BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|27262645 ataxin 2 related protein isoform B [Homo sapiens] (1062 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|27262645 ataxin 2 related protein isoform B [Homo sapiens] 2183 0.0 gi|27262649 ataxin 2 related protein isoform C [Homo sapiens] 2151 0.0 gi|27262647 ataxin 2 related protein isoform A [Homo sapiens] 2151 0.0 gi|27262653 ataxin 2 related protein isoform E [Homo sapiens] 2130 0.0 gi|27262651 ataxin 2 related protein isoform D [Homo sapiens] 2112 0.0 gi|171543895 ataxin 2 [Homo sapiens] 610 e-174 gi|163965366 nascent polypeptide-associated complex alpha subuni... 110 9e-24 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 104 4e-22 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 98 4e-20 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 97 8e-20 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 92 3e-18 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 87 1e-16 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 87 1e-16 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 85 3e-16 gi|150170670 piccolo isoform 2 [Homo sapiens] 81 6e-15 gi|150378539 piccolo isoform 1 [Homo sapiens] 81 6e-15 gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 80 1e-14 gi|55750053 atrophin-1 [Homo sapiens] 78 4e-14 gi|55750041 atrophin-1 [Homo sapiens] 78 4e-14 gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 74 6e-13 gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 74 6e-13 gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 74 7e-13 gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 74 1e-12 gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 73 1e-12 gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 72 3e-12 gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 72 4e-12 gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 72 4e-12 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 71 6e-12 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 71 6e-12 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 71 6e-12 >gi|27262645 ataxin 2 related protein isoform B [Homo sapiens] Length = 1062 Score = 2183 bits (5657), Expect = 0.0 Identities = 1062/1062 (100%), Positives = 1062/1062 (100%) Query: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG Sbjct: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN Sbjct: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120 Query: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV Sbjct: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180 Query: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD Sbjct: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240 Query: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA Sbjct: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300 Query: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP Sbjct: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360 Query: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK Sbjct: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420 Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV Sbjct: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480 Query: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF Sbjct: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540 Query: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT Sbjct: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600 Query: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN Sbjct: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660 Query: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG Sbjct: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720 Query: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA Sbjct: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780 Query: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP Sbjct: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840 Query: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ Sbjct: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900 Query: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM Sbjct: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960 Query: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP Sbjct: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020 Query: 1021 YPYIGHPQGEQPGQAPGFPGGADDRIPPLPPPGELKIVLAAT 1062 YPYIGHPQGEQPGQAPGFPGGADDRIPPLPPPGELKIVLAAT Sbjct: 1021 YPYIGHPQGEQPGQAPGFPGGADDRIPPLPPPGELKIVLAAT 1062 >gi|27262649 ataxin 2 related protein isoform C [Homo sapiens] Length = 1097 Score = 2151 bits (5573), Expect = 0.0 Identities = 1046/1046 (100%), Positives = 1046/1046 (100%) Query: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG Sbjct: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN Sbjct: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120 Query: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV Sbjct: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180 Query: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD Sbjct: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240 Query: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA Sbjct: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300 Query: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP Sbjct: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360 Query: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK Sbjct: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420 Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV Sbjct: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480 Query: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF Sbjct: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540 Query: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT Sbjct: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600 Query: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN Sbjct: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660 Query: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG Sbjct: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720 Query: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA Sbjct: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780 Query: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP Sbjct: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840 Query: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ Sbjct: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900 Query: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM Sbjct: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960 Query: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP Sbjct: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020 Query: 1021 YPYIGHPQGEQPGQAPGFPGGADDRI 1046 YPYIGHPQGEQPGQAPGFPGGADDRI Sbjct: 1021 YPYIGHPQGEQPGQAPGFPGGADDRI 1046 Score = 38.1 bits (87), Expect = 0.044 Identities = 24/76 (31%), Positives = 29/76 (38%), Gaps = 2/76 (2%) Query: 977 PPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAP 1036 P P P P Q + P PP G +P G A SA+ P P G Sbjct: 10 PSQPQQPPPTQQAVARRPPGGTSPPNGGLP--GPLATSAAPPGPPAAASPCLGPVAAAGS 67 Query: 1037 GFPGGADDRIPPLPPP 1052 G GA+ + P PPP Sbjct: 68 GLRRGAEGILAPQPPP 83 >gi|27262647 ataxin 2 related protein isoform A [Homo sapiens] Length = 1075 Score = 2151 bits (5573), Expect = 0.0 Identities = 1046/1046 (100%), Positives = 1046/1046 (100%) Query: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG Sbjct: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN Sbjct: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120 Query: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV Sbjct: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180 Query: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD Sbjct: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240 Query: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA Sbjct: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300 Query: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP Sbjct: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360 Query: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK Sbjct: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420 Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV Sbjct: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480 Query: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF Sbjct: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540 Query: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT Sbjct: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600 Query: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN Sbjct: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660 Query: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG Sbjct: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720 Query: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA Sbjct: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780 Query: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP Sbjct: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840 Query: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ Sbjct: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900 Query: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM Sbjct: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960 Query: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP Sbjct: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020 Query: 1021 YPYIGHPQGEQPGQAPGFPGGADDRI 1046 YPYIGHPQGEQPGQAPGFPGGADDRI Sbjct: 1021 YPYIGHPQGEQPGQAPGFPGGADDRI 1046 Score = 38.1 bits (87), Expect = 0.044 Identities = 24/76 (31%), Positives = 29/76 (38%), Gaps = 2/76 (2%) Query: 977 PPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAP 1036 P P P P Q + P PP G +P G A SA+ P P G Sbjct: 10 PSQPQQPPPTQQAVARRPPGGTSPPNGGLP--GPLATSAAPPGPPAAASPCLGPVAAAGS 67 Query: 1037 GFPGGADDRIPPLPPP 1052 G GA+ + P PPP Sbjct: 68 GLRRGAEGILAPQPPP 83 >gi|27262653 ataxin 2 related protein isoform E [Homo sapiens] Length = 1044 Score = 2130 bits (5520), Expect = 0.0 Identities = 1043/1062 (98%), Positives = 1043/1062 (98%), Gaps = 18/1062 (1%) Query: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG Sbjct: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN Sbjct: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120 Query: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV Sbjct: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180 Query: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD Sbjct: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240 Query: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA Sbjct: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300 Query: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP Sbjct: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360 Query: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK Sbjct: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420 Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV Sbjct: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480 Query: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF Sbjct: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540 Query: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT Sbjct: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600 Query: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN Sbjct: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660 Query: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG Sbjct: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720 Query: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA Sbjct: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780 Query: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP Sbjct: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840 Query: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ Sbjct: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900 Query: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM Sbjct: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960 Query: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP Sbjct: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020 Query: 1021 YPYIGHPQGEQPGQAPGFPGGADDRIPPLPPPGELKIVLAAT 1062 YPYIGHPQ PLPPPGELKIVLAAT Sbjct: 1021 YPYIGHPQA------------------PLPPPGELKIVLAAT 1044 >gi|27262651 ataxin 2 related protein isoform D [Homo sapiens] Length = 1044 Score = 2112 bits (5473), Expect = 0.0 Identities = 1032/1043 (98%), Positives = 1032/1043 (98%), Gaps = 2/1043 (0%) Query: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG Sbjct: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN Sbjct: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120 Query: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV Sbjct: 121 SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180 Query: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD Sbjct: 181 DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240 Query: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA Sbjct: 241 YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300 Query: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP Sbjct: 301 REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360 Query: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK Sbjct: 361 RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420 Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV Sbjct: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480 Query: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF Sbjct: 481 TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540 Query: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT Sbjct: 541 QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600 Query: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN Sbjct: 601 ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660 Query: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG Sbjct: 661 PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720 Query: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA Sbjct: 721 PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780 Query: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP Sbjct: 781 ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840 Query: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ Sbjct: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900 Query: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM Sbjct: 901 APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960 Query: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP Sbjct: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020 Query: 1021 YPYIGHP--QGEQPGQAPGFPGG 1041 YPYIGHP Q Q P P G Sbjct: 1021 YPYIGHPQVQSHPSQQLPFHPPG 1043 Score = 38.1 bits (87), Expect = 0.044 Identities = 24/76 (31%), Positives = 29/76 (38%), Gaps = 2/76 (2%) Query: 977 PPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAP 1036 P P P P Q + P PP G +P G A SA+ P P G Sbjct: 10 PSQPQQPPPTQQAVARRPPGGTSPPNGGLP--GPLATSAAPPGPPAAASPCLGPVAAAGS 67 Query: 1037 GFPGGADDRIPPLPPP 1052 G GA+ + P PPP Sbjct: 68 GLRRGAEGILAPQPPP 83 >gi|171543895 ataxin 2 [Homo sapiens] Length = 1313 Score = 610 bits (1574), Expect = e-174 Identities = 455/1196 (38%), Positives = 613/1196 (51%), Gaps = 225/1196 (18%) Query: 2 LKPQPLQQPSQPQQPPPTQQAVARR--PPGGTSPPNGGLPGPLATSAAPPGPPAAASPCL 59 LKPQ QQ Q QQ QQ ++ PP + G G LA+ AA P P ++S Sbjct: 163 LKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSP--SSSSVS 220 Query: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPV-FEGVY 118 A A S + G P G RG+++ KG PQS + F+G+Y Sbjct: 221 SSSATAPSSVVAATSGGGRP-----------------GLGRGRNSNKGLPQSTISFDGIY 263 Query: 119 NNSRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRRED 178 N RM+H LT+VVGS C+V+VKNG YEG+FKT S K +L +DA H K++E + GP+RE+ Sbjct: 264 ANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREE 323 Query: 179 IVDTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGD--S 236 I+++++FK SD ++V F+++D +YA +D FTDSAI+ +KVNGEHKEK L+ W+ G+ + Sbjct: 324 IMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAIS--AKVNGEHKEKDLEPWDAGELTA 381 Query: 237 NSDDYDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRA 296 N + LE+D+SNGWDPN+MF++NEENYGV +TYDSSLSSYTVPLE+DNSEEF +RE RA Sbjct: 382 NEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARA 441 Query: 297 AQLAREIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRV 356 QLA EIESS QY+ R+A+ENDD R+EEEK++AVQR S RE S+ +RE KYIP QR Sbjct: 442 NQLAEEIESSAQYKARVALENDD-RSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQRN 500 Query: 357 REG-PRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGG---PSRM-SPK 411 RE G R +S R G+PG S+P R H + +P GS+ R +NGG PS SP Sbjct: 501 REVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPS 560 Query: 412 AQRPLR----------GAKTLSSPSNRPSGETSVPP---------------PPAVGRMYP 446 ++ P R A T + P +RP S PP P + P Sbjct: 561 SRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGP 620 Query: 447 PR-SPK----------SAAPAPISASCP----EPPIGSAVPTSSASIPVTSSVSD--PGV 489 PR SPK SA IS+ PP +A P + + P + S GV Sbjct: 621 PRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGV 680 Query: 490 GSISP----------------------ASPKISLAPTDVKELSTKEPGRTLEPQELARIA 527 +SP ASP+ + PT+ ++ P + P A Sbjct: 681 PRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEA--VAMPIPAASPTPASPASNR 738 Query: 528 GKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN-SLDPFPPRILKEEPKG-------K 579 P + + R Q Q + P+ + EN + P K E KG Sbjct: 739 AVTPSSEAKDSRLQ--------DQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEH 790 Query: 580 EKEVDGL------------LTSEPMGSPVSSKTE-------------------------- 601 K++D L TSE M ++ E Sbjct: 791 RKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSS 850 Query: 602 ---SVSDKEDKPPLAPSGGTEGPEQPPPPCPS---QTGSPPVGLIKGEDKDEGPVAEQVK 655 S S K + P ++PS + + P S QT SP K + +++ AEQV+ Sbjct: 851 NCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVR 910 Query: 656 KSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSI-----PVLTAGQSGLYSPQY 710 KSTLNPNAKEFNP S K ++TPTSP P+ +PS+ P Q ++P Sbjct: 911 KSTLNPNAKEFNPRS--FSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNM 968 Query: 711 ISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQA 770 + +P + P VQ +YP P++ +P Q K A ++P QR DQH ++ MM Sbjct: 969 MYPVP---VSPGVQ--PLYPIPMT-PMPVNQAKTYRAVPNMPQQRQDQHHQSA---MMHP 1019 Query: 771 AAAAGPPLVAATP-YSS-YIPYNPQQFPGQPAMMQPMAHYPSQ--PVFAPMLQSNPRMLT 826 A+AAGPP+ A P YS+ Y+ Y+PQQFP QP ++Q + HY SQ V++P++Q N RM+ Sbjct: 1020 ASAAGPPIAATPPAYSTQYVAYSPQQFPNQP-LVQHVPHYQSQHPHVYSPVIQGNARMMA 1078 Query: 827 SGSHPQ-AIVSSSTPQYPSAEQPTPQALYA---------------------TVHQSYPHH 864 +H Q +VSSS QY + EQ A+YA ++ Q Y H Sbjct: 1079 PPTHAQPGLVSSSATQYGAHEQ--THAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHP 1136 Query: 865 ATQLHAH--QPQPATTPTGSQPQSQHA----APSPV---QHQAGQAPHLGSGQPQQNLYH 915 LH H PQP+ TPTG Q QSQH APSPV QHQA QA HL S Q Q +YH Sbjct: 1137 NATLHPHTPHPQPSATPTGQQ-QSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYH 1195 Query: 916 PGALTGTPPSLPPGPSAQSPQSSFP-QPAAVYAIHHQQLPHGFTN---MAHVTQAHVQTG 971 G L TPPS+ P + QSPQ+SFP V+ IH + +TN MAHV QAHVQ+G Sbjct: 1196 AG-LAPTPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSG 1254 Query: 972 ITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHP 1027 + P HP A P +M PP G PQ A+ QS + + ST + +PY+ HP Sbjct: 1255 MV---PSHPTAHAPMMLMTTQPP----GGPQAALAQSALQPIPVSTTAHFPYMTHP 1303 Score = 39.3 bits (90), Expect = 0.020 Identities = 37/134 (27%), Positives = 52/134 (38%), Gaps = 10/134 (7%) Query: 362 GGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKT 421 G + +R G + PPR L +PG A GP MS K Q+ + + Sbjct: 115 GAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQ 174 Query: 422 LSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIP-- 479 + + PPP A P S A+PA + P S+V +SSA+ P Sbjct: 175 QQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPS-----PSSSSVSSSSATAPSS 229 Query: 480 ---VTSSVSDPGVG 490 TS PG+G Sbjct: 230 VVAATSGGGRPGLG 243 Score = 35.4 bits (80), Expect = 0.29 Identities = 45/155 (29%), Positives = 57/155 (36%), Gaps = 14/155 (9%) Query: 343 ASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPR-GPHHLDNSSPGPGSEARGI 401 A+R + L + R RGG ++ G P + PP GP SSP S+ G Sbjct: 22 AARWPGWRSLQRPARRSGRGGG--GAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGS 79 Query: 402 NGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVP--PPPAVGRMYPPRSPKSAAPAPIS 459 NG R L G L P RP +P P A PP +P A+P Sbjct: 80 NGNGGGAFRPGSRRLLG---LGGPP-RPFVVLLLPLASPGA-----PPAAPTRASPLGAR 130 Query: 460 ASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISP 494 AS P + A P P V P S+ P Sbjct: 131 ASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKP 165 Score = 33.9 bits (76), Expect = 0.84 Identities = 34/110 (30%), Positives = 40/110 (36%), Gaps = 20/110 (18%) Query: 21 QAVARRPPGGTSPPNGGLPGPLATSA-APPGP---------PAAASPCLGPVAAAGSGLR 70 Q ARR G G PGP ++A PPGP P +AS C G G R Sbjct: 32 QRPARRSGRGGG---GAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFR 88 Query: 71 RGAEGILAPQPPPPQ-----QHQERPGAAAIGSARGQSTG--KGPPQSPV 113 G+ +L PP PGA R G PP+S V Sbjct: 89 PGSRRLLGLGGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGV 138 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 110 bits (274), Expect = 9e-24 Identities = 181/763 (23%), Positives = 254/763 (33%), Gaps = 119/763 (15%) Query: 345 REGKYIPLPQRVREGPRGGVRCSSSRGGR--PGLSSLPPRGPHHLDNSSPGPGSEARGIN 402 +EG P P ++ P + SS + R P +P P +P P + Sbjct: 897 KEGPATPAP---KQAPALSMTSSSPKKARATPAPKGIPA-SPSPKGAPTP-PAATPPSPK 951 Query: 403 GGPSRMSPK-------AQRPL-RGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAA 454 GGP+ SPK A P +G SP P+ + PP P G P SPK A Sbjct: 952 GGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATP--SPK-GA 1008 Query: 455 PAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEP 514 P P + + P P S A+ P S P + +P SPK S A T + + + P Sbjct: 1009 PTPPAVTPPSP------KGSPAATPFPKGASTP--PAATPPSPKGSPAATPLPKGAPTTP 1060 Query: 515 GRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLD---PFPPRI 571 TL + + G A P P P PP Sbjct: 1061 AATLPSPKGGPATPSLKGAPTPP------------AATPPSPKGGPATPSPKGAPMPPAA 1108 Query: 572 LKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQ 631 PKG GL T G+P + S K P G P PP Sbjct: 1109 TPPSPKG------GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1162 Query: 632 TGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHS 691 +PP KG K P+ K PT P + +P P+ Sbjct: 1163 LATPPP---KGAPTTPAATPPSPKGGLATPSPKG-APTTPAATPPSPKGGLATPSPKGAP 1218 Query: 692 TPSIPVLTAGQSGLYSPQ-------YISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKY 744 T + + GL +P + P GPA P+ P P + + P +G Sbjct: 1219 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGL 1278 Query: 745 RGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQP 804 + PP + + PP + A PP A TP ++ P +P+ PG P P Sbjct: 1279 -----ATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAA-TPPSPKGSPGTP----P 1328 Query: 805 MAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHH 864 P+ P P L + + P + +TP S E PTP A + P H Sbjct: 1329 PKGAPTPPAVTPPSPKGTPTLPA-TTPSSKGGPTTPS--SKEGPTPPA-------ATPSH 1378 Query: 865 ATQLHAHQPQPATTPTGSQPQSQHAAP-----SPVQHQAGQAPHLGSGQPQQNLYHPGAL 919 P P P P+ +P SP + A G+ P + P A+ Sbjct: 1379 KGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAV 1438 Query: 920 TGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPH 979 TP SL P+ +P+ PA + LP A Q +++P Sbjct: 1439 --TPVSLKKAPATSAPKGG---PATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKA 1493 Query: 980 P------GAPHPPQVMLLHP------PQSHGGP------------PQGAVPQSGV--PAL 1013 P GAP P V+ P P S P P P+ + PA+ Sbjct: 1494 PATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAM 1553 Query: 1014 SASTPSPYPYIGHPQGEQPGQAPGFPGGADDRIPPLPPPGELK 1056 + +P P I P+ +AP P + PP P K Sbjct: 1554 TVPSPKKTPAIPTPK-----EAPATPSSKEASSPPAVTPSTYK 1591 Score = 99.0 bits (245), Expect = 2e-20 Identities = 175/749 (23%), Positives = 233/749 (31%), Gaps = 169/749 (22%) Query: 375 GLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMS----PKAQRPLRGAK----TLSSPS 426 G+S P S GP + ++ S + P+ +G+K T SP+ Sbjct: 798 GVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPT 857 Query: 427 NRPSGETSVPPPPAVGRMYPP--RSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSV 484 P P P AV + P P P P + P P G A P + ++ + Sbjct: 858 --PPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTS 915 Query: 485 SDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEE 544 S P +PA I +P+ K T P+ Sbjct: 916 SSPKKARATPAPKGIPASPSP-KGAPTPPAATPPSPK----------------------- 951 Query: 545 LRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVS 604 ++P P PP PKG G T P G+P S Sbjct: 952 ----------GGPATPSPKWAPTPPAATPPSPKG------GPATPSPKGAPTPPAATPPS 995 Query: 605 DKEDKPPLAPSGGTEGPEQPPPPCPSQTGSP-PVGLIKGEDKDEGPVAEQVKKSTLNPNA 663 K +P G P P PS GSP KG K S Sbjct: 996 PKGGPATPSPKGAPTPPAVTP---PSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPL 1052 Query: 664 KEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAV 723 + PT P ++ P +P + TP P T P GPA Sbjct: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAPTP--PAATP--------------PSPKGGPAT 1096 Query: 724 QAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAAT- 782 +P+ P P + + P +G + PP + PA+ PP + A PP A T Sbjct: 1097 PSPKGAPMPPAATPPSPKGGL-----ATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTT 1151 Query: 783 -------PYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPR--MLTSGSHPQA 833 P P+ P PA P P + P + P T S Sbjct: 1152 PAATPPSPKGGLATPPPKGAPTTPAATPPS---PKGGLATPSPKGAPTTPAATPPSPKGG 1208 Query: 834 IVSSS---TPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQ-----PATTPTGSQPQ 885 + + S P P+A P+P+ AT P A A P PAT P P Sbjct: 1209 LATPSPKGAPTTPAATPPSPKGGLAT---PSPKGAPTTPAATPPSPKGGPATPPPKGAPT 1265 Query: 886 SQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAV 945 A P ++ PH G+ P TPPS GP+ P+ + PAA Sbjct: 1266 PPAATPPSLKGGLATPPHKGA---------PNPAVVTPPSPKGGPATSPPKGAPTPPAAT 1316 Query: 946 YAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHP----------PQ 995 P G + PP GAP PP V P P Sbjct: 1317 -----PPSPKG----------------SPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPS 1355 Query: 996 SHGGP----------PQGAVP-QSGVPALSASTPSPYPYIGHPQGE---------QPGQA 1035 S GGP P A P G PA++ +P P I P+G+ P +A Sbjct: 1356 SKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKA 1415 Query: 1036 PGFP----GGA----DDRIPPLPPPGELK 1056 P P G A D PP P LK Sbjct: 1416 PATPVTREGAATPSKGDLTPPAVTPVSLK 1444 Score = 97.1 bits (240), Expect = 8e-20 Identities = 188/775 (24%), Positives = 259/775 (33%), Gaps = 119/775 (15%) Query: 335 SGRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGR--PGLSSLPPRG-----PHHL 387 S + P+ S +G P P P+GG S +G P ++ P+G P Sbjct: 972 SPKGGPATPSPKGAPTP-PAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPK 1030 Query: 388 DNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGET--SVPPPPAVGRMY 445 S+P P + G P+ P A TL SP P+ + P PPA Sbjct: 1031 GASTP-PAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAA---- 1085 Query: 446 PPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTD 505 P SPK P P PP + P+ + P + +P SPK LA Sbjct: 1086 TPPSPKGGPATPSPKGAPMPPAATP-PSPKGGLATPPHKGAPTTPAATPPSPKGGLATPP 1144 Query: 506 VKELSTKEPGRTLEPQE-LA----RIAGKVPGLQNEQKRFQLEELRKFGAQFK---LQPS 557 K T P+ LA + A P + L GA PS Sbjct: 1145 PKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1204 Query: 558 -----SSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPL 612 ++P P P PKG GL T P G+P + S K Sbjct: 1205 PKGGLATPSPKGAPTTPAATPPSPKG------GLATPSPKGAPTTPAATPPSPKGGPATP 1258 Query: 613 APSGGTEGPEQPPPPC------PSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEF 666 P G P PP P G+P ++ GP K + P A Sbjct: 1259 PPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPP 1318 Query: 667 NP-------------TKPLLSVNKSTSTPTSP--------GPRTHST---PSIPVLTAGQ 702 +P T P ++ TPT P GP T S+ P+ P T Sbjct: 1319 SPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSH 1378 Query: 703 SGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGA-----KGSLPPQRSD 757 G P P+ GPA+ +P+ P S +V K A +G+ P + D Sbjct: 1379 KG--GPAMTPPSPK--RGPAIPSPK--GDPTSPAVIPLSPKKAPATPVTREGAATPSKGD 1432 Query: 758 QHQPASAPPMMQAAAAAGPPLVA-ATPYSSYIPYNPQQFPGQPAMMQPMAHYP----SQP 812 PA P ++ A A P ATP S P P P P+ +P A S P Sbjct: 1433 LTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTP--PSPKEPPAPKQVATSSSP 1490 Query: 813 VFAPMLQSNPRMLTSGSHPQAIVSS--STPQYPSAEQPTPQALYATVHQSYPHHATQLHA 870 AP + P + + + P I SS P PS+ + + + P A Sbjct: 1491 KKAP---ATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEA 1547 Query: 871 HQPQPATTP----TGSQPQSQHAAPSPVQHQAGQAP------HLGSGQPQQNLYHPGALT 920 P T P T + P + A +P +A P + G+ P++ L P A+T Sbjct: 1548 LIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPP-AVT 1606 Query: 921 GTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHP 980 P P P A +P S PA P G VT + ++ T+ Sbjct: 1607 SPSPKEAPTPPAVTPPSPEKGPAT-------PAPKGTPTSPPVTPSSLKDSPTS------ 1653 Query: 981 GAPHPPQV---MLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQP 1032 P V M PQ+ G P P + L A P P I P + P Sbjct: 1654 ----PASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGP 1704 Score = 88.2 bits (217), Expect = 4e-17 Identities = 168/704 (23%), Positives = 236/704 (33%), Gaps = 110/704 (15%) Query: 391 SPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGE---TSVPPPPAVGRMYPP 447 S P A G S + A L G +L+ P N P E T++P P P Sbjct: 652 SADPAGVAPTTAKGTSTYTTTASPFLEGTVSLA-PKNHPVKEGTLTTLPLVPTASENCPV 710 Query: 448 RSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAP--TD 505 AP++ P I +VP S S+P + PG + S +LAP + Sbjct: 711 APSPQNTCAPLATLVLAPEIPKSVP--SPSLPPAGT--PPGTKKVDGISHTSALAPVASS 766 Query: 506 VKELSTKEPGRTLEPQE---LARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN 562 KE T++ G + L +A L K G+ P + + Sbjct: 767 PKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSS 826 Query: 563 SLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPE 622 + P L E + D T+ SP + PL+P G T P+ Sbjct: 827 PVSPVEASFLPENSLSFQGSKDSPATTH---SPTPPSPKGAPTPSAVTPLSPKGVTLPPK 883 Query: 623 QPPPPCPSQTGSPPVGLIKGEDKDEGPVA---EQVKKSTLNPNAKEFN--------PTKP 671 + P P P G K ++ KK+ P K PT P Sbjct: 884 ETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPP 943 Query: 672 LLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQY-------ISYIPQIHMGPAVQ 724 + P +P P+ TP + + G +P + P GPA Sbjct: 944 AATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATP 1003 Query: 725 APQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGP-PLVAATP 783 +P+ P P + + P +G+ + P + PA+ PP + + AA P P A T Sbjct: 1004 SPKGAPTPPAVTPPSP----KGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTT 1059 Query: 784 YSSYIPYNPQQFPGQPAMM---QPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840 ++ +P +P+ P P++ P A P P P S P Sbjct: 1060 PAATLP-SPKGGPATPSLKGAPTPPAATPPSPKGGPATPS---------------PKGAP 1103 Query: 841 QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900 P+A P+P+ AT PH TTP + P + +P A Sbjct: 1104 MPPAATPPSPKGGLATP----PHKGAP---------TTPAATPPSPKGGLATPPPKGAPT 1150 Query: 901 APHLGSGQPQQNLYHP---GALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGF 957 P P+ L P GA T TP + PP SP+ P+ P G Sbjct: 1151 TPAATPPSPKGGLATPPPKGAPT-TPAATPP-----SPKGGLATPS----------PKGA 1194 Query: 958 TNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQ-SGVPALSAS 1016 T + G+ A P GAP P PP GG A P G P A+ Sbjct: 1195 PTTPAATPPSPKGGL--ATPSPKGAPTTPAAT---PPSPKGGL---ATPSPKGAPTTPAA 1246 Query: 1017 TPSPYPYIGHPQGEQPGQAPGFPGGADDRIPPLPPPGELKIVLA 1060 TP P P G P P AP PP P LK LA Sbjct: 1247 TP-PSPK-GGPATPPPKGAP---------TPPAATPPSLKGGLA 1279 Score = 58.2 bits (139), Expect = 4e-08 Identities = 161/716 (22%), Positives = 222/716 (31%), Gaps = 142/716 (19%) Query: 417 RGAKTLSSPSNRPSGETSVPPPPAVG---RMYPPRSPKSAAPAPISASCPEPPIGS---- 469 +G T+SS + PSG +V ++ + SP + P+ A P +G+ Sbjct: 383 KGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLV 442 Query: 470 --------AVPTSSASIP--VTSSVSDPGVGSISPASPK-ISLAPTDVKELSTKEPGRTL 518 A PT++ + V+ +S + +I P SP + +AP KE ST + TL Sbjct: 443 VTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPST-QVATTL 501 Query: 519 ---------EPQELARIAGKVPGLQNEQKRFQLEELRKFGAQF---------KLQPS--- 557 +P++L + V QK Q GA F K P+ Sbjct: 502 RIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLP 561 Query: 558 ---SSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPM--GSPVSSKTESVSDKEDKPPL 612 ++P+NS E P E + EP+ G P SS T + + Sbjct: 562 LVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLG-VNSSASV 620 Query: 613 APSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTL------------- 659 + GP+ P S +P V E D VA K T Sbjct: 621 IKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGT 680 Query: 660 ------NPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISY 713 N KE T L S + P +P P+ P ++ A P+ Sbjct: 681 VSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLA-------PEIPKS 733 Query: 714 IPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAA 773 +P + PA P S + P + S AS+ + A Sbjct: 734 VPSPSLPPAGTPPGTKKVD-GISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLAD 792 Query: 774 AGPPL-VAATPYSSYIPYNPQQFPGQPAMMQPMAHY--PSQPVFAPMLQSNPRMLTSGSH 830 + PL V+ +P + P G P+ + P PV A L N Sbjct: 793 SPSPLGVSVSPQTK----RPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKD 848 Query: 831 PQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAA 890 A S TP P PTP A V P T P TPT S Sbjct: 849 SPATTHSPTPPSPKGA-PTPSA----VTPLSPKGVTL------PPKETPTPSVVNLPFPK 897 Query: 891 PSPVQHQAGQAPHLG--SGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAI 948 P QAP L S P++ T P +P PS Sbjct: 898 EGPATPAPKQAPALSMTSSSPKK-----ARATPAPKGIPASPS----------------- 935 Query: 949 HHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQS 1008 P G AP P P P+ P P A P S Sbjct: 936 -----PKG------------------APTPPAATPPSPKGGPATPSPKWAPTPPAATPPS 972 Query: 1009 --GVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRIPPLPPPGELKIVLAAT 1062 G PA + +P P P + G A P GA PP P K AAT Sbjct: 973 PKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAP--TPPAVTPPSPKGSPAAT 1026 Score = 41.2 bits (95), Expect = 0.005 Identities = 78/327 (23%), Positives = 115/327 (35%), Gaps = 63/327 (19%) Query: 381 PRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA 440 P P + SSP P G PS PK + + A T SP P+ PP P Sbjct: 1571 PATPSSKEASSP-PAVTPSTYKGAPS---PK-ELLIPPAVTSPSPKEAPTPPAVTPPSPE 1625 Query: 441 VGRMYP---------PRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGS 491 G P P +P S +P S + +G+ VP +S +P + Sbjct: 1626 KGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVL 1685 Query: 492 ISPA--SPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFG 549 ++PA S I APT K TK+ T P P +N K Sbjct: 1686 VAPAPESTPIITAPTR-KGPQTKKSSATSPP------ICPDPSAKNGSK----------- 1727 Query: 550 AQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDK 609 P +++ P P ++++ K D + + +P SK + Sbjct: 1728 ---------GPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKAST------- 1771 Query: 610 PPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPT 669 PL + + +P S SPPV L P+A + P ++F P+ Sbjct: 1772 -PLTAAAFEKVLPKPESASVSAAPSPPVSL---------PLAPSPVPTL--PPKQQFLPS 1819 Query: 670 KPLLSVNKSTSTPTSPGPRTHSTPSIP 696 P L V +S S P +P P IP Sbjct: 1820 SPGL-VLESPSKPLAPADEDELLPLIP 1845 Score = 40.0 bits (92), Expect = 0.012 Identities = 136/646 (21%), Positives = 210/646 (32%), Gaps = 101/646 (15%) Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPP----------PAVGRMYPPRSPKSAA 454 P + A P+ A ++++ +P ++PPP A + P SP + A Sbjct: 17 PQPQAETAVLPMSSALSVTAALGQPG--PTLPPPCSPAPQQCPLSAANQASPFPSPSTIA 74 Query: 455 PAPISASCPEPPIGSAVPTSSAS--------------IPVTSSVSDP-------GVGSIS 493 P+ P+ G+A+P +A P +++ P G S S Sbjct: 75 STPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSS 134 Query: 494 PASPKISLAPTDVKELSTKEPGRTLEPQELA------RIAGKVPGLQNEQKRFQLEELRK 547 ++LAP V++ S P P +A I P +E K L K Sbjct: 135 APLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPK----TNLNK 190 Query: 548 FGAQFKLQPSSSPENSLDPFPPRILKEEP---KGKEKEVDGLLTSEPMGSPVSS------ 598 ++ P +P PP I+ P + + S P +P ++ Sbjct: 191 VPSEVVPNPKGTPS------PPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASP 244 Query: 599 --KTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKK 656 K ++S P S +GP PP T S PV + K GP Sbjct: 245 QVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPV--VTSSQKTAGPNTPPDFP 302 Query: 657 STLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQS--GLYSPQYISYI 714 +L + + S S GP S P++ ++ S G P S I Sbjct: 303 ISLGSHLAPLHQ-----SSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVI 357 Query: 715 PQI----HMGPAVQAPQMYPYPVSNSVPGQQGKYR-GAKGSLPPQRSDQHQPASAPPMMQ 769 P + + PA A P + P GSL S P ++ + Sbjct: 358 PPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKS 417 Query: 770 AA-AAAGPPLVAATPYSS-----YIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPR 823 + A PLVA P SS + NP P +A S P + S P Sbjct: 418 SPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPP-----MSSGPI 472 Query: 824 MLTSGSHPQAIVSSS-TPQYPSAEQPTPQALYATVHQSYPHHATQLHAH--QPQPATTPT 880 + P A+V + P+ PS + T + + P L + P Sbjct: 473 SNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDL 532 Query: 881 GSQPQSQHAAP-SPVQHQAGQAPH-------LGSGQPQQNLYHPGALTGTPPSLPPGPSA 932 + P S AP SP QAG L P+ + T + P +P P A Sbjct: 533 