Guide to the Human Genome
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Search of human proteins with 27262645

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27262645 ataxin 2 related protein isoform B [Homo sapiens]
         (1062 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27262645 ataxin 2 related protein isoform B [Homo sapiens]        2183   0.0  
gi|27262649 ataxin 2 related protein isoform C [Homo sapiens]        2151   0.0  
gi|27262647 ataxin 2 related protein isoform A [Homo sapiens]        2151   0.0  
gi|27262653 ataxin 2 related protein isoform E [Homo sapiens]        2130   0.0  
gi|27262651 ataxin 2 related protein isoform D [Homo sapiens]        2112   0.0  
gi|171543895 ataxin 2 [Homo sapiens]                                  610   e-174
gi|163965366 nascent polypeptide-associated complex alpha subuni...   110   9e-24
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...   104   4e-22
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    98   4e-20
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    97   8e-20
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    92   3e-18
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          87   1e-16
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          87   1e-16
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          85   3e-16
gi|150170670 piccolo isoform 2 [Homo sapiens]                          81   6e-15
gi|150378539 piccolo isoform 1 [Homo sapiens]                          81   6e-15
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     80   1e-14
gi|55750053 atrophin-1 [Homo sapiens]                                  78   4e-14
gi|55750041 atrophin-1 [Homo sapiens]                                  78   4e-14
gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s...    74   6e-13
gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s...    74   6e-13
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]               74   7e-13
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    74   1e-12
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]       73   1e-12
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              72   3e-12
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ...    72   4e-12
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ...    72   4e-12
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   71   6e-12
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   71   6e-12
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   71   6e-12

>gi|27262645 ataxin 2 related protein isoform B [Homo sapiens]
          Length = 1062

 Score = 2183 bits (5657), Expect = 0.0
 Identities = 1062/1062 (100%), Positives = 1062/1062 (100%)

Query: 1    MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
            MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG
Sbjct: 1    MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60

Query: 61   PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
            PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN
Sbjct: 61   PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120

Query: 121  SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180
            SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV
Sbjct: 121  SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180

Query: 181  DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240
            DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD
Sbjct: 181  DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240

Query: 241  YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300
            YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA
Sbjct: 241  YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300

Query: 301  REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360
            REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP
Sbjct: 301  REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360

Query: 361  RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420
            RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK
Sbjct: 361  RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420

Query: 421  TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
            TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV
Sbjct: 421  TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480

Query: 481  TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540
            TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF
Sbjct: 481  TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540

Query: 541  QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600
            QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT
Sbjct: 541  QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600

Query: 601  ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660
            ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN
Sbjct: 601  ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660

Query: 661  PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720
            PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG
Sbjct: 661  PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720

Query: 721  PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780
            PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA
Sbjct: 721  PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780

Query: 781  ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
            ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP
Sbjct: 781  ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840

Query: 841  QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
            QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ
Sbjct: 841  QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900

Query: 901  APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960
            APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM
Sbjct: 901  APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960

Query: 961  AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
            AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP
Sbjct: 961  AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020

Query: 1021 YPYIGHPQGEQPGQAPGFPGGADDRIPPLPPPGELKIVLAAT 1062
            YPYIGHPQGEQPGQAPGFPGGADDRIPPLPPPGELKIVLAAT
Sbjct: 1021 YPYIGHPQGEQPGQAPGFPGGADDRIPPLPPPGELKIVLAAT 1062


>gi|27262649 ataxin 2 related protein isoform C [Homo sapiens]
          Length = 1097

 Score = 2151 bits (5573), Expect = 0.0
 Identities = 1046/1046 (100%), Positives = 1046/1046 (100%)

Query: 1    MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
            MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG
Sbjct: 1    MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60

Query: 61   PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
            PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN
Sbjct: 61   PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120

Query: 121  SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180
            SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV
Sbjct: 121  SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180

Query: 181  DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240
            DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD
Sbjct: 181  DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240

Query: 241  YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300
            YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA
Sbjct: 241  YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300

Query: 301  REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360
            REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP
Sbjct: 301  REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360

Query: 361  RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420
            RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK
Sbjct: 361  RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420

Query: 421  TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
            TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV
Sbjct: 421  TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480

Query: 481  TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540
            TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF
Sbjct: 481  TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540

Query: 541  QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600
            QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT
Sbjct: 541  QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600

Query: 601  ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660
            ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN
Sbjct: 601  ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660

Query: 661  PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720
            PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG
Sbjct: 661  PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720

Query: 721  PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780
            PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA
Sbjct: 721  PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780

Query: 781  ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
            ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP
Sbjct: 781  ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840

Query: 841  QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
            QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ
Sbjct: 841  QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900

Query: 901  APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960
            APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM
Sbjct: 901  APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960

Query: 961  AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
            AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP
Sbjct: 961  AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020

Query: 1021 YPYIGHPQGEQPGQAPGFPGGADDRI 1046
            YPYIGHPQGEQPGQAPGFPGGADDRI
Sbjct: 1021 YPYIGHPQGEQPGQAPGFPGGADDRI 1046



 Score = 38.1 bits (87), Expect = 0.044
 Identities = 24/76 (31%), Positives = 29/76 (38%), Gaps = 2/76 (2%)

Query: 977  PPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAP 1036
            P  P  P P Q  +   P     PP G +P  G  A SA+ P P        G       
Sbjct: 10   PSQPQQPPPTQQAVARRPPGGTSPPNGGLP--GPLATSAAPPGPPAAASPCLGPVAAAGS 67

Query: 1037 GFPGGADDRIPPLPPP 1052
            G   GA+  + P PPP
Sbjct: 68   GLRRGAEGILAPQPPP 83


>gi|27262647 ataxin 2 related protein isoform A [Homo sapiens]
          Length = 1075

 Score = 2151 bits (5573), Expect = 0.0
 Identities = 1046/1046 (100%), Positives = 1046/1046 (100%)

Query: 1    MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
            MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG
Sbjct: 1    MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60

Query: 61   PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
            PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN
Sbjct: 61   PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120

Query: 121  SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180
            SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV
Sbjct: 121  SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180

Query: 181  DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240
            DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD
Sbjct: 181  DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240

Query: 241  YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300
            YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA
Sbjct: 241  YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300

Query: 301  REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360
            REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP
Sbjct: 301  REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360

Query: 361  RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420
            RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK
Sbjct: 361  RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420

Query: 421  TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
            TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV
Sbjct: 421  TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480

Query: 481  TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540
            TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF
Sbjct: 481  TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540

Query: 541  QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600
            QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT
Sbjct: 541  QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600

Query: 601  ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660
            ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN
Sbjct: 601  ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660

Query: 661  PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720
            PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG
Sbjct: 661  PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720

Query: 721  PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780
            PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA
Sbjct: 721  PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780

Query: 781  ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
            ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP
Sbjct: 781  ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840

Query: 841  QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
            QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ
Sbjct: 841  QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900

Query: 901  APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960
            APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM
Sbjct: 901  APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960

Query: 961  AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
            AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP
Sbjct: 961  AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020

Query: 1021 YPYIGHPQGEQPGQAPGFPGGADDRI 1046
            YPYIGHPQGEQPGQAPGFPGGADDRI
Sbjct: 1021 YPYIGHPQGEQPGQAPGFPGGADDRI 1046



 Score = 38.1 bits (87), Expect = 0.044
 Identities = 24/76 (31%), Positives = 29/76 (38%), Gaps = 2/76 (2%)

Query: 977  PPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAP 1036
            P  P  P P Q  +   P     PP G +P  G  A SA+ P P        G       
Sbjct: 10   PSQPQQPPPTQQAVARRPPGGTSPPNGGLP--GPLATSAAPPGPPAAASPCLGPVAAAGS 67

Query: 1037 GFPGGADDRIPPLPPP 1052
            G   GA+  + P PPP
Sbjct: 68   GLRRGAEGILAPQPPP 83


>gi|27262653 ataxin 2 related protein isoform E [Homo sapiens]
          Length = 1044

 Score = 2130 bits (5520), Expect = 0.0
 Identities = 1043/1062 (98%), Positives = 1043/1062 (98%), Gaps = 18/1062 (1%)

Query: 1    MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
            MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG
Sbjct: 1    MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60

Query: 61   PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
            PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN
Sbjct: 61   PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120

Query: 121  SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180
            SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV
Sbjct: 121  SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180

Query: 181  DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240
            DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD
Sbjct: 181  DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240

Query: 241  YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300
            YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA
Sbjct: 241  YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300

Query: 301  REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360
            REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP
Sbjct: 301  REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360

Query: 361  RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420
            RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK
Sbjct: 361  RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420

Query: 421  TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
            TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV
Sbjct: 421  TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480

Query: 481  TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540
            TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF
Sbjct: 481  TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540

Query: 541  QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600
            QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT
Sbjct: 541  QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600

Query: 601  ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660
            ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN
Sbjct: 601  ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660

Query: 661  PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720
            PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG
Sbjct: 661  PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720

Query: 721  PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780
            PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA
Sbjct: 721  PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780

Query: 781  ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
            ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP
Sbjct: 781  ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840

Query: 841  QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
            QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ
Sbjct: 841  QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900

Query: 901  APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960
            APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM
Sbjct: 901  APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960

Query: 961  AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
            AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP
Sbjct: 961  AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020

Query: 1021 YPYIGHPQGEQPGQAPGFPGGADDRIPPLPPPGELKIVLAAT 1062
            YPYIGHPQ                   PLPPPGELKIVLAAT
Sbjct: 1021 YPYIGHPQA------------------PLPPPGELKIVLAAT 1044


>gi|27262651 ataxin 2 related protein isoform D [Homo sapiens]
          Length = 1044

 Score = 2112 bits (5473), Expect = 0.0
 Identities = 1032/1043 (98%), Positives = 1032/1043 (98%), Gaps = 2/1043 (0%)

Query: 1    MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
            MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG
Sbjct: 1    MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60

Query: 61   PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
            PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN
Sbjct: 61   PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120

Query: 121  SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180
            SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV
Sbjct: 121  SRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRREDIV 180

Query: 181  DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240
            DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD
Sbjct: 181  DTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDD 240

Query: 241  YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300
            YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA
Sbjct: 241  YDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLA 300

Query: 301  REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360
            REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP
Sbjct: 301  REIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGP 360

Query: 361  RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420
            RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK
Sbjct: 361  RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAK 420

Query: 421  TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480
            TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV
Sbjct: 421  TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPV 480

Query: 481  TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540
            TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF
Sbjct: 481  TSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRF 540

Query: 541  QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600
            QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT
Sbjct: 541  QLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKT 600

Query: 601  ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660
            ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN
Sbjct: 601  ESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN 660

Query: 661  PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720
            PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG
Sbjct: 661  PNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMG 720

Query: 721  PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780
            PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA
Sbjct: 721  PAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVA 780

Query: 781  ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
            ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP
Sbjct: 781  ATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840

Query: 841  QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
            QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ
Sbjct: 841  QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900

Query: 901  APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960
            APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM
Sbjct: 901  APHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNM 960

Query: 961  AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020
            AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP
Sbjct: 961  AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSP 1020

Query: 1021 YPYIGHP--QGEQPGQAPGFPGG 1041
            YPYIGHP  Q     Q P  P G
Sbjct: 1021 YPYIGHPQVQSHPSQQLPFHPPG 1043



 Score = 38.1 bits (87), Expect = 0.044
 Identities = 24/76 (31%), Positives = 29/76 (38%), Gaps = 2/76 (2%)

Query: 977  PPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAP 1036
            P  P  P P Q  +   P     PP G +P  G  A SA+ P P        G       
Sbjct: 10   PSQPQQPPPTQQAVARRPPGGTSPPNGGLP--GPLATSAAPPGPPAAASPCLGPVAAAGS 67

Query: 1037 GFPGGADDRIPPLPPP 1052
            G   GA+  + P PPP
Sbjct: 68   GLRRGAEGILAPQPPP 83


>gi|171543895 ataxin 2 [Homo sapiens]
          Length = 1313

 Score =  610 bits (1574), Expect = e-174
 Identities = 455/1196 (38%), Positives = 613/1196 (51%), Gaps = 225/1196 (18%)

Query: 2    LKPQPLQQPSQPQQPPPTQQAVARR--PPGGTSPPNGGLPGPLATSAAPPGPPAAASPCL 59
            LKPQ  QQ  Q QQ    QQ   ++  PP   +    G  G LA+ AA P P  ++S   
Sbjct: 163  LKPQQQQQQQQQQQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPSP--SSSSVS 220

Query: 60   GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPV-FEGVY 118
               A A S +     G   P                 G  RG+++ KG PQS + F+G+Y
Sbjct: 221  SSSATAPSSVVAATSGGGRP-----------------GLGRGRNSNKGLPQSTISFDGIY 263

Query: 119  NNSRMLHFLTAVVGSTCDVKVKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRRED 178
             N RM+H LT+VVGS C+V+VKNG  YEG+FKT S K +L +DA H K++E + GP+RE+
Sbjct: 264  ANMRMVHILTSVVGSKCEVQVKNGGIYEGVFKTYSPKCDLVLDAAHEKSTESSSGPKREE 323

Query: 179  IVDTMVFKPSDVMLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGD--S 236
            I+++++FK SD ++V F+++D +YA +D FTDSAI+  +KVNGEHKEK L+ W+ G+  +
Sbjct: 324  IMESILFKCSDFVVVQFKDMDSSYAKRDAFTDSAIS--AKVNGEHKEKDLEPWDAGELTA 381

Query: 237  NSDDYDLESDMSNGWDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRA 296
            N +   LE+D+SNGWDPN+MF++NEENYGV +TYDSSLSSYTVPLE+DNSEEF +RE RA
Sbjct: 382  NEELEALENDVSNGWDPNDMFRYNEENYGVVSTYDSSLSSYTVPLERDNSEEFLKREARA 441

Query: 297  AQLAREIESSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRV 356
             QLA EIESS QY+ R+A+ENDD R+EEEK++AVQR  S RE  S+ +RE KYIP  QR 
Sbjct: 442  NQLAEEIESSAQYKARVALENDD-RSEEEKYTAVQRNSSEREGHSINTRENKYIPPGQRN 500

Query: 357  REG-PRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGG---PSRM-SPK 411
            RE    G  R +S R G+PG  S+P R   H  + +P  GS+ R +NGG   PS   SP 
Sbjct: 501  REVISWGSGRQNSPRMGQPGSGSMPSRSTSHTSDFNPNSGSDQRVVNGGVPWPSPCPSPS 560

Query: 412  AQRPLR----------GAKTLSSPSNRPSGETSVPP---------------PPAVGRMYP 446
            ++ P R           A T + P +RP    S PP               P  +    P
Sbjct: 561  SRPPSRYQSGPNSLPPRAATPTRPPSRPPSRPSRPPSHPSAHGSPAPVSTMPKRMSSEGP 620

Query: 447  PR-SPK----------SAAPAPISASCP----EPPIGSAVPTSSASIPVTSSVSD--PGV 489
            PR SPK          SA    IS+        PP  +A P  + + P   + S    GV
Sbjct: 621  PRMSPKAQRHPRNHRVSAGRGSISSGLEFVSHNPPSEAATPPVARTSPSGGTWSSVVSGV 680

Query: 490  GSISP----------------------ASPKISLAPTDVKELSTKEPGRTLEPQELARIA 527
              +SP                      ASP+  + PT+   ++   P  +  P   A   
Sbjct: 681  PRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGIIPTEA--VAMPIPAASPTPASPASNR 738

Query: 528  GKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN-SLDPFPPRILKEEPKG-------K 579
               P  + +  R Q         Q +  P+ + EN   +   P   K E KG        
Sbjct: 739  AVTPSSEAKDSRLQ--------DQRQNSPAGNKENIKPNETSPSFSKAENKGISPVVSEH 790

Query: 580  EKEVDGL------------LTSEPMGSPVSSKTE-------------------------- 601
             K++D L             TSE M   ++   E                          
Sbjct: 791  RKQIDDLKKFKNDFRLQPSSTSESMDQLLNKNREGEKSRDLIKDKIEPSAKDSFIENSSS 850

Query: 602  ---SVSDKEDKPPLAPSGGTEGPEQPPPPCPS---QTGSPPVGLIKGEDKDEGPVAEQVK 655
               S S K + P ++PS  +    +  P   S   QT SP     K + +++   AEQV+
Sbjct: 851  NCTSGSSKPNSPSISPSILSNTEHKRGPEVTSQGVQTSSPACKQEKDDKEEKKDAAEQVR 910

Query: 656  KSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSI-----PVLTAGQSGLYSPQY 710
            KSTLNPNAKEFNP     S  K ++TPTSP P+   +PS+     P     Q   ++P  
Sbjct: 911  KSTLNPNAKEFNPRS--FSQPKPSTTPTSPRPQAQPSPSMVGHQQPTPVYTQPVCFAPNM 968

Query: 711  ISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQA 770
            +  +P   + P VQ   +YP P++  +P  Q K   A  ++P QR DQH  ++   MM  
Sbjct: 969  MYPVP---VSPGVQ--PLYPIPMT-PMPVNQAKTYRAVPNMPQQRQDQHHQSA---MMHP 1019

Query: 771  AAAAGPPLVAATP-YSS-YIPYNPQQFPGQPAMMQPMAHYPSQ--PVFAPMLQSNPRMLT 826
            A+AAGPP+ A  P YS+ Y+ Y+PQQFP QP ++Q + HY SQ   V++P++Q N RM+ 
Sbjct: 1020 ASAAGPPIAATPPAYSTQYVAYSPQQFPNQP-LVQHVPHYQSQHPHVYSPVIQGNARMMA 1078

Query: 827  SGSHPQ-AIVSSSTPQYPSAEQPTPQALYA---------------------TVHQSYPHH 864
              +H Q  +VSSS  QY + EQ    A+YA                     ++ Q Y H 
Sbjct: 1079 PPTHAQPGLVSSSATQYGAHEQ--THAMYACPKLPYNKETSPSFYFAISTGSLAQQYAHP 1136

Query: 865  ATQLHAH--QPQPATTPTGSQPQSQHA----APSPV---QHQAGQAPHLGSGQPQQNLYH 915
               LH H   PQP+ TPTG Q QSQH     APSPV   QHQA QA HL S Q Q  +YH
Sbjct: 1137 NATLHPHTPHPQPSATPTGQQ-QSQHGGSHPAPSPVQHHQHQAAQALHLASPQQQSAIYH 1195

Query: 916  PGALTGTPPSLPPGPSAQSPQSSFP-QPAAVYAIHHQQLPHGFTN---MAHVTQAHVQTG 971
             G L  TPPS+ P  + QSPQ+SFP     V+ IH   +   +TN   MAHV QAHVQ+G
Sbjct: 1196 AG-LAPTPPSMTPASNTQSPQNSFPAAQQTVFTIHPSHVQPAYTNPPHMAHVPQAHVQSG 1254

Query: 972  ITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHP 1027
            +    P HP A  P  +M   PP    G PQ A+ QS +  +  ST + +PY+ HP
Sbjct: 1255 MV---PSHPTAHAPMMLMTTQPP----GGPQAALAQSALQPIPVSTTAHFPYMTHP 1303



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 37/134 (27%), Positives = 52/134 (38%), Gaps = 10/134 (7%)

Query: 362 GGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKT 421
           G    + +R    G  + PPR    L   +PG    A     GP  MS K Q+  +  + 
Sbjct: 115 GAPPAAPTRASPLGARASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKPQQQQQQQQQ 174

Query: 422 LSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIP-- 479
                 +   +   PPP A     P  S   A+PA   +     P  S+V +SSA+ P  
Sbjct: 175 QQQQQQQQQQQQQQPPPAAANVRKPGGSGLLASPAAAPS-----PSSSSVSSSSATAPSS 229

Query: 480 ---VTSSVSDPGVG 490
               TS    PG+G
Sbjct: 230 VVAATSGGGRPGLG 243



 Score = 35.4 bits (80), Expect = 0.29
 Identities = 45/155 (29%), Positives = 57/155 (36%), Gaps = 14/155 (9%)

Query: 343 ASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPR-GPHHLDNSSPGPGSEARGI 401
           A+R   +  L +  R   RGG    ++ G  P  +  PP  GP     SSP   S+  G 
Sbjct: 22  AARWPGWRSLQRPARRSGRGGG--GAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGS 79

Query: 402 NGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVP--PPPAVGRMYPPRSPKSAAPAPIS 459
           NG          R L G   L  P  RP     +P   P A     PP +P  A+P    
Sbjct: 80  NGNGGGAFRPGSRRLLG---LGGPP-RPFVVLLLPLASPGA-----PPAAPTRASPLGAR 130

Query: 460 ASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISP 494
           AS P   +  A P      P    V  P   S+ P
Sbjct: 131 ASPPRSGVSLARPAPGCPRPACEPVYGPLTMSLKP 165



 Score = 33.9 bits (76), Expect = 0.84
 Identities = 34/110 (30%), Positives = 40/110 (36%), Gaps = 20/110 (18%)

Query: 21  QAVARRPPGGTSPPNGGLPGPLATSA-APPGP---------PAAASPCLGPVAAAGSGLR 70
           Q  ARR   G     G  PGP  ++A  PPGP         P +AS C G     G   R
Sbjct: 32  QRPARRSGRGGG---GAAPGPYPSAAPPPPGPGPPPSRQSSPPSASDCFGSNGNGGGAFR 88

Query: 71  RGAEGILAPQPPPPQ-----QHQERPGAAAIGSARGQSTG--KGPPQSPV 113
            G+  +L    PP            PGA      R    G    PP+S V
Sbjct: 89  PGSRRLLGLGGPPRPFVVLLLPLASPGAPPAAPTRASPLGARASPPRSGV 138


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score =  110 bits (274), Expect = 9e-24
 Identities = 181/763 (23%), Positives = 254/763 (33%), Gaps = 119/763 (15%)

Query: 345  REGKYIPLPQRVREGPRGGVRCSSSRGGR--PGLSSLPPRGPHHLDNSSPGPGSEARGIN 402
            +EG   P P   ++ P   +  SS +  R  P    +P   P      +P P +      
Sbjct: 897  KEGPATPAP---KQAPALSMTSSSPKKARATPAPKGIPA-SPSPKGAPTP-PAATPPSPK 951

Query: 403  GGPSRMSPK-------AQRPL-RGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAA 454
            GGP+  SPK       A  P  +G     SP   P+   + PP P  G   P  SPK  A
Sbjct: 952  GGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATP--SPK-GA 1008

Query: 455  PAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEP 514
            P P + + P P        S A+ P     S P   + +P SPK S A T + + +   P
Sbjct: 1009 PTPPAVTPPSP------KGSPAATPFPKGASTP--PAATPPSPKGSPAATPLPKGAPTTP 1060

Query: 515  GRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLD---PFPPRI 571
              TL   +       + G                 A     P   P        P PP  
Sbjct: 1061 AATLPSPKGGPATPSLKGAPTPP------------AATPPSPKGGPATPSPKGAPMPPAA 1108

Query: 572  LKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQ 631
                PKG      GL T    G+P +      S K       P G    P   PP     
Sbjct: 1109 TPPSPKG------GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGG 1162

Query: 632  TGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHS 691
              +PP    KG            K     P+ K   PT P  +         +P P+   
Sbjct: 1163 LATPPP---KGAPTTPAATPPSPKGGLATPSPKG-APTTPAATPPSPKGGLATPSPKGAP 1218

Query: 692  TPSIPVLTAGQSGLYSPQ-------YISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKY 744
            T       + + GL +P          +  P    GPA   P+  P P + + P  +G  
Sbjct: 1219 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGL 1278

Query: 745  RGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQP 804
                 + PP +   +     PP  +   A  PP  A TP ++  P +P+  PG P    P
Sbjct: 1279 -----ATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAA-TPPSPKGSPGTP----P 1328

Query: 805  MAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHH 864
                P+ P   P        L + + P +    +TP   S E PTP A       + P H
Sbjct: 1329 PKGAPTPPAVTPPSPKGTPTLPA-TTPSSKGGPTTPS--SKEGPTPPA-------ATPSH 1378

Query: 865  ATQLHAHQPQPATTPTGSQPQSQHAAP-----SPVQHQAGQAPHLGSGQPQQNLYHPGAL 919
                    P P   P    P+    +P     SP +  A      G+  P +    P A+
Sbjct: 1379 KGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAV 1438

Query: 920  TGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPH 979
              TP SL   P+  +P+     PA   +     LP           A  Q   +++P   
Sbjct: 1439 --TPVSLKKAPATSAPKGG---PATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKA 1493

Query: 980  P------GAPHPPQVMLLHP------PQSHGGP------------PQGAVPQSGV--PAL 1013
            P      GAP  P V+   P      P S   P            P    P+  +  PA+
Sbjct: 1494 PATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAM 1553

Query: 1014 SASTPSPYPYIGHPQGEQPGQAPGFPGGADDRIPPLPPPGELK 1056
            +  +P   P I  P+     +AP  P   +   PP   P   K
Sbjct: 1554 TVPSPKKTPAIPTPK-----EAPATPSSKEASSPPAVTPSTYK 1591



 Score = 99.0 bits (245), Expect = 2e-20
 Identities = 175/749 (23%), Positives = 233/749 (31%), Gaps = 169/749 (22%)

Query: 375  GLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMS----PKAQRPLRGAK----TLSSPS 426
            G+S  P          S GP +    ++   S +     P+     +G+K    T  SP+
Sbjct: 798  GVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPT 857

Query: 427  NRPSGETSVPPPPAVGRMYPP--RSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSV 484
              P      P P AV  + P     P    P P   + P P  G A P    +  ++ + 
Sbjct: 858  --PPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTS 915

Query: 485  SDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEE 544
            S P     +PA   I  +P+  K   T        P+                       
Sbjct: 916  SSPKKARATPAPKGIPASPSP-KGAPTPPAATPPSPK----------------------- 951

Query: 545  LRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVS 604
                         ++P     P PP      PKG      G  T  P G+P        S
Sbjct: 952  ----------GGPATPSPKWAPTPPAATPPSPKG------GPATPSPKGAPTPPAATPPS 995

Query: 605  DKEDKPPLAPSGGTEGPEQPPPPCPSQTGSP-PVGLIKGEDKDEGPVAEQVKKSTLNPNA 663
             K      +P G    P   P   PS  GSP      KG            K S      
Sbjct: 996  PKGGPATPSPKGAPTPPAVTP---PSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPL 1052

Query: 664  KEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAV 723
             +  PT P  ++      P +P  +   TP  P  T               P    GPA 
Sbjct: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAPTP--PAATP--------------PSPKGGPAT 1096

Query: 724  QAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAAT- 782
             +P+  P P + + P  +G       + PP +     PA+ PP  +   A  PP  A T 
Sbjct: 1097 PSPKGAPMPPAATPPSPKGGL-----ATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTT 1151

Query: 783  -------PYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPR--MLTSGSHPQA 833
                   P        P+  P  PA   P    P   +  P  +  P     T  S    
Sbjct: 1152 PAATPPSPKGGLATPPPKGAPTTPAATPPS---PKGGLATPSPKGAPTTPAATPPSPKGG 1208

Query: 834  IVSSS---TPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQ-----PATTPTGSQPQ 885
            + + S    P  P+A  P+P+   AT     P  A    A  P      PAT P    P 
Sbjct: 1209 LATPSPKGAPTTPAATPPSPKGGLAT---PSPKGAPTTPAATPPSPKGGPATPPPKGAPT 1265

Query: 886  SQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAV 945
               A P  ++      PH G+         P     TPPS   GP+   P+ +   PAA 
Sbjct: 1266 PPAATPPSLKGGLATPPHKGA---------PNPAVVTPPSPKGGPATSPPKGAPTPPAAT 1316

Query: 946  YAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHP----------PQ 995
                    P G                +   PP  GAP PP V    P          P 
Sbjct: 1317 -----PPSPKG----------------SPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPS 1355

Query: 996  SHGGP----------PQGAVP-QSGVPALSASTPSPYPYIGHPQGE---------QPGQA 1035
            S GGP          P  A P   G PA++  +P   P I  P+G+          P +A
Sbjct: 1356 SKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKA 1415

Query: 1036 PGFP----GGA----DDRIPPLPPPGELK 1056
            P  P    G A     D  PP   P  LK
Sbjct: 1416 PATPVTREGAATPSKGDLTPPAVTPVSLK 1444



 Score = 97.1 bits (240), Expect = 8e-20
 Identities = 188/775 (24%), Positives = 259/775 (33%), Gaps = 119/775 (15%)

Query: 335  SGRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGR--PGLSSLPPRG-----PHHL 387
            S +  P+  S +G   P P      P+GG    S +G    P ++   P+G     P   
Sbjct: 972  SPKGGPATPSPKGAPTP-PAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPK 1030

Query: 388  DNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGET--SVPPPPAVGRMY 445
              S+P P +      G P+        P   A TL SP   P+  +    P PPA     
Sbjct: 1031 GASTP-PAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAA---- 1085

Query: 446  PPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTD 505
             P SPK     P     P PP  +  P+    +        P   + +P SPK  LA   
Sbjct: 1086 TPPSPKGGPATPSPKGAPMPPAATP-PSPKGGLATPPHKGAPTTPAATPPSPKGGLATPP 1144

Query: 506  VKELSTKEPGRTLEPQE-LA----RIAGKVPGLQNEQKRFQLEELRKFGAQFK---LQPS 557
             K   T        P+  LA    + A   P       +  L      GA        PS
Sbjct: 1145 PKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1204

Query: 558  -----SSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPL 612
                 ++P     P  P      PKG      GL T  P G+P +      S K      
Sbjct: 1205 PKGGLATPSPKGAPTTPAATPPSPKG------GLATPSPKGAPTTPAATPPSPKGGPATP 1258

Query: 613  APSGGTEGPEQPPPPC------PSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEF 666
             P G    P   PP        P   G+P   ++       GP     K +   P A   
Sbjct: 1259 PPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPP 1318

Query: 667  NP-------------TKPLLSVNKSTSTPTSP--------GPRTHST---PSIPVLTAGQ 702
            +P             T P ++      TPT P        GP T S+   P+ P  T   
Sbjct: 1319 SPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSH 1378

Query: 703  SGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGA-----KGSLPPQRSD 757
             G   P      P+   GPA+ +P+    P S +V     K   A     +G+  P + D
Sbjct: 1379 KG--GPAMTPPSPK--RGPAIPSPK--GDPTSPAVIPLSPKKAPATPVTREGAATPSKGD 1432

Query: 758  QHQPASAPPMMQAAAAAGPPLVA-ATPYSSYIPYNPQQFPGQPAMMQPMAHYP----SQP 812
               PA  P  ++ A A   P    ATP S   P  P   P  P+  +P A       S P
Sbjct: 1433 LTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTP--PSPKEPPAPKQVATSSSP 1490

Query: 813  VFAPMLQSNPRMLTSGSHPQAIVSS--STPQYPSAEQPTPQALYATVHQSYPHHATQLHA 870
              AP   + P  + + + P  I SS    P  PS+ +         + +  P       A
Sbjct: 1491 KKAP---ATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEA 1547

Query: 871  HQPQPATTP----TGSQPQSQHAAPSPVQHQAGQAP------HLGSGQPQQNLYHPGALT 920
              P   T P    T + P  + A  +P   +A   P      + G+  P++ L  P A+T
Sbjct: 1548 LIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPP-AVT 1606

Query: 921  GTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHP 980
               P   P P A +P S    PA          P G      VT + ++   T+      
Sbjct: 1607 SPSPKEAPTPPAVTPPSPEKGPAT-------PAPKGTPTSPPVTPSSLKDSPTS------ 1653

Query: 981  GAPHPPQV---MLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQP 1032
                P  V   M    PQ+  G P    P +    L A  P   P I  P  + P
Sbjct: 1654 ----PASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGP 1704



 Score = 88.2 bits (217), Expect = 4e-17
 Identities = 168/704 (23%), Positives = 236/704 (33%), Gaps = 110/704 (15%)

Query: 391  SPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGE---TSVPPPPAVGRMYPP 447
            S  P   A     G S  +  A   L G  +L+ P N P  E   T++P  P      P 
Sbjct: 652  SADPAGVAPTTAKGTSTYTTTASPFLEGTVSLA-PKNHPVKEGTLTTLPLVPTASENCPV 710

Query: 448  RSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAP--TD 505
                    AP++     P I  +VP  S S+P   +   PG   +   S   +LAP  + 
Sbjct: 711  APSPQNTCAPLATLVLAPEIPKSVP--SPSLPPAGT--PPGTKKVDGISHTSALAPVASS 766

Query: 506  VKELSTKEPGRTLEPQE---LARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN 562
             KE  T++ G +        L  +A     L             K G+     P  +  +
Sbjct: 767  PKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSS 826

Query: 563  SLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPE 622
             + P     L E     +   D   T+    SP     +         PL+P G T  P+
Sbjct: 827  PVSPVEASFLPENSLSFQGSKDSPATTH---SPTPPSPKGAPTPSAVTPLSPKGVTLPPK 883

Query: 623  QPPPPCPSQTGSPPVGLIKGEDKDEGPVA---EQVKKSTLNPNAKEFN--------PTKP 671
            + P P       P  G      K    ++      KK+   P  K           PT P
Sbjct: 884  ETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPP 943

Query: 672  LLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQY-------ISYIPQIHMGPAVQ 724
              +       P +P P+   TP      + + G  +P          +  P    GPA  
Sbjct: 944  AATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATP 1003

Query: 725  APQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGP-PLVAATP 783
            +P+  P P + + P      +G+  + P  +     PA+ PP  + + AA P P  A T 
Sbjct: 1004 SPKGAPTPPAVTPPSP----KGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTT 1059

Query: 784  YSSYIPYNPQQFPGQPAMM---QPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
             ++ +P +P+  P  P++     P A  P  P   P   S                   P
Sbjct: 1060 PAATLP-SPKGGPATPSLKGAPTPPAATPPSPKGGPATPS---------------PKGAP 1103

Query: 841  QYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQ 900
              P+A  P+P+   AT     PH             TTP  + P  +    +P    A  
Sbjct: 1104 MPPAATPPSPKGGLATP----PHKGAP---------TTPAATPPSPKGGLATPPPKGAPT 1150

Query: 901  APHLGSGQPQQNLYHP---GALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGF 957
             P      P+  L  P   GA T TP + PP     SP+     P+          P G 
Sbjct: 1151 TPAATPPSPKGGLATPPPKGAPT-TPAATPP-----SPKGGLATPS----------PKGA 1194

Query: 958  TNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQ-SGVPALSAS 1016
                  T    + G+  A P   GAP  P      PP   GG    A P   G P   A+
Sbjct: 1195 PTTPAATPPSPKGGL--ATPSPKGAPTTPAAT---PPSPKGGL---ATPSPKGAPTTPAA 1246

Query: 1017 TPSPYPYIGHPQGEQPGQAPGFPGGADDRIPPLPPPGELKIVLA 1060
            TP P P  G P    P  AP          PP   P  LK  LA
Sbjct: 1247 TP-PSPK-GGPATPPPKGAP---------TPPAATPPSLKGGLA 1279



 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 161/716 (22%), Positives = 222/716 (31%), Gaps = 142/716 (19%)

Query: 417  RGAKTLSSPSNRPSGETSVPPPPAVG---RMYPPRSPKSAAPAPISASCPEPPIGS---- 469
            +G  T+SS +  PSG  +V    ++     +    SP +    P+ A  P   +G+    
Sbjct: 383  KGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLV 442

Query: 470  --------AVPTSSASIP--VTSSVSDPGVGSISPASPK-ISLAPTDVKELSTKEPGRTL 518
                    A PT++  +   V+  +S   + +I P SP  + +AP   KE ST +   TL
Sbjct: 443  VTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPST-QVATTL 501

Query: 519  ---------EPQELARIAGKVPGLQNEQKRFQLEELRKFGAQF---------KLQPS--- 557
                     +P++L  +   V      QK  Q       GA F         K  P+   
Sbjct: 502  RIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLP 561

Query: 558  ---SSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPM--GSPVSSKTESVSDKEDKPPL 612
               ++P+NS          E P   E  +      EP+  G P SS T  +        +
Sbjct: 562  LVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLG-VNSSASV 620

Query: 613  APSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTL------------- 659
              +    GP+   P   S   +P V     E  D   VA    K T              
Sbjct: 621  IKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGT 680

Query: 660  ------NPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISY 713
                  N   KE   T   L    S + P +P P+    P   ++ A       P+    
Sbjct: 681  VSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLA-------PEIPKS 733

Query: 714  IPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAA 773
            +P   + PA   P         S          +    P + S     AS+   +   A 
Sbjct: 734  VPSPSLPPAGTPPGTKKVD-GISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLAD 792

Query: 774  AGPPL-VAATPYSSYIPYNPQQFPGQPAMMQPMAHY--PSQPVFAPMLQSNPRMLTSGSH 830
            +  PL V+ +P +      P    G      P+ +   P  PV A  L  N         
Sbjct: 793  SPSPLGVSVSPQTK----RPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKD 848

Query: 831  PQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAA 890
              A   S TP  P    PTP A    V    P   T        P  TPT S        
Sbjct: 849  SPATTHSPTPPSPKGA-PTPSA----VTPLSPKGVTL------PPKETPTPSVVNLPFPK 897

Query: 891  PSPVQHQAGQAPHLG--SGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAI 948
              P      QAP L   S  P++        T  P  +P  PS                 
Sbjct: 898  EGPATPAPKQAPALSMTSSSPKK-----ARATPAPKGIPASPS----------------- 935

Query: 949  HHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQS 1008
                 P G                  AP P    P  P+     P       P  A P S
Sbjct: 936  -----PKG------------------APTPPAATPPSPKGGPATPSPKWAPTPPAATPPS 972

Query: 1009 --GVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRIPPLPPPGELKIVLAAT 1062
              G PA  +   +P P    P   + G A   P GA    PP   P   K   AAT
Sbjct: 973  PKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAP--TPPAVTPPSPKGSPAAT 1026



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 78/327 (23%), Positives = 115/327 (35%), Gaps = 63/327 (19%)

Query: 381  PRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA 440
            P  P   + SSP P        G PS   PK +  +  A T  SP   P+     PP P 
Sbjct: 1571 PATPSSKEASSP-PAVTPSTYKGAPS---PK-ELLIPPAVTSPSPKEAPTPPAVTPPSPE 1625

Query: 441  VGRMYP---------PRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGS 491
             G   P         P +P S   +P S +     +G+ VP +S  +P     +      
Sbjct: 1626 KGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVL 1685

Query: 492  ISPA--SPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFG 549
            ++PA  S  I  APT  K   TK+   T  P          P  +N  K           
Sbjct: 1686 VAPAPESTPIITAPTR-KGPQTKKSSATSPP------ICPDPSAKNGSK----------- 1727

Query: 550  AQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDK 609
                      P +++ P P   ++++     K  D   + +   +P  SK  +       
Sbjct: 1728 ---------GPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKAST------- 1771

Query: 610  PPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPT 669
             PL  +   +   +P     S   SPPV L         P+A     +   P  ++F P+
Sbjct: 1772 -PLTAAAFEKVLPKPESASVSAAPSPPVSL---------PLAPSPVPTL--PPKQQFLPS 1819

Query: 670  KPLLSVNKSTSTPTSPGPRTHSTPSIP 696
             P L V +S S P +P       P IP
Sbjct: 1820 SPGL-VLESPSKPLAPADEDELLPLIP 1845



 Score = 40.0 bits (92), Expect = 0.012
 Identities = 136/646 (21%), Positives = 210/646 (32%), Gaps = 101/646 (15%)

Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPP----------PAVGRMYPPRSPKSAA 454
           P   +  A  P+  A ++++   +P    ++PPP           A  +  P  SP + A
Sbjct: 17  PQPQAETAVLPMSSALSVTAALGQPG--PTLPPPCSPAPQQCPLSAANQASPFPSPSTIA 74

Query: 455 PAPISASCPEPPIGSAVPTSSAS--------------IPVTSSVSDP-------GVGSIS 493
             P+    P+   G+A+P  +A                P   +++ P       G  S S
Sbjct: 75  STPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSS 134

Query: 494 PASPKISLAPTDVKELSTKEPGRTLEPQELA------RIAGKVPGLQNEQKRFQLEELRK 547
                ++LAP  V++ S   P     P  +A       I    P   +E K      L K
Sbjct: 135 APLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPK----TNLNK 190

Query: 548 FGAQFKLQPSSSPENSLDPFPPRILKEEP---KGKEKEVDGLLTSEPMGSPVSS------ 598
             ++    P  +P       PP I+   P         +   + S P  +P ++      
Sbjct: 191 VPSEVVPNPKGTPS------PPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASP 244

Query: 599 --KTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKK 656
             K  ++S     P    S   +GP  PP      T S PV  +    K  GP       
Sbjct: 245 QVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPV--VTSSQKTAGPNTPPDFP 302

Query: 657 STLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQS--GLYSPQYISYI 714
            +L  +    +      S   S       GP   S P++  ++   S  G   P   S I
Sbjct: 303 ISLGSHLAPLHQ-----SSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVI 357

Query: 715 PQI----HMGPAVQAPQMYPYPVSNSVPGQQGKYR-GAKGSLPPQRSDQHQPASAPPMMQ 769
           P +     + PA  A      P  +  P           GSL    S    P ++  +  
Sbjct: 358 PPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKS 417

Query: 770 AA-AAAGPPLVAATPYSS-----YIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPR 823
           +  A    PLVA  P SS      +  NP      P     +A   S P     + S P 
Sbjct: 418 SPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPP-----MSSGPI 472

Query: 824 MLTSGSHPQAIVSSS-TPQYPSAEQPTPQALYATVHQSYPHHATQLHAH--QPQPATTPT 880
                + P A+V +   P+ PS +  T   +  +     P     L +      P     
Sbjct: 473 SNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDL 532

Query: 881 GSQPQSQHAAP-SPVQHQAGQAPH-------LGSGQPQQNLYHPGALTGTPPSLPPGPSA 932
            + P S   AP SP   QAG           L    P+ +       T + P +P  P A
Sbjct: 533 QTVPASLEGAPFSPA--QAGLTTKKDPTVLPLVQAAPKNSPSFQS--TSSSPEIPLSPEA 588

Query: 933 QSPQSSFPQPAAV-YAIHHQQLPHGFTNMAHVTQAHVQTGITAAPP 977
              + S  +P  +         P G  + A V +     G  +A P
Sbjct: 589 TLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGP 634



 Score = 39.7 bits (91), Expect = 0.015
 Identities = 35/122 (28%), Positives = 48/122 (39%), Gaps = 9/122 (7%)

Query: 4    PQPLQQPSQPQQPPPTQQA--VARRPPGGTSPPNGGLPGPLATSAAPPGP-----PAAAS 56
            P P   P+ P   PP+ +       P G  +PP    P P  + AA P P     P AA+
Sbjct: 980  PSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAAT 1039

Query: 57   PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPG--AAAIGSARGQSTGKGPPQSPVF 114
            P     + A + L +GA    A   P P+     P    A    A    + KG P +P  
Sbjct: 1040 PPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP 1099

Query: 115  EG 116
            +G
Sbjct: 1100 KG 1101



 Score = 39.7 bits (91), Expect = 0.015
 Identities = 39/124 (31%), Positives = 46/124 (37%), Gaps = 22/124 (17%)

Query: 4    PQPLQQPSQPQQPPPTQQAVARRPPGG--TSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
            P P   P+ P   PP+       P GG  T PP G    P AT  +P G  A  SP   P
Sbjct: 1143 PPPKGAPTTPAATPPS-------PKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAP 1195

Query: 62   VAAAGS------GLR----RGAEGILAPQPPPPQQHQERP---GAAAIGSARGQSTGKGP 108
               A +      GL     +GA    A  PP P+     P   GA    +A   S   GP
Sbjct: 1196 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGP 1255

Query: 109  PQSP 112
               P
Sbjct: 1256 ATPP 1259



 Score = 39.7 bits (91), Expect = 0.015
 Identities = 31/112 (27%), Positives = 39/112 (34%), Gaps = 6/112 (5%)

Query: 3    KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPV 62
            K  P   P +    PP     + +   GT PP G    P  T  +P G P    P   P 
Sbjct: 1298 KGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTL--PATTPS 1355

Query: 63   AAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQS--TGKGPPQSP 112
            +  G       EG   P   P   H+  P        RG +  + KG P SP
Sbjct: 1356 SKGGPTTPSSKEGPTPPAATP--SHKGGPAMTPPSPKRGPAIPSPKGDPTSP 1405



 Score = 38.5 bits (88), Expect = 0.034
 Identities = 35/116 (30%), Positives = 44/116 (37%), Gaps = 14/116 (12%)

Query: 4    PQPLQQPSQPQQPPPTQQAVARRPP--GGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
            P P   P  P   PP+ +     PP  G  + P    P P    A PP   A  +P   P
Sbjct: 1097 PSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1156

Query: 62   VAAAGSGLR----RGAEGILAPQPPPPQQHQERPGAAAIGSARG-QSTGKGPPQSP 112
             +  G GL     +GA    A  PP P+      G  A  S +G  +T    P SP
Sbjct: 1157 PSPKG-GLATPPPKGAPTTPAATPPSPK------GGLATPSPKGAPTTPAATPPSP 1205



 Score = 38.5 bits (88), Expect = 0.034
 Identities = 34/113 (30%), Positives = 47/113 (41%), Gaps = 11/113 (9%)

Query: 4    PQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGP-LATSAAPPGPPAAASPCLGPV 62
            P P   P+ P   PP+ +       G  +PP+ G P P + T  +P G PA + P   P 
Sbjct: 1258 PPPKGAPTPPAATPPSLKG------GLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPT 1311

Query: 63   -AAAGSGLRRGAEGILAPQ--PPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
              AA     +G+ G   P+  P PP      P       A   S+ KG P +P
Sbjct: 1312 PPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSS-KGGPTTP 1363



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 35/119 (29%), Positives = 42/119 (35%), Gaps = 19/119 (15%)

Query: 4    PQPLQQPSQPQQPPPTQQA--VARRPPGGTSPPNGGLPGPLATSAAP-----PGPPAAA- 55
            P P   P+ P   PP+ +       P    +PP    P P    A P     P PPAA  
Sbjct: 934  PSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATP 993

Query: 56   -SPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQST-GKGPPQSP 112
             SP  GP   +  G         AP PP       +   AA    +G ST     P SP
Sbjct: 994  PSPKGGPATPSPKG---------APTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSP 1043



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 34/119 (28%), Positives = 41/119 (34%), Gaps = 19/119 (15%)

Query: 4    PQPLQQPSQPQQPPPTQQ---AVARRPPGGTSPPNGGLPGPLATSAAP-----PGPPAAA 55
            P P    + P   PP+ +   A    P G  + P   LP P    A P     P PPAA 
Sbjct: 1027 PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAAT 1086

