Guide to the Human Genome
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Search of human proteins with 25188181

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|25188181 WAP four-disulfide core domain 13 precursor [Homo
sapiens]
         (93 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|25188181 WAP four-disulfide core domain 13 precursor [Homo sa...   200   2e-52
gi|21703706 WAP four-disulfide core domain 10A precursor [Homo s...    45   1e-05
gi|26006869 WAP four-disulfide core domain 10B isoform a precurs...    40   5e-04
gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and n...    39   0.001
gi|56699495 WAP four-disulfide core domain 2 precursor [Homo sap...    37   0.003
gi|26006867 WAP four-disulfide core domain 10B isoform b [Homo s...    37   0.004
gi|32307109 WAP four-disulfide core domain 3 precursor [Homo sap...    35   0.013
gi|22218355 WAP four-disulfide core domain 11 precursor [Homo sa...    33   0.038
gi|116256475 zinc finger protein 827 [Homo sapiens]                    33   0.065
gi|153946389 WAP four-disulfide core domain 8 precursor [Homo sa...    30   0.32 
gi|153946387 WAP four-disulfide core domain 8 precursor [Homo sa...    30   0.32 
gi|148539593 sushi domain containing 4 isoform a [Homo sapiens]        30   0.55 
gi|21717822 WAP four-disulfide core domain 5 precursor [Homo sap...    30   0.55 
gi|4507065 secretory leukocyte peptidase inhibitor precursor [Ho...    29   0.71 
gi|28212222 WFIKKN2 protein [Homo sapiens]                             29   0.71 
gi|38490571 keratin associated protein 10-7 [Homo sapiens]             29   0.71 
gi|119395746 Kallmann syndrome 1 protein precursor [Homo sapiens]      29   0.93 
gi|239752100 PREDICTED: hypothetical protein [Homo sapiens]            28   1.2  
gi|239746604 PREDICTED: similar to Keratin-associated protein 10...    28   1.2  
gi|238859649 keratin associated protein 10-8 [Homo sapiens]            28   1.6  
gi|183396797 keratin associated protein KRTAP2.1A [Homo sapiens]       28   1.6  
gi|15082232 keratin associated protein 2-4 [Homo sapiens]              28   1.6  
gi|225690576 keratin associated protein 2-2 [Homo sapiens]             28   1.6  
gi|113427417 PREDICTED: similar to keratin associated protein 2-...    28   1.6  
gi|18379353 WAP four-disulfide core domain 1 precursor [Homo sap...    28   2.1  
gi|153946395 tenascin C precursor [Homo sapiens]                       27   2.7  
gi|41327754 ankyrin repeat domain 3 [Homo sapiens]                     27   2.7  
gi|63053515 keratin associated protein 10-3 [Homo sapiens]             27   2.7  
gi|23397498 transmembrane protein 92 [Homo sapiens]                    27   2.7  
gi|61744435 phosphodiesterase 5A isoform 1 [Homo sapiens]              27   3.5  

>gi|25188181 WAP four-disulfide core domain 13 precursor [Homo
          sapiens]
          Length = 93

 Score =  200 bits (509), Expect = 2e-52
 Identities = 93/93 (100%), Positives = 93/93 (100%)

Query: 1  MKPVLPLQFLVVFCLALQLVPGSPKQRVLKYILEPPPCISAPENCTHLCTMQEDCEKGFQ 60
          MKPVLPLQFLVVFCLALQLVPGSPKQRVLKYILEPPPCISAPENCTHLCTMQEDCEKGFQ
Sbjct: 1  MKPVLPLQFLVVFCLALQLVPGSPKQRVLKYILEPPPCISAPENCTHLCTMQEDCEKGFQ 60

Query: 61 CCSSFCGIVCSSETFQKRNRIKHKGSEVIMPAN 93
          CCSSFCGIVCSSETFQKRNRIKHKGSEVIMPAN
Sbjct: 61 CCSSFCGIVCSSETFQKRNRIKHKGSEVIMPAN 93


>gi|21703706 WAP four-disulfide core domain 10A precursor [Homo
          sapiens]
          Length = 79

 Score = 45.1 bits (105), Expect = 1e-05
 Identities = 30/77 (38%), Positives = 37/77 (48%), Gaps = 5/77 (6%)

Query: 1  MKPVLPLQFLVVFCLALQLVPG-SPKQRVLKYILEPP--PCISAPEN--CTHLCTMQEDC 55
          M P   L  LV+  L LQ   G   K+R+ K  L P    C   P+   C HLC    DC
Sbjct: 1  MAPQTLLPVLVLCVLLLQAQGGYRDKKRMQKTQLSPEIKVCQQQPKLYLCKHLCESHRDC 60

