BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|27262647 ataxin 2 related protein isoform A [Homo sapiens] (1075 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|27262647 ataxin 2 related protein isoform A [Homo sapiens] 2210 0.0 gi|27262645 ataxin 2 related protein isoform B [Homo sapiens] 2151 0.0 gi|27262649 ataxin 2 related protein isoform C [Homo sapiens] 2151 0.0 gi|27262653 ataxin 2 related protein isoform E [Homo sapiens] 2113 0.0 gi|27262651 ataxin 2 related protein isoform D [Homo sapiens] 2112 0.0 gi|171543895 ataxin 2 [Homo sapiens] 610 e-174 gi|163965366 nascent polypeptide-associated complex alpha subuni... 104 5e-22 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 97 6e-20 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 97 8e-20 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 93 2e-18 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 87 6e-17 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 82 4e-15 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 82 4e-15 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 80 1e-14 gi|150170670 piccolo isoform 2 [Homo sapiens] 80 1e-14 gi|150378539 piccolo isoform 1 [Homo sapiens] 80 1e-14 gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 79 2e-14 gi|55750053 atrophin-1 [Homo sapiens] 77 9e-14 gi|55750041 atrophin-1 [Homo sapiens] 77 9e-14 gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 74 7e-13 gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 73 1e-12 gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 73 1e-12 gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 72 3e-12 gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 72 4e-12 gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 72 4e-12 gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 72 4e-12 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 71 6e-12 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 71 6e-12 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 71 6e-12 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 71 6e-12 >gi|27262647 ataxin 2 related protein isoform A [Homo sapiens] Length = 1075 Score = 2210 bits (5726), Expect = 0.0 Identities = 1075/1075 (100%), Positives = 1075/1075 (100%) Query: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG Sbjct: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN Sbjct: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120 Query: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV Sbjct: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180 Query: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD Sbjct: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240 Query: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA Sbjct: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300 Query: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP Sbjct: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360 Query: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK Sbjct: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420 Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV Sbjct: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480 Query: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF Sbjct: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540 Query: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT Sbjct: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600 Query: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN Sbjct: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660 Query: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG Sbjct: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720 Query: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA Sbjct: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780 Query: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP Sbjct: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840 Query: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ Sbjct: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900 Query: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM Sbjct: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960 Query: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP Sbjct: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020 Query: 1021 YPYIGHPQGEQPGQAPGFPGGADDRIREFSLAGGIWHGRAEGLQVGQDARVLGGE 1075 YPYIGHPQGEQPGQAPGFPGGADDRIREFSLAGGIWHGRAEGLQVGQDARVLGGE Sbjct: 1021 YPYIGHPQGEQPGQAPGFPGGADDRIREFSLAGGIWHGRAEGLQVGQDARVLGGE 1075 >gi|27262645 ataxin 2 related protein isoform B [Homo sapiens] Length = 1062 Score = 2151 bits (5573), Expect = 0.0 Identities = 1046/1046 (100%), Positives = 1046/1046 (100%) Query: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG Sbjct: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN Sbjct: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120 Query: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV Sbjct: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180 Query: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD Sbjct: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240 Query: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA Sbjct: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300 Query: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP Sbjct: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360 Query: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK Sbjct: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420 Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV Sbjct: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480 Query: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF Sbjct: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540 Query: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT Sbjct: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600 Query: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN Sbjct: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660 Query: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG Sbjct: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720 Query: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA Sbjct: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780 Query: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP Sbjct: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840 Query: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ Sbjct: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900 Query: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM Sbjct: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960 Query: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP Sbjct: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020 Query: 1021 YPYIGHPQGEQPGQAPGFPGGADDRI 1046 YPYIGHPQGEQPGQAPGFPGGADDRI Sbjct: 1021 YPYIGHPQGEQPGQAPGFPGGADDRI 1046 Score = 38.1 bits (87), Expect = 0.045 Identities = 24/76 (31%), Positives = 29/76 (38%), Gaps = 2/76 (2%) Query: 10 PSQPQQPPPTQQAVARRPPGGTSPPNGGLP--GPLATSAAPPGPPAAASPCLGPVAAAGS 67 P P P P Q + P PP G +P G A SA+ P P G Sbjct: 977 PPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAP 1036 Query: 68 GLRRGAEGILAPQPPP 83 G GA+ + P PPP Sbjct: 1037 GFPGGADDRIPPLPPP 1052 >gi|27262649 ataxin 2 related protein isoform C [Homo sapiens] Length = 1097 Score = 2151 bits (5573), Expect = 0.0 Identities = 1046/1046 (100%), Positives = 1046/1046 (100%) Query: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG Sbjct: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN Sbjct: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120 Query: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV Sbjct: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180 Query: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD Sbjct: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240 Query: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA Sbjct: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300 Query: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP Sbjct: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360 Query: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK Sbjct: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420 Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV Sbjct: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480 Query: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF Sbjct: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540 Query: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT Sbjct: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600 Query: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN Sbjct: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660 Query: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG Sbjct: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720 Query: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA Sbjct: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780 Query: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP Sbjct: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840 Query: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ Sbjct: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900 Query: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM Sbjct: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960 Query: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP Sbjct: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020 Query: 1021 YPYIGHPQGEQPGQAPGFPGGADDRI 1046 YPYIGHPQGEQPGQAPGFPGGADDRI Sbjct: 1021 YPYIGHPQGEQPGQAPGFPGGADDRI 1046 >gi|27262653 ataxin 2 related protein isoform E [Homo sapiens] Length = 1044 Score = 2113 bits (5476), Expect = 0.0 Identities = 1029/1032 (99%), Positives = 1029/1032 (99%) Query: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG Sbjct: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN Sbjct: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120 Query: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV Sbjct: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180 Query: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD Sbjct: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240 Query: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA Sbjct: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300 Query: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP Sbjct: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360 Query: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK Sbjct: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420 Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV Sbjct: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480 Query: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF Sbjct: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540 Query: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT Sbjct: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600 Query: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN Sbjct: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660 Query: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG Sbjct: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720 Query: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA Sbjct: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780 Query: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP Sbjct: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840 Query: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ Sbjct: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900 Query: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM Sbjct: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960 Query: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP Sbjct: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020 Query: 1021 YPYIGHPQGEQP 1032 YPYIGHPQ P Sbjct: 1021 YPYIGHPQAPLP 1032 >gi|27262651 ataxin 2 related protein isoform D [Homo sapiens] Length = 1044 Score = 2112 bits (5473), Expect = 0.0 Identities = 1032/1043 (98%), Positives = 1032/1043 (98%), Gaps = 2/1043 (0%) Query: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG Sbjct: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN Sbjct: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120 Query: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV Sbjct: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180 Query: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD Sbjct: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240 Query: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA Sbjct: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300 Query: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP Sbjct: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360 Query: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK Sbjct: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420 Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV Sbjct: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480 Query: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF Sbjct: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540 Query: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT Sbjct: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600 Query: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN Sbjct: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660 Query: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG Sbjct: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720 Query: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA Sbjct: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780 Query: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP Sbjct: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840 Query: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ Sbjct: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900 Query: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM Sbjct: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960 Query: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP Sbjct: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020 Query: 1021 YPYIGHP--QGEQPGQAPGFPGG 1041 YPYIGHP Q Q P P G Sbjct: 1021 YPYIGHPQVQSHPSQQLPFHPPG 1043 >gi|171543895 ataxin 2 [Homo sapiens] Length = 1313 Score = 610 bits (1574), Expect = e-174 Identities = 455/1196 (38%), Positives = 613/1196 (51%), Gaps = 225/1196 (18%) Query: 2 LKPQPLQQPSQPQQPPPTQQAVARR--PPGGTSPPNGGLPGPLATSAAPPGPPAAASPCL 59 LKPQ QQ Q QQ QQ ++ PP + G G LA+ AA P P ++S Sbjct: 163 LKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSP--SSSSVS 220 Query: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPV-FEGVY 118 A A S + G P G RG+++ KG PQS + F+G+Y Sbjct: 221 SSSATAPSSVVAATSGGGRP-----------------GLGRGRNSNKGLPQSTISFDGIY 263 Query: 119 NNSRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRRED 178 N RM+H LT+VVGS C+V+VKNG YEG+FKT S K +L +DA H K++E + GP+RE+ Sbjct: 264 ANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREE 323 Query: 179 IVDTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGD--S 236 I+++++FK SD ++V F+++D +YA +D FTDSAI+ +KVNGEHKEK L+ W+ G+ + Sbjct: 324 IMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAIS--AKVNGEHKEKDLEPWDAGELTA 381 Query: 237 NSDDYDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRA 296 N + LE+D+SNGWDPN+MF++NEENYGV +TYDSSLSSYTVPLE+DNSEEF +RE RA Sbjct: 382 NEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARA 441 Query: 297 AQLAREIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRV 356 QLA EIESS QY+ R+A+ENDD R+EEEK++AVQR S RE S+ +RE KYIP QR Sbjct: 442 NQLAEEIESSAQYKARVALENDD-RSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQRN 500 Query: 357 REG-PRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGG---PSRM-SPK 411 RE G R +S R G+PG S+P R H + +P GS+ R +NGG PS SP Sbjct: 501 REVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPS 560 Query: 412 AQRPLR----------GAKTLSSPSNRPSGETSVPP---------------PPAVGRMYP 446 ++ P R A T + P +RP S PP P + P Sbjct: 561 SRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGP 620 Query: 447 PR-SPK----------SAAPAPISASCP----EPPIGSAVPTSSASIPVTSSVSD--PGV 489 PR SPK SA IS+ PP +A P + + P + S GV Sbjct: 621 PRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGV 680 Query: 490 GSISP----------------------ASPKISLAPTDVKELSTKEPGRTLEPQELARIA 527 +SP ASP+ + PT+ ++ P + P A Sbjct: 681 PRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEA--VAMPIPAASPTPASPASNR 738 Query: 528 GKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN-SLDPFPPRILKEEPKG-------K 579 P + + R Q Q + P+ + EN + P K E KG Sbjct: 739 AVTPSSEAKDSRLQ--------DQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEH 790 Query: 580 EKEVDGL------------LTSEPMGSPVSSKTE-------------------------- 601 K++D L TSE M ++ E Sbjct: 791 RKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSS 850 Query: 602 ---SVSDKEDKPPLAPSGGTEGPEQPPPPCPS---QTGSPPVGLIKGEDKDEGPVAEQVK 655 S S K + P ++PS + + P S QT SP K + +++ AEQV+ Sbjct: 851 NCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVR 910 Query: 656 KSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSI-----PVLTAGQSGLYSPQY 710 KSTLNPNAKEFNP S K ++TPTSP P+ +PS+ P Q ++P Sbjct: 911 KSTLNPNAKEFNPRS--FSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNM 968 Query: 711 ISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQA 770 + +P + P VQ +YP P++ +P Q K A ++P QR DQH ++ MM Sbjct: 969 MYPVP---VSPGVQ--PLYPIPMT-PMPVNQAKTYRAVPNMPQQRQDQHHQSA---MMHP 1019 Query: 771 AAAAGPPLVAATP-YSS-YIPYNPQQFPGQPAMMQPMAHYPSQ--PVFAPMLQSNPRMLT 826 A+AAGPP+ A P YS+ Y+ Y+PQQFP QP ++Q + HY SQ V++P++Q N RM+ Sbjct: 1020 ASAAGPPIAATPPAYSTQYVAYSPQQFPNQP-LVQHVPHYQSQHPHVYSPVIQGNARMMA 1078 Query: 827 SGSHPQ-AIVSSSTPQYPSAEQPTPQALYA---------------------TVHQSYPHH 864 +H Q +VSSS QY + EQ A+YA ++ Q Y H Sbjct: 1079 PPTHAQPGLVSSSATQYGAHEQ--THAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHP 1136 Query: 865 ATQLHAH--QPQPATTPTGSQPQSQHA----APSPV---QHQAGQAPHLGSGQPQQNLYH 915 LH H PQP+ TPTG Q QSQH APSPV QHQA QA HL S Q Q +YH Sbjct: 1137 NATLHPHTPHPQPSATPTGQQ-QSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYH 1195 Query: 916 PGALTGTPPSLPPGPSAQSPQSSFP-QPAAVYAIHHQQLPHGFTN---MAHVTQAHVQTG 971 G L TPPS+ P + QSPQ+SFP V+ IH + +TN MAHV QAHVQ+G Sbjct: 1196 AG-LAPTPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSG 1254 Query: 972 ITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHP 1027 + P HP A P +M PP G PQ A+ QS + + ST + +PY+ HP Sbjct: 1255 MV---PSHPTAHAPMMLMTTQPP----GGPQAALAQSALQPIPVSTTAHFPYMTHP 1303 Score = 39.3 bits (90), Expect = 0.020 Identities = 37/134 (27%), Positives = 52/134 (38%), Gaps = 10/134 (7%) Query: 362 GGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKT 421 G + +R G + PPR L +PG A GP MS K Q+ + + Sbjct: 115 GAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQ 174 Query: 422 LSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIP-- 479 + + PPP A P S A+PA + P S+V +SSA+ P Sbjct: 175 QQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPS-----PSSSSVSSSSATAPSS 229 Query: 480 ---VTSSVSDPGVG 490 TS PG+G Sbjct: 230 VVAATSGGGRPGLG 243 Score = 35.4 bits (80), Expect = 0.29 Identities = 45/155 (29%), Positives = 57/155 (36%), Gaps = 14/155 (9%) Query: 343 ASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPR-GPHHLDNSSPGPGSEARGI 401 A+R + L + R RGG ++ G P + PP GP SSP S+ G Sbjct: 22 AARWPGWRSLQRPARRSGRGGG--GAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGS 79 Query: 402 NGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVP--PPPAVGRMYPPRSPKSAAPAPIS 459 NG R L G L P RP +P P A PP +P A+P Sbjct: 80 NGNGGGAFRPGSRRLLG---LGGPP-RPFVVLLLPLASPGA-----PPAAPTRASPLGAR 130 Query: 460 ASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISP 494 AS P + A P P V P S+ P Sbjct: 131 ASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKP 165 Score = 33.9 bits (76), Expect = 0.85 Identities = 34/110 (30%), Positives = 40/110 (36%), Gaps = 20/110 (18%) Query: 21 QAVARRPPGGTSPPNGGLPGPLATSA-APPGP---------PAAASPCLGPVAAAGSGLR 70 Q ARR G G PGP ++A PPGP P +AS C G G R Sbjct: 32 QRPARRSGRGGG---GAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFR 88 Query: 71 RGAEGILAPQPPPPQ-----QHQERPGAAAIGSARGQSTG--KGPPQSPV 113 G+ +L PP PGA R G PP+S V Sbjct: 89 PGSRRLLGLGGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGV 138 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 104 bits (259), Expect = 5e-22 Identities = 177/750 (23%), Positives = 250/750 (33%), Gaps = 119/750 (15%) Query: 345 REGKYIPLPQRVREGPRGGVRCSSSRGGR--PGLSSLPPRGPHHLDNSSPGPGSEARGIN 402 +EG P P ++ P + SS + R P +P P +P P + Sbjct: 897 KEGPATPAP---KQAPALSMTSSSPKKARATPAPKGIPA-SPSPKGAPTP-PAATPPSPK 951 Query: 403 GGPSRMSPK-------AQRPL-RGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAA 454 GGP+ SPK A P +G SP P+ + PP P G P SPK A Sbjct: 952 GGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATP--SPK-GA 1008 Query: 455 PAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEP 514 P P + + P P S A+ P S P + +P SPK S A T + + + P Sbjct: 1009 PTPPAVTPPSP------KGSPAATPFPKGASTP--PAATPPSPKGSPAATPLPKGAPTTP 1060 Query: 515 GRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLD---PFPPRI 571 TL + + G A P P P PP Sbjct: 1061 AATLPSPKGGPATPSLKGAPTPP------------AATPPSPKGGPATPSPKGAPMPPAA 1108 Query: 572 LKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQ 631 PKG GL T G+P + S K P G P PP Sbjct: 1109 TPPSPKG------GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1162 Query: 632 TGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHS 691 +PP KG K P+ K PT P + +P P+ Sbjct: 1163 LATPPP---KGAPTTPAATPPSPKGGLATPSPKG-APTTPAATPPSPKGGLATPSPKGAP 1218 Query: 692 TPSIPVLTAGQSGLYSPQ-------YISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKY 744 T + + GL +P + P GPA P+ P P + + P +G Sbjct: 1219 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGL 1278 Query: 745 RGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQP 804 + PP + + PP + A PP A TP ++ P +P+ PG P P Sbjct: 1279 -----ATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAA-TPPSPKGSPGTP----P 1328 Query: 805 MAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHH 864 P+ P P L + + P + +TP S E PTP A + P H Sbjct: 1329 PKGAPTPPAVTPPSPKGTPTLPA-TTPSSKGGPTTPS--SKEGPTPPA-------ATPSH 1378 Query: 865 ATQLHAHQPQPATTPTGSQPQSQHAAP-----SPVQHQAGQAPHLGSGQPQQNLYHPGAL 919 P P P P+ +P SP + A G+ P + P A+ Sbjct: 1379 KGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAV 1438 Query: 920 TGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPH 979 TP SL P+ +P+ PA + LP A Q +++P Sbjct: 1439 --TPVSLKKAPATSAPKGG---PATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKA 1493 Query: 980 P------GAPHPPQVMLLHP------PQSHGGP------------PQGAVPQSGV--PAL 1013 P GAP P V+ P P S P P P+ + PA+ Sbjct: 1494 PATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAM 1553 Query: 1014 SASTPSPYPYIGHPQGEQPGQAPGFPGGAD 1043 + +P P I P+ +AP P + Sbjct: 1554 TVPSPKKTPAIPTPK-----EAPATPSSKE 1578 Score = 97.1 bits (240), Expect = 8e-20 Identities = 167/724 (23%), Positives = 225/724 (31%), Gaps = 161/724 (22%) Query: 375 GLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMS----PKAQRPLRGAK----TLSSPS 426 G+S P S GP + ++ S + P+ +G+K T SP+ Sbjct: 798 GVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPT 857 Query: 427 NRPSGETSVPPPPAVGRMYPP--RSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSV 484 P P P AV + P P P P + P P G A P + ++ + Sbjct: 858 --PPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTS 915 Query: 485 SDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEE 544 S P +PA I +P+ K T P+ Sbjct: 916 SSPKKARATPAPKGIPASPSP-KGAPTPPAATPPSPK----------------------- 951 Query: 545 LRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVS 604 ++P P PP PKG G T P G+P S Sbjct: 952 ----------GGPATPSPKWAPTPPAATPPSPKG------GPATPSPKGAPTPPAATPPS 995 Query: 605 DKEDKPPLAPSGGTEGPEQPPPPCPSQTGSP-PVGLIKGEDKDEGPVAEQVKKSTLNPNA 663 K +P G P P PS GSP KG K S Sbjct: 996 PKGGPATPSPKGAPTPPAVTP---PSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPL 1052 Query: 664 KEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAV 723 + PT P ++ P +P + TP P T P GPA Sbjct: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAPTP--PAATP--------------PSPKGGPAT 1096 Query: 724 QAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAAT- 782 +P+ P P + + P +G + PP + PA+ PP + A PP A T Sbjct: 1097 PSPKGAPMPPAATPPSPKGGL-----ATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTT 1151 Query: 783 -------PYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPR--MLTSGSHPQA 833 P P+ P PA P P + P + P T S Sbjct: 1152 PAATPPSPKGGLATPPPKGAPTTPAATPPS---PKGGLATPSPKGAPTTPAATPPSPKGG 1208 Query: 834 IVSSS---TPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQ-----PATTPTGSQPQ 885 + + S P P+A P+P+ AT P A A P PAT P P Sbjct: 1209 LATPSPKGAPTTPAATPPSPKGGLAT---PSPKGAPTTPAATPPSPKGGPATPPPKGAPT 1265 Query: 886 SQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAV 945 A P ++ PH G+ P TPPS GP+ P+ + PAA Sbjct: 1266 PPAATPPSLKGGLATPPHKGA---------PNPAVVTPPSPKGGPATSPPKGAPTPPAAT 1316 Query: 946 YAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHP----------PQ 995 P G + PP GAP PP V P P Sbjct: 1317 -----PPSPKG----------------SPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPS 1355 Query: 996 SHGGP----------PQGAVP-QSGVPALSASTPSPYPYIGHPQGE---------QPGQA 1035 S GGP P A P G PA++ +P P I P+G+ P +A Sbjct: 1356 SKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKA 1415 Query: 1036 PGFP 1039 P P Sbjct: 1416 PATP 1419 Score = 97.1 bits (240), Expect = 8e-20 Identities = 188/775 (24%), Positives = 259/775 (33%), Gaps = 119/775 (15%) Query: 335 SGRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGR--PGLSSLPPRG-----PHHL 387 S + P+ S +G P P P+GG S +G P ++ P+G P Sbjct: 972 SPKGGPATPSPKGAPTP-PAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPK 1030 Query: 388 DNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGET--SVPPPPAVGRMY 445 S+P P + G P+ P A TL SP P+ + P PPA Sbjct: 1031 GASTP-PAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAA---- 1085 Query: 446 PPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTD 505 P SPK P P PP + P+ + P + +P SPK LA Sbjct: 1086 TPPSPKGGPATPSPKGAPMPPAATP-PSPKGGLATPPHKGAPTTPAATPPSPKGGLATPP 1144 Query: 506 VKELSTKEPGRTLEPQE-LA----RIAGKVPGLQNEQKRFQLEELRKFGAQFK---LQPS 557 K T P+ LA + A P + L GA PS Sbjct: 1145 PKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1204 Query: 558 -----SSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPL 612 ++P P P PKG GL T P G+P + S K Sbjct: 1205 PKGGLATPSPKGAPTTPAATPPSPKG------GLATPSPKGAPTTPAATPPSPKGGPATP 1258 Query: 613 APSGGTEGPEQPPPPC------PSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEF 666 P G P PP P G+P ++ GP K + P A Sbjct: 1259 PPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPP 1318 Query: 667 NP-------------TKPLLSVNKSTSTPTSP--------GPRTHST---PSIPVLTAGQ 702 +P T P ++ TPT P GP T S+ P+ P T Sbjct: 1319 SPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSH 1378 Query: 703 SGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGA-----KGSLPPQRSD 757 G P P+ GPA+ +P+ P S +V K A +G+ P + D Sbjct: 1379 KG--GPAMTPPSPK--RGPAIPSPK--GDPTSPAVIPLSPKKAPATPVTREGAATPSKGD 1432 Query: 758 QHQPASAPPMMQAAAAAGPPLVA-ATPYSSYIPYNPQQFPGQPAMMQPMAHYP----SQP 812 PA P ++ A A P ATP S P P P P+ +P A S P Sbjct: 1433 LTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTP--PSPKEPPAPKQVATSSSP 1490 Query: 813 VFAPMLQSNPRMLTSGSHPQAIVSS--STPQYPSAEQPTPQALYATVHQSYPHHATQLHA 870 AP + P + + + P I SS P PS+ + + + P A Sbjct: 1491 KKAP---ATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEA 1547 Query: 871 HQPQPATTP----TGSQPQSQHAAPSPVQHQAGQAP------HLGSGQPQQNLYHPGALT 920 P T P T + P + A +P +A P + G+ P++ L P A+T Sbjct: 1548 LIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPP-AVT 1606 Query: 921 GTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHP 980 P P P A +P S PA P G VT + ++ T+ Sbjct: 1607 SPSPKEAPTPPAVTPPSPEKGPAT-------PAPKGTPTSPPVTPSSLKDSPTS------ 1653 Query: 981 GAPHPPQV---MLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQP 1032 P V M PQ+ G P P + L A P P I P + P Sbjct: 1654 ----PASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGP 1704 Score = 80.9 bits (198), Expect = 6e-15 Identities = 157/688 (22%), Positives = 225/688 (32%), Gaps = 111/688 (16%) Query: 417 RGAKTLSSPSNRPSGETSVPPPPAVG---RMYPPRSPKSAAPAPISASCPEPPIGS---- 469 +G T+SS + PSG +V ++ + SP + P+ A P +G+ Sbjct: 383 KGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLV 442 Query: 470 --------AVPTSSASIP--VTSSVSDPGVGSISPASPK-ISLAPTDVKELSTKEPGRTL 518 A PT++ + V+ +S + +I P SP + +AP KE ST + TL Sbjct: 443 VTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPST-QVATTL 501 Query: 519 ---------EPQELARIAGKVPGLQNEQKRFQLEELRKFGAQF---------KLQPS--- 557 +P++L + V QK Q GA F K P+ Sbjct: 502 RIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLP 561 Query: 558 ---SSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPM--GSPVSSKTESVSDKEDKPPL 612 ++P+NS E P E + EP+ G P SS T + + Sbjct: 562 LVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLG-VNSSASV 620 Query: 613 APSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTL------------- 659 + GP+ P S +P V E D VA K T Sbjct: 621 IKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGT 680 Query: 660 ------NPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISY 713 N KE T L S + P +P P+ P ++ A P+ Sbjct: 681 VSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLA-------PEIPKS 733 Query: 714 IPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAA 773 +P + PA P S + P + S AS+ + A Sbjct: 734 VPSPSLPPAGTPPGTKKVD-GISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLAD 792 Query: 774 AGPPL-VAATPYSSYIPYNPQQFPGQPAMMQPMAHY--PSQPVFAPMLQSNPRMLTSGSH 830 + PL V+ +P + P G P+ + P PV A L N Sbjct: 793 SPSPLGVSVSPQTK----RPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKD 848 Query: 831 PQAIVSSSTPQYPSAEQPTPQALY-----------------ATVHQSYPHHATQLHAHQP 873 A S TP P PTP A+ + V+ +P A + Sbjct: 849 SPATTHSPTPPSPKGA-PTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQ 907 Query: 874 QPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTP-PSLPPGPSA 932 PA + T S P+ A P+P A +P P P TP P P P A Sbjct: 908 APALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPA 967 Query: 933 QSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLH 992 +P S PA P G T + G A P GAP PP V Sbjct: 968 ATPPSPKGGPAT-------PSPKGAPTPPAATPPSPKGG--PATPSPKGAPTPPAVT--- 1015 Query: 993 PPQSHGGPPQGAVPQSGVPALSASTPSP 1020 PP G P P+ +A+ PSP Sbjct: 1016 PPSPKGSPAATPFPKGASTPPAATPPSP 1043 Score = 41.2 bits (95), Expect = 0.005 Identities = 78/327 (23%), Positives = 115/327 (35%), Gaps = 63/327 (19%) Query: 381 PRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA 440 P P + SSP P G PS PK + + A T SP P+ PP P Sbjct: 1571 PATPSSKEASSP-PAVTPSTYKGAPS---PK-ELLIPPAVTSPSPKEAPTPPAVTPPSPE 1625 Query: 441 VGRMYP---------PRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGS 491 G P P +P S +P S + +G+ VP +S +P + Sbjct: 1626 KGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVL 1685 Query: 492 ISPA--SPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFG 549 ++PA S I APT K TK+ T P P +N K Sbjct: 1686 VAPAPESTPIITAPTR-KGPQTKKSSATSPP------ICPDPSAKNGSK----------- 1727 Query: 550 AQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDK 609 P +++ P P ++++ K D + + +P SK + Sbjct: 1728 ---------GPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKAST------- 1771 Query: 610 PPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPT 669 PL + + +P S SPPV L P+A + P ++F P+ Sbjct: 1772 -PLTAAAFEKVLPKPESASVSAAPSPPVSL---------PLAPSPVPTL--PPKQQFLPS 1819 Query: 670 KPLLSVNKSTSTPTSPGPRTHSTPSIP 696 P L V +S S P +P P IP Sbjct: 1820 SPGL-VLESPSKPLAPADEDELLPLIP 1845 Score = 40.0 bits (92), Expect = 0.012 Identities = 136/646 (21%), Positives = 210/646 (32%), Gaps = 101/646 (15%) Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPP----------PAVGRMYPPRSPKSAA 454 P + A P+ A ++++ +P ++PPP A + P SP + A Sbjct: 17 PQPQAETAVLPMSSALSVTAALGQPG--PTLPPPCSPAPQQCPLSAANQASPFPSPSTIA 74 Query: 455 PAPISASCPEPPIGSAVPTSSAS--------------IPVTSSVSDP-------GVGSIS 493 P+ P+ G+A+P +A P +++ P G S S Sbjct: 75 STPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSS 134 Query: 494 PASPKISLAPTDVKELSTKEPGRTLEPQELA------RIAGKVPGLQNEQKRFQLEELRK 547 ++LAP V++ S P P +A I P +E K L K Sbjct: 135 APLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPK----TNLNK 190 Query: 548 FGAQFKLQPSSSPENSLDPFPPRILKEEP---KGKEKEVDGLLTSEPMGSPVSS------ 598 ++ P +P PP I+ P + + S P +P ++ Sbjct: 191 VPSEVVPNPKGTPS------PPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASP 244 Query: 599 --KTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKK 656 K ++S P S +GP PP T S PV + K GP Sbjct: 245 QVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPV--VTSSQKTAGPNTPPDFP 302 Query: 657 STLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQS--GLYSPQYISYI 714 +L + + S S GP S P++ ++ S G P S I Sbjct: 303 ISLGSHLAPLHQ-----SSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVI 357 Query: 715 PQI----HMGPAVQAPQMYPYPVSNSVPGQQGKYR-GAKGSLPPQRSDQHQPASAPPMMQ 769 P + + PA A P + P GSL S P ++ + Sbjct: 358 PPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKS 417 Query: 770 AA-AAAGPPLVAATPYSS-----YIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPR 823 + A PLVA P SS + NP P +A S P + S P Sbjct: 418 SPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPP-----MSSGPI 472 Query: 824 MLTSGSHPQAIVSSS-TPQYPSAEQPTPQALYATVHQSYPHHATQLHAH--QPQPATTPT 880 + P A+V + P+ PS + T + + P L + P Sbjct: 473 SNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDL 532 Query: 881 GSQPQSQHAAP-SPVQHQAGQAPH-------LGSGQPQQNLYHPGALTGTPPSLPPGPSA 932 + P S AP SP QAG L P+ + T + P +P P A Sbjct: 533 QTVPASLEGAPFSPA--QAGLTTKKDPTVLPLVQAAPKNSPSFQS--TSSSPEIPLSPEA 588 Query: 933 QSPQSSFPQPAAV-YAIHHQQLPHGFTNMAHVTQAHVQTGITAAPP 977 + S +P + P G + A V + G +A P Sbjct: 589 TLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGP 634 Score = 39.7 bits (91), Expect = 0.015 Identities = 35/122 (28%), Positives = 48/122 (39%), Gaps = 9/122 (7%) Query: 4 PQPLQQPSQPQQPPPTQQA--VARRPPGGTSPPNGGLPGPLATSAAPPGP-----PAAAS 56 P P P+ P PP+ + P G +PP P P + AA P P P AA+ Sbjct: 980 PSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAAT 1039 Query: 57 PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPG--AAAIGSARGQSTGKGPPQSPVF 114 P + A + L +GA A P P+ P A A + KG P +P Sbjct: 1040 PPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP 1099 Query: 115 EG 116 +G Sbjct: 1100 KG 1101 Score = 39.7 bits (91), Expect = 0.015 Identities = 39/124 (31%), Positives = 46/124 (37%), Gaps = 22/124 (17%) Query: 4 PQPLQQPSQPQQPPPTQQAVARRPPGG--TSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61 P P P+ P PP+ P GG T PP G P AT +P G A SP P Sbjct: 1143 PPPKGAPTTPAATPPS-------PKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAP 1195 Query: 62 VAAAGS------GLR----RGAEGILAPQPPPPQQHQERP---GAAAIGSARGQSTGKGP 108 A + GL +GA A PP P+ P GA +A S GP Sbjct: 1196 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGP 1255 Query: 109 PQSP 112 P Sbjct: 1256 ATPP 1259 Score = 39.7 bits (91), Expect = 0.015 Identities = 31/112 (27%), Positives = 39/112 (34%), Gaps = 6/112 (5%) Query: 3 KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPV 62 K P P + PP + + GT PP G P T +P G P P P Sbjct: 1298 KGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTL--PATTPS 1355 Query: 63 AAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQS--TGKGPPQSP 112 + G EG P P H+ P RG + + KG P SP Sbjct: 1356 SKGGPTTPSSKEGPTPPAATP--SHKGGPAMTPPSPKRGPAIPSPKGDPTSP 1405 Score = 38.5 bits (88), Expect = 0.034 Identities = 35/116 (30%), Positives = 44/116 (37%), Gaps = 14/116 (12%) Query: 4 PQPLQQPSQPQQPPPTQQAVARRPP--GGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61 P P P P PP+ + PP G + P P P A PP A +P P Sbjct: 1097 PSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1156 Query: 62 VAAAGSGLR----RGAEGILAPQPPPPQQHQERPGAAAIGSARG-QSTGKGPPQSP 112 + G GL +GA A PP P+ G A S +G +T P SP Sbjct: 1157 PSPKG-GLATPPPKGAPTTPAATPPSPK------GGLATPSPKGAPTTPAATPPSP 1205 Score = 38.5 bits (88), Expect = 0.034 Identities = 34/113 (30%), Positives = 47/113 (41%), Gaps = 11/113 (9%) Query: 4 PQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGP-LATSAAPPGPPAAASPCLGPV 62 P P P+ P PP+ + G +PP+ G P P + T +P G PA + P P Sbjct: 1258 PPPKGAPTPPAATPPSLKG------GLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPT 1311 Query: 63 -AAAGSGLRRGAEGILAPQ--PPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112 AA +G+ G P+ P PP P A S+ KG P +P Sbjct: 1312 PPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSS-KGGPTTP 1363 Score = 36.6 bits (83), Expect = 0.13 Identities = 35/119 (29%), Positives = 42/119 (35%), Gaps = 19/119 (15%) Query: 4 PQPLQQPSQPQQPPPTQQA--VARRPPGGTSPPNGGLPGPLATSAAP-----PGPPAAA- 55 P P P+ P PP+ + P +PP P P A P P PPAA Sbjct: 934 PSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATP 993 Query: 56 -SPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQST-GKGPPQSP 112 SP GP + G AP PP + AA +G ST P SP Sbjct: 994 PSPKGGPATPSPKG---------APTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSP 1043 Score = 36.6 bits (83), Expect = 0.13 Identities = 34/119 (28%), Positives = 41/119 (34%), Gaps = 19/119 (15%) Query: 4 PQPLQQPSQPQQPPPTQQ---AVARRPPGGTSPPNGGLPGPLATSAAP-----PGPPAAA 55 P P + P PP+ + A P G + P LP P A P P PPAA Sbjct: 1027 PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAAT 1086 Query: 56 --SPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112 SP GP + G AP PP + G A +T P SP Sbjct: 1087 PPSPKGGPATPSPKG---------APMPPAATPPSPKGGLATPPHKGAPTTPAATPPSP 1136 Score = 36.6 bits (83), Expect = 0.13 Identities = 33/121 (27%), Positives = 43/121 (35%), Gaps = 9/121 (7%) Query: 4 PQPLQQPSQPQQPPPTQQA--VARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61 P P P+ P PP+ + P G + P P P A PP A P P Sbjct: 1212 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP 1271 Query: 62 VAAAGSGL----RRGAEGILAPQPPPPQ--QHQERPGAAAIGSARGQSTGKGPPQSPVFE 115 + G GL +GA PP P+ P A A + KG P +P + Sbjct: 1272 PSLKG-GLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPK 1330 Query: 116 G 116 G Sbjct: 1331 G 1331 Score = 36.2 bits (82), Expect = 0.17 Identities = 27/105 (25%), Positives = 36/105 (34%), Gaps = 9/105 (8%) Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAA 65 P P PPP A PP T P G P AT+ + G P S GP A Sbjct: 1317 PPSPKGSPGTPPPKG---APTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPA 1373 Query: 66 GSGLRRGAEGILAPQP------PPPQQHQERPGAAAIGSARGQST 104 + +G + P P P P+ P + + +T Sbjct: 1374 ATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPAT 1418 Score = 35.0 bits (79), Expect = 0.38 Identities = 37/125 (29%), Positives = 45/125 (36%), Gaps = 24/125 (19%) Query: 4 PQPLQQP------SQPQQ----PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAP----- 48 P P Q P S P++ P P + P G +PP P P A P Sbjct: 903 PAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWA 962 Query: 49 PGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKG- 107 P PPAA P P + +GA A PP P+ G A S +G T Sbjct: 963 PTPPAATPP--SPKGGPATPSPKGAPTPPAATPPSPK------GGPATPSPKGAPTPPAV 1014 Query: 108 PPQSP 112 P SP Sbjct: 1015 TPPSP 1019 Score = 35.0 bits (79), Expect = 0.38 Identities = 34/120 (28%), Positives = 43/120 (35%), Gaps = 18/120 (15%) Query: 10 PSQPQQPPPTQQA--VARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGS 67 P+ P PP+ + P G PP P P A PP A +P P + G Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG- 1138 Query: 68 GLR----RGAEGILAPQP---------PPPQQHQERPGAAAIGSARGQST--GKGPPQSP 112 GL +GA A P PPP+ P A G +T KG P +P Sbjct: 1139 GLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1198 Score = 35.0 bits (79), Expect = 0.38 Identities = 28/121 (23%), Positives = 43/121 (35%), Gaps = 7/121 (5%) Query: 4 PQPLQQPSQPQQPPPTQQAVARRP---PGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 P P P+ P P + + P G +P G L P T + PA ++P G Sbjct: 1396 PSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGG 1455 Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120 P + +G + A PP P++ A S + P +P V + Sbjct: 1456 PATPSS----KGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPS 1511 Query: 121 S 121 S Sbjct: 1512 S 1512 Score = 34.7 bits (78), Expect = 0.50 Identities = 32/127 (25%), Positives = 41/127 (32%), Gaps = 20/127 (15%) Query: 4 PQPLQQPSQPQQPPPTQQA--VARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61 P P P+ P PP+ + P G + P P P A P A +P P Sbjct: 1189 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1248 Query: 62 VAAAGSGLRRGAEGILAPQPP-------------PPQQHQERPGAAAIGSARG---QSTG 105 + G +G AP PP PP + P S +G S Sbjct: 1249 PSPKGGPATPPPKG--APTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPP 1306 Query: 106 KGPPQSP 112 KG P P Sbjct: 1307 KGAPTPP 1313 Score = 33.9 bits (76), Expect = 0.85 Identities = 61/258 (23%), Positives = 96/258 (37%), Gaps = 39/258 (15%) Query: 796 PGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQAL-Y 854 PG+ P Q + P ++ ++S A + P P P PQ Sbjct: 2 PGEATETVPATE---QELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPL 58 Query: 855 ATVHQSYPHHA------TQLHAHQPQPAT---TPTGSQPQSQHAAPSPVQHQAGQAPHLG 905 + +Q+ P + T L PQ ++ P G+ P++ P+ + A L Sbjct: 59 SAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAA-LA 117 Query: 906 SGQPQQNLYHPGALTGTPPSLPP------GPSAQSPQSSFP-----QPAAVYAIHHQQLP 954 P + P L GTP S P P + S+FP P +V + Sbjct: 118 LASP---MIAP-TLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSV- 172 Query: 955 HGFTNMAHVTQAHVQTGITAAPP---PHP-GAPHPPQVMLLHPPQSHGGPPQGAVPQSGV 1010 T A + + +T + P P+P G P PP ++ P H P ++ QSGV Sbjct: 173 --ITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVP--YHCVTPMASI-QSGV 227 Query: 1011 PALSASTPSPYPYIGHPQ 1028 +L +TP+ I PQ Sbjct: 228 ASLPQTTPTTTLAIASPQ 245 Score = 32.0 bits (71), Expect = 3.2 Identities = 25/98 (25%), Positives = 34/98 (34%), Gaps = 6/98 (6%) Query: 16 PPPTQQAVARRPP-GGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAE 74 PP + A PP G +PP P P + PP A P + P + G+ Sbjct: 1294 PPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATT 1353 Query: 75 GILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112 P P + AA S +G GP +P Sbjct: 1354 PSSKGGPTTPSSKEGPTPPAATPSHKG-----GPAMTP 1386 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 97.4 bits (241), Expect = 6e-20 Identities = 192/781 (24%), Positives = 271/781 (34%), Gaps = 133/781 (17%) Query: 357 REGP-RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRP 415 R GP R S + RP S R P N+SPGP S G G +R P Q+ Sbjct: 76 RAGPTRSAGTSSRNPASRPPASGRGERAPP-AKNTSPGPVSSP-GRASGTTRPGPLGQKG 133 Query: 416 LR---------GAKT-------LSSPSNRP-SGETSVPPPPAVGRMYPPRSPKSAAPAPI 458 LR G T LS+ + R SG T P PA+ R + P P Sbjct: 134 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 193 Query: 459 SASCPEPPI-GSAVPTSSASIPVTSSVS-------DPGVGSISPASPKISLAPTDVKELS 510 ++ P PP G SSAS T+ S G G PAS +S + T + + Sbjct: 194 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253 Query: 511 TKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQF-----------------K 553 P P+ A + P + Q+ RK A K Sbjct: 254 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTK 313 Query: 554 LQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLA 613 +P P+N+ P P + P L T P+ P S S+ P Sbjct: 314 ARPVPPPDNAATPLPATLPPSPP---------LATPLPLAPPSPSAPPSLQTLPSPPATP 364 Query: 614 PSGGTEGPEQPPPPCPSQTGS-PPVGLIKGEDKDE-----GPVAEQVKKSTLNPNAKEFN 667 PS PP P + PP+ + P+A ++T + + Sbjct: 365 PSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQ 424 Query: 668 PTKPLLSVN--KSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQA 725 T L+++ ++ ++ TSP + P P L A S SP Q + PAV Sbjct: 425 ATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPL-----QTSLSPAVSP 479 Query: 726 PQ----MYPYPVSNSVPGQQGKYRGAKGSLPPQRSD--------QHQPAS--APPMMQAA 771 ++P +S+ + + +PP + Q PAS PP+ Sbjct: 480 LSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLP 539 Query: 772 AAAGPPLVAA-----TPYSSYIPYN---PQQFPGQPAMMQPMAHYPSQ----PVFAPMLQ 819 + A PPL A TP+ P P Q P P + P PS P AP Sbjct: 540 SLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSP-LTTPPPETPSSIATPPPQAPPAL 598 Query: 820 SNPRMLTSGSHPQAIVSSSTPQYP------------SAEQPTPQALYATVHQSYPHHATQ 867 ++P + S P + +++ PQ P S P + AT P+ A Sbjct: 599 ASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPN-ALA 657 Query: 868 LHAHQP--QPATTPTGSQPQSQHAAP--SPVQHQAGQAPHLGSGQPQQNLYHPGALTGTP 923 +H Q P +P P S A+P SP QAP + P Q + +P Sbjct: 658 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ-------VPPSP 710 Query: 924 PSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPH--PG 981 P+ PP + +P P P A + P M+ +A PPP P Sbjct: 711 PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSP----------SATPPPRVPPL 760 Query: 982 APHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGG 1041 PP + PP S P P PAL+ TP P + P PGQAP P Sbjct: 761 LAAPPLQVPPSPPASLPMSPLAKPPPQAPPALA--TP-PLQALPSPPASFPGQAPFSPSA 817 Query: 1042 A 1042 + Sbjct: 818 S 818 Score = 86.7 bits (213), Expect = 1e-16 Identities = 167/715 (23%), Positives = 229/715 (32%), Gaps = 89/715 (12%) Query: 334 GSGRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPG 393 G G + P+ S PL R GP S+RG PR P H P Sbjct: 231 GGGLQRPASRSLSSSATPLSSPARSGP-------SARG--------TPRAPAHPSQPKPK 275 Query: 394 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYP---PRSP 450 R P R + L++PS + VPPP P P SP Sbjct: 276 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSP 335 Query: 451 KSAAPAPISASCPE-PPIGSAVPTSSASIPVTS--SVSDPGVGSISPASPKISLAPTDVK 507 A P P++ P PP +P+ A+ P + S++ P + A P + P Sbjct: 336 PLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPM----QAPPSLQTIPPIQV 391 Query: 508 ELSTKEPGRTLEPQELARIAGKVP---GLQNEQKRFQLEELRKFGAQFKLQPSSSPENSL 564 S P P LA + + G Q + Q L S P ++ Sbjct: 392 PHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTP 451 Query: 565 DPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT-----ESVSDKEDKPPLAPSGGTE 619 PP + P + P SP+SS +++S P AP Sbjct: 452 PDSPPL---QAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLI 508 Query: 620 GP--EQPPPPCPSQTGSPPVGLIKGEDKDEGPVAE---QVKKSTLNPNAKEFNPTKPLLS 674 P E P +PP L ++ +A Q + L E P Sbjct: 509 MPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP 568 Query: 675 VNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVS 734 + S T+P P T S+ + P A + L SP + +P + P P P ++ Sbjct: 569 LQAPPSPLTTPPPETPSSIATPPPQAPPA-LASPP-LQGLPSPPLSPLATPPPQAPPXLA 626 Query: 735 NSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQ 794 LPP ++ PAS PP+ A + A + P++P Sbjct: 627 ----------------LPPLQAPPSPPAS-PPLSPLATPSPQAPNALAVHLLQAPFSPPP 669 Query: 795 FPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALY 854 P A P A P P P Q+ P + +S P PSA P Sbjct: 670 SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP------ 723 Query: 855 ATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLY 914 P L A Q +P S P S A P P + P L + P Q Sbjct: 724 -------PQAPPPLAAPPLQVPPSPPASPPMSPSATPPP------RVPPLLAAPPLQVPP 770 Query: 915 HPGA------LTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHV 968 P A L PP PP A P + P P A + P M+ + Sbjct: 771 SPPASLPMSPLAKPPPQAPPA-LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 829 Query: 969 QTGITAAPPPHPGAPHPPQVMLLHPPQSHGGP-PQGAVPQSGVPALSASTPSPYP 1022 Q A P P PP L P+ P P +V SG A P P P Sbjct: 830 QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV--SGPRLTLALAPGPPP 882 Score = 78.6 bits (192), Expect = 3e-14 Identities = 165/706 (23%), Positives = 243/706 (34%), Gaps = 93/706 (13%) Query: 357 REGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPL 416 R+ + G + PGL L PR P SP P P ++P A R L Sbjct: 5 RDKAKAGAAARTPAARAPGL--LTPRPP-----GSPRP----------PPPVTPAALRVL 47 Query: 417 RGAKTLSSP--SNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTS 474 A + + R G P + R P RS +++ P S P G P + Sbjct: 48 GAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRP-PASGRGERAPPA 106 Query: 475 SASIPVTSSVSDPG-------VGSISPASPKISLAPTDVKELSTKEPGRTLEPQELAR-I 526 + P VS PG G + +IS T + +T+ P R+ R Sbjct: 107 KNTSP--GPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDT 164 Query: 527 AGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGL 586 +G PG + R G + L P S P PP E P+ Sbjct: 165 SGPTPGTPSPA---MARRSRAAGTEVGLP---RPAPSARPRPPT---EGPRKSVSSASEH 215 Query: 587 LTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGP-EQPPPPCPSQTGSPPVGLIKGEDK 645 T+EP SP + + S +P + P P PS G+P + K Sbjct: 216 STTEP--SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK 273 Query: 646 DEGPVAEQVKKSTLNPNAKEFNPTK-PLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSG 704 +G + ++ + P K+ P PL S +T +P+ R P + Sbjct: 274 PKG--LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATL 331 Query: 705 LYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASA 764 SP + +P P+ P + P + P Q PP + P A Sbjct: 332 PPSPPLATPLPLAPPSPSAP-PSLQTLPSPPATPPSQA---------PPSMTTP--PMQA 379 Query: 765 PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRM 824 PP +Q PP+ P+S P Q P P + + S + +P LQ+ Sbjct: 380 PPSLQTI----PPI--QVPHSLTSP--SLQAPPSPLALSSLQATTS--LGSPTLQATHSF 429 Query: 825 LTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQP 884 LT S Q S ++P P++ P L A + L A P + P Sbjct: 430 LTM-SPRQTQASLTSPSRPASTPPDSPPLQAPL---------SLPASPPLQTSLSPAVSP 479 Query: 885 QSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAA 944 S P+Q + A H P +L P T + SL P PS Q+P +S P Sbjct: 480 LSSPLTIHPLQALSSLASHSPQA-PLSSLIMPPLETQS--SLAP-PSLQTPPASLTTPP- 534 Query: 945 VYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHP--------PQVMLLHPPQS 996 + + P T A +T H++T AP P P P P + PPQ+ Sbjct: 535 LENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQA 594 Query: 997 H---GGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFP 1039 PP +P + L+ P P + P + P P P Sbjct: 595 PPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASP 640 Score = 47.0 bits (110), Expect = 1e-04 Identities = 60/246 (24%), Positives = 86/246 (34%), Gaps = 20/246 (8%) Query: 392 PGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPP-PPAVGRMYPPRSP 450 P P +A +SP A P + +L++P VPP PPA M P +P Sbjct: 669 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP------LQVPPSPPASPPMSPSATP 722 Query: 451 KSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELS 510 AP P++A PP+ P+ AS P++ S + P A+P + + P+ L Sbjct: 723 PPQAPPPLAA----PPL-QVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLP 777 Query: 511 TKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPR 570 + A + L + F + A + P ++P P Sbjct: 778 MSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 837 Query: 571 ILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPS 630 L + P P P SVS LAP GP PP PS Sbjct: 838 PLLQVPPSPPASPT---LQAPRRPPTPGPDTSVSGPRLTLALAP-----GPPPPPSRSPS 889 Query: 631 QTGSPP 636 T S P Sbjct: 890 STLSGP 895 Score = 46.2 bits (108), Expect = 2e-04 Identities = 43/134 (32%), Positives = 51/134 (38%), Gaps = 30/134 (22%) Query: 4 PQPLQQPSQP--QQPPPTQQAVA----RRPPGGTSPPNGGLP----GPLATS-------- 45 P PLQ P P PP T ++A + PP SPP GLP PLAT Sbjct: 566 PCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXL 625 Query: 46 -----AAPPGPPAAASPCLGPVAAAGSGLRRG-----AEGILAPQPPPPQQHQERPGAAA 95 APP PP ASP L P+A + +P P PP Q P A+ Sbjct: 626 ALPPLQAPPSPP--ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 683 Query: 96 IGSARGQSTGKGPP 109 S + PP Sbjct: 684 PVSPSATPPSQAPP 697 Score = 37.7 bits (86), Expect = 0.059 Identities = 33/123 (26%), Positives = 43/123 (34%), Gaps = 18/123 (14%) Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTS------------PPNGGLPGPLATSAAPPGPPA 53 PLQ P P PP P + PP+ + P + A+PP P+ Sbjct: 629 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 688 Query: 54 AASPCLGPVAAAGSGLR----RGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109 A P P + A L+ A ++P PP Q P AA S PP Sbjct: 689 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP--QAPPPLAAPPLQVPPSPPASPP 746 Query: 110 QSP 112 SP Sbjct: 747 MSP 749 Score = 37.0 bits (84), Expect = 0.10 Identities = 39/122 (31%), Positives = 48/122 (39%), Gaps = 30/122 (24%) Query: 13 PQQPP--PTQQAVARRPPGGTSPPNGGLPGP---LATSAAPPGPP--AAASPCLGPVAAA 65 P PP PT QA RRPP T P+ + GP LA + PP PP + +S GP A Sbjct: 843 PPSPPASPTLQA-PRRPP--TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 899 Query: 66 GS-----------GLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVF 114 S G G EG A PPP A + + + +GP F Sbjct: 900 HSSSATSTPEELRGYDSGPEGGAAASPPPD---------AELAACHPAAWSRGPAPPLAF 950 Query: 115 EG 116 G Sbjct: 951 RG 952 Score = 36.2 bits (82), Expect = 0.17 Identities = 34/112 (30%), Positives = 43/112 (38%), Gaps = 6/112 (5%) Query: 3 KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAP-PGPPAAASPCLGP 61 KP+ LQ PQ PP + A P +SP P P T A P P P AA+P P Sbjct: 273 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPL--ATPSPSGTKARPVPPPDNAATPL--P 328 Query: 62 VAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP-QSP 112 S + P P P Q P A ++ + PP Q+P Sbjct: 329 ATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAP 380 Score = 33.5 bits (75), Expect = 1.1 Identities = 32/113 (28%), Positives = 39/113 (34%), Gaps = 24/113 (21%) Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLP--GPLATSAAPPGPPAAASPCL 59 L PLQ P P PP + PP PP P P + A+PP P+A P Sbjct: 699 LAAPPLQVPPSPPASPPMSPSAT--PPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPR 756 Query: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112 P A L+ + P PP S K PPQ+P Sbjct: 757 VPPLLAAPPLQ------VPPSPP--------------ASLPMSPLAKPPPQAP 789 Score = 32.3 bits (72), Expect = 2.5 Identities = 38/130 (29%), Positives = 48/130 (36%), Gaps = 22/130 (16%) Query: 2 LKPQPLQQPSQPQQPPPTQQAVA---RRPPGGTSPPNGGLPGPLATS-----AAPP--GP 51 L PLQ P P PP + R PP +PP P P A+ A PP P Sbjct: 730 LAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAP 789 Query: 52 PAAASPCL-----GPVAAAGSG-LRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTG 105 PA A+P L P + G A ++P PP P A + +A Sbjct: 790 PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP------PQAPPVLAAPLLQVP 843 Query: 106 KGPPQSPVFE 115 PP SP + Sbjct: 844 PSPPASPTLQ 853 Score = 31.6 bits (70), Expect = 4.2 Identities = 29/91 (31%), Positives = 34/91 (37%), Gaps = 13/91 (14%) Query: 16 PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEG 75 PPP + A P + P PLA AP G P P GP +A G EG Sbjct: 926 PPPDAELAACHPAAWSRGP----APPLAFRGAP-GAPLPWPPATGPGSADGLCTIYETEG 980 Query: 76 ILAPQPPPPQQHQERPGAAAIGSARGQSTGK 106 P+ PGA G + G S GK Sbjct: 981 --------PESATPAPGALDPGPSPGTSGGK 1003 Score = 30.4 bits (67), Expect = 9.4 Identities = 20/73 (27%), Positives = 29/73 (39%), Gaps = 2/73 (2%) Query: 11 SQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLR 70 S P + P+ + R P + P GL PP AA P LGP++++ Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA--PALGPLSSSPLATP 307 Query: 71 RGAEGILAPQPPP 83 + P PPP Sbjct: 308 SPSGTKARPVPPP 320 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 97.1 bits (240), Expect = 8e-20 Identities = 172/717 (23%), Positives = 246/717 (34%), Gaps = 117/717 (16%) Query: 381 PRGPH--HLDNSSPGP-GSEARGINGGPSRMSPKAQRPLRGAKTL-----SSPSNRPSGE 432 P+G H + PGP EA+ + ++ P+ + PL L SP + P E Sbjct: 396 PKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEE 455 Query: 433 TSVPPPPAVGRMYPPRSPKSAAPAP----ISASCPEPPIGSAVPTSSASIPVTSSVSDPG 488 + PPP R+ PP A+P P +S E P+ S S P SS P Sbjct: 456 SPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSP- 514 Query: 489 VGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKF 548 SP SP P+ E P E L+ P + EEL Sbjct: 515 -LEESPLSPPEESPPSPALETPLSPPP---EASPLS------PPFEESPLSPPPEELPTS 564 Query: 549 GAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGL--------LTSEPMGSPVSSKT 600 + S PE S PP +E P E L L+ P SP+S Sbjct: 565 PPPEASRLSPPPEESPMSPPP---EESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPP 621 Query: 601 ES--VSDKEDKPPLAPSGGTEGPEQPPP--------PCPSQTGSPPVGLIKGEDKDEGPV 650 E+ +S + P++P E P PPP P S+ PP +E P Sbjct: 622 EASRLSPPPEDSPMSPP-PEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPT 680 Query: 651 AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGL-YSPQ 709 + + S L+P E +PT P +P SP P S S+P+ + L PQ Sbjct: 681 SPPPEASRLSP-PPEDSPTSP-----PPEDSPASPPPE-DSLMSLPLEESPLLPLPEEPQ 733 Query: 710 YISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQH-QPASAPPMM 768 H+ P + P + P P + L PQ + H P P + Sbjct: 734 LCPRSEGPHLSPRPEEPHLSPRP--------------EEPHLSPQAEEPHLSPQPEEPCL 779 Query: 769 QAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQP-MAHYPSQPVFAPMLQS------- 820 A P ++ ++ P++ P +P ++ P +P +P + Sbjct: 780 --CAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQS 837 Query: 821 -----NPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQP 875 +PR S P+ P P E+P + + P L +P Sbjct: 838 EEPCLSPRPEESHLSPEL---EKPPLSPRPEKPPEEPGQCPAPEELP-----LFPPPGEP 889 Query: 876 ATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQP--QQNLYHPGALTGTPPSLPP----- 928 + +P +P P+ + P SG+P L P L PP L P Sbjct: 890 SLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPL---PPPLSPIITAA 946 Query: 929 GPSAQSPQSSFPQPAAVYAIHHQQLPHGF----TNMAHVTQAHVQTGITAAP---PPHPG 981 P A SP P + P T ++ +A+ P PP PG Sbjct: 947 APPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPG 1006 Query: 982 APHPPQVMLLH---PPQ-----SHGGPPQGAVP-QSGVPALSASTPSPYPYIGHPQG 1029 +P P +L PPQ H PQ + P Q PAL S PSP IG G Sbjct: 1007 SPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVG 1063 Score = 55.1 bits (131), Expect = 4e-07 Identities = 141/594 (23%), Positives = 202/594 (34%), Gaps = 98/594 (16%) Query: 422 LSSPSNRPSGETSVPPPP-AVGRMYPPRSP-----KSAAPAPISASCP---EPPIGSAVP 472 ++ ++RP+ +PP P A+G P +P PA +S S +PP GS Sbjct: 2093 IARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPG 2152 Query: 473 TSSAS---------IPVTSSVSDP-GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQE 522 S +P DP G+ P P+ AP + G +P Sbjct: 2153 PDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPT-GAPAQPPM 2211 Query: 523 LARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRI----LKEEPK- 577 L A PG Q E S+P+ L P P + + E P Sbjct: 2212 LG--ASSRPGAG------QPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGV 2263 Query: 578 GKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPV 637 G K + LL+ P G S K V KE+ +PS G PP SP Sbjct: 2264 GGGKASEPLLSPPPFGE--SRKALEVK-KEELGASSPSYG--------PPNLGFVDSPSS 2312 Query: 638 GLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPV 697 G G + + P V K+ L P A + P P L + P P P PS P Sbjct: 2313 GTHLGGLELKTP---DVFKAPLTPRASQVEPQSPGLGLR-----PQEPPPAQALAPSPP- 2363 Query: 698 LTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQ---GKYRGAKGSLPPQ 754 ++ P SY P PQ P ++P + + S P Sbjct: 2364 ---SHPDIFRPG--SYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPAS-PQS 2417 Query: 755 RSDQHQPASAPPMMQAAAAAGPPLVAATP-YSSYIPYNPQQFPGQPAMMQPMA--HYPSQ 811 +S P + P+ A P TP + S PY+ P +P P A H P + Sbjct: 2418 QSSSQSPLTPRPLSAEAFCPSP----VTPRFQSPDPYSRP--PSRPQSRDPFAPLHKPPR 2471 Query: 812 PVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAE--------QPTPQALYATVHQSYPH 863 P P + L S ++ P P+ E QP P + + ++ Sbjct: 2472 PQ-PPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQP-PNFVRSPGTGAFVG 2529 Query: 864 HATQLHAHQPQPATTPTGSQPQSQHAAPSP--VQHQAGQAPHLGSGQPQQNLYHPGALTG 921 + + PQ P+ P Q P P + G P LG +PQ Y Sbjct: 2530 TPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLG--KPQSTNYTVATGNF 2587 Query: 922 TPPSLPPGPSAQS-----------PQSSFPQPAAVYAIHHQQLPHGFTNMAHVT 964 P P GPS+ S P S P PA ++ + L HG + + +T Sbjct: 2588 HPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPY--LSHGASQRSGIT 2639 Score = 53.9 bits (128), Expect = 8e-07 Identities = 162/801 (20%), Positives = 262/801 (32%), Gaps = 142/801 (17%) Query: 308 QYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIP-----LPQRVREGPRG 362 +YR + + + ++++HSAV + L G+ +P PQ G G Sbjct: 3594 EYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAG 3653 Query: 363 GVRCSSSRGGRPGLSSLP-----------------------PRG---PHHLDNSSPGPGS 396 G+R + PG P P G P +L S GP S Sbjct: 3654 GLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDS 3713 Query: 397 ---EARGINGGPSRMS-----------PKAQRPLRGAKTLSSPSNR-PSGETSVPPPPAV 441 + R + RM + Q+ L G + + P +T+ P Sbjct: 3714 RLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKP 3773 Query: 442 GRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISL 501 + PP S + +S P+ P G P A + G++ P P + Sbjct: 3774 QGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVL------QQQHPGALGPQGPHRQV 3827 Query: 502 APTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPS---- 557 T + LS+ + L Q + ++ Q +Q++ Q ++ LQ S Sbjct: 3828 LMTQSRVLSSPQ----LAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSH 3883 Query: 558 -SSPENSLDPFPP-RILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPS 615 P+ S P + L+++ + ++++ + + + + + ++ + L Sbjct: 3884 SGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQ 3943 Query: 616 GGTE----------GPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKE 665 + +Q Q +GL+ P +Q ++ L P Sbjct: 3944 QQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGM-- 4001 Query: 666 FNPTKPLL--------------------SVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGL 705 P KPL +V+ + S+ + GP TH + + T +S Sbjct: 4002 --PAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMA 4059 Query: 706 YSPQYISYIPQIHMGPAVQAPQMYPYPVSNSV--------PGQQGK-----YRGAKGSLP 752 P + P + + Q P P +S+ PGQQ + + GS Sbjct: 4060 TEPGEVK--PSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHG 4117 Query: 753 PQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHY--PS 810 S AS+ P + A P V+ + N P QP + +PM + P Sbjct: 4118 QLGSGSSSEASSVPHLLAQ-----PSVSLGDQPGSMTQNLLG-PQQPMLERPMQNNTGPQ 4171 Query: 811 QPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHA 870 P P+LQS + G P + Q A+ P + L Q Q Sbjct: 4172 PPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQL 4231 Query: 871 HQPQPAT-TPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPG 929 Q Q TP +P +Q SP+Q G P LG PG TG L G Sbjct: 4232 QQSQAVRQTPPYQEPGTQ---TSPLQGLLGCQPQLGG--------FPGPQTGPLQELGAG 4280 Query: 930 PSAQSPQ---------SSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAA-PPPH 979 P Q P S+ P V+ P + + Q A PP H Sbjct: 4281 PRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTH 4340 Query: 980 PGAPHPPQVMLLHPPQSHGGP 1000 PG P PQ L PP P Sbjct: 4341 PGTP-KPQGPTLEPPPGRVSP 4360 Score = 53.1 bits (126), Expect = 1e-06 Identities = 112/505 (22%), Positives = 157/505 (31%), Gaps = 108/505 (21%) Query: 341 SLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPH--------------- 385 SL E +PLP+ + PR S R P LS P PH Sbjct: 717 SLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEE-PHLSPQAEEPHLSPQPE 775 Query: 386 -----------HLDNSSPGP--GSEARGINGGPS----RMSPKAQRPLRGAKTLSSPSNR 428 HL + GP + ++ P +SP + P + S + Sbjct: 776 EPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSP 835 Query: 429 PSGETSVPPPPAVGRM-----YPPRSPKSAAPAPISASCPEPPIGSAVP----TSSASIP 479 S E + P P + PP SP+ P CP P P S + + Sbjct: 836 QSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLL 895 Query: 480 VTSSVSDPGVGSISPASPKISLAPTDVKELSTK-EPGRTLEPQELARIAGKVPGLQNEQK 538 ++S+PG +SP ++ L+P+ LS + P L P I P Sbjct: 896 GEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPP------ 949 Query: 539 RFQLEELRKFGAQFKLQPSSSPENSL--------------------DPFPPRILKEEPKG 578 L L + F + S PE+ L +P PP IL P Sbjct: 950 --ALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGS 1007 Query: 579 KEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSP--P 636 +L EP+ S + ++ PP S PP P SP P Sbjct: 1008 PVGPASPIL-MEPLPPQCSPLLQHSLVPQNSPPSQCS---------PPALPLSVPSPLSP 1057 Query: 637 VGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNP--TKPLLSVNKSTSTPT-SPGPRTHSTP 693 +G + G DE + E + P P T PL S S P SP P Sbjct: 1058 IGKVVGV-SDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFS 1116 Query: 694 SIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQ-QGKYRGAKGSLP 752 + TA G + AP P P PG + +G+ L Sbjct: 1117 GLGEDTAPLDG------------------IDAPGSQPEP--GQTPGSLASELKGSPVLLD 1156 Query: 753 PQRSDQHQPASAPPMMQAAAAAGPP 777 P+ P P + A G P Sbjct: 1157 PEELAPVTPMEVYPECKQTAGQGSP 1181 Score = 45.8 bits (107), Expect = 2e-04 Identities = 162/717 (22%), Positives = 240/717 (33%), Gaps = 148/717 (20%) Query: 377 SSLPPRGPHHL---DNSSPGP---GSEARGINGGPSRMSPKAQRPLRGAKTLS-SPSNRP 429 +S P GP +L D+ S G G E + + + ++P+A + + L P P Sbjct: 2294 ASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPP 2353 Query: 430 SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGV 489 + P PP+ ++ P S P P+PP P S ++P S SDP Sbjct: 2354 PAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPP----PPESCCALPPRSLPSDPF- 2408 Query: 490 GSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFG 549 S PASP+ + S++ P L P+ L+ A + RFQ + Sbjct: 2409 -SRVPASPQ--------SQSSSQSP---LTPRPLSAEAFCPSPVT---PRFQSPDPYS-- 2451 Query: 550 AQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD---GLLTSEPMGS---PVSSKTESV 603 +P S P+ S DPF P L + P+ + EV G L +G+ P + Sbjct: 2452 -----RPPSRPQ-SRDPFAP--LHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPA 2503 Query: 604 SDKEDKPPLAP---------SGGTEGPEQP--------------PPPCPSQTGSPPVGLI 640 + K P +G G P PP P PP G+ Sbjct: 2504 GELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGI- 2562 Query: 641 KGEDKDEGPVAEQVKKSTLNPNAKEFNPT-KPLLSVNKSTST--------PTSPGPRTHS 691 GP + + + F+P+ PL + ST P S P Sbjct: 2563 -NSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAP 2621 Query: 692 TPSIPVLTAG---QSGLYSPQYISYIPQIHMG--------PAVQAPQMYPYPVS------ 734 S+P L+ G +SG+ SP P MG P Q P M + Sbjct: 2622 DGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQR 2681 Query: 735 ----------------NSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPL 778 N++ ++ A G++ P S +P+S P + + P Sbjct: 2682 QRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSS--PAFEQLSRGQTPF 2739 Query: 779 VAATPYSSYIPYNPQQFPGQ---PAMM--QPMAHYPSQPVFAPMLQSNPRMLTSGSHPQA 833 SS + P + G P P P + N R L GS QA Sbjct: 2740 AGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGS--QA 2797 Query: 834 IVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQ-SQHAAPS 892 + YP + P Q Q AT + A P+ P+ + A S Sbjct: 2798 FYQRAP--YPGS-LPLQQQQQQLWQQQQATAATSMRF--AMSARFPSTPGPELGRQALGS 2852 Query: 893 PVQHQAGQAPHLGSGQPQQNLYHPGALT--------GTPPSLPPGPSAQSPQSSFPQPAA 944 P+ + + P G G+P P G P P P PQ P+ Sbjct: 2853 PLAGISTRLP--GPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQR--PRFYP 2908 Query: 945 VYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQV-MLLHPPQSHGGP 1000 V H+ P G +A ++ PP P AP P++ LHP GP Sbjct: 2909 VSEDPHRLAPEGLRGLA----------VSGLPPQKPSAPPAPELNNSLHPTPHTKGP 2955 Score = 43.9 bits (102), Expect = 8e-04 Identities = 88/358 (24%), Positives = 135/358 (37%), Gaps = 61/358 (17%) Query: 361 RGGVRCSSSRGGRPGLSSLP---------PRGPHHLDNSSPGPGSEARGINGGPSRMSP- 410 +G + C GG PG + P P+GP L PG+ + G GP +P Sbjct: 4254 QGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAP---PGALSTGPVLGPVHPTPP 4310 Query: 411 --KAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIG 468 Q P R ++ L SPS++ E +PP P +PK P EPP G Sbjct: 4311 PSSPQEPKRPSQ-LPSPSSQLPTEAQLPPT-------HPGTPKPQGPT------LEPPPG 4356 Query: 469 SAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAG 528 P A+ + ++ G+G P P +LA T E S+ PG L ++ G Sbjct: 4357 RVSP---AAAQLADTLFSKGLG---PWDPPDNLAETQKPEQSSLVPG------HLDQVNG 4404 Query: 529 KV--PGLQNEQKRFQLEELRKFGAQ-FKLQPSSSP------ENSLDPFPPR------ILK 573 +V Q K+ EE GAQ K + + P N L PR +L+ Sbjct: 4405 QVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQ 4464 Query: 574 EEPKGKEKEVDGLLTSEPMGSPVSSKTES-VSDKEDKPPLAPSGGTEG----PEQPPPPC 628 + + K ++ SE + + ++ +S ++ E K PS + P P P Sbjct: 4465 KLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPLTPKPKR 4524 Query: 629 PSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPG 686 + V K K++G A + L T+P ++ N S P G Sbjct: 4525 VQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSG 4582 Score = 39.3 bits (90), Expect = 0.020 Identities = 33/112 (29%), Positives = 43/112 (38%), Gaps = 22/112 (19%) Query: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 +L + LQQ +Q PP Q+ PG + P GL G PGP G Sbjct: 4225 LLMQRQLQQSQAVRQTPPYQE------PGTQTSPLQGLLGCQPQLGGFPGPQT------G 4272 Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112 P+ G+G P+P P + PGA + G G PP SP Sbjct: 4273 PLQELGAG----------PRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSP 4314 Score = 38.5 bits (88), Expect = 0.034 Identities = 80/328 (24%), Positives = 110/328 (33%), Gaps = 48/328 (14%) Query: 721 PAVQAPQMY---PYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPP 777 P AP ++ P + G + GS+P S PP + A + P Sbjct: 2117 PPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDP 2176 Query: 778 LVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQA---- 833 A Y P P+ FP P P YPS P AP + P ML + S P A Sbjct: 2177 FGLAPAY----PLEPR-FPTAPPTYPP---YPS-PTGAP---AQPPMLGASSRPGAGQPG 2224 Query: 834 IVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLH-------AHQPQPATTPTGSQPQS 886 ++ P P + TP S + A A +P + P G ++ Sbjct: 2225 EFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKA 2284 Query: 887 QHAAPSPVQHQAGQ--APHLGSGQPQQNLYHPGALTGTPPS-----LPPGPSAQSPQS-- 937 + + P+LG + H G L P L P S PQS Sbjct: 2285 LEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPG 2344 Query: 938 -----SFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLH 992 P PA A P F ++ T + Q +T P P P P+ Sbjct: 2345 LGLRPQEPPPAQALAPSPPSHPDIFRPGSY-TDPYAQPPLTPRPQPPP-----PESCCAL 2398 Query: 993 PPQSHGGPPQGAVPQSGVPALSASTPSP 1020 PP+S P VP S P +S+ SP Sbjct: 2399 PPRSLPSDPFSRVPAS--PQSQSSSQSP 2424 Score = 34.3 bits (77), Expect = 0.65 Identities = 32/120 (26%), Positives = 43/120 (35%), Gaps = 10/120 (8%) Query: 2 LKPQPLQQPSQ--PQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCL 59 L+ PL P + P PPP + SPP P P + P PP ASP Sbjct: 489 LEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALET--PLSPPPEASPLS 546 Query: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS----PVFE 115 P S L E + PP + P + + +S PP++ P FE Sbjct: 547 PPFEE--SPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFE 604 Score = 33.9 bits (76), Expect = 0.85 Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 21/97 (21%) Query: 2 LKPQ-PLQQPSQPQQPPPTQQAVARRPP--GGTSPPNGGLPGPLATSAAPPG----PPAA 54 L+P+ P P+ P P PT +PP G +S P G PG T+ PPG P+ Sbjct: 2185 LEPRFPTAPPTYPPYPSPT--GAPAQPPMLGASSRPGAGQPGEFHTT--PPGTPRHQPST 2240 Query: 55 ASPCLGP----------VAAAGSGLRRGAEGILAPQP 81 P L P + G G + +E +L+P P Sbjct: 2241 PDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPP 2277 Score = 33.9 bits (76), Expect = 0.85 Identities = 85/391 (21%), Positives = 128/391 (32%), Gaps = 66/391 (16%) Query: 561 ENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEG 620 +N++DP + E +G G P+ + ++ + E KP L+ Sbjct: 4026 QNTVDP---AVSSEATEGPSTHQGG-----PLAIGTTPESMATEPGEVKPSLSGDSQLLL 4077 Query: 621 PEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQV---KKSTLNPNAKEFNPTKPLLSVNK 677 + P P PS P + G+ + + + L + + P L Sbjct: 4078 VQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQP 4137 Query: 678 STSTPTSPGPRTHST--PSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSN 735 S S PG T + P P+L PQ GP +Q+ Q P Sbjct: 4138 SVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQ------PPKPGPVLQSGQGLPGVGIM 4191 Query: 736 SVPGQ-QGKYRGAKGSLP------PQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYI 788 GQ + + +G P PQ+ Q Q +Q + A V TP Sbjct: 4192 PTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQA-----VRQTP----- 4241 Query: 789 PYNPQQFPG-QPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQ 847 P Q PG Q + +Q + Q P Q+ P Q + + PQ P Sbjct: 4242 ---PYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPL--------QELGAGPRPQGPP-RL 4289 Query: 848 PTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSG 907 P P +T P H T P ++P + SQ +PS Q P Sbjct: 4290 PAPPGALSTGPVLGPVHPTP-------PPSSPQEPKRPSQLPSPSSQLPTEAQLPPT--- 4339 Query: 908 QPQQNLYHPGALTGTPPSLPPGPSAQSPQSS 938 HPG P+L P P SP ++ Sbjct: 4340 -------HPGTPKPQGPTLEPPPGRVSPAAA 4363 Score = 33.5 bits (75), Expect = 1.1 Identities = 34/125 (27%), Positives = 50/125 (40%), Gaps = 16/125 (12%) Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61 L P+P + P +P Q P ++ PPG P L G A S PG P SP Sbjct: 860 LSPRPEKPPEEPGQCPAPEELPLFPPPG--EPSLSPLLGEPALS--EPGEP-PLSPLPEE 914 Query: 62 VAAAGSGLRRGAEGILAPQPPPPQ-----QHQERPGAAAIG------SARGQSTGKGPPQ 110 + + SG + ++ P P PP P + +G A+G S + P Sbjct: 915 LPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLA 974 Query: 111 SPVFE 115 +P+ E Sbjct: 975 APILE 979 Score = 32.7 bits (73), Expect = 1.9 Identities = 88/391 (22%), Positives = 121/391 (30%), Gaps = 83/391 (21%) Query: 740 QQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQP 799 QQ + + G + Q+ Q P +Q A GP P SS+ QQ QP Sbjct: 3740 QQQQQQHLLGQVAIQQQQQQGPG-----VQTNQALGPKPQGLMPPSSHQGLLVQQLSPQP 3794 Query: 800 AMMQPMAHYPSQPVFAPMLQSNPRML-TSGSHPQAIVSSS----TPQYPSAEQPTPQALY 854 P+Q A + Q +P L G H Q +++ S +PQ Q Sbjct: 3795 PQGPQGMLGPAQ--VAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRL 3852 Query: 855 ATVHQ----------------SYPHHATQLHAHQPQPATTPTGS--------QPQSQHAA 890 T Q S+ + H+ QP+ + P GS Q Q Q Sbjct: 3853 VTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQL 3912 Query: 891 PSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHH 950 Q Q Q L Q QQ L Q Q Q + Sbjct: 3913 QQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQ--QQQQQLQQQQQQQQQQFQQQQ 3970 Query: 951 QQLPHGFTNMAHV---------TQAHVQTGITAAPPPH---PGAPHPPQVM--------- 989 QQ G N + Q + G+ A P H PGA P ++ Sbjct: 3971 QQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVD 4030 Query: 990 ------LLHPPQSHGGPPQ--GAVPQSGV-------PALSAST------PSPYPYIGHPQ 1028 P +H G P G P+S P+LS + P P P Q Sbjct: 4031 PAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQ 4090 Query: 1029 GEQPGQAPGFPGGADDRIREFSLAGGIWHGR 1059 + P + PG ++ AGG HG+ Sbjct: 4091 LQPPLR---LPGQQQQQVSLLHTAGGGSHGQ 4118 Score = 32.0 bits (71), Expect = 3.2 Identities = 38/130 (29%), Positives = 46/130 (35%), Gaps = 28/130 (21%) Query: 1 MLKPQPLQQPSQPQQPPP-------TQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPA 53 +++PQP QPS Q PP QQ GG S G G ++S A P Sbjct: 4077 LVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGS---HGQLGSGSSSEASSVPHL 4133 Query: 54 AASPCLGPVAAAGS-----------GLRRGAEGILAPQPPPP----QQHQERPGAA---A 95 A P + GS L R + PQPP P Q Q PG Sbjct: 4134 LAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPT 4193 Query: 96 IGSARGQSTG 105 +G R Q G Sbjct: 4194 VGQLRAQLQG 4203 Score = 31.6 bits (70), Expect = 4.2 Identities = 22/74 (29%), Positives = 27/74 (36%), Gaps = 1/74 (1%) Query: 16 PPPTQQAVARRPPGGTSPPNGGLPG-PLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAE 74 PP V + P G +P P P A PP P +P P+ A S G Sbjct: 2164 PPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQP 2223 Query: 75 GILAPQPPPPQQHQ 88 G PP +HQ Sbjct: 2224 GEFHTTPPGTPRHQ 2237 Score = 31.2 bits (69), Expect = 5.5 Identities = 34/124 (27%), Positives = 44/124 (35%), Gaps = 23/124 (18%) Query: 3 KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPV 62 K Q QQ Q QQ Q A+ ++ G PG A P P P Sbjct: 3733 KLQQQQQQQQQQQHLLGQVAIQQQQQQG--------PGVQTNQALGPKPQGLMPPS---- 3780 Query: 63 AAAGSGLRRGAEGILAPQ--PPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120 +G+L Q P PPQ Q G A + + Q G PQ P + + Sbjct: 3781 ---------SHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQ 3831 Query: 121 SRML 124 SR+L Sbjct: 3832 SRVL 3835 Score = 31.2 bits (69), Expect = 5.5 Identities = 31/112 (27%), Positives = 42/112 (37%), Gaps = 22/112 (19%) Query: 834 IVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSP 893 I+S + P+ E PT SY ++ + L Q A P P APSP Sbjct: 4875 ILSLLKQESPAPEPPT--------QHSYTYNVSNLDVRQLS-APPPEEPSPPPSPLAPSP 4925 Query: 894 VQHQAGQAPHLGSGQPQQNLYH-PGALTGTPPSLPPGPSAQSPQSSFPQPAA 944 + P + L P PP P P A SP+S+ P+P A Sbjct: 4926 ------------ASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRA 4965 Score = 30.4 bits (67), Expect = 9.4 Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 11/93 (11%) Query: 5 QPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAA 64 +PL++ P PPP + ++ PP +SP + PL+ P PA +P L P Sbjct: 487 RPLEE--SPLSPPPEESPLS--PPPESSPFSPLEESPLSPPEESPPSPALETP-LSPPPE 541 Query: 65 AGSGLRRGAEGILAPQP------PPPQQHQERP 91 A E L+P P PPP+ + P Sbjct: 542 ASPLSPPFEESPLSPPPEELPTSPPPEASRLSP 574 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 92.8 bits (229), Expect = 2e-18 Identities = 171/722 (23%), Positives = 246/722 (34%), Gaps = 117/722 (16%) Query: 357 REGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGING-GPSRMSPKAQRP 415 R+ + G + PGL L PR P P + R + G P A+R Sbjct: 5 RDKAKAGAAARTPAARAPGL--LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERA 62 Query: 416 LRGAKTLSSPSNRP-SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTS 474 G + P + P +G T PPA GR K+ +P P+S+ P G+ P Sbjct: 63 -GGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSS--PGRASGTTRP-- 117 Query: 475 SASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELAR-IAGKVPGL 533 G + +IS T + +T+ P R+ R +G PG Sbjct: 118 ---------------GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGT 162 Query: 534 QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593 + R G + L P S P PP E P+ T+EP Sbjct: 163 PSPA---MARRSRAAGTEVGLP---RPAPSARPRPPT---EGPRKSVSSASEHSTTEP-- 211 Query: 594 SPVSSKTESVSDKEDKPPLAPSGGTEGP-EQPPPPCPSQTGSPPVGLIKGEDKDEGPVAE 652 SP + + S +P + P P PS G+P + K +G + Sbjct: 212 SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG--LQ 269 Query: 653 QVKKSTLNPNAKEFNPTK-PLLSVNKSTSTPTSPG-----PRTHSTPSIPVLTAGQS--G 704 ++ + P K+ P PL S +T +P++P P + PS P Q+ Sbjct: 270 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTS 329 Query: 705 LYSPQYI---SYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQP 761 L SP S++P + P P P ++ LPP ++ P Sbjct: 330 LGSPTLQATHSFLPSPPLSPLATPPPQAPPALA----------------LPPLQAPPSPP 373 Query: 762 ASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSN 821 AS PP+ A + A + P++P P A P A P P P Q+ Sbjct: 374 AS-PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 432 Query: 822 PRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTG 881 P + +S P PSA P PQA P A L +P P P Sbjct: 433 PSLAAPPLQVPPSPPASPPMSPSA-TPPPQA-------PPPLAAPPLQLAKPPPQAPPAL 484 Query: 882 SQPQSQHAAPSPVQHQAGQAPH----------LGSGQPQQNLYHPGALTGTPPSLPPGPS 931 + P Q A PSP GQAP L + PQ L PPS P P+ Sbjct: 485 ATPPLQ-ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 543 Query: 932 AQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLL 991 Q+P+ P P ++ +L + AP P P P L Sbjct: 544 LQAPRRP-PTPGPDTSVSGPRLT-----------------LALAPGPPPPPSRSPSSTLS 585 Query: 992 HPPQSHGGPPQGAVPQ------SGVPALSASTPSPYPYIG--HPQGEQPGQAP-----GF 1038 P + + P+ SG +A++P P + HP G AP G Sbjct: 586 GPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGA 645 Query: 1039 PG 1040 PG Sbjct: 646 PG 647 Score = 39.7 bits (91), Expect = 0.015 Identities = 33/123 (26%), Positives = 44/123 (35%), Gaps = 22/123 (17%) Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTS------------PPNGGLPGPLATSAAPPGPPA 53 PLQ P P PP P + PP+ + P + A+PP P+ Sbjct: 365 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 424 Query: 54 AASPCLGPVAAAGSGLRRGAEGILAPQPP--PPQQHQERPGAAAIG--SARGQSTGKGPP 109 A P P + A L+ + P PP PP P A +A K PP Sbjct: 425 ATPPSQAPPSLAAPPLQ------VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 478 Query: 110 QSP 112 Q+P Sbjct: 479 QAP 481 Score = 39.7 bits (91), Expect = 0.015 Identities = 63/290 (21%), Positives = 92/290 (31%), Gaps = 29/290 (10%) Query: 392 PGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPK 451 P P +A +SP A P + +L++P + PP + PP++P Sbjct: 405 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 464 Query: 452 SAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISP---------ASPKISLA 502 A P+ + P P A+ T + S PG SP A+P Sbjct: 465 PLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 524 Query: 503 PTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN 562 P L P P A PG +L G PS SP + Sbjct: 525 PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP--PPPPSRSPSS 582 Query: 563 SLD-----------PFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPP 611 +L P L+ G E G S P + +++ + + PP Sbjct: 583 TLSGPDLAGHSSSATSTPEELRGYDSGPE---GGAAASPPPDAELAACHPAAWSRGPAPP 639 Query: 612 LAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNP 661 LA G P P P TG + + EGP + L+P Sbjct: 640 LA----FRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDP 685 Score = 38.1 bits (87), Expect = 0.045 Identities = 35/110 (31%), Positives = 46/110 (41%), Gaps = 22/110 (20%) Query: 10 PSQPQQPPPTQQAVARRPPGGTSPPNGGLP--GPLATS-AAPPGPPAAASPCLGPVAAAG 66 P+ P QP P + A RPP T P P GPL++S A P P A SP P Sbjct: 257 PAHPSQPKP-KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPP----- 310 Query: 67 SGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK---GPPQSPV 113 + + +P PP Q ++GS Q+T PP SP+ Sbjct: 311 -----SLQTLPSPPATPPSQ-----ATTSLGSPTLQATHSFLPSPPLSPL 350 Score = 37.0 bits (84), Expect = 0.10 Identities = 34/122 (27%), Positives = 48/122 (39%), Gaps = 15/122 (12%) Query: 3 KPQPLQQPSQPQQPPPTQQAVAR---------RPPGGTSPPNGGLPGPLATSAAPPG-PP 52 KP+ LQ PQ PP + A P ++PP+ P L T +PP PP Sbjct: 264 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPP 323 Query: 53 AAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARG-QSTGKGPPQS 111 + A+ LG + + + PPPQ P A A+ + S PP S Sbjct: 324 SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ----APPALALPPLQAPPSPPASPPLS 379 Query: 112 PV 113 P+ Sbjct: 380 PL 381 Score = 37.0 bits (84), Expect = 0.10 Identities = 39/122 (31%), Positives = 48/122 (39%), Gaps = 30/122 (24%) Query: 13 PQQPP--PTQQAVARRPPGGTSPPNGGLPGP---LATSAAPPGPP--AAASPCLGPVAAA 65 P PP PT QA RRPP T P+ + GP LA + PP PP + +S GP A Sbjct: 535 PPSPPASPTLQA-PRRPP--TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 591 Query: 66 GS-----------GLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVF 114 S G G EG A PPP A + + + +GP F Sbjct: 592 HSSSATSTPEELRGYDSGPEGGAAASPPPD---------AELAACHPAAWSRGPAPPLAF 642 Query: 115 EG 116 G Sbjct: 643 RG 644 Score = 33.9 bits (76), Expect = 0.85 Identities = 36/125 (28%), Positives = 43/125 (34%), Gaps = 27/125 (21%) Query: 4 PQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLAT---------SAAPPGPPAA 54 P PL P PP Q PP +PP LP P A+ SA+ P P A Sbjct: 463 PPPLAAPPLQLAKPPPQA-----PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 517 Query: 55 ASPCLGPVAAAGSGLRRGAEGILAPQPP--PPQQHQER-----PGAAAIGSARGQSTGKG 107 P P A L+ + P PP P Q R P + G + G Sbjct: 518 TPPPQAPPVLAAPLLQ------VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 571 Query: 108 PPQSP 112 PP P Sbjct: 572 PPPPP 576 Score = 33.1 bits (74), Expect = 1.4 Identities = 39/143 (27%), Positives = 55/143 (38%), Gaps = 34/143 (23%) Query: 1 MLKPQPLQQPSQPQQPPPTQQ----------AVARRP--------PGGTSPPNGGLPGPL 42 +L P+P P P+ PPP AV R+P G T P + GP Sbjct: 24 LLTPRP---PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT 80 Query: 43 ATSAAPPG-----PPAAASPCLGPVAAAG--SGLRR----GAEG--ILAPQPPPPQQHQE 89 TS P P A + GPV++ G SG R G +G I A + + E Sbjct: 81 RTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE 140 Query: 90 RPGAAAIGSARGQSTGKGPPQSP 112 P +A+ + + T P +P Sbjct: 141 APKRSALSAGARRDTSGPTPGTP 163 Score = 32.0 bits (71), Expect = 3.2 Identities = 30/100 (30%), Positives = 36/100 (36%), Gaps = 12/100 (12%) Query: 10 PSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGL 69 P P PP Q PP PP L P + A+PP P A P A A L Sbjct: 346 PLSPLATPPPQ-----APPALALPP---LQAPPSPPASPPLSPLATPSPQAPNALAVHLL 397 Query: 70 RRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109 + +P P PP Q P A+ S + PP Sbjct: 398 ----QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 433 Score = 31.6 bits (70), Expect = 4.2 Identities = 33/119 (27%), Positives = 43/119 (36%), Gaps = 21/119 (17%) Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPG-P---PAAASPCLGP 61 P+Q P P PP + P +PP+ P PL +PP P P+A P P Sbjct: 408 PVQAPFSPPASPPVSPSAT---PPSQAPPSLAAP-PLQVPPSPPASPPMSPSATPPPQAP 463 Query: 62 VAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGP-------PQSPV 113 A L+ LA PP P A+ S G+ P P SP+ Sbjct: 464 PPLAAPPLQ------LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 516 Score = 31.6 bits (70), Expect = 4.2 Identities = 29/91 (31%), Positives = 34/91 (37%), Gaps = 13/91 (14%) Query: 16 PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEG 75 PPP + A P + P PLA AP G P P GP +A G EG Sbjct: 618 PPPDAELAACHPAAWSRGP----APPLAFRGAP-GAPLPWPPATGPGSADGLCTIYETEG 672 Query: 76 ILAPQPPPPQQHQERPGAAAIGSARGQSTGK 106 P+ PGA G + G S GK Sbjct: 673 --------PESATPAPGALDPGPSPGTSGGK 695 Score = 30.4 bits (67), Expect = 9.4 Identities = 31/126 (24%), Positives = 45/126 (35%), Gaps = 21/126 (16%) Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGP--------PAAASP 57 P P++ +PP + + P TSP PG A+ PGP A + Sbjct: 75 PRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPG-RASGTTRPGPLGQKGLRISAEETV 133 Query: 58 CLGPV------AAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIG------SARGQSTG 105 G +A +G RR G P P + R +G SAR + Sbjct: 134 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 193 Query: 106 KGPPQS 111 +GP +S Sbjct: 194 EGPRKS 199 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 87.4 bits (215), Expect = 6e-17 Identities = 176/733 (24%), Positives = 244/733 (33%), Gaps = 171/733 (23%) Query: 357 REGP-RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRP 415 R GP R S + RP S R P N+SPGP S G G +R P Q+ Sbjct: 76 RAGPTRSAGTSSRNPASRPPASGRGERAPP-AKNTSPGPVSSP-GRASGTTRPGPLGQKG 133 Query: 416 LR---------GAKT-------LSSPSNRP-SGETSVPPPPAVGRMYPPRSPKSAAPAPI 458 LR G T LS+ + R SG T P PA+ R + P P Sbjct: 134 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 193 Query: 459 SASCPEPPI-GSAVPTSSASIPVTSSVS-------DPGVGSISPASPKISLAPTDVKELS 510 ++ P PP G SSAS T+ S G G PAS +S + T + + Sbjct: 194 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253 Query: 511 TKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPR 570 P AR + P ++ K L+ LR PP+ Sbjct: 254 RSGPS--------ARGTPRAPAHPSQPKPKGLQALR---------------------PPQ 284 Query: 571 ILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPS 630 + P+ G L+S P+ +P +PS + Q PP P+ Sbjct: 285 VTP--PRKDAAPALGPLSSSPLATP-----------------SPSAALQS--QAPPTLPA 323 Query: 631 QTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTH 690 S + +A + + +P+A T P S P +P + Sbjct: 324 TPHSSSLTC---------QLATPLPLAPPSPSAPPSLQTLP--------SPPATPPSQAT 366 Query: 691 STPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGS 750 ++ P L A S L SP + P P P ++ Sbjct: 367 TSLGSPTLQATHSFLPSPP---------LSPLATPPPQAPPALA---------------- 401 Query: 751 LPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPS 810 LPP ++ PAS PP+ A + A + P++P P A P A P Sbjct: 402 LPPLQAPPSPPAS-PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 460 Query: 811 QPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHA 870 P P Q+ P + +S P PSA P PQA P A L Sbjct: 461 SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA-TPPPQA-------PPPLAAPPLQL 512 Query: 871 HQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPH----------LGSGQPQQNLYHPGALT 920 +P P P + P Q A PSP GQAP L + PQ L Sbjct: 513 AKPPPQAPPALATPPLQ-ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL 571 Query: 921 GTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHP 980 PPS P P+ Q+P+ P P ++ +L + AP P P Sbjct: 572 QVPPSPPASPTLQAPRRP-PTPGPDTSVSGPRLT-----------------LALAPGPPP 613 Query: 981 GAPHPPQVMLLHPPQSHGGPPQGAVPQ------SGVPALSASTPSPYPYIG--HPQGEQP 1032 P L P + + P+ SG +A++P P + HP Sbjct: 614 PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR 673 Query: 1033 GQAP-----GFPG 1040 G AP G PG Sbjct: 674 GPAPPLAFRGAPG 686 Score = 39.7 bits (91), Expect = 0.015 Identities = 33/123 (26%), Positives = 44/123 (35%), Gaps = 22/123 (17%) Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTS------------PPNGGLPGPLATSAAPPGPPA 53 PLQ P P PP P + PP+ + P + A+PP P+ Sbjct: 404 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 463 Query: 54 AASPCLGPVAAAGSGLRRGAEGILAPQPP--PPQQHQERPGAAAIG--SARGQSTGKGPP 109 A P P + A L+ + P PP PP P A +A K PP Sbjct: 464 ATPPSQAPPSLAAPPLQ------VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 517 Query: 110 QSP 112 Q+P Sbjct: 518 QAP 520 Score = 39.7 bits (91), Expect = 0.015 Identities = 63/290 (21%), Positives = 92/290 (31%), Gaps = 29/290 (10%) Query: 392 PGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPK 451 P P +A +SP A P + +L++P + PP + PP++P Sbjct: 444 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 503 Query: 452 SAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISP---------ASPKISLA 502 A P+ + P P A+ T + S PG SP A+P Sbjct: 504 PLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 563 Query: 503 PTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN 562 P L P P A PG +L G PS SP + Sbjct: 564 PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP--PPPPSRSPSS 621 Query: 563 SLD-----------PFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPP 611 +L P L+ G E G S P + +++ + + PP Sbjct: 622 TLSGPDLAGHSSSATSTPEELRGYDSGPE---GGAAASPPPDAELAACHPAAWSRGPAPP 678 Query: 612 LAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNP 661 LA G P P P TG + + EGP + L+P Sbjct: 679 LA----FRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDP 724 Score = 37.0 bits (84), Expect = 0.10 Identities = 39/122 (31%), Positives = 48/122 (39%), Gaps = 30/122 (24%) Query: 13 PQQPP--PTQQAVARRPPGGTSPPNGGLPGP---LATSAAPPGPP--AAASPCLGPVAAA 65 P PP PT QA RRPP T P+ + GP LA + PP PP + +S GP A Sbjct: 574 PPSPPASPTLQA-PRRPP--TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 630 Query: 66 GS-----------GLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVF 114 S G G EG A PPP A + + + +GP F Sbjct: 631 HSSSATSTPEELRGYDSGPEGGAAASPPPD---------AELAACHPAAWSRGPAPPLAF 681 Query: 115 EG 116 G Sbjct: 682 RG 683 Score = 36.2 bits (82), Expect = 0.17 Identities = 35/124 (28%), Positives = 47/124 (37%), Gaps = 20/124 (16%) Query: 3 KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAA-------- 54 KP+ LQ PQ PP + A P +SP P S APP PA Sbjct: 273 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTC 332 Query: 55 --ASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK---GPP 109 A+P P+A + + +P PP Q ++GS Q+T PP Sbjct: 333 QLATPL--PLAPPSPSAPPSLQTLPSPPATPPSQ-----ATTSLGSPTLQATHSFLPSPP 385 Query: 110 QSPV 113 SP+ Sbjct: 386 LSPL 389 Score = 33.9 bits (76), Expect = 0.85 Identities = 36/125 (28%), Positives = 43/125 (34%), Gaps = 27/125 (21%) Query: 4 PQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLAT---------SAAPPGPPAA 54 P PL P PP Q PP +PP LP P A+ SA+ P P A Sbjct: 502 PPPLAAPPLQLAKPPPQA-----PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 556 Query: 55 ASPCLGPVAAAGSGLRRGAEGILAPQPP--PPQQHQER-----PGAAAIGSARGQSTGKG 107 P P A L+ + P PP P Q R P + G + G Sbjct: 557 TPPPQAPPVLAAPLLQ------VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 610 Query: 108 PPQSP 112 PP P Sbjct: 611 PPPPP 615 Score = 32.0 bits (71), Expect = 3.2 Identities = 30/100 (30%), Positives = 36/100 (36%), Gaps = 12/100 (12%) Query: 10 PSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGL 69 P P PP Q PP PP L P + A+PP P A P A A L Sbjct: 385 PLSPLATPPPQ-----APPALALPP---LQAPPSPPASPPLSPLATPSPQAPNALAVHLL 436 Query: 70 RRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109 + +P P PP Q P A+ S + PP Sbjct: 437 ----QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 472 Score = 31.6 bits (70), Expect = 4.2 Identities = 33/119 (27%), Positives = 43/119 (36%), Gaps = 21/119 (17%) Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPG-P---PAAASPCLGP 61 P+Q P P PP + P +PP+ P PL +PP P P+A P P Sbjct: 447 PVQAPFSPPASPPVSPSAT---PPSQAPPSLAAP-PLQVPPSPPASPPMSPSATPPPQAP 502 Query: 62 VAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGP-------PQSPV 113 A L+ LA PP P A+ S G+ P P SP+ Sbjct: 503 PPLAAPPLQ------LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 555 Score = 31.6 bits (70), Expect = 4.2 Identities = 29/91 (31%), Positives = 34/91 (37%), Gaps = 13/91 (14%) Query: 16 PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEG 75 PPP + A P + P PLA AP G P P GP +A G EG Sbjct: 657 PPPDAELAACHPAAWSRGP----APPLAFRGAP-GAPLPWPPATGPGSADGLCTIYETEG 711 Query: 76 ILAPQPPPPQQHQERPGAAAIGSARGQSTGK 106 P+ PGA G + G S GK Sbjct: 712 --------PESATPAPGALDPGPSPGTSGGK 734 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 81.6 bits (200), Expect = 4e-15 Identities = 142/534 (26%), Positives = 191/534 (35%), Gaps = 89/534 (16%) Query: 561 ENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTES-VSDKEDKPPLAPSGGTE 619 E +DP PP + K ++E DGL M + S + S + K P +P G T Sbjct: 546 EKPVDP-PPFMFKPV----KEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTS 600 Query: 620 GPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKST 679 + S SP D AE VKKS + +P K + Sbjct: 601 PINEDIRS--SGRNSPSAASTSSNDSK----AETVKKSAKKVKEEASSPLKSNKRQREKV 654 Query: 680 STPTSPGPRTHST---------PSIPVLTAGQS---------GLYSPQYISYIPQIHMGP 721 ++ T RT S P+ P G+S G P+ I + P Sbjct: 655 ASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNR-STSP 713 Query: 722 AVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAA 781 ++ +PQ +S QQ + +L P+SAPP GP Sbjct: 714 SIPSPQDNESDSDSSA--QQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP----- 766 Query: 782 TPYSSYIPYNPQQFP-GQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840 TP ++ +P PQ P A QP A P+ PV +Q P + HPQ S P Sbjct: 767 TPSATAVP--PQGSPTASQAPNQPQA--PTAPVPHTHIQQAPAL-----HPQRPPSPHPP 817 Query: 841 QYPSAEQPTPQALYATVHQSYPHHATQ-LHAHQPQPATTPTGSQPQSQHAAPS-----PV 894 +PS P + S P HA LH P P + P QH P P Sbjct: 818 PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGP-PGPHSLQAGPLLQHPGPPQPFGLPP 876 Query: 895 QHQAGQAPHLGSGQ----PQQNLYHPGALTGT----PPS---LPPGPSAQ--------SP 935 Q GQAP LG+ P +L P + + PP LPP P A +P Sbjct: 877 QASQGQAP-LGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP 935 Query: 936 QSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQ 995 P P A H P F+ A++ +++ HP + HPP + L+ PQ Sbjct: 936 IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM--PQ 993 Query: 996 SHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQ------GEQP--GQAPGFPGG 1041 S P A P P L+ S P P HP QP Q P PGG Sbjct: 994 SQPLPSSPAQP----PGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGG 1043 Score = 73.2 bits (178), Expect = 1e-12 Identities = 133/610 (21%), Positives = 211/610 (34%), Gaps = 109/610 (17%) Query: 430 SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVS--DP 487 SG+ S+ + G M RS + PA S PI + +S + P +S S D Sbjct: 567 SGKHSMRTRRSRGSMSTLRSGRKKQPA--SPDGRTSPINEDIRSSGRNSPSAASTSSNDS 624 Query: 488 GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547 ++ ++ K+ + + + ++ + E A + K+ + +E+ + Sbjct: 625 KAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEAD--------RTSSKKTKTQEISR 676 Query: 548 FGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD--GLLTSEPMGSPVSSKTESVSD 605 P+S E + R + +E K++D TS + SP ++++S S Sbjct: 677 --------PNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSS 728 Query: 606 KEDK-----PPL--APSGGTEGPEQPPP---------PCPSQTGSPPVGLIKGEDKDEGP 649 + + PP AP+G T P PP P PS T PP G P Sbjct: 729 AQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQP 788 Query: 650 VAEQV--------KKSTLNPNAKEF-------NPTKPLLSVNKSTSTPTSPGPRTHSTPS 694 A + L+P +P PL + S P++P +H+ P Sbjct: 789 QAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP---SHAQP- 844 Query: 695 IPVLTAGQSGLYS------------PQYISYIPQIHMGPA---VQAPQMYPYPVSNSVPG 739 P+ G G +S PQ PQ G A YP+ S +P Sbjct: 845 -PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH-TSLQLPA 902 Query: 740 QQGKYRGAKG-------------------------SLPPQRSDQHQPASAPPMMQAAAAA 774 Q + + LP ++ +H P + P + A Sbjct: 903 SQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNAN 962 Query: 775 GPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAH-YPSQPVFAPML-QSNPRMLTSGSHPQ 832 PP A P SS ++P P + P + PS P P L QS SHP Sbjct: 963 LPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPP 1022 Query: 833 AIVSSSTPQYPSAEQP-TPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAP 891 + PQ P A+ P P + P +T PA T +QP AA Sbjct: 1023 TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP-------PAGPGTSAQPPCSGAAA 1075 Query: 892 SPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQ 951 S G + L + Q ++ +PP P PS + P A+ A ++ Sbjct: 1076 SGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYK 1135 Query: 952 QLPHGFTNMA 961 L G+ + A Sbjct: 1136 HLDRGYNSCA 1145 Score = 47.0 bits (110), Expect = 1e-04 Identities = 135/639 (21%), Positives = 209/639 (32%), Gaps = 114/639 (17%) Query: 374 PGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSP--SNRPSG 431 P L L HH ++ P P PS SP L ++ L P S+ P+G Sbjct: 967 PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPS--SPAQPPGLTQSQNLPPPPASHPPTG 1024 Query: 432 ETSVPP-PPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPG-- 488 V P PP + P P P P S PP G P +SA P + + + G Sbjct: 1025 LHQVAPQPPFAQHPFVPGGPPPITP-PTCPSTSTPPAG---PGTSAQPPCSGAAASGGSI 1080 Query: 489 VGSISPASPKISLAPTDVKELSTKE----PGRTLEPQ-----------ELARIAGKVPGL 533 G S P + + + + E P R+ P+ + AR + Sbjct: 1081 AGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRG 1140 Query: 534 QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593 N R L + G++ + + E + + +E + KEKE + E Sbjct: 1141 YNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERERER 1200 Query: 594 SPVSSKTESVSDKEDK--PPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVA 651 + S S E + P G P PPP P +G Sbjct: 1201 EAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIG------------- 1247 Query: 652 EQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP--TSPGPRTHS-----TPSIPVLTAGQSG 704 P P L + P SP R H P+ P+L G Sbjct: 1248 ----------------PDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPG 1291 Query: 705 LYSPQYISYIPQIHMGPAVQAPQMYPYPV-SNSVPGQQGKYRGAKG-SLPPQRSDQHQPA 762 LY+ + P ++ ++ + + ++ + R G + P D PA Sbjct: 1292 LYN-----------VDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPA 1340 Query: 763 SAPP--MMQAAAAAGPPLVAATPYSSYIP-YNP---QQFPGQPAMMQPMAHYPSQPVFAP 816 + P + +A PP P++S+ P NP ++ ++P YP + Sbjct: 1341 ANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAER 1400 Query: 817 MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQP- 875 + LTS + + + TP H + H + LH HQ P Sbjct: 1401 IHAERMASLTSDPLARLQMFNVTPH----------------HHQHSHIHSHLHLHQQDPL 1444 Query: 876 ---ATTPTGSQPQSQHAAP--SPVQHQAGQAPHLGSGQP---QQNLYHPGALTGTPPSL- 926 + P A P + + G P+ GQP + L HP T P L Sbjct: 1445 HQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLP 1504 Query: 927 ----PPGPSAQSPQSSFPQPAAVYAI-HHQQLPHGFTNM 960 PP +A Q+ Q A + + QQ HG +M Sbjct: 1505 GAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHGHPHM 1543 Score = 45.1 bits (105), Expect = 4e-04 Identities = 39/134 (29%), Positives = 51/134 (38%), Gaps = 32/134 (23%) Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNG-----------------GLPGPL-- 42 L PQ PS P QPP Q+ PP + PP G G P P+ Sbjct: 990 LMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITP 1049 Query: 43 ----ATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGS 98 +TS P GP +A P AA+G + G+ P P Q +E A+ Sbjct: 1050 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSS-----CPLPTVQIKEE----ALDD 1100 Query: 99 ARGQSTGKGPPQSP 112 A + PP+SP Sbjct: 1101 AEEPESPPPPPRSP 1114 Score = 41.2 bits (95), Expect = 0.005 Identities = 92/374 (24%), Positives = 125/374 (33%), Gaps = 82/374 (21%) Query: 371 GGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS 430 G P SS PP P +PGP A + P +G+ T S N+P Sbjct: 746 GVTPAPSSAPPGTPQL---PTPGPTPSATAV-------------PPQGSPTASQAPNQPQ 789 Query: 431 GETSVPPPPAVGR---MYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDP 487 T+ P + + ++P R P +P P P PP+ T SA P S + P Sbjct: 790 APTAPVPHTHIQQAPALHPQRPP---SPHPPPHPSPHPPLQPL--TGSAGQPSAPSHAQP 844 Query: 488 GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547 + P P A ++ +P L PQ G+ P + + L+ Sbjct: 845 PLHGQGPPGPHSLQAGPLLQHPGPPQP-FGLPPQ---ASQGQAPLGTSPAAAYPHTSLQL 900 Query: 548 FGAQFKLQPSSSP-ENSLDPFP-------------------PRILKEEPK---GKEKEVD 584 +Q LQ P E L P P P+ K P ++ Sbjct: 901 PASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 960 Query: 585 GLLTSEPMGSPVSSKTESVSDKEDKPPL--------------APSGGTEGPEQPPPPCPS 630 L P P+SS + PPL P G T+ PPPP Sbjct: 961 ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP--- 1017 Query: 631 QTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTH 690 PP GL + + P A+ P PT P STSTP + GP T Sbjct: 1018 -ASHPPTGL--HQVAPQPPFAQHPFVPGGPPPITP--PTCP------STSTPPA-GPGTS 1065 Query: 691 STPSIPVLTAGQSG 704 + P P A SG Sbjct: 1066 AQP--PCSGAAASG 1077 Score = 38.9 bits (89), Expect = 0.026 Identities = 38/118 (32%), Positives = 46/118 (38%), Gaps = 10/118 (8%) Query: 4 PQPLQQPSQPQQP----PPT--QQAVA---RRPPGGTSPPNGGLPGPLATSAAPPGPPAA 54 P Q P+QPQ P P T QQA A +RPP PP+ PL G P+A Sbjct: 779 PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSA 838 Query: 55 ASPCLGPVAAAG-SGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111 S P+ G G G L P PPQ P A+ + G S P + Sbjct: 839 PSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHT 896 Score = 37.0 bits (84), Expect = 0.10 Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 6/110 (5%) Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAA 65 P Q ++ QQ + + P P G P P S+APPG P +P P A A Sbjct: 716 PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP---SSAPPGTPQLPTPGPTPSATA 772 Query: 66 --GSGLRRGAEGILAPQ-PPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112 G ++ PQ P P H A A+ R S P SP Sbjct: 773 VPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP 822 Score = 36.6 bits (83), Expect = 0.13 Identities = 30/111 (27%), Positives = 38/111 (34%), Gaps = 7/111 (6%) Query: 9 QPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSG 68 QP Q P A + PPG P G P P AT+ P G P A+ P A Sbjct: 737 QPPALQAPTGVTPAPSSAPPGTPQLPTPG-PTPSATAVPPQGSPTASQAPNQPQAPTAPV 795 Query: 69 LRRGAEGILA------PQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPV 113 + A P P PP P + + GQ + Q P+ Sbjct: 796 PHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL 846 Score = 32.3 bits (72), Expect = 2.5 Identities = 33/111 (29%), Positives = 42/111 (37%), Gaps = 15/111 (13%) Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61 L P PL P + PP T P PP+ P P + +A P PPA L P Sbjct: 918 LPPAPLAMP-HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPA-----LKP 971 Query: 62 VAAAGSGLRRGAEGILAPQPPPPQ---QHQERPGAAAIGSARGQSTGKGPP 109 +++ + A PPP Q Q Q P + A QS PP Sbjct: 972 LSSLSTHHPPSA------HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 1016 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 81.6 bits (200), Expect = 4e-15 Identities = 142/534 (26%), Positives = 191/534 (35%), Gaps = 89/534 (16%) Query: 561 ENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTES-VSDKEDKPPLAPSGGTE 619 E +DP PP + K ++E DGL M + S + S + K P +P G T Sbjct: 546 EKPVDP-PPFMFKPV----KEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTS 600 Query: 620 GPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKST 679 + S SP D AE VKKS + +P K + Sbjct: 601 PINEDIRS--SGRNSPSAASTSSNDSK----AETVKKSAKKVKEEASSPLKSNKRQREKV 654 Query: 680 STPTSPGPRTHST---------PSIPVLTAGQS---------GLYSPQYISYIPQIHMGP 721 ++ T RT S P+ P G+S G P+ I + P Sbjct: 655 ASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNR-STSP 713 Query: 722 AVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAA 781 ++ +PQ +S QQ + +L P+SAPP GP Sbjct: 714 SIPSPQDNESDSDSSA--QQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP----- 766 Query: 782 TPYSSYIPYNPQQFP-GQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840 TP ++ +P PQ P A QP A P+ PV +Q P + HPQ S P Sbjct: 767 TPSATAVP--PQGSPTASQAPNQPQA--PTAPVPHTHIQQAPAL-----HPQRPPSPHPP 817 Query: 841 QYPSAEQPTPQALYATVHQSYPHHATQ-LHAHQPQPATTPTGSQPQSQHAAPS-----PV 894 +PS P + S P HA LH P P + P QH P P Sbjct: 818 PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGP-PGPHSLQAGPLLQHPGPPQPFGLPP 876 Query: 895 QHQAGQAPHLGSGQ----PQQNLYHPGALTGT----PPS---LPPGPSAQ--------SP 935 Q GQAP LG+ P +L P + + PP LPP P A +P Sbjct: 877 QASQGQAP-LGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP 935 Query: 936 QSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQ 995 P P A H P F+ A++ +++ HP + HPP + L+ PQ Sbjct: 936 IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM--PQ 993 Query: 996 SHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQ------GEQP--GQAPGFPGG 1041 S P A P P L+ S P P HP QP Q P PGG Sbjct: 994 SQPLPSSPAQP----PGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGG 1043 Score = 73.2 bits (178), Expect = 1e-12 Identities = 133/610 (21%), Positives = 211/610 (34%), Gaps = 109/610 (17%) Query: 430 SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVS--DP 487 SG+ S+ + G M RS + PA S PI + +S + P +S S D Sbjct: 567 SGKHSMRTRRSRGSMSTLRSGRKKQPA--SPDGRTSPINEDIRSSGRNSPSAASTSSNDS 624 Query: 488 GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547 ++ ++ K+ + + + ++ + E A + K+ + +E+ + Sbjct: 625 KAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEAD--------RTSSKKTKTQEISR 676 Query: 548 FGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD--GLLTSEPMGSPVSSKTESVSD 605 P+S E + R + +E K++D TS + SP ++++S S Sbjct: 677 --------PNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSS 728 Query: 606 KEDK-----PPL--APSGGTEGPEQPPP---------PCPSQTGSPPVGLIKGEDKDEGP 649 + + PP AP+G T P PP P PS T PP G P Sbjct: 729 AQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQP 788 Query: 650 VAEQV--------KKSTLNPNAKEF-------NPTKPLLSVNKSTSTPTSPGPRTHSTPS 694 A + L+P +P PL + S P++P +H+ P Sbjct: 789 QAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP---SHAQP- 844 Query: 695 IPVLTAGQSGLYS------------PQYISYIPQIHMGPA---VQAPQMYPYPVSNSVPG 739 P+ G G +S PQ PQ G A YP+ S +P Sbjct: 845 -PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH-TSLQLPA 902 Query: 740 QQGKYRGAKG-------------------------SLPPQRSDQHQPASAPPMMQAAAAA 774 Q + + LP ++ +H P + P + A Sbjct: 903 SQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNAN 962 Query: 775 GPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAH-YPSQPVFAPML-QSNPRMLTSGSHPQ 832 PP A P SS ++P P + P + PS P P L QS SHP Sbjct: 963 LPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPP 1022 Query: 833 AIVSSSTPQYPSAEQP-TPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAP 891 + PQ P A+ P P + P +T PA T +QP AA Sbjct: 1023 TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP-------PAGPGTSAQPPCSGAAA 1075 Query: 892 SPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQ 951 S G + L + Q ++ +PP P PS + P A+ A ++ Sbjct: 1076 SGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYK 1135 Query: 952 QLPHGFTNMA 961 L G+ + A Sbjct: 1136 HLDRGYNSCA 1145 Score = 47.0 bits (110), Expect = 1e-04 Identities = 135/639 (21%), Positives = 209/639 (32%), Gaps = 114/639 (17%) Query: 374 PGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSP--SNRPSG 431 P L L HH ++ P P PS SP L ++ L P S+ P+G Sbjct: 967 PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPS--SPAQPPGLTQSQNLPPPPASHPPTG 1024 Query: 432 ETSVPP-PPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPG-- 488 V P PP + P P P P S PP G P +SA P + + + G Sbjct: 1025 LHQVAPQPPFAQHPFVPGGPPPITP-PTCPSTSTPPAG---PGTSAQPPCSGAAASGGSI 1080 Query: 489 VGSISPASPKISLAPTDVKELSTKE----PGRTLEPQ-----------ELARIAGKVPGL 533 G S P + + + + E P R+ P+ + AR + Sbjct: 1081 AGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRG 1140 Query: 534 QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593 N R L + G++ + + E + + +E + KEKE + E Sbjct: 1141 YNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERERER 1200 Query: 594 SPVSSKTESVSDKEDK--PPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVA 651 + S S E + P G P PPP P +G Sbjct: 1201 EAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIG------------- 1247 Query: 652 EQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP--TSPGPRTHS-----TPSIPVLTAGQSG 704 P P L + P SP R H P+ P+L G Sbjct: 1248 ----------------PDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPG 1291 Query: 705 LYSPQYISYIPQIHMGPAVQAPQMYPYPV-SNSVPGQQGKYRGAKG-SLPPQRSDQHQPA 762 LY+ + P ++ ++ + + ++ + R G + P D PA Sbjct: 1292 LYN-----------VDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPA 1340 Query: 763 SAPP--MMQAAAAAGPPLVAATPYSSYIP-YNP---QQFPGQPAMMQPMAHYPSQPVFAP 816 + P + +A PP P++S+ P NP ++ ++P YP + Sbjct: 1341 ANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAER 1400 Query: 817 MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQP- 875 + LTS + + + TP H + H + LH HQ P Sbjct: 1401 IHAERMASLTSDPLARLQMFNVTPH----------------HHQHSHIHSHLHLHQQDPL 1444 Query: 876 ---ATTPTGSQPQSQHAAP--SPVQHQAGQAPHLGSGQP---QQNLYHPGALTGTPPSL- 926 + P A P + + G P+ GQP + L HP T P L Sbjct: 1445 HQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLP 1504 Query: 927 ----PPGPSAQSPQSSFPQPAAVYAI-HHQQLPHGFTNM 960 PP +A Q+ Q A + + QQ HG +M Sbjct: 1505 GAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHGHPHM 1543 Score = 45.1 bits (105), Expect = 4e-04 Identities = 39/134 (29%), Positives = 51/134 (38%), Gaps = 32/134 (23%) Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNG-----------------GLPGPL-- 42 L PQ PS P QPP Q+ PP + PP G G P P+ Sbjct: 990 LMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITP 1049 Query: 43 ----ATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGS 98 +TS P GP +A P AA+G + G+ P P Q +E A+ Sbjct: 1050 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSS-----CPLPTVQIKEE----ALDD 1100 Query: 99 ARGQSTGKGPPQSP 112 A + PP+SP Sbjct: 1101 AEEPESPPPPPRSP 1114 Score = 41.2 bits (95), Expect = 0.005 Identities = 92/374 (24%), Positives = 125/374 (33%), Gaps = 82/374 (21%) Query: 371 GGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS 430 G P SS PP P +PGP A + P +G+ T S N+P Sbjct: 746 