Query: 56   --SPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
              SP  GP   +  G         AP PP       + G A        +T    P SP
Sbjct: 1087 PPSPKGGPATPSPKG---------APMPPAATPPSPKGGLATPPHKGAPTTPAATPPSP 1136



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 33/121 (27%), Positives = 43/121 (35%), Gaps = 9/121 (7%)

Query: 4    PQPLQQPSQPQQPPPTQQA--VARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
            P P   P+ P   PP+ +       P G  + P    P P    A PP   A   P   P
Sbjct: 1212 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP 1271

Query: 62   VAAAGSGL----RRGAEGILAPQPPPPQ--QHQERPGAAAIGSARGQSTGKGPPQSPVFE 115
             +  G GL     +GA       PP P+       P  A    A    + KG P +P  +
Sbjct: 1272 PSLKG-GLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPK 1330

Query: 116  G 116
            G
Sbjct: 1331 G 1331



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 27/105 (25%), Positives = 36/105 (34%), Gaps = 9/105 (8%)

Query: 6    PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAA 65
            P      P  PPP     A  PP  T P   G P   AT+ +  G P   S   GP   A
Sbjct: 1317 PPSPKGSPGTPPPKG---APTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPA 1373

Query: 66   GSGLRRGAEGILAPQP------PPPQQHQERPGAAAIGSARGQST 104
             +   +G   +  P P      P P+     P    +   +  +T
Sbjct: 1374 ATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPAT 1418



 Score = 35.0 bits (79), Expect = 0.38
 Identities = 37/125 (29%), Positives = 45/125 (36%), Gaps = 24/125 (19%)

Query: 4    PQPLQQP------SQPQQ----PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAP----- 48
            P P Q P      S P++    P P     +  P G  +PP    P P    A P     
Sbjct: 903  PAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWA 962

Query: 49   PGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKG- 107
            P PPAA  P   P     +   +GA    A  PP P+      G  A  S +G  T    
Sbjct: 963  PTPPAATPP--SPKGGPATPSPKGAPTPPAATPPSPK------GGPATPSPKGAPTPPAV 1014

Query: 108  PPQSP 112
             P SP
Sbjct: 1015 TPPSP 1019



 Score = 35.0 bits (79), Expect = 0.38
 Identities = 34/120 (28%), Positives = 43/120 (35%), Gaps = 18/120 (15%)

Query: 10   PSQPQQPPPTQQA--VARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGS 67
            P+ P   PP+ +       P G   PP    P P    A PP   A  +P   P +  G 
Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG- 1138

Query: 68   GLR----RGAEGILAPQP---------PPPQQHQERPGAAAIGSARGQST--GKGPPQSP 112
            GL     +GA    A  P         PPP+     P A       G +T   KG P +P
Sbjct: 1139 GLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1198



 Score = 35.0 bits (79), Expect = 0.38
 Identities = 28/121 (23%), Positives = 43/121 (35%), Gaps = 7/121 (5%)

Query: 4    PQPLQQPSQPQQPPPTQQAVARRP---PGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
            P P   P+ P   P + +     P    G  +P  G L  P  T  +    PA ++P  G
Sbjct: 1396 PSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGG 1455

Query: 61   PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
            P   +     +G   + A  PP P++       A   S +       P  +P    V  +
Sbjct: 1456 PATPSS----KGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPS 1511

Query: 121  S 121
            S
Sbjct: 1512 S 1512



 Score = 34.7 bits (78), Expect = 0.49
 Identities = 67/286 (23%), Positives = 105/286 (36%), Gaps = 44/286 (15%)

Query: 796  PGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQAL-Y 854
            PG+     P      Q +  P  ++    ++S     A +    P  P    P PQ    
Sbjct: 2    PGEATETVPATE---QELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPL 58

Query: 855  ATVHQSYPHHA------TQLHAHQPQPAT---TPTGSQPQSQHAAPSPVQHQAGQAPHLG 905
            +  +Q+ P  +      T L    PQ ++    P G+ P++    P+ +      A  L 
Sbjct: 59   SAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAA-LA 117

Query: 906  SGQPQQNLYHPGALTGTPPSLPP------GPSAQSPQSSFP-----QPAAVYAIHHQQLP 954
               P   +  P  L GTP S  P       P +    S+FP      P +V       + 
Sbjct: 118  LASP---MIAP-TLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSV- 172

Query: 955  HGFTNMAHVTQAHVQTGITAAPP---PHP-GAPHPPQVMLLHPPQSHGGPPQGAVPQSGV 1010
               T  A +  +  +T +   P    P+P G P PP ++   P   H   P  ++ QSGV
Sbjct: 173  --ITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVP--YHCVTPMASI-QSGV 227

Query: 1011 PALSASTPSPYPYIGHPQGEQPG-----QAPGFPGGADDRIPPLPP 1051
             +L  +TP+    I  PQ +         +P  PG    + P  PP
Sbjct: 228  ASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPP 273



 Score = 34.7 bits (78), Expect = 0.49
 Identities = 32/127 (25%), Positives = 41/127 (32%), Gaps = 20/127 (15%)

Query: 4    PQPLQQPSQPQQPPPTQQA--VARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
            P P   P+ P   PP+ +       P G  + P    P P    A P    A  +P   P
Sbjct: 1189 PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1248

Query: 62   VAAAGSGLRRGAEGILAPQPP-------------PPQQHQERPGAAAIGSARG---QSTG 105
             +  G       +G  AP PP             PP +    P      S +G    S  
Sbjct: 1249 PSPKGGPATPPPKG--APTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPP 1306

Query: 106  KGPPQSP 112
            KG P  P
Sbjct: 1307 KGAPTPP 1313



 Score = 32.0 bits (71), Expect = 3.2
 Identities = 25/98 (25%), Positives = 34/98 (34%), Gaps = 6/98 (6%)

Query: 16   PPPTQQAVARRPP-GGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAE 74
            PP  +   A  PP G  +PP    P P  +   PP   A   P + P +  G+       
Sbjct: 1294 PPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATT 1353

Query: 75   GILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
                  P  P   +     AA  S +G     GP  +P
Sbjct: 1354 PSSKGGPTTPSSKEGPTPPAATPSHKG-----GPAMTP 1386


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score =  104 bits (260), Expect = 4e-22
 Identities = 199/800 (24%), Positives = 279/800 (34%), Gaps = 133/800 (16%)

Query: 357  REGP-RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRP 415
            R GP R     S +   RP  S    R P    N+SPGP S   G   G +R  P  Q+ 
Sbjct: 76   RAGPTRSAGTSSRNPASRPPASGRGERAPP-AKNTSPGPVSSP-GRASGTTRPGPLGQKG 133

Query: 416  LR---------GAKT-------LSSPSNRP-SGETSVPPPPAVGRMYPPRSPKSAAPAPI 458
            LR         G  T       LS+ + R  SG T   P PA+ R       +   P P 
Sbjct: 134  LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 193

Query: 459  SASCPEPPI-GSAVPTSSASIPVTSSVS-------DPGVGSISPASPKISLAPTDVKELS 510
             ++ P PP  G     SSAS   T+  S         G G   PAS  +S + T +   +
Sbjct: 194  PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253

Query: 511  TKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQF-----------------K 553
               P     P+  A  +   P      +  Q+   RK  A                   K
Sbjct: 254  RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTK 313

Query: 554  LQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLA 613
             +P   P+N+  P P  +    P         L T  P+  P  S   S+      P   
Sbjct: 314  ARPVPPPDNAATPLPATLPPSPP---------LATPLPLAPPSPSAPPSLQTLPSPPATP 364

Query: 614  PSGGTEGPEQPPPPCPSQTGS-PPVGLIKGEDKDE-----GPVAEQVKKSTLNPNAKEFN 667
            PS        PP   P    + PP+ +              P+A    ++T +  +    
Sbjct: 365  PSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQ 424

Query: 668  PTKPLLSVN--KSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQA 725
             T   L+++  ++ ++ TSP     + P  P L A  S   SP       Q  + PAV  
Sbjct: 425  ATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPL-----QTSLSPAVSP 479

Query: 726  PQ----MYPYPVSNSVPGQQGKYRGAKGSLPPQRSD--------QHQPAS--APPMMQAA 771
                  ++P    +S+     +   +   +PP  +         Q  PAS   PP+    
Sbjct: 480  LSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLP 539

Query: 772  AAAGPPLVAA-----TPYSSYIPYN---PQQFPGQPAMMQPMAHYPSQ----PVFAPMLQ 819
            + A PPL  A     TP+    P     P Q P  P +  P    PS     P  AP   
Sbjct: 540  SLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSP-LTTPPPETPSSIATPPPQAPPAL 598

Query: 820  SNPRMLTSGSHPQAIVSSSTPQYP------------SAEQPTPQALYATVHQSYPHHATQ 867
            ++P +    S P + +++  PQ P            S     P +  AT     P+ A  
Sbjct: 599  ASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPN-ALA 657

Query: 868  LHAHQP--QPATTPTGSQPQSQHAAP--SPVQHQAGQAPHLGSGQPQQNLYHPGALTGTP 923
            +H  Q    P  +P    P S  A+P  SP      QAP   +  P Q       +  +P
Sbjct: 658  VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ-------VPPSP 710

Query: 924  PSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPH--PG 981
            P+ PP   + +P    P P A   +     P     M+           +A PPP   P 
Sbjct: 711  PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSP----------SATPPPRVPPL 760

Query: 982  APHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGG 1041
               PP  +   PP S    P    P    PAL+  TP P   +  P    PGQAP  P  
Sbjct: 761  LAAPPLQVPPSPPASLPMSPLAKPPPQAPPALA--TP-PLQALPSPPASFPGQAPFSPSA 817

Query: 1042 ADDRIPPLPPPGELKIVLAA 1061
            +    P   PP +   VLAA
Sbjct: 818  SLPMSPLATPPPQAPPVLAA 837



 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 160/670 (23%), Positives = 225/670 (33%), Gaps = 102/670 (15%)

Query: 440  AVGRMYPPRSPKSAAPAPISASCPEPPIGSA---VPTSSASI---PVTSSVSDPGVGSIS 493
            A  R    R+P    P P  +  P PP+  A   V  ++ ++   P+       G  +I 
Sbjct: 12   AAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71

Query: 494  PASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFK 553
             ++P+    PT     S++ P     P    R   + P  +N                  
Sbjct: 72   ESAPR--AGPTRSAGTSSRNPAS--RPPASGR-GERAPPAKNTSP--------------- 111

Query: 554  LQPSSSPENSLDPFPPRILKEEP---KGKEKEVDGLLTSEPMGSPVSS----KTESVSDK 606
              P SSP  +     P  L ++      +E    G  T  P  S +S+     T   +  
Sbjct: 112  -GPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG 170

Query: 607  EDKPPLAPSGGTEGPEQP-PPPCPSQTGSPPVGLIKGEDKDEGP---VAEQVKKSTLNPN 662
               P +A      G E   P P PS    PP          EGP   V+   + ST  P+
Sbjct: 171  TPSPAMARRSRAAGTEVGLPRPAPSARPRPPT---------EGPRKSVSSASEHSTTEPS 221

Query: 663  -AKEFNP----------TKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTA-----GQSGLY 706
             A    P          ++ L S     S+P   GP    TP  P   +     G   L 
Sbjct: 222  PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR 281

Query: 707  SPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPP 766
             PQ     P+    PA+      P     + P   G    A+   PP  +    PA+ PP
Sbjct: 282  PPQVTP--PRKDAAPALGPLSSSPL----ATPSPSG--TKARPVPPPDNAATPLPATLPP 333

Query: 767  MMQAAA--AAGPPLVAATPYSSYIPYNPQQFPGQ--PAMMQPMAHYPSQPVFAPMLQSNP 822
                A      PP  +A P    +P  P   P Q  P+M  P    P      P +Q  P
Sbjct: 334  SPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQV-P 392

Query: 823  RMLTSGS---HPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTP 879
              LTS S    P  +  SS     S   PT QA ++ +  S P           +PA+TP
Sbjct: 393  HSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMS-PRQTQASLTSPSRPASTP 451

Query: 880  TGSQP-QSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGP-------- 930
              S P Q+  + P+    Q   +P +        ++   AL+      P  P        
Sbjct: 452  PDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPP 511

Query: 931  ----SAQSPQSSFPQPAAVYAIHHQQLPHGF-----TNMAHVTQAHVQTGITAAPPPHPG 981
                S+ +P S    PA++     + LP        T  A +T  H++T    AP P   
Sbjct: 512  LETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQA 571

Query: 982  APHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGG 1041
             P P        P S   PP  A P    P L      P   +  P    P QAP     
Sbjct: 572  PPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATP----PPQAPPXLAL 627

Query: 1042 ADDRIPPLPP 1051
               + PP PP
Sbjct: 628  PPLQAPPSPP 637



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 72/304 (23%), Positives = 108/304 (35%), Gaps = 34/304 (11%)

Query: 374 PGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSR-----MSPKAQRPLRGAKTLSSPSNR 428
           P   + PP  P         P   A  +   PS      MSP A  P R    L++P  +
Sbjct: 708 PSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQ 767

Query: 429 --PSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPI---GSAVPTSSASIPVTSS 483
             PS   S+P  P      PP++P + A  P+ A  P PP    G A  + SAS+P++  
Sbjct: 768 VPPSPPASLPMSPLAKP--PPQAPPALATPPLQA-LPSPPASFPGQAPFSPSASLPMSPL 824

Query: 484 VSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGK------VPGLQNEQ 537
            + P       A+P + + P+     + + P R   P     ++G        PG     
Sbjct: 825 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 884

Query: 538 KRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVS 597
            R     L          P  +  +S     P  L+    G E    G   S P  + ++
Sbjct: 885 SRSPSSTLS--------GPDLAGHSSSATSTPEELRGYDSGPE---GGAAASPPPDAELA 933

Query: 598 SKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKS 657
           +   +   +   PPLA      G    P P P  TG      +    + EGP +      
Sbjct: 934 ACHPAAWSRGPAPPLA----FRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG 989

Query: 658 TLNP 661
            L+P
Sbjct: 990 ALDP 993



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 43/134 (32%), Positives = 51/134 (38%), Gaps = 30/134 (22%)

Query: 4   PQPLQQPSQP--QQPPPTQQAVA----RRPPGGTSPPNGGLP----GPLATS-------- 45
           P PLQ P  P    PP T  ++A    + PP   SPP  GLP     PLAT         
Sbjct: 566 PCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXL 625

Query: 46  -----AAPPGPPAAASPCLGPVAAAGSGLRRG-----AEGILAPQPPPPQQHQERPGAAA 95
                 APP PP  ASP L P+A               +   +P P PP Q    P A+ 
Sbjct: 626 ALPPLQAPPSPP--ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 683

Query: 96  IGSARGQSTGKGPP 109
             S       + PP
Sbjct: 684 PVSPSATPPSQAPP 697



 Score = 37.7 bits (86), Expect = 0.058
 Identities = 33/123 (26%), Positives = 43/123 (34%), Gaps = 18/123 (14%)

Query: 6   PLQQPSQPQQPPPTQQAVARRPPGGTS------------PPNGGLPGPLATSAAPPGPPA 53
           PLQ P  P   PP        P    +            PP+  +  P +  A+PP  P+
Sbjct: 629 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 688

Query: 54  AASPCLGPVAAAGSGLR----RGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109
           A  P   P + A   L+      A   ++P   PP   Q  P  AA       S    PP
Sbjct: 689 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP--QAPPPLAAPPLQVPPSPPASPP 746

Query: 110 QSP 112
            SP
Sbjct: 747 MSP 749



 Score = 37.0 bits (84), Expect = 0.099
 Identities = 39/122 (31%), Positives = 48/122 (39%), Gaps = 30/122 (24%)

Query: 13  PQQPP--PTQQAVARRPPGGTSPPNGGLPGP---LATSAAPPGPP--AAASPCLGPVAAA 65
           P  PP  PT QA  RRPP  T  P+  + GP   LA +  PP PP  + +S   GP  A 
Sbjct: 843 PPSPPASPTLQA-PRRPP--TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 899

Query: 66  GS-----------GLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVF 114
            S           G   G EG  A  PPP          A + +    +  +GP     F
Sbjct: 900 HSSSATSTPEELRGYDSGPEGGAAASPPPD---------AELAACHPAAWSRGPAPPLAF 950

Query: 115 EG 116
            G
Sbjct: 951 RG 952



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 34/112 (30%), Positives = 43/112 (38%), Gaps = 6/112 (5%)

Query: 3   KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAP-PGPPAAASPCLGP 61
           KP+ LQ    PQ  PP + A     P  +SP     P P  T A P P P  AA+P   P
Sbjct: 273 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPL--ATPSPSGTKARPVPPPDNAATPL--P 328

Query: 62  VAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP-QSP 112
                S        +  P P  P   Q  P   A   ++   +   PP Q+P
Sbjct: 329 ATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAP 380



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 32/113 (28%), Positives = 39/113 (34%), Gaps = 24/113 (21%)

Query: 2   LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLP--GPLATSAAPPGPPAAASPCL 59
           L   PLQ P  P   PP   +    PP    PP    P   P +  A+PP  P+A  P  
Sbjct: 699 LAAPPLQVPPSPPASPPMSPSAT--PPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPR 756

Query: 60  GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
            P   A   L+      + P PP               S       K PPQ+P
Sbjct: 757 VPPLLAAPPLQ------VPPSPP--------------ASLPMSPLAKPPPQAP 789



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 38/130 (29%), Positives = 48/130 (36%), Gaps = 22/130 (16%)

Query: 2   LKPQPLQQPSQPQQPPPTQQAVA---RRPPGGTSPPNGGLPGPLATS-----AAPP--GP 51
           L   PLQ P  P   PP   +     R PP   +PP    P P A+      A PP   P
Sbjct: 730 LAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAP 789

Query: 52  PAAASPCL-----GPVAAAGSG-LRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTG 105
           PA A+P L      P +  G       A   ++P   PP      P A  + +A      
Sbjct: 790 PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP------PQAPPVLAAPLLQVP 843

Query: 106 KGPPQSPVFE 115
             PP SP  +
Sbjct: 844 PSPPASPTLQ 853



 Score = 31.6 bits (70), Expect = 4.2
 Identities = 29/91 (31%), Positives = 34/91 (37%), Gaps = 13/91 (14%)

Query: 16   PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEG 75
            PPP  +  A  P   +  P      PLA   AP G P    P  GP +A G       EG
Sbjct: 926  PPPDAELAACHPAAWSRGP----APPLAFRGAP-GAPLPWPPATGPGSADGLCTIYETEG 980

Query: 76   ILAPQPPPPQQHQERPGAAAIGSARGQSTGK 106
                    P+     PGA   G + G S GK
Sbjct: 981  --------PESATPAPGALDPGPSPGTSGGK 1003



 Score = 30.4 bits (67), Expect = 9.2
 Identities = 20/73 (27%), Positives = 29/73 (39%), Gaps = 2/73 (2%)

Query: 11  SQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLR 70
           S P +  P+ +   R P   + P   GL         PP   AA  P LGP++++     
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA--PALGPLSSSPLATP 307

Query: 71  RGAEGILAPQPPP 83
             +     P PPP
Sbjct: 308 SPSGTKARPVPPP 320


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 98.2 bits (243), Expect = 4e-20
 Identities = 178/751 (23%), Positives = 253/751 (33%), Gaps = 128/751 (17%)

Query: 381  PRGPH--HLDNSSPGP-GSEARGINGGPSRMSPKAQRPLRGAKTL-----SSPSNRPSGE 432
            P+G H   +    PGP   EA+ +     ++ P+ + PL     L      SP + P  E
Sbjct: 396  PKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEE 455

Query: 433  TSVPPPPAVGRMYPPRSPKSAAPAP----ISASCPEPPIGSAVPTSSASIPVTSSVSDPG 488
            +   PPP   R+ PP     A+P P    +S    E P+      S  S P  SS   P 
Sbjct: 456  SPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSP- 514

Query: 489  VGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKF 548
                SP SP     P+   E     P    E   L+      P  +        EEL   
Sbjct: 515  -LEESPLSPPEESPPSPALETPLSPPP---EASPLS------PPFEESPLSPPPEELPTS 564

Query: 549  GAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGL--------LTSEPMGSPVSSKT 600
                  + S  PE S    PP   +E P     E   L        L+  P  SP+S   
Sbjct: 565  PPPEASRLSPPPEESPMSPPP---EESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPP 621

Query: 601  ES--VSDKEDKPPLAPSGGTEGPEQPPP--------PCPSQTGSPPVGLIKGEDKDEGPV 650
            E+  +S   +  P++P    E P  PPP        P  S+   PP         +E P 
Sbjct: 622  EASRLSPPPEDSPMSPP-PEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPT 680

Query: 651  AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGL-YSPQ 709
            +   + S L+P   E +PT P         +P SP P   S  S+P+  +    L   PQ
Sbjct: 681  SPPPEASRLSP-PPEDSPTSP-----PPEDSPASPPPE-DSLMSLPLEESPLLPLPEEPQ 733

Query: 710  YISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQH-QPASAPPMM 768
                    H+ P  + P + P P               +  L PQ  + H  P    P +
Sbjct: 734  LCPRSEGPHLSPRPEEPHLSPRP--------------EEPHLSPQAEEPHLSPQPEEPCL 779

Query: 769  QAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQP-MAHYPSQPVFAPMLQS------- 820
               A    P ++      ++   P++    P   +P ++  P +P  +P  +        
Sbjct: 780  --CAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQS 837

Query: 821  -----NPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQP 875
                 +PR   S   P+       P  P  E+P  +       +  P     L     +P
Sbjct: 838  EEPCLSPRPEESHLSPEL---EKPPLSPRPEKPPEEPGQCPAPEELP-----LFPPPGEP 889

Query: 876  ATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQP--QQNLYHPGALTGTPPSLPP----- 928
            + +P   +P        P+     + P   SG+P     L  P  L   PP L P     
Sbjct: 890  SLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPL---PPPLSPIITAA 946

Query: 929  GPSAQSPQSSFPQPAAVYAIHHQQLPHGF----TNMAHVTQAHVQTGITAAP---PPHPG 981
             P A SP      P         + P       T ++   +A+        P   PP PG
Sbjct: 947  APPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPG 1006

Query: 982  APHPPQVMLLH---PPQ-----SHGGPPQGAVP-QSGVPALSASTPSPYPYIG------- 1025
            +P  P   +L    PPQ      H   PQ + P Q   PAL  S PSP   IG       
Sbjct: 1007 SPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSD 1066

Query: 1026 ----HPQGEQPGQAPGFPGGADDRIPPLPPP 1052
                H    +    P  P        PLP P
Sbjct: 1067 EAELHEMETEKVSEPECPALEPSATSPLPSP 1097



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 141/594 (23%), Positives = 202/594 (34%), Gaps = 98/594 (16%)

Query: 422  LSSPSNRPSGETSVPPPP-AVGRMYPPRSP-----KSAAPAPISASCP---EPPIGSAVP 472
            ++  ++RP+    +PP P A+G   P  +P         PA +S S     +PP GS   
Sbjct: 2093 IARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPG 2152

Query: 473  TSSAS---------IPVTSSVSDP-GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQE 522
              S           +P      DP G+    P  P+   AP       +   G   +P  
Sbjct: 2153 PDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPT-GAPAQPPM 2211

Query: 523  LARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRI----LKEEPK- 577
            L   A   PG        Q  E             S+P+  L P  P +    + E P  
Sbjct: 2212 LG--ASSRPGAG------QPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGV 2263

Query: 578  GKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPV 637
            G  K  + LL+  P G   S K   V  KE+    +PS G        PP      SP  
Sbjct: 2264 GGGKASEPLLSPPPFGE--SRKALEVK-KEELGASSPSYG--------PPNLGFVDSPSS 2312

Query: 638  GLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPV 697
            G   G  + + P    V K+ L P A +  P  P L +      P  P P     PS P 
Sbjct: 2313 GTHLGGLELKTP---DVFKAPLTPRASQVEPQSPGLGLR-----PQEPPPAQALAPSPP- 2363

Query: 698  LTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQ---GKYRGAKGSLPPQ 754
                   ++ P   SY       P    PQ  P     ++P +      +     S P  
Sbjct: 2364 ---SHPDIFRPG--SYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPAS-PQS 2417

Query: 755  RSDQHQPASAPPMMQAAAAAGPPLVAATP-YSSYIPYNPQQFPGQPAMMQPMA--HYPSQ 811
            +S    P +  P+   A    P     TP + S  PY+    P +P    P A  H P +
Sbjct: 2418 QSSSQSPLTPRPLSAEAFCPSP----VTPRFQSPDPYSRP--PSRPQSRDPFAPLHKPPR 2471

Query: 812  PVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAE--------QPTPQALYATVHQSYPH 863
            P   P +      L   S       ++ P  P+ E        QP P  + +    ++  
Sbjct: 2472 PQ-PPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQP-PNFVRSPGTGAFVG 2529

Query: 864  HATQLHAHQPQPATTPTGSQPQSQHAAPSP--VQHQAGQAPHLGSGQPQQNLYHPGALTG 921
              + +    PQ    P+   P  Q   P P  +    G  P LG  +PQ   Y       
Sbjct: 2530 TPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLG--KPQSTNYTVATGNF 2587

Query: 922  TPPSLPPGPSAQS-----------PQSSFPQPAAVYAIHHQQLPHGFTNMAHVT 964
             P   P GPS+ S           P S  P PA   ++ +  L HG +  + +T
Sbjct: 2588 HPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPY--LSHGASQRSGIT 2639



 Score = 53.9 bits (128), Expect = 8e-07
 Identities = 162/801 (20%), Positives = 262/801 (32%), Gaps = 142/801 (17%)

Query: 308  QYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIP-----LPQRVREGPRG 362
            +YR +   +    + ++++HSAV      +    L    G+ +P      PQ    G  G
Sbjct: 3594 EYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAG 3653

Query: 363  GVRCSSSRGGRPGLSSLP-----------------------PRG---PHHLDNSSPGPGS 396
            G+R +      PG    P                       P G   P +L   S GP S
Sbjct: 3654 GLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDS 3713

Query: 397  ---EARGINGGPSRMS-----------PKAQRPLRGAKTLSSPSNR-PSGETSVPPPPAV 441
               + R +     RM             + Q+ L G   +     + P  +T+    P  
Sbjct: 3714 RLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKP 3773

Query: 442  GRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISL 501
              + PP S +      +S   P+ P G   P   A +           G++ P  P   +
Sbjct: 3774 QGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVL------QQQHPGALGPQGPHRQV 3827

Query: 502  APTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPS---- 557
              T  + LS+ +    L  Q    +  ++   Q +Q++ Q ++         LQ S    
Sbjct: 3828 LMTQSRVLSSPQ----LAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSH 3883

Query: 558  -SSPENSLDPFPP-RILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPS 615
               P+ S  P    + L+++ + ++++       + +      + + +  ++ +  L   
Sbjct: 3884 SGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQ 3943

Query: 616  GGTE----------GPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKE 665
               +            +Q       Q     +GL+        P  +Q ++  L P    
Sbjct: 3944 QQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGM-- 4001

Query: 666  FNPTKPLL--------------------SVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGL 705
              P KPL                     +V+ + S+  + GP TH    + + T  +S  
Sbjct: 4002 --PAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMA 4059

Query: 706  YSPQYISYIPQIHMGPAVQAPQMYPYPVSNSV--------PGQQGK-----YRGAKGSLP 752
              P  +   P +     +   Q  P P  +S+        PGQQ +     +    GS  
Sbjct: 4060 TEPGEVK--PSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHG 4117

Query: 753  PQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHY--PS 810
               S     AS+ P + A      P V+       +  N    P QP + +PM +   P 
Sbjct: 4118 QLGSGSSSEASSVPHLLAQ-----PSVSLGDQPGSMTQNLLG-PQQPMLERPMQNNTGPQ 4171

Query: 811  QPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHA 870
             P   P+LQS   +   G  P      +  Q   A+ P  + L     Q       Q   
Sbjct: 4172 PPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQL 4231

Query: 871  HQPQPAT-TPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPG 929
             Q Q    TP   +P +Q    SP+Q   G  P LG          PG  TG    L  G
Sbjct: 4232 QQSQAVRQTPPYQEPGTQ---TSPLQGLLGCQPQLGG--------FPGPQTGPLQELGAG 4280

Query: 930  PSAQSPQ---------SSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAA-PPPH 979
            P  Q P          S+ P    V+       P      + +     Q    A  PP H
Sbjct: 4281 PRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTH 4340

Query: 980  PGAPHPPQVMLLHPPQSHGGP 1000
            PG P  PQ   L PP     P
Sbjct: 4341 PGTP-KPQGPTLEPPPGRVSP 4360



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 112/505 (22%), Positives = 157/505 (31%), Gaps = 108/505 (21%)

Query: 341  SLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPH--------------- 385
            SL   E   +PLP+  +  PR      S R   P LS  P   PH               
Sbjct: 717  SLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEE-PHLSPQAEEPHLSPQPE 775

Query: 386  -----------HLDNSSPGP--GSEARGINGGPS----RMSPKAQRPLRGAKTLSSPSNR 428
                       HL   + GP    +   ++  P      +SP  + P    +   S  + 
Sbjct: 776  EPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSP 835

Query: 429  PSGETSVPPPPAVGRM-----YPPRSPKSAAPAPISASCPEPPIGSAVP----TSSASIP 479
             S E  + P P    +      PP SP+   P      CP P      P     S + + 
Sbjct: 836  QSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLL 895

Query: 480  VTSSVSDPGVGSISPASPKISLAPTDVKELSTK-EPGRTLEPQELARIAGKVPGLQNEQK 538
               ++S+PG   +SP   ++ L+P+    LS +  P   L P     I    P       
Sbjct: 896  GEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPP------ 949

Query: 539  RFQLEELRKFGAQFKLQPSSSPENSL--------------------DPFPPRILKEEPKG 578
               L  L +    F  +  S PE+ L                    +P PP IL   P  
Sbjct: 950  --ALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGS 1007

Query: 579  KEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSP--P 636
                   +L  EP+    S   +     ++ PP   S         PP  P    SP  P
Sbjct: 1008 PVGPASPIL-MEPLPPQCSPLLQHSLVPQNSPPSQCS---------PPALPLSVPSPLSP 1057

Query: 637  VGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNP--TKPLLSVNKSTSTPT-SPGPRTHSTP 693
            +G + G   DE  + E   +    P      P  T PL S     S P  SP P      
Sbjct: 1058 IGKVVGV-SDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFS 1116

Query: 694  SIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQ-QGKYRGAKGSLP 752
             +   TA   G                  + AP   P P     PG    + +G+   L 
Sbjct: 1117 GLGEDTAPLDG------------------IDAPGSQPEP--GQTPGSLASELKGSPVLLD 1156

Query: 753  PQRSDQHQPASAPPMMQAAAAAGPP 777
            P+      P    P  +  A  G P
Sbjct: 1157 PEELAPVTPMEVYPECKQTAGQGSP 1181



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 162/717 (22%), Positives = 240/717 (33%), Gaps = 148/717 (20%)

Query: 377  SSLPPRGPHHL---DNSSPGP---GSEARGINGGPSRMSPKAQRPLRGAKTLS-SPSNRP 429
            +S P  GP +L   D+ S G    G E +  +   + ++P+A +    +  L   P   P
Sbjct: 2294 ASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPP 2353

Query: 430  SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGV 489
              +   P PP+   ++ P S       P     P+PP     P S  ++P  S  SDP  
Sbjct: 2354 PAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPP----PPESCCALPPRSLPSDPF- 2408

Query: 490  GSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFG 549
             S  PASP+         + S++ P   L P+ L+  A     +     RFQ  +     
Sbjct: 2409 -SRVPASPQ--------SQSSSQSP---LTPRPLSAEAFCPSPVT---PRFQSPDPYS-- 2451

Query: 550  AQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD---GLLTSEPMGS---PVSSKTESV 603
                 +P S P+ S DPF P  L + P+ +  EV    G L    +G+   P +      
Sbjct: 2452 -----RPPSRPQ-SRDPFAP--LHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPA 2503

Query: 604  SDKEDKPPLAP---------SGGTEGPEQP--------------PPPCPSQTGSPPVGLI 640
             +   K P            +G   G   P               PP P     PP G+ 
Sbjct: 2504 GELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGI- 2562

Query: 641  KGEDKDEGPVAEQVKKSTLNPNAKEFNPT-KPLLSVNKSTST--------PTSPGPRTHS 691
                   GP   + + +        F+P+  PL   + ST          P S  P    
Sbjct: 2563 -NSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAP 2621

Query: 692  TPSIPVLTAG---QSGLYSPQYISYIPQIHMG--------PAVQAPQMYPYPVS------ 734
              S+P L+ G   +SG+ SP      P   MG        P  Q P M     +      
Sbjct: 2622 DGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQR 2681

Query: 735  ----------------NSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPL 778
                            N++  ++     A G++ P  S   +P+S  P  +  +    P 
Sbjct: 2682 QRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSS--PAFEQLSRGQTPF 2739

Query: 779  VAATPYSSYIPYNPQQFPGQ---PAMM--QPMAHYPSQPVFAPMLQSNPRMLTSGSHPQA 833
                  SS +   P +  G    P           P  P     +  N R L  GS  QA
Sbjct: 2740 AGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGS--QA 2797

Query: 834  IVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQ-SQHAAPS 892
                +   YP +  P  Q       Q     AT +       A  P+   P+  + A  S
Sbjct: 2798 FYQRAP--YPGS-LPLQQQQQQLWQQQQATAATSMRF--AMSARFPSTPGPELGRQALGS 2852

Query: 893  PVQHQAGQAPHLGSGQPQQNLYHPGALT--------GTPPSLPPGPSAQSPQSSFPQPAA 944
            P+   + + P  G G+P      P            G  P   P P    PQ   P+   
Sbjct: 2853 PLAGISTRLP--GPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQR--PRFYP 2908

Query: 945  VYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQV-MLLHPPQSHGGP 1000
            V    H+  P G   +A          ++  PP  P AP  P++   LHP     GP
Sbjct: 2909 VSEDPHRLAPEGLRGLA----------VSGLPPQKPSAPPAPELNNSLHPTPHTKGP 2955



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 88/358 (24%), Positives = 135/358 (37%), Gaps = 61/358 (17%)

Query: 361  RGGVRCSSSRGGRPGLSSLP---------PRGPHHLDNSSPGPGSEARGINGGPSRMSP- 410
            +G + C    GG PG  + P         P+GP  L      PG+ + G   GP   +P 
Sbjct: 4254 QGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAP---PGALSTGPVLGPVHPTPP 4310

Query: 411  --KAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIG 468
                Q P R ++ L SPS++   E  +PP         P +PK   P        EPP G
Sbjct: 4311 PSSPQEPKRPSQ-LPSPSSQLPTEAQLPPT-------HPGTPKPQGPT------LEPPPG 4356

Query: 469  SAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAG 528
               P   A+  +  ++   G+G   P  P  +LA T   E S+  PG       L ++ G
Sbjct: 4357 RVSP---AAAQLADTLFSKGLG---PWDPPDNLAETQKPEQSSLVPG------HLDQVNG 4404

Query: 529  KV--PGLQNEQKRFQLEELRKFGAQ-FKLQPSSSP------ENSLDPFPPR------ILK 573
            +V     Q   K+   EE    GAQ  K + +  P       N L    PR      +L+
Sbjct: 4405 QVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQ 4464

Query: 574  EEPKGKEKEVDGLLTSEPMGSPVSSKTES-VSDKEDKPPLAPSGGTEG----PEQPPPPC 628
            +  + K  ++     SE + + ++   +S ++  E K    PS   +     P  P P  
Sbjct: 4465 KLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPLTPKPKR 4524

Query: 629  PSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPG 686
              +     V   K   K++G  A +     L         T+P ++ N S   P   G
Sbjct: 4525 VQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSG 4582



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 90/379 (23%), Positives = 122/379 (32%), Gaps = 62/379 (16%)

Query: 721  PAVQAPQMY---PYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPP 777
            P   AP ++   P   +       G  +   GS+P   S        PP + A   +  P
Sbjct: 2117 PPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDP 2176

Query: 778  LVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQA---- 833
               A  Y    P  P+ FP  P    P   YPS P  AP   + P ML + S P A    
Sbjct: 2177 FGLAPAY----PLEPR-FPTAPPTYPP---YPS-PTGAP---AQPPMLGASSRPGAGQPG 2224

Query: 834  IVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLH-------AHQPQPATTPTGSQPQS 886
               ++ P  P  +  TP         S  + A           A +P  +  P G   ++
Sbjct: 2225 EFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKA 2284

Query: 887  QHAAPSPVQHQAGQ--APHLGSGQPQQNLYHPGALTGTPPS-----LPPGPSAQSPQS-- 937
                   +   +     P+LG      +  H G L    P      L P  S   PQS  
Sbjct: 2285 LEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPG 2344

Query: 938  -----SFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLH 992
                   P PA   A      P  F   ++ T  + Q  +T  P P P     P+     
Sbjct: 2345 LGLRPQEPPPAQALAPSPPSHPDIFRPGSY-TDPYAQPPLTPRPQPPP-----PESCCAL 2398

Query: 993  PPQSHGGPPQGAVPQSGVPALSASTP-----------SPYPYIGHPQGEQP-GQAPGFPG 1040
            PP+S    P   VP S     S+ +P            P P     Q   P  + P  P 
Sbjct: 2399 PPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQ 2458

Query: 1041 GADD----RIPPLPPPGEL 1055
              D       PP P P E+
Sbjct: 2459 SRDPFAPLHKPPRPQPPEV 2477



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 33/112 (29%), Positives = 43/112 (38%), Gaps = 22/112 (19%)

Query: 1    MLKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
            +L  + LQQ    +Q PP Q+      PG  + P  GL G        PGP        G
Sbjct: 4225 LLMQRQLQQSQAVRQTPPYQE------PGTQTSPLQGLLGCQPQLGGFPGPQT------G 4272

Query: 61   PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
            P+   G+G          P+P  P +    PGA + G   G      PP SP
Sbjct: 4273 PLQELGAG----------PRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSP 4314



 Score = 34.3 bits (77), Expect = 0.64
 Identities = 32/120 (26%), Positives = 43/120 (35%), Gaps = 10/120 (8%)

Query: 2   LKPQPLQQPSQ--PQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCL 59
           L+  PL  P +  P  PPP     +       SPP    P P   +  P  PP  ASP  
Sbjct: 489 LEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALET--PLSPPPEASPLS 546

Query: 60  GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS----PVFE 115
            P     S L    E +    PP   +    P  + +     +S    PP++    P FE
Sbjct: 547 PPFEE--SPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFE 604



 Score = 33.9 bits (76), Expect = 0.84
 Identities = 30/97 (30%), Positives = 42/97 (43%), Gaps = 21/97 (21%)

Query: 2    LKPQ-PLQQPSQPQQPPPTQQAVARRPP--GGTSPPNGGLPGPLATSAAPPG----PPAA 54
            L+P+ P   P+ P  P PT      +PP  G +S P  G PG   T+  PPG     P+ 
Sbjct: 2185 LEPRFPTAPPTYPPYPSPT--GAPAQPPMLGASSRPGAGQPGEFHTT--PPGTPRHQPST 2240

Query: 55   ASPCLGP----------VAAAGSGLRRGAEGILAPQP 81
              P L P            + G G  + +E +L+P P
Sbjct: 2241 PDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPP 2277



 Score = 33.9 bits (76), Expect = 0.84
 Identities = 85/391 (21%), Positives = 128/391 (32%), Gaps = 66/391 (16%)

Query: 561  ENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEG 620
            +N++DP    +  E  +G      G     P+    + ++ +    E KP L+       
Sbjct: 4026 QNTVDP---AVSSEATEGPSTHQGG-----PLAIGTTPESMATEPGEVKPSLSGDSQLLL 4077

Query: 621  PEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQV---KKSTLNPNAKEFNPTKPLLSVNK 677
             +  P P PS     P   + G+ + +  +           L   +     + P L    
Sbjct: 4078 VQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQP 4137

Query: 678  STSTPTSPGPRTHST--PSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSN 735
            S S    PG  T +   P  P+L         PQ          GP +Q+ Q  P     
Sbjct: 4138 SVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQ------PPKPGPVLQSGQGLPGVGIM 4191

Query: 736  SVPGQ-QGKYRGAKGSLP------PQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYI 788
               GQ + + +G     P      PQ+  Q Q       +Q + A     V  TP     
Sbjct: 4192 PTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQA-----VRQTP----- 4241

Query: 789  PYNPQQFPG-QPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQ 847
               P Q PG Q + +Q +     Q    P  Q+ P         Q + +   PQ P    
Sbjct: 4242 ---PYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPL--------QELGAGPRPQGPP-RL 4289

Query: 848  PTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSG 907
            P P    +T     P H T        P ++P   +  SQ  +PS       Q P     
Sbjct: 4290 PAPPGALSTGPVLGPVHPTP-------PPSSPQEPKRPSQLPSPSSQLPTEAQLPPT--- 4339

Query: 908  QPQQNLYHPGALTGTPPSLPPGPSAQSPQSS 938
                   HPG      P+L P P   SP ++
Sbjct: 4340 -------HPGTPKPQGPTLEPPPGRVSPAAA 4363



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 34/125 (27%), Positives = 50/125 (40%), Gaps = 16/125 (12%)

Query: 2   LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
           L P+P + P +P Q P  ++     PPG   P    L G  A S   PG P   SP    
Sbjct: 860 LSPRPEKPPEEPGQCPAPEELPLFPPPG--EPSLSPLLGEPALS--EPGEP-PLSPLPEE 914

Query: 62  VAAAGSGLRRGAEGILAPQPPPPQ-----QHQERPGAAAIG------SARGQSTGKGPPQ 110
           +  + SG    +  ++ P P PP           P  + +G       A+G S  + P  
Sbjct: 915 LPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLA 974

Query: 111 SPVFE 115
           +P+ E
Sbjct: 975 APILE 979



 Score = 33.5 bits (75), Expect = 1.1
 Identities = 23/75 (30%), Positives = 28/75 (37%), Gaps = 4/75 (5%)

Query: 974  AAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPG 1033
            +APPP    P PP   L   P S    P   +P    P      PSP P    P+  +P 
Sbjct: 4907 SAPPPEE--PSPPPSPLAPSPASPPTEPLVELPTE--PLAEPPVPSPLPLASSPESARPK 4962

Query: 1034 QAPGFPGGADDRIPP 1048
                 P   +D  PP
Sbjct: 4963 PRARPPEEGEDSRPP 4977



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 42/143 (29%), Positives = 54/143 (37%), Gaps = 9/143 (6%)

Query: 923  PPSLPPGPSAQSPQSSFPQ-PAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPP-PHP 980
            P    PGP   SP   F + P  V A    Q P G    A+  +    T     PP P P
Sbjct: 2146 PAGSVPGPD--SPGELFLKLPPQVPAQVPSQDPFGLAP-AYPLEPRFPTAPPTYPPYPSP 2202

Query: 981  -GAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPY--PYIGHPQGEQPGQAPG 1037
             GAP  P ++        G P +      G P    STP P+  P           ++PG
Sbjct: 2203 TGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPG 2262

Query: 1038 FPGG-ADDRIPPLPPPGELKIVL 1059
              GG A + +   PP GE +  L
Sbjct: 2263 VGGGKASEPLLSPPPFGESRKAL 2285



 Score = 32.0 bits (71), Expect = 3.2
 Identities = 38/130 (29%), Positives = 46/130 (35%), Gaps = 28/130 (21%)

Query: 1    MLKPQPLQQPSQPQQPPP-------TQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPA 53
            +++PQP  QPS  Q  PP        QQ       GG S    G  G  ++S A   P  
Sbjct: 4077 LVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGS---HGQLGSGSSSEASSVPHL 4133

Query: 54   AASPCLGPVAAAGS-----------GLRRGAEGILAPQPPPP----QQHQERPGAA---A 95
             A P +      GS            L R  +    PQPP P    Q  Q  PG      
Sbjct: 4134 LAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPT 4193

Query: 96   IGSARGQSTG 105
            +G  R Q  G
Sbjct: 4194 VGQLRAQLQG 4203



 Score = 31.6 bits (70), Expect = 4.2
 Identities = 22/74 (29%), Positives = 27/74 (36%), Gaps = 1/74 (1%)

Query: 16   PPPTQQAVARRPPGGTSPPNGGLPG-PLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAE 74
            PP     V  + P G +P     P  P A    PP P    +P   P+  A S    G  
Sbjct: 2164 PPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQP 2223

Query: 75   GILAPQPPPPQQHQ 88
            G     PP   +HQ
Sbjct: 2224 GEFHTTPPGTPRHQ 2237



 Score = 31.2 bits (69), Expect = 5.4
 Identities = 34/124 (27%), Positives = 44/124 (35%), Gaps = 23/124 (18%)

Query: 3    KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPV 62
            K Q  QQ  Q QQ    Q A+ ++   G        PG     A  P P     P     
Sbjct: 3733 KLQQQQQQQQQQQHLLGQVAIQQQQQQG--------PGVQTNQALGPKPQGLMPPS---- 3780

Query: 63   AAAGSGLRRGAEGILAPQ--PPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVFEGVYNN 120
                       +G+L  Q  P PPQ  Q   G A +   + Q  G   PQ P  + +   
Sbjct: 3781 ---------SHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQ 3831

Query: 121  SRML 124
            SR+L
Sbjct: 3832 SRVL 3835



 Score = 31.2 bits (69), Expect = 5.4
 Identities = 31/112 (27%), Positives = 42/112 (37%), Gaps = 22/112 (19%)

Query: 834  IVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSP 893
            I+S    + P+ E PT          SY ++ + L   Q   A  P    P     APSP
Sbjct: 4875 ILSLLKQESPAPEPPT--------QHSYTYNVSNLDVRQLS-APPPEEPSPPPSPLAPSP 4925

Query: 894  VQHQAGQAPHLGSGQPQQNLYH-PGALTGTPPSLPPGPSAQSPQSSFPQPAA 944
                        +  P + L   P      PP   P P A SP+S+ P+P A
Sbjct: 4926 ------------ASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRA 4965



 Score = 30.4 bits (67), Expect = 9.2
 Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 11/93 (11%)

Query: 5   QPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAA 64
           +PL++   P  PPP +  ++  PP  +SP +     PL+     P  PA  +P L P   
Sbjct: 487 RPLEE--SPLSPPPEESPLS--PPPESSPFSPLEESPLSPPEESPPSPALETP-LSPPPE 541

Query: 65  AGSGLRRGAEGILAPQP------PPPQQHQERP 91
           A        E  L+P P      PPP+  +  P
Sbjct: 542 ASPLSPPFEESPLSPPPEELPTSPPPEASRLSP 574



 Score = 30.4 bits (67), Expect = 9.2
 Identities = 83/369 (22%), Positives = 113/369 (30%), Gaps = 80/369 (21%)

