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Search of human proteins with 24432067
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24432067 FRA10AC1 protein [Homo sapiens]
(315 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24432067 FRA10AC1 protein [Homo sapiens] 655 0.0
gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sap... 44 2e-04
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 43 3e-04
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 42 5e-04
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 42 7e-04
gi|169234949 CWF19-like 2, cell cycle control [Homo sapiens] 41 0.001
gi|21389511 zinc finger, matrin type 2 [Homo sapiens] 41 0.001
gi|38788333 remodeling and spacing factor 1 [Homo sapiens] 40 0.003
gi|50962882 G patch domain containing 8 [Homo sapiens] 40 0.003
gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo ... 40 0.004
gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo... 39 0.005
gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo... 39 0.005
gi|195976782 Paf1/RNA polymerase II complex component [Homo sapi... 39 0.008
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 38 0.010
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 38 0.010
gi|192807334 arsenate resistance protein 2 isoform d [Homo sapiens] 38 0.010
gi|58331218 arsenate resistance protein 2 isoform a [Homo sapiens] 38 0.010
gi|4504487 histidine rich calcium binding protein precursor [Hom... 38 0.010
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 38 0.010
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 38 0.010
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 38 0.010
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 38 0.010
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 38 0.010
gi|239756568 PREDICTED: similar to BCL2-associated transcription... 38 0.013
gi|169218320 PREDICTED: similar to BCL2-associated transcription... 38 0.013
gi|11968023 zinc finger protein 106 homolog [Homo sapiens] 38 0.013
gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens] 38 0.013
gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 38 0.013
gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo ... 37 0.017
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 37 0.017
>gi|24432067 FRA10AC1 protein [Homo sapiens]
Length = 315
Score = 655 bits (1690), Expect = 0.0
Identities = 315/315 (100%), Positives = 315/315 (100%)
Query: 1 MHGHGGYDSDFSDDERCGESSKRKKRTVEDDLLLQKPFQKEKHGKVAHKQVAAELLDREE 60
MHGHGGYDSDFSDDERCGESSKRKKRTVEDDLLLQKPFQKEKHGKVAHKQVAAELLDREE
Sbjct: 1 MHGHGGYDSDFSDDERCGESSKRKKRTVEDDLLLQKPFQKEKHGKVAHKQVAAELLDREE 60
Query: 61 ARNRRFHLIAMDAYQRHTKFVNDYILYYGGKKEDFKRLGENDKTDLDVIRENHRFLWNEE 120
ARNRRFHLIAMDAYQRHTKFVNDYILYYGGKKEDFKRLGENDKTDLDVIRENHRFLWNEE
Sbjct: 61 ARNRRFHLIAMDAYQRHTKFVNDYILYYGGKKEDFKRLGENDKTDLDVIRENHRFLWNEE 120
Query: 121 DEMDMTWEKRLAKKYYDKLFKEYCIADLSKYKENKFGFRWRVEKEVISGKGQFFCGNKYC 180
DEMDMTWEKRLAKKYYDKLFKEYCIADLSKYKENKFGFRWRVEKEVISGKGQFFCGNKYC
Sbjct: 121 DEMDMTWEKRLAKKYYDKLFKEYCIADLSKYKENKFGFRWRVEKEVISGKGQFFCGNKYC 180
Query: 181 DKKEGLKSWEVNFGYIEHGEKRNALVKLRLCQECSIKLNFHHRRKEIKSKKRKDKTKKDC 240
DKKEGLKSWEVNFGYIEHGEKRNALVKLRLCQECSIKLNFHHRRKEIKSKKRKDKTKKDC
Sbjct: 181 DKKEGLKSWEVNFGYIEHGEKRNALVKLRLCQECSIKLNFHHRRKEIKSKKRKDKTKKDC 240
Query: 241 EESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEESASESELWKGPLPETDEK 300
EESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEESASESELWKGPLPETDEK
Sbjct: 241 EESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEESASESELWKGPLPETDEK 300
Query: 301 SQEEEFDEYFQDLFL 315
SQEEEFDEYFQDLFL
Sbjct: 301 SQEEEFDEYFQDLFL 315
>gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo
sapiens]
Length = 2211
Score = 43.9 bits (102), Expect = 2e-04
Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 14/89 (15%)
Query: 225 KEIKSKKRKDKTKKDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEESA 284
+E + KK KDK ++ KK RL + + KKK KG + E+ +S EES+
Sbjct: 912 EEARKKKEKDKLRQLL-----KKERLKAKLQRKKKKRKGSDEEDEGEEE--ESSSSEESS 964
Query: 285 SESELWKGPLPETDEKSQEEEFDEYFQDL 313
SE E E +E+ +EEEF Q++
Sbjct: 965 SEEE-------EMEEEEEEEEFGPGMQEV 986
>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 123
Score = 43.1 bits (100), Expect = 3e-04
Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 3/86 (3%)
Query: 223 RRKEIKSKKRKDKTKKDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEE 282
+RKE + +KRK+K KK + + K+ EE KK+ + K+ E+ +EEE
Sbjct: 28 KRKEKRKEKRKEKEKKKKTKETEKR---KEKEEEEKKRKRKRKKKKEEEEREEEEEEEEE 84
Query: 283 SASESELWKGPLPETDEKSQEEEFDE 308
E E +G + +K + +E +E
Sbjct: 85 EKEEEEKEEGRRRKKKKKRRRKEEEE 110
Score = 42.0 bits (97), Expect = 7e-04
Identities = 22/84 (26%), Positives = 42/84 (50%)
Query: 225 KEIKSKKRKDKTKKDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEESA 284
K+ K KK++ + ++ EE+ ++ + +E K+K K KK++++ R EEE
Sbjct: 1 KKKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEK 60
Query: 285 SESELWKGPLPETDEKSQEEEFDE 308
K E + + +EEE +E
Sbjct: 61 KRKRKRKKKKEEEEREEEEEEEEE 84
Score = 38.1 bits (87), Expect = 0.010
Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 11/81 (13%)
Query: 225 KEIKSKKRKDKTKKDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEESA 284
+E K KRK+K K+ +E KK +E K+K+K K+ + +EE
Sbjct: 22 EEEKEGKRKEKRKEKRKEKEKKKK----TKETEKRKEKEEEEKKRKRKRKKKKEEEEREE 77
Query: 285 SESELWKGPLPETDEKSQEEE 305
E E E +EK +EE+
Sbjct: 78 EEEE-------EEEEKEEEEK 91
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 42.4 bits (98), Expect = 5e-04
Identities = 50/232 (21%), Positives = 101/232 (43%), Gaps = 30/232 (12%)
Query: 91 KKEDFKRLGENDKTDLDVIRENHRFLWNEEDEM----DMTWEKRLAKKYYDKLF--KEYC 144
++E + E + + +R +W +E++M +M WEK + +++ KE
Sbjct: 380 QEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 439
Query: 145 IADLSKYKENKFGFRWRVEKEVISGKGQFFCGNKYCDKKEGLKSWEVNFGYIEHGEKRNA 204
I +L + + R + EK K + + +++ K W E EK
Sbjct: 440 IRELEEKMHEQEKIREQEEKRQEEEKIR----EQEKRQEQEAKMWRQEEKIREQEEKIRE 495
Query: 205 LVKLRLCQECSIKLNFHHRRKEIKSKKRKDKTKKDCEESSHKKSRLSSAEEASKKKDKGH 264
+ QE I H +++I R+++ +++ EE ++ ++ EE ++K+K H
Sbjct: 496 QEEKMWRQEEKI-----HEQEKI----REEEKRQEQEEMWRQEEKIREQEEIWRQKEKIH 546
Query: 265 SSS---KKSEDSLLRNS----DEEESASESE--LWK--GPLPETDEKSQEEE 305
+K E+ + R D+EE E E +W+ + E +EK +E+E
Sbjct: 547 EQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQE 598
Score = 35.4 bits (80), Expect = 0.066
Identities = 52/322 (16%), Positives = 136/322 (42%), Gaps = 28/322 (8%)
Query: 7 YDSDFSDDERCGESSKRKKRTVEDDLLLQKPFQKEKHGKVAHKQVAAELLDREEARNRRF 66
++ + E + K R E+ + Q+ EK K+ ++ E++ +E + RR
Sbjct: 373 WEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQE---EMMWEKEEKMRRQ 429
Query: 67 HLIAMDAYQRHTKFVNDYILYYGGKKEDFKRLGENDKTDLDVIRENHRFLWNEEDEMDMT 126
+ + ++ + ++++ KR E + + +E +W +E+++
