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Search of human proteins with 26051227
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|26051227 sperm-associated cation channel 2 isoform 4 [Homo
sapiens]
(199 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|26051227 sperm-associated cation channel 2 isoform 4 [Homo sa... 394 e-110
gi|26051223 sperm-associated cation channel 2 isoform 2 [Homo sa... 374 e-104
gi|16876443 sperm-associated cation channel 2 isoform 1 [Homo sa... 374 e-104
gi|93141214 sodium channel, voltage-gated, type II, alpha isofor... 49 2e-06
gi|93141212 sodium channel, voltage-gated, type II, alpha isofor... 49 2e-06
gi|93141210 sodium channel, voltage-gated, type II, alpha isofor... 49 2e-06
gi|237512982 voltage-gated sodium channel type V alpha isoform f... 49 3e-06
gi|237512980 voltage-gated sodium channel type V alpha isoform e... 49 3e-06
gi|37622907 voltage-gated sodium channel type V alpha isoform a ... 49 3e-06
gi|30089970 voltage-gated sodium channel type V alpha isoform b ... 49 3e-06
gi|150417969 voltage-gated sodium channel type V alpha isoform d... 49 3e-06
gi|150417967 voltage-gated sodium channel type V alpha isoform c... 49 3e-06
gi|126362955 sodium channel, voltage-gated, type III, alpha isof... 48 6e-06
gi|126362947 sodium channel, voltage-gated, type III, alpha isof... 48 6e-06
gi|126362949 sodium channel, voltage-gated, type III, alpha isof... 48 6e-06
gi|62988334 cation channel, sperm associated 4 [Homo sapiens] 48 6e-06
gi|7657544 sodium channel, voltage gated, type VIII, alpha [Homo... 47 1e-05
gi|111378393 sodium channel, voltage-gated, type VII, alpha [Hom... 47 1e-05
gi|4506813 sodium channel, voltage-gated, type IX, alpha [Homo s... 47 1e-05
gi|110349767 calcium channel, voltage-dependent, L type, alpha 1... 46 2e-05
gi|93587342 voltage-gated sodium channel type 4 alpha [Homo sapi... 45 3e-05
gi|115583677 sodium channel, voltage-gated, type I, alpha [Homo ... 45 3e-05
gi|110835710 sodium channel, voltage-gated, type X, alpha [Homo ... 44 7e-05
gi|115583667 sodium channel, voltage-gated, type XI, alpha [Homo... 44 9e-05
gi|239748090 PREDICTED: similar to sodium channel, voltage-gated... 41 8e-04
gi|53832005 calcium channel, voltage-dependent, R type, alpha 1E... 39 0.002
gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B ... 39 0.004
gi|20070163 voltage-dependent calcium channel alpha 1G subunit i... 37 0.008
gi|38505294 voltage-dependent calcium channel alpha 1G subunit i... 37 0.008
gi|38505292 voltage-dependent calcium channel alpha 1G subunit i... 37 0.008
>gi|26051227 sperm-associated cation channel 2 isoform 4 [Homo
sapiens]
Length = 199
Score = 394 bits (1013), Expect = e-110
Identities = 199/199 (100%), Positives = 199/199 (100%)
Query: 1 MAAYQQEEQMQLPRADAIRSRLIDTFSLIEHLQGLSQAVPRHTIRELLDPSRQKKLVLGD 60
MAAYQQEEQMQLPRADAIRSRLIDTFSLIEHLQGLSQAVPRHTIRELLDPSRQKKLVLGD
Sbjct: 1 MAAYQQEEQMQLPRADAIRSRLIDTFSLIEHLQGLSQAVPRHTIRELLDPSRQKKLVLGD 60
Query: 61 QHQLVRFSIKPQRIEQISHAQRLLSRLHVRCSQRPPLSLWAGWVLECPLFKNFIIFLVFL 120
QHQLVRFSIKPQRIEQISHAQRLLSRLHVRCSQRPPLSLWAGWVLECPLFKNFIIFLVFL
Sbjct: 61 QHQLVRFSIKPQRIEQISHAQRLLSRLHVRCSQRPPLSLWAGWVLECPLFKNFIIFLVFL 120
Query: 121 NTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILLKWLSNFSVFWKSAWNVF 180
NTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILLKWLSNFSVFWKSAWNVF
Sbjct: 121 NTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILLKWLSNFSVFWKSAWNVF 180
Query: 181 DFVVTMLVRIEILRVRLVG 199
DFVVTMLVRIEILRVRLVG
Sbjct: 181 DFVVTMLVRIEILRVRLVG 199
>gi|26051223 sperm-associated cation channel 2 isoform 2 [Homo
sapiens]
Length = 530
Score = 374 bits (959), Expect = e-104
Identities = 187/187 (100%), Positives = 187/187 (100%)
Query: 1 MAAYQQEEQMQLPRADAIRSRLIDTFSLIEHLQGLSQAVPRHTIRELLDPSRQKKLVLGD 60
MAAYQQEEQMQLPRADAIRSRLIDTFSLIEHLQGLSQAVPRHTIRELLDPSRQKKLVLGD
Sbjct: 1 MAAYQQEEQMQLPRADAIRSRLIDTFSLIEHLQGLSQAVPRHTIRELLDPSRQKKLVLGD 60
Query: 61 QHQLVRFSIKPQRIEQISHAQRLLSRLHVRCSQRPPLSLWAGWVLECPLFKNFIIFLVFL 120
QHQLVRFSIKPQRIEQISHAQRLLSRLHVRCSQRPPLSLWAGWVLECPLFKNFIIFLVFL