Query: 740  QQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQP 799
            QQ + +   G +  Q+  Q  P      +Q   A GP      P SS+     QQ   QP
Sbjct: 3740 QQQQQQHLLGQVAIQQQQQQGPG-----VQTNQALGPKPQGLMPPSSHQGLLVQQLSPQP 3794

Query: 800  AMMQPMAHYPSQPVFAPMLQSNPRML-TSGSHPQAIVSSS----TPQYPSAEQPTPQALY 854
                     P+Q   A + Q +P  L   G H Q +++ S    +PQ     Q       
Sbjct: 3795 PQGPQGMLGPAQ--VAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRL 3852

Query: 855  ATVHQ----------------SYPHHATQLHAHQPQPATTPTGS--------QPQSQHAA 890
             T  Q                S+   +   H+ QP+ +  P GS        Q Q Q   
Sbjct: 3853 VTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQL 3912

Query: 891  PSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHH 950
                Q Q  Q   L   Q QQ              L      Q  Q    Q    +    
Sbjct: 3913 QQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQ--QQQQQLQQQQQQQQQQFQQQQ 3970

Query: 951  QQLPHGFTNMAHV---------TQAHVQTGITAAPPPH---PGAPHPPQVM--------- 989
            QQ   G  N +            Q  +  G+ A P  H   PGA  P  ++         
Sbjct: 3971 QQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVD 4030

Query: 990  ------LLHPPQSHGGPPQ--GAVPQSGV-------PALSAST------PSPYPYIGHPQ 1028
                      P +H G P   G  P+S         P+LS  +      P P P     Q
Sbjct: 4031 PAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQ 4090

Query: 1029 GEQPGQAPG 1037
             + P + PG
Sbjct: 4091 LQPPLRLPG 4099


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
          Length = 816

 Score = 97.1 bits (240), Expect = 8e-20
 Identities = 189/782 (24%), Positives = 264/782 (33%), Gaps = 148/782 (18%)

Query: 357  REGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGING-GPSRMSPKAQRP 415
            R+  + G    +     PGL  L PR P       P   +  R +   G     P A+R 
Sbjct: 5    RDKAKAGAAARTPAARAPGL--LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERA 62

Query: 416  LRGAKTLSSPSNRP-SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTS 474
              G    + P + P +G T    PPA GR       K+ +P P+S+  P    G+  P  
Sbjct: 63   -GGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSS--PGRASGTTRP-- 117

Query: 475  SASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELAR-IAGKVPGL 533
                           G +     +IS   T  +  +T+ P R+       R  +G  PG 
Sbjct: 118  ---------------GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGT 162

Query: 534  QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593
             +          R  G +  L     P  S  P PP    E P+          T+EP  
Sbjct: 163  PSPA---MARRSRAAGTEVGLP---RPAPSARPRPPT---EGPRKSVSSASEHSTTEP-- 211

Query: 594  SPVSSKTESVSDKEDKPPLAPSGGTEGP-EQPPPPCPSQTGSPPVGLIKGEDKDEGPVAE 652
            SP + +  S      +P       +  P   P    PS  G+P       + K +G   +
Sbjct: 212  SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG--LQ 269

Query: 653  QVKKSTLNPNAKEFNPTK-PLLSVNKSTSTPTSPG-----PRTHSTPSIPVLTAGQS--G 704
             ++   + P  K+  P   PL S   +T +P++P      P   + PS P     Q+   
Sbjct: 270  ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTS 329

Query: 705  LYSPQYI---SYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQP 761
            L SP      S++P   + P    P   P  ++                LPP ++    P
Sbjct: 330  LGSPTLQATHSFLPSPPLSPLATPPPQAPPALA----------------LPPLQAPPSPP 373

Query: 762  ASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSN 821
            AS PP+   A  +     A   +    P++P   P   A   P A  P  P   P  Q+ 
Sbjct: 374  AS-PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 432

Query: 822  PRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTG 881
            P +            +S P  PSA  P PQA         P  A  L   +P P   P  
Sbjct: 433  PSLAAPPLQVPPSPPASPPMSPSA-TPPPQA-------PPPLAAPPLQLAKPPPQAPPAL 484

Query: 882  SQPQSQHAAPSPVQHQAGQAPH----------LGSGQPQQNLYHPGALTGTPPSLPPGPS 931
            + P  Q A PSP     GQAP           L +  PQ        L   PPS P  P+
Sbjct: 485  ATPPLQ-ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 543

Query: 932  AQSPQ--------SSFPQPAAVYAIHHQQLP---------------HGFTNMAHVTQAHV 968
             Q+P+        +S   P    A+     P                G ++ A  T   +
Sbjct: 544  LQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL 603

Query: 969  -------QTGITAAPPP-------HPGA----PHPPQVM-------LLHPPQSHGGPPQG 1003
                   + G  A+PPP       HP A    P PP          L  PP +  G   G
Sbjct: 604  RGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADG 663

Query: 1004 AV-------PQSGVPALSASTPSPYPYIGHPQGEQPGQ-APGFPGGADDRIPPLPPPGEL 1055
                     P+S  PA  A  P P P      G   G+ A G   GA  R P     GEL
Sbjct: 664  LCTIYETEGPESATPAPGALDPGPSP------GTSGGKAAAGAGAGASSRSPKQARLGEL 717

Query: 1056 KI 1057
             +
Sbjct: 718  PL 719



 Score = 78.6 bits (192), Expect = 3e-14
 Identities = 131/527 (24%), Positives = 180/527 (34%), Gaps = 70/527 (13%)

Query: 585  GLLTSEPMGSP--------VSSKTESVSDKEDKPPLAPSGGTEG----PEQPPPPCPSQT 632
            GLLT  P GSP         + +    +    + PLA   G  G    PE  P   P++T
Sbjct: 23   GLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRT 82

Query: 633  GSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKP----LLSVNKSTSTPTSPGPR 688
              PP    +GE     P A+      ++   +    T+P       +  S     + G  
Sbjct: 83   SRPPASG-RGE---RAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKA 138

Query: 689  THSTPSIPVLTAGQS--------GLYSPQYI--SYIPQIHMGPAVQAPQMYPYPVSNSVP 738
            T + P    L+AG          G  SP     S      +G    AP   P P +   P
Sbjct: 139  TEA-PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG-P 196

Query: 739  GQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQ----- 793
             +         +  P  + + +P++   + + A+ +     +ATP SS     P      
Sbjct: 197  RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS--SATPLSSPARSGPSARGTP 254

Query: 794  QFPGQPAMMQPMAHYPSQP--VFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQ---- 847
            + P  P+  +P      +P  V  P   + P +    S P A  S S P  PSA      
Sbjct: 255  RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQT 314

Query: 848  -PTPQAL---YATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPH 903
             P+P A     AT     P      H+  P P  +P  + P     A +    QA  +P 
Sbjct: 315  LPSPPATPPSQATTSLGSPT-LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP 373

Query: 904  -------LGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHG 956
                   L +  PQ        L   P S PP P  Q+P   F  PA+         P  
Sbjct: 374  ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP---FSPPASPPVSPSATPPSQ 430

Query: 957  FTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVM--LLHPPQSHGGPPQGAVPQSGVPALS 1014
                       V     A+PP  P A  PPQ    L  PP     PP  A P    P L 
Sbjct: 431  APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQ 490

Query: 1015 ASTPSPYPYIGHPQGEQPGQAPGFPGGADDRIPPLPPPGELKIVLAA 1061
            A    P  +        PGQAP  P  +    P   PP +   VLAA
Sbjct: 491  ALPSPPASF--------PGQAPFSPSASLPMSPLATPPPQAPPVLAA 529



 Score = 39.7 bits (91), Expect = 0.015
 Identities = 33/123 (26%), Positives = 44/123 (35%), Gaps = 22/123 (17%)

Query: 6   PLQQPSQPQQPPPTQQAVARRPPGGTS------------PPNGGLPGPLATSAAPPGPPA 53
           PLQ P  P   PP        P    +            PP+  +  P +  A+PP  P+
Sbjct: 365 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 424

Query: 54  AASPCLGPVAAAGSGLRRGAEGILAPQPP--PPQQHQERPGAAAIG--SARGQSTGKGPP 109
           A  P   P + A   L+      + P PP  PP      P   A    +A      K PP
Sbjct: 425 ATPPSQAPPSLAAPPLQ------VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 478

Query: 110 QSP 112
           Q+P
Sbjct: 479 QAP 481



 Score = 38.1 bits (87), Expect = 0.044
 Identities = 35/110 (31%), Positives = 46/110 (41%), Gaps = 22/110 (20%)

Query: 10  PSQPQQPPPTQQAVARRPPGGTSPPNGGLP--GPLATS-AAPPGPPAAASPCLGPVAAAG 66
           P+ P QP P +   A RPP  T P     P  GPL++S  A P P A  SP   P     
Sbjct: 257 PAHPSQPKP-KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPP----- 310

Query: 67  SGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK---GPPQSPV 113
                  + + +P   PP Q        ++GS   Q+T      PP SP+
Sbjct: 311 -----SLQTLPSPPATPPSQ-----ATTSLGSPTLQATHSFLPSPPLSPL 350



 Score = 37.0 bits (84), Expect = 0.099
 Identities = 34/122 (27%), Positives = 48/122 (39%), Gaps = 15/122 (12%)

Query: 3   KPQPLQQPSQPQQPPPTQQAVAR---------RPPGGTSPPNGGLPGPLATSAAPPG-PP 52
           KP+ LQ    PQ  PP + A              P  ++PP+   P  L T  +PP  PP
Sbjct: 264 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPP 323

Query: 53  AAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARG-QSTGKGPPQS 111
           + A+  LG      +     +  +     PPPQ     P A A+   +   S    PP S
Sbjct: 324 SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ----APPALALPPLQAPPSPPASPPLS 379

Query: 112 PV 113
           P+
Sbjct: 380 PL 381



 Score = 37.0 bits (84), Expect = 0.099
 Identities = 39/122 (31%), Positives = 48/122 (39%), Gaps = 30/122 (24%)

Query: 13  PQQPP--PTQQAVARRPPGGTSPPNGGLPGP---LATSAAPPGPP--AAASPCLGPVAAA 65
           P  PP  PT QA  RRPP  T  P+  + GP   LA +  PP PP  + +S   GP  A 
Sbjct: 535 PPSPPASPTLQA-PRRPP--TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 591

Query: 66  GS-----------GLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVF 114
            S           G   G EG  A  PPP          A + +    +  +GP     F
Sbjct: 592 HSSSATSTPEELRGYDSGPEGGAAASPPPD---------AELAACHPAAWSRGPAPPLAF 642

Query: 115 EG 116
            G
Sbjct: 643 RG 644



 Score = 33.9 bits (76), Expect = 0.84
 Identities = 36/125 (28%), Positives = 43/125 (34%), Gaps = 27/125 (21%)

Query: 4   PQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLAT---------SAAPPGPPAA 54
           P PL  P      PP Q      PP   +PP   LP P A+         SA+ P  P A
Sbjct: 463 PPPLAAPPLQLAKPPPQA-----PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 517

Query: 55  ASPCLGPVAAAGSGLRRGAEGILAPQPP--PPQQHQER-----PGAAAIGSARGQSTGKG 107
             P   P   A   L+      + P PP  P  Q   R     P  +  G     +   G
Sbjct: 518 TPPPQAPPVLAAPLLQ------VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 571

Query: 108 PPQSP 112
           PP  P
Sbjct: 572 PPPPP 576



 Score = 33.1 bits (74), Expect = 1.4
 Identities = 39/143 (27%), Positives = 55/143 (38%), Gaps = 34/143 (23%)

Query: 1   MLKPQPLQQPSQPQQPPPTQQ----------AVARRP--------PGGTSPPNGGLPGPL 42
           +L P+P   P  P+ PPP             AV R+P         G T P +    GP 
Sbjct: 24  LLTPRP---PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT 80

Query: 43  ATSAAPPG-----PPAAASPCLGPVAAAG--SGLRR----GAEG--ILAPQPPPPQQHQE 89
            TS  P        P A +   GPV++ G  SG  R    G +G  I A +     +  E
Sbjct: 81  RTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE 140

Query: 90  RPGAAAIGSARGQSTGKGPPQSP 112
            P  +A+ +   + T    P +P
Sbjct: 141 APKRSALSAGARRDTSGPTPGTP 163



 Score = 32.0 bits (71), Expect = 3.2
 Identities = 30/100 (30%), Positives = 36/100 (36%), Gaps = 12/100 (12%)

Query: 10  PSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGL 69
           P  P   PP Q      PP    PP   L  P +  A+PP  P A      P A A   L
Sbjct: 346 PLSPLATPPPQ-----APPALALPP---LQAPPSPPASPPLSPLATPSPQAPNALAVHLL 397

Query: 70  RRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109
               +   +P P PP Q    P A+   S       + PP
Sbjct: 398 ----QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 433



 Score = 31.6 bits (70), Expect = 4.2
 Identities = 33/119 (27%), Positives = 43/119 (36%), Gaps = 21/119 (17%)

Query: 6   PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPG-P---PAAASPCLGP 61
           P+Q P  P   PP   +     P   +PP+   P PL    +PP  P   P+A  P   P
Sbjct: 408 PVQAPFSPPASPPVSPSAT---PPSQAPPSLAAP-PLQVPPSPPASPPMSPSATPPPQAP 463

Query: 62  VAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGP-------PQSPV 113
              A   L+      LA  PP        P   A+ S      G+ P       P SP+
Sbjct: 464 PPLAAPPLQ------LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 516



 Score = 31.6 bits (70), Expect = 4.2
 Identities = 29/91 (31%), Positives = 34/91 (37%), Gaps = 13/91 (14%)

Query: 16  PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEG 75
           PPP  +  A  P   +  P      PLA   AP G P    P  GP +A G       EG
Sbjct: 618 PPPDAELAACHPAAWSRGP----APPLAFRGAP-GAPLPWPPATGPGSADGLCTIYETEG 672

Query: 76  ILAPQPPPPQQHQERPGAAAIGSARGQSTGK 106
                   P+     PGA   G + G S GK
Sbjct: 673 --------PESATPAPGALDPGPSPGTSGGK 695



 Score = 30.4 bits (67), Expect = 9.2
 Identities = 31/126 (24%), Positives = 45/126 (35%), Gaps = 21/126 (16%)

Query: 6   PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGP--------PAAASP 57
           P   P++  +PP + +     P   TSP     PG  A+    PGP         A  + 
Sbjct: 75  PRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPG-RASGTTRPGPLGQKGLRISAEETV 133

Query: 58  CLGPV------AAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIG------SARGQSTG 105
             G        +A  +G RR   G     P P    + R     +G      SAR +   
Sbjct: 134 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 193

Query: 106 KGPPQS 111
           +GP +S
Sbjct: 194 EGPRKS 199


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 855

 Score = 91.7 bits (226), Expect = 3e-18
 Identities = 194/793 (24%), Positives = 262/793 (33%), Gaps = 202/793 (25%)

Query: 357  REGP-RGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRP 415
            R GP R     S +   RP  S    R P    N+SPGP S   G   G +R  P  Q+ 
Sbjct: 76   RAGPTRSAGTSSRNPASRPPASGRGERAPP-AKNTSPGPVSSP-GRASGTTRPGPLGQKG 133

Query: 416  LR---------GAKT-------LSSPSNRP-SGETSVPPPPAVGRMYPPRSPKSAAPAPI 458
            LR         G  T       LS+ + R  SG T   P PA+ R       +   P P 
Sbjct: 134  LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 193

Query: 459  SASCPEPPI-GSAVPTSSASIPVTSSVS-------DPGVGSISPASPKISLAPTDVKELS 510
             ++ P PP  G     SSAS   T+  S         G G   PAS  +S + T +   +
Sbjct: 194  PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253

Query: 511  TKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPR 570
               P         AR   + P   ++ K   L+ LR                     PP+
Sbjct: 254  RSGPS--------ARGTPRAPAHPSQPKPKGLQALR---------------------PPQ 284

Query: 571  ILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPS 630
            +    P+       G L+S P+ +P                 +PS   +   Q PP  P+
Sbjct: 285  VTP--PRKDAAPALGPLSSSPLATP-----------------SPSAALQS--QAPPTLPA 323

Query: 631  QTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTH 690
               S  +            +A  +  +  +P+A     T P        S P +P  +  
Sbjct: 324  TPHSSSLTC---------QLATPLPLAPPSPSAPPSLQTLP--------SPPATPPSQAT 366

Query: 691  STPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGS 750
            ++   P L A  S L SP          + P    P   P  ++                
Sbjct: 367  TSLGSPTLQATHSFLPSPP---------LSPLATPPPQAPPALA---------------- 401

Query: 751  LPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPS 810
            LPP ++    PAS PP+   A  +     A   +    P++P   P   A   P A  P 
Sbjct: 402  LPPLQAPPSPPAS-PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 460

Query: 811  QPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHA 870
             P   P  Q+ P +            +S P  PSA  P PQA         P  A  L  
Sbjct: 461  SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA-TPPPQA-------PPPLAAPPLQL 512

Query: 871  HQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPH----------LGSGQPQQNLYHPGALT 920
             +P P   P  + P  Q A PSP     GQAP           L +  PQ        L 
Sbjct: 513  AKPPPQAPPALATPPLQ-ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL 571

Query: 921  GTPPSLPPGPSAQSPQ--------SSFPQPAAVYAIHHQQLP---------------HGF 957
              PPS P  P+ Q+P+        +S   P    A+     P                G 
Sbjct: 572  QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGH 631

Query: 958  TNMAHVTQAHV-------QTGITAAPPP-------HPGA----PHPPQVM-------LLH 992
            ++ A  T   +       + G  A+PPP       HP A    P PP          L  
Sbjct: 632  SSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPW 691

Query: 993  PPQSHGGPPQGAV-------PQSGVPALSASTPSPYPYIGHPQGEQPGQ-APGFPGGADD 1044
            PP +  G   G         P+S  PA  A  P P P      G   G+ A G   GA  
Sbjct: 692  PPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP------GTSGGKAAAGAGAGASS 745

Query: 1045 RIPPLPPPGELKI 1057
            R P     GEL +
Sbjct: 746  RSPKQARLGELPL 758



 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 156/653 (23%), Positives = 214/653 (32%), Gaps = 127/653 (19%)

Query: 440  AVGRMYPPRSPKSAAPAPISASCPEPPIGSA---VPTSSASI---PVTSSVSDPGVGSIS 493
            A  R    R+P    P P  +  P PP+  A   V  ++ ++   P+       G  +I 
Sbjct: 12   AAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71

Query: 494  PASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFK 553
             ++P+    PT     S++ P     P    R   + P  +N                  
Sbjct: 72   ESAPRAG--PTRSAGTSSRNPAS--RPPASGR-GERAPPAKNTSPG-------------- 112

Query: 554  LQPSSSPENSLDPFPPRILKEEP---KGKEKEVDGLLTSEPMGSPVSS----KTESVSDK 606
              P SSP  +     P  L ++      +E    G  T  P  S +S+     T   +  
Sbjct: 113  --PVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG 170

Query: 607  EDKPPLAPSGGTEGPEQP-PPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKE 665
               P +A      G E   P P PS    PP          EGP     +KS    +A E
Sbjct: 171  TPSPAMARRSRAAGTEVGLPRPAPSARPRPPT---------EGP-----RKSV--SSASE 214

Query: 666  FNPTKPLLSVNKSTSTPTS---PGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722
             + T+P  +  +  S       P  R+ S+ + P+ +  +SG          P     P 
Sbjct: 215  HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG----------PSARGTPR 264

Query: 723  VQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGP----PL 778
              A    P P            +G +   PPQ +        PP   AA A GP    PL
Sbjct: 265  APAHPSQPKP------------KGLQALRPPQVT--------PPRKDAAPALGPLSSSPL 304

Query: 779  VAATPYSSYIPYNPQQFPGQP-------AMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHP 831
               +P ++     P   P  P        +  P+   P  P   P LQ+ P    +    
Sbjct: 305  ATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPS- 363

Query: 832  QAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAP 891
            QA  S  +P   +     P    + +    P     L     Q   +P  S P S  A P
Sbjct: 364  QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATP 423

Query: 892  SPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPP-GPSAQSPQSSFPQPAAVYAIHH 950
            SP Q     A HL           P     +PP+ PP  PSA  P  + P  AA      
Sbjct: 424  SP-QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA------ 476

Query: 951  QQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVM--LLHPPQSHGGPPQGAVPQS 1008
                             V     A+PP  P A  PPQ    L  PP     PP  A P  
Sbjct: 477  -------------PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL 523

Query: 1009 GVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRIPPLPPPGELKIVLAA 1061
              P L A    P  +        PGQAP  P  +    P   PP +   VLAA
Sbjct: 524  ATPPLQALPSPPASF--------PGQAPFSPSASLPMSPLATPPPQAPPVLAA 568



 Score = 39.7 bits (91), Expect = 0.015
 Identities = 33/123 (26%), Positives = 44/123 (35%), Gaps = 22/123 (17%)

Query: 6   PLQQPSQPQQPPPTQQAVARRPPGGTS------------PPNGGLPGPLATSAAPPGPPA 53
           PLQ P  P   PP        P    +            PP+  +  P +  A+PP  P+
Sbjct: 404 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 463

Query: 54  AASPCLGPVAAAGSGLRRGAEGILAPQPP--PPQQHQERPGAAAIG--SARGQSTGKGPP 109
           A  P   P + A   L+      + P PP  PP      P   A    +A      K PP
Sbjct: 464 ATPPSQAPPSLAAPPLQ------VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 517

Query: 110 QSP 112
           Q+P
Sbjct: 518 QAP 520



 Score = 37.0 bits (84), Expect = 0.099
 Identities = 39/122 (31%), Positives = 48/122 (39%), Gaps = 30/122 (24%)

Query: 13  PQQPP--PTQQAVARRPPGGTSPPNGGLPGP---LATSAAPPGPP--AAASPCLGPVAAA 65
           P  PP  PT QA  RRPP  T  P+  + GP   LA +  PP PP  + +S   GP  A 
Sbjct: 574 PPSPPASPTLQA-PRRPP--TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 630

Query: 66  GS-----------GLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPVF 114
            S           G   G EG  A  PPP          A + +    +  +GP     F
Sbjct: 631 HSSSATSTPEELRGYDSGPEGGAAASPPPD---------AELAACHPAAWSRGPAPPLAF 681

Query: 115 EG 116
            G
Sbjct: 682 RG 683



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 35/124 (28%), Positives = 47/124 (37%), Gaps = 20/124 (16%)

Query: 3   KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAA-------- 54
           KP+ LQ    PQ  PP + A     P  +SP     P     S APP  PA         
Sbjct: 273 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTC 332

Query: 55  --ASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK---GPP 109
             A+P   P+A          + + +P   PP Q        ++GS   Q+T      PP
Sbjct: 333 QLATPL--PLAPPSPSAPPSLQTLPSPPATPPSQ-----ATTSLGSPTLQATHSFLPSPP 385

Query: 110 QSPV 113
            SP+
Sbjct: 386 LSPL 389



 Score = 33.9 bits (76), Expect = 0.84
 Identities = 36/125 (28%), Positives = 43/125 (34%), Gaps = 27/125 (21%)

Query: 4   PQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLAT---------SAAPPGPPAA 54
           P PL  P      PP Q      PP   +PP   LP P A+         SA+ P  P A
Sbjct: 502 PPPLAAPPLQLAKPPPQA-----PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 556

Query: 55  ASPCLGPVAAAGSGLRRGAEGILAPQPP--PPQQHQER-----PGAAAIGSARGQSTGKG 107
             P   P   A   L+      + P PP  P  Q   R     P  +  G     +   G
Sbjct: 557 TPPPQAPPVLAAPLLQ------VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 610

Query: 108 PPQSP 112
           PP  P
Sbjct: 611 PPPPP 615



 Score = 32.0 bits (71), Expect = 3.2
 Identities = 30/100 (30%), Positives = 36/100 (36%), Gaps = 12/100 (12%)

Query: 10  PSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGL 69
           P  P   PP Q      PP    PP   L  P +  A+PP  P A      P A A   L
Sbjct: 385 PLSPLATPPPQ-----APPALALPP---LQAPPSPPASPPLSPLATPSPQAPNALAVHLL 436

Query: 70  RRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109
               +   +P P PP Q    P A+   S       + PP
Sbjct: 437 ----QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 472



 Score = 31.6 bits (70), Expect = 4.2
 Identities = 33/119 (27%), Positives = 43/119 (36%), Gaps = 21/119 (17%)

Query: 6   PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPG-P---PAAASPCLGP 61
           P+Q P  P   PP   +     P   +PP+   P PL    +PP  P   P+A  P   P
Sbjct: 447 PVQAPFSPPASPPVSPSAT---PPSQAPPSLAAP-PLQVPPSPPASPPMSPSATPPPQAP 502

Query: 62  VAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGP-------PQSPV 113
              A   L+      LA  PP        P   A+ S      G+ P       P SP+
Sbjct: 503 PPLAAPPLQ------LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 555



 Score = 31.6 bits (70), Expect = 4.2
 Identities = 29/91 (31%), Positives = 34/91 (37%), Gaps = 13/91 (14%)

Query: 16  PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEG 75
           PPP  +  A  P   +  P      PLA   AP G P    P  GP +A G       EG
Sbjct: 657 PPPDAELAACHPAAWSRGP----APPLAFRGAP-GAPLPWPPATGPGSADGLCTIYETEG 711

Query: 76  ILAPQPPPPQQHQERPGAAAIGSARGQSTGK 106
                   P+     PGA   G + G S GK
Sbjct: 712 --------PESATPAPGALDPGPSPGTSGGK 734


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 146/545 (26%), Positives = 196/545 (35%), Gaps = 93/545 (17%)

Query: 561  ENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTES-VSDKEDKPPLAPSGGTE 619
            E  +DP PP + K      ++E DGL     M +  S  + S +     K P +P G T 
Sbjct: 546  EKPVDP-PPFMFKPV----KEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTS 600

Query: 620  GPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKST 679
               +      S   SP        D      AE VKKS      +  +P K      +  
Sbjct: 601  PINEDIRS--SGRNSPSAASTSSNDSK----AETVKKSAKKVKEEASSPLKSNKRQREKV 654

Query: 680  STPTSPGPRTHST---------PSIPVLTAGQS---------GLYSPQYISYIPQIHMGP 721
            ++ T    RT S          P+ P    G+S         G   P+ I    +    P
Sbjct: 655  ASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNR-STSP 713

Query: 722  AVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAA 781
            ++ +PQ       +S   QQ   +    +L         P+SAPP        GP     
Sbjct: 714  SIPSPQDNESDSDSSA--QQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP----- 766

Query: 782  TPYSSYIPYNPQQFP-GQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
            TP ++ +P  PQ  P    A  QP A  P+ PV    +Q  P +     HPQ   S   P
Sbjct: 767  TPSATAVP--PQGSPTASQAPNQPQA--PTAPVPHTHIQQAPAL-----HPQRPPSPHPP 817

Query: 841  QYPSAEQPTPQALYATVHQSYPHHATQ-LHAHQPQPATTPTGSQPQSQHAAPS-----PV 894
             +PS   P      +    S P HA   LH   P P      + P  QH  P      P 
Sbjct: 818  PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGP-PGPHSLQAGPLLQHPGPPQPFGLPP 876

Query: 895  QHQAGQAPHLGSGQ----PQQNLYHPGALTGT----PPS---LPPGPSAQ--------SP 935
            Q   GQAP LG+      P  +L  P + +      PP    LPP P A         +P
Sbjct: 877  QASQGQAP-LGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP 935

Query: 936  QSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQ 995
                P P A     H   P  F+  A++        +++    HP + HPP + L+  PQ
Sbjct: 936  IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM--PQ 993

Query: 996  SHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQ------GEQP--GQAPGFPGGADDRIP 1047
            S   P   A P    P L+ S   P P   HP         QP   Q P  PGG     P
Sbjct: 994  SQPLPSSPAQP----PGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGP----P 1045

Query: 1048 PLPPP 1052
            P+ PP
Sbjct: 1046 PITPP 1050



 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 133/610 (21%), Positives = 211/610 (34%), Gaps = 109/610 (17%)

Query: 430  SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVS--DP 487
            SG+ S+    + G M   RS +   PA  S      PI   + +S  + P  +S S  D 
Sbjct: 567  SGKHSMRTRRSRGSMSTLRSGRKKQPA--SPDGRTSPINEDIRSSGRNSPSAASTSSNDS 624

Query: 488  GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547
               ++  ++ K+    +   + + ++  +     E A         +   K+ + +E+ +
Sbjct: 625  KAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEAD--------RTSSKKTKTQEISR 676

Query: 548  FGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD--GLLTSEPMGSPVSSKTESVSD 605
                    P+S  E   +    R + +E     K++D     TS  + SP  ++++S S 
Sbjct: 677  --------PNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSS 728

Query: 606  KEDK-----PPL--APSGGTEGPEQPPP---------PCPSQTGSPPVGLIKGEDKDEGP 649
             + +     PP   AP+G T  P   PP         P PS T  PP G          P
Sbjct: 729  AQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQP 788

Query: 650  VAEQV--------KKSTLNPNAKEF-------NPTKPLLSVNKSTSTPTSPGPRTHSTPS 694
             A           +   L+P            +P  PL  +  S   P++P   +H+ P 
Sbjct: 789  QAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP---SHAQP- 844

Query: 695  IPVLTAGQSGLYS------------PQYISYIPQIHMGPA---VQAPQMYPYPVSNSVPG 739
             P+   G  G +S            PQ     PQ   G A         YP+  S  +P 
Sbjct: 845  -PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH-TSLQLPA 902

Query: 740  QQGKYRGAKG-------------------------SLPPQRSDQHQPASAPPMMQAAAAA 774
             Q   +  +                           LP  ++ +H P  + P   +  A 
Sbjct: 903  SQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNAN 962

Query: 775  GPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAH-YPSQPVFAPML-QSNPRMLTSGSHPQ 832
             PP  A  P SS   ++P      P  + P +   PS P   P L QS        SHP 
Sbjct: 963  LPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPP 1022

Query: 833  AIVSSSTPQYPSAEQP-TPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAP 891
              +    PQ P A+ P  P         + P  +T        PA   T +QP    AA 
Sbjct: 1023 TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP-------PAGPGTSAQPPCSGAAA 1075

Query: 892  SPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQ 951
            S      G +  L + Q ++          +PP  P  PS +      P  A+  A  ++
Sbjct: 1076 SGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYK 1135

Query: 952  QLPHGFTNMA 961
             L  G+ + A
Sbjct: 1136 HLDRGYNSCA 1145



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 135/639 (21%), Positives = 209/639 (32%), Gaps = 114/639 (17%)

Query: 374  PGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSP--SNRPSG 431
            P L  L     HH  ++ P P          PS  SP     L  ++ L  P  S+ P+G
Sbjct: 967  PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPS--SPAQPPGLTQSQNLPPPPASHPPTG 1024

Query: 432  ETSVPP-PPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPG-- 488
               V P PP     + P  P    P P   S   PP G   P +SA  P + + +  G  
Sbjct: 1025 LHQVAPQPPFAQHPFVPGGPPPITP-PTCPSTSTPPAG---PGTSAQPPCSGAAASGGSI 1080

Query: 489  VGSISPASPKISLAPTDVKELSTKE----PGRTLEPQ-----------ELARIAGKVPGL 533
             G  S   P + +    + +    E    P R+  P+           + AR    +   
Sbjct: 1081 AGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRG 1140

Query: 534  QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593
             N   R  L  +   G++   +   + E +      +  +E  + KEKE +     E   
Sbjct: 1141 YNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERERER 1200

Query: 594  SPVSSKTESVSDKEDK--PPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVA 651
                +   S S  E +   P     G   P   PPP       P +G             
Sbjct: 1201 EAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIG------------- 1247

Query: 652  EQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP--TSPGPRTHS-----TPSIPVLTAGQSG 704
                            P  P L      + P   SP  R H       P+ P+L     G
Sbjct: 1248 ----------------PDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPG 1291

Query: 705  LYSPQYISYIPQIHMGPAVQAPQMYPYPV-SNSVPGQQGKYRGAKG-SLPPQRSDQHQPA 762
            LY+           + P ++  ++    +    +  ++ + R   G  + P   D   PA
Sbjct: 1292 LYN-----------VDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPA 1340

Query: 763  SAPP--MMQAAAAAGPPLVAATPYSSYIP-YNP---QQFPGQPAMMQPMAHYPSQPVFAP 816
            + P     + +A   PP     P++S+ P  NP   ++       ++P   YP +     
Sbjct: 1341 ANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAER 1400

Query: 817  MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQP- 875
            +       LTS    +  + + TP                 H  + H  + LH HQ  P 
Sbjct: 1401 IHAERMASLTSDPLARLQMFNVTPH----------------HHQHSHIHSHLHLHQQDPL 1444

Query: 876  ---ATTPTGSQPQSQHAAP--SPVQHQAGQAPHLGSGQP---QQNLYHPGALTGTPPSL- 926
               +  P         A P  +   +  G  P+   GQP    + L HP   T  P  L 
Sbjct: 1445 HQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLP 1504

Query: 927  ----PPGPSAQSPQSSFPQPAAVYAI-HHQQLPHGFTNM 960
                PP  +A   Q+   Q A +  +   QQ  HG  +M
Sbjct: 1505 GAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHGHPHM 1543



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 39/134 (29%), Positives = 51/134 (38%), Gaps = 32/134 (23%)

Query: 2    LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNG-----------------GLPGPL-- 42
            L PQ    PS P QPP   Q+    PP  + PP G                 G P P+  
Sbjct: 990  LMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITP 1049

Query: 43   ----ATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGS 98
                +TS  P GP  +A P     AA+G  +  G+       P P  Q +E     A+  
Sbjct: 1050 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSS-----CPLPTVQIKEE----ALDD 1100

Query: 99   ARGQSTGKGPPQSP 112
            A    +   PP+SP
Sbjct: 1101 AEEPESPPPPPRSP 1114



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 92/374 (24%), Positives = 125/374 (33%), Gaps = 82/374 (21%)

Query: 371  GGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS 430
            G  P  SS PP  P      +PGP   A  +             P +G+ T S   N+P 
Sbjct: 746  GVTPAPSSAPPGTPQL---PTPGPTPSATAV-------------PPQGSPTASQAPNQPQ 789

Query: 431  GETSVPPPPAVGR---MYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDP 487
              T+  P   + +   ++P R P   +P P     P PP+     T SA  P   S + P
Sbjct: 790  APTAPVPHTHIQQAPALHPQRPP---SPHPPPHPSPHPPLQPL--TGSAGQPSAPSHAQP 844

Query: 488  GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547
             +    P  P    A   ++     +P   L PQ      G+ P   +    +    L+ 
Sbjct: 845  PLHGQGPPGPHSLQAGPLLQHPGPPQP-FGLPPQ---ASQGQAPLGTSPAAAYPHTSLQL 900

Query: 548  FGAQFKLQPSSSP-ENSLDPFP-------------------PRILKEEPK---GKEKEVD 584
              +Q  LQ    P E  L P P                   P+  K  P         ++
Sbjct: 901  PASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 960

Query: 585  GLLTSEPMGSPVSSKTESVSDKEDKPPL--------------APSGGTEGPEQPPPPCPS 630
              L   P   P+SS +         PPL               P G T+    PPPP   
Sbjct: 961  ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP--- 1017

Query: 631  QTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTH 690
                PP GL   +   + P A+        P      PT P      STSTP + GP T 
Sbjct: 1018 -ASHPPTGL--HQVAPQPPFAQHPFVPGGPPPITP--PTCP------STSTPPA-GPGTS 1065

Query: 691  STPSIPVLTAGQSG 704
            + P  P   A  SG
Sbjct: 1066 AQP--PCSGAAASG 1077



 Score = 38.9 bits (89), Expect = 0.026
 Identities = 38/118 (32%), Positives = 46/118 (38%), Gaps = 10/118 (8%)

Query: 4   PQPLQQPSQPQQP----PPT--QQAVA---RRPPGGTSPPNGGLPGPLATSAAPPGPPAA 54
           P   Q P+QPQ P    P T  QQA A   +RPP    PP+     PL       G P+A
Sbjct: 779 PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSA 838

Query: 55  ASPCLGPVAAAG-SGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111
            S    P+   G  G      G L   P PPQ     P A+   +  G S     P +
Sbjct: 839 PSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHT 896



 Score = 37.0 bits (84), Expect = 0.099
 Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 6/110 (5%)

Query: 6   PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAA 65
           P  Q ++       QQ + +  P     P G  P P   S+APPG P   +P   P A A
Sbjct: 716 PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP---SSAPPGTPQLPTPGPTPSATA 772

Query: 66  --GSGLRRGAEGILAPQ-PPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
               G    ++    PQ P  P  H     A A+   R  S    P  SP
Sbjct: 773 VPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP 822



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 30/111 (27%), Positives = 38/111 (34%), Gaps = 7/111 (6%)

Query: 9   QPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSG 68
           QP   Q P     A +  PPG    P  G P P AT+  P G P A+     P A     
Sbjct: 737 QPPALQAPTGVTPAPSSAPPGTPQLPTPG-PTPSATAVPPQGSPTASQAPNQPQAPTAPV 795

Query: 69  LRRGAEGILA------PQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPV 113
                +   A      P P PP      P    +  + GQ +     Q P+
Sbjct: 796 PHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL 846



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 33/111 (29%), Positives = 42/111 (37%), Gaps = 15/111 (13%)

Query: 2    LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
            L P PL  P   + PP T       P     PP+   P P + +A  P PPA     L P
Sbjct: 918  LPPAPLAMP-HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPA-----LKP 971

Query: 62   VAAAGSGLRRGAEGILAPQPPPPQ---QHQERPGAAAIGSARGQSTGKGPP 109
            +++  +     A       PPP Q   Q Q  P + A      QS    PP
Sbjct: 972  LSSLSTHHPPSA------HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 1016


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 146/545 (26%), Positives = 196/545 (35%), Gaps = 93/545 (17%)

Query: 561  ENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTES-VSDKEDKPPLAPSGGTE 619
            E  +DP PP + K      ++E DGL     M +  S  + S +     K P +P G T 
Sbjct: 546  EKPVDP-PPFMFKPV----KEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTS 600

Query: 620  GPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKST 679
               +      S   SP        D      AE VKKS      +  +P K      +  
Sbjct: 601  PINEDIRS--SGRNSPSAASTSSNDSK----AETVKKSAKKVKEEASSPLKSNKRQREKV 654

Query: 680  STPTSPGPRTHST---------PSIPVLTAGQS---------GLYSPQYISYIPQIHMGP 721
            ++ T    RT S          P+ P    G+S         G   P+ I    +    P
Sbjct: 655  ASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNR-STSP 713

Query: 722  AVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAA 781
            ++ +PQ       +S   QQ   +    +L         P+SAPP        GP     
Sbjct: 714  SIPSPQDNESDSDSSA--QQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP----- 766

Query: 782  TPYSSYIPYNPQQFP-GQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTP 840
            TP ++ +P  PQ  P    A  QP A  P+ PV    +Q  P +     HPQ   S   P
Sbjct: 767  TPSATAVP--PQGSPTASQAPNQPQA--PTAPVPHTHIQQAPAL-----HPQRPPSPHPP 817

Query: 841  QYPSAEQPTPQALYATVHQSYPHHATQ-LHAHQPQPATTPTGSQPQSQHAAPS-----PV 894
             +PS   P      +    S P HA   LH   P P      + P  QH  P      P 
Sbjct: 818  PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGP-PGPHSLQAGPLLQHPGPPQPFGLPP 876

Query: 895  QHQAGQAPHLGSGQ----PQQNLYHPGALTGT----PPS---LPPGPSAQ--------SP 935
            Q   GQAP LG+      P  +L  P + +      PP    LPP P A         +P
Sbjct: 877  QASQGQAP-LGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP 935

Query: 936  QSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQ 995
                P P A     H   P  F+  A++        +++    HP + HPP + L+  PQ
Sbjct: 936  IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM--PQ 993

Query: 996  SHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQ------GEQP--GQAPGFPGGADDRIP 1047
            S   P   A P    P L+ S   P P   HP         QP   Q P  PGG     P
Sbjct: 994  SQPLPSSPAQP----PGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGP----P 1045

Query: 1048 PLPPP 1052
            P+ PP
Sbjct: 1046 PITPP 1050



 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 133/610 (21%), Positives = 211/610 (34%), Gaps = 109/610 (17%)

Query: 430  SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVS--DP 487
            SG+ S+    + G M   RS +   PA  S      PI   + +S  + P  +S S  D 
Sbjct: 567  SGKHSMRTRRSRGSMSTLRSGRKKQPA--SPDGRTSPINEDIRSSGRNSPSAASTSSNDS 624

Query: 488  GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547
               ++  ++ K+    +   + + ++  +     E A         +   K+ + +E+ +
Sbjct: 625  KAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEAD--------RTSSKKTKTQEISR 676

Query: 548  FGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD--GLLTSEPMGSPVSSKTESVSD 605
                    P+S  E   +    R + +E     K++D     TS  + SP  ++++S S 
Sbjct: 677  --------PNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSS 728

Query: 606  KEDK-----PPL--APSGGTEGPEQPPP---------PCPSQTGSPPVGLIKGEDKDEGP 649
             + +     PP   AP+G T  P   PP         P PS T  PP G          P
Sbjct: 729  AQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQP 788

Query: 650  VAEQV--------KKSTLNPNAKEF-------NPTKPLLSVNKSTSTPTSPGPRTHSTPS 694
             A           +   L+P            +P  PL  +  S   P++P   +H+ P 
Sbjct: 789  QAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP---SHAQP- 844

Query: 695  IPVLTAGQSGLYS------------PQYISYIPQIHMGPA---VQAPQMYPYPVSNSVPG 739
             P+   G  G +S            PQ     PQ   G A         YP+  S  +P 
Sbjct: 845  -PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH-TSLQLPA 902

Query: 740  QQGKYRGAKG-------------------------SLPPQRSDQHQPASAPPMMQAAAAA 774
             Q   +  +                           LP  ++ +H P  + P   +  A 
Sbjct: 903  SQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNAN 962

Query: 775  GPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAH-YPSQPVFAPML-QSNPRMLTSGSHPQ 832
             PP  A  P SS   ++P      P  + P +   PS P   P L QS        SHP 
Sbjct: 963  LPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPP 1022

Query: 833  AIVSSSTPQYPSAEQP-TPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAP 891
              +    PQ P A+ P  P         + P  +T        PA   T +QP    AA 
Sbjct: 1023 TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP-------PAGPGTSAQPPCSGAAA 1075

Query: 892  SPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQ 951
            S      G +  L + Q ++          +PP  P  PS +      P  A+  A  ++
Sbjct: 1076 SGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYK 1135

Query: 952  QLPHGFTNMA 961
             L  G+ + A
Sbjct: 1136 HLDRGYNSCA 1145



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 135/639 (21%), Positives = 209/639 (32%), Gaps = 114/639 (17%)

Query: 374  PGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSP--SNRPSG 431
            P L  L     HH  ++ P P          PS  SP     L  ++ L  P  S+ P+G
Sbjct: 967  PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPS--SPAQPPGLTQSQNLPPPPASHPPTG 1024

Query: 432  ETSVPP-PPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPG-- 488
               V P PP     + P  P    P P   S   PP G   P +SA  P + + +  G  
Sbjct: 1025 LHQVAPQPPFAQHPFVPGGPPPITP-PTCPSTSTPPAG---PGTSAQPPCSGAAASGGSI 1080

Query: 489  VGSISPASPKISLAPTDVKELSTKE----PGRTLEPQ-----------ELARIAGKVPGL 533
             G  S   P + +    + +    E    P R+  P+           + AR    +   
Sbjct: 1081 AGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRG 1140

Query: 534  QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593
             N   R  L  +   G++   +   + E +      +  +E  + KEKE +     E   
Sbjct: 1141 YNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERERER 1200

Query: 594  SPVSSKTESVSDKEDK--PPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVA 651
                +   S S  E +   P     G   P   PPP       P +G             
Sbjct: 1201 EAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIG------------- 1247

Query: 652  EQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP--TSPGPRTHS-----TPSIPVLTAGQSG 704
                            P  P L      + P   SP  R H       P+ P+L     G
Sbjct: 1248 ----------------PDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPG 1291

Query: 705  LYSPQYISYIPQIHMGPAVQAPQMYPYPV-SNSVPGQQGKYRGAKG-SLPPQRSDQHQPA 762
            LY+           + P ++  ++    +    +  ++ + R   G  + P   D   PA
Sbjct: 1292 LYN-----------VDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPA 1340

Query: 763  SAPP--MMQAAAAAGPPLVAATPYSSYIP-YNP---QQFPGQPAMMQPMAHYPSQPVFAP 816
            + P     + +A   PP     P++S+ P  NP   ++       ++P   YP +     
Sbjct: 1341 ANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAER 1400

Query: 817  MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQP- 875
            +       LTS    +  + + TP                 H  + H  + LH HQ  P 
Sbjct: 1401 IHAERMASLTSDPLARLQMFNVTPH----------------HHQHSHIHSHLHLHQQDPL 1444

Query: 876  ---ATTPTGSQPQSQHAAP--SPVQHQAGQAPHLGSGQP---QQNLYHPGALTGTPPSL- 926
               +  P         A P  +   +  G  P+   GQP    + L HP   T  P  L 
Sbjct: 1445 HQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLP 1504

Query: 927  ----PPGPSAQSPQSSFPQPAAVYAI-HHQQLPHGFTNM 960
                PP  +A   Q+   Q A +  +   QQ  HG  +M
Sbjct: 1505 GAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHGHPHM 1543



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 39/134 (29%), Positives = 51/134 (38%), Gaps = 32/134 (23%)

Query: 2    LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNG-----------------GLPGPL-- 42
            L PQ    PS P QPP   Q+    PP  + PP G                 G P P+  
Sbjct: 990  LMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITP 1049

Query: 43   ----ATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGS 98
                +TS  P GP  +A P     AA+G  +  G+       P P  Q +E     A+  
Sbjct: 1050 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSS-----CPLPTVQIKEE----ALDD 1100

Query: 99   ARGQSTGKGPPQSP 112
            A    +   PP+SP
Sbjct: 1101 AEEPESPPPPPRSP 1114



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 92/374 (24%), Positives = 125/374 (33%), Gaps = 82/374 (21%)

Query: 371  GGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS 430
            G  P  SS PP  P      +PGP   A  +             P +G+ T S   N+P 
Sbjct: 746  GVTPAPSSAPPGTPQL---PTPGPTPSATAV-------------PPQGSPTASQAPNQPQ 789

Query: 431  GETSVPPPPAVGR---MYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDP 487
              T+  P   + +   ++P R P   +P P     P PP+     T SA  P   S + P
Sbjct: 790  APTAPVPHTHIQQAPALHPQRPP---SPHPPPHPSPHPPLQPL--TGSAGQPSAPSHAQP 844