Sbjct: 430 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 489
Query: 127 WEKRLAK-----KYYDKLFKEYCIADLSKYKENKFGFRWRVEKEVISGKGQFFCGNKYCD 181
EK + + +K+ ++ I + K +E + WR E+++ + + K +
Sbjct: 490 EEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEE--MWRQEEKIREQEEIWRQKEKIHE 547
Query: 182 KKEGLKSWEVNFGYIE---HGEKRNALV----------KLRLCQECSIKLNFHHRRKEIK 228
++E ++ E E H ++ K+R +E + R +E
Sbjct: 548 QEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEM 607
Query: 229 SKKRKDKTKKDCEESSHKKSRLSSAEEASKKKDKGHSSSKK---SEDSLLRNSDEEESAS 285
++++++K + E+ ++ ++ EE +++++ +K ++ +R +E
Sbjct: 608 TQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ 667
Query: 286 ESELW--KGPLPETDEKSQEEE 305
E ++W + + E +EK QE+E
Sbjct: 668 EEKMWEQEEKMCEQEEKMQEQE 689
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 42.0 bits (97), Expect = 7e-04
Identities = 48/232 (20%), Positives = 99/232 (42%), Gaps = 30/232 (12%)
Query: 91 KKEDFKRLGENDKTDLDVIRENHRFLWNEEDEM----DMTWEKRLAKKYYDKLF--KEYC 144
++E +R E + +R +W +E++M +M WEK + +++ KE
Sbjct: 333 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEK 392
Query: 145 IADLSKYKENKFGFRWRVEKEVISGKGQFFCGNKYCDKKEGLKSWEVNFGYIEHGEKRNA 204
I +L + + R + EK K + + +++ K W E EK
Sbjct: 393 IRELEEKMHEQEKIREQEEKRQEEEKIR----EQEKRQEQEAKMWRQEEKIREQEEKIRE 448
Query: 205 LVKLRLCQECSIKLNFHHRRKEIKSKKRKDKTKKDCEESSHKKSRLSSAEEASKKKDKGH 264
K QE I H +++I R+++ +++ EE ++ ++ EE ++K+K H
Sbjct: 449 QEKKMWRQEEKI-----HEQEKI----REEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMH 499
Query: 265 SSSKK---------SEDSLLRNSDEEESASESELWK--GPLPETDEKSQEEE 305
+K ++ +R +E+ E ++W+ + E +E +EEE
Sbjct: 500 EQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEE 551
Score = 39.3 bits (90), Expect = 0.005
Identities = 54/293 (18%), Positives = 129/293 (44%), Gaps = 31/293 (10%)
Query: 29 EDDLLLQKPFQKEKHGKVAHKQVAAELLDREEARNRRFHLIAMDAYQRHTKFVNDYILYY 88
E+ + Q+ EK K+ ++ E++ +E + RR + + ++ +
Sbjct: 348 EEKMRRQEEMMWEKEEKMRRQE---EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE 404
Query: 89 GGKKEDFKRLGENDKTDLDVIRENHRFLWNEEDEMDMTWEK--RLAKKYY---DKLFKEY 143
++++ KR E + + +E +W +E+++ EK KK + +K+ ++
Sbjct: 405 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQE 464
Query: 144 CIADLSKYKENKFGFRWRVEKEVISGKGQFFCGNKYCDKKEGLKSWEVNFGYIEHGEKRN 203
I + K +E + WR E+++ + + K +++E ++ E E
Sbjct: 465 KIREEEKRQEQEE--MWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEE----- 517
Query: 204 ALVKLRLCQECSIKLNFHHRRKEIKSKKRKDKTKKDCEESSHKKSRLSSAEEASKKKDKG 263
K+R +E + R+E K +++++ ++ EE H++ ++ E+ +++DK
Sbjct: 518 ---KIREQEEKIREQEEKMWRQEEKIREQEEMWRE--EEKMHEQEKIWEEEKRQEQEDKM 572
Query: 264 HSSSKK---------SEDSLLRNSDEEESASESELWK--GPLPETDEKSQEEE 305
+K ++ +R +E+ E ++WK + E +EK QE+E
Sbjct: 573 WRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQE 625
Score = 32.7 bits (73), Expect = 0.43
Identities = 42/222 (18%), Positives = 95/222 (42%), Gaps = 48/222 (21%)
Query: 91 KKEDFKRLGENDKTDLDVIRENHRFLWNEED---EMDMTWEKRLAKKYYDKLFKEYCIAD 147
++E R E + + IRE +W +E+ E + W + +K+++E +
Sbjct: 508 QEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEE----E 563
Query: 148 LSKYKENKFGFRWRVEKEVISGKGQFFCGNKYCDKKEGLKSWEVNFGYIEHGEKRNALVK 207
+ +E+K WR E+++ +++ K W E EKR
Sbjct: 564 KRQEQEDKM---WRQEEKI---------------REQEEKVWRQEEKIREQEEKR----- 600
Query: 208 LRLCQECSIKLNFHHRRKEIKSKKRKDKTKKDCEESSHKKSRLSSAEEASKKKDK--GHS 265
