Guide to the Human Genome
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Search of human proteins with 24762236

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|24762236 PRP38 pre-mRNA processing factor 38 (yeast) domain
containing A [Homo sapiens]
         (312 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|24762236 PRP38 pre-mRNA processing factor 38 (yeast) domain c...   635   0.0  
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ...    87   2e-17
gi|52426743 cisplatin resistance-associated overexpressed protei...    82   5e-16
gi|19923485 cisplatin resistance-associated overexpressed protei...    82   5e-16
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        70   2e-12
gi|116812577 LUC7-like 2 [Homo sapiens]                                70   3e-12
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]           68   1e-11
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]           68   1e-11
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s...    67   2e-11
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s...    67   2e-11
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]     67   3e-11
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi...    66   3e-11
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]      66   3e-11
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         66   3e-11
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]          65   1e-10
gi|41393554 LUC7-like isoform b [Homo sapiens]                         64   1e-10
gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]           64   2e-10
gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]           64   2e-10
gi|24307919 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) [Ho...    63   4e-10
gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]       63   4e-10
gi|8922297 LUC7-like isoform a [Homo sapiens]                          62   7e-10
gi|153251865 hypothetical protein LOC84226 [Homo sapiens]              62   7e-10
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ...    62   7e-10
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [...    62   7e-10
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi...    62   9e-10
gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens]       61   1e-09
gi|35493811 RNA binding motif protein 39 isoform a [Homo sapiens]      61   1e-09
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            61   1e-09
gi|122937227 U2-associated SR140 protein [Homo sapiens]                61   1e-09
gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]     60   2e-09

>gi|24762236 PRP38 pre-mRNA processing factor 38 (yeast) domain
           containing A [Homo sapiens]
          Length = 312

 Score =  635 bits (1638), Expect = 0.0
 Identities = 312/312 (100%), Positives = 312/312 (100%)

Query: 1   MANRTVKDAHSIHGTNPQYLVEKIIRTRIYESKYWKEECFGLTAELVVDKAMELRFVGGV 60
           MANRTVKDAHSIHGTNPQYLVEKIIRTRIYESKYWKEECFGLTAELVVDKAMELRFVGGV
Sbjct: 1   MANRTVKDAHSIHGTNPQYLVEKIIRTRIYESKYWKEECFGLTAELVVDKAMELRFVGGV 60

Query: 61  YGGNIKPTPFLCLTLKMLQIQPEKDIIVEFIKNEDFKYVRMLGALYMRLTGTAIDCYKYL 120
           YGGNIKPTPFLCLTLKMLQIQPEKDIIVEFIKNEDFKYVRMLGALYMRLTGTAIDCYKYL
Sbjct: 61  YGGNIKPTPFLCLTLKMLQIQPEKDIIVEFIKNEDFKYVRMLGALYMRLTGTAIDCYKYL 120

Query: 121 EPLYNDYRKIKSQNRNGEFELMHVDEFIDELLHSERVCDIILPRLQKRYVLEEAEQLEPR 180
           EPLYNDYRKIKSQNRNGEFELMHVDEFIDELLHSERVCDIILPRLQKRYVLEEAEQLEPR
Sbjct: 121 EPLYNDYRKIKSQNRNGEFELMHVDEFIDELLHSERVCDIILPRLQKRYVLEEAEQLEPR 180

Query: 181 VSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPR 240
           VSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPR
Sbjct: 181 VSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPR 240

Query: 241 RRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERS 300
           RRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERS
Sbjct: 241 RRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERS 300

Query: 301 KKSHKKSRRGNE 312
           KKSHKKSRRGNE
Sbjct: 301 KKSHKKSRRGNE 312


>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
           containing B [Homo sapiens]
          Length = 546

 Score = 86.7 bits (213), Expect = 2e-17
 Identities = 95/334 (28%), Positives = 134/334 (40%), Gaps = 62/334 (18%)

Query: 24  IIRTRIYESKYWKEECFGL-TAELVVDK------------------AMELRFVGGVYG-- 62
           +I T I  S Y+K + + L T   VVD+                  A +    GGV G  
Sbjct: 61  MILTNILSSPYFKVQLYELKTYHEVVDEIYFKVTHVEPWEKGSRKTAGQTGMCGGVRGVG 120

Query: 63  -GNIKPTPFLCLTLKMLQIQPEKDIIVEFIKNEDFKYVRMLGALYMRLTGTAIDCYKYLE 121
            G I  T F CL  K+  ++  +  ++  I + D  Y+R LG +Y+R T    D + + E
Sbjct: 121 TGGIVSTAF-CLLYKLFTLKLTRKQVMGLITHTDSPYIRALGFMYIRYTQPPTDLWDWFE 179

Query: 122 PLYNDYRKIKSQNRNGEFELMHVDEFIDELLHSERVCDIILPRLQKRYVLEEAEQLEPRV 181
              +D   +  +   G   +M + E +   L        + PR+         +Q++ R 
Sbjct: 180 SFLDDEEDLDVKAGGGC--VMTIGEMLRSFLTKLEWFSTLFPRIPVPVQKNIDQQIKTRP 237

Query: 182 SALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRR 241
             +++D       E  EE D  +ER      R RS R    PRRSP    RRSRSRS  R
Sbjct: 238 RKIKKD-----GKEGAEEIDRHVER-----RRSRSPRRSLSPRRSP----RRSRSRSHHR 283

Query: 242 R--------------------SRSPKRRSPSPRRERHRSKSPRRHRSRSRDR-RHRSRSK 280
                                 R  K R    RR R   +   R RSRSR+R R RSRS+
Sbjct: 284 EGHGSSSFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSR 343

Query: 281 SPGHHRSHRHRSHSKSPERSKKSHK--KSRRGNE 312
                R  R R   K  ER ++  +     RGNE
Sbjct: 344 DRKGDRRDRDREREKENERGRRRDRDYDKERGNE 377



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 50/129 (38%), Positives = 67/129 (51%), Gaps = 14/129 (10%)

Query: 198 EEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYR-RSRSRSPRRRSRSP---KRRSPSP 253
           +  D   ER    +  RR  RD DK R +   + R RSR RS  +RSR     K+     
Sbjct: 348 DRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDK 407

Query: 254 RRERHR-----SKSPRRH-RSRSRDRRHRSRSKSPGHHRSHRHRSHSKSP----ERSKKS 303
              RHR     SK  ++H RSRSR+R+HRSRS+S    +  R RS  KS     E  +KS
Sbjct: 408 DDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKS 467

Query: 304 HKKSRRGNE 312
           +K+SR G++
Sbjct: 468 NKRSRSGSQ 476



 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 42/125 (33%), Positives = 64/125 (51%), Gaps = 6/125 (4%)

Query: 192 ESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSP 251
           E S+E+    E  E+    D   R +RD DK       ++ RSRSR  + RSRS  R + 
Sbjct: 387 ERSKEQRSRGEVEEKKHKEDKDDRRHRD-DKRDSKKEKKHSRSRSRERKHRSRSRSRNAG 445

Query: 252 SPRRERHRSKSPRRHRSRSRDRRH-RSRSKSPGHHRS---HRHRSHSKSPERSKKSHKKS 307
              R R + KS  +H++ S+++ + RSRS S G   S    + R HS S E+S+K  +  
Sbjct: 446 KRSRSRSKEKS-SKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSK 504

Query: 308 RRGNE 312
            R ++
Sbjct: 505 ERSHK 509



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 50/166 (30%), Positives = 73/166 (43%), Gaps = 37/166 (22%)

Query: 172 EEAEQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPR-RSPTLR 230
           +E E+   R S  +    +VE  + +E++D++  R    D +R S ++    R RS   +
Sbjct: 380 KERERSRER-SKEQRSRGEVEEKKHKEDKDDRRHR----DDKRDSKKEKKHSRSRSRERK 434

Query: 231 YR-RSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDR---------------- 273
           +R RSRSR+  +RSRS  +   S  +   + KS +R RS S+ R                
Sbjct: 435 HRSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSK 494

Query: 274 ---RHRSRSKSPGHHRSH-----------RHRSHSKSPERSKKSHK 305
              R RSRSK   H R H           R RS S   E  +K HK
Sbjct: 495 EKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQHK 540



 Score = 33.1 bits (74), Expect = 0.33
 Identities = 32/144 (22%), Positives = 55/144 (38%), Gaps = 36/144 (25%)

Query: 185 EEDMDDVESSEEEEEEDEKLERVPSPDH-RRRSYRDLDKPRRSPTLRYRRSRSRSPR--- 240
           +ED DD      +++ D K E+  S    R R +R   + R +      RS+ +S +   
Sbjct: 404 KEDKDD--RRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKN 461

Query: 241 -------RRSRS-----------PKRRSPSPRRERHRSKSPRRHRSRS------------ 270
                  +RSRS            K+R  SP +E+ R +S  + RS              
Sbjct: 462 ESKEKSNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDK 521

Query: 271 RDRRHRSRSKSPGHHRSHRHRSHS 294
            DRR     +     + H+++  +
Sbjct: 522 HDRRRSQSIEQESQEKQHKNKDET 545


>gi|52426743 cisplatin resistance-associated overexpressed protein
           [Homo sapiens]
          Length = 432

 Score = 82.4 bits (202), Expect = 5e-16
 Identities = 57/148 (38%), Positives = 85/148 (57%), Gaps = 18/148 (12%)

Query: 172 EEAEQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSY-------RDLDKPR 224
           +E ++ E R    E + ++ E     EEE+ + ER    + R+RS        R  D+ R
Sbjct: 249 KEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDR-R 307

Query: 225 RSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGH 284
            S +  ++RSRSR  RRRSRS  R     RR R   +S R+HRSRSRDRR RS+S+    
Sbjct: 308 CSRSRDHKRSRSRE-RRRSRSRDR-----RRSRSHDRSERKHRSRSRDRR-RSKSRD--- 357

Query: 285 HRSHRHRSHSKSPERSKKSHKKSRRGNE 312
            +S++HRS S+  E+ +KS +K +RG++
Sbjct: 358 RKSYKHRSKSRDREQDRKSKEKEKRGSD 385



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 41/128 (32%), Positives = 65/128 (50%), Gaps = 4/128 (3%)

Query: 182 SALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRR 241
           + +EE  + +    EE + DE+L++       R   R+ ++  R    + RR      + 
Sbjct: 225 ATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERER--KRRREEEEREKE 282

Query: 242 RSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSK 301
           R+R  +RR  S  R RH S++  R  SRSRD + RSRS+     RS R R  S+S +RS+
Sbjct: 283 RARDRERRKRSRSRSRHSSRTSDRRCSRSRDHK-RSRSRERRRSRS-RDRRRSRSHDRSE 340

Query: 302 KSHKKSRR 309
           + H+   R
Sbjct: 341 RKHRSRSR 348



 Score = 33.9 bits (76), Expect = 0.19
 Identities = 32/149 (21%), Positives = 46/149 (30%), Gaps = 29/149 (19%)

Query: 164 RLQKRYVLEEAEQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKP 223
           R + R     + +   R  +   D     S E          R  S D   R +R   + 
Sbjct: 290 RKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRD 349

Query: 224 RRSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPG 283
           RR                             R + R +   +HRS+SRDR    +SK   
Sbjct: 350 RR-----------------------------RSKSRDRKSYKHRSKSRDREQDRKSKEKE 380

Query: 284 HHRSHRHRSHSKSPERSKKSHKKSRRGNE 312
              S   +S  KS  R K+S   +    E
Sbjct: 381 KRGSDDKKSSVKSGSREKQSEDTNTESKE 409


>gi|19923485 cisplatin resistance-associated overexpressed protein
           [Homo sapiens]
          Length = 432

 Score = 82.4 bits (202), Expect = 5e-16
 Identities = 57/148 (38%), Positives = 85/148 (57%), Gaps = 18/148 (12%)

Query: 172 EEAEQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSY-------RDLDKPR 224
           +E ++ E R    E + ++ E     EEE+ + ER    + R+RS        R  D+ R
Sbjct: 249 KEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDR-R 307

Query: 225 RSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGH 284
            S +  ++RSRSR  RRRSRS  R     RR R   +S R+HRSRSRDRR RS+S+    
Sbjct: 308 CSRSRDHKRSRSRE-RRRSRSRDR-----RRSRSHDRSERKHRSRSRDRR-RSKSRD--- 357

Query: 285 HRSHRHRSHSKSPERSKKSHKKSRRGNE 312
            +S++HRS S+  E+ +KS +K +RG++
Sbjct: 358 RKSYKHRSKSRDREQDRKSKEKEKRGSD 385



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 41/128 (32%), Positives = 65/128 (50%), Gaps = 4/128 (3%)

Query: 182 SALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRR 241
           + +EE  + +    EE + DE+L++       R   R+ ++  R    + RR      + 
Sbjct: 225 ATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERER--KRRREEEEREKE 282

Query: 242 RSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSK 301
           R+R  +RR  S  R RH S++  R  SRSRD + RSRS+     RS R R  S+S +RS+
Sbjct: 283 RARDRERRKRSRSRSRHSSRTSDRRCSRSRDHK-RSRSRERRRSRS-RDRRRSRSHDRSE 340

Query: 302 KSHKKSRR 309
           + H+   R
Sbjct: 341 RKHRSRSR 348



 Score = 33.9 bits (76), Expect = 0.19
 Identities = 32/149 (21%), Positives = 46/149 (30%), Gaps = 29/149 (19%)

Query: 164 RLQKRYVLEEAEQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKP 223
           R + R     + +   R  +   D     S E          R  S D   R +R   + 
Sbjct: 290 RKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRD 349

Query: 224 RRSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPG 283
           RR                             R + R +   +HRS+SRDR    +SK   
Sbjct: 350 RR-----------------------------RSKSRDRKSYKHRSKSRDREQDRKSKEKE 380

Query: 284 HHRSHRHRSHSKSPERSKKSHKKSRRGNE 312
              S   +S  KS  R K+S   +    E
Sbjct: 381 KRGSDDKKSSVKSGSREKQSEDTNTESKE 409


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 70.5 bits (171), Expect = 2e-12
 Identities = 52/120 (43%), Positives = 67/120 (55%), Gaps = 15/120 (12%)

Query: 206 RVPSPDHRRRSYRDLDKPR---RSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKS 262
           R  +P  RR   R   + R   RSP  R  RSRSR+P RR RS + R+P+ RR R RS++
Sbjct: 616 RSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRS-RSRTPA-RRGRSRSRT 673

Query: 263 PRRHRSRSRD----RRHRSRSKSPGHHRS------HRHRSHSKSPERSKKSHKKSRRGNE 312
           P R   RSR     RR RSRS++P   RS       R RSHS++P+R  +S   S R N+
Sbjct: 674 PARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNK 733



 Score = 68.6 bits (166), Expect = 7e-12
 Identities = 56/133 (42%), Positives = 68/133 (51%), Gaps = 28/133 (21%)

Query: 206 RVPSPDHRRRSY----------RDLDKPRRSPTLRYRRSRSRSP----RRRSRSPKR--- 248
           R  SP  R RS           R+  +  RS + R  RS SRSP    R RSR+P R   
Sbjct: 524 RSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGR 583

Query: 249 -RSPSPRRERHRSKSPRRHRSRSRD--RRHRSRSKSPGHHRSH-----RHRSHSKSPER- 299
            RS +P R R RS++P R RSRSR   RR RSRS++P   RS      R RS S+SP R 
Sbjct: 584 SRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARR 643

Query: 300 --SKKSHKKSRRG 310
               +S   +RRG
Sbjct: 644 SGRSRSRTPARRG 656



 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 50/119 (42%), Positives = 62/119 (52%), Gaps = 18/119 (15%)

Query: 206 RVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKR-------RSPSPRRERH 258
           R P+   R RS     +  RS T   RRSRSR+P RR RS  R       R+ SP R R 
Sbjct: 576 RTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRS 635

Query: 259 RSKSPRRHRSRSRD----RRHRSRSKSPGHHRSHRHRSHSKSPER---SKKSHKKSRRG 310
           RS+SP R   RSR     RR RSRS++P    + R RS S++P R     +S   +RRG
Sbjct: 636 RSRSPARRSGRSRSRTPARRGRSRSRTP----ARRGRSRSRTPARRSGRSRSRTPARRG 690



 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 51/108 (47%), Positives = 64/108 (59%), Gaps = 8/108 (7%)

Query: 206 RVPSPDHRRRSYRDLDKPR-RSPTLRYRRSRSRSP-RRRSRSPKRRSPSPRRERHRSKSP 263
           R P+   R RS     + R RS T   RRSRSR+P RRRSRS   R+P+ RR R RS++P
Sbjct: 565 RSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRS---RTPA-RRGRSRSRTP 620

Query: 264 RRHRSRSRDR-RHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSRRG 310
            R RSR+R   R RSRS+SP   RS R RS + +     +S   +RRG
Sbjct: 621 ARRRSRTRSPVRRRSRSRSPA-RRSGRSRSRTPARRGRSRSRTPARRG 667



 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 47/107 (43%), Positives = 60/107 (56%), Gaps = 12/107 (11%)

Query: 206 RVPSPDHRRRSYRDLDKPR--RSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSP 263
           R  +P  R RS       R  RS T   RRSRSR+P RR RS   RS +P R R R++SP
Sbjct: 574 RSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRS---RSRTPARRRSRTRSP 630

Query: 264 RRHRSRSRD---RRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKS 307
            R RSRSR    R  RSRS++P    + R RS S++P R  +S  ++
Sbjct: 631 VRRRSRSRSPARRSGRSRSRTP----ARRGRSRSRTPARRGRSRSRT 673



 Score = 61.6 bits (148), Expect = 9e-10
 Identities = 40/96 (41%), Positives = 53/96 (55%), Gaps = 1/96 (1%)

Query: 213 RRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRD 272
           R R+     + R     R  RSRSR+P RRS   + R+P+ RR R RS++PRR RSRSR 
Sbjct: 648 RSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPA-RRGRSRSRTPRRGRSRSRS 706

Query: 273 RRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSR 308
              R RS S    R  R  S S+   +S+ S ++SR
Sbjct: 707 LVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSR 742



 Score = 61.6 bits (148), Expect = 9e-10
 Identities = 49/112 (43%), Positives = 58/112 (51%), Gaps = 11/112 (9%)

Query: 206 RVPSPDHRRRSYRDLDKPR---RSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKS 262
           R P+   R RS     + R   R+P  R  RSRSR+P RR RS   RS +PRR R RS+S
Sbjct: 650 RTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRS---RSRTPRRGRSRSRS 706

Query: 263 -PRRHRSRSRDRRHRSRSKSPGHH----RSHRHRSHSKSPERSKKSHKKSRR 309
             RR RS SR  + R RS S        R+ + RS S S    KKS   SRR
Sbjct: 707 LVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRR 758



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 45/93 (48%), Positives = 59/93 (63%), Gaps = 12/93 (12%)

Query: 225 RSPTLRYRRSRSRSPR-RRSRSPKR--RSPSPRRERHRSKSPRRHR-SRSRDRRHRSRSK 280
           R+PT R   SRSRSP+ RRSRS +R  RS SP+R R RS+SP+R   SRSR+ + R RS+
Sbjct: 498 RTPTKR-GHSRSRSPQWRRSRSAQRWGRSRSPQR-RGRSRSPQRPGWSRSRNTQRRGRSR 555