QTVPASLEGAPFSPA--QAGLTTKKDPTVLPLVQAAPKNSPSFQS--TSSSPEIPLSPEA 588 Query: 933 QSPQSSFPQPAAV-YAIHHQQLPHGFTNMAHVTQAHVQTGITAAPP 977 + S +P + P G + A V + G +A P Sbjct: 589 TLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGP 634 Score = 39.7 bits (91), Expect = 0.015 Identities = 35/122 (28%), Positives = 48/122 (39%), Gaps = 9/122 (7%) Query: 4 PQPLQQPSQPQQPPPTQQA--VARRPPGGTSPPNGGLPGPLATSAAPPGP-----PAAAS 56 P P P+ P PP+ + P G +PP P P + AA P P P AA+ Sbjct: 980 PSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAAT 1039 Query: 57 PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPG--AAAIGSARGQSTGKGPPQSPVF 114 P + A + L +GA A P P+ P A A + KG P +P Sbjct: 1040 PPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP 1099 Query: 115 EG 116 +G Sbjct: 1100 KG 1101 Score = 39.7 bits (91), Expect = 0.015 Identities = 39/124 (31%), Positives = 46/124 (37%), Gaps = 22/124 (17%) Query: 4 PQPLQQPSQPQQPPPTQQAVARRPPGG--TSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61 P P P+ P PP+ P GG T PP G P AT +P G A SP P Sbjct: 1143 PPPKGAPTTPAATPPS-------PKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAP 1195 Query: 62 VAAAGS------GLR----RGAEGILAPQPPPPQQHQERP---GAAAIGSARGQSTGKGP 108 A + GL +GA A PP P+ P GA +A S GP Sbjct: 1196 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGP 1255 Query: 109 PQSP 112 P Sbjct: 1256 ATPP 1259 Score = 39.7 bits (91), Expect = 0.015 Identities = 31/112 (27%), Positives = 39/112 (34%), Gaps = 6/112 (5%) Query: 3 KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPV 62 K P P + PP + + GT PP G P T +P G P P P Sbjct: 1298 KGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTL--PATTPS 1355 Query: 63 AAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQS--TGKGPPQSP 112 + G EG P P H+ P RG + + KG P SP Sbjct: 1356 SKGGPTTPSSKEGPTPPAATP--SHKGGPAMTPPSPKRGPAIPSPKGDPTSP 1405 Score = 38.5 bits (88), Expect = 0.034 Identities = 35/116 (30%), Positives = 44/116 (37%), Gaps = 14/116 (12%) Query: 4 PQPLQQPSQPQQPPPTQQAVARRPP--GGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61 P P P P PP+ + PP G + P P P A PP A +P P Sbjct: 1097 PSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1156 Query: 62 VAAAGSGLR----RGAEGILAPQPPPPQQHQERPGAAAIGSARG-QSTGKGPPQSP 112 + G GL +GA A PP P+ G A S +G +T P SP Sbjct: 1157 PSPKG-GLATPPPKGAPTTPAATPPSPK------GGLATPSPKGAPTTPAATPPSP 1205 Score = 38.5 bits (88), Expect = 0.034 Identities = 34/113 (30%), Positives = 47/113 (41%), Gaps = 11/113 (9%) Query: 4 PQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGP-LATSAAPPGPPAAASPCLGPV 62 P P P+ P PP+ + G +PP+ G P P + T +P G PA + P P Sbjct: 1258 PPPKGAPTPPAATPPSLKG------GLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPT 1311 Query: 63 -AAAGSGLRRGAEGILAPQ--PPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112 AA +G+ G P+ P PP P A S+ KG P +P Sbjct: 1312 PPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSS-KGGPTTP 1363 Score = 36.6 bits (83), Expect = 0.13 Identities = 35/119 (29%), Positives = 42/119 (35%), Gaps = 19/119 (15%) Query: 4 PQPLQQPSQPQQPPPTQQA--VARRPPGGTSPPNGGLPGPLATSAAP-----PGPPAAA- 55 P P P+ P PP+ + P +PP P P A P P PPAA Sbjct: 934 PSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATP 993 Query: 56 -SPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQST-GKGPPQSP 112 SP GP + G AP PP + AA +G ST P SP Sbjct: 994 PSPKGGPATPSPKG---------APTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSP 1043 Score = 36.6 bits (83), Expect = 0.13 Identities = 34/119 (28%), Positives = 41/119 (34%), Gaps = 19/119 (15%) Query: 4 PQPLQQPSQPQQPPPTQQ---AVARRPPGGTSPPNGGLPGPLATSAAP-----PGPPAAA 55 P P + P PP+ + A P G + P LP P A P P PPAA Sbjct: 1027 PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAAT 1086 Query: 56 --SPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112 SP GP + G AP PP + G A +T P SP Sbjct: 1087 PPSPKGGPATPSPKG---------APMPPAATPPSPKGGLATPPHKGAPTTPAATPPSP 1136 Score = 36.6 bits (83), Expect = 0.13 Identities = 33/121 (27%), Positives = 43/121 (35%), Gaps = 9/121 (7%) Query: 4 PQPLQQPSQPQQPPPTQQA--VARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61 P P P+ P PP+ + P G + P P P A PP A P P Sbjct: 1212 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP 1271 Query: 62 VAAAGSGL----RRGAEGILAPQPPPPQ--QHQERPGAAAIGSARGQSTGKGPPQSPVFE 115 + G GL +GA PP P+ P A A + KG P +P + Sbjct: 1272 PSLKG-GLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPK 1330 Query: 116 G 116 G Sbjct: 1331 G 1331 Score = 36.2 bits (82), Expect = 0.17 Identities = 27/105 (25%), Positives = 36/105 (34%), Gaps = 9/105 (8%) Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAA 65 P P PPP A PP T P G P AT+ + G P S GP A Sbjct: 1317 PPSPKGSPGTPPPKG---APTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPA 1373 Query: 66 GSGLRRGAEGILAPQP------PPPQQHQERPGAAAIGSARGQST 104 + +G + P P P P+ P + + +T Sbjct: 1374 ATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPAT 1418 Score = 35.0 bits (79), Expect = 0.38 Identities = 37/125 (29%), Positives = 45/125 (36%), Gaps = 24/125 (19%) Query: 4 PQPLQQP------SQPQQ----PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAP----- 48 P P Q P S P++ P P + P G +PP P P A P Sbjct: 903 PAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWA 962 Query: 49 PGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKG- 107 P PPAA P P + +GA A PP P+ G A S +G T Sbjct: 963 PTPPAATPP--SPKGGPATPSPKGAPTPPAATPPSPK------GGPATPSPKGAPTPPAV 1014 Query: 108 PPQSP 112 P SP Sbjct: 1015 TPPSP 1019 Score = 35.0 bits (79), Expect = 0.38 Identities = 34/120 (28%), Positives = 43/120 (35%), Gaps = 18/120 (15%) Query: 10 PSQPQQPPPTQQA--VARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGS 67 P+ P PP+ + P G PP P P A PP A +P P + G Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG- 1138 Query: 68 GLR----RGAEGILAPQP---------PPPQQHQERPGAAAIGSARGQST--GKGPPQSP 112 GL +GA A P PPP+ P A G +T KG P +P Sbjct: 1139 GLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1198 Score = 35.0 bits (79), Expect = 0.38 Identities = 28/121 (23%), Positives = 43/121 (35%), Gaps = 7/121 (5%) Query: 4 PQPLQQPSQPQQPPPTQQAVARRP---PGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 P P P+ P P + + P G +P G L P T + PA ++P G Sbjct: 1396 PSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGG 1455 Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120 P + +G + A PP P++ A S + P +P V + Sbjct: 1456 PATPSS----KGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPS 1511 Query: 121 S 121 S Sbjct: 1512 S 1512 Score = 34.7 bits (78), Expect = 0.49 Identities = 67/286 (23%), Positives = 105/286 (36%), Gaps = 44/286 (15%) Query: 796 PGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQAL-Y 854 PG+ P Q + P ++ ++S A + P P P PQ Sbjct: 2 PGEATETVPATE---QELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPL 58 Query: 855 ATVHQSYPHHA------TQLHAHQPQPAT---TPTGSQPQSQHAAPSPVQHQAGQAPHLG 905 + +Q+ P + T L PQ ++ P G+ P++ P+ + A L Sbjct: 59 SAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAA-LA 117 Query: 906 SGQPQQNLYHPGALTGTPPSLPP------GPSAQSPQSSFP-----QPAAVYAIHHQQLP 954 P + P L GTP S P P + S+FP P +V + Sbjct: 118 LASP---MIAP-TLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSV- 172 Query: 955 HGFTNMAHVTQAHVQTGITAAPP---PHP-GAPHPPQVMLLHPPQSHGGPPQGAVPQSGV 1010 T A + + +T + P P+P G P PP ++ P H P ++ QSGV Sbjct: 173 --ITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVP--YHCVTPMASI-QSGV 227 Query: 1011 PALSASTPSPYPYIGHPQGEQPG-----QAPGFPGGADDRIPPLPP 1051 +L +TP+ I PQ + +P PG + P PP Sbjct: 228 ASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPP 273 Score = 34.7 bits (78), Expect = 0.49 Identities = 32/127 (25%), Positives = 41/127 (32%), Gaps = 20/127 (15%) Query: 4 PQPLQQPSQPQQPPPTQQA--VARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61 P P P+ P PP+ + P G + P P P A P A +P P Sbjct: 1189 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1248 Query: 62 VAAAGSGLRRGAEGILAPQPP-------------PPQQHQERPGAAAIGSARG---QSTG 105 + G +G AP PP PP + P S +G S Sbjct: 1249 PSPKGGPATPPPKG--APTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPP 1306 Query: 106 KGPPQSP 112 KG P P Sbjct: 1307 KGAPTPP 1313 Score = 32.0 bits (71), Expect = 3.2 Identities = 25/98 (25%), Positives = 34/98 (34%), Gaps = 6/98 (6%) Query: 16 PPPTQQAVARRPP-GGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAE 74 PP + A PP G +PP P P + PP A P + P + G+ Sbjct: 1294 PPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATT 1353 Query: 75 GILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112 P P + AA S +G GP +P Sbjct: 1354 PSSKGGPTTPSSKEGPTPPAATPSHKG-----GPAMTP 1386 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 104 bits (260), Expect = 4e-22 Identities = 199/800 (24%), Positives = 279/800 (34%), Gaps = 133/800 (16%) Query: 357 REGP-RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRP 415 R GP R S + RP S R P N+SPGP S G G +R P Q+ Sbjct: 76 RAGPTRSAGTSSRNPASRPPASGRGERAPP-AKNTSPGPVSSP-GRASGTTRPGPLGQKG 133 Query: 416 LR---------GAKT-------LSSPSNRP-SGETSVPPPPAVGRMYPPRSPKSAAPAPI 458 LR G T LS+ + R SG T P PA+ R + P P Sbjct: 134 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 193 Query: 459 SASCPEPPI-GSAVPTSSASIPVTSSVS-------DPGVGSISPASPKISLAPTDVKELS 510 ++ P PP G SSAS T+ S G G PAS +S + T + + Sbjct: 194 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253 Query: 511 TKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQF-----------------K 553 P P+ A + P + Q+ RK A K Sbjct: 254 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTK 313 Query: 554 LQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLA 613 +P P+N+ P P + P L T P+ P S S+ P Sbjct: 314 ARPVPPPDNAATPLPATLPPSPP---------LATPLPLAPPSPSAPPSLQTLPSPPATP 364 Query: 614 PSGGTEGPEQPPPPCPSQTGS-PPVGLIKGEDKDE-----GPVAEQVKKSTLNPNAKEFN 667 PS PP P + PP+ + P+A ++T + + Sbjct: 365 PSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQ 424 Query: 668 PTKPLLSVN--KSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQA 725 T L+++ ++ ++ TSP + P P L A S SP Q + PAV Sbjct: 425 ATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPL-----QTSLSPAVSP 479 Query: 726 PQ----MYPYPVSNSVPGQQGKYRGAKGSLPPQRSD--------QHQPAS--APPMMQAA 771 ++P +S+ + + +PP + Q PAS PP+ Sbjct: 480 LSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLP 539 Query: 772 AAAGPPLVAA-----TPYSSYIPYN---PQQFPGQPAMMQPMAHYPSQ----PVFAPMLQ 819 + A PPL A TP+ P P Q P P + P PS P AP Sbjct: 540 SLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSP-LTTPPPETPSSIATPPPQAPPAL 598 Query: 820 SNPRMLTSGSHPQAIVSSSTPQYP------------SAEQPTPQALYATVHQSYPHHATQ 867 ++P + S P + +++ PQ P S P + AT P+ A Sbjct: 599 ASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPN-ALA 657 Query: 868 LHAHQP--QPATTPTGSQPQSQHAAP--SPVQHQAGQAPHLGSGQPQQNLYHPGALTGTP 923 +H Q P +P P S A+P SP QAP + P Q + +P Sbjct: 658 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ-------VPPSP 710 Query: 924 PSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPH--PG 981 P+ PP + +P P P A + P M+ +A PPP P Sbjct: 711 PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSP----------SATPPPRVPPL 760 Query: 982 APHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGG 1041 PP + PP S P P PAL+ TP P + P PGQAP P Sbjct: 761 LAAPPLQVPPSPPASLPMSPLAKPPPQAPPALA--TP-PLQALPSPPASFPGQAPFSPSA 817 Query: 1042 ADDRIPPLPPPGELKIVLAA 1061 + P PP + VLAA Sbjct: 818 SLPMSPLATPPPQAPPVLAA 837 Score = 79.0 bits (193), Expect = 2e-14 Identities = 160/670 (23%), Positives = 225/670 (33%), Gaps = 102/670 (15%) Query: 440 AVGRMYPPRSPKSAAPAPISASCPEPPIGSA---VPTSSASI---PVTSSVSDPGVGSIS 493 A R R+P P P + P PP+ A V ++ ++ P+ G +I Sbjct: 12 AAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71 Query: 494 PASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFK 553 ++P+ PT S++ P P R + P +N Sbjct: 72 ESAPR--AGPTRSAGTSSRNPAS--RPPASGR-GERAPPAKNTSP--------------- 111 Query: 554 LQPSSSPENSLDPFPPRILKEEP---KGKEKEVDGLLTSEPMGSPVSS----KTESVSDK 606 P SSP + P L ++ +E G T P S +S+ T + Sbjct: 112 -GPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG 170 Query: 607 EDKPPLAPSGGTEGPEQP-PPPCPSQTGSPPVGLIKGEDKDEGP---VAEQVKKSTLNPN 662 P +A G E P P PS PP EGP V+ + ST P+ Sbjct: 171 TPSPAMARRSRAAGTEVGLPRPAPSARPRPPT---------EGPRKSVSSASEHSTTEPS 221 Query: 663 -AKEFNP----------TKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTA-----GQSGLY 706 A P ++ L S S+P GP TP P + G L Sbjct: 222 PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR 281 Query: 707 SPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPP 766 PQ P+ PA+ P + P G A+ PP + PA+ PP Sbjct: 282 PPQVTP--PRKDAAPALGPLSSSPL----ATPSPSG--TKARPVPPPDNAATPLPATLPP 333 Query: 767 MMQAAA--AAGPPLVAATPYSSYIPYNPQQFPGQ--PAMMQPMAHYPSQPVFAPMLQSNP 822 A PP +A P +P P P Q P+M P P P +Q P Sbjct: 334 SPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQV-P 392 Query: 823 RMLTSGS---HPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTP 879 LTS S P + SS S PT QA ++ + S P +PA+TP Sbjct: 393 HSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMS-PRQTQASLTSPSRPASTP 451 Query: 880 TGSQP-QSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGP-------- 930 S P Q+ + P+ Q +P + ++ AL+ P P Sbjct: 452 PDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPP 511 Query: 931 ----SAQSPQSSFPQPAAVYAIHHQQLPHGF-----TNMAHVTQAHVQTGITAAPPPHPG 981 S+ +P S PA++ + LP T A +T H++T AP P Sbjct: 512 LETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQA 571 Query: 982 APHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGG 1041 P P P S PP A P P L P + P P QAP Sbjct: 572 PPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATP----PPQAPPXLAL 627 Query: 1042 ADDRIPPLPP 1051 + PP PP Sbjct: 628 PPLQAPPSPP 637 Score = 47.0 bits (110), Expect = 1e-04 Identities = 72/304 (23%), Positives = 108/304 (35%), Gaps = 34/304 (11%) Query: 374 PGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSR-----MSPKAQRPLRGAKTLSSPSNR 428 P + PP P P A + PS MSP A P R L++P + Sbjct: 708 PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQ 767 Query: 429 --PSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPI---GSAVPTSSASIPVTSS 483 PS S+P P PP++P + A P+ A P PP G A + SAS+P++ Sbjct: 768 VPPSPPASLPMSPLAKP--PPQAPPALATPPLQA-LPSPPASFPGQAPFSPSASLPMSPL 824 Query: 484 VSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGK------VPGLQNEQ 537 + P A+P + + P+ + + P R P ++G PG Sbjct: 825 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 884 Query: 538 KRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVS 597 R L P + +S P L+ G E G S P + ++ Sbjct: 885 SRSPSSTLS--------GPDLAGHSSSATSTPEELRGYDSGPE---GGAAASPPPDAELA 933 Query: 598 SKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKS 657 + + + PPLA G P P P TG + + EGP + Sbjct: 934 ACHPAAWSRGPAPPLA----FRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG 989 Query: 658 TLNP 661 L+P Sbjct: 990 ALDP 993 Score = 46.2 bits (108), Expect = 2e-04 Identities = 43/134 (32%), Positives = 51/134 (38%), Gaps = 30/134 (22%) Query: 4 PQPLQQPSQP--QQPPPTQQAVA----RRPPGGTSPPNGGLP----GPLATS-------- 45 P PLQ P P PP T ++A + PP SPP GLP PLAT Sbjct: 566 PCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXL 625 Query: 46 -----AAPPGPPAAASPCLGPVAAAGSGLRRG-----AEGILAPQPPPPQQHQERPGAAA 95 APP PP ASP L P+A + +P P PP Q P A+ Sbjct: 626 ALPPLQAPPSPP--ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 683 Query: 96 IGSARGQSTGKGPP 109 S + PP Sbjct: 684 PVSPSATPPSQAPP 697 Score = 37.7 bits (86), Expect = 0.058 Identities = 33/123 (26%), Positives = 43/123 (34%), Gaps = 18/123 (14%) Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTS------------PPNGGLPGPLATSAAPPGPPA 53 PLQ P P PP P + PP+ + P + A+PP P+ Sbjct: 629 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 688 Query: 54 AASPCLGPVAAAGSGLR----RGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109 A P P + A L+ A ++P PP Q P AA S PP Sbjct: 689 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP--QAPPPLAAPPLQVPPSPPASPP 746 Query: 110 QSP 112 SP Sbjct: 747 MSP 749 Score = 37.0 bits (84), Expect = 0.099 Identities = 39/122 (31%), Positives = 48/122 (39%), Gaps = 30/122 (24%) Query: 13 PQQPP--PTQQAVARRPPGGTSPPNGGLPGP---LATSAAPPGPP--AAASPCLGPVAAA 65 P PP PT QA RRPP T P+ + GP LA + PP PP + +S GP A Sbjct: 843 PPSPPASPTLQA-PRRPP--TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 899 Query: 66 GS-----------GLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVF 114 S G G EG A PPP A + + + +GP F Sbjct: 900 HSSSATSTPEELRGYDSGPEGGAAASPPPD---------AELAACHPAAWSRGPAPPLAF 950 Query: 115 EG 116 G Sbjct: 951 RG 952 Score = 36.2 bits (82), Expect = 0.17 Identities = 34/112 (30%), Positives = 43/112 (38%), Gaps = 6/112 (5%) Query: 3 KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAP-PGPPAAASPCLGP 61 KP+ LQ PQ PP + A P +SP P P T A P P P AA+P P Sbjct: 273 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPL--ATPSPSGTKARPVPPPDNAATPL--P 328 Query: 62 VAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP-QSP 112 S + P P P Q P A ++ + PP Q+P Sbjct: 329 ATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAP 380 Score = 33.5 bits (75), Expect = 1.1 Identities = 32/113 (28%), Positives = 39/113 (34%), Gaps = 24/113 (21%) Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLP--GPLATSAAPPGPPAAASPCL 59 L PLQ P P PP + PP PP P P + A+PP P+A P Sbjct: 699 LAAPPLQVPPSPPASPPMSPSAT--PPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPR 756 Query: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112 P A L+ + P PP S K PPQ+P Sbjct: 757 VPPLLAAPPLQ------VPPSPP--------------ASLPMSPLAKPPPQAP 789 Score = 32.3 bits (72), Expect = 2.4 Identities = 38/130 (29%), Positives = 48/130 (36%), Gaps = 22/130 (16%) Query: 2 LKPQPLQQPSQPQQPPPTQQAVA---RRPPGGTSPPNGGLPGPLATS-----AAPP--GP 51 L PLQ P P PP + R PP +PP P P A+ A PP P Sbjct: 730 LAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAP 789 Query: 52 PAAASPCL-----GPVAAAGSG-LRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTG 105 PA A+P L P + G A ++P PP P A + +A Sbjct: 790 PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP------PQAPPVLAAPLLQVP 843 Query: 106 KGPPQSPVFE 115 PP SP + Sbjct: 844 PSPPASPTLQ 853 Score = 31.6 bits (70), Expect = 4.2 Identities = 29/91 (31%), Positives = 34/91 (37%), Gaps = 13/91 (14%) Query: 16 PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEG 75 PPP + A P + P PLA AP G P P GP +A G EG Sbjct: 926 PPPDAELAACHPAAWSRGP----APPLAFRGAP-GAPLPWPPATGPGSADGLCTIYETEG 980 Query: 76 ILAPQPPPPQQHQERPGAAAIGSARGQSTGK 106 P+ PGA G + G S GK Sbjct: 981 --------PESATPAPGALDPGPSPGTSGGK 1003 Score = 30.4 bits (67), Expect = 9.2 Identities = 20/73 (27%), Positives = 29/73 (39%), Gaps = 2/73 (2%) Query: 11 SQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLR 70 S P + P+ + R P + P GL PP AA P LGP++++ Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA--PALGPLSSSPLATP 307 Query: 71 RGAEGILAPQPPP 83 + P PPP Sbjct: 308 SPSGTKARPVPPP 320 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 98.2 bits (243), Expect = 4e-20 Identities = 178/751 (23%), Positives = 253/751 (33%), Gaps = 128/751 (17%) Query: 381 PRGPH--HLDNSSPGP-GSEARGINGGPSRMSPKAQRPLRGAKTL-----SSPSNRPSGE 432 P+G H + PGP EA+ + ++ P+ + PL L SP + P E Sbjct: 396 PKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEE 455 Query: 433 TSVPPPPAVGRMYPPRSPKSAAPAP----ISASCPEPPIGSAVPTSSASIPVTSSVSDPG 488 + PPP R+ PP A+P P +S E P+ S S P SS P Sbjct: 456 SPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSP- 514 Query: 489 VGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKF 548 SP SP P+ E P E L+ P + EEL Sbjct: 515 -LEESPLSPPEESPPSPALETPLSPPP---EASPLS------PPFEESPLSPPPEELPTS 564 Query: 549 GAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGL--------LTSEPMGSPVSSKT 600 + S PE S PP +E P E L L+ P SP+S Sbjct: 565 PPPEASRLSPPPEESPMSPPP---EESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPP 621 Query: 601 ES--VSDKEDKPPLAPSGGTEGPEQPPP--------PCPSQTGSPPVGLIKGEDKDEGPV 650 E+ +S + P++P E P PPP P S+ PP +E P Sbjct: 622 EASRLSPPPEDSPMSPP-PEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPT 680 Query: 651 AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGL-YSPQ 709 + + S L+P E +PT P +P SP P S S+P+ + L PQ Sbjct: 681 SPPPEASRLSP-PPEDSPTSP-----PPEDSPASPPPE-DSLMSLPLEESPLLPLPEEPQ 733 Query: 710 YISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQH-QPASAPPMM 768 H+ P + P + P P + L PQ + H P P + Sbjct: 734 LCPRSEGPHLSPRPEEPHLSPRP--------------EEPHLSPQAEEPHLSPQPEEPCL 779 Query: 769 QAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQP-MAHYPSQPVFAPMLQS------- 820 A P ++ ++ P++ P +P ++ P +P +P + Sbjct: 780 --CAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQS 837 Query: 821 -----NPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQP 875 +PR S P+ P P E+P + + P L +P Sbjct: 838 EEPCLSPRPEESHLSPEL---EKPPLSPRPEKPPEEPGQCPAPEELP-----LFPPPGEP 889 Query: 876 ATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQP--QQNLYHPGALTGTPPSLPP----- 928 + +P +P P+ + P SG+P L P L PP L P Sbjct: 890 SLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPL---PPPLSPIITAA 946 Query: 929 GPSAQSPQSSFPQPAAVYAIHHQQLPHGF----TNMAHVTQAHVQTGITAAP---PPHPG 981 P A SP P + P T ++ +A+ P PP PG Sbjct: 947 APPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPG 1006 Query: 982 APHPPQVMLLH---PPQ-----SHGGPPQGAVP-QSGVPALSASTPSPYPYIG------- 1025 +P P +L PPQ H PQ + P Q PAL S PSP IG Sbjct: 1007 SPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSD 1066 Query: 1026 ----HPQGEQPGQAPGFPGGADDRIPPLPPP 1052 H + P P PLP P Sbjct: 1067 EAELHEMETEKVSEPECPALEPSATSPLPSP 1097 Score = 55.1 bits (131), Expect = 4e-07 Identities = 141/594 (23%), Positives = 202/594 (34%), Gaps = 98/594 (16%) Query: 422 LSSPSNRPSGETSVPPPP-AVGRMYPPRSP-----KSAAPAPISASCP---EPPIGSAVP 472 ++ ++RP+ +PP P A+G P +P PA +S S +PP GS Sbjct: 2093 IARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPG 2152 Query: 473 TSSAS---------IPVTSSVSDP-GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQE 522 S +P DP G+ P P+ AP + G +P Sbjct: 2153 PDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPT-GAPAQPPM 2211 Query: 523 LARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRI----LKEEPK- 577 L A PG Q E S+P+ L P P + + E P Sbjct: 2212 LG--ASSRPGAG------QPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGV 2263 Query: 578 GKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPV 637 G K + LL+ P G S K V KE+ +PS G PP SP Sbjct: 2264 GGGKASEPLLSPPPFGE--SRKALEVK-KEELGASSPSYG--------PPNLGFVDSPSS 2312 Query: 638 GLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPV 697 G G + + P V K+ L P A + P P L + P P P PS P Sbjct: 2313 GTHLGGLELKTP---DVFKAPLTPRASQVEPQSPGLGLR-----PQEPPPAQALAPSPP- 2363 Query: 698 LTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQ---GKYRGAKGSLPPQ 754 ++ P SY P PQ P ++P + + S P Sbjct: 2364 ---SHPDIFRPG--SYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPAS-PQS 2417 Query: 755 RSDQHQPASAPPMMQAAAAAGPPLVAATP-YSSYIPYNPQQFPGQPAMMQPMA--HYPSQ 811 +S P + P+ A P TP + S PY+ P +P P A H P + Sbjct: 2418 QSSSQSPLTPRPLSAEAFCPSP----VTPRFQSPDPYSRP--PSRPQSRDPFAPLHKPPR 2471 Query: 812 PVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAE--------QPTPQALYATVHQSYPH 863 P P + L S ++ P P+ E QP P + + ++ Sbjct: 2472 PQ-PPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQP-PNFVRSPGTGAFVG 2529 Query: 864 HATQLHAHQPQPATTPTGSQPQSQHAAPSP--VQHQAGQAPHLGSGQPQQNLYHPGALTG 921 + + PQ P+ P Q P P + G P LG +PQ Y Sbjct: 2530 TPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLG--KPQSTNYTVATGNF 2587 Query: 922 TPPSLPPGPSAQS-----------PQSSFPQPAAVYAIHHQQLPHGFTNMAHVT 964 P P GPS+ S P S P PA ++ + L HG + + +T Sbjct: 2588 HPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPY--LSHGASQRSGIT 2639 Score = 53.9 bits (128), Expect = 8e-07 Identities = 162/801 (20%), Positives = 262/801 (32%), Gaps = 142/801 (17%) Query: 308 QYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIP-----LPQRVREGPRG 362 +YR + + + ++++HSAV + L G+ +P PQ G G Sbjct: 3594 EYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAG 3653 Query: 363 GVRCSSSRGGRPGLSSLP-----------------------PRG---PHHLDNSSPGPGS 396 G+R + PG P P G P +L S GP S Sbjct: 3654 GLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDS 3713 Query: 397 ---EARGINGGPSRMS-----------PKAQRPLRGAKTLSSPSNR-PSGETSVPPPPAV 441 + R + RM + Q+ L G + + P +T+ P Sbjct: 3714 RLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKP 3773 Query: 442 GRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISL 501 + PP S + +S P+ P G P A + G++ P P + Sbjct: 3774 QGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVL------QQQHPGALGPQGPHRQV 3827 Query: 502 APTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPS---- 557 T + LS+ + L Q + ++ Q +Q++ Q ++ LQ S Sbjct: 3828 LMTQSRVLSSPQ----LAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSH 3883 Query: 558 -SSPENSLDPFPP-RILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPS 615 P+ S P + L+++ + ++++ + + + + + ++ + L Sbjct: 3884 SGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQ 3943 Query: 616 GGTE----------GPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKE 665 + +Q Q +GL+ P +Q ++ L P Sbjct: 3944 QQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGM-- 4001 Query: 666 FNPTKPLL--------------------SVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGL 705 P KPL +V+ + S+ + GP TH + + T +S Sbjct: 4002 --PAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMA 4059 Query: 706 YSPQYISYIPQIHMGPAVQAPQMYPYPVSNSV--------PGQQGK-----YRGAKGSLP 752 P + P + + Q P P +S+ PGQQ + + GS Sbjct: 4060 TEPGEVK--PSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHG 4117 Query: 753 PQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHY--PS 810 S AS+ P + A P V+ + N P QP + +PM + P Sbjct: 4118 QLGSGSSSEASSVPHLLAQ-----PSVSLGDQPGSMTQNLLG-PQQPMLERPMQNNTGPQ 4171 Query: 811 QPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHA 870 P P+LQS + G P + Q A+ P + L Q Q Sbjct: 4172 PPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQL 4231 Query: 871 HQPQPAT-TPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPG 929 Q Q TP +P +Q SP+Q G P LG PG TG L G Sbjct: 4232 QQSQAVRQTPPYQEPGTQ---TSPLQGLLGCQPQLGG--------FPGPQTGPLQELGAG 4280 Query: 930 PSAQSPQ---------SSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAA-PPPH 979 P Q P S+ P V+ P + + Q A PP H Sbjct: 4281 PRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTH 4340 Query: 980 PGAPHPPQVMLLHPPQSHGGP 1000 PG P PQ L PP P Sbjct: 4341 PGTP-KPQGPTLEPPPGRVSP 4360 Score = 53.1 bits (126), Expect = 1e-06 Identities = 112/505 (22%), Positives = 157/505 (31%), Gaps = 108/505 (21%) Query: 341 SLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPH--------------- 385 SL E +PLP+ + PR S R P LS P PH Sbjct: 717 SLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEE-PHLSPQAEEPHLSPQPE 775 Query: 386 -----------HLDNSSPGP--GSEARGINGGPS----RMSPKAQRPLRGAKTLSSPSNR 428 HL + GP + ++ P +SP + P + S + Sbjct: 776 EPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSP 835 Query: 429 PSGETSVPPPPAVGRM-----YPPRSPKSAAPAPISASCPEPPIGSAVP----TSSASIP 479 S E + P P + PP SP+ P CP P P S + + Sbjct: 836 QSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLL 895 Query: 480 VTSSVSDPGVGSISPASPKISLAPTDVKELSTK-EPGRTLEPQELARIAGKVPGLQNEQK 538 ++S+PG +SP ++ L+P+ LS + P L P I P Sbjct: 896 GEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPP------ 949 Query: 539 RFQLEELRKFGAQFKLQPSSSPENSL--------------------DPFPPRILKEEPKG 578 L L + F + S PE+ L +P PP IL P Sbjct: 950 --ALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGS 1007 Query: 579 KEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSP--P 636 +L EP+ S + ++ PP S PP P SP P Sbjct: 1008 PVGPASPIL-MEPLPPQCSPLLQHSLVPQNSPPSQCS---------PPALPLSVPSPLSP 1057 Query: 637 VGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNP--TKPLLSVNKSTSTPT-SPGPRTHSTP 693 +G + G DE + E + P P T PL S S P SP P Sbjct: 1058 IGKVVGV-SDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFS 1116 Query: 694 SIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQ-QGKYRGAKGSLP 752 + TA G + AP P P PG + +G+ L Sbjct: 1117 GLGEDTAPLDG------------------IDAPGSQPEP--GQTPGSLASELKGSPVLLD 1156 Query: 753 PQRSDQHQPASAPPMMQAAAAAGPP 777 P+ P P + A G P Sbjct: 1157 PEELAPVTPMEVYPECKQTAGQGSP 1181 Score = 45.8 bits (107), Expect = 2e-04 Identities = 162/717 (22%), Positives = 240/717 (33%), Gaps = 148/717 (20%) Query: 377 SSLPPRGPHHL---DNSSPGP---GSEARGINGGPSRMSPKAQRPLRGAKTLS-SPSNRP 429 +S P GP +L D+ S G G E + + + ++P+A + + L P P Sbjct: 2294 ASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPP 2353 Query: 430 SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGV 489 + P PP+ ++ P S P P+PP P S ++P S SDP Sbjct: 2354 PAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPP----PPESCCALPPRSLPSDPF- 2408 Query: 490 GSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFG 549 S PASP+ + S++ P L P+ L+ A + RFQ + Sbjct: 2409 -SRVPASPQ--------SQSSSQSP---LTPRPLSAEAFCPSPVT---PRFQSPDPYS-- 2451 Query: 550 AQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD---GLLTSEPMGS---PVSSKTESV 603 +P S P+ S DPF P L + P+ + EV G L +G+ P + Sbjct: 2452 -----RPPSRPQ-SRDPFAP--LHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPA 2503 Query: 604 SDKEDKPPLAP---------SGGTEGPEQP--------------PPPCPSQTGSPPVGLI 640 + K P +G G P PP P PP G+ Sbjct: 2504 GELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGI- 2562 Query: 641 KGEDKDEGPVAEQVKKSTLNPNAKEFNPT-KPLLSVNKSTST--------PTSPGPRTHS 691 GP + + + F+P+ PL + ST P S P Sbjct: 2563 -NSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAP 2621 Query: 692 TPSIPVLTAG---QSGLYSPQYISYIPQIHMG--------PAVQAPQMYPYPVS------ 734 S+P L+ G +SG+ SP P MG P Q P M + Sbjct: 2622 DGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQR 2681 Query: 735 ----------------NSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPL 778 N++ ++ A G++ P S +P+S P + + P Sbjct: 2682 QRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSS--PAFEQLSRGQTPF 2739 Query: 779 VAATPYSSYIPYNPQQFPGQ---PAMM--QPMAHYPSQPVFAPMLQSNPRMLTSGSHPQA 833 SS + P + G P P P + N R L GS QA Sbjct: 2740 AGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGS--QA 2797 Query: 834 IVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQ-SQHAAPS 892 + YP + P Q Q AT + A P+ P+ + A S Sbjct: 2798 FYQRAP--YPGS-LPLQQQQQQLWQQQQATAATSMRF--AMSARFPSTPGPELGRQALGS 2852 Query: 893 PVQHQAGQAPHLGSGQPQQNLYHPGALT--------GTPPSLPPGPSAQSPQSSFPQPAA 944 P+ + + P G G+P P G P P P PQ P+ Sbjct: 2853 PLAGISTRLP--GPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQR--PRFYP 2908 Query: 945 VYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQV-MLLHPPQSHGGP 1000 V H+ P G +A ++ PP P AP P++ LHP GP Sbjct: 2909 VSEDPHRLAPEGLRGLA----------VSGLPPQKPSAPPAPELNNSLHPTPHTKGP 2955 Score = 43.9 bits (102), Expect = 8e-04 Identities = 88/358 (24%), Positives = 135/358 (37%), Gaps = 61/358 (17%) Query: 361 RGGVRCSSSRGGRPGLSSLP---------PRGPHHLDNSSPGPGSEARGINGGPSRMSP- 410 +G + C GG PG + P P+GP L PG+ + G GP +P Sbjct: 4254 QGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAP---PGALSTGPVLGPVHPTPP 4310 Query: 411 --KAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIG 468 Q P R ++ L SPS++ E +PP P +PK P EPP G Sbjct: 4311 PSSPQEPKRPSQ-LPSPSSQLPTEAQLPPT-------HPGTPKPQGPT------LEPPPG 4356 Query: 469 SAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAG 528 P A+ + ++ G+G P P +LA T E S+ PG L ++ G Sbjct: 4357 RVSP---AAAQLADTLFSKGLG---PWDPPDNLAETQKPEQSSLVPG------HLDQVNG 4404 Query: 529 KV--PGLQNEQKRFQLEELRKFGAQ-FKLQPSSSP------ENSLDPFPPR------ILK 573 +V Q K+ EE GAQ K + + P N L PR +L+ Sbjct: 4405 QVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQ 4464 Query: 574 EEPKGKEKEVDGLLTSEPMGSPVSSKTES-VSDKEDKPPLAPSGGTEG----PEQPPPPC 628 + + K ++ SE + + ++ +S ++ E K PS + P P P Sbjct: 4465 KLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPLTPKPKR 4524 Query: 629 PSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPG 686 + V K K++G A + L T+P ++ N S P G Sbjct: 4525 VQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSG 4582 Score = 39.3 bits (90), Expect = 0.020 Identities = 90/379 (23%), Positives = 122/379 (32%), Gaps = 62/379 (16%) Query: 721 PAVQAPQMY---PYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPP 777 P AP ++ P + G + GS+P S PP + A + P Sbjct: 2117 PPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDP 2176 Query: 778 LVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQA---- 833 A Y P P+ FP P P YPS P AP + P ML + S P A Sbjct: 2177 FGLAPAY----PLEPR-FPTAPPTYPP---YPS-PTGAP---AQPPMLGASSRPGAGQPG 2224 Query: 834 IVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLH-------AHQPQPATTPTGSQPQS 886 ++ P P + TP S + A A +P + P G ++ Sbjct: 2225 EFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKA 2284 Query: 887 QHAAPSPVQHQAGQ--APHLGSGQPQQNLYHPGALTGTPPS-----LPPGPSAQSPQS-- 937 + + P+LG + H G L P L P S PQS Sbjct: 2285 LEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPG 2344 Query: 938 -----SFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLH 992 P PA A P F ++ T + Q +T P P P P+ Sbjct: 2345 LGLRPQEPPPAQALAPSPPSHPDIFRPGSY-TDPYAQPPLTPRPQPPP-----PESCCAL 2398 Query: 993 PPQSHGGPPQGAVPQSGVPALSASTP-----------SPYPYIGHPQGEQP-GQAPGFPG 1040 PP+S P VP S S+ +P P P Q P + P P Sbjct: 2399 PPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQ 2458 Query: 1041 GADD----RIPPLPPPGEL 1055 D PP P P E+ Sbjct: 2459 SRDPFAPLHKPPRPQPPEV 2477 Score = 39.3 bits (90), Expect = 0.020 Identities = 33/112 (29%), Positives = 43/112 (38%), Gaps = 22/112 (19%) Query: 1 MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 +L + LQQ +Q PP Q+ PG + P GL G PGP G Sbjct: 4225 LLMQRQLQQSQAVRQTPPYQE------PGTQTSPLQGLLGCQPQLGGFPGPQT------G 4272 Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112 P+ G+G P+P P + PGA + G G PP SP Sbjct: 4273 PLQELGAG----------PRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSP 4314 Score = 34.3 bits (77), Expect = 0.64 Identities = 32/120 (26%), Positives = 43/120 (35%), Gaps = 10/120 (8%) Query: 2 LKPQPLQQPSQ--PQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCL 59 L+ PL P + P PPP + SPP P P + P PP ASP Sbjct: 489 LEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALET--PLSPPPEASPLS 546 Query: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS----PVFE 115 P S L E + PP + P + + +S PP++ P FE Sbjct: 547 PPFEE--SPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFE 604 Score = 33.9 bits (76), Expect = 0.84 Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 21/97 (21%) Query: 2 LKPQ-PLQQPSQPQQPPPTQQAVARRPP--GGTSPPNGGLPGPLATSAAPPG----PPAA 54 L+P+ P P+ P P PT +PP G +S P G PG T+ PPG P+ Sbjct: 2185 LEPRFPTAPPTYPPYPSPT--GAPAQPPMLGASSRPGAGQPGEFHTT--PPGTPRHQPST 2240 Query: 55 ASPCLGP----------VAAAGSGLRRGAEGILAPQP 81 P L P + G G + +E +L+P P Sbjct: 2241 PDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPP 2277 Score = 33.9 bits (76), Expect = 0.84 Identities = 85/391 (21%), Positives = 128/391 (32%), Gaps = 66/391 (16%) Query: 561 ENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEG 620 +N++DP + E +G G P+ + ++ + E KP L+ Sbjct: 4026 QNTVDP---AVSSEATEGPSTHQGG-----PLAIGTTPESMATEPGEVKPSLSGDSQLLL 4077 Query: 621 PEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQV---KKSTLNPNAKEFNPTKPLLSVNK 677 + P P PS P + G+ + + + L + + P L Sbjct: 4078 VQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQP 4137 Query: 678 STSTPTSPGPRTHST--PSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSN 735 S S PG T + P P+L PQ GP +Q+ Q P Sbjct: 4138 SVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQ------PPKPGPVLQSGQGLPGVGIM 4191 Query: 736 SVPGQ-QGKYRGAKGSLP------PQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYI 788 GQ + + +G P PQ+ Q Q +Q + A V TP Sbjct: 4192 PTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQA-----VRQTP----- 4241 Query: 789 PYNPQQFPG-QPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQ 847 P Q PG Q + +Q + Q P Q+ P Q + + PQ P Sbjct: 4242 ---PYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPL--------QELGAGPRPQGPP-RL 4289 Query: 848 PTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSG 907 P P +T P H T P ++P + SQ +PS Q P Sbjct: 4290 PAPPGALSTGPVLGPVHPTP-------PPSSPQEPKRPSQLPSPSSQLPTEAQLPPT--- 4339 Query: 908 QPQQNLYHPGALTGTPPSLPPGPSAQSPQSS 938 HPG P+L P P SP ++ Sbjct: 4340 -------HPGTPKPQGPTLEPPPGRVSPAAA 4363 Score = 33.5 bits (75), Expect = 1.1 Identities = 34/125 (27%), Positives = 50/125 (40%), Gaps = 16/125 (12%) Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61 L P+P + P +P Q P ++ PPG P L G A S PG P SP Sbjct: 860 LSPRPEKPPEEPGQCPAPEELPLFPPPG--EPSLSPLLGEPALS--EPGEP-PLSPLPEE 914 Query: 62 VAAAGSGLRRGAEGILAPQPPPPQ-----QHQERPGAAAIG------SARGQSTGKGPPQ 110 + + SG + ++ P P PP P + +G A+G S + P Sbjct: 915 LPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLA 974 Query: 111 SPVFE 115 +P+ E Sbjct: 975 APILE 979 Score = 33.5 bits (75), Expect = 1.1 Identities = 23/75 (30%), Positives = 28/75 (37%), Gaps = 4/75 (5%) Query: 974 AAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPG 1033 +APPP P PP L P S P +P P PSP P P+ +P Sbjct: 4907 SAPPPEE--PSPPPSPLAPSPASPPTEPLVELPTE--PLAEPPVPSPLPLASSPESARPK 4962 Query: 1034 QAPGFPGGADDRIPP 1048 P +D PP Sbjct: 4963 PRARPPEEGEDSRPP 4977 Score = 32.3 bits (72), Expect = 2.4 Identities = 42/143 (29%), Positives = 54/143 (37%), Gaps = 9/143 (6%) Query: 923 PPSLPPGPSAQSPQSSFPQ-PAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPP-PHP 980 P PGP SP F + P V A Q P G A+ + T PP P P Sbjct: 2146 