QE K+ ++E K +++++K ++ E+ ++ ++ EE ++++++ G
Sbjct: 601 ----QEQEEKM----WKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQ 652
Query: 266 SSKKSEDSLLRNSDEEESASESELWK--GPLPETDEKSQEEE 305
K E +E+ E +W+ + E ++K +E+E
Sbjct: 653 EEKMCE------QEEKMQEQEETMWRQEEKIREQEKKIREQE 688
>gi|169234949 CWF19-like 2, cell cycle control [Homo sapiens]
Length = 894
Score = 41.2 bits (95), Expect = 0.001
Identities = 32/129 (24%), Positives = 61/129 (47%), Gaps = 17/129 (13%)
Query: 182 KKEGLKSWEVNFGYIEHGEKRNALVKLR-----LCQECSIKLNFHHRRKEIKSKKRKDKT 236
+ E L+ + NF E E+R L +LR + + + ++ + +K KK+KDK
Sbjct: 29 RAEVLRQAKANF---EKEERRKELKRLRGEDTWMLPDVNERIEQFSQEHSVKKKKKKDKH 85
Query: 237 KKDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEESASESELWKGPLPE 296
K ++ KKS+ E+ ++ D SS + +++ + ++E A WK
Sbjct: 86 SKKAKKEKKKKSKKQKYEKNNESSDSSSSSEDEWVEAVPSQTPDKEKA-----WK----V 136
Query: 297 TDEKSQEEE 305
DEKS +++
Sbjct: 137 KDEKSGKDD 145
Score = 32.7 bits (73), Expect = 0.43
Identities = 24/117 (20%), Positives = 49/117 (41%), Gaps = 12/117 (10%)
Query: 196 IEHGEKRNALVKLRLCQECSIKLNFHHRRKEIKSKKRKD---------KTKKDCEESSHK 246
IE +++ + + ++ RRKE+K + +D + ++ +E S K
Sbjct: 18 IEERKEQTRNARAEVLRQAKANFEKEERRKELKRLRGEDTWMLPDVNERIEQFSQEHSVK 77
Query: 247 KSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEESASESELWKGPLP-ETDEKSQ 302
K + KK+K S K+ + N + S+S + W +P +T +K +
Sbjct: 78 KKKKKDKHSKKAKKEKKKKSKKQKYEK--NNESSDSSSSSEDEWVEAVPSQTPDKEK 132
>gi|21389511 zinc finger, matrin type 2 [Homo sapiens]
Length = 199
Score = 41.2 bits (95), Expect = 0.001
Identities = 40/170 (23%), Positives = 79/170 (46%), Gaps = 5/170 (2%)
Query: 119 EEDEMDMTWEKRLAKKYYDKLFK--EYCIADLSKYKENKFGFRWRVEKEVISGKG--QFF 174
++DE + EKRL ++ K K + +L ++++ K ++ K ++ K Q
Sbjct: 17 DKDEYEKLAEKRLTEEREKKDGKPVQPVKRELLRHRDYKVDLESKLGKTIVITKTTPQSE 76
Query: 175 CGNKYCDKKEGLKSWEVNFGYIEHGEKRNALVKLRLCQECSIKLNFHHRRKEIKSKKRKD 234
G YC+ + + +NF +G+K + + + E S L+ +R E+ KK ++
Sbjct: 77 MGGYYCNVCDCVVKDSINFLDHINGKKHQRNLGMSMRVERST-LDQVKKRFEVNKKKMEE 135
Query: 235 KTKKDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEESA 284
K K E K+ R + + KK+K +++E+ L D+E +A
Sbjct: 136 KQKDYDFEERMKELREEEEKAKAYKKEKQKEKKRRAEEDLTFEEDDEMAA 185
>gi|38788333 remodeling and spacing factor 1 [Homo sapiens]
Length = 1441
Score = 40.0 bits (92), Expect = 0.003
Identities = 28/90 (31%), Positives = 46/90 (51%), Gaps = 8/90 (8%)
Query: 223 RRKEIKSKKRKDKTKKDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEE 282
RR+ +++KR+ K+D E +KS L +E + + SSS+ E L +NS+++E
Sbjct: 1204 RRRSRRNQKRQINYKEDSESDGSQKS-LRRGKEIRRVHKRRLSSSESEESYLSKNSEDDE 1262
Query: 283 SASESE-------LWKGPLPETDEKSQEEE 305
A ES+ E DE+ +EEE
Sbjct: 1263 LAKESKRSVRKRGRSTDEYSEADEEEEEEE 1292
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 40.0 bits (92), Expect = 0.003
Identities = 24/74 (32%), Positives = 36/74 (48%), Gaps = 5/74 (6%)
Query: 224 RKEIKSKKRKDKTKKDCEESS-HKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEE 282
+KE K + K KK ++SS HK+ + EE S K + G S K+ + +N
Sbjct: 665 KKERSGKSHRHKKKKKHKKSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAP 724
Query: 283 SASESELWKGPLPE 296
+ SE +GP PE
Sbjct: 725 ADSE----RGPKPE 734
>gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo
sapiens]
Length = 482
Score = 39.7 bits (91), Expect = 0.004
Identities = 22/84 (26%), Positives = 46/84 (54%), Gaps = 6/84 (7%)
