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Search of human proteins with 24797086
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24797086 importin 5 [Homo sapiens]
(1115 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24797086 importin 5 [Homo sapiens] 2230 0.0
gi|45331213 RAN binding protein 6 [Homo sapiens] 1788 0.0
gi|62460637 importin 4 [Homo sapiens] 167 4e-41
gi|23510381 transportin 1 isoform 2 [Homo sapiens] 77 1e-13
gi|133925811 transportin 1 isoform 1 [Homo sapiens] 77 1e-13
gi|19923142 karyopherin beta 1 [Homo sapiens] 69 3e-11
gi|209969838 transportin 2 (importin 3, karyopherin beta 2b) iso... 67 7e-11
gi|209969836 transportin 2 (importin 3, karyopherin beta 2b) iso... 67 7e-11
gi|48675813 transportin 2 (importin 3, karyopherin beta 2b) isof... 67 7e-11
gi|54112117 splicing factor 3b, subunit 1 isoform 1 [Homo sapiens] 38 0.047
gi|118918407 spectrin repeat containing, nuclear envelope 2 isof... 37 0.14
gi|118918403 spectrin repeat containing, nuclear envelope 2 isof... 37 0.14
gi|6912734 transportin 3 [Homo sapiens] 35 0.30
gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens] 35 0.52
gi|241982712 TBP-interacting protein isoform 1 [Homo sapiens] 34 0.68
gi|112420977 TBP-interacting protein isoform 2 [Homo sapiens] 34 0.68
gi|42558270 HEAT repeat containing 4 [Homo sapiens] 34 0.68
gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens] 34 0.88
gi|6912678 sperm associated antigen 6 isoform 1 [Homo sapiens] 34 0.88
gi|27262641 sperm associated antigen 6 isoform 2 [Homo sapiens] 34 0.88
gi|22094987 raptor isoform 1 [Homo sapiens] 33 1.2
gi|145587088 hypothetical protein LOC165186 [Homo sapiens] 33 1.2
gi|4826730 FK506 binding protein 12-rapamycin associated protein... 33 2.0
gi|21361794 TIP120 protein [Homo sapiens] 32 2.6
gi|21237808 SWI/SNF-related matrix-associated actin-dependent re... 32 2.6
gi|194363725 SWI/SNF-related matrix-associated actin-dependent r... 32 2.6
gi|194578923 sperm associated antigen 9 isoform 1 [Homo sapiens] 32 3.4
gi|27436920 sperm associated antigen 9 isoform 3 [Homo sapiens] 32 3.4
gi|109715866 FERM domain containing 6 [Homo sapiens] 32 3.4
gi|22748721 FERM domain containing 6 [Homo sapiens] 32 3.4
>gi|24797086 importin 5 [Homo sapiens]
Length = 1115
Score = 2230 bits (5779), Expect = 0.0
Identities = 1115/1115 (100%), Positives = 1115/1115 (100%)
Query: 1 MPEDQVGKLEATENTISAMAAAAAEQQQFYLLLGNLLSPDNVVRKQAEETYENIPGQSKI 60
MPEDQVGKLEATENTISAMAAAAAEQQQFYLLLGNLLSPDNVVRKQAEETYENIPGQSKI
Sbjct: 1 MPEDQVGKLEATENTISAMAAAAAEQQQFYLLLGNLLSPDNVVRKQAEETYENIPGQSKI 60
Query: 61 TFLLQAIRNTTAAEEARQMAAVLLRRLLSSAFDEVYPALPSDVQTAIKSELLMIIQMETQ 120
TFLLQAIRNTTAAEEARQMAAVLLRRLLSSAFDEVYPALPSDVQTAIKSELLMIIQMETQ
Sbjct: 61 TFLLQAIRNTTAAEEARQMAAVLLRRLLSSAFDEVYPALPSDVQTAIKSELLMIIQMETQ 120
Query: 121 SSMRKKVCDIAAELARNLIDEDGNNQWPEGLKFLFDSVSSQNVGLREAALHIFWNFPGIF 180
SSMRKKVCDIAAELARNLIDEDGNNQWPEGLKFLFDSVSSQNVGLREAALHIFWNFPGIF
Sbjct: 121 SSMRKKVCDIAAELARNLIDEDGNNQWPEGLKFLFDSVSSQNVGLREAALHIFWNFPGIF 180
Query: 181 GNQQQHYLDVIKRMLVQCMQDQEHPSIRTLSARATAAFILANEHNVALFKHFADLLPGFL 240
GNQQQHYLDVIKRMLVQCMQDQEHPSIRTLSARATAAFILANEHNVALFKHFADLLPGFL
Sbjct: 181 GNQQQHYLDVIKRMLVQCMQDQEHPSIRTLSARATAAFILANEHNVALFKHFADLLPGFL 240
Query: 241 QAVNDSCYQNDDSVLKSLVEIADTVPKYLRPHLEATLQLSLKLCGDTSLNNMQRQLALEV 300
QAVNDSCYQNDDSVLKSLVEIADTVPKYLRPHLEATLQLSLKLCGDTSLNNMQRQLALEV
Sbjct: 241 QAVNDSCYQNDDSVLKSLVEIADTVPKYLRPHLEATLQLSLKLCGDTSLNNMQRQLALEV 300
Query: 301 IVTLSETAAAMLRKHTNIVAQTIPQMLAMMVDLEEDEDWANADELEDDDFDSNAVAGESA 360
IVTLSETAAAMLRKHTNIVAQTIPQMLAMMVDLEEDEDWANADELEDDDFDSNAVAGESA
Sbjct: 301 IVTLSETAAAMLRKHTNIVAQTIPQMLAMMVDLEEDEDWANADELEDDDFDSNAVAGESA 360
Query: 361 LDRMACGLGGKLVLPMIKEHIMQMLQNPDWKYRHAGLMALSAIGEGCHQQMEGILNEIVN 420
LDRMACGLGGKLVLPMIKEHIMQMLQNPDWKYRHAGLMALSAIGEGCHQQMEGILNEIVN
Sbjct: 361 LDRMACGLGGKLVLPMIKEHIMQMLQNPDWKYRHAGLMALSAIGEGCHQQMEGILNEIVN 420
Query: 421 FVLLFLQDPHPRVRYAACNAVGQMATDFAPGFQKKFHEKVIAALLQTMEDQGNQRVQAHA 480
FVLLFLQDPHPRVRYAACNAVGQMATDFAPGFQKKFHEKVIAALLQTMEDQGNQRVQAHA
Sbjct: 421 FVLLFLQDPHPRVRYAACNAVGQMATDFAPGFQKKFHEKVIAALLQTMEDQGNQRVQAHA 480
Query: 481 AAALINFTEDCPKSLLIPYLDNLVKHLHSIMVLKLQELIQKGTKLVLEQVVTSIASVADT 540
AAALINFTEDCPKSLLIPYLDNLVKHLHSIMVLKLQELIQKGTKLVLEQVVTSIASVADT
Sbjct: 481 AAALINFTEDCPKSLLIPYLDNLVKHLHSIMVLKLQELIQKGTKLVLEQVVTSIASVADT 540
Query: 541 AEEKFVPYYDLFMPSLKHIVENAVQKELRLLRGKTIECISLIGLAVGKEKFMQDASDVMQ 600
AEEKFVPYYDLFMPSLKHIVENAVQKELRLLRGKTIECISLIGLAVGKEKFMQDASDVMQ
Sbjct: 541 AEEKFVPYYDLFMPSLKHIVENAVQKELRLLRGKTIECISLIGLAVGKEKFMQDASDVMQ 600
Query: 601 LLLKTQTDFNDMEDDDPQISYMISAWARMCKILGKEFQQYLPVVMGPLMKTASIKPEVAL 660
LLLKTQTDFNDMEDDDPQISYMISAWARMCKILGKEFQQYLPVVMGPLMKTASIKPEVAL
Sbjct: 601 LLLKTQTDFNDMEDDDPQISYMISAWARMCKILGKEFQQYLPVVMGPLMKTASIKPEVAL 660
Query: 661 LDTQDMENMSDDDGWEFVNLGDQQSFGIKTAGLEEKSTACQMLVCYAKELKEGFVEYTEQ 720
LDTQDMENMSDDDGWEFVNLGDQQSFGIKTAGLEEKSTACQMLVCYAKELKEGFVEYTEQ
Sbjct: 661 LDTQDMENMSDDDGWEFVNLGDQQSFGIKTAGLEEKSTACQMLVCYAKELKEGFVEYTEQ 720
Query: 721 VVKLMVPLLKFYFHDGVRVAAAESMPLLLECARVRGPEYLTQMWHFMCDALIKAIGTEPD 780
VVKLMVPLLKFYFHDGVRVAAAESMPLLLECARVRGPEYLTQMWHFMCDALIKAIGTEPD
Sbjct: 721 VVKLMVPLLKFYFHDGVRVAAAESMPLLLECARVRGPEYLTQMWHFMCDALIKAIGTEPD 780
Query: 781 SDVLSEIMHSFAKCIEVMGDGCLNNEHFEELGGILKAKLEEHFKNQELRQVKRQDEDYDE 840
