPKEPAPTTPKK-PAPTTPETP---------- 716

Query: 749 GSLPPQRSDQHQPASA--PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMA 806
              PP  S+   P +   P  +  +     P ++A P    +  +P++ PG P    P A
Sbjct: 717 ---PPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE-PGVPTTKTPAA 772

Query: 807 HYPSQPVFAP------MLQSNPRMLTSGSHPQAIVSSSTPQYPSAE--QPTPQALYATVH 858
             P     A        L++ P   T+        +++T +   ++    T Q    T  
Sbjct: 773 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 832

Query: 859 QSYPHHATQLHAHQPQPATTPT 880
            + P   T L      P  T T
Sbjct: 833 DTTPFKITTLKTTTLAPKVTTT 854



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 113/544 (20%), Positives = 176/544 (32%), Gaps = 67/544 (12%)

Query: 381 PRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA 440
           P+ P       P P +        P   +P  + P        +P+       + P  PA
Sbjct: 306 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 365

Query: 441 VGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKIS 500
                 P    +  P+P +   P        PT++ S P T+    P     +P +PK  
Sbjct: 366 PTTPKEPAPTTTKEPSPTTPKEP-------APTTTKSAPTTTKEPAPTTTKSAPTTPK-E 417

Query: 501 LAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPS 557
            +PT  KE    + KEP  T  P++ A    K P     ++       +      K    
Sbjct: 418 PSPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 476

Query: 558 SSPENSLDPFPPRILKEEPK---GKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAP 614
           ++P+ +    P ++    P+       E     T E +      +    + +E  P    
Sbjct: 477 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 536

Query: 615 SGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGP--VAEQVKKSTLNPNAKEFNPTKPL 672
           +     P++P P  P +    P      E     P   A    K T     KE  PT P 
Sbjct: 537 AAAPNTPKEPAPTTPKE----PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 592

Query: 673 LSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP 732
               K  +  T+  P T +T   P                  P    G A   P+  P P
Sbjct: 593 KPAPKELAPTTTKEP-TSTTCDKPA-----------------PTTPKGTAPTTPK-EPAP 633

Query: 733 VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLV---AATPYSSYIP 789
            +   P         KG+ P   +   +PA   P   A     P       +T      P
Sbjct: 634 TTPKEPAP----TTPKGTAP---TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 686

Query: 790 YNPQQ----FPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSS---STPQY 842
             P++     P +PA   P    P+ P   P   S     T+   P  I  S   STP+ 
Sbjct: 687 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 746

Query: 843 PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTG--------SQPQSQHAAPSPV 894
             + +PTP+AL  +  +          A +P+  TT           + P++  AAP   
Sbjct: 747 --SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 804

Query: 895 QHQA 898
           +  A
Sbjct: 805 KETA 808



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 73/315 (23%), Positives = 110/315 (34%), Gaps = 59/315 (18%)

Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464
           P+  +PK   P   A T +     P+  TS  P P   +   P +PK  AP       P 
Sbjct: 655 PAPTTPKKPAPKELAPTTTKG---PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 711

Query: 465 PPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPT-DVKELSTKEPGRTLEPQEL 523
            P      TS  S P T+        S   ++P++S  PT    E S KEPG    P   
Sbjct: 712 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG---VPTTK 768

Query: 524 ARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEV 583
              A K       + +    +LR           ++PE +     P++ KE     EK  
Sbjct: 769 TPAATKPEMTTTAKDKTTERDLR-----------TTPETT--TAAPKMTKETATTTEKTT 815

Query: 584 DGLLTSEPMGSPVSSKTESVSDKEDKP---------PLAPSGGT-----------EGPEQ 623
           +  +T+       +++  S + ++  P          LAP   T             PE+
Sbjct: 816 ESKITA------TTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEE 869

Query: 624 PPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP- 682
              P    T S          K   P  ++  K+   P + +   T P +   K+T TP 
Sbjct: 870 TAKPKDRATNS----------KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPR 919

Query: 683 --TSPGPRTHSTPSI 695
             TS  P  + T  I
Sbjct: 920 KMTSTMPELNPTSRI 934



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 100/473 (21%), Positives = 145/473 (30%), Gaps = 50/473 (10%)

Query: 589  SEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEG 648
            S P  S  S +T    +KE       +  T           + +      + K   KD  
Sbjct: 129  SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 188

Query: 649  PVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSP 708
            P ++ + K T  P A E     P L+  K   TPT+P     +TP  P  T  +S   +P
Sbjct: 189  PTSKVLAKPT--PKA-ETTTKGPALTTPKEP-TPTTPKEPASTTPKEPTPTTIKSAPTTP 244

Query: 709  QYIS-------------YIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQR 755
            +  +               P     PA   P+  P P +   P              P  
Sbjct: 245  KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPAP 303

Query: 756  SDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFA 815
            +   +PA   P   A      P    TP +   P    + P      +P    P +P  A
Sbjct: 304  TTPKKPAPTTPKEPAPTTPKEP----TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP--A 357

Query: 816  PMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHA----H 871
            P     P   T            +P  P    PT      T  +  P   T   A     
Sbjct: 358  PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE-PAPTTTKSAPTTPK 416

Query: 872  QPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGT---PPSLPP 928
            +P P TT   +    +  AP+  +  A   P     +P        A T T    P+ P 
Sbjct: 417  EPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK----EPAPTTPKEPAPTTTKKPAPTTPK 472

Query: 929  GPSAQSPQSSFP-QPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPP----PHPGAP 983
             P+  +P+ + P  P  +     ++L          T        T   P    P   AP
Sbjct: 473  EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 532

Query: 984  HPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTP-SPYPYIGHPQAPLPPPG 1035
              P+    + P+     P    P+   P    +TP  P P      AP  P G
Sbjct: 533  TTPKAAAPNTPKE----PAPTTPKEPAP----TTPKEPAPTTPKETAPTTPKG 577


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 128/566 (22%), Positives = 197/566 (34%), Gaps = 71/566 (12%)

Query: 394 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRP------SGETSVPPPPAVGRMYPP 447
           P  +A     GP+  +PK   P    +  S+    P      S  T+   P        P
Sbjct: 238 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 297

Query: 448 RSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVK 507
            +PK  AP       P  P   A  T+    P T+  +       +P +PK   APT   
Sbjct: 298 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPT--- 353

Query: 508 ELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPF 567
             + KEP  T  P+E      K P    ++      +     A  K  P++  E +    
Sbjct: 354 --TPKEPAPT-TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA---- 406

Query: 568 PPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP 627
            P   KE      KE       EP  +P ++K+   + KE     AP+     P  P  P
Sbjct: 407 -PTTPKEPAPTTTKEPSPTTPKEP--APTTTKSAPTTTKEP----APTTTKSAPTTPKEP 459

Query: 628 CPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNK--STSTPTSP 685
            P+ T  P         K+  P   +    T         P +P  +  K  + +TP  P
Sbjct: 460 SPTTTKEP----APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 515

Query: 686 GPRT--HSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK 743
            P T   + P+ P          +P+ ++  P     PA   P+     ++ + P +   
Sbjct: 516 APTTPKETAPTTPKKLTPT----TPEKLA--PTTPEKPAPTTPE----ELAPTTPEE--- 562

Query: 744 YRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQ 803
                    P  +   +PA   P  +AAA   P   A T      P  P+    +PA   
Sbjct: 563 ---------PTPTTPEEPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPK----EPAPTT 607

Query: 804 PMAHYPSQPV-FAPMLQSNPRMLT-SGSHPQAIVSSST--PQYPSAEQPTPQALYATVHQ 859
           P    P+ P   AP     P   T     P+ +  ++T  P   + ++P P     T   
Sbjct: 608 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA-P 666

Query: 860 SYPHHATQLHAHQPQPATTPTGSQPQS-QHAAPSPVQHQAGQ--APHLGSGQPQQNLYHP 916
           + P         +P P TTP G+ P + +  AP+  +  A +  AP    G        P
Sbjct: 667 TTPKEPAPTTPKEPAP-TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 725

Query: 917 GALT--GTPPSLPPGPSAQSPQSSFP 940
              T   T P+ P  P+  +P+   P
Sbjct: 726 APTTPKETAPTTPKEPAPTTPKKPAP 751



 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 137/637 (21%), Positives = 200/637 (31%), Gaps = 84/637 (13%)