Query: 223 RRKEIKSKKRKDKTKKDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEE 282
+ KE +KKR+++ ++ +E ++ R EE K+++K K+ E++L + D+ E
Sbjct: 90 KEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEK-----KEKEEALQKMLDQAE 144
Query: 283 SASES-ELWKGPLPETDEKSQEEE 305
+ E+ W+ P P D + E++
Sbjct: 145 NELENGTTWQNPEPPVDFRVMEKD 168
Score = 28.9 bits (63), Expect = 6.2
Identities = 25/77 (32%), Positives = 37/77 (48%), Gaps = 15/77 (19%)
Query: 241 EESSHKKSRLSSAEEASKKK--------DKGHSSSKKSEDSLLRNSD-EEESASESELWK 291
E+ SHKK R + +E KK+ D G S ++ ED+ + EEE E E +
Sbjct: 11 EKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERE--R 68
Query: 292 GPLPE----TDEKSQEE 304
L E ++K+QEE
Sbjct: 69 QRLHEEWLLREQKAQEE 85
>gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo
sapiens]
Length = 1272
Score = 39.3 bits (90), Expect = 0.005
Identities = 24/83 (28%), Positives = 37/83 (44%)
Query: 206 VKLRLCQECSIKLNFHHRRKEIKSKKRKDKTKKDCEESSHKKSRLSSAEEASKKKDKGHS 265
+KL +E S +R E +K++DK +K +E K S +E +KK
Sbjct: 41 IKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEE 100
Query: 266 SSKKSEDSLLRNSDEEESASESE 288
KK E+ R +EE +A E
Sbjct: 101 ERKKQEEQAKRQQEEEAAAQMKE 123
Score = 38.5 bits (88), Expect = 0.008
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 3/78 (3%)
Query: 217 KLNFHHRRKEIKSKKRKDKTKKDCEESSHKKS---RLSSAEEASKKKDKGHSSSKKSEDS 273
+L R+KE K +K+KD+ K EE S KK + EE KK+++ ++ E +
Sbjct: 59 RLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAA 118
Query: 274 LLRNSDEEESASESELWK 291
EE E W+
Sbjct: 119 AQMKEKEESIQLHQEAWE 136
Score = 34.3 bits (77), Expect = 0.15
Identities = 31/98 (31%), Positives = 44/98 (44%), Gaps = 17/98 (17%)
Query: 224 RKEIKSKKRKDKT----KKDCEESSHKKSR--------LSSAEEASK----KKDKGHSSS 267
RK+ S + KD +KDC E S+ L++ +E SK KK +
Sbjct: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
Query: 268 KKSEDSLLRNSDEEESASESELWKGPLPETDEKSQEEE 305
+K ED + DEE+ +E E K E +K QEEE
Sbjct: 65 RKKEDKERKKKDEEKVKAEEESKKKE-EEEKKKHQEEE 101
Score = 32.0 bits (71), Expect = 0.73
Identities = 30/92 (32%), Positives = 43/92 (46%), Gaps = 12/92 (13%)
Query: 224 RKEIKSKKRKDKTKKDCEESSHKKSRLSSAEEASKKKD----KGHSSSKKSEDSLLRNSD 279
+KE+ SK +DK KK E+ KK ++ KKKD K SKK E+ +
Sbjct: 46 KKEV-SKAPEDK-KKRLEDDKRKKE-----DKERKKKDEEKVKAEEESKKKEEEEKKKHQ 98
Query: 280 EEESASESELWKGPLPETDEKSQEEEFDEYFQ 311
EEE + E K E + +Q +E +E Q
Sbjct: 99 EEERKKQEEQAKRQ-QEEEAAAQMKEKEESIQ 129
Score = 28.5 bits (62), Expect = 8.1
Identities = 15/47 (31%), Positives = 23/47 (48%)
Query: 261 DKGHSSSKKSEDSLLRNSDEEESASESELWKGPLPETDEKSQEEEFD 307
DK S ++L + +EEE +E+E G E +E +EE D
Sbjct: 1016 DKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSD 1062
>gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo
sapiens]
Length = 1272
Score = 39.3 bits (90), Expect = 0.005
Identities = 24/83 (28%), Positives = 37/83 (44%)
Query: 206 VKLRLCQECSIKLNFHHRRKEIKSKKRKDKTKKDCEESSHKKSRLSSAEEASKKKDKGHS 265
+KL +E S +R E +K++DK +K +E K S +E +KK
Sbjct: 41 IKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEE 100
Query: 266 SSKKSEDSLLRNSDEEESASESE 288
KK E+ R +EE +A E
Sbjct: 101 ERKKQEEQAKRQQEEEAAAQMKE 123
Score = 38.5 bits (88), Expect = 0.008
Identities = 23/78 (29%), Positives = 36/78 (46%), Gaps = 3/78 (3%)
Query: 217 KLNFHHRRKEIKSKKRKDKTKKDCEESSHKKS---RLSSAEEASKKKDKGHSSSKKSEDS 273
+L R+KE K +K+KD+ K EE S KK + EE KK+++ ++ E +
Sbjct: 59 RLEDDKRKKEDKERKKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAA 118