PAGSVPGPD--SPGELFLKLPPQVPAQVPSQDPFGLAP-AYPLEPRFPTAPPTYPPYPSP 2202 Query: 981 -GAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPY--PYIGHPQGEQPGQAPG 1037 GAP P ++ G P + G P STP P+ P ++PG Sbjct: 2203 TGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPG 2262 Query: 1038 FPGG-ADDRIPPLPPPGELKIVL 1059 GG A + + PP GE + L Sbjct: 2263 VGGGKASEPLLSPPPFGESRKAL 2285 Score = 32.0 bits (71), Expect = 3.2 Identities = 38/130 (29%), Positives = 46/130 (35%), Gaps = 28/130 (21%) Query: 1 MLKPQPLQQPSQPQQPPP-------TQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPA 53 +++PQP QPS Q PP QQ GG S G G ++S A P Sbjct: 4077 LVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGS---HGQLGSGSSSEASSVPHL 4133 Query: 54 AASPCLGPVAAAGS-----------GLRRGAEGILAPQPPPP----QQHQERPGAA---A 95 A P + GS L R + PQPP P Q Q PG Sbjct: 4134 LAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPT 4193 Query: 96 IGSARGQSTG 105 +G R Q G Sbjct: 4194 VGQLRAQLQG 4203 Score = 31.6 bits (70), Expect = 4.2 Identities = 22/74 (29%), Positives = 27/74 (36%), Gaps = 1/74 (1%) Query: 16 PPPTQQAVARRPPGGTSPPNGGLPG-PLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAE 74 PP V + P G +P P P A PP P +P P+ A S G Sbjct: 2164 PPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQP 2223 Query: 75 GILAPQPPPPQQHQ 88 G PP +HQ Sbjct: 2224 GEFHTTPPGTPRHQ 2237 Score = 31.2 bits (69), Expect = 5.4 Identities = 34/124 (27%), Positives = 44/124 (35%), Gaps = 23/124 (18%) Query: 3 KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPV 62 K Q QQ Q QQ Q A+ ++ G PG A P P P Sbjct: 3733 KLQQQQQQQQQQQHLLGQVAIQQQQQQG--------PGVQTNQALGPKPQGLMPPS---- 3780 Query: 63 AAAGSGLRRGAEGILAPQ--PPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120 +G+L Q P PPQ Q G A + + Q G PQ P + + Sbjct: 3781 ---------SHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQ 3831 Query: 121 SRML 124 SR+L Sbjct: 3832 SRVL 3835 Score = 31.2 bits (69), Expect = 5.4 Identities = 31/112 (27%), Positives = 42/112 (37%), Gaps = 22/112 (19%) Query: 834 IVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSP 893 I+S + P+ E PT SY ++ + L Q A P P APSP Sbjct: 4875 ILSLLKQESPAPEPPT--------QHSYTYNVSNLDVRQLS-APPPEEPSPPPSPLAPSP 4925 Query: 894 VQHQAGQAPHLGSGQPQQNLYH-PGALTGTPPSLPPGPSAQSPQSSFPQPAA 944 + P + L P PP P P A SP+S+ P+P A Sbjct: 4926 ------------ASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRA 4965 Score = 30.4 bits (67), Expect = 9.2 Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 11/93 (11%) Query: 5 QPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAA 64 +PL++ P PPP + ++ PP +SP + PL+ P PA +P L P Sbjct: 487 RPLEE--SPLSPPPEESPLS--PPPESSPFSPLEESPLSPPEESPPSPALETP-LSPPPE 541 Query: 65 AGSGLRRGAEGILAPQP------PPPQQHQERP 91 A E L+P P PPP+ + P Sbjct: 542 ASPLSPPFEESPLSPPPEELPTSPPPEASRLSP 574 Score = 30.4 bits (67), Expect = 9.2 Identities = 83/369 (22%), Positives = 113/369 (30%), Gaps = 80/369 (21%) Query: 740 QQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQP 799 QQ + + G + Q+ Q P +Q A GP P SS+ QQ QP Sbjct: 3740 QQQQQQHLLGQVAIQQQQQQGPG-----VQTNQALGPKPQGLMPPSSHQGLLVQQLSPQP 3794 Query: 800 AMMQPMAHYPSQPVFAPMLQSNPRML-TSGSHPQAIVSSS----TPQYPSAEQPTPQALY 854 P+Q A + Q +P L G H Q +++ S +PQ Q Sbjct: 3795 PQGPQGMLGPAQ--VAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRL 3852 Query: 855 ATVHQ----------------SYPHHATQLHAHQPQPATTPTGS--------QPQSQHAA 890 T Q S+ + H+ QP+ + P GS Q Q Q Sbjct: 3853 VTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQL 3912 Query: 891 PSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHH 950 Q Q Q L Q QQ L Q Q Q + Sbjct: 3913 QQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQ--QQQQQLQQQQQQQQQQFQQQQ 3970 Query: 951 QQLPHGFTNMAHV---------TQAHVQTGITAAPPPH---PGAPHPPQVM--------- 989 QQ G N + Q + G+ A P H PGA P ++ Sbjct: 3971 QQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVD 4030 Query: 990 ------LLHPPQSHGGPPQ--GAVPQSGV-------PALSAST------PSPYPYIGHPQ 1028 P +H G P G P+S P+LS + P P P Q Sbjct: 4031 PAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQ 4090 Query: 1029 GEQPGQAPG 1037 + P + PG Sbjct: 4091 LQPPLRLPG 4099 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 97.1 bits (240), Expect = 8e-20 Identities = 189/782 (24%), Positives = 264/782 (33%), Gaps = 148/782 (18%) Query: 357 REGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGING-GPSRMSPKAQRP 415 R+ + G + PGL L PR P P + R + G P A+R Sbjct: 5 RDKAKAGAAARTPAARAPGL--LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERA 62 Query: 416 LRGAKTLSSPSNRP-SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTS 474 G + P + P +G T PPA GR K+ +P P+S+ P G+ P Sbjct: 63 -GGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSS--PGRASGTTRP-- 117 Query: 475 SASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELAR-IAGKVPGL 533 G + +IS T + +T+ P R+ R +G PG Sbjct: 118 ---------------GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGT 162 Query: 534 QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593 + R G + L P S P PP E P+ T+EP Sbjct: 163 PSPA---MARRSRAAGTEVGLP---RPAPSARPRPPT---EGPRKSVSSASEHSTTEP-- 211 Query: 594 SPVSSKTESVSDKEDKPPLAPSGGTEGP-EQPPPPCPSQTGSPPVGLIKGEDKDEGPVAE 652 SP + + S +P + P P PS G+P + K +G + Sbjct: 212 SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG--LQ 269 Query: 653 QVKKSTLNPNAKEFNPTK-PLLSVNKSTSTPTSPG-----PRTHSTPSIPVLTAGQS--G 704 ++ + P K+ P PL S +T +P++P P + PS P Q+ Sbjct: 270 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTS 329 Query: 705 LYSPQYI---SYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQP 761 L SP S++P + P P P ++ LPP ++ P Sbjct: 330 LGSPTLQATHSFLPSPPLSPLATPPPQAPPALA----------------LPPLQAPPSPP 373 Query: 762 ASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSN 821 AS PP+ A + A + P++P P A P A P P P Q+ Sbjct: 374 AS-PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 432 Query: 822 PRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTG 881 P + +S P PSA P PQA P A L +P P P Sbjct: 433 PSLAAPPLQVPPSPPASPPMSPSA-TPPPQA-------PPPLAAPPLQLAKPPPQAPPAL 484 Query: 882 SQPQSQHAAPSPVQHQAGQAPH----------LGSGQPQQNLYHPGALTGTPPSLPPGPS 931 + P Q A PSP GQAP L + PQ L PPS P P+ Sbjct: 485 ATPPLQ-ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 543 Query: 932 AQSPQ--------SSFPQPAAVYAIHHQQLP---------------HGFTNMAHVTQAHV 968 Q+P+ +S P A+ P G ++ A T + Sbjct: 544 LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL 603 Query: 969 -------QTGITAAPPP-------HPGA----PHPPQVM-------LLHPPQSHGGPPQG 1003 + G A+PPP HP A P PP L PP + G G Sbjct: 604 RGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADG 663 Query: 1004 AV-------PQSGVPALSASTPSPYPYIGHPQGEQPGQ-APGFPGGADDRIPPLPPPGEL 1055 P+S PA A P P P G G+ A G GA R P GEL Sbjct: 664 LCTIYETEGPESATPAPGALDPGPSP------GTSGGKAAAGAGAGASSRSPKQARLGEL 717 Query: 1056 KI 1057 + Sbjct: 718 PL 719 Score = 78.6 bits (192), Expect = 3e-14 Identities = 131/527 (24%), Positives = 180/527 (34%), Gaps = 70/527 (13%) Query: 585 GLLTSEPMGSP--------VSSKTESVSDKEDKPPLAPSGGTEG----PEQPPPPCPSQT 632 GLLT P GSP + + + + PLA G G PE P P++T Sbjct: 23 GLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRT 82 Query: 633 GSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKP----LLSVNKSTSTPTSPGPR 688 PP +GE P A+ ++ + T+P + S + G Sbjct: 83 SRPPASG-RGE---RAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKA 138 Query: 689 THSTPSIPVLTAGQS--------GLYSPQYI--SYIPQIHMGPAVQAPQMYPYPVSNSVP 738 T + P L+AG G SP S +G AP P P + P Sbjct: 139 TEA-PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG-P 196 Query: 739 GQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQ----- 793 + + P + + +P++ + + A+ + +ATP SS P Sbjct: 197 RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS--SATPLSSPARSGPSARGTP 254 Query: 794 QFPGQPAMMQPMAHYPSQP--VFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQ---- 847 + P P+ +P +P V P + P + S P A S S P PSA Sbjct: 255 RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQT 314 Query: 848 -PTPQAL---YATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPH 903 P+P A AT P H+ P P +P + P A + QA +P Sbjct: 315 LPSPPATPPSQATTSLGSPT-LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP 373 Query: 904 -------LGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHG 956 L + PQ L P S PP P Q+P F PA+ P Sbjct: 374 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP---FSPPASPPVSPSATPPSQ 430 Query: 957 FTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVM--LLHPPQSHGGPPQGAVPQSGVPALS 1014 V A+PP P A PPQ L PP PP A P P L Sbjct: 431 APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQ 490 Query: 1015 ASTPSPYPYIGHPQGEQPGQAPGFPGGADDRIPPLPPPGELKIVLAA 1061 A P + PGQAP P + P PP + VLAA Sbjct: 491 ALPSPPASF--------PGQAPFSPSASLPMSPLATPPPQAPPVLAA 529 Score = 39.7 bits (91), Expect = 0.015 Identities = 33/123 (26%), Positives = 44/123 (35%), Gaps = 22/123 (17%) Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTS------------PPNGGLPGPLATSAAPPGPPA 53 PLQ P P PP P + PP+ + P + A+PP P+ Sbjct: 365 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 424 Query: 54 AASPCLGPVAAAGSGLRRGAEGILAPQPP--PPQQHQERPGAAAIG--SARGQSTGKGPP 109 A P P + A L+ + P PP PP P A +A K PP Sbjct: 425 ATPPSQAPPSLAAPPLQ------VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 478 Query: 110 QSP 112 Q+P Sbjct: 479 QAP 481 Score = 38.1 bits (87), Expect = 0.044 Identities = 35/110 (31%), Positives = 46/110 (41%), Gaps = 22/110 (20%) Query: 10 PSQPQQPPPTQQAVARRPPGGTSPPNGGLP--GPLATS-AAPPGPPAAASPCLGPVAAAG 66 P+ P QP P + A RPP T P P GPL++S A P P A SP P Sbjct: 257 PAHPSQPKP-KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPP----- 310 Query: 67 SGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK---GPPQSPV 113 + + +P PP Q ++GS Q+T PP SP+ Sbjct: 311 -----SLQTLPSPPATPPSQ-----ATTSLGSPTLQATHSFLPSPPLSPL 350 Score = 37.0 bits (84), Expect = 0.099 Identities = 34/122 (27%), Positives = 48/122 (39%), Gaps = 15/122 (12%) Query: 3 KPQPLQQPSQPQQPPPTQQAVAR---------RPPGGTSPPNGGLPGPLATSAAPPG-PP 52 KP+ LQ PQ PP + A P ++PP+ P L T +PP PP Sbjct: 264 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPP 323 Query: 53 AAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARG-QSTGKGPPQS 111 + A+ LG + + + PPPQ P A A+ + S PP S Sbjct: 324 SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ----APPALALPPLQAPPSPPASPPLS 379 Query: 112 PV 113 P+ Sbjct: 380 PL 381 Score = 37.0 bits (84), Expect = 0.099 Identities = 39/122 (31%), Positives = 48/122 (39%), Gaps = 30/122 (24%) Query: 13 PQQPP--PTQQAVARRPPGGTSPPNGGLPGP---LATSAAPPGPP--AAASPCLGPVAAA 65 P PP PT QA RRPP T P+ + GP LA + PP PP + +S GP A Sbjct: 535 PPSPPASPTLQA-PRRPP--TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 591 Query: 66 GS-----------GLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVF 114 S G G EG A PPP A + + + +GP F Sbjct: 592 HSSSATSTPEELRGYDSGPEGGAAASPPPD---------AELAACHPAAWSRGPAPPLAF 642 Query: 115 EG 116 G Sbjct: 643 RG 644 Score = 33.9 bits (76), Expect = 0.84 Identities = 36/125 (28%), Positives = 43/125 (34%), Gaps = 27/125 (21%) Query: 4 PQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLAT---------SAAPPGPPAA 54 P PL P PP Q PP +PP LP P A+ SA+ P P A Sbjct: 463 PPPLAAPPLQLAKPPPQA-----PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 517 Query: 55 ASPCLGPVAAAGSGLRRGAEGILAPQPP--PPQQHQER-----PGAAAIGSARGQSTGKG 107 P P A L+ + P PP P Q R P + G + G Sbjct: 518 TPPPQAPPVLAAPLLQ------VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 571 Query: 108 PPQSP 112 PP P Sbjct: 572 PPPPP 576 Score = 33.1 bits (74), Expect = 1.4 Identities = 39/143 (27%), Positives = 55/143 (38%), Gaps = 34/143 (23%) Query: 1 MLKPQPLQQPSQPQQPPPTQQ----------AVARRP--------PGGTSPPNGGLPGPL 42 +L P+P P P+ PPP AV R+P G T P + GP Sbjct: 24 LLTPRP---PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT 80 Query: 43 ATSAAPPG-----PPAAASPCLGPVAAAG--SGLRR----GAEG--ILAPQPPPPQQHQE 89 TS P P A + GPV++ G SG R G +G I A + + E Sbjct: 81 RTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE 140 Query: 90 RPGAAAIGSARGQSTGKGPPQSP 112 P +A+ + + T P +P Sbjct: 141 APKRSALSAGARRDTSGPTPGTP 163 Score = 32.0 bits (71), Expect = 3.2 Identities = 30/100 (30%), Positives = 36/100 (36%), Gaps = 12/100 (12%) Query: 10 PSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGL 69 P P PP Q PP PP L P + A+PP P A P A A L Sbjct: 346 PLSPLATPPPQ-----APPALALPP---LQAPPSPPASPPLSPLATPSPQAPNALAVHLL 397 Query: 70 RRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109 + +P P PP Q P A+ S + PP Sbjct: 398 ----QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 433 Score = 31.6 bits (70), Expect = 4.2 Identities = 33/119 (27%), Positives = 43/119 (36%), Gaps = 21/119 (17%) Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPG-P---PAAASPCLGP 61 P+Q P P PP + P +PP+ P PL +PP P P+A P P Sbjct: 408 PVQAPFSPPASPPVSPSAT---PPSQAPPSLAAP-PLQVPPSPPASPPMSPSATPPPQAP 463 Query: 62 VAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGP-------PQSPV 113 A L+ LA PP P A+ S G+ P P SP+ Sbjct: 464 PPLAAPPLQ------LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 516 Score = 31.6 bits (70), Expect = 4.2 Identities = 29/91 (31%), Positives = 34/91 (37%), Gaps = 13/91 (14%) Query: 16 PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEG 75 PPP + A P + P PLA AP G P P GP +A G EG Sbjct: 618 PPPDAELAACHPAAWSRGP----APPLAFRGAP-GAPLPWPPATGPGSADGLCTIYETEG 672 Query: 76 ILAPQPPPPQQHQERPGAAAIGSARGQSTGK 106 P+ PGA G + G S GK Sbjct: 673 --------PESATPAPGALDPGPSPGTSGGK 695 Score = 30.4 bits (67), Expect = 9.2 Identities = 31/126 (24%), Positives = 45/126 (35%), Gaps = 21/126 (16%) Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGP--------PAAASP 57 P P++ +PP + + P TSP PG A+ PGP A + Sbjct: 75 PRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPG-RASGTTRPGPLGQKGLRISAEETV 133 Query: 58 CLGPV------AAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIG------SARGQSTG 105 G +A +G RR G P P + R +G SAR + Sbjct: 134 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 193 Query: 106 KGPPQS 111 +GP +S Sbjct: 194 EGPRKS 199 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 91.7 bits (226), Expect = 3e-18 Identities = 194/793 (24%), Positives = 262/793 (33%), Gaps = 202/793 (25%) Query: 357 REGP-RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRP 415 R GP R S + RP S R P N+SPGP S G G +R P Q+ Sbjct: 76 RAGPTRSAGTSSRNPASRPPASGRGERAPP-AKNTSPGPVSSP-GRASGTTRPGPLGQKG 133 Query: 416 LR---------GAKT-------LSSPSNRP-SGETSVPPPPAVGRMYPPRSPKSAAPAPI 458 LR G T LS+ + R SG T P PA+ R + P P Sbjct: 134 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 193 Query: 459 SASCPEPPI-GSAVPTSSASIPVTSSVS-------DPGVGSISPASPKISLAPTDVKELS 510 ++ P PP G SSAS T+ S G G PAS +S + T + + Sbjct: 194 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253 Query: 511 TKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPR 570 P AR + P ++ K L+ LR PP+ Sbjct: 254 RSGPS--------ARGTPRAPAHPSQPKPKGLQALR---------------------PPQ 284 Query: 571 ILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPS 630 + P+ G L+S P+ +P +PS + Q PP P+ Sbjct: 285 VTP--PRKDAAPALGPLSSSPLATP-----------------SPSAALQS--QAPPTLPA 323 Query: 631 QTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTH 690 S + +A + + +P+A T P S P +P + Sbjct: 324 TPHSSSLTC---------QLATPLPLAPPSPSAPPSLQTLP--------SPPATPPSQAT 366 Query: 691 STPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGS 750 ++ P L A S L SP + P P P ++ Sbjct: 367 TSLGSPTLQATHSFLPSPP---------LSPLATPPPQAPPALA---------------- 401 Query: 751 LPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPS 810 LPP ++ PAS PP+ A + A + P++P P A P A P Sbjct: 402 LPPLQAPPSPPAS-PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 460 Query: 811 QPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHA 870 P P Q+ P + +S P PSA P PQA P A L Sbjct: 461 SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA-TPPPQA-------PPPLAAPPLQL 512 Query: 871 HQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPH----------LGSGQPQQNLYHPGALT 920 +P P P + P Q A PSP GQAP L + PQ L Sbjct: 513 AKPPPQAPPALATPPLQ-ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL 571 Query: 921 GTPPSLPPGPSAQSPQ--------SSFPQPAAVYAIHHQQLP---------------HGF 957 PPS P P+ Q+P+ +S P A+ P G Sbjct: 572 QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGH 631 Query: 958 TNMAHVTQAHV-------QTGITAAPPP-------HPGA----PHPPQVM-------LLH 992 ++ A T + + G A+PPP HP A P PP L Sbjct: 632 SSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPW 691 Query: 993 PPQSHGGPPQGAV-------PQSGVPALSASTPSPYPYIGHPQGEQPGQ-APGFPGGADD 1044 PP + G G P+S PA A P P P G G+ A G GA Sbjct: 692 PPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP------GTSGGKAAAGAGAGASS 745 Query: 1045 RIPPLPPPGELKI 1057 R P GEL + Sbjct: 746 RSPKQARLGELPL 758 Score = 82.8 bits (203), Expect = 2e-15 Identities = 156/653 (23%), Positives = 214/653 (32%), Gaps = 127/653 (19%) Query: 440 AVGRMYPPRSPKSAAPAPISASCPEPPIGSA---VPTSSASI---PVTSSVSDPGVGSIS 493 A R R+P P P + P PP+ A V ++ ++ P+ G +I Sbjct: 12 AAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71 Query: 494 PASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFK 553 ++P+ PT S++ P P R + P +N Sbjct: 72 ESAPRAG--PTRSAGTSSRNPAS--RPPASGR-GERAPPAKNTSPG-------------- 112 Query: 554 LQPSSSPENSLDPFPPRILKEEP---KGKEKEVDGLLTSEPMGSPVSS----KTESVSDK 606 P SSP + P L ++ +E G T P S +S+ T + Sbjct: 113 --PVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG 170 Query: 607 EDKPPLAPSGGTEGPEQP-PPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKE 665 P +A G E P P PS PP EGP +KS +A E Sbjct: 171 TPSPAMARRSRAAGTEVGLPRPAPSARPRPPT---------EGP-----RKSV--SSASE 214 Query: 666 FNPTKPLLSVNKSTSTPTS---PGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722 + T+P + + S P R+ S+ + P+ + +SG P P Sbjct: 215 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG----------PSARGTPR 264 Query: 723 VQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGP----PL 778 A P P +G + PPQ + PP AA A GP PL Sbjct: 265 APAHPSQPKP------------KGLQALRPPQVT--------PPRKDAAPALGPLSSSPL 304 Query: 779 VAATPYSSYIPYNPQQFPGQP-------AMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHP 831 +P ++ P P P + P+ P P P LQ+ P + Sbjct: 305 ATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPS- 363 Query: 832 QAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAP 891 QA S +P + P + + P L Q +P S P S A P Sbjct: 364 QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATP 423 Query: 892 SPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPP-GPSAQSPQSSFPQPAAVYAIHH 950 SP Q A HL P +PP+ PP PSA P + P AA Sbjct: 424 SP-QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA------ 476 Query: 951 QQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVM--LLHPPQSHGGPPQGAVPQS 1008 V A+PP P A PPQ L PP PP A P Sbjct: 477 -------------PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL 523 Query: 1009 GVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRIPPLPPPGELKIVLAA 1061 P L A P + PGQAP P + P PP + VLAA Sbjct: 524 ATPPLQALPSPPASF--------PGQAPFSPSASLPMSPLATPPPQAPPVLAA 568 Score = 39.7 bits (91), Expect = 0.015 Identities = 33/123 (26%), Positives = 44/123 (35%), Gaps = 22/123 (17%) Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTS------------PPNGGLPGPLATSAAPPGPPA 53 PLQ P P PP P + PP+ + P + A+PP P+ Sbjct: 404 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 463 Query: 54 AASPCLGPVAAAGSGLRRGAEGILAPQPP--PPQQHQERPGAAAIG--SARGQSTGKGPP 109 A P P + A L+ + P PP PP P A +A K PP Sbjct: 464 ATPPSQAPPSLAAPPLQ------VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 517 Query: 110 QSP 112 Q+P Sbjct: 518 QAP 520 Score = 37.0 bits (84), Expect = 0.099 Identities = 39/122 (31%), Positives = 48/122 (39%), Gaps = 30/122 (24%) Query: 13 PQQPP--PTQQAVARRPPGGTSPPNGGLPGP---LATSAAPPGPP--AAASPCLGPVAAA 65 P PP PT QA RRPP T P+ + GP LA + PP PP + +S GP A Sbjct: 574 PPSPPASPTLQA-PRRPP--TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 630 Query: 66 GS-----------GLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVF 114 S G G EG A PPP A + + + +GP F Sbjct: 631 HSSSATSTPEELRGYDSGPEGGAAASPPPD---------AELAACHPAAWSRGPAPPLAF 681 Query: 115 EG 116 G Sbjct: 682 RG 683 Score = 36.2 bits (82), Expect = 0.17 Identities = 35/124 (28%), Positives = 47/124 (37%), Gaps = 20/124 (16%) Query: 3 KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAA-------- 54 KP+ LQ PQ PP + A P +SP P S APP PA Sbjct: 273 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTC 332 Query: 55 --ASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK---GPP 109 A+P P+A + + +P PP Q ++GS Q+T PP Sbjct: 333 QLATPL--PLAPPSPSAPPSLQTLPSPPATPPSQ-----ATTSLGSPTLQATHSFLPSPP 385 Query: 110 QSPV 113 SP+ Sbjct: 386 LSPL 389 Score = 33.9 bits (76), Expect = 0.84 Identities = 36/125 (28%), Positives = 43/125 (34%), Gaps = 27/125 (21%) Query: 4 PQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLAT---------SAAPPGPPAA 54 P PL P PP Q PP +PP LP P A+ SA+ P P A Sbjct: 502 PPPLAAPPLQLAKPPPQA-----PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 556 Query: 55 ASPCLGPVAAAGSGLRRGAEGILAPQPP--PPQQHQER-----PGAAAIGSARGQSTGKG 107 P P A L+ + P PP P Q R P + G + G Sbjct: 557 TPPPQAPPVLAAPLLQ------VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 610 Query: 108 PPQSP 112 PP P Sbjct: 611 PPPPP 615 Score = 32.0 bits (71), Expect = 3.2 Identities = 30/100 (30%), Positives = 36/100 (36%), Gaps = 12/100 (12%) Query: 10 PSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGL 69 P P PP Q PP PP L P + A+PP P A P A A L Sbjct: 385 PLSPLATPPPQ-----APPALALPP---LQAPPSPPASPPLSPLATPSPQAPNALAVHLL 436 Query: 70 RRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109 + +P P PP Q P A+ S + PP Sbjct: 437 ----QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 472 Score = 31.6 bits (70), Expect = 4.2 Identities = 33/119 (27%), Positives = 43/119 (36%), Gaps = 21/119 (17%) Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPG-P---PAAASPCLGP 61 P+Q P P PP + P +PP+ P PL +PP P P+A P P Sbjct: 447 PVQAPFSPPASPPVSPSAT---PPSQAPPSLAAP-PLQVPPSPPASPPMSPSATPPPQAP 502 Query: 62 VAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGP-------PQSPV 113 A L+ LA PP P A+ S G+ P P SP+ Sbjct: 503 PPLAAPPLQ------LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 555 Score = 31.6 bits (70), Expect = 4.2 Identities = 29/91 (31%), Positives = 34/91 (37%), Gaps = 13/91 (14%) Query: 16 PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEG 75 PPP + A P + P PLA AP G P P GP +A G EG Sbjct: 657 PPPDAELAACHPAAWSRGP----APPLAFRGAP-GAPLPWPPATGPGSADGLCTIYETEG 711 Query: 76 ILAPQPPPPQQHQERPGAAAIGSARGQSTGK 106 P+ PGA G + G S GK Sbjct: 712 --------PESATPAPGALDPGPSPGTSGGK 734 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 86.7 bits (213), Expect = 1e-16 Identities = 146/545 (26%), Positives = 196/545 (35%), Gaps = 93/545 (17%) Query: 561 ENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTES-VSDKEDKPPLAPSGGTE 619 E +DP PP + K ++E DGL M + S + S + K P +P G T Sbjct: 546 EKPVDP-PPFMFKPV----KEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTS 600 Query: 620 GPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKST 679 + S SP D AE VKKS + +P K + Sbjct: 601 PINEDIRS--SGRNSPSAASTSSNDSK----AETVKKSAKKVKEEASSPLKSNKRQREKV 654 Query: 680 STPTSPGPRTHST---------PSIPVLTAGQS---------GLYSPQYISYIPQIHMGP 721 ++ T RT S P+ P G+S G P+ I + P Sbjct: 655 ASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNR-STSP 713 Query: 722 AVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAA 781 ++ +PQ +S QQ + +L P+SAPP GP Sbjct: 714 SIPSPQDNESDSDSSA--QQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP----- 766 Query: 782 TPYSSYIPYNPQQFP-GQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840 TP ++ +P PQ P A QP A P+ PV +Q P + HPQ S P Sbjct: 767 TPSATAVP--PQGSPTASQAPNQPQA--PTAPVPHTHIQQAPAL-----HPQRPPSPHPP 817 Query: 841 QYPSAEQPTPQALYATVHQSYPHHATQ-LHAHQPQPATTPTGSQPQSQHAAPS-----PV 894 +PS P + S P HA LH P P + P QH P P Sbjct: 818 PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGP-PGPHSLQAGPLLQHPGPPQPFGLPP 876 Query: 895 QHQAGQAPHLGSGQ----PQQNLYHPGALTGT----PPS---LPPGPSAQ--------SP 935 Q GQAP LG+ P +L P + + PP LPP P A +P Sbjct: 877 QASQGQAP-LGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP 935 Query: 936 QSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQ 995 P P A H P F+ A++ +++ HP + HPP + L+ PQ Sbjct: 936 IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM--PQ 993 Query: 996 SHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQ------GEQP--GQAPGFPGGADDRIP 1047 S P A P P L+ S P P HP QP Q P PGG P Sbjct: 994 SQPLPSSPAQP----PGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGP----P 1045 Query: 1048 PLPPP 1052 P+ PP Sbjct: 1046 PITPP 1050 Score = 73.2 bits (178), Expect = 1e-12 Identities = 133/610 (21%), Positives = 211/610 (34%), Gaps = 109/610 (17%) Query: 430 SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVS--DP 487 SG+ S+ + G M RS + PA S PI + +S + P +S S D Sbjct: 567 SGKHSMRTRRSRGSMSTLRSGRKKQPA--SPDGRTSPINEDIRSSGRNSPSAASTSSNDS 624 Query: 488 GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547 ++ ++ K+ + + + ++ + E A + K+ + +E+ + Sbjct: 625 KAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEAD--------RTSSKKTKTQEISR 676 Query: 548 FGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD--GLLTSEPMGSPVSSKTESVSD 605 P+S E + R + +E K++D TS + SP ++++S S Sbjct: 677 --------PNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSS 728 Query: 606 KEDK-----PPL--APSGGTEGPEQPPP---------PCPSQTGSPPVGLIKGEDKDEGP 649 + + PP AP+G T P PP P PS T PP G P Sbjct: 729 AQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQP 788 Query: 650 VAEQV--------KKSTLNPNAKEF-------NPTKPLLSVNKSTSTPTSPGPRTHSTPS 694 A + L+P +P PL + S P++P +H+ P Sbjct: 789 QAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP---SHAQP- 844 Query: 695 IPVLTAGQSGLYS------------PQYISYIPQIHMGPA---VQAPQMYPYPVSNSVPG 739 P+ G G +S PQ PQ G A YP+ S +P Sbjct: 845 -PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH-TSLQLPA 902 Query: 740 QQGKYRGAKG-------------------------SLPPQRSDQHQPASAPPMMQAAAAA 774 Q + + LP ++ +H P + P + A Sbjct: 903 SQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNAN 962 Query: 775 GPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAH-YPSQPVFAPML-QSNPRMLTSGSHPQ 832 PP A P SS ++P P + P + PS P P L QS SHP Sbjct: 963 LPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPP 1022 Query: 833 AIVSSSTPQYPSAEQP-TPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAP 891 + PQ P A+ P P + P +T PA T +QP AA Sbjct: 1023 TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP-------PAGPGTSAQPPCSGAAA 1075 Query: 892 SPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQ 951 S G + L + Q ++ +PP P PS + P A+ A ++ Sbjct: 1076 SGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYK 1135 Query: 952 QLPHGFTNMA 961 L G+ + A Sbjct: 1136 HLDRGYNSCA 1145 Score = 47.0 bits (110), Expect = 1e-04 Identities = 135/639 (21%), Positives = 209/639 (32%), Gaps = 114/639 (17%) Query: 374 PGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSP--SNRPSG 431 P L L HH ++ P P PS SP L ++ L P S+ P+G Sbjct: 967 PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPS--SPAQPPGLTQSQNLPPPPASHPPTG 1024 Query: 432 ETSVPP-PPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPG-- 488 V P PP + P P P P S PP G P +SA P + + + G Sbjct: 1025 LHQVAPQPPFAQHPFVPGGPPPITP-PTCPSTSTPPAG---PGTSAQPPCSGAAASGGSI 1080 Query: 489 VGSISPASPKISLAPTDVKELSTKE----PGRTLEPQ-----------ELARIAGKVPGL 533 G S P + + + + E P R+ P+ + AR + Sbjct: 1081 AGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRG 1140 Query: 534 QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593 N R L + G++ + + E + + +E + KEKE + E Sbjct: 1141 YNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERERER 1200 Query: 594 SPVSSKTESVSDKEDK--PPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVA 651 + S S E + P G P PPP P +G Sbjct: 1201 EAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIG------------- 1247 Query: 652 EQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP--TSPGPRTHS-----TPSIPVLTAGQSG 704 P P L + P SP R H P+ P+L G Sbjct: 1248 ----------------PDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPG 1291 Query: 705 LYSPQYISYIPQIHMGPAVQAPQMYPYPV-SNSVPGQQGKYRGAKG-SLPPQRSDQHQPA 762 LY+ + P ++ ++ + + ++ + R G + P D PA Sbjct: 1292 LYN-----------VDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPA 1340 Query: 763 SAPP--MMQAAAAAGPPLVAATPYSSYIP-YNP---QQFPGQPAMMQPMAHYPSQPVFAP 816 + P + +A PP P++S+ P NP ++ ++P YP + Sbjct: 1341 ANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAER 1400 Query: 817 MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQP- 875 + LTS + + + TP H + H + LH HQ P Sbjct: 1401 IHAERMASLTSDPLARLQMFNVTPH----------------HHQHSHIHSHLHLHQQDPL 1444 Query: 876 ---ATTPTGSQPQSQHAAP--SPVQHQAGQAPHLGSGQP---QQNLYHPGALTGTPPSL- 926 + P A P + + G P+ GQP + L HP T P L Sbjct: 1445 HQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLP 1504 Query: 927 ----PPGPSAQSPQSSFPQPAAVYAI-HHQQLPHGFTNM 960 PP +A Q+ Q A + + QQ HG +M Sbjct: 1505 GAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHGHPHM 1543 Score = 45.1 bits (105), Expect = 4e-04 Identities = 39/134 (29%), Positives = 51/134 (38%), Gaps = 32/134 (23%) Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNG-----------------GLPGPL-- 42 L PQ PS P QPP Q+ PP + PP G G P P+ Sbjct: 990 LMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITP 1049 Query: 43 ----ATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGS 98 +TS P GP +A P AA+G + G+ P P Q +E A+ Sbjct: 1050 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSS-----CPLPTVQIKEE----ALDD 1100 Query: 99 ARGQSTGKGPPQSP 112 A + PP+SP Sbjct: 1101 AEEPESPPPPPRSP 1114 Score = 41.2 bits (95), Expect = 0.005 Identities = 92/374 (24%), Positives = 125/374 (33%), Gaps = 82/374 (21%) Query: 371 GGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS 430 G P SS PP P +PGP A + P +G+ T S N+P Sbjct: 746 GVTPAPSSAPPGTPQL---PTPGPTPSATAV-------------PPQGSPTASQAPNQPQ 789 Query: 431 GETSVPPPPAVGR---MYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDP 487 T+ P + + ++P R P +P P P PP+ T SA P S + P Sbjct: 790 APTAPVPHTHIQQAPALHPQRPP---SPHPPPHPSPHPPLQPL--TGSAGQPSAPSHAQP 844 Query: 488 GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547 + P P A ++ +P L PQ G+ P + + L+ Sbjct: 845 PLHGQGPPGPHSLQAGPLLQHPGPPQP-FGLPPQ---ASQGQAPLGTSPAAAYPHTSLQL 900 Query: 548 FGAQFKLQPSSSP-ENSLDPFP-------------------PRILKEEPK---GKEKEVD 584 +Q LQ P E L P P P+ K P ++ Sbjct: 901 PASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 960 Query: 585 GLLTSEPMGSPVSSKTESVSDKEDKPPL--------------APSGGTEGPEQPPPPCPS 630 L P P+SS + PPL P G T+ PPPP Sbjct: 961 ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP--- 1017 Query: 631 QTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTH 690 PP GL + + P A+ P PT P STSTP + GP T Sbjct: 1018 -ASHPPTGL--HQVAPQPPFAQHPFVPGGPPPITP--PTCP------STSTPPA-GPGTS 1065 Query: 691 STPSIPVLTAGQSG 704 + P P A SG Sbjct: 1066 AQP--PCSGAAASG 1077 Score = 38.9 bits (89), Expect = 0.026 Identities = 38/118 (32%), Positives = 46/118 (38%), Gaps = 10/118 (8%) Query: 4 PQPLQQPSQPQQP----PPT--QQAVA---RRPPGGTSPPNGGLPGPLATSAAPPGPPAA 54 P Q P+QPQ P P T QQA A +RPP PP+ PL G P+A Sbjct: 779 PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSA 838 Query: 55 ASPCLGPVAAAG-SGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111 S P+ G G G L P PPQ P A+ + G S P + Sbjct: 839 PSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHT 896 Score = 37.0 bits (84), Expect = 0.099 Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 6/110 (5%) Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAA 65 P Q ++ QQ + + P P G P P S+APPG P +P P A A Sbjct: 716 PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP---SSAPPGTPQLPTPGPTPSATA 772 Query: 66 --GSGLRRGAEGILAPQ-PPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112 G ++ PQ P P H A A+ R S P SP Sbjct: 773 VPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP 822 Score = 36.6 bits (83), Expect = 0.13 Identities = 30/111 (27%), Positives = 38/111 (34%), Gaps = 7/111 (6%) Query: 9 QPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSG 68 QP Q P A + PPG P G P P AT+ P G P A+ P A Sbjct: 737 QPPALQAPTGVTPAPSSAPPGTPQLPTPG-PTPSATAVPPQGSPTASQAPNQPQAPTAPV 795 Query: 69 LRRGAEGILA------PQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPV 113 + A P P PP P + + GQ + Q P+ Sbjct: 796 PHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL 846 Score = 32.3 bits (72), Expect = 2.4 Identities = 33/111 (29%), Positives = 42/111 (37%), Gaps = 15/111 (13%) Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61 L P PL P + PP T P PP+ P P + +A P PPA L P Sbjct: 918 LPPAPLAMP-HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPA-----LKP 971 Query: 62 VAAAGSGLRRGAEGILAPQPPPPQ---QHQERPGAAAIGSARGQSTGKGPP 109 +++ + A PPP Q Q Q P + A QS PP Sbjct: 972 LSSLSTHHPPSA------HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 1016 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 86.7 bits (213), Expect = 1e-16 Identities = 146/545 (26%), Positives = 196/545 (35%), Gaps = 93/545 (17%) Query: 561 ENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTES-VSDKEDKPPLAPSGGTE 619 E +DP PP + K ++E DGL M + S + S + K P +P G T Sbjct: 546 EKPVDP-PPFMFKPV----KEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTS 600 Query: 620 GPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKST 679 + S SP D AE VKKS + +P K + Sbjct: 601 PINEDIRS--SGRNSPSAASTSSNDSK----AETVKKSAKKVKEEASSPLKSNKRQREKV 654 Query: 680 STPTSPGPRTHST---------PSIPVLTAGQS---------GLYSPQYISYIPQIHMGP 721 ++ T RT S P+ P G+S G P+ I + P Sbjct: 655 ASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNR-STSP 713 Query: 722 AVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAA 781 ++ +PQ +S QQ + +L P+SAPP GP Sbjct: 714 SIPSPQDNESDSDSSA--QQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP----- 766 Query: 782 TPYSSYIPYNPQQFP-GQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840 TP ++ +P PQ P A QP A P+ PV +Q P + HPQ S P Sbjct: 767 TPSATAVP--PQGSPTASQAPNQPQA--PTAPVPHTHIQQAPAL-----HPQRPPSPHPP 817 Query: 841 QYPSAEQPTPQALYATVHQSYPHHATQ-LHAHQPQPATTPTGSQPQSQHAAPS-----PV 894 +PS P + S P HA LH P P + P QH P P Sbjct: 818 PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGP-PGPHSLQAGPLLQHPGPPQPFGLPP 876 Query: 895 QHQAGQAPHLGSGQ----PQQNLYHPGALTGT----PPS---LPPGPSAQ--------SP 935 Q GQAP LG+ P +L P + + PP LPP P A +P Sbjct: 877 QASQGQAP-LGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP 935 Query: 936 QSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQ 995 P P A H P F+ A++ +++ HP + HPP + L+ PQ Sbjct: 936 IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM--PQ 993 Query: 996 SHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQ------GEQP--GQAPGFPGGADDRIP 1047 S P A P P L+ S P P HP QP Q P PGG P Sbjct: 994 SQPLPSSPAQP----PGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGP----P 1045 Query: 1048 PLPPP 1052 P+ PP Sbjct: 1046 PITPP 1050 Score = 73.2 bits (178), Expect = 1e-12 Identities = 133/610 (21%), Positives = 211/610 (34%), Gaps = 109/610 (17%) Query: 430 SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVS--DP 487 SG+ S+ + G M RS + PA S PI + +S + P +S S D Sbjct: 567 SGKHSMRTRRSRGSMSTLRSGRKKQPA--SPDGRTSPINEDIRSSGRNSPSAASTSSNDS 624 Query: 488 GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547 ++ ++ K+ + + + ++ + E A + K+ + +E+ + Sbjct: 625 KAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEAD--------RTSSKKTKTQEISR 676 Query: 548 FGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD--GLLTSEPMGSPVSSKTESVSD 605 P+S E + R + +E K++D TS + SP ++++S S Sbjct: 677 --------PNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSS 728 Query: 606 KEDK-----PPL--APSGGTEGPEQPPP---------PCPSQTGSPPVGLIKGEDKDEGP 649 + + PP AP+G T P PP P PS T PP G P Sbjct: 729 AQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQP 788 Query: 650 VAEQV--------KKSTLNPNAKEF-------NPTKPLLSVNKSTSTPTSPGPRTHSTPS 694 A + L+P +P PL + S P++P +H+ P Sbjct: 789 QAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP---SHAQP- 844 Query: 695 IPVLTAGQSGLYS------------PQYISYIPQIHMGPA---VQAPQMYPYPVSNSVPG 739 P+ G G +S PQ PQ G A YP+ S +P Sbjct: 845 -PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH-TSLQLPA 902 Query: 740 QQGKYRGAKG-------------------------SLPPQRSDQHQPASAPPMMQAAAAA 774 Q + + LP ++ +H P + P + A Sbjct: 903 SQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNAN 962 Query: 775 GPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAH-YPSQPVFAPML-QSNPRMLTSGSHPQ 832 PP A P SS ++P P + P + PS P P L QS SHP Sbjct: 963 LPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPP 1022 Query: 833 AIVSSSTPQYPSAEQP-TPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAP 891 + PQ P A+ P P + P +T PA T +QP AA Sbjct: 1023 TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP-------PAGPGTSAQPPCSGAAA 1075 Query: 892 SPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQ 951 S G + L + Q ++ +PP P PS + P A+ A ++ Sbjct: 1076 SGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYK 1135 Query: 952 QLPHGFTNMA 961 L G+ + A Sbjct: 1136 HLDRGYNSCA 1145 Score = 47.0 bits (110), Expect = 1e-04 Identities = 135/639 (21%), Positives = 209/639 (32%), Gaps = 114/639 (17%) Query: 374 PGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSP--SNRPSG 431 P L L HH ++ P P PS SP L ++ L P S+ P+G Sbjct: 967 PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPS--SPAQPPGLTQSQNLPPPPASHPPTG 1024 Query: 432 ETSVPP-PPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPG-- 488 V P PP + P P P P S PP G P +SA P + + + G Sbjct: 1025 LHQVAPQPPFAQHPFVPGGPPPITP-PTCPSTSTPPAG---PGTSAQPPCSGAAASGGSI 1080 Query: 489 VGSISPASPKISLAPTDVKELSTKE----PGRTLEPQ-----------ELARIAGKVPGL 533 G S P + + + + E P R+ P+ + AR + Sbjct: 1081 AGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRG 1140 Query: 534 QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593 N R L + G++ + + E + + +E + KEKE + E Sbjct: 1141 YNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERERER 1200 Query: 594 SPVSSKTESVSDKEDK--PPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVA 651 + S S E + P G P PPP P +G Sbjct: 1201 EAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIG------------- 1247 Query: 652 EQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP--TSPGPRTHS-----TPSIPVLTAGQSG 704 P P L + P SP R H P+ P+L G Sbjct: 1248 ----------------PDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPG 1291 Query: 705 LYSPQYISYIPQIHMGPAVQAPQMYPYPV-SNSVPGQQGKYRGAKG-SLPPQRSDQHQPA 762 LY+ + P ++ ++ + + ++ + R G + P D PA Sbjct: 1292 LYN-----------VDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPA 1340 Query: 763 SAPP--MMQAAAAAGPPLVAATPYSSYIP-YNP---QQFPGQPAMMQPMAHYPSQPVFAP 816 + P + +A PP P++S+ P NP ++ ++P YP + Sbjct: 1341 ANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAER 1400 Query: 817 MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQP- 875 + LTS + + + TP H + H + LH HQ P Sbjct: 1401 IHAERMASLTSDPLARLQMFNVTPH----------------HHQHSHIHSHLHLHQQDPL 1444 Query: 876 ---ATTPTGSQPQSQHAAP--SPVQHQAGQAPHLGSGQP---QQNLYHPGALTGTPPSL- 926 + P A P + + G P+ GQP + L HP T P L Sbjct: 1445 HQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLP 1504 Query: 927 ----PPGPSAQSPQSSFPQPAAVYAI-HHQQLPHGFTNM 960 PP +A Q+ Q A + + QQ HG +M Sbjct: 1505 GAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHGHPHM 1543 Score = 45.1 bits (105), Expect = 4e-04 Identities = 39/134 (29%), Positives = 51/134 (38%), Gaps = 32/134 (23%) Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNG-----------------GLPGPL-- 42 L PQ PS P QPP Q+ PP + PP G G P P+ Sbjct: 990 LMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITP 1049 Query: 43 ----ATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGS 98 +TS P GP +A P AA+G + G+ P P Q +E A+ Sbjct: 1050 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSS-----CPLPTVQIKEE----ALDD 1100 Query: 99 ARGQSTGKGPPQSP 112 A + PP+SP Sbjct: 1101 AEEPESPPPPPRSP 1114 Score = 41.2 bits (95), Expect = 0.005 Identities = 92/374 (24%), Positives = 125/374 (33%), Gaps = 82/374 (21%) Query: 371 GGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS 430 G P SS PP P +PGP A + P +G+ T S N+P Sbjct: 746 GVTPAPSSAPPGTPQL---PTPGPTPSATAV-------------PPQGSPTASQAPNQPQ 789 Query: 431 GETSVPPPPAVGR---MYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDP 487 T+ P + + ++P R P +P P P PP+ T SA P S + P Sbjct: 790 APTAPVPHTHIQQAPALHPQRPP---SPHPPPHPSPHPPLQPL--TGSAGQPSAPSHAQP 844 Query: 488 GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547 + P P A ++ +P L PQ G+ P + + L+ Sbjct: 845 PLHGQGPPGPHSLQAGPLLQHPGPPQP-FGLPPQ---ASQGQAPLGTSPAAAYPHTSLQL 900 Query: 548 FGAQFKLQPSSSP-ENSLDPFP-------------------PRILKEEPK---GKEKEVD 584 +Q LQ P E L P P P+ K P ++ Sbjct: 901 PASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 960 Query: 585 GLLTSEPMGSPVSSKTESVSDKEDKPPL--------------APSGGTEGPEQPPPPCPS 630 L P P+SS + PPL P G T+ PPPP Sbjct: 961 ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP--- 1017 Query: 631 QTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTH 690 PP GL + + P A+ P PT P STSTP + GP T Sbjct: 1018 -ASHPPTGL--HQVAPQPPFAQHPFVPGGPPPITP--PTCP------STSTPPA-GPGTS 1065 Query: 691 STPSIPVLTAGQSG 704 + P P A SG Sbjct: 1066 AQP--PCSGAAASG 1077 Score = 38.9 bits (89), Expect = 0.026 Identities = 38/118 (32%), Positives = 46/118 (38%), Gaps = 10/118 (8%) Query: 4 PQPLQQPSQPQQP----PPT--QQAVA---RRPPGGTSPPNGGLPGPLATSAAPPGPPAA 54 P Q P+QPQ P P T QQA A +RPP PP+ PL G P+A Sbjct: 779 PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSA 838 Query: 55 ASPCLGPVAAAG-SGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111 S P+ G G G L P PPQ P A+ + G S P + Sbjct: 839 PSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHT 896 Score = 37.0 bits (84), Expect = 0.099 Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 6/110 (5%) Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAA 65 P Q ++ QQ + + P P G P P S+APPG P +P P A A Sbjct: 716 PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP---SSAPPGTPQLPTPGPTPSATA 772 Query: 66 --GSGLRRGAEGILAPQ-PPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112 G ++ PQ P P H A A+ R S P SP Sbjct: 773 VPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP 822 Score = 36.6 bits (83), Expect = 0.13 Identities = 30/111 (27%), Positives = 38/111 (34%), Gaps = 7/111 (6%) Query: 9 QPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSG 68 QP Q P A + PPG P G P P AT+ P G P A+ P A Sbjct: 737 QPPALQAPTGVTPAPSSAPPGTPQLPTPG-PTPSATAVPPQGSPTASQAPNQPQAPTAPV 795 Query: 69 LRRGAEGILA------PQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPV 113 + A P P PP P + + GQ + Q P+ Sbjct: 796 PHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL 846 Score = 32.3 bits (72), Expect = 2.4 Identities = 33/111 (29%), Positives = 42/111 (37%), Gaps = 15/111 (13%) Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61 L P PL P + PP T P PP+ P P + +A P PPA L P Sbjct: 918 LPPAPLAMP-HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPA-----LKP 971 Query: 62 VAAAGSGLRRGAEGILAPQPPPPQ---QHQERPGAAAIGSARGQSTGKGPP 109 +++ + A PPP Q Q Q P + A QS PP Sbjct: 972 LSSLSTHHPPSA------HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 1016 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 85.1 bits (209), Expect = 3e-16 Identities = 141/529 (26%), Positives = 189/529 (35%), Gaps = 88/529 (16%) Query: 577 KGKEKEVDGLLTSEPMGSPVSSKTES-VSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSP 635 K ++E DGL M + S + S + K P +P G T + S SP Sbjct: 3 KPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRS--SGRNSP 60 Query: 636 PVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHST--- 692 D AE VKKS + +P K + ++ T RT S Sbjct: 61 SAASTSSNDSK----AETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTK 116 Query: 693 ------PSIPVLTAGQS---------GLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSV 737 P+ P G+S G P+ I + P++ +PQ +S Sbjct: 117 TQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNR-STSPSIPSPQDNESDSDSSA 175 Query: 738 PGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFP- 796 QQ + +L P+SAPP GP TP ++ +P PQ P Sbjct: 176 --QQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP-----TPSATAVP--PQGSPT 226 Query: 797 GQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYAT 856 A QP A P+ PV +Q P + HPQ S P +PS P + Sbjct: 227 ASQAPNQPQA--PTAPVPHTHIQQAPAL-----HPQRPPSPHPPPHPSPHPPLQPLTGSA 279 Query: 857 VHQSYPHHATQ-LHAHQPQPATTPTGSQPQSQHAAPS-----PVQHQAGQAPHLGSGQ-- 908 S P HA LH P P + P QH P P Q GQAP LG+ Sbjct: 280 GQPSAPSHAQPPLHGQGP-PGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAP-LGTSPAA 337 Query: 909 --PQQNLYHPGALTGT----PPS---LPPGPSAQ--------SPQSSFPQPAAVYAIHHQ 951 P +L P + + PP LPP P A +P P P A H Sbjct: 338 AYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHL 397 Query: 952 QLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVP 1011 P F+ A++ +++ HP + HPP + L+ PQS P A P P Sbjct: 398 SGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM--PQSQPLPSSPAQP----P 451 Query: 1012 ALSASTPSPYPYIGHPQ------GEQP--GQAPGFPGGADDRIPPLPPP 1052 L+ S P P HP QP Q P PGG PP+ PP Sbjct: 452 GLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGP----PPITPP 496 Score = 73.2 bits (178), Expect = 1e-12 Identities = 133/610 (21%), Positives = 211/610 (34%), Gaps = 109/610 (17%) Query: 430 SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVS--DP 487 SG+ S+ + G M RS + PA S PI + +S + P +S S D Sbjct: 13 SGKHSMRTRRSRGSMSTLRSGRKKQPA--SPDGRTSPINEDIRSSGRNSPSAASTSSNDS 70 Query: 488 GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547 ++ ++ K+ + + + ++ + E A + K+ + +E+ + Sbjct: 71 KAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEAD--------RTSSKKTKTQEISR 122 Query: 548 FGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD--GLLTSEPMGSPVSSKTESVSD 605 P+S E + R + +E K++D TS + SP ++++S S Sbjct: 123 --------PNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSS 174 Query: 606 KEDK-----PPL--APSGGTEGPEQPPP---------PCPSQTGSPPVGLIKGEDKDEGP 649 + + PP AP+G T P PP P PS T PP G P Sbjct: 175 AQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQP 234 Query: 650 VAEQV--------KKSTLNPNAKEF-------NPTKPLLSVNKSTSTPTSPGPRTHSTPS 694 A + L+P +P PL + S P++P +H+ P Sbjct: 235 QAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP---SHAQP- 290 Query: 695 IPVLTAGQSGLYS------------PQYISYIPQIHMGPA---VQAPQMYPYPVSNSVPG 739 P+ G G +S PQ PQ G A YP+ S +P Sbjct: 291 -PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH-TSLQLPA 348 Query: 740 QQGKYRGAKG-------------------------SLPPQRSDQHQPASAPPMMQAAAAA 774 Q + + LP ++ +H P + P + A Sbjct: 349 SQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNAN 408 Query: 775 GPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAH-YPSQPVFAPML-QSNPRMLTSGSHPQ 832 PP A P SS ++P P + P + PS P P L QS SHP Sbjct: 409 LPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPP 468 Query: 833 AIVSSSTPQYPSAEQP-TPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAP 891 + PQ P A+ P P + P +T PA T +QP AA Sbjct: 469 TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP-------PAGPGTSAQPPCSGAAA 521 Query: 892 SPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQ 951 S G + L + Q ++ +PP P PS + P A+ A ++ Sbjct: 522 SGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYK 581 Query: 952 QLPHGFTNMA 961 L G+ + A Sbjct: 582 HLDRGYNSCA 591 Score = 47.0 bits (110), Expect = 1e-04 Identities = 135/639 (21%), Positives = 209/639 (32%), Gaps = 114/639 (17%) Query: 374 PGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSP--SNRPSG 431 P L L HH ++ P P PS SP L ++ L P S+ P+G Sbjct: 413 PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPS--SPAQPPGLTQSQNLPPPPASHPPTG 470 Query: 432 ETSVPP-PPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPG-- 488 V P PP + P P P P S PP G P +SA P + + + G Sbjct: 471 LHQVAPQPPFAQHPFVPGGPPPITP-PTCPSTSTPPAG---PGTSAQPPCSGAAASGGSI 526 Query: 489 VGSISPASPKISLAPTDVKELSTKE----PGRTLEPQ-----------ELARIAGKVPGL 533 G S P + + + + E P R+ P+ + AR + Sbjct: 527 AGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRG 586 Query: 534 QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593 N R L + G++ + + E + + +E + KEKE + E Sbjct: 587 YNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERERER 646 Query: 594 SPVSSKTESVSDKEDK--PPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVA 651 + S S E + P G P PPP P +G Sbjct: 647 EAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIG------------- 693 Query: 652 EQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP--TSPGPRTHS-----TPSIPVLTAGQSG 704 P P L + P SP R H P+ P+L G Sbjct: 694 ----------------PDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPG 737 Query: 705 LYSPQYISYIPQIHMGPAVQAPQMYPYPV-SNSVPGQQGKYRGAKG-SLPPQRSDQHQPA 762 LY+ + P ++ ++ + + ++ + R G + P D PA Sbjct: 738 LYN-----------VDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPA 786 Query: 763 SAPP--MMQAAAAAGPPLVAATPYSSYIP-YNP---QQFPGQPAMMQPMAHYPSQPVFAP 816 + P + +A PP P++S+ P NP ++ ++P YP + Sbjct: 787 ANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAER 846 Query: 817 MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQP- 875 + LTS + + + TP H + H + LH HQ P Sbjct: 847 IHAERMASLTSDPLARLQMFNVTPH----------------HHQHSHIHSHLHLHQQDPL 890 Query: 876 ---ATTPTGSQPQSQHAAP--SPVQHQAGQAPHLGSGQP---QQNLYHPGALTGTPPSL- 926 + P A P + + G P+ GQP + L HP T P L Sbjct: 891 HQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLP 950 Query: 927 ----PPGPSAQSPQSSFPQPAAVYAI-HHQQLPHGFTNM 960 PP +A Q+ Q A + + QQ HG +M Sbjct: 951 GAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHGHPHM 989 Score = 45.1 bits (105), Expect = 4e-04 Identities = 39/134 (29%), Positives = 51/134 (38%), Gaps = 32/134 (23%) Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNG-----------------GLPGPL-- 42 L PQ PS P QPP Q+ PP + PP G G P P+ Sbjct: 436 LMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITP 495 Query: 43 ----ATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGS 98 +TS P GP +A P AA+G + G+ P P Q +E A+ Sbjct: 496 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSS-----CPLPTVQIKEE----ALDD 546 Query: 99 ARGQSTGKGPPQSP 112 A + PP+SP Sbjct: 547 AEEPESPPPPPRSP 560 Score = 41.2 bits (95), Expect = 0.005 Identities = 92/374 (24%), Positives = 125/374 (33%), Gaps = 82/374 (21%) Query: 371 GGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS 430 G P SS PP P +PGP A + P +G+ T S N+P Sbjct: 192 GVTPAPSSAPPGTPQL---PTPGPTPSATAV-------------PPQGSPTASQAPNQPQ 235 Query: 431 GETSVPPPPAVGR---MYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDP 487 T+ P + + ++P R P +P P P PP+ T SA P S + P Sbjct: 236 APTAPVPHTHIQQAPALHPQRPP---SPHPPPHPSPHPPLQPL--TGSAGQPSAPSHAQP 290 Query: 488 GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547 + P P A ++ +P L PQ G+ P + + L+ Sbjct: 291 PLHGQGPPGPHSLQAGPLLQHPGPPQP-FGLPPQ---ASQGQAPLGTSPAAAYPHTSLQL 346 Query: 548 FGAQFKLQPSSSP-ENSLDPFP-------------------PRILKEEPK---GKEKEVD 584 +Q LQ P E L P P P+ K P ++ Sbjct: 347 PASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 406 Query: 585 GLLTSEPMGSPVSSKTESVSDKEDKPPL--------------APSGGTEGPEQPPPPCPS 630 L P P+SS + PPL P G T+ PPPP Sbjct: 407 ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP--- 463 Query: 631 QTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTH 690 PP GL + + P A+ P PT P STSTP + GP T Sbjct: 464 -ASHPPTGL--HQVAPQPPFAQHPFVPGGPPPITP--PTCP------STSTPPA-GPGTS 511 Query: 691 STPSIPVLTAGQSG 704 + P P A SG Sbjct: 512 AQP--PCSGAAASG 523 Score = 38.9 bits (89), Expect = 0.026 Identities = 38/118 (32%), Positives = 46/118 (38%), Gaps = 10/118 (8%) Query: 4 PQPLQQPSQPQQP----PPT--QQAVA---RRPPGGTSPPNGGLPGPLATSAAPPGPPAA 54 P Q P+QPQ P P T QQA A +RPP PP+ PL G P+A Sbjct: 225 PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSA 284 Query: 55 ASPCLGPVAAAG-SGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111 S P+ G G G L P PPQ P A+ + G S P + Sbjct: 285 PSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHT 342 Score = 37.0 bits (84), Expect = 0.099 Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 6/110 (5%) Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAA 65 P Q ++ QQ + + P P G P P S+APPG P +P P A A Sbjct: 162 PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP---SSAPPGTPQLPTPGPTPSATA 218 Query: 66 --GSGLRRGAEGILAPQ-PPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112 G ++ PQ P P H A A+ R S P SP Sbjct: 219 VPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP 268 Score = 36.6 bits (83), Expect = 0.13 Identities = 30/111 (27%), Positives = 38/111 (34%), Gaps = 7/111 (6%) Query: 9 QPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSG 68 QP Q P A + PPG P G P P AT+ P G P A+ P A Sbjct: 183 QPPALQAPTGVTPAPSSAPPGTPQLPTPG-PTPSATAVPPQGSPTASQAPNQPQAPTAPV 241 Query: 69 LRRGAEGILA------PQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPV 113 + A P P PP P + + GQ + Q P+ Sbjct: 242 PHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL 292 Score = 32.3 bits (72), Expect = 2.4 Identities = 33/111 (29%), Positives = 42/111 (37%), Gaps = 15/111 (13%) Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61 L P PL P + PP T P PP+ P P + +A P PPA L P Sbjct: 364 LPPAPLAMP-HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPA-----LKP 417 Query: 62 VAAAGSGLRRGAEGILAPQPPPPQ---QHQERPGAAAIGSARGQSTGKGPP 109 +++ + A PPP Q Q Q P + A QS PP Sbjct: 418 LSSLSTHHPPSA------HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 462 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 80.9 bits (198), Expect = 6e-15 Identities = 168/701 (23%), Positives = 242/701 (34%), Gaps = 168/701 (23%) Query: 375 GLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETS 434 GL++ G SP + G+ S++S + +R + A +S P G S Sbjct: 15 GLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQI--AAVMSRAQGLPKG--S 70 Query: 435 VPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISP 494 VPP A SP + +S P P S P DPG P Sbjct: 71 VPPAAA-------ESPSMHRKQELDSSHP--------PKQSGRPP------DPG----RP 105 Query: 495 ASPKISLA-PTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKF----G 549 A P +S + TD K PGR+ P ++ L+ + R L+E K G Sbjct: 106 AQPGLSKSRTTDTFRSEQKLPGRS--PSTIS--------LKESKSRTDLKEEHKSSMMPG 155 Query: 550 AQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKED- 608 ++ S+ + ++ F P L + + ++E ++K + V KE Sbjct: 156 FLSEVNALSAVSSVVNKFNPFDLISDSEASQEE--------------TTKKQKVVQKEQG 201 Query: 609 ------KPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPN 662 KPPL +QPP P P Q G G D P+ + +++ Sbjct: 202 KPEGIIKPPLQ--------QQPPKPIPKQQG-------PGRD----PLQQDGTPKSISSQ 242 Query: 663 AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722 E ++P K PT H+ +P+ Q + PQ Sbjct: 243 QPEKIKSQP-PGTGKPIQGPTQTPQTDHA--KLPL-----------QRDASRPQTKQADI 288 Query: 723 VQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAAT 782 V+ + P S S P Q G + P ++ QP A P Q + P +A Sbjct: 289 VRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGH-EKSQPGPAKPPAQPSGLTKP--LAQQ 345 Query: 783 PYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQY 842 P + P P PG ++P P+ + P +GS + Sbjct: 346 PGTVKPPVQP---PG-----------TTKPPAQPLGPAKPPAQQTGS-----------EK 380 Query: 843 PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAG-QA 901 PS+EQP P+AL + P + A QP PA PT Q P P+ Q G Q+ Sbjct: 381 PSSEQPGPKAL------AQPPGVGKTPAQQPGPAKPPT-----QQVGTPKPLAQQPGLQS 429 Query: 902 PHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMA 961 P G + + PG G P+ GP S Q + P QLP Sbjct: 430 PAKAPGPTKTPVQQPG--PGKIPAQQAGPGKTSAQQTGPTKPP------SQLP------G 475 Query: 962 HVTQAHVQTGITAAPPPHPGAPHPP--QVMLLHPPQSHGGPPQGAVPQSGVPALSASTPS 1019 Q G PP PG+ PP Q PP GP + + Q G S PS Sbjct: 476 PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPG----STKPPS 531 Query: 1020 PYPYIGHPQGEQPGQAPGFPGGADDRIP--------PLPPP 1052 P P +QP +P P P PL PP Sbjct: 532 QQPGSAKPSAQQP--SPAKPSAQQSTKPVSQTGSGKPLQPP 570 Score = 68.9 bits (167), Expect = 2e-11 Identities = 157/690 (22%), Positives = 231/690 (33%), Gaps = 123/690 (17%) Query: 333 QGSGRESPSLASREGKYIPLPQRVREGPR---GGVRCSSSRGG-------RPGLSSLPPR 382 Q +G E PS K + P V + P G + + + G +PGL S P + Sbjct: 374 QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQS-PAK 432 Query: 383 --GPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGET--SVPPP 438 GP PGPG + GP + S + P + L P+ P + + PPP Sbjct: 433 APGPTKTPVQQPGPG-KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPP 491 Query: 439 PAVGRMYPP-----------RSPKSAAPAPISASCPEPPI---GSAVPTSSASIPV---- 480 G PP + P A P+P +PP GSA P++ P Sbjct: 492 QQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSA 551 Query: 481 ---TSSVSDPGVG------SISPAS--------PK--ISLAPTDVKELSTKEPGRTLEPQ 521 T VS G G ++SP++ PK L T L E Sbjct: 552 QQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCT 611 Query: 522 ELARIAGKVPGLQNEQKRFQLEELRKFGAQFK------LQP-SSSPENSLDPFP----PR 570 E + G +++E Q K L P SSP+ L P Sbjct: 612 ECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSA 671 Query: 571 ILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEG-----PEQPP 625 + K P+ ++ TS + + + PPL G +QPP Sbjct: 672 VSKSSPQPQQ-------TSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724 Query: 626 PPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSP 685 +PP ++D+ PVA+ K K PT L+S + +T+ P P Sbjct: 725 EADSLSKPAPPKEPSVPSEQDKAPVADDKPK-----QPKMVKPTTDLVSSSSATTKPDIP 779 Query: 686 GPRTHS------TPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPG 739 + S TP + +A S + P P A+ P +S+ PG Sbjct: 780 SSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSP--FDSKAIPRPASDSKIISH--PG 835 Query: 740 QQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQP 799 + +G K P Q+ + +P A M A P P S P P+ GQ Sbjct: 836 PSSESKGQKQVDPVQKKE--EPKKAQTKMSPKPDAKP-----MPKGSPTPPGPRPTAGQT 888 Query: 800 AMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQ 859 + P + QS L GS ++ + P+ Q T Sbjct: 889 VPTPQQSPKPQE-------QSRRFSLNLGS-----ITDAPKSQPTTPQETVTGKLFGFGA 936 Query: 860 SYPHHATQL--HAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPG 917 S A+ L A QP P + P Q AP+P Q Q P +GQ Sbjct: 937 SIFSQASNLISTAGQPGPHSQSGPGAPMKQ--APAPSQPPTSQGPPKSTGQ--------- 985 Query: 918 ALTGTPPSLPPGPSAQSPQSSFPQPAAVYA 947 A S+P ++P + +P A A Sbjct: 986 APPAPAKSIPVKKETKAPAAEKLEPKAEQA 1015 Score = 58.5 bits (140), Expect = 3e-08 Identities = 149/691 (21%), Positives = 211/691 (30%), Gaps = 135/691 (19%) Query: 405 PSRMSPKAQRPLRG-----AKTLSSPSNRPSGETSVPP---PPAVGRMYPPRSPKSAAPA 456 P + PK Q P R S S +P S PP P G P++ + P Sbjct: 215 PPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPL 274 Query: 457 PISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGR 516 AS P+ V S P S S P + +P P + + +P Sbjct: 275 QRDASRPQTKQADIVRGESVK-PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP-- 331 Query: 517 TLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEP 576 +P L + + PG + Q K AQ L P+ P P + P Sbjct: 332 PAQPSGLTKPLAQQPG--TVKPPVQPPGTTKPPAQ-PLGPAKPPAQQTGSEKPSSEQPGP 388 Query: 577 KGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPP 636 K + T P T+ V + PLA G + P + P P + P Sbjct: 389 KALAQPPGVGKTPAQQPGPAKPPTQQVGTPK---PLAQQPGLQSPAKAPGPTKTPVQQPG 445 Query: 637 VGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIP 696 G I + G +A++ PTKP + PGP Sbjct: 446 PGKIPAQQAGPG-----------KTSAQQTGPTKPPSQL---------PGP--------- 476 Query: 697 VLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRS 756 + P GPA PQ P S P QQ GS P Sbjct: 477 ---------------AKPPPQQPGPAKPPPQQ---PGSAKPPSQQ------PGSTKP--- 509 Query: 757 DQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAP 816 QP A P Q + PP QP +P A PS + Sbjct: 510 PPQQPGPAKPSPQQPGSTKPP------------------SQQPGSAKPSAQQPSPAKPSA 551 Query: 817 MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPA 876 + P T P + S PSA+QP Q L T+ + T+L H P+ A Sbjct: 552 QQSTKPVSQTGSGKPLQPPTVS----PSAKQPPSQGLPKTICPLC--NTTELLLHVPEKA 605 Query: 877 TTPTGSQPQSQHAA-----PSPVQHQAGQ----------------APHLGSGQPQQNLYH 915 T ++ Q+ + P+P + + AP S QP+ Sbjct: 606 NFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKT-A 664 Query: 916 PGALTGTPPSLPPGPSAQSPQ---------SSFPQPAAVYAIHHQQLPHGFTNMAHVTQA 966 P T P P SP+ S P+P + Q HG + Sbjct: 665 PVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724 Query: 967 HVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGH 1026 + APP P P P + P Q + + +S+S+ + P I Sbjct: 725 EADSLSKPAPPKEPSVPSEQD----KAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS 780 Query: 1027 PQGEQPGQAPGFPGGADDRIPP---LPPPGE 1054 + + + P D P PP GE Sbjct: 781 SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGE 811 Score = 55.1 bits (131), Expect = 4e-07 Identities = 99/449 (22%), Positives = 159/449 (35%), Gaps = 78/449 (17%) Query: 373 RPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGE 432 +P L + P + SSP P + + P + KA P + + P+ S Sbjct: 658 QPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPS 717 Query: 433 TSVPPPPAVGRMYPPRSPKSAA------PAPISASCPEPPIGSAVPTSSASIPVTSSVSD 486 PP + P PK + AP++ P+ P V ++ + +S+ + Sbjct: 718 AKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQP--KMVKPTTDLVSSSSATTK 775 Query: 487 PGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELR 546 P + S S +K S K P ++ P E++ Sbjct: 776 PDIPSSKVQSQAEEKTTPPLKTDSAK-PSQSFPPTG--------------------EKVS 814 Query: 547 KFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDK 606 F ++ +P+S + P P E KG +K+VD + E P ++T+ +S K Sbjct: 815 PFDSKAIPRPASDSKIISHPGP----SSESKG-QKQVDPVQKKE---EPKKAQTK-MSPK 865 Query: 607 EDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN----PN 662 D P+ P G P PP P T V + K + EQ ++ +LN + Sbjct: 866 PDAKPM-PKG------SPTPPGPRPTAGQTVPTPQQSPKPQ----EQSRRFSLNLGSITD 914 Query: 663 AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722 A + PT P +V T G S S + TAGQ G +S P Sbjct: 915 APKSQPTTPQETV---TGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG-------APM 964 Query: 723 VQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPAS---------APPMMQAAAA 773 QAP P S P G+ A P + + PA+ AP + + Sbjct: 965 KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETE 1024 Query: 774 AGPPLV------AATPYSSYIPYNPQQFP 796 PP + A P + +P ++ P Sbjct: 1025 KKPPPIKDSKSLTAEPQKAVLPTKLEKSP 1053 Score = 51.2 bits (121), Expect = 5e-06 Identities = 42/119 (35%), Positives = 53/119 (44%), Gaps = 17/119 (14%) Query: 6 PLQQPSQPQQPPPTQQAVARRP----PGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61 P QQP + PPTQQ +P PG SP PGP T PGP + GP Sbjct: 401 PAQQPGPAK--PPTQQVGTPKPLAQQPGLQSPAKA--PGPTKTPVQQPGPGKIPAQQAGP 456 Query: 62 --VAAAGSGLRRGAEGILAPQPPPPQQ------HQERPGAAAIGSARGQSTGKGPPQSP 112 +A +G + + P PPPQQ ++PG+A S + ST K PPQ P Sbjct: 457 GKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGST-KPPPQQP 514 Score = 44.7 bits (104), Expect = 5e-04 Identities = 39/119 (32%), Positives = 45/119 (37%), Gaps = 30/119 (25%) Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPP--NGGLPGPLA----TSAAPPGPPAAASPCL 59 P+QQP+ P +PP Q + PG PP GL PLA T P PP P Sbjct: 305 PIQQPT-PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363 Query: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQ------HQERPGAAAIGSARGQSTGKGPPQSP 112 P L P PP QQ E+PG A+ G GK P Q P Sbjct: 364 QP---------------LGPAKPPAQQTGSEKPSSEQPGPKALAQPPG--VGKTPAQQP 405 Score = 39.3 bits (90), Expect = 0.020 Identities = 34/101 (33%), Positives = 41/101 (40%), Gaps = 16/101 (15%) Query: 3 KPQPLQQPSQPQQPPPTQQAVARRP---PGGTSPPNGGLPGPLATSAAPPGPPAAASPCL 59 KP P QQP P +PPP Q A+ P PG T PP PGP S PG + P Sbjct: 478 KPPP-QQPG-PAKPPPQQPGSAKPPSQQPGSTKPPPQQ-PGPAKPSPQQPG--STKPPSQ 532 Query: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSAR 100 P +A S + P P P Q + GS + Sbjct: 533 QPGSAKPSAQQ--------PSPAKPSAQQSTKPVSQTGSGK 565 Score = 37.7 bits (86), Expect = 0.058 Identities = 31/83 (37%), Positives = 38/83 (45%), Gaps = 8/83 (9%) Query: 6 PLQQPSQPQQPPPTQQAVAR---RPPGGTSPPNGGLPGPLATSAAPPGP-PAAASPCLGP 61 P QQP + PPP Q A+ + PG T PP+ PG SA P P +A P Sbjct: 500 PSQQPGSTK-PPPQQPGPAKPSPQQPGSTKPPS-QQPGSAKPSAQQPSPAKPSAQQSTKP 557 Query: 62 VAAAGSG--LRRGAEGILAPQPP 82 V+ GSG L+ A QPP Sbjct: 558 VSQTGSGKPLQPPTVSPSAKQPP 580 Score = 36.6 bits (83), Expect = 0.13 Identities = 36/112 (32%), Positives = 45/112 (40%), Gaps = 13/112 (11%) Query: 6 PLQQPSQ---PQQPPPTQQAVARRPP--GGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 P + PSQ P +PPP Q A+ PP G++ P PG PG PA SP Sbjct: 466 PTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPG-PAKPSP-QQ 523 Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112 P + + G+ A QP P +P A Q TG G P P Sbjct: 524 PGSTKPPSQQPGSAKPSAQQPSP-----AKPSAQQSTKPVSQ-TGSGKPLQP 569 Score = 35.4 bits (80), Expect = 0.29 Identities = 34/114 (29%), Positives = 46/114 (40%), Gaps = 12/114 (10%) Query: 4 PQPLQQPSQPQQPP--PTQQA----VARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASP 57 P P + P Q P P QQA + + G T PP+ LPGP PGP A P Sbjct: 434 PGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ-LPGPAKPPPQQPGP--AKPP 490 Query: 58 CLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111 P +A + G+ QP P + ++PG+ S Q G P + Sbjct: 491 PQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS---QQPGSAKPSA 541 Score = 35.4 bits (80), Expect = 0.29 Identities = 61/265 (23%), Positives = 101/265 (38%), Gaps = 51/265 (19%) Query: 390 SSPGPGSEARGINGGPSRMSP--KAQRPLRGAKTLS-SPSNRPSGETSVPPP---PAVGR 443 S PGP SE++G ++ P K + P + +S P +P + S PP P G+ Sbjct: 832 SHPGPSSESKG----QKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQ 887 Query: 444 MYPP--RSPK-------------SAAPAPISA-SCPEPPIGSAVPTSSASI-----PVTS 482 P +SPK S AP S + P+ + + ASI + S Sbjct: 888 TVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947 Query: 483 SVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQL 542 + PG S S + AP + +++ P ++ G+ P K + Sbjct: 948 TAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKS---------TGQAPPAP--AKSIPV 996 Query: 543 EELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGL--LTSEPMGSPVSSKT 600 ++ K A KL+P + P + + E + K + LT+EP + + +K Sbjct: 997 KKETKAPAAEKLEPKAEQA-------PTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKL 1049 Query: 601 ESVSDKEDKPPLAPSGGTEGPEQPP 625 E E PL + G + PP Sbjct: 1050 EKSPKPESTCPLCKTELNIGSKDPP 1074 Score = 34.7 bits (78), Expect = 0.49 Identities = 37/128 (28%), Positives = 47/128 (36%), Gaps = 28/128 (21%) Query: 3 KPQPLQQPSQP--------QQP----PPTQQAVARRPP----GGTSPPNGGLPGPLATSA 46 +P P + P+QP QQP PP Q +PP G PP G S+ Sbjct: 325 QPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP-AQQTGSEKPSS 383 Query: 47 APPGPPAAAS-PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTG 105 PGP A A P +G A G P PP QQ A + + Sbjct: 384 EQPGPKALAQPPGVGKTPAQQPG----------PAKPPTQQVGTPKPLAQQPGLQSPAKA 433 Query: 106 KGPPQSPV 113 GP ++PV Sbjct: 434 PGPTKTPV 441 Score = 31.2 bits (69), Expect = 5.4 Identities = 36/138 (26%), Positives = 48/138 (34%), Gaps = 15/138 (10%) Query: 575 EPKGKEKEVDGLLTSEPMGSPV---------SSKTESVSDKEDKPPLAPSGGTEGPEQPP 625 E G+EK L + P S + SS + + PP P P PP Sbjct: 2365 ETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPP 2424 Query: 626 PPCPSQTGSPPVGLIKGEDKDEGPVAEQV----KKSTLNPNAKEFNPTKPLLSVNKSTST 681 PP P T P L K + PV +TL A + P+ + T+ Sbjct: 2425 PPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRI--CTTA 2482 Query: 682 PTSPGPRTHSTPSIPVLT 699 P P+ S PS V T Sbjct: 2483 PPPVPPKPSSIPSGLVFT 2500 Score = 30.4 bits (67), Expect = 9.2 Identities = 28/122 (22%), Positives = 53/122 (43%), Gaps = 11/122 (9%) Query: 533 LQNEQKRFQLEELRKFGAQFKLQP---SSSPENSLDPFPPRILKEEPKGKEKEVDGLLTS 589 +++E+K+ LEE + KL P +S+PE +LK + + E++++G + Sbjct: 1227 IRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHD----LLKSQVQIAEEKLEGRVAP 1282 Query: 590 EPMGSPVSSKTESVSDKEDKPPLAPSGGTEGP----EQPPPPCPSQTGSPPVGLIKGEDK 645 + + +T+ P P + EQP PPC ++ G K E + Sbjct: 1283 KTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKE 1342 Query: 646 DE 647 D+ Sbjct: 1343 DD 1344 Score = 30.4 bits (67), Expect = 9.2 Identities = 38/155 (24%), Positives = 57/155 (36%), Gaps = 18/155 (11%) Query: 534 QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593 + E K+ + R G SS E L +LKE+ K +E E Sbjct: 1749 KGESKQQRKARHRPHGPLLPTIEDSSEEEELRE-EEELLKEQEKQREIEQQ--------- 1798 Query: 594 SPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP-CPSQTGSPPVGLIKGEDKDE---GP 649 K+ S K+DK L E P+ PP P + SP L + + +E Sbjct: 1799 ---QRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSS 1855 Query: 650 VAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTS 684 +E +P E +P K ++ V K PT+ Sbjct: 1856 CSEYSPSIESDPEGFEISPEK-IIEVQKVYKLPTA 1889 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 80.9 bits (198), Expect = 6e-15 Identities = 168/701 (23%), Positives = 242/701 (34%), Gaps = 168/701 (23%) Query: 375 GLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETS 434 GL++ G SP + G+ S++S + +R + A +S P G S Sbjct: 15 GLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQI--AAVMSRAQGLPKG--S 70 Query: 435 VPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISP 494 VPP A SP + +S P P S P DPG P Sbjct: 71 VPPAAA-------ESPSMHRKQELDSSHP--------PKQSGRPP------DPG----RP 105 Query: 495 ASPKISLA-PTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKF----G 549 A P +S + TD K PGR+ P ++ L+ + R L+E K G Sbjct: 106 AQPGLSKSRTTDTFRSEQKLPGRS--PSTIS--------LKESKSRTDLKEEHKSSMMPG 155 Query: 550 AQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKED- 608 ++ S+ + ++ F P L + + ++E ++K + V KE Sbjct: 156 FLSEVNALSAVSSVVNKFNPFDLISDSEASQEE--------------TTKKQKVVQKEQG 201 Query: 609 ------KPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPN 662 KPPL +QPP P P Q G G D P+ + +++ Sbjct: 202 KPEGIIKPPLQ--------QQPPKPIPKQQG-------PGRD----PLQQDGTPKSISSQ 242 Query: 663 AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722 E ++P K PT H+ +P+ Q + PQ Sbjct: 243 QPEKIKSQP-PGTGKPIQGPTQTPQTDHA--KLPL-----------QRDASRPQTKQADI 288 Query: 723 VQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAAT 782 V+ + P S S P Q G + P ++ QP A P Q + P +A Sbjct: 289 VRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGH-EKSQPGPAKPPAQPSGLTKP--LAQQ 345 Query: 783 PYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQY 842 P + P P PG ++P P+ + P +GS + Sbjct: 346 PGTVKPPVQP---PG-----------TTKPPAQPLGPAKPPAQQTGS-----------EK 380 Query: 843 PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAG-QA 901 PS+EQP P+AL + P + A QP PA PT Q P P+ Q G Q+ Sbjct: 381 PSSEQPGPKAL------AQPPGVGKTPAQQPGPAKPPT-----QQVGTPKPLAQQPGLQS 429 Query: 902 PHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMA 961 P G + + PG G P+ GP S Q + P QLP Sbjct: 430 PAKAPGPTKTPVQQPG--PGKIPAQQAGPGKTSAQQTGPTKPP------SQLP------G 475 Query: 962 HVTQAHVQTGITAAPPPHPGAPHPP--QVMLLHPPQSHGGPPQGAVPQSGVPALSASTPS 1019 Q G PP PG+ PP Q PP GP + + Q G S PS Sbjct: 476 PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPG----STKPPS 531 Query: 1020 PYPYIGHPQGEQPGQAPGFPGGADDRIP--------PLPPP 1052 P P +QP +P P P PL PP Sbjct: 532 QQPGSAKPSAQQP--SPAKPSAQQSTKPVSQTGSGKPLQPP 570 Score = 68.9 bits (167), Expect = 2e-11 Identities = 157/690 (22%), Positives = 231/690 (33%), Gaps = 123/690 (17%) Query: 333 QGSGRESPSLASREGKYIPLPQRVREGPR---GGVRCSSSRGG-------RPGLSSLPPR 382 Q +G E PS K + P V + P G + + + G +PGL S P + Sbjct: 374 QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQS-PAK 432 Query: 383 --GPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGET--SVPPP 438 GP PGPG + GP + S + P + L P+ P + + PPP Sbjct: 433 APGPTKTPVQQPGPG-KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPP 491 Query: 439 PAVGRMYPP-----------RSPKSAAPAPISASCPEPPI---GSAVPTSSASIPV---- 480 G PP + P A P+P +PP GSA P++ P Sbjct: 492 QQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSA 551 Query: 481 ---TSSVSDPGVG------SISPAS--------PK--ISLAPTDVKELSTKEPGRTLEPQ 521 T VS G G ++SP++ PK L T L E Sbjct: 552 QQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCT 611 Query: 522 ELARIAGKVPGLQNEQKRFQLEELRKFGAQFK------LQP-SSSPENSLDPFP----PR 570 E + G +++E Q K L P SSP+ L P Sbjct: 612 ECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSA 671 Query: 571 ILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEG-----PEQPP 625 + K P+ ++ TS + + + PPL G +QPP Sbjct: 672 VSKSSPQPQQ-------TSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724 Query: 626 PPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSP 685 +PP ++D+ PVA+ K K PT L+S + +T+ P P Sbjct: 725 EADSLSKPAPPKEPSVPSEQDKAPVADDKPK-----QPKMVKPTTDLVSSSSATTKPDIP 779 Query: 686 GPRTHS------TPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPG 739 + S TP + +A S + P P A+ P +S+ PG Sbjct: 780 SSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSP--FDSKAIPRPASDSKIISH--PG 835 Query: 740 QQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQP 799 + +G K P Q+ + +P A M A P P S P P+ GQ Sbjct: 836 PSSESKGQKQVDPVQKKE--EPKKAQTKMSPKPDAKP-----MPKGSPTPPGPRPTAGQT 888 Query: 800 AMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQ 859 + P + QS L GS ++ + P+ Q T Sbjct: 889 VPTPQQSPKPQE-------QSRRFSLNLGS-----ITDAPKSQPTTPQETVTGKLFGFGA 936 Query: 860 SYPHHATQL--HAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPG 917 S A+ L A QP P + P Q AP+P Q Q P +GQ Sbjct: 937 SIFSQASNLISTAGQPGPHSQSGPGAPMKQ--APAPSQPPTSQGPPKSTGQ--------- 985 Query: 918 ALTGTPPSLPPGPSAQSPQSSFPQPAAVYA 947 A S+P ++P + +P A A Sbjct: 986 APPAPAKSIPVKKETKAPAAEKLEPKAEQA 1015 Score = 58.5 bits (140), Expect = 3e-08 Identities = 149/691 (21%), Positives = 211/691 (30%), Gaps = 135/691 (19%) Query: 405 PSRMSPKAQRPLRG-----AKTLSSPSNRPSGETSVPP---PPAVGRMYPPRSPKSAAPA 456 P + PK Q P R S S +P S PP P G P++ + P Sbjct: 215 PPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPL 274 Query: 457 PISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGR 516 AS P+ V S P S S P + +P P + + +P Sbjct: 275 QRDASRPQTKQADIVRGESVK-PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP-- 331 Query: 517 TLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEP 576 +P L + + PG + Q K AQ L P+ P P + P Sbjct: 332 PAQPSGLTKPLAQQPG--TVKPPVQPPGTTKPPAQ-PLGPAKPPAQQTGSEKPSSEQPGP 388 Query: 577 KGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPP 636 K + T P T+ V + PLA G + P + P P + P Sbjct: 389 KALAQPPGVGKTPAQQPGPAKPPTQQVGTPK---PLAQQPGLQSPAKAPGPTKTPVQQPG 445 Query: 637 VGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIP 696 G I + G +A++ PTKP + PGP Sbjct: 446 PGKIPAQQAGPG-----------KTSAQQTGPTKPPSQL---------PGP--------- 476 Query: 697 VLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRS 756 + P GPA PQ P S P QQ GS P Sbjct: 477 ---------------AKPPPQQPGPAKPPPQQ---PGSAKPPSQQ------PGSTKP--- 509 Query: 757 DQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAP 816 QP A P Q + PP QP +P A PS + Sbjct: 510 PPQQPGPAKPSPQQPGSTKPP------------------SQQPGSAKPSAQQPSPAKPSA 551 Query: 817 MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPA 876 + P T P + S PSA+QP Q L T+ + T+L H P+ A Sbjct: 552 