Query: 419  AKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASI 478
            +K L+ P+  P  ET+   P     +  P+ P    P   +++ P+ P     PT+  S 
Sbjct: 232  SKVLAKPT--PKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEP----TPTTIKSA 281

Query: 479  PVTSSVSDPGVGSISPASPKISLAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQN 535
            P T            PA      APT  KE    +TKEP  T  P+E A    K P    
Sbjct: 282  PTTPK---------EPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKEPA--- 328

Query: 536  EQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSP 595
                                  S+P    +P P    K  P    KE       EP  +P
Sbjct: 329  -----------------PTTTKSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEP--TP 368

Query: 596  VSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG-SPPVGLIKGEDKDEGPVAEQV 654
             + K  + + KE  P          P++P P  P +   + P        K+  P   + 
Sbjct: 369  TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 428

Query: 655  KKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYI 714
               T   +A          +   + +TP  P P T   P+    T  +    +P+     
Sbjct: 429  PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTTPK--KPA 484

Query: 715  PQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAA 774
            P     PA   P+  P P +   P        A  + P + +        P   +  A  
Sbjct: 485  PTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTPEKLAPT 542

Query: 775  GPPLVAATPYSSYIPYNPQQ----FPGQPAMMQPMAHYPSQPVF-APMLQSNPRMLTSGS 829
             P   A T      P  P++     P +PA   P A  P+ P   AP     P   T   
Sbjct: 543  TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 602

Query: 830  HPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHA 889
                    + P  P    PT      T+ +  P    +    +  P TT   +       
Sbjct: 603  PAPTTPKETAPTTPKGTAPT------TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 656

Query: 890  APSPVQHQAGQAPHLGSGQPQQNLYHPGALT--GTPPSLPPGPSAQSPQSSFPQPAAVYA 947
            AP+  +   G AP             P   T  GT P+    P+  +P+   P+  A   
Sbjct: 657  APTTPK---GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 713

Query: 948  IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPH----------PPQVMLLHPPQSH 997
                + P   T+         +T  T    P P  P           PP    +  P + 
Sbjct: 714  ---TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTT 770

Query: 998  GGPPQ-GAVPQSGVPALSASTPSPYPYIGHPQAPLPP 1033
              P      P    P LSA  P+P      P+ P  P
Sbjct: 771  KEPTTIHKSPDESTPELSAE-PTPKALENSPKEPGVP 806



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 107/502 (21%), Positives = 162/502 (32%), Gaps = 67/502 (13%)

Query: 406 SRMSPKAQRPLRGAKTLSSPSN--RPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCP 463
           ++ +P   +      T S+P+    PS  T+  P P   +   P +PK  AP       P
Sbjct: 434 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 493

Query: 464 EPPIGSAVPTSSASIPVTSSVSDPGV-GSISPASPKISLAPTDVKEL--STKEPGRTLEP 520
             P   A  T+    P T     P      +P +PK  L PT  ++L  +T E      P
Sbjct: 494 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTP 552

Query: 521 QELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFP-------PRILK 573
           +ELA    + P     ++                  +++P    +P P       P   K
Sbjct: 553 EELAPTTPEEPTPTTPEEPAP-----------TTPKAAAPNTPKEPAPTTPKEPAPTTPK 601

Query: 574 EEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG 633
           E      KE      + P G+  ++  E       KP       T   E     C     
Sbjct: 602 EPAPTTPKET---APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 658

Query: 634 SPPVGLIKGEDKDEGPV-----AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPR 688
           + P G      K+  P      A    K T     KE  PT P     K  +  T+ GP 
Sbjct: 659 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP- 717

Query: 689 THSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAK 748
           T +T   P  T  +            P     PA   P+  P P +   P          
Sbjct: 718 TSTTSDKPAPTTPK---------ETAPTTPKEPAPTTPKK-PAPTTPETP---------- 757

Query: 749 GSLPPQRSDQHQPASA--PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMA 806
              PP  S+   P +   P  +  +     P ++A P    +  +P++ PG P    P A
Sbjct: 758 ---PPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE-PGVPTTKTPAA 813

Query: 807 HYPSQPVFAP------MLQSNPRMLTSGSHPQAIVSSSTPQYPSAE--QPTPQALYATVH 858
             P     A        L++ P   T+        +++T +   ++    T Q    T  
Sbjct: 814 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 873

Query: 859 QSYPHHATQLHAHQPQPATTPT 880
            + P   T L      P  T T
Sbjct: 874 DTTPFKITTLKTTTLAPKVTTT 895



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 113/544 (20%), Positives = 176/544 (32%), Gaps = 67/544 (12%)

Query: 381 PRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA 440
           P+ P       P P +        P   +P  + P        +P+       + P  PA
Sbjct: 347 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 406

Query: 441 VGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKIS 500
                 P    +  P+P +   P        PT++ S P T+    P     +P +PK  
Sbjct: 407 PTTPKEPAPTTTKEPSPTTPKEP-------APTTTKSAPTTTKEPAPTTTKSAPTTPK-E 458

Query: 501 LAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPS 557
            +PT  KE    + KEP  T  P++ A    K P     ++       +      K    
Sbjct: 459 PSPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 517

Query: 558 SSPENSLDPFPPRILKEEPK---GKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAP 614
           ++P+ +    P ++    P+       E     T E +      +    + +E  P    
Sbjct: 518 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 577

Query: 615 SGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGP--VAEQVKKSTLNPNAKEFNPTKPL 672
           +     P++P P  P +    P      E     P   A    K T     KE  PT P 
Sbjct: 578 AAAPNTPKEPAPTTPKE----PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 633

Query: 673 LSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP 732
               K  +  T+  P T +T   P                  P    G A   P+  P P
Sbjct: 634 KPAPKELAPTTTKEP-TSTTCDKPA-----------------PTTPKGTAPTTPK-EPAP 674

Query: 733 VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLV---AATPYSSYIP 789
            +   P         KG+ P   +   +PA   P   A     P       +T      P
Sbjct: 675 TTPKEPAP----TTPKGTAP---TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 727

Query: 790 YNPQQ----FPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSS---STPQY 842
             P++     P +PA   P    P+ P   P   S     T+   P  I  S   STP+ 
Sbjct: 728 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 787

Query: 843 PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTG--------SQPQSQHAAPSPV 894
             + +PTP+AL  +  +          A +P+  TT           + P++  AAP   
Sbjct: 788 --SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 845

Query: 895 QHQA 898
           +  A
Sbjct: 846 KETA 849



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 73/315 (23%), Positives = 110/315 (34%), Gaps = 59/315 (18%)

Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464
           P+  +PK   P   A T +     P+  TS  P P   +   P +PK  AP       P 
Sbjct: 696 PAPTTPKKPAPKELAPTTTKG---PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 752

Query: 465 PPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPT-DVKELSTKEPGRTLEPQEL 523
            P      TS  S P T+        S   ++P++S  PT    E S KEPG    P   
Sbjct: 753 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG---VPTTK 809

Query: 524 ARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEV 583
              A K       + +    +LR           ++PE +     P++ KE     EK  
Sbjct: 810 TPAATKPEMTTTAKDKTTERDLR-----------TTPETT--TAAPKMTKETATTTEKTT 856

Query: 584 DGLLTSEPMGSPVSSKTESVSDKEDKP---------PLAPSGGT-----------EGPEQ 623
           +  +T+       +++  S + ++  P          LAP   T             PE+
Sbjct: 857 ESKITA------TTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEE 910

Query: 624 PPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP- 682
              P    T S          K   P  ++  K+   P + +   T P +   K+T TP 
Sbjct: 911 TAKPKDRATNS----------KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPR 960

Query: 683 --TSPGPRTHSTPSI 695
             TS  P  + T  I
Sbjct: 961 KMTSTMPELNPTSRI 975



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 100/473 (21%), Positives = 145/473 (30%), Gaps = 50/473 (10%)

Query: 589  SEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEG 648
            S P  S  S +T    +KE       +  T           + +      + K   KD  
Sbjct: 170  SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 229

Query: 649  PVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSP 708
            P ++ + K T  P A E     P L+  K   TPT+P     +TP  P  T  +S   +P
Sbjct: 230  PTSKVLAKPT--PKA-ETTTKGPALTTPKEP-TPTTPKEPASTTPKEPTPTTIKSAPTTP 285