Query: 281 SPGHHRSH------RHRSHSKSPERSKKSHKKS 307
           S    RSH      R RS S++P R  +S  ++
Sbjct: 556 SARRGRSHSRSPATRGRSRSRTPARRGRSRSRT 588



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 45/133 (33%), Positives = 58/133 (43%), Gaps = 19/133 (14%)

Query: 194  SEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSP 253
            S       E   R P P HRR       +P        RR  + SPR ++ S + RSPSP
Sbjct: 1707 SRSASSSPETRSRTP-PRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSP 1765

Query: 254  R---RERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRS--------------HSKS 296
            +    +R RS+S RR ++R+  RR RS S      R  R RS              HS+S
Sbjct: 1766 KPRGLQRSRSRS-RREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRS 1824

Query: 297  PERSKKSHKKSRR 309
            P R + S   SRR
Sbjct: 1825 PARQESSRTSSRR 1837



 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 55/203 (27%), Positives = 88/203 (43%), Gaps = 22/203 (10%)

Query: 128 RKIKSQNRNGEFELMHVDEFIDELLHSERVCDIILPRLQKRYVLEEAEQLEPRVSALEED 187
           RK + + R  E E M  ++  +E    E+V    L  L+K       E+   +  A+ E 
Sbjct: 62  RKRRVELRCLELEEMMEEQGYEEQQIQEKVATFRLMLLEKDVNPGGKEETPGQRPAVTET 121

Query: 188 MDDVESSEEEEEE-------DEKLERVPSPDHRRRSYRDLDKPRRSPTLRY----RRSRS 236
               E +E++ E         +      S D +RR+ R+  +P   P   Y      S S
Sbjct: 122 HQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRA-REAKQPAPEPPKPYSLVRESSSS 180

Query: 237 RSP--------RRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSH 288
           RSP        +++ R  +  S SPRRER +S   ++HRS S  ++ + RS +P   R  
Sbjct: 181 RSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKS 240

Query: 289 RHRSHSKSPERSKKSHKKSRRGN 311
           + +   +S  RS     KSRR +
Sbjct: 241 KDKKRKRS--RSTTPAPKSRRAH 261



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 43/102 (42%), Positives = 52/102 (50%), Gaps = 8/102 (7%)

Query: 208  PSPDHRRRSYRDLDKPRRS----PTLRYRRSRSR-SPRRRSRSPKRRSPSPRRERHRSKS 262
            P+P  R RS       RRS    P +  RRSRSR SP  R RS  R S + RR R R+  
Sbjct: 1858 PAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASP 1917

Query: 263  PRRHRSRSRD---RRHRSRSKSPGHHRSHRHRSHSKSPERSK 301
              R RSRSR     R RSRS++P   R  R R+   +  RS+
Sbjct: 1918 VSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSR 1959



 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 45/107 (42%), Positives = 55/107 (51%), Gaps = 17/107 (15%)

Query: 209  SPDHRRRSYRDLDKPRRSPTLRYRRSRSRS---PRRRSRSPKRRSPSPRRERHRSKSPRR 265
            SP  RRRS     + R SP  R RRSRSR+    RRRSRS   R+P   R R RS++P  
Sbjct: 1987 SPVTRRRS-----RSRTSPVTR-RRSRSRTSPVTRRRSRS---RTPPAIRRRSRSRTPLL 2037

Query: 266  HRSRSRDR-----RHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKS 307
             R RSR R     R RSRS++P   R  R  + S    R + +   S
Sbjct: 2038 PRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSS 2084



 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 37/111 (33%), Positives = 54/111 (48%), Gaps = 9/111 (8%)

Query: 209  SPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSPR----RERHRSKSPR 264
            +P  RR S    +  R++   R  RS S SP  RSR+P R   SP         +S+S R
Sbjct: 1684 TPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSR 1743

Query: 265  RHRS----RSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSRRGN 311
            R RS    R++    R RS SP      R RS S+  E+++ + ++ R G+
Sbjct: 1744 RRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRR-EKTRTTRRRDRSGS 1793



 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 49/108 (45%), Positives = 59/108 (54%), Gaps = 20/108 (18%)

Query: 209  SPDHRRRSY------RDLDKPRRSPTLRYRRSRSRSP---RRRSRSPKRRSPSPRRERHR 259
            SP  RRRS       R   + R SP  R RRSRSR+P   RRRSRS   R+P+ RR R R
Sbjct: 1893 SPVSRRRSRSRTSVTRRRSRSRASPVSR-RRSRSRTPPVTRRRSRS---RTPTTRR-RSR 1947

Query: 260  SKSPRRHRSRSRDR-----RHRSRSK-SPGHHRSHRHRSHSKSPERSK 301
            S++P   R RSR R     R RSRS+ SP   R  R R+   +  RS+
Sbjct: 1948 SRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSR 1995



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 36/105 (34%), Positives = 54/105 (51%), Gaps = 7/105 (6%)

Query: 206 RVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRER-HRSKSPR 264
           R P+P  +++  +  D+ RRS +   RR R +S +++    K RS S  ++R HRS +P+
Sbjct: 181 RSPTPKQKKKKKKK-DRGRRSESSSPRRERKKSSKKK----KHRSESESKKRKHRSPTPK 235

Query: 265 RHRSRSRDRRHRSRSKSPGHHRSHRHRSHS-KSPERSKKSHKKSR 308
             R     +R RSRS +P       HRS S  S   S  S  +SR
Sbjct: 236 SKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSR 280



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 42/93 (45%), Positives = 52/93 (55%), Gaps = 12/93 (12%)

Query: 213  RRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSP-SPRRERHRSKSPRRHRSRSR 271
            RRRS     + R SP  R RRSRSR+   R RS  R SP S RR R R+    R RSRSR
Sbjct: 1885 RRRS-----RSRTSPVSR-RRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSR 1938

Query: 272  --DRRHRSRSKSPGHHRSHRHRSHSKSPERSKK 302
                R RSRS++P      R RS S++P  +++
Sbjct: 1939 TPTTRRRSRSRTP---PVTRRRSRSRTPPVTRR 1968



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 47/113 (41%), Positives = 57/113 (50%), Gaps = 24/113 (21%)

Query: 206  RVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSP---RRRSRSPKRRSP-SPRRERHRSK 261
            R  +P  RRRS        R+P +  RRSRSR+P   RRRSRS  R SP + RR R R+ 
Sbjct: 1936 RSRTPTTRRRSRS------RTPPVTRRRSRSRTPPVTRRRSRS--RTSPITRRRSRSRTS 1987

Query: 262  SPRRHRSRSRD-----RRHRSRSKSPGHHRSH-------RHRSHSKSPERSKK 302
               R RSRSR      RR RSR+      RS        R RS S++P   +K
Sbjct: 1988 PVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRK 2040



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 48/112 (42%), Positives = 61/112 (54%), Gaps = 20/112 (17%)

Query: 209  SPDHRRRSYRDLDKPRRSPTLRYRRSRSRSP---RRRSRSPKRRSPSPRRERHRSKSPR- 264
            SP  RRRS     + R SP  R RRSRSR+P   RRRSRS   R+P   R+R RS+SP  
Sbjct: 1999 SPVTRRRS-----RSRTSPVTR-RRSRSRTPPAIRRRSRS---RTPLLPRKRSRSRSPLA 2049

Query: 265  -RHRSRSRD----RRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSRRGN 311
             R RSRSR     R  RS ++SP   R  R  +   S +RS+ +   + R +
Sbjct: 2050 IRRRSRSRTPRTARGKRSLTRSPPAIR--RRSASGSSSDRSRSATPPATRNH 2099



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 48/131 (36%), Positives = 57/131 (43%), Gaps = 23/131 (17%)

Query: 192  ESSEEEEEEDEKLERVPSPDHRRRSYRDLDKP------RRSPTLRYRRSRSRSP---RRR 242
            ESS           R P    +R   R    P      R SP   +RRSRSR+P   RRR
Sbjct: 1829 ESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPAT-HRRSRSRTPLISRRR 1887

Query: 243  SRSPKRRSPSPRRERHRSKSPRRHRSRSRD-----RRHRSRSKSPGHHRSH------RHR 291
            SRS  R SP  RR      S  R RSRSR      RR RSR+      RS       R R
Sbjct: 1888 SRS--RTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRR 1945

Query: 292  SHSKSPERSKK 302
            S S++P  +++
Sbjct: 1946 SRSRTPPVTRR 1956



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 36/105 (34%), Positives = 49/105 (46%), Gaps = 5/105 (4%)

Query: 206  RVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRR 265
            R PSP+    +    + P +S T R     S  P+ +SR+P RR  S        K+   
Sbjct: 1645 RGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLS 1704

Query: 266  HRSRSRDRRHRSRSKSPGHHRSHRHRSHS-KSPERSKKSHKKSRR 309
             RSRS      +RS++P  HR    RS S  SPE ++KS    RR
Sbjct: 1705 RRSRSASSSPETRSRTPPRHR----RSPSVSSPEPAEKSRSSRRR 1745



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 50/152 (32%), Positives = 65/152 (42%), Gaps = 35/152 (23%)

Query: 194 SEEEEEEDEKLERVPSP-DHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRR---SRSP--- 246
           S       E  +  P+P  HR  S     K R     +  +S S +P RR   SRSP   
Sbjct: 431 SRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATA 490

Query: 247 ---KRRSPSPRRERH-RSKSPRRHRSRSRDRRHRSRS----------KSPGHHRS----- 287
              + RS +P +  H RS+SP+  RSRS  R  RSRS          + PG  RS     
Sbjct: 491 KRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQR 550

Query: 288 -------HRHRSHSKSPERSKKSHKK--SRRG 310
                   R RSHS+SP    +S  +  +RRG
Sbjct: 551 RGRSRSARRGRSHSRSPATRGRSRSRTPARRG 582



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 41/130 (31%), Positives = 50/130 (38%), Gaps = 6/130 (4%)

Query: 186  EDMDDVESSEEEEEEDEKLER----VPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRR 241
            E     ESS E   +     R     P P  + R+       R SP L  +   SR  R 
Sbjct: 1650 EGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRS 1709

Query: 242  RSRSPKRRSPSPRRERHRS--KSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPER 299
             S SP+ RS +P R R      SP         RR RS S       S R RS S  P  
Sbjct: 1710 ASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRG 1769

Query: 300  SKKSHKKSRR 309
             ++S  +SRR
Sbjct: 1770 LQRSRSRSRR 1779



 Score = 49.3 bits (116), Expect = 4e-06
 Identities = 48/109 (44%), Positives = 57/109 (52%), Gaps = 21/109 (19%)

Query: 209  SPDHRRRSYRDLDKP-------RRSPTLRYRRSRSRSP---RRRSRSPKRRSPSPRRERH 258
            SP  RRRS R    P        R+PT R RRSRSR+P   RRRSRS   R+P   R R 
Sbjct: 1916 SPVSRRRS-RSRTPPVTRRRSRSRTPTTR-RRSRSRTPPVTRRRSRS---RTPPVTRRRS 1970

Query: 259  RSKSPRRHRSRSRDR-----RHRSRSK-SPGHHRSHRHRSHSKSPERSK 301
            RS++    R RSR R     R RSRS+ SP   R  R R+   +  RS+
Sbjct: 1971 RSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSR 2019



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 38/120 (31%), Positives = 54/120 (45%), Gaps = 25/120 (20%)

Query: 214  RRSYRDLDKPR--RSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKS--------- 262
            RR      KPR  +    R RR ++R+ RRR RS   +S S RR+R RS+S         
Sbjct: 1758 RRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGG 1817

Query: 263  --------PRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKS------HKKSR 308
                     R+  SR+  RR R RS++P   R       S +P +  +S      H++SR
Sbjct: 1818 SGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSR 1877



 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 46/114 (40%), Positives = 57/114 (50%), Gaps = 23/114 (20%)

Query: 218  RDLDKPRRSPTLRYRRSRSRS--PRRR-------SRSPKRRSPS---PRRERHRSKSPRR 265
            RD     +S + R +RSRSRS   RRR       SRSP R+  S    RR R RS++P  
Sbjct: 1788 RDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPT 1847

Query: 266  HRSRSRDRRH-----RSRSK-SPGHHRSHRHRSHSKSPERSKK-----SHKKSR 308
             R RSR R       RSRS+ SP  HR  R R+   S  RS+      S ++SR
Sbjct: 1848 SRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSR 1901



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 40/87 (45%), Positives = 46/87 (52%), Gaps = 5/87 (5%)

Query: 225 RSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGH 284
           RS T R  RSRSRS  RR RS  R     RR R  S S R+++SR+  RR RS S SP  
Sbjct: 693 RSRTPRRGRSRSRSLVRRGRSHSR--TPQRRGRSGSSSERKNKSRTSQRRSRSNS-SPEM 749

Query: 285 HRSH--RHRSHSKSPERSKKSHKKSRR 309
            +S     RS S S  RSK   + S R
Sbjct: 750 KKSRISSRRSRSLSSPRSKAKSRLSLR 776



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 35/87 (40%), Positives = 43/87 (49%), Gaps = 7/87 (8%)

Query: 230  RYRRSRSRS-PRRRSRSPKRRSPSP-RRERHRSKSPRRHRSRSRD-----RRHRSRSKSP 282
            R RR RSR+ P  R RS  R SP+P +R R R+      RSRSR      RR RSR+   
Sbjct: 1836 RRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPV 1895

Query: 283  GHHRSHRHRSHSKSPERSKKSHKKSRR 309
               RS    S ++   RS+ S    RR
Sbjct: 1896 SRRRSRSRTSVTRRRSRSRASPVSRRR 1922



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 43/132 (32%), Positives = 58/132 (43%), Gaps = 16/132 (12%)

Query: 192 ESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRR----SPTLRYRRSRSRSPRRRSRSP- 246
           ESS       ++ ++    D  RRS  +   PRR    S   +  RS S S +R+ RSP 
Sbjct: 176 ESSSSRSPTPKQKKKKKKKDRGRRS--ESSSPRRERKKSSKKKKHRSESESKKRKHRSPT 233

Query: 247 ---KRRSPSPRRERHRS-----KSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPE 298
              KR+S   +R+R RS     KS R HRS S D    S   S    RS   ++H+ +  
Sbjct: 234 PKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSA-SSSDTSRSRSRSAAAKTHTTALA 292

Query: 299 RSKKSHKKSRRG 310
               S    RRG
Sbjct: 293 GRSPSPASGRRG 304



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 41/139 (29%), Positives = 56/139 (40%), Gaps = 6/139 (4%)

Query: 176 QLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSR 235
           Q   R  +  E  +   +S+     +   E   S    RRS R L  PR     + R S 
Sbjct: 719 QRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRS-RSLSSPRSKA--KSRLSL 775

Query: 236 SRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRS---HRHRS 292
            RS    S  PK++S +P R      S  + +SR+  RR RS S  P   +S    R   
Sbjct: 776 RRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSH 835

Query: 293 HSKSPERSKKSHKKSRRGN 311
            S SP    KS    R+G+
Sbjct: 836 SSSSPHPKVKSGTPPRQGS 854



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 36/109 (33%), Positives = 51/109 (46%), Gaps = 16/109 (14%)

Query: 209 SPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSP-RRHR 267
           SP+   +S      P      +  R  S SP     SPK  +P+P   R  S SP  ++R
Sbjct: 408 SPEKLPQSSSSESSPPSPQPTKVSRHASSSP----ESPK-PAPAPGSHREISSSPTSKNR 462

Query: 268 SRSRDRRHRSRSKSP----GHHRS----HRHRSHSKSPERSKKSHKKSR 308
           S  R +R +S S +P    G  RS     R RS S++P  +K+ H +SR
Sbjct: 463 SHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTP--TKRGHSRSR 509



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 33/121 (27%), Positives = 43/121 (35%), Gaps = 7/121 (5%)

Query: 193  SSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRR-----RSRSPK 247
            SS              SP   +   + L KP           RSRSPR+     R     
Sbjct: 2632 SSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSL 2691

Query: 248  RRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKS 307
              SP  RR      SPR  +S S +R  R   +      SH+ R  + SP   +  H+ S
Sbjct: 2692 SYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMR--HRSS 2749

Query: 308  R 308
            R
Sbjct: 2750 R 2750



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 43/155 (27%), Positives = 61/155 (39%), Gaps = 34/155 (21%)

Query: 182  SALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRR 241
            S+ E D+    S +E  E D       SPD + ++   L +  RS +     S+SR   R
Sbjct: 1541 SSQELDVKPSASPQERSESDS------SPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPR 1594

Query: 242  RSRS-----------------------PKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSR 278
            RSRS                       P+ ++P+PR    RS+S    + R       S 
Sbjct: 1595 RSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSS 1654

Query: 279  SKSPGHH----RSHRHRSHSKSPERSKKSHKKSRR 309
            ++S   H    R+ R  S S SPE   KS    RR
Sbjct: 1655 TESSPEHPPKSRTARRGSRS-SPEPKTKSRTPPRR 1688



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 45/150 (30%), Positives = 54/150 (36%), Gaps = 37/150 (24%)

Query: 194  SEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPR--------RRSRS 245
            S    E D K    P       S    DKPR +P  +     S  P+        RRSRS
Sbjct: 1579 SGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRS 1638

Query: 246  ---PKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRS--------KSPGHHRS------- 287
                K R PSP        SP  H  +SR  R  SRS        ++P   RS       
Sbjct: 1639 GSSSKGRGPSPEGSSSTESSPE-HPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPEL 1697

Query: 288  -------HRHRSHSKSPE---RSKKSHKKS 307
                    R RS S SPE   R+   H++S
Sbjct: 1698 TRKARLSRRSRSASSSPETRSRTPPRHRRS 1727



 Score = 37.4 bits (85), Expect = 0.017
 Identities = 40/129 (31%), Positives = 54/129 (41%), Gaps = 23/129 (17%)

Query: 205 ERVPSPDHRR--RSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPS---------- 252
           E+  +P  R    S  D +   R+P+ R+  S S  PR +S +P R+SPS          
Sbjct: 862 EQSVTPQRRSCFESSPDPELKSRTPS-RHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVK 920

Query: 253 ----PRRERHR-SKSPRRHRSRSRDRRHRSRSKSPGHHRSHR-----HRSHSKSPERSKK 302
               PR+  H  S SP   R  SR    RSRS SP  +   R       S S SP+   K
Sbjct: 921 AIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVK 980

Query: 303 SHKKSRRGN 311
                R+ +
Sbjct: 981 PETPPRQSH 989



 Score = 37.4 bits (85), Expect = 0.017
 Identities = 37/120 (30%), Positives = 48/120 (40%), Gaps = 4/120 (3%)

Query: 190  DVESSEEEEEEDEKLERVPSPDHR-RRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKR 248
            D E S    + +  L+RVPSP    + + R+   P  +P  R RRS S S    S S   
Sbjct: 2562 DSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSS 2621

Query: 249  RSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSP--ERSKKSHKK 306
             S S       S S     S S      S +K PG     +  S  K P  ER  +S +K
Sbjct: 2622 SSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAK-PGPQALPKPASPKKPPPGERRSRSPRK 2680



 Score = 33.9 bits (76), Expect = 0.19
 Identities = 33/99 (33%), Positives = 47/99 (47%), Gaps = 12/99 (12%)