SDVLSEIMHSFAKCIEVMGDGCLNNEHFEELGGILKAKLEEHFKNQELRQVKRQDEDYDE
Sbjct: 781 SDVLSEIMHSFAKCIEVMGDGCLNNEHFEELGGILKAKLEEHFKNQELRQVKRQDEDYDE 840
Query: 841 QVEESLQDEDDNDVYILTKVSDILHSIFSSYKEKVLPWFEQLLPLIVNLICPHRPWPDRQ 900
QVEESLQDEDDNDVYILTKVSDILHSIFSSYKEKVLPWFEQLLPLIVNLICPHRPWPDRQ
Sbjct: 841 QVEESLQDEDDNDVYILTKVSDILHSIFSSYKEKVLPWFEQLLPLIVNLICPHRPWPDRQ 900
Query: 901 WGLCIFDDVIEHCSPASFKYAEYFLRPMLQYVCDNSPEVRQAAAYGLGVMAQYGGDNYRP 960
WGLCIFDDVIEHCSPASFKYAEYFLRPMLQYVCDNSPEVRQAAAYGLGVMAQYGGDNYRP
Sbjct: 901 WGLCIFDDVIEHCSPASFKYAEYFLRPMLQYVCDNSPEVRQAAAYGLGVMAQYGGDNYRP 960
Query: 961 FCTEALPLLVRVIQSADSKTKENVNATENCISAVGKIMKFKPDCVNVEEVLPHWLSWLPL 1020
FCTEALPLLVRVIQSADSKTKENVNATENCISAVGKIMKFKPDCVNVEEVLPHWLSWLPL
Sbjct: 961 FCTEALPLLVRVIQSADSKTKENVNATENCISAVGKIMKFKPDCVNVEEVLPHWLSWLPL 1020
Query: 1021 HEDKEEAVQTFNYLCDLIESNHPIVLGPNNTNLPKIFSIIAEGEMHEAIKHEDPCAKRLA 1080
HEDKEEAVQTFNYLCDLIESNHPIVLGPNNTNLPKIFSIIAEGEMHEAIKHEDPCAKRLA
Sbjct: 1021 HEDKEEAVQTFNYLCDLIESNHPIVLGPNNTNLPKIFSIIAEGEMHEAIKHEDPCAKRLA 1080
Query: 1081 NVVRQVQTSGGLWTECIAQLSPEQQAAIQELLNSA 1115
NVVRQVQTSGGLWTECIAQLSPEQQAAIQELLNSA
Sbjct: 1081 NVVRQVQTSGGLWTECIAQLSPEQQAAIQELLNSA 1115
>gi|45331213 RAN binding protein 6 [Homo sapiens]
Length = 1105
Score = 1788 bits (4630), Expect = 0.0
Identities = 869/1099 (79%), Positives = 992/1099 (90%)
Query: 17 SAMAAAAAEQQQFYLLLGNLLSPDNVVRKQAEETYENIPGQSKITFLLQAIRNTTAAEEA 76
+ + A +E+Q+FY LL NL++P +VR+QAEE YENIPG K TFLL A+RN A E
Sbjct: 7 AGVPATVSEKQEFYQLLKNLINPSCMVRRQAEEIYENIPGLCKTTFLLDAVRNRRAGYEV 66
Query: 77 RQMAAVLLRRLLSSAFDEVYPALPSDVQTAIKSELLMIIQMETQSSMRKKVCDIAAELAR 136
RQMAA LLRRLLSS F+EVYP LP+DVQ +K EL++ +++ET +SMRKK+CDI A LAR
Sbjct: 67 RQMAAALLRRLLSSGFEEVYPNLPADVQRDVKIELILAVKLETHASMRKKLCDIFAVLAR 126
Query: 137 NLIDEDGNNQWPEGLKFLFDSVSSQNVGLREAALHIFWNFPGIFGNQQQHYLDVIKRMLV 196
NLIDEDG N WPEGLKFL DS+ S+NV L E ALH+FW+FPGIFG Q++H LD+IKR+L
Sbjct: 127 NLIDEDGTNHWPEGLKFLIDSIYSKNVVLWEVALHVFWHFPGIFGTQERHDLDIIKRLLD 186
Query: 197 QCMQDQEHPSIRTLSARATAAFILANEHNVALFKHFADLLPGFLQAVNDSCYQNDDSVLK 256
QC+QDQEHP+IRTLSARA AAF+LANE+N+ALFK FADLLPG LQAVNDSCYQ+DDSVL+
Sbjct: 187 QCIQDQEHPAIRTLSARAAAAFVLANENNIALFKDFADLLPGILQAVNDSCYQDDDSVLE 246
Query: 257 SLVEIADTVPKYLRPHLEATLQLSLKLCGDTSLNNMQRQLALEVIVTLSETAAAMLRKHT 316
SLVEIADTVPKYL P+LE TLQLSLKLCGD+ L+N+QRQLALEVIVTLSETA ML+KHT
Sbjct: 247 SLVEIADTVPKYLGPYLEDTLQLSLKLCGDSRLSNLQRQLALEVIVTLSETATPMLKKHT 306
Query: 317 NIVAQTIPQMLAMMVDLEEDEDWANADELEDDDFDSNAVAGESALDRMACGLGGKLVLPM 376
NI+AQ +P +LAMMVDL++DEDW NADE+E+DDFDSNAVA ESALDR+ACGLGGK+VLPM
Sbjct: 307 NIIAQAVPHILAMMVDLQDDEDWVNADEMEEDDFDSNAVAAESALDRLACGLGGKVVLPM 366
Query: 377 IKEHIMQMLQNPDWKYRHAGLMALSAIGEGCHQQMEGILNEIVNFVLLFLQDPHPRVRYA 436
KEHIMQMLQ+PDWKYRHAGLMALSAIGEGCHQQME IL+E VN VLLFLQDPHPRVR A
Sbjct: 367 TKEHIMQMLQSPDWKYRHAGLMALSAIGEGCHQQMESILDETVNSVLLFLQDPHPRVRAA 426
Query: 437 ACNAVGQMATDFAPGFQKKFHEKVIAALLQTMEDQGNQRVQAHAAAALINFTEDCPKSLL 496
AC +GQMATDFAP FQKKFHE VIAALL+TME+QGNQRVQ+HAA+ALI F EDCPKSLL
Sbjct: 427 ACTTLGQMATDFAPNFQKKFHETVIAALLRTMENQGNQRVQSHAASALIIFIEDCPKSLL 486
Query: 497 IPYLDNLVKHLHSIMVLKLQELIQKGTKLVLEQVVTSIASVADTAEEKFVPYYDLFMPSL 556
+ Y+D++VK+LHS++V+KLQELI+ GTKL LEQ+VT+IASVADT EEKFVPYYD+FMPSL
Sbjct: 487 VLYVDSMVKNLHSVLVIKLQELIRNGTKLALEQLVTTIASVADTIEEKFVPYYDIFMPSL 546
Query: 557 KHIVENAVQKELRLLRGKTIECISLIGLAVGKEKFMQDASDVMQLLLKTQTDFNDMEDDD 616
KHIVE AVQKEL+LLRGKTIECIS IGLAVGKEKFMQDAS+VMQLLLKTQ+D N+MEDDD
Sbjct: 547 KHIVELAVQKELKLLRGKTIECISHIGLAVGKEKFMQDASNVMQLLLKTQSDLNNMEDDD 606
Query: 617 PQISYMISAWARMCKILGKEFQQYLPVVMGPLMKTASIKPEVALLDTQDMENMSDDDGWE 676
PQ SYM+SAWARMCKILGK+FQQYLP+V+ PL+KTAS KP+VALLDTQD+ENMSDDDGW+
Sbjct: 607 PQTSYMVSAWARMCKILGKDFQQYLPLVIEPLIKTASAKPDVALLDTQDVENMSDDDGWQ 666
Query: 677 FVNLGDQQSFGIKTAGLEEKSTACQMLVCYAKELKEGFVEYTEQVVKLMVPLLKFYFHDG 736
FVNLGDQQSFGIKT+GLE K+TACQMLV YAKEL+EGFVEYTEQVVKLMVPLLKFYFHD
Sbjct: 667 FVNLGDQQSFGIKTSGLEAKATACQMLVYYAKELREGFVEYTEQVVKLMVPLLKFYFHDN 726
Query: 737 VRVAAAESMPLLLECARVRGPEYLTQMWHFMCDALIKAIGTEPDSDVLSEIMHSFAKCIE 796
VRVAAAESMP LLECAR+RGPEYL QMW F+CD LIKAIGTEPD+DVLSEIM+SFAK IE
Sbjct: 727 VRVAAAESMPFLLECARIRGPEYLAQMWQFICDPLIKAIGTEPDTDVLSEIMNSFAKSIE 786
Query: 797 VMGDGCLNNEHFEELGGILKAKLEEHFKNQELRQVKRQDEDYDEQVEESLQDEDDNDVYI 856
VMGDGCLN+EH EELGGILKAKLE HFKNQELRQVKRQ+E+YD+QVE SLQDED+ DVYI
Sbjct: 787 VMGDGCLNDEHLEELGGILKAKLEGHFKNQELRQVKRQEENYDQQVEMSLQDEDECDVYI 846
Query: 857 LTKVSDILHSIFSSYKEKVLPWFEQLLPLIVNLICPHRPWPDRQWGLCIFDDVIEHCSPA 916
LTKVSDILHS+FS+YKEK+LPWFEQLLPLIVNLIC RPWPDRQWGLCIFDD+IEHCSP
Sbjct: 847 LTKVSDILHSLFSTYKEKILPWFEQLLPLIVNLICSSRPWPDRQWGLCIFDDIIEHCSPT 906
Query: 917 SFKYAEYFLRPMLQYVCDNSPEVRQAAAYGLGVMAQYGGDNYRPFCTEALPLLVRVIQSA 976
SFKY EYF PML + DN+PEVRQAAAYGLGVMAQ+GGD+YR C+EA+PLLV+VI+ A
Sbjct: 907 SFKYVEYFRWPMLLNMRDNNPEVRQAAAYGLGVMAQFGGDDYRSLCSEAVPLLVKVIKCA 966
Query: 977 DSKTKENVNATENCISAVGKIMKFKPDCVNVEEVLPHWLSWLPLHEDKEEAVQTFNYLCD 1036
+SKTK+NV ATENCISA+GKI+KFKP+CVNV+EVLPHWLSWLPLHEDKEEA+QT ++LCD
Sbjct: 967 NSKTKKNVIATENCISAIGKILKFKPNCVNVDEVLPHWLSWLPLHEDKEEAIQTLSFLCD 1026
Query: 1037 LIESNHPIVLGPNNTNLPKIFSIIAEGEMHEAIKHEDPCAKRLANVVRQVQTSGGLWTEC 1096
LIESNHP+V+GPNN+NLPKI SIIAEG+++E I +EDPCAKRLANVVRQVQTS LW EC
Sbjct: 1027 LIESNHPVVIGPNNSNLPKIISIIAEGKINETINYEDPCAKRLANVVRQVQTSEDLWLEC 1086
Query: 1097 IAQLSPEQQAAIQELLNSA 1115