GVTPAPSSAPPGTPQL---PTPGPTPSATAV-------------PPQGSPTASQAPNQPQ 789 Query: 431 GETSVPPPPAVGR---MYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDP 487 T+ P + + ++P R P +P P P PP+ T SA P S + P Sbjct: 790 APTAPVPHTHIQQAPALHPQRPP---SPHPPPHPSPHPPLQPL--TGSAGQPSAPSHAQP 844 Query: 488 GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547 + P P A ++ +P L PQ G+ P + + L+ Sbjct: 845 PLHGQGPPGPHSLQAGPLLQHPGPPQP-FGLPPQ---ASQGQAPLGTSPAAAYPHTSLQL 900 Query: 548 FGAQFKLQPSSSP-ENSLDPFP-------------------PRILKEEPK---GKEKEVD 584 +Q LQ P E L P P P+ K P ++ Sbjct: 901 PASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 960 Query: 585 GLLTSEPMGSPVSSKTESVSDKEDKPPL--------------APSGGTEGPEQPPPPCPS 630 L P P+SS + PPL P G T+ PPPP Sbjct: 961 ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP--- 1017 Query: 631 QTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTH 690 PP GL + + P A+ P PT P STSTP + GP T Sbjct: 1018 -ASHPPTGL--HQVAPQPPFAQHPFVPGGPPPITP--PTCP------STSTPPA-GPGTS 1065 Query: 691 STPSIPVLTAGQSG 704 + P P A SG Sbjct: 1066 AQP--PCSGAAASG 1077 Score = 38.9 bits (89), Expect = 0.026 Identities = 38/118 (32%), Positives = 46/118 (38%), Gaps = 10/118 (8%) Query: 4 PQPLQQPSQPQQP----PPT--QQAVA---RRPPGGTSPPNGGLPGPLATSAAPPGPPAA 54 P Q P+QPQ P P T QQA A +RPP PP+ PL G P+A Sbjct: 779 PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSA 838 Query: 55 ASPCLGPVAAAG-SGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111 S P+ G G G L P PPQ P A+ + G S P + Sbjct: 839 PSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHT 896 Score = 37.0 bits (84), Expect = 0.10 Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 6/110 (5%) Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAA 65 P Q ++ QQ + + P P G P P S+APPG P +P P A A Sbjct: 716 PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP---SSAPPGTPQLPTPGPTPSATA 772 Query: 66 --GSGLRRGAEGILAPQ-PPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112 G ++ PQ P P H A A+ R S P SP Sbjct: 773 VPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP 822 Score = 36.6 bits (83), Expect = 0.13 Identities = 30/111 (27%), Positives = 38/111 (34%), Gaps = 7/111 (6%) Query: 9 QPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSG 68 QP Q P A + PPG P G P P AT+ P G P A+ P A Sbjct: 737 QPPALQAPTGVTPAPSSAPPGTPQLPTPG-PTPSATAVPPQGSPTASQAPNQPQAPTAPV 795 Query: 69 LRRGAEGILA------PQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPV 113 + A P P PP P + + GQ + Q P+ Sbjct: 796 PHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL 846 Score = 32.3 bits (72), Expect = 2.5 Identities = 33/111 (29%), Positives = 42/111 (37%), Gaps = 15/111 (13%) Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61 L P PL P + PP T P PP+ P P + +A P PPA L P Sbjct: 918 LPPAPLAMP-HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPA-----LKP 971 Query: 62 VAAAGSGLRRGAEGILAPQPPPPQ---QHQERPGAAAIGSARGQSTGKGPP 109 +++ + A PPP Q Q Q P + A QS PP Sbjct: 972 LSSLSTHHPPSA------HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 1016 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 80.1 bits (196), Expect = 1e-14 Identities = 137/518 (26%), Positives = 184/518 (35%), Gaps = 84/518 (16%) Query: 577 KGKEKEVDGLLTSEPMGSPVSSKTES-VSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSP 635 K ++E DGL M + S + S + K P +P G T + S SP Sbjct: 3 KPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRS--SGRNSP 60 Query: 636 PVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHST--- 692 D AE VKKS + +P K + ++ T RT S Sbjct: 61 SAASTSSNDSK----AETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTK 116 Query: 693 ------PSIPVLTAGQS---------GLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSV 737 P+ P G+S G P+ I + P++ +PQ +S Sbjct: 117 TQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNR-STSPSIPSPQDNESDSDSSA 175 Query: 738 PGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFP- 796 QQ + +L P+SAPP GP TP ++ +P PQ P Sbjct: 176 --QQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP-----TPSATAVP--PQGSPT 226 Query: 797 GQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYAT 856 A QP A P+ PV +Q P + HPQ S P +PS P + Sbjct: 227 ASQAPNQPQA--PTAPVPHTHIQQAPAL-----HPQRPPSPHPPPHPSPHPPLQPLTGSA 279 Query: 857 VHQSYPHHATQ-LHAHQPQPATTPTGSQPQSQHAAPS-----PVQHQAGQAPHLGSGQ-- 908 S P HA LH P P + P QH P P Q GQAP LG+ Sbjct: 280 GQPSAPSHAQPPLHGQGP-PGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAP-LGTSPAA 337 Query: 909 --PQQNLYHPGALTGT----PPS---LPPGPSAQ--------SPQSSFPQPAAVYAIHHQ 951 P +L P + + PP LPP P A +P P P A H Sbjct: 338 AYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHL 397 Query: 952 QLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVP 1011 P F+ A++ +++ HP + HPP + L+ PQS P A P P Sbjct: 398 SGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM--PQSQPLPSSPAQP----P 451 Query: 1012 ALSASTPSPYPYIGHPQ------GEQP--GQAPGFPGG 1041 L+ S P P HP QP Q P PGG Sbjct: 452 GLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGG 489 Score = 73.2 bits (178), Expect = 1e-12 Identities = 133/610 (21%), Positives = 211/610 (34%), Gaps = 109/610 (17%) Query: 430 SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVS--DP 487 SG+ S+ + G M RS + PA S PI + +S + P +S S D Sbjct: 13 SGKHSMRTRRSRGSMSTLRSGRKKQPA--SPDGRTSPINEDIRSSGRNSPSAASTSSNDS 70 Query: 488 GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547 ++ ++ K+ + + + ++ + E A + K+ + +E+ + Sbjct: 71 KAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEAD--------RTSSKKTKTQEISR 122 Query: 548 FGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD--GLLTSEPMGSPVSSKTESVSD 605 P+S E + R + +E K++D TS + SP ++++S S Sbjct: 123 --------PNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSS 174 Query: 606 KEDK-----PPL--APSGGTEGPEQPPP---------PCPSQTGSPPVGLIKGEDKDEGP 649 + + PP AP+G T P PP P PS T PP G P Sbjct: 175 AQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQP 234 Query: 650 VAEQV--------KKSTLNPNAKEF-------NPTKPLLSVNKSTSTPTSPGPRTHSTPS 694 A + L+P +P PL + S P++P +H+ P Sbjct: 235 QAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP---SHAQP- 290 Query: 695 IPVLTAGQSGLYS------------PQYISYIPQIHMGPA---VQAPQMYPYPVSNSVPG 739 P+ G G +S PQ PQ G A YP+ S +P Sbjct: 291 -PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH-TSLQLPA 348 Query: 740 QQGKYRGAKG-------------------------SLPPQRSDQHQPASAPPMMQAAAAA 774 Q + + LP ++ +H P + P + A Sbjct: 349 SQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNAN 408 Query: 775 GPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAH-YPSQPVFAPML-QSNPRMLTSGSHPQ 832 PP A P SS ++P P + P + PS P P L QS SHP Sbjct: 409 LPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPP 468 Query: 833 AIVSSSTPQYPSAEQP-TPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAP 891 + PQ P A+ P P + P +T PA T +QP AA Sbjct: 469 TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP-------PAGPGTSAQPPCSGAAA 521 Query: 892 SPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQ 951 S G + L + Q ++ +PP P PS + P A+ A ++ Sbjct: 522 SGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYK 581 Query: 952 QLPHGFTNMA 961 L G+ + A Sbjct: 582 HLDRGYNSCA 591 Score = 47.0 bits (110), Expect = 1e-04 Identities = 135/639 (21%), Positives = 209/639 (32%), Gaps = 114/639 (17%) Query: 374 PGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSP--SNRPSG 431 P L L HH ++ P P PS SP L ++ L P S+ P+G Sbjct: 413 PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPS--SPAQPPGLTQSQNLPPPPASHPPTG 470 Query: 432 ETSVPP-PPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPG-- 488 V P PP + P P P P S PP G P +SA P + + + G Sbjct: 471 LHQVAPQPPFAQHPFVPGGPPPITP-PTCPSTSTPPAG---PGTSAQPPCSGAAASGGSI 526 Query: 489 VGSISPASPKISLAPTDVKELSTKE----PGRTLEPQ-----------ELARIAGKVPGL 533 G S P + + + + E P R+ P+ + AR + Sbjct: 527 AGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRG 586 Query: 534 QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593 N R L + G++ + + E + + +E + KEKE + E Sbjct: 587 YNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERERER 646 Query: 594 SPVSSKTESVSDKEDK--PPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVA 651 + S S E + P G P PPP P +G Sbjct: 647 EAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIG------------- 693 Query: 652 EQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP--TSPGPRTHS-----TPSIPVLTAGQSG 704 P P L + P SP R H P+ P+L G Sbjct: 694 ----------------PDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPG 737 Query: 705 LYSPQYISYIPQIHMGPAVQAPQMYPYPV-SNSVPGQQGKYRGAKG-SLPPQRSDQHQPA 762 LY+ + P ++ ++ + + ++ + R G + P D PA Sbjct: 738 LYN-----------VDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPA 786 Query: 763 SAPP--MMQAAAAAGPPLVAATPYSSYIP-YNP---QQFPGQPAMMQPMAHYPSQPVFAP 816 + P + +A PP P++S+ P NP ++ ++P YP + Sbjct: 787 ANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAER 846 Query: 817 MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQP- 875 + LTS + + + TP H + H + LH HQ P Sbjct: 847 IHAERMASLTSDPLARLQMFNVTPH----------------HHQHSHIHSHLHLHQQDPL 890 Query: 876 ---ATTPTGSQPQSQHAAP--SPVQHQAGQAPHLGSGQP---QQNLYHPGALTGTPPSL- 926 + P A P + + G P+ GQP + L HP T P L Sbjct: 891 HQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLP 950 Query: 927 ----PPGPSAQSPQSSFPQPAAVYAI-HHQQLPHGFTNM 960 PP +A Q+ Q A + + QQ HG +M Sbjct: 951 GAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHGHPHM 989 Score = 45.1 bits (105), Expect = 4e-04 Identities = 39/134 (29%), Positives = 51/134 (38%), Gaps = 32/134 (23%) Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNG-----------------GLPGPL-- 42 L PQ PS P QPP Q+ PP + PP G G P P+ Sbjct: 436 LMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITP 495 Query: 43 ----ATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGS 98 +TS P GP +A P AA+G + G+ P P Q +E A+ Sbjct: 496 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSS-----CPLPTVQIKEE----ALDD 546 Query: 99 ARGQSTGKGPPQSP 112 A + PP+SP Sbjct: 547 AEEPESPPPPPRSP 560 Score = 41.2 bits (95), Expect = 0.005 Identities = 92/374 (24%), Positives = 125/374 (33%), Gaps = 82/374 (21%) Query: 371 GGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS 430 G P SS PP P +PGP A + P +G+ T S N+P Sbjct: 192 GVTPAPSSAPPGTPQL---PTPGPTPSATAV-------------PPQGSPTASQAPNQPQ 235 Query: 431 GETSVPPPPAVGR---MYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDP 487 T+ P + + ++P R P +P P P PP+ T SA P S + P Sbjct: 236 APTAPVPHTHIQQAPALHPQRPP---SPHPPPHPSPHPPLQPL--TGSAGQPSAPSHAQP 290 Query: 488 GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547 + P P A ++ +P L PQ G+ P + + L+ Sbjct: 291 PLHGQGPPGPHSLQAGPLLQHPGPPQP-FGLPPQ---ASQGQAPLGTSPAAAYPHTSLQL 346 Query: 548 FGAQFKLQPSSSP-ENSLDPFP-------------------PRILKEEPK---GKEKEVD 584 +Q LQ P E L P P P+ K P ++ Sbjct: 347 PASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 406 Query: 585 GLLTSEPMGSPVSSKTESVSDKEDKPPL--------------APSGGTEGPEQPPPPCPS 630 L P P+SS + PPL P G T+ PPPP Sbjct: 407 ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP--- 463 Query: 631 QTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTH 690 PP GL + + P A+ P PT P STSTP + GP T Sbjct: 464 -ASHPPTGL--HQVAPQPPFAQHPFVPGGPPPITP--PTCP------STSTPPA-GPGTS 511 Query: 691 STPSIPVLTAGQSG 704 + P P A SG Sbjct: 512 AQP--PCSGAAASG 523 Score = 38.9 bits (89), Expect = 0.026 Identities = 38/118 (32%), Positives = 46/118 (38%), Gaps = 10/118 (8%) Query: 4 PQPLQQPSQPQQP----PPT--QQAVA---RRPPGGTSPPNGGLPGPLATSAAPPGPPAA 54 P Q P+QPQ P P T QQA A +RPP PP+ PL G P+A Sbjct: 225 PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSA 284 Query: 55 ASPCLGPVAAAG-SGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111 S P+ G G G L P PPQ P A+ + G S P + Sbjct: 285 PSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHT 342 Score = 37.0 bits (84), Expect = 0.10 Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 6/110 (5%) Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAA 65 P Q ++ QQ + + P P G P P S+APPG P +P P A A Sbjct: 162 PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP---SSAPPGTPQLPTPGPTPSATA 218 Query: 66 --GSGLRRGAEGILAPQ-PPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112 G ++ PQ P P H A A+ R S P SP Sbjct: 219 VPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP 268 Score = 36.6 bits (83), Expect = 0.13 Identities = 30/111 (27%), Positives = 38/111 (34%), Gaps = 7/111 (6%) Query: 9 QPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSG 68 QP Q P A + PPG P G P P AT+ P G P A+ P A Sbjct: 183 QPPALQAPTGVTPAPSSAPPGTPQLPTPG-PTPSATAVPPQGSPTASQAPNQPQAPTAPV 241 Query: 69 LRRGAEGILA------PQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPV 113 + A P P PP P + + GQ + Q P+ Sbjct: 242 PHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL 292 Score = 32.3 bits (72), Expect = 2.5 Identities = 33/111 (29%), Positives = 42/111 (37%), Gaps = 15/111 (13%) Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61 L P PL P + PP T P PP+ P P + +A P PPA L P Sbjct: 364 LPPAPLAMP-HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPA-----LKP 417 Query: 62 VAAAGSGLRRGAEGILAPQPPPPQ---QHQERPGAAAIGSARGQSTGKGPP 109 +++ + A PPP Q Q Q P + A QS PP Sbjct: 418 LSSLSTHHPPSA------HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 462 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 79.7 bits (195), Expect = 1e-14 Identities = 162/676 (23%), Positives = 235/676 (34%), Gaps = 158/676 (23%) Query: 375 GLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETS 434 GL++ G SP + G+ S++S + +R + A +S P G S Sbjct: 15 GLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQI--AAVMSRAQGLPKG--S 70 Query: 435 VPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISP 494 VPP A SP + +S P P S P DPG P Sbjct: 71 VPPAAA-------ESPSMHRKQELDSSHP--------PKQSGRPP------DPG----RP 105 Query: 495 ASPKISLA-PTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKF----G 549 A P +S + TD K PGR+ P ++ L+ + R L+E K G Sbjct: 106 AQPGLSKSRTTDTFRSEQKLPGRS--PSTIS--------LKESKSRTDLKEEHKSSMMPG 155 Query: 550 AQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKED- 608 ++ S+ + ++ F P L + + ++E ++K + V KE Sbjct: 156 FLSEVNALSAVSSVVNKFNPFDLISDSEASQEE--------------TTKKQKVVQKEQG 201 Query: 609 ------KPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPN 662 KPPL +QPP P P Q G G D P+ + +++ Sbjct: 202 KPEGIIKPPLQ--------QQPPKPIPKQQG-------PGRD----PLQQDGTPKSISSQ 242 Query: 663 AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722 E ++P K PT H+ +P+ Q + PQ Sbjct: 243 QPEKIKSQP-PGTGKPIQGPTQTPQTDHA--KLPL-----------QRDASRPQTKQADI 288 Query: 723 VQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAAT 782 V+ + P S S P Q G + P ++ QP A P Q + P +A Sbjct: 289 VRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGH-EKSQPGPAKPPAQPSGLTKP--LAQQ 345 Query: 783 PYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQY 842 P + P P PG ++P P+ + P +GS + Sbjct: 346 PGTVKPPVQP---PG-----------TTKPPAQPLGPAKPPAQQTGS-----------EK 380 Query: 843 PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAG-QA 901 PS+EQP P+AL + P + A QP PA PT Q P P+ Q G Q+ Sbjct: 381 PSSEQPGPKAL------AQPPGVGKTPAQQPGPAKPPT-----QQVGTPKPLAQQPGLQS 429 Query: 902 PHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMA 961 P G + + PG G P+ GP S Q + P QLP Sbjct: 430 PAKAPGPTKTPVQQPG--PGKIPAQQAGPGKTSAQQTGPTKPP------SQLP------G 475 Query: 962 HVTQAHVQTGITAAPPPHPGAPHPP--QVMLLHPPQSHGGPPQGAVPQSGVPALSASTPS 1019 Q G PP PG+ PP Q PP GP + + Q G S PS Sbjct: 476 PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPG----STKPPS 531 Query: 1020 PYPYIGHPQGEQPGQA 1035 P P +QP A Sbjct: 532 QQPGSAKPSAQQPSPA 547 Score = 68.9 bits (167), Expect = 2e-11 Identities = 157/690 (22%), Positives = 231/690 (33%), Gaps = 123/690 (17%) Query: 333 QGSGRESPSLASREGKYIPLPQRVREGPR---GGVRCSSSRGG-------RPGLSSLPPR 382 Q +G E PS K + P V + P G + + + G +PGL S P + Sbjct: 374 QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQS-PAK 432 Query: 383 --GPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGET--SVPPP 438 GP PGPG + GP + S + P + L P+ P + + PPP Sbjct: 433 APGPTKTPVQQPGPG-KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPP 491 Query: 439 PAVGRMYPP-----------RSPKSAAPAPISASCPEPPI---GSAVPTSSASIPV---- 480 G PP + P A P+P +PP GSA P++ P Sbjct: 492 QQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSA 551 Query: 481 ---TSSVSDPGVG------SISPAS--------PK--ISLAPTDVKELSTKEPGRTLEPQ 521 T VS G G ++SP++ PK L T L E Sbjct: 552 QQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCT 611 Query: 522 ELARIAGKVPGLQNEQKRFQLEELRKFGAQFK------LQP-SSSPENSLDPFP----PR 570 E + G +++E Q K L P SSP+ L P Sbjct: 612 ECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSA 671 Query: 571 ILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEG-----PEQPP 625 + K P+ ++ TS + + + PPL G +QPP Sbjct: 672 VSKSSPQPQQ-------TSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724 Query: 626 PPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSP 685 +PP ++D+ PVA+ K K PT L+S + +T+ P P Sbjct: 725 EADSLSKPAPPKEPSVPSEQDKAPVADDKPK-----QPKMVKPTTDLVSSSSATTKPDIP 779 Query: 686 GPRTHS------TPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPG 739 + S TP + +A S + P P A+ P +S+ PG Sbjct: 780 SSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSP--FDSKAIPRPASDSKIISH--PG 835 Query: 740 QQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQP 799 + +G K P Q+ + +P A M A P P S P P+ GQ Sbjct: 836 PSSESKGQKQVDPVQKKE--EPKKAQTKMSPKPDAKP-----MPKGSPTPPGPRPTAGQT 888 Query: 800 AMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQ 859 + P + QS L GS ++ + P+ Q T Sbjct: 889 VPTPQQSPKPQE-------QSRRFSLNLGS-----ITDAPKSQPTTPQETVTGKLFGFGA 936 Query: 860 SYPHHATQL--HAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPG 917 S A+ L A QP P + P Q AP+P Q Q P +GQ Sbjct: 937 SIFSQASNLISTAGQPGPHSQSGPGAPMKQ--APAPSQPPTSQGPPKSTGQ--------- 985 Query: 918 ALTGTPPSLPPGPSAQSPQSSFPQPAAVYA 947 A S+P ++P + +P A A Sbjct: 986 APPAPAKSIPVKKETKAPAAEKLEPKAEQA 1015 Score = 57.4 bits (137), Expect = 7e-08 Identities = 142/638 (22%), Positives = 197/638 (30%), Gaps = 114/638 (17%) Query: 405 PSRMSPKAQRPLRG-----AKTLSSPSNRPSGETSVPP---PPAVGRMYPPRSPKSAAPA 456 P + PK Q P R S S +P S PP P G P++ + P Sbjct: 215 PPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPL 274 Query: 457 PISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGR 516 AS P+ V S P S S P + +P P + + +P Sbjct: 275 QRDASRPQTKQADIVRGESVK-PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP-- 331 Query: 517 TLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEP 576 +P L + + PG + Q K AQ L P+ P P + P Sbjct: 332 PAQPSGLTKPLAQQPG--TVKPPVQPPGTTKPPAQ-PLGPAKPPAQQTGSEKPSSEQPGP 388 Query: 577 KGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPP 636 K + T P T+ V + PLA G + P + P P + P Sbjct: 389 KALAQPPGVGKTPAQQPGPAKPPTQQVGTPK---PLAQQPGLQSPAKAPGPTKTPVQQPG 445 Query: 637 VGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIP 696 G I + G +A++ PTKP + PGP Sbjct: 446 PGKIPAQQAGPG-----------KTSAQQTGPTKPPSQL---------PGP--------- 476 Query: 697 VLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRS 756 + P GPA PQ P S P QQ GS P Sbjct: 477 ---------------AKPPPQQPGPAKPPPQQ---PGSAKPPSQQ------PGSTKP--- 509 Query: 757 DQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAP 816 QP A P Q + PP QP +P A PS + Sbjct: 510 PPQQPGPAKPSPQQPGSTKPP------------------SQQPGSAKPSAQQPSPAKPSA 551 Query: 817 MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPA 876 + P T P + S PSA+QP Q L T+ + T+L H P+ A Sbjct: 552 QQSTKPVSQTGSGKPLQPPTVS----PSAKQPPSQGLPKTICPLC--NTTELLLHVPEKA 605 Query: 877 TTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQ--QNLYHPGALTGTPPSLPPGPSAQS 934 T ++ Q+ + PHL + N AL G L P PS+ Sbjct: 606 NFNTCTECQTTVCSLCGFNPN----PHLTEVKEWLCLNCQMKRALGG---DLAPVPSSPQ 658 Query: 935 PQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPP 994 P+ A+ T+ A + ++ AP P P L+ P Sbjct: 659 PKLKTAPVTTTSAVSKSSPQPQQTSPK--KDAAPKQDLSKAPEPKKPPP------LVKQP 710 Query: 995 QSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQP 1032 HG P A +LS P P + Q + P Sbjct: 711 TLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAP 748 Score = 55.1 bits (131), Expect = 4e-07 Identities = 99/449 (22%), Positives = 159/449 (35%), Gaps = 78/449 (17%) Query: 373 RPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGE 432 +P L + P + SSP P + + P + KA P + + P+ S Sbjct: 658 QPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPS 717 Query: 433 TSVPPPPAVGRMYPPRSPKSAA------PAPISASCPEPPIGSAVPTSSASIPVTSSVSD 486 PP + P PK + AP++ P+ P V ++ + +S+ + Sbjct: 718 AKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQP--KMVKPTTDLVSSSSATTK 775 Query: 487 PGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELR 546 P + S S +K S K P ++ P E++ Sbjct: 776 PDIPSSKVQSQAEEKTTPPLKTDSAK-PSQSFPPTG--------------------EKVS 814 Query: 547 KFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDK 606 F ++ +P+S + P P E KG +K+VD + E P ++T+ +S K Sbjct: 815 PFDSKAIPRPASDSKIISHPGP----SSESKG-QKQVDPVQKKE---EPKKAQTK-MSPK 865 Query: 607 EDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN----PN 662 D P+ P G P PP P T V + K + EQ ++ +LN + Sbjct: 866 PDAKPM-PKG------SPTPPGPRPTAGQTVPTPQQSPKPQ----EQSRRFSLNLGSITD 914 Query: 663 AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722 A + PT P +V T G S S + TAGQ G +S P Sbjct: 915 APKSQPTTPQETV---TGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG-------APM 964 Query: 723 VQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPAS---------APPMMQAAAA 773 QAP P S P G+ A P + + PA+ AP + + Sbjct: 965 KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETE 1024 Query: 774 AGPPLV------AATPYSSYIPYNPQQFP 796 PP + A P + +P ++ P Sbjct: 1025 KKPPPIKDSKSLTAEPQKAVLPTKLEKSP 1053 Score = 51.2 bits (121), Expect = 5e-06 Identities = 42/119 (35%), Positives = 53/119 (44%), Gaps = 17/119 (14%) Query: 6 PLQQPSQPQQPPPTQQAVARRP----PGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61 P QQP + PPTQQ +P PG SP PGP T PGP + GP Sbjct: 401 PAQQPGPAK--PPTQQVGTPKPLAQQPGLQSPAKA--PGPTKTPVQQPGPGKIPAQQAGP 456 Query: 62 --VAAAGSGLRRGAEGILAPQPPPPQQ------HQERPGAAAIGSARGQSTGKGPPQSP 112 +A +G + + P PPPQQ ++PG+A S + ST K PPQ P Sbjct: 457 GKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGST-KPPPQQP 514 Score = 44.7 bits (104), Expect = 5e-04 Identities = 39/119 (32%), Positives = 45/119 (37%), Gaps = 30/119 (25%) Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPP--NGGLPGPLA----TSAAPPGPPAAASPCL 59 P+QQP+ P +PP Q + PG PP GL PLA T P PP P Sbjct: 305 PIQQPT-PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363 Query: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQ------HQERPGAAAIGSARGQSTGKGPPQSP 112 P L P PP QQ E+PG A+ G GK P Q P Sbjct: 364 QP---------------LGPAKPPAQQTGSEKPSSEQPGPKALAQPPG--VGKTPAQQP 405 Score = 39.3 bits (90), Expect = 0.020 Identities = 34/101 (33%), Positives = 41/101 (40%), Gaps = 16/101 (15%) Query: 3 KPQPLQQPSQPQQPPPTQQAVARRP---PGGTSPPNGGLPGPLATSAAPPGPPAAASPCL 59 KP P QQP P +PPP Q A+ P PG T PP PGP S PG + P Sbjct: 478 KPPP-QQPG-PAKPPPQQPGSAKPPSQQPGSTKPPPQQ-PGPAKPSPQQPG--STKPPSQ 532 Query: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSAR 100 P +A S + P P P Q + GS + Sbjct: 533 QPGSAKPSAQQ--------PSPAKPSAQQSTKPVSQTGSGK 565 Score = 37.7 bits (86), Expect = 0.059 Identities = 31/83 (37%), Positives = 38/83 (45%), Gaps = 8/83 (9%) Query: 6 PLQQPSQPQQPPPTQQAVAR---RPPGGTSPPNGGLPGPLATSAAPPGP-PAAASPCLGP 61 P QQP + PPP Q A+ + PG T PP+ PG SA P P +A P Sbjct: 500 PSQQPGSTK-PPPQQPGPAKPSPQQPGSTKPPS-QQPGSAKPSAQQPSPAKPSAQQSTKP 557 Query: 62 VAAAGSG--LRRGAEGILAPQPP 82 V+ GSG L+ A QPP Sbjct: 558 VSQTGSGKPLQPPTVSPSAKQPP 580 Score = 36.6 bits (83), Expect = 0.13 Identities = 36/112 (32%), Positives = 45/112 (40%), Gaps = 13/112 (11%) Query: 6 PLQQPSQ---PQQPPPTQQAVARRPP--GGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 P + PSQ P +PPP Q A+ PP G++ P PG PG PA SP Sbjct: 466 PTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPG-PAKPSP-QQ 523 Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112 P + + G+ A QP P +P A Q TG G P P Sbjct: 524 PGSTKPPSQQPGSAKPSAQQPSP-----AKPSAQQSTKPVSQ-TGSGKPLQP 569 Score = 35.4 bits (80), Expect = 0.29 Identities = 34/114 (29%), Positives = 46/114 (40%), Gaps = 12/114 (10%) Query: 4 PQPLQQPSQPQQPP--PTQQA----VARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASP 57 P P + P Q P P QQA + + G T PP+ LPGP PGP A P Sbjct: 434 PGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ-LPGPAKPPPQQPGP--AKPP 490 Query: 58 CLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111 P +A + G+ QP P + ++PG+ S Q G P + Sbjct: 491 PQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS---QQPGSAKPSA 541 Score = 35.4 bits (80), Expect = 0.29 Identities = 61/265 (23%), Positives = 101/265 (38%), Gaps = 51/265 (19%) Query: 390 SSPGPGSEARGINGGPSRMSP--KAQRPLRGAKTLS-SPSNRPSGETSVPPP---PAVGR 443 S PGP SE++G ++ P K + P + +S P +P + S PP P G+ Sbjct: 832 SHPGPSSESKG----QKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQ 887 Query: 444 MYPP--RSPK-------------SAAPAPISA-SCPEPPIGSAVPTSSASI-----PVTS 482 P +SPK S AP S + P+ + + ASI + S Sbjct: 888 TVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947 Query: 483 SVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQL 542 + PG S S + AP + +++ P ++ G+ P K + Sbjct: 948 TAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKS---------TGQAPPAP--AKSIPV 996 Query: 543 EELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGL--LTSEPMGSPVSSKT 600 ++ K A KL+P + P + + E + K + LT+EP + + +K Sbjct: 997 KKETKAPAAEKLEPKAEQA-------PTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKL 1049 Query: 601 ESVSDKEDKPPLAPSGGTEGPEQPP 625 E E PL + G + PP Sbjct: 1050 EKSPKPESTCPLCKTELNIGSKDPP 1074 Score = 34.7 bits (78), Expect = 0.50 Identities = 37/128 (28%), Positives = 47/128 (36%), Gaps = 28/128 (21%) Query: 3 KPQPLQQPSQP--------QQP----PPTQQAVARRPP----GGTSPPNGGLPGPLATSA 46 +P P + P+QP QQP PP Q +PP G PP G S+ Sbjct: 325 QPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP-AQQTGSEKPSS 383 Query: 47 APPGPPAAAS-PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTG 105 PGP A A P +G A G P PP QQ A + + Sbjct: 384 EQPGPKALAQPPGVGKTPAQQPG----------PAKPPTQQVGTPKPLAQQPGLQSPAKA 433 Query: 106 KGPPQSPV 113 GP ++PV Sbjct: 434 PGPTKTPV 441 Score = 31.2 bits (69), Expect = 5.5 Identities = 36/138 (26%), Positives = 48/138 (34%), Gaps = 15/138 (10%) Query: 575 EPKGKEKEVDGLLTSEPMGSPV---------SSKTESVSDKEDKPPLAPSGGTEGPEQPP 625 E G+EK L + P S + SS + + PP P P PP Sbjct: 2365 ETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPP 2424 Query: 626 PPCPSQTGSPPVGLIKGEDKDEGPVAEQV----KKSTLNPNAKEFNPTKPLLSVNKSTST 681 PP P T P L K + PV +TL A + P+ + T+ Sbjct: 2425 PPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRI--CTTA 2482 Query: 682 PTSPGPRTHSTPSIPVLT 699 P P+ S PS V T Sbjct: 2483 PPPVPPKPSSIPSGLVFT 2500 Score = 30.4 bits (67), Expect = 9.4 Identities = 28/122 (22%), Positives = 53/122 (43%), Gaps = 11/122 (9%) Query: 533 LQNEQKRFQLEELRKFGAQFKLQP---SSSPENSLDPFPPRILKEEPKGKEKEVDGLLTS 589 +++E+K+ LEE + KL P +S+PE +LK + + E++++G + Sbjct: 1227 IRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHD----LLKSQVQIAEEKLEGRVAP 1282 Query: 590 EPMGSPVSSKTESVSDKEDKPPLAPSGGTEGP----EQPPPPCPSQTGSPPVGLIKGEDK 645 + + +T+ P P + EQP PPC ++ G K E + Sbjct: 1283 KTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKE 1342 Query: 646 DE 647 D+ Sbjct: 1343 DD 1344 Score = 30.4 bits (67), Expect = 9.4 Identities = 38/155 (24%), Positives = 57/155 (36%), Gaps = 18/155 (11%) Query: 534 QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593 + E K+ + R G SS E L +LKE+ K +E E Sbjct: 1749 KGESKQQRKARHRPHGPLLPTIEDSSEEEELRE-EEELLKEQEKQREIEQQ--------- 1798 Query: 594 SPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP-CPSQTGSPPVGLIKGEDKDE---GP 649 K+ S K+DK L E P+ PP P + SP L + + +E Sbjct: 1799 ---QRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSS 1855 Query: 650 VAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTS 684 +E +P E +P K ++ V K PT+ Sbjct: 1856 CSEYSPSIESDPEGFEISPEK-IIEVQKVYKLPTA 1889 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 79.7 bits (195), Expect = 1e-14 Identities = 162/676 (23%), Positives = 235/676 (34%), Gaps = 158/676 (23%) Query: 375 GLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETS 434 GL++ G SP + G+ S++S + +R + A +S P G S Sbjct: 15 GLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQI--AAVMSRAQGLPKG--S 70 Query: 435 VPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISP 494 VPP A SP + +S P P S P DPG P Sbjct: 71 VPPAAA-------ESPSMHRKQELDSSHP--------PKQSGRPP------DPG----RP 105 Query: 495 ASPKISLA-PTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKF----G 549 A P +S + TD K PGR+ P ++ L+ + R L+E K G Sbjct: 106 AQPGLSKSRTTDTFRSEQKLPGRS--PSTIS--------LKESKSRTDLKEEHKSSMMPG 155 Query: 550 AQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKED- 608 ++ S+ + ++ F P L + + ++E ++K + V KE Sbjct: 156 FLSEVNALSAVSSVVNKFNPFDLISDSEASQEE--------------TTKKQKVVQKEQG 201 Query: 609 ------KPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPN 662 KPPL +QPP P P Q G G D P+ + +++ Sbjct: 202 KPEGIIKPPLQ--------QQPPKPIPKQQG-------PGRD----PLQQDGTPKSISSQ 242 Query: 663 AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722 E ++P K PT H+ +P+ Q + PQ Sbjct: 243 QPEKIKSQP-PGTGKPIQGPTQTPQTDHA--KLPL-----------QRDASRPQTKQADI 288 Query: 723 VQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAAT 782 V+ + P S S P Q G + P ++ QP A P Q + P +A Sbjct: 289 VRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGH-EKSQPGPAKPPAQPSGLTKP--LAQQ 345 Query: 783 PYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQY 842 P + P P PG ++P P+ + P +GS + Sbjct: 346 PGTVKPPVQP---PG-----------TTKPPAQPLGPAKPPAQQTGS-----------EK 380 Query: 843 PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAG-QA 901 PS+EQP P+AL + P + A QP PA PT Q P P+ Q G Q+ Sbjct: 381 PSSEQPGPKAL------AQPPGVGKTPAQQPGPAKPPT-----QQVGTPKPLAQQPGLQS 429 Query: 902 PHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMA 961 P G + + PG G P+ GP S Q + P QLP Sbjct: 430 PAKAPGPTKTPVQQPG--PGKIPAQQAGPGKTSAQQTGPTKPP------SQLP------G 475 Query: 962 HVTQAHVQTGITAAPPPHPGAPHPP--QVMLLHPPQSHGGPPQGAVPQSGVPALSASTPS 1019 Q G PP PG+ PP Q PP GP + + Q G S PS Sbjct: 476 PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPG----STKPPS 531 Query: 1020 PYPYIGHPQGEQPGQA 1035 P P +QP A Sbjct: 532 QQPGSAKPSAQQPSPA 547 Score = 68.9 bits (167), Expect = 2e-11 Identities = 157/690 (22%), Positives = 231/690 (33%), Gaps = 123/690 (17%) Query: 333 QGSGRESPSLASREGKYIPLPQRVREGPR---GGVRCSSSRGG-------RPGLSSLPPR 382 Q +G E PS K + P V + P G + + + G +PGL S P + Sbjct: 374 QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQS-PAK 432 Query: 383 --GPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGET--SVPPP 438 GP PGPG + GP + S + P + L P+ P + + PPP Sbjct: 433 APGPTKTPVQQPGPG-KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPP 491 Query: 439 PAVGRMYPP-----------RSPKSAAPAPISASCPEPPI---GSAVPTSSASIPV---- 480 G PP + P A P+P +PP GSA P++ P Sbjct: 492 QQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSA 551 Query: 481 ---TSSVSDPGVG------SISPAS--------PK--ISLAPTDVKELSTKEPGRTLEPQ 521 T VS G G ++SP++ PK L T L E Sbjct: 552 QQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCT 611 Query: 522 ELARIAGKVPGLQNEQKRFQLEELRKFGAQFK------LQP-SSSPENSLDPFP----PR 570 E + G +++E Q K L P SSP+ L P Sbjct: 612 ECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSA 671 Query: 571 ILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEG-----PEQPP 625 + K P+ ++ TS + + + PPL G +QPP Sbjct: 672 VSKSSPQPQQ-------TSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724 Query: 626 PPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSP 685 +PP ++D+ PVA+ K K PT L+S + +T+ P P Sbjct: 725 EADSLSKPAPPKEPSVPSEQDKAPVADDKPK-----QPKMVKPTTDLVSSSSATTKPDIP 779 Query: 686 GPRTHS------TPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPG 739 + S TP + +A S + P P A+ P +S+ PG Sbjct: 780 SSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSP--FDSKAIPRPASDSKIISH--PG 835 Query: 740 QQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQP 799 + +G K P Q+ + +P A M A P P S P P+ GQ Sbjct: 836 PSSESKGQKQVDPVQKKE--EPKKAQTKMSPKPDAKP-----MPKGSPTPPGPRPTAGQT 888 Query: 800 AMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQ 859 + P + QS L GS ++ + P+ Q T Sbjct: 889 VPTPQQSPKPQE-------QSRRFSLNLGS-----ITDAPKSQPTTPQETVTGKLFGFGA 936 Query: 860 SYPHHATQL--HAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPG 917 S A+ L A QP P + P Q AP+P Q Q P +GQ Sbjct: 937 SIFSQASNLISTAGQPGPHSQSGPGAPMKQ--APAPSQPPTSQGPPKSTGQ--------- 985 Query: 918 ALTGTPPSLPPGPSAQSPQSSFPQPAAVYA 947 A S+P ++P + +P A A Sbjct: 986 APPAPAKSIPVKKETKAPAAEKLEPKAEQA 1015 Score = 57.4 bits (137), Expect = 7e-08 Identities = 142/638 (22%), Positives = 197/638 (30%), Gaps = 114/638 (17%) Query: 405 PSRMSPKAQRPLRG-----AKTLSSPSNRPSGETSVPP---PPAVGRMYPPRSPKSAAPA 456 P + PK Q P R S S +P S PP P G P++ + P Sbjct: 215 PPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPL 274 Query: 457 PISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGR 516 AS P+ V S P S S P + +P P + + +P Sbjct: 275 QRDASRPQTKQADIVRGESVK-PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP-- 331 Query: 517 TLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEP 576 +P L + + PG + Q K AQ L P+ P P + P Sbjct: 332 PAQPSGLTKPLAQQPG--TVKPPVQPPGTTKPPAQ-PLGPAKPPAQQTGSEKPSSEQPGP 388 Query: 577 KGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPP 636 K + T P T+ V + PLA G + P + P P + P Sbjct: 389 KALAQPPGVGKTPAQQPGPAKPPTQQVGTPK---PLAQQPGLQSPAKAPGPTKTPVQQPG 445 Query: 637 VGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIP 696 G I + G +A++ PTKP + PGP Sbjct: 446 PGKIPAQQAGPG-----------KTSAQQTGPTKPPSQL---------PGP--------- 476 Query: 697 VLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRS 756 + P GPA PQ P S P QQ GS P Sbjct: 477 ---------------AKPPPQQPGPAKPPPQQ---PGSAKPPSQQ------PGSTKP--- 509 Query: 757 DQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAP 816 QP A P Q + PP QP +P A PS + Sbjct: 510 PPQQPGPAKPSPQQPGSTKPP------------------SQQPGSAKPSAQQPSPAKPSA 551 Query: 817 MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPA 876 + P T P + S PSA+QP Q L T+ + T+L H P+ A Sbjct: 552 QQSTKPVSQTGSGKPLQPPTVS----PSAKQPPSQGLPKTICPLC--NTTELLLHVPEKA 605 Query: 877 TTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQ--QNLYHPGALTGTPPSLPPGPSAQS 934 T ++ Q+ + PHL + N AL G L P PS+ Sbjct: 606 NFNTCTECQTTVCSLCGFNPN----PHLTEVKEWLCLNCQMKRALGG---DLAPVPSSPQ 658 Query: 935 PQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPP 994 P+ A+ T+ A + ++ AP P P L+ P Sbjct: 659 PKLKTAPVTTTSAVSKSSPQPQQTSPK--KDAAPKQDLSKAPEPKKPPP------LVKQP 710 Query: 995 QSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQP 1032 HG P A +LS P P + Q + P Sbjct: 711 TLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAP 748 Score = 55.1 bits (131), Expect = 4e-07 Identities = 99/449 (22%), Positives = 159/449 (35%), Gaps = 78/449 (17%) Query: 373 RPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGE 432 +P L + P + SSP P + + P + KA P + + P+ S Sbjct: 658 QPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPS 717 Query: 433 TSVPPPPAVGRMYPPRSPKSAA------PAPISASCPEPPIGSAVPTSSASIPVTSSVSD 486 PP + P PK + AP++ P+ P V ++ + +S+ + Sbjct: 718 AKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQP--KMVKPTTDLVSSSSATTK 775 Query: 487 PGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELR 546 P + S S +K S K P ++ P E++ Sbjct: 776 PDIPSSKVQSQAEEKTTPPLKTDSAK-PSQSFPPTG--------------------EKVS 814 Query: 547 KFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDK 606 F ++ +P+S + P P E KG +K+VD + E P ++T+ +S K Sbjct: 815 PFDSKAIPRPASDSKIISHPGP----SSESKG-QKQVDPVQKKE---EPKKAQTK-MSPK 865 Query: 607 EDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN----PN 662 D P+ P G P PP P T V + K + EQ ++ +LN + Sbjct: 866 PDAKPM-PKG------SPTPPGPRPTAGQTVPTPQQSPKPQ----EQSRRFSLNLGSITD 914 Query: 663 AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722 A + PT P +V T G S S + TAGQ G +S P Sbjct: 915 APKSQPTTPQETV---TGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG-------APM 964 Query: 723 VQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPAS---------APPMMQAAAA 773 QAP P S P G+ A P + + PA+ AP + + Sbjct: 965 KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETE 1024 Query: 774 AGPPLV------AATPYSSYIPYNPQQFP 796 PP + A P + +P ++ P Sbjct: 1025 KKPPPIKDSKSLTAEPQKAVLPTKLEKSP 1053 Score = 51.2 bits (121), Expect = 5e-06 Identities = 42/119 (35%), Positives = 53/119 (44%), Gaps = 17/119 (14%) Query: 6 