Sbjct: 61 QHQLVRFSIKPQRIEQISHAQRLLSRLHVRCSQRPPLSLWAGWVLECPLFKNFIIFLVFL 120
Query: 121 NTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILLKWLSNFSVFWKSAWNVF 180
NTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILLKWLSNFSVFWKSAWNVF
Sbjct: 121 NTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILLKWLSNFSVFWKSAWNVF 180
Query: 181 DFVVTML 187
DFVVTML
Sbjct: 181 DFVVTML 187
>gi|16876443 sperm-associated cation channel 2 isoform 1 [Homo
sapiens]
Length = 528
Score = 374 bits (959), Expect = e-104
Identities = 187/187 (100%), Positives = 187/187 (100%)
Query: 1 MAAYQQEEQMQLPRADAIRSRLIDTFSLIEHLQGLSQAVPRHTIRELLDPSRQKKLVLGD 60
MAAYQQEEQMQLPRADAIRSRLIDTFSLIEHLQGLSQAVPRHTIRELLDPSRQKKLVLGD
Sbjct: 1 MAAYQQEEQMQLPRADAIRSRLIDTFSLIEHLQGLSQAVPRHTIRELLDPSRQKKLVLGD 60
Query: 61 QHQLVRFSIKPQRIEQISHAQRLLSRLHVRCSQRPPLSLWAGWVLECPLFKNFIIFLVFL 120
QHQLVRFSIKPQRIEQISHAQRLLSRLHVRCSQRPPLSLWAGWVLECPLFKNFIIFLVFL
Sbjct: 61 QHQLVRFSIKPQRIEQISHAQRLLSRLHVRCSQRPPLSLWAGWVLECPLFKNFIIFLVFL 120
Query: 121 NTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILLKWLSNFSVFWKSAWNVF 180
NTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILLKWLSNFSVFWKSAWNVF
Sbjct: 121 NTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILLKWLSNFSVFWKSAWNVF 180
Query: 181 DFVVTML 187
DFVVTML
Sbjct: 181 DFVVTML 187
>gi|93141214 sodium channel, voltage-gated, type II, alpha isoform 2
[Homo sapiens]
Length = 2005
Score = 49.3 bits (116), Expect = 2e-06
Identities = 29/82 (35%), Positives = 47/82 (57%), Gaps = 5/82 (6%)
Query: 104 VLECPLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILL 163
++E F+ FI+F++ L++ L E +E T +K LE A IFILE+LL
Sbjct: 1204 IVEHNWFETFIVFMILLSSGALAFEDIYIEQRKT----IKTMLEYADKVFTYIFILEMLL 1259
Query: 164 KWLS-NFSVFWKSAWNVFDFVV 184
KW++ F V++ +AW DF++
Sbjct: 1260 KWVAYGFQVYFTNAWCWLDFLI 1281
Score = 39.7 bits (91), Expect = 0.002
Identities = 35/123 (28%), Positives = 59/123 (47%), Gaps = 16/123 (13%)
Query: 84 LSRLHVRCSQRP---PLSLWAGWVLEC---PLFKNFIIFLVFLNTIILMVEIE--LLEST 135
+ +L + Q+P P + + G V + +F I+ L+ LN + +MVE + E T
Sbjct: 1501 MKKLGSKKPQKPIPRPANKFQGMVFDFVTKQVFDISIMILICLNMVTMMVETDDQSQEMT 1560
Query: 136 NTKLWPLKLTLEVAAWFILLIFILEILLKWLSNFSVFWKSAWNVFDFVVTMLVRIEILRV 195
N W + FI+L F E +LK +S ++ WN+FDFVV +L + +
Sbjct: 1561 NILYW-------INLVFIVL-FTGECVLKLISLRYYYFTIGWNIFDFVVVILSIVGMFLA 1612
Query: 196 RLV 198
L+
Sbjct: 1613 ELI 1615
>gi|93141212 sodium channel, voltage-gated, type II, alpha isoform 1
[Homo sapiens]
Length = 2005
Score = 49.3 bits (116), Expect = 2e-06
Identities = 29/82 (35%), Positives = 47/82 (57%), Gaps = 5/82 (6%)
Query: 104 VLECPLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILL 163
++E F+ FI+F++ L++ L E +E T +K LE A IFILE+LL
Sbjct: 1204 IVEHNWFETFIVFMILLSSGALAFEDIYIEQRKT----IKTMLEYADKVFTYIFILEMLL 1259
Query: 164 KWLS-NFSVFWKSAWNVFDFVV 184
KW++ F V++ +AW DF++
Sbjct: 1260 KWVAYGFQVYFTNAWCWLDFLI 1281
Score = 39.7 bits (91), Expect = 0.002
Identities = 35/123 (28%), Positives = 59/123 (47%), Gaps = 16/123 (13%)
Query: 84 LSRLHVRCSQRP---PLSLWAGWVLEC---PLFKNFIIFLVFLNTIILMVEIE--LLEST 135
+ +L + Q+P P + + G V + +F I+ L+ LN + +MVE + E T
Sbjct: 1501 MKKLGSKKPQKPIPRPANKFQGMVFDFVTKQVFDISIMILICLNMVTMMVETDDQSQEMT 1560
Query: 136 NTKLWPLKLTLEVAAWFILLIFILEILLKWLSNFSVFWKSAWNVFDFVVTMLVRIEILRV 195
N W + FI+L F E +LK +S ++ WN+FDFVV +L + +
Sbjct: 1561 NILYW-------INLVFIVL-FTGECVLKLISLRYYYFTIGWNIFDFVVVILSIVGMFLA 1612
Query: 196 RLV 198
L+
Sbjct: 1613 ELI 1615
>gi|93141210 sodium channel, voltage-gated, type II, alpha isoform 1
[Homo sapiens]
Length = 2005
Score = 49.3 bits (116), Expect = 2e-06
Identities = 29/82 (35%), Positives = 47/82 (57%), Gaps = 5/82 (6%)
Query: 104 VLECPLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILL 163
++E F+ FI+F++ L++ L E +E T +K LE A IFILE+LL
Sbjct: 1204 IVEHNWFETFIVFMILLSSGALAFEDIYIEQRKT----IKTMLEYADKVFTYIFILEMLL 1259
Query: 164 KWLS-NFSVFWKSAWNVFDFVV 184
KW++ F V++ +AW DF++
Sbjct: 1260 KWVAYGFQVYFTNAWCWLDFLI 1281
Score = 39.7 bits (91), Expect = 0.002
Identities = 35/123 (28%), Positives = 59/123 (47%), Gaps = 16/123 (13%)