Query: 223 PRR-SPTLRYRRSRSRSPRRRS-----RSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHR 276
           PR+ S T      +S +P+RRS       P+ +S +P R      SP R +S +  R+  
Sbjct: 850 PRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSP 909

Query: 277 SRSKSPGHH----RSHRHRSH--SKSPERSKKSHKKSRR 309
           SRS SP        S R RSH  S SP  S+ + + + R
Sbjct: 910 SRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPR 948



 Score = 33.1 bits (74), Expect = 0.33
 Identities = 33/93 (35%), Positives = 43/93 (46%), Gaps = 10/93 (10%)

Query: 192  ESSEEEEEEDEK-LERVPSPDHRRR-SYRDLD-KPRRSPTLRYRRSRSRSPRRRSRSPKR 248
            E S  E   D+K + R P     R  S ++LD KP  SP       + RS    S   K 
Sbjct: 1515 ERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASP-------QERSESDSSPDSKA 1567

Query: 249  RSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKS 281
            ++ +P R+R RS S     S+SR    RSRS S
Sbjct: 1568 KTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGS 1600



 Score = 30.4 bits (67), Expect = 2.1
 Identities = 36/128 (28%), Positives = 50/128 (39%), Gaps = 21/128 (16%)

Query: 193 SSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPS 252
           +S +     E   + PS  +  +   D DK  +S T       S SP R S  P+  +P+
Sbjct: 316 TSTQRPSSPETATKQPSSPYEDK---DKDKKEKSAT-----RPSPSPERSSTGPEPPAPT 367

Query: 253 P-RRERH-----------RSKSPRRHRSRSRDRRHRSRSKSPGH-HRSHRHRSHSKSPER 299
           P   ERH            S+ P    S +   R RS  KSP    +S    S   SP+ 
Sbjct: 368 PLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQP 427

Query: 300 SKKSHKKS 307
           +K S   S
Sbjct: 428 TKVSRHAS 435


>gi|116812577 LUC7-like 2 [Homo sapiens]
          Length = 392

 Score = 69.7 bits (169), Expect = 3e-12
 Identities = 51/127 (40%), Positives = 70/127 (55%), Gaps = 10/127 (7%)

Query: 184 LEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRR-R 242
           + E +++++    E++E    ER+   + R R  R+  +  RS +   +RSRSR  RR R
Sbjct: 221 IREKLEELKRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREHRRHR 280

Query: 243 SRSPKRRSPSPRRERHRSKS-PRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSK 301
           SRS  R     R+ R RSKS  +RHR RSR     SRS+S  H RS RH S  +S ERSK
Sbjct: 281 SRSMSRE----RKRRTRSKSREKRHRHRSRSS---SRSRSRSHQRS-RHSSRDRSRERSK 332

Query: 302 KSHKKSR 308
           +   K R
Sbjct: 333 RRSSKER 339



 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 41/110 (37%), Positives = 58/110 (52%), Gaps = 9/110 (8%)

Query: 202 EKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSK 261
           EKLE +      +R   +  + R    L+ R  R R  R + R  +  S +P+R R R  
Sbjct: 223 EKLEEL------KRVVAEKQEKRNQERLKRREEREREEREKLRRSRSHSKNPKRSRSREH 276

Query: 262 SPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSRRGN 311
              R RS SR+R+ R+RSKS    + HRHRS S S  RS +SH++SR  +
Sbjct: 277 RRHRSRSMSRERKRRTRSKS--REKRHRHRSRSSSRSRS-RSHQRSRHSS 323


>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
          Length = 2426

 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 51/149 (34%), Positives = 75/149 (50%), Gaps = 20/149 (13%)

Query: 179  PRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDK----PRRSPTLRYRRS 234
            P VS++ E     ESS EE+++ E   +V     + +  ++ DK     +R  +LR R  
Sbjct: 1770 PVVSSMPERAS--ESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSK 1827

Query: 235  RSRSPRRRSRSPKRRSPSPRRER------HRSKSPRRHRSRSRDRRHRSRSKSPGHH--- 285
            RS+S   +SR     S S  R+R      HRS++  R RSR R R  RSRSKS G     
Sbjct: 1828 RSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVS 1887

Query: 286  -----RSHRHRSHSKSPERSKKSHKKSRR 309
                 RS +HRS S+  +R + S + +R+
Sbjct: 1888 KEKRKRSPKHRSKSRERKRKRSSSRDNRK 1916



 Score = 65.9 bits (159), Expect = 5e-11
 Identities = 54/150 (36%), Positives = 78/150 (52%), Gaps = 13/150 (8%)

Query: 167  KRYVLEEAEQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRS 226
            +R V +E  +  P+  +   +     SS  +  +  +  R  +P  R RS+    + RRS
Sbjct: 1883 RRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRA-RSRTPSRRSRSHTP-SRRRRS 1940

Query: 227  PTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRS---RSKSPG 283
             ++  RRS S SP RRSR+P RRS +P R   RS++P R RSR+  RR R+   RS++P 
Sbjct: 1941 RSVGRRRSFSISPSRRSRTPSRRSRTPSR---RSRTPSR-RSRTPSRRSRTPSRRSRTPS 1996

Query: 284  HHRSH----RHRSHSKSPERSKKSHKKSRR 309
              R      R RS S SP R ++S    RR
Sbjct: 1997 RRRRSRSVVRRRSFSISPVRLRRSRTPLRR 2026



 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 47/142 (33%), Positives = 69/142 (48%), Gaps = 9/142 (6%)

Query: 172  EEAEQLEPRVSALEEDMDDVESSEEEEEE--DEKLERVPSPDHRRRSYRDLDKPRRSPTL 229
            ++ E+ + R S+L       +SSE +  +   E   R      + +S+R   + R     
Sbjct: 1810 DKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRR 1869

Query: 230  RYR--RSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRS 287
            R R  RSRS+S  RRS S ++R  SP+   HRSKS  R R RS  R +R   ++     S
Sbjct: 1870 RRRSSRSRSKSRGRRSVSKEKRKRSPK---HRSKSRERKRKRSSSRDNRKTVRARSRTPS 1926

Query: 288  HRHRSHSKSPERSKKSHKKSRR 309
             R RSH  +P R ++S    RR
Sbjct: 1927 RRSRSH--TPSRRRRSRSVGRR 1946



 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 42/101 (41%), Positives = 50/101 (49%), Gaps = 10/101 (9%)

Query: 208  PSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHR 267
            PS   R  S R     RRS T      RSR+P RRSR+P RRS +P R R RS+S  R R
Sbjct: 1953 PSRRSRTPSRRSRTPSRRSRT---PSRRSRTPSRRSRTPSRRSRTPSRRR-RSRSVVRRR 2008

Query: 268  SRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSR 308
            S S       RS++P        R  S+SP R K+S    R
Sbjct: 2009 SFSISPVRLRRSRTP------LRRRFSRSPIRRKRSRSSER 2043



 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 40/94 (42%), Positives = 47/94 (50%), Gaps = 2/94 (2%)

Query: 206  RVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRR 265
            R PS   R  S R     RRS T   RRSR+ S R R+ S +RRS S  R R  S SP R
Sbjct: 1958 RTPSRRSRTPSRRSRTPSRRSRTPS-RRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVR 2016

Query: 266  HRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPER 299
             R RSR    R  S+SP   +  R     +SP+R
Sbjct: 2017 LR-RSRTPLRRRFSRSPIRRKRSRSSERGRSPKR 2049



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 42/98 (42%), Positives = 47/98 (47%), Gaps = 6/98 (6%)

Query: 193  SSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRR--- 249
            S         +  R PS   R  S R     RRS T   RRSR+ S RRRSRS  RR   
Sbjct: 1952 SPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPS-RRSRTPSRRRRSRSVVRRRSF 2010

Query: 250  SPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRS 287
            S SP R R RS++P R R  SR    R RS+S    RS
Sbjct: 2011 SISPVRLR-RSRTPLRRRF-SRSPIRRKRSRSSERGRS 2046


>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
          Length = 2303

 Score = 67.8 bits (164), Expect = 1e-11
 Identities = 51/149 (34%), Positives = 75/149 (50%), Gaps = 20/149 (13%)

Query: 179  PRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDK----PRRSPTLRYRRS 234
            P VS++ E     ESS EE+++ E   +V     + +  ++ DK     +R  +LR R  
Sbjct: 1770 PVVSSMPERAS--ESSSEEKDDYEIFVKVKDTHEKSKKNKNRDKGEKEKKRDSSLRSRSK 1827

Query: 235  RSRSPRRRSRSPKRRSPSPRRER------HRSKSPRRHRSRSRDRRHRSRSKSPGHH--- 285
            RS+S   +SR     S S  R+R      HRS++  R RSR R R  RSRSKS G     
Sbjct: 1828 RSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVS 1887

Query: 286  -----RSHRHRSHSKSPERSKKSHKKSRR 309
                 RS +HRS S+  +R + S + +R+
Sbjct: 1888 KEKRKRSPKHRSKSRERKRKRSSSRDNRK 1916



 Score = 65.9 bits (159), Expect = 5e-11
 Identities = 54/150 (36%), Positives = 78/150 (52%), Gaps = 13/150 (8%)

Query: 167  KRYVLEEAEQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRS 226
            +R V +E  +  P+  +   +     SS  +  +  +  R  +P  R RS+    + RRS
Sbjct: 1883 RRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRA-RSRTPSRRSRSHTP-SRRRRS 1940

Query: 227  PTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRS---RSKSPG 283
             ++  RRS S SP RRSR+P RRS +P R   RS++P R RSR+  RR R+   RS++P 
Sbjct: 1941 RSVGRRRSFSISPSRRSRTPSRRSRTPSR---RSRTPSR-RSRTPSRRSRTPSRRSRTPS 1996

Query: 284  HHRSH----RHRSHSKSPERSKKSHKKSRR 309
              R      R RS S SP R ++S    RR
Sbjct: 1997 RRRRSRSVVRRRSFSISPVRLRRSRTPLRR 2026



 Score = 60.1 bits (144), Expect = 2e-09
 Identities = 47/142 (33%), Positives = 69/142 (48%), Gaps = 9/142 (6%)

Query: 172  EEAEQLEPRVSALEEDMDDVESSEEEEEE--DEKLERVPSPDHRRRSYRDLDKPRRSPTL 229
            ++ E+ + R S+L       +SSE +  +   E   R      + +S+R   + R     
Sbjct: 1810 DKGEKEKKRDSSLRSRSKRSKSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRR 1869

Query: 230  RYR--RSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRS 287
            R R  RSRS+S  RRS S ++R  SP+   HRSKS  R R RS  R +R   ++     S
Sbjct: 1870 RRRSSRSRSKSRGRRSVSKEKRKRSPK---HRSKSRERKRKRSSSRDNRKTVRARSRTPS 1926

Query: 288  HRHRSHSKSPERSKKSHKKSRR 309
             R RSH  +P R ++S    RR
Sbjct: 1927 RRSRSH--TPSRRRRSRSVGRR 1946



 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 42/101 (41%), Positives = 50/101 (49%), Gaps = 10/101 (9%)

Query: 208  PSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHR 267
            PS   R  S R     RRS T      RSR+P RRSR+P RRS +P R R RS+S  R R
Sbjct: 1953 PSRRSRTPSRRSRTPSRRSRT---PSRRSRTPSRRSRTPSRRSRTPSRRR-RSRSVVRRR 2008

Query: 268  SRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSR 308
            S S       RS++P        R  S+SP R K+S    R
Sbjct: 2009 SFSISPVRLRRSRTP------LRRRFSRSPIRRKRSRSSER 2043



 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 40/94 (42%), Positives = 47/94 (50%), Gaps = 2/94 (2%)

Query: 206  RVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRR 265
            R PS   R  S R     RRS T   RRSR+ S R R+ S +RRS S  R R  S SP R
Sbjct: 1958 RTPSRRSRTPSRRSRTPSRRSRTPS-RRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVR 2016

Query: 266  HRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPER 299
             R RSR    R  S+SP   +  R     +SP+R
Sbjct: 2017 LR-RSRTPLRRRFSRSPIRRKRSRSSERGRSPKR 2049



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 42/98 (42%), Positives = 47/98 (47%), Gaps = 6/98 (6%)

Query: 193  SSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRR--- 249
            S         +  R PS   R  S R     RRS T   RRSR+ S RRRSRS  RR   
Sbjct: 1952 SPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPS-RRSRTPSRRRRSRSVVRRRSF 2010

Query: 250  SPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRS 287
            S SP R R RS++P R R  SR    R RS+S    RS
Sbjct: 2011 SISPVRLR-RSRTPLRRRF-SRSPIRRKRSRSSERGRS 2046


>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
           sapiens]
          Length = 434

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 45/121 (37%), Positives = 66/121 (54%), Gaps = 5/121 (4%)

Query: 192 ESSEEEEEEDEKLERVPSPDHRR-RSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKR-- 248
           E +++E   D+  ER+ S ++   R  R   K  R  +    RSR R  R RSR  K+  
Sbjct: 87  EHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSR 146

Query: 249 -RSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKS 307
            RS   ++ R RS+  ++ RSRSR+R+ R RS+S    R HRHR+ S+S  RS+   +K 
Sbjct: 147 SRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSR-HRHRTRSRSRTRSRSRDRKK 205

Query: 308 R 308
           R
Sbjct: 206 R 206



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 38/123 (30%), Positives = 54/123 (43%), Gaps = 11/123 (8%)

Query: 194 SEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSP 253
           S+++  +  K E     +H     R+      +   R++R   +S R RS S  R     
Sbjct: 75  SKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS---- 130

Query: 254 RRERHRSKSPRRHRSRSRDR-------RHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKK 306
           R  RHRS+S  R +SRSR R       R R R KS    R  + R  S+S  RS+  H+ 
Sbjct: 131 RERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRT 190

Query: 307 SRR 309
             R
Sbjct: 191 RSR 193



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 42/131 (32%), Positives = 59/131 (45%), Gaps = 7/131 (5%)

Query: 180 RVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSP 239
           R+++ E   D  +  E +        R  S + R RS     K  RS +   ++SRSRS 
Sbjct: 101 RLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSR 160

Query: 240 RR-----RSRSPKRR--SPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRS 292
            R     RSR  KRR  S S  R RHR ++  R R+RSR R  + R + P        R+
Sbjct: 161 ERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRT 220

Query: 293 HSKSPERSKKS 303
            S  P R + +
Sbjct: 221 PSPPPFRGRNT 231



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 34/115 (29%), Positives = 52/115 (45%), Gaps = 4/115 (3%)

Query: 197 EEEEDEKLERVPSPDH-RRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSPRR 255
           + E D       SPD  +++   ++    R+    Y RSRSRS  R+ +S         R
Sbjct: 5   DTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSD--NEGRKHR 62

Query: 256 ERHRSKSPRRHRSRSR-DRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSRR 309
            R RSK  RRH S+ +  ++H+S   +   H S + R    S E  +  HK+  R
Sbjct: 63  SRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKER 117



 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 46/148 (31%), Positives = 64/148 (43%), Gaps = 8/148 (5%)

Query: 172 EEAE-QLEPRVSALEEDMDDVESSEEEEEEDEK----LERVPSPDHRRRSYRDLD-KPRR 225
           E++E  + PR S          S E + + D +      R  S + RR   +D   K  +
Sbjct: 25  EQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHK 84

Query: 226 SPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRH-RSRSRDRRHRSRSKSPGH 284
           S     +   S   R R  S +      +R+  +S   R H RSRSR+RRHRSRS+    
Sbjct: 85  SEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKK 144

Query: 285 HRSHRHRSHSKSPERSKKSHKKSRRGNE 312
            RS R R   KS  RS++  K   R  E
Sbjct: 145 SRS-RSRERKKSRSRSRERKKSRSRSRE 171



 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 37/119 (31%), Positives = 53/119 (44%), Gaps = 4/119 (3%)

Query: 194 SEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSP 253
           S    +E  + E       + +S    DK   S   R R + S +   R +  +R+S   
Sbjct: 63  SRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRG 122

Query: 254 RRERHRSKSPRRHRSRSRDR---RHRSRSKSPGHHRS-HRHRSHSKSPERSKKSHKKSR 308
           R         RRHRSRSR+R   R RSR +     RS  R +S S+S ER ++   +SR
Sbjct: 123 RSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSR 181



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 38/143 (26%), Positives = 63/143 (44%), Gaps = 18/143 (12%)

Query: 181 VSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPR 240
           ++A + + D +   +   + D+K E+       R S     + R     R R+S +   +
Sbjct: 1   MAASDTERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRK 60

Query: 241 RRSRSPKRRSPSPRRERHRSKSPRRHRS-----------RSRDRRHRSRSKSPGHHR--- 286
            RSRS   RS   RR   + KS ++H+S           + R+R + S +    H R   
Sbjct: 61  HRSRS---RSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKER 117

Query: 287 -SHRHRSHSKSPERSKKSHKKSR 308
            S R RSHS+S  R ++   +SR
Sbjct: 118 KSSRGRSHSRSRSRERRHRSRSR 140



 Score = 46.2 bits (108), Expect = 4e-05
 Identities = 41/156 (26%), Positives = 59/156 (37%), Gaps = 25/156 (16%)

Query: 173 EAEQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTL-RY 231
           E + L P  ++ + D       ++E+ E     R     + R   R  ++ R+S    R 
Sbjct: 7   ERDGLAPEKTSPDRD------KKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRK 60

Query: 232 RRSRSRSPR-RRSRSPKRRSPSPRRERHRSKS-----------------PRRHRSRSRDR 273
            RSRSRS   RR  S  + S   + E H  K                   R  R   +  
Sbjct: 61  HRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSS 120

Query: 274 RHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSRR 309
           R RS S+S    R HR RS  +   RS+   +K  R
Sbjct: 121 RGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSR 156



 Score = 30.0 bits (66), Expect = 2.8
 Identities = 30/108 (27%), Positives = 43/108 (39%), Gaps = 6/108 (5%)

Query: 166 QKRYVLEEAEQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRR 225
           ++R+     E+ + R  + E       S E ++      ER      RR   R   + R 
Sbjct: 132 ERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRER-----KRRIRSRSRSRSRH 186

Query: 226 SPTLRYR-RSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRD 272
               R R R+RSRS  R+ R  K R  S    R  S  P R R+ + D
Sbjct: 187 RHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMD 234


>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
           sapiens]
          Length = 375

 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 56/156 (35%), Positives = 87/156 (55%), Gaps = 15/156 (9%)

Query: 165 LQKRYVLEEAEQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPR 224
           ++  + L++  + E +  + ++   + E +++E   D+  ER+ S ++    ++   K R
Sbjct: 2   IRTNFFLKQGRRHESKDKSSKKHKSE-EHNDKEHSSDKGRERLNSSENGEDRHKR--KER 58

Query: 225 RSPTLR-YRRSRSRSPRRRSRSPKR---RSPSPRRERHRSKSPRRHRSRSRDR----RHR 276
           +S   R + RSRSR  R RSRS +R   RS S  R++ RS+S  R +SRSR R    R R
Sbjct: 59  KSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIR 118

Query: 277 SRSKSPGHHRSHRHRSHSKSPERS---KKSHKKSRR 309
           SRS+S   HR HR RS S++  RS   KK  +K RR
Sbjct: 119 SRSRSRSRHR-HRTRSRSRTRSRSRDRKKRIEKPRR 153



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 42/131 (32%), Positives = 59/131 (45%), Gaps = 7/131 (5%)