Query: 488  GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547
             +    P  P    A   ++     +P   L PQ      G+ P   +    +    L+ 
Sbjct: 845  PLHGQGPPGPHSLQAGPLLQHPGPPQP-FGLPPQ---ASQGQAPLGTSPAAAYPHTSLQL 900

Query: 548  FGAQFKLQPSSSP-ENSLDPFP-------------------PRILKEEPK---GKEKEVD 584
              +Q  LQ    P E  L P P                   P+  K  P         ++
Sbjct: 901  PASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 960

Query: 585  GLLTSEPMGSPVSSKTESVSDKEDKPPL--------------APSGGTEGPEQPPPPCPS 630
              L   P   P+SS +         PPL               P G T+    PPPP   
Sbjct: 961  ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP--- 1017

Query: 631  QTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTH 690
                PP GL   +   + P A+        P      PT P      STSTP + GP T 
Sbjct: 1018 -ASHPPTGL--HQVAPQPPFAQHPFVPGGPPPITP--PTCP------STSTPPA-GPGTS 1065

Query: 691  STPSIPVLTAGQSG 704
            + P  P   A  SG
Sbjct: 1066 AQP--PCSGAAASG 1077



 Score = 38.9 bits (89), Expect = 0.026
 Identities = 38/118 (32%), Positives = 46/118 (38%), Gaps = 10/118 (8%)

Query: 4   PQPLQQPSQPQQP----PPT--QQAVA---RRPPGGTSPPNGGLPGPLATSAAPPGPPAA 54
           P   Q P+QPQ P    P T  QQA A   +RPP    PP+     PL       G P+A
Sbjct: 779 PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSA 838

Query: 55  ASPCLGPVAAAG-SGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111
            S    P+   G  G      G L   P PPQ     P A+   +  G S     P +
Sbjct: 839 PSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHT 896



 Score = 37.0 bits (84), Expect = 0.099
 Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 6/110 (5%)

Query: 6   PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAA 65
           P  Q ++       QQ + +  P     P G  P P   S+APPG P   +P   P A A
Sbjct: 716 PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP---SSAPPGTPQLPTPGPTPSATA 772

Query: 66  --GSGLRRGAEGILAPQ-PPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
               G    ++    PQ P  P  H     A A+   R  S    P  SP
Sbjct: 773 VPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP 822



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 30/111 (27%), Positives = 38/111 (34%), Gaps = 7/111 (6%)

Query: 9   QPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSG 68
           QP   Q P     A +  PPG    P  G P P AT+  P G P A+     P A     
Sbjct: 737 QPPALQAPTGVTPAPSSAPPGTPQLPTPG-PTPSATAVPPQGSPTASQAPNQPQAPTAPV 795

Query: 69  LRRGAEGILA------PQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPV 113
                +   A      P P PP      P    +  + GQ +     Q P+
Sbjct: 796 PHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL 846



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 33/111 (29%), Positives = 42/111 (37%), Gaps = 15/111 (13%)

Query: 2    LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
            L P PL  P   + PP T       P     PP+   P P + +A  P PPA     L P
Sbjct: 918  LPPAPLAMP-HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPA-----LKP 971

Query: 62   VAAAGSGLRRGAEGILAPQPPPPQ---QHQERPGAAAIGSARGQSTGKGPP 109
            +++  +     A       PPP Q   Q Q  P + A      QS    PP
Sbjct: 972  LSSLSTHHPPSA------HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 1016


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 85.1 bits (209), Expect = 3e-16
 Identities = 141/529 (26%), Positives = 189/529 (35%), Gaps = 88/529 (16%)

Query: 577  KGKEKEVDGLLTSEPMGSPVSSKTES-VSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSP 635
            K  ++E DGL     M +  S  + S +     K P +P G T    +      S   SP
Sbjct: 3    KPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRS--SGRNSP 60

Query: 636  PVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHST--- 692
                    D      AE VKKS      +  +P K      +  ++ T    RT S    
Sbjct: 61   SAASTSSNDSK----AETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTK 116

Query: 693  ------PSIPVLTAGQS---------GLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSV 737
                  P+ P    G+S         G   P+ I    +    P++ +PQ       +S 
Sbjct: 117  TQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNR-STSPSIPSPQDNESDSDSSA 175

Query: 738  PGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFP- 796
              QQ   +    +L         P+SAPP        GP     TP ++ +P  PQ  P 
Sbjct: 176  --QQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGP-----TPSATAVP--PQGSPT 226

Query: 797  GQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYAT 856
               A  QP A  P+ PV    +Q  P +     HPQ   S   P +PS   P      + 
Sbjct: 227  ASQAPNQPQA--PTAPVPHTHIQQAPAL-----HPQRPPSPHPPPHPSPHPPLQPLTGSA 279

Query: 857  VHQSYPHHATQ-LHAHQPQPATTPTGSQPQSQHAAPS-----PVQHQAGQAPHLGSGQ-- 908
               S P HA   LH   P P      + P  QH  P      P Q   GQAP LG+    
Sbjct: 280  GQPSAPSHAQPPLHGQGP-PGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAP-LGTSPAA 337

Query: 909  --PQQNLYHPGALTGT----PPS---LPPGPSAQ--------SPQSSFPQPAAVYAIHHQ 951
              P  +L  P + +      PP    LPP P A         +P    P P A     H 
Sbjct: 338  AYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHL 397

Query: 952  QLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVP 1011
              P  F+  A++        +++    HP + HPP + L+  PQS   P   A P    P
Sbjct: 398  SGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM--PQSQPLPSSPAQP----P 451

Query: 1012 ALSASTPSPYPYIGHPQ------GEQP--GQAPGFPGGADDRIPPLPPP 1052
             L+ S   P P   HP         QP   Q P  PGG     PP+ PP
Sbjct: 452  GLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGP----PPITPP 496



 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 133/610 (21%), Positives = 211/610 (34%), Gaps = 109/610 (17%)

Query: 430 SGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVS--DP 487
           SG+ S+    + G M   RS +   PA  S      PI   + +S  + P  +S S  D 
Sbjct: 13  SGKHSMRTRRSRGSMSTLRSGRKKQPA--SPDGRTSPINEDIRSSGRNSPSAASTSSNDS 70

Query: 488 GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547
              ++  ++ K+    +   + + ++  +     E A         +   K+ + +E+ +
Sbjct: 71  KAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEAD--------RTSSKKTKTQEISR 122

Query: 548 FGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD--GLLTSEPMGSPVSSKTESVSD 605
                   P+S  E   +    R + +E     K++D     TS  + SP  ++++S S 
Sbjct: 123 --------PNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSS 174

Query: 606 KEDK-----PPL--APSGGTEGPEQPPP---------PCPSQTGSPPVGLIKGEDKDEGP 649
            + +     PP   AP+G T  P   PP         P PS T  PP G          P
Sbjct: 175 AQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQP 234

Query: 650 VAEQV--------KKSTLNPNAKEF-------NPTKPLLSVNKSTSTPTSPGPRTHSTPS 694
            A           +   L+P            +P  PL  +  S   P++P   +H+ P 
Sbjct: 235 QAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAP---SHAQP- 290

Query: 695 IPVLTAGQSGLYS------------PQYISYIPQIHMGPA---VQAPQMYPYPVSNSVPG 739
            P+   G  G +S            PQ     PQ   G A         YP+  S  +P 
Sbjct: 291 -PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH-TSLQLPA 348

Query: 740 QQGKYRGAKG-------------------------SLPPQRSDQHQPASAPPMMQAAAAA 774
            Q   +  +                           LP  ++ +H P  + P   +  A 
Sbjct: 349 SQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNAN 408

Query: 775 GPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAH-YPSQPVFAPML-QSNPRMLTSGSHPQ 832
            PP  A  P SS   ++P      P  + P +   PS P   P L QS        SHP 
Sbjct: 409 LPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPP 468

Query: 833 AIVSSSTPQYPSAEQP-TPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAP 891
             +    PQ P A+ P  P         + P  +T        PA   T +QP    AA 
Sbjct: 469 TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP-------PAGPGTSAQPPCSGAAA 521

Query: 892 SPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQ 951
           S      G +  L + Q ++          +PP  P  PS +      P  A+  A  ++
Sbjct: 522 SGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYK 581

Query: 952 QLPHGFTNMA 961
            L  G+ + A
Sbjct: 582 HLDRGYNSCA 591



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 135/639 (21%), Positives = 209/639 (32%), Gaps = 114/639 (17%)

Query: 374 PGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSP--SNRPSG 431
           P L  L     HH  ++ P P          PS  SP     L  ++ L  P  S+ P+G
Sbjct: 413 PALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPS--SPAQPPGLTQSQNLPPPPASHPPTG 470

Query: 432 ETSVPP-PPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPG-- 488
              V P PP     + P  P    P P   S   PP G   P +SA  P + + +  G  
Sbjct: 471 LHQVAPQPPFAQHPFVPGGPPPITP-PTCPSTSTPPAG---PGTSAQPPCSGAAASGGSI 526

Query: 489 VGSISPASPKISLAPTDVKELSTKE----PGRTLEPQ-----------ELARIAGKVPGL 533
            G  S   P + +    + +    E    P R+  P+           + AR    +   
Sbjct: 527 AGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRG 586

Query: 534 QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593
            N   R  L  +   G++   +   + E +      +  +E  + KEKE +     E   
Sbjct: 587 YNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKERERERERER 646

Query: 594 SPVSSKTESVSDKEDK--PPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVA 651
               +   S S  E +   P     G   P   PPP       P +G             
Sbjct: 647 EAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIG------------- 693

Query: 652 EQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP--TSPGPRTHS-----TPSIPVLTAGQSG 704
                           P  P L      + P   SP  R H       P+ P+L     G
Sbjct: 694 ----------------PDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPG 737

Query: 705 LYSPQYISYIPQIHMGPAVQAPQMYPYPV-SNSVPGQQGKYRGAKG-SLPPQRSDQHQPA 762
           LY+           + P ++  ++    +    +  ++ + R   G  + P   D   PA
Sbjct: 738 LYN-----------VDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPA 786

Query: 763 SAPP--MMQAAAAAGPPLVAATPYSSYIP-YNP---QQFPGQPAMMQPMAHYPSQPVFAP 816
           + P     + +A   PP     P++S+ P  NP   ++       ++P   YP +     
Sbjct: 787 ANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAER 846

Query: 817 MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQP- 875
           +       LTS    +  + + TP                 H  + H  + LH HQ  P 
Sbjct: 847 IHAERMASLTSDPLARLQMFNVTPH----------------HHQHSHIHSHLHLHQQDPL 890

Query: 876 ---ATTPTGSQPQSQHAAP--SPVQHQAGQAPHLGSGQP---QQNLYHPGALTGTPPSL- 926
              +  P         A P  +   +  G  P+   GQP    + L HP   T  P  L 
Sbjct: 891 HQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLP 950

Query: 927 ----PPGPSAQSPQSSFPQPAAVYAI-HHQQLPHGFTNM 960
               PP  +A   Q+   Q A +  +   QQ  HG  +M
Sbjct: 951 GAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHGHPHM 989



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 39/134 (29%), Positives = 51/134 (38%), Gaps = 32/134 (23%)

Query: 2   LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNG-----------------GLPGPL-- 42
           L PQ    PS P QPP   Q+    PP  + PP G                 G P P+  
Sbjct: 436 LMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITP 495

Query: 43  ----ATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGS 98
               +TS  P GP  +A P     AA+G  +  G+       P P  Q +E     A+  
Sbjct: 496 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSS-----CPLPTVQIKEE----ALDD 546

Query: 99  ARGQSTGKGPPQSP 112
           A    +   PP+SP
Sbjct: 547 AEEPESPPPPPRSP 560



 Score = 41.2 bits (95), Expect = 0.005
 Identities = 92/374 (24%), Positives = 125/374 (33%), Gaps = 82/374 (21%)

Query: 371 GGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS 430
           G  P  SS PP  P      +PGP   A  +             P +G+ T S   N+P 
Sbjct: 192 GVTPAPSSAPPGTPQL---PTPGPTPSATAV-------------PPQGSPTASQAPNQPQ 235

Query: 431 GETSVPPPPAVGR---MYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDP 487
             T+  P   + +   ++P R P   +P P     P PP+     T SA  P   S + P
Sbjct: 236 APTAPVPHTHIQQAPALHPQRPP---SPHPPPHPSPHPPLQPL--TGSAGQPSAPSHAQP 290

Query: 488 GVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRK 547
            +    P  P    A   ++     +P   L PQ      G+ P   +    +    L+ 
Sbjct: 291 PLHGQGPPGPHSLQAGPLLQHPGPPQP-FGLPPQ---ASQGQAPLGTSPAAAYPHTSLQL 346

Query: 548 FGAQFKLQPSSSP-ENSLDPFP-------------------PRILKEEPK---GKEKEVD 584
             +Q  LQ    P E  L P P                   P+  K  P         ++
Sbjct: 347 PASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMN 406

Query: 585 GLLTSEPMGSPVSSKTESVSDKEDKPPL--------------APSGGTEGPEQPPPPCPS 630
             L   P   P+SS +         PPL               P G T+    PPPP   
Sbjct: 407 ANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPP--- 463

Query: 631 QTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTH 690
               PP GL   +   + P A+        P      PT P      STSTP + GP T 
Sbjct: 464 -ASHPPTGL--HQVAPQPPFAQHPFVPGGPPPITP--PTCP------STSTPPA-GPGTS 511

Query: 691 STPSIPVLTAGQSG 704
           + P  P   A  SG
Sbjct: 512 AQP--PCSGAAASG 523



 Score = 38.9 bits (89), Expect = 0.026
 Identities = 38/118 (32%), Positives = 46/118 (38%), Gaps = 10/118 (8%)

Query: 4   PQPLQQPSQPQQP----PPT--QQAVA---RRPPGGTSPPNGGLPGPLATSAAPPGPPAA 54
           P   Q P+QPQ P    P T  QQA A   +RPP    PP+     PL       G P+A
Sbjct: 225 PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSA 284

Query: 55  ASPCLGPVAAAG-SGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111
            S    P+   G  G      G L   P PPQ     P A+   +  G S     P +
Sbjct: 285 PSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHT 342



 Score = 37.0 bits (84), Expect = 0.099
 Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 6/110 (5%)

Query: 6   PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAA 65
           P  Q ++       QQ + +  P     P G  P P   S+APPG P   +P   P A A
Sbjct: 162 PSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP---SSAPPGTPQLPTPGPTPSATA 218

Query: 66  --GSGLRRGAEGILAPQ-PPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
               G    ++    PQ P  P  H     A A+   R  S    P  SP
Sbjct: 219 VPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSP 268



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 30/111 (27%), Positives = 38/111 (34%), Gaps = 7/111 (6%)

Query: 9   QPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSG 68
           QP   Q P     A +  PPG    P  G P P AT+  P G P A+     P A     
Sbjct: 183 QPPALQAPTGVTPAPSSAPPGTPQLPTPG-PTPSATAVPPQGSPTASQAPNQPQAPTAPV 241

Query: 69  LRRGAEGILA------PQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSPV 113
                +   A      P P PP      P    +  + GQ +     Q P+
Sbjct: 242 PHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL 292



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 33/111 (29%), Positives = 42/111 (37%), Gaps = 15/111 (13%)

Query: 2   LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
           L P PL  P   + PP T       P     PP+   P P + +A  P PPA     L P
Sbjct: 364 LPPAPLAMP-HIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPA-----LKP 417

Query: 62  VAAAGSGLRRGAEGILAPQPPPPQ---QHQERPGAAAIGSARGQSTGKGPP 109
           +++  +     A       PPP Q   Q Q  P + A      QS    PP
Sbjct: 418 LSSLSTHHPPSA------HPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 462


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 80.9 bits (198), Expect = 6e-15
 Identities = 168/701 (23%), Positives = 242/701 (34%), Gaps = 168/701 (23%)

Query: 375  GLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETS 434
            GL++    G       SP   +   G+    S++S + +R +  A  +S     P G  S
Sbjct: 15   GLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQI--AAVMSRAQGLPKG--S 70

Query: 435  VPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISP 494
            VPP  A        SP       + +S P        P  S   P      DPG     P
Sbjct: 71   VPPAAA-------ESPSMHRKQELDSSHP--------PKQSGRPP------DPG----RP 105

Query: 495  ASPKISLA-PTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKF----G 549
            A P +S +  TD      K PGR+  P  ++        L+  + R  L+E  K     G
Sbjct: 106  AQPGLSKSRTTDTFRSEQKLPGRS--PSTIS--------LKESKSRTDLKEEHKSSMMPG 155

Query: 550  AQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKED- 608
               ++   S+  + ++ F P  L  + +  ++E              ++K + V  KE  
Sbjct: 156  FLSEVNALSAVSSVVNKFNPFDLISDSEASQEE--------------TTKKQKVVQKEQG 201

Query: 609  ------KPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPN 662
                  KPPL         +QPP P P Q G        G D    P+ +     +++  
Sbjct: 202  KPEGIIKPPLQ--------QQPPKPIPKQQG-------PGRD----PLQQDGTPKSISSQ 242

Query: 663  AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722
              E   ++P     K    PT      H+   +P+           Q  +  PQ      
Sbjct: 243  QPEKIKSQP-PGTGKPIQGPTQTPQTDHA--KLPL-----------QRDASRPQTKQADI 288

Query: 723  VQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAAT 782
            V+   + P   S S P  Q    G   +  P   ++ QP  A P  Q +    P  +A  
Sbjct: 289  VRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGH-EKSQPGPAKPPAQPSGLTKP--LAQQ 345

Query: 783  PYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQY 842
            P +   P  P   PG            ++P   P+  + P    +GS           + 
Sbjct: 346  PGTVKPPVQP---PG-----------TTKPPAQPLGPAKPPAQQTGS-----------EK 380

Query: 843  PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAG-QA 901
            PS+EQP P+AL      + P    +  A QP PA  PT      Q   P P+  Q G Q+
Sbjct: 381  PSSEQPGPKAL------AQPPGVGKTPAQQPGPAKPPT-----QQVGTPKPLAQQPGLQS 429

Query: 902  PHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMA 961
            P    G  +  +  PG   G  P+   GP   S Q + P           QLP       
Sbjct: 430  PAKAPGPTKTPVQQPG--PGKIPAQQAGPGKTSAQQTGPTKPP------SQLP------G 475

Query: 962  HVTQAHVQTGITAAPPPHPGAPHPP--QVMLLHPPQSHGGPPQGAVPQSGVPALSASTPS 1019
                   Q G    PP  PG+  PP  Q     PP    GP + +  Q G    S   PS
Sbjct: 476  PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPG----STKPPS 531

Query: 1020 PYPYIGHPQGEQPGQAPGFPGGADDRIP--------PLPPP 1052
              P    P  +QP  +P  P       P        PL PP
Sbjct: 532  QQPGSAKPSAQQP--SPAKPSAQQSTKPVSQTGSGKPLQPP 570



 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 157/690 (22%), Positives = 231/690 (33%), Gaps = 123/690 (17%)

Query: 333  QGSGRESPSLASREGKYIPLPQRVREGPR---GGVRCSSSRGG-------RPGLSSLPPR 382
            Q +G E PS      K +  P  V + P    G  +  + + G       +PGL S P +
Sbjct: 374  QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQS-PAK 432

Query: 383  --GPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGET--SVPPP 438
              GP       PGPG +      GP + S +   P +    L  P+  P  +   + PPP
Sbjct: 433  APGPTKTPVQQPGPG-KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPP 491

Query: 439  PAVGRMYPP-----------RSPKSAAPAPISASCPEPPI---GSAVPTSSASIPV---- 480
               G   PP           + P  A P+P      +PP    GSA P++    P     
Sbjct: 492  QQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSA 551

Query: 481  ---TSSVSDPGVG------SISPAS--------PK--ISLAPTDVKELSTKEPGRTLEPQ 521
               T  VS  G G      ++SP++        PK    L  T    L   E        
Sbjct: 552  QQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCT 611

Query: 522  ELARIAGKVPGLQNEQKRFQLEELRKFGAQFK------LQP-SSSPENSLDPFP----PR 570
            E       + G        +++E      Q K      L P  SSP+  L   P      
Sbjct: 612  ECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSA 671

Query: 571  ILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEG-----PEQPP 625
            + K  P+ ++       TS    +          + +  PPL       G      +QPP
Sbjct: 672  VSKSSPQPQQ-------TSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724

Query: 626  PPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSP 685
                    +PP       ++D+ PVA+   K       K   PT  L+S + +T+ P  P
Sbjct: 725  EADSLSKPAPPKEPSVPSEQDKAPVADDKPK-----QPKMVKPTTDLVSSSSATTKPDIP 779

Query: 686  GPRTHS------TPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPG 739
              +  S      TP +   +A  S  + P      P      A+  P      +S+  PG
Sbjct: 780  SSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSP--FDSKAIPRPASDSKIISH--PG 835

Query: 740  QQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQP 799
               + +G K   P Q+ +  +P  A   M     A P      P  S  P  P+   GQ 
Sbjct: 836  PSSESKGQKQVDPVQKKE--EPKKAQTKMSPKPDAKP-----MPKGSPTPPGPRPTAGQT 888

Query: 800  AMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQ 859
                  +  P +       QS    L  GS     ++ +    P+  Q T          
Sbjct: 889  VPTPQQSPKPQE-------QSRRFSLNLGS-----ITDAPKSQPTTPQETVTGKLFGFGA 936

Query: 860  SYPHHATQL--HAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPG 917
            S    A+ L   A QP P +      P  Q  AP+P Q    Q P   +GQ         
Sbjct: 937  SIFSQASNLISTAGQPGPHSQSGPGAPMKQ--APAPSQPPTSQGPPKSTGQ--------- 985

Query: 918  ALTGTPPSLPPGPSAQSPQSSFPQPAAVYA 947
            A      S+P     ++P +   +P A  A
Sbjct: 986  APPAPAKSIPVKKETKAPAAEKLEPKAEQA 1015



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 149/691 (21%), Positives = 211/691 (30%), Gaps = 135/691 (19%)

Query: 405  PSRMSPKAQRPLRG-----AKTLSSPSNRPSGETSVPP---PPAVGRMYPPRSPKSAAPA 456
            P +  PK Q P R          S  S +P    S PP    P  G    P++  +  P 
Sbjct: 215  PPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPL 274

Query: 457  PISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGR 516
               AS P+      V   S   P   S S P +   +P  P       +  +    +P  
Sbjct: 275  QRDASRPQTKQADIVRGESVK-PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP-- 331

Query: 517  TLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEP 576
              +P  L +   + PG    +   Q     K  AQ  L P+  P        P   +  P
Sbjct: 332  PAQPSGLTKPLAQQPG--TVKPPVQPPGTTKPPAQ-PLGPAKPPAQQTGSEKPSSEQPGP 388

Query: 577  KGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPP 636
            K   +      T      P    T+ V   +   PLA   G + P + P P  +    P 
Sbjct: 389  KALAQPPGVGKTPAQQPGPAKPPTQQVGTPK---PLAQQPGLQSPAKAPGPTKTPVQQPG 445

Query: 637  VGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIP 696
             G I  +    G             +A++  PTKP   +         PGP         
Sbjct: 446  PGKIPAQQAGPG-----------KTSAQQTGPTKPPSQL---------PGP--------- 476

Query: 697  VLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRS 756
                           +  P    GPA   PQ    P S   P QQ       GS  P   
Sbjct: 477  ---------------AKPPPQQPGPAKPPPQQ---PGSAKPPSQQ------PGSTKP--- 509

Query: 757  DQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAP 816
               QP  A P  Q   +  PP                    QP   +P A  PS    + 
Sbjct: 510  PPQQPGPAKPSPQQPGSTKPP------------------SQQPGSAKPSAQQPSPAKPSA 551

Query: 817  MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPA 876
               + P   T    P    + S    PSA+QP  Q L  T+      + T+L  H P+ A
Sbjct: 552  QQSTKPVSQTGSGKPLQPPTVS----PSAKQPPSQGLPKTICPLC--NTTELLLHVPEKA 605

Query: 877  TTPTGSQPQSQHAA-----PSPVQHQAGQ----------------APHLGSGQPQQNLYH 915
               T ++ Q+   +     P+P   +  +                AP   S QP+     
Sbjct: 606  NFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKT-A 664

Query: 916  PGALTGTPPSLPPGPSAQSPQ---------SSFPQPAAVYAIHHQQLPHGFTNMAHVTQA 966
            P   T       P P   SP+         S  P+P     +  Q   HG  +       
Sbjct: 665  PVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724

Query: 967  HVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGH 1026
               +    APP  P  P          P +   P Q  + +     +S+S+ +  P I  
Sbjct: 725  EADSLSKPAPPKEPSVPSEQD----KAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS 780

Query: 1027 PQGEQPGQAPGFPGGADDRIPP---LPPPGE 1054
             + +   +    P    D   P    PP GE
Sbjct: 781  SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGE 811



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 99/449 (22%), Positives = 159/449 (35%), Gaps = 78/449 (17%)

Query: 373  RPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGE 432
            +P L + P      +  SSP P   +   +  P +   KA  P +    +  P+   S  
Sbjct: 658  QPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPS 717

Query: 433  TSVPPPPAVGRMYPPRSPKSAA------PAPISASCPEPPIGSAVPTSSASIPVTSSVSD 486
                 PP    +  P  PK  +       AP++   P+ P    V  ++  +  +S+ + 
Sbjct: 718  AKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQP--KMVKPTTDLVSSSSATTK 775

Query: 487  PGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELR 546
            P + S    S         +K  S K P ++  P                      E++ 
Sbjct: 776  PDIPSSKVQSQAEEKTTPPLKTDSAK-PSQSFPPTG--------------------EKVS 814

Query: 547  KFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDK 606
             F ++   +P+S  +    P P      E KG +K+VD +   E    P  ++T+ +S K
Sbjct: 815  PFDSKAIPRPASDSKIISHPGP----SSESKG-QKQVDPVQKKE---EPKKAQTK-MSPK 865

Query: 607  EDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN----PN 662
             D  P+ P G       P PP P  T    V   +   K +    EQ ++ +LN     +
Sbjct: 866  PDAKPM-PKG------SPTPPGPRPTAGQTVPTPQQSPKPQ----EQSRRFSLNLGSITD 914

Query: 663  AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722
            A +  PT P  +V   T      G    S  S  + TAGQ G +S             P 
Sbjct: 915  APKSQPTTPQETV---TGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG-------APM 964

Query: 723  VQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPAS---------APPMMQAAAA 773
             QAP     P S   P   G+   A     P + +   PA+         AP + +    
Sbjct: 965  KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETE 1024

Query: 774  AGPPLV------AATPYSSYIPYNPQQFP 796
              PP +       A P  + +P   ++ P
Sbjct: 1025 KKPPPIKDSKSLTAEPQKAVLPTKLEKSP 1053



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 42/119 (35%), Positives = 53/119 (44%), Gaps = 17/119 (14%)

Query: 6   PLQQPSQPQQPPPTQQAVARRP----PGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
           P QQP   +  PPTQQ    +P    PG  SP     PGP  T    PGP    +   GP
Sbjct: 401 PAQQPGPAK--PPTQQVGTPKPLAQQPGLQSPAKA--PGPTKTPVQQPGPGKIPAQQAGP 456

Query: 62  --VAAAGSGLRRGAEGILAPQPPPPQQ------HQERPGAAAIGSARGQSTGKGPPQSP 112
              +A  +G  +    +  P  PPPQQ        ++PG+A   S +  ST K PPQ P
Sbjct: 457 GKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGST-KPPPQQP 514



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 39/119 (32%), Positives = 45/119 (37%), Gaps = 30/119 (25%)

Query: 6   PLQQPSQPQQPPPTQQAVARRPPGGTSPP--NGGLPGPLA----TSAAPPGPPAAASPCL 59
           P+QQP+ P +PP  Q    +  PG   PP    GL  PLA    T   P  PP    P  
Sbjct: 305 PIQQPT-PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363

Query: 60  GPVAAAGSGLRRGAEGILAPQPPPPQQ------HQERPGAAAIGSARGQSTGKGPPQSP 112
            P               L P  PP QQ        E+PG  A+    G   GK P Q P
Sbjct: 364 QP---------------LGPAKPPAQQTGSEKPSSEQPGPKALAQPPG--VGKTPAQQP 405



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 34/101 (33%), Positives = 41/101 (40%), Gaps = 16/101 (15%)

Query: 3   KPQPLQQPSQPQQPPPTQQAVARRP---PGGTSPPNGGLPGPLATSAAPPGPPAAASPCL 59
           KP P QQP  P +PPP Q   A+ P   PG T PP    PGP   S   PG  +   P  
Sbjct: 478 KPPP-QQPG-PAKPPPQQPGSAKPPSQQPGSTKPPPQQ-PGPAKPSPQQPG--STKPPSQ 532

Query: 60  GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSAR 100
            P +A  S  +        P P  P   Q     +  GS +
Sbjct: 533 QPGSAKPSAQQ--------PSPAKPSAQQSTKPVSQTGSGK 565



 Score = 37.7 bits (86), Expect = 0.058
 Identities = 31/83 (37%), Positives = 38/83 (45%), Gaps = 8/83 (9%)

Query: 6   PLQQPSQPQQPPPTQQAVAR---RPPGGTSPPNGGLPGPLATSAAPPGP-PAAASPCLGP 61
           P QQP   + PPP Q   A+   + PG T PP+   PG    SA  P P   +A     P
Sbjct: 500 PSQQPGSTK-PPPQQPGPAKPSPQQPGSTKPPS-QQPGSAKPSAQQPSPAKPSAQQSTKP 557

Query: 62  VAAAGSG--LRRGAEGILAPQPP 82
           V+  GSG  L+       A QPP
Sbjct: 558 VSQTGSGKPLQPPTVSPSAKQPP 580



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 36/112 (32%), Positives = 45/112 (40%), Gaps = 13/112 (11%)

Query: 6   PLQQPSQ---PQQPPPTQQAVARRPP--GGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
           P + PSQ   P +PPP Q   A+ PP   G++ P    PG        PG PA  SP   
Sbjct: 466 PTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPG-PAKPSP-QQ 523

Query: 61  PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
           P +      + G+    A QP P      +P A        Q TG G P  P
Sbjct: 524 PGSTKPPSQQPGSAKPSAQQPSP-----AKPSAQQSTKPVSQ-TGSGKPLQP 569



 Score = 35.4 bits (80), Expect = 0.29
 Identities = 34/114 (29%), Positives = 46/114 (40%), Gaps = 12/114 (10%)

Query: 4   PQPLQQPSQPQQPP--PTQQA----VARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASP 57
           P P + P Q   P   P QQA     + +  G T PP+  LPGP       PGP  A  P
Sbjct: 434 PGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ-LPGPAKPPPQQPGP--AKPP 490

Query: 58  CLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111
              P +A     + G+      QP P +   ++PG+    S   Q  G   P +
Sbjct: 491 PQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS---QQPGSAKPSA 541



 Score = 35.4 bits (80), Expect = 0.29
 Identities = 61/265 (23%), Positives = 101/265 (38%), Gaps = 51/265 (19%)

Query: 390  SSPGPGSEARGINGGPSRMSP--KAQRPLRGAKTLS-SPSNRPSGETSVPPP---PAVGR 443
            S PGP SE++G      ++ P  K + P +    +S  P  +P  + S  PP   P  G+
Sbjct: 832  SHPGPSSESKG----QKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQ 887

Query: 444  MYPP--RSPK-------------SAAPAPISA-SCPEPPIGSAVPTSSASI-----PVTS 482
              P   +SPK             S   AP S  + P+  +   +    ASI      + S
Sbjct: 888  TVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947

Query: 483  SVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQL 542
            +   PG  S S     +  AP   +  +++ P ++          G+ P      K   +
Sbjct: 948  TAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKS---------TGQAPPAP--AKSIPV 996

Query: 543  EELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGL--LTSEPMGSPVSSKT 600
            ++  K  A  KL+P +          P + + E + K   +     LT+EP  + + +K 
Sbjct: 997  KKETKAPAAEKLEPKAEQA-------PTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKL 1049

Query: 601  ESVSDKEDKPPLAPSGGTEGPEQPP 625
            E     E   PL  +    G + PP
Sbjct: 1050 EKSPKPESTCPLCKTELNIGSKDPP 1074



 Score = 34.7 bits (78), Expect = 0.49
 Identities = 37/128 (28%), Positives = 47/128 (36%), Gaps = 28/128 (21%)

Query: 3   KPQPLQQPSQP--------QQP----PPTQQAVARRPP----GGTSPPNGGLPGPLATSA 46
           +P P + P+QP        QQP    PP Q     +PP    G   PP     G    S+
Sbjct: 325 QPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP-AQQTGSEKPSS 383

Query: 47  APPGPPAAAS-PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTG 105
             PGP A A  P +G   A   G          P  PP QQ       A     +  +  
Sbjct: 384 EQPGPKALAQPPGVGKTPAQQPG----------PAKPPTQQVGTPKPLAQQPGLQSPAKA 433

Query: 106 KGPPQSPV 113
            GP ++PV
Sbjct: 434 PGPTKTPV 441



 Score = 31.2 bits (69), Expect = 5.4
 Identities = 36/138 (26%), Positives = 48/138 (34%), Gaps = 15/138 (10%)

Query: 575  EPKGKEKEVDGLLTSEPMGSPV---------SSKTESVSDKEDKPPLAPSGGTEGPEQPP 625
            E  G+EK    L +  P  S +         SS  +  +     PP  P      P  PP
Sbjct: 2365 ETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPP 2424

Query: 626  PPCPSQTGSPPVGLIKGEDKDEGPVAEQV----KKSTLNPNAKEFNPTKPLLSVNKSTST 681
            PP P  T   P  L K +     PV          +TL   A   +   P+  +   T+ 
Sbjct: 2425 PPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRI--CTTA 2482

Query: 682  PTSPGPRTHSTPSIPVLT 699
            P    P+  S PS  V T
Sbjct: 2483 PPPVPPKPSSIPSGLVFT 2500



 Score = 30.4 bits (67), Expect = 9.2
 Identities = 28/122 (22%), Positives = 53/122 (43%), Gaps = 11/122 (9%)

Query: 533  LQNEQKRFQLEELRKFGAQFKLQP---SSSPENSLDPFPPRILKEEPKGKEKEVDGLLTS 589
            +++E+K+  LEE +      KL P   +S+PE         +LK + +  E++++G +  
Sbjct: 1227 IRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHD----LLKSQVQIAEEKLEGRVAP 1282

Query: 590  EPMGSPVSSKTESVSDKEDKPPLAPSGGTEGP----EQPPPPCPSQTGSPPVGLIKGEDK 645
            + +      +T+        P   P    +      EQP PPC ++      G  K E +
Sbjct: 1283 KTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKE 1342

Query: 646  DE 647
            D+
Sbjct: 1343 DD 1344



 Score = 30.4 bits (67), Expect = 9.2
 Identities = 38/155 (24%), Positives = 57/155 (36%), Gaps = 18/155 (11%)

Query: 534  QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593
            + E K+ +    R  G        SS E  L      +LKE+ K +E E           
Sbjct: 1749 KGESKQQRKARHRPHGPLLPTIEDSSEEEELRE-EEELLKEQEKQREIEQQ--------- 1798

Query: 594  SPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP-CPSQTGSPPVGLIKGEDKDE---GP 649
                 K+ S   K+DK  L      E P+ PP    P +  SP   L +  + +E     
Sbjct: 1799 ---QRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSS 1855

Query: 650  VAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTS 684
             +E       +P   E +P K ++ V K    PT+
Sbjct: 1856 CSEYSPSIESDPEGFEISPEK-IIEVQKVYKLPTA 1889


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 80.9 bits (198), Expect = 6e-15
 Identities = 168/701 (23%), Positives = 242/701 (34%), Gaps = 168/701 (23%)

Query: 375  GLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETS 434
            GL++    G       SP   +   G+    S++S + +R +  A  +S     P G  S
Sbjct: 15   GLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQI--AAVMSRAQGLPKG--S 70

Query: 435  VPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISP 494
            VPP  A        SP       + +S P        P  S   P      DPG     P
Sbjct: 71   VPPAAA-------ESPSMHRKQELDSSHP--------PKQSGRPP------DPG----RP 105

Query: 495  ASPKISLA-PTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKF----G 549
            A P +S +  TD      K PGR+  P  ++        L+  + R  L+E  K     G
Sbjct: 106  AQPGLSKSRTTDTFRSEQKLPGRS--PSTIS--------LKESKSRTDLKEEHKSSMMPG 155

Query: 550  AQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKED- 608
               ++   S+  + ++ F P  L  + +  ++E              ++K + V  KE  
Sbjct: 156  FLSEVNALSAVSSVVNKFNPFDLISDSEASQEE--------------TTKKQKVVQKEQG 201

Query: 609  ------KPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPN 662
                  KPPL         +QPP P P Q G        G D    P+ +     +++  
Sbjct: 202  KPEGIIKPPLQ--------QQPPKPIPKQQG-------PGRD----PLQQDGTPKSISSQ 242

Query: 663  AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722
              E   ++P     K    PT      H+   +P+           Q  +  PQ      
Sbjct: 243  QPEKIKSQP-PGTGKPIQGPTQTPQTDHA--KLPL-----------QRDASRPQTKQADI 288

Query: 723  VQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAAT 782
            V+   + P   S S P  Q    G   +  P   ++ QP  A P  Q +    P  +A  
Sbjct: 289  VRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGH-EKSQPGPAKPPAQPSGLTKP--LAQQ 345

Query: 783  PYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQY 842
            P +   P  P   PG            ++P   P+  + P    +GS           + 
Sbjct: 346  PGTVKPPVQP---PG-----------TTKPPAQPLGPAKPPAQQTGS-----------EK 380

Query: 843  PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAG-QA 901
            PS+EQP P+AL      + P    +  A QP PA  PT      Q   P P+  Q G Q+
Sbjct: 381  PSSEQPGPKAL------AQPPGVGKTPAQQPGPAKPPT-----QQVGTPKPLAQQPGLQS 429

Query: 902  PHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMA 961
            P    G  +  +  PG   G  P+   GP   S Q + P           QLP       
Sbjct: 430  PAKAPGPTKTPVQQPG--PGKIPAQQAGPGKTSAQQTGPTKPP------SQLP------G 475

Query: 962  HVTQAHVQTGITAAPPPHPGAPHPP--QVMLLHPPQSHGGPPQGAVPQSGVPALSASTPS 1019
                   Q G    PP  PG+  PP  Q     PP    GP + +  Q G    S   PS
Sbjct: 476  PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPG----STKPPS 531

Query: 1020 PYPYIGHPQGEQPGQAPGFPGGADDRIP--------PLPPP 1052
              P    P  +QP  +P  P       P        PL PP
Sbjct: 532  QQPGSAKPSAQQP--SPAKPSAQQSTKPVSQTGSGKPLQPP 570



 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 157/690 (22%), Positives = 231/690 (33%), Gaps = 123/690 (17%)

Query: 333  QGSGRESPSLASREGKYIPLPQRVREGPR---GGVRCSSSRGG-------RPGLSSLPPR 382
            Q +G E PS      K +  P  V + P    G  +  + + G       +PGL S P +
Sbjct: 374  QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQS-PAK 432

Query: 383  --GPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGET--SVPPP 438
              GP       PGPG +      GP + S +   P +    L  P+  P  +   + PPP
Sbjct: 433  APGPTKTPVQQPGPG-KIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPP 491

Query: 439  PAVGRMYPP-----------RSPKSAAPAPISASCPEPPI---GSAVPTSSASIPV---- 480
               G   PP           + P  A P+P      +PP    GSA P++    P     
Sbjct: 492  QQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSA 551

Query: 481  ---TSSVSDPGVG------SISPAS--------PK--ISLAPTDVKELSTKEPGRTLEPQ 521
               T  VS  G G      ++SP++        PK    L  T    L   E        
Sbjct: 552  QQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCT 611

Query: 522  ELARIAGKVPGLQNEQKRFQLEELRKFGAQFK------LQP-SSSPENSLDPFP----PR 570
            E       + G        +++E      Q K      L P  SSP+  L   P      
Sbjct: 612  ECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSA 671

Query: 571  ILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEG-----PEQPP 625
            + K  P+ ++       TS    +          + +  PPL       G      +QPP
Sbjct: 672  VSKSSPQPQQ-------TSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724

Query: 626  PPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSP 685
                    +PP       ++D+ PVA+   K       K   PT  L+S + +T+ P  P
Sbjct: 725  EADSLSKPAPPKEPSVPSEQDKAPVADDKPK-----QPKMVKPTTDLVSSSSATTKPDIP 779

Query: 686  GPRTHS------TPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPG 739
              +  S      TP +   +A  S  + P      P      A+  P      +S+  PG
Sbjct: 780  SSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSP--FDSKAIPRPASDSKIISH--PG 835

Query: 740  QQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQP 799
               + +G K   P Q+ +  +P  A   M     A P      P  S  P  P+   GQ 
Sbjct: 836  PSSESKGQKQVDPVQKKE--EPKKAQTKMSPKPDAKP-----MPKGSPTPPGPRPTAGQT 888

Query: 800  AMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQ 859
                  +  P +       QS    L  GS     ++ +    P+  Q T          
Sbjct: 889  VPTPQQSPKPQE-------QSRRFSLNLGS-----ITDAPKSQPTTPQETVTGKLFGFGA 936

Query: 860  SYPHHATQL--HAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPG 917
            S    A+ L   A QP P +      P  Q  AP+P Q    Q P   +GQ         
Sbjct: 937  SIFSQASNLISTAGQPGPHSQSGPGAPMKQ--APAPSQPPTSQGPPKSTGQ--------- 985

Query: 918  ALTGTPPSLPPGPSAQSPQSSFPQPAAVYA 947
            A      S+P     ++P +   +P A  A
Sbjct: 986  APPAPAKSIPVKKETKAPAAEKLEPKAEQA 1015



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 149/691 (21%), Positives = 211/691 (30%), Gaps = 135/691 (19%)

Query: 405  PSRMSPKAQRPLRG-----AKTLSSPSNRPSGETSVPP---PPAVGRMYPPRSPKSAAPA 456
            P +  PK Q P R          S  S +P    S PP    P  G    P++  +  P 
Sbjct: 215  PPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPL 274

Query: 457  PISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGR 516
               AS P+      V   S   P   S S P +   +P  P       +  +    +P  
Sbjct: 275  QRDASRPQTKQADIVRGESVK-PSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP-- 331

Query: 517  TLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEP 576
              +P  L +   + PG    +   Q     K  AQ  L P+  P        P   +  P
Sbjct: 332  PAQPSGLTKPLAQQPG--TVKPPVQPPGTTKPPAQ-PLGPAKPPAQQTGSEKPSSEQPGP 388

Query: 577  KGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPP 636
            K   +      T      P    T+ V   +   PLA   G + P + P P  +    P 
Sbjct: 389  KALAQPPGVGKTPAQQPGPAKPPTQQVGTPK---PLAQQPGLQSPAKAPGPTKTPVQQPG 445

Query: 637  VGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIP 696
             G I  +    G             +A++  PTKP   +         PGP         
Sbjct: 446  PGKIPAQQAGPG-----------KTSAQQTGPTKPPSQL---------PGP--------- 476

Query: 697  VLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRS 756
                           +  P    GPA   PQ    P S   P QQ       GS  P   
Sbjct: 477  ---------------AKPPPQQPGPAKPPPQQ---PGSAKPPSQQ------PGSTKP--- 509

Query: 757  DQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAP 816
               QP  A P  Q   +  PP                    QP   +P A  PS    + 
Sbjct: 510  PPQQPGPAKPSPQQPGSTKPP------------------SQQPGSAKPSAQQPSPAKPSA 551

Query: 817  MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPA 876
               + P   T    P    + S    PSA+QP  Q L  T+      + T+L  H P+ A
Sbjct: 552  QQSTKPVSQTGSGKPLQPPTVS----PSAKQPPSQGLPKTICPLC--NTTELLLHVPEKA 605

Query: 877  TTPTGSQPQSQHAA-----PSPVQHQAGQ----------------APHLGSGQPQQNLYH 915
               T ++ Q+   +     P+P   +  +                AP   S QP+     
Sbjct: 606  NFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKT-A 664

Query: 916  PGALTGTPPSLPPGPSAQSPQ---------SSFPQPAAVYAIHHQQLPHGFTNMAHVTQA 966
            P   T       P P   SP+         S  P+P     +  Q   HG  +       
Sbjct: 665  PVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724

Query: 967  HVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGH 1026
               +    APP  P  P          P +   P Q  + +     +S+S+ +  P I  
Sbjct: 725  EADSLSKPAPPKEPSVPSEQD----KAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS 780

Query: 1027 PQGEQPGQAPGFPGGADDRIPP---LPPPGE 1054
             + +   +    P    D   P    PP GE
Sbjct: 781  SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGE 811



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 99/449 (22%), Positives = 159/449 (35%), Gaps = 78/449 (17%)

Query: 373  RPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGE 432
            +P L + P      +  SSP P   +   +  P +   KA  P +    +  P+   S  
Sbjct: 658  QPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPS 717

Query: 433  TSVPPPPAVGRMYPPRSPKSAA------PAPISASCPEPPIGSAVPTSSASIPVTSSVSD 486
                 PP    +  P  PK  +       AP++   P+ P    V  ++  +  +S+ + 
Sbjct: 718  AKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQP--KMVKPTTDLVSSSSATTK 775

Query: 487  PGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELR 546
            P + S    S         +K  S K P ++  P                      E++ 
Sbjct: 776  PDIPSSKVQSQAEEKTTPPLKTDSAK-PSQSFPPTG--------------------EKVS 814

Query: 547  KFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDK 606
             F ++   +P+S  +    P P      E KG +K+VD +   E    P  ++T+ +S K
Sbjct: 815  PFDSKAIPRPASDSKIISHPGP----SSESKG-QKQVDPVQKKE---EPKKAQTK-MSPK 865

Query: 607  EDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLN----PN 662
             D  P+ P G       P PP P  T    V   +   K +    EQ ++ +LN     +
Sbjct: 866  PDAKPM-PKG------SPTPPGPRPTAGQTVPTPQQSPKPQ----EQSRRFSLNLGSITD 914

Query: 663  AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722
            A +  PT P  +V   T      G    S  S  + TAGQ G +S             P 
Sbjct: 915  APKSQPTTPQETV---TGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG-------APM 964

Query: 723  VQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPAS---------APPMMQAAAA 773
             QAP     P S   P   G+   A     P + +   PA+         AP + +    
Sbjct: 965  KQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETE 1024

Query: 774  AGPPLV------AATPYSSYIPYNPQQFP 796
              PP +       A P  + +P   ++ P
Sbjct: 1025 KKPPPIKDSKSLTAEPQKAVLPTKLEKSP 1053



 Score = 51.2 bits (121), Expect = 5e-06
 Identities = 42/119 (35%), Positives = 53/119 (44%), Gaps = 17/119 (14%)