Query: 709  QYIS-------------YIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQR 755
            +  +               P     PA   P+  P P +   P              P  
Sbjct: 286  KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPAP 344

Query: 756  SDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFA 815
            +   +PA   P   A      P    TP +   P    + P      +P    P +P  A
Sbjct: 345  TTPKKPAPTTPKEPAPTTPKEP----TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP--A 398

Query: 816  PMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHA----H 871
            P     P   T            +P  P    PT      T  +  P   T   A     
Sbjct: 399  PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE-PAPTTTKSAPTTPK 457

Query: 872  QPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGT---PPSLPP 928
            +P P TT   +    +  AP+  +  A   P     +P        A T T    P+ P 
Sbjct: 458  EPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK----EPAPTTPKEPAPTTTKKPAPTTPK 513

Query: 929  GPSAQSPQSSFP-QPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPP----PHPGAP 983
             P+  +P+ + P  P  +     ++L          T        T   P    P   AP
Sbjct: 514  EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 573

Query: 984  HPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTP-SPYPYIGHPQAPLPPPG 1035
              P+    + P+     P    P+   P    +TP  P P      AP  P G
Sbjct: 574  TTPKAAAPNTPKE----PAPTTPKEPAP----TTPKEPAPTTPKETAPTTPKG 618


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 128/566 (22%), Positives = 197/566 (34%), Gaps = 71/566 (12%)

Query: 394 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRP------SGETSVPPPPAVGRMYPP 447
           P  +A     GP+  +PK   P    +  S+    P      S  T+   P        P
Sbjct: 290 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 349

Query: 448 RSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVK 507
            +PK  AP       P  P   A  T+    P T+  +       +P +PK   APT   
Sbjct: 350 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPT--- 405

Query: 508 ELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPF 567
             + KEP  T  P+E      K P    ++      +     A  K  P++  E +    
Sbjct: 406 --TPKEPAPT-TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA---- 458

Query: 568 PPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP 627
            P   KE      KE       EP  +P ++K+   + KE     AP+     P  P  P
Sbjct: 459 -PTTPKEPAPTTTKEPSPTTPKEP--APTTTKSAPTTTKEP----APTTTKSAPTTPKEP 511

Query: 628 CPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNK--STSTPTSP 685
            P+ T  P         K+  P   +    T         P +P  +  K  + +TP  P
Sbjct: 512 SPTTTKEP----APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 567

Query: 686 GPRT--HSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK 743
            P T   + P+ P          +P+ ++  P     PA   P+     ++ + P +   
Sbjct: 568 APTTPKETAPTTPKKLTPT----TPEKLA--PTTPEKPAPTTPE----ELAPTTPEE--- 614

Query: 744 YRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQ 803
                    P  +   +PA   P  +AAA   P   A T      P  P+    +PA   
Sbjct: 615 ---------PTPTTPEEPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPK----EPAPTT 659

Query: 804 PMAHYPSQPV-FAPMLQSNPRMLT-SGSHPQAIVSSST--PQYPSAEQPTPQALYATVHQ 859
           P    P+ P   AP     P   T     P+ +  ++T  P   + ++P P     T   
Sbjct: 660 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA-P 718

Query: 860 SYPHHATQLHAHQPQPATTPTGSQPQS-QHAAPSPVQHQAGQ--APHLGSGQPQQNLYHP 916
           + P         +P P TTP G+ P + +  AP+  +  A +  AP    G        P
Sbjct: 719 TTPKEPAPTTPKEPAP-TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 777

Query: 917 GALT--GTPPSLPPGPSAQSPQSSFP 940
              T   T P+ P  P+  +P+   P
Sbjct: 778 APTTPKETAPTTPKEPAPTTPKKPAP 803



 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 137/637 (21%), Positives = 200/637 (31%), Gaps = 84/637 (13%)

Query: 419  AKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASI 478
            +K L+ P+  P  ET+   P     +  P+ P    P   +++ P+ P     PT+  S 
Sbjct: 284  SKVLAKPT--PKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEP----TPTTIKSA 333

Query: 479  PVTSSVSDPGVGSISPASPKISLAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQN 535
            P T            PA      APT  KE    +TKEP  T  P+E A    K P    
Sbjct: 334  PTTPK---------EPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKEPA--- 380

Query: 536  EQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSP 595
                                  S+P    +P P    K  P    KE       EP  +P
Sbjct: 381  -----------------PTTTKSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEP--TP 420

Query: 596  VSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG-SPPVGLIKGEDKDEGPVAEQV 654
             + K  + + KE  P          P++P P  P +   + P        K+  P   + 
Sbjct: 421  TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 480

Query: 655  KKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYI 714
               T   +A          +   + +TP  P P T   P+    T  +    +P+     
Sbjct: 481  PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTTPK--KPA 536

Query: 715  PQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAA 774
            P     PA   P+  P P +   P        A  + P + +        P   +  A  
Sbjct: 537  PTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTPEKLAPT 594

Query: 775  GPPLVAATPYSSYIPYNPQQ----FPGQPAMMQPMAHYPSQPVF-APMLQSNPRMLTSGS 829
             P   A T      P  P++     P +PA   P A  P+ P   AP     P   T   
Sbjct: 595  TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 654

Query: 830  HPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHA 889
                    + P  P    PT      T+ +  P    +    +  P TT   +       
Sbjct: 655  PAPTTPKETAPTTPKGTAPT------TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 708

Query: 890  APSPVQHQAGQAPHLGSGQPQQNLYHPGALT--GTPPSLPPGPSAQSPQSSFPQPAAVYA 947
            AP+  +   G AP             P   T  GT P+    P+  +P+   P+  A   
Sbjct: 709  APTTPK---GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 765

Query: 948  IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPH----------PPQVMLLHPPQSH 997
                + P   T+         +T  T    P P  P           PP    +  P + 
Sbjct: 766  ---TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTT 822

Query: 998  GGPPQ-GAVPQSGVPALSASTPSPYPYIGHPQAPLPP 1033
              P      P    P LSA  P+P      P+ P  P
Sbjct: 823  KEPTTIHKSPDESTPELSAE-PTPKALENSPKEPGVP 858



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 107/502 (21%), Positives = 162/502 (32%), Gaps = 67/502 (13%)

Query: 406 SRMSPKAQRPLRGAKTLSSPSN--RPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCP 463
           ++ +P   +      T S+P+    PS  T+  P P   +   P +PK  AP       P
Sbjct: 486 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 545

Query: 464 EPPIGSAVPTSSASIPVTSSVSDPGV-GSISPASPKISLAPTDVKEL--STKEPGRTLEP 520
             P   A  T+    P T     P      +P +PK  L PT  ++L  +T E      P
Sbjct: 546 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTP 604

Query: 521 QELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFP-------PRILK 573
           +ELA    + P     ++                  +++P    +P P       P   K
Sbjct: 605 EELAPTTPEEPTPTTPEEPAP-----------TTPKAAAPNTPKEPAPTTPKEPAPTTPK 653

Query: 574 EEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG 633
           E      KE      + P G+  ++  E       KP       T   E     C     
Sbjct: 654 EPAPTTPKET---APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 710

Query: 634 SPPVGLIKGEDKDEGPV-----AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPR 688
           + P G      K+  P      A    K T     KE  PT P     K  +  T+ GP 
Sbjct: 711 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP- 769

Query: 689 THSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAK 748
           T +T   P  T  +            P     PA   P+  P P +   P          
Sbjct: 770 TSTTSDKPAPTTPK---------ETAPTTPKEPAPTTPKK-PAPTTPETP---------- 809

Query: 749 GSLPPQRSDQHQPASA--PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMA 806
              PP  S+   P +   P  +  +     P ++A P    +  +P++ PG P    P A
Sbjct: 810 ---PPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE-PGVPTTKTPAA 865

Query: 807 HYPSQPVFAP------MLQSNPRMLTSGSHPQAIVSSSTPQYPSAE--QPTPQALYATVH 858
             P     A        L++ P   T+        +++T +   ++    T Q    T  
Sbjct: 866 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 925

Query: 859 QSYPHHATQLHAHQPQPATTPT 880
            + P   T L      P  T T
Sbjct: 926 DTTPFKITTLKTTTLAPKVTTT 947



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 113/544 (20%), Positives = 176/544 (32%), Gaps = 67/544 (12%)