QQSTKPVSQTGSGKPLQPPTVS----PSAKQPPSQGLPKTICPLC--NTTELLLHVPEKA 605 Query: 877 TTPTGSQPQSQHAA-----PSPVQHQAGQ----------------APHLGSGQPQQNLYH 915 T ++ Q+ + P+P + + AP S QP+ Sbjct: 606 NFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKT-A 664 Query: 916 PGALTGTPPSLPPGPSAQSPQ---------SSFPQPAAVYAIHHQQLPHGFTNMAHVTQA 966 P T P P SP+ S P+P + Q HG + Sbjct: 665 PVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724 Query: 967 HVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGH 1026 + APP P P P + P Q + + +S+S+ + P I Sbjct: 725 EADSLSKPAPPKEPSVPSEQD----KAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS 780 Query: 1027 PQGEQPGQAPGFPGGADDRIPP---LPPPGE 1054 + + + P D P PP GE Sbjct: 781 SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGE 811 Score = 55.1 bits (131), Expect = 4e-07 Identities = 99/449 (22%), Positives = 159/449 (35%), Gaps = 78/449 (17%) Query: 373 RPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGE 432 +P L + P + SSP P + + P + KA P + + P+ S Sbjct: 658 QPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPS 717 Query: 433 TSVPPPPAVGRMYPPRSPKSAA------PAPISASCPEPPIGSAVPTSSASIPVTSSVSD 486 PP + P PK + AP++ P+ P V ++ + +S+ + Sbjct: 718 AKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQP--KMVKPTTDLVSSSSATTK 775 Query: 487 PGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELR 546 P + S S +K S K P ++ P E++ Sbjct: 776 PDIPSSKVQSQAEEKTTPPLKTDSAK-PSQSFPPTG--------------------EKVS 814 Query: 547 KFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDK 606 F ++ +P+S + P P E KG +K+VD + E P ++T+ +S K Sbjct: 815 PFDSKAIPRPASDSKIISHPGP----SSESKG-QKQVDPVQKKE---EPKKAQTK-MSPK 865 Query: 607 EDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN----PN 662 D P+ P G P PP P T V + K + EQ ++ +LN + Sbjct: 866 PDAKPM-PKG------SPTPPGPRPTAGQTVPTPQQSPKPQ----EQSRRFSLNLGSITD 914 Query: 663 AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722 A + PT P +V T G S S + TAGQ G +S P Sbjct: 915 APKSQPTTPQETV---TGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG-------APM 964 Query: 723 VQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPAS---------APPMMQAAAA 773 QAP P S P G+ A P + + PA+ AP + + Sbjct: 965 KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETE 1024 Query: 774 AGPPLV------AATPYSSYIPYNPQQFP 796 PP + A P + +P ++ P Sbjct: 1025 KKPPPIKDSKSLTAEPQKAVLPTKLEKSP 1053 Score = 51.2 bits (121), Expect = 5e-06 Identities = 42/119 (35%), Positives = 53/119 (44%), Gaps = 17/119 (14%) Query: 6 PLQQPSQPQQPPPTQQAVARRP----PGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61 P QQP + PPTQQ +P PG SP PGP T PGP + GP Sbjct: 401 PAQQPGPAK--PPTQQVGTPKPLAQQPGLQSPAKA--PGPTKTPVQQPGPGKIPAQQAGP 456 Query: 62 --VAAAGSGLRRGAEGILAPQPPPPQQ------HQERPGAAAIGSARGQSTGKGPPQSP 112 +A +G + + P PPPQQ ++PG+A S + ST K PPQ P Sbjct: 457 GKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGST-KPPPQQP 514 Score = 44.7 bits (104), Expect = 5e-04 Identities = 39/119 (32%), Positives = 45/119 (37%), Gaps = 30/119 (25%) Query: 6 PLQQPSQPQQPPPTQQAVARRPPGGTSPP--NGGLPGPLA----TSAAPPGPPAAASPCL 59 P+QQP+ P +PP Q + PG PP GL PLA T P PP P Sbjct: 305 PIQQPT-PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363 Query: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQ------HQERPGAAAIGSARGQSTGKGPPQSP 112 P L P PP QQ E+PG A+ G GK P Q P Sbjct: 364 QP---------------LGPAKPPAQQTGSEKPSSEQPGPKALAQPPG--VGKTPAQQP 405 Score = 39.3 bits (90), Expect = 0.020 Identities = 34/101 (33%), Positives = 41/101 (40%), Gaps = 16/101 (15%) Query: 3 KPQPLQQPSQPQQPPPTQQAVARRP---PGGTSPPNGGLPGPLATSAAPPGPPAAASPCL 59 KP P QQP P +PPP Q A+ P PG T PP PGP S PG + P Sbjct: 478 KPPP-QQPG-PAKPPPQQPGSAKPPSQQPGSTKPPPQQ-PGPAKPSPQQPG--STKPPSQ 532 Query: 60 GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSAR 100 P +A S + P P P Q + GS + Sbjct: 533 QPGSAKPSAQQ--------PSPAKPSAQQSTKPVSQTGSGK 565 Score = 37.7 bits (86), Expect = 0.058 Identities = 31/83 (37%), Positives = 38/83 (45%), Gaps = 8/83 (9%) Query: 6 PLQQPSQPQQPPPTQQAVAR---RPPGGTSPPNGGLPGPLATSAAPPGP-PAAASPCLGP 61 P QQP + PPP Q A+ + PG T PP+ PG SA P P +A P Sbjct: 500 PSQQPGSTK-PPPQQPGPAKPSPQQPGSTKPPS-QQPGSAKPSAQQPSPAKPSAQQSTKP 557 Query: 62 VAAAGSG--LRRGAEGILAPQPP 82 V+ GSG L+ A QPP Sbjct: 558 VSQTGSGKPLQPPTVSPSAKQPP 580 Score = 36.6 bits (83), Expect = 0.13 Identities = 36/112 (32%), Positives = 45/112 (40%), Gaps = 13/112 (11%) Query: 6 PLQQPSQ---PQQPPPTQQAVARRPP--GGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 P + PSQ P +PPP Q A+ PP G++ P PG PG PA SP Sbjct: 466 PTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPG-PAKPSP-QQ 523 Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112 P + + G+ A QP P +P A Q TG G P P Sbjct: 524 PGSTKPPSQQPGSAKPSAQQPSP-----AKPSAQQSTKPVSQ-TGSGKPLQP 569 Score = 35.4 bits (80), Expect = 0.29 Identities = 34/114 (29%), Positives = 46/114 (40%), Gaps = 12/114 (10%) Query: 4 PQPLQQPSQPQQPP--PTQQA----VARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASP 57 P P + P Q P P QQA + + G T PP+ LPGP PGP A P Sbjct: 434 PGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ-LPGPAKPPPQQPGP--AKPP 490 Query: 58 CLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111 P +A + G+ QP P + ++PG+ S Q G P + Sbjct: 491 PQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS---QQPGSAKPSA 541 Score = 35.4 bits (80), Expect = 0.29 Identities = 61/265 (23%), Positives = 101/265 (38%), Gaps = 51/265 (19%) Query: 390 SSPGPGSEARGINGGPSRMSP--KAQRPLRGAKTLS-SPSNRPSGETSVPPP---PAVGR 443 S PGP SE++G ++ P K + P + +S P +P + S PP P G+ Sbjct: 832 SHPGPSSESKG----QKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQ 887 Query: 444 MYPP--RSPK-------------SAAPAPISA-SCPEPPIGSAVPTSSASI-----PVTS 482 P +SPK S AP S + P+ + + ASI + S Sbjct: 888 TVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947 Query: 483 SVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQL 542 + PG S S + AP + +++ P ++ G+ P K + Sbjct: 948 TAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKS---------TGQAPPAP--AKSIPV 996 Query: 543 EELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGL--LTSEPMGSPVSSKT 600 ++ K A KL+P + P + + E + K + LT+EP + + +K Sbjct: 997 KKETKAPAAEKLEPKAEQA-------PTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKL 1049 Query: 601 ESVSDKEDKPPLAPSGGTEGPEQPP 625 E E PL + G + PP Sbjct: 1050 EKSPKPESTCPLCKTELNIGSKDPP 1074 Score = 34.7 bits (78), Expect = 0.49 Identities = 37/128 (28%), Positives = 47/128 (36%), Gaps = 28/128 (21%) Query: 3 KPQPLQQPSQP--------QQP----PPTQQAVARRPP----GGTSPPNGGLPGPLATSA 46 +P P + P+QP QQP PP Q +PP G PP G S+ Sbjct: 325 QPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP-AQQTGSEKPSS 383 Query: 47 APPGPPAAAS-PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTG 105 PGP A A P +G A G P PP QQ A + + Sbjct: 384 EQPGPKALAQPPGVGKTPAQQPG----------PAKPPTQQVGTPKPLAQQPGLQSPAKA 433 Query: 106 KGPPQSPV 113 GP ++PV Sbjct: 434 PGPTKTPV 441 Score = 31.2 bits (69), Expect = 5.4 Identities = 36/138 (26%), Positives = 48/138 (34%), Gaps = 15/138 (10%) Query: 575 EPKGKEKEVDGLLTSEPMGSPV---------SSKTESVSDKEDKPPLAPSGGTEGPEQPP 625 E G+EK L + P S + SS + + PP P P PP Sbjct: 2365 ETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPP 2424 Query: 626 PPCPSQTGSPPVGLIKGEDKDEGPVAEQV----KKSTLNPNAKEFNPTKPLLSVNKSTST 681 PP P T P L K + PV +TL A + P+ + T+ Sbjct: 2425 PPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRI--CTTA 2482 Query: 682 PTSPGPRTHSTPSIPVLT 699 P P+ S PS V T Sbjct: 2483 PPPVPPKPSSIPSGLVFT 2500 Score = 30.4 bits (67), Expect = 9.2 Identities = 28/122 (22%), Positives = 53/122 (43%), Gaps = 11/122 (9%) Query: 533 LQNEQKRFQLEELRKFGAQFKLQP---SSSPENSLDPFPPRILKEEPKGKEKEVDGLLTS 589 +++E+K+ LEE + KL P +S+PE +LK + + E++++G + Sbjct: 1227 IRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHD----LLKSQVQIAEEKLEGRVAP 1282 Query: 590 EPMGSPVSSKTESVSDKEDKPPLAPSGGTEGP----EQPPPPCPSQTGSPPVGLIKGEDK 645 + + +T+ P P + EQP PPC ++ G K E + Sbjct: 1283 KTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKE 1342 Query: 646 DE 647 D+ Sbjct: 1343 DD 1344 Score = 30.4 bits (67), Expect = 9.2 Identities = 38/155 (24%), Positives = 57/155 (36%), Gaps = 18/155 (11%) Query: 534 QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593 + E K+ + R G SS E L +LKE+ K +E E Sbjct: 1749 KGESKQQRKARHRPHGPLLPTIEDSSEEEELRE-EEELLKEQEKQREIEQQ--------- 1798 Query: 594 SPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP-CPSQTGSPPVGLIKGEDKDE---GP 649 K+ S K+DK L E P+ PP P + SP L + + +E Sbjct: 1799 ---QRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSS 1855 Query: 650 VAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTS 684 +E +P E +P K ++ V K PT+ Sbjct: 1856 CSEYSPSIESDPEGFEISPEK-IIEVQKVYKLPTA 1889 >gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] Length = 416 Score = 79.7 bits (195), Expect = 1e-14 Identities = 120/487 (24%), Positives = 156/487 (32%), Gaps = 116/487 (23%) Query: 580 EKEVDGLLTSEPMGSPVS--SKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPV 637 ++E L+ P G+P +K + KP P G P+ PPPP G PP Sbjct: 25 QEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP- 83 Query: 638 GLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPV 697 +G +K +GP + K +P P P P P+ + P P Sbjct: 84 ---QGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP-------PGKPQGPPPQGGNQPQGPP 133 Query: 698 LTAGQSGLYSPQYISYIPQIHMGPAVQA---PQMYPYPVSNSVPGQQGKYRGAKGSLPPQ 754 G+ PQ GP Q PQ P P GK +G PPQ Sbjct: 134 PPPGK------------PQ---GPPPQGGNKPQGPPPP---------GKPQGP----PPQ 165 Query: 755 RSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVF 814 ++ + + +PP GPP P P P PG+P P Q Sbjct: 166 GDNKSRSSRSPP----GKPQGPP-----PQGGNQPQGPPPPPGKPQGPPPQGGNKPQ--- 213 Query: 815 APMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQ 874 P P+ G PQ S + + P + P Q P + PQ Sbjct: 214 GPPPPGKPQ----GPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 269 Query: 875 PATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQS 934 P G P + P P ++ G+PQ P G P PP P + Sbjct: 270 GGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQG----PPPQGGNQPQGPPPPPGK- 324 Query: 935 PQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGA--------PHPP 986 PQ PQ + Q G PPP G+ P P Sbjct: 325 PQGPPPQGG------------------NKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKP 366 Query: 987 QVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRI 1046 Q PPQ G PQG P +G G+PQ Q A G P G Sbjct: 367 Q----GPPQQEGNNPQGPPPPAG---------------GNPQQPQAPPA-GQPQG----- 401 Query: 1047 PPLPPPG 1053 PP PP G Sbjct: 402 PPRPPQG 408 Score = 77.4 bits (189), Expect = 7e-14 Identities = 116/429 (27%), Positives = 135/429 (31%), Gaps = 62/429 (14%) Query: 650 VAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQ--SGLYS 707 VA S N N P L P G + PS P G G Sbjct: 8 VALLALSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQ 67 Query: 708 PQYISYIPQIHMGPAVQA---PQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASA 764 PQ P GP Q PQ P P GK +G PPQ P S Sbjct: 68 PQGPPPPPGKPQGPPPQGGNKPQGPPPP---------GKPQGP----PPQGDKSRSPRSP 114 Query: 765 PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRM 824 P Q GPP P P P PG+P P Q P P+ Sbjct: 115 PGKPQ-----GPP-----PQGGNQPQGPPPPPGKPQGPPPQGGNKPQ---GPPPPGKPQ- 160 Query: 825 LTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQP 884 G PQ S + + P + P Q P + PQ P G P Sbjct: 161 ---GPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 217 Query: 885 QSQHAAPSPVQHQAGQA-----------PHLGSGQPQQNLYHPGALTGTPP---SLPPGP 930 + P P Q+ P G QPQ PG G PP + P GP Sbjct: 218 PGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP 277 Query: 931 SAQS-PQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVM 989 PQ P P + P G + G PPP PG P P Sbjct: 278 PPPGKPQG--PPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQG----PPPPPGKPQGPPPQ 331 Query: 990 LLHPPQSHGGP--PQGAVPQSGVPALSASTPSPYPYIGHPQ--GEQPGQAPGFPGGADDR 1045 + PQ P PQG PQ G + SA +P P G PQ G P Q P P G + + Sbjct: 332 GGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQ-GPPQQEGNNP-QGPPPPAGGNPQ 389 Query: 1046 IPPLPPPGE 1054 P PP G+ Sbjct: 390 QPQAPPAGQ 398 Score = 73.6 bits (179), Expect = 1e-12 Identities = 102/393 (25%), Positives = 128/393 (32%), Gaps = 67/393 (17%) Query: 555 QPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSS-KTESVSDKEDKPPLA 613 QP P P P + P+G K +P G P K+ S KP Sbjct: 67 QPQGPP-----PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGP 121 Query: 614 PSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLL 673 P G P+ PPPP G PP +G +K +GP P K P P Sbjct: 122 PPQGGNQPQGPPPPPGKPQGPPP----QGGNKPQGP----------PPPGKPQGP--PPQ 165 Query: 674 SVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQA---PQMYP 730 NKS S+ + PG P G PQ P GP Q PQ P Sbjct: 166 GDNKSRSSRSPPGKPQGPPP---------QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 216 Query: 731 YPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPY 790 P GK +G PPQ ++ Q A +PP GPP P P Sbjct: 217 PP---------GKPQGP----PPQGDNKSQSARSPP----GKPQGPP-----PQGGNQPQ 254 Query: 791 NPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTP 850 P PG+P P Q P P+ G PQ S + + P + P Sbjct: 255 GPPPPPGKPQGPPPQGGNKPQ---GPPPPGKPQ----GPPPQGGSKSRSSRSPPGKPQGP 307 Query: 851 QALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQ 910 Q P + PQ P G P + P P ++ G+PQ Sbjct: 308 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQ 367 Query: 911 QNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPA 943 P G P PP P+ +PQ PA Sbjct: 368 ----GPPQQEGNNPQGPPPPAGGNPQQPQAPPA 396 Score = 64.7 bits (156), Expect = 4e-10 Identities = 109/435 (25%), Positives = 140/435 (32%), Gaps = 57/435 (13%) Query: 335 SGRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGP 394 S ESPSL + + P PQ + P+G G P P+GP GP Sbjct: 24 SQEESPSLIAGNPQGAP-PQGGNK-PQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 81 Query: 395 GSEARGINGGPSRMSPKAQRPLRGAKTLS--SPSNRPSGET--------SVPPPPAVGRM 444 + GP P +G K+ S SP +P G PPPP + Sbjct: 82 PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 141 Query: 445 YPPRSP-KSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAP 503 PP+ K P P PP G SS S P P G+ P P Sbjct: 142 PPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKP 201 Query: 504 TDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFG--AQFKLQPSSSPE 561 +P P + G P N+ + + + G Q QP P Sbjct: 202 QGPPPQGGNKP---QGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPP- 257 Query: 562 NSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPV--SSKTESVSDKEDKPPLAPSGGTE 619 P P + P+G K +P G P SK+ S KP P G Sbjct: 258 ----PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGN 313 Query: 620 GPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKST 679 P+ PPPP G PP +G +K +GP P KP Sbjct: 314 QPQGPPPPPGKPQGPPP----QGGNKPQGPPP----------------PGKP-------Q 346 Query: 680 STPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPG 739 P G ++ S S P G PQ PQ PA PQ P + G Sbjct: 347 GPPPQGGSKSRSARSPPGKPQG-----PPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQG 401 Query: 740 QQGKYRGAKGSLPPQ 754 +G + S PPQ Sbjct: 402 PPRPPQGGRPSRPPQ 416 Score = 61.2 bits (147), Expect = 5e-09 Identities = 104/431 (24%), Positives = 134/431 (31%), Gaps = 57/431 (13%) Query: 394 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSA 453 P A G P + K Q P P + + PPPP PP + Sbjct: 29 PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 88 Query: 454 APAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKE 513 P P+ P + S P P G P P P K Sbjct: 89 PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP----PPPPGKPQGPPP 144 Query: 514 PG--RTLEPQELARIAGKVPGLQNEQKRFQLEELRKFG--AQFKLQPSSSPENSLDPFPP 569 G + P + G P N+ + + + G Q QP P P P Sbjct: 145 QGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPP-----PPPG 199 Query: 570 RILKEEPKGKEKEVDGLLTSEPMGSPV--SSKTESVSDKEDKPPLAPSGGTEGPEQPPPP 627 + P+G K +P G P +K++S KP P G P+ PPPP Sbjct: 200 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPP 259 Query: 628 CPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGP 687 G PP +G +K +GP P K P P +KS S+ + PG Sbjct: 260 PGKPQGPPP----QGGNKPQGP----------PPPGKPQGP--PPQGGSKSRSSRSPPGK 303 Query: 688 RTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQA---PQMYPYPVSNSVPGQQGKY 744 P G PQ P GP Q PQ P P P QG Sbjct: 304 PQGPPP---------QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGS 354 Query: 745 RGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFP-GQP--AM 801 + PP + PP + GPP P + P PQ P GQP Sbjct: 355 KSRSARSPPGK------PQGPPQQEGNNPQGPP-----PPAGGNPQQPQAPPAGQPQGPP 403 Query: 802 MQPMAHYPSQP 812 P PS+P Sbjct: 404 RPPQGGRPSRP 414 Score = 48.9 bits (115), Expect = 3e-05 Identities = 42/131 (32%), Positives = 49/131 (37%), Gaps = 25/131 (19%) Query: 3 KPQPLQQPSQPQQPPP---TQQAVARRPPG--------GTSPPNGGLPGPLATSAAPP-- 49 KPQ P +PQ PPP + AR PPG G + P G P P PP Sbjct: 211 KPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 270 Query: 50 -----GPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQE------RPGAAAIGS 98 GPP P GP GS R PQ PPPQ + PG Sbjct: 271 GNKPQGPPPPGKP-QGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 329 Query: 99 ARGQSTGKGPP 109 +G + +GPP Sbjct: 330 PQGGNKPQGPP 340 Score = 48.5 bits (114), Expect = 3e-05 Identities = 42/131 (32%), Positives = 50/131 (38%), Gaps = 22/131 (16%) Query: 3 KPQPLQQPSQPQQPPP---TQQAVARRPPG--------GTSPPNGGLPGPLATSAAPP-- 49 KPQ P +PQ PPP ++ +R PPG G + P G P P PP Sbjct: 273 KPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 332 Query: 50 -----GPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQ---HQERPGAAAIGSARG 101 GPP P GP GS R PQ PP Q+ Q P A + Sbjct: 333 GNKPQGPPPPGKP-QGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQP 391 Query: 102 QSTGKGPPQSP 112 Q+ G PQ P Sbjct: 392 QAPPAGQPQGP 402 Score = 47.8 bits (112), Expect = 6e-05 Identities = 40/133 (30%), Positives = 51/133 (38%), Gaps = 19/133 (14%) Query: 3 KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLP-----GP-------LATSAAP 48 KPQ P Q +QPQ PPP PP G + P G P GP ++ +P Sbjct: 179 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSP 238 Query: 49 PG-----PPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQS 103 PG PP + GP G +G PQ PPP + P +R Sbjct: 239 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSR 298 Query: 104 TGKGPPQSPVFEG 116 + G PQ P +G Sbjct: 299 SPPGKPQGPPPQG 311 Score = 47.4 bits (111), Expect = 7e-05 Identities = 40/133 (30%), Positives = 51/133 (38%), Gaps = 19/133 (14%) Query: 3 KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLP-----GP-------LATSAAP 48 KPQ P Q +QPQ PPP PP G + P G P GP +S +P Sbjct: 117 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSP 176 Query: 49 PG-----PPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQS 103 PG PP + GP G +G PQ PPP + P ++ Sbjct: 177 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSAR 236 Query: 104 TGKGPPQSPVFEG 116 + G PQ P +G Sbjct: 237 SPPGKPQGPPPQG 249 Score = 45.4 bits (106), Expect = 3e-04 Identities = 45/131 (34%), Positives = 54/131 (41%), Gaps = 23/131 (17%) Query: 3 KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLP-----GP-------LATSAAP 48 KPQ P Q +QPQ PPP PP G + P G P GP +S +P Sbjct: 241 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP 300 Query: 49 PG-----PPAAASPCLGPVAAAGSGLRRGAEGILAPQ-PPPPQQHQERP--GAAAIGSAR 100 PG PP + GP G +G PQ PPPP + Q P G + SAR Sbjct: 301 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSAR 360 Query: 101 G-QSTGKGPPQ 110 +GPPQ Sbjct: 361 SPPGKPQGPPQ 371 Score = 45.1 bits (105), Expect = 4e-04 Identities = 35/109 (32%), Positives = 42/109 (38%), Gaps = 12/109 (11%) Query: 3 KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 KPQ P Q +QPQ PPP PP G + P G P P GPP Sbjct: 56 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP-----PGKPQGPPPQGDKSRS 110 Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109 P + G +G PQ PPP PG +G + +GPP Sbjct: 111 PRSPPGKPQGPPPQGGNQPQGPPPP-----PGKPQGPPPQGGNKPQGPP 154 Score = 44.3 bits (103), Expect = 6e-04 Identities = 37/117 (31%), Positives = 47/117 (40%), Gaps = 16/117 (13%) Query: 3 KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPG-----PPAAA 55 KPQ P Q ++PQ PPP +P G PP GG +S +PPG PP Sbjct: 262 KPQGPPPQGGNKPQGPPP-----PGKPQG--PPPQGG--SKSRSSRSPPGKPQGPPPQGG 312 Query: 56 SPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112 + GP G +G PQ PPP + P +R + G PQ P Sbjct: 313 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGP 369 Score = 43.1 bits (100), Expect = 0.001 Identities = 39/130 (30%), Positives = 47/130 (36%), Gaps = 24/130 (18%) Query: 3 KPQPLQQPSQPQQPPPT--QQAVARRPPG--------GTSPPNGGLPGPLATSAAPP--- 49 KPQ P +PQ PPP + R PPG G + P G P P PP Sbjct: 88 KPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 147 Query: 50 ----GPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQE------RPGAAAIGSA 99 GPP P GP + R PQ PPPQ + PG Sbjct: 148 NKPQGPPPPGKP-QGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 206 Query: 100 RGQSTGKGPP 109 +G + +GPP Sbjct: 207 QGGNKPQGPP 216 Score = 37.0 bits (84), Expect = 0.099 Identities = 32/105 (30%), Positives = 39/105 (37%), Gaps = 9/105 (8%) Query: 13 PQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRG 72 PQ PP + PP P G P P + P GPP GP G +G Sbjct: 36 PQGAPPQGGNKPQGPPSPPGKPQG--PPPQGGN-QPQGPPPPPGKPQGP-PPQGGNKPQG 91 Query: 73 AEGILAPQPPPPQQHQER-----PGAAAIGSARGQSTGKGPPQSP 112 PQ PPPQ + R PG +G + +GPP P Sbjct: 92 PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP 136 Score = 31.6 bits (70), Expect = 4.2 Identities = 21/61 (34%), Positives = 24/61 (39%), Gaps = 12/61 (19%) Query: 3 KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 KPQ P Q+ + PQ PP PP G +P P P PP PP P Sbjct: 365 KPQGPPQQEGNNPQGPP---------PPAGGNPQQPQAP-PAGQPQGPPRPPQGGRPSRP 414 Query: 61 P 61 P Sbjct: 415 P 415 >gi|55750053 atrophin-1 [Homo sapiens] Length = 1190 Score = 78.2 bits (191), Expect = 4e-14 Identities = 147/626 (23%), Positives = 209/626 (33%), Gaps = 116/626 (18%) Query: 490 GSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEEL---R 546 G SP +S + +D K +++ + +E + G E + EE + Sbjct: 31 GRASPGG--VSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPK 88 Query: 547 KFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD--GLLTSEPMGSPVSSKTESVS 604 K + +L SP + LD R L ++ +++D TS + SP S + +S S Sbjct: 89 KTKTEQELPRPQSPSD-LDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDS 147 Query: 605 DKEDKPPLAPSGGTEGPEQP--PPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPN 662 SG ++GP +P PPP + PP + P A ++ P Sbjct: 148 S---------SGLSQGPARPYHPPPLFPPSPQPP------DSTPRQPEASFEPHPSVTPT 192 Query: 663 AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722 P + ++ P P+ + + VL+ G S + + G Sbjct: 193 GYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQ 252 Query: 723 VQAPQMYPYPVSNSVPGQQGKYR----------GAKGSLPPQRSDQHQPASAPPMMQAA- 771 P P+S S G G G S PP + H + PP Sbjct: 253 HPPPTT---PISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRP 309 Query: 772 ---AAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRML--- 825 A+A PP + A P P P AM Q M P P P L +P L Sbjct: 310 LNNASASPPGLGAQPL-------PGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPA 362 Query: 826 -------------TSGSHPQAIVSSSTPQYPSAEQPTP--QALYATVHQSYPHHATQLHA 870 +S S A SSS+ S+ P P QAL SYPH Sbjct: 363 SSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQAL-----PSYPHSF----- 412 Query: 871 HQPQPATTPTGSQPQ--SQHAAPSPVQHQAGQAPHLGSGQPQQNLY-HPGALTGTPPSLP 927 P P + +QP +Q + PS G P G+ N HPG Sbjct: 413 --PPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPG---------- 460 Query: 928 PGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQ 987 P P + QS+ P + + HHQQ Q Q + PPP PHP + Sbjct: 461 PFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLE 520 Query: 988 VMLLH------------------PPQSHGGPPQGAVPQS-----GVPALSASTPSPYPYI 1024 H P +H PP V S G P S+S S Sbjct: 521 GGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQ 580 Query: 1025 GHPQGEQPGQAPGFPGGADDRIPPLP 1050 G P + G P GA PP+P Sbjct: 581 GSYPCSHPSPSQG-PQGAPYPFPPVP 605 Score = 70.9 bits (172), Expect = 6e-12 Identities = 165/706 (23%), Positives = 230/706 (32%), Gaps = 108/706 (15%) Query: 391 SPGPGSEARGIN----GGPSRMSP--KAQRPLRGAKTL-----SSPSNRPSGETSVPPPP 439 +PGP E R GG S S KA++ + AK S+P G + Sbjct: 20 APGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISES 79 Query: 440 AVGRMYPPRSPKSAA--PAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPA-- 495 P+ K+ P P S S + G ++ +S P D S SP+ Sbjct: 80 ESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDI---DQDNRSTSPSIY 136 Query: 496 SPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQ 555 SP +D ++ P R P L + + P Q E Sbjct: 137 SPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHA 196 Query: 556 PSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSD----KEDKPP 611 P P + + PP P+ G+L+ PMG SV K+ PP Sbjct: 197 PMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPP 256 Query: 612 LAP-SGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTK 670 P S + G PP P T PVG G + P T N P Sbjct: 257 TTPISVSSSGASGAPPTKPPTT---PVG---GGNLPSAPPPANFPHVTPN-----LPPPP 305 Query: 671 PLLSVNKSTSTPTSPG--PRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQ-APQ 727 L +N ++++P G P PS + G GL P GP + +P Sbjct: 306 ALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLP--------PGPEKGPTLAPSPH 357 Query: 728 MYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSY 787 P P S+S P PP R +S+ +++++ + P S Sbjct: 358 SLP-PASSSAPA------------PPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQA 404 Query: 788 IPYNPQQFPGQPAM----MQPMAHYPSQPVFAPMLQSNP------RMLT-SGSHPQAIVS 836 +P P FP ++ P PS P A Q P R+L S +HP Sbjct: 405 LPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPP 464 Query: 837 SSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQ- 895 S+ Q S P P + + HQ Q Q Q S P A P P++ Sbjct: 465 STGAQ--STAHP-PVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEG 521 Query: 896 ------HQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQ--PAAVYA 947 H +P LGS +P Y PG P LPP S S + P P + + Sbjct: 522 GSSHHAHPYAMSPSLGSLRP----YPPG-----PAHLPPPHSQVSYSQAGPNGPPVSSSS 572 Query: 948 IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQ 1007 G +H + + G AP P P P + Sbjct: 573 NSSSSTSQGSYPCSHPSPSQ---GPQGAPYPFPPVPTVTT---------------SSATL 614 Query: 1008 SGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRIPPLPPPG 1053 S V A AS+P+ Y P G+ PG PP PG Sbjct: 615 STVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPG 660 Score = 65.1 bits (157), Expect = 3e-10 Identities = 146/633 (23%), Positives = 197/633 (31%), Gaps = 114/633 (18%) Query: 371 GGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS 430 GG G+ S PP GP G S G NGG P + + +P +P Sbjct: 222 GGTGGVLSGPPMGP-----KGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKP- 275 Query: 431 GETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVG 490 P VG P +P A ++ + P PP + +SAS P + PG Sbjct: 276 ------PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPG-- 327 Query: 491 SISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGA 550 P+ + + K P P L + P RF A Sbjct: 328 -HLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPA---PPMRFPYSSSSSSSA 383 Query: 551 QFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKP 610 SSS +S PFP L S P P P Sbjct: 384 AAS-SSSSSSSSSASPFP--------------ASQALPSYPHSFP--------------P 414 Query: 611 PLAPSGGTEGPEQPPPPCPSQT----GSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEF 666 P + S + P+ P PSQ G PP P + S +P Sbjct: 415 PTSLSVSNQPPKYTQPSLPSQAVWSQGPPP----------PPPYGRLLANSNAHP----- 459 Query: 667 NPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAP 726 P P + P S H Q Q Q H P Sbjct: 460 GPFPPSTGAQSTAHPPVSTHHHHHQQQQ-------QQQQQQQQQQQQQQQHHGNSGPPPP 512 Query: 727 QMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPP-----MMQAAAAAGPPLVAA 781 +P+P+ Y SL R PA PP A GPP+ ++ Sbjct: 513 GAFPHPLEGGSSHHAHPY-AMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSS 571 Query: 782 TPYSSYIPYN--PQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSST 839 + SS P P P+ A YP PV P + ++ L S A V+SS Sbjct: 572 SNSSSSTSQGSYPCSHP-SPSQGPQGAPYPFPPV--PTVTTSSATL---STVIATVASSP 625 Query: 840 PQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAG 899 Y +A P P P + + + TP G +P SP + G Sbjct: 626 AGYKTASPPGP-----------PPYGKRAPSPGAYKTATPPGYKP------GSPPSFRTG 668 Query: 900 QAP-HLGSGQPQ-QNLYHPGALTGTPPSLPP-GPSAQSPQSSFPQPAAVYAIHHQQLPHG 956 P + G+ P + PG+ T P LPP GPS S P P A A P Sbjct: 669 TPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSG---LPSLPPPPAAPA---SGPPLS 722 Query: 957 FTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVM 989 T + +T + PP +P PP+V+ Sbjct: 723 ATQIKQEPAEEYETPESPVPPARSPSP-PPKVV 754 Score = 60.1 bits (144), Expect = 1e-08 Identities = 131/564 (23%), Positives = 178/564 (31%), Gaps = 123/564 (21%) Query: 359 GPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNS----SPGPGSEARGINGG---------- 404 GP+GG SS G G PP P + +S +P + GG Sbjct: 234 GPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPAN 293 Query: 405 -----PSRMSPKAQRPLRGAKT-------------LSSPSNRPSGETSVPPPPAVGRMYP 446 P+ P A RPL A L SP G +PP P G Sbjct: 294 FPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLA 353 Query: 447 PRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDV 506 P SP S PA S+S P PP+ P +SS S S S +S S +P Sbjct: 354 P-SPHSLPPA--SSSAPAPPM---------RFPYSSSSSSSAAASSSSSSSSSSASPFPA 401 Query: 507 KELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSL-- 564 + P P L+ + N+ ++ L + P P L Sbjct: 402 SQALPSYPHSFPPPTSLS--------VSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLA 453 Query: 565 ------DPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSS-----KTESVSDKEDKPPLA 613 PFPP T+ P PVS+ + + ++ + Sbjct: 454 NSNAHPGPFPP------------STGAQSTAHP---PVSTHHHHHQQQQQQQQQQQQQQQ 498 Query: 614 PSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLL 673 G PPPP G+ P L G P A +L P P P Sbjct: 499 QQQQHHGNSGPPPP-----GAFPHPLEGGSSHHAHPYAMSPSLGSLRP-----YPPGP-- 546 Query: 674 SVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP- 732 P S + + P+ P +++ + S SY P H P+ Q PQ PYP Sbjct: 547 ---AHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSY-PCSHPSPS-QGPQGAPYPF 601 Query: 733 ------------VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAG----- 775 +S + G K + PP + A +P + A G Sbjct: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS 661 Query: 776 -PPLVAATP---YSSYIPYNPQQF-PGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSH 830 P TP + P P F PG P + P P+ P P L P SG Sbjct: 662 PPSFRTGTPPGYRGTSPPAGPGTFKPGSPT-VGPGPLPPAGPSGLPSLPPPPAAPASGPP 720 Query: 831 PQAIVSSSTP--QYPSAEQPTPQA 852 A P +Y + E P P A Sbjct: 721 LSATQIKQEPAEEYETPESPVPPA 744 Score = 40.8 bits (94), Expect = 0.007 Identities = 133/590 (22%), Positives = 201/590 (34%), Gaps = 102/590 (17%) Query: 351 PLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSP 410 P P R G + ++ G +PG P +P PG GP P Sbjct: 636 PPPYGKRAPSPGAYKTATPPGYKPG-------SPPSFRTGTP-PGYRGTSPPAGPGTFKP 687 Query: 411 KAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKS------------AAPAPI 458 + P G L P PSG S+PPPPA PP S +P P Sbjct: 688 GS--PTVGPGPL--PPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPP 743 Query: 459 SASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRT- 517 + S PP VP+ ++ + D G S A + P + +L+ K Sbjct: 744 ARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSC--ARSDLYFVPLEGSKLAKKRADLVE 801 Query: 518 ---LEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKL-QPSSSPEN--SLDPFPPRI 571 E ++ AR + + +K + E+ R+ KL Q +P SL P P R Sbjct: 802 KVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRP 861 Query: 572 LKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPC--P 629 E + T P P + ++S+ +P + G P P P Sbjct: 862 PFEPG-------SAVATVPPYLGPDTPALRTLSEYA-RPHVMSPGNRNHPFYVPLGAVDP 913 Query: 630 SQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTS--PGP 687 G L + P A + ++ + ++ KP V S P PGP Sbjct: 914 GLLGYNVPALYSSD-----PAAREREREARERDLRD--RLKPGFEVKPSELEPLHGVPGP 966 Query: 688 RTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQ--APQMYPYPVSNSV-PGQQGKY 744 P H G A+Q P ++P+P S+ P ++ + Sbjct: 967 GLDPFPR-----------------------HGGLALQPGPPGLHPFPFHPSLGPLERERL 1003 Query: 745 RGAKG-SLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQ--QFPGQPAM 801 A G +L P S + A+ + AA G +A + P++ Q + Sbjct: 1004 ALAAGPALRPDMSYAERLAAERQHAERVAALGNDPLARLQMLNVTPHHHQHSHIHSHLHL 1063 Query: 802 MQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSY 861 Q A + + P++ L SGSH I YP+ P P + Sbjct: 1064 HQQDAIHAASASVHPLIDP----LASGSHLTRI------PYPAGTLPNPLL-------PH 1106 Query: 862 PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQ 911 P H ++ HQ A P P S +AP HQ QA H S + Q+ Sbjct: 1107 PLHENEVLRHQLFAA--PYRDLPASL-SAPMSAAHQL-QAMHAQSAELQR 1152 Score = 40.4 bits (93), Expect = 0.009 Identities = 68/298 (22%), Positives = 92/298 (30%), Gaps = 41/298 (13%) Query: 385 HHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRM 444 HH ++ P PG+ + GG S + P + +L S P G +PPP Sbjct: 503 HHGNSGPPPPGAFPHPLEGGSSHHA----HPYAMSPSLGSLRPYPPGPAHLPPP------ 552 Query: 445 YPPRSPKSAAP--APISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLA 502 + S A P P+S+S S+ TS S P + G P + Sbjct: 553 HSQVSYSQAGPNGPPVSSSS-----NSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTV 607 Query: 503 PTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN 562 T LST T+ PG KR K +P S Sbjct: 608 TTSSATLSTVIA--TVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS---- 661 Query: 563 SLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPE 622 PP P G TS P G PP PSG P Sbjct: 662 -----PPSFRTGTPPGYRG------TSPPAGPGTFKPGSPTVGPGPLPPAGPSGL---PS 707 Query: 623 QPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTS 680 PPPP +G P + + P E + P A+ +P ++ V S Sbjct: 708 LPPPPAAPASGPP----LSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHAS 761 Score = 37.0 bits (84), Expect = 0.099 Identities = 31/95 (32%), Positives = 37/95 (38%), Gaps = 18/95 (18%) Query: 12 QPQQPPPTQQAVARRPPG--GTSPPNGGL----------PGPL---ATSAAPPGPPAAAS 56 +P PP + PPG GTSPP G PGPL S P PP A+ Sbjct: 658 KPGSPPSFRTGT---PPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAA 714 Query: 57 PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERP 91 P GP +A + AE P+ P P P Sbjct: 715 PASGPPLSATQIKQEPAEEYETPESPVPPARSPSP 749 Score = 35.8 bits (81), Expect = 0.22 Identities = 22/52 (42%), Positives = 25/52 (48%), Gaps = 6/52 (11%) Query: 4 PQPLQQ--PSQPQQ-PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPP 52 P P Q PS P PPPT +V+ +PP T P LP S PP PP Sbjct: 398 PFPASQALPSYPHSFPPPTSLSVSNQPPKYTQP---SLPSQAVWSQGPPPPP 446 Score = 35.8 bits (81), Expect = 0.22 Identities = 32/104 (30%), Positives = 37/104 (35%), Gaps = 19/104 (18%) Query: 8 QQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGS 67 QQ Q QQ QQ + PP G P PL ++ P A SP LG Sbjct: 485 QQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGS------ 538 Query: 68 GLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111 L P PP P H P + S G + GPP S Sbjct: 539 ---------LRPYPPGP-AHLPPPHSQVSYSQAGPN---GPPVS 569 Score = 33.9 bits (76), Expect = 0.84 Identities = 34/113 (30%), Positives = 42/113 (37%), Gaps = 16/113 (14%) Query: 4 PQPLQQPS-QPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPV 62 P PL PS QP P Q + P +P P TS PP A P P Sbjct: 161 PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPP--HPQ 218 Query: 63 AAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK--GPPQSPV 113 G G G+L+ P P+ G A S G + GK PP +P+ Sbjct: 219 LYPG-----GTGGVLSGPPMGPK------GGGAASSVGGPNGGKQHPPPTTPI 260 Score = 33.1 bits (74), Expect = 1.4 Identities = 28/96 (29%), Positives = 31/96 (32%), Gaps = 3/96 (3%) Query: 14 QQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGA 73 Q PPPT +PP P+ P PP A P + P LR Sbjct: 252 QHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLN 311 Query: 74 EGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109 A PP Q PG A GQ G PP Sbjct: 312 N---ASASPPGLGAQPLPGHLPSPHAMGQGMGGLPP 344 >gi|55750041 atrophin-1 [Homo sapiens] Length = 1190 Score = 78.2 bits (191), Expect = 4e-14 Identities = 147/626 (23%), Positives = 209/626 (33%), Gaps = 116/626 (18%) Query: 490 GSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEEL---R 546 G SP +S + +D K +++ + +E + G E + EE + Sbjct: 31 GRASPGG--VSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPK 88 Query: 547 KFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD--GLLTSEPMGSPVSSKTESVS 604 K + +L SP + LD R L ++ +++D TS + SP S + +S S Sbjct: 89 KTKTEQELPRPQSPSD-LDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDS 147 Query: 605 DKEDKPPLAPSGGTEGPEQP--PPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPN 662 SG ++GP +P PPP + PP + P A ++ P Sbjct: 148 S---------SGLSQGPARPYHPPPLFPPSPQPP------DSTPRQPEASFEPHPSVTPT 192 Query: 663 AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722 P + ++ P P+ + + VL+ G S + + G Sbjct: 193 GYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQ 252 Query: 723 VQAPQMYPYPVSNSVPGQQGKYR----------GAKGSLPPQRSDQHQPASAPPMMQAA- 771 P P+S S G G G S PP + H + PP Sbjct: 253 HPPPTT---PISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRP 309 Query: 772 ---AAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRML--- 825 A+A PP + A P P P AM Q M P P P L +P L Sbjct: 310 LNNASASPPGLGAQPL-------PGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPA 362 Query: 826 -------------TSGSHPQAIVSSSTPQYPSAEQPTP--QALYATVHQSYPHHATQLHA 870 +S S A SSS+ S+ P P QAL SYPH Sbjct: 363 SSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQAL-----PSYPHSF----- 412 Query: 871 HQPQPATTPTGSQPQ--SQHAAPSPVQHQAGQAPHLGSGQPQQNLY-HPGALTGTPPSLP 927 P P + +QP +Q + PS G P G+ N HPG Sbjct: 413 --PPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPG---------- 460 Query: 928 PGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQ 987 P P + QS+ P + + HHQQ Q Q + PPP PHP + Sbjct: 461 PFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLE 520 Query: 988 VMLLH------------------PPQSHGGPPQGAVPQS-----GVPALSASTPSPYPYI 1024 H P +H PP V S G P S+S S Sbjct: 521 GGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQ 580 Query: 1025 GHPQGEQPGQAPGFPGGADDRIPPLP 1050 G P + G P GA PP+P Sbjct: 581 GSYPCSHPSPSQG-PQGAPYPFPPVP 605 Score = 70.9 bits (172), Expect = 6e-12 Identities = 165/706 (23%), Positives = 230/706 (32%), Gaps = 108/706 (15%) Query: 391 SPGPGSEARGIN----GGPSRMSP--KAQRPLRGAKTL-----SSPSNRPSGETSVPPPP 439 +PGP E R GG S S KA++ + AK S+P G + Sbjct: 20 APGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISES 79 Query: 440 AVGRMYPPRSPKSAA--PAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPA-- 495 P+ K+ P P S S + G ++ +S P D S SP+ Sbjct: 80 ESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDI---DQDNRSTSPSIY 136 Query: 496 SPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQ 555 SP +D ++ P R P L + + P Q E Sbjct: 137 SPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHA 196 Query: 556 PSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSD----KEDKPP 611 P P + + PP P+ G+L+ PMG SV K+ PP Sbjct: 197 PMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPP 256 Query: 612 LAP-SGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTK 670 P S + G PP P T PVG G + P T N P Sbjct: 257 TTPISVSSSGASGAPPTKPPTT---PVG---GGNLPSAPPPANFPHVTPN-----LPPPP 305 Query: 671 PLLSVNKSTSTPTSPG--PRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQ-APQ 727 L +N ++++P G P PS + G GL P GP + +P Sbjct: 306 ALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLP--------PGPEKGPTLAPSPH 357 Query: 728 MYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSY 787 P P S+S P PP R +S+ +++++ + P S Sbjct: 358 SLP-PASSSAPA------------PPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQA 404 Query: 788 IPYNPQQFPGQPAM----MQPMAHYPSQPVFAPMLQSNP------RMLT-SGSHPQAIVS 836 +P P FP ++ P PS P A Q P R+L S +HP Sbjct: 405 LPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPP 464 Query: 837 SSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQ- 895 S+ Q S P P + + HQ Q Q Q S P A P P++ Sbjct: 465 STGAQ--STAHP-PVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEG 521 Query: 896 ------HQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQ--PAAVYA 947 H +P LGS +P Y PG P LPP S S + P P + + Sbjct: 522 GSSHHAHPYAMSPSLGSLRP----YPPG-----PAHLPPPHSQVSYSQAGPNGPPVSSSS 572 Query: 948 IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQ 1007 G +H + + G AP P P P + Sbjct: 573 NSSSSTSQGSYPCSHPSPSQ---GPQGAPYPFPPVPTVTT---------------SSATL 614 Query: 1008 SGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRIPPLPPPG 1053 S V A AS+P+ Y P G+ PG PP PG Sbjct: 615 STVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPG 660 Score = 65.1 bits (157), Expect = 3e-10 Identities = 146/633 (23%), Positives = 197/633 (31%), Gaps = 114/633 (18%) Query: 371 GGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS 430 GG G+ S PP GP G S G NGG P + + +P +P Sbjct: 222 GGTGGVLSGPPMGP-----KGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKP- 275 Query: 431 GETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVG 490 P VG P +P A ++ + P PP + +SAS P + PG Sbjct: 276 ------PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPG-- 327 Query: 491 SISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGA 550 P+ + + K P P L + P RF A Sbjct: 328 -HLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPA---PPMRFPYSSSSSSSA 383 Query: 551 QFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKP 610 SSS +S PFP L S P P P Sbjct: 384 AAS-SSSSSSSSSASPFP--------------ASQALPSYPHSFP--------------P 414 Query: 611 PLAPSGGTEGPEQPPPPCPSQT----GSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEF 666 P + S + P+ P PSQ G PP P + S +P Sbjct: 415 PTSLSVSNQPPKYTQPSLPSQAVWSQGPPP----------PPPYGRLLANSNAHP----- 459 Query: 667 NPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAP 726 P P + P S H Q Q Q H P Sbjct: 460 GPFPPSTGAQSTAHPPVSTHHHHHQQQQ-------QQQQQQQQQQQQQQQHHGNSGPPPP 512 Query: 727 QMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPP-----MMQAAAAAGPPLVAA 781 +P+P+ Y SL R PA PP A GPP+ ++ Sbjct: 513 GAFPHPLEGGSSHHAHPY-AMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSS 571 Query: 782 TPYSSYIPYN--PQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSST 839 + SS P P P+ A YP PV P + ++ L S A V+SS Sbjct: 572 SNSSSSTSQGSYPCSHP-SPSQGPQGAPYPFPPV--PTVTTSSATL---STVIATVASSP 625 Query: 840 PQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAG 899 Y +A P P P + + + TP G +P SP + G Sbjct: 626 AGYKTASPPGP-----------PPYGKRAPSPGAYKTATPPGYKP------GSPPSFRTG 668 Query: 900 QAP-HLGSGQPQ-QNLYHPGALTGTPPSLPP-GPSAQSPQSSFPQPAAVYAIHHQQLPHG 956 P + G+ P + PG+ T P LPP GPS S P P A A P Sbjct: 669 TPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSG---LPSLPPPPAAPA---SGPPLS 722 Query: 957 FTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVM 989 T + +T + PP +P PP+V+ Sbjct: 723 ATQIKQEPAEEYETPESPVPPARSPSP-PPKVV 754 Score = 60.1 bits (144), Expect = 1e-08 Identities = 131/564 (23%), Positives = 178/564 (31%), Gaps = 123/564 (21%) Query: 359 GPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNS----SPGPGSEARGINGG---------- 404 GP+GG SS G G PP P + +S +P + GG Sbjct: 234 GPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPAN 293 Query: 405 -----PSRMSPKAQRPLRGAKT-------------LSSPSNRPSGETSVPPPPAVGRMYP 446 P+ P A RPL A L SP G +PP P G Sbjct: 294 FPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLA 353 Query: 447 PRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDV 506 P SP S PA S+S P PP+ P +SS S S S +S S +P Sbjct: 354 P-SPHSLPPA--SSSAPAPPM---------RFPYSSSSSSSAAASSSSSSSSSSASPFPA 401 Query: 507 KELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSL-- 564 + P P L+ + N+ ++ L + P P L Sbjct: 402 SQALPSYPHSFPPPTSLS--------VSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLA 453 Query: 565 ------DPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSS-----KTESVSDKEDKPPLA 613 PFPP T+ P PVS+ + + ++ + Sbjct: 454 NSNAHPGPFPP------------STGAQSTAHP---PVSTHHHHHQQQQQQQQQQQQQQQ 498 Query: 614 PSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLL 673 G PPPP G+ P L G P A +L P P P Sbjct: 499 QQQQHHGNSGPPPP-----GAFPHPLEGGSSHHAHPYAMSPSLGSLRP-----YPPGP-- 546 Query: 674 SVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP- 732 P S + + P+ P +++ + S SY P H P+ Q PQ PYP Sbjct: 547 ---AHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSY-PCSHPSPS-QGPQGAPYPF 601 Query: 733 ------------VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAG----- 775 +S + G K + PP + A +P + A G Sbjct: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS 661 Query: 776 -PPLVAATP---YSSYIPYNPQQF-PGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSH 830 P TP + P P F PG P + P P+ P P L P SG Sbjct: 662 PPSFRTGTPPGYRGTSPPAGPGTFKPGSPT-VGPGPLPPAGPSGLPSLPPPPAAPASGPP 720 Query: 831 PQAIVSSSTP--QYPSAEQPTPQA 852 A P +Y + E P P A Sbjct: 721 LSATQIKQEPAEEYETPESPVPPA 744 Score = 40.8 bits (94), Expect = 0.007 Identities = 133/590 (22%), Positives = 201/590 (34%), Gaps = 102/590 (17%) Query: 351 PLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSP 410 P P R G + ++ G +PG P +P PG GP P Sbjct: 636 PPPYGKRAPSPGAYKTATPPGYKPG-------SPPSFRTGTP-PGYRGTSPPAGPGTFKP 687 Query: 411 KAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKS------------AAPAPI 458 + P G L P PSG S+PPPPA PP S +P P Sbjct: 688 GS--PTVGPGPL--PPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPP 743 Query: 459 SASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRT- 517 + S PP VP+ ++ + D G S A + P + +L+ K Sbjct: 744 ARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSC--ARSDLYFVPLEGSKLAKKRADLVE 801 Query: 518 ---LEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKL-QPSSSPEN--SLDPFPPRI 571 E ++ AR + + +K + E+ R+ KL Q +P SL P P R Sbjct: 802 KVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRP 861 Query: 572 LKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPC--P 629 E + T P P + ++S+ +P + G P P P Sbjct: 862 PFEPG-------SAVATVPPYLGPDTPALRTLSEYA-RPHVMSPGNRNHPFYVPLGAVDP 913 Query: 630 SQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTS--PGP 687 G L + P A + ++ + ++ KP V S P PGP Sbjct: 914 GLLGYNVPALYSSD-----PAAREREREARERDLRD--RLKPGFEVKPSELEPLHGVPGP 966 Query: 688 RTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQ--APQMYPYPVSNSV-PGQQGKY 744 P H G A+Q P ++P+P S+ P ++ + Sbjct: 967 GLDPFPR-----------------------HGGLALQPGPPGLHPFPFHPSLGPLERERL 1003 Query: 745 RGAKG-SLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQ--QFPGQPAM 801 A G +L P S + A+ + AA G +A + P++ Q + Sbjct: 1004 ALAAGPALRPDMSYAERLAAERQHAERVAALGNDPLARLQMLNVTPHHHQHSHIHSHLHL 1063 Query: 802 MQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSY 861 Q A + + P++ L SGSH I YP+ P P + Sbjct: 1064 HQQDAIHAASASVHPLIDP----LASGSHLTRI------PYPAGTLPNPLL-------PH 1106 Query: 862 PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQ 911 P H ++ HQ A P P S +AP HQ QA H S + Q+ Sbjct: 1107 PLHENEVLRHQLFAA--PYRDLPASL-SAPMSAAHQL-QAMHAQSAELQR 1152 Score = 40.4 bits (93), Expect = 0.009 Identities = 68/298 (22%), Positives = 92/298 (30%), Gaps = 41/298 (13%) Query: 385 HHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRM 444 HH ++ P PG+ + GG S + P + +L S P G +PPP Sbjct: 503 HHGNSGPPPPGAFPHPLEGGSSHHA----HPYAMSPSLGSLRPYPPGPAHLPPP------ 552 Query: 445 YPPRSPKSAAP--APISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLA 502 + S A P P+S+S S+ TS S P + G P + Sbjct: 553 HSQVSYSQAGPNGPPVSSSS-----NSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTV 607 Query: 503 PTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN 562 T LST T+ PG KR K +P S Sbjct: 608 TTSSATLSTVIA--TVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS---- 661 Query: 563 SLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPE 622 PP P G TS P G PP PSG P Sbjct: 662 -----PPSFRTGTPPGYRG------TSPPAGPGTFKPGSPTVGPGPLPPAGPSGL---PS 707 Query: 623 QPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTS 680 PPPP +G P + + P E + P A+ +P ++ V S Sbjct: 708 LPPPPAAPASGPP----LSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHAS 761 Score = 37.0 bits (84), Expect = 0.099 Identities = 31/95 (32%), Positives = 37/95 (38%), Gaps = 18/95 (18%) Query: 12 QPQQPPPTQQAVARRPPG--GTSPPNGGL----------PGPL---ATSAAPPGPPAAAS 56 +P PP + PPG GTSPP G PGPL S P PP A+ Sbjct: 658 KPGSPPSFRTGT---PPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAA 714 Query: 57 PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERP 91 P GP +A + AE P+ P P P Sbjct: 715 PASGPPLSATQIKQEPAEEYETPESPVPPARSPSP 749 Score = 35.8 bits (81), Expect = 0.22 Identities = 22/52 (42%), Positives = 25/52 (48%), Gaps = 6/52 (11%) Query: 4 PQPLQQ--PSQPQQ-PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPP 52 P P Q PS P PPPT +V+ +PP T P LP S PP PP Sbjct: 398 PFPASQALPSYPHSFPPPTSLSVSNQPPKYTQP---SLPSQAVWSQGPPPPP 446 Score = 35.8 bits (81), Expect = 0.22 Identities = 32/104 (30%), Positives = 37/104 (35%), Gaps = 19/104 (18%) Query: 8 QQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGS 67 QQ Q QQ QQ + PP G P PL ++ P A SP LG Sbjct: 485 QQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGS------ 538 Query: 68 GLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111 L P PP P H P + S G + GPP S Sbjct: 539 ---------LRPYPPGP-AHLPPPHSQVSYSQAGPN---GPPVS 569 Score = 33.9 bits (76), Expect = 0.84 Identities = 34/113 (30%), Positives = 42/113 (37%), Gaps = 16/113 (14%) Query: 4 PQPLQQPS-QPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPV 62 P PL PS QP P Q + P +P P TS PP A P P Sbjct: 161 PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPP--HPQ 218 Query: 63 AAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK--GPPQSPV 113 G G G+L+ P P+ G A S G + GK PP +P+ Sbjct: 219 LYPG-----GTGGVLSGPPMGPK------GGGAASSVGGPNGGKQHPPPTTPI 260 Score = 33.1 bits (74), Expect = 1.4 Identities = 28/96 (29%), Positives = 31/96 (32%), Gaps = 3/96 (3%) Query: 14 QQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGA 73 Q PPPT +PP P+ P PP A P + P LR Sbjct: 252 QHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLN 311 Query: 74 EGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109 A PP Q PG A GQ G PP Sbjct: 312 N---ASASPPGLGAQPLPGHLPSPHAMGQGMGGLPP 344 >gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo sapiens] Length = 1858 Score = 74.3 bits (181), Expect = 6e-13 Identities = 114/445 (25%), Positives = 154/445 (34%), Gaps = 67/445 (15%) Query: 651 AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQY 710 +EQ+ + + K P P L +STP +P + +P P G Y P + Sbjct: 1425 SEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSP--YRPHH 1482 Query: 711 ISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQA 770 S PQ+ G + PQ YP + ++P + G+L Q A+ Q Sbjct: 1483 -SQSPQV--GTPQREPQRNFYPAAQNLPANT--QQATSGTLFTQTPSGQSSATYSQFNQQ 1537 Query: 771 A--AAAGPPLVAATPYSSYIP----------YNP----------------QQFPGQPAMM 802 + + A PP P SSY YN Q PG + Sbjct: 1538 SLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQ 1597 Query: 803 QPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYP 862 H+ + F P NP + H Q + P P P P + S+ Sbjct: 1598 TVPGHHVTPGHFLP--SQNPTI-----HHQTAAAVVPPPPPPPPAPGPHLVQQP--NSHQ 1648 Query: 863 HHATQLHAHQPQPATTPTGSQPQSQHAA---------PSPVQHQAGQAPHLGSGQPQQNL 913 H+ H P A TP GS SQ A P P H PH +G Sbjct: 1649 QHSVA-HVVGPVHAVTP-GSHIHSQTAGHHLPPPPPPPGPAPHHH-PPPHPSTGLQGLQA 1705 Query: 914 YHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHH--QQLPHGFTNMAHVTQAHVQTG 971 H + PP PP P S +S + A+HH Q P F + AH T + Sbjct: 1706 QHQHVVNSAPPP-PPPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQ 1764 Query: 972 ITAAPPPHPGAPHPPQVMLLHPPQSHGGP---PQGAVPQSGVPALSASTPSPYP-YIGHP 1027 T PG H P H P GP PQG + +P +AS P+P + P Sbjct: 1765 ATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQG---PNSIPTPTASGFCPHPGSVALP 1821 Query: 1028 QGEQ-PGQAPGFPGGADDRIPPLPP 1051 G Q P QA PG +PP Sbjct: 1822 HGVQGPQQASPVPGQIPIHRAQVPP 1846 Score = 60.1 bits (144), Expect = 1e-08 Identities = 136/590 (23%), Positives = 205/590 (34%), Gaps = 109/590 (18%) Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASC---PEPPIGSAVPTSSAS 477 T PS S T PP +M P SP S PA P+P S V S A Sbjct: 1335 TNECPSPDTSQNTCKSPP----KMSKPGSPGSVIPAQAHGKIFTKPDPQWDSTVSASEAE 1390 Query: 478 --IPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQN 535 + + + + + + + A K T V+ S+++ + L P L+N Sbjct: 1391 NGVHLKTELQQKQLSNNNQALSKNHPPQTHVRN-SSEQLSQKLPSVPTKLHCPPSPHLEN 1449 Query: 536 EQKRFQLEE------------LRKFGAQFKLQPSSSPENSLDPFPPR-----ILKEEPKG 578 K ++ G+ ++ S SP+ P+ + P Sbjct: 1450 PPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPAN 1509 Query: 579 KEKEVDG-LLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQT---GS 634 ++ G L T P G SS T S +++ S + P PPPP PS + Sbjct: 1510 TQQATSGTLFTQTPSGQ--SSATYSQFNQQ-------SLNSTAPPPPPPPPPSSSYYQNQ 1560 Query: 635 PPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPS 694 P + ++ +G +++Q T PN ++ +TS T PG H TP Sbjct: 1561 QPSANFQNYNQLKGSLSQQT-VFTSGPNQ----------ALPGTTSQQTVPG--HHVTPG 1607 Query: 695 IPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVS---NSVPGQQGKYRGAK--G 749 L + ++ + +P P P + P S +SV G Sbjct: 1608 -HFLPSQNPTIHHQTAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGS 1666 Query: 750 SLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYP 809 + Q + H P PP GP P+ P+ G A Q + + Sbjct: 1667 HIHSQTAGHHLPPPPPP-------PGP-----APHHHPPPHPSTGLQGLQAQHQHVVNSA 1714 Query: 810 SQPVFAPMLQSNPRMLTSGSHPQAIVS------SSTPQYPSAEQPT--PQALYATVHQSY 861 P P S +L SG H + + P +PS+ PT P AT H + Sbjct: 1715 PPPPPPPPPSS---VLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHHTTL 1771 Query: 862 ----PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPG 917 H + H P P T P QPQ ++ P+P +G PH GS Sbjct: 1772 GPGPQHQPSGTGPHCPLPVTGP-HLQPQGPNSIPTPT--ASGFCPHPGS----------- 1817 Query: 918 ALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAH 967 +LP G Q PQ + P P + IH Q+P F N H + H Sbjct: 1818 ------VALPHG--VQGPQQASPVPGQI-PIHRAQVPPTFQNNYHGSGWH 1858 Score = 40.0 bits (92), Expect = 0.012 Identities = 37/151 (24%), Positives = 54/151 (35%), Gaps = 17/151 (11%) Query: 340 PSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEAR 399 PS G + Q + P G S P + P + HH ++ GPG + + Sbjct: 1723 PSSVLASGHHTTSAQALHHPPHQGPPLFPS-SAHPTVPPYPSQATHH---TTLGPGPQHQ 1778 Query: 400 GINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPIS 459 PS P P+ G P +P G S+P P A G + P A P + Sbjct: 1779 -----PSGTGPHCPLPVTG------PHLQPQGPNSIPTPTASG--FCPHPGSVALPHGVQ 1825 Query: 460 ASCPEPPIGSAVPTSSASIPVTSSVSDPGVG 490 P+ +P A +P T + G G Sbjct: 1826 GPQQASPVPGQIPIHRAQVPPTFQNNYHGSG 1856 >gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo sapiens] Length = 1858 Score = 74.3 bits (181), Expect = 6e-13 Identities = 114/445 (25%), Positives = 154/445 (34%), Gaps = 67/445 (15%) Query: 651 AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQY 710 +EQ+ + + K P P L +STP +P + +P P G Y P + Sbjct: 1425 SEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSP--YRPHH 1482 Query: 711 ISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQA 770 S PQ+ G + PQ YP + ++P + G+L Q A+ Q Sbjct: 1483 -SQSPQV--GTPQREPQRNFYPAAQNLPANT--QQATSGTLFTQTPSGQSSATYSQFNQQ 1537 Query: 771 A--AAAGPPLVAATPYSSYIP----------YNP----------------QQFPGQPAMM 802 + + A PP P SSY YN Q PG + Sbjct: 1538 SLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQ 1597 Query: 803 QPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYP 862 H+ + F P NP + H Q + P P P P + S+ Sbjct: 1598 TVPGHHVTPGHFLP--SQNPTI-----HHQTAAAVVPPPPPPPPAPGPHLVQQP--NSHQ 1648 Query: 863 HHATQLHAHQPQPATTPTGSQPQSQHAA---------PSPVQHQAGQAPHLGSGQPQQNL 913 H+ H P A TP GS SQ A P P H PH +G Sbjct: 1649 QHSVA-HVVGPVHAVTP-GSHIHSQTAGHHLPPPPPPPGPAPHHH-PPPHPSTGLQGLQA 1705 Query: 914 YHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHH--QQLPHGFTNMAHVTQAHVQTG 971 H + PP PP P S +S + A+HH Q P F + AH T + Sbjct: 1706 QHQHVVNSAPPP-PPPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQ 1764 Query: 972 ITAAPPPHPGAPHPPQVMLLHPPQSHGGP---PQGAVPQSGVPALSASTPSPYP-YIGHP 1027 T PG H P H P GP PQG + +P +AS P+P + P Sbjct: 1765 ATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQG---PNSIPTPTASGFCPHPGSVALP 1821 Query: 1028 QGEQ-PGQAPGFPGGADDRIPPLPP 1051 G Q P QA PG +PP Sbjct: 1822 HGVQGPQQASPVPGQIPIHRAQVPP 1846 Score = 60.1 bits (144), Expect = 1e-08 Identities = 136/590 (23%), Positives = 205/590 (34%), Gaps = 109/590 (18%) Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASC---PEPPIGSAVPTSSAS 477 T PS S T PP +M P SP S PA P+P S V S A Sbjct: 1335 TNECPSPDTSQNTCKSPP----KMSKPGSPGSVIPAQAHGKIFTKPDPQWDSTVSASEAE 1390 Query: 478 --IPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQN 535 + + + + + + + A K T V+ S+++ + L P L+N Sbjct: 1391 NGVHLKTELQQKQLSNNNQALSKNHPPQTHVRN-SSEQLSQKLPSVPTKLHCPPSPHLEN 1449 Query: 536 EQKRFQLEE------------LRKFGAQFKLQPSSSPENSLDPFPPR-----ILKEEPKG 578 K ++ G+ ++ S SP+ P+ + P Sbjct: 1450 PPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPAN 1509 Query: 579 KEKEVDG-LLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQT---GS 634 ++ G L T P G SS T S +++ S + P PPPP PS + Sbjct: 1510 TQQATSGTLFTQTPSGQ--SSATYSQFNQQ-------SLNSTAPPPPPPPPPSSSYYQNQ 1560 Query: 635 PPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPS 694 P + ++ +G +++Q T PN ++ +TS T PG H TP Sbjct: 1561 QPSANFQNYNQLKGSLSQQT-VFTSGPNQ----------ALPGTTSQQTVPG--HHVTPG 1607 Query: 695 IPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVS---NSVPGQQGKYRGAK--G 749 L + ++ + +P P P + P S +SV G Sbjct: 1608 -HFLPSQNPTIHHQTAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGS 1666 Query: 750 SLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYP 809 + Q + H P PP GP P+ P+ G A Q + + Sbjct: 1667 HIHSQTAGHHLPPPPPP-------PGP-----APHHHPPPHPSTGLQGLQAQHQHVVNSA 1714 Query: 810 SQPVFAPMLQSNPRMLTSGSHPQAIVS------SSTPQYPSAEQPT--PQALYATVHQSY 861 P P S +L SG H + + P +PS+ PT P AT H + Sbjct: 1715 PPPPPPPPPSS---VLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHHTTL 1771 Query: 862 ----PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPG 917 H + H P P T P QPQ ++ P+P +G PH GS Sbjct: 1772 GPGPQHQPSGTGPHCPLPVTGP-HLQPQGPNSIPTPT--ASGFCPHPGS----------- 1817 Query: 918 ALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAH 967 +LP G Q PQ + P P + IH Q+P F N H + H Sbjct: 1818 ------VALPHG--VQGPQQASPVPGQI-PIHRAQVPPTFQNNYHGSGWH 1858 Score = 40.0 bits (92), Expect = 0.012 Identities = 37/151 (24%), Positives = 54/151 (35%), Gaps = 17/151 (11%) Query: 340 PSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEAR 399 PS G + Q + P G S P + P + HH ++ GPG + + Sbjct: 1723 PSSVLASGHHTTSAQALHHPPHQGPPLFPS-SAHPTVPPYPSQATHH---TTLGPGPQHQ 1778 Query: 400 GINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPIS 459 PS P P+ G P +P G S+P P A G + P A P + Sbjct: 1779 -----PSGTGPHCPLPVTG------PHLQPQGPNSIPTPTASG--FCPHPGSVALPHGVQ 1825 Query: 460 ASCPEPPIGSAVPTSSASIPVTSSVSDPGVG 490 P+ +P A +P T + G G Sbjct: 1826 GPQQASPVPGQIPIHRAQVPPTFQNNYHGSG 1856 >gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] Length = 1336 Score = 73.9 bits (180), Expect = 7e-13 Identities = 89/370 (24%), Positives = 120/370 (32%), Gaps = 51/370 (13%) Query: 720 GPAVQAPQMYPYP----------VSNSVPGQQGKYR--GAKGSLPPQRSDQHQPASAPP- 766 GP Q PQ + P PG QG++R G +G + PQ HQ P Sbjct: 592 GPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQG 651 Query: 767 MMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLT 826 M GPP P + P Q+ PG + P Q P P+ Sbjct: 652 FMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQ--- 708 Query: 827 SGSHPQAIVSSSTPQYPSAE--------------QPTPQALYATVHQSYPHHATQLHAHQ 872 PQ + P P P P+ + H Q Sbjct: 709 GPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQ 768 Query: 873 PQPATTPT-GSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNL---YHPGALTGTPPSLPP 928 + P G P+ P P ++Q + G P Q + + PG L G P Sbjct: 769 GPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMR 828 Query: 929 GPSA-QSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQ 987 GP + Q PQ + + + P G + Q + PPP G PP Sbjct: 829 GPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSL------GPPPQGGMQGPPG 882 Query: 988 VMLLHPPQSHGGPPQGAVP--QSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPG----G 1041 P P QG +P Q P L +P+ + +G+ G P PG G Sbjct: 883 PQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPF----NQEGQSTGPPPLIPGLGQQG 938 Query: 1042 ADDRIPPLPP 1051 A RIPPL P Sbjct: 939 AQGRIPPLNP 948 Score = 63.2 bits (152), Expect = 1e-09 Identities = 89/330 (26%), Positives = 104/330 (31%), Gaps = 45/330 (13%) Query: 758 QHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAP- 816 Q P+S P++ G ++ P P+ QQ P A M P Q F P Sbjct: 573 QPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPG---PQGQFRPP 629 Query: 817 -----MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAH 871 M P + G PQ + PQ P P PQ ++ Q H Sbjct: 630 GPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGP--QGMQRHPGPHGPL 687 Query: 872 QPQPATTPTGSQPQSQHAAPS----PVQHQAGQAP-----HLGSGQPQ--QNLYHPGALT 920 PQ P GS H P P H Q P HLG P Q + P Sbjct: 688 GPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPR 747 Query: 921 GT-----PPSLPPGPSAQSPQSSFPQ-PAAVYAIHHQQLPHGFTNMAHVTQAHVQTG-IT 973 G P + GP +Q Q Q P Q P G Q G I Sbjct: 748 GMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPG----PRENQGPAPQGMIM 803 Query: 974 AAPPPHPGAPHPPQVMLLHPPQSHGGPP-----QGAVPQS---GVPALSASTPSPYPYIG 1025 PP PHPP +L H PQ GP QG PQ G P P G Sbjct: 804 GHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQG 863 Query: 1026 HPQGE----QPGQAPGFPGGADDRIPPLPP 1051 PQG G G PG + P P Sbjct: 864 PPQGSLGPPPQGGMQGPPGPQGQQNPARGP 893 Score = 40.8 bits (94), Expect = 0.007 Identities = 79/342 (23%), Positives = 111/342 (32%), Gaps = 55/342 (16%) Query: 350 IPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMS 409 +P PQ + GP+G R G L P+GP PGP +G +G M Sbjct: 665 LPRPQDMH-GPQGMQRHPGPHG------PLGPQGP-------PGP----QGSSGPQGHMG 706 Query: 410 PKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAP------------ 457 P+ +G P P G PP M P P+ P Sbjct: 707 PQGPPGPQGHIGPQGPPG-PQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQ 765 Query: 458 -ISASCPEPPIGSAVPTSSASIPVTSSVSDPGV-GSISPASPKISLAPTDVKELSTKEPG 515 I + P+ P P P G I P+ P L P Sbjct: 766 GIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQ 825 Query: 516 RTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEE 575 PQE+ + G P +ELR G P+ SL P PP+ + Sbjct: 826 EMRGPQEIRGMQGPPP---QGSMLGPPQELR--GPPGSQSQQGPPQGSLGP-PPQGGMQG 879 Query: 576 PKGKEKEVDGLLTSEPMGSPV---SSKTESVSD-----------KEDKPPLAPSGGTEGP 621 P G + + + P P+ KT + D PPL P G +G Sbjct: 880 PPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGA 939 Query: 622 E-QPPPPCPSQTGSPPVGLIKGEDKDE-GPVAEQVKKSTLNP 661 + + PP P Q P G +G GP++E+ + + P Sbjct: 940 QGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGP 981 Score = 39.7 bits (91), Expect = 0.015 Identities = 57/199 (28%), Positives = 73/199 (36%), Gaps = 33/199 (16%) Query: 612 LAPSG--GTEGPEQPPPPCPSQTGSPPVGLIKGEDKD--EGPVAEQVKKSTLNPNAKEFN 667 L P G GT+G + PP P Q P G+ G +GPV+ Q LNP + Sbjct: 729 LGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVS-QGPLMGLNPRGMQ-G 786 Query: 668 PTKPLLSVNKSTSTPTSPG------PRTHSTPSIP--VLTAGQSGLYSPQYISYIPQIHM 719 P P + P G P+ P P +L G + PQ I + Sbjct: 787 PPGP-----RENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGM----Q 837 Query: 720 GPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSL--PPQRSDQHQPASAPPMMQAAAAAGPP 777 GP Q + P PG Q + +GSL PPQ Q P P Q A GP Sbjct: 838 GPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPG---PQGQQNPARGP- 893 Query: 778 LVAATPYSSYIPYNPQQFP 796 P IP+ Q+ P Sbjct: 894 ----HPSQGPIPFQQQKTP 908 Score = 38.9 bits (89), Expect = 0.026 Identities = 41/151 (27%), Positives = 51/151 (33%), Gaps = 44/151 (29%) Query: 2 LKPQPLQQPSQPQQPP-----------PTQQAVARRPPGGT------------------- 31 L P+ +Q P P++ P Q+ PPGG Sbjct: 779 LNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQG 838 Query: 32 SPPNGGLPGPLATSAAPPGPPAAASP---CLGPVAAAG-------SGLRRGAEGILAPQP 81 PP G + GP PPG + P LGP G G + A G Q Sbjct: 839 PPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQG 898 Query: 82 PPPQQHQERP----GAAAIGSARGQSTGKGP 108 P P Q Q+ P G A + GQSTG P Sbjct: 899 PIPFQQQKTPLLGDGPRAPFNQEGQSTGPPP 929 Score = 38.5 bits (88), Expect = 0.034 Identities = 48/195 (24%), Positives = 53/195 (27%), Gaps = 31/195 (15%) Query: 859 QSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGA 918 Q P T L QP P P PQ P P Q +G PQ PG Sbjct: 573 QPPPSSGTPLLGPQPFPGQGPMSQIPQG-FQQPHPSQQMPMNMAQMGPPGPQGQFRPPGP 631 Query: 919 LTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPP 978 P PP F P Q P G P Sbjct: 632 QGQMGPQGPPLHQGGGGPQGFMGP---------QGPQG---------------------P 661 Query: 979 HPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGF 1038 G P P + Q H GP PQ +S P + P G Q P Sbjct: 662 PQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQG 721 Query: 1039 PGGADDRIPPLPPPG 1053 P G + P PPG Sbjct: 722 PPGPQGHLGPQGPPG 736 Score = 38.5 bits (88), Expect = 0.034 Identities = 37/121 (30%), Positives = 41/121 (33%), Gaps = 21/121 (17%) Query: 1 MLKPQPL-------QQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPA 53 +L PQP Q P QQP P+QQ G P G PPGP Sbjct: 582 LLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQG--------QFRPPGPQG 633 Query: 54 AASPCLGPVAAAGSGLRRGAEGILAPQPPP-----PQQHQERPGAAAIGSARGQSTGKGP 108 P GP G G +G G PQ PP PQ G G +GP Sbjct: 634 QMGP-QGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGP 692 Query: 109 P 109 P Sbjct: 693 P 693 Score = 38.1 bits (87), Expect = 0.044 Identities = 39/128 (30%), Positives = 45/128 (35%), Gaps = 31/128 (24%) Query: 4 PQPLQQPSQPQQPPPT---------QQAVARRP-PGGTSPPNGGLPGPLATSA-----AP 48 PQ P PQ PP Q + R P P G P G PGP +S P Sbjct: 649 PQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGP-PGPQGSSGPQGHMGP 707 Query: 49 PGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGP 108 GPP GP G G +G L PQ PP Q + P G +GP Sbjct: 708 QGPP-------GPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGP--------PGPRGMQGP 752 Query: 109 PQSPVFEG 116 P +G Sbjct: 753 PHPHGIQG 760 Score = 37.4 bits (85), Expect = 0.076 Identities = 47/163 (28%), Positives = 55/163 (33%), Gaps = 21/163 (12%) Query: 908 QPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQ------PAAVYAIHHQQL-PHGFTNM 960 Q Q P +GTP P Q P S PQ P+ ++ Q+ P G Sbjct: 566 QKQVEQIQPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQ 625 Query: 961 AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGV--PALSASTP 1018 Q G PP H G P M PQ GPPQG + P P Sbjct: 626 FRPPGPQGQMG-PQGPPLHQGGGGPQGFM---GPQGPQGPPQGLPRPQDMHGPQGMQRHP 681 Query: 1019 SPYPYIG-----HPQGE---QPGQAPGFPGGADDRIPPLPPPG 1053 P+ +G PQG Q P P G I P PPG Sbjct: 682 GPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPG 724 Score = 34.3 bits (77), Expect = 0.64 Identities = 42/132 (31%), Positives = 49/132 (37%), Gaps = 30/132 (22%) Query: 4 PQPLQQPSQPQ-----QPPPTQQAVA-----RRPPGGTSPPNGGLPGPLATSAAP----- 48 PQ +P PQ Q PP Q P G PP G LP P Sbjct: 622 PQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQG-LPRPQDMHGPQGMQRH 680 Query: 49 PGPPAAASPCLGPVAAAGSGLRRGAEGILAPQ-PPPPQQH---QERPGAAAIGSARGQST 104 PGP P GP GS G +G + PQ PP PQ H Q PG +G Sbjct: 681 PGPHGPLGP-QGPPGPQGSS---GPQGHMGPQGPPGPQGHIGPQGPPG------PQGHLG 730 Query: 105 GKGPPQSPVFEG 116 +GPP + +G Sbjct: 731 PQGPPGTQGMQG 742 >gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo sapiens] Length = 1636 Score = 73.6 bits (179), Expect = 1e-12 Identities = 112/392 (28%), Positives = 139/392 (35%), Gaps = 68/392 (17%) Query: 683 TSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQG 742 T PGP S P P +G + L P+ P H P P +YP P G Sbjct: 780 TGPGPHYLSGPLPPGTYSGPTQLIQPR----APGPHAMPVAPGPALYPAPAYTPELG--- 832 Query: 743 KYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGP-PLVAATPYSSYIPYNPQQFPG-QPA 800 L P+ S QH S+P + GP P VA P + P QF G + A Sbjct: 833 --------LVPRSSPQHGVVSSPYV-----GVGPAPPVAGLPSAP-----PPQFSGPELA 874 Query: 801 MMQPMAHYPSQPVFAPM-LQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQ 859 M A + AP+ + PR + + P PQ PTP A Q Sbjct: 875 MAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQ----PLPTPYTYPAGAKQ 930 Query: 860 SYP---HHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHP 916 P H ++ + A P P P QPQ H P P Q Q P +L+ P Sbjct: 931 PIPAQHHFSSGIPAGFPAPRIGP---QPQP-HPQPHPSQAFGPQPPQQPLPLQHPHLFPP 986 Query: 917 GALTGTPPSLPPGPSAQSPQSSFPQPAAVYA----IHHQQLPHGFTNMAHVTQAHVQTGI 972 A P LPP QSP PQP + +H Q P Q + Sbjct: 987 QA----PGLLPP----QSPYPYAPQPGVLGQPPPPLHTQLYPGP-------AQDPLPAHS 1031 Query: 973 TAAPPPHPGA---PHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQG 1029 A P P PG PHPP P GP + G + STPSP+ Sbjct: 1032 GALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLV------ 1085 Query: 1030 EQPGQAPGFPGGADDRIPPLPPPGELKIVLAA 1061 P +PG PG R P PP L+ AA Sbjct: 1086 PSPAPSPG-PGPVPPRPPAAEPPPCLRRGAAA 1116 Score = 47.8 bits (112), Expect = 6e-05 Identities = 93/382 (24%), Positives = 119/382 (31%), Gaps = 74/382 (19%) Query: 610 PPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNP- 668 P PS GP P P T S P LI + + GP A V A + P Sbjct: 773 PSPFPSSTGPGPHYLSGPLPPGTYSGPTQLI--QPRAPGPHAMPVAPGPALYPAPAYTPE 830 Query: 669 ------TKPLLSVNKSTSTPTSPGPRTHSTPSIPV--------------LTAGQSGLYSP 708 + P V S P P PS P T + +P Sbjct: 831 LGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAP 890 Query: 709 QYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMM 768 P+ + PA P +P P +P GAK +P Q H +S P Sbjct: 891 IPSHTAPRPNPTPA-PPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQ----HHFSSGIPAG 945 Query: 769 QAAAAAGP---PLVAATPYSSYIPYNPQQ---------FPGQ-PAMMQPMAHYPSQPVFA 815 A GP P P ++ P PQQ FP Q P ++ P + YP P Sbjct: 946 FPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPG 1005 Query: 816 PMLQSNPRMLT--------------SGSHPQAIVSSSTPQYP--------SAEQPTPQAL 853 + Q P + T SG+ P P +P S PQA Sbjct: 1006 VLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAA 1065 Query: 854 YATVH------QSYPH-HATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGS 906 T+ QS P H A P P P P+ A P P + A L S Sbjct: 1066 PLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVP----PRPPAAEPPPCLRRGAAAADLLS 1121 Query: 907 GQPQQNLYHPGALTGTPPSLPP 928 P+ + G P L P Sbjct: 1122 SSPESQHGGTQSPGGGQPLLQP 1143 Score = 44.3 bits (103), Expect = 6e-04 Identities = 113/459 (24%), Positives = 150/459 (32%), Gaps = 118/459 (25%) Query: 374 PGLSSLPPRGPHHLDNSSP--------------GPGSEARGINGGPSRMSPKAQRPLRGA 419 P SS P GPH+L P PG A + GP+ A P G Sbjct: 775 PFPSSTGP-GPHYLSGPLPPGTYSGPTQLIQPRAPGPHAMPVAPGPALYPAPAYTPELGL 833 Query: 420 KTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE--PPIGSAVPTSSAS 477 SSP + V P VG PAP A P PP S + A Sbjct: 834 VPRSSPQH------GVVSSPYVG----------VGPAPPVAGLPSAPPPQFSGPELAMAV 877 Query: 478 IPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQ 537 P T++V S +P+ + P P + L K P Q Sbjct: 878 RPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQP--IPAQ 935 Query: 538 KRFQLE-----ELRKFGAQFKLQPSSSPENSLDPFPPR--ILKEEPKGKEKEVDGLLTSE 590 F + G Q + P P + P PP+ + + P + GLL Sbjct: 936 HHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLL--- 992 Query: 591 PMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPV 650 P SP P AP G G QPPPP +Q L G +D P Sbjct: 993 PPQSPY--------------PYAPQPGVLG--QPPPPLHTQ-------LYPGPAQDPLPA 1029 Query: 651 AEQVKKSTLNPNAKEFNPTKPLLSVNKSTST-PTSP--GPRTHSTPSIPVLTAGQSGLYS 707 P+ P P L+ + ST P P P T PS +AGQS Sbjct: 1030 HSGALPF---PSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPS----SAGQS---- 1078 Query: 708 PQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPM 767 +P + P P + P G +PP+ PA+ PP Sbjct: 1079 ---------------TPSPHLVPSPAPSPGP----------GPVPPR-----PPAAEPPP 1108 Query: 768 MQAAAAAGPPLVAATPYSSYIPYNPQQFP--GQPAMMQP 804 AA L++++P S + Q P GQP ++QP Sbjct: 1109 CLRRGAAAADLLSSSPESQ---HGGTQSPGGGQP-LLQP 1143 Score = 42.4 bits (98), Expect = 0.002 Identities = 30/86 (34%), Positives = 37/86 (43%), Gaps = 18/86 (20%) Query: 26 RPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQ 85 RPPGG P LPGP A PPG P A+ P P+ ++ + +P P PQ Sbjct: 1508 RPPGGLESPVASLPGP----AEPPGLPPASLPESTPIPSS------SPPPLSSPLPEAPQ 1557 Query: 86 QHQERPGAAAIGSARGQSTGKGPPQS 111 +E P A S GPP S Sbjct: 1558 PKEEPPVPEAPSS--------GPPSS 1575 Score = 38.1 bits (87), Expect = 0.044 Identities = 117/500 (23%), Positives = 163/500 (32%), Gaps = 91/500 (18%) Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464 P +PK P R + P S+PP G PR P+ Sbjct: 718 PRPTAPKPLLPRREESEAVEAGDPPEELRSLPPDMVAG----PR-------------LPD 760 Query: 465 PPIGSAVPTSSASIPVTSSVSDPGVGSIS-PASPKISLAPTDVKELSTKEPGRTLEPQEL 523 +GSA P P SS + PG +S P P PT + + + PG P Sbjct: 761 TFLGSATPLHFPPSPFPSS-TGPGPHYLSGPLPPGTYSGPTQL--IQPRAPGPHAMP--- 814 Query: 524 ARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEV 583 PG L + + L P SSP++ + P G V Sbjct: 815 -----VAPGP-------ALYPAPAYTPELGLVPRSSPQHGVVSSP-----YVGVGPAPPV 857 Query: 584 DGLLTSEP-------MGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPC----PSQT 632 GL ++ P + V T +V + P + PPPPC P Q Sbjct: 858 AGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQP 917 Query: 633 GSPPVGLIKGEDKDEGPVAEQVKKSTLNP---NAKEFNP-----TKPLLSVNKSTSTPTS 684 P G + P+ Q S+ P A P +P S P Sbjct: 918 LPTPYTYPAGAKQ---PIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQ 974 Query: 685 PGPRTHSTPSIPVLTAGQS-GLYSPQY-ISYIPQ---IHMGPAVQAPQMYPYPVSNSVPG 739 P P H P L Q+ GL PQ Y PQ + P Q+YP P + +P Sbjct: 975 PLPLQH-----PHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPA 1029 Query: 740 QQG--KYRGAKGSLPPQRSDQHQPA-SAPPMMQAAA---AAGPPLVAATPYSSYIPYNPQ 793 G + PP + PA S PM AA GP + S ++ +P Sbjct: 1030 HSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPA 1089 Query: 794 QFPG------QPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHP----QAIVSSSTPQYP 843 PG +P +P A +L S+P G+ Q ++ + + Sbjct: 1090 PSPGPGPVPPRPPAAEPPPCLRRGAAAADLLSSSPESQHGGTQSPGGGQPLLQPT--KVD 1147 Query: 844 SAEQPTPQALYATVHQSYPH 863 +AE PQAL Y H Sbjct: 1148 AAEGRRPQALRLIERDPYEH 1167 Score = 36.2 bits (82), Expect = 0.17 Identities = 38/132 (28%), Positives = 43/132 (32%), Gaps = 28/132 (21%) Query: 4 PQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGG-----LPGPLATSAAPPGPPAAASPC 58 P P P+ +QP P Q + P G P G P P + A P PP P Sbjct: 919 PTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPL 978 Query: 59 LGPVAAAGSGLRRGAEGILAP--------------QPPPPQQHQERPGAA----AIGSAR 100 P A G+L P QPPPP Q PG A S Sbjct: 979 QHPHLFPPQ-----APGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGA 1033 Query: 101 GQSTGKGPPQSP 112 GPPQ P Sbjct: 1034 LPFPSPGPPQPP 1045 Score = 36.2 bits (82), Expect = 0.17 Identities = 38/121 (31%), Positives = 44/121 (36%), Gaps = 19/121 (15%) Query: 3 KPQPLQQPSQ------PQQPPPTQ-------QAVARRPPGGTSP-PNGGLPGPLATSAAP 48 +P P PSQ PQQP P Q QA PP SP P PG L P Sbjct: 956 QPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPP--QSPYPYAPQPGVLGQPPPP 1013 Query: 49 PGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPP-PPQQHQERPGAAAIGSARGQSTGKG 