Query: 56 EKGFQCCSSFCGIVCSS 72
          +    CCS++CG VC S
Sbjct: 61 QANNICCSTYCGNVCMS 77


>gi|26006869 WAP four-disulfide core domain 10B isoform a
          precursor [Homo sapiens]
          Length = 73

 Score = 39.7 bits (91), Expect = 5e-04
 Identities = 27/74 (36%), Positives = 35/74 (47%), Gaps = 5/74 (6%)

Query: 1  MKPVLPLQFLVVFCLALQLVPG-SPKQRVLKY-ILEPPPCISAPENCTHLCTMQEDCEKG 58
          M P   L  LV+  L LQ   G   K R+ +  + E  P I     C H C+  + CE  
Sbjct: 1  MAPQTLLLVLVLCVLLLQAQGGYRDKMRMQRIKVCEKRPSIDL---CIHHCSYFQKCETN 57

Query: 59 FQCCSSFCGIVCSS 72
            CCS+FCG +C S
Sbjct: 58 KICCSAFCGNICMS 71


>gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and
          netrin domain containing 1 precursor [Homo sapiens]
          Length = 548

 Score = 38.9 bits (89), Expect = 0.001
 Identities = 20/69 (28%), Positives = 31/69 (44%), Gaps = 1/69 (1%)

Query: 1  MKPVLPLQFLVVFCLALQLVPG-SPKQRVLKYILEPPPCISAPENCTHLCTMQEDCEKGF 59
          ++P+LPL  L+       L+PG      V    L P   + A   C   C+  +DC    
Sbjct: 4  LRPLLPLLLLLRLTSGAGLLPGLGSHPGVCPNQLSPNLWVDAQSTCERECSRDQDCAAAE 63

Query: 60 QCCSSFCGI 68
          +CC + CG+
Sbjct: 64 KCCINVCGL 72


>gi|56699495 WAP four-disulfide core domain 2 precursor [Homo
          sapiens]
          Length = 124

 Score = 37.4 bits (85), Expect = 0.003
 Identities = 13/35 (37%), Positives = 18/35 (51%)

Query: 37 PCISAPENCTHLCTMQEDCEKGFQCCSSFCGIVCS 71
          P + A +NCT  C    +C    +CCS+ C   CS
Sbjct: 37 PELQADQNCTQECVSDSECADNLKCCSAGCATFCS 71


>gi|26006867 WAP four-disulfide core domain 10B isoform b [Homo
          sapiens]
          Length = 89

 Score = 36.6 bits (83), Expect = 0.004
 Identities = 13/28 (46%), Positives = 17/28 (60%)

Query: 45 CTHLCTMQEDCEKGFQCCSSFCGIVCSS 72
          C H C+  + CE    CCS+FCG +C S
Sbjct: 60 CIHHCSYFQKCETNKICCSAFCGNICMS 87


>gi|32307109 WAP four-disulfide core domain 3 precursor [Homo
           sapiens]
          Length = 231

 Score = 35.0 bits (79), Expect = 0.013
 Identities = 13/33 (39%), Positives = 17/33 (51%)

Query: 38  CISAPENCTHLCTMQEDCEKGFQCCSSFCGIVC 70
           C + P  C  LC     C +G +CCS+ CG  C
Sbjct: 126 CPADPLPCEELCDGDASCPQGHKCCSTGCGRTC 158



 Score = 33.1 bits (74), Expect = 0.049
 Identities = 12/26 (46%), Positives = 15/26 (57%)

Query: 45  CTHLCTMQEDCEKGFQCCSSFCGIVC 70
           C   C M E+C+ G +CC S CG  C
Sbjct: 178 CIVGCVMDENCQAGEKCCKSGCGRFC 203



 Score = 28.5 bits (62), Expect = 1.2
 Identities = 10/26 (38%), Positives = 14/26 (53%)

Query: 45 CTHLCTMQEDCEKGFQCCSSFCGIVC 70
          C  LC   E C    +CC++ CG +C
Sbjct: 40 CKELCQGDELCPAEQKCCTTGCGRIC 65


>gi|22218355 WAP four-disulfide core domain 11 precursor [Homo
          sapiens]
          Length = 87

 Score = 33.5 bits (75), Expect = 0.038
 Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 5/74 (6%)