Query: 84 LSRLHVRCSQRP---PLSLWAGWVLEC---PLFKNFIIFLVFLNTIILMVEIE--LLEST 135
+ +L + Q+P P + + G V + +F I+ L+ LN + +MVE + E T
Sbjct: 1501 MKKLGSKKPQKPIPRPANKFQGMVFDFVTKQVFDISIMILICLNMVTMMVETDDQSQEMT 1560
Query: 136 NTKLWPLKLTLEVAAWFILLIFILEILLKWLSNFSVFWKSAWNVFDFVVTMLVRIEILRV 195
N W + FI+L F E +LK +S ++ WN+FDFVV +L + +
Sbjct: 1561 NILYW-------INLVFIVL-FTGECVLKLISLRYYYFTIGWNIFDFVVVILSIVGMFLA 1612
Query: 196 RLV 198
L+
Sbjct: 1613 ELI 1615
>gi|237512982 voltage-gated sodium channel type V alpha isoform f
[Homo sapiens]
Length = 1962
Score = 48.9 bits (115), Expect = 3e-06
Identities = 28/82 (34%), Positives = 47/82 (57%), Gaps = 5/82 (6%)
Query: 104 VLECPLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILL 163
++E F+ FIIF++ L++ L E LE T +K+ LE A +F+LE+LL
Sbjct: 1147 IVEHSWFETFIIFMILLSSGALAFEDIYLEERKT----IKVLLEYADKMFTYVFVLEMLL 1202
Query: 164 KWLS-NFSVFWKSAWNVFDFVV 184
KW++ F ++ +AW DF++
Sbjct: 1203 KWVAYGFKKYFTNAWCWLDFLI 1224
Score = 40.8 bits (94), Expect = 8e-04
Identities = 36/147 (24%), Positives = 72/147 (48%), Gaps = 20/147 (13%)
Query: 47 LLDPSRQKKLVLGDQHQLVRFSIKPQRIEQISHAQRLLSRLHVRCSQRP---PLSLWAGW 103
++D Q+K LG Q + E+ + +L + Q+P PL+ + G+
Sbjct: 1415 IIDNFNQQKKKLGGQDIFMT--------EEQKKYYNAMKKLGSKKPQKPIPRPLNKYQGF 1466
Query: 104 VLECPLFKNF---IIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILE 160
+ + + F I+FL+ LN + +MVE + + + K+ + ++ F+ IF E
Sbjct: 1467 IFDIVTKQAFDVTIMFLICLNMVTMMVETD--DQSPEKI---NILAKINLLFVA-IFTGE 1520
Query: 161 ILLKWLSNFSVFWKSAWNVFDFVVTML 187
++K + ++ ++WN+FDFVV +L
Sbjct: 1521 CIVKLAALRHYYFTNSWNIFDFVVVIL 1547
>gi|237512980 voltage-gated sodium channel type V alpha isoform e
[Homo sapiens]
Length = 1983
Score = 48.9 bits (115), Expect = 3e-06
Identities = 28/82 (34%), Positives = 47/82 (57%), Gaps = 5/82 (6%)
Query: 104 VLECPLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILL 163
++E F+ FIIF++ L++ L E LE T +K+ LE A +F+LE+LL
Sbjct: 1200 IVEHSWFETFIIFMILLSSGALAFEDIYLEERKT----IKVLLEYADKMFTYVFVLEMLL 1255
Query: 164 KWLS-NFSVFWKSAWNVFDFVV 184
KW++ F ++ +AW DF++
Sbjct: 1256 KWVAYGFKKYFTNAWCWLDFLI 1277
>gi|37622907 voltage-gated sodium channel type V alpha isoform a [Homo
sapiens]
Length = 2016
Score = 48.9 bits (115), Expect = 3e-06
Identities = 28/82 (34%), Positives = 47/82 (57%), Gaps = 5/82 (6%)
Query: 104 VLECPLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILL 163
++E F+ FIIF++ L++ L E LE T +K+ LE A +F+LE+LL
Sbjct: 1201 IVEHSWFETFIIFMILLSSGALAFEDIYLEERKT----IKVLLEYADKMFTYVFVLEMLL 1256
Query: 164 KWLS-NFSVFWKSAWNVFDFVV 184
KW++ F ++ +AW DF++
Sbjct: 1257 KWVAYGFKKYFTNAWCWLDFLI 1278
Score = 40.8 bits (94), Expect = 8e-04
Identities = 36/147 (24%), Positives = 72/147 (48%), Gaps = 20/147 (13%)
Query: 47 LLDPSRQKKLVLGDQHQLVRFSIKPQRIEQISHAQRLLSRLHVRCSQRP---PLSLWAGW 103
++D Q+K LG Q + E+ + +L + Q+P PL+ + G+
Sbjct: 1469 IIDNFNQQKKKLGGQDIFMT--------EEQKKYYNAMKKLGSKKPQKPIPRPLNKYQGF 1520
Query: 104 VLECPLFKNF---IIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILE 160
+ + + F I+FL+ LN + +MVE + + + K+ + ++ F+ IF E
Sbjct: 1521 IFDIVTKQAFDVTIMFLICLNMVTMMVETD--DQSPEKI---NILAKINLLFVA-IFTGE 1574
Query: 161 ILLKWLSNFSVFWKSAWNVFDFVVTML 187
++K + ++ ++WN+FDFVV +L
Sbjct: 1575 CIVKLAALRHYYFTNSWNIFDFVVVIL 1601
>gi|30089970 voltage-gated sodium channel type V alpha isoform b [Homo
sapiens]
Length = 2015
Score = 48.9 bits (115), Expect = 3e-06
Identities = 28/82 (34%), Positives = 47/82 (57%), Gaps = 5/82 (6%)
Query: 104 VLECPLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILL 163
++E F+ FIIF++ L++ L E LE T +K+ LE A +F+LE+LL
Sbjct: 1200 IVEHSWFETFIIFMILLSSGALAFEDIYLEERKT----IKVLLEYADKMFTYVFVLEMLL 1255
Query: 164 KWLS-NFSVFWKSAWNVFDFVV 184
KW++ F ++ +AW DF++
Sbjct: 1256 KWVAYGFKKYFTNAWCWLDFLI 1277
Score = 40.8 bits (94), Expect = 8e-04
Identities = 36/147 (24%), Positives = 72/147 (48%), Gaps = 20/147 (13%)
Query: 47 LLDPSRQKKLVLGDQHQLVRFSIKPQRIEQISHAQRLLSRLHVRCSQRP---PLSLWAGW 103
++D Q+K LG Q + E+ + +L + Q+P PL+ + G+
Sbjct: 1468 IIDNFNQQKKKLGGQDIFMT--------EEQKKYYNAMKKLGSKKPQKPIPRPLNKYQGF 1519
Query: 104 VLECPLFKNF---IIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILE 160