PLQQPSQPQQPPPTQQAVARRP----PGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61 P QQP + PPTQQ +P PG SP PGP T PGP + GP Sbjct: 401 PAQQPGPAK--PPTQQVGTPKPLAQQPGLQSPAKA--PGPTKTPVQQPGPGKIPAQQAGP 456 Query: 62 --VAAAGSGLRRGAEGILAPQPPPPQQ------HQERPGAAAIGSARGQSTGKGPPQSP 112 +A +G + + P PPPQQ ++PG+A S + ST K PPQ P Sbjct: 457 GKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGST-KPPPQQP 514 Score = 44.7 bits (104), Expect = 5e-04 Identities = 39/119 (32%), Positives = 45/119 (37%), Gaps = 30/119 (25%) Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPP--NGGLPGPLA----TSAAPPGPPAAASPCL 59 P+QQP+ P +PP Q + PG PP GL PLA T P PP P Sbjct: 305 PIQQPT-PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363 Query: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQ------HQERPGAAAIGSARGQSTGKGPPQSP 112 P L P PP QQ E+PG A+ G GK P Q P Sbjct: 364 QP---------------LGPAKPPAQQTGSEKPSSEQPGPKALAQPPG--VGKTPAQQP 405 Score = 39.3 bits (90), Expect = 0.020 Identities = 34/101 (33%), Positives = 41/101 (40%), Gaps = 16/101 (15%) Query: 3 KPQPLQQPSQPQQPPPTQQAVARRP---PGGTSPPNGGLPGPLATSAAPPGPPAAASPCL 59 KP P QQP P +PPP Q A+ P PG T PP PGP S PG + P Sbjct: 478 KPPP-QQPG-PAKPPPQQPGSAKPPSQQPGSTKPPPQQ-PGPAKPSPQQPG--STKPPSQ 532 Query: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSAR 100 P +A S + P P P Q + GS + Sbjct: 533 QPGSAKPSAQQ--------PSPAKPSAQQSTKPVSQTGSGK 565 Score = 37.7 bits (86), Expect = 0.059 Identities = 31/83 (37%), Positives = 38/83 (45%), Gaps = 8/83 (9%) Query: 6 PLQQPSQPQQPPPTQQAVAR---RPPGGTSPPNGGLPGPLATSAAPPGP-PAAASPCLGP 61 P QQP + PPP Q A+ + PG T PP+ PG SA P P +A P Sbjct: 500 PSQQPGSTK-PPPQQPGPAKPSPQQPGSTKPPS-QQPGSAKPSAQQPSPAKPSAQQSTKP 557 Query: 62 VAAAGSG--LRRGAEGILAPQPP 82 V+ GSG L+ A QPP Sbjct: 558 VSQTGSGKPLQPPTVSPSAKQPP 580 Score = 36.6 bits (83), Expect = 0.13 Identities = 36/112 (32%), Positives = 45/112 (40%), Gaps = 13/112 (11%) Query: 6 PLQQPSQ---PQQPPPTQQAVARRPP--GGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 P + PSQ P +PPP Q A+ PP G++ P PG PG PA SP Sbjct: 466 PTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPG-PAKPSP-QQ 523 Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112 P + + G+ A QP P +P A Q TG G P P Sbjct: 524 PGSTKPPSQQPGSAKPSAQQPSP-----AKPSAQQSTKPVSQ-TGSGKPLQP 569 Score = 35.4 bits (80), Expect = 0.29 Identities = 34/114 (29%), Positives = 46/114 (40%), Gaps = 12/114 (10%) Query: 4 PQPLQQPSQPQQPP--PTQQA----VARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASP 57 P P + P Q P P QQA + + G T PP+ LPGP PGP A P Sbjct: 434 PGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ-LPGPAKPPPQQPGP--AKPP 490 Query: 58 CLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111 P +A + G+ QP P + ++PG+ S Q G P + Sbjct: 491 PQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS---QQPGSAKPSA 541 Score = 35.4 bits (80), Expect = 0.29 Identities = 61/265 (23%), Positives = 101/265 (38%), Gaps = 51/265 (19%) Query: 390 SSPGPGSEARGINGGPSRMSP--KAQRPLRGAKTLS-SPSNRPSGETSVPPP---PAVGR 443 S PGP SE++G ++ P K + P + +S P +P + S PP P G+ Sbjct: 832 SHPGPSSESKG----QKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQ 887 Query: 444 MYPP--RSPK-------------SAAPAPISA-SCPEPPIGSAVPTSSASI-----PVTS 482 P +SPK S AP S + P+ + + ASI + S Sbjct: 888 TVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947 Query: 483 SVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQL 542 + PG S S + AP + +++ P ++ G+ P K + Sbjct: 948 TAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKS---------TGQAPPAP--AKSIPV 996 Query: 543 EELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGL--LTSEPMGSPVSSKT 600 ++ K A KL+P + P + + E + K + LT+EP + + +K Sbjct: 997 KKETKAPAAEKLEPKAEQA-------PTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKL 1049 Query: 601 ESVSDKEDKPPLAPSGGTEGPEQPP 625 E E PL + G + PP Sbjct: 1050 EKSPKPESTCPLCKTELNIGSKDPP 1074 Score = 34.7 bits (78), Expect = 0.50 Identities = 37/128 (28%), Positives = 47/128 (36%), Gaps = 28/128 (21%) Query: 3 KPQPLQQPSQP--------QQP----PPTQQAVARRPP----GGTSPPNGGLPGPLATSA 46 +P P + P+QP QQP PP Q +PP G PP G S+ Sbjct: 325 QPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP-AQQTGSEKPSS 383 Query: 47 APPGPPAAAS-PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTG 105 PGP A A P +G A G P PP QQ A + + Sbjct: 384 EQPGPKALAQPPGVGKTPAQQPG----------PAKPPTQQVGTPKPLAQQPGLQSPAKA 433 Query: 106 KGPPQSPV 113 GP ++PV Sbjct: 434 PGPTKTPV 441 Score = 31.2 bits (69), Expect = 5.5 Identities = 36/138 (26%), Positives = 48/138 (34%), Gaps = 15/138 (10%) Query: 575 EPKGKEKEVDGLLTSEPMGSPV---------SSKTESVSDKEDKPPLAPSGGTEGPEQPP 625 E G+EK L + P S + SS + + PP P P PP Sbjct: 2365 ETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPP 2424 Query: 626 PPCPSQTGSPPVGLIKGEDKDEGPVAEQV----KKSTLNPNAKEFNPTKPLLSVNKSTST 681 PP P T P L K + PV +TL A + P+ + T+ Sbjct: 2425 PPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRI--CTTA 2482 Query: 682 PTSPGPRTHSTPSIPVLT 699 P P+ S PS V T Sbjct: 2483 PPPVPPKPSSIPSGLVFT 2500 Score = 30.4 bits (67), Expect = 9.4 Identities = 28/122 (22%), Positives = 53/122 (43%), Gaps = 11/122 (9%) Query: 533 LQNEQKRFQLEELRKFGAQFKLQP---SSSPENSLDPFPPRILKEEPKGKEKEVDGLLTS 589 +++E+K+ LEE + KL P +S+PE +LK + + E++++G + Sbjct: 1227 IRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHD----LLKSQVQIAEEKLEGRVAP 1282 Query: 590 EPMGSPVSSKTESVSDKEDKPPLAPSGGTEGP----EQPPPPCPSQTGSPPVGLIKGEDK 645 + + +T+ P P + EQP PPC ++ G K E + Sbjct: 1283 KTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKE 1342 Query: 646 DE 647 D+ Sbjct: 1343 DD 1344 Score = 30.4 bits (67), Expect = 9.4 Identities = 38/155 (24%), Positives = 57/155 (36%), Gaps = 18/155 (11%) Query: 534 QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593 + E K+ + R G SS E L +LKE+ K +E E Sbjct: 1749 KGESKQQRKARHRPHGPLLPTIEDSSEEEELRE-EEELLKEQEKQREIEQQ--------- 1798 Query: 594 SPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP-CPSQTGSPPVGLIKGEDKDE---GP 649 K+ S K+DK L E P+ PP P + SP L + + +E Sbjct: 1799 ---QRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSS 1855 Query: 650 VAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTS 684 +E +P E +P K ++ V K PT+ Sbjct: 1856 CSEYSPSIESDPEGFEISPEK-IIEVQKVYKLPTA 1889 >gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] Length = 416 Score = 79.3 bits (194), Expect = 2e-14 Identities = 113/436 (25%), Positives = 142/436 (32%), Gaps = 58/436 (13%) Query: 580 EKEVDGLLTSEPMGSPVS--SKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPV 637 ++E L+ P G+P +K + KP P G P+ PPPP G PP Sbjct: 25 QEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP- 83 Query: 638 GLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPV 697 +G +K +GP + K +P P P P P+ + P P Sbjct: 84 ---QGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP-------PGKPQGPPPQGGNQPQGPP 133 Query: 698 LTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSD 757 G+ PQ + PQ GP P P ++ G PPQ + Sbjct: 134 PPPGKPQGPPPQGGNK-PQ---GPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGN 189 Query: 758 QHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPM 817 Q Q PP GPP P P P PG+P P SQ +P Sbjct: 190 QPQGPPPPP----GKPQGPP-----PQGGNKPQGPPP-PGKPQGPPPQGDNKSQSARSP- 238 Query: 818 LQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPAT 877 P+ G PQ + PQ P PQ P P P Sbjct: 239 -PGKPQ----GPPPQG---GNQPQGPPPPPGKPQG---------PPPQGGNKPQGPPPPG 281 Query: 878 TPTGSQPQS---QHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPP---SLPPGPS 931 P G PQ ++ SP G P G QPQ PG G PP + P GP Sbjct: 282 KPQGPPPQGGSKSRSSRSPPGKPQGPPPQ-GGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 340 Query: 932 AQS-PQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVML 990 PQ P P + P G + + G PPP G P PQ Sbjct: 341 PPGKPQG--PPPQGGSKSRSARSPPGKPQGPPQQEGNNPQG---PPPPAGGNPQQPQAPP 395 Query: 991 LHPPQSHGGPPQGAVP 1006 PQ PPQG P Sbjct: 396 AGQPQGPPRPPQGGRP 411 Score = 73.6 bits (179), Expect = 1e-12 Identities = 102/393 (25%), Positives = 128/393 (32%), Gaps = 67/393 (17%) Query: 555 QPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSS-KTESVSDKEDKPPLA 613 QP P P P + P+G K +P G P K+ S KP Sbjct: 67 QPQGPP-----PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGP 121 Query: 614 PSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLL 673 P G P+ PPPP G PP +G +K +GP P K P P Sbjct: 122 PPQGGNQPQGPPPPPGKPQGPPP----QGGNKPQGP----------PPPGKPQGP--PPQ 165 Query: 674 SVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQA---PQMYP 730 NKS S+ + PG P G PQ P GP Q PQ P Sbjct: 166 GDNKSRSSRSPPGKPQGPPP---------QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 216 Query: 731 YPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPY 790 P GK +G PPQ ++ Q A +PP GPP P P Sbjct: 217 PP---------GKPQGP----PPQGDNKSQSARSPP----GKPQGPP-----PQGGNQPQ 254 Query: 791 NPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTP 850 P PG+P P Q P P+ G PQ S + + P + P Sbjct: 255 GPPPPPGKPQGPPPQGGNKPQ---GPPPPGKPQ----GPPPQGGSKSRSSRSPPGKPQGP 307 Query: 851 QALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQ 910 Q P + PQ P G P + P P ++ G+PQ Sbjct: 308 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQ 367 Query: 911 QNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPA 943 P G P PP P+ +PQ PA Sbjct: 368 ----GPPQQEGNNPQGPPPPAGGNPQQPQAPPA 396 Score = 68.9 bits (167), Expect = 2e-11 Identities = 114/428 (26%), Positives = 133/428 (31%), Gaps = 62/428 (14%) Query: 650 VAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQ--SGLYS 707 VA S N N P L P G + PS P G G Sbjct: 8 VALLALSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQ 67 Query: 708 PQYISYIPQIHMGPAVQA---PQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASA 764 PQ P GP Q PQ P P GK +G PPQ P S Sbjct: 68 PQGPPPPPGKPQGPPPQGGNKPQGPPPP---------GKPQGP----PPQGDKSRSPRSP 114 Query: 765 PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRM 824 P Q GPP P P P PG+P P Q P P+ Sbjct: 115 PGKPQ-----GPP-----PQGGNQPQGPPPPPGKPQGPPPQGGNKPQ---GPPPPGKPQ- 160 Query: 825 LTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQP 884 G PQ S + + P + P Q P + PQ P G P Sbjct: 161 ---GPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 217 Query: 885 QSQHAAPSPVQHQAGQA-----------PHLGSGQPQQNLYHPGALTGTPP---SLPPGP 930 + P P Q+ P G QPQ PG G PP + P GP Sbjct: 218 PGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP 277 Query: 931 SAQS-PQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVM 989 PQ P P + P G + G PPP PG P P Sbjct: 278 PPPGKPQG--PPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQG----PPPPPGKPQGPPPQ 331 Query: 990 LLHPPQSHGGP--PQGAVPQSGVPALSASTPSPYPYIGHPQ--GEQPGQAPGFPGGADDR 1045 + PQ P PQG PQ G + SA +P P G PQ G P Q P P G + + Sbjct: 332 GGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQ-GPPQQEGNNP-QGPPPPAGGNPQ 389 Query: 1046 IREFSLAG 1053 + AG Sbjct: 390 QPQAPPAG 397 Score = 64.7 bits (156), Expect = 4e-10 Identities = 109/435 (25%), Positives = 140/435 (32%), Gaps = 57/435 (13%) Query: 335 SGRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGP 394 S ESPSL + + P PQ + P+G G P P+GP GP Sbjct: 24 SQEESPSLIAGNPQGAP-PQGGNK-PQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 81 Query: 395 GSEARGINGGPSRMSPKAQRPLRGAKTLS--SPSNRPSGET--------SVPPPPAVGRM 444 + GP P +G K+ S SP +P G PPPP + Sbjct: 82 PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 141 Query: 445 YPPRSP-KSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAP 503 PP+ K P P PP G SS S P P G+ P P Sbjct: 142 PPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKP 201 Query: 504 TDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFG--AQFKLQPSSSPE 561 +P P + G P N+ + + + G Q QP P Sbjct: 202 QGPPPQGGNKP---QGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPP- 257 Query: 562 NSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPV--SSKTESVSDKEDKPPLAPSGGTE 619 P P + P+G K +P G P SK+ S KP P G Sbjct: 258 ----PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGN 313 Query: 620 GPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKST 679 P+ PPPP G PP +G +K +GP P KP Sbjct: 314 QPQGPPPPPGKPQGPPP----QGGNKPQGPPP----------------PGKP-------Q 346 Query: 680 STPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPG 739 P G ++ S S P G PQ PQ PA PQ P + G Sbjct: 347 GPPPQGGSKSRSARSPPGKPQG-----PPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQG 401 Query: 740 QQGKYRGAKGSLPPQ 754 +G + S PPQ Sbjct: 402 PPRPPQGGRPSRPPQ 416 Score = 61.2 bits (147), Expect = 5e-09 Identities = 104/431 (24%), Positives = 134/431 (31%), Gaps = 57/431 (13%) Query: 394 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSA 453 P A G P + K Q P P + + PPPP PP + Sbjct: 29 PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 88 Query: 454 APAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKE 513 P P+ P + S P P G P P P K Sbjct: 89 PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP----PPPPGKPQGPPP 144 Query: 514 PG--RTLEPQELARIAGKVPGLQNEQKRFQLEELRKFG--AQFKLQPSSSPENSLDPFPP 569 G + P + G P N+ + + + G Q QP P P P Sbjct: 145 QGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPP-----PPPG 199 Query: 570 RILKEEPKGKEKEVDGLLTSEPMGSPV--SSKTESVSDKEDKPPLAPSGGTEGPEQPPPP 627 + P+G K +P G P +K++S KP P G P+ PPPP Sbjct: 200 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPP 259 Query: 628 CPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGP 687 G PP +G +K +GP P K P P +KS S+ + PG Sbjct: 260 PGKPQGPPP----QGGNKPQGP----------PPPGKPQGP--PPQGGSKSRSSRSPPGK 303 Query: 688 RTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQA---PQMYPYPVSNSVPGQQGKY 744 P G PQ P GP Q PQ P P P QG Sbjct: 304 PQGPPP---------QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGS 354 Query: 745 RGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFP-GQP--AM 801 + PP + PP + GPP P + P PQ P GQP Sbjct: 355 KSRSARSPPGK------PQGPPQQEGNNPQGPP-----PPAGGNPQQPQAPPAGQPQGPP 403 Query: 802 MQPMAHYPSQP 812 P PS+P Sbjct: 404 RPPQGGRPSRP 414 Score = 48.9 bits (115), Expect = 3e-05 Identities = 42/131 (32%), Positives = 49/131 (37%), Gaps = 25/131 (19%) Query: 3 KPQPLQQPSQPQQPPP---TQQAVARRPPG--------GTSPPNGGLPGPLATSAAPP-- 49 KPQ P +PQ PPP + AR PPG G + P G P P PP Sbjct: 211 KPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 270 Query: 50 -----GPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQE------RPGAAAIGS 98 GPP P GP GS R PQ PPPQ + PG Sbjct: 271 GNKPQGPPPPGKP-QGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 329 Query: 99 ARGQSTGKGPP 109 +G + +GPP Sbjct: 330 PQGGNKPQGPP 340 Score = 48.5 bits (114), Expect = 3e-05 Identities = 42/131 (32%), Positives = 50/131 (38%), Gaps = 22/131 (16%) Query: 3 KPQPLQQPSQPQQPPP---TQQAVARRPPG--------GTSPPNGGLPGPLATSAAPP-- 49 KPQ P +PQ PPP ++ +R PPG G + P G P P PP Sbjct: 273 KPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 332 Query: 50 -----GPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQ---HQERPGAAAIGSARG 101 GPP P GP GS R PQ PP Q+ Q P A + Sbjct: 333 GNKPQGPPPPGKP-QGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQP 391 Query: 102 QSTGKGPPQSP 112 Q+ G PQ P Sbjct: 392 QAPPAGQPQGP 402 Score = 47.8 bits (112), Expect = 6e-05 Identities = 40/133 (30%), Positives = 51/133 (38%), Gaps = 19/133 (14%) Query: 3 KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLP-----GP-------LATSAAP 48 KPQ P Q +QPQ PPP PP G + P G P GP ++ +P Sbjct: 179 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSP 238 Query: 49 PG-----PPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQS 103 PG PP + GP G +G PQ PPP + P +R Sbjct: 239 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSR 298 Query: 104 TGKGPPQSPVFEG 116 + G PQ P +G Sbjct: 299 SPPGKPQGPPPQG 311 Score = 47.4 bits (111), Expect = 7e-05 Identities = 40/133 (30%), Positives = 51/133 (38%), Gaps = 19/133 (14%) Query: 3 KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLP-----GP-------LATSAAP 48 KPQ P Q +QPQ PPP PP G + P G P GP +S +P Sbjct: 117 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSP 176 Query: 49 PG-----PPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQS 103 PG PP + GP G +G PQ PPP + P ++ Sbjct: 177 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSAR 236 Query: 104 TGKGPPQSPVFEG 116 + G PQ P +G Sbjct: 237 SPPGKPQGPPPQG 249 Score = 45.4 bits (106), Expect = 3e-04 Identities = 45/131 (34%), Positives = 54/131 (41%), Gaps = 23/131 (17%) Query: 3 KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLP-----GP-------LATSAAP 48 KPQ P Q +QPQ PPP PP G + P G P GP +S +P Sbjct: 241 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP 300 Query: 49 PG-----PPAAASPCLGPVAAAGSGLRRGAEGILAPQ-PPPPQQHQERP--GAAAIGSAR 100 PG PP + GP G +G PQ PPPP + Q P G + SAR Sbjct: 301 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSAR 360 Query: 101 G-QSTGKGPPQ 110 +GPPQ Sbjct: 361 SPPGKPQGPPQ 371 Score = 45.1 bits (105), Expect = 4e-04 Identities = 35/109 (32%), Positives = 42/109 (38%), Gaps = 12/109 (11%) Query: 3 KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 KPQ P Q +QPQ PPP PP G + P G P P GPP Sbjct: 56 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP-----PGKPQGPPPQGDKSRS 110 Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109 P + G +G PQ PPP PG +G + +GPP Sbjct: 111 PRSPPGKPQGPPPQGGNQPQGPPPP-----PGKPQGPPPQGGNKPQGPP 154 Score = 44.3 bits (103), Expect = 6e-04 Identities = 37/117 (31%), Positives = 47/117 (40%), Gaps = 16/117 (13%) Query: 3 KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPG-----PPAAA 55 KPQ P Q ++PQ PPP +P G PP GG +S +PPG PP Sbjct: 262 KPQGPPPQGGNKPQGPPP-----PGKPQG--PPPQGG--SKSRSSRSPPGKPQGPPPQGG 312 Query: 56 SPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112 + GP G +G PQ PPP + P +R + G PQ P Sbjct: 313 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGP 369 Score = 43.1 bits (100), Expect = 0.001 Identities = 39/130 (30%), Positives = 47/130 (36%), Gaps = 24/130 (18%) Query: 3 KPQPLQQPSQPQQPPPT--QQAVARRPPG--------GTSPPNGGLPGPLATSAAPP--- 49 KPQ P +PQ PPP + R PPG G + P G P P PP Sbjct: 88 KPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 147 Query: 50 ----GPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQE------RPGAAAIGSA 99 GPP P GP + R PQ PPPQ + PG Sbjct: 148 NKPQGPPPPGKP-QGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 206 Query: 100 RGQSTGKGPP 109 +G + +GPP Sbjct: 207 QGGNKPQGPP 216 Score = 37.0 bits (84), Expect = 0.10 Identities = 32/105 (30%), Positives = 39/105 (37%), Gaps = 9/105 (8%) Query: 13 PQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRG 72 PQ PP + PP P G P P + P GPP GP G +G Sbjct: 36 PQGAPPQGGNKPQGPPSPPGKPQG--PPPQGGN-QPQGPPPPPGKPQGP-PPQGGNKPQG 91 Query: 73 AEGILAPQPPPPQQHQER-----PGAAAIGSARGQSTGKGPPQSP 112 PQ PPPQ + R PG +G + +GPP P Sbjct: 92 PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP 136 Score = 31.6 bits (70), Expect = 4.2 Identities = 21/61 (34%), Positives = 24/61 (39%), Gaps = 12/61 (19%) Query: 3 KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 KPQ P Q+ + PQ PP PP G +P P P PP PP P Sbjct: 365 KPQGPPQQEGNNPQGPP---------PPAGGNPQQPQAP-PAGQPQGPPRPPQGGRPSRP 414 Query: 61 P 61 P Sbjct: 415 P 415 >gi|55750053 atrophin-1 [Homo sapiens] Length = 1190 Score = 77.0 bits (188), Expect = 9e-14 Identities = 138/590 (23%), Positives = 198/590 (33%), Gaps = 101/590 (17%) Query: 490 GSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEEL---R 546 G SP +S + +D K +++ + +E + G E + EE + Sbjct: 31 GRASPGG--VSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPK 88 Query: 547 KFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD--GLLTSEPMGSPVSSKTESVS 604 K + +L SP + LD R L ++ +++D TS + SP S + +S S Sbjct: 89 KTKTEQELPRPQSPSD-LDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDS 147 Query: 605 DKEDKPPLAPSGGTEGPEQP--PPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPN 662 SG ++GP +P PPP + PP + P A ++ P Sbjct: 148 S---------SGLSQGPARPYHPPPLFPPSPQPP------DSTPRQPEASFEPHPSVTPT 192 Query: 663 AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722 P + ++ P P+ + + VL+ G S + + G Sbjct: 193 GYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQ 252 Query: 723 VQAPQMYPYPVSNSVPGQQGKYR----------GAKGSLPPQRSDQHQPASAPPMMQAA- 771 P P+S S G G G S PP + H + PP Sbjct: 253 HPPPTT---PISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRP 309 Query: 772 ---AAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRML--- 825 A+A PP + A P P P AM Q M P P P L +P L Sbjct: 310 LNNASASPPGLGAQPL-------PGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPA 362 Query: 826 -------------TSGSHPQAIVSSSTPQYPSAEQPTP--QALYATVHQSYPHHATQLHA 870 +S S A SSS+ S+ P P QAL SYPH Sbjct: 363 SSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQAL-----PSYPHSF----- 412 Query: 871 HQPQPATTPTGSQPQ--SQHAAPSPVQHQAGQAPHLGSGQPQQNLY-HPGALTGTPPSLP 927 P P + +QP +Q + PS G P G+ N HPG Sbjct: 413 --PPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPG---------- 460 Query: 928 PGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQ 987 P P + QS+ P + + HHQQ Q Q + PPP PHP Sbjct: 461 PFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHP-- 518 Query: 988 VMLLHPPQSHGGPPQGAVPQSG----VPALSASTPSPYPYIGHPQGEQPG 1033 L SH P P G P A P P+ + + Q G Sbjct: 519 ---LEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNG 565 Score = 65.1 bits (157), Expect = 3e-10 Identities = 146/633 (23%), Positives = 197/633 (31%), Gaps = 114/633 (18%) Query: 371 GGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS 430 GG G+ S PP GP G S G NGG P + + +P +P Sbjct: 222 GGTGGVLSGPPMGP-----KGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKP- 275 Query: 431 GETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVG 490 P VG P +P A ++ + P PP + +SAS P + PG Sbjct: 276 ------PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPG-- 327 Query: 491 SISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGA 550 P+ + + K P P L + P RF A Sbjct: 328 -HLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPA---PPMRFPYSSSSSSSA 383 Query: 551 QFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKP 610 SSS +S PFP L S P P P Sbjct: 384 AAS-SSSSSSSSSASPFP--------------ASQALPSYPHSFP--------------P 414 Query: 611 PLAPSGGTEGPEQPPPPCPSQT----GSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEF 666 P + S + P+ P PSQ G PP P + S +P Sbjct: 415 PTSLSVSNQPPKYTQPSLPSQAVWSQGPPP----------PPPYGRLLANSNAHP----- 459 Query: 667 NPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAP 726 P P + P S H Q Q Q H P Sbjct: 460 GPFPPSTGAQSTAHPPVSTHHHHHQQQQ-------QQQQQQQQQQQQQQQHHGNSGPPPP 512 Query: 727 QMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPP-----MMQAAAAAGPPLVAA 781 +P+P+ Y SL R PA PP A GPP+ ++ Sbjct: 513 GAFPHPLEGGSSHHAHPY-AMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSS 571 Query: 782 TPYSSYIPYN--PQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSST 839 + SS P P P+ A YP PV P + ++ L S A V+SS Sbjct: 572 SNSSSSTSQGSYPCSHP-SPSQGPQGAPYPFPPV--PTVTTSSATL---STVIATVASSP 625 Query: 840 PQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAG 899 Y +A P P P + + + TP G +P SP + G Sbjct: 626 AGYKTASPPGP-----------PPYGKRAPSPGAYKTATPPGYKP------GSPPSFRTG 668 Query: 900 QAP-HLGSGQPQ-QNLYHPGALTGTPPSLPP-GPSAQSPQSSFPQPAAVYAIHHQQLPHG 956 P + G+ P + PG+ T P LPP GPS S P P A A P Sbjct: 669 TPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSG---LPSLPPPPAAPA---SGPPLS 722 Query: 957 FTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVM 989 T + +T + PP +P PP+V+ Sbjct: 723 ATQIKQEPAEEYETPESPVPPARSPSP-PPKVV 754 Score = 60.1 bits (144), Expect = 1e-08 Identities = 131/564 (23%), Positives = 178/564 (31%), Gaps = 123/564 (21%) Query: 359 GPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNS----SPGPGSEARGINGG---------- 404 GP+GG SS G G PP P + +S +P + GG Sbjct: 234 GPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPAN 293 Query: 405 -----PSRMSPKAQRPLRGAKT-------------LSSPSNRPSGETSVPPPPAVGRMYP 446 P+ P A RPL A L SP G +PP P G Sbjct: 294 FPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLA 353 Query: 447 PRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDV 506 P SP S PA S+S P PP+ P +SS S S S +S S +P Sbjct: 354 P-SPHSLPPA--SSSAPAPPM---------RFPYSSSSSSSAAASSSSSSSSSSASPFPA 401 Query: 507 KELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSL-- 564 + P P L+ + N+ ++ L + P P L Sbjct: 402 SQALPSYPHSFPPPTSLS--------VSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLA 453 Query: 565 ------DPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSS-----KTESVSDKEDKPPLA 613 PFPP T+ P PVS+ + + ++ + Sbjct: 454 NSNAHPGPFPP------------STGAQSTAHP---PVSTHHHHHQQQQQQQQQQQQQQQ 498 Query: 614 PSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLL 673 G PPPP G+ P L G P A +L P P P Sbjct: 499 QQQQHHGNSGPPPP-----GAFPHPLEGGSSHHAHPYAMSPSLGSLRP-----YPPGP-- 546 Query: 674 SVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP- 732 P S + + P+ P +++ + S SY P H P+ Q PQ PYP Sbjct: 547 ---AHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSY-PCSHPSPS-QGPQGAPYPF 601 Query: 733 ------------VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAG----- 775 +S + G K + PP + A +P + A G Sbjct: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS 661 Query: 776 -PPLVAATP---YSSYIPYNPQQF-PGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSH 830 P TP + P P F PG P + P P+ P P L P SG Sbjct: 662 PPSFRTGTPPGYRGTSPPAGPGTFKPGSPT-VGPGPLPPAGPSGLPSLPPPPAAPASGPP 720 Query: 831 PQAIVSSSTP--QYPSAEQPTPQA 852 A P +Y + E P P A Sbjct: 721 LSATQIKQEPAEEYETPESPVPPA 744 Score = 40.8 bits (94), Expect = 0.007 Identities = 133/590 (22%), Positives = 201/590 (34%), Gaps = 102/590 (17%) Query: 351 PLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSP 410 P P R G + ++ G +PG P +P PG GP P Sbjct: 636 PPPYGKRAPSPGAYKTATPPGYKPG-------SPPSFRTGTP-PGYRGTSPPAGPGTFKP 687 Query: 411 KAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKS------------AAPAPI 458 + P G L P PSG S+PPPPA PP S +P P Sbjct: 688 GS--PTVGPGPL--PPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPP 743 Query: 459 SASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRT- 517 + S PP VP+ ++ + D G S A + P + +L+ K Sbjct: 744 ARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSC--ARSDLYFVPLEGSKLAKKRADLVE 801 Query: 518 ---LEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKL-QPSSSPEN--SLDPFPPRI 571 E ++ AR + + +K + E+ R+ KL Q +P SL P P R Sbjct: 802 KVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRP 861 Query: 572 LKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPC--P 629 E + T P P + ++S+ +P + G P P P Sbjct: 862 PFEPG-------SAVATVPPYLGPDTPALRTLSEYA-RPHVMSPGNRNHPFYVPLGAVDP 913 Query: 630 SQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTS--PGP 687 G L + P A + ++ + ++ KP V S P PGP Sbjct: 914 GLLGYNVPALYSSD-----PAAREREREARERDLRD--RLKPGFEVKPSELEPLHGVPGP 966 Query: 688 RTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQ--APQMYPYPVSNSV-PGQQGKY 744 P H G A+Q P ++P+P S+ P ++ + Sbjct: 967 GLDPFPR-----------------------HGGLALQPGPPGLHPFPFHPSLGPLERERL 1003 Query: 745 RGAKG-SLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQ--QFPGQPAM 801 A G +L P S + A+ + AA G +A + P++ Q + Sbjct: 1004 ALAAGPALRPDMSYAERLAAERQHAERVAALGNDPLARLQMLNVTPHHHQHSHIHSHLHL 1063 Query: 802 MQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSY 861 Q A + + P++ L SGSH I YP+ P P + Sbjct: 1064 HQQDAIHAASASVHPLIDP----LASGSHLTRI------PYPAGTLPNPLL-------PH 1106 Query: 862 PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQ 911 P H ++ HQ A P P S +AP HQ QA H S + Q+ Sbjct: 1107 PLHENEVLRHQLFAA--PYRDLPASL-SAPMSAAHQL-QAMHAQSAELQR 1152 Score = 40.4 bits (93), Expect = 0.009 Identities = 68/298 (22%), Positives = 92/298 (30%), Gaps = 41/298 (13%) Query: 385 HHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRM 444 HH ++ P PG+ + GG S + P + +L S P G +PPP Sbjct: 503 HHGNSGPPPPGAFPHPLEGGSSHHA----HPYAMSPSLGSLRPYPPGPAHLPPP------ 552 Query: 445 YPPRSPKSAAP--APISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLA 502 + S A P P+S+S S+ TS S P + G P + Sbjct: 553 HSQVSYSQAGPNGPPVSSSS-----NSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTV 607 Query: 503 PTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN 562 T LST T+ PG KR K +P S Sbjct: 608 TTSSATLSTVIA--TVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS---- 661 Query: 563 SLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPE 622 PP P G TS P G PP PSG P Sbjct: 662 -----PPSFRTGTPPGYRG------TSPPAGPGTFKPGSPTVGPGPLPPAGPSGL---PS 707 Query: 623 QPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTS 680 PPPP +G P + + P E + P A+ +P ++ V S Sbjct: 708 LPPPPAAPASGPP----LSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHAS 761 Score = 37.0 bits (84), Expect = 0.10 Identities = 31/95 (32%), Positives = 37/95 (38%), Gaps = 18/95 (18%) Query: 12 QPQQPPPTQQAVARRPPG--GTSPPNGGL----------PGPL---ATSAAPPGPPAAAS 56 +P PP + PPG GTSPP G PGPL S P PP A+ Sbjct: 658 KPGSPPSFRTGT---PPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAA 714 Query: 57 PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERP 91 P GP +A + AE P+ P P P Sbjct: 715 PASGPPLSATQIKQEPAEEYETPESPVPPARSPSP 749 Score = 35.8 bits (81), Expect = 0.22 Identities = 22/52 (42%), Positives = 25/52 (48%), Gaps = 6/52 (11%) Query: 4 PQPLQQ--PSQPQQ-PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPP 52 P P Q PS P PPPT +V+ +PP T P LP S PP PP Sbjct: 398 PFPASQALPSYPHSFPPPTSLSVSNQPPKYTQP---SLPSQAVWSQGPPPPP 446 Score = 35.8 bits (81), Expect = 0.22 Identities = 32/104 (30%), Positives = 37/104 (35%), Gaps = 19/104 (18%) Query: 8 QQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGS 67 QQ Q QQ QQ + PP G P PL ++ P A SP LG Sbjct: 485 QQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGS------ 538 Query: 68 GLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111 L P PP P H P + S G + GPP S Sbjct: 539 ---------LRPYPPGP-AHLPPPHSQVSYSQAGPN---GPPVS 569 Score = 33.9 bits (76), Expect = 0.85 Identities = 34/113 (30%), Positives = 42/113 (37%), Gaps = 16/113 (14%) Query: 4 PQPLQQPS-QPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPV 62 P PL PS QP P Q + P +P P TS PP A P P Sbjct: 161 PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPP--HPQ 218 Query: 63 AAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK--GPPQSPV 113 G G G+L+ P P+ G A S G + GK PP +P+ Sbjct: 219 LYPG-----GTGGVLSGPPMGPK------GGGAASSVGGPNGGKQHPPPTTPI 260 Score = 33.1 bits (74), Expect = 1.4 Identities = 28/96 (29%), Positives = 31/96 (32%), Gaps = 3/96 (3%) Query: 14 QQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGA 73 Q PPPT +PP P+ P PP A P + P LR Sbjct: 252 QHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLN 311 Query: 74 EGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109 A PP Q PG A GQ G PP Sbjct: 312 N---ASASPPGLGAQPLPGHLPSPHAMGQGMGGLPP 344 >gi|55750041 atrophin-1 [Homo sapiens] Length = 1190 Score = 77.0 bits (188), Expect = 9e-14 Identities = 138/590 (23%), Positives = 198/590 (33%), Gaps = 101/590 (17%) Query: 490 GSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEEL---R 546 G SP +S + +D K +++ + +E + G E + EE + Sbjct: 31 GRASPGG--VSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPK 88 Query: 547 KFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD--GLLTSEPMGSPVSSKTESVS 604 K + +L SP + LD R L ++ +++D TS + SP S + +S S Sbjct: 89 KTKTEQELPRPQSPSD-LDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDS 147 Query: 605 DKEDKPPLAPSGGTEGPEQP--PPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPN 662 SG ++GP +P PPP + PP + P A ++ P Sbjct: 148 S---------SGLSQGPARPYHPPPLFPPSPQPP------DSTPRQPEASFEPHPSVTPT 192 Query: 663 AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722 P + ++ P P+ + + VL+ G S + + G Sbjct: 193 GYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQ 252 Query: 723 VQAPQMYPYPVSNSVPGQQGKYR----------GAKGSLPPQRSDQHQPASAPPMMQAA- 771 P P+S S G G G S PP + H + PP Sbjct: 253 HPPPTT---PISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRP 309 Query: 772 ---AAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRML--- 825 A+A PP + A P P P AM Q M P P P L +P L Sbjct: 310 LNNASASPPGLGAQPL-------PGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPA 362 Query: 826 -------------TSGSHPQAIVSSSTPQYPSAEQPTP--QALYATVHQSYPHHATQLHA 870 +S S A SSS+ S+ P P QAL SYPH Sbjct: 363 SSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQAL-----PSYPHSF----- 412 Query: 871 HQPQPATTPTGSQPQ--SQHAAPSPVQHQAGQAPHLGSGQPQQNLY-HPGALTGTPPSLP 927 P P + +QP +Q + PS G P G+ N HPG Sbjct: 413 --PPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPG---------- 460 Query: 928 PGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQ 987 P P + QS+ P + + HHQQ Q Q + PPP PHP Sbjct: 461 PFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHP-- 518 Query: 988 VMLLHPPQSHGGPPQGAVPQSG----VPALSASTPSPYPYIGHPQGEQPG 1033 L SH P P G P A P P+ + + Q G Sbjct: 519 ---LEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNG 565 Score = 65.1 bits (157), Expect = 3e-10 Identities = 146/633 (23%), Positives = 197/633 (31%), Gaps = 114/633 (18%) Query: 371 GGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS 430 GG G+ S PP GP G S G NGG P + + +P +P Sbjct: 222 GGTGGVLSGPPMGP-----KGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKP- 275 Query: 431 GETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVG 490 P VG P +P A ++ + P PP + +SAS P + PG Sbjct: 276 ------PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPG-- 327 Query: 491 SISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGA 550 P+ + + K P P L + P RF A Sbjct: 328 -HLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPA---PPMRFPYSSSSSSSA 383 Query: 551 QFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKP 610 SSS +S PFP L S P P P Sbjct: 384 AAS-SSSSSSSSSASPFP--------------ASQALPSYPHSFP--------------P 414 Query: 611 PLAPSGGTEGPEQPPPPCPSQT----GSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEF 666 P + S + P+ P PSQ G PP P + S +P Sbjct: 415 PTSLSVSNQPPKYTQPSLPSQAVWSQGPPP----------PPPYGRLLANSNAHP----- 459 Query: 667 NPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAP 726 P P + P S H Q Q Q H P Sbjct: 460 GPFPPSTGAQSTAHPPVSTHHHHHQQQQ-------QQQQQQQQQQQQQQQHHGNSGPPPP 512 Query: 727 QMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPP-----MMQAAAAAGPPLVAA 781 +P+P+ Y SL R PA PP A GPP+ ++ Sbjct: 513 GAFPHPLEGGSSHHAHPY-AMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSS 571 Query: 782 TPYSSYIPYN--PQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSST 839 + SS P P P+ A YP PV P + ++ L S A V+SS Sbjct: 572 SNSSSSTSQGSYPCSHP-SPSQGPQGAPYPFPPV--PTVTTSSATL---STVIATVASSP 625 Query: 840 PQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAG 899 Y +A P P P + + + TP G +P SP + G Sbjct: 626 AGYKTASPPGP-----------PPYGKRAPSPGAYKTATPPGYKP------GSPPSFRTG 668 Query: 900 QAP-HLGSGQPQ-QNLYHPGALTGTPPSLPP-GPSAQSPQSSFPQPAAVYAIHHQQLPHG 956 P + G+ P + PG+ T P LPP GPS S P P A A P Sbjct: 669 TPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSG---LPSLPPPPAAPA---SGPPLS 722 Query: 957 FTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVM 989 T + +T + PP +P PP+V+ Sbjct: 723 ATQIKQEPAEEYETPESPVPPARSPSP-PPKVV 754 Score = 60.1 bits (144), Expect = 1e-08 Identities = 131/564 (23%), Positives = 178/564 (31%), Gaps = 123/564 (21%) Query: 359 GPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNS----SPGPGSEARGINGG---------- 404 GP+GG SS G G PP P + +S +P + GG Sbjct: 234 GPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPAN 293 Query: 405 -----PSRMSPKAQRPLRGAKT-------------LSSPSNRPSGETSVPPPPAVGRMYP 446 P+ P A RPL A L SP G +PP P G Sbjct: 294 FPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLA 353 Query: 447 PRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDV 506 P SP S PA S+S P PP+ P +SS S S S +S S +P Sbjct: 354 P-SPHSLPPA--SSSAPAPPM---------RFPYSSSSSSSAAASSSSSSSSSSASPFPA 401 Query: 507 KELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSL-- 564 + P P L+ + N+ ++ L + P P L Sbjct: 402 SQALPSYPHSFPPPTSLS--------VSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLA 453 Query: 565 ------DPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSS-----KTESVSDKEDKPPLA 613 PFPP T+ P PVS+ + + ++ + Sbjct: 454 NSNAHPGPFPP------------STGAQSTAHP---PVSTHHHHHQQQQQQQQQQQQQQQ 498 Query: 614 PSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLL 673 G PPPP G+ P L G P A +L P P P Sbjct: 499 QQQQHHGNSGPPPP-----GAFPHPLEGGSSHHAHPYAMSPSLGSLRP-----YPPGP-- 546 Query: 674 SVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP- 732 P S + + P+ P +++ + S SY P H P+ Q PQ PYP Sbjct: 547 ---AHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSY-PCSHPSPS-QGPQGAPYPF 601 Query: 733 ------------VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAG----- 775 +S + G K + PP + A +P + A G