Query: 381 PRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA 440
           P+ P       P P +        P   +P  + P        +P+       + P  PA
Sbjct: 399 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 458

Query: 441 VGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKIS 500
                 P    +  P+P +   P        PT++ S P T+    P     +P +PK  
Sbjct: 459 PTTPKEPAPTTTKEPSPTTPKEP-------APTTTKSAPTTTKEPAPTTTKSAPTTPK-E 510

Query: 501 LAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPS 557
            +PT  KE    + KEP  T  P++ A    K P     ++       +      K    
Sbjct: 511 PSPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 569

Query: 558 SSPENSLDPFPPRILKEEPK---GKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAP 614
           ++P+ +    P ++    P+       E     T E +      +    + +E  P    
Sbjct: 570 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 629

Query: 615 SGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGP--VAEQVKKSTLNPNAKEFNPTKPL 672
           +     P++P P  P +    P      E     P   A    K T     KE  PT P 
Sbjct: 630 AAAPNTPKEPAPTTPKE----PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 685

Query: 673 LSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP 732
               K  +  T+  P T +T   P                  P    G A   P+  P P
Sbjct: 686 KPAPKELAPTTTKEP-TSTTCDKPA-----------------PTTPKGTAPTTPK-EPAP 726

Query: 733 VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLV---AATPYSSYIP 789
            +   P         KG+ P   +   +PA   P   A     P       +T      P
Sbjct: 727 TTPKEPAP----TTPKGTAP---TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 779

Query: 790 YNPQQ----FPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSS---STPQY 842
             P++     P +PA   P    P+ P   P   S     T+   P  I  S   STP+ 
Sbjct: 780 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 839

Query: 843 PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTG--------SQPQSQHAAPSPV 894
             + +PTP+AL  +  +          A +P+  TT           + P++  AAP   
Sbjct: 840 --SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 897

Query: 895 QHQA 898
           +  A
Sbjct: 898 KETA 901



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 130/637 (20%), Positives = 203/637 (31%), Gaps = 64/637 (10%)

Query: 432  ETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGS 491
            E   P  P   +  PP S  S      +   P+PP          S  +T   S      
Sbjct: 65   EVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQE 124

Query: 492  ISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGA- 550
             S +S   S + T  K  S+K      E Q+  ++         ++   +   + + G+ 
Sbjct: 125  SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSG 184

Query: 551  ----QFKLQP--SSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVS 604
                 FK+    +S+ +++     P+I   +P      +     +    S   +K  +V 
Sbjct: 185  LDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVE 244

Query: 605  DKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAK 664
             KE       +  T+G E+      +Q+      + K   KD  P ++ + K T  P A 
Sbjct: 245  TKETTTTNKQTS-TDGKEKTTSAKETQS------IEKTSAKDLAPTSKVLAKPT--PKA- 294

Query: 665  EFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYIS------------ 712
            E     P L+  K   TPT+P     +TP  P  T  +S   +P+  +            
Sbjct: 295  ETTTKGPALTTPKEP-TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPK 353

Query: 713  -YIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAA 771
               P     PA   P+  P P +   P              P  +   +PA   P   A 
Sbjct: 354  EPAPTTTKEPAPTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP 412

Query: 772  AAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHP 831
                 P    TP +   P    + P      +P    P +P  AP     P   T     
Sbjct: 413  TTPKEP----TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP--APTTPKEPAPTTPKEPA 466

Query: 832  QAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHA----HQPQPATTPTGSQPQSQ 887
                   +P  P    PT      T  +  P   T   A     +P P TT   +    +
Sbjct: 467  PTTTKEPSPTTPKEPAPTTTKSAPTTTKE-PAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 525

Query: 888  HAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGT---PPSLPPGPSAQSPQSSFP-QPA 943
              AP+  +  A   P     +P        A T T    P+ P  P+  +P+ + P  P 
Sbjct: 526  EPAPTTPKKPAPTTPK----EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 581

Query: 944  AVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPP----PHPGAPHPPQVMLLHPPQSHGG 999
             +     ++L          T        T   P    P   AP  P+    + P+    
Sbjct: 582  KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE--- 638

Query: 1000 PPQGAVPQSGVPALSASTP-SPYPYIGHPQAPLPPPG 1035
             P    P+   P    +TP  P P      AP  P G
Sbjct: 639  -PAPTTPKEPAP----TTPKEPAPTTPKETAPTTPKG 670



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 73/315 (23%), Positives = 110/315 (34%), Gaps = 59/315 (18%)

Query: 405  PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464
            P+  +PK   P   A T +     P+  TS  P P   +   P +PK  AP       P 
Sbjct: 748  PAPTTPKKPAPKELAPTTTKG---PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 804

Query: 465  PPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPT-DVKELSTKEPGRTLEPQEL 523
             P      TS  S P T+        S   ++P++S  PT    E S KEPG    P   
Sbjct: 805  TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG---VPTTK 861

Query: 524  ARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEV 583
               A K       + +    +LR           ++PE +     P++ KE     EK  
Sbjct: 862  TPAATKPEMTTTAKDKTTERDLR-----------TTPETT--TAAPKMTKETATTTEKTT 908

Query: 584  DGLLTSEPMGSPVSSKTESVSDKEDKP---------PLAPSGGT-----------EGPEQ 623
            +  +T+       +++  S + ++  P          LAP   T             PE+
Sbjct: 909  ESKITA------TTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEE 962

Query: 624  PPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP- 682
               P    T S          K   P  ++  K+   P + +   T P +   K+T TP 
Sbjct: 963  TAKPKDRATNS----------KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPR 1012

Query: 683  --TSPGPRTHSTPSI 695
              TS  P  + T  I
Sbjct: 1013 KMTSTMPELNPTSRI 1027


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 128/566 (22%), Positives = 197/566 (34%), Gaps = 71/566 (12%)

Query: 394 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRP------SGETSVPPPPAVGRMYPP 447
           P  +A     GP+  +PK   P    +  S+    P      S  T+   P        P
Sbjct: 331 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 390

Query: 448 RSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVK 507
            +PK  AP       P  P   A  T+    P T+  +       +P +PK   APT   
Sbjct: 391 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPT--- 446

Query: 508 ELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPF 567
             + KEP  T  P+E      K P    ++      +     A  K  P++  E +    
Sbjct: 447 --TPKEPAPT-TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA---- 499

Query: 568 PPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP 627
            P   KE      KE       EP  +P ++K+   + KE     AP+     P  P  P
Sbjct: 500 -PTTPKEPAPTTTKEPSPTTPKEP--APTTTKSAPTTTKEP----APTTTKSAPTTPKEP 552

Query: 628 CPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNK--STSTPTSP 685
            P+ T  P         K+  P   +    T         P +P  +  K  + +TP  P
Sbjct: 553 SPTTTKEP----APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 608

Query: 686 GPRT--HSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK 743
            P T   + P+ P          +P+ ++  P     PA   P+     ++ + P +   
Sbjct: 609 APTTPKETAPTTPKKLTPT----TPEKLA--PTTPEKPAPTTPE----ELAPTTPEE--- 655

Query: 744 YRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQ 803
                    P  +   +PA   P  +AAA   P   A T      P  P+    +PA   
Sbjct: 656 ---------PTPTTPEEPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPK----EPAPTT 700

Query: 804 PMAHYPSQPV-FAPMLQSNPRMLT-SGSHPQAIVSSST--PQYPSAEQPTPQALYATVHQ 859
           P    P+ P   AP     P   T     P+ +  ++T  P   + ++P P     T   
Sbjct: 701 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA-P 759

Query: 860 SYPHHATQLHAHQPQPATTPTGSQPQS-QHAAPSPVQHQAGQ--APHLGSGQPQQNLYHP 916
           + P         +P P TTP G+ P + +  AP+  +  A +  AP    G        P
Sbjct: 760 TTPKEPAPTTPKEPAP-TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 818

Query: 917 GALT--GTPPSLPPGPSAQSPQSSFP 940
              T   T P+ P  P+  +P+   P
Sbjct: 819 APTTPKETAPTTPKEPAPTTPKKPAP 844



 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 137/637 (21%), Positives = 200/637 (31%), Gaps = 84/637 (13%)

Query: 419  AKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASI 478
            +K L+ P+  P  ET+   P     +  P+ P    P   +++ P+ P     PT+  S 
Sbjct: 325  SKVLAKPT--PKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEP----TPTTIKSA 374