Query: 274 LLRNSDEEESASESELWK 291
EE E W+
Sbjct: 119 AQMKEKEESIQLHQEAWE 136
Score = 34.3 bits (77), Expect = 0.15
Identities = 31/98 (31%), Positives = 44/98 (44%), Gaps = 17/98 (17%)
Query: 224 RKEIKSKKRKDKT----KKDCEESSHKKSR--------LSSAEEASK----KKDKGHSSS 267
RK+ S + KD +KDC E S+ L++ +E SK KK +
Sbjct: 5 RKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLEDDK 64
Query: 268 KKSEDSLLRNSDEEESASESELWKGPLPETDEKSQEEE 305
+K ED + DEE+ +E E K E +K QEEE
Sbjct: 65 RKKEDKERKKKDEEKVKAEEESKKKE-EEEKKKHQEEE 101
Score = 32.0 bits (71), Expect = 0.73
Identities = 30/92 (32%), Positives = 43/92 (46%), Gaps = 12/92 (13%)
Query: 224 RKEIKSKKRKDKTKKDCEESSHKKSRLSSAEEASKKKD----KGHSSSKKSEDSLLRNSD 279
+KE+ SK +DK KK E+ KK ++ KKKD K SKK E+ +
Sbjct: 46 KKEV-SKAPEDK-KKRLEDDKRKKE-----DKERKKKDEEKVKAEEESKKKEEEEKKKHQ 98
Query: 280 EEESASESELWKGPLPETDEKSQEEEFDEYFQ 311
EEE + E K E + +Q +E +E Q
Sbjct: 99 EEERKKQEEQAKRQ-QEEEAAAQMKEKEESIQ 129
Score = 28.5 bits (62), Expect = 8.1
Identities = 15/47 (31%), Positives = 23/47 (48%)
Query: 261 DKGHSSSKKSEDSLLRNSDEEESASESELWKGPLPETDEKSQEEEFD 307
DK S ++L + +EEE +E+E G E +E +EE D
Sbjct: 1016 DKDSKDSMTEGENLEEDEEEEEGGAETEEQSGNESEVNEPEEEEGSD 1062
>gi|195976782 Paf1/RNA polymerase II complex component [Homo
sapiens]
Length = 710
Score = 38.5 bits (88), Expect = 0.008
Identities = 25/97 (25%), Positives = 43/97 (44%)
Query: 216 IKLNFHHRRKEIKSKKRKDKTKKDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLL 275
+K F ++K +KK++ K KK +E +K +L+ +E+ SK+ E
Sbjct: 218 LKRRFEIKKKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDK 277
Query: 276 RNSDEEESASESELWKGPLPETDEKSQEEEFDEYFQD 312
++ EE +E E K E K Q + E + D
Sbjct: 278 KSQAMEELKAEREKRKNRTAELLAKKQPLKTSEVYSD 314
Score = 37.0 bits (84), Expect = 0.023
Identities = 27/84 (32%), Positives = 42/84 (50%), Gaps = 10/84 (11%)
Query: 231 KRKDKTKKDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEESASESELW 290
K+K K +K ++ + KK +A S KD SS E+ + +SD S+S S
Sbjct: 112 KKKGKARKIEKKGTMKKQANKTASSGSSDKDSSAESS-APEEGEVSDSDSNSSSSSS--- 167
Query: 291 KGPLPETDEKSQEEEF-DEYFQDL 313
++D S++EEF D Y +DL
Sbjct: 168 -----DSDSSSEDEEFHDGYGEDL 186
Score = 34.7 bits (78), Expect = 0.11
Identities = 30/112 (26%), Positives = 50/112 (44%), Gaps = 8/112 (7%)
Query: 200 EKRNALVKLRLCQECSIKLNFHHRRKEIKSKKRKDKTKK------DCEESSHKKSRLSSA 253
EKR L K R + +K +KE K K+ +++ KK + + +SH K R S
Sbjct: 213 EKREVL-KRRFEIKKKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKR 271
Query: 254 EEASKKKDKGHSSSKKSEDSLLRNSDEEESASESELWKGPLPETDEKSQEEE 305
+E KK + K+E +N E A + L + DE+ +E++
Sbjct: 272 DEKLDKKSQA-MEELKAEREKRKNRTAELLAKKQPLKTSEVYSDDEEEEEDD 322
Score = 30.4 bits (67), Expect = 2.1
Identities = 69/281 (24%), Positives = 105/281 (37%), Gaps = 41/281 (14%)
Query: 12 SDDERCGESSKRKK----RTVEDDLLLQKPFQKEKHGKVAHKQVAAELLDREEARNRRFH 67
SDDE S+K KK R +E ++K K + K +AE EE
Sbjct: 100 SDDEWTFGSNKNKKKGKARKIEKKGTMKKQANKTASSGSSDKDSSAESSAPEEGEVSDSD 159
Query: 68 LIAMDAYQRHTKFVNDYILYYGGKKEDFKRLGENDKTDLDVIRENHRFLWNEEDEMDMTW 127
+ + D ++ G ED E D+ L+ + E R E E+
Sbjct: 160 SNSSSSSSDSDSSSEDEE-FHDGYGEDLMG-DEEDRARLEQMTEKER-----EQELFNRI 212
Query: 128 EKRLAKKYYDKLFKEYCIADLSKYKENKFGFRWRVEKEVISG--KGQFFCGNKYCDKKEG 185
EKR K ++ K+ A + KE K EK+ ++ + Q NK K
Sbjct: 213 EKREVLKRRFEIKKKLKTAKKKEKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRD 272