++QL EQQ A+QELLN A
Sbjct: 1087 VSQLDDEQQEALQELLNFA 1105
>gi|62460637 importin 4 [Homo sapiens]
Length = 1081
Score = 167 bits (424), Expect = 4e-41
Identities = 238/1055 (22%), Positives = 445/1055 (42%), Gaps = 101/1055 (9%)
Query: 19 MAAAAAEQQQFYLLLGNLLSPDNVVRKQAEETYENIPGQSKITFLLQAIRNTTAAEEARQ 78
M +A EQ LL LL PD ++A E + + L + + A + RQ
Sbjct: 1 MESAGLEQ-----LLRELLLPDTERIRRATEQLQIVLRAPAALPALCDLLASAADPQIRQ 55
Query: 79 MAAVLLRRLLSSAFDEVYPALPSDVQTAIKSELLMIIQMETQSSMRKKVCDIAAELARNL 138
AAVL RR L++ + L ++ + ++KS +L +Q ET+ + + ++A + R
Sbjct: 56 FAAVLTRRRLNTRWRR----LAAEQRESLKSLILTALQRETEHCVSLSLAQLSATIFR-- 109
Query: 139 IDEDGNNQWPEGLKFLFDSVSSQNVGLREAALHIF----WNFPGIFGNQQQHYLDVIKRM 194
++G WP+ L+ L S S + RE L + + P F Q H+ +++ R+
Sbjct: 110 --KEGLEAWPQLLQLLQHSTHSPHSPEREMGLLLLSVVVTSRPEAF---QPHHRELL-RL 163
Query: 195 LVQCMQDQEHPSIRTLSARA--TAAFILANEHNVALFKHFADLLPGFLQAVNDSCYQNDD 252
L + + + P + S R T A L+ E +V L + L +Q +
Sbjct: 164 LNETLGEVGSPGLLFYSLRTLTTMAPYLSTE-DVPLARMLVPKLIMAMQTLIPIDEAKAC 222
Query: 253 SVLKSLVEIADTVPKYLRPHLEATLQLSLKLCGDTSLNNMQRQLALEVIVTLSETAAAML 312
L++L E+ ++ + P+L L L++ + +L N R L + L + + L
Sbjct: 223 EALEALDELLESEVPVITPYLSEVLTFCLEVARNVALGNAIRIRILCCLTFLVKVKSKAL 282
Query: 313 RKHTNIVAQTIPQMLAMMVDLEEDEDWANADELEDDDFDSNAVAGE-----------SAL 361
K+ + +P +L + + E + ED D + + E +
Sbjct: 283 LKN-----RLLPPLLHTLFPIVAAEPPPGQLDPEDQDSEEEELEIELMGETPKHFAVQVV 337
Query: 362 DRMACGLGGKLVLPMIKEHIMQMLQNPDWKYRHAGLMALSAIGEGCHQQM-EGILNEIVN 420
D +A L + + P + + + L++ R AGL+ L+ + +G + + +L ++
Sbjct: 338 DMLALHLPPEKLCPQLMPMLEEALRSESPYQRKAGLLVLAVLSDGAGDHIRQRLLPPLLQ 397
Query: 421 FVLLFLQDPHPRVRYAACNAVGQMATDFAPGFQKKFHEKVIAALLQTMEDQ--GNQRVQA 478
V L+DP VR AA A+GQ + + P + +V+ LL ++ G+ A
Sbjct: 398 IVCKGLEDPSQVVRNAALFALGQFSENLQPHISS-YSREVMPLLLAYLKSVPLGHTHHLA 456
Query: 479 HAAAALINFTEDC-PKSLLIPYLDNLVKHLHSIMVLKLQELIQKGTKLVLEQVVTSIASV 537
A AL NF E+ PK + PYL L++ + LQ L + E V+++ ++
Sbjct: 457 KACYALENFVENLGPK--VQPYLPELMECM-------LQLLRNPSSPRAKELAVSALGAI 507
Query: 538 ADTAEEKFVPYYDLFMPSLKHIVENAVQKELRLLRGKTIECISLIGLAVGKEKFMQDASD 597
A A+ +PY+ M L+ + +++L+ ++ +++E + ++ AVG E A +
Sbjct: 508 ATAAQASLLPYFPAIMEHLREFLLTG-REDLQPVQIQSLETLGVLARAVG-EPMRPLAEE 565
Query: 598 VMQLLLKTQTDFNDMEDDDPQISYMISAWARMCKILGK----EFQQYLPVVMGPLMKTAS 653
QL L D DD S +A + ++G+ +Q +++ L T
Sbjct: 566 CCQLGL----GLCDQVDDPDLRRCTYSLFAALSGLMGEGLAPHLEQITTLMLLSLRSTEG 621
Query: 654 IKPEVA-----LL-----DTQDMENMSDDDGWEFVNLGDQQSFGIKTAGLEEKSTACQML 703
I P+ LL D ++ E + D+D E + + + ++ A +EK C +
Sbjct: 622 IVPQYDGSSSFLLFDDESDGEEEEELMDEDVEEEDD-SEISGYSVENAFFDEKEDTCAAV 680
Query: 704 VCYAKELKEGFVEYTEQVVKLMVPLLKFYFHDGVRVAAAESMPLLL--------ECARVR 755
+ F+ Y E V + + LL+ H VR AA E++ C
Sbjct: 681 GEISVNTSVAFLPYMESVFEEVFKLLECP-HLNVRKAAHEALGQFCCALHKACQSCPSEP 739
Query: 756 GPEYLTQMWHFMCDALIKAIGTEPDSDVLSEIMHSFAKCIEVMGDGCLNNE-HFEELGGI 814
L + + ++A+ E + V+ ++ + + G L EL G+
Sbjct: 740 NTAALQAALARVVPSYMQAVNRERERQVVMAVLEALTGVLRSCGTLTLKPPGRLAELCGV 799
Query: 815 LKAKLEEHFKNQELRQVKRQDEDYDEQVEESLQDEDDNDVYILTKVSDILHSIFSSYK-E 873
LKA L+ K +D DE+ EE D+ + D +L + + ++ ++ +
Sbjct: 800 LKAVLQR----------KTACQDTDEEEEEEDDDQAEYDAMLLEHAGEAIPALAAAAGGD 849
Query: 874 KVLPWFEQLLPLIVNLICPHRPWPDRQWGLCIFDDVIEHCSPASFKYAEYFLRPMLQYVC 933
P+F LPL+V ++ + + + I+ AS ++ L +L
Sbjct: 850 SFAPFFAGFLPLLVCKTKQGCTVAEKSFAVGTLAETIQGLGAASAQFVSRLLPVLLSTAQ 909
Query: 934 DNSPEVRQAAAYGLGVMAQYGGDNYRPFCTEALPLLVRVIQSADSKTKENVNATENCISA 993
+ PEVR A +G+GV+A++GG + + L LL ++ + + +N A
Sbjct: 910 EADPEVRSNAIFGMGVLAEHGGHPAQEHFPKLLGLLFPLL-----ARERHDRVRDNICGA 964
Query: 994 VGKIMKFKPDCVNVEEVLPHWLSWLPLHEDKEEAV 1028
+ +++ P +VL L LPL ED EE V
Sbjct: 965 LARLLMASPTRKPEPQVLAALLHALPLKEDLEEWV 999
>gi|23510381 transportin 1 isoform 2 [Homo sapiens]
Length = 890
Score = 76.6 bits (187), Expect = 1e-13
Identities = 149/673 (22%), Positives = 271/673 (40%), Gaps = 115/673 (17%)
Query: 27 QQFYLLLGNLLSPDNVVRKQAEETYENIPG----QSKITFLLQAIRNTTAAEEARQMAAV 82
QQ LL SPD +++ ++ E + + + F+L +++ E R ++ +
Sbjct: 13 QQILQLLKESQSPDTTIQRTVQQKLEQLNQYPDFNNYLIFVLTKLKSED--EPTRSLSGL 70
Query: 83 LLRRLLSSAFDEVYPALPSDVQTAIKSELLMIIQMETQSSMRKKVCDIAAELARNLIDED 142
+L+ + + F P+ V IKSE L I ++ +R V + +A +
Sbjct: 71 ILKNNVKAHFQN----FPNGVTDFIKSECLNNIG-DSSPLIRATVGILITTIA----SKG 121
Query: 143 GNNQWPEGLKFLFDSVSSQNVGLREAALHIFWNFPGIFGNQQQHY-LDVIKR----MLVQ 197
WP+ L L + S++ E A F I + + DV+ R M+ +
Sbjct: 122 ELQNWPDLLPKLCSLLDSEDYNTCEGA---FGALQKICEDSAEILDSDVLDRPLNIMIPK 178
Query: 198 CMQDQEH--PSIRTLSARATAAFILANEHNVALFKHFADLLPGFLQAVNDSCYQNDDSVL 255
+Q +H P IR+ + FI++ AL H + D + +V
Sbjct: 179 FLQFFKHSSPKIRSHAVACVNQFIISRTQ--ALMLHIDSFIENLFALAGDEEPEVRKNVC 236
Query: 256 KSLVEIADTVPKYLRPHLEATLQLSLKLCGDTSLNNMQRQLALEVIVTLSETAAAMLRKH 315
++LV + + L PH+ ++ L+ D N A E +TL+E
Sbjct: 237 RALVMLLEVRMDRLLPHMHNIVEYMLQRTQDQDENVALE--ACEFWLTLAEQPICK---- 290
Query: 316 TNIVAQTIPQMLAMMV---------------DLEEDEDWANA------------------ 342
+++ + +P+++ ++V D+EEDE ++
Sbjct: 291 -DVLVRHLPKLIPVLVNGMKYSDIDIILLKGDVEEDETIPDSEQDIRPRFHRSRTVAQQH 349
Query: 343 ------------DELEDDDFDSN---AVAGESALDRMACGLGGKL---VLPMIKEHIMQM 384
DE++DDD S+ +ALD +A +L +LP++KE +
Sbjct: 350 DEDGIEEEDDDDDEIDDDDTISDWNLRKCSAAALDVLANVYRDELLPHILPLLKE----L 405
Query: 385 LQNPDWKYRHAGLMALSAIGEGCHQQMEGILNEIVNFVLLFLQDPHPRVRYAACNAVGQM 444