Query: 479  PVTSSVSDPGVGSISPASPKISLAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQN 535
            P T            PA      APT  KE    +TKEP  T  P+E A    K P    
Sbjct: 375  PTTPK---------EPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKEPA--- 421

Query: 536  EQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSP 595
                                  S+P    +P P    K  P    KE       EP  +P
Sbjct: 422  -----------------PTTTKSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEP--TP 461

Query: 596  VSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG-SPPVGLIKGEDKDEGPVAEQV 654
             + K  + + KE  P          P++P P  P +   + P        K+  P   + 
Sbjct: 462  TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 521

Query: 655  KKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYI 714
               T   +A          +   + +TP  P P T   P+    T  +    +P+     
Sbjct: 522  PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTTPK--KPA 577

Query: 715  PQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAA 774
            P     PA   P+  P P +   P        A  + P + +        P   +  A  
Sbjct: 578  PTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTPEKLAPT 635

Query: 775  GPPLVAATPYSSYIPYNPQQ----FPGQPAMMQPMAHYPSQPVF-APMLQSNPRMLTSGS 829
             P   A T      P  P++     P +PA   P A  P+ P   AP     P   T   
Sbjct: 636  TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 695

Query: 830  HPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHA 889
                    + P  P    PT      T+ +  P    +    +  P TT   +       
Sbjct: 696  PAPTTPKETAPTTPKGTAPT------TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 749

Query: 890  APSPVQHQAGQAPHLGSGQPQQNLYHPGALT--GTPPSLPPGPSAQSPQSSFPQPAAVYA 947
            AP+  +   G AP             P   T  GT P+    P+  +P+   P+  A   
Sbjct: 750  APTTPK---GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 806

Query: 948  IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPH----------PPQVMLLHPPQSH 997
                + P   T+         +T  T    P P  P           PP    +  P + 
Sbjct: 807  ---TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTT 863

Query: 998  GGPPQ-GAVPQSGVPALSASTPSPYPYIGHPQAPLPP 1033
              P      P    P LSA  P+P      P+ P  P
Sbjct: 864  KEPTTIHKSPDESTPELSAE-PTPKALENSPKEPGVP 899



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 107/502 (21%), Positives = 162/502 (32%), Gaps = 67/502 (13%)

Query: 406 SRMSPKAQRPLRGAKTLSSPSN--RPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCP 463
           ++ +P   +      T S+P+    PS  T+  P P   +   P +PK  AP       P
Sbjct: 527 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 586

Query: 464 EPPIGSAVPTSSASIPVTSSVSDPGV-GSISPASPKISLAPTDVKEL--STKEPGRTLEP 520
             P   A  T+    P T     P      +P +PK  L PT  ++L  +T E      P
Sbjct: 587 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTP 645

Query: 521 QELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFP-------PRILK 573
           +ELA    + P     ++                  +++P    +P P       P   K
Sbjct: 646 EELAPTTPEEPTPTTPEEPAP-----------TTPKAAAPNTPKEPAPTTPKEPAPTTPK 694

Query: 574 EEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG 633
           E      KE      + P G+  ++  E       KP       T   E     C     
Sbjct: 695 EPAPTTPKET---APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 751

Query: 634 SPPVGLIKGEDKDEGPV-----AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPR 688
           + P G      K+  P      A    K T     KE  PT P     K  +  T+ GP 
Sbjct: 752 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP- 810

Query: 689 THSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAK 748
           T +T   P  T  +            P     PA   P+  P P +   P          
Sbjct: 811 TSTTSDKPAPTTPK---------ETAPTTPKEPAPTTPKK-PAPTTPETP---------- 850

Query: 749 GSLPPQRSDQHQPASA--PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMA 806
              PP  S+   P +   P  +  +     P ++A P    +  +P++ PG P    P A
Sbjct: 851 ---PPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE-PGVPTTKTPAA 906

Query: 807 HYPSQPVFAP------MLQSNPRMLTSGSHPQAIVSSSTPQYPSAE--QPTPQALYATVH 858
             P     A        L++ P   T+        +++T +   ++    T Q    T  
Sbjct: 907 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 966

Query: 859 QSYPHHATQLHAHQPQPATTPT 880
            + P   T L      P  T T
Sbjct: 967 DTTPFKITTLKTTTLAPKVTTT 988



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 113/544 (20%), Positives = 176/544 (32%), Gaps = 67/544 (12%)

Query: 381 PRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA 440
           P+ P       P P +        P   +P  + P        +P+       + P  PA
Sbjct: 440 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 499

Query: 441 VGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKIS 500
                 P    +  P+P +   P        PT++ S P T+    P     +P +PK  
Sbjct: 500 PTTPKEPAPTTTKEPSPTTPKEP-------APTTTKSAPTTTKEPAPTTTKSAPTTPK-E 551

Query: 501 LAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPS 557
            +PT  KE    + KEP  T  P++ A    K P     ++       +      K    
Sbjct: 552 PSPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 610

Query: 558 SSPENSLDPFPPRILKEEPK---GKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAP 614
           ++P+ +    P ++    P+       E     T E +      +    + +E  P    
Sbjct: 611 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 670

Query: 615 SGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGP--VAEQVKKSTLNPNAKEFNPTKPL 672
           +     P++P P  P +    P      E     P   A    K T     KE  PT P 
Sbjct: 671 AAAPNTPKEPAPTTPKE----PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 726

Query: 673 LSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP 732
               K  +  T+  P T +T   P                  P    G A   P+  P P
Sbjct: 727 KPAPKELAPTTTKEP-TSTTCDKPA-----------------PTTPKGTAPTTPK-EPAP 767

Query: 733 VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLV---AATPYSSYIP 789
            +   P         KG+ P   +   +PA   P   A     P       +T      P
Sbjct: 768 TTPKEPAP----TTPKGTAP---TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 820

Query: 790 YNPQQ----FPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSS---STPQY 842
             P++     P +PA   P    P+ P   P   S     T+   P  I  S   STP+ 
Sbjct: 821 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 880

Query: 843 PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTG--------SQPQSQHAAPSPV 894
             + +PTP+AL  +  +          A +P+  TT           + P++  AAP   
Sbjct: 881 --SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 938

Query: 895 QHQA 898
           +  A
Sbjct: 939 KETA 942



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 130/637 (20%), Positives = 203/637 (31%), Gaps = 64/637 (10%)

Query: 432  ETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGS 491
            E   P  P   +  PP S  S      +   P+PP          S  +T   S      
Sbjct: 106  EVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQE 165

Query: 492  ISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGA- 550
             S +S   S + T  K  S+K      E Q+  ++         ++   +   + + G+ 
Sbjct: 166  SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSG 225

Query: 551  ----QFKLQP--SSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVS 604
                 FK+    +S+ +++     P+I   +P      +     +    S   +K  +V 
Sbjct: 226  LDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVE 285

Query: 605  DKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAK 664
             KE       +  T+G E+      +Q+      + K   KD  P ++ + K T  P A 
Sbjct: 286  TKETTTTNKQTS-TDGKEKTTSAKETQS------IEKTSAKDLAPTSKVLAKPT--PKA- 335

Query: 665  EFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYIS------------ 712
            E     P L+  K   TPT+P     +TP  P  T  +S   +P+  +            
Sbjct: 336  ETTTKGPALTTPKEP-TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPK 394

Query: 713  -YIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAA 771
               P     PA   P+  P P +   P              P  +   +PA   P   A 
Sbjct: 395  EPAPTTTKEPAPTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP 453

Query: 772  AAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHP 831
                 P    TP +   P    + P      +P    P +P  AP     P   T     
Sbjct: 454  TTPKEP----TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP--APTTPKEPAPTTPKEPA 507

Query: 832  QAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHA----HQPQPATTPTGSQPQSQ 887
                   +P  P    PT      T  +  P   T   A     +P P TT   +    +
Sbjct: 508  PTTTKEPSPTTPKEPAPTTTKSAPTTTKE-PAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 566

Query: 888  HAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGT---PPSLPPGPSAQSPQSSFP-QPA 943
              AP+  +  A   P     +P        A T T    P+ P  P+  +P+ + P  P 
Sbjct: 567  EPAPTTPKKPAPTTPK----EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 622