Query: 186 LKSWEVNFGYIEHGEKRNALVKLRLCQECSIKLNFHHRRKEIKSKKRKDKTKKDCEESSH 245
K +K A+ +L+ +E +R E+ +KK+ KT
Sbjct: 273 EKL----------DKKSQAMEELKAERE-----KRKNRTAELLAKKQPLKT--------- 308
Query: 246 KKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEESASE 286
S + S +E ++ DK SS K S +SDEEE E
Sbjct: 309 --SEVYSDDEEEEEDDK--SSEKSDRSSRTSSSDEEEEKEE 345
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 38.1 bits (87), Expect = 0.010
Identities = 25/86 (29%), Positives = 45/86 (52%), Gaps = 14/86 (16%)
Query: 224 RKEIKSKKRKDKTK-KDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEE 282
RK +K +K +++ D ++ S + + SSAE +S + G ++ E+ +EEE
Sbjct: 237 RKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEE------EEEE 290
Query: 283 SASESELWKGPLPETDEKSQEEEFDE 308
S SE E++E+ +EEE +E
Sbjct: 291 EGSTSE-------ESEEEEEEEEEEE 309
Score = 30.8 bits (68), Expect = 1.6
Identities = 21/81 (25%), Positives = 41/81 (50%), Gaps = 5/81 (6%)
Query: 230 KKRKDKTKKDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEE-----ESA 284
++ +++ +++ E S+ ++S EE ++++ G +S + SE S S+EE E
Sbjct: 280 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 339
Query: 285 SESELWKGPLPETDEKSQEEE 305
+E+ L P D S E E
Sbjct: 340 NENHLLVVPESRFDRDSGESE 360
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 38.1 bits (87), Expect = 0.010
Identities = 25/86 (29%), Positives = 45/86 (52%), Gaps = 14/86 (16%)
Query: 224 RKEIKSKKRKDKTK-KDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEE 282
RK +K +K +++ D ++ S + + SSAE +S + G ++ E+ +EEE
Sbjct: 247 RKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEE------EEEE 300
Query: 283 SASESELWKGPLPETDEKSQEEEFDE 308
S SE E++E+ +EEE +E
Sbjct: 301 EGSTSE-------ESEEEEEEEEEEE 319
Score = 30.8 bits (68), Expect = 1.6
Identities = 21/81 (25%), Positives = 41/81 (50%), Gaps = 5/81 (6%)
Query: 230 KKRKDKTKKDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEE-----ESA 284
++ +++ +++ E S+ ++S EE ++++ G +S + SE S S+EE E
Sbjct: 290 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 349
Query: 285 SESELWKGPLPETDEKSQEEE 305
+E+ L P D S E E
Sbjct: 350 NENHLLVVPESRFDRDSGESE 370
Score = 29.6 bits (65), Expect = 3.6
Identities = 28/113 (24%), Positives = 48/113 (42%), Gaps = 16/113 (14%)
Query: 197 EHGEKRNALVKLRLCQECSIKLNFHHRRKEIKSKKRKDKTKKDCEESSH-----KKSRLS 251
+ GE+ ++L ++ Q+ S K HHR+ E KRK+K C SH K +R+
Sbjct: 75 DRGEEDDSLA-IKPPQQMSRKEKVHHRKDE----KRKEK----CRHHSHSAEGGKHARVK 125
Query: 252 SAEEASKKKDKGHSSSKKSEDSLLRNSDEEESASESELWKGPLPETDEKSQEE 304
E +K+ + + E R E + S + L + + K + E
Sbjct: 126 EREHERRKRHREEQDKARREWE--RQKRREMAREHSRRERDRLEQLERKRERE 176
>gi|192807334 arsenate resistance protein 2 isoform d [Homo sapiens]
Length = 872
Score = 38.1 bits (87), Expect = 0.010
Identities = 23/81 (28%), Positives = 43/81 (53%), Gaps = 6/81 (7%)
Query: 234 DKTKK---DCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEESASESELW 290
DKTKK D ++ K+ A+++SKK+++ HS ++ + S+ E + ++E
Sbjct: 323 DKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEE 382
Query: 291 KGPLPET---DEKSQEEEFDE 308
K E EK +EEE+++
Sbjct: 383 KEEAEEALKEKEKPKEEEWEK 403
Score = 32.3 bits (72), Expect = 0.56
Identities = 24/89 (26%), Positives = 43/89 (48%), Gaps = 6/89 (6%)
Query: 223 RRKEIKSKKRKDKTKKDCEESSHKKSRLSSAE-EASKKKDKGHSSSKKSEDSLLR----- 276
R+ K +K++D + + + S+ K++ S + + +KK+ +KKS R
Sbjct: 300 RKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGD 359