L + +W + +G++ L AI EGC Q M L E++ ++ L D VR C + +
Sbjct: 406 LFHHEWVVKESGILVLGAIAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSITCWTLSRY 465
Query: 445 ATDFAPGFQKKFHEKVIAALLQTMEDQGNQRVQAHAAAALINFTED-CPKSLLIPYLDNL 503
A + + ++ LL+ + D N+RVQ A +A E+ C + L+PYL
Sbjct: 466 AHWVVSQPPDTYLKPLMTELLKRILD-SNKRVQEAACSAFATLEEEACTE--LVPYL--- 519
Query: 504 VKHLHSIMVLKLQELIQKGTKLVLEQVVTSIASVADTAEEKFVPYYDLFMPSL--KHIVE 561
++ +V + K ++ + + T SV + Y + MP L K +
Sbjct: 520 -AYILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKP--EYIQMLMPPLIQKWNML 576
Query: 562 NAVQKELRLLRGKTIECISLIGLAVGKEKFMQDASDVMQ----LLLKT--QTDFNDMEDD 615
K+L L +EC+S + A+ + F+ V Q L+ KT Q N+ + D
Sbjct: 577 KDEDKDLFPL----LECLSSVATAL-QSGFLPYCEPVYQRCVNLVQKTLAQAMLNNAQPD 631
Query: 616 D---PQISYMISA 625
P +MI A
Sbjct: 632 QYEAPDKDFMIVA 644
>gi|133925811 transportin 1 isoform 1 [Homo sapiens]
Length = 898
Score = 76.6 bits (187), Expect = 1e-13
Identities = 149/673 (22%), Positives = 271/673 (40%), Gaps = 115/673 (17%)
Query: 27 QQFYLLLGNLLSPDNVVRKQAEETYENIPG----QSKITFLLQAIRNTTAAEEARQMAAV 82
QQ LL SPD +++ ++ E + + + F+L +++ E R ++ +
Sbjct: 21 QQILQLLKESQSPDTTIQRTVQQKLEQLNQYPDFNNYLIFVLTKLKSED--EPTRSLSGL 78
Query: 83 LLRRLLSSAFDEVYPALPSDVQTAIKSELLMIIQMETQSSMRKKVCDIAAELARNLIDED 142
+L+ + + F P+ V IKSE L I ++ +R V + +A +
Sbjct: 79 ILKNNVKAHFQN----FPNGVTDFIKSECLNNIG-DSSPLIRATVGILITTIA----SKG 129
Query: 143 GNNQWPEGLKFLFDSVSSQNVGLREAALHIFWNFPGIFGNQQQHY-LDVIKR----MLVQ 197
WP+ L L + S++ E A F I + + DV+ R M+ +
Sbjct: 130 ELQNWPDLLPKLCSLLDSEDYNTCEGA---FGALQKICEDSAEILDSDVLDRPLNIMIPK 186
Query: 198 CMQDQEH--PSIRTLSARATAAFILANEHNVALFKHFADLLPGFLQAVNDSCYQNDDSVL 255
+Q +H P IR+ + FI++ AL H + D + +V
Sbjct: 187 FLQFFKHSSPKIRSHAVACVNQFIISRTQ--ALMLHIDSFIENLFALAGDEEPEVRKNVC 244
Query: 256 KSLVEIADTVPKYLRPHLEATLQLSLKLCGDTSLNNMQRQLALEVIVTLSETAAAMLRKH 315
++LV + + L PH+ ++ L+ D N A E +TL+E
Sbjct: 245 RALVMLLEVRMDRLLPHMHNIVEYMLQRTQDQDENVALE--ACEFWLTLAEQPICK---- 298
Query: 316 TNIVAQTIPQMLAMMV---------------DLEEDEDWANA------------------ 342
+++ + +P+++ ++V D+EEDE ++
Sbjct: 299 -DVLVRHLPKLIPVLVNGMKYSDIDIILLKGDVEEDETIPDSEQDIRPRFHRSRTVAQQH 357
Query: 343 ------------DELEDDDFDSN---AVAGESALDRMACGLGGKL---VLPMIKEHIMQM 384
DE++DDD S+ +ALD +A +L +LP++KE +
Sbjct: 358 DEDGIEEEDDDDDEIDDDDTISDWNLRKCSAAALDVLANVYRDELLPHILPLLKE----L 413
Query: 385 LQNPDWKYRHAGLMALSAIGEGCHQQMEGILNEIVNFVLLFLQDPHPRVRYAACNAVGQM 444
L + +W + +G++ L AI EGC Q M L E++ ++ L D VR C + +
Sbjct: 414 LFHHEWVVKESGILVLGAIAEGCMQGMIPYLPELIPHLIQCLSDKKALVRSITCWTLSRY 473
Query: 445 ATDFAPGFQKKFHEKVIAALLQTMEDQGNQRVQAHAAAALINFTED-CPKSLLIPYLDNL 503
A + + ++ LL+ + D N+RVQ A +A E+ C + L+PYL
Sbjct: 474 AHWVVSQPPDTYLKPLMTELLKRILD-SNKRVQEAACSAFATLEEEACTE--LVPYL--- 527
Query: 504 VKHLHSIMVLKLQELIQKGTKLVLEQVVTSIASVADTAEEKFVPYYDLFMPSL--KHIVE 561
++ +V + K ++ + + T SV + Y + MP L K +
Sbjct: 528 -AYILDTLVFAFSKYQHKNLLILYDAIGTLADSVGHHLNKP--EYIQMLMPPLIQKWNML 584
Query: 562 NAVQKELRLLRGKTIECISLIGLAVGKEKFMQDASDVMQ----LLLKT--QTDFNDMEDD 615
K+L L +EC+S + A+ + F+ V Q L+ KT Q N+ + D
Sbjct: 585 KDEDKDLFPL----LECLSSVATAL-QSGFLPYCEPVYQRCVNLVQKTLAQAMLNNAQPD 639
Query: 616 D---PQISYMISA 625
P +MI A
Sbjct: 640 QYEAPDKDFMIVA 652
>gi|19923142 karyopherin beta 1 [Homo sapiens]
Length = 876
Score = 68.6 bits (166), Expect = 3e-11
Identities = 109/479 (22%), Positives = 208/479 (43%), Gaps = 70/479 (14%)
Query: 32 LLGNLLSPDNVVRKQAEETYENIPGQSKITFLLQAIR---NTTAAEEARQMAAVLLRRLL 88
+L +SPD + + A++ E ++ TFL++ R N ++ AR A + ++ L
Sbjct: 6 ILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQIKNSL 65
Query: 89 SSA-------FDEVYPALPSDVQTAIKSELLMIIQMETQSSMRKKVCDIAAELARNLIDE 141
+S + + + A+ ++ + +K+ +L + ET C A +
Sbjct: 66 TSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAEIPV-- 123
Query: 142 DGNNQWPEGLKFLFDSVSSQNVG--LREAALH-IFWNFPGIFGNQQQHYLDVIKRMLVQC 198
NQWPE + L +V++ N ++E+ L I + I Q Q + I ++Q
Sbjct: 124 ---NQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQG 180
Query: 199 MQDQEHPSIRTLSARATAAFILANEHNVALF-----KHFADLLPGFLQAVNDSCYQNDDS 253
M+ +E PS + AT A + + E A F +HF +Q V ++ D
Sbjct: 181 MRKEE-PS-NNVKLAATNALLNSLEFTKANFDKESERHF------IMQVVCEATQCPDTR 232
Query: 254 V----LKSLVEIADTVPKYLRPHL-----EATLQLSLKLCGDTSLNNMQR-----QLALE 299
V L++LV+I +Y+ ++ T++ + +L ++ ++
Sbjct: 233 VRVAALQNLVKIMSLYYQYMETYMGPALFAITIEAMKSDIDEVALQGIEFWSNVCDEEMD 292
Query: 300 VIVTLSETAA-AMLRKHTN------IVAQTIPQMLAMMVDLEEDEDWANADELEDDDFDS 352
+ + SE A +HT+ + +P + + +E++D DDD++
Sbjct: 293 LAIEASEAAEQGRPPEHTSKFYAKGALQYLVPILTQTLTKQDENDD--------DDDWNP 344
Query: 353 NAVAGESALDRMACGLGGKL--VLPMIKEHIMQMLQNPDWKYRHAGLMALSAIGEGCH-Q 409
AG + C + VLP IKEHI +NPDW+YR A +MA I EG
Sbjct: 345 CKAAGVCLMLLATCCEDDIVPHVLPFIKEHI----KNPDWRYRDAAVMAFGCILEGPEPS 400
Query: 410 QMEGILNEIVNFVLLFLQDPHPRVRYAACNAVGQMATDFAPGFQKKFHEKVIAALLQTM 468
Q++ ++ + + ++ ++DP VR A VG++ + P + ++ +A LLQ +
Sbjct: 401 QLKPLVIQAMPTLIELMKDPSVVVRDTAAWTVGRIC-ELLP--EAAINDVYLAPLLQCL 456
Score = 45.4 bits (106), Expect = 3e-04
Identities = 41/191 (21%), Positives = 87/191 (45%), Gaps = 27/191 (14%)
Query: 493 KSLLIPYLDNLVKHLHSIMVLKLQELIQK----------GTKLVLEQVVTSIASVADTAE 542
+SLL L N+++ + L++ +++ G+ V E + +++++ +
Sbjct: 581 QSLLCATLQNVLRKVQHQDALQISDVVMASLLRMFQSTAGSGGVQEDALMAVSTLVEVLG 640