Sbjct: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS 661 Query: 776 -PPLVAATP---YSSYIPYNPQQF-PGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSH 830 P TP + P P F PG P + P P+ P P L P SG Sbjct: 662 PPSFRTGTPPGYRGTSPPAGPGTFKPGSPT-VGPGPLPPAGPSGLPSLPPPPAAPASGPP 720 Query: 831 PQAIVSSSTP--QYPSAEQPTPQA 852 A P +Y + E P P A Sbjct: 721 LSATQIKQEPAEEYETPESPVPPA 744 Score = 40.8 bits (94), Expect = 0.007 Identities = 133/590 (22%), Positives = 201/590 (34%), Gaps = 102/590 (17%) Query: 351 PLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSP 410 P P R G + ++ G +PG P +P PG GP P Sbjct: 636 PPPYGKRAPSPGAYKTATPPGYKPG-------SPPSFRTGTP-PGYRGTSPPAGPGTFKP 687 Query: 411 KAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKS------------AAPAPI 458 + P G L P PSG S+PPPPA PP S +P P Sbjct: 688 GS--PTVGPGPL--PPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPP 743 Query: 459 SASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRT- 517 + S PP VP+ ++ + D G S A + P + +L+ K Sbjct: 744 ARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSC--ARSDLYFVPLEGSKLAKKRADLVE 801 Query: 518 ---LEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKL-QPSSSPEN--SLDPFPPRI 571 E ++ AR + + +K + E+ R+ KL Q +P SL P P R Sbjct: 802 KVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRP 861 Query: 572 LKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPC--P 629 E + T P P + ++S+ +P + G P P P Sbjct: 862 PFEPG-------SAVATVPPYLGPDTPALRTLSEYA-RPHVMSPGNRNHPFYVPLGAVDP 913 Query: 630 SQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTS--PGP 687 G L + P A + ++ + ++ KP V S P PGP Sbjct: 914 GLLGYNVPALYSSD-----PAAREREREARERDLRD--RLKPGFEVKPSELEPLHGVPGP 966 Query: 688 RTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQ--APQMYPYPVSNSV-PGQQGKY 744 P H G A+Q P ++P+P S+ P ++ + Sbjct: 967 GLDPFPR-----------------------HGGLALQPGPPGLHPFPFHPSLGPLERERL 1003 Query: 745 RGAKG-SLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQ--QFPGQPAM 801 A G +L P S + A+ + AA G +A + P++ Q + Sbjct: 1004 ALAAGPALRPDMSYAERLAAERQHAERVAALGNDPLARLQMLNVTPHHHQHSHIHSHLHL 1063 Query: 802 MQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSY 861 Q A + + P++ L SGSH I YP+ P P + Sbjct: 1064 HQQDAIHAASASVHPLIDP----LASGSHLTRI------PYPAGTLPNPLL-------PH 1106 Query: 862 PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQ 911 P H ++ HQ A P P S +AP HQ QA H S + Q+ Sbjct: 1107 PLHENEVLRHQLFAA--PYRDLPASL-SAPMSAAHQL-QAMHAQSAELQR 1152 Score = 40.4 bits (93), Expect = 0.009 Identities = 68/298 (22%), Positives = 92/298 (30%), Gaps = 41/298 (13%) Query: 385 HHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRM 444 HH ++ P PG+ + GG S + P + +L S P G +PPP Sbjct: 503 HHGNSGPPPPGAFPHPLEGGSSHHA----HPYAMSPSLGSLRPYPPGPAHLPPP------ 552 Query: 445 YPPRSPKSAAP--APISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLA 502 + S A P P+S+S S+ TS S P + G P + Sbjct: 553 HSQVSYSQAGPNGPPVSSSS-----NSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTV 607 Query: 503 PTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN 562 T LST T+ PG KR K +P S Sbjct: 608 TTSSATLSTVIA--TVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS---- 661 Query: 563 SLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPE 622 PP P G TS P G PP PSG P Sbjct: 662 -----PPSFRTGTPPGYRG------TSPPAGPGTFKPGSPTVGPGPLPPAGPSGL---PS 707 Query: 623 QPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTS 680 PPPP +G P + + P E + P A+ +P ++ V S Sbjct: 708 LPPPPAAPASGPP----LSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHAS 761 Score = 37.0 bits (84), Expect = 0.10 Identities = 31/95 (32%), Positives = 37/95 (38%), Gaps = 18/95 (18%) Query: 12 QPQQPPPTQQAVARRPPG--GTSPPNGGL----------PGPL---ATSAAPPGPPAAAS 56 +P PP + PPG GTSPP G PGPL S P PP A+ Sbjct: 658 KPGSPPSFRTGT---PPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAA 714 Query: 57 PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERP 91 P GP +A + AE P+ P P P Sbjct: 715 PASGPPLSATQIKQEPAEEYETPESPVPPARSPSP 749 Score = 35.8 bits (81), Expect = 0.22 Identities = 22/52 (42%), Positives = 25/52 (48%), Gaps = 6/52 (11%) Query: 4 PQPLQQ--PSQPQQ-PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPP 52 P P Q PS P PPPT +V+ +PP T P LP S PP PP Sbjct: 398 PFPASQALPSYPHSFPPPTSLSVSNQPPKYTQP---SLPSQAVWSQGPPPPP 446 Score = 35.8 bits (81), Expect = 0.22 Identities = 32/104 (30%), Positives = 37/104 (35%), Gaps = 19/104 (18%) Query: 8 QQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGS 67 QQ Q QQ QQ + PP G P PL ++ P A SP LG Sbjct: 485 QQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGS------ 538 Query: 68 GLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111 L P PP P H P + S G + GPP S Sbjct: 539 ---------LRPYPPGP-AHLPPPHSQVSYSQAGPN---GPPVS 569 Score = 33.9 bits (76), Expect = 0.85 Identities = 34/113 (30%), Positives = 42/113 (37%), Gaps = 16/113 (14%) Query: 4 PQPLQQPS-QPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPV 62 P PL PS QP P Q + P +P P TS PP A P P Sbjct: 161 PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPP--HPQ 218 Query: 63 AAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK--GPPQSPV 113 G G G+L+ P P+ G A S G + GK PP +P+ Sbjct: 219 LYPG-----GTGGVLSGPPMGPK------GGGAASSVGGPNGGKQHPPPTTPI 260 Score = 33.1 bits (74), Expect = 1.4 Identities = 28/96 (29%), Positives = 31/96 (32%), Gaps = 3/96 (3%) Query: 14 QQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGA 73 Q PPPT +PP P+ P PP A P + P LR Sbjct: 252 QHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLN 311 Query: 74 EGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109 A PP Q PG A GQ G PP Sbjct: 312 N---ASASPPGLGAQPLPGHLPSPHAMGQGMGGLPP 344 >gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] Length = 2217 Score = 73.9 bits (180), Expect = 7e-13 Identities = 126/492 (25%), Positives = 167/492 (33%), Gaps = 85/492 (17%) Query: 621 PEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTS 680 P PPP P TG G+ G + + T P P PL V Sbjct: 708 PVLPPPSTPMPTGP-------GQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPV----- 755 Query: 681 TPTSPGPRTHSTPSIPVLTAGQSGLYSPQYIS--YIPQIHMGPAVQAP-QMYPYPVSNSV 737 P +P A S + +P + +PQ + P Q P QM P PV + Sbjct: 756 -----------PPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPI 804 Query: 738 PGQQGKYRGAKGSLPPQRSDQHQ---PASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQ 794 G LPP D P PP + A P L A P +S P P Q Sbjct: 805 TPLAGI-----DGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPAS--PALPLQ 857 Query: 795 F------PGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVS-SSTPQYPSAEQ 847 PG P M P+ P P+L P + + S A+ P YP+A Sbjct: 858 AVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAA-- 915 Query: 848 PTPQALYATVHQSYPHHATQ-LHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGS 906 PQ V S PHH Q + A PQPA P + P P P P + Sbjct: 916 -FPQMAPTDVPPS-PHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPT 973 Query: 907 GQPQQNLYHPGALTGTPPSLPPGPS----AQSPQSSFPQPAAVYAIHHQQL------PHG 956 +P Q + P + P LPP P+ + Q P+ AA A Q+ P+ Sbjct: 974 -RPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYA 1032 Query: 957 FTNMAHVTQAHVQTGITAAPP-PHPGAPHPPQVMLLH--------------PPQSHGGPP 1001 A V V +PP P P P+++ P Q+ P Sbjct: 1033 VDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLP 1092 Query: 1002 QGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQ--APGFP------GGAD---DRIREFS 1050 P G P +++ P+ + Q EQ Q PG P GG+D + S Sbjct: 1093 PANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGGSDVTSGKELSDS 1152 Query: 1051 LAGGIWHGRAEG 1062 G GR EG Sbjct: 1153 CEGAFGGGRLEG 1164 Score = 46.6 bits (109), Expect = 1e-04 Identities = 74/270 (27%), Positives = 88/270 (32%), Gaps = 42/270 (15%) Query: 770 AAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGS 829 A AA P +P S P PQ P A QP A P PV + + P L Sbjct: 641 ADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTA-APGLPVGSVPAPACPPSLQQHF 699 Query: 830 HPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHA 889 A+ + PS PT A Q QP P PT P Q Sbjct: 700 PDPAMSFAPVLPPPSTPMPTGPGQPAPPGQ------------QPPPLAQPT---PLPQVL 744 Query: 890 APSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIH 949 AP PV PHL P + G P L P Q+P QP A Sbjct: 745 APQPVVPLQPVPPHL------PPYLAPASQVGAPAQLKPLQMPQAPL----QPLA----- 789 Query: 950 HQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSG 1009 Q+P + V GI PP P P PP PPQ P Sbjct: 790 --QVPPQMPPIPVVPPITPLAGIDGLPPALPDLP-----TATVPPVP---PPQYFSPAVI 839 Query: 1010 VPALSASTPSPYPYIGHPQGEQPGQAPGFP 1039 +P+L+A P P + + P PG P Sbjct: 840 LPSLAAPLPPASPALPLQAVKLP-HPPGAP 868 Score = 45.4 bits (106), Expect = 3e-04 Identities = 53/179 (29%), Positives = 70/179 (39%), Gaps = 21/179 (11%) Query: 352 LPQRVREGPRG----GVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSR 407 +P + E RG G+ ++ RPG R D P PG EA G P Sbjct: 10 VPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEP-PGLEAAEAPG-PQP 67 Query: 408 MSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA-VGRMYPPRSPKSAAPAPISASCPEP- 465 P +R L KT + R G + P P A V + P +P A P P+ P P Sbjct: 68 PQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGPD 127 Query: 466 PIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTL--EPQE 522 PI +AV T+ A P G A+ + E + EPGRT EP+E Sbjct: 128 PIAAAVETAPA----------PDGGPREEAAATVRKEDEGAAE-AKPEPGRTRRDEPEE 175 Score = 42.4 bits (98), Expect = 0.002 Identities = 78/303 (25%), Positives = 108/303 (35%), Gaps = 46/303 (15%) Query: 736 SVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSY-IPYNPQQ 794 S PG + G + S Q Q A+AP Q G P + + P P+ Sbjct: 1271 SDPGTSPPHLSTCGLGTGEESRQSQ-ANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPES 1329 Query: 795 FPGQP-AMMQPMAHYPSQPVFAPMLQSN--PRMLTSGSHPQAIVSSSTPQYPSAEQPTPQ 851 P P + + P A S P + L S P L S Q ++S + P P P P Sbjct: 1330 SPPLPLSSLPPEASQDSAP-YKDQLSSKEQPSFLAS----QQLLSQAGPSNPPGAPPAPL 1384 Query: 852 ALYATVHQSYPHH-ATQLHAHQPQPAT----------TPTG-------SQPQSQ-HAAPS 892 A + + P A + P+PA+ TP G SQP ++ H AP Sbjct: 1385 APSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPL 1444 Query: 893 PVQHQA-GQAPHLGSGQPQQNLYHPGALTGTPPSLP-PGPSAQSPQSSFPQPAAVYAIHH 950 VQ G AP + + PP P P P + +PQ + QPA + Sbjct: 1445 AVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPL----- 1499 Query: 951 QQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGV 1010 LP A V + T +PP P P P L G PP+ S + Sbjct: 1500 --LP------AAVGAVSLATSQLPSPPLGPTVPPQPPSAL--ESDGEGPPPRVGFVDSTI 1549 Query: 1011 PAL 1013 +L Sbjct: 1550 KSL 1552 Score = 42.0 bits (97), Expect = 0.003 Identities = 179/825 (21%), Positives = 273/825 (33%), Gaps = 171/825 (20%) Query: 1 MLKPQPL--QQPSQPQQPPPTQQAVARRPPGGTSPPNG---GLPGPLATSAAP-----PG 50 ML PQP+ QP+ P +P P Q + + +P + G P P A A P Sbjct: 985 MLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPV 1044 Query: 51 PPAA------------ASPCLGP--------VAAAGSGLRRGAEGILAPQPPPPQQHQER 90 PPAA A+P L P V+A+ + +L P PP Sbjct: 1045 PPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPP------L 1098 Query: 91 PGAAAIGSA------------RGQSTGKGPPQSPVFEGVYNNSRMLHFLTAVVGSTCDVK 138 PG I S Q++ PP P Y S + + +C+ Sbjct: 1099 PGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGGSDVTS--GKELSDSCE-- 1154 Query: 139 VKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRRE-----DIVDTMV---FKPSDV 190 G G + +++ R E A PR + D MV + + Sbjct: 1155 ---GAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDKMVECQLETHNH 1211 Query: 191 MLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDDYDLESDMSNG 250 +V F+ D + D+ + + + E + + Q + D D ++D G Sbjct: 1212 KMVTFK-FDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDMLSEDTDADRG 1270 Query: 251 WDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLAREI-----ES 305 DP + G+ T +S S P+ + N +R +A ES Sbjct: 1271 SDPGTSPP-HLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPES 1329 Query: 306 SPQYRLRIAMENDDGRTEEEKHSAVQR-QGSGRESPS-LASREGKYIPLPQRVREGPRGG 363 SP L E + SA + Q S +E PS LAS++ P P Sbjct: 1330 SPPLPLSSLPP------EASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAP 1383 Query: 364 VRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGP------------------ 405 + SS P +++LP G ++ P P S GGP Sbjct: 1384 LAPSS-----PPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAE 1438 Query: 406 SRMSPKAQRPLRG--AKTLSSPSNRPSGETSVP----PPPAVGRMYPPRSPKSAAPAPI- 458 + +P A +PL A +P + + S P PPPA P SP S P P Sbjct: 1439 THEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPA-----PEPSPHSGTPQPAL 1493 Query: 459 -----------------SASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISL 501 ++ P PP+G VP S + P P++ Sbjct: 1494 GQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPP---------PRVGF 1544 Query: 502 APTDVKELSTKEPGRTLEPQELARIAGKVPGLQNE--QKRFQLEELRKFGAQFKLQPSSS 559 + +K L K RTL QE + G E + F LE LR G Q + + Sbjct: 1545 VDSTIKSLDEKL--RTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLR--GDQPRSEVCGG 1600 Query: 560 PENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTE 619 + +L P P + + + V+ + G+ + T S E P + Sbjct: 1601 -DLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRD 1659 Query: 620 GPE--QPPPPCPSQTGSPPV----GLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLL 673 G + PS P ++ D+D G E S+ P P + Sbjct: 1660 GRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGE----SSAEP------PPSDMG 1709 Query: 674 SVNKSTSTPTSPGPRTHSTP---------SIPVLTAGQSGLYSPQ 709 +V S P + G R +P S P T G+ + S Q Sbjct: 1710 TVGGQASHPQTLGARALGSPRKRPEQQDVSSPAKTVGRFSVVSTQ 1754 Score = 35.8 bits (81), Expect = 0.22 Identities = 39/149 (26%), Positives = 60/149 (40%), Gaps = 16/149 (10%) Query: 376 LSSLPPRGPHHLDNSSP-GPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRP-SGET 433 L +PP P +L +S G ++ + + + + P AQ P + P P +G Sbjct: 752 LQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGID 811 Query: 434 SVPP-----PPAVGRMYPPRSPKSAAPAPI--SASCPEPPIGSAVPTSSASIPVTSSVSD 486 +PP P A PP P+ +PA I S + P PP A+P + +P Sbjct: 812 GLPPALPDLPTATVPPVPP--PQYFSPAVILPSLAAPLPPASPALPLQAVKLP-----HP 864 Query: 487 PGVGSISPASPKISLAPTDVKELSTKEPG 515 PG P + AP + L+ PG Sbjct: 865 PGAPLAMPCRTIVPNAPATIPLLAVAPPG 893 Score = 35.0 bits (79), Expect = 0.38 Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 8/85 (9%) Query: 12 QPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAA-----SPCLGPVAAAG 66 +P P P A+ +P +P + G P P+ T P P AAA +P GP A Sbjct: 92 RPAAPAPA--ALVAQPGAPGAPADAG-PEPVGTQEPGPDPIAAAVETAPAPDGGPREEAA 148 Query: 67 SGLRRGAEGILAPQPPPPQQHQERP 91 + +R+ EG +P P + ++ P Sbjct: 149 ATVRKEDEGAAEAKPEPGRTRRDEP 173 Score = 33.5 bits (75), Expect = 1.1 Identities = 36/137 (26%), Positives = 50/137 (36%), Gaps = 18/137 (13%) Query: 910 QQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQ---- 965 QQN+ H G + P+ ++P+SS P P + Q + + + Sbjct: 1302 QQNVLHTGKRWFIICPVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSF 1361 Query: 966 -AHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYI 1024 A Q A P PGAP P P S PP A+PQ G +++ P P Sbjct: 1362 LASQQLLSQAGPSNPPGAPPAPLA-----PSS---PPVTALPQDGAAPATSTMPEPASGT 1413 Query: 1025 GHPQGEQPGQAPGFPGG 1041 G PG P G Sbjct: 1414 ASQAG-----GPGTPQG 1425 Score = 33.1 bits (74), Expect = 1.4 Identities = 60/249 (24%), Positives = 90/249 (36%), Gaps = 50/249 (20%) Query: 315 MENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGPRGG-VRCSSSRGGR 373 ME + + S G R+ +AS +PQ V R V + GG Sbjct: 1636 MEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGE 1695 Query: 374 PGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGET 433 G SS P P S+ + G S GA+ L SP RP + Sbjct: 1696 AGESSAEP------------PPSDMGTVGGQASHPQTL------GARALGSPRKRPEQQD 1737 Query: 434 SVPPPPAVGR-----------MYPPRSPKSAAPAPI----SASCPEPPIGSAVPTSSASI 478 P VGR + P S + +AP + + S P+ + +++SI Sbjct: 1738 VSSPAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSI 1797 Query: 479 ------PVTSSVSDPGVGSISPASPKISL------APTDVKELST--KEPGR--TLEPQE 522 PV+S D G + P + SL A VK+ + + P R +L P+ Sbjct: 1798 EVGVGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPET 1857 Query: 523 LARIAGKVP 531 +R+ KVP Sbjct: 1858 PSRVGMKVP 1866 Score = 32.0 bits (71), Expect = 3.2 Identities = 50/200 (25%), Positives = 71/200 (35%), Gaps = 31/200 (15%) Query: 622 EQPPPPCPSQTGSPPVGLIKGE-DKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTS 680 E P P P + P+ + E +D P +Q+ F ++ LLS ++ Sbjct: 1320 EHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSK----EQPSFLASQQLLSQAGPSN 1375 Query: 681 TPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQA-----PQMYPYPVSN 735 P +P P + S PV Q G + S +P+ G A QA PQ + Sbjct: 1376 PPGAP-PAPLAPSSPPVTALPQDG--AAPATSTMPEPASGTASQAGGPGTPQGLTSELET 1432 Query: 736 SVP---------GQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSS 786 S P Q G P + + ASAP PP +P+S Sbjct: 1433 SQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAP-----REPLPPPAPEPSPHSG 1487 Query: 787 YIPYNPQQFPGQPAMMQPMA 806 PQ GQPA + P A Sbjct: 1488 ----TPQPALGQPAPLLPAA 1503 Score = 31.6 bits (70), Expect = 4.2 Identities = 20/56 (35%), Positives = 20/56 (35%) Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASP 57 L PQP P P PT PP T PP LP P PP A P Sbjct: 944 LPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALP 999 Score = 30.8 bits (68), Expect = 7.2 Identities = 29/103 (28%), Positives = 41/103 (39%), Gaps = 10/103 (9%) Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464 P SP P A + P +P PP P R+ APA I Sbjct: 831 PQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATI------ 884 Query: 465 PPIGSAVPTSSASIPVTSSVSD-PGVGSISPASPKISLAPTDV 506 P+ + P A++ + S+V+ PG A P+ +APTDV Sbjct: 885 -PLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQ--MAPTDV 924 Score = 30.4 bits (67), Expect = 9.4 Identities = 23/74 (31%), Positives = 26/74 (35%), Gaps = 9/74 (12%) Query: 13 PQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRG 72 P P T Q + PP PP LP PP P P L P R Sbjct: 925 PPSPHHTVQNMRATPPQPALPPQPTLP---PQPVLPPQPTLPPQPVLPPQPT------RP 975 Query: 73 AEGILAPQPPPPQQ 86 + +L PQP P Q Sbjct: 976 PQPVLPPQPMLPPQ 989 Score = 30.4 bits (67), Expect = 9.4 Identities = 27/76 (35%), Positives = 29/76 (38%), Gaps = 16/76 (21%) Query: 10 PSQPQQPP-PTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSG 68 P QP PP PT PP T PP LP P T PP P P L P Sbjct: 939 PPQPALPPQPTLPPQPVLPPQPTLPPQPVLP-PQPT--RPPQPVLPPQPMLPP------- 988 Query: 69 LRRGAEGILAPQPPPP 84 + +L PQP P Sbjct: 989 -----QPVLPPQPALP 999 >gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo sapiens] Length = 1858 Score = 73.2 bits (178), Expect = 1e-12 Identities = 112/434 (25%), Positives = 151/434 (34%), Gaps = 67/434 (15%) Query: 651 AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQY 710 +EQ+ + + K P P L +STP +P + +P P G Y P + Sbjct: 1425 SEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSP--YRPHH 1482 Query: 711 ISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQA 770 S PQ+ G + PQ YP + ++P + G+L Q A+ Q Sbjct: 1483 -SQSPQV--GTPQREPQRNFYPAAQNLPANT--QQATSGTLFTQTPSGQSSATYSQFNQQ 1537 Query: 771 A--AAAGPPLVAATPYSSYIP----------YNP----------------QQFPGQPAMM 802 + + A PP P SSY YN Q PG + Sbjct: 1538 SLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQ 1597 Query: 803 QPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYP 862 H+ + F P NP + H Q + P P P P + S+ Sbjct: 1598 TVPGHHVTPGHFLP--SQNPTI-----HHQTAAAVVPPPPPPPPAPGPHLVQQP--NSHQ 1648 Query: 863 HHATQLHAHQPQPATTPTGSQPQSQHAA---------PSPVQHQAGQAPHLGSGQPQQNL 913 H+ H P A TP GS SQ A P P H PH +G Sbjct: 1649 QHSVA-HVVGPVHAVTP-GSHIHSQTAGHHLPPPPPPPGPAPHHH-PPPHPSTGLQGLQA 1705 Query: 914 YHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHH--QQLPHGFTNMAHVTQAHVQTG 971 H + PP PP P S +S + A+HH Q P F + AH T + Sbjct: 1706 QHQHVVNSAPPP-PPPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQ 1764 Query: 972 ITAAPPPHPGAPHPPQVMLLHPPQSHGGP---PQGAVPQSGVPALSASTPSPYP-YIGHP 1027 T PG H P H P GP PQG + +P +AS P+P + P Sbjct: 1765 ATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQG---PNSIPTPTASGFCPHPGSVALP 1821 Query: 1028 QGEQ-PGQAPGFPG 1040 G Q P QA PG Sbjct: 1822 HGVQGPQQASPVPG 1835 Score = 60.1 bits (144), Expect = 1e-08 Identities = 136/590 (23%), Positives = 205/590 (34%), Gaps = 109/590 (18%) Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASC---PEPPIGSAVPTSSAS 477 T PS S T PP +M P SP S PA P+P S V S A Sbjct: 1335 TNECPSPDTSQNTCKSPP----KMSKPGSPGSVIPAQAHGKIFTKPDPQWDSTVSASEAE 1390 Query: 478 --IPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQN 535 + + + + + + + A K T V+ S+++ + L P L+N Sbjct: 1391 NGVHLKTELQQKQLSNNNQALSKNHPPQTHVRN-SSEQLSQKLPSVPTKLHCPPSPHLEN 1449 Query: 536 EQKRFQLEE------------LRKFGAQFKLQPSSSPENSLDPFPPR-----ILKEEPKG 578 K ++ G+ ++ S SP+ P+ + P Sbjct: 1450 PPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPAN 1509 Query: 579 KEKEVDG-LLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQT---GS 634 ++ G L T P G SS T S +++ S + P PPPP PS + Sbjct: 1510 TQQATSGTLFTQTPSGQ--SSATYSQFNQQ-------SLNSTAPPPPPPPPPSSSYYQNQ 1560 Query: 635 PPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPS 694 P + ++ +G +++Q T PN ++ +TS T PG H TP Sbjct: 1561 QPSANFQNYNQLKGSLSQQT-VFTSGPNQ----------ALPGTTSQQTVPG--HHVTPG 1607 Query: 695 IPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVS---NSVPGQQGKYRGAK--G 749 L + ++ + +P P P + P S +SV G Sbjct: 1608 -HFLPSQNPTIHHQTAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGS 1666 Query: 750 SLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYP 809 + Q + H P PP GP P+ P+ G A Q + + Sbjct: 1667 HIHSQTAGHHLPPPPPP-------PGP-----APHHHPPPHPSTGLQGLQAQHQHVVNSA 1714 Query: 810 SQPVFAPMLQSNPRMLTSGSHPQAIVS------SSTPQYPSAEQPT--PQALYATVHQSY 861 P P S +L SG H + + P +PS+ PT P AT H + Sbjct: 1715 PPPPPPPPPSS---VLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHHTTL 1771 Query: 862 ----PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPG 917 H + H P P T P QPQ ++ P+P +G PH GS Sbjct: 1772 GPGPQHQPSGTGPHCPLPVTGP-HLQPQGPNSIPTPT--ASGFCPHPGS----------- 1817 Query: 918 ALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAH 967 +LP G Q PQ + P P + IH Q+P F N H + H Sbjct: 1818 ------VALPHG--VQGPQQASPVPGQI-PIHRAQVPPTFQNNYHGSGWH 1858 Score = 40.0 bits (92), Expect = 0.012 Identities = 37/151 (24%), Positives = 54/151 (35%), Gaps = 17/151 (11%) Query: 340 PSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEAR 399 PS G + Q + P G S P + P + HH ++ GPG + + Sbjct: 1723 PSSVLASGHHTTSAQALHHPPHQGPPLFPS-SAHPTVPPYPSQATHH---TTLGPGPQHQ 1778 Query: 400 GINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPIS 459 PS P P+ G P +P G S+P P A G + P A P + Sbjct: 1779 -----PSGTGPHCPLPVTG------PHLQPQGPNSIPTPTASG--FCPHPGSVALPHGVQ 1825 Query: 460 ASCPEPPIGSAVPTSSASIPVTSSVSDPGVG 490 P+ +P A +P T + G G Sbjct: 1826 GPQQASPVPGQIPIHRAQVPPTFQNNYHGSG 1856 >gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo sapiens] Length = 1858 Score = 73.2 bits (178), Expect = 1e-12 Identities = 112/434 (25%), Positives = 151/434 (34%), Gaps = 67/434 (15%) Query: 651 AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQY 710 +EQ+ + + K P P L +STP +P + +P P G Y P + Sbjct: 1425 SEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSP--YRPHH 1482 Query: 711 ISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQA 770 S PQ+ G + PQ YP + ++P + G+L Q A+ Q Sbjct: 1483 -SQSPQV--GTPQREPQRNFYPAAQNLPANT--QQATSGTLFTQTPSGQSSATYSQFNQQ 1537 Query: 771 A--AAAGPPLVAATPYSSYIP----------YNP----------------QQFPGQPAMM 802 + + A PP P SSY YN Q PG + Sbjct: 1538 SLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQ 1597 Query: 803 QPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYP 862 H+ + F P NP + H Q + P P P P + S+ Sbjct: 1598 TVPGHHVTPGHFLP--SQNPTI-----HHQTAAAVVPPPPPPPPAPGPHLVQQP--NSHQ 1648 Query: 863 HHATQLHAHQPQPATTPTGSQPQSQHAA---------PSPVQHQAGQAPHLGSGQPQQNL 913 H+ H P A TP GS SQ A P P H PH +G Sbjct: 1649 QHSVA-HVVGPVHAVTP-GSHIHSQTAGHHLPPPPPPPGPAPHHH-PPPHPSTGLQGLQA 1705 Query: 914 YHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHH--QQLPHGFTNMAHVTQAHVQTG 971 H + PP PP P S +S + A+HH Q P F + AH T + Sbjct: 1706 QHQHVVNSAPPP-PPPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQ 1764 Query: 972 ITAAPPPHPGAPHPPQVMLLHPPQSHGGP---PQGAVPQSGVPALSASTPSPYP-YIGHP 1027 T PG H P H P GP PQG + +P +AS P+P + P Sbjct: 1765 ATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQG---PNSIPTPTASGFCPHPGSVALP 1821 Query: 1028 QGEQ-PGQAPGFPG 1040 G Q P QA PG Sbjct: 1822 HGVQGPQQASPVPG 1835 Score = 60.1 bits (144), Expect = 1e-08 Identities = 136/590 (23%), Positives = 205/590 (34%), Gaps = 109/590 (18%) Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASC---PEPPIGSAVPTSSAS 477 T PS S T PP +M P SP S PA P+P S V S A Sbjct: 1335 TNECPSPDTSQNTCKSPP----KMSKPGSPGSVIPAQAHGKIFTKPDPQWDSTVSASEAE 1390 Query: 478 --IPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQN 535 + + + + + + + A K T V+ S+++ + L P L+N Sbjct: 1391 NGVHLKTELQQKQLSNNNQALSKNHPPQTHVRN-SSEQLSQKLPSVPTKLHCPPSPHLEN 1449 Query: 536 EQKRFQLEE------------LRKFGAQFKLQPSSSPENSLDPFPPR-----ILKEEPKG 578 K ++ G+ ++ S SP+ P+ + P Sbjct: 1450 PPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPAN 1509 Query: 579 KEKEVDG-LLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQT---GS 634 ++ G L T P G SS T S +++ S + P PPPP PS + Sbjct: 1510 TQQATSGTLFTQTPSGQ--SSATYSQFNQQ-------SLNSTAPPPPPPPPPSSSYYQNQ 1560 Query: 635 PPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPS 694 P + ++ +G +++Q T PN ++ +TS T PG H TP Sbjct: 1561 QPSANFQNYNQLKGSLSQQT-VFTSGPNQ----------ALPGTTSQQTVPG--HHVTPG 1607 Query: 695 IPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVS---NSVPGQQGKYRGAK--G 749 L + ++ + +P P P + P S +SV G Sbjct: 1608 -HFLPSQNPTIHHQTAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGS 1666 Query: 750 SLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYP 809 + Q + H P PP GP P+ P+ G A Q + + Sbjct: 1667 HIHSQTAGHHLPPPPPP-------PGP-----APHHHPPPHPSTGLQGLQAQHQHVVNSA 1714 Query: 810 SQPVFAPMLQSNPRMLTSGSHPQAIVS------SSTPQYPSAEQPT--PQALYATVHQSY 861 P P S +L SG H + + P +PS+ PT P AT H + Sbjct: 1715 PPPPPPPPPSS---VLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHHTTL 1771 Query: 862 ----PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPG 917 H + H P P T P QPQ ++ P+P +G PH GS Sbjct: 1772 GPGPQHQPSGTGPHCPLPVTGP-HLQPQGPNSIPTPT--ASGFCPHPGS----------- 1817 Query: 918 ALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAH 967 +LP G Q PQ + P P + IH Q+P F N H + H Sbjct: 1818 ------VALPHG--VQGPQQASPVPGQI-PIHRAQVPPTFQNNYHGSGWH 1858 Score = 40.0 bits (92), Expect = 0.012 Identities = 37/151 (24%), Positives = 54/151 (35%), Gaps = 17/151 (11%) Query: 340 PSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEAR 399 PS G + Q + P G S P + P + HH ++ GPG + + Sbjct: 1723 PSSVLASGHHTTSAQALHHPPHQGPPLFPS-SAHPTVPPYPSQATHH---TTLGPGPQHQ 1778 Query: 400 GINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPIS 459 PS P P+ G P +P G S+P P A G + P A P + Sbjct: 1779 -----PSGTGPHCPLPVTG------PHLQPQGPNSIPTPTASG--FCPHPGSVALPHGVQ 1825 Query: 460 ASCPEPPIGSAVPTSSASIPVTSSVSDPGVG 490 P+ +P A +P T + G G Sbjct: 1826 GPQQASPVPGQIPIHRAQVPPTFQNNYHGSG 1856 >gi|112734870 hypothetical protein LOC57648 [Homo sapiens] Length = 1094 Score = 72.0 bits (175), Expect = 3e-12 Identities = 167/711 (23%), Positives = 236/711 (33%), Gaps = 113/711 (15%) Query: 305 SSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGPRGGV 364 SSPQ R R + D + + + GS S + + + V P+GG Sbjct: 400 SSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGG- 458 Query: 365 RCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSS 424 S RG G S+ +S + G G S K +RP + S Sbjct: 459 ---SGRGSPSGGSTA---------EASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHS 506 Query: 425 PSNR----PSGETSVPPPPAVGRMYPPRSPK----SAAPAPISASCPEPPIGSAVPTSSA 476 R P G +PP P R P+ P+ + +A CP P S VP S Sbjct: 507 LHQRGLAVPDGPLGLPPKPE--RKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLS- 563 Query: 477 SIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNE 536 PG P SP+ +L+P+ + P TL P+ LA PG Sbjct: 564 ----------PGGSRRPPRSPERTLSPSSGYSSQSGTP--TLPPKGLAGPPAS-PGKAQP 610 Query: 537 QKRFQLEELRKFGAQFKLQPSSSPENSLDPFP-----PRIL------------------- 572 K ++ LR GA +S +S DP P P+IL Sbjct: 611 PKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPF 670 Query: 573 ---KEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKP-----PLAPSGGTEGPEQP 624 +P+ L + PVS+ T++ P PL S + P Sbjct: 671 SPPPSKPRSPNPAAPALAAPAVVPGPVST-TDASPQSPPTPQTTLTPLQESPVISKDQSP 729 Query: 625 PPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTL-NPNAKEFNPTKPLLSVNKSTSTPT 683 PP P PP K E E P A + + L +PN + P P + S Sbjct: 730 PPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPN---WPPPPPPAPEEQDLSMAD 786 Query: 684 SPGPRTHSTPSIPVLTAGQSGLYSPQYIS---------YIPQIHMGPAVQAPQMYPYPV- 733 P P AG SG SP+ +S QI + P P P Sbjct: 787 FPPPEEAFFSVASPEPAGPSG--SPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAP 844 Query: 734 SNSVPGQQGKYRG------AKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSY 787 ++S PG K +KG PP R D P P ++Q P + Sbjct: 845 ASSAPGHVAKLPQKEPVGCSKGGGPP-REDVGAPLVTPSLLQMVRLRSVGAPGGAPTPAL 903 Query: 788 IPYNPQQFPGQPAMMQPMAHYPSQPVFAPM--LQSNPRMLTSGSHPQAIVSSSTPQ-YPS 844 P PQ+ P + A+ + PV AP L + R+ +SS+ P P Sbjct: 904 GPSAPQK-PLRRALSG-----RASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPE 957 Query: 845 AEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHL 904 AE PQ+ +T + + +L +P T Q S + + QAP Sbjct: 958 AEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKK 1017 Query: 905 GSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPH 955 P P G PP P S+P+ + A LPH Sbjct: 1018 SPKAPPPVARKPS--VGVPPPASP---------SYPRAEPLTAPPTNGLPH 1057 Score = 53.9 bits (128), Expect = 8e-07 Identities = 155/651 (23%), Positives = 212/651 (32%), Gaps = 138/651 (21%) Query: 467 IGSAVPTSSASIPVTSSVSDPGV----GSISPASPKISLAPTDVKELSTKEPGRTLEPQE 522 +G + T + + S++ PG+ G P SP +S++P LS P L P Sbjct: 306 VGRSTGTRAPPLTRPMSLAVPGLTGGAGPAEPLSPAMSISP-QATYLSKLIPHAVLPPTV 364 Query: 523 LARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKE 582 G+ LR S + SL F + +P+ + Sbjct: 365 DVVALGRC-------------SLRTLSRCSLHSASPASVRSLGRFSS-VSSPQPRSRHPS 410 Query: 583 VDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEG-PEQ--------PPPPCPSQTG 633 +S S S VSD L+ GG+EG PE PPP S G Sbjct: 411 -----SSSDTWSHSQSSDTIVSDGST---LSSKGGSEGQPESSTASNSVVPPPQGGSGRG 462 Query: 634 SPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTP 693 SP G AE ++ + + + L + + P P RTHS Sbjct: 463 SP----------SGGSTAEASDTLSIRSSGQLSGRSVSLRKLKR----PPPPPRRTHSLH 508 Query: 694 SIPVLTA-GQSGLYSPQYISYIPQIHMGPAVQ------APQMYPYPVSNSVPGQQGKYRG 746 + G GL PQ+ P A P P ++ VPG Sbjct: 509 QRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLS----- 563 Query: 747 AKGSLPPQRSDQ--------HQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQF--- 795 GS P RS + + S P + AGPP A+P + P P++ Sbjct: 564 PGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPP---ASPGKAQPP-KPERVTSL 619 Query: 796 --PGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTS-------GSHPQAIVS-SSTPQYPSA 845 PG + S AP +S P++LT HP+ S P P + Sbjct: 620 RSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRS 679 Query: 846 EQPTPQALYATV------------HQSYPHHATQLHAHQPQPATT----PTGSQPQSQHA 889 P AL A QS P T L Q P + P S P S H Sbjct: 680 PNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHP 739 Query: 890 APSPVQHQ--AGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQS-PQSSFPQPAAVY 946 P P + +AP S ++ L P PP PP P Q + FP P + Sbjct: 740 PPPPTKKPEVVVEAPS-ASETAEEPLQDPN----WPPPPPPAPEEQDLSMADFPPPEEAF 794 Query: 947 AIHHQQLPHG-----------FTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHP-- 993 P G + + T +Q + PPP P AP P H Sbjct: 795 FSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAK 854 Query: 994 -PQSH-------GGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAP 1036 PQ GGPP+ V G P + TPS + PG AP Sbjct: 855 LPQKEPVGCSKGGGPPREDV---GAPLV---TPSLLQMVRLRSVGAPGGAP 899 Score = 38.9 bits (89), Expect = 0.026 Identities = 32/116 (27%), Positives = 46/116 (39%), Gaps = 10/116 (8%) Query: 5 QPLQQPSQPQQPPPTQQ----AVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 +PLQ P+ P PPP + ++A PP + + P P S + P +SP Sbjct: 762 EPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGS---PELVSSPAAS 818 Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSAR---GQSTGKGPPQSPV 113 +A ++ P PP P PG A + G S G GPP+ V Sbjct: 819 SSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDV 874 Score = 35.0 bits (79), Expect = 0.38 Identities = 31/117 (26%), Positives = 43/117 (36%), Gaps = 10/117 (8%) Query: 3 KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPG--PLATSAAPPGPPAAASPCLG 60 KP+ QQP P+ P A P +P N +PG P + P P SP G Sbjct: 524 KPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSG 583 Query: 61 PVAAAGS------GLRRGAEGILAPQPPPPQQ--HQERPGAAAIGSARGQSTGKGPP 109 + +G+ GL QPP P++ PGA+ S + P Sbjct: 584 YSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDP 640 Score = 32.7 bits (73), Expect = 1.9 Identities = 31/114 (27%), Positives = 42/114 (36%), Gaps = 17/114 (14%) Query: 10 PSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAA----PPGPPAAASPCL-GPVAA 64 PS+P+ P P A+A +PGP++T+ A PP P +P PV + Sbjct: 674 PSKPRSPNPAAPALAAPAV---------VPGPVSTTDASPQSPPTPQTTLTPLQESPVIS 724 Query: 65 AGSGLRRGAEGILAPQPPP---PQQHQERPGAAAIGSARGQSTGKGPPQSPVFE 115 P PPP P+ E P A+ Q PP P E Sbjct: 725 KDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPE 778 Score = 30.8 bits (68), Expect = 7.2 Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 5/80 (6%) Query: 33 PPNGGLPGPLATSAAPPGPPAAASPCL-GPVAAAGSGLRRGAEGILAPQPPPPQQHQERP 91 PP+ +P P + + P P A+P L P G A +PQ PP Q P Sbjct: 661 PPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDA----SPQSPPTPQTTLTP 716 Query: 92 GAAAIGSARGQSTGKGPPQS 111 + ++ QS PP S Sbjct: 717 LQESPVISKDQSPPPSPPPS 736 >gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo sapiens] Length = 1636 Score = 71.6 bits (174), Expect = 4e-12 Identities = 105/374 (28%), Positives = 131/374 (35%), Gaps = 61/374 (16%) Query: 683 TSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQG 742 T PGP S P P +G + L P+ P H P P +YP P G Sbjct: 780 TGPGPHYLSGPLPPGTYSGPTQLIQPR----APGPHAMPVAPGPALYPAPAYTPELG--- 832 Query: 743 KYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGP-PLVAATPYSSYIPYNPQQFPG-QPA 800 L P+ S QH S+P + GP P VA P + P QF G + A Sbjct: 833 --------LVPRSSPQHGVVSSPYV-----GVGPAPPVAGLPSAP-----PPQFSGPELA 874 Query: 801 MMQPMAHYPSQPVFAPM-LQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQ 859 M A + AP+ + PR + + P PQ PTP A Q Sbjct: 875 MAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQ----PLPTPYTYPAGAKQ 930 Query: 860 SYP---HHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHP 916 P H ++ + A P P P QPQ H P P Q Q P +L+ P Sbjct: 931 PIPAQHHFSSGIPAGFPAPRIGP---QPQP-HPQPHPSQAFGPQPPQQPLPLQHPHLFPP 986 Query: 917 GALTGTPPSLPPGPSAQSPQSSFPQPAAVYA----IHHQQLPHGFTNMAHVTQAHVQTGI 972 A P LPP QSP PQP + +H Q P Q + Sbjct: 987 QA----PGLLPP----QSPYPYAPQPGVLGQPPPPLHTQLYPGP-------AQDPLPAHS 1031 Query: 973 TAAPPPHPGA---PHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQG 1029 A P P PG PHPP P GP + G + STPSP+ Sbjct: 1032 GALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPS 1091 Query: 1030 EQPGQAPGFPGGAD 1043 PG P P A+ Sbjct: 1092 PGPGPVPPRPPAAE 1105 Score = 56.6 bits (135), Expect = 1e-07 Identities = 93/372 (25%), Positives = 122/372 (32%), Gaps = 75/372 (20%) Query: 610 PPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNP- 668 P PS GP P P T S P LI + + GP A V A + P Sbjct: 773 PSPFPSSTGPGPHYLSGPLPPGTYSGPTQLI--QPRAPGPHAMPVAPGPALYPAPAYTPE 830 Query: 669 ------TKPLLSVNKSTSTPTSPGPRTHSTPSIPV--------------LTAGQSGLYSP 708 + P V S P P PS P T + +P Sbjct: 831 LGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAP 890 Query: 709 QYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMM 768 P+ + PA P +P P +P GAK +P Q H +S P Sbjct: 891 IPSHTAPRPNPTPA-PPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQ----HHFSSGIPAG 945 Query: 769 QAAAAAGP---PLVAATPYSSYIPYNPQQ---------FPGQ-PAMMQPMAHYPSQPVFA 815 A GP P P ++ P PQQ FP Q P ++ P + YP P Sbjct: 946 FPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPG 1005 Query: 816 PMLQSNPRMLTS-----GSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHA 870 + Q P + T P S + P +PS P P PH A Sbjct: 1006 VLGQPPPPLHTQLYPGPAQDPLPAHSGALP-FPSPGPPQP-----------PHPPL---A 1050 Query: 871 HQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGP 930 + P P+T P G Q AAP ++ G Q+ P + PS PGP Sbjct: 1051 YGPAPSTRPMGPQ-----AAPLTIR---------GPSSAGQSTPSPHLVPSPAPSPGPGP 1096 Query: 931 SAQSPQSSFPQP 942 P ++ P P Sbjct: 1097 VPPRPPAAEPPP 1108 Score = 44.3 bits (103), Expect = 6e-04 Identities = 113/459 (24%), Positives = 150/459 (32%), Gaps = 118/459 (25%) Query: 374 