Query: 180 RVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSP 239
           R+++ E   D  +  E +        R  S + R RS     K  RS +   ++SRSRS 
Sbjct: 42  RLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSR 101

Query: 240 RR-----RSRSPKRR--SPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRS 292
            R     RSR  KRR  S S  R RHR ++  R R+RSR R  + R + P        R+
Sbjct: 102 ERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRT 161

Query: 293 HSKSPERSKKS 303
            S  P R + +
Sbjct: 162 PSPPPFRGRNT 172



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 38/122 (31%), Positives = 54/122 (44%), Gaps = 17/122 (13%)

Query: 191 VESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRS 250
           ++     E +D+  ++  S +H        DK   S   R R + S +   R +      
Sbjct: 8   LKQGRRHESKDKSSKKHKSEEHN-------DKEHSSDKGRERLNSSENGEDRHK------ 54

Query: 251 PSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSRRG 310
              R+ER  S+     RSRSR+RRHRSRS+     RS R R   KS  RS++  K   R 
Sbjct: 55  ---RKERKSSRGRSHSRSRSRERRHRSRSRERKKSRS-RSRERKKSRSRSRERKKSRSRS 110

Query: 311 NE 312
            E
Sbjct: 111 RE 112



 Score = 30.0 bits (66), Expect = 2.8
 Identities = 30/108 (27%), Positives = 43/108 (39%), Gaps = 6/108 (5%)

Query: 166 QKRYVLEEAEQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRR 225
           ++R+     E+ + R  + E       S E ++      ER      RR   R   + R 
Sbjct: 73  ERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRER-----KRRIRSRSRSRSRH 127

Query: 226 SPTLRYR-RSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRD 272
               R R R+RSRS  R+ R  K R  S    R  S  P R R+ + D
Sbjct: 128 RHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNTAMD 175


>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
          Length = 484

 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 58/178 (32%), Positives = 81/178 (45%), Gaps = 29/178 (16%)

Query: 160 IILPRLQKRYVLEEAEQLEPRV--------SALEEDMDDVESSEEEEEEDEKLERVPSPD 211
           ++ P L+     +E E+   RV        +A+E D  + +          +  R PS  
Sbjct: 205 LVSPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSS 264

Query: 212 H--------RRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSPR--RERHRSK 261
                    RRRS+      RRS + R RRS SR   RRSRS  +     +  +E+ RSK
Sbjct: 265 RHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSK 324

Query: 262 SP-------RRHRSRSRDRRHR---SRSKSPGHHRSHRHR-SHSKSPERSKKSHKKSR 308
           +P       RR RS SR+RR R   S ++SP   RS + + S S SP R KK  KK +
Sbjct: 325 TPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDK 382



 Score = 65.9 bits (159), Expect = 5e-11
 Identities = 42/138 (30%), Positives = 71/138 (51%), Gaps = 2/138 (1%)

Query: 174 AEQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDH-RRRSYRDLDKPRRSPTLRYR 232
           ++++E  +  + E    + ++ E ++++EK     S    RRR      + RRS +   R
Sbjct: 216 SKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRR 275

Query: 233 RSRSRS-PRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHR 291
           RS S+S  RRRS+SP+RR    R    RS+S  + R + ++ + + RSK+P    S   R
Sbjct: 276 RSHSKSRSRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARR 335

Query: 292 SHSKSPERSKKSHKKSRR 309
           S S S ER ++  +   R
Sbjct: 336 SRSASRERRRRRSRSGTR 353



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 47/123 (38%), Positives = 62/123 (50%), Gaps = 15/123 (12%)

Query: 191 VESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRS 250
           ++S    +E +E ++RV        +  + DK  +    R+ RSRSRS RRR+ S     
Sbjct: 210 LKSDTSSKEIEEAMKRVREAQSLISAAIEPDK--KEEKRRHSRSRSRSRRRRTPS----- 262

Query: 251 PSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRH----RSHSKSPERSKKSHKK 306
            S R  R RS+S RR  S+SR RR   RSKSP   RSH      RS S S  R KK   K
Sbjct: 263 -SSRHRRSRSRSRRRSHSKSRSRR---RSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDK 318

Query: 307 SRR 309
            ++
Sbjct: 319 EKK 321



 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 39/113 (34%), Positives = 60/113 (53%), Gaps = 13/113 (11%)

Query: 194 SEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKR---RS 250
           + ++++ED++ +R  +P     + R      R    R  RS +RSP++  RSPKR   RS
Sbjct: 310 TRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKK-PRSPKRKLSRS 368

Query: 251 PSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKS 303
           PSPRR + + K   + + RSRD R RS SK        + +S  K  +R +KS
Sbjct: 369 PSPRRHK-KEKKKDKDKERSRDERERSTSK--------KKKSKDKEKDRERKS 412



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 26/66 (39%), Positives = 34/66 (51%), Gaps = 8/66 (12%)

Query: 246 PKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHK 305
           P ++    R  R RS+S RR R+ S  R  RSRS+S       R RSHSKS  R +    
Sbjct: 239 PDKKEEKRRHSRSRSRS-RRRRTPSSSRHRRSRSRS-------RRRSHSKSRSRRRSKSP 290

Query: 306 KSRRGN 311
           + RR +
Sbjct: 291 RRRRSH 296



 Score = 36.2 bits (82), Expect = 0.038
 Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 18/107 (16%)

Query: 193 SSEEEEEEDEKLERVPSPD-HRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSP 251
           S ++      KL R PSP  H++   +D DK            RSR  R RS S K++S 
Sbjct: 354 SPKKPRSPKRKLSRSPSPRRHKKEKKKDKDK-----------ERSRDERERSTSKKKKSK 402

Query: 252 SPRRERHR-SKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSP 297
              ++R R S+S +  +  +RD     +      + S + +   K P
Sbjct: 403 DKEKDRERKSESDKDVKQVTRDYDEEEQG-----YDSEKEKKEEKKP 444


>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
           sapiens]
          Length = 1031

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 48/108 (44%), Positives = 60/108 (55%), Gaps = 8/108 (7%)

Query: 211 DHRRRSYRDLDKPR-RSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSR 269
           D RR   RD D+ R RS +   RRSRSR  R+R R  + R     RER RS+S  R RSR
Sbjct: 36  DDRRSRSRDRDRRRERSRSRDKRRSRSRD-RKRLRRSRSRERDRSRERRRSRSRDRRRSR 94

Query: 270 SRDRRHRSRSKSPGHHRSHRHRSHSKSPER-----SKKSHKKSRRGNE 312
           SR R  RSRS SPG ++S +  + S+S E+     S K  KK +   E
Sbjct: 95  SRSRGRRSRSSSPG-NKSKKTENRSRSKEKTDGGESSKEKKKDKDDKE 141



 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 47/97 (48%), Positives = 56/97 (57%), Gaps = 9/97 (9%)

Query: 214 RRSYRDLDKPRRSPTLRYRRSRSRS-PRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRD 272
           +RS R  D+  RS     RR RSRS  +RRSRS  R+     R R R +S  R RSRSRD
Sbjct: 30  KRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRD 89

Query: 273 RRHRSRSKSPGHHRSHRHRSHSKSP-ERSKKSHKKSR 308
           RR RSRS+S G       RS S SP  +SKK+  +SR
Sbjct: 90  RR-RSRSRSRG------RRSRSSSPGNKSKKTENRSR 119



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 35/81 (43%), Positives = 42/81 (51%), Gaps = 4/81 (4%)

Query: 233 RSRSRSP--RRRSRSPKRRSPSPRRERHRSKSPRR--HRSRSRDRRHRSRSKSPGHHRSH 288
           RSRSRSP  +R  R   RRS S  R+R R +S  R   RSRSRDR+   RS+S    RS 
Sbjct: 21  RSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRERDRSR 80

Query: 289 RHRSHSKSPERSKKSHKKSRR 309
             R       R  +S  + RR
Sbjct: 81  ERRRSRSRDRRRSRSRSRGRR 101



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 35/88 (39%), Positives = 43/88 (48%), Gaps = 9/88 (10%)

Query: 230 RYRRSRSRSPRRRSRSPKRRSPSP--------RRERHRSKSPRRHRSRSRDRRHRSRSKS 281
           R+ R RS S  R     + RSPS         RR R R +  RR RSRSRD+R RSRS+ 
Sbjct: 6   RHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKR-RSRSRD 64

Query: 282 PGHHRSHRHRSHSKSPERSKKSHKKSRR 309
               R  R R   +S ER +   +  RR
Sbjct: 65  RKRLRRSRSRERDRSRERRRSRSRDRRR 92



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 29/84 (34%), Positives = 38/84 (45%), Gaps = 3/84 (3%)

Query: 232 RRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRH---RSRSKSPGHHRSH 288
           R  R RS  R     + RS SP  +R +    RR RSR RDRR    RSR K     R  
Sbjct: 6   RHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDR 65

Query: 289 RHRSHSKSPERSKKSHKKSRRGNE 312
           +    S+S ER +   ++  R  +
Sbjct: 66  KRLRRSRSRERDRSRERRRSRSRD 89


>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
          Length = 344

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 53/128 (41%), Positives = 68/128 (53%), Gaps = 12/128 (9%)

Query: 182 SALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRR 241
           S ++  +D ++ +E        +E  P   HRR SY       RS +   RRSRSRS  R
Sbjct: 157 SDMKRALDKLDGTEINGRNIRLIEDKPRTSHRR-SYSG----SRSRSRSRRRSRSRS--R 209

Query: 242 RSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKS-PGHHRSHRHRSHSKSPERS 300
           RS   + RS S  R R RS+S  R RSRS+ R+ RS+SKS P   R     SHS S  RS
Sbjct: 210 RSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRG----SHSHSRSRS 265

Query: 301 KKSHKKSR 308
           K  ++KSR
Sbjct: 266 KDEYEKSR 273



 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 46/93 (49%), Positives = 53/93 (56%), Gaps = 6/93 (6%)

Query: 221 DKPRRSPTLRYRRSRSRS-PRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRS 279
           DKPR S    Y  SRSRS  RRRSRS  RRS    R R RS S  R RSRSR +  RSRS
Sbjct: 181 DKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSS---RSRSRSISKSRSRSRSRSKG-RSRS 236

Query: 280 KSPGHHRSHRHRSHSKSPERSKKSHKKSRRGNE 312
           +S G     + +S  KS +R   SH +SR  +E
Sbjct: 237 RSKGRKSRSKSKSKPKS-DRGSHSHSRSRSKDE 268



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 31/78 (39%), Positives = 40/78 (51%), Gaps = 6/78 (7%)

Query: 231 YRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRS--- 287
           Y +SRSRS   RSRSPK       + + RS+S  R  S       ++RS SP   R+   
Sbjct: 269 YEKSRSRS---RSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRATSR 325

Query: 288 HRHRSHSKSPERSKKSHK 305
            R RS SKS  RS+ S +
Sbjct: 326 SRSRSRSKSRSRSRSSSR 343



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 45/140 (32%), Positives = 58/140 (41%), Gaps = 24/140 (17%)

Query: 193 SSEEEEEEDEKLERVPSPDHRRRSYRDLDKPR-RSPTLRYRRSRSRSPRRRSRSPKRRSP 251
           S         +  R  S    R   R + K R RS +    RSRSRS  R+SRS  +  P
Sbjct: 192 SGSRSRSRSRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKP 251

Query: 252 SPRRERH---RSKSP---RRHRSRSRDR----------------RHRSRSKSPGHHRSHR 289
              R  H   RS+S     + RSRSR R                R +SRS SP      +
Sbjct: 252 KSDRGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSK 311

Query: 290 HRSHSKSPER-SKKSHKKSR 308
            RS S  P+R + +S  +SR
Sbjct: 312 ARSVSPPPKRATSRSRSRSR 331



 Score = 36.2 bits (82), Expect = 0.038
 Identities = 28/82 (34%), Positives = 38/82 (46%), Gaps = 5/82 (6%)

Query: 194 SEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRS---PKRRS 250
           S++E E+     R  SP    +   D+    RS +     S    P  ++RS   P +R+
Sbjct: 265 SKDEYEKSRSRSRSRSPKENGKG--DIKSKSRSRSQSRSNSPLPVPPSKARSVSPPPKRA 322

Query: 251 PSPRRERHRSKSPRRHRSRSRD 272
            S  R R RSKS  R RS SRD
Sbjct: 323 TSRSRSRSRSKSRSRSRSSSRD 344


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 59/196 (30%), Positives = 79/196 (40%), Gaps = 55/196 (28%)

Query: 165 LQKRYVLEEAEQLEPRVSALEEDMD-DVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKP 223
           L+K  + +   + E   S  ++D D D    EE+E   EK ER  SP  RR+S     + 
Sbjct: 126 LKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSP-RRRKSRSPSPRR 184

Query: 224 RRSPTLRYR-RSRSRSPRRRSRS------------------------------------- 245
           R SP  R R RS SRSPR R++S                                     
Sbjct: 185 RSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDI 244

Query: 246 ---------PKRRSPSPRRERHRSKSPRRHRSRSRDR---RHRSRSKSPGH---HRSHRH 290
                    P+ + PSP +   + K   + R RSR R   R R+RS+SP H    R HR 
Sbjct: 245 LKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRS 304

Query: 291 RSHSKSPERSKKSHKK 306
           RS S SP R     ++
Sbjct: 305 RSRSYSPRRRPSPRRR 320



 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 51/127 (40%), Positives = 65/127 (51%), Gaps = 11/127 (8%)

Query: 192 ESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYR-RSRSRSPRRRSRSPKRRS 250
           ++S++E+E+++   R  S    R   R        P  R+R RSRS SPRRR  SP+RR 
Sbjct: 263 KNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRP-SPRRR- 320

Query: 251 PSPRRE---RHRSKSPRRHRSRS--RDRRHRSRSKSPGHHRSHRHRSHS---KSPERSKK 302
           PSPRR    R     PR  RSRS  R RR  S S S     S   RS S   K P+R+  
Sbjct: 321 PSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSS 380

Query: 303 SHKKSRR 309
             +K+RR
Sbjct: 381 PPRKTRR 387



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 40/129 (31%), Positives = 65/129 (50%), Gaps = 13/129 (10%)

Query: 176 QLEPRVSALEEDMDDVESSEEEEEEDE-KLERVPSPDHRRRSYRDLDKPRRSPTLRYRRS 234
           +L P + + +E++  + S+  E +++E K  ++          +D DK +R         
Sbjct: 104 ELWPLLLSAQENIAGIPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRD-------- 155

Query: 235 RSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHS 294
             +  +  SR  + RS SPRR + RS SPRR  S  R  R RS S+SP H    + RS S
Sbjct: 156 --KEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRT--KSRSPS 211

Query: 295 KSPERSKKS 303
            +PE+ +K+
Sbjct: 212 PAPEKKEKT 220



 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 43/113 (38%), Positives = 57/113 (50%), Gaps = 14/113 (12%)

Query: 206 RVPSPDHRRRSYRDLDKPRR-SPTLRYRRSRSRSPRRRSRSP-----KRRSPSPRRERHR 259
           R PSP  RRRS      PRR SP ++ R S S  P+RR+ SP     +R SPSP  +R  
Sbjct: 580 RTPSPPPRRRS----PSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRV 635

Query: 260 SKSPRRHRSRSRDRRHRSRSKSPGHHRSH---RHRSHSKSPERSKKSHKKSRR 309
           S SP   +  S   + RS S S  H +     R    ++SP+ +K+ H  S R
Sbjct: 636 SHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKR-HSPSPR 687



 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 44/138 (31%), Positives = 64/138 (46%), Gaps = 8/138 (5%)

Query: 178 EPRVSALEEDMDDVESSEE--EEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSR 235
           EP V   E  + +  S+ +  +  + E +     P   + S ++ +K +  P  R  RS+
Sbjct: 225 EPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSR-SRSK 283

Query: 236 SRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHR--SHRHRSH 293
           SRS R RSRSP    P  RR R RS+S    R  S  RR   R ++P        RHR  
Sbjct: 284 SRS-RTRSRSPSHTRPR-RRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHR-R 340

Query: 294 SKSPERSKKSHKKSRRGN 311
           S+SP R ++    S  G+
Sbjct: 341 SRSPVRRRRRSSASLSGS 358



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 39/113 (34%), Positives = 48/113 (42%), Gaps = 9/113 (7%)

Query: 208 PSPDHRRRSYRDLDKPRRSPTLR---YRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPR 264
           P P  RRRS      PRR  T      RR+ S  PRRRS SP+R SP  +R    S  P+
Sbjct: 552 PPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPK 611

Query: 265 RHRSRSRDRRHRSRSKSP------GHHRSHRHRSHSKSPERSKKSHKKSRRGN 311
           R  +       R  S SP       H    + RS   +  RS     K R+G+
Sbjct: 612 RRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGS 664



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 30/74 (40%), Positives = 37/74 (50%), Gaps = 5/74 (6%)

Query: 234 SRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSH 293
           S  +    + +  K    S R +R RS+SPRR +SRS   R RS   SP   R  R RSH
Sbjct: 143 SMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRS---SPV--RRERKRSH 197

Query: 294 SKSPERSKKSHKKS 307
           S+SP    KS   S
Sbjct: 198 SRSPRHRTKSRSPS 211



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 47/137 (34%), Positives = 60/137 (43%), Gaps = 22/137 (16%)

Query: 191 VESSEEEEEEDEKLERVPSPDHRRRSYR-------DLDKPRRSPTLRYRRSRSRSP---R 240
           VE SE EE++  K+    S   RR+  R       D      S   R +RS  ++    R
Sbjct: 460 VELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGR 519

Query: 241 RRSRSPKRR-SPSPRRERHRSKSPRRHRSRSRD----RRHRSRSKSPGHHRSH------R 289
           RR  SP R  SPSPR+ R +  SPR  R RS      RR RS S +P   R        R
Sbjct: 520 RRRHSPSRSASPSPRK-RQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPR 578

Query: 290 HRSHSKSPERSKKSHKK 306
            R+ S  P R   S ++
Sbjct: 579 RRTPSPPPRRRSPSPRR 595



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 40/131 (30%), Positives = 58/131 (44%), Gaps = 18/131 (13%)

Query: 185 EEDMDDVESSEEEEEEDEKLERVPSPD-HRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRS 243
           ++   D  SS   E+E  K   V + +  RRR +        SP  R + +  R  RRRS
Sbjct: 490 QQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRS 549

Query: 244 RSP----KRRSPSPRRERHRSKSPRRHRSRSRDRRHRS-------RSKSPGHHRSHRHRS 292
            SP    +RRSPSP      +  PRR R+ +   R R+       RS SP  +     R 
Sbjct: 550 PSPPPTRRRRSPSP------APPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRR 603

Query: 293 HSKSPERSKKS 303
           +S SP   +++
Sbjct: 604 YSPSPPPKRRT 614



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 40/118 (33%), Positives = 53/118 (44%), Gaps = 23/118 (19%)

Query: 206 RVPSPDHRRRSYRDLDKPRRSPTL-RYRRSRSRSPRRR------------SRSPKRRSPS 252
           R PSP  RR S R    PRR P   R+RRSRS   RRR            S S + RSP 
Sbjct: 313 RRPSP-RRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPP 371