Query: 6   PLQQPSQPQQPPPTQQAVARRP----PGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGP 61
           P QQP   +  PPTQQ    +P    PG  SP     PGP  T    PGP    +   GP
Sbjct: 401 PAQQPGPAK--PPTQQVGTPKPLAQQPGLQSPAKA--PGPTKTPVQQPGPGKIPAQQAGP 456

Query: 62  --VAAAGSGLRRGAEGILAPQPPPPQQ------HQERPGAAAIGSARGQSTGKGPPQSP 112
              +A  +G  +    +  P  PPPQQ        ++PG+A   S +  ST K PPQ P
Sbjct: 457 GKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGST-KPPPQQP 514



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 39/119 (32%), Positives = 45/119 (37%), Gaps = 30/119 (25%)

Query: 6   PLQQPSQPQQPPPTQQAVARRPPGGTSPP--NGGLPGPLA----TSAAPPGPPAAASPCL 59
           P+QQP+ P +PP  Q    +  PG   PP    GL  PLA    T   P  PP    P  
Sbjct: 305 PIQQPT-PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA 363

Query: 60  GPVAAAGSGLRRGAEGILAPQPPPPQQ------HQERPGAAAIGSARGQSTGKGPPQSP 112
            P               L P  PP QQ        E+PG  A+    G   GK P Q P
Sbjct: 364 QP---------------LGPAKPPAQQTGSEKPSSEQPGPKALAQPPG--VGKTPAQQP 405



 Score = 39.3 bits (90), Expect = 0.020
 Identities = 34/101 (33%), Positives = 41/101 (40%), Gaps = 16/101 (15%)

Query: 3   KPQPLQQPSQPQQPPPTQQAVARRP---PGGTSPPNGGLPGPLATSAAPPGPPAAASPCL 59
           KP P QQP  P +PPP Q   A+ P   PG T PP    PGP   S   PG  +   P  
Sbjct: 478 KPPP-QQPG-PAKPPPQQPGSAKPPSQQPGSTKPPPQQ-PGPAKPSPQQPG--STKPPSQ 532

Query: 60  GPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSAR 100
            P +A  S  +        P P  P   Q     +  GS +
Sbjct: 533 QPGSAKPSAQQ--------PSPAKPSAQQSTKPVSQTGSGK 565



 Score = 37.7 bits (86), Expect = 0.058
 Identities = 31/83 (37%), Positives = 38/83 (45%), Gaps = 8/83 (9%)

Query: 6   PLQQPSQPQQPPPTQQAVAR---RPPGGTSPPNGGLPGPLATSAAPPGP-PAAASPCLGP 61
           P QQP   + PPP Q   A+   + PG T PP+   PG    SA  P P   +A     P
Sbjct: 500 PSQQPGSTK-PPPQQPGPAKPSPQQPGSTKPPS-QQPGSAKPSAQQPSPAKPSAQQSTKP 557

Query: 62  VAAAGSG--LRRGAEGILAPQPP 82
           V+  GSG  L+       A QPP
Sbjct: 558 VSQTGSGKPLQPPTVSPSAKQPP 580



 Score = 36.6 bits (83), Expect = 0.13
 Identities = 36/112 (32%), Positives = 45/112 (40%), Gaps = 13/112 (11%)

Query: 6   PLQQPSQ---PQQPPPTQQAVARRPP--GGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
           P + PSQ   P +PPP Q   A+ PP   G++ P    PG        PG PA  SP   
Sbjct: 466 PTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPG-PAKPSP-QQ 523

Query: 61  PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
           P +      + G+    A QP P      +P A        Q TG G P  P
Sbjct: 524 PGSTKPPSQQPGSAKPSAQQPSP-----AKPSAQQSTKPVSQ-TGSGKPLQP 569



 Score = 35.4 bits (80), Expect = 0.29
 Identities = 34/114 (29%), Positives = 46/114 (40%), Gaps = 12/114 (10%)

Query: 4   PQPLQQPSQPQQPP--PTQQA----VARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASP 57
           P P + P Q   P   P QQA     + +  G T PP+  LPGP       PGP  A  P
Sbjct: 434 PGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQ-LPGPAKPPPQQPGP--AKPP 490

Query: 58  CLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111
              P +A     + G+      QP P +   ++PG+    S   Q  G   P +
Sbjct: 491 PQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS---QQPGSAKPSA 541



 Score = 35.4 bits (80), Expect = 0.29
 Identities = 61/265 (23%), Positives = 101/265 (38%), Gaps = 51/265 (19%)

Query: 390  SSPGPGSEARGINGGPSRMSP--KAQRPLRGAKTLS-SPSNRPSGETSVPPP---PAVGR 443
            S PGP SE++G      ++ P  K + P +    +S  P  +P  + S  PP   P  G+
Sbjct: 832  SHPGPSSESKG----QKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQ 887

Query: 444  MYPP--RSPK-------------SAAPAPISA-SCPEPPIGSAVPTSSASI-----PVTS 482
              P   +SPK             S   AP S  + P+  +   +    ASI      + S
Sbjct: 888  TVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIS 947

Query: 483  SVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQL 542
            +   PG  S S     +  AP   +  +++ P ++          G+ P      K   +
Sbjct: 948  TAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKS---------TGQAPPAP--AKSIPV 996

Query: 543  EELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGL--LTSEPMGSPVSSKT 600
            ++  K  A  KL+P +          P + + E + K   +     LT+EP  + + +K 
Sbjct: 997  KKETKAPAAEKLEPKAEQA-------PTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKL 1049

Query: 601  ESVSDKEDKPPLAPSGGTEGPEQPP 625
            E     E   PL  +    G + PP
Sbjct: 1050 EKSPKPESTCPLCKTELNIGSKDPP 1074



 Score = 34.7 bits (78), Expect = 0.49
 Identities = 37/128 (28%), Positives = 47/128 (36%), Gaps = 28/128 (21%)

Query: 3   KPQPLQQPSQP--------QQP----PPTQQAVARRPP----GGTSPPNGGLPGPLATSA 46
           +P P + P+QP        QQP    PP Q     +PP    G   PP     G    S+
Sbjct: 325 QPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP-AQQTGSEKPSS 383

Query: 47  APPGPPAAAS-PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTG 105
             PGP A A  P +G   A   G          P  PP QQ       A     +  +  
Sbjct: 384 EQPGPKALAQPPGVGKTPAQQPG----------PAKPPTQQVGTPKPLAQQPGLQSPAKA 433

Query: 106 KGPPQSPV 113
            GP ++PV
Sbjct: 434 PGPTKTPV 441



 Score = 31.2 bits (69), Expect = 5.4
 Identities = 36/138 (26%), Positives = 48/138 (34%), Gaps = 15/138 (10%)

Query: 575  EPKGKEKEVDGLLTSEPMGSPV---------SSKTESVSDKEDKPPLAPSGGTEGPEQPP 625
            E  G+EK    L +  P  S +         SS  +  +     PP  P      P  PP
Sbjct: 2365 ETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPP 2424

Query: 626  PPCPSQTGSPPVGLIKGEDKDEGPVAEQV----KKSTLNPNAKEFNPTKPLLSVNKSTST 681
            PP P  T   P  L K +     PV          +TL   A   +   P+  +   T+ 
Sbjct: 2425 PPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRI--CTTA 2482

Query: 682  PTSPGPRTHSTPSIPVLT 699
            P    P+  S PS  V T
Sbjct: 2483 PPPVPPKPSSIPSGLVFT 2500



 Score = 30.4 bits (67), Expect = 9.2
 Identities = 28/122 (22%), Positives = 53/122 (43%), Gaps = 11/122 (9%)

Query: 533  LQNEQKRFQLEELRKFGAQFKLQP---SSSPENSLDPFPPRILKEEPKGKEKEVDGLLTS 589
            +++E+K+  LEE +      KL P   +S+PE         +LK + +  E++++G +  
Sbjct: 1227 IRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHD----LLKSQVQIAEEKLEGRVAP 1282

Query: 590  EPMGSPVSSKTESVSDKEDKPPLAPSGGTEGP----EQPPPPCPSQTGSPPVGLIKGEDK 645
            + +      +T+        P   P    +      EQP PPC ++      G  K E +
Sbjct: 1283 KTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKE 1342

Query: 646  DE 647
            D+
Sbjct: 1343 DD 1344



 Score = 30.4 bits (67), Expect = 9.2
 Identities = 38/155 (24%), Positives = 57/155 (36%), Gaps = 18/155 (11%)

Query: 534  QNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMG 593
            + E K+ +    R  G        SS E  L      +LKE+ K +E E           
Sbjct: 1749 KGESKQQRKARHRPHGPLLPTIEDSSEEEELRE-EEELLKEQEKQREIEQQ--------- 1798

Query: 594  SPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP-CPSQTGSPPVGLIKGEDKDE---GP 649
                 K+ S   K+DK  L      E P+ PP    P +  SP   L +  + +E     
Sbjct: 1799 ---QRKSSSKKSKKDKDELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSS 1855

Query: 650  VAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTS 684
             +E       +P   E +P K ++ V K    PT+
Sbjct: 1856 CSEYSPSIESDPEGFEISPEK-IIEVQKVYKLPTA 1889


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 79.7 bits (195), Expect = 1e-14
 Identities = 120/487 (24%), Positives = 156/487 (32%), Gaps = 116/487 (23%)

Query: 580  EKEVDGLLTSEPMGSPVS--SKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPV 637
            ++E   L+   P G+P    +K +       KP   P  G   P+ PPPP     G PP 
Sbjct: 25   QEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP- 83

Query: 638  GLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPV 697
               +G +K +GP      +       K  +P  P          P  P P+  + P  P 
Sbjct: 84   ---QGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP-------PGKPQGPPPQGGNQPQGPP 133

Query: 698  LTAGQSGLYSPQYISYIPQIHMGPAVQA---PQMYPYPVSNSVPGQQGKYRGAKGSLPPQ 754
               G+            PQ   GP  Q    PQ  P P         GK +G     PPQ
Sbjct: 134  PPPGK------------PQ---GPPPQGGNKPQGPPPP---------GKPQGP----PPQ 165

Query: 755  RSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVF 814
              ++ + + +PP        GPP     P     P  P   PG+P    P      Q   
Sbjct: 166  GDNKSRSSRSPP----GKPQGPP-----PQGGNQPQGPPPPPGKPQGPPPQGGNKPQ--- 213

Query: 815  APMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQ 874
             P     P+    G  PQ    S + + P  +   P        Q  P    +     PQ
Sbjct: 214  GPPPPGKPQ----GPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 269

Query: 875  PATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQS 934
                P G  P  +   P P      ++     G+PQ     P    G  P  PP P  + 
Sbjct: 270  GGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQG----PPPQGGNQPQGPPPPPGK- 324

Query: 935  PQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGA--------PHPP 986
            PQ   PQ                    +  Q     G    PPP  G+        P  P
Sbjct: 325  PQGPPPQGG------------------NKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKP 366

Query: 987  QVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRI 1046
            Q     PPQ  G  PQG  P +G               G+PQ  Q   A G P G     
Sbjct: 367  Q----GPPQQEGNNPQGPPPPAG---------------GNPQQPQAPPA-GQPQG----- 401

Query: 1047 PPLPPPG 1053
            PP PP G
Sbjct: 402  PPRPPQG 408



 Score = 77.4 bits (189), Expect = 7e-14
 Identities = 116/429 (27%), Positives = 135/429 (31%), Gaps = 62/429 (14%)

Query: 650  VAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQ--SGLYS 707
            VA     S  N N        P L        P   G +    PS P    G    G   
Sbjct: 8    VALLALSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQ 67

Query: 708  PQYISYIPQIHMGPAVQA---PQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASA 764
            PQ     P    GP  Q    PQ  P P         GK +G     PPQ      P S 
Sbjct: 68   PQGPPPPPGKPQGPPPQGGNKPQGPPPP---------GKPQGP----PPQGDKSRSPRSP 114

Query: 765  PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRM 824
            P   Q     GPP     P     P  P   PG+P    P      Q    P     P+ 
Sbjct: 115  PGKPQ-----GPP-----PQGGNQPQGPPPPPGKPQGPPPQGGNKPQ---GPPPPGKPQ- 160

Query: 825  LTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQP 884
               G  PQ    S + + P  +   P        Q  P    +     PQ    P G  P
Sbjct: 161  ---GPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 217

Query: 885  QSQHAAPSPVQHQAGQA-----------PHLGSGQPQQNLYHPGALTGTPP---SLPPGP 930
              +   P P      Q+           P  G  QPQ     PG   G PP   + P GP
Sbjct: 218  PGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP 277

Query: 931  SAQS-PQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVM 989
                 PQ   P P         + P G          +   G    PPP PG P  P   
Sbjct: 278  PPPGKPQG--PPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQG----PPPPPGKPQGPPPQ 331

Query: 990  LLHPPQSHGGP--PQGAVPQSGVPALSASTPSPYPYIGHPQ--GEQPGQAPGFPGGADDR 1045
              + PQ    P  PQG  PQ G  + SA +P   P  G PQ  G  P Q P  P G + +
Sbjct: 332  GGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQ-GPPQQEGNNP-QGPPPPAGGNPQ 389

Query: 1046 IPPLPPPGE 1054
             P  PP G+
Sbjct: 390  QPQAPPAGQ 398



 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 102/393 (25%), Positives = 128/393 (32%), Gaps = 67/393 (17%)

Query: 555 QPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSS-KTESVSDKEDKPPLA 613
           QP   P     P P +     P+G  K        +P G P    K+ S      KP   
Sbjct: 67  QPQGPP-----PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGP 121

Query: 614 PSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLL 673
           P  G   P+ PPPP     G PP    +G +K +GP           P  K   P  P  
Sbjct: 122 PPQGGNQPQGPPPPPGKPQGPPP----QGGNKPQGP----------PPPGKPQGP--PPQ 165

Query: 674 SVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQA---PQMYP 730
             NKS S+ + PG      P          G   PQ     P    GP  Q    PQ  P
Sbjct: 166 GDNKSRSSRSPPGKPQGPPP---------QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 216

Query: 731 YPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPY 790
            P         GK +G     PPQ  ++ Q A +PP        GPP     P     P 
Sbjct: 217 PP---------GKPQGP----PPQGDNKSQSARSPP----GKPQGPP-----PQGGNQPQ 254

Query: 791 NPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTP 850
            P   PG+P    P      Q    P     P+    G  PQ    S + + P  +   P
Sbjct: 255 GPPPPPGKPQGPPPQGGNKPQ---GPPPPGKPQ----GPPPQGGSKSRSSRSPPGKPQGP 307

Query: 851 QALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQ 910
                   Q  P    +     PQ    P G  P  +   P P      ++     G+PQ
Sbjct: 308 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQ 367

Query: 911 QNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPA 943
                P    G  P  PP P+  +PQ     PA
Sbjct: 368 ----GPPQQEGNNPQGPPPPAGGNPQQPQAPPA 396



 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 109/435 (25%), Positives = 140/435 (32%), Gaps = 57/435 (13%)

Query: 335 SGRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGP 394
           S  ESPSL +   +  P PQ   + P+G         G P      P+GP        GP
Sbjct: 24  SQEESPSLIAGNPQGAP-PQGGNK-PQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 81

Query: 395 GSEARGINGGPSRMSPKAQRPLRGAKTLS--SPSNRPSGET--------SVPPPPAVGRM 444
             +      GP         P +G K+ S  SP  +P G            PPPP   + 
Sbjct: 82  PPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 141

Query: 445 YPPRSP-KSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAP 503
            PP+   K   P P       PP G     SS S P       P  G+     P     P
Sbjct: 142 PPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKP 201

Query: 504 TDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFG--AQFKLQPSSSPE 561
                    +P     P    +  G  P   N+ +  +    +  G   Q   QP   P 
Sbjct: 202 QGPPPQGGNKP---QGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPP- 257

Query: 562 NSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPV--SSKTESVSDKEDKPPLAPSGGTE 619
               P P +     P+G  K        +P G P    SK+ S      KP   P  G  
Sbjct: 258 ----PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGN 313

Query: 620 GPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKST 679
            P+ PPPP     G PP    +G +K +GP                  P KP        
Sbjct: 314 QPQGPPPPPGKPQGPPP----QGGNKPQGPPP----------------PGKP-------Q 346

Query: 680 STPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPG 739
             P   G ++ S  S P    G      PQ     PQ    PA   PQ    P +    G
Sbjct: 347 GPPPQGGSKSRSARSPPGKPQG-----PPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQG 401

Query: 740 QQGKYRGAKGSLPPQ 754
                +G + S PPQ
Sbjct: 402 PPRPPQGGRPSRPPQ 416



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 104/431 (24%), Positives = 134/431 (31%), Gaps = 57/431 (13%)

Query: 394 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSA 453
           P   A    G P +   K Q P         P  +   +   PPPP      PP    + 
Sbjct: 29  PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 88

Query: 454 APAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKE 513
              P     P+ P      + S   P       P  G   P  P     P   K      
Sbjct: 89  PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP----PPPPGKPQGPPP 144

Query: 514 PG--RTLEPQELARIAGKVPGLQNEQKRFQLEELRKFG--AQFKLQPSSSPENSLDPFPP 569
            G  +   P    +  G  P   N+ +  +    +  G   Q   QP   P     P P 
Sbjct: 145 QGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPP-----PPPG 199

Query: 570 RILKEEPKGKEKEVDGLLTSEPMGSPV--SSKTESVSDKEDKPPLAPSGGTEGPEQPPPP 627
           +     P+G  K        +P G P    +K++S      KP   P  G   P+ PPPP
Sbjct: 200 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPP 259

Query: 628 CPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGP 687
                G PP    +G +K +GP           P  K   P  P    +KS S+ + PG 
Sbjct: 260 PGKPQGPPP----QGGNKPQGP----------PPPGKPQGP--PPQGGSKSRSSRSPPGK 303

Query: 688 RTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQA---PQMYPYPVSNSVPGQQGKY 744
                P          G   PQ     P    GP  Q    PQ  P P     P  QG  
Sbjct: 304 PQGPPP---------QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGS 354

Query: 745 RGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFP-GQP--AM 801
           +      PP +         PP  +     GPP     P +   P  PQ  P GQP    
Sbjct: 355 KSRSARSPPGK------PQGPPQQEGNNPQGPP-----PPAGGNPQQPQAPPAGQPQGPP 403

Query: 802 MQPMAHYPSQP 812
             P    PS+P
Sbjct: 404 RPPQGGRPSRP 414



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 42/131 (32%), Positives = 49/131 (37%), Gaps = 25/131 (19%)

Query: 3   KPQPLQQPSQPQQPPP---TQQAVARRPPG--------GTSPPNGGLPGPLATSAAPP-- 49
           KPQ    P +PQ PPP    +   AR PPG        G + P G  P P      PP  
Sbjct: 211 KPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 270

Query: 50  -----GPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQE------RPGAAAIGS 98
                GPP    P  GP    GS  R        PQ PPPQ   +       PG      
Sbjct: 271 GNKPQGPPPPGKP-QGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 329

Query: 99  ARGQSTGKGPP 109
            +G +  +GPP
Sbjct: 330 PQGGNKPQGPP 340



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 42/131 (32%), Positives = 50/131 (38%), Gaps = 22/131 (16%)

Query: 3   KPQPLQQPSQPQQPPP---TQQAVARRPPG--------GTSPPNGGLPGPLATSAAPP-- 49
           KPQ    P +PQ PPP   ++   +R PPG        G + P G  P P      PP  
Sbjct: 273 KPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 332

Query: 50  -----GPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQ---HQERPGAAAIGSARG 101
                GPP    P  GP    GS  R        PQ PP Q+    Q  P  A     + 
Sbjct: 333 GNKPQGPPPPGKP-QGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQP 391

Query: 102 QSTGKGPPQSP 112
           Q+   G PQ P
Sbjct: 392 QAPPAGQPQGP 402



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 40/133 (30%), Positives = 51/133 (38%), Gaps = 19/133 (14%)

Query: 3   KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLP-----GP-------LATSAAP 48
           KPQ  P Q  +QPQ PPP        PP G + P G  P     GP         ++ +P
Sbjct: 179 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSP 238

Query: 49  PG-----PPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQS 103
           PG     PP   +   GP    G       +G   PQ PPP    + P       +R   
Sbjct: 239 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSR 298

Query: 104 TGKGPPQSPVFEG 116
           +  G PQ P  +G
Sbjct: 299 SPPGKPQGPPPQG 311



 Score = 47.4 bits (111), Expect = 7e-05
 Identities = 40/133 (30%), Positives = 51/133 (38%), Gaps = 19/133 (14%)

Query: 3   KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLP-----GP-------LATSAAP 48
           KPQ  P Q  +QPQ PPP        PP G + P G  P     GP         +S +P
Sbjct: 117 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSP 176

Query: 49  PG-----PPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQS 103
           PG     PP   +   GP    G       +G   PQ PPP    + P       ++   
Sbjct: 177 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSAR 236

Query: 104 TGKGPPQSPVFEG 116
           +  G PQ P  +G
Sbjct: 237 SPPGKPQGPPPQG 249



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 45/131 (34%), Positives = 54/131 (41%), Gaps = 23/131 (17%)

Query: 3   KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLP-----GP-------LATSAAP 48
           KPQ  P Q  +QPQ PPP        PP G + P G  P     GP         +S +P
Sbjct: 241 KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP 300

Query: 49  PG-----PPAAASPCLGPVAAAGSGLRRGAEGILAPQ-PPPPQQHQERP--GAAAIGSAR 100
           PG     PP   +   GP    G       +G   PQ PPPP + Q  P  G +   SAR
Sbjct: 301 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSAR 360

Query: 101 G-QSTGKGPPQ 110
                 +GPPQ
Sbjct: 361 SPPGKPQGPPQ 371



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 35/109 (32%), Positives = 42/109 (38%), Gaps = 12/109 (11%)

Query: 3   KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
           KPQ  P Q  +QPQ PPP        PP G + P G  P        P GPP        
Sbjct: 56  KPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP-----PGKPQGPPPQGDKSRS 110

Query: 61  PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109
           P +  G       +G   PQ PPP      PG       +G +  +GPP
Sbjct: 111 PRSPPGKPQGPPPQGGNQPQGPPPP-----PGKPQGPPPQGGNKPQGPP 154



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 37/117 (31%), Positives = 47/117 (40%), Gaps = 16/117 (13%)

Query: 3   KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPG-----PPAAA 55
           KPQ  P Q  ++PQ PPP       +P G   PP GG      +S +PPG     PP   
Sbjct: 262 KPQGPPPQGGNKPQGPPP-----PGKPQG--PPPQGG--SKSRSSRSPPGKPQGPPPQGG 312

Query: 56  SPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQSP 112
           +   GP    G       +G   PQ PPP    + P       +R   +  G PQ P
Sbjct: 313 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGP 369



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 39/130 (30%), Positives = 47/130 (36%), Gaps = 24/130 (18%)

Query: 3   KPQPLQQPSQPQQPPPT--QQAVARRPPG--------GTSPPNGGLPGPLATSAAPP--- 49
           KPQ    P +PQ PPP   +    R PPG        G + P G  P P      PP   
Sbjct: 88  KPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 147

Query: 50  ----GPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQE------RPGAAAIGSA 99
               GPP    P  GP     +  R        PQ PPPQ   +       PG       
Sbjct: 148 NKPQGPPPPGKP-QGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 206

Query: 100 RGQSTGKGPP 109
           +G +  +GPP
Sbjct: 207 QGGNKPQGPP 216



 Score = 37.0 bits (84), Expect = 0.099
 Identities = 32/105 (30%), Positives = 39/105 (37%), Gaps = 9/105 (8%)

Query: 13  PQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRG 72
           PQ  PP      + PP     P G  P P   +  P GPP       GP    G    +G
Sbjct: 36  PQGAPPQGGNKPQGPPSPPGKPQG--PPPQGGN-QPQGPPPPPGKPQGP-PPQGGNKPQG 91

Query: 73  AEGILAPQPPPPQQHQER-----PGAAAIGSARGQSTGKGPPQSP 112
                 PQ PPPQ  + R     PG       +G +  +GPP  P
Sbjct: 92  PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP 136



 Score = 31.6 bits (70), Expect = 4.2
 Identities = 21/61 (34%), Positives = 24/61 (39%), Gaps = 12/61 (19%)

Query: 3   KPQ--PLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
           KPQ  P Q+ + PQ PP         PP G +P     P P      PP PP    P   
Sbjct: 365 KPQGPPQQEGNNPQGPP---------PPAGGNPQQPQAP-PAGQPQGPPRPPQGGRPSRP 414

Query: 61  P 61
           P
Sbjct: 415 P 415


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 78.2 bits (191), Expect = 4e-14
 Identities = 147/626 (23%), Positives = 209/626 (33%), Gaps = 116/626 (18%)

Query: 490  GSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEEL---R 546
            G  SP    +S + +D K   +++  +    +E +       G   E    + EE    +
Sbjct: 31   GRASPGG--VSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPK 88

Query: 547  KFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD--GLLTSEPMGSPVSSKTESVS 604
            K   + +L    SP + LD    R L ++     +++D     TS  + SP S + +S S
Sbjct: 89   KTKTEQELPRPQSPSD-LDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDS 147

Query: 605  DKEDKPPLAPSGGTEGPEQP--PPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPN 662
                      SG ++GP +P  PPP    +  PP      +     P A      ++ P 
Sbjct: 148  S---------SGLSQGPARPYHPPPLFPPSPQPP------DSTPRQPEASFEPHPSVTPT 192

Query: 663  AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722
                    P   + ++      P P+ +   +  VL+    G       S +   + G  
Sbjct: 193  GYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQ 252

Query: 723  VQAPQMYPYPVSNSVPGQQGKYR----------GAKGSLPPQRSDQHQPASAPPMMQAA- 771
               P     P+S S  G  G             G   S PP  +  H   + PP      
Sbjct: 253  HPPPTT---PISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRP 309

Query: 772  ---AAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRML--- 825
               A+A PP + A P        P   P   AM Q M   P  P   P L  +P  L   
Sbjct: 310  LNNASASPPGLGAQPL-------PGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPA 362

Query: 826  -------------TSGSHPQAIVSSSTPQYPSAEQPTP--QALYATVHQSYPHHATQLHA 870
                         +S S   A  SSS+    S+  P P  QAL      SYPH       
Sbjct: 363  SSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQAL-----PSYPHSF----- 412

Query: 871  HQPQPATTPTGSQPQ--SQHAAPSPVQHQAGQAPHLGSGQPQQNLY-HPGALTGTPPSLP 927
              P P +    +QP   +Q + PS      G  P    G+   N   HPG          
Sbjct: 413  --PPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPG---------- 460

Query: 928  PGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQ 987
            P P +   QS+   P + +  HHQQ            Q   Q    + PPP    PHP +
Sbjct: 461  PFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLE 520

Query: 988  VMLLH------------------PPQSHGGPPQGAVPQS-----GVPALSASTPSPYPYI 1024
                H                  P  +H  PP   V  S     G P  S+S  S     
Sbjct: 521  GGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQ 580

Query: 1025 GHPQGEQPGQAPGFPGGADDRIPPLP 1050
            G      P  + G P GA    PP+P
Sbjct: 581  GSYPCSHPSPSQG-PQGAPYPFPPVP 605



 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 165/706 (23%), Positives = 230/706 (32%), Gaps = 108/706 (15%)

Query: 391  SPGPGSEARGIN----GGPSRMSP--KAQRPLRGAKTL-----SSPSNRPSGETSVPPPP 439
            +PGP  E R       GG S  S   KA++  + AK       S+P     G +      
Sbjct: 20   APGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISES 79

Query: 440  AVGRMYPPRSPKSAA--PAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPA-- 495
                   P+  K+    P P S S  +   G ++    +S P      D    S SP+  
Sbjct: 80   ESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDI---DQDNRSTSPSIY 136

Query: 496  SPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQ 555
            SP      +D     ++ P R   P  L   + + P     Q     E            
Sbjct: 137  SPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHA 196

Query: 556  PSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSD----KEDKPP 611
            P   P + +   PP      P+       G+L+  PMG        SV      K+  PP
Sbjct: 197  PMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPP 256

Query: 612  LAP-SGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTK 670
              P S  + G    PP  P  T   PVG   G +    P        T N       P  
Sbjct: 257  TTPISVSSSGASGAPPTKPPTT---PVG---GGNLPSAPPPANFPHVTPN-----LPPPP 305

Query: 671  PLLSVNKSTSTPTSPG--PRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQ-APQ 727
             L  +N ++++P   G  P     PS   +  G  GL         P    GP +  +P 
Sbjct: 306  ALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLP--------PGPEKGPTLAPSPH 357

Query: 728  MYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSY 787
              P P S+S P             PP R      +S+     +++++     +  P S  
Sbjct: 358  SLP-PASSSAPA------------PPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQA 404

Query: 788  IPYNPQQFPGQPAM----MQPMAHYPSQPVFAPMLQSNP------RMLT-SGSHPQAIVS 836
            +P  P  FP   ++      P    PS P  A   Q  P      R+L  S +HP     
Sbjct: 405  LPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPP 464

Query: 837  SSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQ- 895
            S+  Q  S   P P + +   HQ       Q    Q Q       S P    A P P++ 
Sbjct: 465  STGAQ--STAHP-PVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEG 521

Query: 896  ------HQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQ--PAAVYA 947
                  H    +P LGS +P    Y PG     P  LPP  S  S   + P   P +  +
Sbjct: 522  GSSHHAHPYAMSPSLGSLRP----YPPG-----PAHLPPPHSQVSYSQAGPNGPPVSSSS 572

Query: 948  IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQ 1007
                    G    +H + +    G   AP P P  P                    +   
Sbjct: 573  NSSSSTSQGSYPCSHPSPSQ---GPQGAPYPFPPVPTVTT---------------SSATL 614

Query: 1008 SGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRIPPLPPPG 1053
            S V A  AS+P+ Y     P     G+    PG      PP   PG
Sbjct: 615  STVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPG 660



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 146/633 (23%), Positives = 197/633 (31%), Gaps = 114/633 (18%)

Query: 371 GGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS 430
           GG  G+ S PP GP        G  S   G NGG     P     +  +    +P  +P 
Sbjct: 222 GGTGGVLSGPPMGP-----KGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKP- 275

Query: 431 GETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVG 490
                 P   VG    P +P  A    ++ + P PP    +  +SAS P   +   PG  
Sbjct: 276 ------PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPG-- 327

Query: 491 SISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGA 550
              P+   +      +     K P     P  L   +   P       RF         A
Sbjct: 328 -HLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPA---PPMRFPYSSSSSSSA 383

Query: 551 QFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKP 610
                 SSS  +S  PFP                  L S P   P              P
Sbjct: 384 AAS-SSSSSSSSSASPFP--------------ASQALPSYPHSFP--------------P 414

Query: 611 PLAPSGGTEGPEQPPPPCPSQT----GSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEF 666
           P + S   + P+   P  PSQ     G PP            P    +  S  +P     
Sbjct: 415 PTSLSVSNQPPKYTQPSLPSQAVWSQGPPP----------PPPYGRLLANSNAHP----- 459

Query: 667 NPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAP 726
            P  P      +   P S     H           Q      Q      Q H       P
Sbjct: 460 GPFPPSTGAQSTAHPPVSTHHHHHQQQQ-------QQQQQQQQQQQQQQQHHGNSGPPPP 512

Query: 727 QMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPP-----MMQAAAAAGPPLVAA 781
             +P+P+          Y     SL   R     PA  PP         A   GPP+ ++
Sbjct: 513 GAFPHPLEGGSSHHAHPY-AMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSS 571

Query: 782 TPYSSYIPYN--PQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSST 839
           +  SS       P   P  P+     A YP  PV  P + ++   L   S   A V+SS 
Sbjct: 572 SNSSSSTSQGSYPCSHP-SPSQGPQGAPYPFPPV--PTVTTSSATL---STVIATVASSP 625

Query: 840 PQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAG 899
             Y +A  P P           P +  +  +       TP G +P       SP   + G
Sbjct: 626 AGYKTASPPGP-----------PPYGKRAPSPGAYKTATPPGYKP------GSPPSFRTG 668

Query: 900 QAP-HLGSGQPQ-QNLYHPGALTGTPPSLPP-GPSAQSPQSSFPQPAAVYAIHHQQLPHG 956
             P + G+  P     + PG+ T  P  LPP GPS      S P P A  A      P  
Sbjct: 669 TPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSG---LPSLPPPPAAPA---SGPPLS 722

Query: 957 FTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVM 989
            T +        +T  +  PP    +P PP+V+
Sbjct: 723 ATQIKQEPAEEYETPESPVPPARSPSP-PPKVV 754



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 131/564 (23%), Positives = 178/564 (31%), Gaps = 123/564 (21%)

Query: 359 GPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNS----SPGPGSEARGINGG---------- 404
           GP+GG   SS  G   G    PP  P  + +S    +P        + GG          
Sbjct: 234 GPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPAN 293

Query: 405 -----PSRMSPKAQRPLRGAKT-------------LSSPSNRPSGETSVPPPPAVGRMYP 446
                P+   P A RPL  A               L SP     G   +PP P  G    
Sbjct: 294 FPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLA 353

Query: 447 PRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDV 506
           P SP S  PA  S+S P PP+           P +SS S     S S +S   S +P   
Sbjct: 354 P-SPHSLPPA--SSSAPAPPM---------RFPYSSSSSSSAAASSSSSSSSSSASPFPA 401

Query: 507 KELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSL-- 564
            +     P     P  L+        + N+  ++    L       +  P   P   L  
Sbjct: 402 SQALPSYPHSFPPPTSLS--------VSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLA 453

Query: 565 ------DPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSS-----KTESVSDKEDKPPLA 613
                  PFPP                  T+ P   PVS+     + +    ++ +    
Sbjct: 454 NSNAHPGPFPP------------STGAQSTAHP---PVSTHHHHHQQQQQQQQQQQQQQQ 498

Query: 614 PSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLL 673
                 G   PPPP     G+ P  L  G      P A      +L P      P  P  
Sbjct: 499 QQQQHHGNSGPPPP-----GAFPHPLEGGSSHHAHPYAMSPSLGSLRP-----YPPGP-- 546

Query: 674 SVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP- 732
                   P S    + + P+ P +++  +   S    SY P  H  P+ Q PQ  PYP 
Sbjct: 547 ---AHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSY-PCSHPSPS-QGPQGAPYPF 601

Query: 733 ------------VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAG----- 775
                       +S  +        G K + PP      + A +P   + A   G     
Sbjct: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS 661

Query: 776 -PPLVAATP---YSSYIPYNPQQF-PGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSH 830
            P     TP     +  P  P  F PG P  + P    P+ P   P L   P    SG  
Sbjct: 662 PPSFRTGTPPGYRGTSPPAGPGTFKPGSPT-VGPGPLPPAGPSGLPSLPPPPAAPASGPP 720

Query: 831 PQAIVSSSTP--QYPSAEQPTPQA 852
             A      P  +Y + E P P A
Sbjct: 721 LSATQIKQEPAEEYETPESPVPPA 744



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 133/590 (22%), Positives = 201/590 (34%), Gaps = 102/590 (17%)

Query: 351  PLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSP 410
            P P   R    G  + ++  G +PG        P      +P PG        GP    P
Sbjct: 636  PPPYGKRAPSPGAYKTATPPGYKPG-------SPPSFRTGTP-PGYRGTSPPAGPGTFKP 687

Query: 411  KAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKS------------AAPAPI 458
             +  P  G   L  P   PSG  S+PPPPA     PP S                +P P 
Sbjct: 688  GS--PTVGPGPL--PPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPP 743

Query: 459  SASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRT- 517
            + S   PP    VP+ ++     +   D G  S   A   +   P +  +L+ K      
Sbjct: 744  ARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSC--ARSDLYFVPLEGSKLAKKRADLVE 801

Query: 518  ---LEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKL-QPSSSPEN--SLDPFPPRI 571
                E ++ AR   +    +  +K  + E+ R+     KL Q   +P    SL P P R 
Sbjct: 802  KVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRP 861

Query: 572  LKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPC--P 629
              E           + T  P   P +    ++S+   +P +   G    P   P     P
Sbjct: 862  PFEPG-------SAVATVPPYLGPDTPALRTLSEYA-RPHVMSPGNRNHPFYVPLGAVDP 913

Query: 630  SQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTS--PGP 687
               G     L   +     P A + ++     + ++    KP   V  S   P    PGP
Sbjct: 914  GLLGYNVPALYSSD-----PAAREREREARERDLRD--RLKPGFEVKPSELEPLHGVPGP 966

Query: 688  RTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQ--APQMYPYPVSNSV-PGQQGKY 744
                 P                        H G A+Q   P ++P+P   S+ P ++ + 
Sbjct: 967  GLDPFPR-----------------------HGGLALQPGPPGLHPFPFHPSLGPLERERL 1003

Query: 745  RGAKG-SLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQ--QFPGQPAM 801
              A G +L P  S   + A+     +  AA G   +A     +  P++ Q         +
Sbjct: 1004 ALAAGPALRPDMSYAERLAAERQHAERVAALGNDPLARLQMLNVTPHHHQHSHIHSHLHL 1063

Query: 802  MQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSY 861
             Q  A + +     P++      L SGSH   I       YP+   P P          +
Sbjct: 1064 HQQDAIHAASASVHPLIDP----LASGSHLTRI------PYPAGTLPNPLL-------PH 1106

Query: 862  PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQ 911
            P H  ++  HQ   A  P    P S  +AP    HQ  QA H  S + Q+
Sbjct: 1107 PLHENEVLRHQLFAA--PYRDLPASL-SAPMSAAHQL-QAMHAQSAELQR 1152



 Score = 40.4 bits (93), Expect = 0.009
 Identities = 68/298 (22%), Positives = 92/298 (30%), Gaps = 41/298 (13%)

Query: 385 HHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRM 444
           HH ++  P PG+    + GG S  +     P   + +L S    P G   +PPP      
Sbjct: 503 HHGNSGPPPPGAFPHPLEGGSSHHA----HPYAMSPSLGSLRPYPPGPAHLPPP------ 552

Query: 445 YPPRSPKSAAP--APISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLA 502
           +   S   A P   P+S+S       S+  TS  S P +      G        P +   
Sbjct: 553 HSQVSYSQAGPNGPPVSSSS-----NSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTV 607

Query: 503 PTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN 562
            T    LST     T+            PG     KR       K       +P S    
Sbjct: 608 TTSSATLSTVIA--TVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS---- 661

Query: 563 SLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPE 622
                PP      P G         TS P G                PP  PSG    P 
Sbjct: 662 -----PPSFRTGTPPGYRG------TSPPAGPGTFKPGSPTVGPGPLPPAGPSGL---PS 707

Query: 623 QPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTS 680
            PPPP    +G P    +      + P  E     +  P A+  +P   ++ V    S
Sbjct: 708 LPPPPAAPASGPP----LSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHAS 761



 Score = 37.0 bits (84), Expect = 0.099
 Identities = 31/95 (32%), Positives = 37/95 (38%), Gaps = 18/95 (18%)

Query: 12  QPQQPPPTQQAVARRPPG--GTSPPNGGL----------PGPL---ATSAAPPGPPAAAS 56
           +P  PP  +      PPG  GTSPP G            PGPL     S  P  PP  A+
Sbjct: 658 KPGSPPSFRTGT---PPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAA 714

Query: 57  PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERP 91
           P  GP  +A    +  AE    P+ P P      P
Sbjct: 715 PASGPPLSATQIKQEPAEEYETPESPVPPARSPSP 749



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 22/52 (42%), Positives = 25/52 (48%), Gaps = 6/52 (11%)

Query: 4   PQPLQQ--PSQPQQ-PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPP 52
           P P  Q  PS P   PPPT  +V+ +PP  T P    LP     S  PP PP
Sbjct: 398 PFPASQALPSYPHSFPPPTSLSVSNQPPKYTQP---SLPSQAVWSQGPPPPP 446



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 32/104 (30%), Positives = 37/104 (35%), Gaps = 19/104 (18%)

Query: 8   QQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGS 67
           QQ  Q QQ    QQ   +       PP G  P PL   ++    P A SP LG       
Sbjct: 485 QQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGS------ 538

Query: 68  GLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111
                    L P PP P  H   P +    S  G +   GPP S
Sbjct: 539 ---------LRPYPPGP-AHLPPPHSQVSYSQAGPN---GPPVS 569



 Score = 33.9 bits (76), Expect = 0.84
 Identities = 34/113 (30%), Positives = 42/113 (37%), Gaps = 16/113 (14%)

Query: 4   PQPLQQPS-QPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPV 62
           P PL  PS QP    P Q   +  P    +P     P    TS     PP A  P   P 
Sbjct: 161 PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPP--HPQ 218

Query: 63  AAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK--GPPQSPV 113
              G     G  G+L+  P  P+      G  A  S  G + GK   PP +P+
Sbjct: 219 LYPG-----GTGGVLSGPPMGPK------GGGAASSVGGPNGGKQHPPPTTPI 260



 Score = 33.1 bits (74), Expect = 1.4
 Identities = 28/96 (29%), Positives = 31/96 (32%), Gaps = 3/96 (3%)

Query: 14  QQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGA 73
           Q PPPT            +PP      P+     P  PP A  P + P       LR   
Sbjct: 252 QHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLN 311

Query: 74  EGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109
               A   PP    Q  PG      A GQ  G  PP
Sbjct: 312 N---ASASPPGLGAQPLPGHLPSPHAMGQGMGGLPP 344


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 78.2 bits (191), Expect = 4e-14
 Identities = 147/626 (23%), Positives = 209/626 (33%), Gaps = 116/626 (18%)

Query: 490  GSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEEL---R 546
            G  SP    +S + +D K   +++  +    +E +       G   E    + EE    +
Sbjct: 31   GRASPGG--VSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPK 88

Query: 547  KFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVD--GLLTSEPMGSPVSSKTESVS 604
            K   + +L    SP + LD    R L ++     +++D     TS  + SP S + +S S
Sbjct: 89   KTKTEQELPRPQSPSD-LDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDS 147

Query: 605  DKEDKPPLAPSGGTEGPEQP--PPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPN 662
                      SG ++GP +P  PPP    +  PP      +     P A      ++ P 
Sbjct: 148  S---------SGLSQGPARPYHPPPLFPPSPQPP------DSTPRQPEASFEPHPSVTPT 192

Query: 663  AKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPA 722
                    P   + ++      P P+ +   +  VL+    G       S +   + G  
Sbjct: 193  GYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQ 252

Query: 723  VQAPQMYPYPVSNSVPGQQGKYR----------GAKGSLPPQRSDQHQPASAPPMMQAA- 771
               P     P+S S  G  G             G   S PP  +  H   + PP      
Sbjct: 253  HPPPTT---PISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRP 309

Query: 772  ---AAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRML--- 825
               A+A PP + A P        P   P   AM Q M   P  P   P L  +P  L   
Sbjct: 310  LNNASASPPGLGAQPL-------PGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPA 362

Query: 826  -------------TSGSHPQAIVSSSTPQYPSAEQPTP--QALYATVHQSYPHHATQLHA 870
                         +S S   A  SSS+    S+  P P  QAL      SYPH       
Sbjct: 363  SSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQAL-----PSYPHSF----- 412

Query: 871  HQPQPATTPTGSQPQ--SQHAAPSPVQHQAGQAPHLGSGQPQQNLY-HPGALTGTPPSLP 927
              P P +    +QP   +Q + PS      G  P    G+   N   HPG          
Sbjct: 413  --PPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPG---------- 460

Query: 928  PGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQ 987
            P P +   QS+   P + +  HHQQ            Q   Q    + PPP    PHP +
Sbjct: 461  PFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLE 520

Query: 988  VMLLH------------------PPQSHGGPPQGAVPQS-----GVPALSASTPSPYPYI 1024
                H                  P  +H  PP   V  S     G P  S+S  S     
Sbjct: 521  GGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQ 580

Query: 1025 GHPQGEQPGQAPGFPGGADDRIPPLP 1050
            G      P  + G P GA    PP+P
Sbjct: 581  GSYPCSHPSPSQG-PQGAPYPFPPVP 605



 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 165/706 (23%), Positives = 230/706 (32%), Gaps = 108/706 (15%)

Query: 391  SPGPGSEARGIN----GGPSRMSP--KAQRPLRGAKTL-----SSPSNRPSGETSVPPPP 439
            +PGP  E R       GG S  S   KA++  + AK       S+P     G +      
Sbjct: 20   APGPREELRSRGRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISES 79

Query: 440  AVGRMYPPRSPKSAA--PAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPA-- 495
                   P+  K+    P P S S  +   G ++    +S P      D    S SP+  
Sbjct: 80   ESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDI---DQDNRSTSPSIY 136

Query: 496  SPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQ 555
            SP      +D     ++ P R   P  L   + + P     Q     E            
Sbjct: 137  SPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHA 196

Query: 556  PSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSD----KEDKPP 611
            P   P + +   PP      P+       G+L+  PMG        SV      K+  PP
Sbjct: 197  PMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPP 256

Query: 612  LAP-SGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTK 670
              P S  + G    PP  P  T   PVG   G +    P        T N       P  
Sbjct: 257  TTPISVSSSGASGAPPTKPPTT---PVG---GGNLPSAPPPANFPHVTPN-----LPPPP 305

Query: 671  PLLSVNKSTSTPTSPG--PRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQ-APQ 727
             L  +N ++++P   G  P     PS   +  G  GL         P    GP +  +P 
Sbjct: 306  ALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLP--------PGPEKGPTLAPSPH 357

Query: 728  MYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSY 787
              P P S+S P             PP R      +S+     +++++     +  P S  
Sbjct: 358  SLP-PASSSAPA------------PPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQA 404

Query: 788  IPYNPQQFPGQPAM----MQPMAHYPSQPVFAPMLQSNP------RMLT-SGSHPQAIVS 836
            +P  P  FP   ++      P    PS P  A   Q  P      R+L  S +HP     
Sbjct: 405  LPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPP 464

Query: 837  SSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQ- 895
            S+  Q  S   P P + +   HQ       Q    Q Q       S P    A P P++ 
Sbjct: 465  STGAQ--STAHP-PVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEG 521

Query: 896  ------HQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQ--PAAVYA 947
                  H    +P LGS +P    Y PG     P  LPP  S  S   + P   P +  +
Sbjct: 522  GSSHHAHPYAMSPSLGSLRP----YPPG-----PAHLPPPHSQVSYSQAGPNGPPVSSSS 572

Query: 948  IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQ 1007
                    G    +H + +    G   AP P P  P                    +   
Sbjct: 573  NSSSSTSQGSYPCSHPSPSQ---GPQGAPYPFPPVPTVTT---------------SSATL 614

Query: 1008 SGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRIPPLPPPG 1053
            S V A  AS+P+ Y     P     G+    PG      PP   PG
Sbjct: 615  STVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPG 660



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 146/633 (23%), Positives = 197/633 (31%), Gaps = 114/633 (18%)