Query: 543 EKFVPYYDLFMPSLKHIVENAVQKELRLLRGKTIECISLIGLAVGKEKFMQD-----ASD 597
+F+ Y + F P L ++N + ++ C++ +GL + +Q +
Sbjct: 641 GEFLKYMEAFKPFLGIGLKNYAEYQV---------CLAAVGLVGDLCRALQSNIIPFCDE 691
Query: 598 VMQLLLKTQTDFNDMEDDDPQISYMISAWARMCKILGKEFQQYLPVVMGPLMKTASIKPE 657
VMQLLL+ + N PQI +S + + +G EF++YL VV+ L + + + +
Sbjct: 692 VMQLLLENLGNENVHRSVKPQI---LSVFGDIALAIGGEFKKYLEVVLNTLQQASQAQVD 748
Query: 658 VALLDTQDMEN 668
+ D D N
Sbjct: 749 KSDYDMVDYLN 759
>gi|209969838 transportin 2 (importin 3, karyopherin beta 2b)
isoform 1 [Homo sapiens]
Length = 897
Score = 67.4 bits (163), Expect = 7e-11
Identities = 132/616 (21%), Positives = 243/616 (39%), Gaps = 88/616 (14%)
Query: 27 QQFYLLLGNLLSPDNVVRKQAEETYENIPG----QSKITFLLQAIRNTTAAEEARQMAAV 82
QQ LL + SP+ ++ ++ + + + + F+L +++ E R ++ +
Sbjct: 11 QQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSED--EPTRSLSGL 68
Query: 83 LLRRLLSSAFDEVYPALPSDVQTAIKSELLMIIQMETQSSMRKKVCDIAAELARNLIDED 142
+L+ + + Y + P V IK E L I SS+ + I L + +
Sbjct: 69 ILKNNVKAH----YQSFPPPVADFIKQECLNNIG--DASSLIRATIGI---LITTIASKG 119
Query: 143 GNNQWPEGLKFLFDSVSSQNVGLREAALHIFWNFPGIFGNQQQHYLDVIKR----MLVQC 198
WPE L L + ++S++ E A + + D + R M+ +
Sbjct: 120 ELQMWPELLPQLCNLLNSEDYNTCEGAFGALQKI--CEDSSELLDSDALNRPLNIMIPKF 177
Query: 199 MQDQEH--PSIRTLSARATAAFILANEHNVALFKHFADLLPGFLQAVNDSCYQNDDSVLK 256
+Q +H P IR+ + FI+ + AL + + D + +V +
Sbjct: 178 LQFFKHCSPKIRSHAIACVNQFIM--DRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCR 235
Query: 257 SLVEIADTVPKYLRPHLEATLQLSLKLCGDTSLNNMQRQLALEVIVTLSETAAA--MLRK 314
+LV + + L PH+ + +Q L+ D N A E +TL+E +L
Sbjct: 236 ALVMLLEVRIDRLIPHMHSIIQYMLQRTQDHDENVALE--ACEFWLTLAEQPICKEVLAS 293
Query: 315 HTNIVAQTIP-----------QMLAMMVDLEEDE-------------------------D 338
H + Q IP ++ + D+EEDE +
Sbjct: 294 H---LVQLIPILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAE 350
Query: 339 WANADELEDDDFDSNAVA-------GESALDRMACGLGGKLVLPMIKEHIMQMLQNPDWK 391
+ E +DD D +A++ +ALD +A +L LP + + +L +P+W
Sbjct: 351 RPDGSEDAEDDDDDDALSDWNLRKCSAAALDVLANVFREEL-LPHLLPLLKGLLFHPEWV 409
Query: 392 YRHAGLMALSAIGEGCHQQMEGILNEIVNFVLLFLQDPHPRVRYAACNAVGQMATDFAPG 451
+ +G++ L AI EGC Q M L E++ ++ L D VR AC + + A
Sbjct: 410 VKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQ 469
Query: 452 FQKKFHEKVIAALLQTMEDQGNQRVQAHAAAALINFTED-CPKSLLIPYLDNLVKHLHSI 510
+ ++ LL+ + D GN+RVQ A +A E+ C + L+PYL ++
Sbjct: 470 PPDMHLKPLMTELLKRILD-GNKRVQEAACSAFATLEEEACTE--LVPYL----SYILDT 522
Query: 511 MVLKLQELIQKGTKLVLEQVVTSIASVADTAEEKFVPYYDLFMPSLKHIVENAVQKELRL 570
+V + K ++ + + T SV + Y MP L ++ L
Sbjct: 523 LVFAFGKYQHKNLLILYDAIGTLADSVGHHLNQP--EYIQKLMPPLIQKWNELKDEDKDL 580
Query: 571 LRGKTIECISLIGLAV 586
+EC+S + A+
Sbjct: 581 F--PLLECLSSVATAL 594
>gi|209969836 transportin 2 (importin 3, karyopherin beta 2b)
isoform 3 [Homo sapiens]
Length = 887
Score = 67.4 bits (163), Expect = 7e-11
Identities = 132/616 (21%), Positives = 243/616 (39%), Gaps = 88/616 (14%)
Query: 27 QQFYLLLGNLLSPDNVVRKQAEETYENIPG----QSKITFLLQAIRNTTAAEEARQMAAV 82
QQ LL + SP+ ++ ++ + + + + F+L +++ E R ++ +
Sbjct: 11 QQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSED--EPTRSLSGL 68
Query: 83 LLRRLLSSAFDEVYPALPSDVQTAIKSELLMIIQMETQSSMRKKVCDIAAELARNLIDED 142
+L+ + + Y + P V IK E L I SS+ + I L + +
Sbjct: 69 ILKNNVKAH----YQSFPPPVADFIKQECLNNIG--DASSLIRATIGI---LITTIASKG 119
Query: 143 GNNQWPEGLKFLFDSVSSQNVGLREAALHIFWNFPGIFGNQQQHYLDVIKR----MLVQC 198
WPE L L + ++S++ E A + + D + R M+ +
Sbjct: 120 ELQMWPELLPQLCNLLNSEDYNTCEGAFGALQKI--CEDSSELLDSDALNRPLNIMIPKF 177
Query: 199 MQDQEH--PSIRTLSARATAAFILANEHNVALFKHFADLLPGFLQAVNDSCYQNDDSVLK 256
+Q +H P IR+ + FI+ + AL + + D + +V +
Sbjct: 178 LQFFKHCSPKIRSHAIACVNQFIM--DRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCR 235
Query: 257 SLVEIADTVPKYLRPHLEATLQLSLKLCGDTSLNNMQRQLALEVIVTLSETAAA--MLRK 314
+LV + + L PH+ + +Q L+ D N A E +TL+E +L
Sbjct: 236 ALVMLLEVRIDRLIPHMHSIIQYMLQRTQDHDENVALE--ACEFWLTLAEQPICKEVLAS 293
Query: 315 HTNIVAQTIP-----------QMLAMMVDLEEDE-------------------------D 338
H + Q IP ++ + D+EEDE +
Sbjct: 294 H---LVQLIPILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAE 350
Query: 339 WANADELEDDDFDSNAVA-------GESALDRMACGLGGKLVLPMIKEHIMQMLQNPDWK 391
+ E +DD D +A++ +ALD +A +L LP + + +L +P+W
Sbjct: 351 RPDGSEDAEDDDDDDALSDWNLRKCSAAALDVLANVFREEL-LPHLLPLLKGLLFHPEWV 409
Query: 392 YRHAGLMALSAIGEGCHQQMEGILNEIVNFVLLFLQDPHPRVRYAACNAVGQMATDFAPG 451
+ +G++ L AI EGC Q M L E++ ++ L D VR AC + + A
Sbjct: 410 VKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQ 469
Query: 452 FQKKFHEKVIAALLQTMEDQGNQRVQAHAAAALINFTED-CPKSLLIPYLDNLVKHLHSI 510
+ ++ LL+ + D GN+RVQ A +A E+ C + L+PYL ++
Sbjct: 470 PPDMHLKPLMTELLKRILD-GNKRVQEAACSAFATLEEEACTE--LVPYL----SYILDT 522
Query: 511 MVLKLQELIQKGTKLVLEQVVTSIASVADTAEEKFVPYYDLFMPSLKHIVENAVQKELRL 570
+V + K ++ + + T SV + Y MP L ++ L
Sbjct: 523 LVFAFGKYQHKNLLILYDAIGTLADSVGHHLNQP--EYIQKLMPPLIQKWNELKDEDKDL 580
Query: 571 LRGKTIECISLIGLAV 586
+EC+S + A+
Sbjct: 581 F--PLLECLSSVATAL 594
>gi|48675813 transportin 2 (importin 3, karyopherin beta 2b) isoform
2 [Homo sapiens]
Length = 887
Score = 67.4 bits (163), Expect = 7e-11
Identities = 132/616 (21%), Positives = 243/616 (39%), Gaps = 88/616 (14%)
Query: 27 QQFYLLLGNLLSPDNVVRKQAEETYENIPG----QSKITFLLQAIRNTTAAEEARQMAAV 82