Query: 253 PRRERHRSKSPRRHRSRSRD-----RRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHK 305
            +  +  S  PR+ R  S       RRHR    +    ++     HS +P++S ++ K
Sbjct: 372 KKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTR----HSPTPQQSNRTRK 425



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 38/115 (33%), Positives = 52/115 (45%), Gaps = 15/115 (13%)

Query: 208 PSPDHRRRSYRDLDKPRR----SPTLRYRRSRSRSPRRRSRSP--KRRSPSPRRERHRSK 261
           PSP  +RR+      P+R    SP  + R S S  P++RS SP  KRRSPS   +  +  
Sbjct: 606 PSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRS-SPVTKRRSPSLSSKHRKGS 664

Query: 262 SP----RRHRSRSRDRRH----RSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSR 308
           SP    R  RS   ++RH    R R+           R  S SP+R +     +R
Sbjct: 665 SPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTR 719



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 41/115 (35%), Positives = 53/115 (46%), Gaps = 16/115 (13%)

Query: 208 PSPDHRRR-SYRDLDKPR-------RSPTLRYRRSRSRSPRR---RSRSP---KRRSPSP 253
           PSP  +RR S+    K R       RSP+L  +  +  SP R    +RSP   KR SPSP
Sbjct: 627 PSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSP 686

Query: 254 R-RERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKS 307
           R R    S SP   R  +     R +S SP   R  R  S +  P++ KK+   S
Sbjct: 687 RPRAPQTSSSPPPVRRGASSSPQRRQSPSPS-TRPIRRVSRTPEPKKIKKAASPS 740



 Score = 29.3 bits (64), Expect = 4.7
 Identities = 30/121 (24%), Positives = 49/121 (40%), Gaps = 26/121 (21%)

Query: 200 EDEKLERV--PSPDHRRR--SYRDLD--------KPRRSPTLRYRRSRSRSPRRRSRSPK 247
           E +K+++   PSP   RR  S R +         KP   P+    +S S +        K
Sbjct: 729 EPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKK 788

Query: 248 RRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKS 307
            +SP+P      S SP R+  +    + + + K   H +  +H+ H        K HKK 
Sbjct: 789 AKSPTP------SPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKH--------KKHKKE 834

Query: 308 R 308
           +
Sbjct: 835 K 835


>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
          Length = 715

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 45/144 (31%), Positives = 67/144 (46%), Gaps = 24/144 (16%)

Query: 186 EDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPR-----RSPTLRYRRSRSRSPR 240
           ++ D  +     +E D +  R PS + + R  R   K R     RSP+   +R +SRSP 
Sbjct: 481 KERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPN 540

Query: 241 RRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDR-----RHRSRSKSPGHHRSHRHRSHSK 295
           +     + RSPS  RE  +S+SP + R R R R     R R +S+S    R H   S S+
Sbjct: 541 KERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDH---SRSR 597

Query: 296 SPER-----------SKKSHKKSR 308
           SP +            +K+H +SR
Sbjct: 598 SPNKQSGYSRPRASSKEKAHSRSR 621



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 41/127 (32%), Positives = 63/127 (49%), Gaps = 6/127 (4%)

Query: 192 ESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPR-----RSPTLRYRRSRSRSPRRRSRSP 246
           +S    +E D +  R PS + +RR  R  +K R     RSP+      +SRSP +     
Sbjct: 511 QSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRR 570

Query: 247 KRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSKK-SHK 305
           + RSPS  RER +S+S    R  SR R    +S       S + ++HS+S   SK+ +H 
Sbjct: 571 RWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHS 630

Query: 306 KSRRGNE 312
           +SR  ++
Sbjct: 631 QSRTSSK 637



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 49/145 (33%), Positives = 66/145 (45%), Gaps = 12/145 (8%)

Query: 172 EEAEQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPR---RSPT 228
           +E      R S+ E D     S  +E    +        DH R    +  + R   RSP 
Sbjct: 361 KERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPY 420

Query: 229 LRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDR-----RHRSRSKSPG 283
               RSRSRSP +     + RSP   R+R RS+SP + R  SR R     R RSRS+SP 
Sbjct: 421 KARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPS 480

Query: 284 HHRSHRHRSHSKSPERSKKSHKKSR 308
             R H   S   SP + ++ H++SR
Sbjct: 481 KERDH---SQLGSPSK-ERDHRRSR 501



 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 48/131 (36%), Positives = 62/131 (47%), Gaps = 16/131 (12%)

Query: 189 DDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPR-----RSPTLRYRRSRSRSPRRRS 243
           D   S    +  D    R P     R   R  +K R     RSP     RSRSRSP +  
Sbjct: 400 DHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKAR 459

Query: 244 RSPKRRSPSPRRERHRSKSPRRHR------SRSRDRRHRSRSKSPGHHRSHRHRSHSKSP 297
              + RSP+  R+R RS+SP + R      S S++R HR RS+SP   R  R +S S S 
Sbjct: 460 DHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHR-RSRSPSKERQCR-QSRSSSK 517

Query: 298 ERSKKSHKKSR 308
           ER    H++SR
Sbjct: 518 ER---DHRRSR 525



 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 48/123 (39%), Positives = 62/123 (50%), Gaps = 30/123 (24%)

Query: 214 RRSYRDLDKPR-RSPTLRYRRSRSRSP-----RRRSRSPKRR-------SPSPRRERHRS 260
           R  Y+  D+ R RSP      SRSRSP     R RSRSP +        SPS  R+  RS
Sbjct: 441 RSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRS 500

Query: 261 KSP------RRHRSRSRDRRHRSRSKSPGHHRSHRH---------RSHSKSPERSKKSHK 305
           +SP      R+ RS S++R HR RS+SP   R  R          RS S+SP   ++ H+
Sbjct: 501 RSPSKERQCRQSRSSSKERDHR-RSRSPSKERQRRQSRSPNKERDRSQSRSPS-EEREHR 558

Query: 306 KSR 308
           +SR
Sbjct: 559 QSR 561



 Score = 58.5 bits (140), Expect = 7e-09
 Identities = 42/134 (31%), Positives = 59/134 (44%), Gaps = 11/134 (8%)

Query: 189 DDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRR-----SPTLRYRRSRSRSPRRRS 243
           D   S    +  D    R P+    R   R   K R      SP+      RSRSP +  
Sbjct: 448 DRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKER 507

Query: 244 RSPKRRSPSPRRERHRSKSPRRHRSRSRDR-----RHRSRSKSPGHHRSHRHRSHSKSPE 298
           +  + RS S  R+  RS+SP + R R + R     R RS+S+SP   R HR +S S S E
Sbjct: 508 QCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHR-QSRSPSKE 566

Query: 299 RSKKSHKKSRRGNE 312
           R ++  +   +  E
Sbjct: 567 RDRRRWRSPSKERE 580



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 46/137 (33%), Positives = 62/137 (45%), Gaps = 20/137 (14%)

Query: 189 DDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKR 248
           D   S    +E D      PS +   R  R   K R+      R+SRS S  R  R  + 
Sbjct: 472 DRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQC-----RQSRSSSKERDHR--RS 524

Query: 249 RSPSPRRERHRSKSPRRHRSRSRDR-----RHRSRSKSPGHHRSHRH-RSHSKSPER--- 299
           RSPS  R+R +S+SP + R RS+ R     R   +S+SP   R  R  RS SK  ER   
Sbjct: 525 RSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQS 584

Query: 300 ----SKKSHKKSRRGNE 312
                ++ H +SR  N+
Sbjct: 585 RSSSEERDHSRSRSPNK 601



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 38/134 (28%), Positives = 59/134 (44%), Gaps = 8/134 (5%)

Query: 172 EEAEQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPR-----RS 226
           +E ++ + R    E D     S  EE E   +  R PS +  RR +R   K R     RS
Sbjct: 529 KERQRRQSRSPNKERDRSQSRSPSEERE--HRQSRSPSKERDRRRWRSPSKERERRQSRS 586

Query: 227 PTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHR 286
            +     SRSRSP ++S   + R+ S  +   RS++P +  + S+ R   S+   P    
Sbjct: 587 SSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRT-SSKESDPSQST 645

Query: 287 SHRHRSHSKSPERS 300
             R     +SP R+
Sbjct: 646 VPRSPDWKRSPTRT 659



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 41/111 (36%), Positives = 56/111 (50%), Gaps = 12/111 (10%)

Query: 209 SPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRER--HRSKSPRRH 266
           S  H R S ++ D  R S + R    RS+S     +    RS SP + R   RS+SP + 
Sbjct: 364 SHSHSRSSSKERDH-RGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKA 422

Query: 267 RSRSRDR-----RHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSRRGNE 312
           R RSR R     R  SRS+SP      R RS S+SP ++ + H +SR  N+
Sbjct: 423 RDRSRSRSPNKARDCSRSRSP---YKARDRSRSRSPNKA-RDHSRSRSPNK 469



 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 41/133 (30%), Positives = 60/133 (45%), Gaps = 12/133 (9%)

Query: 185 EEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSR-SPRRRS 243
           +E  D+   S   + +      +PS   R +SY   +   R  +     +RSR     +S
Sbjct: 228 KEKSDNPSPSSSRKVKSYGQMIIPS---REKSYSPTEMSSRVKSYNQASTRSRPQSHSQS 284

Query: 244 RSPKR-RSPSPRR--ERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERS 300
           RSP+R RS S +R   R RS S +R+ SR+R R  +      G H   R  S  KS  +S
Sbjct: 285 RSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQS 344

Query: 301 K-----KSHKKSR 308
           +     +SH  SR
Sbjct: 345 RTPRRGRSHNWSR 357



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 37/113 (32%), Positives = 51/113 (45%), Gaps = 11/113 (9%)

Query: 208 PSPDHRRRSYRDLDKPRRSPTLRYR-RSRSRSPRRRSRSPKRRSPSP--------RRERH 258
           PS     +S      P   P+ R R RS++R+P R S   +    S         RR  H
Sbjct: 59  PSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCHQRRGTH 118

Query: 259 -RSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSRRG 310
            R ++P R  SRS  +R  SR+ +PG  R+H  R    S  R+  S +K  RG
Sbjct: 119 SRGRTPGRRGSRS-SKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRG 170



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 33/84 (39%), Positives = 44/84 (52%), Gaps = 12/84 (14%)

Query: 225 RSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKS--PRRHRSRSRDR-----RHRS 277
           R+P+     S SRS  +      R S SPR+E  RS+S  P + R  SR R     R RS
Sbjct: 357 RNPSKERSHSHSRSSSKER--DHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRS 414

Query: 278 RSKSPGHHRSHRHRSHSKSPERSK 301
           RS+SP      R RS S+SP +++
Sbjct: 415 RSRSP---YKARDRSRSRSPNKAR 435



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 35/105 (33%), Positives = 50/105 (47%), Gaps = 11/105 (10%)

Query: 215 RSYRDLDKPRRSPTLRYRRSR--SRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRD 272
           RS+       +S T R  RS   SR+P +       RS S  R+   S SPR+   RS+ 
Sbjct: 333 RSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQS 392

Query: 273 -----RRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSRRGNE 312
                +R  SRS+SP      R RS S+SP ++ +   +SR  N+
Sbjct: 393 GSPNKQRDHSRSRSP---NKARDRSRSRSPYKA-RDRSRSRSPNK 433



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 45/173 (26%), Positives = 73/173 (42%), Gaps = 31/173 (17%)

Query: 160 IILPRLQKRYVLEEAEQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRD 219
           +I+P  +K Y      ++  RV +  +      S  +   +     R  S   +R   R 
Sbjct: 248 MIIPSREKSY---SPTEMSSRVKSYNQA--STRSRPQSHSQSRSPRRSRSGSQKRTHSRV 302

Query: 220 LDKPRRSPTLRYRRSRSRSPRRRS------RSPKRRSPSPRRERHRSKSPRRHRSRSRDR 273
                RS + +   SR+RS  R+       R  + RS S  + +++S++PRR RS +  R
Sbjct: 303 -----RSHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSR 357

Query: 274 -----RHRSRSKSPGHHRSHR---------HRSHSKSPERSKKSHKKSRRGNE 312
                R  S S+S    R HR          RS S SP + ++ H +SR  N+
Sbjct: 358 NPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNK-QRDHSRSRSPNK 409



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 20/83 (24%), Positives = 33/83 (39%)

Query: 225 RSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGH 284
           R+  +    S+S       R+P  R  S  R R ++++P R  + +R  +    S    H
Sbjct: 53  RNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKASDVRCH 112

Query: 285 HRSHRHRSHSKSPERSKKSHKKS 307
            R   H        R  +S K+S
Sbjct: 113 QRRGTHSRGRTPGRRGSRSSKRS 135


>gi|41393554 LUC7-like isoform b [Homo sapiens]
          Length = 371

 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 60/192 (31%), Positives = 87/192 (45%), Gaps = 23/192 (11%)

Query: 126 DYRKIKSQNRNGEFEL---MHVDEFIDELLHSERVCDIILPRL-----QKRYVLEEAEQL 177
           +  K++++ +  E E    M    F  + L   RVC++    L      +R       +L
Sbjct: 158 EVEKVRAKKKEAEEEYRNSMPASSFQQQKL---RVCEVCSAYLGLHDNDRRLADHFGGKL 214

Query: 178 EPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSR 237
                 + E +D +  +  E++E    +R+   + R R  R L +   S T   RRSRSR
Sbjct: 215 HLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREER-LSRRSGSRTRDRRRSRSR 273

Query: 238 SPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSK--SPGHHRSHRHRSHSK 295
             RR      RRS S  RER +     R RSR R RRHRSRS+  S GH R+ R RS   
Sbjct: 274 DRRR------RRSRSTSRERRKLS---RSRSRDRHRRHRSRSRSHSRGHRRASRDRSAKY 324

Query: 296 SPERSKKSHKKS 307
              R + S ++S
Sbjct: 325 KFSRERASREES 336



 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 38/99 (38%), Positives = 49/99 (49%), Gaps = 1/99 (1%)

Query: 211 DHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRS 270
           D  R++  +  + R    LR R  R R  R   RS  R +   RR R R +  RR RS S
Sbjct: 226 DQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSR-TRDRRRSRSRDRRRRRSRSTS 284

Query: 271 RDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSRR 309
           R+RR  SRS+S   HR HR RS S S    + S  +S +
Sbjct: 285 RERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323



 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 45/133 (33%), Positives = 60/133 (45%), Gaps = 13/133 (9%)

Query: 170 VLEEAEQLEPRVSALEEDMD-DVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPT 228
           + E+ +QL   V+  +E  + D     EE E +E+L R       R   R  D+ RRS +
Sbjct: 221 IREKLDQLRKTVAEKQEKRNQDRLRRREEREREERLSR-------RSGSRTRDR-RRSRS 272

Query: 229 LRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSH 288
              RR RSRS  R  R   R     R  RHRS+S    RS SR  R  SR +S  +  S 
Sbjct: 273 RDRRRRRSRSTSRERRKLSRSRSRDRHRRHRSRS----RSHSRGHRRASRDRSAKYKFSR 328

Query: 289 RHRSHSKSPERSK 301
              S  +S E  +
Sbjct: 329 ERASREESWESGR 341


>gi|42741684 zinc finger protein 265 isoform 1 [Homo sapiens]
          Length = 330

 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 49/149 (32%), Positives = 71/149 (47%), Gaps = 23/149 (15%)

Query: 182 SALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDK----------PRRSPTLRY 231
           +++ ++++D ES  EEE+EDE L +    +       DL K            +  + R 
Sbjct: 142 ASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRR 201

Query: 232 RRSRSRSPRRRSRSPKRRSPSPRRERHRSKS------------PRRHRSRSRDRRHRSRS 279
            RS+SRS   RS S +  SPS  R R RS+S              R RSRSR  + RS S
Sbjct: 202 SRSKSRSSHSRSSS-RSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSS 260

Query: 280 KSPGHHRSHRHRSHSKSPERSKKSHKKSR 308
           +S     S R RS+S S    +++ K+SR
Sbjct: 261 RSHRGSSSPRKRSYSSSSSSPERNRKRSR 289



 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 55/151 (36%), Positives = 69/151 (45%), Gaps = 17/151 (11%)

Query: 172 EEAEQLEPRVSALEEDMDDVESSE------EEEEEDEKLERVPSPDHRRRSYRDLDKPRR 225
           +E E L       +ED DD + S+      EEE+ ++K     S    R S+        
Sbjct: 159 DEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSS 218

Query: 226 SPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSK------SPRRHRSRS--RDRRHRS 277
           SP+    RSRSRS  R S S + RS S  RER RS+      S R HR  S  R R + S
Sbjct: 219 SPSSSRSRSRSRS--RSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSS 276

Query: 278 RSKSPGHHRSHRHRSHSKSPERSKKSHKKSR 308
            S SP  +R  R RS S S    KK   +SR
Sbjct: 277 SSSSPERNRK-RSRSRSSSSGDRKKRRTRSR 306


>gi|42741682 zinc finger protein 265 isoform 2 [Homo sapiens]
          Length = 320

 Score = 63.5 bits (153), Expect = 2e-10
 Identities = 49/149 (32%), Positives = 71/149 (47%), Gaps = 23/149 (15%)

Query: 182 SALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDK----------PRRSPTLRY 231
           +++ ++++D ES  EEE+EDE L +    +       DL K            +  + R 
Sbjct: 142 ASILKEVEDKESEGEEEDEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRR 201

Query: 232 RRSRSRSPRRRSRSPKRRSPSPRRERHRSKS------------PRRHRSRSRDRRHRSRS 279
            RS+SRS   RS S +  SPS  R R RS+S              R RSRSR  + RS S
Sbjct: 202 SRSKSRSSHSRSSS-RSSSPSSSRSRSRSRSRSSSSSQSRSRSSSRERSRSRGSKSRSSS 260

Query: 280 KSPGHHRSHRHRSHSKSPERSKKSHKKSR 308
           +S     S R RS+S S    +++ K+SR
Sbjct: 261 RSHRGSSSPRKRSYSSSSSSPERNRKRSR 289



 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 55/151 (36%), Positives = 69/151 (45%), Gaps = 17/151 (11%)

Query: 172 EEAEQLEPRVSALEEDMDDVESSE------EEEEEDEKLERVPSPDHRRRSYRDLDKPRR 225
           +E E L       +ED DD + S+      EEE+ ++K     S    R S+        
Sbjct: 159 DEDEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSS 218

Query: 226 SPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSK------SPRRHRSRS--RDRRHRS 277
           SP+    RSRSRS  R S S + RS S  RER RS+      S R HR  S  R R + S
Sbjct: 219 SPSSSRSRSRSRS--RSSSSSQSRSRSSSRERSRSRGSKSRSSSRSHRGSSSPRKRSYSS 276

Query: 278 RSKSPGHHRSHRHRSHSKSPERSKKSHKKSR 308
            S SP  +R  R RS S S    KK   +SR
Sbjct: 277 SSSSPERNRK-RSRSRSSSSGDRKKRRTRSR 306


>gi|24307919 small nuclear ribonucleoprotein 27kDa (U4/U6.U5) [Homo
           sapiens]
          Length = 155

 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 41/80 (51%), Positives = 47/80 (58%), Gaps = 9/80 (11%)

Query: 233 RSRSRSPRR---RSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHR 289
           RSRSRSPRR   RSRS  R     RRER RS+   R RSRSR   HR RS+SP      R
Sbjct: 3   RSRSRSPRRERRRSRSTSRERERRRRERSRSRERDRRRSRSRS-PHRRRSRSP-----RR 56