Query: 944  AVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPP----PHPGAPHPPQVMLLHPPQSHGG 999
             +     ++L          T        T   P    P   AP  P+    + P+    
Sbjct: 623  KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE--- 679

Query: 1000 PPQGAVPQSGVPALSASTP-SPYPYIGHPQAPLPPPG 1035
             P    P+   P    +TP  P P      AP  P G
Sbjct: 680  -PAPTTPKEPAP----TTPKEPAPTTPKETAPTTPKG 711



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 73/315 (23%), Positives = 110/315 (34%), Gaps = 59/315 (18%)

Query: 405  PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464
            P+  +PK   P   A T +     P+  TS  P P   +   P +PK  AP       P 
Sbjct: 789  PAPTTPKKPAPKELAPTTTKG---PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 845

Query: 465  PPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPT-DVKELSTKEPGRTLEPQEL 523
             P      TS  S P T+        S   ++P++S  PT    E S KEPG    P   
Sbjct: 846  TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG---VPTTK 902

Query: 524  ARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEV 583
               A K       + +    +LR           ++PE +     P++ KE     EK  
Sbjct: 903  TPAATKPEMTTTAKDKTTERDLR-----------TTPETT--TAAPKMTKETATTTEKTT 949

Query: 584  DGLLTSEPMGSPVSSKTESVSDKEDKP---------PLAPSGGT-----------EGPEQ 623
            +  +T+       +++  S + ++  P          LAP   T             PE+
Sbjct: 950  ESKITA------TTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEE 1003

Query: 624  PPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP- 682
               P    T S          K   P  ++  K+   P + +   T P +   K+T TP 
Sbjct: 1004 TAKPKDRATNS----------KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPR 1053

Query: 683  --TSPGPRTHSTPSI 695
              TS  P  + T  I
Sbjct: 1054 KMTSTMPELNPTSRI 1068


>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
          Length = 1003

 Score = 70.5 bits (171), Expect = 8e-12
 Identities = 123/486 (25%), Positives = 159/486 (32%), Gaps = 74/486 (15%)

Query: 593  GSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAE 652
            G P S   E  S  +  P LA  GG   P +   P PS   S P  L +G      P   
Sbjct: 159  GGPGSLPPEPPSVSQAFPTLAGPGGLF-PPRLADPVPSGGSSSPRFLPRGNAPSPAPPPP 217

Query: 653  QVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTP-SIPVLTAGQSGLYSPQYI 711
                  ++ NA  +N    L S    +   + P P   S+P S P L      L  P   
Sbjct: 218  PA----ISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPP-- 271

Query: 712  SYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAA 771
              +P  +  PA   P   P PVS++         G  G  P        P  A  ++ AA
Sbjct: 272  --LPPSNNLPAHPGPASQP-PVSSATM-HLPLVLGPLGGAPTVEGPGAPPFLASSLLSAA 327

Query: 772  AAAG-PPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPML----------QS 820
            A A  PPL   +      P          + ++P    P +P     L          +S
Sbjct: 328  AKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRS 387

Query: 821  NPRMLTSGSHPQAIVSSSTPQYPSAEQ----PTPQALYATVHQSYPHHATQLHAHQPQPA 876
             PR       P ++   S P  PS       PTP       H     +     AH P P 
Sbjct: 388  RPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTP----GPSHSDGSFNLLGSDAHLPPPP 443

Query: 877  TTPTGSQPQSQH----------------AAPSPVQHQAGQAPHLGSGQPQQNLYHPGALT 920
            T  +GS PQ +H                   +P    A +AP + S  P       G   
Sbjct: 444  TLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPS--PVLQSPSEGLGM 501

Query: 921  GTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHP 980
            G  P+ P  P A      FP P    A+       GF  M       +  G    PPP P
Sbjct: 502  GAGPACPLPPLAGGEAFPFPSPEQGLALSGA----GFPGMLGALPLPLSLG---QPPPSP 554

Query: 981  ------------GAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQ 1028
                        G   PP   LL PP   G P     P+   P+L  ++  P P    P 
Sbjct: 555  LLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEG--PSLLVASLLPPP----PS 608

Query: 1029 APLPPP 1034
              LPPP
Sbjct: 609  DLLPPP 614



 Score = 67.4 bits (163), Expect = 7e-11
 Identities = 160/722 (22%), Positives = 232/722 (32%), Gaps = 159/722 (22%)

Query: 384  PHHLDNSSPGPGSE--------ARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSV 435
            P      SPGP S            +NGGP  + P+     +   TL+ P        + 
Sbjct: 132  PQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLA- 190

Query: 436  PPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPA 495
             P P+ G   P   P+  AP+P  A  P P I    P+ +    + SS+    +GS  P 
Sbjct: 191  DPVPSGGSSSPRFLPRGNAPSP--APPPPPAISLNAPSYNWGAALRSSLVPSDLGS--PP 246

Query: 496  SPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQ 555
            +P  S +P     L       T  P   +      PG                       
Sbjct: 247  APHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPG----------------------P 284

Query: 556  PSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSP--VSSKTESVSDKEDKPPLA 613
             S  P +S     P +L   P G      G  T E  G+P  ++S   S + K   PPL 
Sbjct: 285  ASQPPVSSATMHLPLVLG--PLG------GAPTVEGPGAPPFLASSLLSAAAKAQHPPLP 336

Query: 614  PSGGTEG----------------------PEQPPPPCPSQTGSPPVGLIKGEDKDEGPV- 650
            P    +G                      P +PP       G  P    +   +   PV 
Sbjct: 337  PPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVP 396

Query: 651  --------AEQVKKSTLN------PNAKEFNPTKPLLSVNKSTSTPTS------PGPRTH 690
                    ++ +  S L+      P     + +  LL  +     P +      P PR  
Sbjct: 397  QPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHP 456

Query: 691  STPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGS 750
              PS+P  T+G         +S +P     PA     + P PV  S     G   G    
Sbjct: 457  IQPSLPGTTSGS--------LSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACP 508

Query: 751  LPPQRSDQHQPASAPPMMQAAAAAG-PPLVAATPYSSYIPYNPQQFPGQPAMMQPM---- 805
            LPP    +  P  +P    A + AG P ++ A P    +P +  Q P  P +   +    
Sbjct: 509  LPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALP----LPLSLGQPPPSPLLNHSLFGVL 564

Query: 806  ----AHYPSQPVFAPMLQSNPRMLTSGSH-PQAIVSSSTPQYPSAEQPTPQALYATVHQS 860
                   P +P+  P     P +       P  +V+S  P  PS   P P A  + +  S
Sbjct: 565  TGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLAS 624

Query: 861  YPHHATQLHAHQPQPATTPT-GSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGAL 919
            +           P  A  PT G    S   A  P            SG+P   L     L
Sbjct: 625  F----------LPLLALGPTAGDGEGSAEGAGGP------------SGEPFSGLGDLSPL 662

Query: 920  TGTPPSLPP----------GPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQ 969
               P S PP            +   P  + PQP  + A      P      + VT A   
Sbjct: 663  LFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSA------PQPGPPTSSVTTATTD 716

Query: 970  TGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQA 1029
             G ++       +  PPQ++          P  GA     + +L+ S+P   P +  P  
Sbjct: 717  PGASSLGKAPSNSGRPPQLL---------SPLLGASLLGDLSSLT-SSPGALPSLLQPPG 766

Query: 1030 PL 1031
            PL
Sbjct: 767  PL 768



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 156/689 (22%), Positives = 213/689 (30%), Gaps = 159/689 (23%)

Query: 359  GPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRG 418
            GP GG       G  P L+S          +    P S  +G         P+AQ P   
Sbjct: 302  GPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQG-------RRPRAQAPSAS 354

Query: 419  AKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASI 478
              +   PS R         PP V R+   R P++   +   A  P P             
Sbjct: 355  HSSSLRPSQRRPRR-----PPTVFRLLEGRGPQTPRRSRPRAPAPVP------------- 396

Query: 479  PVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQK 538
                                        +  S  EP + + P  L+ +    PG  +   
Sbjct: 397  ----------------------------QPFSLPEPSQPILPSVLSLLGLPTPGPSHSDG 428

Query: 539  RFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEP--MGSPV 596
             F L      G+   L P  +  +   P P   ++    G      G L+S P     P 
Sbjct: 429  SFNL-----LGSDAHLPPPPTLSSGSPPQPRHPIQPSLPG---TTSGSLSSVPGAPAPPA 480