107 P P+ A L + G PQPP PP + P +G T +G Sbjct: 1014 LHTQLYPGPAQDPLPAHSGALPFPSPG--PPQPPHPPLAYGPAPSTRPMGPQAAPLTIRG 1071 Query: 108 P 108 P Sbjct: 1072 P 1072 Score = 35.8 bits (81), Expect = 0.22 Identities = 51/201 (25%), Positives = 73/201 (36%), Gaps = 29/201 (14%) Query: 351 PLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSP 410 PL ++ GP + S G P S PP+ PH P P + G P + Sbjct: 1013 PLHTQLYPGPAQDPLPAHS-GALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTI-- 1069 Query: 411 KAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSA 470 + P ++ SP PS S P P PPR P + EPP Sbjct: 1070 --RGPSSAGQSTPSPHLVPSPAPSPGPGPV-----PPRPPAA-----------EPPPCLR 1111 Query: 471 VPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKV 530 ++A + +S S G G+ SP + L PT V + P + R+ + Sbjct: 1112 RGAAAADLLSSSPESQHG-GTQSPGGGQPLLQPTKVDAAEGRRP-------QALRLIERD 1163 Query: 531 PGLQNEQKRFQLEELRKFGAQ 551 P E+ R +EL F Q Sbjct: 1164 PYEHPERLRQLQQELEAFRGQ 1184 Score = 32.3 bits (72), Expect = 2.4 Identities = 28/94 (29%), Positives = 30/94 (31%), Gaps = 10/94 (10%) Query: 4 PQPLQQPSQPQQPPPTQ-QAVARRPPG---------GTSPPNGGLPGPLATSAAPPGPPA 53 P P P QP PP A + RP G G S P P + P P Sbjct: 1035 PFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGP 1094 Query: 54 AASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQH 87 P P A LRRGA P QH Sbjct: 1095 GPVPPRPPAAEPPPCLRRGAAAADLLSSSPESQH 1128 Score = 32.0 bits (71), Expect = 3.2 Identities = 37/148 (25%), Positives = 57/148 (38%), Gaps = 21/148 (14%) Query: 421 TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAP--APISASCPEPPIGSAVPTSSASI 478 T++ S RP G P G PP P ++ P PI +S P PP+ S +P + Sbjct: 1501 TIAKLSIRPPGGLESPVASLPGPAEPPGLPPASLPESTPIPSSSP-PPLSSPLPEAPQ-- 1557 Query: 479 PVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQK 538 P + AP+ S+ E +L P+ + + + G Q K Sbjct: 1558 --------------PKEEPPVPEAPSSGPPSSSLELLASLTPEAFS-LDSSLRGKQRMSK 1602 Query: 539 RFQLEELRKFGAQFKLQPSSSPENSLDP 566 L+ G + +PS P + LDP Sbjct: 1603 HNFLQAHNGQGLR-ATRPSDDPLSLLDP 1629 Score = 32.0 bits (71), Expect = 3.2 Identities = 30/110 (27%), Positives = 42/110 (38%), Gaps = 25/110 (22%) Query: 927 PPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPP 986 PPG +SP +S P PA + LP T I ++ PP +P P Sbjct: 1509 PPG-GLESPVASLPGPAEPPGLPPASLPES-------------TPIPSSSPPPLSSPLP- 1553 Query: 987 QVMLLHPPQSHGGPPQGAVPQSGVPA-----LSASTPSPYPYIGHPQGEQ 1031 PQ PP P SG P+ L++ TP + +G+Q Sbjct: 1554 -----EAPQPKEEPPVPEAPSSGPPSSSLELLASLTPEAFSLDSSLRGKQ 1598 Score = 31.2 bits (69), Expect = 5.4 Identities = 26/84 (30%), Positives = 34/84 (40%), Gaps = 4/84 (4%) Query: 560 PENSLDPFPPRILKEEPKGKEKEVDGLL-TSEPMGSPVSSKTESVSDKEDKPPLAPSGGT 618 P +S+ ++ P G E V L +EP G P +S ES PP S Sbjct: 1494 PISSIQATIAKLSIRPPGGLESPVASLPGPAEPPGLPPASLPESTPIPSSSPPPLSSPLP 1553 Query: 619 EGP---EQPPPPCPSQTGSPPVGL 639 E P E+PP P +G P L Sbjct: 1554 EAPQPKEEPPVPEAPSSGPPSSSL 1577 Score = 30.8 bits (68), Expect = 7.1 Identities = 30/111 (27%), Positives = 36/111 (32%), Gaps = 5/111 (4%) Query: 7 LQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAG 66 +Q P P A PP PP LP P A P A + A Sbjct: 887 IQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGF 946 Query: 67 SGLRRGAEGILAPQPPPPQQHQERPGAAAIGSAR-----GQSTGKGPPQSP 112 R G + PQP P Q +P + Q+ G PPQSP Sbjct: 947 PAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSP 997 >gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] Length = 2217 Score = 73.2 bits (178), Expect = 1e-12 Identities = 113/438 (25%), Positives = 150/438 (34%), Gaps = 55/438 (12%) Query: 621 PEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTS 680 P PPP P TG G+ G + + T P P PL V Sbjct: 708 PVLPPPSTPMPTGP-------GQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPV----- 755 Query: 681 TPTSPGPRTHSTPSIPVLTAGQSGLYSPQYIS--YIPQIHMGPAVQAP-QMYPYPVSNSV 737 P +P A S + +P + +PQ + P Q P QM P PV + Sbjct: 756 -----------PPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPI 804 Query: 738 PGQQGKYRGAKGSLPPQRSDQHQ---PASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQ 794 G LPP D P PP + A P L A P +S P P Q Sbjct: 805 TPLAGI-----DGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPAS--PALPLQ 857 Query: 795 F------PGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVS-SSTPQYPSAEQ 847 PG P M P+ P P+L P + + S A+ P YP+A Sbjct: 858 AVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAA-- 915 Query: 848 PTPQALYATVHQSYPHHATQ-LHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGS 906 PQ V S PHH Q + A PQPA P + P P P P + Sbjct: 916 -FPQMAPTDVPPS-PHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPT 973 Query: 907 GQPQQNLYHPGALTGTPPSLPPGPS----AQSPQSSFPQPAAVYAIHHQQLPHGFTNMAH 962 +P Q + P + P LPP P+ + Q P+ AA A Q+ G + Sbjct: 974 -RPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHP-APY 1031 Query: 963 VTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQG-AVPQSGVPALSASTPSPY 1021 Q PP +P P+V+L P+ P A + V ++ T + Sbjct: 1032 AVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLL 1091 Query: 1022 PYIGHPQGEQPGQAPGFP 1039 P P PG A P Sbjct: 1092 PPANPPLPGGPGIASPCP 1109 Score = 48.9 bits (115), Expect = 3e-05 Identities = 66/233 (28%), Positives = 81/233 (34%), Gaps = 44/233 (18%) Query: 840 PQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQH--------AAP 891 P+ P A+Q L T+ S A+ Q +T + SQ Q AAP Sbjct: 589 PEEPEADQ---HLLPPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAP 645 Query: 892 SPVQ----HQAGQAPHLGSGQPQQNLYH-PGALTGTPPSLPPGPSAQ-SPQSSFPQPAAV 945 SP Q + P L P Y P A G P P P+ S Q FP PA Sbjct: 646 SPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMS 705 Query: 946 YAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGP----- 1000 +A LP T M P PG P PP PP + P Sbjct: 706 FA---PVLPPPSTPM----------------PTGPGQPAPPGQQ--PPPLAQPTPLPQVL 744 Query: 1001 -PQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRIPPLPPP 1052 PQ VP VP +P +G P +P Q P P ++PP PP Sbjct: 745 APQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPP 797 Score = 48.9 bits (115), Expect = 3e-05 Identities = 86/311 (27%), Positives = 103/311 (33%), Gaps = 53/311 (17%) Query: 770 AAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRML---- 825 A AA P +P S P PQ P A QP A P PV + + P L Sbjct: 641 ADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTA-APGLPVGSVPAPACPPSLQQHF 699 Query: 826 --TSGSHPQAIVSSSTPQ-------YPSAEQPTPQALYATVHQSY-PHHATQLHAHQPQP 875 + S + STP P +QP P A + Q P L QP P Sbjct: 700 PDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPL---QPVP 756 Query: 876 ATTPTGSQPQSQHAAPS---PVQHQAGQAPHLGSGQPQQ-------NLYHPGALTGTPPS 925 P P SQ AP+ P+Q L PQ + + G PP+ Sbjct: 757 PHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPA 816 Query: 926 LPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHP 985 LP P+A P P P Y LP A + A P PHP Sbjct: 817 LPDLPTATVP----PVPPPQYFSPAVILPS--------LAAPLPPASPALPLQAVKLPHP 864 Query: 986 PQVMLLHP-----PQSHGGPPQGAVPQSGVPALSA-STPSPYPYIGHPQGEQPGQAPGFP 1039 P L P P + P AV GV ALS S + P QP FP Sbjct: 865 PGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLP-------GQPVYPAAFP 917 Query: 1040 GGADDRIPPLP 1050 A +PP P Sbjct: 918 QMAPTDVPPSP 928 Score = 45.4 bits (106), Expect = 3e-04 Identities = 53/179 (29%), Positives = 70/179 (39%), Gaps = 21/179 (11%) Query: 352 LPQRVREGPRG----GVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSR 407 +P + E RG G+ ++ RPG R D P PG EA G P Sbjct: 10 VPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEP-PGLEAAEAPG-PQP 67 Query: 408 MSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA-VGRMYPPRSPKSAAPAPISASCPEP- 465 P +R L KT + R G + P P A V + P +P A P P+ P P Sbjct: 68 PQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGPD 127 Query: 466 PIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTL--EPQE 522 PI +AV T+ A P G A+ + E + EPGRT EP+E Sbjct: 128 PIAAAVETAPA----------PDGGPREEAAATVRKEDEGAAE-AKPEPGRTRRDEPEE 175 Score = 42.7 bits (99), Expect = 0.002 Identities = 93/362 (25%), Positives = 127/362 (35%), Gaps = 71/362 (19%) Query: 736 SVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSY-IPYNPQQ 794 S PG + G + S Q Q A+AP Q G P + + P P+ Sbjct: 1271 SDPGTSPPHLSTCGLGTGEESRQSQ-ANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPES 1329 Query: 795 FPGQP-AMMQPMAHYPSQPVFAPMLQSN--PRMLTSGSHPQAIVSSSTPQYPSAEQPTPQ 851 P P + + P A S P + L S P L S Q ++S + P P P P Sbjct: 1330 SPPLPLSSLPPEASQDSAP-YKDQLSSKEQPSFLAS----QQLLSQAGPSNPPGAPPAPL 1384 Query: 852 ALYATVHQSYPHH-ATQLHAHQPQPAT----------TPTG-------SQPQSQ-HAAPS 892 A + + P A + P+PA+ TP G SQP ++ H AP Sbjct: 1385 APSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPL 1444 Query: 893 PVQHQA-GQAPHLGSGQPQQNLYHPGALTGTPPSLP-PGPSAQSPQSSFPQPAAVYAIHH 950 VQ G AP + + PP P P P + +PQ + QPA + Sbjct: 1445 AVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPL----- 1499 Query: 951 QQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQ-GAVP--- 1006 LP A V + T +PP P P P L G PP+ G V Sbjct: 1500 --LP------AAVGAVSLATSQLPSPPLGPTVPPQPPSAL--ESDGEGPPPRVGFVDSTI 1549 Query: 1007 ------------QSGVPALSASTPSPYPY------IGHPQGEQPGQAPGFPGGADDRIPP 1048 Q VP SAS +P + +G+QP G D +PP Sbjct: 1550 KSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSE---VCGGDLALPP 1606 Query: 1049 LP 1050 +P Sbjct: 1607 VP 1608 Score = 42.0 bits (97), Expect = 0.003 Identities = 179/825 (21%), Positives = 273/825 (33%), Gaps = 171/825 (20%) Query: 1 MLKPQPL--QQPSQPQQPPPTQQAVARRPPGGTSPPNG---GLPGPLATSAAP-----PG 50 ML PQP+ QP+ P +P P Q + + +P + G P P A A P Sbjct: 985 MLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPV 1044 Query: 51 PPAA------------ASPCLGP--------VAAAGSGLRRGAEGILAPQPPPPQQHQER 90 PPAA A+P L P V+A+ + +L P PP Sbjct: 1045 PPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPP------L 1098 Query: 91 PGAAAIGSA------------RGQSTGKGPPQSPVFEGVYNNSRMLHFLTAVVGSTCDVK 138 PG I S Q++ PP P Y S + + +C+ Sbjct: 1099 PGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGGSDVTS--GKELSDSCE-- 1154 Query: 139 VKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRRE-----DIVDTMV---FKPSDV 190 G G + +++ R E A PR + D MV + + Sbjct: 1155 ---GAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDKMVECQLETHNH 1211 Query: 191 MLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDDYDLESDMSNG 250 +V F+ D + D+ + + + E + + Q + D D ++D G Sbjct: 1212 KMVTFK-FDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDMLSEDTDADRG 1270 Query: 251 WDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLAREI-----ES 305 DP + G+ T +S S P+ + N +R +A ES Sbjct: 1271 SDPGTSPP-HLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPES 1329 Query: 306 SPQYRLRIAMENDDGRTEEEKHSAVQR-QGSGRESPS-LASREGKYIPLPQRVREGPRGG 363 SP L E + SA + Q S +E PS LAS++ P P Sbjct: 1330 SPPLPLSSLPP------EASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAP 1383 Query: 364 VRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGP------------------ 405 + SS P +++LP G ++ P P S GGP Sbjct: 1384 LAPSS-----PPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAE 1438 Query: 406 SRMSPKAQRPLRG--AKTLSSPSNRPSGETSVP----PPPAVGRMYPPRSPKSAAPAPI- 458 + +P A +PL A +P + + S P PPPA P SP S P P Sbjct: 1439 THEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPA-----PEPSPHSGTPQPAL 1493 Query: 459 -----------------SASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISL 501 ++ P PP+G VP S + P P++ Sbjct: 1494 GQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPP---------PRVGF 1544 Query: 502 APTDVKELSTKEPGRTLEPQELARIAGKVPGLQNE--QKRFQLEELRKFGAQFKLQPSSS 559 + +K L K RTL QE + G E + F LE LR G Q + + Sbjct: 1545 VDSTIKSLDEKL--RTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLR--GDQPRSEVCGG 1600 Query: 560 PENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTE 619 + +L P P + + + V+ + G+ + T S E P + Sbjct: 1601 -DLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRD 1659 Query: 620 GPE--QPPPPCPSQTGSPPV----GLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLL 673 G + PS P ++ D+D G E S+ P P + Sbjct: 1660 GRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGE----SSAEP------PPSDMG 1709 Query: 674 SVNKSTSTPTSPGPRTHSTP---------SIPVLTAGQSGLYSPQ 709 +V S P + G R +P S P T G+ + S Q Sbjct: 1710 TVGGQASHPQTLGARALGSPRKRPEQQDVSSPAKTVGRFSVVSTQ 1754 Score = 41.6 bits (96), Expect = 0.004 Identities = 49/199 (24%), Positives = 66/199 (33%), Gaps = 16/199 (8%) Query: 874 QPATTPTGSQPQSQHAAPSPVQHQA---GQAPHLGSGQPQQNLYHPGALTGTPPSLPPGP 930 QP P P P+Q Q QA G +P++ L PP+LP Sbjct: 551 QPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLL---PPTLPTSA 607 Query: 931 SAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVM- 989 ++ + S+F Q + + A PP P PQ + Sbjct: 608 TSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLP 667 Query: 990 ---LLHPPQSHGGPPQGAVPQSGVP-ALSASTPSPY----PYIGHPQGEQPGQAPGFPGG 1041 P + G P G+VP P +L P P P + P P PG P Sbjct: 668 SLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMP-TGPGQPAP 726 Query: 1042 ADDRIPPLPPPGELKIVLA 1060 + PPL P L VLA Sbjct: 727 PGQQPPPLAQPTPLPQVLA 745 Score = 35.8 bits (81), Expect = 0.22 Identities = 39/149 (26%), Positives = 60/149 (40%), Gaps = 16/149 (10%) Query: 376 LSSLPPRGPHHLDNSSP-GPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRP-SGET 433 L +PP P +L +S G ++ + + + + P AQ P + P P +G Sbjct: 752 LQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGID 811 Query: 434 SVPP-----PPAVGRMYPPRSPKSAAPAPI--SASCPEPPIGSAVPTSSASIPVTSSVSD 486 +PP P A PP P+ +PA I S + P PP A+P + +P Sbjct: 812 GLPPALPDLPTATVPPVPP--PQYFSPAVILPSLAAPLPPASPALPLQAVKLP-----HP 864 Query: 487 PGVGSISPASPKISLAPTDVKELSTKEPG 515 PG P + AP + L+ PG Sbjct: 865 PGAPLAMPCRTIVPNAPATIPLLAVAPPG 893 Score = 35.0 bits (79), Expect = 0.38 Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 8/85 (9%) Query: 12 QPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAA-----SPCLGPVAAAG 66 +P P P A+ +P +P + G P P+ T P P AAA +P GP A Sbjct: 92 RPAAPAPA--ALVAQPGAPGAPADAG-PEPVGTQEPGPDPIAAAVETAPAPDGGPREEAA 148 Query: 67 SGLRRGAEGILAPQPPPPQQHQERP 91 + +R+ EG +P P + ++ P Sbjct: 149 ATVRKEDEGAAEAKPEPGRTRRDEP 173 Score = 35.0 bits (79), Expect = 0.38 Identities = 38/150 (25%), Positives = 53/150 (35%), Gaps = 18/150 (12%) Query: 910 QQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQ---- 965 QQN+ H G + P+ ++P+SS P P + Q + + + Sbjct: 1302 QQNVLHTGKRWFIICPVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSF 1361 Query: 966 -AHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYI 1024 A Q A P PGAP P P S PP A+PQ G +++ P P Sbjct: 1362 LASQQLLSQAGPSNPPGAPPAPLA-----PSS---PPVTALPQDGAAPATSTMPEPASGT 1413 Query: 1025 GHPQGEQPGQAPGFPGGADDRIPPLPPPGE 1054 G PG P G + P E Sbjct: 1414 ASQAG-----GPGTPQGLTSELETSQPLAE 1438 Score = 33.1 bits (74), Expect = 1.4 Identities = 60/249 (24%), Positives = 90/249 (36%), Gaps = 50/249 (20%) Query: 315 MENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGPRGG-VRCSSSRGGR 373 ME + + S G R+ +AS +PQ V R V + GG Sbjct: 1636 MEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGE 1695 Query: 374 PGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGET 433 G SS P P S+ + G S GA+ L SP RP + Sbjct: 1696 AGESSAEP------------PPSDMGTVGGQASHPQTL------GARALGSPRKRPEQQD 1737 Query: 434 SVPPPPAVGR-----------MYPPRSPKSAAPAPI----SASCPEPPIGSAVPTSSASI 478 P VGR + P S + +AP + + S P+ + +++SI Sbjct: 1738 VSSPAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSI 1797 Query: 479 ------PVTSSVSDPGVGSISPASPKISL------APTDVKELST--KEPGR--TLEPQE 522 PV+S D G + P + SL A VK+ + + P R +L P+ Sbjct: 1798 EVGVGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPET 1857 Query: 523 LARIAGKVP 531 +R+ KVP Sbjct: 1858 PSRVGMKVP 1866 Score = 32.0 bits (71), Expect = 3.2 Identities = 50/200 (25%), Positives = 71/200 (35%), Gaps = 31/200 (15%) Query: 622 EQPPPPCPSQTGSPPVGLIKGE-DKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTS 680 E P P P + P+ + E +D P +Q+ F ++ LLS ++ Sbjct: 1320 EHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSK----EQPSFLASQQLLSQAGPSN 1375 Query: 681 TPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQA-----PQMYPYPVSN 735 P +P P + S PV Q G + S +P+ G A QA PQ + Sbjct: 1376 PPGAP-PAPLAPSSPPVTALPQDG--AAPATSTMPEPASGTASQAGGPGTPQGLTSELET 1432 Query: 736 SVP---------GQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSS 786 S P Q G P + + ASAP PP +P+S Sbjct: 1433 SQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAP-----REPLPPPAPEPSPHSG 1487 Query: 787 YIPYNPQQFPGQPAMMQPMA 806 PQ GQPA + P A Sbjct: 1488 ----TPQPALGQPAPLLPAA 1503 Score = 31.6 bits (70), Expect = 4.2 Identities = 20/56 (35%), Positives = 20/56 (35%) Query: 2 LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASP 57 L PQP P P PT PP T PP LP P PP A P Sbjct: 944 LPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALP 999 Score = 30.8 bits (68), Expect = 7.1 Identities = 29/103 (28%), Positives = 41/103 (39%), Gaps = 10/103 (9%) Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464 P SP P A + P +P PP P R+ APA I Sbjct: 831 PQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATI------ 884 Query: 465 PPIGSAVPTSSASIPVTSSVSD-PGVGSISPASPKISLAPTDV 506 P+ + P A++ + S+V+ PG A P+ +APTDV Sbjct: 885 -PLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQ--MAPTDV 924 Score = 30.4 bits (67), Expect = 9.2 Identities = 23/74 (31%), Positives = 26/74 (35%), Gaps = 9/74 (12%) Query: 13 PQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRG 72 P P T Q + PP PP LP PP P P L P R Sbjct: 925 PPSPHHTVQNMRATPPQPALPPQPTLP---PQPVLPPQPTLPPQPVLPPQPT------RP 975 Query: 73 AEGILAPQPPPPQQ 86 + +L PQP P Q Sbjct: 976 PQPVLPPQPMLPPQ 989 Score = 30.4 bits (67), Expect = 9.2 Identities = 27/76 (35%), Positives = 29/76 (38%), Gaps = 16/76 (21%) Query: 10 PSQPQQPP-PTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSG 68 P QP PP PT PP T PP LP P T PP P P L P Sbjct: 939 PPQPALPPQPTLPPQPVLPPQPTLPPQPVLP-PQPT--RPPQPVLPPQPMLPP------- 988 Query: 69 LRRGAEGILAPQPPPP 84 + +L PQP P Sbjct: 989 -----QPVLPPQPALP 999 >gi|112734870 hypothetical protein LOC57648 [Homo sapiens] Length = 1094 Score = 72.0 bits (175), Expect = 3e-12 Identities = 167/711 (23%), Positives = 236/711 (33%), Gaps = 113/711 (15%) Query: 305 SSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGPRGGV 364 SSPQ R R + D + + + GS S + + + V P+GG Sbjct: 400 SSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGG- 458 Query: 365 RCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSS 424 S RG G S+ +S + G G S K +RP + S Sbjct: 459 ---SGRGSPSGGSTA---------EASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHS 506 Query: 425 PSNR----PSGETSVPPPPAVGRMYPPRSPK----SAAPAPISASCPEPPIGSAVPTSSA 476 R P G +PP P R P+ P+ + +A CP P S VP S Sbjct: 507 LHQRGLAVPDGPLGLPPKPE--RKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLS- 563 Query: 477 SIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNE 536 PG P SP+ +L+P+ + P TL P+ LA PG Sbjct: 564 ----------PGGSRRPPRSPERTLSPSSGYSSQSGTP--TLPPKGLAGPPAS-PGKAQP 610 Query: 537 QKRFQLEELRKFGAQFKLQPSSSPENSLDPFP-----PRIL------------------- 572 K ++ LR GA +S +S DP P P+IL Sbjct: 611 PKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPF 670 Query: 573 ---KEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKP-----PLAPSGGTEGPEQP 624 +P+ L + PVS+ T++ P PL S + P Sbjct: 671 SPPPSKPRSPNPAAPALAAPAVVPGPVST-TDASPQSPPTPQTTLTPLQESPVISKDQSP 729 Query: 625 PPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTL-NPNAKEFNPTKPLLSVNKSTSTPT 683 PP P PP K E E P A + + L +PN + P P + S Sbjct: 730 PPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPN---WPPPPPPAPEEQDLSMAD 786 Query: 684 SPGPRTHSTPSIPVLTAGQSGLYSPQYIS---------YIPQIHMGPAVQAPQMYPYPV- 733 P P AG SG SP+ +S QI + P P P Sbjct: 787 FPPPEEAFFSVASPEPAGPSG--SPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAP 844 Query: 734 SNSVPGQQGKYRG------AKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSY 787 ++S PG K +KG PP R D P P ++Q P + Sbjct: 845 ASSAPGHVAKLPQKEPVGCSKGGGPP-REDVGAPLVTPSLLQMVRLRSVGAPGGAPTPAL 903 Query: 788 IPYNPQQFPGQPAMMQPMAHYPSQPVFAPM--LQSNPRMLTSGSHPQAIVSSSTPQ-YPS 844 P PQ+ P + A+ + PV AP L + R+ +SS+ P P Sbjct: 904 GPSAPQK-PLRRALSG-----RASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPE 957 Query: 845 AEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHL 904 AE PQ+ +T + + +L +P T Q S + + QAP Sbjct: 958 AEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKK 1017 Query: 905 GSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPH 955 P P G PP P S+P+ + A LPH Sbjct: 1018 SPKAPPPVARKPS--VGVPPPASP---------SYPRAEPLTAPPTNGLPH 1057 Score = 54.3 bits (129), Expect = 6e-07 Identities = 155/672 (23%), Positives = 212/672 (31%), Gaps = 137/672 (20%) Query: 467 IGSAVPTSSASIPVTSSVSDPGV----GSISPASPKISLAPTDVKELSTKEPGRTLEPQE 522 +G + T + + S++ PG+ G P SP +S++P LS P L P Sbjct: 306 VGRSTGTRAPPLTRPMSLAVPGLTGGAGPAEPLSPAMSISP-QATYLSKLIPHAVLPPTV 364 Query: 523 LARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKE 582 G+ LR S + SL F + +P+ + Sbjct: 365 DVVALGRC-------------SLRTLSRCSLHSASPASVRSLGRFSS-VSSPQPRSRHPS 410 Query: 583 VDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEG-PEQ--------PPPPCPSQTG 633 +S S S VSD L+ GG+EG PE PPP S G Sbjct: 411 -----SSSDTWSHSQSSDTIVSDGST---LSSKGGSEGQPESSTASNSVVPPPQGGSGRG 462 Query: 634 SPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTP 693 SP G AE ++ + + + L + + P P RTHS Sbjct: 463 SP----------SGGSTAEASDTLSIRSSGQLSGRSVSLRKLKR----PPPPPRRTHSLH 508 Query: 694 SIPVLTA-GQSGLYSPQYISYIPQIHMGPAVQ------APQMYPYPVSNSVPGQQGKYRG 746 + G GL PQ+ P A P P ++ VPG Sbjct: 509 QRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLS----- 563 Query: 747 AKGSLPPQRSDQ--------HQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQF--- 795 GS P RS + + S P + AGPP A+P + P P++ Sbjct: 564 PGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPP---ASPGKAQPP-KPERVTSL 619 Query: 796 --PGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTS-------GSHPQAIVS-SSTPQYPSA 845 PG + S AP +S P++LT HP+ S P P + Sbjct: 620 RSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRS 679 Query: 846 EQPTPQALYATV------------HQSYPHHATQLHAHQPQPATT----PTGSQPQSQHA 889 P AL A QS P T L Q P + P S P S H Sbjct: 680 PNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHP 739 Query: 890 APSPVQHQ--AGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQS-PQSSFPQPAAVY 946 P P + +AP S ++ L P PP PP P Q + FP P + Sbjct: 740 PPPPTKKPEVVVEAPS-ASETAEEPLQDPN----WPPPPPPAPEEQDLSMADFPPPEEAF 794 Query: 947 AIHHQQLPHG-----------FTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQ 995 P G + + T +Q + PPP P AP P H + Sbjct: 795 FSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAK 854 Query: 996 SHGGPPQGAVPQSGVPALSASTPSPYP---------YIGHPQG-EQPGQAPGFP-----G 1040 P G G P P P +G P G P P P Sbjct: 855 LPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRR 914 Query: 1041 GADDRIPPLPPP 1052 R P+P P Sbjct: 915 ALSGRASPVPAP 926 Score = 38.9 bits (89), Expect = 0.026 Identities = 32/116 (27%), Positives = 46/116 (39%), Gaps = 10/116 (8%) Query: 5 QPLQQPSQPQQPPPTQQ----AVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60 +PLQ P+ P PPP + ++A PP + + P P S + P +SP Sbjct: 762 EPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGS---PELVSSPAAS 818 Query: 61 PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSAR---GQSTGKGPPQSPV 113 +A ++ P PP P PG A + G S G GPP+ V Sbjct: 819 SSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDV 874 Score = 35.0 bits (79), Expect = 0.38 Identities = 31/117 (26%), Positives = 43/117 (36%), Gaps = 10/117 (8%) Query: 3 KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPG--PLATSAAPPGPPAAASPCLG 60 KP+ QQP P+ P A P +P N +PG P + P P SP G Sbjct: 524 KPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSG 583 Query: 61 PVAAAGS------GLRRGAEGILAPQPPPPQQ--HQERPGAAAIGSARGQSTGKGPP 109 + +G+ GL QPP P++ PGA+ S + P Sbjct: 584 YSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDP 640 Score = 32.7 bits (73), Expect = 1.9 Identities = 31/114 (27%), Positives = 42/114 (36%), Gaps = 17/114 (14%) Query: 10 PSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAA----PPGPPAAASPCL-GPVAA 64 PS+P+ P P A+A +PGP++T+ A PP P +P PV + Sbjct: 674 PSKPRSPNPAAPALAAPAV---------VPGPVSTTDASPQSPPTPQTTLTPLQESPVIS 724 Query: 65 AGSGLRRGAEGILAPQPPP---PQQHQERPGAAAIGSARGQSTGKGPPQSPVFE 115 P PPP P+ E P A+ Q PP P E Sbjct: 725 KDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPE 778 Score = 30.8 bits (68), Expect = 7.1 Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 5/80 (6%) Query: 33 PPNGGLPGPLATSAAPPGPPAAASPCL-GPVAAAGSGLRRGAEGILAPQPPPPQQHQERP 91 PP+ +P P + + P P A+P L P G A +PQ PP Q P Sbjct: 661 PPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDA----SPQSPPTPQTTLTP 716 Query: 92 GAAAIGSARGQSTGKGPPQS 111 + ++ QS PP S Sbjct: 717 LQESPVISKDQSPPPSPPPS 736 >gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 [Homo sapiens] Length = 2231 Score = 71.6 bits (174), Expect = 4e-12 Identities = 133/524 (25%), Positives = 182/524 (34%), Gaps = 108/524 (20%) Query: 574 EEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG 633 + P G ++ LLTS SP+ ++ S E P AP P+ + G Sbjct: 352 QHPSGATPTLNQLLTSP---SPMM-RSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407 Query: 634 SPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGP---RTH 690 G KD G A+ S A++ + P +S P +PGP R+ Sbjct: 408 GQQAAAGMGLGKDMG--AQYAAASPAWAAAQQ--RSHPAMS-------PGTPGPTMGRSQ 456 Query: 691 STPSIPVLTA-------GQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK 743 +P P++ G + PQ S P GP PQ YP + PG Sbjct: 457 GSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPP--GPQRYPIGIQGRTPGAMAG 514 Query: 744 YRGAKGSLPPQR-----------------SDQHQPASAPPMMQAAAAAGPPLVAATPYSS 786 + + +PPQ S Q QP PP Q Sbjct: 515 MQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQ----------------- 557 Query: 787 YIPYNPQQ-FPGQPAMMQPMAHYPSQPVFAPMLQSNPRM-LTSGSHPQAIVSSSTPQYPS 844 Y+P QQ + Q M Q SQP AP ++ + L P SS P Sbjct: 558 YLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERP-----SSLPDLSG 612 Query: 845 AEQPTPQALYATVHQSY-PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPH 903 + P AT+ + +T Q PA +P S HA+P G +P Sbjct: 613 SIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPF-----SPHASPHLSSIPGGPSPS 667 Query: 904 -----LGSGQPQQNLYHPGALTGTP-PSLPPGPSAQSPQSSFPQPAAVYAIHHQQLP--H 955 +GS Q + P ++ G+ P PPG +QS SS P A+ +P Sbjct: 668 PVGSPVGSNQSRSGPISPASIPGSQMPPQPPG--SQSESSSHP------ALSQSPMPQER 719 Query: 956 GF-----TNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHG--GP------PQ 1002 GF N QTG + +P P PG + S G GP PQ Sbjct: 720 GFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQ 779 Query: 1003 GAVPQ----SGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGA 1042 G + SGVP+ S S P P I + GQ P P GA Sbjct: 780 GNYSRPPAYSGVPSASYSGPGPGMGIS-ANNQMHGQGPSQPCGA 822 Score = 63.9 bits (154), Expect = 8e-10 Identities = 163/776 (21%), Positives = 252/776 (32%), Gaps = 105/776 (13%) Query: 321 RTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLP 380 R +E +AV + + S SR+G + + Q G+ SSS +P +S Sbjct: 869 RKAQEAAAAVMQAAAN----SAQSRQGSFPGMNQ-------SGLMASSSPYSQPMNNS-- 915 Query: 381 PRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA 440 L N+ P S A + + A G L P E P P + Sbjct: 916 ----SSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPES 971 Query: 441 VGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKIS 500 + S P P + P P S+ SS + S+S PG +P+SPK S Sbjct: 972 KSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDESDSISSPGWPK-TPSSPKSS 1030 Query: 501 LAPTDVKELST-----KEPGRTL------------------------EPQELARI---AG 528 + T ++++ EP R L +P +L R+ Sbjct: 1031 SSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVK 1090 Query: 529 KVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLT 588 ++ GL K ++ R+ + SSS +SL K++ + L Sbjct: 1091 EIGGLAQVNKN---KKWRELATNLNVGTSSSAASSL--------------KKQYIQYLFA 1133 Query: 589 SE---PMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDK 645 E G + S D + +P L P P P TGS + + G+ K Sbjct: 1134 FECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLK 1193 Query: 646 DEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNK--STSTPTSPGPRTHSTPSIPVLTAGQS 703 P + + T + +SV+ S + +S R TP+ P Q Sbjct: 1194 PPTPASTPHGQMTPMQGGR-----SSTISVHDPFSDVSDSSFPKRNSMTPNAPY----QQ 1244 Query: 704 GLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLP-PQRSDQHQPA 762 G+ P + +P P P+ VPG + +G +P D + + Sbjct: 1245 GMSMPDVMGRMP--------YEPNKDPFGGMRKVPGSSEPFM-TQGQMPNSSMQDMYNQS 1295 Query: 763 SAPPMMQAAAAAGPPLVAATPYS-SYIPYNPQQFPGQ-PAMMQPMAHYPSQPVFAPMLQS 820 + M Y + PY QQ+PGQ P QP + QP P Q Sbjct: 1296 PSGAMSNLGMGQRQQFPYGASYDRRHEPYG-QQYPGQGPPSGQP-PYGGHQPGLYPQ-QP 1352 Query: 821 NPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYP-HHATQLHAHQPQPATTP 879 N + G + Y Q +Y SY + P P + Sbjct: 1353 NYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRE 1412 Query: 880 TGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSF 939 P P Q G S PQQN++ P GP + + Sbjct: 1413 RMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPY 1472 Query: 940 P--QPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSH 997 P + Q++ H +HV+Q +A+ P PPQ PP Sbjct: 1473 PGMNRTDDMMVPDQRINHESQWPSHVSQRQPYMSSSASMQP---ITRPPQPSYQTPPSLP 1529 Query: 998 GGPPQGAVPQSGVPAL-SASTPSPYPYIGHPQGEQPGQAPGFPGGADDRIPPLPPP 1052 + P S +L + +PS P++ P + P P PP PPP Sbjct: 1530 NHISRAPSPASFQRSLENRMSPSKSPFL--PSMKMQKVMPTVPTSQVTGPPPQPPP 1583 Score = 40.8 bits (94), Expect = 0.007 Identities = 138/618 (22%), Positives = 188/618 (30%), Gaps = 155/618 (25%) Query: 533 LQNEQKRFQLEELRKFGAQFKLQPSSSP---ENSLD------PFPPRILKEEPKGKEKEV 583 LQ + +FQ ++ ++ Q + Q P NSL P P +++ G K+ Sbjct: 48 LQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDS 107 Query: 584 DGLLTSEPMGSPVSSKTESVSDKEDKPPLA----------PSGGTEGPEQPPPPCPSQTG 633 ++P G P+ SK D++D PP P G G +QPP P G Sbjct: 108 AAGGQADPPGPPLLSKP---GDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGG 164 Query: 634 SPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTP 693 GP A EFN ++ P S GP + P Sbjct: 165 --------------GPAA-----------VPEFNNYY-------GSAAPASGGPGGRAGP 192 Query: 694 SIPV----LTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQ-------- 741 + G ++S + M P + + YP N PG Sbjct: 193 CFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGG 252 Query: 742 -------GKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSY---IPYN 791 G G G A A AAAAAG SS + + Sbjct: 253 GGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSS 312 Query: 792 PQQFPGQPAMMQPM---AHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQP 848 P+Q G MM P A S+ R HP S +TP Sbjct: 313 PRQ-QGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHP----SGATPTLNQL-LT 366 Query: 849 TPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQ 908 +P + + SYP +++ A P SQPQSQ AA A +G G+ Sbjct: 367 SPSPMMRSYGGSYPEYSSP-------SAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGK 419 Query: 909 PQ--------------QNLYHPGALTGTP-PSL------PPGPSA--------------Q 933 Q HP GTP P++ P P Sbjct: 420 DMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHS 479 Query: 934 SPQSSFPQPAAVYA-IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPH------------- 979 PQ S P P Y Q+ P G A +Q PP + Sbjct: 480 QPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQ 539 Query: 980 -------PGAPH-PPQVMLLHPPQSHGGPPQGAVPQSGV-----PALSASTPSPYPYIGH 1026 P PH PPQ L PQ + Q G P L+ P+ + + Sbjct: 540 QPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPN-HEDLNL 598 Query: 1027 PQGEQPGQAPGFPGGADD 1044 Q E+P P G DD Sbjct: 599 IQQERPSSLPDLSGSIDD 616 Score = 32.7 bits (73), Expect = 1.9 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 8/80 (10%) Query: 380 PPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPP- 438 PP P+H+ + P P S R + +RMSP L K P+ + + PPP Sbjct: 1525 PPSLPNHISRA-PSPASFQRSLE---NRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQ 1580 Query: 439 -PAVGR--MYPPRSPKSAAP 455 P + R +PP S +++ P Sbjct: 1581 PPPIRREITFPPGSVEASQP 1600 Score = 32.3 bits (72), Expect = 2.4 Identities = 40/135 (29%), Positives = 45/135 (33%), Gaps = 26/135 (19%) Query: 5 QPLQQPSQPQQPPPTQQAVARRPPGGT--------SPPNGGLPGPLATSAA-PPGPPAA- 54 Q QQ Q QQ P + GG P +GG A A PPGPP Sbjct: 63 QQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS 122 Query: 55 -------ASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAI-------GSAR 100 A P +G AG G L Q PP G AA+ GSA Sbjct: 123 KPGDEDDAPPKMG--EPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA 180 Query: 101 GQSTGKGPPQSPVFE 115 S G G P F+ Sbjct: 181 PASGGPGGRAGPCFD 195 Score = 31.6 bits (70), Expect = 4.2 Identities = 31/114 (27%), Positives = 39/114 (34%), Gaps = 9/114 (7%) Query: 9 QPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGP-------PAAASPCLGP 61 Q P PT + P G P + SA PP P AA + G Sbjct: 350 QNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQ 409 Query: 62 VAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK--GPPQSPV 113 AAAG GL + A P Q+R A G + G+ G P P+ Sbjct: 410 QAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPM 463 Score = 30.8 bits (68), Expect = 7.1 Identities = 21/70 (30%), Positives = 29/70 (41%), Gaps = 4/70 (5%) Query: 36 GGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGIL----APQPPPPQQHQERP 91 G G A P+ A+P L + + S + R G +P PPP Q + Sbjct: 338 GSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQS 397 Query: 92 GAAAIGSARG 101 AAA G+A G Sbjct: 398 QAAAAGAAAG 407 >gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 [Homo sapiens] Length = 2178 Score = 71.6 bits (174), Expect = 4e-12 Identities = 133/524 (25%), Positives = 182/524 (34%), Gaps = 108/524 (20%) Query: 574 EEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG 633 + P G ++ LLTS SP+ ++ S E P AP P+ + G Sbjct: 352 QHPSGATPTLNQLLTSP---SPMM-RSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407 Query: 634 SPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGP---RTH 690 G KD G A+ S A++ + P +S P +PGP R+ Sbjct: 408 GQQAAAGMGLGKDMG--AQYAAASPAWAAAQQ--RSHPAMS-------PGTPGPTMGRSQ 456 Query: 691 STPSIPVLTA-------GQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK 743 +P P++ G + PQ S P GP PQ YP + PG Sbjct: 457 GSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPP--GPQRYPIGIQGRTPGAMAG 514 Query: 744 YRGAKGSLPPQR-----------------SDQHQPASAPPMMQAAAAAGPPLVAATPYSS 786 + + +PPQ S Q QP PP Q Sbjct: 515 MQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQ----------------- 557 Query: 787 YIPYNPQQ-FPGQPAMMQPMAHYPSQPVFAPMLQSNPRM-LTSGSHPQAIVSSSTPQYPS 844 Y+P QQ + Q M Q SQP AP ++ + L P SS P Sbjct: 558 YLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERP-----SSLPDLSG 612 Query: 845 AEQPTPQALYATVHQSY-PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPH 903 + P AT+ + +T Q PA +P S HA+P G +P Sbjct: 613 SIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPF-----SPHASPHLSSIPGGPSPS 667 Query: 904 -----LGSGQPQQNLYHPGALTGTP-PSLPPGPSAQSPQSSFPQPAAVYAIHHQQLP--H 955 +GS Q + P ++ G+ P PPG +QS SS P A+ +P Sbjct: 668 PVGSPVGSNQSRSGPISPASIPGSQMPPQPPG--SQSESSSHP------ALSQSPMPQER 719 Query: 956 GF-----TNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHG--GP------PQ 1002 GF N QTG + +P P PG + S G GP PQ Sbjct: 720 GFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQ 779 Query: 1003 GAVPQ----SGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGA 1042 G + SGVP+ S S P P I + GQ P P GA Sbjct: 780 GNYSRPPAYSGVPSASYSGPGPGMGIS-ANNQMHGQGPSQPCGA 822 Score = 57.4 bits (137), Expect = 7e-08 Identities = 174/802 (21%), Positives = 264/802 (32%), Gaps = 113/802 (14%) Query: 331 QRQGSGRESPSLA--------SREGKYIPLPQRVREGPRGGVRCSSSRG----------G 372 Q SG P ++ SR Y +P GP G+ S++ G Sbjct: 762 QSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCG 821 Query: 373 RPGLSSLPPRG----PHHLDNSSPGPGSEARGINGGPSRMSP------KAQRPLRGAKTL 422 L +P G P + SS P S GGP P KAQ A Sbjct: 822 AVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAA-AAVMQ 880 Query: 423 SSPSNRPSGETSVPPPPAVGRMY---PPRSPKSAAPAPISASCPEPPIGSAVPTSSASIP 479 ++ ++ S + S P G M P P + + + ++ P P S A Sbjct: 881 AAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAP--------PYSMAPAM 932 Query: 480 VTSSVSDPGVGSI-SPASPKISLA-PTDVKELSTKEPGRTLEPQELARIAG----KVPGL 533 V SS + G+ + SP K+ L D KE T +P + + G KV L Sbjct: 933 VNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYEL 992 Query: 534 QNE-QKRFQLEELRKFGAQFKLQPSSSP---ENSLDPFPPRILKEEPKG-----KEKEVD 584 NE +++ ++ F + SS P + LD F + +E G K K+ Sbjct: 993 GNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWR 1052 Query: 585 GLLTSEPMGSPVSSKTE--------------SVSDKEDKPP-LAPSGGTEGPEQPPPPCP 629 L T+ +G+ S+ + + E+ PP + +G T+ + PP P Sbjct: 1053 ELATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSP 1112 Query: 630 SQTGS---PPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSP- 685 + +GS P G + V +K T P + P+ ST + P Sbjct: 1113 ANSGSLQGPQTPQSTGSN-SMAEVPGDLKPPT--PASTPHGQMTPMQGGRSSTISVHDPF 1169 Query: 686 --------GPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSV 737 R TP+ P Q G+ P + +P P P+ V Sbjct: 1170 SDVSDSSFPKRNSMTPNAPY----QQGMSMPDVMGRMP--------YEPNKDPFGGMRKV 1217 Query: 738 PGQQGKYRGAKGSLP-PQRSDQHQPASAPPMMQAAAAAGPPLVAATPYS-SYIPYNPQQF 795 PG + +G +P D + + + M Y + PY QQ+ Sbjct: 1218 PGSSEPFM-TQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYG-QQY 1275 Query: 796 PGQ-PAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALY 854 PGQ P QP + QP P Q N + G + Y Q +Y Sbjct: 1276 PGQGPPSGQP-PYGGHQPGLYPQ-QPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMY 1333 Query: 855 ATVHQSYP-HHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNL 913 