+ + + F I+FL+ LN + +MVE + + + K+ + ++ F+ IF E
Sbjct: 1520 IFDIVTKQAFDVTIMFLICLNMVTMMVETD--DQSPEKI---NILAKINLLFVA-IFTGE 1573
Query: 161 ILLKWLSNFSVFWKSAWNVFDFVVTML 187
++K + ++ ++WN+FDFVV +L
Sbjct: 1574 CIVKLAALRHYYFTNSWNIFDFVVVIL 1600
>gi|150417969 voltage-gated sodium channel type V alpha isoform d
[Homo sapiens]
Length = 1998
Score = 48.9 bits (115), Expect = 3e-06
Identities = 28/82 (34%), Positives = 47/82 (57%), Gaps = 5/82 (6%)
Query: 104 VLECPLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILL 163
++E F+ FIIF++ L++ L E LE T +K+ LE A +F+LE+LL
Sbjct: 1201 IVEHSWFETFIIFMILLSSGALAFEDIYLEERKT----IKVLLEYADKMFTYVFVLEMLL 1256
Query: 164 KWLS-NFSVFWKSAWNVFDFVV 184
KW++ F ++ +AW DF++
Sbjct: 1257 KWVAYGFKKYFTNAWCWLDFLI 1278
Score = 40.8 bits (94), Expect = 8e-04
Identities = 36/147 (24%), Positives = 72/147 (48%), Gaps = 20/147 (13%)
Query: 47 LLDPSRQKKLVLGDQHQLVRFSIKPQRIEQISHAQRLLSRLHVRCSQRP---PLSLWAGW 103
++D Q+K LG Q + E+ + +L + Q+P PL+ + G+
Sbjct: 1451 IIDNFNQQKKKLGGQDIFMT--------EEQKKYYNAMKKLGSKKPQKPIPRPLNKYQGF 1502
Query: 104 VLECPLFKNF---IIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILE 160
+ + + F I+FL+ LN + +MVE + + + K+ + ++ F+ IF E
Sbjct: 1503 IFDIVTKQAFDVTIMFLICLNMVTMMVETD--DQSPEKI---NILAKINLLFVA-IFTGE 1556
Query: 161 ILLKWLSNFSVFWKSAWNVFDFVVTML 187
++K + ++ ++WN+FDFVV +L
Sbjct: 1557 CIVKLAALRHYYFTNSWNIFDFVVVIL 1583
>gi|150417967 voltage-gated sodium channel type V alpha isoform c
[Homo sapiens]
Length = 2016
Score = 48.9 bits (115), Expect = 3e-06
Identities = 28/82 (34%), Positives = 47/82 (57%), Gaps = 5/82 (6%)
Query: 104 VLECPLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILL 163
++E F+ FIIF++ L++ L E LE T +K+ LE A +F+LE+LL
Sbjct: 1201 IVEHSWFETFIIFMILLSSGALAFEDIYLEERKT----IKVLLEYADKMFTYVFVLEMLL 1256
Query: 164 KWLS-NFSVFWKSAWNVFDFVV 184
KW++ F ++ +AW DF++
Sbjct: 1257 KWVAYGFKKYFTNAWCWLDFLI 1278
Score = 40.8 bits (94), Expect = 8e-04
Identities = 36/147 (24%), Positives = 72/147 (48%), Gaps = 20/147 (13%)
Query: 47 LLDPSRQKKLVLGDQHQLVRFSIKPQRIEQISHAQRLLSRLHVRCSQRP---PLSLWAGW 103
++D Q+K LG Q + E+ + +L + Q+P PL+ + G+
Sbjct: 1469 IIDNFNQQKKKLGGQDIFMT--------EEQKKYYNAMKKLGSKKPQKPIPRPLNKYQGF 1520
Query: 104 VLECPLFKNF---IIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILE 160
+ + + F I+FL+ LN + +MVE + + + K+ + ++ F+ IF E
Sbjct: 1521 IFDIVTKQAFDVTIMFLICLNMVTMMVETD--DQSPEKI---NILAKINLLFVA-IFTGE 1574
Query: 161 ILLKWLSNFSVFWKSAWNVFDFVVTML 187
++K + ++ ++WN+FDFVV +L
Sbjct: 1575 CIVKLAALRHYYFTNSWNIFDFVVVIL 1601
>gi|126362955 sodium channel, voltage-gated, type III, alpha isoform 3
[Homo sapiens]
Length = 1951
Score = 47.8 bits (112), Expect = 6e-06
Identities = 28/82 (34%), Positives = 46/82 (56%), Gaps = 5/82 (6%)
Query: 104 VLECPLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILL 163
++E F+ FI+F++ L++ L E +E T +K LE A IFILE+LL
Sbjct: 1153 IVEHNWFETFIVFMILLSSGALAFEDIYIEQRKT----IKTMLEYADKVFTYIFILEMLL 1208
Query: 164 KWLS-NFSVFWKSAWNVFDFVV 184
KW++ F ++ +AW DF++
Sbjct: 1209 KWVAYGFQTYFTNAWCWLDFLI 1230
Score = 37.7 bits (86), Expect = 0.006
Identities = 30/110 (27%), Positives = 54/110 (49%), Gaps = 12/110 (10%)
Query: 84 LSRLHVRCSQRP---PLSLWAGWVLEC---PLFKNFIIFLVFLNTIILMVEIELLESTNT 137
+ +L + Q+P P + + G V + +F I+ L+ LN + +MVE T+
Sbjct: 1447 MKKLGSKKPQKPIPRPANKFQGMVFDFVTRQVFDISIMILICLNMVTMMVE------TDD 1500
Query: 138 KLWPLKLTLEVAAWFILLIFILEILLKWLSNFSVFWKSAWNVFDFVVTML 187
+ + L L +++F E +LK +S ++ WN+FDFVV +L
Sbjct: 1501 QGKYMTLVLSRINLVFIVLFTGEFVLKLVSLRHYYFTIGWNIFDFVVVIL 1550
>gi|126362947 sodium channel, voltage-gated, type III, alpha isoform 2
[Homo sapiens]
Length = 1951
Score = 47.8 bits (112), Expect = 6e-06
Identities = 28/82 (34%), Positives = 46/82 (56%), Gaps = 5/82 (6%)
Query: 104 VLECPLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILL 163
++E F+ FI+F++ L++ L E +E T +K LE A IFILE+LL
Sbjct: 1153 IVEHNWFETFIVFMILLSSGALAFEDIYIEQRKT----IKTMLEYADKVFTYIFILEMLL 1208
Query: 164 KWLS-NFSVFWKSAWNVFDFVV 184
KW++ F ++ +AW DF++
Sbjct: 1209 KWVAYGFQTYFTNAWCWLDFLI 1230
Score = 37.7 bits (86), Expect = 0.006