PGLSSLPPRGPHHLDNSSP--------------GPGSEARGINGGPSRMSPKAQRPLRGA 419 P SS P GPH+L P PG A + GP+ A P G Sbjct: 775 PFPSSTGP-GPHYLSGPLPPGTYSGPTQLIQPRAPGPHAMPVAPGPALYPAPAYTPELGL 833 Query: 420 KTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE--PPIGSAVPTSSAS 477 SSP + V P VG PAP A P PP S + A Sbjct: 834 VPRSSPQH------GVVSSPYVG----------VGPAPPVAGLPSAPPPQFSGPELAMAV 877 Query: 478 IPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQ 537 P T++V S +P+ + P P + L K P Q Sbjct: 878 RPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQP--IPAQ 935 Query: 538 KRFQLE-----ELRKFGAQFKLQPSSSPENSLDPFPPR--ILKEEPKGKEKEVDGLLTSE 590 F + G Q + P P + P PP+ + + P + GLL Sbjct: 936 HHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLL--- 992 Query: 591 PMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPV 650 P SP P AP G G QPPPP +Q L G +D P Sbjct: 993 PPQSPY--------------PYAPQPGVLG--QPPPPLHTQ-------LYPGPAQDPLPA 1029 Query: 651 AEQVKKSTLNPNAKEFNPTKPLLSVNKSTST-PTSP--GPRTHSTPSIPVLTAGQSGLYS 707 P+ P P L+ + ST P P P T PS +AGQS Sbjct: 1030 HSGALPF---PSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPS----SAGQS---- 1078 Query: 708 PQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPM 767 +P + P P + P G +PP+ PA+ PP Sbjct: 1079 ---------------TPSPHLVPSPAPSPGP----------GPVPPR-----PPAAEPPP 1108 Query: 768 MQAAAAAGPPLVAATPYSSYIPYNPQQFP--GQPAMMQP 804 AA L++++P S + Q P GQP ++QP Sbjct: 1109 CLRRGAAAADLLSSSPESQ---HGGTQSPGGGQP-LLQP 1143 Score = 42.4 bits (98), Expect = 0.002 Identities = 30/86 (34%), Positives = 37/86 (43%), Gaps = 18/86 (20%) Query: 26 RPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQ 85 RPPGG P LPGP A PPG P A+ P P+ ++ + +P P PQ Sbjct: 1508 RPPGGLESPVASLPGP----AEPPGLPPASLPESTPIPSS------SPPPLSSPLPEAPQ 1557 Query: 86 QHQERPGAAAIGSARGQSTGKGPPQS 111 +E P A S GPP S Sbjct: 1558 PKEEPPVPEAPSS--------GPPSS 1575 Score = 38.1 bits (87), Expect = 0.045 Identities = 117/500 (23%), Positives = 163/500 (32%), Gaps = 91/500 (18%) Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464 P +PK P R + P S+PP G PR P+ Sbjct: 718 PRPTAPKPLLPRREESEAVEAGDPPEELRSLPPDMVAG----PR-------------LPD 760 Query: 465 PPIGSAVPTSSASIPVTSSVSDPGVGSIS-PASPKISLAPTDVKELSTKEPGRTLEPQEL 523 +GSA P P SS + PG +S P P PT + + + PG P Sbjct: 761 TFLGSATPLHFPPSPFPSS-TGPGPHYLSGPLPPGTYSGPTQL--IQPRAPGPHAMP--- 814 Query: 524 ARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEV 583 PG L + + L P SSP++ + P G V Sbjct: 815 -----VAPGP-------ALYPAPAYTPELGLVPRSSPQHGVVSSP-----YVGVGPAPPV 857 Query: 584 DGLLTSEP-------MGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPC----PSQT 632 GL ++ P + V T +V + P + PPPPC P Q Sbjct: 858 AGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQP 917 Query: 633 GSPPVGLIKGEDKDEGPVAEQVKKSTLNP---NAKEFNP-----TKPLLSVNKSTSTPTS 684 P G + P+ Q S+ P A P +P S P Sbjct: 918 LPTPYTYPAGAKQ---PIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQ 974 Query: 685 PGPRTHSTPSIPVLTAGQS-GLYSPQY-ISYIPQ---IHMGPAVQAPQMYPYPVSNSVPG 739 P P H P L Q+ GL PQ Y PQ + P Q+YP P + +P Sbjct: 975 PLPLQH-----PHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPA 1029 Query: 740 QQG--KYRGAKGSLPPQRSDQHQPA-SAPPMMQAAA---AAGPPLVAATPYSSYIPYNPQ 793 G + PP + PA S PM AA GP + S ++ +P Sbjct: 1030 HSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPA 1089 Query: 794 QFPG------QPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHP----QAIVSSSTPQYP 843 PG +P +P A +L S+P G+ Q ++ + + Sbjct: 1090 PSPGPGPVPPRPPAAEPPPCLRRGAAAADLLSSSPESQHGGTQSPGGGQPLLQPT--KVD 1147 Query: 844 SAEQPTPQALYATVHQSYPH 863 +AE PQAL Y H Sbjct: 1148 AAEGRRPQALRLIERDPYEH 1167 Score = 36.2 bits (82), Expect = 0.17 Identities = 38/132 (28%), Positives = 43/132 (32%), Gaps = 28/132 (21%) Query: 4 PQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGG-----LPGPLATSAAPPGPPAAASPC 58 P P P+ +QP P Q + P G P G P P + A P PP P Sbjct: 919 PTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPL 978 Query: 59 LGPVAAAGSGLRRGAEGILAP--------------QPPPPQQHQERPGAA----AIGSAR 100 P A G+L P QPPPP Q PG A S Sbjct: 979 QHPHLFPPQ-----APGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGA 1033 Query: 101 GQSTGKGPPQSP 112 GPPQ P Sbjct: 1034 LPFPSPGPPQPP 1045 Score = 36.2 bits (82), Expect = 0.17 Identities = 38/121 (31%), Positives = 44/121 (36%), Gaps = 19/121 (15%) Query: 3 KPQPLQQPSQ------PQQPPPTQ-------QAVARRPPGGTSP-PNGGLPGPLATSAAP 48 +P P PSQ PQQP P Q QA PP SP P PG L P Sbjct: 956 QPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPP--QSPYPYAPQPGVLGQPPPP 1013 Query: 49 PGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPP-PPQQHQERPGAAAIGSARGQSTGKG 107 P P+ A L + G PQPP PP + P +G T +G Sbjct: 1014 LHTQLYPGPAQDPLPAHSGALPFPSPG--PPQPPHPPLAYGPAPSTRPMGPQAAPLTIRG 1071 Query: 108 P 108 P Sbjct: 1072 P 1072 Score = 35.8 bits (81), Expect = 0.22 Identities = 51/201 (25%), Positives = 73/201 (36%), Gaps = 29/201 (14%) Query: 351 PLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSP 410 PL ++ GP + S G P S PP+ PH P P + G P + Sbjct: 1013 PLHTQLYPGPAQDPLPAHS-GALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTI-- 1069 Query: 411 KAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSA 470 + P ++ SP PS S P P PPR P + EPP Sbjct: 1070 --RGPSSAGQSTPSPHLVPSPAPSPGPGPV-----PPRPPAA-----------EPPPCLR 1111 Query: 471 VPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKV 530 ++A + +S S G G+ SP + L PT V + P + R+ + Sbjct: 1112 RGAAAADLLSSSPESQHG-GTQSPGGGQPLLQPTKVDAAEGRRP-------QALRLIERD 1163 Query: 531 PGLQNEQKRFQLEELRKFGAQ 551 P E+ R +EL F Q Sbjct: 1164 PYEHPERLRQLQQELEAFRGQ 1184 Score = 32.3 bits (72), Expect = 2.5 Identities = 28/94 (29%), Positives = 30/94 (31%), Gaps = 10/94 (10%) Query: 4 PQPLQQPSQPQQPPPTQ-QAVARRPPG---------GTSPPNGGLPGPLATSAAPPGPPA 53 P P P QP PP A + RP G G S P P + P P Sbjct: 1035 PFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGP 1094 Query: 54 AASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQH 87 P P A LRRGA P QH Sbjct: 1095 GPVPPRPPAAEPPPCLRRGAAAADLLSSSPESQH 1128 Score = 32.0 bits (71), Expect = 3.2 Identities = 37/148 (25%), Positives = 57/148 (38%), Gaps = 21/148 (14%) Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAP--APISASCPEPPIGSAVPTSSASI 478 T++ S RP G P G PP P ++ P PI +S P PP+ S +P + Sbjct: 1501 TIAKLSIRPPGGLESPVASLPGPAEPPGLPPASLPESTPIPSSSP-PPLSSPLPEAPQ-- 1557 Query: 479 PVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQK 538 P + AP+ S+ E +L P+ + + + G Q K Sbjct: 1558 --------------PKEEPPVPEAPSSGPPSSSLELLASLTPEAFS-LDSSLRGKQRMSK 1602 Query: 539 RFQLEELRKFGAQFKLQPSSSPENSLDP 566 L+ G + +PS P + LDP Sbjct: 1603 HNFLQAHNGQGLR-ATRPSDDPLSLLDP 1629 Score = 32.0 bits (71), Expect = 3.2 Identities = 30/110 (27%), Positives = 42/110 (38%), Gaps = 25/110 (22%) Query: 927 PPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPP 986 PPG +SP +S P PA + LP T I ++ PP +P P Sbjct: 1509 PPG-GLESPVASLPGPAEPPGLPPASLPES-------------TPIPSSSPPPLSSPLP- 1553 Query: 987 QVMLLHPPQSHGGPPQGAVPQSGVPA-----LSASTPSPYPYIGHPQGEQ 1031 PQ PP P SG P+ L++ TP + +G+Q Sbjct: 1554 -----EAPQPKEEPPVPEAPSSGPPSSSLELLASLTPEAFSLDSSLRGKQ 1598 Score = 31.2 bits (69), Expect = 5.5 Identities = 26/84 (30%), Positives = 34/84 (40%), Gaps = 4/84 (4%) Query: 560 PENSLDPFPPRILKEEPKGKEKEVDGLL-TSEPMGSPVSSKTESVSDKEDKPPLAPSGGT 618 P +S+ ++ P G E V L +EP G P +S ES PP S Sbjct: 1494 PISSIQATIAKLSIRPPGGLESPVASLPGPAEPPGLPPASLPESTPIPSSSPPPLSSPLP 1553 Query: 619 EGP---EQPPPPCPSQTGSPPVGL 639 E P E+PP P +G P L Sbjct: 1554 EAPQPKEEPPVPEAPSSGPPSSSL 1577 Score = 30.8 bits (68), Expect = 7.2 Identities = 30/111 (27%), Positives = 36/111 (32%), Gaps = 5/111 (4%) Query: 7 LQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAG 66 +Q P P A PP PP LP P A P A + A Sbjct: 887 IQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGF 946 Query: 67 SGLRRGAEGILAPQPPPPQQHQERPGAAAIGSAR-----GQSTGKGPPQSP 112 R G + PQP P Q +P + Q+ G PPQSP Sbjct: 947 PAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSP 997 >gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 [Homo sapiens] Length = 2231 Score = 71.6 bits (174), Expect = 4e-12 Identities = 133/524 (25%), Positives = 182/524 (34%), Gaps = 108/524 (20%) Query: 574 EEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG 633 + P G ++ LLTS SP+ ++ S E P AP P+ + G Sbjct: 352 QHPSGATPTLNQLLTSP---SPMM-RSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407 Query: 634 SPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGP---RTH 690 G KD G A+ S A++ + P +S P +PGP R+ Sbjct: 408 GQQAAAGMGLGKDMG--AQYAAASPAWAAAQQ--RSHPAMS-------PGTPGPTMGRSQ 456 Query: 691 STPSIPVLTA-------GQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK 743 +P P++ G + PQ S P GP PQ YP + PG Sbjct: 457 GSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPP--GPQRYPIGIQGRTPGAMAG 514 Query: 744 YRGAKGSLPPQR-----------------SDQHQPASAPPMMQAAAAAGPPLVAATPYSS 786 + + +PPQ S Q QP PP Q Sbjct: 515 MQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQ----------------- 557 Query: 787 YIPYNPQQ-FPGQPAMMQPMAHYPSQPVFAPMLQSNPRM-LTSGSHPQAIVSSSTPQYPS 844 Y+P QQ + Q M Q SQP AP ++ + L P SS P Sbjct: 558 YLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERP-----SSLPDLSG 612 Query: 845 AEQPTPQALYATVHQSY-PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPH 903 + P AT+ + +T Q PA +P S HA+P G +P Sbjct: 613 SIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPF-----SPHASPHLSSIPGGPSPS 667 Query: 904 -----LGSGQPQQNLYHPGALTGTP-PSLPPGPSAQSPQSSFPQPAAVYAIHHQQLP--H 955 +GS Q + P ++ G+ P PPG +QS SS P A+ +P Sbjct: 668 PVGSPVGSNQSRSGPISPASIPGSQMPPQPPG--SQSESSSHP------ALSQSPMPQER 719 Query: 956 GF-----TNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHG--GP------PQ 1002 GF N QTG + +P P PG + S G GP PQ Sbjct: 720 GFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQ 779 Query: 1003 GAVPQ----SGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGA 1042 G + SGVP+ S S P P I + GQ P P GA Sbjct: 780 GNYSRPPAYSGVPSASYSGPGPGMGIS-ANNQMHGQGPSQPCGA 822 Score = 62.4 bits (150), Expect = 2e-09 Identities = 156/758 (20%), Positives = 246/758 (32%), Gaps = 143/758 (18%) Query: 321 RTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLP 380 R +E +AV + + S SR+G + + Q G+ SSS +P +S Sbjct: 869 RKAQEAAAAVMQAAAN----SAQSRQGSFPGMNQ-------SGLMASSSPYSQPMNNS-- 915 Query: 381 PRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA 440 L N+ P S A + + A G L P E P P + Sbjct: 916 ----SSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPES 971 Query: 441 VGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKIS 500 + S P P + P P S+ SS + S+S PG +P+SPK S Sbjct: 972 KSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDESDSISSPGWPK-TPSSPKSS 1030 Query: 501 LAPTDVKELST-----KEPGRTL------------------------EPQELARI---AG 528 + T ++++ EP R L +P +L R+ Sbjct: 1031 SSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVK 1090 Query: 529 KVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLT 588 ++ GL K ++ R+ + SSS +SL K++ + L Sbjct: 1091 EIGGLAQVNKN---KKWRELATNLNVGTSSSAASSL--------------KKQYIQYLFA 1133 Query: 589 SE---PMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDK 645 E G + S D + +P L P P P TGS + + G+ K Sbjct: 1134 FECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLK 1193 Query: 646 DEGPVA---------EQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSI- 695 P + + + ST++ + F+ +++ TP +P + S P + Sbjct: 1194 PPTPASTPHGQMTPMQGGRSSTISVH-DPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVM 1252 Query: 696 -----------------------PVLTAGQ------SGLYSPQYISYIPQIHMGPAVQAP 726 P +T GQ +Y+ + + MG Q P Sbjct: 1253 GRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFP 1312 Query: 727 QMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPM----MQAAAAAGPPL---- 778 Y + GQQ +G PP HQP P GPP Sbjct: 1313 YGASYDRRHEPYGQQYPGQGPPSGQPPYGG--HQPGLYPQQPNYKRHMDGMYGPPAKRHE 1370 Query: 779 --VAATPYSSYIPYNPQQFPGQ---PAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQA 833 + YSS Q+ G P YP P +Q ++ T G PQ Sbjct: 1371 GDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYP-YPYSRERMQGPGQIQTHGIPPQ- 1428 Query: 834 IVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSP 893 + Q S+E P A YP+ Q Q P ++ Sbjct: 1429 -MMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQR 1487 Query: 894 VQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQ------SSFPQPAAVY- 946 + H++ H+ QP Y + + P + PP PS Q+P S P PA+ Sbjct: 1488 INHESQWPSHVSQRQP----YMSSSASMQPITRPPQPSYQTPPSLPNHISRAPSPASFQR 1543 Query: 947 AIHHQQLPHGFTNMAHVTQAHVQ----TGITAAPPPHP 980 ++ ++ P + + V T PPP P Sbjct: 1544 SLENRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQP 1581 Score = 54.3 bits (129), Expect = 6e-07 Identities = 155/707 (21%), Positives = 229/707 (32%), Gaps = 111/707 (15%) Query: 374 PG-LSSLPPRGPHHLDNSSPGPGSEARGIN----------------GGPSRMSPKAQRPL 416 PG +SS+ P P PG G +N SR Sbjct: 839 PGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQ 898 Query: 417 RGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSA 476 G SSP ++P +S M P S APA +++S + + + Sbjct: 899 SGLMASSSPYSQPMNNSS-------SLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGES 951 Query: 477 SIPVTSSVSDPGVGSISPASP-KISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQN 535 +P+ G+ P S K S + + + T PG P ++ + + Sbjct: 952 KLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPT--PGNLPVPSPMSPSSASISSFHG 1009 Query: 536 EQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKE----VDGLLT-SE 590 ++ + + G + PSS +S +I K G E E VD LT E Sbjct: 1010 DES----DSISSPG--WPKTPSSPKSSSSTTTGEKITKVYELGNEPERKLWVDRYLTFME 1063 Query: 591 PMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIK-GEDKDEGP 649 GSPVSS D L C + G GL + ++K Sbjct: 1064 ERGSPVSSLPAVGKKPLDLFRLYV-------------CVKEIG----GLAQVNKNKKWRE 1106 Query: 650 VAEQVKKSTLNPNAKEFNPT--KPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYS 707 +A + T + A + L + P P ST T Q L Sbjct: 1107 LATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGD----TKKQPKLQP 1162 Query: 708 PQYISYIPQIHMGPAVQAPQMYPYPVSNS---VPGQQGKYRGAK---GSLPPQRSDQHQP 761 P + ++Q PQ SNS VPG A G + P + + Sbjct: 1163 PSPAN-------SGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSST 1215 Query: 762 ASA-PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQ- 819 S P + ++ P + TP + Y QQ P +M M + P++ F M + Sbjct: 1216 ISVHDPFSDVSDSSFPKRNSMTPNAPY-----QQGMSMPDVMGRMPYEPNKDPFGGMRKV 1270 Query: 820 --SNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPAT 877 S+ +T G P + + Q PS L Q +P+ A+ H+P Sbjct: 1271 PGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSN---LGMGQRQQFPYGASYDRRHEPYGQQ 1327 Query: 878 TPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQS 937 P P Q P HQ G P QP + G GP A+ + Sbjct: 1328 YPGQGPPSGQ---PPYGGHQPGLYPQ----QPNYKRHMDGMY---------GPPAKRHEG 1371 Query: 938 SFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLH-PPQS 996 Y+ Q++ + + G P P Q+ PPQ Sbjct: 1372 DMYNMQ--YSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQM 1429 Query: 997 HGGPPQGAV---PQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPG 1040 GGP Q + PQ + A A PYPY P QAP +PG Sbjct: 1430 MGGPLQSSSSEGPQQNMWA--ARNDMPYPYQNRQGPGGPTQAPPYPG 1474 Score = 40.8 bits (94), Expect = 0.007 Identities = 138/618 (22%), Positives = 188/618 (30%), Gaps = 155/618 (25%) Query: 533 LQNEQKRFQLEELRKFGAQFKLQPSSSP---ENSLD------PFPPRILKEEPKGKEKEV 583 LQ + +FQ ++ ++ Q + Q P NSL P P +++ G K+ Sbjct: 48 LQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDS 107 Query: 584 DGLLTSEPMGSPVSSKTESVSDKEDKPPLA----------PSGGTEGPEQPPPPCPSQTG 633 ++P G P+ SK D++D PP P G G +QPP P G Sbjct: 108 AAGGQADPPGPPLLSKP---GDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGG 164 Query: 634 SPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTP 693 GP A EFN ++ P S GP + P Sbjct: 165 --------------GPAA-----------VPEFNNYY-------GSAAPASGGPGGRAGP 192 Query: 694 SIPV----LTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQ-------- 741 + G ++S + M P + + YP N PG Sbjct: 193 CFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGG 252 Query: 742 -------GKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSY---IPYN 791 G G G A A AAAAAG SS + + Sbjct: 253 GGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSS 312 Query: 792 PQQFPGQPAMMQPM---AHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQP 848 P+Q G MM P A S+ R HP S +TP Sbjct: 313 PRQ-QGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHP----SGATPTLNQL-LT 366 Query: 849 TPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQ 908 +P + + SYP +++ A P SQPQSQ AA A +G G+ Sbjct: 367 SPSPMMRSYGGSYPEYSSP-------SAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGK 419 Query: 909 PQ--------------QNLYHPGALTGTP-PSL------PPGPSA--------------Q 933 Q HP GTP P++ P P Sbjct: 420 DMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHS 479 Query: 934 SPQSSFPQPAAVYA-IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPH------------- 979 PQ S P P Y Q+ P G A +Q PP + Sbjct: 480 QPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQ 539 Query: 980 -------PGAPH-PPQVMLLHPPQSHGGPPQGAVPQSGV-----PALSASTPSPYPYIGH 1026 P PH PPQ L PQ + Q G P L+ P+ + + Sbjct: 540 QPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPN-HEDLNL 598 Query: 1027 PQGEQPGQAPGFPGGADD 1044 Q E+P P G DD Sbjct: 599 IQQERPSSLPDLSGSIDD 616 Score = 32.7 bits (73), Expect = 1.9 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 8/80 (10%) Query: 380 PPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPP- 438 PP P+H+ + P P S R + +RMSP L K P+ + + PPP Sbjct: 1525 PPSLPNHISRA-PSPASFQRSLE---NRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQ 1580 Query: 439 -PAVGR--MYPPRSPKSAAP 455 P + R +PP S +++ P Sbjct: 1581 PPPIRREITFPPGSVEASQP 1600 Score = 32.3 bits (72), Expect = 2.5 Identities = 40/135 (29%), Positives = 45/135 (33%), Gaps = 26/135 (19%) Query: 5 QPLQQPSQPQQPPPTQQAVARRPPGGT--------SPPNGGLPGPLATSAA-PPGPPAA- 54 Q QQ Q QQ P + GG P +GG A A PPGPP Sbjct: 63 QQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS 122 Query: 55 -------ASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAI-------GSAR 100 A P +G AG G L Q PP G AA+ GSA Sbjct: 123 KPGDEDDAPPKMG--EPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA 180 Query: 101 GQSTGKGPPQSPVFE 115 S G G P F+ Sbjct: 181 PASGGPGGRAGPCFD 195 Score = 31.6 bits (70), Expect = 4.2 Identities = 31/114 (27%), Positives = 39/114 (34%), Gaps = 9/114 (7%) Query: 9 QPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGP-------PAAASPCLGP 61 Q P PT + P G P + SA PP P AA + G Sbjct: 350 QNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQ 409 Query: 62 VAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK--GPPQSPV 113 AAAG GL + A P Q+R A G + G+ G P P+ Sbjct: 410 QAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPM 463 Score = 30.8 bits (68), Expect = 7.2 Identities = 21/70 (30%), Positives = 29/70 (41%), Gaps = 4/70 (5%) Query: 36 GGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGIL----APQPPPPQQHQERP 91 G G A P+ A+P L + + S + R G +P PPP Q + Sbjct: 338 GSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQS 397 Query: 92 GAAAIGSARG 101 AAA G+A G Sbjct: 398 QAAAAGAAAG 407 >gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 [Homo sapiens] Length = 2178 Score = 71.6 bits (174), Expect = 4e-12 Identities = 133/524 (25%), Positives = 182/524 (34%), Gaps = 108/524 (20%) Query: 574 EEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG 633 + P G ++ LLTS SP+ ++ S E P AP P+ + G Sbjct: 352 QHPSGATPTLNQLLTSP---SPMM-RSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407 Query: 634 SPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGP---RTH 690 G KD G A+ S A++ + P +S P +PGP R+ Sbjct: 408 GQQAAAGMGLGKDMG--AQYAAASPAWAAAQQ--RSHPAMS-------PGTPGPTMGRSQ 456 Query: 691 STPSIPVLTA-------GQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK 743 +P P++ G + PQ S P GP PQ YP + PG Sbjct: 457 GSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPP--GPQRYPIGIQGRTPGAMAG 514 Query: 744 YRGAKGSLPPQR-----------------SDQHQPASAPPMMQAAAAAGPPLVAATPYSS 786 + + +PPQ S Q QP PP Q Sbjct: 515 MQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQ----------------- 557 Query: 787 YIPYNPQQ-FPGQPAMMQPMAHYPSQPVFAPMLQSNPRM-LTSGSHPQAIVSSSTPQYPS 844 Y+P QQ + Q M Q SQP AP ++ + L P SS P Sbjct: 558 YLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERP-----SSLPDLSG 612 Query: 845 AEQPTPQALYATVHQSY-PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPH 903 + P AT+ + +T Q PA +P S HA+P G +P Sbjct: 613 SIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPF-----SPHASPHLSSIPGGPSPS 667 Query: 904 -----LGSGQPQQNLYHPGALTGTP-PSLPPGPSAQSPQSSFPQPAAVYAIHHQQLP--H 955 +GS Q + P ++ G+ P PPG +QS SS P A+ +P Sbjct: 668 PVGSPVGSNQSRSGPISPASIPGSQMPPQPPG--SQSESSSHP------ALSQSPMPQER 719 Query: 956 GF-----TNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHG--GP------PQ 1002 GF N QTG + +P P PG + S G GP PQ Sbjct: 720 GFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQ 779 Query: 1003 GAVPQ----SGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGA 1042 G + SGVP+ S S P P I + GQ P P GA Sbjct: 780 GNYSRPPAYSGVPSASYSGPGPGMGIS-ANNQMHGQGPSQPCGA 822 Score = 54.7 bits (130), Expect = 5e-07 Identities = 166/786 (21%), Positives = 261/786 (33%), Gaps = 155/786 (19%) Query: 331 QRQGSGRESPSLA--------SREGKYIPLPQRVREGPRGGVRCSSSRG----------G 372 Q SG P ++ SR Y +P GP G+ S++ G Sbjct: 762 QSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCG 821 Query: 373 RPGLSSLPPRG----PHHLDNSSPGPGSEARGINGGPSRMSP------KAQRPLRGAKTL 422 L +P G P + SS P S GGP P KAQ A Sbjct: 822 AVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAA-AAVMQ 880 Query: 423 SSPSNRPSGETSVPPPPAVGRMY---PPRSPKSAAPAPISASCPEPPIGSAVPTSSASIP 479 ++ ++ S + S P G M P P + + + ++ P P S A Sbjct: 881 AAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAP--------PYSMAPAM 932 Query: 480 VTSSVSDPGVGSI-SPASPKISLA-PTDVKELSTKEPGRTLEPQELARIAG----KVPGL 533 V SS + G+ + SP K+ L D KE T +P + + G KV L Sbjct: 933 VNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYEL 992 Query: 534 QNE-QKRFQLEELRKFGAQFKLQPSSSP---ENSLDPFPPRILKEEPKG-----KEKEVD 584 NE +++ ++ F + SS P + LD F + +E G K K+ Sbjct: 993 GNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWR 1052 Query: 585 GLLTSEPMGSPVSSKTE--------------SVSDKEDKPP-LAPSGGTEGPEQPPPPCP 629 L T+ +G+ S+ + + E+ PP + +G T+ + PP P Sbjct: 1053 ELATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSP 1112 Query: 630 S------------QTGSPPVGLIKGEDKDEGPVA---------EQVKKSTLNPNAKEFNP 668 + TGS + + G+ K P + + + ST++ + F+ Sbjct: 1113 ANSGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPHGQMTPMQGGRSSTISVH-DPFSD 1171 Query: 669 TKPLLSVNKSTSTPTSPGPRTHSTPSI------------------------PVLTAGQ-- 702 +++ TP +P + S P + P +T GQ Sbjct: 1172 VSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPFGGMRKVPGSSEPFMTQGQMP 1231 Query: 703 ----SGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQ 758 +Y+ + + MG Q P Y + GQQ +G PP Sbjct: 1232 NSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYGQQYPGQGPPSGQPPYGG-- 1289 Query: 759 HQPASAPPM----MQAAAAAGPPL------VAATPYSSYIPYNPQQFPGQ---PAMMQPM 805 HQP P GPP + YSS Q+ G P Sbjct: 1290 HQPGLYPQQPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQ 1349 Query: 806 AHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHA 865 YP P +Q ++ T G PQ + Q S+E P A YP+ Sbjct: 1350 GQYP-YPYSRERMQGPGQIQTHGIPPQ--MMGGPLQSSSSEGPQQNMWAARNDMPYPYQN 1406 Query: 866 TQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPS 925 Q Q P ++ + H++ H+ QP Y + + P + Sbjct: 1407 RQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQP----YMSSSASMQPIT 1462 Query: 926 LPPGPSAQSPQ------SSFPQPAAVY-AIHHQQLPHGFTNMAHVTQAHVQ----TGITA 974 PP PS Q+P S P PA+ ++ ++ P + + V T Sbjct: 1463 RPPQPSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPFLPSMKMQKVMPTVPTSQVT 1522 Query: 975 APPPHP 980 PPP P Sbjct: 1523 GPPPQP 1528 Score = 53.1 bits (126), Expect = 1e-06 Identities = 165/720 (22%), Positives = 239/720 (33%), Gaps = 101/720 (14%) Query: 353 PQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKA 412 PQ + GP+G + G P S P PG G A G P Sbjct: 771 PQMSQYGPQGNYSRPPAYSGVPSASYSGP---------GPGMGISANNQMHGQGPSQPCG 821 Query: 413 QRPLRGAKTLSSPSNRP-SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAV 471 PL G + NRP G S P + G M P P P + + +AV Sbjct: 822 AVPL-GRMPSAGMQNRPFPGNMSSMTPSSPG-MSQQGGPGMGPPMP-TVNRKAQEAAAAV 878 Query: 472 PTSSASIPVTSSVSDPGV---GSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAG 528 ++A+ + S PG+ G ++ +SP ++T+ P ++ P + A Sbjct: 879 MQAAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAPPYSMAPAMVNSSAA 938 Query: 529 KVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN------SLDPFPPRILKEEPKGKEKE 582 V GL + + + A K + + PE+ S +I K G E E Sbjct: 939 SV-GLADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYELGNEPE 997 Query: 583 ----VDGLLT-SEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPV 637 VD LT E GSPVSS D L C + G Sbjct: 998 RKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYV-------------CVKEIG---- 1040 Query: 638 GLIK-GEDKDEGPVAEQVKKSTLNPNAKEFNPT--KPLLSVNKSTSTPTSPGPRTHSTPS 694 GL + ++K +A + T + A + L + P P ST Sbjct: 1041 GLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGD 1100 Query: 695 IPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNS---VPGQQGKYRGAK--- 748 T Q L P + ++Q PQ SNS VPG A Sbjct: 1101 ----TKKQPKLQPPSPAN-------SGSLQGPQTPQSTGSNSMAEVPGDLKPPTPASTPH 1149 Query: 749 GSLPPQRSDQHQPASA-PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAH 807 G + P + + S P + ++ P + TP + Y QQ P +M M + Sbjct: 1150 GQMTPMQGGRSSTISVHDPFSDVSDSSFPKRNSMTPNAPY-----QQGMSMPDVMGRMPY 1204 Query: 808 YPSQPVFAPMLQ---SNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHH 864 P++ F M + S+ +T G P + + Q PS L Q +P+ Sbjct: 1205 EPNKDPFGGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSN---LGMGQRQQFPYG 1261 Query: 865 ATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPP 924 A+ H+P P P Q P HQ G P QP + G Sbjct: 1262 ASYDRRHEPYGQQYPGQGPPSGQ---PPYGGHQPGLYPQ----QPNYKRHMDGMY----- 1309 Query: 925 SLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPH 984 GP A+ + Y+ Q++ + + G P Sbjct: 1310 ----GPPAKRHEGDMYNMQ--YSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRERMQG 1363 Query: 985 PPQVMLLH-PPQSHGGPPQGAV---PQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPG 1040 P Q+ PPQ GGP Q + PQ + A A PYPY P QAP +PG Sbjct: 1364 PGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWA--ARNDMPYPYQNRQGPGGPTQAPPYPG 1421 Score = 40.8 bits (94), Expect = 0.007 Identities = 138/618 (22%), Positives = 188/618 (30%), Gaps = 155/618 (25%) Query: 533 LQNEQKRFQLEELRKFGAQFKLQPSSSP---ENSLD------PFPPRILKEEPKGKEKEV 583 LQ + +FQ ++ ++ Q + Q P NSL P P +++ G K+ Sbjct: 48 LQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDS 107 Query: 584 DGLLTSEPMGSPVSSKTESVSDKEDKPPLA----------PSGGTEGPEQPPPPCPSQTG 633 ++P G P+ SK D++D PP P G G +QPP P G Sbjct: 108 AAGGQADPPGPPLLSKP---GDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGG 164 Query: 634 SPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTP 693 GP A EFN ++ P S GP + P Sbjct: 165 --------------GPAA-----------VPEFNNYY-------GSAAPASGGPGGRAGP 192 Query: 694 SIPV----LTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQ-------- 741 + G ++S + M P + + YP N PG Sbjct: 193 CFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGG 252 Query: 742 -------GKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSY---IPYN 791 G G G A A AAAAAG SS + + Sbjct: 253 GGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSS 312 Query: 792 PQQFPGQPAMMQPM---AHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQP 848 P+Q G MM P A S+ R HP S +TP Sbjct: 313 PRQ-QGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHP----SGATPTLNQL-LT 366 Query: 849 TPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQ 908 +P + + SYP +++ A P SQPQSQ AA A +G G+ Sbjct: 367 SPSPMMRSYGGSYPEYSSP-------SAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGK 419 Query: 909 PQ--------------QNLYHPGALTGTP-PSL------PPGPSA--------------Q 933 Q HP GTP P++ P P Sbjct: 420 DMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHS 479 Query: 934 SPQSSFPQPAAVYA-IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPH------------- 979 PQ S P P Y Q+ P G A +Q PP + Sbjct: 480 QPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQ 539 Query: 980 -------PGAPH-PPQVMLLHPPQSHGGPPQGAVPQSGV-----PALSASTPSPYPYIGH 1026 P PH PPQ L PQ + Q G P L+ P+ + + Sbjct: 540 QPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPN-HEDLNL 598 Query: 1027 PQGEQPGQAPGFPGGADD 1044 Q E+P P G DD Sbjct: 599 IQQERPSSLPDLSGSIDD 616 Score = 32.7 bits (73), Expect = 1.9 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 8/80 (10%) Query: 380 PPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPP- 438 PP P+H+ + P P S R + +RMSP L K P+ + + PPP Sbjct: 1472 PPSLPNHISRA-PSPASFQRSLE---NRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQ 1527 Query: 439 -PAVGR--MYPPRSPKSAAP 455 P + R +PP S +++ P Sbjct: 1528 PPPIRREITFPPGSVEASQP 1547 Score = 32.3 bits (72), Expect = 2.5 Identities = 40/135 (29%), Positives = 45/135 (33%), Gaps = 26/135 (19%) Query: 5 QPLQQPSQPQQPPPTQQAVARRPPGGT--------SPPNGGLPGPLATSAA-PPGPPAA- 54 Q QQ Q QQ P + GG P +GG A A PPGPP Sbjct: 63 QQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS 122 Query: 55 -------ASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAI-------GSAR 100 A P +G AG G L Q PP G AA+ GSA Sbjct: 123 KPGDEDDAPPKMG--EPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA 180 Query: 101 GQSTGKGPPQSPVFE 115 S G G P F+ Sbjct: 181 PASGGPGGRAGPCFD 195 Score = 31.6 bits (70), Expect = 4.2 Identities = 31/114 (27%), Positives = 39/114 (34%), Gaps = 9/114 (7%) Query: 9 QPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGP-------PAAASPCLGP 61 Q P PT + P G P + SA PP P AA + G Sbjct: 350 QNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQ 409 Query: 62 VAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK--GPPQSPV 113 AAAG GL + A P Q+R A G + G+ G P P+ Sbjct: 410 QAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPM 463 Score = 30.8 bits (68), Expect = 7.2 Identities = 21/70 (30%), Positives = 29/70 (41%), Gaps = 4/70 (5%) Query: 36 GGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGIL----APQPPPPQQHQERP 91 G G A P+ A+P L + + S + R G +P PPP Q + Sbjct: 338 GSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQS 397 Query: 92 GAAAIGSARG 101 AAA G+A G Sbjct: 398 QAAAAGAAAG 407 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 70.9 bits (172), Expect = 6e-12 Identities = 128/566 (22%), Positives = 197/566 (34%), Gaps = 71/566 (12%) Query: 394 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRP------SGETSVPPPPAVGRMYPP 447 P +A GP+ +PK P + S+ P S T+ P P Sbjct: 197 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 256 Query: 448 RSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVK 507 +PK AP P P A T+ P T+ + +P +PK APT Sbjct: 257 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPT--- 312 Query: 508 ELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPF 567 + KEP T P+E K P ++ + A K P++ E + Sbjct: 313 --TPKEPAPT-TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA---- 365 Query: 568 PPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP 627 P KE KE EP +P ++K+ + KE AP+ P P P Sbjct: 366 -PTTPKEPAPTTTKEPSPTTPKEP--APTTTKSAPTTTKEP----APTTTKSAPTTPKEP 418 Query: 628 CPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNK--STSTPTSP 685 P+ T P K+ P + T P +P + K + +TP P Sbjct: 419 SPTTTKEP----APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 474 Query: 686 GPRT--HSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK 743 P T + P+ P +P+ ++ P PA P+ ++ + P + Sbjct: 475 APTTPKETAPTTPKKLTPT----TPEKLA--PTTPEKPAPTTPE----ELAPTTPEE--- 521 Query: 744 YRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQ 803 P + +PA P +AAA P A T P P+ +PA Sbjct: 522 ---------PTPTTPEEPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPK----EPAPTT 566 Query: 804 PMAHYPSQPV-FAPMLQSNPRMLT-SGSHPQAIVSSST--PQYPSAEQPTPQALYATVHQ 859 P P+ P AP P T P+ + ++T P + ++P P T Sbjct: 567 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA-P 625 Query: 860 SYPHHATQLHAHQPQPATTPTGSQPQS-QHAAPSPVQHQAGQ--APHLGSGQPQQNLYHP 916 + P +P P TTP G+ P + + AP+ + A + AP G P Sbjct: 626 TTPKEPAPTTPKEPAP-TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 684 Query: 917 GALT--GTPPSLPPGPSAQSPQSSFP 940 T T P+ P P+ +P+ P Sbjct: 685 APTTPKETAPTTPKEPAPTTPKKPAP 710 Score = 67.8 bits (164), Expect = 5e-11 Identities = 124/579 (21%), Positives = 183/579 (31%), Gaps = 72/579 (12%) Query: 419 AKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASI 478 +K L+ P+ P ET+ P + P+ P P +++ P+ P PT+ S Sbjct: 191 SKVLAKPT--PKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEP----TPTTIKSA 240 Query: 479 PVTSSVSDPGVGSISPASPKISLAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQN 535 P T PA APT KE +TKEP T P+E A K P Sbjct: 241 PTTPK---------EPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKEPA--- 287 Query: 536 EQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSP 595 S+P +P P K P KE EP +P Sbjct: 288 -----------------PTTTKSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEP--TP 327 Query: 596 VSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG-SPPVGLIKGEDKDEGPVAEQV 654 + K + + KE P P++P P P + + P K+ P + Sbjct: 328 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 387 Query: 655 KKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYI 714 T +A + + +TP P P T P+ T + +P+ Sbjct: 388 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTTPK--KPA 443 Query: 715 PQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAA 774 P PA P+ P P + P A + P + + P + A Sbjct: 444 PTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTPEKLAPT 501 Query: 775 GPPLVAATPYSSYIPYNPQQ----FPGQPAMMQPMAHYPSQPVF-APMLQSNPRMLTSGS 829 P A T P P++ P +PA P A P+ P AP P T Sbjct: 502 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 561 Query: 830 HPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHA 889 + P P PT T+ + P + + P TT + Sbjct: 562 PAPTTPKETAPTTPKGTAPT------TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 615 Query: 890 APSPVQHQAGQAPHLGSGQPQQNLYHPGALT--GTPPSLPPGPSAQSPQSSFPQPAAVYA 947 AP+ + G AP P T GT P+ P+ +P+ P+ A Sbjct: 616 APTTPK---GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 672 Query: 948 IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPP 986 + P T+ +T T P P P P Sbjct: 673 ---TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP 708 Score = 62.8 bits (151), Expect = 2e-09 Identities = 107/502 (21%), Positives = 162/502 (32%), Gaps = 67/502 (13%) Query: 406 SRMSPKAQRPLRGAKTLSSPSN--RPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCP 463 ++ +P + T S+P+ PS T+ P P + P +PK AP P Sbjct: 393 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 452 Query: 464 EPPIGSAVPTSSASIPVTSSVSDPGV-GSISPASPKISLAPTDVKEL--STKEPGRTLEP 520 P A T+ P T P +P +PK L PT ++L +T E P Sbjct: 453 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTP 511 Query: 521 QELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFP-------PRILK 573 +ELA + P ++ +++P +P P P K Sbjct: 512 EELAPTTPEEPTPTTPEEPAP-----------TTPKAAAPNTPKEPAPTTPKEPAPTTPK 560 Query: 574 EEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG 633 E KE + P G+ ++ E KP T E C Sbjct: 561 EPAPTTPKET---APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 617 Query: 634 SPPVGLIKGEDKDEGPV-----AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPR 688 + P G K+ P A K T KE PT P K + T+ GP Sbjct: 618 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP- 676 Query: 689 THSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAK 748 T +T P T + P PA P+ P P + P Sbjct: 677 TSTTSDKPAPTTPK---------ETAPTTPKEPAPTTPKK-PAPTTPETP---------- 716 Query: 749 GSLPPQRSDQHQPASA--PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMA 806 PP S+ P + P + + P ++A P + +P++ PG P P A Sbjct: 717 ---PPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE-PGVPTTKTPAA 772 Query: 807 HYPSQPVFAP------MLQSNPRMLTSGSHPQAIVSSSTPQYPSAE--QPTPQALYATVH 858 P A L++ P T+ +++T + ++ T Q T Sbjct: 773 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 832 Query: 859 QSYPHHATQLHAHQPQPATTPT 880 + P T L P T T Sbjct: 833 DTTPFKITTLKTTTLAPKVTTT 854 Score = 61.2 bits (147), Expect = 5e-09 Identities = 113/544 (20%), Positives = 176/544 (32%), Gaps = 67/544 (12%) Query: 381 PRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA 440 P+ P P P + P +P + P +P+ + P PA Sbjct: 306 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 365 Query: 441 VGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKIS 500 P + P+P + P PT++ S P T+ P +P +PK Sbjct: 366 