Query: 371 GGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPS 430
           GG  G+ S PP GP        G  S   G NGG     P     +  +    +P  +P 
Sbjct: 222 GGTGGVLSGPPMGP-----KGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKP- 275

Query: 431 GETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVG 490
                 P   VG    P +P  A    ++ + P PP    +  +SAS P   +   PG  
Sbjct: 276 ------PTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPG-- 327

Query: 491 SISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGA 550
              P+   +      +     K P     P  L   +   P       RF         A
Sbjct: 328 -HLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPA---PPMRFPYSSSSSSSA 383

Query: 551 QFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKP 610
                 SSS  +S  PFP                  L S P   P              P
Sbjct: 384 AAS-SSSSSSSSSASPFP--------------ASQALPSYPHSFP--------------P 414

Query: 611 PLAPSGGTEGPEQPPPPCPSQT----GSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEF 666
           P + S   + P+   P  PSQ     G PP            P    +  S  +P     
Sbjct: 415 PTSLSVSNQPPKYTQPSLPSQAVWSQGPPP----------PPPYGRLLANSNAHP----- 459

Query: 667 NPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAP 726
            P  P      +   P S     H           Q      Q      Q H       P
Sbjct: 460 GPFPPSTGAQSTAHPPVSTHHHHHQQQQ-------QQQQQQQQQQQQQQQHHGNSGPPPP 512

Query: 727 QMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPP-----MMQAAAAAGPPLVAA 781
             +P+P+          Y     SL   R     PA  PP         A   GPP+ ++
Sbjct: 513 GAFPHPLEGGSSHHAHPY-AMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSS 571

Query: 782 TPYSSYIPYN--PQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSST 839
           +  SS       P   P  P+     A YP  PV  P + ++   L   S   A V+SS 
Sbjct: 572 SNSSSSTSQGSYPCSHP-SPSQGPQGAPYPFPPV--PTVTTSSATL---STVIATVASSP 625

Query: 840 PQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAG 899
             Y +A  P P           P +  +  +       TP G +P       SP   + G
Sbjct: 626 AGYKTASPPGP-----------PPYGKRAPSPGAYKTATPPGYKP------GSPPSFRTG 668

Query: 900 QAP-HLGSGQPQ-QNLYHPGALTGTPPSLPP-GPSAQSPQSSFPQPAAVYAIHHQQLPHG 956
             P + G+  P     + PG+ T  P  LPP GPS      S P P A  A      P  
Sbjct: 669 TPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSG---LPSLPPPPAAPA---SGPPLS 722

Query: 957 FTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVM 989
            T +        +T  +  PP    +P PP+V+
Sbjct: 723 ATQIKQEPAEEYETPESPVPPARSPSP-PPKVV 754



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 131/564 (23%), Positives = 178/564 (31%), Gaps = 123/564 (21%)

Query: 359 GPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNS----SPGPGSEARGINGG---------- 404
           GP+GG   SS  G   G    PP  P  + +S    +P        + GG          
Sbjct: 234 GPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPAN 293

Query: 405 -----PSRMSPKAQRPLRGAKT-------------LSSPSNRPSGETSVPPPPAVGRMYP 446
                P+   P A RPL  A               L SP     G   +PP P  G    
Sbjct: 294 FPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLA 353

Query: 447 PRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDV 506
           P SP S  PA  S+S P PP+           P +SS S     S S +S   S +P   
Sbjct: 354 P-SPHSLPPA--SSSAPAPPM---------RFPYSSSSSSSAAASSSSSSSSSSASPFPA 401

Query: 507 KELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSL-- 564
            +     P     P  L+        + N+  ++    L       +  P   P   L  
Sbjct: 402 SQALPSYPHSFPPPTSLS--------VSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLA 453

Query: 565 ------DPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSS-----KTESVSDKEDKPPLA 613
                  PFPP                  T+ P   PVS+     + +    ++ +    
Sbjct: 454 NSNAHPGPFPP------------STGAQSTAHP---PVSTHHHHHQQQQQQQQQQQQQQQ 498

Query: 614 PSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLL 673
                 G   PPPP     G+ P  L  G      P A      +L P      P  P  
Sbjct: 499 QQQQHHGNSGPPPP-----GAFPHPLEGGSSHHAHPYAMSPSLGSLRP-----YPPGP-- 546

Query: 674 SVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP- 732
                   P S    + + P+ P +++  +   S    SY P  H  P+ Q PQ  PYP 
Sbjct: 547 ---AHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSY-PCSHPSPS-QGPQGAPYPF 601

Query: 733 ------------VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAG----- 775
                       +S  +        G K + PP      + A +P   + A   G     
Sbjct: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS 661

Query: 776 -PPLVAATP---YSSYIPYNPQQF-PGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSH 830
            P     TP     +  P  P  F PG P  + P    P+ P   P L   P    SG  
Sbjct: 662 PPSFRTGTPPGYRGTSPPAGPGTFKPGSPT-VGPGPLPPAGPSGLPSLPPPPAAPASGPP 720

Query: 831 PQAIVSSSTP--QYPSAEQPTPQA 852
             A      P  +Y + E P P A
Sbjct: 721 LSATQIKQEPAEEYETPESPVPPA 744



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 133/590 (22%), Positives = 201/590 (34%), Gaps = 102/590 (17%)

Query: 351  PLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSP 410
            P P   R    G  + ++  G +PG        P      +P PG        GP    P
Sbjct: 636  PPPYGKRAPSPGAYKTATPPGYKPG-------SPPSFRTGTP-PGYRGTSPPAGPGTFKP 687

Query: 411  KAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKS------------AAPAPI 458
             +  P  G   L  P   PSG  S+PPPPA     PP S                +P P 
Sbjct: 688  GS--PTVGPGPL--PPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPP 743

Query: 459  SASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRT- 517
            + S   PP    VP+ ++     +   D G  S   A   +   P +  +L+ K      
Sbjct: 744  ARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSC--ARSDLYFVPLEGSKLAKKRADLVE 801

Query: 518  ---LEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKL-QPSSSPEN--SLDPFPPRI 571
                E ++ AR   +    +  +K  + E+ R+     KL Q   +P    SL P P R 
Sbjct: 802  KVRREAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRP 861

Query: 572  LKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPC--P 629
              E           + T  P   P +    ++S+   +P +   G    P   P     P
Sbjct: 862  PFEPG-------SAVATVPPYLGPDTPALRTLSEYA-RPHVMSPGNRNHPFYVPLGAVDP 913

Query: 630  SQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTS--PGP 687
               G     L   +     P A + ++     + ++    KP   V  S   P    PGP
Sbjct: 914  GLLGYNVPALYSSD-----PAAREREREARERDLRD--RLKPGFEVKPSELEPLHGVPGP 966

Query: 688  RTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQ--APQMYPYPVSNSV-PGQQGKY 744
                 P                        H G A+Q   P ++P+P   S+ P ++ + 
Sbjct: 967  GLDPFPR-----------------------HGGLALQPGPPGLHPFPFHPSLGPLERERL 1003

Query: 745  RGAKG-SLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQ--QFPGQPAM 801
              A G +L P  S   + A+     +  AA G   +A     +  P++ Q         +
Sbjct: 1004 ALAAGPALRPDMSYAERLAAERQHAERVAALGNDPLARLQMLNVTPHHHQHSHIHSHLHL 1063

Query: 802  MQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSY 861
             Q  A + +     P++      L SGSH   I       YP+   P P          +
Sbjct: 1064 HQQDAIHAASASVHPLIDP----LASGSHLTRI------PYPAGTLPNPLL-------PH 1106

Query: 862  PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQ 911
            P H  ++  HQ   A  P    P S  +AP    HQ  QA H  S + Q+
Sbjct: 1107 PLHENEVLRHQLFAA--PYRDLPASL-SAPMSAAHQL-QAMHAQSAELQR 1152



 Score = 40.4 bits (93), Expect = 0.009
 Identities = 68/298 (22%), Positives = 92/298 (30%), Gaps = 41/298 (13%)

Query: 385 HHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRM 444
           HH ++  P PG+    + GG S  +     P   + +L S    P G   +PPP      
Sbjct: 503 HHGNSGPPPPGAFPHPLEGGSSHHA----HPYAMSPSLGSLRPYPPGPAHLPPP------ 552

Query: 445 YPPRSPKSAAP--APISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLA 502
           +   S   A P   P+S+S       S+  TS  S P +      G        P +   
Sbjct: 553 HSQVSYSQAGPNGPPVSSSS-----NSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTV 607

Query: 503 PTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPEN 562
            T    LST     T+            PG     KR       K       +P S    
Sbjct: 608 TTSSATLSTVIA--TVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS---- 661

Query: 563 SLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPE 622
                PP      P G         TS P G                PP  PSG    P 
Sbjct: 662 -----PPSFRTGTPPGYRG------TSPPAGPGTFKPGSPTVGPGPLPPAGPSGL---PS 707

Query: 623 QPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTS 680
            PPPP    +G P    +      + P  E     +  P A+  +P   ++ V    S
Sbjct: 708 LPPPPAAPASGPP----LSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHAS 761



 Score = 37.0 bits (84), Expect = 0.099
 Identities = 31/95 (32%), Positives = 37/95 (38%), Gaps = 18/95 (18%)

Query: 12  QPQQPPPTQQAVARRPPG--GTSPPNGGL----------PGPL---ATSAAPPGPPAAAS 56
           +P  PP  +      PPG  GTSPP G            PGPL     S  P  PP  A+
Sbjct: 658 KPGSPPSFRTGT---PPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAA 714

Query: 57  PCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERP 91
           P  GP  +A    +  AE    P+ P P      P
Sbjct: 715 PASGPPLSATQIKQEPAEEYETPESPVPPARSPSP 749



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 22/52 (42%), Positives = 25/52 (48%), Gaps = 6/52 (11%)

Query: 4   PQPLQQ--PSQPQQ-PPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPP 52
           P P  Q  PS P   PPPT  +V+ +PP  T P    LP     S  PP PP
Sbjct: 398 PFPASQALPSYPHSFPPPTSLSVSNQPPKYTQP---SLPSQAVWSQGPPPPP 446



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 32/104 (30%), Positives = 37/104 (35%), Gaps = 19/104 (18%)

Query: 8   QQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGS 67
           QQ  Q QQ    QQ   +       PP G  P PL   ++    P A SP LG       
Sbjct: 485 QQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGS------ 538

Query: 68  GLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPPQS 111
                    L P PP P  H   P +    S  G +   GPP S
Sbjct: 539 ---------LRPYPPGP-AHLPPPHSQVSYSQAGPN---GPPVS 569



 Score = 33.9 bits (76), Expect = 0.84
 Identities = 34/113 (30%), Positives = 42/113 (37%), Gaps = 16/113 (14%)

Query: 4   PQPLQQPS-QPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPV 62
           P PL  PS QP    P Q   +  P    +P     P    TS     PP A  P   P 
Sbjct: 161 PPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPP--HPQ 218

Query: 63  AAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK--GPPQSPV 113
              G     G  G+L+  P  P+      G  A  S  G + GK   PP +P+
Sbjct: 219 LYPG-----GTGGVLSGPPMGPK------GGGAASSVGGPNGGKQHPPPTTPI 260



 Score = 33.1 bits (74), Expect = 1.4
 Identities = 28/96 (29%), Positives = 31/96 (32%), Gaps = 3/96 (3%)

Query: 14  QQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGA 73
           Q PPPT            +PP      P+     P  PP A  P + P       LR   
Sbjct: 252 QHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLN 311

Query: 74  EGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGPP 109
               A   PP    Q  PG      A GQ  G  PP
Sbjct: 312 N---ASASPPGLGAQPLPGHLPSPHAMGQGMGGLPP 344


>gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
            sapiens]
          Length = 1858

 Score = 74.3 bits (181), Expect = 6e-13
 Identities = 114/445 (25%), Positives = 154/445 (34%), Gaps = 67/445 (15%)

Query: 651  AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQY 710
            +EQ+ +   +   K   P  P L     +STP +P    + +P  P    G    Y P +
Sbjct: 1425 SEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSP--YRPHH 1482

Query: 711  ISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQA 770
             S  PQ+  G   + PQ   YP + ++P      +   G+L  Q       A+     Q 
Sbjct: 1483 -SQSPQV--GTPQREPQRNFYPAAQNLPANT--QQATSGTLFTQTPSGQSSATYSQFNQQ 1537

Query: 771  A--AAAGPPLVAATPYSSYIP----------YNP----------------QQFPGQPAMM 802
            +  + A PP     P SSY            YN                 Q  PG  +  
Sbjct: 1538 SLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQ 1597

Query: 803  QPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYP 862
                H+ +   F P    NP +     H Q   +   P  P    P P  +      S+ 
Sbjct: 1598 TVPGHHVTPGHFLP--SQNPTI-----HHQTAAAVVPPPPPPPPAPGPHLVQQP--NSHQ 1648

Query: 863  HHATQLHAHQPQPATTPTGSQPQSQHAA---------PSPVQHQAGQAPHLGSGQPQQNL 913
             H+   H   P  A TP GS   SQ A          P P  H     PH  +G      
Sbjct: 1649 QHSVA-HVVGPVHAVTP-GSHIHSQTAGHHLPPPPPPPGPAPHHH-PPPHPSTGLQGLQA 1705

Query: 914  YHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHH--QQLPHGFTNMAHVTQAHVQTG 971
             H   +   PP  PP P   S  +S     +  A+HH   Q P  F + AH T     + 
Sbjct: 1706 QHQHVVNSAPPP-PPPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQ 1764

Query: 972  ITAAPPPHPGAPHPPQVMLLHPPQSHGGP---PQGAVPQSGVPALSASTPSPYP-YIGHP 1027
             T      PG  H P     H P    GP   PQG    + +P  +AS   P+P  +  P
Sbjct: 1765 ATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQG---PNSIPTPTASGFCPHPGSVALP 1821

Query: 1028 QGEQ-PGQAPGFPGGADDRIPPLPP 1051
             G Q P QA   PG        +PP
Sbjct: 1822 HGVQGPQQASPVPGQIPIHRAQVPP 1846



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 136/590 (23%), Positives = 205/590 (34%), Gaps = 109/590 (18%)

Query: 421  TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASC---PEPPIGSAVPTSSAS 477
            T   PS   S  T   PP    +M  P SP S  PA         P+P   S V  S A 
Sbjct: 1335 TNECPSPDTSQNTCKSPP----KMSKPGSPGSVIPAQAHGKIFTKPDPQWDSTVSASEAE 1390

Query: 478  --IPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQN 535
              + + + +    + + + A  K     T V+  S+++  + L            P L+N
Sbjct: 1391 NGVHLKTELQQKQLSNNNQALSKNHPPQTHVRN-SSEQLSQKLPSVPTKLHCPPSPHLEN 1449

Query: 536  EQKRFQLEE------------LRKFGAQFKLQPSSSPENSLDPFPPR-----ILKEEPKG 578
              K                   ++ G+ ++   S SP+       P+       +  P  
Sbjct: 1450 PPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPAN 1509

Query: 579  KEKEVDG-LLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQT---GS 634
             ++   G L T  P G   SS T S  +++       S  +  P  PPPP PS +     
Sbjct: 1510 TQQATSGTLFTQTPSGQ--SSATYSQFNQQ-------SLNSTAPPPPPPPPPSSSYYQNQ 1560

Query: 635  PPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPS 694
             P    +  ++ +G +++Q    T  PN           ++  +TS  T PG   H TP 
Sbjct: 1561 QPSANFQNYNQLKGSLSQQT-VFTSGPNQ----------ALPGTTSQQTVPG--HHVTPG 1607

Query: 695  IPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVS---NSVPGQQGKYRGAK--G 749
               L +    ++     + +P     P    P +   P S   +SV    G         
Sbjct: 1608 -HFLPSQNPTIHHQTAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGS 1666

Query: 750  SLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYP 809
             +  Q +  H P   PP        GP      P+    P+      G  A  Q + +  
Sbjct: 1667 HIHSQTAGHHLPPPPPP-------PGP-----APHHHPPPHPSTGLQGLQAQHQHVVNSA 1714

Query: 810  SQPVFAPMLQSNPRMLTSGSHPQAIVS------SSTPQYPSAEQPT--PQALYATVHQSY 861
              P   P   S   +L SG H  +  +         P +PS+  PT  P    AT H + 
Sbjct: 1715 PPPPPPPPPSS---VLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHHTTL 1771

Query: 862  ----PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPG 917
                 H  +    H P P T P   QPQ  ++ P+P    +G  PH GS           
Sbjct: 1772 GPGPQHQPSGTGPHCPLPVTGP-HLQPQGPNSIPTPT--ASGFCPHPGS----------- 1817

Query: 918  ALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAH 967
                   +LP G   Q PQ + P P  +  IH  Q+P  F N  H +  H
Sbjct: 1818 ------VALPHG--VQGPQQASPVPGQI-PIHRAQVPPTFQNNYHGSGWH 1858



 Score = 40.0 bits (92), Expect = 0.012
 Identities = 37/151 (24%), Positives = 54/151 (35%), Gaps = 17/151 (11%)

Query: 340  PSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEAR 399
            PS     G +    Q +   P  G     S    P +   P +  HH   ++ GPG + +
Sbjct: 1723 PSSVLASGHHTTSAQALHHPPHQGPPLFPS-SAHPTVPPYPSQATHH---TTLGPGPQHQ 1778

Query: 400  GINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPIS 459
                 PS   P    P+ G      P  +P G  S+P P A G  + P     A P  + 
Sbjct: 1779 -----PSGTGPHCPLPVTG------PHLQPQGPNSIPTPTASG--FCPHPGSVALPHGVQ 1825

Query: 460  ASCPEPPIGSAVPTSSASIPVTSSVSDPGVG 490
                  P+   +P   A +P T   +  G G
Sbjct: 1826 GPQQASPVPGQIPIHRAQVPPTFQNNYHGSG 1856


>gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
            sapiens]
          Length = 1858

 Score = 74.3 bits (181), Expect = 6e-13
 Identities = 114/445 (25%), Positives = 154/445 (34%), Gaps = 67/445 (15%)

Query: 651  AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQY 710
            +EQ+ +   +   K   P  P L     +STP +P    + +P  P    G    Y P +
Sbjct: 1425 SEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSP--YRPHH 1482

Query: 711  ISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQA 770
             S  PQ+  G   + PQ   YP + ++P      +   G+L  Q       A+     Q 
Sbjct: 1483 -SQSPQV--GTPQREPQRNFYPAAQNLPANT--QQATSGTLFTQTPSGQSSATYSQFNQQ 1537

Query: 771  A--AAAGPPLVAATPYSSYIP----------YNP----------------QQFPGQPAMM 802
            +  + A PP     P SSY            YN                 Q  PG  +  
Sbjct: 1538 SLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQ 1597

Query: 803  QPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYP 862
                H+ +   F P    NP +     H Q   +   P  P    P P  +      S+ 
Sbjct: 1598 TVPGHHVTPGHFLP--SQNPTI-----HHQTAAAVVPPPPPPPPAPGPHLVQQP--NSHQ 1648

Query: 863  HHATQLHAHQPQPATTPTGSQPQSQHAA---------PSPVQHQAGQAPHLGSGQPQQNL 913
             H+   H   P  A TP GS   SQ A          P P  H     PH  +G      
Sbjct: 1649 QHSVA-HVVGPVHAVTP-GSHIHSQTAGHHLPPPPPPPGPAPHHH-PPPHPSTGLQGLQA 1705

Query: 914  YHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHH--QQLPHGFTNMAHVTQAHVQTG 971
             H   +   PP  PP P   S  +S     +  A+HH   Q P  F + AH T     + 
Sbjct: 1706 QHQHVVNSAPPP-PPPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQ 1764

Query: 972  ITAAPPPHPGAPHPPQVMLLHPPQSHGGP---PQGAVPQSGVPALSASTPSPYP-YIGHP 1027
             T      PG  H P     H P    GP   PQG    + +P  +AS   P+P  +  P
Sbjct: 1765 ATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQG---PNSIPTPTASGFCPHPGSVALP 1821

Query: 1028 QGEQ-PGQAPGFPGGADDRIPPLPP 1051
             G Q P QA   PG        +PP
Sbjct: 1822 HGVQGPQQASPVPGQIPIHRAQVPP 1846



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 136/590 (23%), Positives = 205/590 (34%), Gaps = 109/590 (18%)

Query: 421  TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASC---PEPPIGSAVPTSSAS 477
            T   PS   S  T   PP    +M  P SP S  PA         P+P   S V  S A 
Sbjct: 1335 TNECPSPDTSQNTCKSPP----KMSKPGSPGSVIPAQAHGKIFTKPDPQWDSTVSASEAE 1390

Query: 478  --IPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQN 535
              + + + +    + + + A  K     T V+  S+++  + L            P L+N
Sbjct: 1391 NGVHLKTELQQKQLSNNNQALSKNHPPQTHVRN-SSEQLSQKLPSVPTKLHCPPSPHLEN 1449

Query: 536  EQKRFQLEE------------LRKFGAQFKLQPSSSPENSLDPFPPR-----ILKEEPKG 578
              K                   ++ G+ ++   S SP+       P+       +  P  
Sbjct: 1450 PPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPAN 1509

Query: 579  KEKEVDG-LLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQT---GS 634
             ++   G L T  P G   SS T S  +++       S  +  P  PPPP PS +     
Sbjct: 1510 TQQATSGTLFTQTPSGQ--SSATYSQFNQQ-------SLNSTAPPPPPPPPPSSSYYQNQ 1560

Query: 635  PPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPS 694
             P    +  ++ +G +++Q    T  PN           ++  +TS  T PG   H TP 
Sbjct: 1561 QPSANFQNYNQLKGSLSQQT-VFTSGPNQ----------ALPGTTSQQTVPG--HHVTPG 1607

Query: 695  IPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVS---NSVPGQQGKYRGAK--G 749
               L +    ++     + +P     P    P +   P S   +SV    G         
Sbjct: 1608 -HFLPSQNPTIHHQTAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGS 1666

Query: 750  SLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYP 809
             +  Q +  H P   PP        GP      P+    P+      G  A  Q + +  
Sbjct: 1667 HIHSQTAGHHLPPPPPP-------PGP-----APHHHPPPHPSTGLQGLQAQHQHVVNSA 1714

Query: 810  SQPVFAPMLQSNPRMLTSGSHPQAIVS------SSTPQYPSAEQPT--PQALYATVHQSY 861
              P   P   S   +L SG H  +  +         P +PS+  PT  P    AT H + 
Sbjct: 1715 PPPPPPPPPSS---VLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHHTTL 1771

Query: 862  ----PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPG 917
                 H  +    H P P T P   QPQ  ++ P+P    +G  PH GS           
Sbjct: 1772 GPGPQHQPSGTGPHCPLPVTGP-HLQPQGPNSIPTPT--ASGFCPHPGS----------- 1817

Query: 918  ALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAH 967
                   +LP G   Q PQ + P P  +  IH  Q+P  F N  H +  H
Sbjct: 1818 ------VALPHG--VQGPQQASPVPGQI-PIHRAQVPPTFQNNYHGSGWH 1858



 Score = 40.0 bits (92), Expect = 0.012
 Identities = 37/151 (24%), Positives = 54/151 (35%), Gaps = 17/151 (11%)

Query: 340  PSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEAR 399
            PS     G +    Q +   P  G     S    P +   P +  HH   ++ GPG + +
Sbjct: 1723 PSSVLASGHHTTSAQALHHPPHQGPPLFPS-SAHPTVPPYPSQATHH---TTLGPGPQHQ 1778

Query: 400  GINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPIS 459
                 PS   P    P+ G      P  +P G  S+P P A G  + P     A P  + 
Sbjct: 1779 -----PSGTGPHCPLPVTG------PHLQPQGPNSIPTPTASG--FCPHPGSVALPHGVQ 1825

Query: 460  ASCPEPPIGSAVPTSSASIPVTSSVSDPGVG 490
                  P+   +P   A +P T   +  G G
Sbjct: 1826 GPQQASPVPGQIPIHRAQVPPTFQNNYHGSG 1856


>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
          Length = 1336

 Score = 73.9 bits (180), Expect = 7e-13
 Identities = 89/370 (24%), Positives = 120/370 (32%), Gaps = 51/370 (13%)

Query: 720  GPAVQAPQMYPYP----------VSNSVPGQQGKYR--GAKGSLPPQRSDQHQPASAPP- 766
            GP  Q PQ +  P               PG QG++R  G +G + PQ    HQ    P  
Sbjct: 592  GPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQG 651

Query: 767  MMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLT 826
             M      GPP     P   + P   Q+ PG    + P      Q    P     P+   
Sbjct: 652  FMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQ--- 708

Query: 827  SGSHPQAIVSSSTPQYPSAE--------------QPTPQALYATVHQSYPHHATQLHAHQ 872
                PQ  +    P  P                  P P+ +    H             Q
Sbjct: 709  GPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQ 768

Query: 873  PQPATTPT-GSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNL---YHPGALTGTPPSLPP 928
               +  P  G  P+     P P ++Q      +  G P Q +   + PG L G  P    
Sbjct: 769  GPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMR 828

Query: 929  GPSA-QSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQ 987
            GP   +  Q   PQ + +      + P G  +     Q  +       PPP  G   PP 
Sbjct: 829  GPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSL------GPPPQGGMQGPPG 882

Query: 988  VMLLHPPQSHGGPPQGAVP--QSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPG----G 1041
                  P     P QG +P  Q   P L     +P+    + +G+  G  P  PG    G
Sbjct: 883  PQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPF----NQEGQSTGPPPLIPGLGQQG 938

Query: 1042 ADDRIPPLPP 1051
            A  RIPPL P
Sbjct: 939  AQGRIPPLNP 948



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 89/330 (26%), Positives = 104/330 (31%), Gaps = 45/330 (13%)

Query: 758  QHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAP- 816
            Q  P+S  P++      G   ++  P     P+  QQ P   A M P      Q  F P 
Sbjct: 573  QPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPG---PQGQFRPP 629

Query: 817  -----MLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAH 871
                 M    P +   G  PQ  +    PQ P    P PQ ++    Q    H       
Sbjct: 630  GPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGP--QGMQRHPGPHGPL 687

Query: 872  QPQPATTPTGSQPQSQHAAPS----PVQHQAGQAP-----HLGSGQPQ--QNLYHPGALT 920
             PQ    P GS     H  P     P  H   Q P     HLG   P   Q +  P    
Sbjct: 688  GPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPR 747

Query: 921  GT-----PPSLPPGPSAQSPQSSFPQ-PAAVYAIHHQQLPHGFTNMAHVTQAHVQTG-IT 973
            G      P  +  GP +Q  Q    Q P         Q P G        Q     G I 
Sbjct: 748  GMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPG----PRENQGPAPQGMIM 803

Query: 974  AAPPPHPGAPHPPQVMLLHPPQSHGGPP-----QGAVPQS---GVPALSASTPSPYPYIG 1025
              PP     PHPP  +L H PQ   GP      QG  PQ    G P      P      G
Sbjct: 804  GHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQG 863

Query: 1026 HPQGE----QPGQAPGFPGGADDRIPPLPP 1051
             PQG       G   G PG    + P   P
Sbjct: 864  PPQGSLGPPPQGGMQGPPGPQGQQNPARGP 893



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 79/342 (23%), Positives = 111/342 (32%), Gaps = 55/342 (16%)

Query: 350 IPLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMS 409
           +P PQ +  GP+G  R     G       L P+GP       PGP    +G +G    M 
Sbjct: 665 LPRPQDMH-GPQGMQRHPGPHG------PLGPQGP-------PGP----QGSSGPQGHMG 706

Query: 410 PKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAP------------ 457
           P+     +G      P   P G      PP    M  P  P+     P            
Sbjct: 707 PQGPPGPQGHIGPQGPPG-PQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQ 765

Query: 458 -ISASCPEPPIGSAVPTSSASIPVTSSVSDPGV-GSISPASPKISLAPTDVKELSTKEPG 515
            I     + P+    P      P       P   G I    P+    P     L    P 
Sbjct: 766 GIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQ 825

Query: 516 RTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEE 575
               PQE+  + G  P           +ELR  G          P+ SL P PP+   + 
Sbjct: 826 EMRGPQEIRGMQGPPP---QGSMLGPPQELR--GPPGSQSQQGPPQGSLGP-PPQGGMQG 879

Query: 576 PKGKEKEVDGLLTSEPMGSPV---SSKTESVSD-----------KEDKPPLAPSGGTEGP 621
           P G + + +      P   P+     KT  + D               PPL P  G +G 
Sbjct: 880 PPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGA 939

Query: 622 E-QPPPPCPSQTGSPPVGLIKGEDKDE-GPVAEQVKKSTLNP 661
           + + PP  P Q   P  G  +G      GP++E+  + +  P
Sbjct: 940 QGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGP 981



 Score = 39.7 bits (91), Expect = 0.015
 Identities = 57/199 (28%), Positives = 73/199 (36%), Gaps = 33/199 (16%)

Query: 612 LAPSG--GTEGPEQPPPPCPSQTGSPPVGLIKGEDKD--EGPVAEQVKKSTLNPNAKEFN 667
           L P G  GT+G + PP P   Q    P G+  G      +GPV+ Q     LNP   +  
Sbjct: 729 LGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVS-QGPLMGLNPRGMQ-G 786

Query: 668 PTKPLLSVNKSTSTPTSPG------PRTHSTPSIP--VLTAGQSGLYSPQYISYIPQIHM 719
           P  P     +    P   G      P+    P  P  +L  G   +  PQ I  +     
Sbjct: 787 PPGP-----RENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGM----Q 837

Query: 720 GPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSL--PPQRSDQHQPASAPPMMQAAAAAGPP 777
           GP  Q   + P       PG Q +    +GSL  PPQ   Q  P    P  Q   A GP 
Sbjct: 838 GPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPG---PQGQQNPARGP- 893

Query: 778 LVAATPYSSYIPYNPQQFP 796
                P    IP+  Q+ P
Sbjct: 894 ----HPSQGPIPFQQQKTP 908



 Score = 38.9 bits (89), Expect = 0.026
 Identities = 41/151 (27%), Positives = 51/151 (33%), Gaps = 44/151 (29%)

Query: 2   LKPQPLQQPSQPQQPP-----------PTQQAVARRPPGGT------------------- 31
           L P+ +Q P  P++             P Q+     PPGG                    
Sbjct: 779 LNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQG 838

Query: 32  SPPNGGLPGPLATSAAPPGPPAAASP---CLGPVAAAG-------SGLRRGAEGILAPQP 81
            PP G + GP      PPG  +   P    LGP    G        G +  A G    Q 
Sbjct: 839 PPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQG 898

Query: 82  PPPQQHQERP----GAAAIGSARGQSTGKGP 108
           P P Q Q+ P    G  A  +  GQSTG  P
Sbjct: 899 PIPFQQQKTPLLGDGPRAPFNQEGQSTGPPP 929



 Score = 38.5 bits (88), Expect = 0.034
 Identities = 48/195 (24%), Positives = 53/195 (27%), Gaps = 31/195 (15%)

Query: 859  QSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGA 918
            Q  P   T L   QP P   P    PQ     P P Q        +G   PQ     PG 
Sbjct: 573  QPPPSSGTPLLGPQPFPGQGPMSQIPQG-FQQPHPSQQMPMNMAQMGPPGPQGQFRPPGP 631

Query: 919  LTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPP 978
                 P  PP          F  P         Q P G                     P
Sbjct: 632  QGQMGPQGPPLHQGGGGPQGFMGP---------QGPQG---------------------P 661

Query: 979  HPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGF 1038
              G P P  +      Q H GP     PQ       +S P  +     P G Q    P  
Sbjct: 662  PQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQG 721

Query: 1039 PGGADDRIPPLPPPG 1053
            P G    + P  PPG
Sbjct: 722  PPGPQGHLGPQGPPG 736



 Score = 38.5 bits (88), Expect = 0.034
 Identities = 37/121 (30%), Positives = 41/121 (33%), Gaps = 21/121 (17%)

Query: 1   MLKPQPL-------QQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPA 53
           +L PQP        Q P   QQP P+QQ        G   P G           PPGP  
Sbjct: 582 LLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQG--------QFRPPGPQG 633

Query: 54  AASPCLGPVAAAGSGLRRGAEGILAPQPPP-----PQQHQERPGAAAIGSARGQSTGKGP 108
              P  GP    G G  +G  G   PQ PP     PQ      G        G    +GP
Sbjct: 634 QMGP-QGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGP 692

Query: 109 P 109
           P
Sbjct: 693 P 693



 Score = 38.1 bits (87), Expect = 0.044
 Identities = 39/128 (30%), Positives = 45/128 (35%), Gaps = 31/128 (24%)

Query: 4   PQPLQQPSQPQQPPPT---------QQAVARRP-PGGTSPPNGGLPGPLATSA-----AP 48
           PQ    P  PQ PP            Q + R P P G   P G  PGP  +S       P
Sbjct: 649 PQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGP-PGPQGSSGPQGHMGP 707

Query: 49  PGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGKGP 108
            GPP       GP    G     G +G L PQ PP  Q  + P         G    +GP
Sbjct: 708 QGPP-------GPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGP--------PGPRGMQGP 752

Query: 109 PQSPVFEG 116
           P     +G
Sbjct: 753 PHPHGIQG 760



 Score = 37.4 bits (85), Expect = 0.076
 Identities = 47/163 (28%), Positives = 55/163 (33%), Gaps = 21/163 (12%)

Query: 908  QPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQ------PAAVYAIHHQQL-PHGFTNM 960
            Q Q     P   +GTP   P     Q P S  PQ      P+    ++  Q+ P G    
Sbjct: 566  QKQVEQIQPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQ 625

Query: 961  AHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGV--PALSASTP 1018
                    Q G    PP H G   P   M    PQ   GPPQG      +  P      P
Sbjct: 626  FRPPGPQGQMG-PQGPPLHQGGGGPQGFM---GPQGPQGPPQGLPRPQDMHGPQGMQRHP 681

Query: 1019 SPYPYIG-----HPQGE---QPGQAPGFPGGADDRIPPLPPPG 1053
             P+  +G      PQG    Q    P  P G    I P  PPG
Sbjct: 682  GPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPG 724



 Score = 34.3 bits (77), Expect = 0.64
 Identities = 42/132 (31%), Positives = 49/132 (37%), Gaps = 30/132 (22%)

Query: 4   PQPLQQPSQPQ-----QPPPTQQAVA-----RRPPGGTSPPNGGLPGPLATSAAP----- 48
           PQ   +P  PQ     Q PP  Q          P G   PP G LP P            
Sbjct: 622 PQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQG-LPRPQDMHGPQGMQRH 680

Query: 49  PGPPAAASPCLGPVAAAGSGLRRGAEGILAPQ-PPPPQQH---QERPGAAAIGSARGQST 104
           PGP     P  GP    GS    G +G + PQ PP PQ H   Q  PG       +G   
Sbjct: 681 PGPHGPLGP-QGPPGPQGSS---GPQGHMGPQGPPGPQGHIGPQGPPG------PQGHLG 730

Query: 105 GKGPPQSPVFEG 116
            +GPP +   +G
Sbjct: 731 PQGPPGTQGMQG 742


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 112/392 (28%), Positives = 139/392 (35%), Gaps = 68/392 (17%)

Query: 683  TSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQG 742
            T PGP   S P  P   +G + L  P+     P  H  P    P +YP P      G   
Sbjct: 780  TGPGPHYLSGPLPPGTYSGPTQLIQPR----APGPHAMPVAPGPALYPAPAYTPELG--- 832

Query: 743  KYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGP-PLVAATPYSSYIPYNPQQFPG-QPA 800
                    L P+ S QH   S+P +       GP P VA  P +      P QF G + A
Sbjct: 833  --------LVPRSSPQHGVVSSPYV-----GVGPAPPVAGLPSAP-----PPQFSGPELA 874

Query: 801  MMQPMAHYPSQPVFAPM-LQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQ 859
            M    A      + AP+   + PR   + + P        PQ      PTP    A   Q
Sbjct: 875  MAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQ----PLPTPYTYPAGAKQ 930

Query: 860  SYP---HHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHP 916
              P   H ++ + A  P P   P   QPQ  H  P P Q    Q P         +L+ P
Sbjct: 931  PIPAQHHFSSGIPAGFPAPRIGP---QPQP-HPQPHPSQAFGPQPPQQPLPLQHPHLFPP 986

Query: 917  GALTGTPPSLPPGPSAQSPQSSFPQPAAVYA----IHHQQLPHGFTNMAHVTQAHVQTGI 972
             A    P  LPP    QSP    PQP  +      +H Q  P          Q  +    
Sbjct: 987  QA----PGLLPP----QSPYPYAPQPGVLGQPPPPLHTQLYPGP-------AQDPLPAHS 1031

Query: 973  TAAPPPHPGA---PHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQG 1029
             A P P PG    PHPP      P     GP    +   G  +   STPSP+        
Sbjct: 1032 GALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLV------ 1085

Query: 1030 EQPGQAPGFPGGADDRIPPLPPPGELKIVLAA 1061
              P  +PG PG    R P   PP  L+   AA
Sbjct: 1086 PSPAPSPG-PGPVPPRPPAAEPPPCLRRGAAA 1116



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 93/382 (24%), Positives = 119/382 (31%), Gaps = 74/382 (19%)

Query: 610  PPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNP- 668
            P   PS    GP     P P  T S P  LI  + +  GP A  V        A  + P 
Sbjct: 773  PSPFPSSTGPGPHYLSGPLPPGTYSGPTQLI--QPRAPGPHAMPVAPGPALYPAPAYTPE 830

Query: 669  ------TKPLLSVNKSTSTPTSPGPRTHSTPSIPV--------------LTAGQSGLYSP 708
                  + P   V  S      P P     PS P                T     + +P
Sbjct: 831  LGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAP 890

Query: 709  QYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMM 768
                  P+ +  PA   P  +P P    +P       GAK  +P Q    H  +S  P  
Sbjct: 891  IPSHTAPRPNPTPA-PPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQ----HHFSSGIPAG 945

Query: 769  QAAAAAGP---PLVAATPYSSYIPYNPQQ---------FPGQ-PAMMQPMAHYPSQPVFA 815
              A   GP   P     P  ++ P  PQQ         FP Q P ++ P + YP  P   
Sbjct: 946  FPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPG 1005

Query: 816  PMLQSNPRMLT--------------SGSHPQAIVSSSTPQYP--------SAEQPTPQAL 853
             + Q  P + T              SG+ P        P +P        S     PQA 
Sbjct: 1006 VLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAA 1065

Query: 854  YATVH------QSYPH-HATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGS 906
              T+       QS P  H     A  P P   P    P+   A P P   +   A  L S
Sbjct: 1066 PLTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVP----PRPPAAEPPPCLRRGAAAADLLS 1121

Query: 907  GQPQQNLYHPGALTGTPPSLPP 928
              P+       +  G  P L P
Sbjct: 1122 SSPESQHGGTQSPGGGQPLLQP 1143



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 113/459 (24%), Positives = 150/459 (32%), Gaps = 118/459 (25%)

Query: 374  PGLSSLPPRGPHHLDNSSP--------------GPGSEARGINGGPSRMSPKAQRPLRGA 419
            P  SS  P GPH+L    P               PG  A  +  GP+     A  P  G 
Sbjct: 775  PFPSSTGP-GPHYLSGPLPPGTYSGPTQLIQPRAPGPHAMPVAPGPALYPAPAYTPELGL 833

Query: 420  KTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE--PPIGSAVPTSSAS 477
               SSP +       V   P VG            PAP  A  P   PP  S    + A 
Sbjct: 834  VPRSSPQH------GVVSSPYVG----------VGPAPPVAGLPSAPPPQFSGPELAMAV 877

Query: 478  IPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQ 537
             P T++V        S  +P+ +  P          P + L          K P     Q
Sbjct: 878  RPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQP--IPAQ 935

Query: 538  KRFQLE-----ELRKFGAQFKLQPSSSPENSLDPFPPR--ILKEEPKGKEKEVDGLLTSE 590
              F           + G Q +  P   P  +  P PP+  +  + P     +  GLL   
Sbjct: 936  HHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLL--- 992

Query: 591  PMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPV 650
            P  SP               P AP  G  G  QPPPP  +Q       L  G  +D  P 
Sbjct: 993  PPQSPY--------------PYAPQPGVLG--QPPPPLHTQ-------LYPGPAQDPLPA 1029

Query: 651  AEQVKKSTLNPNAKEFNPTKPLLSVNKSTST-PTSP--GPRTHSTPSIPVLTAGQSGLYS 707
                      P+     P  P L+   + ST P  P   P T   PS    +AGQS    
Sbjct: 1030 HSGALPF---PSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPS----SAGQS---- 1078

Query: 708  PQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPM 767
                             +P + P P  +  P          G +PP+      PA+ PP 
Sbjct: 1079 ---------------TPSPHLVPSPAPSPGP----------GPVPPR-----PPAAEPPP 1108

Query: 768  MQAAAAAGPPLVAATPYSSYIPYNPQQFP--GQPAMMQP 804
                 AA   L++++P S    +   Q P  GQP ++QP
Sbjct: 1109 CLRRGAAAADLLSSSPESQ---HGGTQSPGGGQP-LLQP 1143



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 30/86 (34%), Positives = 37/86 (43%), Gaps = 18/86 (20%)

Query: 26   RPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPPPPQ 85
            RPPGG   P   LPGP    A PPG P A+ P   P+ ++          + +P P  PQ
Sbjct: 1508 RPPGGLESPVASLPGP----AEPPGLPPASLPESTPIPSS------SPPPLSSPLPEAPQ 1557

Query: 86   QHQERPGAAAIGSARGQSTGKGPPQS 111
              +E P   A  S        GPP S
Sbjct: 1558 PKEEPPVPEAPSS--------GPPSS 1575



 Score = 38.1 bits (87), Expect = 0.044
 Identities = 117/500 (23%), Positives = 163/500 (32%), Gaps = 91/500 (18%)

Query: 405  PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464
            P   +PK   P R         + P    S+PP    G    PR              P+
Sbjct: 718  PRPTAPKPLLPRREESEAVEAGDPPEELRSLPPDMVAG----PR-------------LPD 760

Query: 465  PPIGSAVPTSSASIPVTSSVSDPGVGSIS-PASPKISLAPTDVKELSTKEPGRTLEPQEL 523
              +GSA P      P  SS + PG   +S P  P     PT +  +  + PG    P   
Sbjct: 761  TFLGSATPLHFPPSPFPSS-TGPGPHYLSGPLPPGTYSGPTQL--IQPRAPGPHAMP--- 814

Query: 524  ARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEV 583
                   PG         L     +  +  L P SSP++ +   P         G    V
Sbjct: 815  -----VAPGP-------ALYPAPAYTPELGLVPRSSPQHGVVSSP-----YVGVGPAPPV 857

Query: 584  DGLLTSEP-------MGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPC----PSQT 632
             GL ++ P       +   V   T +V   +   P   +        PPPPC    P Q 
Sbjct: 858  AGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQP 917

Query: 633  GSPPVGLIKGEDKDEGPVAEQVKKSTLNP---NAKEFNP-----TKPLLSVNKSTSTPTS 684
               P     G  +   P+  Q   S+  P    A    P      +P  S       P  
Sbjct: 918  LPTPYTYPAGAKQ---PIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQ 974

Query: 685  PGPRTHSTPSIPVLTAGQS-GLYSPQY-ISYIPQ---IHMGPAVQAPQMYPYPVSNSVPG 739
            P P  H     P L   Q+ GL  PQ    Y PQ   +   P     Q+YP P  + +P 
Sbjct: 975  PLPLQH-----PHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPA 1029

Query: 740  QQG--KYRGAKGSLPPQRSDQHQPA-SAPPMMQAAA---AAGPPLVAATPYSSYIPYNPQ 793
              G   +       PP     + PA S  PM   AA     GP     +  S ++  +P 
Sbjct: 1030 HSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPA 1089

Query: 794  QFPG------QPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHP----QAIVSSSTPQYP 843
              PG      +P   +P          A +L S+P     G+      Q ++  +  +  
Sbjct: 1090 PSPGPGPVPPRPPAAEPPPCLRRGAAAADLLSSSPESQHGGTQSPGGGQPLLQPT--KVD 1147

Query: 844  SAEQPTPQALYATVHQSYPH 863
            +AE   PQAL       Y H
Sbjct: 1148 AAEGRRPQALRLIERDPYEH 1167



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 38/132 (28%), Positives = 43/132 (32%), Gaps = 28/132 (21%)

Query: 4    PQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGG-----LPGPLATSAAPPGPPAAASPC 58
            P P   P+  +QP P Q   +   P G   P  G      P P  + A  P PP    P 
Sbjct: 919  PTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPL 978

Query: 59   LGPVAAAGSGLRRGAEGILAP--------------QPPPPQQHQERPGAA----AIGSAR 100
              P           A G+L P              QPPPP   Q  PG A       S  
Sbjct: 979  QHPHLFPPQ-----APGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGA 1033

Query: 101  GQSTGKGPPQSP 112
                  GPPQ P
Sbjct: 1034 LPFPSPGPPQPP 1045



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 38/121 (31%), Positives = 44/121 (36%), Gaps = 19/121 (15%)

Query: 3    KPQPLQQPSQ------PQQPPPTQ-------QAVARRPPGGTSP-PNGGLPGPLATSAAP 48
            +P P   PSQ      PQQP P Q       QA    PP   SP P    PG L     P
Sbjct: 956  QPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPP--QSPYPYAPQPGVLGQPPPP 1013

Query: 49   PGPPAAASPCLGPVAAAGSGLRRGAEGILAPQPP-PPQQHQERPGAAAIGSARGQSTGKG 107
                    P   P+ A    L   + G   PQPP PP  +   P    +G      T +G
Sbjct: 1014 LHTQLYPGPAQDPLPAHSGALPFPSPG--PPQPPHPPLAYGPAPSTRPMGPQAAPLTIRG 1071

Query: 108  P 108
            P
Sbjct: 1072 P 1072



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 51/201 (25%), Positives = 73/201 (36%), Gaps = 29/201 (14%)

Query: 351  PLPQRVREGPRGGVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSP 410
            PL  ++  GP      + S G  P  S  PP+ PH      P P +   G    P  +  
Sbjct: 1013 PLHTQLYPGPAQDPLPAHS-GALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTI-- 1069

Query: 411  KAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSA 470
              + P    ++  SP   PS   S  P P      PPR P +           EPP    
Sbjct: 1070 --RGPSSAGQSTPSPHLVPSPAPSPGPGPV-----PPRPPAA-----------EPPPCLR 1111

Query: 471  VPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKV 530
               ++A +  +S  S  G G+ SP   +  L PT V     + P       +  R+  + 
Sbjct: 1112 RGAAAADLLSSSPESQHG-GTQSPGGGQPLLQPTKVDAAEGRRP-------QALRLIERD 1163