Identities = 30/110 (27%), Positives = 54/110 (49%), Gaps = 12/110 (10%)
Query: 84 LSRLHVRCSQRP---PLSLWAGWVLEC---PLFKNFIIFLVFLNTIILMVEIELLESTNT 137
+ +L + Q+P P + + G V + +F I+ L+ LN + +MVE T+
Sbjct: 1447 MKKLGSKKPQKPIPRPANKFQGMVFDFVTRQVFDISIMILICLNMVTMMVE------TDD 1500
Query: 138 KLWPLKLTLEVAAWFILLIFILEILLKWLSNFSVFWKSAWNVFDFVVTML 187
+ + L L +++F E +LK +S ++ WN+FDFVV +L
Sbjct: 1501 QGKYMTLVLSRINLVFIVLFTGEFVLKLVSLRHYYFTIGWNIFDFVVVIL 1550
>gi|126362949 sodium channel, voltage-gated, type III, alpha isoform 1
[Homo sapiens]
Length = 2000
Score = 47.8 bits (112), Expect = 6e-06
Identities = 28/82 (34%), Positives = 46/82 (56%), Gaps = 5/82 (6%)
Query: 104 VLECPLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILL 163
++E F+ FI+F++ L++ L E +E T +K LE A IFILE+LL
Sbjct: 1202 IVEHNWFETFIVFMILLSSGALAFEDIYIEQRKT----IKTMLEYADKVFTYIFILEMLL 1257
Query: 164 KWLS-NFSVFWKSAWNVFDFVV 184
KW++ F ++ +AW DF++
Sbjct: 1258 KWVAYGFQTYFTNAWCWLDFLI 1279
Score = 37.7 bits (86), Expect = 0.006
Identities = 30/110 (27%), Positives = 54/110 (49%), Gaps = 12/110 (10%)
Query: 84 LSRLHVRCSQRP---PLSLWAGWVLEC---PLFKNFIIFLVFLNTIILMVEIELLESTNT 137
+ +L + Q+P P + + G V + +F I+ L+ LN + +MVE T+
Sbjct: 1496 MKKLGSKKPQKPIPRPANKFQGMVFDFVTRQVFDISIMILICLNMVTMMVE------TDD 1549
Query: 138 KLWPLKLTLEVAAWFILLIFILEILLKWLSNFSVFWKSAWNVFDFVVTML 187
+ + L L +++F E +LK +S ++ WN+FDFVV +L
Sbjct: 1550 QGKYMTLVLSRINLVFIVLFTGEFVLKLVSLRHYYFTIGWNIFDFVVVIL 1599
>gi|62988334 cation channel, sperm associated 4 [Homo sapiens]
Length = 472
Score = 47.8 bits (112), Expect = 6e-06
Identities = 23/85 (27%), Positives = 45/85 (52%), Gaps = 5/85 (5%)
Query: 104 VLECPLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILL 163
+L P F+ + L+ +N I + + + K + L T++ +L I + E+LL
Sbjct: 88 LLRHPAFQLLLALLLVINAITIALRTN--SYLDQKHYELFSTIDD---IVLTILLCEVLL 142
Query: 164 KWLSNFSVFWKSAWNVFDFVVTMLV 188
WL+ F +FWK WN+ +F++ ++
Sbjct: 143 GWLNGFWIFWKDGWNILNFIIVFIL 167
>gi|7657544 sodium channel, voltage gated, type VIII, alpha [Homo
sapiens]
Length = 1980
Score = 47.0 bits (110), Expect = 1e-05
Identities = 29/91 (31%), Positives = 49/91 (53%), Gaps = 5/91 (5%)
Query: 104 VLECPLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILL 163
++E F+ FIIF++ L++ L E +E T ++ LE A IFILE+LL
Sbjct: 1194 IVEHNWFETFIIFMILLSSGALAFEDIYIEQRKT----IRTILEYADKVFTYIFILEMLL 1249
Query: 164 KWLS-NFSVFWKSAWNVFDFVVTMLVRIEIL 193
KW + F F+ +AW DF++ + + ++
Sbjct: 1250 KWTAYGFVKFFTNAWCWLDFLIVAVSLVSLI 1280
Score = 37.0 bits (84), Expect = 0.011
Identities = 25/82 (30%), Positives = 43/82 (52%), Gaps = 14/82 (17%)
Query: 110 FKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFIL----EILLKW 165
F I+ L+ LN + +MVE + T +K +E ++I L+F++ E +LK
Sbjct: 1524 FDIVIMMLICLNMVTMMVETD----TQSK------QMENILYWINLVFVIFFTCECVLKM 1573
Query: 166 LSNFSVFWKSAWNVFDFVVTML 187
+ ++ WN+FDFVV +L
Sbjct: 1574 FALRHYYFTIGWNIFDFVVVIL 1595
>gi|111378393 sodium channel, voltage-gated, type VII, alpha [Homo
sapiens]
Length = 1682
Score = 47.0 bits (110), Expect = 1e-05
Identities = 29/91 (31%), Positives = 48/91 (52%), Gaps = 5/91 (5%)
Query: 104 VLECPLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILL 163
++E FK FI + L+T L E ++ T +K+ LE A IFILE+LL
Sbjct: 930 IVENNWFKCFIGLVTLLSTGTLAFEDIYMDQRKT----IKILLEYADMIFTYIFILEMLL 985
Query: 164 KWLS-NFSVFWKSAWNVFDFVVTMLVRIEIL 193
KW++ F ++ + W DFVV ++ + ++
Sbjct: 986 KWMAYGFKAYFSNGWYRLDFVVVIVFCLSLI 1016
Score = 41.2 bits (95), Expect = 6e-04
Identities = 32/146 (21%), Positives = 67/146 (45%), Gaps = 14/146 (9%)
Query: 44 IRELLDPSRQKKLVLGDQHQLVRFSIKPQRIEQISHAQRLLSRLHVRCSQRP---PLSLW 100
I ++D + K+ LG + + + Q R L +L SQRP PL+
Sbjct: 1189 ITVIIDNFNKHKIKLGGSNIFITVKQRKQ--------YRRLKKLMYEDSQRPVPRPLNKL 1240
Query: 101 AGWVLECPLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILE 160
G++ + + F + ++ L I I ++ T+ + + + L ++++ +E
Sbjct: 1241 QGFIFDVVTSQAFNVIVMVL---ICFQAIAMMIDTDVQSLQMSIALYWINSIFVMLYTME 1297
Query: 161 ILLKWLSNFSVFWKSAWNVFDFVVTM 186
+LK ++ ++ AWN+FDF+V +
Sbjct: 1298 CILKLIAFRCFYFTIAWNIFDFMVVI 1323
Score = 30.8 bits (68), Expect = 0.79