QQ LL + SP+ ++ ++ + + + + F+L +++ E R ++ +
Sbjct: 11 QQVLQLLKDSQSPNTATQRIVQDKLKQLNQFPDFNNYLIFVLTRLKSED--EPTRSLSGL 68
Query: 83 LLRRLLSSAFDEVYPALPSDVQTAIKSELLMIIQMETQSSMRKKVCDIAAELARNLIDED 142
+L+ + + Y + P V IK E L I SS+ + I L + +
Sbjct: 69 ILKNNVKAH----YQSFPPPVADFIKQECLNNIG--DASSLIRATIGI---LITTIASKG 119
Query: 143 GNNQWPEGLKFLFDSVSSQNVGLREAALHIFWNFPGIFGNQQQHYLDVIKR----MLVQC 198
WPE L L + ++S++ E A + + D + R M+ +
Sbjct: 120 ELQMWPELLPQLCNLLNSEDYNTCEGAFGALQKI--CEDSSELLDSDALNRPLNIMIPKF 177
Query: 199 MQDQEH--PSIRTLSARATAAFILANEHNVALFKHFADLLPGFLQAVNDSCYQNDDSVLK 256
+Q +H P IR+ + FI+ + AL + + D + +V +
Sbjct: 178 LQFFKHCSPKIRSHAIACVNQFIM--DRAQALMDNIDTFIEHLFALAVDDDPEVRKNVCR 235
Query: 257 SLVEIADTVPKYLRPHLEATLQLSLKLCGDTSLNNMQRQLALEVIVTLSETAAA--MLRK 314
+LV + + L PH+ + +Q L+ D N A E +TL+E +L
Sbjct: 236 ALVMLLEVRIDRLIPHMHSIIQYMLQRTQDHDENVALE--ACEFWLTLAEQPICKEVLAS 293
Query: 315 HTNIVAQTIP-----------QMLAMMVDLEEDE-------------------------D 338
H + Q IP ++ + D+EEDE +
Sbjct: 294 H---LVQLIPILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKPRFHKSRTVTLPHEAE 350
Query: 339 WANADELEDDDFDSNAVA-------GESALDRMACGLGGKLVLPMIKEHIMQMLQNPDWK 391
+ E +DD D +A++ +ALD +A +L LP + + +L +P+W
Sbjct: 351 RPDGSEDAEDDDDDDALSDWNLRKCSAAALDVLANVFREEL-LPHLLPLLKGLLFHPEWV 409
Query: 392 YRHAGLMALSAIGEGCHQQMEGILNEIVNFVLLFLQDPHPRVRYAACNAVGQMATDFAPG 451
+ +G++ L AI EGC Q M L E++ ++ L D VR AC + + A
Sbjct: 410 VKESGILVLGAIAEGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQ 469
Query: 452 FQKKFHEKVIAALLQTMEDQGNQRVQAHAAAALINFTED-CPKSLLIPYLDNLVKHLHSI 510
+ ++ LL+ + D GN+RVQ A +A E+ C + L+PYL ++
Sbjct: 470 PPDMHLKPLMTELLKRILD-GNKRVQEAACSAFATLEEEACTE--LVPYL----SYILDT 522
Query: 511 MVLKLQELIQKGTKLVLEQVVTSIASVADTAEEKFVPYYDLFMPSLKHIVENAVQKELRL 570
+V + K ++ + + T SV + Y MP L ++ L
Sbjct: 523 LVFAFGKYQHKNLLILYDAIGTLADSVGHHLNQP--EYIQKLMPPLIQKWNELKDEDKDL 580
Query: 571 LRGKTIECISLIGLAV 586
+EC+S + A+
Sbjct: 581 F--PLLECLSSVATAL 594
>gi|54112117 splicing factor 3b, subunit 1 isoform 1 [Homo sapiens]
Length = 1304
Score = 38.1 bits (87), Expect = 0.047
Identities = 71/353 (20%), Positives = 137/353 (38%), Gaps = 62/353 (17%)
Query: 348 DDFDSNAVAGESALDRMACGLGGKLVLPMIKEHIMQMLQNPDWKYRHAGLMALS--AIGE 405
D++ N A A+ +A LG +LP +K W+ RH G+ + AI
Sbjct: 621 DEYVRNTTARAFAV--VASALGIPSLLPFLKAVCKS---KKSWQARHTGIKIVQQIAILM 675
Query: 406 GCHQQMEGILNEIVNFVLLFLQDPHPRVRYAACNAVGQMATDFAPGFQKKFHEKVIAALL 465
GC + L +V + L D +VR + A+ +A P + F + V+ L
Sbjct: 676 GC--AILPHLRSLVEIIEHGLVDEQQKVRTISALAIAALAEAATPYGIESF-DSVLKPLW 732
Query: 466 QTMEDQGNQRVQAHAAAALINFTEDCPKSLLIPYLDNLVKHLHS-----IMVLKLQELIQ 520
+ + + + A A LIP +D + ++ I++ + Q +
Sbjct: 733 KGIRQHRGKGLAAFLKAI----------GYLIPLMDAEYANYYTREVMLILIREFQSPDE 782
Query: 521 KGTKLVLEQVVTSIASVADTAEEKFVPYYDLFMPSLKHIVENAV---QKELRLLRGKTIE 577
+ K+VL+ V + D E ++ ++ P KH ++ + ++ R L T+E
Sbjct: 783 EMKKIVLKVVKQCCGT--DGVEANYIKT-EILPPFFKHFWQHRMALDRRNYRQLVDTTVE 839
Query: 578 CISLIGLAVGKEKFMQDASD--------VMQLLLKTQTDFNDMEDDDP------------ 617
+ +G A + + D D VM+ + K + + D
Sbjct: 840 LANKVGAAEIISRIVDDLKDEAEQYRKMVMETIEKIMGNLGAADIDHKLEEQLIDGILYA 899
Query: 618 ------QISYMISAWARMCKILGKEFQQYLPVVMGPLM-----KTASIKPEVA 659
+ S M++ + + LGK + YLP + G ++ K+A ++ + A
Sbjct: 900 FQEQTTEDSVMLNGFGTVVNALGKRVKPYLPQICGTVLWRLNNKSAKVRQQAA 952
>gi|118918407 spectrin repeat containing, nuclear envelope 2 isoform 5
[Homo sapiens]
Length = 6907
Score = 36.6 bits (83), Expect = 0.14
Identities = 40/158 (25%), Positives = 75/158 (47%), Gaps = 21/158 (13%)
Query: 454 KKFHEKV--IAALLQTMEDQGNQRVQAHAAAALINFTEDCPKSLLIPYLDNLVKHLHSIM 511
KKF +K + +LL+ ++ QGN ++ + F+E+ P+L+ +KHLH +
Sbjct: 2186 KKFLKKAQDLTSLLKELKSQGNYLLECTKNPS---FSEE-------PWLE--IKHLHESL 2233
Query: 512 VLKLQELIQKGTKLVLEQ-----VVTSIASVADTAEEKFVPYYDLFMPSLKHIVENAVQK 566
+ +LQ+ +Q V E VT + + D ++FV + D P + VE +QK
Sbjct: 2234 LQQLQDSVQNLDGHVREHDSYQVCVTDLNTTLDNFSKEFVSFSD--KPVDQIAVEEKLQK 2291
Query: 567 ELRLLRGKTIECISLIGLAVGKEKFMQDASDVMQLLLK 604
L +++ +L + + Q+ S V Q ++K
Sbjct: 2292 LQELENRLSLQDGTLKKILALAKSVKQNTSSVGQKIIK 2329
>gi|118918403 spectrin repeat containing, nuclear envelope 2 isoform 1
[Homo sapiens]
Length = 6885
Score = 36.6 bits (83), Expect = 0.14
Identities = 40/158 (25%), Positives = 75/158 (47%), Gaps = 21/158 (13%)
Query: 454 KKFHEKV--IAALLQTMEDQGNQRVQAHAAAALINFTEDCPKSLLIPYLDNLVKHLHSIM 511
KKF +K + +LL+ ++ QGN ++ + F+E+ P+L+ +KHLH +
Sbjct: 2186 KKFLKKAQDLTSLLKELKSQGNYLLECTKNPS---FSEE-------PWLE--IKHLHESL 2233
Query: 512 VLKLQELIQKGTKLVLEQ-----VVTSIASVADTAEEKFVPYYDLFMPSLKHIVENAVQK 566
+ +LQ+ +Q V E VT + + D ++FV + D P + VE +QK
Sbjct: 2234 LQQLQDSVQNLDGHVREHDSYQVCVTDLNTTLDNFSKEFVSFSD--KPVDQIAVEEKLQK 2291
Query: 567 ELRLLRGKTIECISLIGLAVGKEKFMQDASDVMQLLLK 604
L +++ +L + + Q+ S V Q ++K
Sbjct: 2292 LQELENRLSLQDGTLKKILALAKSVKQNTSSVGQKIIK 2329
>gi|6912734 transportin 3 [Homo sapiens]
Length = 923
Score = 35.4 bits (80), Expect = 0.30
Identities = 36/150 (24%), Positives = 69/150 (46%), Gaps = 14/150 (9%)
Query: 387 NPDWKYRHAGLMALSAIGEGCHQQMEGILNEIVNFVLLFLQDPHPRVRYAACNAVGQMA- 445
NP W+ A L ++AI + + L E++ V+ + H VRY + VG+M+
Sbjct: 431 NPPWEVTEAVLFIMAAIAKSVDPENNPTLVEVLEGVVRLPETVHTAVRYTSIELVGEMSE 490
Query: 446 -TDFAPGFQKKFHEKVIAALLQTMEDQGNQRVQAHAAAALINFTEDCPKSLLIPYLDNLV 504