SY + P P + P P Q G S PQQN+ Sbjct: 1334 NQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNM 1393 Query: 914 YHPGALTGTPPSLPPGPSAQSPQSSFP--QPAAVYAIHHQQLPHGFTNMAHVTQAHVQTG 971 + P GP + +P + Q++ H +HV+Q Sbjct: 1394 WAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPYMS 1453 Query: 972 ITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPAL-SASTPSPYPYIGHPQGE 1030 +A+ P PPQ PP + P S +L + +PS P++ P + Sbjct: 1454 SSASMQP---ITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPFL--PSMK 1508 Query: 1031 QPGQAPGFPGGADDRIPPLPPP 1052 P P PP PPP Sbjct: 1509 MQKVMPTVPTSQVTGPPPQPPP 1530 Score = 40.8 bits (94), Expect = 0.007 Identities = 138/618 (22%), Positives = 188/618 (30%), Gaps = 155/618 (25%) Query: 533 LQNEQKRFQLEELRKFGAQFKLQPSSSP---ENSLD------PFPPRILKEEPKGKEKEV 583 LQ + +FQ ++ ++ Q + Q P NSL P P +++ G K+ Sbjct: 48 LQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDS 107 Query: 584 DGLLTSEPMGSPVSSKTESVSDKEDKPPLA----------PSGGTEGPEQPPPPCPSQTG 633 ++P G P+ SK D++D PP P G G +QPP P G Sbjct: 108 AAGGQADPPGPPLLSKP---GDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGG 164 Query: 634 SPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTP 693 GP A EFN ++ P S GP + P Sbjct: 165 --------------GPAA-----------VPEFNNYY-------GSAAPASGGPGGRAGP 192 Query: 694 SIPV----LTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQ-------- 741 + G ++S + M P + + YP N PG Sbjct: 193 CFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGG 252 Query: 742 -------GKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSY---IPYN 791 G G G A A AAAAAG SS + + Sbjct: 253 GGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSS 312 Query: 792 PQQFPGQPAMMQPM---AHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQP 848 P+Q G MM P A S+ R HP S +TP Sbjct: 313 PRQ-QGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHP----SGATPTLNQL-LT 366 Query: 849 TPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQ 908 +P + + SYP +++ A P SQPQSQ AA A +G G+ Sbjct: 367 SPSPMMRSYGGSYPEYSSP-------SAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGK 419 Query: 909 PQ--------------QNLYHPGALTGTP-PSL------PPGPSA--------------Q 933 Q HP GTP P++ P P Sbjct: 420 DMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHS 479 Query: 934 SPQSSFPQPAAVYA-IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPH------------- 979 PQ S P P Y Q+ P G A +Q PP + Sbjct: 480 QPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQ 539 Query: 980 -------PGAPH-PPQVMLLHPPQSHGGPPQGAVPQSGV-----PALSASTPSPYPYIGH 1026 P PH PPQ L PQ + Q G P L+ P+ + + Sbjct: 540 QPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPN-HEDLNL 598 Query: 1027 PQGEQPGQAPGFPGGADD 1044 Q E+P P G DD Sbjct: 599 IQQERPSSLPDLSGSIDD 616 Score = 32.7 bits (73), Expect = 1.9 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 8/80 (10%) Query: 380 PPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPP- 438 PP P+H+ + P P S R + +RMSP L K P+ + + PPP Sbjct: 1472 PPSLPNHISRA-PSPASFQRSLE---NRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQ 1527 Query: 439 -PAVGR--MYPPRSPKSAAP 455 P + R +PP S +++ P Sbjct: 1528 PPPIRREITFPPGSVEASQP 1547 Score = 32.3 bits (72), Expect = 2.4 Identities = 40/135 (29%), Positives = 45/135 (33%), Gaps = 26/135 (19%) Query: 5 QPLQQPSQPQQPPPTQQAVARRPPGGT--------SPPNGGLPGPLATSAA-PPGPPAA- 54 Q QQ Q QQ P + GG P +GG A A PPGPP Sbjct: 63 QQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS 122 Query: 55 -------ASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAI-------GSAR 100 A P +G AG G L Q PP G AA+ GSA Sbjct: 123 KPGDEDDAPPKMG--EPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA 180 Query: 101 GQSTGKGPPQSPVFE 115 S G G P F+ Sbjct: 181 PASGGPGGRAGPCFD 195 Score = 31.6 bits (70), Expect = 4.2 Identities = 31/114 (27%), Positives = 39/114 (34%), Gaps = 9/114 (7%) Query: 9 QPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGP-------PAAASPCLGP 61 Q P PT + P G P + SA PP P AA + G Sbjct: 350 QNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQ 409 Query: 62 VAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK--GPPQSPV 113 AAAG GL + A P Q+R A G + G+ G P P+ Sbjct: 410 QAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPM 463 Score = 30.8 bits (68), Expect = 7.1 Identities = 21/70 (30%), Positives = 29/70 (41%), Gaps = 4/70 (5%) Query: 36 GGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGIL----APQPPPPQQHQERP 91 G G A P+ A+P L + + S + R G +P PPP Q + Sbjct: 338 GSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQS 397 Query: 92 GAAAIGSARG 101 AAA G+A G Sbjct: 398 QAAAAGAAAG 407 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 70.9 bits (172), Expect = 6e-12 Identities = 128/566 (22%), Positives = 197/566 (34%), Gaps = 71/566 (12%) Query: 394 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRP------SGETSVPPPPAVGRMYPP 447 P +A GP+ +PK P + S+ P S T+ P P Sbjct: 197 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 256 Query: 448 RSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVK 507 +PK AP P P A T+ P T+ + +P +PK APT Sbjct: 257 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPT--- 312 Query: 508 ELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPF 567 + KEP T P+E K P ++ + A K P++ E + Sbjct: 313 --TPKEPAPT-TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA---- 365 Query: 568 PPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP 627 P KE KE EP +P ++K+ + KE AP+ P P P Sbjct: 366 -PTTPKEPAPTTTKEPSPTTPKEP--APTTTKSAPTTTKEP----APTTTKSAPTTPKEP 418 Query: 628 CPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNK--STSTPTSP 685 P+ T P K+ P + T P +P + K + +TP P Sbjct: 419 SPTTTKEP----APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 474 Query: 686 GPRT--HSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK 743 P T + P+ P +P+ ++ P PA P+ ++ + P + Sbjct: 475 APTTPKETAPTTPKKLTPT----TPEKLA--PTTPEKPAPTTPE----ELAPTTPEE--- 521 Query: 744 YRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQ 803 P + +PA P +AAA P A T P P+ +PA Sbjct: 522 ---------PTPTTPEEPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPK----EPAPTT 566 Query: 804 PMAHYPSQPV-FAPMLQSNPRMLT-SGSHPQAIVSSST--PQYPSAEQPTPQALYATVHQ 859 P P+ P AP P T P+ + ++T P + ++P P T Sbjct: 567 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA-P 625 Query: 860 SYPHHATQLHAHQPQPATTPTGSQPQS-QHAAPSPVQHQAGQ--APHLGSGQPQQNLYHP 916 + P +P P TTP G+ P + + AP+ + A + AP G P Sbjct: 626 TTPKEPAPTTPKEPAP-TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 684 Query: 917 GALT--GTPPSLPPGPSAQSPQSSFP 940 T T P+ P P+ +P+ P Sbjct: 685 APTTPKETAPTTPKEPAPTTPKKPAP 710 Score = 67.8 bits (164), Expect = 5e-11 Identities = 124/579 (21%), Positives = 183/579 (31%), Gaps = 72/579 (12%) Query: 419 AKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASI 478 +K L+ P+ P ET+ P + P+ P P +++ P+ P PT+ S Sbjct: 191 SKVLAKPT--PKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEP----TPTTIKSA 240 Query: 479 PVTSSVSDPGVGSISPASPKISLAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQN 535 P T PA APT KE +TKEP T P+E A K P Sbjct: 241 PTTPK---------EPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKEPA--- 287 Query: 536 EQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSP 595 S+P +P P K P KE EP +P Sbjct: 288 -----------------PTTTKSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEP--TP 327 Query: 596 VSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG-SPPVGLIKGEDKDEGPVAEQV 654 + K + + KE P P++P P P + + P K+ P + Sbjct: 328 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 387 Query: 655 KKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYI 714 T +A + + +TP P P T P+ T + +P+ Sbjct: 388 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTTPK--KPA 443 Query: 715 PQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAA 774 P PA P+ P P + P A + P + + P + A Sbjct: 444 PTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTPEKLAPT 501 Query: 775 GPPLVAATPYSSYIPYNPQQ----FPGQPAMMQPMAHYPSQPVF-APMLQSNPRMLTSGS 829 P A T P P++ P +PA P A P+ P AP P T Sbjct: 502 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 561 Query: 830 HPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHA 889 + P P PT T+ + P + + P TT + Sbjct: 562 PAPTTPKETAPTTPKGTAPT------TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 615 Query: 890 APSPVQHQAGQAPHLGSGQPQQNLYHPGALT--GTPPSLPPGPSAQSPQSSFPQPAAVYA 947 AP+ + G AP P T GT P+ P+ +P+ P+ A Sbjct: 616 APTTPK---GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 672 Query: 948 IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPP 986 + P T+ +T T P P P P Sbjct: 673 ---TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP 708 Score = 62.8 bits (151), Expect = 2e-09 Identities = 107/502 (21%), Positives = 162/502 (32%), Gaps = 67/502 (13%) Query: 406 SRMSPKAQRPLRGAKTLSSPSN--RPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCP 463 ++ +P + T S+P+ PS T+ P P + P +PK AP P Sbjct: 393 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 452 Query: 464 EPPIGSAVPTSSASIPVTSSVSDPGV-GSISPASPKISLAPTDVKEL--STKEPGRTLEP 520 P A T+ P T P +P +PK L PT ++L +T E P Sbjct: 453 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTP 511 Query: 521 QELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFP-------PRILK 573 +ELA + P ++ +++P +P P P K Sbjct: 512 EELAPTTPEEPTPTTPEEPAP-----------TTPKAAAPNTPKEPAPTTPKEPAPTTPK 560 Query: 574 EEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG 633 E KE + P G+ ++ E KP T E C Sbjct: 561 EPAPTTPKET---APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 617 Query: 634 SPPVGLIKGEDKDEGPV-----AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPR 688 + P G K+ P A K T KE PT P K + T+ GP Sbjct: 618 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP- 676 Query: 689 THSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAK 748 T +T P T + P PA P+ P P + P Sbjct: 677 TSTTSDKPAPTTPK---------ETAPTTPKEPAPTTPKK-PAPTTPETP---------- 716 Query: 749 GSLPPQRSDQHQPASA--PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMA 806 PP S+ P + P + + P ++A P + +P++ PG P P A Sbjct: 717 ---PPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE-PGVPTTKTPAA 772 Query: 807 HYPSQPVFAP------MLQSNPRMLTSGSHPQAIVSSSTPQYPSAE--QPTPQALYATVH 858 P A L++ P T+ +++T + ++ T Q T Sbjct: 773 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 832 Query: 859 QSYPHHATQLHAHQPQPATTPT 880 + P T L P T T Sbjct: 833 DTTPFKITTLKTTTLAPKVTTT 854 Score = 61.2 bits (147), Expect = 5e-09 Identities = 113/544 (20%), Positives = 176/544 (32%), Gaps = 67/544 (12%) Query: 381 PRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA 440 P+ P P P + P +P + P +P+ + P PA Sbjct: 306 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 365 Query: 441 VGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKIS 500 P + P+P + P PT++ S P T+ P +P +PK Sbjct: 366 PTTPKEPAPTTTKEPSPTTPKEP-------APTTTKSAPTTTKEPAPTTTKSAPTTPK-E 417 Query: 501 LAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPS 557 +PT KE + KEP T P++ A K P ++ + K Sbjct: 418 PSPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 476 Query: 558 SSPENSLDPFPPRILKEEPK---GKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAP 614 ++P+ + P ++ P+ E T E + + + +E P Sbjct: 477 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 536 Query: 615 SGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGP--VAEQVKKSTLNPNAKEFNPTKPL 672 + P++P P P + P E P A K T KE PT P Sbjct: 537 AAAPNTPKEPAPTTPKE----PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 592 Query: 673 LSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP 732 K + T+ P T +T P P G A P+ P P Sbjct: 593 KPAPKELAPTTTKEP-TSTTCDKPA-----------------PTTPKGTAPTTPK-EPAP 633 Query: 733 VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLV---AATPYSSYIP 789 + P KG+ P + +PA P A P +T P Sbjct: 634 TTPKEPAP----TTPKGTAP---TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 686 Query: 790 YNPQQ----FPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSS---STPQY 842 P++ P +PA P P+ P P S T+ P I S STP+ Sbjct: 687 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 746 Query: 843 PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTG--------SQPQSQHAAPSPV 894 + +PTP+AL + + A +P+ TT + P++ AAP Sbjct: 747 --SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 804 Query: 895 QHQA 898 + A Sbjct: 805 KETA 808 Score = 45.1 bits (105), Expect = 4e-04 Identities = 73/315 (23%), Positives = 110/315 (34%), Gaps = 59/315 (18%) Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464 P+ +PK P A T + P+ TS P P + P +PK AP P Sbjct: 655 PAPTTPKKPAPKELAPTTTKG---PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 711 Query: 465 PPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPT-DVKELSTKEPGRTLEPQEL 523 P TS S P T+ S ++P++S PT E S KEPG P Sbjct: 712 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG---VPTTK 768 Query: 524 ARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEV 583 A K + + +LR ++PE + P++ KE EK Sbjct: 769 TPAATKPEMTTTAKDKTTERDLR-----------TTPETT--TAAPKMTKETATTTEKTT 815 Query: 584 DGLLTSEPMGSPVSSKTESVSDKEDKP---------PLAPSGGT-----------EGPEQ 623 + +T+ +++ S + ++ P LAP T PE+ Sbjct: 816 ESKITA------TTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEE 869 Query: 624 PPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP- 682 P T S K P ++ K+ P + + T P + K+T TP Sbjct: 870 TAKPKDRATNS----------KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPR 919 Query: 683 --TSPGPRTHSTPSI 695 TS P + T I Sbjct: 920 KMTSTMPELNPTSRI 934 Score = 40.8 bits (94), Expect = 0.007 Identities = 102/472 (21%), Positives = 144/472 (30%), Gaps = 60/472 (12%) Query: 589 SEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEG 648 S P S S +T +KE + T + + + K KD Sbjct: 129 SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 188 Query: 649 PVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSP 708 P ++ + K T P A E P L+ K TPT+P +TP P +P Sbjct: 189 PTSKVLAKPT--PKA-ETTTKGPALTTPKEP-TPTTPKEPASTTPKEP----------TP 234 Query: 709 QYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMM 768 I P PA + P + P + P + +PA P Sbjct: 235 TTIKSAPTTPKEPAPTTTKSAP-----TTPKE------------PAPTTTKEPAPTTPKE 277 Query: 769 QAAAAAGPPLVAATPYSSYIPYNP-QQFPGQPAMMQPMAHYPSQPVF-APMLQSNPRMLT 826 A P T + P P P +PA P P+ P P P T Sbjct: 278 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 337 Query: 827 SGSHPQAIVSSSTPQYPSAEQP------TPQALYATVHQSYPHHATQLHAHQPQPATTPT 880 P +TP+ P+ P TP+ T P +P P TTP Sbjct: 338 KEPAP------TTPKEPAPTAPKKPAPTTPKEPAPTT----PKEPAPTTTKEPSP-TTPK 386 Query: 881 GSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFP 940 P + +AP+ + A P++ P P+ P P+ +P+ P Sbjct: 387 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP--SPTTTKEPAPTTPKEPAPTTPKKPAP 444 Query: 941 QPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGP 1000 A + P T + T P AP P+ + P+ P Sbjct: 445 TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTT---PKETAPTTPKKLTPTTPEKL-AP 500 Query: 1001 PQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRIPPLPPP 1052 P P A T P P E+P AP P A P P P Sbjct: 501 TTPEKPAPTTPEELAPTTPEEPTPTTP--EEP--APTTPKAAAPNTPKEPAP 548 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 70.9 bits (172), Expect = 6e-12 Identities = 128/566 (22%), Positives = 197/566 (34%), Gaps = 71/566 (12%) Query: 394 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRP------SGETSVPPPPAVGRMYPP 447 P +A GP+ +PK P + S+ P S T+ P P Sbjct: 238 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 297 Query: 448 RSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVK 507 +PK AP P P A T+ P T+ + +P +PK APT Sbjct: 298 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPT--- 353 Query: 508 ELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPF 567 + KEP T P+E K P ++ + A K P++ E + Sbjct: 354 --TPKEPAPT-TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA---- 406 Query: 568 PPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP 627 P KE KE EP +P ++K+ + KE AP+ P P P Sbjct: 407 -PTTPKEPAPTTTKEPSPTTPKEP--APTTTKSAPTTTKEP----APTTTKSAPTTPKEP 459 Query: 628 CPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNK--STSTPTSP 685 P+ T P K+ P + T P +P + K + +TP P Sbjct: 460 SPTTTKEP----APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 515 Query: 686 GPRT--HSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK 743 P T + P+ P +P+ ++ P PA P+ ++ + P + Sbjct: 516 APTTPKETAPTTPKKLTPT----TPEKLA--PTTPEKPAPTTPE----ELAPTTPEE--- 562 Query: 744 YRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQ 803 P + +PA P +AAA P A T P P+ +PA Sbjct: 563 ---------PTPTTPEEPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPK----EPAPTT 607 Query: 804 PMAHYPSQPV-FAPMLQSNPRMLT-SGSHPQAIVSSST--PQYPSAEQPTPQALYATVHQ 859 P P+ P AP P T P+ + ++T P + ++P P T Sbjct: 608 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA-P 666 Query: 860 SYPHHATQLHAHQPQPATTPTGSQPQS-QHAAPSPVQHQAGQ--APHLGSGQPQQNLYHP 916 + P +P P TTP G+ P + + AP+ + A + AP G P Sbjct: 667 TTPKEPAPTTPKEPAP-TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 725 Query: 917 GALT--GTPPSLPPGPSAQSPQSSFP 940 T T P+ P P+ +P+ P Sbjct: 726 APTTPKETAPTTPKEPAPTTPKKPAP 751 Score = 67.8 bits (164), Expect = 5e-11 Identities = 124/579 (21%), Positives = 183/579 (31%), Gaps = 72/579 (12%) Query: 419 AKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASI 478 +K L+ P+ P ET+ P + P+ P P +++ P+ P PT+ S Sbjct: 232 SKVLAKPT--PKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEP----TPTTIKSA 281 Query: 479 PVTSSVSDPGVGSISPASPKISLAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQN 535 P T PA APT KE +TKEP T P+E A K P Sbjct: 282 PTTPK---------EPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKEPA--- 328 Query: 536 EQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSP 595 S+P +P P K P KE EP +P Sbjct: 329 -----------------PTTTKSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEP--TP 368 Query: 596 VSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG-SPPVGLIKGEDKDEGPVAEQV 654 + K + + KE P P++P P P + + P K+ P + Sbjct: 369 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 428 Query: 655 KKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYI 714 T +A + + +TP P P T P+ T + +P+ Sbjct: 429 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTTPK--KPA 484 Query: 715 PQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAA 774 P PA P+ P P + P A + P + + P + A Sbjct: 485 PTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTPEKLAPT 542 Query: 775 GPPLVAATPYSSYIPYNPQQ----FPGQPAMMQPMAHYPSQPVF-APMLQSNPRMLTSGS 829 P A T P P++ P +PA P A P+ P AP P T Sbjct: 543 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 602 Query: 830 HPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHA 889 + P P PT T+ + P + + P TT + Sbjct: 603 PAPTTPKETAPTTPKGTAPT------TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 656 Query: 890 APSPVQHQAGQAPHLGSGQPQQNLYHPGALT--GTPPSLPPGPSAQSPQSSFPQPAAVYA 947 AP+ + G AP P T GT P+ P+ +P+ P+ A Sbjct: 657 APTTPK---GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 713 Query: 948 IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPP 986 + P T+ +T T P P P P Sbjct: 714 ---TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP 749 Score = 62.8 bits (151), Expect = 2e-09 Identities = 107/502 (21%), Positives = 162/502 (32%), Gaps = 67/502 (13%) Query: 406 SRMSPKAQRPLRGAKTLSSPSN--RPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCP 463 ++ +P + T S+P+ PS T+ P P + P +PK AP P Sbjct: 434 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 493 Query: 464 EPPIGSAVPTSSASIPVTSSVSDPGV-GSISPASPKISLAPTDVKEL--STKEPGRTLEP 520 P A T+ P T P +P +PK L PT ++L +T E P Sbjct: 494 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTP 552 Query: 521 QELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFP-------PRILK 573 +ELA + P ++ +++P +P P P K Sbjct: 553 EELAPTTPEEPTPTTPEEPAP-----------TTPKAAAPNTPKEPAPTTPKEPAPTTPK 601 Query: 574 EEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG 633 E KE + P G+ ++ E KP T E C Sbjct: 602 EPAPTTPKET---APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 658 Query: 634 SPPVGLIKGEDKDEGPV-----AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPR 688 + P G K+ P A K T KE PT P K + T+ GP Sbjct: 659 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP- 717 Query: 689 THSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAK 748 T +T P T + P PA P+ P P + P Sbjct: 718 TSTTSDKPAPTTPK---------ETAPTTPKEPAPTTPKK-PAPTTPETP---------- 757 Query: 749 GSLPPQRSDQHQPASA--PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMA 806 PP S+ P + P + + P ++A P + +P++ PG P P A Sbjct: 758 ---PPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE-PGVPTTKTPAA 813 Query: 807 HYPSQPVFAP------MLQSNPRMLTSGSHPQAIVSSSTPQYPSAE--QPTPQALYATVH 858 P A L++ P T+ +++T + ++ T Q T Sbjct: 814 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 873 Query: 859 QSYPHHATQLHAHQPQPATTPT 880 + P T L P T T Sbjct: 874 DTTPFKITTLKTTTLAPKVTTT 895 Score = 61.2 bits (147), Expect = 5e-09 Identities = 113/544 (20%), Positives = 176/544 (32%), Gaps = 67/544 (12%) Query: 381 PRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA 440 P+ P P P + P +P + P +P+ + P PA Sbjct: 347 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 406 Query: 441 VGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKIS 500 P + P+P + P PT++ S P T+ P +P +PK Sbjct: 407 PTTPKEPAPTTTKEPSPTTPKEP-------APTTTKSAPTTTKEPAPTTTKSAPTTPK-E 458 Query: 501 LAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPS 557 +PT KE + KEP T P++ A K P ++ + K Sbjct: 459 PSPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 517 Query: 558 SSPENSLDPFPPRILKEEPK---GKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAP 614 ++P+ + P ++ P+ E T E + + + +E P Sbjct: 518 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 577 Query: 615 SGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGP--VAEQVKKSTLNPNAKEFNPTKPL 672 + P++P P P + P E P A K T KE PT P Sbjct: 578 AAAPNTPKEPAPTTPKE----PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 633 Query: 673 LSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP 732 K + T+ P T +T P P G A P+ P P Sbjct: 634 KPAPKELAPTTTKEP-TSTTCDKPA-----------------PTTPKGTAPTTPK-EPAP 674 Query: 733 VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLV---AATPYSSYIP 789 + P KG+ P + +PA P A P +T P Sbjct: 675 TTPKEPAP----TTPKGTAP---TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 727 Query: 790 YNPQQ----FPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSS---STPQY 842 P++ P +PA P P+ P P S T+ P I S STP+ Sbjct: 728 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 787 Query: 843 PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTG--------SQPQSQHAAPSPV 894 + +PTP+AL + + A +P+ TT + P++ AAP Sbjct: 788 --SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 845 Query: 895 QHQA 898 + A Sbjct: 846 KETA 849 Score = 45.1 bits (105), Expect = 4e-04 Identities = 73/315 (23%), Positives = 110/315 (34%), Gaps = 59/315 (18%) Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464 P+ +PK P A T + P+ TS P P + P +PK AP P Sbjct: 696 PAPTTPKKPAPKELAPTTTKG---PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 752 Query: 465 PPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPT-DVKELSTKEPGRTLEPQEL 523 P TS S P T+ S ++P++S PT E S KEPG P Sbjct: 753 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG---VPTTK 809 Query: 524 ARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEV 583 A K + + +LR ++PE + P++ KE EK Sbjct: 810 TPAATKPEMTTTAKDKTTERDLR-----------TTPETT--TAAPKMTKETATTTEKTT 856 Query: 584 DGLLTSEPMGSPVSSKTESVSDKEDKP---------PLAPSGGT-----------EGPEQ 623 + +T+ +++ S + ++ P LAP T PE+ Sbjct: 857 ESKITA------TTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEE 910 Query: 624 PPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP- 682 P T S K P ++ K+ P + + T P + K+T TP Sbjct: 911 TAKPKDRATNS----------KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPR 960 Query: 683 --TSPGPRTHSTPSI 695 TS P + T I Sbjct: 961 KMTSTMPELNPTSRI 975 Score = 40.8 bits (94), Expect = 0.007 Identities = 102/472 (21%), Positives = 144/472 (30%), Gaps = 60/472 (12%) Query: 589 SEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEG 648 S P S S +T +KE + T + + + K KD Sbjct: 170 SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 229 Query: 649 PVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSP 708 P ++ + K T P A E P L+ K TPT+P +TP P +P Sbjct: 230 PTSKVLAKPT--PKA-ETTTKGPALTTPKEP-TPTTPKEPASTTPKEP----------TP 275 Query: 709 QYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMM 768 I P PA + P + P + P + +PA P Sbjct: 276 TTIKSAPTTPKEPAPTTTKSAP-----TTPKE------------PAPTTTKEPAPTTPKE 318 Query: 769 QAAAAAGPPLVAATPYSSYIPYNP-QQFPGQPAMMQPMAHYPSQPVF-APMLQSNPRMLT 826 A P T + P P P +PA P P+ P P P T Sbjct: 319 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 378 Query: 827 SGSHPQAIVSSSTPQYPSAEQP------TPQALYATVHQSYPHHATQLHAHQPQPATTPT 880 P +TP+ P+ P TP+ T P +P P TTP Sbjct: 379 KEPAP------TTPKEPAPTAPKKPAPTTPKEPAPTT----PKEPAPTTTKEPSP-TTPK 427 Query: 881 GSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFP 940 P + +AP+ + A P++ P P+ P P+ +P+ P Sbjct: 428 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP--SPTTTKEPAPTTPKEPAPTTPKKPAP 485 Query: 941 QPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGP 1000 A + P T + T P AP P+ + P+ P Sbjct: 486 TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTT---PKETAPTTPKKLTPTTPEKL-AP 541 Query: 1001 PQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRIPPLPPP 1052 P P A T P P E+P AP P A P P P Sbjct: 542 TTPEKPAPTTPEELAPTTPEEPTPTTP--EEP--APTTPKAAAPNTPKEPAP 589 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 70.9 bits (172), Expect = 6e-12 Identities = 128/566 (22%), Positives = 197/566 (34%), Gaps = 71/566 (12%) Query: 394 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRP------SGETSVPPPPAVGRMYPP 447 P +A GP+ +PK P + S+ P S T+ P P Sbjct: 290 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 349 Query: 448 RSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVK 507 +PK AP P P A T+ P T+ + +P +PK APT Sbjct: 350 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPT--- 405 Query: 508 ELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPF 567 + KEP T P+E K P ++ + A K P++ E + Sbjct: 406 --TPKEPAPT-TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA---- 458 Query: 568 PPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP 627 P KE KE EP +P ++K+ + KE AP+ P P P Sbjct: 459 -PTTPKEPAPTTTKEPSPTTPKEP--APTTTKSAPTTTKEP----APTTTKSAPTTPKEP 511 Query: 628 CPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNK--STSTPTSP 685 P+ T P K+ P + T P +P + K + +TP P Sbjct: 512 SPTTTKEP----APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 567 Query: 686 GPRT--HSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK 743 P T + P+ P +P+ ++ P PA P+ ++ + P + Sbjct: 568 APTTPKETAPTTPKKLTPT----TPEKLA--PTTPEKPAPTTPE----ELAPTTPEE--- 614 Query: 744 YRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQ 803 P + +PA P +AAA P A T P P+ +PA Sbjct: 615 ---------PTPTTPEEPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPK----EPAPTT 659 Query: 804 PMAHYPSQPV-FAPMLQSNPRMLT-SGSHPQAIVSSST--PQYPSAEQPTPQALYATVHQ 859 P P+ P AP P T P+ + ++T P + ++P P T Sbjct: 660 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA-P 718 Query: 860 SYPHHATQLHAHQPQPATTPTGSQPQS-QHAAPSPVQHQAGQ--APHLGSGQPQQNLYHP 916 + P +P P TTP G+ P + + AP+ + A + AP G P Sbjct: 719 TTPKEPAPTTPKEPAP-TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 777 Query: 917 GALT--GTPPSLPPGPSAQSPQSSFP 940 T T P+ P P+ +P+ P Sbjct: 778 APTTPKETAPTTPKEPAPTTPKKPAP 803 Score = 67.8 bits (164), Expect = 5e-11 Identities = 124/579 (21%), Positives = 183/579 (31%), Gaps = 72/579 (12%) Query: 419 AKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASI 478 +K L+ P+ P ET+ P + P+ P P +++ P+ P PT+ S Sbjct: 284 SKVLAKPT--PKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEP----TPTTIKSA 333 Query: 479 PVTSSVSDPGVGSISPASPKISLAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQN 535 P T PA APT KE +TKEP T P+E A K P Sbjct: 334 PTTPK---------EPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKEPA--- 380 Query: 536 EQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSP 595 S+P +P P K P KE EP +P Sbjct: 381 -----------------PTTTKSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEP--TP 420 Query: 596 VSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG-SPPVGLIKGEDKDEGPVAEQV 654 + K + + KE P P++P P P + + P K+ P + Sbjct: 421 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 480 Query: 655 KKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYI 714 T +A + + +TP P P T P+ T + +P+ Sbjct: 481 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTTPK--KPA 536 Query: 715 PQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAA 774 P PA P+ P P + P A + P + + P + A Sbjct: 537 PTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTPEKLAPT 594 Query: 775 GPPLVAATPYSSYIPYNPQQ----FPGQPAMMQPMAHYPSQPVF-APMLQSNPRMLTSGS 829 P A T P P++ P +PA P A P+ P AP P T Sbjct: 595 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 654 Query: 830 HPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHA 889 + P P PT T+ + P + + P TT + Sbjct: 655 PAPTTPKETAPTTPKGTAPT------TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 708 Query: 890 APSPVQHQAGQAPHLGSGQPQQNLYHPGALT--GTPPSLPPGPSAQSPQSSFPQPAAVYA 947 AP+ + G AP P T GT P+ P+ +P+ P+ A Sbjct: 709 APTTPK---GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 765 Query: 948 IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPP 986 + P T+ +T T P P P P Sbjct: 766 ---TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP 801 Score = 62.8 bits (151), Expect = 2e-09 Identities = 107/502 (21%), Positives = 162/502 (32%), Gaps = 67/502 (13%) Query: 406 SRMSPKAQRPLRGAKTLSSPSN--RPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCP 463 ++ +P + T S+P+ PS T+ P P + P +PK AP P Sbjct: 486 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 545 Query: 464 EPPIGSAVPTSSASIPVTSSVSDPGV-GSISPASPKISLAPTDVKEL--STKEPGRTLEP 520 P A T+ P T P +P +PK L PT ++L +T E P Sbjct: 546 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTP 604 Query: 521 QELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFP-------PRILK 573 +ELA + P ++ +++P +P P P K Sbjct: 605 EELAPTTPEEPTPTTPEEPAP-----------TTPKAAAPNTPKEPAPTTPKEPAPTTPK 653 Query: 574 EEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG 633 E KE + P G+ ++ E KP T E C Sbjct: 654 EPAPTTPKET---APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 710 Query: 634 SPPVGLIKGEDKDEGPV-----AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPR 688 + P G K+ P A K T KE PT P K + T+ GP Sbjct: 711 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP- 769 Query: 689 THSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAK 748 T +T P T + P PA P+ P P + P Sbjct: 770 TSTTSDKPAPTTPK---------ETAPTTPKEPAPTTPKK-PAPTTPETP---------- 809 Query: 749 GSLPPQRSDQHQPASA--PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMA 806 PP S+ P + P + + P ++A P + +P++ PG P P A Sbjct: 810 ---PPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE-PGVPTTKTPAA 865 Query: 807 HYPSQPVFAP------MLQSNPRMLTSGSHPQAIVSSSTPQYPSAE--QPTPQALYATVH 858 P A L++ P T+ +++T + ++ T Q T Sbjct: 866 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 925 Query: 859 QSYPHHATQLHAHQPQPATTPT 880 + P T L P T T Sbjct: 926 DTTPFKITTLKTTTLAPKVTTT 947 Score = 61.2 bits (147), Expect = 5e-09 Identities = 113/544 (20%), Positives = 176/544 (32%), Gaps = 67/544 (12%) Query: 381 PRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA 440 P+ P P P + P +P + P +P+ + P PA Sbjct: 399 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 458 Query: 441 VGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKIS 500 P + P+P + P PT++ S P T+ P +P +PK Sbjct: 459 PTTPKEPAPTTTKEPSPTTPKEP-------APTTTKSAPTTTKEPAPTTTKSAPTTPK-E 510 Query: 501 LAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPS 557 +PT KE + KEP T P++ A K P ++ + K Sbjct: 511 PSPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 569 Query: 558 SSPENSLDPFPPRILKEEPK---GKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAP 614 ++P+ + P ++ P+ E T E + + + +E P Sbjct: 570 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 629 Query: 615 SGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGP--VAEQVKKSTLNPNAKEFNPTKPL 672 + P++P P P + P E P A K T KE PT P Sbjct: 630 AAAPNTPKEPAPTTPKE----PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 685 Query: 673 LSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP 732 K + T+ P T +T P P G A P+ P P Sbjct: 686 KPAPKELAPTTTKEP-TSTTCDKPA-----------------PTTPKGTAPTTPK-EPAP 726 Query: 733 VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLV---AATPYSSYIP 789 + P KG+ P + +PA P A P +T P Sbjct: 727 TTPKEPAP----TTPKGTAP---TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 779 Query: 790 YNPQQ----FPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSS---STPQY 842 P++ P +PA P P+ P P S T+ P I S STP+ Sbjct: 780 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 839 Query: 843 PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTG--------SQPQSQHAAPSPV 894 + +PTP+AL + + A +P+ TT + P++ AAP Sbjct: 840 --SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 897 Query: 895 QHQA 898 + A Sbjct: 898 KETA 901 Score = 45.1 bits (105), Expect = 4e-04 Identities = 73/315 (23%), Positives = 110/315 (34%), Gaps = 59/315 (18%) Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464 P+ +PK P A T + P+ TS P P + P +PK AP P Sbjct: 748 PAPTTPKKPAPKELAPTTTKG---PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 804 Query: 465 PPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPT-DVKELSTKEPGRTLEPQEL 523 P TS S P T+ S ++P++S PT E S KEPG P Sbjct: 805 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG---VPTTK 861 Query: 524 ARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEV 583 A K + + +LR ++PE + P++ KE EK Sbjct: 862 TPAATKPEMTTTAKDKTTERDLR-----------TTPETT--TAAPKMTKETATTTEKTT 908 Query: 584 DGLLTSEPMGSPVSSKTESVSDKEDKP---------PLAPSGGT-----------EGPEQ 623 + +T+ +++ S + ++ P LAP T PE+ Sbjct: 909 ESKITA------TTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEE 962 Query: 624 PPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP- 682 P T S K P ++ K+ P + + T P + K+T TP Sbjct: 963 TAKPKDRATNS----------KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPR 1012 Query: 683 --TSPGPRTHSTPSI 695 TS P + T I Sbjct: 1013 KMTSTMPELNPTSRI 1027 Score = 43.9 bits (102), Expect = 8e-04 Identities = 132/636 (20%), Positives = 202/636 (31%), Gaps = 74/636 (11%) Query: 432 ETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGS 491 E P P + PP S S + P+PP S +T S Sbjct: 65 EVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQE 124 Query: 492 ISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGA- 550 S +S S + T K S+K E Q+ ++ ++ + + + G+ Sbjct: 125 SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSG 184 Query: 551 ----QFKLQP--SSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVS 604 FK+ +S+ +++ P+I +P + + S +K +V Sbjct: 185 LDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVE 244 Query: 605 DKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAK 664 KE + T+G E+ +Q+ + K KD P ++ + K T P A Sbjct: 245 TKETTTTNKQTS-TDGKEKTTSAKETQS------IEKTSAKDLAPTSKVLAKPT--PKA- 294 Query: 665 EFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQ 724 E P L+ K TPT+P +TP P +P I P PA Sbjct: 295 ETTTKGPALTTPKEP-TPTTPKEPASTTPKEP----------TPTTIKSAPTTPKEPAPT 343 Query: 725 APQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPY 784 + P + P + P + +PA P A P T Sbjct: 344 TTKSAP-----TTPKE------------PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS 386 Query: 785 SSYIPYNP-QQFPGQPAMMQPMAHYPSQPVF-APMLQSNPRMLTSGSHPQAIVSSSTPQY 842 + P P P +PA P P+ P P P T P +TP+ Sbjct: 387 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP------TTPKE 440 Query: 843 PSAEQP------TPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQH 896 P+ P TP+ T P +P P TTP P + +AP+ + Sbjct: 441 PAPTAPKKPAPTTPKEPAPTT----PKEPAPTTTKEPSP-TTPKEPAPTTTKSAPTTTKE 495 Query: 897 QAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHG 956 A P++ P P+ P P+ +P+ P A + P Sbjct: 496 PAPTTTKSAPTTPKEP--SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 553 Query: 957 FTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSAS 1016 T + T P AP P+ + P+ P P P A Sbjct: 554 TTTKKPAPTTPKEPAPTT---PKETAPTTPKKLTPTTPEKL-APTTPEKPAPTTPEELAP 609 Query: 1017 TPSPYPYIGHPQGEQPGQAPGFPGGADDRIPPLPPP 1052 T P P E+P AP P A P P P Sbjct: 610 TTPEEPTPTTP--EEP--APTTPKAAAPNTPKEPAP 641 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.309 0.129 0.386 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 62,046,888 Number of Sequences: 37866 Number of extensions: 4579583 Number of successful extensions: 52882 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 371 Number of HSP's successfully gapped in prelim test: 2409 Number of HSP's that attempted gapping in prelim test: 22958 Number of HSP's gapped (non-prelim): 22492 length of query: 1062 length of database: 18,247,518 effective HSP length: 113 effective length of query: 949 effective length of database: 13,968,660 effective search space: 13256258340 effective search space used: 13256258340 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.