Query: 290 HRSHSKSPERSKKSHKKSRR 309
           HRS S SP R K+   + ++
Sbjct: 57  HRSTSPSPSRLKERRDEEKK 76



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 36/82 (43%), Positives = 43/82 (52%), Gaps = 2/82 (2%)

Query: 225 RSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRD-RRHRSRSKSPG 283
           RSP    RRSRS S R R R  + RS S  R+R RS+S   HR RSR  RRHRS S SP 
Sbjct: 7   RSPRRERRRSRSTS-RERERRRRERSRSRERDRRRSRSRSPHRRRSRSPRRHRSTSPSPS 65

Query: 284 HHRSHRHRSHSKSPERSKKSHK 305
             +  R     ++ E   K  +
Sbjct: 66  RLKERRDEEKKETKETKSKERQ 87



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 36/101 (35%), Positives = 42/101 (41%), Gaps = 19/101 (18%)

Query: 206 RVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRR 265
           R  SP   RR  R   + R     R RR RSRS  R  R  + RSP     R RS+SPRR
Sbjct: 5   RSRSPRRERRRSRSTSRERE----RRRRERSRSRERDRRRSRSRSP----HRRRSRSPRR 56

Query: 266 HRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKK 306
           H           RS SP   R    R   K   +  KS ++
Sbjct: 57  H-----------RSTSPSPSRLKERRDEEKKETKETKSKER 86



 Score = 37.0 bits (84), Expect = 0.023
 Identities = 31/82 (37%), Positives = 40/82 (48%), Gaps = 13/82 (15%)

Query: 194 SEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRR-RSRSPKRRSPS 252
           S   E E  + ER  S +  RR  R      RSP     R RSRSPRR RS SP   SPS
Sbjct: 18  STSRERERRRRERSRSRERDRRRSRS-----RSP----HRRRSRSPRRHRSTSP---SPS 65

Query: 253 PRRERHRSKSPRRHRSRSRDRR 274
             +ER   +      ++S++R+
Sbjct: 66  RLKERRDEEKKETKETKSKERQ 87


>gi|89276756 serine/threonine-protein kinase PRP4K [Homo sapiens]
          Length = 1007

 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 51/103 (49%), Positives = 58/103 (56%), Gaps = 16/103 (15%)

Query: 194 SEEEEEEDEKLERVPSPDHRRR----SYRDLDKP-----RRSPTLRYRRS----RSRSPR 240
           S E +  + +  R+ SP  R R    S R+  K      R SPT R  RS    RSRSP 
Sbjct: 396 SLERKRREPERRRLSSPRTRPRDDILSRRERSKDASPINRWSPTRRRSRSPIRRRSRSPL 455

Query: 241 RRSRSPKRRSPSPRR--ERHRSKSPRRHRSRSR-DRRHRSRSK 280
           RRSRSP+RRS SPRR     RS+S  R RSRSR  RR RSRSK
Sbjct: 456 RRSRSPRRRSRSPRRRDRGRRSRSRLRRRSRSRGGRRRRSRSK 498



 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 51/113 (45%), Positives = 57/113 (50%), Gaps = 18/113 (15%)

Query: 200 EDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSP-------RRRSRSP-KRRSP 251
           +   LER      RRR      +PR     R  RS+  SP       RRRSRSP +RRS 
Sbjct: 393 KSRSLERKRREPERRRLSSPRTRPRDDILSRRERSKDASPINRWSPTRRRSRSPIRRRSR 452

Query: 252 SPRRERHRSKSPRRHRSRS---RDRRHRSRSKSPGHHRS---HRHRSHSKSPE 298
           SP R   RS+SPRR RSRS   RDR  RSRS+     RS    R RS SK  E
Sbjct: 453 SPLR---RSRSPRR-RSRSPRRRDRGRRSRSRLRRRSRSRGGRRRRSRSKVKE 501



 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 50/145 (34%), Positives = 63/145 (43%), Gaps = 26/145 (17%)

Query: 190 DVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRS--PTLRYRRSRSRSPRRRSRSPK 247
           D  S +E      +  R  SP  R  S +  DK RRS  P L  RRS+      R+ SP 
Sbjct: 332 DASSGKENRSPSRRPGR--SPKRRSLSPKPRDKSRRSRSPLLNDRRSKQSKSPSRTLSPG 389

Query: 248 RRSPSPRRERHRSKSPRRH----RSRSRD----RRHRS--------------RSKSPGHH 285
           RR+ S   ER R +  RR     R+R RD    RR RS              RS+SP   
Sbjct: 390 RRAKSRSLERKRREPERRRLSSPRTRPRDDILSRRERSKDASPINRWSPTRRRSRSPIRR 449

Query: 286 RSHRHRSHSKSPERSKKSHKKSRRG 310
           RS      S+SP R  +S ++  RG
Sbjct: 450 RSRSPLRRSRSPRRRSRSPRRRDRG 474



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 40/85 (47%), Positives = 48/85 (56%), Gaps = 6/85 (7%)

Query: 189 DDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYR--RSRSRSPRRRSRSP 246
           DD+ S  E  ++   + R  SP  RRRS   + +  RSP  R R  R RSRSPRRR R  
Sbjct: 418 DDILSRRERSKDASPINRW-SPT-RRRSRSPIRRRSRSPLRRSRSPRRRSRSPRRRDRG- 474

Query: 247 KRRSPSPRRERHRSKSPRRHRSRSR 271
            RRS S  R R RS+  RR RSRS+
Sbjct: 475 -RRSRSRLRRRSRSRGGRRRRSRSK 498



 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 39/118 (33%), Positives = 56/118 (47%), Gaps = 14/118 (11%)

Query: 192 ESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSP 251
           E   +  E D++ + + SP     S     K  RSP+ R      RSP+RRS SPK    
Sbjct: 311 ERKSKRSETDKEKKPIKSPSKDASS----GKENRSPSRR----PGRSPKRRSLSPK---- 358

Query: 252 SPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHS-KSPERSKKSHKKSR 308
            PR +  RS+SP  +  RS+  +  SR+ SPG     R      + PER + S  ++R
Sbjct: 359 -PRDKSRRSRSPLLNDRRSKQSKSPSRTLSPGRRAKSRSLERKRREPERRRLSSPRTR 415



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 34/117 (29%), Positives = 53/117 (45%), Gaps = 5/117 (4%)

Query: 192 ESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSP 251
           E +   + ++ K  + PS   +R   +D  +  +SPTLR R        R     K +  
Sbjct: 210 EKTTRSKSKERKKSKSPS---KRSKSQDQARKSKSPTLRRRSQEKIGKARSPTDDKVKIE 266

Query: 252 SPRRERHRSKSPRRHRSRSRDRRHRSRSKSP--GHHRSHRHRSHSKSPERSKKSHKK 306
              + + R KSP  + SRSRDR  +SRS     G  +  R RS  +  +RS+   +K
Sbjct: 267 DKSKSKDRKKSPIINESRSRDRGKKSRSPVDLRGKSKDRRSRSKERKSKRSETDKEK 323



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 29/117 (24%), Positives = 52/117 (44%)

Query: 192 ESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSP 251
           +S  +  +  ++  +  SP  RRRS   + K R     + +       + R +SP     
Sbjct: 224 KSPSKRSKSQDQARKSKSPTLRRRSQEKIGKARSPTDDKVKIEDKSKSKDRKKSPIINES 283

Query: 252 SPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSR 308
             R    +S+SP   R +S+DRR RS+ +      + + +   KSP +   S K++R
Sbjct: 284 RSRDRGKKSRSPVDLRGKSKDRRSRSKERKSKRSETDKEKKPIKSPSKDASSGKENR 340



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 34/107 (31%), Positives = 54/107 (50%), Gaps = 7/107 (6%)

Query: 198 EEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRER 257
           E++ +  +R  SP       RD  K  RSP     R +S+  R RS+  K +     +E+
Sbjct: 266 EDKSKSKDRKKSPIINESRSRDRGKKSRSPV--DLRGKSKDRRSRSKERKSKRSETDKEK 323

Query: 258 HRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSP-ERSKKS 303
              KSP +  S  ++  +RS S+ PG  RS + RS S  P ++S++S
Sbjct: 324 KPIKSPSKDASSGKE--NRSPSRRPG--RSPKRRSLSPKPRDKSRRS 366



 Score = 37.4 bits (85), Expect = 0.017
 Identities = 46/157 (29%), Positives = 73/157 (46%), Gaps = 21/157 (13%)

Query: 161 ILPRLQKRYVLEEAEQ----LEPRV-SALEEDMDDVES-SEEEEEEDEKLERVPSPDHRR 214
           +L  L+K+  L +AE     +E +V S +   +   ES SEEE E  EK         R 
Sbjct: 105 LLEDLEKQRALIKAELDNELMEGKVQSGMGLILQGYESGSEEEGEIHEKARNGNRSSTRS 164

Query: 215 RSYRDLDKPRRSPTLRYRRSRSRSPRR-RSRSPKRRSPSP----RRERHRSKSPRRHRSR 269
            S +   +   +     +RS+SRS  R R RS K++S       + +  RSKS  R +S+
Sbjct: 165 SSTKGKLELVDNKITTKKRSKSRSKERTRHRSDKKKSKGGIEIVKEKTTRSKSKERKKSK 224

Query: 270 SRDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKK 306
           S  +R +S+ ++            SKSP   ++S +K
Sbjct: 225 SPSKRSKSQDQA----------RKSKSPTLRRRSQEK 251



 Score = 33.5 bits (75), Expect = 0.25
 Identities = 18/76 (23%), Positives = 33/76 (43%), Gaps = 5/76 (6%)

Query: 233 RSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRS 292
           +S    P     + ++       E    +S  +H SR + ++H+ RSK    H+ H+H S
Sbjct: 7   QSLREQPEMEDANSEKSINEENGEVSEDQSQNKH-SRHKKKKHKHRSK----HKKHKHSS 61

Query: 293 HSKSPERSKKSHKKSR 308
                ++ K  HK  +
Sbjct: 62  EEDKDKKHKHKHKHKK 77



 Score = 32.7 bits (73), Expect = 0.42
 Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 4/70 (5%)

Query: 247 KRRSPSPRRERHRSKSPRRHRSRS----RDRRHRSRSKSPGHHRSHRHRSHSKSPERSKK 302
           K+RS S  +ER R +S ++         +++  RS+SK     +S   RS S+   R  K
Sbjct: 181 KKRSKSRSKERTRHRSDKKKSKGGIEIVKEKTTRSKSKERKKSKSPSKRSKSQDQARKSK 240

Query: 303 SHKKSRRGNE 312
           S    RR  E
Sbjct: 241 SPTLRRRSQE 250



 Score = 32.3 bits (72), Expect = 0.55
 Identities = 12/49 (24%), Positives = 24/49 (48%), Gaps = 3/49 (6%)

Query: 250 SPSPRRERHRSKSPRRHRSRSRDRRHRSRS---KSPGHHRSHRHRSHSK 295
           S    + +H     ++H+ RS+ ++H+  S   K   H   H+H+ H +
Sbjct: 32  SEDQSQNKHSRHKKKKHKHRSKHKKHKHSSEEDKDKKHKHKHKHKKHKR 80



 Score = 28.5 bits (62), Expect = 8.0
 Identities = 23/77 (29%), Positives = 36/77 (46%), Gaps = 2/77 (2%)

Query: 233 RSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRS 292
           R+ +RS  R S +  +      +   + +S  R + R+R R  + +SK  G        +
Sbjct: 155 RNGNRSSTRSSSTKGKLELVDNKITTKKRSKSRSKERTRHRSDKKKSKG-GIEIVKEKTT 213

Query: 293 HSKSPERSKKSHKKSRR 309
            SKS ER KKS   S+R
Sbjct: 214 RSKSKER-KKSKSPSKR 229


>gi|8922297 LUC7-like isoform a [Homo sapiens]
          Length = 325

 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 55/179 (30%), Positives = 79/179 (44%), Gaps = 23/179 (12%)

Query: 126 DYRKIKSQNRNGEFEL---MHVDEFIDELLHSERVCDIILPRL-----QKRYVLEEAEQL 177
           +  K++++ +  E E    M    F  + L   RVC++    L      +R       +L
Sbjct: 158 EVEKVRAKKKEAEEEYRNSMPASSFQQQKL---RVCEVCSAYLGLHDNDRRLADHFGGKL 214

Query: 178 EPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSR 237
                 + E +D +  +  E++E    +R+   + R R  R L +   S T   RRSRSR
Sbjct: 215 HLGFIQIREKLDQLRKTVAEKQEKRNQDRLRRREEREREER-LSRRSGSRTRDRRRSRSR 273

Query: 238 SPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKS 296
             RRR      RS S  RER +       RSRSRDR  R RS+S  H R HR  S  +S
Sbjct: 274 DRRRR------RSRSTSRERRKLS-----RSRSRDRHRRHRSRSRSHSRGHRRASRDRS 321



 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 38/99 (38%), Positives = 49/99 (49%), Gaps = 1/99 (1%)

Query: 211 DHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRS 270
           D  R++  +  + R    LR R  R R  R   RS  R +   RR R R +  RR RS S
Sbjct: 226 DQLRKTVAEKQEKRNQDRLRRREEREREERLSRRSGSR-TRDRRRSRSRDRRRRRSRSTS 284

Query: 271 RDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSRR 309
           R+RR  SRS+S   HR HR RS S S    + S  +S +
Sbjct: 285 RERRKLSRSRSRDRHRRHRSRSRSHSRGHRRASRDRSAK 323


>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
          Length = 1984

 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 51/119 (42%), Positives = 61/119 (51%), Gaps = 16/119 (13%)

Query: 202  EKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRS----RSRSPRRRS-RSPKRRSP-SPRR 255
            ++  R PS   +RR +   ++  RSP+ R  RS    R RSP +RS R P  RS  SP  
Sbjct: 1635 QRSHRGPS---QRRHHSPSERSHRSPSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSE 1691

Query: 256  ERHRSKSPRRHRSRSRDRRHRSRSK----SPGH--HRSHRHRSHSKSPERSKKSHKKSR 308
             RHRS S R HR  S +RRH S SK    SP    HRS   RSH    ERS  S  + R
Sbjct: 1692 RRHRSPSQRSHRGPS-ERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERR 1749



 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 46/128 (35%), Positives = 55/128 (42%), Gaps = 17/128 (13%)

Query: 194  SEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSP-KRRSPS 252
            S  E       ER       RR +   ++   SP+    RS      RR RSP +RR  S
Sbjct: 1728 SPSERSHHSPSERSHHSPSERRHHSPSERSHCSPS---ERSHCSPSERRHRSPSERRHHS 1784

Query: 253  PRRERHRSKSPRRHRSRSRDRRH----RSR-------SKSPGHHRSHR--HRSHSKSPER 299
            P  + H S S R H S S  RRH    RSR        +SP   RSHR   RSH +  ER
Sbjct: 1785 PSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISER 1844

Query: 300  SKKSHKKS 307
            S    +KS
Sbjct: 1845 SHSPSEKS 1852



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 46/122 (37%), Positives = 50/122 (40%), Gaps = 12/122 (9%)

Query: 193  SSEEEEEEDEKLERVPSP-DHRRRSYRDLDKP----RRSPTLRYRRSRSRSPRRRSRSPK 247
            S        E+  R PS   HR  S R    P     RSP+ R  R  S    RR  SP 
Sbjct: 1658 SERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSE---RRHHSPS 1714

Query: 248  RRS-PSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKK 306
            +RS  SP R  HRS S R H S S    H   S S   H S   RSH    ERS  S  +
Sbjct: 1715 KRSHRSPARRSHRSPSERSHHSPSERSHH---SPSERRHHSPSERSHCSPSERSHCSPSE 1771

Query: 307  SR 308
             R
Sbjct: 1772 RR 1773



 Score = 51.6 bits (122), Expect = 9e-07
 Identities = 46/121 (38%), Positives = 53/121 (43%), Gaps = 18/121 (14%)

Query: 202  EKLERVPSP-DHR----RRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRS-PSPRR 255
            E+  R PS   HR    RR +    +  RSP  R  RS S    R   SP  RS  SP  
Sbjct: 1691 ERRHRSPSQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSE---RSHHSPSERSHHSPSE 1747

Query: 256  ERHRSKSPRRHRSRSR-------DRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSR 308
             RH S S R H S S        +RRHRS S+    H S   +SH    ERS  S  + R
Sbjct: 1748 RRHHSPSERSHCSPSERSHCSPSERRHRSPSER--RHHSPSEKSHHSPSERSHHSPSERR 1805

Query: 309  R 309
            R
Sbjct: 1806 R 1806



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 54/143 (37%), Positives = 65/143 (45%), Gaps = 27/143 (18%)

Query: 193  SSEEEEEEDEKLERVPSP-DHR---RRSYRD-LDKPRRSPTLRYRRS----RSRSPRRRS 243
            S        E+    PS   HR   RRS+R   ++   SP+ R   S    R  SP  RS
Sbjct: 1698 SQRSHRGPSERRHHSPSKRSHRSPARRSHRSPSERSHHSPSERSHHSPSERRHHSPSERS 1757

Query: 244  R-SPKRRSP-SPRRERHRSKSPRRHRSRSRDRRHRSRSK----SPGHHRSH------RH- 290
              SP  RS  SP   RHRS S RRH S S ++ H S S+    SP   R H      RH 
Sbjct: 1758 HCSPSERSHCSPSERRHRSPSERRHHSPS-EKSHHSPSERSHHSPSERRRHSPLERSRHS 1816

Query: 291  ---RSH-SKSPERSKKSHKKSRR 309
               RSH S S  RS +S ++S R
Sbjct: 1817 LLERSHRSPSERRSHRSFERSHR 1839



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 38/90 (42%), Positives = 45/90 (50%), Gaps = 5/90 (5%)

Query: 223  PRRS-PTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKS 281
            P RS  +L  R   S S R      +RR  SP    HRS S R HRS S +RRHRS S+ 
Sbjct: 1618 PERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERSHRSPSERSHRS-SSERRHRSPSQR 1676

Query: 282  PGHHRSHRHRSH-SKSPERSKKSHKKSRRG 310
               HR    RSH S S  R +   ++S RG
Sbjct: 1677 --SHRGPSERSHCSPSERRHRSPSQRSHRG 1704



 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 50/131 (38%), Positives = 58/131 (44%), Gaps = 32/131 (24%)

Query: 206  RVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSR----SPRRRS-RSPKRR---SP------ 251
            R PS   +R S   L++   SP+ R   S SR    SP  RS RSP +R   SP      
Sbjct: 1567 RSPSERSQRSS---LERRHHSPSQRSHCSPSRKNHSSPSERSWRSPSQRNHCSPPERSCH 1623

Query: 252  --------SPRRERHRSKSPRRHRSRSRDRRHRS------RSKSPGHHRSHRHRSHSKSP 297
                    SP +  HR  S RRH S S +R HRS      RS S   HRS   RSH    
Sbjct: 1624 SLSERGLHSPSQRSHRGPSQRRHHSPS-ERSHRSPSERSHRSSSERRHRSPSQRSHRGPS 1682