Query: 597  SSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKK 656
            +SK   V     + P    G   GP  P PP            + G +    P  EQ   
Sbjct: 481  ASKAPVVPSPVLQSPSEGLGMGAGPACPLPP------------LAGGEAFPFPSPEQ--- 525

Query: 657  STLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQ 716
              L  +   F      L +  S   P       HS     VLT G  G   P+       
Sbjct: 526  -GLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSL--FGVLTGG-GGQPPPE------- 574

Query: 717  IHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGP 776
                P +  P     P++   P  +G        LPP  SD   P SAPP    A+    
Sbjct: 575  ----PLLPPPGGPGPPLAPGEP--EGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFL-- 626

Query: 777  PLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVS 836
            PL+A  P +           G        A  PS   F+ +   +P +    S P  +++
Sbjct: 627  PLLALGPTA-----------GDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIA 675

Query: 837  SSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQH 896
             ++    +   P             P     L A QP P T+   +      A   P   
Sbjct: 676  LNSALLAATLDPP---------SGTPPQPCVLSAPQPGPPTSSVTT------ATTDPGAS 720

Query: 897  QAGQAPHLGSGQPQQNLYHP---GALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQL 953
              G+AP   SG+P Q L  P    +L G   SL   P A       P P     +  Q L
Sbjct: 721  SLGKAPS-NSGRPPQ-LLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSGQLGLQLL 778

Query: 954  PHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLH---PPQSHGGP------PQGA 1004
            P G                  APPP   A  P   +L     PP+    P      P  A
Sbjct: 779  PGG-----------------GAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASA 821

Query: 1005 V-PQSGVPALSASTPSPYPYIGHPQAPLP 1032
            + P+   P LSA  P P+   G P  P+P
Sbjct: 822  LEPEPARPPLSALAP-PH---GSPDPPVP 846



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 59/266 (22%), Positives = 95/266 (35%), Gaps = 59/266 (22%)

Query: 373 RPGLSSLPPRGP--HHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTL---SSPSN 427
           +P + S P  GP    +  ++  PG+ + G     S   P+   PL GA  L   SS ++
Sbjct: 694 QPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTS 753

Query: 428 RPSGETSVPPPPAV---GRMYPPRSPKSAAPAPISASC-------------PEPPIGSAV 471
            P    S+  PP     G++     P   AP P+S +              PE P    +
Sbjct: 754 SPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCL 813

Query: 472 PTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELST-------------------- 511
           P  S   P ++   +P    +S  +P        V EL T                    
Sbjct: 814 PPES---PASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRGRRGGGGLRGING 870

Query: 512 -------KEPGRTLEPQELARIAGKVPGLQNEQKRFQLE--------ELRKFGAQFKLQP 556
                  ++PG   EP  LA   G   G   + +R            EL + GA+ K  P
Sbjct: 871 EARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGGAEPKDPP 930

Query: 557 SSSPENSLDPFPPRILKEEPKGKEKE 582
              P +     PP ++++  +G+ ++
Sbjct: 931 PPGPHSEDLKVPPGVVRKSRRGRRRK 956



 Score = 38.9 bits (89), Expect = 0.026
 Identities = 36/126 (28%), Positives = 41/126 (32%), Gaps = 9/126 (7%)

Query: 4   PQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVA 63
           P PL     P  P            GG  PP    P PL      PGPP A     GP  
Sbjct: 542 PLPLSLGQPPPSPLLNHSLFGVLTGGGGQPP----PEPLLPPPGGPGPPLAPGEPEGPSL 597

Query: 64  AAGSGLRRGAEGILAPQPPPPQQ--HQERPGAA---AIGSARGQSTGKGPPQSPVFEGVY 118
              S L      +L P   PP        P  A     G   G + G G P    F G+ 
Sbjct: 598 LVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLG 657

Query: 119 NNSRML 124
           + S +L
Sbjct: 658 DLSPLL 663



 Score = 37.0 bits (84), Expect = 0.097
 Identities = 40/159 (25%), Positives = 59/159 (37%), Gaps = 21/159 (13%)

Query: 881  GSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFP 940
            G+ PQ  H            +P   S +P   +     L G P SLPP P + S   +FP
Sbjct: 129  GASPQMFHTV----------SPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVS--QAFP 176

Query: 941  QPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGP 1000
              A    +   +L     +    +   +  G   +P P    P PP + L  P  + G  
Sbjct: 177  TLAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAP----PPPPAISLNAPSYNWGAA 232

Query: 1001 PQGAVPQSGV-----PALSASTPSPYPYIGHPQAPLPPP 1034
             + ++  S +     P  S+S PS  P      A  PPP
Sbjct: 233  LRSSLVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPP 271



 Score = 37.0 bits (84), Expect = 0.097
 Identities = 34/115 (29%), Positives = 41/115 (35%), Gaps = 17/115 (14%)

Query: 4   PQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPP------------GP 51
           P P    S P  PP    + A  PP    PP+  LP     ++ PP            GP
Sbjct: 246 PAPHASSSPPSDPPLFHCSDALTPP--PLPPSNNLPAHPGPASQPPVSSATMHLPLVLGP 303

Query: 52  PAAASPCLGPVAA---AGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQS 103
              A    GP A    A S L   A+    P PPP      RP A A  ++   S
Sbjct: 304 LGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSS 358



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 20/56 (35%), Positives = 24/56 (42%), Gaps = 6/56 (10%)

Query: 31  TSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQ 86
           +SP  G  P    T +  PGPP+A  PC  P          G  G L P+PP   Q
Sbjct: 124 SSPGEGASPQMFHTVS--PGPPSARPPCRVPPTTP----LNGGPGSLPPEPPSVSQ 173



 Score = 32.0 bits (71), Expect = 3.1
 Identities = 31/95 (32%), Positives = 35/95 (36%), Gaps = 16/95 (16%)

Query: 11  SQPQQPPPTQQAVARRP-PGGTSP-------PNGG------LPGPLATSAAPPGPPAAAS 56
           S P +PP   QA      PGG  P       P+GG      LP   A S APP PPA + 
Sbjct: 163 SLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAIS- 221

Query: 57  PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERP 91
               P    G+ LR          PP P      P
Sbjct: 222 -LNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPP 255



 Score = 31.6 bits (70), Expect = 4.1
 Identities = 32/117 (27%), Positives = 40/117 (34%), Gaps = 24/117 (20%)

Query: 13  PQQPPPTQQAVARRPPGGT-SPPNGGLPGPLATSAAPPGPP------AAASPCLGPVAAA 65
           P   PPT  A+       T  PP+G  P P   SA  PGPP      A   P    +  A
Sbjct: 666 PLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKA 725

Query: 66  GSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKG------PPQSPVFEG 116
            S   R           PPQ      GA+ +G     ++  G       P  P+  G
Sbjct: 726 PSNSGR-----------PPQLLSPLLGASLLGDLSSLTSSPGALPSLLQPPGPLLSG 771



 Score = 30.8 bits (68), Expect = 7.0
 Identities = 49/206 (23%), Positives = 69/206 (33%), Gaps = 40/206 (19%)

Query: 320 GRTEEEKHSAVQRQGSGRESPSLASREGKYIP--------LPQRVREGPRGGVRCSSSRG 371
           G   + +H  +Q    G  S SL+S  G   P        +P  V + P  G+      G
Sbjct: 448 GSPPQPRHP-IQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGL----GMG 502

Query: 372 GRPGLSSLPPRGPHHLDNSSPGPGSEARG-------------INGGPSRMSPKAQRPLRG 418
             P     P  G       SP  G    G             ++ G    SP     L G
Sbjct: 503 AGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFG 562

Query: 419 AKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASI 478
              L+    +P  E  +PPP   G    P  P+   P+ + AS   PP    +P  SA  
Sbjct: 563 V--LTGGGGQPPPEPLLPPPGGPGPPLAPGEPE--GPSLLVASLLPPPPSDLLPPPSA-- 616

Query: 479 PVTSSVSDPGVGSISPASPKISLAPT 504
                   P    ++   P ++L PT
Sbjct: 617 --------PPSNLLASFLPLLALGPT 634


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 84/348 (24%), Positives = 123/348 (35%), Gaps = 22/348 (6%)