Identities = 22/98 (22%), Positives = 43/98 (43%), Gaps = 9/98 (9%)
Query: 104 VLECPLFKNFIIFLVFLNTIILMVE-IELLESTNTKLWPLKLTLEVAAWFILLIFILEIL 162
++ P F+I + LN L +E + + TNT L + + IF E++
Sbjct: 501 IIMAPFTDLFLIICIILNVCFLTLEHYPMSKQTNT-------LLNIGNLVFIGIFTAEMI 553
Query: 163 LKWLSNFSV-FWKSAWNVFDFVVTMLVRIEILRVRLVG 199
K ++ +++ WN+FD ++ IE+ + G
Sbjct: 554 FKIIAMHPYGYFQVGWNIFDSMIVFHGLIELCLANVAG 591
>gi|4506813 sodium channel, voltage-gated, type IX, alpha [Homo
sapiens]
Length = 1977
Score = 46.6 bits (109), Expect = 1e-05
Identities = 26/82 (31%), Positives = 47/82 (57%), Gaps = 5/82 (6%)
Query: 104 VLECPLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILL 163
++E F++FI+ ++ L++ L E +E T +K+ LE A IFILE+LL
Sbjct: 1177 IVEHSWFESFIVLMILLSSGALAFEDIYIERKKT----IKIILEYADKIFTYIFILEMLL 1232
Query: 164 KWLS-NFSVFWKSAWNVFDFVV 184
KW++ + ++ +AW DF++
Sbjct: 1233 KWIAYGYKTYFTNAWCWLDFLI 1254
Score = 36.6 bits (83), Expect = 0.014
Identities = 25/77 (32%), Positives = 38/77 (49%), Gaps = 12/77 (15%)
Query: 114 IIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFIL---EILLKWLSNFS 170
I+ L+ LN + +MVE E T EV W ++ IL E +LK +S
Sbjct: 1510 IMVLICLNMVTMMVEKEGQSQHMT---------EVLYWINVVFIILFTGECVLKLISLRH 1560
Query: 171 VFWKSAWNVFDFVVTML 187
++ WN+FDFVV ++
Sbjct: 1561 YYFTVGWNIFDFVVVII 1577
>gi|110349767 calcium channel, voltage-dependent, L type, alpha 1S
subunit [Homo sapiens]
Length = 1873
Score = 45.8 bits (107), Expect = 2e-05
Identities = 26/89 (29%), Positives = 44/89 (49%), Gaps = 8/89 (8%)
Query: 104 VLECPLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILL 163
++E F+ I+ +F N + L V + + E N L L LE +F L++F +E +
Sbjct: 47 IVEWKPFETIILLTIFANCVALAVYLPMPEDDNNSL---NLGLEKLEYFFLIVFSIEAAM 103
Query: 164 K-----WLSNFSVFWKSAWNVFDFVVTML 187
K +L + + +S WNV DF + L
Sbjct: 104 KIIAYGFLFHQDAYLRSGWNVLDFTIVFL 132
Score = 32.3 bits (72), Expect = 0.27
Identities = 31/116 (26%), Positives = 53/116 (45%), Gaps = 10/116 (8%)
Query: 81 QRLLSRLHVRCS-QRPPLSLWAGWVLECPLFKNFIIFLVFLNTIIL-MVEIELLESTNTK 138
Q L +RC + P +++ F+ + L+ LNTI L M E N
Sbjct: 1090 QYALKARPLRCYIPKNPYQYQVWYIVTSSYFEYLMFALIMLNTICLGMQHYNQSEQMNH- 1148
Query: 139 LWPLKLTLEVAAWFILLIFILEILLKWLS-NFSVFWKSAWNVFDFVVTMLVRIEIL 193
+ L VA +IF LE++LK ++ ++ WNVFDF++ + I+++
Sbjct: 1149 ---ISDILNVA---FTIIFTLEMILKLMAFKARGYFGDPWNVFDFLIVIGSIIDVI 1198
>gi|93587342 voltage-gated sodium channel type 4 alpha [Homo sapiens]
Length = 1836
Score = 45.4 bits (106), Expect = 3e-05
Identities = 26/82 (31%), Positives = 46/82 (56%), Gaps = 5/82 (6%)
Query: 104 VLECPLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILL 163
++E F+ FI+F++ L++ L E +E ++ LE A IFI+E+LL
Sbjct: 1027 IVEHNWFETFIVFMILLSSGALAFEDIYIEQRRV----IRTILEYADKVFTYIFIMEMLL 1082
Query: 164 KWLS-NFSVFWKSAWNVFDFVV 184
KW++ F V++ +AW DF++
Sbjct: 1083 KWVAYGFKVYFTNAWCWLDFLI 1104
Score = 38.1 bits (87), Expect = 0.005
Identities = 24/74 (32%), Positives = 39/74 (52%), Gaps = 6/74 (8%)
Query: 114 IIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILLKWLSNFSVFW 173
I+ L+ LN + +MVE + N + + + FI+ IF E +LK L+ ++
Sbjct: 1359 IMILICLNMVTMMVETD-----NQSQLKVDILYNINMIFII-IFTGECVLKMLALRQYYF 1412
Query: 174 KSAWNVFDFVVTML 187
WN+FDFVV +L
Sbjct: 1413 TVGWNIFDFVVVIL 1426
>gi|115583677 sodium channel, voltage-gated, type I, alpha [Homo
sapiens]
Length = 1998
Score = 45.4 bits (106), Expect = 3e-05
Identities = 26/82 (31%), Positives = 46/82 (56%), Gaps = 5/82 (6%)
Query: 104 VLECPLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILL 163
++E F+ FI+F++ L++ L E ++ T +K LE A IFILE+LL
Sbjct: 1203 IVEHNWFETFIVFMILLSSGALAFEDIYIDQRKT----IKTMLEYADKVFTYIFILEMLL 1258
Query: 164 KWLS-NFSVFWKSAWNVFDFVV 184
KW++ + ++ +AW DF++
Sbjct: 1259 KWVAYGYQTYFTNAWCWLDFLI 1280
Score = 37.4 bits (85), Expect = 0.008
Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 8/91 (8%)
Query: 109 LFKNFIIFLVFLNTIILMVEIE-LLESTNTKLWPLKLTLEVAAWFILLIFILEILLKWLS 167
+F I+ L+ LN + +MVE + E T L + L +++F E +LK +S
Sbjct: 1531 VFDISIMILICLNMVTMMVETDDQSEYVTTILSRINLVF-------IVLFTGECVLKLIS 1583
Query: 168 NFSVFWKSAWNVFDFVVTMLVRIEILRVRLV 198
++ WN+FDFVV +L + + L+
Sbjct: 1584 LRHYYFTIGWNIFDFVVVILSIVGMFLAELI 1614