Query: 1  MKPVLPLQFLVVFCLALQLVPGSP-KQRVLKYILEPPPCISAP--ENCTHLCTMQEDC-E 56
          MK  +P+  +  FC  L  V G   K+R  +  L    C   P  + CT+ C+    C +
Sbjct: 5  MKLWIPM-LMTFFCTVLLSVLGEMRKKRYDRKELLLEECWGKPNVKECTNKCSKAFRCKD 63

Query: 57 KGFQCCSSFCGIVC 70
          K + CC ++CG +C
Sbjct: 64 KNYTCCWTYCGNIC 77


>gi|116256475 zinc finger protein 827 [Homo sapiens]
          Length = 1077

 Score = 32.7 bits (73), Expect = 0.065
 Identities = 21/67 (31%), Positives = 33/67 (49%), Gaps = 8/67 (11%)

Query: 21  PGSPKQRVLKYILEPPPC--ISAPENCTHLCTMQEDCEKGFQCCSSFCGIVCSSETFQKR 78
           P  P  + L+ +L P P   +S P N       +E+  K FQC    CG+V   +++ KR
Sbjct: 338 PPPPPPQSLELLLLPVPKGRVSKPSNSAS----EEESGKPFQC--PICGLVIKRKSYWKR 391

Query: 79  NRIKHKG 85
           + + H G
Sbjct: 392 HMVIHTG 398


>gi|153946389 WAP four-disulfide core domain 8 precursor [Homo
           sapiens]
          Length = 241

 Score = 30.4 bits (67), Expect = 0.32
 Identities = 11/29 (37%), Positives = 15/29 (51%)

Query: 43  ENCTHLCTMQEDCEKGFQCCSSFCGIVCS 71
           + C   C    DC +  +CC S CG VC+
Sbjct: 163 KECPPSCHSDIDCPQTDKCCESRCGFVCA 191


>gi|153946387 WAP four-disulfide core domain 8 precursor [Homo
           sapiens]
          Length = 241

 Score = 30.4 bits (67), Expect = 0.32
 Identities = 11/29 (37%), Positives = 15/29 (51%)

Query: 43  ENCTHLCTMQEDCEKGFQCCSSFCGIVCS 71
           + C   C    DC +  +CC S CG VC+
Sbjct: 163 KECPPSCHSDIDCPQTDKCCESRCGFVCA 191


>gi|148539593 sushi domain containing 4 isoform a [Homo sapiens]
          Length = 490

 Score = 29.6 bits (65), Expect = 0.55
 Identities = 16/57 (28%), Positives = 25/57 (43%), Gaps = 4/57 (7%)

Query: 14  CLALQLVPGSPKQRVLKYILEPPPCISAPENCTHLCTMQEDCEKGFQCCSSFCGIVC 70
           CLAL++ P  P      ++  P PC    E   H   ++  C+ G+   S +  I C
Sbjct: 237 CLALEVCPLPPMVSHGDFVCHPRPC----ERYNHGTVVEFYCDPGYSLTSDYKYITC 289


>gi|21717822 WAP four-disulfide core domain 5 precursor [Homo
           sapiens]
          Length = 123

 Score = 29.6 bits (65), Expect = 0.55
 Identities = 15/33 (45%), Positives = 17/33 (51%), Gaps = 3/33 (9%)

Query: 38  CISAPENCTHLCTMQEDCEKGFQCCSSFCGIVC 70
           C+S P N  HLC    DC    +CC S CG  C
Sbjct: 88  CLS-PMN--HLCHKDSDCSGKKRCCHSACGRDC 117


>gi|4507065 secretory leukocyte peptidase inhibitor precursor [Homo
           sapiens]
          Length = 132

 Score = 29.3 bits (64), Expect = 0.71
 Identities = 10/29 (34%), Positives = 14/29 (48%)

Query: 44  NCTHLCTMQEDCEKGFQCCSSFCGIVCSS 72
           N  + C M   C++  +CC   CG  C S
Sbjct: 100 NPPNFCEMDGQCKRDLKCCMGMCGKSCVS 128


>gi|28212222 WFIKKN2 protein [Homo sapiens]
          Length = 576

 Score = 29.3 bits (64), Expect = 0.71
 Identities = 10/35 (28%), Positives = 16/35 (45%)

Query: 33 LEPPPCISAPENCTHLCTMQEDCEKGFQCCSSFCG 67
          + P   + A   C   C   ++CE   +CC + CG
Sbjct: 50 MNPNLWVDAQSTCRRECETDQECETYEKCCPNVCG 84


>gi|38490571 keratin associated protein 10-7 [Homo sapiens]
          Length = 370

 Score = 29.3 bits (64), Expect = 0.71
 Identities = 13/51 (25%), Positives = 19/51 (37%)