D P +F + V+ L++ + + + + + AA A+ N C + + + + L+
Sbjct: 491 VVDRNP----QFLDPVLGYLMKGLCE---KPLASAAAKAIHNICSVC-RDHMAQHFNGLL 542
Query: 505 KHLHSIMVLKLQEL----IQKGTKLVLEQV 530
+ S+ L + KGT LVL ++
Sbjct: 543 EIARSLDSFLLSPEAAVGLLKGTALVLARL 572
>gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens]
Length = 699
Score = 34.7 bits (78), Expect = 0.52
Identities = 24/83 (28%), Positives = 42/83 (50%), Gaps = 3/83 (3%)
Query: 773 KAIGTEPDSDVLSEIMHSFAKCIEVMGDGCLNNEHFEELGGILKAKL--EEHFKNQELRQ 830
+A+ +E D +V E + E G L +E + GG K + E +Q+ RQ
Sbjct: 209 EALQSEEDEEVKEEDTEQKRETPESRNQGQLYSEG-DSRGGDRKQRPGEERRLAHQQQRQ 267
Query: 831 VKRQDEDYDEQVEESLQDEDDND 853
+ ++ED +E+ EE +DE+D +
Sbjct: 268 GREEEEDEEEEGEEGEEDEEDEE 290
>gi|241982712 TBP-interacting protein isoform 1 [Homo sapiens]
Length = 1236
Score = 34.3 bits (77), Expect = 0.68
Identities = 28/128 (21%), Positives = 49/128 (38%)
Query: 146 QWPEGLKFLFDSVSSQNVGLREAALHIFWNFPGIFGNQQQHYLDVIKRMLVQCMQDQEHP 205
Q P +K L + ++V R+ + G+ ++ V+ ++ + D+
Sbjct: 433 QVPLVVKALQRQLKDRSVRARQGCFSLLTELAGVLPGSLAEHMPVLVSGIIFSLADRSSS 492
Query: 206 SIRTLSARATAAFILANEHNVALFKHFADLLPGFLQAVNDSCYQNDDSVLKSLVEIADTV 265
S + A A +L E A H LLP + V DS Y+ L L E+ +
Sbjct: 493 STIRMDALAFLQGLLGTEPAEAFHPHLPILLPPVMACVADSFYKIAAEALVVLQELVRAL 552
Query: 266 PKYLRPHL 273
RP +
Sbjct: 553 WPLHRPRM 560
>gi|112420977 TBP-interacting protein isoform 2 [Homo sapiens]
Length = 1119
Score = 34.3 bits (77), Expect = 0.68
Identities = 28/128 (21%), Positives = 49/128 (38%)
Query: 146 QWPEGLKFLFDSVSSQNVGLREAALHIFWNFPGIFGNQQQHYLDVIKRMLVQCMQDQEHP 205
Q P +K L + ++V R+ + G+ ++ V+ ++ + D+
Sbjct: 340 QVPLVVKALQRQLKDRSVRARQGCFSLLTELAGVLPGSLAEHMPVLVSGIIFSLADRSSS 399
Query: 206 SIRTLSARATAAFILANEHNVALFKHFADLLPGFLQAVNDSCYQNDDSVLKSLVEIADTV 265
S + A A +L E A H LLP + V DS Y+ L L E+ +
Sbjct: 400 STIRMDALAFLQGLLGTEPAEAFHPHLPILLPPVMACVADSFYKIAAEALVVLQELVRAL 459
Query: 266 PKYLRPHL 273
RP +
Sbjct: 460 WPLHRPRM 467
>gi|42558270 HEAT repeat containing 4 [Homo sapiens]
Length = 979
Score = 34.3 bits (77), Expect = 0.68
Identities = 34/133 (25%), Positives = 63/133 (47%), Gaps = 22/133 (16%)
Query: 359 SALDRMACGLGGKLVL--PMIKEHIMQMLQ-NPDWKYRHAGLMALSAIGEGCHQQMEGIL 415
+A+ R AC G L + M+ E ++ ++Q +P WK + + AL IG Q+ L
Sbjct: 696 TAVRRAACLAAGALQIRDKMVLECLLNLMQRDPYWKIKAFAIRALGQIG-----QVSPEL 750
Query: 416 NEIVNFVLLFLQDPHPRVRYAACNAV------GQMATD-FAPGFQKKFHEKVIAALLQTM 468
+++ + + + + P VR AC ++ G D F + H+ V+ + QTM
Sbjct: 751 TDLLLWAIHY--EESPGVRLEACRSILALKLQGDRVRDTFLDVLLLENHDAVLKEMYQTM 808
Query: 469 E-----DQGNQRV 476
+ ++GNQ +
Sbjct: 809 KILNLGNEGNQEM 821
>gi|32189362 PTPRF interacting protein alpha 3 [Homo sapiens]
Length = 1194
Score = 33.9 bits (76), Expect = 0.88
Identities = 26/88 (29%), Positives = 49/88 (55%), Gaps = 5/88 (5%)
Query: 762 QMWHFMCDALIKAIGTEPDSDVLSEIMHSFAKCIEVMGDGCLNNEHFEELGGILKAKLEE 821
Q+ ++ DA K T ++ L EI A+ + + + +FEE L+A+LEE
Sbjct: 349 QLAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEE 408
Query: 822 HFKNQEL---RQVKRQDEDYDEQVEESL 846
KNQEL RQ ++ ++D+++++ E++
Sbjct: 409 --KNQELQRARQREKMNDDHNKRLSETV 434
>gi|6912678 sperm associated antigen 6 isoform 1 [Homo sapiens]
Length = 509
Score = 33.9 bits (76), Expect = 0.88
Identities = 28/99 (28%), Positives = 47/99 (47%), Gaps = 2/99 (2%)
Query: 380 HIMQMLQNPDWKYRHAGLMALSAIGEGCHQQMEGILN-EIVNFVLLFLQDPHPRVRYAAC 438
H+ QM+ NPD K +H L ALS + + E ++ EI VL L+D V+ A
Sbjct: 213 HLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNAS 272
Query: 439 NAVGQMATDFAPGFQKKFHEKVIAALLQTMED-QGNQRV 476
+ ++A Q + +AA++ + +GN R+
Sbjct: 273 TLIREIAKHTPELSQLVVNAGGVAAVIDCIGSCKGNTRL 311
>gi|27262641 sperm associated antigen 6 isoform 2 [Homo sapiens]
Length = 458
Score = 33.9 bits (76), Expect = 0.88
Identities = 28/99 (28%), Positives = 47/99 (47%), Gaps = 2/99 (2%)
Query: 380 HIMQMLQNPDWKYRHAGLMALSAIGEGCHQQMEGILN-EIVNFVLLFLQDPHPRVRYAAC 438
H+ QM+ NPD K +H L ALS + + E ++ EI VL L+D V+ A
Sbjct: 213 HLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMVVEAEIFPVVLTCLKDKDEYVKKNAS 272
Query: 439 NAVGQMATDFAPGFQKKFHEKVIAALLQTMED-QGNQRV 476
+ ++A Q + +AA++ + +GN R+
Sbjct: 273 TLIREIAKHTPELSQLVVNAGGVAAVIDCIGSCKGNTRL 311
>gi|22094987 raptor isoform 1 [Homo sapiens]
Length = 1335
Score = 33.5 bits (75), Expect = 1.2
Identities = 37/174 (21%), Positives = 75/174 (43%), Gaps = 18/174 (10%)
Query: 379 EHIMQMLQNPDWKYRHAGLMA--LSAIGEGCHQQMEGILN-EIVNFVLLFLQDPHPRVRY 435
++ + +L +P H + A L+ I H E L ++ L L DPHP +R
Sbjct: 516 KYFLSVLADPYMPAEHRTMTAFILAVIVNSYHTGQEACLQGNLIAICLEQLNDPHPLLRQ 575
Query: 436 AACNAVGQMATDFAP----GFQKKFHEKVIAALLQTMEDQGNQRVQAHAAAALINFTEDC 491
+G++ +F G + HEK+ + L + + V+ A AL F +
Sbjct: 576 WVAICLGRIWQNFDSARWCGVRDSAHEKLYSLLSDPIPE-----VRCAAVFALGTFVGNS 630
Query: 492 PKSLLIPYLDNLVKHLHSIMVLKLQELIQKGTKLVLEQVVTSIASVADTAEEKF 545
+ D+ H++ ++ L +L+ G+ +V +++V +++ + E F
Sbjct: 631 AER-----TDHSTTIDHNVAMM-LAQLVSDGSPMVRKELVVALSHLVVQYESNF 678
>gi|145587088 hypothetical protein LOC165186 [Homo sapiens]
Length = 1019
Score = 33.5 bits (75), Expect = 1.2
Identities = 25/110 (22%), Positives = 53/110 (48%), Gaps = 4/110 (3%)
Query: 382 MQMLQNPDWKYRHAGLMALSAIGEGCHQQ-MEGILNEIVNFVLLFLQDPHPRVRYAACNA 440
+Q L + DW+ + GL+++ + CH + + G L+++ V + + +V + A +
Sbjct: 496 LQCLNSSDWQMKEKGLVSIQRLA-ACHSEVLTGKLHDVCLVVTGEVTNLRSKVSHLAIST 554