>gi|110835710 sodium channel, voltage-gated, type X, alpha [Homo
sapiens]
Length = 1956
Score = 44.3 bits (103), Expect = 7e-05
Identities = 27/90 (30%), Positives = 48/90 (53%), Gaps = 5/90 (5%)
Query: 104 VLECPLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILL 163
++E F++FIIF++ L++ L E L+ T +K LE IF+ E+LL
Sbjct: 1148 IVEHSWFESFIIFMILLSSGSLAFEDYYLDQKPT----VKALLEYTDRVFTFIFVFEMLL 1203
Query: 164 KWLS-NFSVFWKSAWNVFDFVVTMLVRIEI 192
KW++ F ++ +AW DF++ + I +
Sbjct: 1204 KWVAYGFKKYFTNAWCWLDFLIVNISLISL 1233
Score = 44.3 bits (103), Expect = 7e-05
Identities = 38/147 (25%), Positives = 67/147 (45%), Gaps = 20/147 (13%)
Query: 47 LLDPSRQKKLVLGDQHQLVRFSIKPQRIEQISHAQRLLSRLHVRCSQRP---PLSLWAGW 103
++D Q+K LG Q + E+ + +L + Q+P PL+ + G+
Sbjct: 1417 IIDNFNQQKKKLGGQDIFMT--------EEQKKYYNAMKKLGSKKPQKPIPRPLNKFQGF 1468
Query: 104 VLECPLFKNF---IIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILE 160
V + + F I+ L+ LN I +MVE + TK+ L F + +F E
Sbjct: 1469 VFDIVTRQAFDITIMVLICLNMITMMVETDDQSEEKTKI------LGKINQFFVAVFTGE 1522
Query: 161 ILLKWLSNFSVFWKSAWNVFDFVVTML 187
++K + ++ + WNVFDF+V +L
Sbjct: 1523 CVMKMFALRQYYFTNGWNVFDFIVVVL 1549
>gi|115583667 sodium channel, voltage-gated, type XI, alpha [Homo
sapiens]
Length = 1791
Score = 43.9 bits (102), Expect = 9e-05
Identities = 47/199 (23%), Positives = 87/199 (43%), Gaps = 26/199 (13%)
Query: 3 AYQQEEQMQLPRADAIRSRLIDTFSLIEHLQGLSQAVPRHTIRELLDPSRQKKLVLGDQH 62
AY+ ++ + P + ++S ID FS E + + + +L L G
Sbjct: 946 AYELHQENKKPTSQRVQSVEIDMFSEDEPHLTIQDPRKKSDVTSILSECSTIDLQDG--- 1002
Query: 63 QLVRFSIKPQRIEQISHAQRLLSRLHVRC-------SQRPPLSLWAGWVLEC------PL 109
F P+ + + +R L + C ++PP +W C
Sbjct: 1003 ----FGWLPEMVPK-KQPERCLPKGFGCCFPCCSVDKRKPPWVIWWNLRKTCYQIVKHSW 1057
Query: 110 FKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILLKWLS-N 168
F++FIIF++ L++ L+ E LE+ K+ L ++ IFILE++LKW++
Sbjct: 1058 FESFIIFVILLSSGALIFEDVHLEN-QPKIQELLNCTDI---IFTHIFILEMVLKWVAFG 1113
Query: 169 FSVFWKSAWNVFDFVVTML 187
F ++ SAW DF++ ++
Sbjct: 1114 FGKYFTSAWCCLDFIIVIV 1132
Score = 43.1 bits (100), Expect = 2e-04
Identities = 32/110 (29%), Positives = 54/110 (49%), Gaps = 12/110 (10%)
Query: 84 LSRLHVRCSQRP---PLSLWAGWVLEC---PLFKNFIIFLVFLNTIILMVEIELLESTNT 137
+ +L + Q+P PL+ G V + +F II L+ LN I +M E +
Sbjct: 1336 MKKLGSKKPQKPIPRPLNKCQGLVFDIVTSQIFDIIIISLIILNMISMMAE------SYN 1389
Query: 138 KLWPLKLTLEVAAWFILLIFILEILLKWLSNFSVFWKSAWNVFDFVVTML 187
+ +K L+ W ++IF LE L+K + ++ + WN+FD VV +L
Sbjct: 1390 QPKAMKSILDHLNWVFVVIFTLECLIKIFALRQYYFTNGWNLFDCVVVLL 1439
Score = 34.7 bits (78), Expect = 0.055
Identities = 22/91 (24%), Positives = 45/91 (49%), Gaps = 7/91 (7%)
Query: 104 VLECPLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILL 163
V+ P + I + +NT+ L +E +E++ K+ L + IFI E+ L
Sbjct: 573 VMTDPFTELAITICIIINTVFLAMEHHKMEASFEKM------LNIGNLVFTSIFIAEMCL 626
Query: 164 KWLSNFSV-FWKSAWNVFDFVVTMLVRIEIL 193
K ++ +++ WN+FD +V +L +++
Sbjct: 627 KIIALDPYHYFRRGWNIFDSIVALLSFADVM 657
>gi|239748090 PREDICTED: similar to sodium channel, voltage-gated,
type V, alpha (long QT syndrome 3) [Homo sapiens]
Length = 1637
Score = 40.8 bits (94), Expect = 8e-04
Identities = 36/147 (24%), Positives = 72/147 (48%), Gaps = 20/147 (13%)
Query: 47 LLDPSRQKKLVLGDQHQLVRFSIKPQRIEQISHAQRLLSRLHVRCSQRP---PLSLWAGW 103
++D Q+K LG Q + E+ + +L + Q+P PL+ + G+
Sbjct: 1078 IIDNFNQQKKKLGGQDIFMT--------EEQKKYYNAMKKLGSKKPQKPIPRPLNKYQGF 1129
Query: 104 VLECPLFKNF---IIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILE 160
+ + + F I+FL+ LN + +MVE + + + K+ + ++ F+ IF E
Sbjct: 1130 IFDIVTKQAFDVTIMFLICLNMVTMMVETD--DQSPEKI---NILAKINLLFVA-IFTGE 1183
Query: 161 ILLKWLSNFSVFWKSAWNVFDFVVTML 187
++K + ++ ++WN+FDFVV +L
Sbjct: 1184 CIVKLAALRHYYFTNSWNIFDFVVVIL 1210
Score = 35.8 bits (81), Expect = 0.025
Identities = 16/44 (36%), Positives = 28/44 (63%), Gaps = 1/44 (2%)
Query: 142 LKLTLEVAAWFILLIFILEILLKWLS-NFSVFWKSAWNVFDFVV 184
+K+ LE A +F+LE+LLKW++ F ++ +AW DF++
Sbjct: 844 IKVLLEYADKMFTYVFVLEMLLKWVAYGFKKYFTNAWCWLDFLI 887
>gi|53832005 calcium channel, voltage-dependent, R type, alpha 1E
subunit [Homo sapiens]
Length = 2270