Query: 21  PGSPKQRVLKYILEPPPCISAPENCTHLCTMQEDCEKGFQCCSSFCGIVCS 71
           P S    + + +  P  C+  P  C    + Q  C +   C S  C   CS
Sbjct: 305 PSSSVSLLCRPVCRPACCVPVPSCCAPTSSCQASCCRPASCVSLLCRPACS 355


>gi|119395746 Kallmann syndrome 1 protein precursor [Homo sapiens]
          Length = 680

 Score = 28.9 bits (63), Expect = 0.93
 Identities = 18/51 (35%), Positives = 23/51 (45%), Gaps = 10/51 (19%)

Query: 29  LKYIL--EPPPCISAPEN-------CTHLCTMQEDCEKGFQCCSSFCGIVC 70
           LKYIL  +   C  APE        C   C +  +C    +CCS+ CG  C
Sbjct: 123 LKYILLVKQGDC-PAPEKASGFAAACVESCEVDNECSGVKKCCSNGCGHTC 172


>gi|239752100 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 312

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 13/31 (41%), Positives = 16/31 (51%), Gaps = 5/31 (16%)

Query: 37  PCISA---PENCTHLCTMQEDCEKGFQCCSS 64
           PC  A   P +CT LC  Q  C+    CC+S
Sbjct: 178 PCCQAACEPSSCTPLCCQQSSCQPA--CCTS 206



 Score = 27.3 bits (59), Expect = 2.7
 Identities = 14/51 (27%), Positives = 18/51 (35%)

Query: 21  PGSPKQRVLKYILEPPPCISAPENCTHLCTMQEDCEKGFQCCSSFCGIVCS 71
           P S    +   +  P  C+  P  C    + Q  C     C S  C  VCS
Sbjct: 258 PSSSVSLLCHPVCRPTCCMPVPSCCAPAFSCQPSCCHPASCVSLLCRPVCS 308


>gi|239746604 PREDICTED: similar to Keratin-associated protein 10-8
           [Homo sapiens]
          Length = 312

 Score = 28.5 bits (62), Expect = 1.2
 Identities = 13/31 (41%), Positives = 16/31 (51%), Gaps = 5/31 (16%)

Query: 37  PCISA---PENCTHLCTMQEDCEKGFQCCSS 64
           PC  A   P +CT LC  Q  C+    CC+S
Sbjct: 178 PCCQAACEPSSCTPLCCQQSSCQPA--CCTS 206



 Score = 27.3 bits (59), Expect = 2.7
 Identities = 14/51 (27%), Positives = 18/51 (35%)

Query: 21  PGSPKQRVLKYILEPPPCISAPENCTHLCTMQEDCEKGFQCCSSFCGIVCS 71
           P S    +   +  P  C+  P  C    + Q  C     C S  C  VCS
Sbjct: 258 PSSSVSLLCHPVCRPTCCMPVPSCCAPAFSCQPSCCHPASCVSLLCRRVCS 308


>gi|238859649 keratin associated protein 10-8 [Homo sapiens]
          Length = 259

 Score = 28.1 bits (61), Expect = 1.6
 Identities = 13/51 (25%), Positives = 18/51 (35%)

Query: 21  PGSPKQRVLKYILEPPPCISAPENCTHLCTMQEDCEKGFQCCSSFCGIVCS 71
           P S    + + +  P  C+  P  C    + Q  C     C S  C   CS
Sbjct: 205 PSSSVSLLCRPVCRPACCVPVPSCCVPASSCQPSCCHPASCLSFLCRPACS 255


>gi|183396797 keratin associated protein KRTAP2.1A [Homo sapiens]
          Length = 128

 Score = 28.1 bits (61), Expect = 1.6
 Identities = 11/27 (40%), Positives = 15/27 (55%), Gaps = 1/27 (3%)

Query: 45 CTHLCTMQEDCEKGFQCCSSFC-GIVC 70
          C   C++QE C +   CC S C  +VC
Sbjct: 63 CCDPCSLQEGCCRPITCCPSSCTAVVC 89


>gi|15082232 keratin associated protein 2-4 [Homo sapiens]
          Length = 128

 Score = 28.1 bits (61), Expect = 1.6
 Identities = 11/27 (40%), Positives = 15/27 (55%), Gaps = 1/27 (3%)

Query: 45 CTHLCTMQEDCEKGFQCCSSFC-GIVC 70
          C   C++QE C +   CC S C  +VC
Sbjct: 63 CCDPCSLQEGCCRPITCCPSSCTAVVC 89


>gi|225690576 keratin associated protein 2-2 [Homo sapiens]
          Length = 123