Query: 441 VGQMATDFAPGFQKKFHEKVIAALLQTMEDQGNQRVQAHAAAALINFTED 490
+G + ++ E++ LLQ M D N+ +Q A +L E+
Sbjct: 555 LGDLFQALKKNMDQE-AEEIARCLLQKMADT-NEFIQRAAGQSLRAMVEN 602
>gi|4826730 FK506 binding protein 12-rapamycin associated protein 1
[Homo sapiens]
Length = 2549
Score = 32.7 bits (73), Expect = 2.0
Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 4/91 (4%)
Query: 882 LLPLIVNLI-CPHRPWPDRQWGLCIFDDVIEHCSPASFKYAEYFLRPMLQYVCDNSPEVR 940
LLP IV L P P P R+ L D + E YA + P+++ + D SPE+R
Sbjct: 1114 LLPPIVKLFDAPEAPLPSRKAALETVDRLTESLDFTD--YASRIIHPIVRTL-DQSPELR 1170
Query: 941 QAAAYGLGVMAQYGGDNYRPFCTEALPLLVR 971
A L + G Y+ F +LVR
Sbjct: 1171 STAMDTLSSLVFQLGKKYQIFIPMVNKVLVR 1201
>gi|21361794 TIP120 protein [Homo sapiens]
Length = 1230
Score = 32.3 bits (72), Expect = 2.6
Identities = 58/307 (18%), Positives = 118/307 (38%), Gaps = 31/307 (10%)
Query: 200 QDQEHPSIRTLSARATAAFILANEHNVALFKHFADLLPGFLQAVNDSCYQND---DSVLK 256
+ + S++T L N AL +H L+PG + ++ND ++ D++
Sbjct: 441 KQMKEKSVKTRQCCFNMLTELVNVLPGALTQHIPVLVPGIIFSLNDKSSSSNLKIDALSC 500
Query: 257 SLVEIADTVPKYLRPHLEATLQLSLKLCGD-----TSLNNMQRQLALEVIVTLSETAAAM 311
V + + P+ PH++A + + GD TS + Q ++VI L + ++
Sbjct: 501 LYVILCNHSPQVFHPHVQALVPPVVACVGDPFYKITSEALLVTQQLVKVIRPLDQPSSFD 560
Query: 312 LRKH-TNIVAQTIPQMLAMMVDLEEDEDWANADELEDDDFDSNAVAGESALDRMACGLGG 370
+ ++ TI ++ A +D E E S + ++ C LG
Sbjct: 561 ATPYIKDLFTCTIKRLKAADIDQEVKE------------------RAISCMGQIICNLGD 602
Query: 371 KL--VLPMIKEHIMQMLQNPDWKYRHAGLMALSAIGEGCHQQMEGILNEIVNFVLLFLQD 428
L LP + ++ L+N + + L A G + +L E V + FL+
Sbjct: 603 NLGSDLPNTLQIFLERLKNEITRLTTVKALTLIA-GSPLKIDLRPVLGEGVPILASFLRK 661
Query: 429 PHPRVRYAACNAVGQMATDFAPGFQKKFHEKVIAALLQTMEDQGNQRVQAHAAAALINFT 488
++ +A+ + +++ + V+ L + + + V A + L
Sbjct: 662 NQRALKLGTLSALDILIKNYSDSLTAAMIDAVLDE-LPPLISESDMHVSQMAISFLTTLA 720
Query: 489 EDCPKSL 495
+ P SL
Sbjct: 721 KVYPSSL 727
>gi|21237808 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin c2 isoform b [Homo sapiens]
Length = 1130
Score = 32.3 bits (72), Expect = 2.6
Identities = 31/107 (28%), Positives = 48/107 (44%), Gaps = 15/107 (14%)
Query: 634 GKEFQQYLPVVMGPLMKTASIKPEVALLDTQDMENMSDDDGWEFVNLGDQQSFGIKTAGL 693
GKE +P +TA KPE+ +Q M N D G E D Q+FG++T
Sbjct: 564 GKELDDLVP-------ETAKGKPELQTSASQQMLNFPDK-GKEKPT--DMQNFGLRTDMY 613
Query: 694 EEKSTACQMLVCYAKELKEGFVEYTEQVVKLMVPLLKFYFHDGVRVA 740
+K+ + +K E+TEQ L++ L+ Y D +V+
Sbjct: 614 TKKNVPSK-----SKAAASATREWTEQETLLLLEALEMYKDDWNKVS 655
>gi|194363725 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin c2 isoform c [Homo sapiens]
Length = 1152
Score = 32.3 bits (72), Expect = 2.6
Identities = 31/107 (28%), Positives = 48/107 (44%), Gaps = 15/107 (14%)
Query: 634 GKEFQQYLPVVMGPLMKTASIKPEVALLDTQDMENMSDDDGWEFVNLGDQQSFGIKTAGL 693
GKE +P +TA KPE+ +Q M N D G E D Q+FG++T
Sbjct: 564 GKELDDLVP-------ETAKGKPELQTSASQQMLNFPDK-GKEKPT--DMQNFGLRTDMY 613
Query: 694 EEKSTACQMLVCYAKELKEGFVEYTEQVVKLMVPLLKFYFHDGVRVA 740
+K+ + +K E+TEQ L++ L+ Y D +V+
Sbjct: 614 TKKNVPSK-----SKAAASATREWTEQETLLLLEALEMYKDDWNKVS 655
>gi|194578923 sperm associated antigen 9 isoform 1 [Homo sapiens]
Length = 1321
Score = 32.0 bits (71), Expect = 3.4
Identities = 15/45 (33%), Positives = 26/45 (57%)
Query: 810 ELGGILKAKLEEHFKNQELRQVKRQDEDYDEQVEESLQDEDDNDV 854
EL + +AKL+ KN+EL + R+ E + +D+DD+D+
Sbjct: 451 ELEAVKQAKLKLEEKNRELEEELRKARAEAEDARQKAKDDDDSDI 495
>gi|27436920 sperm associated antigen 9 isoform 3 [Homo sapiens]
Length = 1307
Score = 32.0 bits (71), Expect = 3.4
Identities = 15/45 (33%), Positives = 26/45 (57%)
Query: 810 ELGGILKAKLEEHFKNQELRQVKRQDEDYDEQVEESLQDEDDNDV 854
EL + +AKL+ KN+EL + R+ E + +D+DD+D+
Sbjct: 437 ELEAVKQAKLKLEEKNRELEEELRKARAEAEDARQKAKDDDDSDI 481
>gi|109715866 FERM domain containing 6 [Homo sapiens]
Length = 614
Score = 32.0 bits (71), Expect = 3.4
Identities = 24/88 (27%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
Query: 769 DALIKAIGTEPDSDVLSEIMHSFAKCIEVMGDGCLNNEHFEELGGILKAKLEEHFKNQEL 828
+A K T P+ S +H K M ++ E GG K +LEE ++ E+
Sbjct: 390 EADTKPRDTGPEDSYSSSAIHRKLKTCSSMTSHGSSHTSGVESGG--KDRLEEDLQDDEI 447
Query: 829 RQVKRQDEDYDEQVEESLQDEDDNDVYI 856
+ D ++ EESL+ D +YI
Sbjct: 448 EMLVDDPRDLEQMNEESLEVSPDMCIYI 475
>gi|22748721 FERM domain containing 6 [Homo sapiens]
Length = 614
Score = 32.0 bits (71), Expect = 3.4
Identities = 24/88 (27%), Positives = 38/88 (43%), Gaps = 2/88 (2%)
Query: 769 DALIKAIGTEPDSDVLSEIMHSFAKCIEVMGDGCLNNEHFEELGGILKAKLEEHFKNQEL 828
+A K T P+ S +H K M ++ E GG K +LEE ++ E+
Sbjct: 390 EADTKPRDTGPEDSYSSSAIHRKLKTCSSMTSHGSSHTSGVESGG--KDRLEEDLQDDEI 447
Query: 829 RQVKRQDEDYDEQVEESLQDEDDNDVYI 856
+ D ++ EESL+ D +YI
Sbjct: 448 EMLVDDPRDLEQMNEESLEVSPDMCIYI 475
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,203,971
Number of Sequences: 37866
Number of extensions: 1683375
Number of successful extensions: 5787
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 29
Number of HSP's that attempted gapping in prelim test: 5676
Number of HSP's gapped (non-prelim): 125
length of query: 1115
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1002
effective length of database: 13,968,660
effective search space: 13996597320
effective search space used: 13996597320
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.