Score = 39.3 bits (90), Expect = 0.002
Identities = 24/87 (27%), Positives = 46/87 (52%), Gaps = 7/87 (8%)
Query: 108 PLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILLKWLS 167
P F+ I+ ++ LNT++LM++ T +L L+ ++F LE +LK ++
Sbjct: 1478 PSFEYTIMAMIALNTVVLMMKYYSAPCT------YELALKYLNIAFTMVFSLECVLKVIA 1531
Query: 168 -NFSVFWKSAWNVFDFVVTMLVRIEIL 193
F +++ WN+FDF+ + EI+
Sbjct: 1532 FGFLNYFRDTWNIFDFITVIGSITEII 1558
Score = 38.1 bits (87), Expect = 0.005
Identities = 26/92 (28%), Positives = 45/92 (48%), Gaps = 8/92 (8%)
Query: 100 WAGWVLECPLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFIL 159
+A +++ P F+ I+ + N I+L +E L E T P+ LE + + IF
Sbjct: 81 YAKKLIDWPPFEYMILATIIANCIVLALEQHLPEDDKT---PMSRRLEKTEPYFIGIFCF 137
Query: 160 EILLKWLSNFSVFWKSA-----WNVFDFVVTM 186
E +K ++ +F K + WNV DF+V +
Sbjct: 138 EAGIKIVALGFIFHKGSYLRNGWNVMDFIVVL 169
>gi|4502523 calcium channel, voltage-dependent, N type, alpha 1B
subunit [Homo sapiens]
Length = 2339
Score = 38.5 bits (88), Expect = 0.004
Identities = 25/81 (30%), Positives = 45/81 (55%), Gaps = 9/81 (11%)
Query: 108 PLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILLKWLS 167
P F+ FI+ ++ LNT++LM++ + +L L+ +F +E +LK ++
Sbjct: 1471 PPFEYFIMAMIALNTVVLMMKFY------DAPYEYELMLKCLNIVFTSMFSMECVLKIIA 1524
Query: 168 NFSV--FWKSAWNVFDFVVTM 186
F V +++ AWNVFDFV +
Sbjct: 1525 -FGVLNYFRDAWNVFDFVTVL 1544
Score = 37.0 bits (84), Expect = 0.011
Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 8/92 (8%)
Query: 100 WAGWVLECPLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFIL 159
+A + E P F+ I+ + N I+L +E L + T P+ L+ + + IF
Sbjct: 87 YAKRITEWPPFEYMILATIIANCIVLALEQHLPDGDKT---PMSERLDDTEPYFIGIFCF 143
Query: 160 EILLKWLSNFSVFWKSA-----WNVFDFVVTM 186
E +K ++ VF K + WNV DFVV +
Sbjct: 144 EAGIKIIALGFVFHKGSYLRNGWNVMDFVVVL 175
>gi|20070163 voltage-dependent calcium channel alpha 1G subunit
isoform 1 [Homo sapiens]
Length = 2377
Score = 37.4 bits (85), Expect = 0.008
Identities = 19/90 (21%), Positives = 48/90 (53%), Gaps = 9/90 (10%)
Query: 109 LFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILLK---- 164
+F + ++ ++FLN I + +E ++ + + ++ L ++ + +F+ E+ +K
Sbjct: 1277 MFDHVVLVIIFLNCITIAMERPKIDPHSAE----RIFLTLSNYIFTAVFLAEMTVKVVAL 1332
Query: 165 -WLSNFSVFWKSAWNVFDFVVTMLVRIEIL 193
W + +S+WNV D ++ ++ I+IL
Sbjct: 1333 GWCFGEQAYLRSSWNVLDGLLVLISVIDIL 1362
>gi|38505294 voltage-dependent calcium channel alpha 1G subunit
isoform 15 [Homo sapiens]
Length = 1555
Score = 37.4 bits (85), Expect = 0.008
Identities = 19/90 (21%), Positives = 48/90 (53%), Gaps = 9/90 (10%)
Query: 109 LFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILLK---- 164
+F + ++ ++FLN I + +E ++ + + ++ L ++ + +F+ E+ +K
Sbjct: 1277 MFDHVVLVIIFLNCITIAMERPKIDPHSAE----RIFLTLSNYIFTAVFLAEMTVKVVAL 1332
Query: 165 -WLSNFSVFWKSAWNVFDFVVTMLVRIEIL 193
W + +S+WNV D ++ ++ I+IL
Sbjct: 1333 GWCFGEQAYLRSSWNVLDGLLVLISVIDIL 1362
>gi|38505292 voltage-dependent calcium channel alpha 1G subunit
isoform 3 [Homo sapiens]
Length = 2343
Score = 37.4 bits (85), Expect = 0.008
Identities = 19/90 (21%), Positives = 48/90 (53%), Gaps = 9/90 (10%)
Query: 109 LFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEILLK---- 164
+F + ++ ++FLN I + +E ++ + + ++ L ++ + +F+ E+ +K
Sbjct: 1254 MFDHVVLVIIFLNCITIAMERPKIDPHSAE----RIFLTLSNYIFTAVFLAEMTVKVVAL 1309
Query: 165 -WLSNFSVFWKSAWNVFDFVVTMLVRIEIL 193
W + +S+WNV D ++ ++ I+IL
Sbjct: 1310 GWCFGEQAYLRSSWNVLDGLLVLISVIDIL 1339
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.330 0.141 0.435
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,873,505
Number of Sequences: 37866
Number of extensions: 266170
Number of successful extensions: 1012
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 45
Number of HSP's that attempted gapping in prelim test: 820
Number of HSP's gapped (non-prelim): 202
length of query: 199
length of database: 18,247,518
effective HSP length: 97
effective length of query: 102
effective length of database: 14,574,516
effective search space: 1486600632
effective search space used: 1486600632
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.