 Score = 28.1 bits (61), Expect = 1.6
 Identities = 11/27 (40%), Positives = 15/27 (55%), Gaps = 1/27 (3%)

Query: 45 CTHLCTMQEDCEKGFQCCSSFC-GIVC 70
          C   C++QE C +   CC S C  +VC
Sbjct: 63 CCDPCSLQEGCCRPITCCPSSCTAVVC 89


>gi|113427417 PREDICTED: similar to keratin associated protein 2-4
          [Homo sapiens]
          Length = 128

 Score = 28.1 bits (61), Expect = 1.6
 Identities = 11/27 (40%), Positives = 15/27 (55%), Gaps = 1/27 (3%)

Query: 45 CTHLCTMQEDCEKGFQCCSSFC-GIVC 70
          C   C++QE C +   CC S C  +VC
Sbjct: 63 CCDPCSLQEGCCRPITCCPSSCTAVVC 89


>gi|18379353 WAP four-disulfide core domain 1 precursor [Homo
           sapiens]
          Length = 220

 Score = 27.7 bits (60), Expect = 2.1
 Identities = 15/51 (29%), Positives = 20/51 (39%), Gaps = 2/51 (3%)

Query: 21  PGSPKQRVLKYILEPPPCISAPENCTHL-CTMQEDCEKGFQCCSSFCGIVC 70
           PG P+Q        PPP    P  C    C    +C +  +CC + C   C
Sbjct: 55  PGGPRQPRADRC-PPPPRTLPPGACQAARCQADSECPRHRRCCYNGCAYAC 104


>gi|153946395 tenascin C precursor [Homo sapiens]
          Length = 2201

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 12/30 (40%), Positives = 15/30 (50%), Gaps = 1/30 (3%)

Query: 45  CTHLCTMQEDCEKG-FQCCSSFCGIVCSSE 73
           C H C  Q  CE+G   C   F G+ CS +
Sbjct: 346 CPHACHTQGRCEEGQCVCDEGFAGVDCSEK 375


>gi|41327754 ankyrin repeat domain 3 [Homo sapiens]
          Length = 784

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 13/58 (22%), Positives = 29/58 (50%), Gaps = 9/58 (15%)

Query: 10  LVVFCLALQLVPGSPKQRVLKYILE---------PPPCISAPENCTHLCTMQEDCEKG 58
           +V++ +  Q  P + ++ +L  +++         PP C + P  C+HL  + + C +G
Sbjct: 211 IVIWGVLTQKKPFADEKNILHIMVKVVKGHRPELPPVCRARPRACSHLIRLMQRCWQG 268


>gi|63053515 keratin associated protein 10-3 [Homo sapiens]
          Length = 221

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 13/51 (25%), Positives = 18/51 (35%)

Query: 21  PGSPKQRVLKYILEPPPCISAPENCTHLCTMQEDCEKGFQCCSSFCGIVCS 71
           P S    + + +     C+  P  C    T Q  C +   C S  C   CS
Sbjct: 154 PSSSVSLLCRPVCRSTCCVPIPSCCAPASTCQPSCCRPASCVSLLCRPTCS 204


>gi|23397498 transmembrane protein 92 [Homo sapiens]
          Length = 159

 Score = 27.3 bits (59), Expect = 2.7
 Identities = 9/28 (32%), Positives = 14/28 (50%)

Query: 39 ISAPENCTHLCTMQEDCEKGFQCCSSFC 66
          ++ P+     C +   C KGF+CC   C
Sbjct: 18 LAGPQKIAAKCGLILACPKGFKCCGDSC 45


>gi|61744435 phosphodiesterase 5A isoform 1 [Homo sapiens]
          Length = 875

 Score = 26.9 bits (58), Expect = 3.5
 Identities = 12/41 (29%), Positives = 23/41 (56%)

Query: 50  TMQEDCEKGFQCCSSFCGIVCSSETFQKRNRIKHKGSEVIM 90
           T  E  EK F    +FCGIV  +    + + +++K ++V++
Sbjct: 294 TFTEKDEKDFAAYLAFCGIVLHNAQLYETSLLENKRNQVLL 334


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.139    0.457 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,726,350
Number of Sequences: 37866
Number of extensions: 231573
Number of successful extensions: 853
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 21
Number of HSP's that attempted gapping in prelim test: 785
Number of HSP's gapped (non-prelim): 93
length of query: 93
length of database: 18,247,518
effective HSP length: 64
effective length of query: 29
effective length of database: 15,824,094
effective search space: 458898726
effective search space used: 458898726
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 55 (25.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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