Query: 298  ERSKKSHKKSR 308
            ERS  S  + R
Sbjct: 1683 ERSHCSPSERR 1693



 Score = 48.5 bits (114), Expect = 7e-06
 Identities = 46/133 (34%), Positives = 57/133 (42%), Gaps = 19/133 (14%)

Query: 193  SSEEEEEEDEKLERVPSPDHR----RRSYRDL-DKPRRSPTLRYRRSRSRSPRRRSRSPK 247
            S +      E+  R PS  +      RS   L ++   SP+ R  R  S+          
Sbjct: 1594 SRKNHSSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQRRHHSPSERS 1653

Query: 248  RRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSK------SPGHHRSHRHRSHSKSPER-- 299
             RSPS R   HRS S RRHRS S+ R HR  S+      S   HRS   RSH    ER  
Sbjct: 1654 HRSPSER--SHRSSSERRHRSPSQ-RSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRH 1710

Query: 300  ---SKKSHKKSRR 309
               SK+SH+   R
Sbjct: 1711 HSPSKRSHRSPAR 1723



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 43/122 (35%), Positives = 53/122 (43%), Gaps = 9/122 (7%)

Query: 194  SEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRS--RSPRRRSRSPKR--- 248
            S  E+      ER       RR +  L++ R S   R  RS S  RS R   RS +R   
Sbjct: 1784 SPSEKSHHSPSERSHHSPSERRRHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISE 1843

Query: 249  RSPSPRRERHRSKSPRRHRSRSRDRRHRSRSK---SPGHHRSHRHRSHSKSPERSKKSHK 305
            RS SP  + H S   R   S S  R H S  K   SP   RSHR  S  +    S++SH+
Sbjct: 1844 RSHSPSEKSHLSPLERSRCSPSERRGHSSSGKTCHSPSE-RSHRSPSGMRQGRTSERSHR 1902

Query: 306  KS 307
             S
Sbjct: 1903 SS 1904



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 40/134 (29%), Positives = 52/134 (38%), Gaps = 8/134 (5%)

Query: 180  RVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSR-SRS 238
            R S LE     +         + +  R     HRR S R      +S      RSR S S
Sbjct: 1806 RHSPLERSRHSLLERSHRSPSERRSHRSFERSHRRISERSHSPSEKSHLSPLERSRCSPS 1865

Query: 239  PRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRH------RS 292
             RR   S  +   SP    HRS S  R + R+ +R HRS  +   H  S         R+
Sbjct: 1866 ERRGHSSSGKTCHSPSERSHRSPSGMR-QGRTSERSHRSSCERTRHSPSEMRPGRPSGRN 1924

Query: 293  HSKSPERSKKSHKK 306
            H    ERS++S  K
Sbjct: 1925 HCSPSERSRRSPLK 1938



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 35/87 (40%), Positives = 40/87 (45%), Gaps = 6/87 (6%)

Query: 225  RSPTLRYRRSRSRSPRRRSRSPKRRSP-SPRRERHRSKSPRRHRSRSRDRRHRSRSKSPG 283
            R+P     R+R     R  RSP  RS  S    RH S S R H S SR + H S S+   
Sbjct: 1548 RTPRGPSERTRHNPSWRNHRSPSERSQRSSLERRHHSPSQRSHCSPSR-KNHSSPSER-- 1604

Query: 284  HHRSHRHRSHSKSPERSKKSHKKSRRG 310
              RS   R+H   PERS   H  S RG
Sbjct: 1605 SWRSPSQRNHCSPPERS--CHSLSERG 1629



 Score = 34.3 bits (77), Expect = 0.15
 Identities = 28/68 (41%), Positives = 34/68 (50%), Gaps = 11/68 (16%)

Query: 242  RSRSPKRRSPSPRR------ERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSK 295
            R R+P  R PS R         HRS S R  RS S +RRH S S+    H S   ++HS 
Sbjct: 1546 RERTP--RGPSERTRHNPSWRNHRSPSERSQRS-SLERRHHSPSQR--SHCSPSRKNHSS 1600

Query: 296  SPERSKKS 303
              ERS +S
Sbjct: 1601 PSERSWRS 1608



 Score = 32.7 bits (73), Expect = 0.42
 Identities = 32/97 (32%), Positives = 37/97 (38%), Gaps = 19/97 (19%)

Query: 212  HRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSR 271
            HR    +   K    P+  YR    R P  R+R       +P    HRS S R  RS S 
Sbjct: 1527 HRHLKDKLTHKEHNHPSF-YRERTPRGPSERTRH------NPSWRNHRSPSERSQRS-SL 1578

Query: 272  DRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSR 308
            +RRH S S           RSH  SP R   S    R
Sbjct: 1579 ERRHHSPS----------QRSHC-SPSRKNHSSPSER 1604


>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
           [Homo sapiens]
          Length = 624

 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 42/133 (31%), Positives = 65/133 (48%), Gaps = 8/133 (6%)

Query: 172 EEAEQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRY 231
           +E ++   R    E+D D  +  E+++E++ + +R    D +R+     DK  R+P   Y
Sbjct: 429 KEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKK----DKKSRTPPRSY 484

Query: 232 ---RRSRSRSPRRRSRSPKRRSPSPRRERH-RSKSPRRHRSRSRDRRHRSRSKSPGHHRS 287
              RRSRS S  RR R  +  S SPR  +  + KS R    RSR+++ + R K   H   
Sbjct: 485 NASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISE 544

Query: 288 HRHRSHSKSPERS 300
            R R  S S  +S
Sbjct: 545 RRERERSTSMRKS 557



 Score = 58.5 bits (140), Expect = 7e-09
 Identities = 45/152 (29%), Positives = 69/152 (45%), Gaps = 7/152 (4%)

Query: 163 PRLQKRYVLEEAEQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDK 222
           P +  +   +E E++  RV   +  +      E  +  + K  R  S  H R   R   K
Sbjct: 264 PEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGR--SRSHTRSKSRSSSK 321

Query: 223 P--RRSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSR--SRDRRHRSR 278
              RR  +    RSRS +  R  +  +RRS SP ++R +S+  R+ RSR  SRD+R  +R
Sbjct: 322 SHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTR 381

Query: 279 SKSPGHHRSHRHRSHSKSPERSKKSHKKSRRG 310
            K     R  + +   K  ER K+  K+  RG
Sbjct: 382 EKIKEKERV-KEKDREKEREREKEREKEKERG 412



 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 37/95 (38%), Positives = 51/95 (53%), Gaps = 8/95 (8%)

Query: 225 RSPTLRYRRSRSRSPRRRSRSPKR-------RSPSPRRERHRSKSPRRHRSRSRDRRHRS 277
           RS T    RS S+S  RR RS  +       RS S +++R RSKSP + RS+SR+RR +S
Sbjct: 309 RSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERR-KS 367

Query: 278 RSKSPGHHRSHRHRSHSKSPERSKKSHKKSRRGNE 312
           RS+S    +    R   K  ER K+  ++  R  E
Sbjct: 368 RSRSHSRDKRKDTREKIKEKERVKEKDREKERERE 402



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 42/134 (31%), Positives = 64/134 (47%), Gaps = 23/134 (17%)

Query: 185 EEDMDDVESSEEEEEEDEKLERVP------------SPDHRRRSYRDLDK-PRRSPTLRY 231
           E + D  +  +E+ ++D+K    P            S + RRR  R   + PR S T++ 
Sbjct: 458 EREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKR 517

Query: 232 RRSRSRSPRRRSRSPKRRSP-----SPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHR 286
           + SRS SPR R++  K+R       S RRER RS S R+  S  RD + +    S     
Sbjct: 518 KSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRK-SSNDRDGKEKLEKNS----T 572

Query: 287 SHRHRSHSKSPERS 300
           S + + H+K P+ S
Sbjct: 573 SLKEKEHNKEPDSS 586



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 35/126 (27%), Positives = 59/126 (46%), Gaps = 5/126 (3%)

Query: 185 EEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSR 244
           E+D +     E E+E ++  ++    +  +   R+ D+ +     R +  +SR+P R   
Sbjct: 426 EKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYN 485

Query: 245 SPKR-RSPSPRRERHRSKSPRRH-RSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSKK 302
           + +R RS S  R R RS+S  R  R+    +R  SRS SP   RS   +   +  ER   
Sbjct: 486 ASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSP---RSRNKKDKKREKERDHI 542

Query: 303 SHKKSR 308
           S ++ R
Sbjct: 543 SERRER 548



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 35/141 (24%), Positives = 65/141 (46%), Gaps = 5/141 (3%)

Query: 173 EAEQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYR 232
           E E+ + +     +D D     + E+++++  ER    +H +   ++ +K +     R +
Sbjct: 402 EKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREK 461

Query: 233 -RSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHR 291
            RS+    +R+     R  P       RS+S  R R R   RR RS S+SP   ++ + +
Sbjct: 462 DRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRR---RRSRSSSRSPRTSKTIKRK 518

Query: 292 SHSKSPERSKKSHKKSRRGNE 312
           S S+SP    ++ K  +R  E
Sbjct: 519 S-SRSPSPRSRNKKDKKREKE 538



 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 34/124 (27%), Positives = 56/124 (45%), Gaps = 6/124 (4%)

Query: 193 SSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRR-RSRSPKRRSP 251
           SS+          +  S  H R   R  D+ RRS +   +RS+SR  R+ RSRS  R   
Sbjct: 319 SSKSHSRRKRSQSKHRSRSHNRSRSRQKDR-RRSKSPHKKRSKSRERRKSRSRSHSRDKR 377

Query: 252 SPRRERHRSKSPRRHRSRSRDR---RHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSR 308
              RE+ + K   + + R ++R   + R + K  G ++  R +   K  E+ K+  ++  
Sbjct: 378 KDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKD-RDKEREKDREKDKEKDRERE 436

Query: 309 RGNE 312
           R  E
Sbjct: 437 REKE 440



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 27/124 (21%), Positives = 47/124 (37%), Gaps = 4/124 (3%)

Query: 193 SSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPS 252
           S        +   R  SP  +R   R+  K R     R +R  +R   +     K +   
Sbjct: 337 SHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDRE 396

Query: 253 PRRERHRSKSPRRHRSRSRDR---RHRSRSKSPGHHRS-HRHRSHSKSPERSKKSHKKSR 308
             RER + +   + R +++DR   R + R K     R   R + H K  ++ K+  +   
Sbjct: 397 KEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKE 456

Query: 309 RGNE 312
           +  E
Sbjct: 457 KERE 460



 Score = 37.4 bits (85), Expect = 0.017
 Identities = 27/134 (20%), Positives = 53/134 (39%), Gaps = 24/134 (17%)

Query: 175 EQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRS 234
           E+++ +    E+D +     E+E E++++  +    D  R   R+ DK            
Sbjct: 382 EKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDK-----------E 430

Query: 235 RSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHS 294
           + R   R     K R     +E+ + K   + RS+  D + +   KS             
Sbjct: 431 KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKS------------- 477

Query: 295 KSPERSKKSHKKSR 308
           ++P RS  + ++SR
Sbjct: 478 RTPPRSYNASRRSR 491


>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
           [Homo sapiens]
          Length = 508

 Score = 62.0 bits (149), Expect = 7e-10
 Identities = 42/133 (31%), Positives = 65/133 (48%), Gaps = 8/133 (6%)

Query: 172 EEAEQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRY 231
           +E ++   R    E+D D  +  E+++E++ + +R    D +R+     DK  R+P   Y
Sbjct: 313 KEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKK----DKKSRTPPRSY 368

Query: 232 ---RRSRSRSPRRRSRSPKRRSPSPRRERH-RSKSPRRHRSRSRDRRHRSRSKSPGHHRS 287
              RRSRS S  RR R  +  S SPR  +  + KS R    RSR+++ + R K   H   
Sbjct: 369 NASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISE 428

Query: 288 HRHRSHSKSPERS 300
            R R  S S  +S
Sbjct: 429 RRERERSTSMRKS 441



 Score = 58.5 bits (140), Expect = 7e-09
 Identities = 45/152 (29%), Positives = 69/152 (45%), Gaps = 7/152 (4%)

Query: 163 PRLQKRYVLEEAEQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDK 222
           P +  +   +E E++  RV   +  +      E  +  + K  R  S  H R   R   K
Sbjct: 148 PEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGR--SRSHTRSKSRSSSK 205

Query: 223 P--RRSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSR--SRDRRHRSR 278
              RR  +    RSRS +  R  +  +RRS SP ++R +S+  R+ RSR  SRD+R  +R
Sbjct: 206 SHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTR 265

Query: 279 SKSPGHHRSHRHRSHSKSPERSKKSHKKSRRG 310
            K     R  + +   K  ER K+  K+  RG
Sbjct: 266 EKIKEKERV-KEKDREKEREREKEREKEKERG 296



 Score = 55.5 bits (132), Expect = 6e-08
 Identities = 37/95 (38%), Positives = 51/95 (53%), Gaps = 8/95 (8%)

Query: 225 RSPTLRYRRSRSRSPRRRSRSPKR-------RSPSPRRERHRSKSPRRHRSRSRDRRHRS 277
           RS T    RS S+S  RR RS  +       RS S +++R RSKSP + RS+SR+RR +S
Sbjct: 193 RSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERR-KS 251

Query: 278 RSKSPGHHRSHRHRSHSKSPERSKKSHKKSRRGNE 312
           RS+S    +    R   K  ER K+  ++  R  E
Sbjct: 252 RSRSHSRDKRKDTREKIKEKERVKEKDREKERERE 286



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 42/134 (31%), Positives = 64/134 (47%), Gaps = 23/134 (17%)

Query: 185 EEDMDDVESSEEEEEEDEKLERVP------------SPDHRRRSYRDLDK-PRRSPTLRY 231
           E + D  +  +E+ ++D+K    P            S + RRR  R   + PR S T++ 
Sbjct: 342 EREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKR 401

Query: 232 RRSRSRSPRRRSRSPKRRSP-----SPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHR 286
           + SRS SPR R++  K+R       S RRER RS S R+  S  RD + +    S     
Sbjct: 402 KSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRK-SSNDRDGKEKLEKNS----T 456

Query: 287 SHRHRSHSKSPERS 300
           S + + H+K P+ S
Sbjct: 457 SLKEKEHNKEPDSS 470



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 35/126 (27%), Positives = 59/126 (46%), Gaps = 5/126 (3%)

Query: 185 EEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSR 244
           E+D +     E E+E ++  ++    +  +   R+ D+ +     R +  +SR+P R   
Sbjct: 310 EKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYN 369

Query: 245 SPKR-RSPSPRRERHRSKSPRRH-RSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSKK 302
           + +R RS S  R R RS+S  R  R+    +R  SRS SP   RS   +   +  ER   
Sbjct: 370 ASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSP---RSRNKKDKKREKERDHI 426

Query: 303 SHKKSR 308
           S ++ R
Sbjct: 427 SERRER 432



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 35/141 (24%), Positives = 65/141 (46%), Gaps = 5/141 (3%)

Query: 173 EAEQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYR 232
           E E+ + +     +D D     + E+++++  ER    +H +   ++ +K +     R +
Sbjct: 286 EKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREK 345

Query: 233 -RSRSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHR 291
            RS+    +R+     R  P       RS+S  R R R   RR RS S+SP   ++ + +
Sbjct: 346 DRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRR---RRSRSSSRSPRTSKTIKRK 402

Query: 292 SHSKSPERSKKSHKKSRRGNE 312
           S S+SP    ++ K  +R  E
Sbjct: 403 S-SRSPSPRSRNKKDKKREKE 422



 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 34/124 (27%), Positives = 56/124 (45%), Gaps = 6/124 (4%)

Query: 193 SSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRR-RSRSPKRRSP 251
           SS+          +  S  H R   R  D+ RRS +   +RS+SR  R+ RSRS  R   
Sbjct: 203 SSKSHSRRKRSQSKHRSRSHNRSRSRQKDR-RRSKSPHKKRSKSRERRKSRSRSHSRDKR 261

Query: 252 SPRRERHRSKSPRRHRSRSRDR---RHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSR 308
              RE+ + K   + + R ++R   + R + K  G ++  R +   K  E+ K+  ++  
Sbjct: 262 KDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKD-RDKEREKDREKDKEKDRERE 320

Query: 309 RGNE 312
           R  E
Sbjct: 321 REKE 324



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 27/124 (21%), Positives = 47/124 (37%), Gaps = 4/124 (3%)

Query: 193 SSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPS 252
           S        +   R  SP  +R   R+  K R     R +R  +R   +     K +   
Sbjct: 221 SHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDRE 280

Query: 253 PRRERHRSKSPRRHRSRSRDR---RHRSRSKSPGHHRS-HRHRSHSKSPERSKKSHKKSR 308
             RER + +   + R +++DR   R + R K     R   R + H K  ++ K+  +   
Sbjct: 281 KEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKE 340

Query: 309 RGNE 312
           +  E
Sbjct: 341 KERE 344



 Score = 37.4 bits (85), Expect = 0.017
 Identities = 27/134 (20%), Positives = 53/134 (39%), Gaps = 24/134 (17%)

Query: 175 EQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRS 234
           E+++ +    E+D +     E+E E++++  +    D  R   R+ DK            
Sbjct: 266 EKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDK-----------E 314

Query: 235 RSRSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHS 294
           + R   R     K R     +E+ + K   + RS+  D + +   KS             
Sbjct: 315 KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKS------------- 361

Query: 295 KSPERSKKSHKKSR 308
           ++P RS  + ++SR
Sbjct: 362 RTPPRSYNASRRSR 375


>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
           sapiens]
          Length = 820

 Score = 61.6 bits (148), Expect = 9e-10
 Identities = 39/92 (42%), Positives = 51/92 (55%), Gaps = 5/92 (5%)

Query: 222 KPRRSPTLRYRRSRSRSP-RRRSRSPKRRS-PSPRRERHRSKSPRRHRSRSRDRRHRSRS 279
           K R +   +  R RSR+P R R R   R+S PS  R+RHRS+  RR  SRSR    RSRS
Sbjct: 9   KDRDASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRS---RSRS 65

Query: 280 KSPGHHRSHRHRSHSKSPERSKKSHKKSRRGN 311
           KS    R H+ R   K  +R+KK   + + G+
Sbjct: 66  KSAERERRHKERERDKERDRNKKDRDRDKDGH 97



 Score = 55.1 bits (131), Expect = 8e-08
 Identities = 44/114 (38%), Positives = 59/114 (51%), Gaps = 12/114 (10%)

Query: 208 PSPDHRRRSY-----RDLDKPRRS-PTLRYRRSRSRSPRR---RSRSPKRRSPSPRRERH 258
           PS + R+RS      RD D+ R+S P+   +R RSR  RR   RSRS + RS S  RER 
Sbjct: 15  PSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRS-RSRSKSAERER- 72

Query: 259 RSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSRRGNE 312
           R K   R + R R+++ R R K  GH R    +  S SP R K    +  R ++
Sbjct: 73  RHKERERDKERDRNKKDRDRDKD-GHRRDKDRKRSSLSPGRGKDFKSRKDRDSK 125



 Score = 48.9 bits (115), Expect = 6e-06
 Identities = 38/132 (28%), Positives = 55/132 (41%), Gaps = 9/132 (6%)

Query: 185 EEDMDDVESSEE-------EEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYR-RSRS 236
           ++D D   S EE       + E D   +R  SP   R+ +R  D+ R     R R RS+S
Sbjct: 8   KKDRDASPSKEERKRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKS 67