Query: 611  PLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTK 670
            P   S G+ GP  P  P P    SP         +   P     +  + +P +  ++PT 
Sbjct: 1567 PTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTS 1626

Query: 671  PLLSVNKSTSTPTSP--GPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQM 728
            P  S      +PTSP   P + S        +  S  YSP   SY P     P+      
Sbjct: 1627 PSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP---TSPSYSPTSP 1683

Query: 729  YPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPAS------APPMMQAAAAAGPPLVAAT 782
               P S S       Y     S  P  S  + P S      +P     + +  P   + +
Sbjct: 1684 SYSPTSPSYSPTSPSYSPTSPSYSP-TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1742

Query: 783  PYS-SYIPYNPQQFPGQPAMMQPMAHY-PSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
            P S +Y P +P   P  P+       Y P+ P + P   +      S S      S ++P
Sbjct: 1743 PTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSP 1802

Query: 841  QY-PSAEQPTPQALYATVHQSYPHHATQLHAHQP-QPATTPTGSQPQSQHAAPSPVQHQA 898
             Y PS+ + TPQ+   T   S P ++    ++ P  P  TPT   P    ++P       
Sbjct: 1803 SYSPSSPRYTPQS--PTYTPSSPSYSPSSPSYSPTSPKYTPT--SPSYSPSSPEYTPTSP 1858

Query: 899  GQAPHLGSGQPQQNLYHPGALTGTP--PSLPPGPSAQSPQSSFPQPAA 944
              +P      P    Y P + T +P  P   P     SP S    P +
Sbjct: 1859 KYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTS 1906



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 117/476 (24%), Positives = 157/476 (32%), Gaps = 64/476 (13%)

Query: 391  SPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS-------GETSVPPPPAVGR 443
            SP  GS   G+  G +  SP A     G     SP+  P+       G +S   P   G 
Sbjct: 1532 SPSVGS---GMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGA 1588

Query: 444  MYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAP 503
            M P  SP S A  P S     P   S  PTS +  P + S S P   + SP SP  S +P
Sbjct: 1589 MSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYS-PTSPNYSPTSP--SYSP 1645

Query: 504  TDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN- 562
            T      T        P          P                        PS SP + 
Sbjct: 1646 TSPSYSPTSPSYSPTSPSYSPTSPSYSP----------------------TSPSYSPTSP 1683

Query: 563  SLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSS--KTESVSDKEDKPPLAPSGGTEG 620
            S  P  P      P           TS P  SP S      S S     P  +P+  +  
Sbjct: 1684 SYSPTSPSYSPTSPSYSPTSPSYSPTS-PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYS 1742

Query: 621  PEQP--PPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN--PNAKEFNPTKPLLSVN 676
            P  P   P  P+ T + P            P +     ++ N  P +  ++PT P  S  
Sbjct: 1743 PTSPNYSPTSPNYTPTSP---------SYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPT 1793

Query: 677  KSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNS 736
              + +PTSP      +PS P  T  QS  Y+P   SY P     P+         P S S
Sbjct: 1794 SPSYSPTSPS----YSPSSPRYTP-QSPTYTPSSPSYSPS---SPSYSPTSPKYTPTSPS 1845

Query: 737  VPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYS-SYIPYNPQQF 795
                  +Y        P  S ++ P S P     +    P     +P S +Y P +P   
Sbjct: 1846 YSPSSPEYTPTSPKYSP-TSPKYSPTS-PKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYT 1903

Query: 796  PGQPAMMQPMAHY-PSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTP 850
            P  P        Y P+ P ++P   +       GS         +P  P+    +P
Sbjct: 1904 PTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSPTYSLTSP 1959



 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 87/358 (24%), Positives = 121/358 (33%), Gaps = 31/358 (8%)

Query: 338  ESPSLASREGKYIPL-----PQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNS-S 391
            +SPS +     Y P      P      P       +S    P   S  P  P +   S S
Sbjct: 1611 QSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS 1670

Query: 392  PGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPK 451
              P S +          +  +  P   + + +SPS  P+  +  P  P+     P  SP 
Sbjct: 1671 YSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT 1730

Query: 452  SAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELST 511
            S + +P S S   P   +  PTS    P + S S P   S SP SP  +  PT      T
Sbjct: 1731 SPSYSPTSPSY-SPTSPNYSPTSPNYTPTSPSYS-PTSPSYSPTSPNYT--PTSPNYSPT 1786

Query: 512  KEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRI 571
                    P      +   P       R+  +      +     PSS    S  P  P+ 
Sbjct: 1787 SPSYSPTSPS----YSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSP---SYSPTSPKY 1839

Query: 572  LKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQ 631
                P       +   TS P  SP S K    S     P  +P+  T  P  P     S 
Sbjct: 1840 TPTSPSYSPSSPEYTPTS-PKYSPTSPKYSPTS-----PKYSPTSPTYSPTTPKYSPTSP 1893

Query: 632  TGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNK---STSTPTSPG 686
            T SP   +         P +      T +P + +++PT P  S      ST +PTSPG
Sbjct: 1894 TYSPTSPVYTPTSPKYSPTSP-----TYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPG 1946



 Score = 40.4 bits (93), Expect = 0.009
 Identities = 72/324 (22%), Positives = 103/324 (31%), Gaps = 17/324 (5%)

Query: 339  SPSLASREGKYIPL-----PQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNS-SP 392
            SPS +     Y P      P      P       +S    P   S  P  P +   S S 
Sbjct: 1647 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY 1706

Query: 393  GPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKS 452
             P S +          +  +  P   + + +SPS  P+     P  P      P  SP S
Sbjct: 1707 SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTS 1766

Query: 453  AAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKIS-LAPTDVKELST 511
             + +P S +   P   +  PTS +  P + S S P   S SP+SP+ +  +PT      +
Sbjct: 1767 PSYSPTSPNYT-PTSPNYSPTSPSYSPTSPSYS-PTSPSYSPSSPRYTPQSPTYTPSSPS 1824

Query: 512  KEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDP-FPPR 570
              P          +     P        +     +      K  P+S   +   P + P 
Sbjct: 1825 YSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPT 1884

Query: 571  ILKEEPKGKEKEVDGLL--TSEPMGSPVSSKTESVSDKEDKP-----PLAPSGGTEGPEQ 623
              K  P          +   + P  SP S      S K         P +P G T  P  
Sbjct: 1885 TPKYSPTSPTYSPTSPVYTPTSPKYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTS 1944

Query: 624  PPPPCPSQTGSPPVGLIKGEDKDE 647
            P     S T S     I  +D DE
Sbjct: 1945 PGYSPTSPTYSLTSPAISPDDSDE 1968



 Score = 33.9 bits (76), Expect = 0.82
 Identities = 52/261 (19%), Positives = 90/261 (34%), Gaps = 22/261 (8%)

Query: 776  PPLVAATPYSSYIPYNPQQFPGQPAMMQP--MAHYPSQPVFAPMLQSNPRMLTSGSHPQA 833
            P L AA P   +    P    G    M P      P+   ++P + S      +G  P A
Sbjct: 1491 PGLGAAGPTGMFFGSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSA 1550

Query: 834  IVSSS------------TPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTG 881
               +S            TP  P +  P+   + +      P ++    A++P+   +P G
Sbjct: 1551 ASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPR---SPGG 1607

Query: 882  SQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQ 941
              PQS   +P+   + +  +P      P  +   P     +P   P  PS      S+  
Sbjct: 1608 YTPQSPSYSPTSPSY-SPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP 1666

Query: 942  PAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPP 1001
             +  Y+           + +  + ++  T  + +P     +P  P      P  S   P 
Sbjct: 1667 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPS 1726

Query: 1002 QGAVPQSGVPALSASTPSPYP 1022
                P S  P+ S ++PS  P
Sbjct: 1727 YS--PTS--PSYSPTSPSYSP 1743


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.128    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,508,643
Number of Sequences: 37866
Number of extensions: 4436716
Number of successful extensions: 52207
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 374
Number of HSP's successfully gapped in prelim test: 2385
Number of HSP's that attempted gapping in prelim test: 22566
Number of HSP's gapped (non-prelim): 22320
length of query: 1044
length of database: 18,247,518
effective HSP length: 112
effective length of query: 932
effective length of database: 14,006,526
effective search space: 13054082232
effective search space used: 13054082232
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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