PTTPKEPAPTTTKEPSPTTPKEP-------APTTTKSAPTTTKEPAPTTTKSAPTTPK-E 417 Query: 501 LAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPS 557 +PT KE + KEP T P++ A K P ++ + K Sbjct: 418 PSPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 476 Query: 558 SSPENSLDPFPPRILKEEPK---GKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAP 614 ++P+ + P ++ P+ E T E + + + +E P Sbjct: 477 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 536 Query: 615 SGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGP--VAEQVKKSTLNPNAKEFNPTKPL 672 + P++P P P + P E P A K T KE PT P Sbjct: 537 AAAPNTPKEPAPTTPKE----PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 592 Query: 673 LSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP 732 K + T+ P T +T P P G A P+ P P Sbjct: 593 KPAPKELAPTTTKEP-TSTTCDKPA-----------------PTTPKGTAPTTPK-EPAP 633 Query: 733 VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLV---AATPYSSYIP 789 + P KG+ P + +PA P A P +T P Sbjct: 634 TTPKEPAP----TTPKGTAP---TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 686 Query: 790 YNPQQ----FPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSS---STPQY 842 P++ P +PA P P+ P P S T+ P I S STP+ Sbjct: 687 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 746 Query: 843 PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTG--------SQPQSQHAAPSPV 894 + +PTP+AL + + A +P+ TT + P++ AAP Sbjct: 747 --SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 804 Query: 895 QHQA 898 + A Sbjct: 805 KETA 808 Score = 45.1 bits (105), Expect = 4e-04 Identities = 73/315 (23%), Positives = 110/315 (34%), Gaps = 59/315 (18%) Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464 P+ +PK P A T + P+ TS P P + P +PK AP P Sbjct: 655 PAPTTPKKPAPKELAPTTTKG---PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 711 Query: 465 PPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPT-DVKELSTKEPGRTLEPQEL 523 P TS S P T+ S ++P++S PT E S KEPG P Sbjct: 712 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG---VPTTK 768 Query: 524 ARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEV 583 A K + + +LR ++PE + P++ KE EK Sbjct: 769 TPAATKPEMTTTAKDKTTERDLR-----------TTPETT--TAAPKMTKETATTTEKTT 815 Query: 584 DGLLTSEPMGSPVSSKTESVSDKEDKP---------PLAPSGGT-----------EGPEQ 623 + +T+ +++ S + ++ P LAP T PE+ Sbjct: 816 ESKITA------TTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEE 869 Query: 624 PPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP- 682 P T S K P ++ K+ P + + T P + K+T TP Sbjct: 870 TAKPKDRATNS----------KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPR 919 Query: 683 --TSPGPRTHSTPSI 695 TS P + T I Sbjct: 920 KMTSTMPELNPTSRI 934 Score = 40.4 bits (93), Expect = 0.009 Identities = 79/372 (21%), Positives = 116/372 (31%), Gaps = 36/372 (9%) Query: 589 SEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEG 648 S P S S +T +KE + T + + + K KD Sbjct: 129 SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 188 Query: 649 PVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSP 708 P ++ + K T P A E P L+ K TPT+P +TP P T +S +P Sbjct: 189 PTSKVLAKPT--PKA-ETTTKGPALTTPKEP-TPTTPKEPASTTPKEPTPTTIKSAPTTP 244 Query: 709 QYIS-------------YIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQR 755 + + P PA P+ P P + P P Sbjct: 245 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPAP 303 Query: 756 SDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFA 815 + +PA P A P TP + P + P +P P +P A Sbjct: 304 TTPKKPAPTTPKEPAPTTPKEP----TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP--A 357 Query: 816 PMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHA----H 871 P P T +P P PT T + P T A Sbjct: 358 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE-PAPTTTKSAPTTPK 416 Query: 872 QPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGT---PPSLPP 928 +P P TT + + AP+ + A P +P A T T P+ P Sbjct: 417 EPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK----EPAPTTPKEPAPTTTKKPAPTTPK 472 Query: 929 GPSAQSPQSSFP 940 P+ +P+ + P Sbjct: 473 EPAPTTPKETAP 484 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 70.9 bits (172), Expect = 6e-12 Identities = 128/566 (22%), Positives = 197/566 (34%), Gaps = 71/566 (12%) Query: 394 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRP------SGETSVPPPPAVGRMYPP 447 P +A GP+ +PK P + S+ P S T+ P P Sbjct: 238 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 297 Query: 448 RSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVK 507 +PK AP P P A T+ P T+ + +P +PK APT Sbjct: 298 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPT--- 353 Query: 508 ELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPF 567 + KEP T P+E K P ++ + A K P++ E + Sbjct: 354 --TPKEPAPT-TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA---- 406 Query: 568 PPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP 627 P KE KE EP +P ++K+ + KE AP+ P P P Sbjct: 407 -PTTPKEPAPTTTKEPSPTTPKEP--APTTTKSAPTTTKEP----APTTTKSAPTTPKEP 459 Query: 628 CPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNK--STSTPTSP 685 P+ T P K+ P + T P +P + K + +TP P Sbjct: 460 SPTTTKEP----APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 515 Query: 686 GPRT--HSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK 743 P T + P+ P +P+ ++ P PA P+ ++ + P + Sbjct: 516 APTTPKETAPTTPKKLTPT----TPEKLA--PTTPEKPAPTTPE----ELAPTTPEE--- 562 Query: 744 YRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQ 803 P + +PA P +AAA P A T P P+ +PA Sbjct: 563 ---------PTPTTPEEPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPK----EPAPTT 607 Query: 804 PMAHYPSQPV-FAPMLQSNPRMLT-SGSHPQAIVSSST--PQYPSAEQPTPQALYATVHQ 859 P P+ P AP P T P+ + ++T P + ++P P T Sbjct: 608 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA-P 666 Query: 860 SYPHHATQLHAHQPQPATTPTGSQPQS-QHAAPSPVQHQAGQ--APHLGSGQPQQNLYHP 916 + P +P P TTP G+ P + + AP+ + A + AP G P Sbjct: 667 TTPKEPAPTTPKEPAP-TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 725 Query: 917 GALT--GTPPSLPPGPSAQSPQSSFP 940 T T P+ P P+ +P+ P Sbjct: 726 APTTPKETAPTTPKEPAPTTPKKPAP 751 Score = 67.8 bits (164), Expect = 5e-11 Identities = 124/579 (21%), Positives = 183/579 (31%), Gaps = 72/579 (12%) Query: 419 AKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASI 478 +K L+ P+ P ET+ P + P+ P P +++ P+ P PT+ S Sbjct: 232 SKVLAKPT--PKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEP----TPTTIKSA 281 Query: 479 PVTSSVSDPGVGSISPASPKISLAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQN 535 P T PA APT KE +TKEP T P+E A K P Sbjct: 282 PTTPK---------EPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKEPA--- 328 Query: 536 EQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSP 595 S+P +P P K P KE EP +P Sbjct: 329 -----------------PTTTKSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEP--TP 368 Query: 596 VSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG-SPPVGLIKGEDKDEGPVAEQV 654 + K + + KE P P++P P P + + P K+ P + Sbjct: 369 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 428 Query: 655 KKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYI 714 T +A + + +TP P P T P+ T + +P+ Sbjct: 429 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTTPK--KPA 484 Query: 715 PQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAA 774 P PA P+ P P + P A + P + + P + A Sbjct: 485 PTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTPEKLAPT 542 Query: 775 GPPLVAATPYSSYIPYNPQQ----FPGQPAMMQPMAHYPSQPVF-APMLQSNPRMLTSGS 829 P A T P P++ P +PA P A P+ P AP P T Sbjct: 543 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 602 Query: 830 HPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHA 889 + P P PT T+ + P + + P TT + Sbjct: 603 PAPTTPKETAPTTPKGTAPT------TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 656 Query: 890 APSPVQHQAGQAPHLGSGQPQQNLYHPGALT--GTPPSLPPGPSAQSPQSSFPQPAAVYA 947 AP+ + G AP P T GT P+ P+ +P+ P+ A Sbjct: 657 APTTPK---GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 713 Query: 948 IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPP 986 + P T+ +T T P P P P Sbjct: 714 ---TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP 749 Score = 62.8 bits (151), Expect = 2e-09 Identities = 107/502 (21%), Positives = 162/502 (32%), Gaps = 67/502 (13%) Query: 406 SRMSPKAQRPLRGAKTLSSPSN--RPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCP 463 ++ +P + T S+P+ PS T+ P P + P +PK AP P Sbjct: 434 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 493 Query: 464 EPPIGSAVPTSSASIPVTSSVSDPGV-GSISPASPKISLAPTDVKEL--STKEPGRTLEP 520 P A T+ P T P +P +PK L PT ++L +T E P Sbjct: 494 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTP 552 Query: 521 QELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFP-------PRILK 573 +ELA + P ++ +++P +P P P K Sbjct: 553 EELAPTTPEEPTPTTPEEPAP-----------TTPKAAAPNTPKEPAPTTPKEPAPTTPK 601 Query: 574 EEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG 633 E KE + P G+ ++ E KP T E C Sbjct: 602 EPAPTTPKET---APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 658 Query: 634 SPPVGLIKGEDKDEGPV-----AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPR 688 + P G K+ P A K T KE PT P K + T+ GP Sbjct: 659 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP- 717 Query: 689 THSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAK 748 T +T P T + P PA P+ P P + P Sbjct: 718 TSTTSDKPAPTTPK---------ETAPTTPKEPAPTTPKK-PAPTTPETP---------- 757 Query: 749 GSLPPQRSDQHQPASA--PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMA 806 PP S+ P + P + + P ++A P + +P++ PG P P A Sbjct: 758 ---PPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE-PGVPTTKTPAA 813 Query: 807 HYPSQPVFAP------MLQSNPRMLTSGSHPQAIVSSSTPQYPSAE--QPTPQALYATVH 858 P A L++ P T+ +++T + ++ T Q T Sbjct: 814 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 873 Query: 859 QSYPHHATQLHAHQPQPATTPT 880 + P T L P T T Sbjct: 874 DTTPFKITTLKTTTLAPKVTTT 895 Score = 61.2 bits (147), Expect = 5e-09 Identities = 113/544 (20%), Positives = 176/544 (32%), Gaps = 67/544 (12%) Query: 381 PRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA 440 P+ P P P + P +P + P +P+ + P PA Sbjct: 347 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 406 Query: 441 VGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKIS 500 P + P+P + P PT++ S P T+ P +P +PK Sbjct: 407 PTTPKEPAPTTTKEPSPTTPKEP-------APTTTKSAPTTTKEPAPTTTKSAPTTPK-E 458 Query: 501 LAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPS 557 +PT KE + KEP T P++ A K P ++ + K Sbjct: 459 PSPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 517 Query: 558 SSPENSLDPFPPRILKEEPK---GKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAP 614 ++P+ + P ++ P+ E T E + + + +E P Sbjct: 518 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 577 Query: 615 SGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGP--VAEQVKKSTLNPNAKEFNPTKPL 672 + P++P P P + P E P A K T KE PT P Sbjct: 578 AAAPNTPKEPAPTTPKE----PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 633 Query: 673 LSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP 732 K + T+ P T +T P P G A P+ P P Sbjct: 634 KPAPKELAPTTTKEP-TSTTCDKPA-----------------PTTPKGTAPTTPK-EPAP 674 Query: 733 VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLV---AATPYSSYIP 789 + P KG+ P + +PA P A P +T P Sbjct: 675 TTPKEPAP----TTPKGTAP---TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 727 Query: 790 YNPQQ----FPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSS---STPQY 842 P++ P +PA P P+ P P S T+ P I S STP+ Sbjct: 728 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 787 Query: 843 PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTG--------SQPQSQHAAPSPV 894 + +PTP+AL + + A +P+ TT + P++ AAP Sbjct: 788 --SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 845 Query: 895 QHQA 898 + A Sbjct: 846 KETA 849 Score = 45.1 bits (105), Expect = 4e-04 Identities = 73/315 (23%), Positives = 110/315 (34%), Gaps = 59/315 (18%) Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464 P+ +PK P A T + P+ TS P P + P +PK AP P Sbjct: 696 PAPTTPKKPAPKELAPTTTKG---PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 752 Query: 465 PPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPT-DVKELSTKEPGRTLEPQEL 523 P TS S P T+ S ++P++S PT E S KEPG P Sbjct: 753 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG---VPTTK 809 Query: 524 ARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEV 583 A K + + +LR ++PE + P++ KE EK Sbjct: 810 TPAATKPEMTTTAKDKTTERDLR-----------TTPETT--TAAPKMTKETATTTEKTT 856 Query: 584 DGLLTSEPMGSPVSSKTESVSDKEDKP---------PLAPSGGT-----------EGPEQ 623 + +T+ +++ S + ++ P LAP T PE+ Sbjct: 857 ESKITA------TTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEE 910 Query: 624 PPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP- 682 P T S K P ++ K+ P + + T P + K+T TP Sbjct: 911 TAKPKDRATNS----------KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPR 960 Query: 683 --TSPGPRTHSTPSI 695 TS P + T I Sbjct: 961 KMTSTMPELNPTSRI 975 Score = 40.4 bits (93), Expect = 0.009 Identities = 79/372 (21%), Positives = 116/372 (31%), Gaps = 36/372 (9%) Query: 589 SEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEG 648 S P S S +T +KE + T + + + K KD Sbjct: 170 SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 229 Query: 649 PVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSP 708 P ++ + K T P A E P L+ K TPT+P +TP P T +S +P Sbjct: 230 PTSKVLAKPT--PKA-ETTTKGPALTTPKEP-TPTTPKEPASTTPKEPTPTTIKSAPTTP 285 Query: 709 QYIS-------------YIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQR 755 + + P PA P+ P P + P P Sbjct: 286 KEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPAP 344 Query: 756 SDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFA 815 + +PA P A P TP + P + P +P P +P A Sbjct: 345 TTPKKPAPTTPKEPAPTTPKEP----TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP--A 398 Query: 816 PMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHA----H 871 P P T +P P PT T + P T A Sbjct: 399 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE-PAPTTTKSAPTTPK 457 Query: 872 QPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGT---PPSLPP 928 +P P TT + + AP+ + A P +P A T T P+ P Sbjct: 458 EPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPK----EPAPTTPKEPAPTTTKKPAPTTPK 513 Query: 929 GPSAQSPQSSFP 940 P+ +P+ + P Sbjct: 514 EPAPTTPKETAP 525 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 70.9 bits (172), Expect = 6e-12 Identities = 128/566 (22%), Positives = 197/566 (34%), Gaps = 71/566 (12%) Query: 394 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRP------SGETSVPPPPAVGRMYPP 447 P +A GP+ +PK P + S+ P S T+ P P Sbjct: 290 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 349 Query: 448 RSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVK 507 +PK AP P P A T+ P T+ + +P +PK APT Sbjct: 350 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPT--- 405 Query: 508 ELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPF 567 + KEP T P+E K P ++ + A K P++ E + Sbjct: 406 --TPKEPAPT-TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA---- 458 Query: 568 PPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP 627 P KE KE EP +P ++K+ + KE AP+ P P P Sbjct: 459 -PTTPKEPAPTTTKEPSPTTPKEP--APTTTKSAPTTTKEP----APTTTKSAPTTPKEP 511 Query: 628 CPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNK--STSTPTSP 685 P+ T P K+ P + T P +P + K + +TP P Sbjct: 512 SPTTTKEP----APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 567 Query: 686 GPRT--HSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK 743 P T + P+ P +P+ ++ P PA P+ ++ + P + Sbjct: 568 APTTPKETAPTTPKKLTPT----TPEKLA--PTTPEKPAPTTPE----ELAPTTPEE--- 614 Query: 744 YRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQ 803 P + +PA P +AAA P A T P P+ +PA Sbjct: 615 ---------PTPTTPEEPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPK----EPAPTT 659 Query: 804 PMAHYPSQPV-FAPMLQSNPRMLT-SGSHPQAIVSSST--PQYPSAEQPTPQALYATVHQ 859 P P+ P AP P T P+ + ++T P + ++P P T Sbjct: 660 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA-P 718 Query: 860 SYPHHATQLHAHQPQPATTPTGSQPQS-QHAAPSPVQHQAGQ--APHLGSGQPQQNLYHP 916 + P +P P TTP G+ P + + AP+ + A + AP G P Sbjct: 719 TTPKEPAPTTPKEPAP-TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 777 Query: 917 GALT--GTPPSLPPGPSAQSPQSSFP 940 T T P+ P P+ +P+ P Sbjct: 778 APTTPKETAPTTPKEPAPTTPKKPAP 803 Score = 67.8 bits (164), Expect = 5e-11 Identities = 124/579 (21%), Positives = 183/579 (31%), Gaps = 72/579 (12%) Query: 419 AKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASI 478 +K L+ P+ P ET+ P + P+ P P +++ P+ P PT+ S Sbjct: 284 SKVLAKPT--PKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEP----TPTTIKSA 333 Query: 479 PVTSSVSDPGVGSISPASPKISLAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQN 535 P T PA APT KE +TKEP T P+E A K P Sbjct: 334 PTTPK---------EPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKEPA--- 380 Query: 536 EQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSP 595 S+P +P P K P KE EP +P Sbjct: 381 -----------------PTTTKSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEP--TP 420 Query: 596 VSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG-SPPVGLIKGEDKDEGPVAEQV 654 + K + + KE P P++P P P + + P K+ P + Sbjct: 421 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 480 Query: 655 KKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYI 714 T +A + + +TP P P T P+ T + +P+ Sbjct: 481 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTTPK--KPA 536 Query: 715 PQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAA 774 P PA P+ P P + P A + P + + P + A Sbjct: 537 PTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTPEKLAPT 594 Query: 775 GPPLVAATPYSSYIPYNPQQ----FPGQPAMMQPMAHYPSQPVF-APMLQSNPRMLTSGS 829 P A T P P++ P +PA P A P+ P AP P T Sbjct: 595 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 654 Query: 830 HPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHA 889 + P P PT T+ + P + + P TT + Sbjct: 655 PAPTTPKETAPTTPKGTAPT------TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 708 Query: 890 APSPVQHQAGQAPHLGSGQPQQNLYHPGALT--GTPPSLPPGPSAQSPQSSFPQPAAVYA 947 AP+ + G AP P T GT P+ P+ +P+ P+ A Sbjct: 709 APTTPK---GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 765 Query: 948 IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPP 986 + P T+ +T T P P P P Sbjct: 766 ---TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP 801 Score = 62.8 bits (151), Expect = 2e-09 Identities = 107/502 (21%), Positives = 162/502 (32%), Gaps = 67/502 (13%) Query: 406 SRMSPKAQRPLRGAKTLSSPSN--RPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCP 463 ++ +P + T S+P+ PS T+ P P + P +PK AP P Sbjct: 486 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 545 Query: 464 EPPIGSAVPTSSASIPVTSSVSDPGV-GSISPASPKISLAPTDVKEL--STKEPGRTLEP 520 P A T+ P T P +P +PK L PT ++L +T E P Sbjct: 546 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTP 604 Query: 521 QELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFP-------PRILK 573 +ELA + P ++ +++P +P P P K Sbjct: 605 EELAPTTPEEPTPTTPEEPAP-----------TTPKAAAPNTPKEPAPTTPKEPAPTTPK 653 Query: 574 EEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG 633 E KE + P G+ ++ E KP T E C Sbjct: 654 EPAPTTPKET---APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 710 Query: 634 SPPVGLIKGEDKDEGPV-----AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPR 688 + P G K+ P A K T KE PT P K + T+ GP Sbjct: 711 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP- 769 Query: 689 THSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAK 748 T +T P T + P PA P+ P P + P Sbjct: 770 TSTTSDKPAPTTPK---------ETAPTTPKEPAPTTPKK-PAPTTPETP---------- 809 Query: 749 GSLPPQRSDQHQPASA--PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMA 806 PP S+ P + P + + P ++A P + +P++ PG P P A Sbjct: 810 ---PPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE-PGVPTTKTPAA 865 Query: 807 HYPSQPVFAP------MLQSNPRMLTSGSHPQAIVSSSTPQYPSAE--QPTPQALYATVH 858 P A L++ P T+ +++T + ++ T Q T Sbjct: 866 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 925 Query: 859 QSYPHHATQLHAHQPQPATTPT 880 + P T L P T T Sbjct: 926 DTTPFKITTLKTTTLAPKVTTT 947 Score = 61.2 bits (147), Expect = 5e-09 Identities = 113/544 (20%), Positives = 176/544 (32%), Gaps = 67/544 (12%) Query: 381 PRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA 440 P+ P P P + P +P + P +P+ + P PA Sbjct: 399 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 458 Query: 441 VGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKIS 500 P + P+P + P PT++ S P T+ P +P +PK Sbjct: 459 PTTPKEPAPTTTKEPSPTTPKEP-------APTTTKSAPTTTKEPAPTTTKSAPTTPK-E 510 Query: 501 LAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPS 557 +PT KE + KEP T P++ A K P ++ + K Sbjct: 511 PSPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 569 Query: 558 SSPENSLDPFPPRILKEEPK---GKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAP 614 ++P+ + P ++ P+ E T E + + + +E P Sbjct: 570 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 629 Query: 615 SGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGP--VAEQVKKSTLNPNAKEFNPTKPL 672 + P++P P P + P E P A K T KE PT P Sbjct: 630 AAAPNTPKEPAPTTPKE----PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 685 Query: 673 LSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP 732 K + T+ P T +T P P G A P+ P P Sbjct: 686 KPAPKELAPTTTKEP-TSTTCDKPA-----------------PTTPKGTAPTTPK-EPAP 726 Query: 733 VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLV---AATPYSSYIP 789 + P KG+ P + +PA P A P +T P Sbjct: 727 TTPKEPAP----TTPKGTAP---TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 779 Query: 790 YNPQQ----FPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSS---STPQY 842 P++ P +PA P P+ P P S T+ P I S STP+ Sbjct: 780 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 839 Query: 843 PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTG--------SQPQSQHAAPSPV 894 + +PTP+AL + + A +P+ TT + P++ AAP Sbjct: 840 --SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 897 Query: 895 QHQA 898 + A Sbjct: 898 KETA 901 Score = 45.1 bits (105), Expect = 4e-04 Identities = 73/315 (23%), Positives = 110/315 (34%), Gaps = 59/315 (18%) Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464 P+ +PK P A T + P+ TS P P + P +PK AP P Sbjct: 748 PAPTTPKKPAPKELAPTTTKG---PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 804 Query: 465 PPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPT-DVKELSTKEPGRTLEPQEL 523 P TS S P T+ S ++P++S PT E S KEPG P Sbjct: 805 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG---VPTTK 861 Query: 524 ARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEV 583 A K + + +LR ++PE + P++ KE EK Sbjct: 862 TPAATKPEMTTTAKDKTTERDLR-----------TTPETT--TAAPKMTKETATTTEKTT 908 Query: 584 DGLLTSEPMGSPVSSKTESVSDKEDKP---------PLAPSGGT-----------EGPEQ 623 + +T+ +++ S + ++ P LAP T PE+ Sbjct: 909 ESKITA------TTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEE 962 Query: 624 PPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP- 682 P T S K P ++ K+ P + + T P + K+T TP Sbjct: 963 TAKPKDRATNS----------KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPR 1012 Query: 683 --TSPGPRTHSTPSI 695 TS P + T I Sbjct: 1013 KMTSTMPELNPTSRI 1027 Score = 43.5 bits (101), Expect = 0.001 Identities = 109/536 (20%), Positives = 174/536 (32%), Gaps = 50/536 (9%) Query: 432 ETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGS 491 E P P + PP S S + P+PP S +T S Sbjct: 65 EVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQE 124 Query: 492 ISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGA- 550 S +S S + T K S+K E Q+ ++ ++ + + + G+ Sbjct: 125 SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSG 184 Query: 551 ----QFKLQP--SSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVS 604 FK+ +S+ +++ P+I +P + + S +K +V Sbjct: 185 LDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVE 244 Query: 605 DKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAK 664 KE + T+G E+ +Q+ + K KD P ++ + K T P A Sbjct: 245 TKETTTTNKQTS-TDGKEKTTSAKETQS------IEKTSAKDLAPTSKVLAKPT--PKA- 294 Query: 665 EFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYIS------------ 712 E P L+ K TPT+P +TP P T +S +P+ + Sbjct: 295 ETTTKGPALTTPKEP-TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPK 353 Query: 713 -YIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAA 771 P PA P+ P P + P P + +PA P A Sbjct: 354 EPAPTTTKEPAPTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP 412 Query: 772 AAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHP 831 P TP + P + P +P P +P AP P T Sbjct: 413 TTPKEP----TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP--APTTPKEPAPTTPKEPA 466 Query: 832 QAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHA----HQPQPATTPTGSQPQSQ 887 +P P PT T + P T A +P P TT + + Sbjct: 467 PTTTKEPSPTTPKEPAPTTTKSAPTTTKE-PAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 525 Query: 888 HAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGT---PPSLPPGPSAQSPQSSFP 940 AP+ + A P +P A T T P+ P P+ +P+ + P Sbjct: 526 EPAPTTPKKPAPTTPK----EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAP 577 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 70.9 bits (172), Expect = 6e-12 Identities = 128/566 (22%), Positives = 197/566 (34%), Gaps = 71/566 (12%) Query: 394 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRP------SGETSVPPPPAVGRMYPP 447 P +A GP+ +PK P + S+ P S T+ P P Sbjct: 331 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 390 Query: 448 RSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVK 507 +PK AP P P A T+ P T+ + +P +PK APT Sbjct: 391 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPT--- 446 Query: 508 ELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPF 567 + KEP T P+E K P ++ + A K P++ E + Sbjct: 447 --TPKEPAPT-TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA---- 499 Query: 568 PPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP 627 P KE KE EP +P ++K+ + KE AP+ P P P Sbjct: 500 -PTTPKEPAPTTTKEPSPTTPKEP--APTTTKSAPTTTKEP----APTTTKSAPTTPKEP 552 Query: 628 CPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNK--STSTPTSP 685 P+ T P K+ P + T P +P + K + +TP P Sbjct: 553 SPTTTKEP----APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 608 Query: 686 GPRT--HSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK 743 P T + P+ P +P+ ++ P PA P+ ++ + P + Sbjct: 609 APTTPKETAPTTPKKLTPT----TPEKLA--PTTPEKPAPTTPE----ELAPTTPEE--- 655 Query: 744 YRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQ 803 P + +PA P +AAA P A T P P+ +PA Sbjct: 656 ---------PTPTTPEEPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPK----EPAPTT 700 Query: 804 PMAHYPSQPV-FAPMLQSNPRMLT-SGSHPQAIVSSST--PQYPSAEQPTPQALYATVHQ 859 P P+ P AP P T P+ + ++T P + ++P P T Sbjct: 701 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA-P 759 Query: 860 SYPHHATQLHAHQPQPATTPTGSQPQS-QHAAPSPVQHQAGQ--APHLGSGQPQQNLYHP 916 + P +P P TTP G+ P + + AP+ + A + AP G P Sbjct: 760 TTPKEPAPTTPKEPAP-TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 818 Query: 917 GALT--GTPPSLPPGPSAQSPQSSFP 940 T T P+ P P+ +P+ P Sbjct: 819 APTTPKETAPTTPKEPAPTTPKKPAP 844 Score = 67.8 bits (164), Expect = 5e-11 Identities = 124/579 (21%), Positives = 183/579 (31%), Gaps = 72/579 (12%) Query: 419 AKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASI 478 +K L+ P+ P ET+ P + P+ P P +++ P+ P PT+ S Sbjct: 325 SKVLAKPT--PKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEP----TPTTIKSA 374 Query: 479 PVTSSVSDPGVGSISPASPKISLAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQN 535 P T PA APT KE +TKEP T P+E A K P Sbjct: 375 PTTPK---------EPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKEPA--- 421 Query: 536 EQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSP 595 S+P +P P K P KE EP +P Sbjct: 422 -----------------PTTTKSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEP--TP 461 Query: 596 VSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG-SPPVGLIKGEDKDEGPVAEQV 654 + K + + KE P P++P P P + + P K+ P + Sbjct: 462 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 521 Query: 655 KKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYI 714 T +A + + +TP P P T P+ T + +P+ Sbjct: 522 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTTPK--KPA 577 Query: 715 PQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAA 774 P PA P+ P P + P A + P + + P + A Sbjct: 578 PTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTPEKLAPT 635 Query: 775 GPPLVAATPYSSYIPYNPQQ----FPGQPAMMQPMAHYPSQPVF-APMLQSNPRMLTSGS 829 P A T P P++ P +PA P A P+ P AP P T Sbjct: 636 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 695 Query: 830 HPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHA 889 + P P PT T+ + P + + P TT + Sbjct: 696 PAPTTPKETAPTTPKGTAPT------TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 749 Query: 890 APSPVQHQAGQAPHLGSGQPQQNLYHPGALT--GTPPSLPPGPSAQSPQSSFPQPAAVYA 947 AP+ + G AP P T GT P+ P+ +P+ P+ A Sbjct: 750 APTTPK---GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 806 Query: 948 IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPP 986 + P T+ +T T P P P P Sbjct: 807 ---TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP 842 Score = 62.8 bits (151), Expect = 2e-09 Identities = 107/502 (21%), Positives = 162/502 (32%), Gaps = 67/502 (13%) Query: 406 SRMSPKAQRPLRGAKTLSSPSN--RPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCP 463 ++ +P + T S+P+ PS T+ P P + P +PK AP P Sbjct: 527 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 586 Query: 464 EPPIGSAVPTSSASIPVTSSVSDPGV-GSISPASPKISLAPTDVKEL--STKEPGRTLEP 520 P A T+ P T P +P +PK L PT ++L +T E P Sbjct: 587 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTP 645 Query: 521 QELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFP-------PRILK 573 +ELA + P ++ +++P +P P P K Sbjct: 646 EELAPTTPEEPTPTTPEEPAP-----------TTPKAAAPNTPKEPAPTTPKEPAPTTPK 694 Query: 574 EEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG 633 E KE + P G+ ++ E KP T E C Sbjct: 695 EPAPTTPKET---APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 751 Query: 634 SPPVGLIKGEDKDEGPV-----AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPR 688 + P G K+ P A K T KE PT P K + T+ GP Sbjct: 752 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP- 810 Query: 689 THSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAK 748 T +T P T + P PA P+ P P + P Sbjct: 811 TSTTSDKPAPTTPK---------ETAPTTPKEPAPTTPKK-PAPTTPETP---------- 850 Query: 749 GSLPPQRSDQHQPASA--PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMA 806 PP S+ P + P + + P ++A P + +P++ PG P P A Sbjct: 851 ---PPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE-PGVPTTKTPAA 906 Query: 807 HYPSQPVFAP------MLQSNPRMLTSGSHPQAIVSSSTPQYPSAE--QPTPQALYATVH 858 P A L++ P T+ +++T + ++ T Q T Sbjct: 907 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 966 Query: 859 QSYPHHATQLHAHQPQPATTPT 880 + P T L P T T Sbjct: 967 DTTPFKITTLKTTTLAPKVTTT 988 Score = 61.2 bits (147), Expect = 5e-09 Identities = 113/544 (20%), Positives = 176/544 (32%), Gaps = 67/544 (12%) Query: 381 PRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA 440 P+ P P P + P +P + P +P+ + P PA Sbjct: 440 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 499 Query: 441 VGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKIS 500 P + P+P + P PT++ S P T+ P +P +PK Sbjct: 500 PTTPKEPAPTTTKEPSPTTPKEP-------APTTTKSAPTTTKEPAPTTTKSAPTTPK-E 551 Query: 501 LAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPS 557 +PT KE + KEP T P++ A K P ++ + K Sbjct: 552 PSPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 610 Query: 558 SSPENSLDPFPPRILKEEPK---GKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAP 614 ++P+ + P ++ P+ E T E + + + +E P Sbjct: 611 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 670 Query: 615 SGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGP--VAEQVKKSTLNPNAKEFNPTKPL 672 + P++P P P + P E P A K T KE PT P Sbjct: 671 AAAPNTPKEPAPTTPKE----PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 726 Query: 673 LSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP 732 K + T+ P T +T P P G A P+ P P Sbjct: 727 KPAPKELAPTTTKEP-TSTTCDKPA-----------------PTTPKGTAPTTPK-EPAP 767 Query: 733 VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLV---AATPYSSYIP 789 + P KG+ P + +PA P A P +T P Sbjct: 768 TTPKEPAP----TTPKGTAP---TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 820 Query: 790 YNPQQ----FPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSS---STPQY 842 P++ P +PA P P+ P P S T+ P I S STP+ Sbjct: 821 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 880 Query: 843 PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTG--------SQPQSQHAAPSPV 894 + +PTP+AL + + A +P+ TT + P++ AAP Sbjct: 881 --SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 938 Query: 895 QHQA 898 + A Sbjct: 939 KETA 942 Score = 45.1 bits (105), Expect = 4e-04 Identities = 73/315 (23%), Positives = 110/315 (34%), Gaps = 59/315 (18%) Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464 P+ +PK P A T + P+ TS P P + P +PK AP P Sbjct: 789 PAPTTPKKPAPKELAPTTTKG---PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 845 Query: 465 PPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPT-DVKELSTKEPGRTLEPQEL 523 P TS S P T+ S ++P++S PT E S KEPG P Sbjct: 846 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG---VPTTK 902 Query: 524 ARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEV 583 A K + + +LR ++PE + P++ KE EK Sbjct: 903 TPAATKPEMTTTAKDKTTERDLR-----------TTPETT--TAAPKMTKETATTTEKTT 949 Query: 584 DGLLTSEPMGSPVSSKTESVSDKEDKP---------PLAPSGGT-----------EGPEQ 623 + +T+ +++ S + ++ P LAP T PE+ Sbjct: 950 ESKITA------TTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEE 1003 Query: 624 PPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP- 682 P T S K P ++ K+ P + + T P + K+T TP Sbjct: 1004 TAKPKDRATNS----------KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPR 1053 Query: 683 --TSPGPRTHSTPSI 695 TS P + T I Sbjct: 1054 KMTSTMPELNPTSRI 1068 Score = 43.5 bits (101), Expect = 0.001 Identities = 109/536 (20%), Positives = 174/536 (32%), Gaps = 50/536 (9%) Query: 432 ETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGS 491 E P P + PP S S + P+PP S +T S Sbjct: 106 EVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQE 165 Query: 492 ISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGA- 550 S +S S + T K S+K E Q+ ++ ++ + + + G+ Sbjct: 166 SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSG 225 Query: 551 ----QFKLQP--SSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVS 604 FK+ +S+ +++ P+I +P + + S +K +V Sbjct: 226 LDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVE 285 Query: 605 DKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAK 664 KE + T+G E+ +Q+ + K KD P ++ + K T P A Sbjct: 286 TKETTTTNKQTS-TDGKEKTTSAKETQS------IEKTSAKDLAPTSKVLAKPT--PKA- 335 Query: 665 EFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYIS------------ 712 E P L+ K TPT+P +TP P T +S +P+ + Sbjct: 336 ETTTKGPALTTPKEP-TPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPK 394 Query: 713 -YIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAA 771 P PA P+ P P + P P + +PA P A Sbjct: 395 EPAPTTTKEPAPTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP 453 Query: 772 AAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHP 831 P TP + P + P +P P +P AP P T Sbjct: 454 TTPKEP----TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP--APTTPKEPAPTTPKEPA 507 Query: 832 QAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHA----HQPQPATTPTGSQPQSQ 887 +P P PT T + P T A +P P TT + + Sbjct: 508 PTTTKEPSPTTPKEPAPTTTKSAPTTTKE-PAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 566 Query: 888 HAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGT---PPSLPPGPSAQSPQSSFP 940 AP+ + A P +P A T T P+ P P+ +P+ + P Sbjct: 567 EPAPTTPKKPAPTTPK----EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAP 618 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.309 0.129 0.387 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 61,823,397 Number of Sequences: 37866 Number of extensions: 4534277 Number of successful extensions: 51760 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 364 Number of HSP's successfully gapped in prelim test: 2389 Number of HSP's that attempted gapping in prelim test: 22734 Number of HSP's gapped (non-prelim): 21927 length of query: 1075 length of database: 18,247,518 effective HSP length: 113 effective length of query: 962 effective length of database: 13,968,660 effective search space: 13437850920 effective search space used: 13437850920 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.