Query: 237 RSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKS 296
               RR +  +R     R ++ R +    HR R +DR+  S S   G     R    SK 
Sbjct: 68  AERERRHKERERDKERDRNKKDRDRDKDGHR-RDKDRKRSSLSPGRGKDFKSRKDRDSKK 126

Query: 297 PERSKKSHKKSR 308
            E  +   KK +
Sbjct: 127 DEEDEHGDKKPK 138



 Score = 29.6 bits (65), Expect = 3.6
 Identities = 25/131 (19%), Positives = 47/131 (35%), Gaps = 11/131 (8%)

Query: 190 DVESSEEEEEEDEKLERVP-----------SPDHRRRSYRDLDKPRRSPTLRYRRSRSRS 238
           D +  EE+E  D+K +  P           + +      + L K  R      RR +   
Sbjct: 123 DSKKDEEDEHGDKKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVE 182

Query: 239 PRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPE 298
            R+R    +R+     ++  R           R+RR R   ++ G+      +   +  +
Sbjct: 183 ERQRMLEEERKKRKQFQDLGRKMLEDPQERERRERRERMERETNGNEDEEGRQKIREEKD 242

Query: 299 RSKKSHKKSRR 309
           +SK+ H    R
Sbjct: 243 KSKELHAIKER 253


>gi|4757926 RNA binding motif protein 39 isoform b [Homo sapiens]
          Length = 524

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 43/131 (32%), Positives = 62/131 (47%), Gaps = 17/131 (12%)

Query: 190 DVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRR 249
           D+E+  E   + ++ +   +  H  RS +      RS +   +RS+S+  +R     +++
Sbjct: 6   DIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKK 65

Query: 250 SPSPRRERHRSKSPRRHRSRSRDRRHRSRSKS-----------------PGHHRSHRHRS 292
           S S  R+R RSK  RR RSRSRDRR R R +S                 P   +  R RS
Sbjct: 66  SKSRERKRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRS 125

Query: 293 HSKSPERSKKS 303
            SKSP R  KS
Sbjct: 126 RSKSPFRKDKS 136



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 31/93 (33%), Positives = 46/93 (49%), Gaps = 5/93 (5%)

Query: 219 DLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSPR---RERHRSKSPRRHRSRSRDRRH 275
           D++    +P  +     S +     RS KR+    R    ER RSKS  R RSR R+R+ 
Sbjct: 6   DIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERK- 64

Query: 276 RSRSKSPGHHRS-HRHRSHSKSPERSKKSHKKS 307
           +S+S+     RS  R RS S+S +R  +   +S
Sbjct: 65  KSKSRERKRSRSKERRRSRSRSRDRRFRGRYRS 97



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 25/54 (46%), Positives = 31/54 (57%), Gaps = 2/54 (3%)

Query: 258 HRSKSPRRHRSRSRDRRH-RSRSKSPGHHRSH-RHRSHSKSPERSKKSHKKSRR 309
           H  +S +R +S+SR R H R RSKS    RS  R R  SKS ER +   K+ RR
Sbjct: 28  HEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRERKRSRSKERRR 81



 Score = 33.1 bits (74), Expect = 0.33
 Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 4/59 (6%)

Query: 254 RRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSRRGNE 312
           +++ ++  S   H  RS+ R+ +S+S+S  H R    RS SK  +RS+   +K  +  E
Sbjct: 16  KKDENKLSSANGHEERSKKRK-KSKSRSRSHERK---RSKSKERKRSRDRERKKSKSRE 70


>gi|35493811 RNA binding motif protein 39 isoform a [Homo sapiens]
          Length = 530

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 43/131 (32%), Positives = 62/131 (47%), Gaps = 17/131 (12%)

Query: 190 DVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRR 249
           D+E+  E   + ++ +   +  H  RS +      RS +   +RS+S+  +R     +++
Sbjct: 6   DIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKK 65

Query: 250 SPSPRRERHRSKSPRRHRSRSRDRRHRSRSKS-----------------PGHHRSHRHRS 292
           S S  R+R RSK  RR RSRSRDRR R R +S                 P   +  R RS
Sbjct: 66  SKSRERKRSRSKERRRSRSRSRDRRFRGRYRSPYSGPKFNSAIRGKIGLPHSIKLSRRRS 125

Query: 293 HSKSPERSKKS 303
            SKSP R  KS
Sbjct: 126 RSKSPFRKDKS 136



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 31/93 (33%), Positives = 46/93 (49%), Gaps = 5/93 (5%)

Query: 219 DLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSPR---RERHRSKSPRRHRSRSRDRRH 275
           D++    +P  +     S +     RS KR+    R    ER RSKS  R RSR R+R+ 
Sbjct: 6   DIEAMLEAPYKKDENKLSSANGHEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERK- 64

Query: 276 RSRSKSPGHHRS-HRHRSHSKSPERSKKSHKKS 307
           +S+S+     RS  R RS S+S +R  +   +S
Sbjct: 65  KSKSRERKRSRSKERRRSRSRSRDRRFRGRYRS 97



 Score = 42.0 bits (97), Expect = 7e-04
 Identities = 25/54 (46%), Positives = 31/54 (57%), Gaps = 2/54 (3%)

Query: 258 HRSKSPRRHRSRSRDRRH-RSRSKSPGHHRSH-RHRSHSKSPERSKKSHKKSRR 309
           H  +S +R +S+SR R H R RSKS    RS  R R  SKS ER +   K+ RR
Sbjct: 28  HEERSKKRKKSKSRSRSHERKRSKSKERKRSRDRERKKSKSRERKRSRSKERRR 81



 Score = 33.1 bits (74), Expect = 0.33
 Identities = 18/59 (30%), Positives = 32/59 (54%), Gaps = 4/59 (6%)

Query: 254 RRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSRRGNE 312
           +++ ++  S   H  RS+ R+ +S+S+S  H R    RS SK  +RS+   +K  +  E
Sbjct: 16  KKDENKLSSANGHEERSKKRK-KSKSRSRSHERK---RSKSKERKRSRDRERKKSKSRE 70


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 38/147 (25%), Positives = 59/147 (40%), Gaps = 3/147 (2%)

Query: 166 QKRYVLEEAEQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRR 225
           +KR   E  ++ E +    E+   +    E  + + EK +R      RR   +  ++  R
Sbjct: 64  KKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKER 123

Query: 226 SPTLRYRRSRSRSPRR---RSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSP 282
               + RR R R  RR   R +  KR     +RER R K  +  R + R+R  + R K  
Sbjct: 124 ERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKER 183

Query: 283 GHHRSHRHRSHSKSPERSKKSHKKSRR 309
                   +   K   R KK  KK R+
Sbjct: 184 ERKERRERKKERKKERRKKKERKKDRK 210



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 31/136 (22%), Positives = 60/136 (44%), Gaps = 4/136 (2%)

Query: 180 RVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSY---RDLDKPRRSPTLRYRRSRS 236
           R S  +++  + E  + E E++ K ER      +R+     ++ ++ R+    + +  R 
Sbjct: 32  RESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91

Query: 237 RSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKS 296
           +  R+R +  K+R    R  R R K   R + R R+ + R   K     +  R +   + 
Sbjct: 92  KERRKRKKEKKKRERKQRGRRERKKKKER-KERERENKQRRERKRKKRRKKKRRKERKRE 150

Query: 297 PERSKKSHKKSRRGNE 312
            ER K+  K+ +R  E
Sbjct: 151 KERGKRERKRKKRKKE 166



 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 30/121 (24%), Positives = 52/121 (42%), Gaps = 5/121 (4%)

Query: 193 SSEEEEEEDEKLERVPSPDHRRRS-YRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSP 251
           +  E E + E+ ER      R +   R+  K  +    +  R + R  +R+ R  +R+  
Sbjct: 30  TQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER 89

Query: 252 SPRRERHRSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSRRGN 311
             +  R R K  ++   + R RR R + K     R  R R + +  ER +K  +K +R  
Sbjct: 90  REKERRKRKKEKKKRERKQRGRRERKKKK----ERKERERENKQRRERKRKKRRKKKRRK 145

Query: 312 E 312
           E
Sbjct: 146 E 146



 Score = 52.0 bits (123), Expect = 7e-07
 Identities = 38/143 (26%), Positives = 57/143 (39%), Gaps = 8/143 (5%)

Query: 173 EAEQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYR 232
           E E+   R    +E     +    +E E ++ ER      RR   R   K  +    R +
Sbjct: 49  EREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQ 108

Query: 233 RSRSRSPRRRSRSPKRRSPSPRRERHRSKSPR------RHRSRSRDRRHRSRSKSPGHHR 286
           R R    +++ R  + R    RRER R K  +      R R + R +R R R K     R
Sbjct: 109 RGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEER 168

Query: 287 SHRHRSHSKSPERSKKSHKKSRR 309
             +   + K  ER K+  +K RR
Sbjct: 169 EKKRERNRK--ERKKERERKERR 189



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 33/143 (23%), Positives = 59/143 (41%), Gaps = 8/143 (5%)

Query: 172 EEAEQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRY 231
           +E ++ + R    E +    E  ++ +E  EK  R    + ++R  +   +  R      
Sbjct: 61  KEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKER 120

Query: 232 RRSRSRSPRRRSRSPKRRSPSPR-----RERHRSKSPRRHRSRSRDRRHRSRSKSPGHHR 286
           +     + +RR R  K+R    R     RE+ R K  R+ + R ++ R + R ++    +
Sbjct: 121 KERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERK 180

Query: 287 SHRHRSHSKSPERSKKSHKKSRR 309
             R R   K     KK  KK RR
Sbjct: 181 KERER---KERRERKKERKKERR 200



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 25/106 (23%), Positives = 42/106 (39%), Gaps = 3/106 (2%)

Query: 207 VPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPKRRSPSPRRERHRSKSPR-- 264
           +  P  +R S R  ++  R    R R    +  R +    KR+     +ER R +  R  
Sbjct: 25  ISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREK 84

Query: 265 -RHRSRSRDRRHRSRSKSPGHHRSHRHRSHSKSPERSKKSHKKSRR 309
            R   R ++RR R + K     +    R   K  ER ++  +  +R
Sbjct: 85  QRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQR 130



 Score = 36.6 bits (83), Expect = 0.029
 Identities = 29/130 (22%), Positives = 52/130 (40%), Gaps = 13/130 (10%)

Query: 166 QKRYVLEEAEQLEPRVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLD---- 221
           ++R   +E ++ E +     E     E  E E E  ++ ER      +++  ++      
Sbjct: 93  ERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKE 152

Query: 222 --------KPRRSPTLRYRRSRSRSPRRRSRSPK-RRSPSPRRERHRSKSPRRHRSRSRD 272
                   K R+      +R R+R  R++ R  K RR     R++ R K   R + R  D
Sbjct: 153 RGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTD 212

Query: 273 RRHRSRSKSP 282
           R+  S+   P
Sbjct: 213 RQTDSQVFRP 222


>gi|122937227 U2-associated SR140 protein [Homo sapiens]
          Length = 1029

 Score = 60.8 bits (146), Expect = 1e-09
 Identities = 59/215 (27%), Positives = 97/215 (45%), Gaps = 41/215 (19%)

Query: 121  EPLYNDYRKIKSQNRNGEFEL-MHVDEFIDELLHSERVCDIILPRLQKRYVLEEAEQLEP 179
            E  ++ Y ++  + R    E+ + V +F DEL   +R      P+   +   E+ E    
Sbjct: 827  ESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKR------PKKPGQSFQEQVEHYRD 880

Query: 180  RVSALEEDMDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSR---S 236
            ++   E++ +     E ++++ EKLE         RS    +K   +PT + R+ R   S
Sbjct: 881  KLLQREKEKELERERERDKKDKEKLES--------RSKDKKEKDECTPTRKERKRRHSTS 932

Query: 237  RSPRRRSRSPKRRSPSPRRERHRSKSPRRHRSRSRDR---------------RHRSRSKS 281
             SP R S   + +SPSP+ ER   +S R H+  SR R               R  S S++
Sbjct: 933  PSPSRSSSGRRVKSPSPKSERSE-RSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRT 991

Query: 282  PGHHRSHRHRSHSKSPERSK-------KSHKKSRR 309
            P   R  R RS  KS ++S+       +SHKKS++
Sbjct: 992  PKRSRRSRSRSPKKSGKKSRSQSRSPHRSHKKSKK 1026



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 58/221 (26%), Positives = 99/221 (44%), Gaps = 30/221 (13%)

Query: 89   EFIKNEDFKYVRMLGALYMRLTGTAIDCYKYLEPLYNDYRKIKSQNRNGEFELMHVDEFI 148
            E  +++  KY  M      +L    +   K+ + L +  R  K     G+     V+ + 
Sbjct: 824  EMTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRPKKP----GQSFQEQVEHYR 879

Query: 149  DELLHSERVCDIILPRLQKRYVLEEAEQLEPRVSALEEDMDDVESSEEEEEEDEKLERVP 208
            D+LL  E+  ++   R + +   ++ E+LE R S  +++ D+   + +E +        P
Sbjct: 880  DKLLQREKEKELERERERDK---KDKEKLESR-SKDKKEKDECTPTRKERKRRHSTSPSP 935

Query: 209  SPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSR---SPK------RRSPS----PRR 255
            S     R  +    P+   + R  RS   S R RS    SP+      +RSPS    P+R
Sbjct: 936  SRSSSGRRVKS-PSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKR 994

Query: 256  ERH-RSKSPRRHRSRSRDRRHRSRSKSPGHHRSHRHRSHSK 295
             R  RS+SP++   +S     RS+S+SP  HRSH+    +K
Sbjct: 995  SRRSRSRSPKKSGKKS-----RSQSRSP--HRSHKKSKKNK 1028



 Score = 37.4 bits (85), Expect = 0.017
 Identities = 30/86 (34%), Positives = 42/86 (48%), Gaps = 18/86 (20%)

Query: 191  VESSEEEEEEDEKLERVPSPDHRRRSY-----RDLDKP-RRSPT-----LRYRRSRSRSP 239
            V+S   + E  E+ ER      R RS      RD+ K  +RSP+      R RRSRSRSP
Sbjct: 944  VKSPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSP 1003

Query: 240  RR-------RSRSPKRRSPSPRRERH 258
            ++       +SRSP R     ++ +H
Sbjct: 1004 KKSGKKSRSQSRSPHRSHKKSKKNKH 1029



 Score = 32.3 bits (72), Expect = 0.55
 Identities = 41/181 (22%), Positives = 67/181 (37%), Gaps = 56/181 (30%)

Query: 185 EEDMDDVESSEEEEEEDEK-LERVPSPDHRRRS--------------YRDLDKPRRSP-- 227
           EE  ++   ++EEE EDE+  +   S +H   S              Y ++ + +R+   
Sbjct: 786 EESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLR 845

Query: 228 TLRYRRSRSRSPRRRSRSPKRRSPSPRRE--------RHRSKSPRRHRSRSRDRRHR--- 276
            +  +  + +      + PK+   S + +          R K     R R RD++ +   
Sbjct: 846 EIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKL 905

Query: 277 -SRSKSPGHH------RSHRHRSHSKSP---------------------ERSKKSHKKSR 308
            SRSK           R  R R HS SP                     ERS++SHK+S 
Sbjct: 906 ESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESS 965

Query: 309 R 309
           R
Sbjct: 966 R 966



 Score = 30.8 bits (68), Expect = 1.6
 Identities = 26/120 (21%), Positives = 50/120 (41%), Gaps = 13/120 (10%)

Query: 191 VESSEEEEEEDEKLERVPSPDHR---RRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPK 247
           V +++EE E DEK  ++  P  R   +++  +     R P+L    ++ + P ++    K
Sbjct: 141 VNAAKEEHETDEKRGKIYKPSSRFADQKNPPNQSSNERPPSLLVIETK-KPPLKKGEKEK 199

Query: 248 RRSPSPRRERHRSKSPRRHRSRSRDRRHRSRSK----SPGHHRSHRHRSHSKSPERSKKS 303
           ++S          K   +     RD RH+++ +     P    S   R    +P R  +S
Sbjct: 200 KKS-----NLELFKEELKQIQEERDERHKTKGRLSRFEPPQSDSDGQRRSMDAPSRRNRS 254


>gi|23111062 splicing factor, arginine/serine-rich 8 [Homo sapiens]
          Length = 951

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 56/168 (33%), Positives = 80/168 (47%), Gaps = 37/168 (22%)

Query: 180 RVSALEEDMDDVESSEEEEEEDEKLERV--------PSPDHRRRSYRDLDK--PRRSPTL 229
           R S+  +D    E  E+++++ +K  R          S   R RS+       P    T+
Sbjct: 740 RPSSKSKDPPREEEKEKKKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTV 799

Query: 230 RYRRSRSRSPRRRSRSPKRR--------------SPSPRRERHRSKSP----RRHRSRSR 271
           R  RSRSRSPRRR+ SP+RR              SP   R+R RS+SP    ++ RSRSR
Sbjct: 800 RRSRSRSRSPRRRAHSPERRREERSVPTAYRVSRSPGASRKRTRSRSPHEKKKKRRSRSR 859

Query: 272 DR-RHRSRSKSPGHHRSHR------HRSHSK--SPERSKKSHKKSRRG 310
            + + RS+S SP    + R      H +HS   SP  S+ S ++  RG
Sbjct: 860 TKSKARSQSVSPSKQAAPRPAAPAAHSAHSASVSPVESRGSSQERSRG 907



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 48/188 (25%), Positives = 81/188 (43%), Gaps = 9/188 (4%)

Query: 131 KSQNRNGEFELMHVDEFIDELLHS---ERVCDIILPRLQKRYVLEEAEQLEPRVSALEED 187
           K Q    E E     + +++ L +   E++        +K+   E   +    +  L+  
Sbjct: 638 KPQLTQEELEAKQAKQKLEDRLAAAAREKLAQASKESKEKQLQAERKRKAALFLQTLKNP 697

Query: 188 MDDVESSEEEEEEDEKLERVPSPDHRRRSYRDLDKPRRSPTLRYRRSRSRSPRRRSRSPK 247
           + + E+ + EE      E   +P       R L      P  R   S+S+ P R     K
Sbjct: 698 LPEAEAGKIEESPFSVEESSTTPCPLLTGGRPLPTLEVKPPDR-PSSKSKDPPREEEKEK 756

Query: 248 RRSPSPRRERHRSKSPRRHRS-RSRDRRH-RSRSKSPGHHRS-HRHRSHSKSPERSKKSH 304
           ++    +R R RS+SP+ H S +SR R H +++   P  +R+  R RS S+SP R  ++H
Sbjct: 757 KKKKHKKRSRTRSRSPKYHSSSKSRSRSHSKAKHSLPSAYRTVRRSRSRSRSPRR--RAH 814

Query: 305 KKSRRGNE 312
              RR  E
Sbjct: 815 SPERRREE 822


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,348,383
Number of Sequences: 37866
Number of extensions: 707058
Number of successful extensions: 20576
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 434
Number of HSP's successfully gapped in prelim test: 631
Number of HSP's that attempted gapping in prelim test: 8885
Number of HSP's gapped (non-prelim): 5877
length of query: 312
length of database: 18,247,518
effective HSP length: 102
effective length of query: 210
effective length of database: 14,385,186
effective search space: 3020889060
effective search space used: 3020889060
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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