Query: 531  PGLQNEQKRFQLEELRKFGAQ 551
            P    E+ R   +EL  F  Q
Sbjct: 1164 PYEHPERLRQLQQELEAFRGQ 1184



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 28/94 (29%), Positives = 30/94 (31%), Gaps = 10/94 (10%)

Query: 4    PQPLQQPSQPQQPPPTQ-QAVARRPPG---------GTSPPNGGLPGPLATSAAPPGPPA 53
            P P   P QP  PP     A + RP G         G S      P P    +  P P  
Sbjct: 1035 PFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLVPSPAPSPGP 1094

Query: 54   AASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQH 87
               P   P A     LRRGA         P  QH
Sbjct: 1095 GPVPPRPPAAEPPPCLRRGAAAADLLSSSPESQH 1128



 Score = 32.0 bits (71), Expect = 3.2
 Identities = 37/148 (25%), Positives = 57/148 (38%), Gaps = 21/148 (14%)

Query: 421  TLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAP--APISASCPEPPIGSAVPTSSASI 478
            T++  S RP G    P     G   PP  P ++ P   PI +S P PP+ S +P +    
Sbjct: 1501 TIAKLSIRPPGGLESPVASLPGPAEPPGLPPASLPESTPIPSSSP-PPLSSPLPEAPQ-- 1557

Query: 479  PVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQK 538
                              P +  AP+     S+ E   +L P+  + +   + G Q   K
Sbjct: 1558 --------------PKEEPPVPEAPSSGPPSSSLELLASLTPEAFS-LDSSLRGKQRMSK 1602

Query: 539  RFQLEELRKFGAQFKLQPSSSPENSLDP 566
               L+     G +   +PS  P + LDP
Sbjct: 1603 HNFLQAHNGQGLR-ATRPSDDPLSLLDP 1629



 Score = 32.0 bits (71), Expect = 3.2
 Identities = 30/110 (27%), Positives = 42/110 (38%), Gaps = 25/110 (22%)

Query: 927  PPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPP 986
            PPG   +SP +S P PA    +    LP               T I ++ PP   +P P 
Sbjct: 1509 PPG-GLESPVASLPGPAEPPGLPPASLPES-------------TPIPSSSPPPLSSPLP- 1553

Query: 987  QVMLLHPPQSHGGPPQGAVPQSGVPA-----LSASTPSPYPYIGHPQGEQ 1031
                   PQ    PP    P SG P+     L++ TP  +      +G+Q
Sbjct: 1554 -----EAPQPKEEPPVPEAPSSGPPSSSLELLASLTPEAFSLDSSLRGKQ 1598



 Score = 31.2 bits (69), Expect = 5.4
 Identities = 26/84 (30%), Positives = 34/84 (40%), Gaps = 4/84 (4%)

Query: 560  PENSLDPFPPRILKEEPKGKEKEVDGLL-TSEPMGSPVSSKTESVSDKEDKPPLAPSGGT 618
            P +S+     ++    P G E  V  L   +EP G P +S  ES       PP   S   
Sbjct: 1494 PISSIQATIAKLSIRPPGGLESPVASLPGPAEPPGLPPASLPESTPIPSSSPPPLSSPLP 1553

Query: 619  EGP---EQPPPPCPSQTGSPPVGL 639
            E P   E+PP P    +G P   L
Sbjct: 1554 EAPQPKEEPPVPEAPSSGPPSSSL 1577



 Score = 30.8 bits (68), Expect = 7.1
 Identities = 30/111 (27%), Positives = 36/111 (32%), Gaps = 5/111 (4%)

Query: 7   LQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAG 66
           +Q P      P      A  PP    PP   LP P    A    P  A       + A  
Sbjct: 887 IQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGF 946

Query: 67  SGLRRGAEGILAPQPPPPQQHQERPGAAAIGSAR-----GQSTGKGPPQSP 112
              R G +    PQP P Q    +P    +          Q+ G  PPQSP
Sbjct: 947 PAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSP 997


>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
          Length = 2217

 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 113/438 (25%), Positives = 150/438 (34%), Gaps = 55/438 (12%)

Query: 621  PEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTS 680
            P  PPP  P  TG        G+    G     + + T  P      P  PL  V     
Sbjct: 708  PVLPPPSTPMPTGP-------GQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPV----- 755

Query: 681  TPTSPGPRTHSTPSIPVLTAGQSGLYSPQYIS--YIPQIHMGPAVQAP-QMYPYPVSNSV 737
                        P +P   A  S + +P  +    +PQ  + P  Q P QM P PV   +
Sbjct: 756  -----------PPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPI 804

Query: 738  PGQQGKYRGAKGSLPPQRSDQHQ---PASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQ 794
                G        LPP   D      P   PP   + A   P L A  P +S  P  P Q
Sbjct: 805  TPLAGI-----DGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPAS--PALPLQ 857

Query: 795  F------PGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVS-SSTPQYPSAEQ 847
                   PG P  M      P+ P   P+L   P  + + S   A+      P YP+A  
Sbjct: 858  AVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAA-- 915

Query: 848  PTPQALYATVHQSYPHHATQ-LHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGS 906
              PQ     V  S PHH  Q + A  PQPA  P  + P      P P        P   +
Sbjct: 916  -FPQMAPTDVPPS-PHHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPT 973

Query: 907  GQPQQNLYHPGALTGTPPSLPPGPS----AQSPQSSFPQPAAVYAIHHQQLPHGFTNMAH 962
             +P Q +  P  +    P LPP P+     +  Q   P+ AA  A    Q+  G     +
Sbjct: 974  -RPPQPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHP-APY 1031

Query: 963  VTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQG-AVPQSGVPALSASTPSPY 1021
                  Q      PP    +P  P+V+L   P+     P   A   + V ++   T +  
Sbjct: 1032 AVDVAAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLL 1091

Query: 1022 PYIGHPQGEQPGQAPGFP 1039
            P    P    PG A   P
Sbjct: 1092 PPANPPLPGGPGIASPCP 1109



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 66/233 (28%), Positives = 81/233 (34%), Gaps = 44/233 (18%)

Query: 840  PQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQH--------AAP 891
            P+ P A+Q     L  T+  S    A+       Q +T  + SQ   Q         AAP
Sbjct: 589  PEEPEADQ---HLLPPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAP 645

Query: 892  SPVQ----HQAGQAPHLGSGQPQQNLYH-PGALTGTPPSLPPGPSAQ-SPQSSFPQPAAV 945
            SP Q        + P L    P    Y  P A  G P    P P+   S Q  FP PA  
Sbjct: 646  SPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMS 705

Query: 946  YAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGP----- 1000
            +A     LP   T M                P  PG P PP      PP +   P     
Sbjct: 706  FA---PVLPPPSTPM----------------PTGPGQPAPPGQQ--PPPLAQPTPLPQVL 744

Query: 1001 -PQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRIPPLPPP 1052
             PQ  VP   VP       +P   +G P   +P Q P  P     ++PP  PP
Sbjct: 745  APQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPP 797



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 86/311 (27%), Positives = 103/311 (33%), Gaps = 53/311 (17%)

Query: 770  AAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRML---- 825
            A AA  P     +P  S  P  PQ  P   A  QP A  P  PV +    + P  L    
Sbjct: 641  ADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTA-APGLPVGSVPAPACPPSLQQHF 699

Query: 826  --TSGSHPQAIVSSSTPQ-------YPSAEQPTPQALYATVHQSY-PHHATQLHAHQPQP 875
               + S    +   STP         P  +QP P A    + Q   P     L   QP P
Sbjct: 700  PDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPL---QPVP 756

Query: 876  ATTPTGSQPQSQHAAPS---PVQHQAGQAPHLGSGQPQQ-------NLYHPGALTGTPPS 925
               P    P SQ  AP+   P+Q        L    PQ         +     + G PP+
Sbjct: 757  PHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPA 816

Query: 926  LPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHP 985
            LP  P+A  P    P P   Y      LP           A +     A P      PHP
Sbjct: 817  LPDLPTATVP----PVPPPQYFSPAVILPS--------LAAPLPPASPALPLQAVKLPHP 864

Query: 986  PQVMLLHP-----PQSHGGPPQGAVPQSGVPALSA-STPSPYPYIGHPQGEQPGQAPGFP 1039
            P   L  P     P +    P  AV   GV ALS  S  +  P        QP     FP
Sbjct: 865  PGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLP-------GQPVYPAAFP 917

Query: 1040 GGADDRIPPLP 1050
              A   +PP P
Sbjct: 918  QMAPTDVPPSP 928



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 53/179 (29%), Positives = 70/179 (39%), Gaps = 21/179 (11%)

Query: 352 LPQRVREGPRG----GVRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSR 407
           +P  + E  RG    G+    ++  RPG      R     D   P PG EA    G P  
Sbjct: 10  VPGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEP-PGLEAAEAPG-PQP 67

Query: 408 MSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA-VGRMYPPRSPKSAAPAPISASCPEP- 465
             P  +R L   KT    + R  G  + P P A V +   P +P  A P P+    P P 
Sbjct: 68  PQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGPD 127

Query: 466 PIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTL--EPQE 522
           PI +AV T+ A          P  G    A+  +        E +  EPGRT   EP+E
Sbjct: 128 PIAAAVETAPA----------PDGGPREEAAATVRKEDEGAAE-AKPEPGRTRRDEPEE 175



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 93/362 (25%), Positives = 127/362 (35%), Gaps = 71/362 (19%)

Query: 736  SVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSY-IPYNPQQ 794
            S PG    +    G    + S Q Q A+AP   Q     G       P + +  P  P+ 
Sbjct: 1271 SDPGTSPPHLSTCGLGTGEESRQSQ-ANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPES 1329

Query: 795  FPGQP-AMMQPMAHYPSQPVFAPMLQSN--PRMLTSGSHPQAIVSSSTPQYPSAEQPTPQ 851
             P  P + + P A   S P +   L S   P  L S    Q ++S + P  P    P P 
Sbjct: 1330 SPPLPLSSLPPEASQDSAP-YKDQLSSKEQPSFLAS----QQLLSQAGPSNPPGAPPAPL 1384

Query: 852  ALYATVHQSYPHH-ATQLHAHQPQPAT----------TPTG-------SQPQSQ-HAAPS 892
            A  +    + P   A    +  P+PA+          TP G       SQP ++ H AP 
Sbjct: 1385 APSSPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPL 1444

Query: 893  PVQHQA-GQAPHLGSGQPQQNLYHPGALTGTPPSLP-PGPSAQSPQSSFPQPAAVYAIHH 950
             VQ    G AP   + +              PP  P P P + +PQ +  QPA +     
Sbjct: 1445 AVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPL----- 1499

Query: 951  QQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQ-GAVP--- 1006
              LP      A V    + T    +PP  P  P  P   L       G PP+ G V    
Sbjct: 1500 --LP------AAVGAVSLATSQLPSPPLGPTVPPQPPSAL--ESDGEGPPPRVGFVDSTI 1549

Query: 1007 ------------QSGVPALSASTPSPYPY------IGHPQGEQPGQAPGFPGGADDRIPP 1048
                        Q  VP  SAS  +P         +   +G+QP        G D  +PP
Sbjct: 1550 KSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSE---VCGGDLALPP 1606

Query: 1049 LP 1050
            +P
Sbjct: 1607 VP 1608



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 179/825 (21%), Positives = 273/825 (33%), Gaps = 171/825 (20%)

Query: 1    MLKPQPL--QQPSQPQQPPPTQQAVARRPPGGTSPPNG---GLPGPLATSAAP-----PG 50
            ML PQP+   QP+ P +P P Q  +  +     +P +    G P P A   A      P 
Sbjct: 985  MLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPV 1044

Query: 51   PPAA------------ASPCLGP--------VAAAGSGLRRGAEGILAPQPPPPQQHQER 90
            PPAA            A+P L P        V+A+   +      +L P  PP       
Sbjct: 1045 PPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPP------L 1098

Query: 91   PGAAAIGSA------------RGQSTGKGPPQSPVFEGVYNNSRMLHFLTAVVGSTCDVK 138
            PG   I S               Q++   PP  P     Y  S +       +  +C+  
Sbjct: 1099 PGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGGSDVTS--GKELSDSCE-- 1154

Query: 139  VKNGTTYEGIFKTLSSKFELAVDAVHRKASEPAGGPRRE-----DIVDTMV---FKPSDV 190
               G    G  +  +++         R   E A  PR       +  D MV    +  + 
Sbjct: 1155 ---GAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDKMVECQLETHNH 1211

Query: 191  MLVHFRNVDFNYATKDKFTDSAIAMNSKVNGEHKEKVLQRWEGGDSNSDDYDLESDMSNG 250
             +V F+  D +    D+     +  +  +  E +  + Q  +  D   D    ++D   G
Sbjct: 1212 KMVTFK-FDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDMLSEDTDADRG 1270

Query: 251  WDPNEMFKFNEENYGVKTTYDSSLSSYTVPLEKDNSEEFRQRELRAAQLAREI-----ES 305
             DP      +    G+ T  +S  S    P+ + N     +R      +A        ES
Sbjct: 1271 SDPGTSPP-HLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAPES 1329

Query: 306  SPQYRLRIAMENDDGRTEEEKHSAVQR-QGSGRESPS-LASREGKYIPLPQRVREGPRGG 363
            SP   L           E  + SA  + Q S +E PS LAS++      P      P   
Sbjct: 1330 SPPLPLSSLPP------EASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAP 1383

Query: 364  VRCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGP------------------ 405
            +  SS     P +++LP  G     ++ P P S      GGP                  
Sbjct: 1384 LAPSS-----PPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAE 1438

Query: 406  SRMSPKAQRPLRG--AKTLSSPSNRPSGETSVP----PPPAVGRMYPPRSPKSAAPAPI- 458
            +  +P A +PL    A    +P    + + S P    PPPA     P  SP S  P P  
Sbjct: 1439 THEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPA-----PEPSPHSGTPQPAL 1493

Query: 459  -----------------SASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISL 501
                             ++  P PP+G  VP    S   +     P         P++  
Sbjct: 1494 GQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPP---------PRVGF 1544

Query: 502  APTDVKELSTKEPGRTLEPQELARIAGKVPGLQNE--QKRFQLEELRKFGAQFKLQPSSS 559
              + +K L  K   RTL  QE    +    G   E   + F LE LR  G Q + +    
Sbjct: 1545 VDSTIKSLDEKL--RTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLR--GDQPRSEVCGG 1600

Query: 560  PENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTE 619
             + +L P P   +    +  +  V+    +   G+ +   T S    E  P        +
Sbjct: 1601 -DLALPPVPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRD 1659

Query: 620  GPE--QPPPPCPSQTGSPPV----GLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLL 673
            G +        PS     P       ++  D+D G   E    S+  P      P   + 
Sbjct: 1660 GRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGE----SSAEP------PPSDMG 1709

Query: 674  SVNKSTSTPTSPGPRTHSTP---------SIPVLTAGQSGLYSPQ 709
            +V    S P + G R   +P         S P  T G+  + S Q
Sbjct: 1710 TVGGQASHPQTLGARALGSPRKRPEQQDVSSPAKTVGRFSVVSTQ 1754



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 49/199 (24%), Positives = 66/199 (33%), Gaps = 16/199 (8%)

Query: 874  QPATTPTGSQPQSQHAAPSPVQHQA---GQAPHLGSGQPQQNLYHPGALTGTPPSLPPGP 930
            QP        P      P P+Q Q     QA   G  +P++       L   PP+LP   
Sbjct: 551  QPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLL---PPTLPTSA 607

Query: 931  SAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVM- 989
            ++ +  S+F            Q       +  +  A          PP    P  PQ + 
Sbjct: 608  TSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQSLP 667

Query: 990  ---LLHPPQSHGGPPQGAVPQSGVP-ALSASTPSPY----PYIGHPQGEQPGQAPGFPGG 1041
                   P +  G P G+VP    P +L    P P     P +  P    P   PG P  
Sbjct: 668  SLGAYQQPTAAPGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMP-TGPGQPAP 726

Query: 1042 ADDRIPPLPPPGELKIVLA 1060
               + PPL  P  L  VLA
Sbjct: 727  PGQQPPPLAQPTPLPQVLA 745



 Score = 35.8 bits (81), Expect = 0.22
 Identities = 39/149 (26%), Positives = 60/149 (40%), Gaps = 16/149 (10%)

Query: 376 LSSLPPRGPHHLDNSSP-GPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRP-SGET 433
           L  +PP  P +L  +S  G  ++ + +    + + P AQ P +       P   P +G  
Sbjct: 752 LQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGID 811

Query: 434 SVPP-----PPAVGRMYPPRSPKSAAPAPI--SASCPEPPIGSAVPTSSASIPVTSSVSD 486
            +PP     P A     PP  P+  +PA I  S + P PP   A+P  +  +P       
Sbjct: 812 GLPPALPDLPTATVPPVPP--PQYFSPAVILPSLAAPLPPASPALPLQAVKLP-----HP 864

Query: 487 PGVGSISPASPKISLAPTDVKELSTKEPG 515
           PG     P    +  AP  +  L+   PG
Sbjct: 865 PGAPLAMPCRTIVPNAPATIPLLAVAPPG 893



 Score = 35.0 bits (79), Expect = 0.38
 Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 8/85 (9%)

Query: 12  QPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAA-----SPCLGPVAAAG 66
           +P  P P   A+  +P    +P + G P P+ T    P P AAA     +P  GP   A 
Sbjct: 92  RPAAPAPA--ALVAQPGAPGAPADAG-PEPVGTQEPGPDPIAAAVETAPAPDGGPREEAA 148

Query: 67  SGLRRGAEGILAPQPPPPQQHQERP 91
           + +R+  EG    +P P +  ++ P
Sbjct: 149 ATVRKEDEGAAEAKPEPGRTRRDEP 173



 Score = 35.0 bits (79), Expect = 0.38
 Identities = 38/150 (25%), Positives = 53/150 (35%), Gaps = 18/150 (12%)

Query: 910  QQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHGFTNMAHVTQ---- 965
            QQN+ H G        +   P+ ++P+SS P P +       Q    + +     +    
Sbjct: 1302 QQNVLHTGKRWFIICPVAEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSF 1361

Query: 966  -AHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYI 1024
             A  Q    A P   PGAP  P       P S   PP  A+PQ G    +++ P P    
Sbjct: 1362 LASQQLLSQAGPSNPPGAPPAPLA-----PSS---PPVTALPQDGAAPATSTMPEPASGT 1413

Query: 1025 GHPQGEQPGQAPGFPGGADDRIPPLPPPGE 1054
                G      PG P G    +    P  E
Sbjct: 1414 ASQAG-----GPGTPQGLTSELETSQPLAE 1438



 Score = 33.1 bits (74), Expect = 1.4
 Identities = 60/249 (24%), Positives = 90/249 (36%), Gaps = 50/249 (20%)

Query: 315  MENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGPRGG-VRCSSSRGGR 373
            ME     +   + S     G  R+   +AS       +PQ V    R   V  +   GG 
Sbjct: 1636 MEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGE 1695

Query: 374  PGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGET 433
             G SS  P            P S+   + G  S           GA+ L SP  RP  + 
Sbjct: 1696 AGESSAEP------------PPSDMGTVGGQASHPQTL------GARALGSPRKRPEQQD 1737

Query: 434  SVPPPPAVGR-----------MYPPRSPKSAAPAPI----SASCPEPPIGSAVPTSSASI 478
               P   VGR           +  P S + +AP  +    + S P+  +      +++SI
Sbjct: 1738 VSSPAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSI 1797

Query: 479  ------PVTSSVSDPGVGSISPASPKISL------APTDVKELST--KEPGR--TLEPQE 522
                  PV+S   D G  +  P   + SL      A   VK+ +   + P R  +L P+ 
Sbjct: 1798 EVGVGEPVSSDSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPET 1857

Query: 523  LARIAGKVP 531
             +R+  KVP
Sbjct: 1858 PSRVGMKVP 1866



 Score = 32.0 bits (71), Expect = 3.2
 Identities = 50/200 (25%), Positives = 71/200 (35%), Gaps = 31/200 (15%)

Query: 622  EQPPPPCPSQTGSPPVGLIKGE-DKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTS 680
            E P P  P  +   P+  +  E  +D  P  +Q+           F  ++ LLS    ++
Sbjct: 1320 EHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSK----EQPSFLASQQLLSQAGPSN 1375

Query: 681  TPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQA-----PQMYPYPVSN 735
             P +P P   +  S PV    Q G  +    S +P+   G A QA     PQ     +  
Sbjct: 1376 PPGAP-PAPLAPSSPPVTALPQDG--AAPATSTMPEPASGTASQAGGPGTPQGLTSELET 1432

Query: 736  SVP---------GQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSS 786
            S P           Q    G     P   +   + ASAP          PP    +P+S 
Sbjct: 1433 SQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAP-----REPLPPPAPEPSPHSG 1487

Query: 787  YIPYNPQQFPGQPAMMQPMA 806
                 PQ   GQPA + P A
Sbjct: 1488 ----TPQPALGQPAPLLPAA 1503



 Score = 31.6 bits (70), Expect = 4.2
 Identities = 20/56 (35%), Positives = 20/56 (35%)

Query: 2   LKPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASP 57
           L PQP   P     P PT       PP  T PP   LP        P  PP  A P
Sbjct: 944 LPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALP 999



 Score = 30.8 bits (68), Expect = 7.1
 Identities = 29/103 (28%), Positives = 41/103 (39%), Gaps = 10/103 (9%)

Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464
           P   SP    P   A    +    P     +P PP      P R+    APA I      
Sbjct: 831 PQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATI------ 884

Query: 465 PPIGSAVPTSSASIPVTSSVSD-PGVGSISPASPKISLAPTDV 506
            P+ +  P   A++ + S+V+  PG      A P+  +APTDV
Sbjct: 885 -PLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQ--MAPTDV 924



 Score = 30.4 bits (67), Expect = 9.2
 Identities = 23/74 (31%), Positives = 26/74 (35%), Gaps = 9/74 (12%)

Query: 13  PQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRG 72
           P  P  T Q +   PP    PP   LP        PP P     P L P         R 
Sbjct: 925 PPSPHHTVQNMRATPPQPALPPQPTLP---PQPVLPPQPTLPPQPVLPPQPT------RP 975

Query: 73  AEGILAPQPPPPQQ 86
            + +L PQP  P Q
Sbjct: 976 PQPVLPPQPMLPPQ 989



 Score = 30.4 bits (67), Expect = 9.2
 Identities = 27/76 (35%), Positives = 29/76 (38%), Gaps = 16/76 (21%)

Query: 10  PSQPQQPP-PTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLGPVAAAGSG 68
           P QP  PP PT       PP  T PP   LP P  T   PP P     P L P       
Sbjct: 939 PPQPALPPQPTLPPQPVLPPQPTLPPQPVLP-PQPT--RPPQPVLPPQPMLPP------- 988

Query: 69  LRRGAEGILAPQPPPP 84
                + +L PQP  P
Sbjct: 989 -----QPVLPPQPALP 999


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 167/711 (23%), Positives = 236/711 (33%), Gaps = 113/711 (15%)

Query: 305  SSPQYRLRIAMENDDGRTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGPRGGV 364
            SSPQ R R    + D  +  +    +   GS   S   +  + +       V   P+GG 
Sbjct: 400  SSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGG- 458

Query: 365  RCSSSRGGRPGLSSLPPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSS 424
               S RG   G S+           +S      + G   G S    K +RP    +   S
Sbjct: 459  ---SGRGSPSGGSTA---------EASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHS 506

Query: 425  PSNR----PSGETSVPPPPAVGRMYPPRSPK----SAAPAPISASCPEPPIGSAVPTSSA 476
               R    P G   +PP P   R   P+ P+      +    +A CP  P  S VP  S 
Sbjct: 507  LHQRGLAVPDGPLGLPPKPE--RKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLS- 563

Query: 477  SIPVTSSVSDPGVGSISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNE 536
                      PG     P SP+ +L+P+      +  P  TL P+ LA      PG    
Sbjct: 564  ----------PGGSRRPPRSPERTLSPSSGYSSQSGTP--TLPPKGLAGPPAS-PGKAQP 610

Query: 537  QKRFQLEELRKFGAQFKLQPSSSPENSLDPFP-----PRIL------------------- 572
             K  ++  LR  GA      +S   +S DP P     P+IL                   
Sbjct: 611  PKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPF 670

Query: 573  ---KEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKP-----PLAPSGGTEGPEQP 624
                 +P+        L     +  PVS+ T++       P     PL  S      + P
Sbjct: 671  SPPPSKPRSPNPAAPALAAPAVVPGPVST-TDASPQSPPTPQTTLTPLQESPVISKDQSP 729

Query: 625  PPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTL-NPNAKEFNPTKPLLSVNKSTSTPT 683
            PP  P     PP    K E   E P A +  +  L +PN   + P  P     +  S   
Sbjct: 730  PPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPN---WPPPPPPAPEEQDLSMAD 786

Query: 684  SPGPRTHSTPSIPVLTAGQSGLYSPQYIS---------YIPQIHMGPAVQAPQMYPYPV- 733
             P P            AG SG  SP+ +S            QI    +   P   P P  
Sbjct: 787  FPPPEEAFFSVASPEPAGPSG--SPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAP 844

Query: 734  SNSVPGQQGKYRG------AKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSY 787
            ++S PG   K         +KG  PP R D   P   P ++Q             P  + 
Sbjct: 845  ASSAPGHVAKLPQKEPVGCSKGGGPP-REDVGAPLVTPSLLQMVRLRSVGAPGGAPTPAL 903

Query: 788  IPYNPQQFPGQPAMMQPMAHYPSQPVFAPM--LQSNPRMLTSGSHPQAIVSSSTPQ-YPS 844
             P  PQ+ P + A+        + PV AP   L +  R+          +SS+ P   P 
Sbjct: 904  GPSAPQK-PLRRALSG-----RASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPE 957

Query: 845  AEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHL 904
            AE   PQ+  +T    +   + +L   +P    T    Q        S  + +  QAP  
Sbjct: 958  AEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKK 1017

Query: 905  GSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPH 955
                P      P    G PP   P         S+P+   + A     LPH
Sbjct: 1018 SPKAPPPVARKPS--VGVPPPASP---------SYPRAEPLTAPPTNGLPH 1057



 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 155/672 (23%), Positives = 212/672 (31%), Gaps = 137/672 (20%)

Query: 467  IGSAVPTSSASIPVTSSVSDPGV----GSISPASPKISLAPTDVKELSTKEPGRTLEPQE 522
            +G +  T +  +    S++ PG+    G   P SP +S++P     LS   P   L P  
Sbjct: 306  VGRSTGTRAPPLTRPMSLAVPGLTGGAGPAEPLSPAMSISP-QATYLSKLIPHAVLPPTV 364

Query: 523  LARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKE 582
                 G+               LR          S +   SL  F   +   +P+ +   
Sbjct: 365  DVVALGRC-------------SLRTLSRCSLHSASPASVRSLGRFSS-VSSPQPRSRHPS 410

Query: 583  VDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEG-PEQ--------PPPPCPSQTG 633
                 +S    S   S    VSD      L+  GG+EG PE         PPP   S  G
Sbjct: 411  -----SSSDTWSHSQSSDTIVSDGST---LSSKGGSEGQPESSTASNSVVPPPQGGSGRG 462

Query: 634  SPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTP 693
            SP            G  AE     ++  + +    +  L  + +    P  P  RTHS  
Sbjct: 463  SP----------SGGSTAEASDTLSIRSSGQLSGRSVSLRKLKR----PPPPPRRTHSLH 508

Query: 694  SIPVLTA-GQSGLYSPQYISYIPQIHMGPAVQ------APQMYPYPVSNSVPGQQGKYRG 746
               +    G  GL         PQ+   P         A    P P ++ VPG       
Sbjct: 509  QRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLS----- 563

Query: 747  AKGSLPPQRSDQ--------HQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQF--- 795
              GS  P RS +        +   S  P +     AGPP   A+P  +  P  P++    
Sbjct: 564  PGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPP---ASPGKAQPP-KPERVTSL 619

Query: 796  --PGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTS-------GSHPQAIVS-SSTPQYPSA 845
              PG        +   S    AP  +S P++LT          HP+     S  P  P +
Sbjct: 620  RSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRS 679

Query: 846  EQPTPQALYATV------------HQSYPHHATQLHAHQPQPATT----PTGSQPQSQHA 889
              P   AL A               QS P   T L   Q  P  +    P  S P S H 
Sbjct: 680  PNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHP 739

Query: 890  APSPVQHQ--AGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQS-PQSSFPQPAAVY 946
             P P +      +AP   S   ++ L  P      PP  PP P  Q    + FP P   +
Sbjct: 740  PPPPTKKPEVVVEAPS-ASETAEEPLQDPN----WPPPPPPAPEEQDLSMADFPPPEEAF 794

Query: 947  AIHHQQLPHG-----------FTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQ 995
                   P G             + +  T   +Q   +  PPP P AP P      H  +
Sbjct: 795  FSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAK 854

Query: 996  SHGGPPQGAVPQSGVPALSASTPSPYP---------YIGHPQG-EQPGQAPGFP-----G 1040
                 P G     G P      P   P          +G P G   P   P  P      
Sbjct: 855  LPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRR 914

Query: 1041 GADDRIPPLPPP 1052
                R  P+P P
Sbjct: 915  ALSGRASPVPAP 926



 Score = 38.9 bits (89), Expect = 0.026
 Identities = 32/116 (27%), Positives = 46/116 (39%), Gaps = 10/116 (8%)

Query: 5   QPLQQPSQPQQPPPTQQ----AVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAASPCLG 60
           +PLQ P+ P  PPP  +    ++A  PP   +  +   P P   S +   P   +SP   
Sbjct: 762 EPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGS---PELVSSPAAS 818

Query: 61  PVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSAR---GQSTGKGPPQSPV 113
             +A    ++        P PP P      PG  A    +   G S G GPP+  V
Sbjct: 819 SSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDV 874



 Score = 35.0 bits (79), Expect = 0.38
 Identities = 31/117 (26%), Positives = 43/117 (36%), Gaps = 10/117 (8%)

Query: 3   KPQPLQQPSQPQQPPPTQQAVARRPPGGTSPPNGGLPG--PLATSAAPPGPPAAASPCLG 60
           KP+  QQP  P+ P       A   P   +P N  +PG  P  +   P  P    SP  G
Sbjct: 524 KPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSG 583

Query: 61  PVAAAGS------GLRRGAEGILAPQPPPPQQ--HQERPGAAAIGSARGQSTGKGPP 109
             + +G+      GL          QPP P++      PGA+   S     +    P
Sbjct: 584 YSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDP 640



 Score = 32.7 bits (73), Expect = 1.9
 Identities = 31/114 (27%), Positives = 42/114 (36%), Gaps = 17/114 (14%)

Query: 10  PSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAA----PPGPPAAASPCL-GPVAA 64
           PS+P+ P P   A+A             +PGP++T+ A    PP P    +P    PV +
Sbjct: 674 PSKPRSPNPAAPALAAPAV---------VPGPVSTTDASPQSPPTPQTTLTPLQESPVIS 724

Query: 65  AGSGLRRGAEGILAPQPPP---PQQHQERPGAAAIGSARGQSTGKGPPQSPVFE 115
                         P PPP   P+   E P A+       Q     PP  P  E
Sbjct: 725 KDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPE 778



 Score = 30.8 bits (68), Expect = 7.1
 Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 5/80 (6%)

Query: 33  PPNGGLPGPLATSAAPPGPPAAASPCL-GPVAAAGSGLRRGAEGILAPQPPPPQQHQERP 91
           PP+  +P P +   + P  P  A+P L  P    G      A    +PQ PP  Q    P
Sbjct: 661 PPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDA----SPQSPPTPQTTLTP 716

Query: 92  GAAAIGSARGQSTGKGPPQS 111
              +   ++ QS    PP S
Sbjct: 717 LQESPVISKDQSPPPSPPPS 736


>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 [Homo
            sapiens]
          Length = 2231

 Score = 71.6 bits (174), Expect = 4e-12
 Identities = 133/524 (25%), Positives = 182/524 (34%), Gaps = 108/524 (20%)

Query: 574  EEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG 633
            + P G    ++ LLTS    SP+  ++   S  E   P AP      P+       +  G
Sbjct: 352  QHPSGATPTLNQLLTSP---SPMM-RSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407

Query: 634  SPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGP---RTH 690
                    G  KD G  A+    S     A++   + P +S       P +PGP   R+ 
Sbjct: 408  GQQAAAGMGLGKDMG--AQYAAASPAWAAAQQ--RSHPAMS-------PGTPGPTMGRSQ 456

Query: 691  STPSIPVLTA-------GQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK 743
             +P  P++         G +    PQ  S  P    GP    PQ YP  +    PG    
Sbjct: 457  GSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPP--GPQRYPIGIQGRTPGAMAG 514

Query: 744  YRGAKGSLPPQR-----------------SDQHQPASAPPMMQAAAAAGPPLVAATPYSS 786
             +  +  +PPQ                  S Q QP   PP  Q                 
Sbjct: 515  MQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQ----------------- 557

Query: 787  YIPYNPQQ-FPGQPAMMQPMAHYPSQPVFAPMLQSNPRM-LTSGSHPQAIVSSSTPQYPS 844
            Y+P   QQ +  Q  M Q      SQP  AP   ++  + L     P     SS P    
Sbjct: 558  YLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERP-----SSLPDLSG 612

Query: 845  AEQPTPQALYATVHQSY-PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPH 903
            +    P    AT+  +     +T     Q  PA +P      S HA+P       G +P 
Sbjct: 613  SIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPF-----SPHASPHLSSIPGGPSPS 667

Query: 904  -----LGSGQPQQNLYHPGALTGTP-PSLPPGPSAQSPQSSFPQPAAVYAIHHQQLP--H 955
                 +GS Q +     P ++ G+  P  PPG  +QS  SS P      A+    +P   
Sbjct: 668  PVGSPVGSNQSRSGPISPASIPGSQMPPQPPG--SQSESSSHP------ALSQSPMPQER 719

Query: 956  GF-----TNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHG--GP------PQ 1002
            GF      N         QTG + +P P PG      +       S G  GP      PQ
Sbjct: 720  GFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQ 779

Query: 1003 GAVPQ----SGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGA 1042
            G   +    SGVP+ S S P P   I     +  GQ P  P GA
Sbjct: 780  GNYSRPPAYSGVPSASYSGPGPGMGIS-ANNQMHGQGPSQPCGA 822



 Score = 63.9 bits (154), Expect = 8e-10
 Identities = 163/776 (21%), Positives = 252/776 (32%), Gaps = 105/776 (13%)

Query: 321  RTEEEKHSAVQRQGSGRESPSLASREGKYIPLPQRVREGPRGGVRCSSSRGGRPGLSSLP 380
            R  +E  +AV +  +     S  SR+G +  + Q        G+  SSS   +P  +S  
Sbjct: 869  RKAQEAAAAVMQAAAN----SAQSRQGSFPGMNQ-------SGLMASSSPYSQPMNNS-- 915

Query: 381  PRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA 440
                  L N+   P S A  +    +     A     G   L  P      E   P P +
Sbjct: 916  ----SSLMNTQAPPYSMAPAMVNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPES 971

Query: 441  VGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKIS 500
              +        S  P P +   P P   S+   SS     + S+S PG    +P+SPK S
Sbjct: 972  KSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDESDSISSPGWPK-TPSSPKSS 1030

Query: 501  LAPTDVKELST-----KEPGRTL------------------------EPQELARI---AG 528
             + T  ++++       EP R L                        +P +L R+     
Sbjct: 1031 SSTTTGEKITKVYELGNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVK 1090

Query: 529  KVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLT 588
            ++ GL    K    ++ R+      +  SSS  +SL              K++ +  L  
Sbjct: 1091 EIGGLAQVNKN---KKWRELATNLNVGTSSSAASSL--------------KKQYIQYLFA 1133

Query: 589  SE---PMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDK 645
             E     G     +  S  D + +P L P           P  P  TGS  +  + G+ K
Sbjct: 1134 FECKIERGEEPPPEVFSTGDTKKQPKLQPPSPANSGSLQGPQTPQSTGSNSMAEVPGDLK 1193

Query: 646  DEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNK--STSTPTSPGPRTHSTPSIPVLTAGQS 703
               P +    + T     +        +SV+   S  + +S   R   TP+ P     Q 
Sbjct: 1194 PPTPASTPHGQMTPMQGGR-----SSTISVHDPFSDVSDSSFPKRNSMTPNAPY----QQ 1244

Query: 704  GLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLP-PQRSDQHQPA 762
            G+  P  +  +P          P   P+     VPG    +   +G +P     D +  +
Sbjct: 1245 GMSMPDVMGRMP--------YEPNKDPFGGMRKVPGSSEPFM-TQGQMPNSSMQDMYNQS 1295

Query: 763  SAPPMMQAAAAAGPPLVAATPYS-SYIPYNPQQFPGQ-PAMMQPMAHYPSQPVFAPMLQS 820
             +  M                Y   + PY  QQ+PGQ P   QP  +   QP   P  Q 
Sbjct: 1296 PSGAMSNLGMGQRQQFPYGASYDRRHEPYG-QQYPGQGPPSGQP-PYGGHQPGLYPQ-QP 1352

Query: 821  NPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALYATVHQSYP-HHATQLHAHQPQPATTP 879
            N +    G +           Y        Q +Y     SY       +    P P +  
Sbjct: 1353 NYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYSRE 1412

Query: 880  TGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSF 939
                P        P Q   G      S  PQQN++        P     GP   +    +
Sbjct: 1413 RMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNMWAARNDMPYPYQNRQGPGGPTQAPPY 1472

Query: 940  P--QPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSH 997
            P         +  Q++ H     +HV+Q       +A+  P      PPQ     PP   
Sbjct: 1473 PGMNRTDDMMVPDQRINHESQWPSHVSQRQPYMSSSASMQP---ITRPPQPSYQTPPSLP 1529

Query: 998  GGPPQGAVPQSGVPAL-SASTPSPYPYIGHPQGEQPGQAPGFPGGADDRIPPLPPP 1052
                +   P S   +L +  +PS  P++  P  +     P  P       PP PPP
Sbjct: 1530 NHISRAPSPASFQRSLENRMSPSKSPFL--PSMKMQKVMPTVPTSQVTGPPPQPPP 1583



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 138/618 (22%), Positives = 188/618 (30%), Gaps = 155/618 (25%)

Query: 533  LQNEQKRFQLEELRKFGAQFKLQPSSSP---ENSLD------PFPPRILKEEPKGKEKEV 583
            LQ +  +FQ ++ ++   Q + Q    P    NSL       P P   +++   G  K+ 
Sbjct: 48   LQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDS 107

Query: 584  DGLLTSEPMGSPVSSKTESVSDKEDKPPLA----------PSGGTEGPEQPPPPCPSQTG 633
                 ++P G P+ SK     D++D PP            P  G  G +QPP   P   G
Sbjct: 108  AAGGQADPPGPPLLSKP---GDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGG 164

Query: 634  SPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTP 693
                          GP A             EFN           ++ P S GP   + P
Sbjct: 165  --------------GPAA-----------VPEFNNYY-------GSAAPASGGPGGRAGP 192

Query: 694  SIPV----LTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQ-------- 741
                     + G   ++S    +      M P   + + YP    N  PG          
Sbjct: 193  CFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGG 252

Query: 742  -------GKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSY---IPYN 791
                   G   G  G            A A     AAAAAG         SS    +  +
Sbjct: 253  GGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSS 312

Query: 792  PQQFPGQPAMMQPM---AHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQP 848
            P+Q  G   MM P    A   S+           R      HP    S +TP        
Sbjct: 313  PRQ-QGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHP----SGATPTLNQL-LT 366

Query: 849  TPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQ 908
            +P  +  +   SYP +++         A  P  SQPQSQ AA          A  +G G+
Sbjct: 367  SPSPMMRSYGGSYPEYSSP-------SAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGK 419

Query: 909  PQ--------------QNLYHPGALTGTP-PSL------PPGPSA--------------Q 933
                            Q   HP    GTP P++      P  P                 
Sbjct: 420  DMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHS 479

Query: 934  SPQSSFPQPAAVYA-IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPH------------- 979
             PQ S P P   Y     Q+ P G         A +Q      PP +             
Sbjct: 480  QPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQ 539

Query: 980  -------PGAPH-PPQVMLLHPPQSHGGPPQGAVPQSGV-----PALSASTPSPYPYIGH 1026
                   P  PH PPQ   L         PQ  + Q G      P L+   P+ +  +  
Sbjct: 540  QPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPN-HEDLNL 598

Query: 1027 PQGEQPGQAPGFPGGADD 1044
             Q E+P   P   G  DD
Sbjct: 599  IQQERPSSLPDLSGSIDD 616



 Score = 32.7 bits (73), Expect = 1.9
 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 8/80 (10%)

Query: 380  PPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPP- 438
            PP  P+H+  + P P S  R +    +RMSP     L   K        P+ + + PPP 
Sbjct: 1525 PPSLPNHISRA-PSPASFQRSLE---NRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQ 1580

Query: 439  -PAVGR--MYPPRSPKSAAP 455
             P + R   +PP S +++ P
Sbjct: 1581 PPPIRREITFPPGSVEASQP 1600



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 40/135 (29%), Positives = 45/135 (33%), Gaps = 26/135 (19%)

Query: 5   QPLQQPSQPQQPPPTQQAVARRPPGGT--------SPPNGGLPGPLATSAA-PPGPPAA- 54
           Q  QQ  Q QQ P +         GG          P +GG     A   A PPGPP   
Sbjct: 63  QQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS 122

Query: 55  -------ASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAI-------GSAR 100
                  A P +G    AG        G L  Q PP        G AA+       GSA 
Sbjct: 123 KPGDEDDAPPKMG--EPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA 180

Query: 101 GQSTGKGPPQSPVFE 115
             S G G    P F+
Sbjct: 181 PASGGPGGRAGPCFD 195



 Score = 31.6 bits (70), Expect = 4.2
 Identities = 31/114 (27%), Positives = 39/114 (34%), Gaps = 9/114 (7%)

Query: 9   QPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGP-------PAAASPCLGP 61
           Q   P    PT   +   P        G  P   + SA PP P        AA +   G 
Sbjct: 350 QNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQ 409

Query: 62  VAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK--GPPQSPV 113
            AAAG GL +      A   P     Q+R   A      G + G+  G P  P+
Sbjct: 410 QAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPM 463



 Score = 30.8 bits (68), Expect = 7.1
 Identities = 21/70 (30%), Positives = 29/70 (41%), Gaps = 4/70 (5%)

Query: 36  GGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGIL----APQPPPPQQHQERP 91
           G   G     A     P+ A+P L  +  + S + R   G      +P  PPP   Q + 
Sbjct: 338 GSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQS 397

Query: 92  GAAAIGSARG 101
            AAA G+A G
Sbjct: 398 QAAAAGAAAG 407


>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 [Homo
            sapiens]
          Length = 2178

 Score = 71.6 bits (174), Expect = 4e-12
 Identities = 133/524 (25%), Positives = 182/524 (34%), Gaps = 108/524 (20%)

Query: 574  EEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG 633
            + P G    ++ LLTS    SP+  ++   S  E   P AP      P+       +  G
Sbjct: 352  QHPSGATPTLNQLLTSP---SPMM-RSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAG 407

Query: 634  SPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGP---RTH 690
                    G  KD G  A+    S     A++   + P +S       P +PGP   R+ 
Sbjct: 408  GQQAAAGMGLGKDMG--AQYAAASPAWAAAQQ--RSHPAMS-------PGTPGPTMGRSQ 456

Query: 691  STPSIPVLTA-------GQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK 743
             +P  P++         G +    PQ  S  P    GP    PQ YP  +    PG    
Sbjct: 457  GSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPP--GPQRYPIGIQGRTPGAMAG 514

Query: 744  YRGAKGSLPPQR-----------------SDQHQPASAPPMMQAAAAAGPPLVAATPYSS 786
             +  +  +PPQ                  S Q QP   PP  Q                 
Sbjct: 515  MQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQ----------------- 557

Query: 787  YIPYNPQQ-FPGQPAMMQPMAHYPSQPVFAPMLQSNPRM-LTSGSHPQAIVSSSTPQYPS 844
            Y+P   QQ +  Q  M Q      SQP  AP   ++  + L     P     SS P    
Sbjct: 558  YLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERP-----SSLPDLSG 612

Query: 845  AEQPTPQALYATVHQSY-PHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPH 903
            +    P    AT+  +     +T     Q  PA +P      S HA+P       G +P 
Sbjct: 613  SIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPF-----SPHASPHLSSIPGGPSPS 667

Query: 904  -----LGSGQPQQNLYHPGALTGTP-PSLPPGPSAQSPQSSFPQPAAVYAIHHQQLP--H 955
                 +GS Q +     P ++ G+  P  PPG  +QS  SS P      A+    +P   
Sbjct: 668  PVGSPVGSNQSRSGPISPASIPGSQMPPQPPG--SQSESSSHP------ALSQSPMPQER 719

Query: 956  GF-----TNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHG--GP------PQ 1002
            GF      N         QTG + +P P PG      +       S G  GP      PQ
Sbjct: 720  GFMAGTQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQ 779

Query: 1003 GAVPQ----SGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGA 1042
            G   +    SGVP+ S S P P   I     +  GQ P  P GA
Sbjct: 780  GNYSRPPAYSGVPSASYSGPGPGMGIS-ANNQMHGQGPSQPCGA 822



 Score = 57.4 bits (137), Expect = 7e-08
 Identities = 174/802 (21%), Positives = 264/802 (32%), Gaps = 113/802 (14%)

Query: 331  QRQGSGRESPSLA--------SREGKYIPLPQRVREGPRGGVRCSSSRG----------G 372
            Q   SG   P ++        SR   Y  +P     GP  G+  S++            G
Sbjct: 762  QSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCG 821

Query: 373  RPGLSSLPPRG----PHHLDNSSPGPGSEARGINGGPSRMSP------KAQRPLRGAKTL 422
               L  +P  G    P   + SS  P S      GGP    P      KAQ     A   
Sbjct: 822  AVPLGRMPSAGMQNRPFPGNMSSMTPSSPGMSQQGGPGMGPPMPTVNRKAQEAA-AAVMQ 880

Query: 423  SSPSNRPSGETSVPPPPAVGRMY---PPRSPKSAAPAPISASCPEPPIGSAVPTSSASIP 479
            ++ ++  S + S P     G M    P   P + + + ++   P        P S A   
Sbjct: 881  AAANSAQSRQGSFPGMNQSGLMASSSPYSQPMNNSSSLMNTQAP--------PYSMAPAM 932

Query: 480  VTSSVSDPGVGSI-SPASPKISLA-PTDVKELSTKEPGRTLEPQELARIAG----KVPGL 533
            V SS +  G+  + SP   K+ L    D KE  T +P    +    +   G    KV  L
Sbjct: 933  VNSSAASVGLADMMSPGESKLPLPLKADGKEEGTPQPESKSKKSSSSTTTGEKITKVYEL 992

Query: 534  QNE-QKRFQLEELRKFGAQFKLQPSSSP---ENSLDPFPPRILKEEPKG-----KEKEVD 584
             NE +++  ++    F  +     SS P   +  LD F   +  +E  G     K K+  
Sbjct: 993  GNEPERKLWVDRYLTFMEERGSPVSSLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWR 1052

Query: 585  GLLTSEPMGSPVSSKTE--------------SVSDKEDKPP-LAPSGGTEGPEQPPPPCP 629
             L T+  +G+  S+ +                +   E+ PP +  +G T+   +  PP P
Sbjct: 1053 ELATNLNVGTSSSAASSLKKQYIQYLFAFECKIERGEEPPPEVFSTGDTKKQPKLQPPSP 1112

Query: 630  SQTGS---PPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSP- 685
            + +GS   P      G +     V   +K  T  P +       P+     ST +   P 
Sbjct: 1113 ANSGSLQGPQTPQSTGSN-SMAEVPGDLKPPT--PASTPHGQMTPMQGGRSSTISVHDPF 1169

Query: 686  --------GPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSV 737
                      R   TP+ P     Q G+  P  +  +P          P   P+     V
Sbjct: 1170 SDVSDSSFPKRNSMTPNAPY----QQGMSMPDVMGRMP--------YEPNKDPFGGMRKV 1217

Query: 738  PGQQGKYRGAKGSLP-PQRSDQHQPASAPPMMQAAAAAGPPLVAATPYS-SYIPYNPQQF 795
            PG    +   +G +P     D +  + +  M                Y   + PY  QQ+
Sbjct: 1218 PGSSEPFM-TQGQMPNSSMQDMYNQSPSGAMSNLGMGQRQQFPYGASYDRRHEPYG-QQY 1275

Query: 796  PGQ-PAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQPTPQALY 854
            PGQ P   QP  +   QP   P  Q N +    G +           Y        Q +Y
Sbjct: 1276 PGQGPPSGQP-PYGGHQPGLYPQ-QPNYKRHMDGMYGPPAKRHEGDMYNMQYSSQQQEMY 1333

Query: 855  ATVHQSYP-HHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNL 913
                 SY       +    P P +      P        P Q   G      S  PQQN+
Sbjct: 1334 NQYGGSYSGPDRRPIQGQYPYPYSRERMQGPGQIQTHGIPPQMMGGPLQSSSSEGPQQNM 1393

Query: 914  YHPGALTGTPPSLPPGPSAQSPQSSFP--QPAAVYAIHHQQLPHGFTNMAHVTQAHVQTG 971
            +        P     GP   +    +P         +  Q++ H     +HV+Q      
Sbjct: 1394 WAARNDMPYPYQNRQGPGGPTQAPPYPGMNRTDDMMVPDQRINHESQWPSHVSQRQPYMS 1453

Query: 972  ITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPAL-SASTPSPYPYIGHPQGE 1030
             +A+  P      PPQ     PP       +   P S   +L +  +PS  P++  P  +
Sbjct: 1454 SSASMQP---ITRPPQPSYQTPPSLPNHISRAPSPASFQRSLENRMSPSKSPFL--PSMK 1508

Query: 1031 QPGQAPGFPGGADDRIPPLPPP 1052
                 P  P       PP PPP
Sbjct: 1509 MQKVMPTVPTSQVTGPPPQPPP 1530



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 138/618 (22%), Positives = 188/618 (30%), Gaps = 155/618 (25%)

Query: 533  LQNEQKRFQLEELRKFGAQFKLQPSSSP---ENSLD------PFPPRILKEEPKGKEKEV 583
            LQ +  +FQ ++ ++   Q + Q    P    NSL       P P   +++   G  K+ 
Sbjct: 48   LQQQLNQFQQQQQQQQQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDS 107

Query: 584  DGLLTSEPMGSPVSSKTESVSDKEDKPPLA----------PSGGTEGPEQPPPPCPSQTG 633
                 ++P G P+ SK     D++D PP            P  G  G +QPP   P   G
Sbjct: 108  AAGGQADPPGPPLLSKP---GDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGG 164

Query: 634  SPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTP 693
                          GP A             EFN           ++ P S GP   + P
Sbjct: 165  --------------GPAA-----------VPEFNNYY-------GSAAPASGGPGGRAGP 192

Query: 694  SIPV----LTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQ-------- 741
                     + G   ++S    +      M P   + + YP    N  PG          
Sbjct: 193  CFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGG 252

Query: 742  -------GKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSY---IPYN 791
                   G   G  G            A A     AAAAAG         SS    +  +
Sbjct: 253  GGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSS 312

Query: 792  PQQFPGQPAMMQPM---AHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQP 848
            P+Q  G   MM P    A   S+           R      HP    S +TP        
Sbjct: 313  PRQ-QGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHP----SGATPTLNQL-LT 366

Query: 849  TPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQ 908
            +P  +  +   SYP +++         A  P  SQPQSQ AA          A  +G G+
Sbjct: 367  SPSPMMRSYGGSYPEYSSP-------SAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGK 419

Query: 909  PQ--------------QNLYHPGALTGTP-PSL------PPGPSA--------------Q 933
                            Q   HP    GTP P++      P  P                 
Sbjct: 420  DMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGSNPHS 479

Query: 934  SPQSSFPQPAAVYA-IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPH------------- 979
             PQ S P P   Y     Q+ P G         A +Q      PP +             
Sbjct: 480  QPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQ 539

Query: 980  -------PGAPH-PPQVMLLHPPQSHGGPPQGAVPQSGV-----PALSASTPSPYPYIGH 1026
                   P  PH PPQ   L         PQ  + Q G      P L+   P+ +  +  
Sbjct: 540  QPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPN-HEDLNL 598

Query: 1027 PQGEQPGQAPGFPGGADD 1044
             Q E+P   P   G  DD
Sbjct: 599  IQQERPSSLPDLSGSIDD 616



 Score = 32.7 bits (73), Expect = 1.9
 Identities = 24/80 (30%), Positives = 37/80 (46%), Gaps = 8/80 (10%)

Query: 380  PPRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPP- 438
            PP  P+H+  + P P S  R +    +RMSP     L   K        P+ + + PPP 
Sbjct: 1472 PPSLPNHISRA-PSPASFQRSLE---NRMSPSKSPFLPSMKMQKVMPTVPTSQVTGPPPQ 1527

Query: 439  -PAVGR--MYPPRSPKSAAP 455
             P + R   +PP S +++ P
Sbjct: 1528 PPPIRREITFPPGSVEASQP 1547



 Score = 32.3 bits (72), Expect = 2.4
 Identities = 40/135 (29%), Positives = 45/135 (33%), Gaps = 26/135 (19%)

Query: 5   QPLQQPSQPQQPPPTQQAVARRPPGGT--------SPPNGGLPGPLATSAA-PPGPPAA- 54
           Q  QQ  Q QQ P +         GG          P +GG     A   A PPGPP   
Sbjct: 63  QQQQQQQQQQQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLS 122

Query: 55  -------ASPCLGPVAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAI-------GSAR 100
                  A P +G    AG        G L  Q PP        G AA+       GSA 
Sbjct: 123 KPGDEDDAPPKMG--EPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAA 180

Query: 101 GQSTGKGPPQSPVFE 115
             S G G    P F+
Sbjct: 181 PASGGPGGRAGPCFD 195



 Score = 31.6 bits (70), Expect = 4.2
 Identities = 31/114 (27%), Positives = 39/114 (34%), Gaps = 9/114 (7%)

Query: 9   QPSQPQQPPPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGP-------PAAASPCLGP 61
           Q   P    PT   +   P        G  P   + SA PP P        AA +   G 
Sbjct: 350 QNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQ 409

Query: 62  VAAAGSGLRRGAEGILAPQPPPPQQHQERPGAAAIGSARGQSTGK--GPPQSPV 113
            AAAG GL +      A   P     Q+R   A      G + G+  G P  P+
Sbjct: 410 QAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPM 463



 Score = 30.8 bits (68), Expect = 7.1
 Identities = 21/70 (30%), Positives = 29/70 (41%), Gaps = 4/70 (5%)

Query: 36  GGLPGPLATSAAPPGPPAAASPCLGPVAAAGSGLRRGAEGIL----APQPPPPQQHQERP 91
           G   G     A     P+ A+P L  +  + S + R   G      +P  PPP   Q + 
Sbjct: 338 GSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQS 397

Query: 92  GAAAIGSARG 101
            AAA G+A G
Sbjct: 398 QAAAAGAAAG 407


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 128/566 (22%), Positives = 197/566 (34%), Gaps = 71/566 (12%)

Query: 394 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRP------SGETSVPPPPAVGRMYPP 447
           P  +A     GP+  +PK   P    +  S+    P      S  T+   P        P
Sbjct: 197 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 256

Query: 448 RSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVK 507
            +PK  AP       P  P   A  T+    P T+  +       +P +PK   APT   
Sbjct: 257 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPT--- 312

Query: 508 ELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPF 567
             + KEP  T  P+E      K P    ++      +     A  K  P++  E +    
Sbjct: 313 --TPKEPAPT-TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA---- 365

Query: 568 PPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP 627
            P   KE      KE       EP  +P ++K+   + KE     AP+     P  P  P
Sbjct: 366 -PTTPKEPAPTTTKEPSPTTPKEP--APTTTKSAPTTTKEP----APTTTKSAPTTPKEP 418

Query: 628 CPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNK--STSTPTSP 685
            P+ T  P         K+  P   +    T         P +P  +  K  + +TP  P
Sbjct: 419 SPTTTKEP----APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 474

Query: 686 GPRT--HSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK 743
            P T   + P+ P          +P+ ++  P     PA   P+     ++ + P +   
Sbjct: 475 APTTPKETAPTTPKKLTPT----TPEKLA--PTTPEKPAPTTPE----ELAPTTPEE--- 521

Query: 744 YRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQ 803
                    P  +   +PA   P  +AAA   P   A T      P  P+    +PA   
Sbjct: 522 ---------PTPTTPEEPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPK----EPAPTT 566

Query: 804 PMAHYPSQPV-FAPMLQSNPRMLT-SGSHPQAIVSSST--PQYPSAEQPTPQALYATVHQ 859
           P    P+ P   AP     P   T     P+ +  ++T  P   + ++P P     T   
Sbjct: 567 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA-P 625

Query: 860 SYPHHATQLHAHQPQPATTPTGSQPQS-QHAAPSPVQHQAGQ--APHLGSGQPQQNLYHP 916
           + P         +P P TTP G+ P + +  AP+  +  A +  AP    G        P
Sbjct: 626 TTPKEPAPTTPKEPAP-TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 684

Query: 917 GALT--GTPPSLPPGPSAQSPQSSFP 940
              T   T P+ P  P+  +P+   P
Sbjct: 685 APTTPKETAPTTPKEPAPTTPKKPAP 710



 Score = 67.8 bits (164), Expect = 5e-11
 Identities = 124/579 (21%), Positives = 183/579 (31%), Gaps = 72/579 (12%)

Query: 419 AKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASI 478
           +K L+ P+  P  ET+   P     +  P+ P    P   +++ P+ P     PT+  S 
Sbjct: 191 SKVLAKPT--PKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEP----TPTTIKSA 240

Query: 479 PVTSSVSDPGVGSISPASPKISLAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQN 535
           P T            PA      APT  KE    +TKEP  T  P+E A    K P    
Sbjct: 241 PTTPK---------EPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKEPA--- 287

Query: 536 EQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSP 595
                                 S+P    +P P    K  P    KE       EP  +P
Sbjct: 288 -----------------PTTTKSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEP--TP 327

Query: 596 VSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG-SPPVGLIKGEDKDEGPVAEQV 654
            + K  + + KE  P          P++P P  P +   + P        K+  P   + 
Sbjct: 328 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 387

Query: 655 KKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYI 714
              T   +A          +   + +TP  P P T   P+    T  +    +P+     
Sbjct: 388 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTTPK--KPA 443

Query: 715 PQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAA 774
           P     PA   P+  P P +   P        A  + P + +        P   +  A  
Sbjct: 444 PTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTPEKLAPT 501

Query: 775 GPPLVAATPYSSYIPYNPQQ----FPGQPAMMQPMAHYPSQPVF-APMLQSNPRMLTSGS 829
            P   A T      P  P++     P +PA   P A  P+ P   AP     P   T   
Sbjct: 502 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 561

Query: 830 HPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHA 889
                   + P  P    PT      T+ +  P    +    +  P TT   +       
Sbjct: 562 PAPTTPKETAPTTPKGTAPT------TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 615

Query: 890 APSPVQHQAGQAPHLGSGQPQQNLYHPGALT--GTPPSLPPGPSAQSPQSSFPQPAAVYA 947
           AP+  +   G AP             P   T  GT P+    P+  +P+   P+  A   
Sbjct: 616 APTTPK---GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 672

Query: 948 IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPP 986
               + P   T+         +T  T    P P  P  P
Sbjct: 673 ---TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP 708



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 107/502 (21%), Positives = 162/502 (32%), Gaps = 67/502 (13%)

Query: 406 SRMSPKAQRPLRGAKTLSSPSN--RPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCP 463
           ++ +P   +      T S+P+    PS  T+  P P   +   P +PK  AP       P
Sbjct: 393 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 452

Query: 464 EPPIGSAVPTSSASIPVTSSVSDPGV-GSISPASPKISLAPTDVKEL--STKEPGRTLEP 520
             P   A  T+    P T     P      +P +PK  L PT  ++L  +T E      P
Sbjct: 453 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTP 511

Query: 521 QELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFP-------PRILK 573
           +ELA    + P     ++                  +++P    +P P       P   K
Sbjct: 512 EELAPTTPEEPTPTTPEEPAP-----------TTPKAAAPNTPKEPAPTTPKEPAPTTPK 560

Query: 574 EEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG 633
           E      KE      + P G+  ++  E       KP       T   E     C     
Sbjct: 561 EPAPTTPKET---APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 617

Query: 634 SPPVGLIKGEDKDEGPV-----AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPR 688
           + P G      K+  P      A    K T     KE  PT P     K  +  T+ GP 
Sbjct: 618 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP- 676

Query: 689 THSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAK 748
           T +T   P  T  +            P     PA   P+  P P +   P          
Sbjct: 677 TSTTSDKPAPTTPK---------ETAPTTPKEPAPTTPKK-PAPTTPETP---------- 716

Query: 749 GSLPPQRSDQHQPASA--PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMA 806
              PP  S+   P +   P  +  +     P ++A P    +  +P++ PG P    P A
Sbjct: 717 ---PPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE-PGVPTTKTPAA 772

Query: 807 HYPSQPVFAP------MLQSNPRMLTSGSHPQAIVSSSTPQYPSAE--QPTPQALYATVH 858
             P     A        L++ P   T+        +++T +   ++    T Q    T  
Sbjct: 773 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 832

Query: 859 QSYPHHATQLHAHQPQPATTPT 880
            + P   T L      P  T T
Sbjct: 833 DTTPFKITTLKTTTLAPKVTTT 854



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 113/544 (20%), Positives = 176/544 (32%), Gaps = 67/544 (12%)

Query: 381 PRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA 440
           P+ P       P P +        P   +P  + P        +P+       + P  PA
Sbjct: 306 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 365

Query: 441 VGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKIS 500
                 P    +  P+P +   P        PT++ S P T+    P     +P +PK  
Sbjct: 366 PTTPKEPAPTTTKEPSPTTPKEP-------APTTTKSAPTTTKEPAPTTTKSAPTTPK-E 417

Query: 501 LAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPS 557
            +PT  KE    + KEP  T  P++ A    K P     ++       +      K    
Sbjct: 418 PSPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 476

Query: 558 SSPENSLDPFPPRILKEEPK---GKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAP 614
           ++P+ +    P ++    P+       E     T E +      +    + +E  P    
Sbjct: 477 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 536

Query: 615 SGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGP--VAEQVKKSTLNPNAKEFNPTKPL 672
           +     P++P P  P +    P      E     P   A    K T     KE  PT P 
Sbjct: 537 AAAPNTPKEPAPTTPKE----PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 592

Query: 673 LSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP 732
               K  +  T+  P T +T   P                  P    G A   P+  P P
Sbjct: 593 KPAPKELAPTTTKEP-TSTTCDKPA-----------------PTTPKGTAPTTPK-EPAP 633

Query: 733 VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLV---AATPYSSYIP 789
            +   P         KG+ P   +   +PA   P   A     P       +T      P
Sbjct: 634 TTPKEPAP----TTPKGTAP---TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 686

Query: 790 YNPQQ----FPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSS---STPQY 842
             P++     P +PA   P    P+ P   P   S     T+   P  I  S   STP+ 
Sbjct: 687 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 746

Query: 843 PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTG--------SQPQSQHAAPSPV 894
             + +PTP+AL  +  +          A +P+  TT           + P++  AAP   
Sbjct: 747 --SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 804

Query: 895 QHQA 898
           +  A
Sbjct: 805 KETA 808



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 73/315 (23%), Positives = 110/315 (34%), Gaps = 59/315 (18%)

Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464
           P+  +PK   P   A T +     P+  TS  P P   +   P +PK  AP       P 
Sbjct: 655 PAPTTPKKPAPKELAPTTTKG---PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 711

Query: 465 PPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPT-DVKELSTKEPGRTLEPQEL 523
            P      TS  S P T+        S   ++P++S  PT    E S KEPG    P   
Sbjct: 712 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG---VPTTK 768

Query: 524 ARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEV 583
              A K       + +    +LR           ++PE +     P++ KE     EK  
Sbjct: 769 TPAATKPEMTTTAKDKTTERDLR-----------TTPETT--TAAPKMTKETATTTEKTT 815

Query: 584 DGLLTSEPMGSPVSSKTESVSDKEDKP---------PLAPSGGT-----------EGPEQ 623
           +  +T+       +++  S + ++  P          LAP   T             PE+
Sbjct: 816 ESKITA------TTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEE 869

Query: 624 PPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP- 682
              P    T S          K   P  ++  K+   P + +   T P +   K+T TP 
Sbjct: 870 TAKPKDRATNS----------KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPR 919

Query: 683 --TSPGPRTHSTPSI 695
             TS  P  + T  I
Sbjct: 920 KMTSTMPELNPTSRI 934



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 102/472 (21%), Positives = 144/472 (30%), Gaps = 60/472 (12%)

Query: 589  SEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEG 648
            S P  S  S +T    +KE       +  T           + +      + K   KD  
Sbjct: 129  SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 188

Query: 649  PVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSP 708
            P ++ + K T  P A E     P L+  K   TPT+P     +TP  P          +P
Sbjct: 189  PTSKVLAKPT--PKA-ETTTKGPALTTPKEP-TPTTPKEPASTTPKEP----------TP 234

Query: 709  QYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMM 768
              I   P     PA    +  P     + P +            P  +   +PA   P  
Sbjct: 235  TTIKSAPTTPKEPAPTTTKSAP-----TTPKE------------PAPTTTKEPAPTTPKE 277

Query: 769  QAAAAAGPPLVAATPYSSYIPYNP-QQFPGQPAMMQPMAHYPSQPVF-APMLQSNPRMLT 826
             A      P    T  +   P  P    P +PA   P    P+ P    P     P   T
Sbjct: 278  PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 337

Query: 827  SGSHPQAIVSSSTPQYPSAEQP------TPQALYATVHQSYPHHATQLHAHQPQPATTPT 880
                P      +TP+ P+   P      TP+    T     P         +P P TTP 
Sbjct: 338  KEPAP------TTPKEPAPTAPKKPAPTTPKEPAPTT----PKEPAPTTTKEPSP-TTPK 386

Query: 881  GSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFP 940
               P +  +AP+  +  A          P++    P       P+ P  P+  +P+   P
Sbjct: 387  EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP--SPTTTKEPAPTTPKEPAPTTPKKPAP 444

Query: 941  QPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGP 1000
                  A    + P   T          +   T    P   AP  P+ +    P+    P
Sbjct: 445  TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTT---PKETAPTTPKKLTPTTPEKL-AP 500

Query: 1001 PQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRIPPLPPP 1052
                 P    P   A T    P    P  E+P  AP  P  A    P  P P
Sbjct: 501  TTPEKPAPTTPEELAPTTPEEPTPTTP--EEP--APTTPKAAAPNTPKEPAP 548


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 128/566 (22%), Positives = 197/566 (34%), Gaps = 71/566 (12%)

Query: 394 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRP------SGETSVPPPPAVGRMYPP 447
           P  +A     GP+  +PK   P    +  S+    P      S  T+   P        P
Sbjct: 238 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 297

Query: 448 RSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVK 507
            +PK  AP       P  P   A  T+    P T+  +       +P +PK   APT   
Sbjct: 298 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPT--- 353

Query: 508 ELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPF 567
             + KEP  T  P+E      K P    ++      +     A  K  P++  E +    
Sbjct: 354 --TPKEPAPT-TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA---- 406

Query: 568 PPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP 627
            P   KE      KE       EP  +P ++K+   + KE     AP+     P  P  P
Sbjct: 407 -PTTPKEPAPTTTKEPSPTTPKEP--APTTTKSAPTTTKEP----APTTTKSAPTTPKEP 459

Query: 628 CPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNK--STSTPTSP 685
            P+ T  P         K+  P   +    T         P +P  +  K  + +TP  P
Sbjct: 460 SPTTTKEP----APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 515

Query: 686 GPRT--HSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK 743
            P T   + P+ P          +P+ ++  P     PA   P+     ++ + P +   
Sbjct: 516 APTTPKETAPTTPKKLTPT----TPEKLA--PTTPEKPAPTTPE----ELAPTTPEE--- 562

Query: 744 YRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQ 803
                    P  +   +PA   P  +AAA   P   A T      P  P+    +PA   
Sbjct: 563 ---------PTPTTPEEPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPK----EPAPTT 607

Query: 804 PMAHYPSQPV-FAPMLQSNPRMLT-SGSHPQAIVSSST--PQYPSAEQPTPQALYATVHQ 859
           P    P+ P   AP     P   T     P+ +  ++T  P   + ++P P     T   
Sbjct: 608 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA-P 666

Query: 860 SYPHHATQLHAHQPQPATTPTGSQPQS-QHAAPSPVQHQAGQ--APHLGSGQPQQNLYHP 916
           + P         +P P TTP G+ P + +  AP+  +  A +  AP    G        P
Sbjct: 667 TTPKEPAPTTPKEPAP-TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 725

Query: 917 GALT--GTPPSLPPGPSAQSPQSSFP 940
              T   T P+ P  P+  +P+   P
Sbjct: 726 APTTPKETAPTTPKEPAPTTPKKPAP 751



 Score = 67.8 bits (164), Expect = 5e-11
 Identities = 124/579 (21%), Positives = 183/579 (31%), Gaps = 72/579 (12%)

Query: 419 AKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASI 478
           +K L+ P+  P  ET+   P     +  P+ P    P   +++ P+ P     PT+  S 
Sbjct: 232 SKVLAKPT--PKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEP----TPTTIKSA 281

Query: 479 PVTSSVSDPGVGSISPASPKISLAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQN 535
           P T            PA      APT  KE    +TKEP  T  P+E A    K P    
Sbjct: 282 PTTPK---------EPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKEPA--- 328

Query: 536 EQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSP 595
                                 S+P    +P P    K  P    KE       EP  +P
Sbjct: 329 -----------------PTTTKSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEP--TP 368

Query: 596 VSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG-SPPVGLIKGEDKDEGPVAEQV 654
            + K  + + KE  P          P++P P  P +   + P        K+  P   + 
Sbjct: 369 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 428

Query: 655 KKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYI 714
              T   +A          +   + +TP  P P T   P+    T  +    +P+     
Sbjct: 429 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTTPK--KPA 484

Query: 715 PQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAA 774
           P     PA   P+  P P +   P        A  + P + +        P   +  A  
Sbjct: 485 PTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTPEKLAPT 542

Query: 775 GPPLVAATPYSSYIPYNPQQ----FPGQPAMMQPMAHYPSQPVF-APMLQSNPRMLTSGS 829
            P   A T      P  P++     P +PA   P A  P+ P   AP     P   T   
Sbjct: 543 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 602

Query: 830 HPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHA 889
                   + P  P    PT      T+ +  P    +    +  P TT   +       
Sbjct: 603 PAPTTPKETAPTTPKGTAPT------TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 656

Query: 890 APSPVQHQAGQAPHLGSGQPQQNLYHPGALT--GTPPSLPPGPSAQSPQSSFPQPAAVYA 947
           AP+  +   G AP             P   T  GT P+    P+  +P+   P+  A   
Sbjct: 657 APTTPK---GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 713

Query: 948 IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPP 986
               + P   T+         +T  T    P P  P  P
Sbjct: 714 ---TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP 749



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 107/502 (21%), Positives = 162/502 (32%), Gaps = 67/502 (13%)

Query: 406 SRMSPKAQRPLRGAKTLSSPSN--RPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCP 463
           ++ +P   +      T S+P+    PS  T+  P P   +   P +PK  AP       P
Sbjct: 434 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 493

Query: 464 EPPIGSAVPTSSASIPVTSSVSDPGV-GSISPASPKISLAPTDVKEL--STKEPGRTLEP 520
             P   A  T+    P T     P      +P +PK  L PT  ++L  +T E      P
Sbjct: 494 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTP 552

Query: 521 QELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFP-------PRILK 573
           +ELA    + P     ++                  +++P    +P P       P   K
Sbjct: 553 EELAPTTPEEPTPTTPEEPAP-----------TTPKAAAPNTPKEPAPTTPKEPAPTTPK 601

Query: 574 EEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG 633
           E      KE      + P G+  ++  E       KP       T   E     C     
Sbjct: 602 EPAPTTPKET---APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 658

Query: 634 SPPVGLIKGEDKDEGPV-----AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPR 688
           + P G      K+  P      A    K T     KE  PT P     K  +  T+ GP 
Sbjct: 659 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP- 717

Query: 689 THSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAK 748
           T +T   P  T  +            P     PA   P+  P P +   P          
Sbjct: 718 TSTTSDKPAPTTPK---------ETAPTTPKEPAPTTPKK-PAPTTPETP---------- 757

Query: 749 GSLPPQRSDQHQPASA--PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMA 806
              PP  S+   P +   P  +  +     P ++A P    +  +P++ PG P    P A
Sbjct: 758 ---PPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE-PGVPTTKTPAA 813

Query: 807 HYPSQPVFAP------MLQSNPRMLTSGSHPQAIVSSSTPQYPSAE--QPTPQALYATVH 858
             P     A        L++ P   T+        +++T +   ++    T Q    T  
Sbjct: 814 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 873

Query: 859 QSYPHHATQLHAHQPQPATTPT 880
            + P   T L      P  T T
Sbjct: 874 DTTPFKITTLKTTTLAPKVTTT 895



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 113/544 (20%), Positives = 176/544 (32%), Gaps = 67/544 (12%)

Query: 381 PRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA 440
           P+ P       P P +        P   +P  + P        +P+       + P  PA
Sbjct: 347 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 406

Query: 441 VGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKIS 500
                 P    +  P+P +   P        PT++ S P T+    P     +P +PK  
Sbjct: 407 PTTPKEPAPTTTKEPSPTTPKEP-------APTTTKSAPTTTKEPAPTTTKSAPTTPK-E 458

Query: 501 LAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPS 557
            +PT  KE    + KEP  T  P++ A    K P     ++       +      K    
Sbjct: 459 PSPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 517

Query: 558 SSPENSLDPFPPRILKEEPK---GKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAP 614
           ++P+ +    P ++    P+       E     T E +      +    + +E  P    
Sbjct: 518 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 577

Query: 615 SGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGP--VAEQVKKSTLNPNAKEFNPTKPL 672
           +     P++P P  P +    P      E     P   A    K T     KE  PT P 
Sbjct: 578 AAAPNTPKEPAPTTPKE----PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 633

Query: 673 LSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP 732
               K  +  T+  P T +T   P                  P    G A   P+  P P
Sbjct: 634 KPAPKELAPTTTKEP-TSTTCDKPA-----------------PTTPKGTAPTTPK-EPAP 674

Query: 733 VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLV---AATPYSSYIP 789
            +   P         KG+ P   +   +PA   P   A     P       +T      P
Sbjct: 675 TTPKEPAP----TTPKGTAP---TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 727

Query: 790 YNPQQ----FPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSS---STPQY 842
             P++     P +PA   P    P+ P   P   S     T+   P  I  S   STP+ 
Sbjct: 728 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 787

Query: 843 PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTG--------SQPQSQHAAPSPV 894
             + +PTP+AL  +  +          A +P+  TT           + P++  AAP   
Sbjct: 788 --SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 845

Query: 895 QHQA 898
           +  A
Sbjct: 846 KETA 849



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 73/315 (23%), Positives = 110/315 (34%), Gaps = 59/315 (18%)

Query: 405 PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464
           P+  +PK   P   A T +     P+  TS  P P   +   P +PK  AP       P 
Sbjct: 696 PAPTTPKKPAPKELAPTTTKG---PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 752

Query: 465 PPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPT-DVKELSTKEPGRTLEPQEL 523
            P      TS  S P T+        S   ++P++S  PT    E S KEPG    P   
Sbjct: 753 TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG---VPTTK 809

Query: 524 ARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEV 583
              A K       + +    +LR           ++PE +     P++ KE     EK  
Sbjct: 810 TPAATKPEMTTTAKDKTTERDLR-----------TTPETT--TAAPKMTKETATTTEKTT 856

Query: 584 DGLLTSEPMGSPVSSKTESVSDKEDKP---------PLAPSGGT-----------EGPEQ 623
           +  +T+       +++  S + ++  P          LAP   T             PE+
Sbjct: 857 ESKITA------TTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEE 910

Query: 624 PPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP- 682
              P    T S          K   P  ++  K+   P + +   T P +   K+T TP 
Sbjct: 911 TAKPKDRATNS----------KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPR 960

Query: 683 --TSPGPRTHSTPSI 695
             TS  P  + T  I
Sbjct: 961 KMTSTMPELNPTSRI 975



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 102/472 (21%), Positives = 144/472 (30%), Gaps = 60/472 (12%)

Query: 589  SEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEG 648
            S P  S  S +T    +KE       +  T           + +      + K   KD  
Sbjct: 170  SLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLA 229

Query: 649  PVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSP 708
            P ++ + K T  P A E     P L+  K   TPT+P     +TP  P          +P
Sbjct: 230  PTSKVLAKPT--PKA-ETTTKGPALTTPKEP-TPTTPKEPASTTPKEP----------TP 275

Query: 709  QYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMM 768
              I   P     PA    +  P     + P +            P  +   +PA   P  
Sbjct: 276  TTIKSAPTTPKEPAPTTTKSAP-----TTPKE------------PAPTTTKEPAPTTPKE 318

Query: 769  QAAAAAGPPLVAATPYSSYIPYNP-QQFPGQPAMMQPMAHYPSQPVF-APMLQSNPRMLT 826
             A      P    T  +   P  P    P +PA   P    P+ P    P     P   T
Sbjct: 319  PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 378

Query: 827  SGSHPQAIVSSSTPQYPSAEQP------TPQALYATVHQSYPHHATQLHAHQPQPATTPT 880
                P      +TP+ P+   P      TP+    T     P         +P P TTP 
Sbjct: 379  KEPAP------TTPKEPAPTAPKKPAPTTPKEPAPTT----PKEPAPTTTKEPSP-TTPK 427

Query: 881  GSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFP 940
               P +  +AP+  +  A          P++    P       P+ P  P+  +P+   P
Sbjct: 428  EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP--SPTTTKEPAPTTPKEPAPTTPKKPAP 485

Query: 941  QPAAVYAIHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGP 1000
                  A    + P   T          +   T    P   AP  P+ +    P+    P
Sbjct: 486  TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTT---PKETAPTTPKKLTPTTPEKL-AP 541

Query: 1001 PQGAVPQSGVPALSASTPSPYPYIGHPQGEQPGQAPGFPGGADDRIPPLPPP 1052
                 P    P   A T    P    P  E+P  AP  P  A    P  P P
Sbjct: 542  TTPEKPAPTTPEELAPTTPEEPTPTTP--EEP--APTTPKAAAPNTPKEPAP 589


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 128/566 (22%), Positives = 197/566 (34%), Gaps = 71/566 (12%)

Query: 394 PGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRP------SGETSVPPPPAVGRMYPP 447
           P  +A     GP+  +PK   P    +  S+    P      S  T+   P        P
Sbjct: 290 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 349

Query: 448 RSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPTDVK 507
            +PK  AP       P  P   A  T+    P T+  +       +P +PK   APT   
Sbjct: 350 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPK-KPAPT--- 405

Query: 508 ELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPF 567
             + KEP  T  P+E      K P    ++      +     A  K  P++  E +    
Sbjct: 406 --TPKEPAPT-TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA---- 458

Query: 568 PPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPP 627
            P   KE      KE       EP  +P ++K+   + KE     AP+     P  P  P
Sbjct: 459 -PTTPKEPAPTTTKEPSPTTPKEP--APTTTKSAPTTTKEP----APTTTKSAPTTPKEP 511

Query: 628 CPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNK--STSTPTSP 685
            P+ T  P         K+  P   +    T         P +P  +  K  + +TP  P
Sbjct: 512 SPTTTKEP----APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 567

Query: 686 GPRT--HSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGK 743
            P T   + P+ P          +P+ ++  P     PA   P+     ++ + P +   
Sbjct: 568 APTTPKETAPTTPKKLTPT----TPEKLA--PTTPEKPAPTTPE----ELAPTTPEE--- 614

Query: 744 YRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQ 803
                    P  +   +PA   P  +AAA   P   A T      P  P+    +PA   
Sbjct: 615 ---------PTPTTPEEPAPTTP--KAAAPNTPKEPAPTTPKEPAPTTPK----EPAPTT 659

Query: 804 PMAHYPSQPV-FAPMLQSNPRMLT-SGSHPQAIVSSST--PQYPSAEQPTPQALYATVHQ 859
           P    P+ P   AP     P   T     P+ +  ++T  P   + ++P P     T   
Sbjct: 660 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTA-P 718

Query: 860 SYPHHATQLHAHQPQPATTPTGSQPQS-QHAAPSPVQHQAGQ--APHLGSGQPQQNLYHP 916
           + P         +P P TTP G+ P + +  AP+  +  A +  AP    G        P
Sbjct: 719 TTPKEPAPTTPKEPAP-TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKP 777

Query: 917 GALT--GTPPSLPPGPSAQSPQSSFP 940
              T   T P+ P  P+  +P+   P
Sbjct: 778 APTTPKETAPTTPKEPAPTTPKKPAP 803



 Score = 67.8 bits (164), Expect = 5e-11
 Identities = 124/579 (21%), Positives = 183/579 (31%), Gaps = 72/579 (12%)

Query: 419 AKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASI 478
           +K L+ P+  P  ET+   P     +  P+ P    P   +++ P+ P     PT+  S 
Sbjct: 284 SKVLAKPT--PKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEP----TPTTIKSA 333

Query: 479 PVTSSVSDPGVGSISPASPKISLAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQN 535
           P T            PA      APT  KE    +TKEP  T  P+E A    K P    
Sbjct: 334 PTTPK---------EPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKEPA--- 380

Query: 536 EQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSP 595
                                 S+P    +P P    K  P    KE       EP  +P
Sbjct: 381 -----------------PTTTKSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEP--TP 420

Query: 596 VSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG-SPPVGLIKGEDKDEGPVAEQV 654
            + K  + + KE  P          P++P P  P +   + P        K+  P   + 
Sbjct: 421 TTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 480

Query: 655 KKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYI 714
              T   +A          +   + +TP  P P T   P+    T  +    +P+     
Sbjct: 481 PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA--PTTPKEPAPTTPK--KPA 536

Query: 715 PQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAA 774
           P     PA   P+  P P +   P        A  + P + +        P   +  A  
Sbjct: 537 PTTPKEPAPTTPK-EPAPTTTKKPAPTTPKEPAP-TTPKETAPTTPKKLTPTTPEKLAPT 594

Query: 775 GPPLVAATPYSSYIPYNPQQ----FPGQPAMMQPMAHYPSQPVF-APMLQSNPRMLTSGS 829
            P   A T      P  P++     P +PA   P A  P+ P   AP     P   T   
Sbjct: 595 TPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 654

Query: 830 HPQAIVSSSTPQYPSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHA 889
                   + P  P    PT      T+ +  P    +    +  P TT   +       
Sbjct: 655 PAPTTPKETAPTTPKGTAPT------TLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKP 708

Query: 890 APSPVQHQAGQAPHLGSGQPQQNLYHPGALT--GTPPSLPPGPSAQSPQSSFPQPAAVYA 947
           AP+  +   G AP             P   T  GT P+    P+  +P+   P+  A   
Sbjct: 709 APTTPK---GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 765

Query: 948 IHHQQLPHGFTNMAHVTQAHVQTGITAAPPPHPGAPHPP 986
               + P   T+         +T  T    P P  P  P
Sbjct: 766 ---TKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKP 801



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 107/502 (21%), Positives = 162/502 (32%), Gaps = 67/502 (13%)

Query: 406 SRMSPKAQRPLRGAKTLSSPSN--RPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCP 463
           ++ +P   +      T S+P+    PS  T+  P P   +   P +PK  AP       P
Sbjct: 486 TKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP 545

Query: 464 EPPIGSAVPTSSASIPVTSSVSDPGV-GSISPASPKISLAPTDVKEL--STKEPGRTLEP 520
             P   A  T+    P T     P      +P +PK  L PT  ++L  +T E      P
Sbjct: 546 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTP 604

Query: 521 QELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFP-------PRILK 573
           +ELA    + P     ++                  +++P    +P P       P   K
Sbjct: 605 EELAPTTPEEPTPTTPEEPAP-----------TTPKAAAPNTPKEPAPTTPKEPAPTTPK 653

Query: 574 EEPKGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAPSGGTEGPEQPPPPCPSQTG 633
           E      KE      + P G+  ++  E       KP       T   E     C     
Sbjct: 654 EPAPTTPKET---APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAP 710

Query: 634 SPPVGLIKGEDKDEGPV-----AEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTPTSPGPR 688
           + P G      K+  P      A    K T     KE  PT P     K  +  T+ GP 
Sbjct: 711 TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP- 769

Query: 689 THSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAK 748
           T +T   P  T  +            P     PA   P+  P P +   P          
Sbjct: 770 TSTTSDKPAPTTPK---------ETAPTTPKEPAPTTPKK-PAPTTPETP---------- 809

Query: 749 GSLPPQRSDQHQPASA--PPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMA 806
              PP  S+   P +   P  +  +     P ++A P    +  +P++ PG P    P A
Sbjct: 810 ---PPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKE-PGVPTTKTPAA 865

Query: 807 HYPSQPVFAP------MLQSNPRMLTSGSHPQAIVSSSTPQYPSAE--QPTPQALYATVH 858
             P     A        L++ P   T+        +++T +   ++    T Q    T  
Sbjct: 866 TKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQ 925

Query: 859 QSYPHHATQLHAHQPQPATTPT 880
            + P   T L      P  T T
Sbjct: 926 DTTPFKITTLKTTTLAPKVTTT 947



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 113/544 (20%), Positives = 176/544 (32%), Gaps = 67/544 (12%)

Query: 381 PRGPHHLDNSSPGPGSEARGINGGPSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPA 440
           P+ P       P P +        P   +P  + P        +P+       + P  PA
Sbjct: 399 PKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 458

Query: 441 VGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKIS 500
                 P    +  P+P +   P        PT++ S P T+    P     +P +PK  
Sbjct: 459 PTTPKEPAPTTTKEPSPTTPKEP-------APTTTKSAPTTTKEPAPTTTKSAPTTPK-E 510

Query: 501 LAPTDVKE---LSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPS 557
            +PT  KE    + KEP  T  P++ A    K P     ++       +      K    
Sbjct: 511 PSPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 569

Query: 558 SSPENSLDPFPPRILKEEPK---GKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPLAP 614
           ++P+ +    P ++    P+       E     T E +      +    + +E  P    
Sbjct: 570 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPK 629

Query: 615 SGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGP--VAEQVKKSTLNPNAKEFNPTKPL 672
           +     P++P P  P +    P      E     P   A    K T     KE  PT P 
Sbjct: 630 AAAPNTPKEPAPTTPKE----PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPK 685

Query: 673 LSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYPYP 732
               K  +  T+  P T +T   P                  P    G A   P+  P P
Sbjct: 686 KPAPKELAPTTTKEP-TSTTCDKPA-----------------PTTPKGTAPTTPK-EPAP 726

Query: 733 VSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLV---AATPYSSYIP 789
            +   P         KG+ P   +   +PA   P   A     P       +T      P
Sbjct: 727 TTPKEPAP----TTPKGTAP---TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 779

Query: 790 YNPQQ----FPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSS---STPQY 842
             P++     P +PA   P    P+ P   P   S     T+   P  I  S   STP+ 
Sbjct: 780 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 839

Query: 843 PSAEQPTPQALYATVHQSYPHHATQLHAHQPQPATTPTG--------SQPQSQHAAPSPV 894
             + +PTP+AL  +  +          A +P+  TT           + P++  AAP   
Sbjct: 840 --SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 897

Query: 895 QHQA 898
           +  A
Sbjct: 898 KETA 901



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 73/315 (23%), Positives = 110/315 (34%), Gaps = 59/315 (18%)

Query: 405  PSRMSPKAQRPLRGAKTLSSPSNRPSGETSVPPPPAVGRMYPPRSPKSAAPAPISASCPE 464
            P+  +PK   P   A T +     P+  TS  P P   +   P +PK  AP       P 
Sbjct: 748  PAPTTPKKPAPKELAPTTTKG---PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPT 804

Query: 465  PPIGSAVPTSSASIPVTSSVSDPGVGSISPASPKISLAPT-DVKELSTKEPGRTLEPQEL 523
             P      TS  S P T+        S   ++P++S  PT    E S KEPG    P   
Sbjct: 805  TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPG---VPTTK 861

Query: 524  ARIAGKVPGLQNEQKRFQLEELRKFGAQFKLQPSSSPENSLDPFPPRILKEEPKGKEKEV 583
               A K       + +    +LR           ++PE +     P++ KE     EK  
Sbjct: 862  TPAATKPEMTTTAKDKTTERDLR-----------TTPETT--TAAPKMTKETATTTEKTT 908

Query: 584  DGLLTSEPMGSPVSSKTESVSDKEDKP---------PLAPSGGT-----------EGPEQ 623
            +  +T+       +++  S + ++  P          LAP   T             PE+
Sbjct: 909  ESKITA------TTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEE 962

Query: 624  PPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSVNKSTSTP- 682
               P    T S          K   P  ++  K+   P + +   T P +   K+T TP 
Sbjct: 963  TAKPKDRATNS----------KATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPR 1012

Query: 683  --TSPGPRTHSTPSI 695
              TS  P  + T  I
Sbjct: 1013 KMTSTMPELNPTSRI 1027



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 132/636 (20%), Positives = 202/636 (31%), Gaps = 74/636 (11%)

Query: 432  ETSVPPPPAVGRMYPPRSPKSAAPAPISASCPEPPIGSAVPTSSASIPVTSSVSDPGVGS 491
            E   P  P   +  PP S  S      +   P+PP          S  +T   S      
Sbjct: 65   EVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQE 124

Query: 492  ISPASPKISLAPTDVKELSTKEPGRTLEPQELARIAGKVPGLQNEQKRFQLEELRKFGA- 550
             S +S   S + T  K  S+K      E Q+  ++         ++   +   + + G+ 
Sbjct: 125  SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSG 184

Query: 551  ----QFKLQP--SSSPENSLDPFPPRILKEEPKGKEKEVDGLLTSEPMGSPVSSKTESVS 604
                 FK+    +S+ +++     P+I   +P      +     +    S   +K  +V 
Sbjct: 185  LDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVE 244

Query: 605  DKEDKPPLAPSGGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAK 664
             KE       +  T+G E+      +Q+      + K   KD  P ++ + K T  P A 
Sbjct: 245  TKETTTTNKQTS-TDGKEKTTSAKETQS------IEKTSAKDLAPTSKVLAKPT--PKA- 294

Query: 665  EFNPTKPLLSVNKSTSTPTSPGPRTHSTPSIPVLTAGQSGLYSPQYISYIPQIHMGPAVQ 724
            E     P L+  K   TPT+P     +TP  P          +P  I   P     PA  
Sbjct: 295  ETTTKGPALTTPKEP-TPTTPKEPASTTPKEP----------TPTTIKSAPTTPKEPAPT 343

Query: 725  APQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPPMMQAAAAAGPPLVAATPY 784
              +  P     + P +            P  +   +PA   P   A      P    T  
Sbjct: 344  TTKSAP-----TTPKE------------PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS 386

Query: 785  SSYIPYNP-QQFPGQPAMMQPMAHYPSQPVF-APMLQSNPRMLTSGSHPQAIVSSSTPQY 842
            +   P  P    P +PA   P    P+ P    P     P   T    P      +TP+ 
Sbjct: 387  APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP------TTPKE 440

Query: 843  PSAEQP------TPQALYATVHQSYPHHATQLHAHQPQPATTPTGSQPQSQHAAPSPVQH 896
            P+   P      TP+    T     P         +P P TTP    P +  +AP+  + 
Sbjct: 441  PAPTAPKKPAPTTPKEPAPTT----PKEPAPTTTKEPSP-TTPKEPAPTTTKSAPTTTKE 495

Query: 897  QAGQAPHLGSGQPQQNLYHPGALTGTPPSLPPGPSAQSPQSSFPQPAAVYAIHHQQLPHG 956
             A          P++    P       P+ P  P+  +P+   P      A    + P  
Sbjct: 496  PAPTTTKSAPTTPKEP--SPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP 553

Query: 957  FTNMAHVTQAHVQTGITAAPPPHPGAPHPPQVMLLHPPQSHGGPPQGAVPQSGVPALSAS 1016
             T          +   T    P   AP  P+ +    P+    P     P    P   A 
Sbjct: 554  TTTKKPAPTTPKEPAPTT---PKETAPTTPKKLTPTTPEKL-APTTPEKPAPTTPEELAP 609

Query: 1017 TPSPYPYIGHPQGEQPGQAPGFPGGADDRIPPLPPP 1052
            T    P    P  E+P  AP  P  A    P  P P
Sbjct: 610  TTPEEPTPTTP--EEP--APTTPKAAAPNTPKEPAP 641


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.129    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,046,888
Number of Sequences: 37866
Number of extensions: 4579583
Number of successful extensions: 52882
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 371
Number of HSP's successfully gapped in prelim test: 2409
Number of HSP's that attempted gapping in prelim test: 22958
Number of HSP's gapped (non-prelim): 22492
length of query: 1062
length of database: 18,247,518
effective HSP length: 113
effective length of query: 949
effective length of database: 13,968,660
effective search space: 13256258340
effective search space used: 13256258340
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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