Query: 277 NSDEEESASESELWKGPLPETDEKSQEEE 305
+S +E S SESE +EK + EE
Sbjct: 360 DSFDEGSVSESESESESGQAEEEKEEAEE 388
>gi|58331218 arsenate resistance protein 2 isoform a [Homo sapiens]
Length = 876
Score = 38.1 bits (87), Expect = 0.010
Identities = 23/81 (28%), Positives = 43/81 (53%), Gaps = 6/81 (7%)
Query: 234 DKTKK---DCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEESASESELW 290
DKTKK D ++ K+ A+++SKK+++ HS ++ + S+ E + ++E
Sbjct: 323 DKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGDDSFDEGSVSESESESESGQAEEE 382
Query: 291 KGPLPET---DEKSQEEEFDE 308
K E EK +EEE+++
Sbjct: 383 KEEAEEALKEKEKPKEEEWEK 403
Score = 32.3 bits (72), Expect = 0.56
Identities = 24/89 (26%), Positives = 43/89 (48%), Gaps = 6/89 (6%)
Query: 223 RRKEIKSKKRKDKTKKDCEESSHKKSRLSSAE-EASKKKDKGHSSSKKSEDSLLR----- 276
R+ K +K++D + + + S+ K++ S + + +KK+ +KKS R
Sbjct: 300 RKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKHSGD 359
Query: 277 NSDEEESASESELWKGPLPETDEKSQEEE 305
+S +E S SESE +EK + EE
Sbjct: 360 DSFDEGSVSESESESESGQAEEEKEEAEE 388
>gi|4504487 histidine rich calcium binding protein precursor [Homo
sapiens]
Length = 699
Score = 38.1 bits (87), Expect = 0.010
Identities = 32/101 (31%), Positives = 41/101 (40%), Gaps = 8/101 (7%)
Query: 212 QECSIKLNFHHRRKEIKSKKRKDKTKKDCEESSHKKSRLSSAEEASKKKDKG----HSSS 267
Q SIK HH K R K D EE K+ S EE + ++G H S
Sbjct: 454 QRGSIKEMSHHPPGHTVVKDRSHLRKDDSEEEKEKEEDPGSHEEDDESSEQGEKGTHHGS 513
Query: 268 KKSEDSLLRNSDEEESASESELWKGPLPETDEKSQEEEFDE 308
+ ED DEEE S + E E+ +EEE +E
Sbjct: 514 RDQEDE----EDEEEGHGLSLNQEEEEEEDKEEEEEEEDEE 550
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 38.1 bits (87), Expect = 0.010
Identities = 25/86 (29%), Positives = 45/86 (52%), Gaps = 14/86 (16%)
Query: 224 RKEIKSKKRKDKTK-KDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEE 282
RK +K +K +++ D ++ S + + SSAE +S + G ++ E+ +EEE
Sbjct: 238 RKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEE------EEEE 291
Query: 283 SASESELWKGPLPETDEKSQEEEFDE 308
S SE E++E+ +EEE +E
Sbjct: 292 EGSTSE-------ESEEEEEEEEEEE 310
Score = 30.8 bits (68), Expect = 1.6
Identities = 21/81 (25%), Positives = 41/81 (50%), Gaps = 5/81 (6%)
Query: 230 KKRKDKTKKDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEE-----ESA 284
++ +++ +++ E S+ ++S EE ++++ G +S + SE S S+EE E
Sbjct: 281 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 340
Query: 285 SESELWKGPLPETDEKSQEEE 305
+E+ L P D S E E
Sbjct: 341 NENHLLVVPESRFDRDSGESE 361
Score = 29.6 bits (65), Expect = 3.6
Identities = 28/120 (23%), Positives = 53/120 (44%), Gaps = 18/120 (15%)
Query: 197 EHGEKRNALVKLRLCQECSIKLNFHHRRKEIKSKKRKDK-----TKKDCEESSHKKSRLS 251
+ GE+ ++L ++ Q+ S K HHR+ E KRK+K +K+ E K+ R
Sbjct: 75 DRGEEDDSLA-IKPPQQMSRKEKVHHRKDE----KRKEKKHARVKEKEREHERRKRHREE 129
Query: 252 SAE-----EASKKKDKGHSSSKKSED---SLLRNSDEEESASESELWKGPLPETDEKSQE 303
+ E K+++ S++ D L R + E E + + E + +++E
Sbjct: 130 QDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEE 189
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 38.1 bits (87), Expect = 0.010
Identities = 25/86 (29%), Positives = 45/86 (52%), Gaps = 14/86 (16%)
Query: 224 RKEIKSKKRKDKTK-KDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEE 282
RK +K +K +++ D ++ S + + SSAE +S + G ++ E+ +EEE
Sbjct: 247 RKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEE------EEEE 300
Query: 283 SASESELWKGPLPETDEKSQEEEFDE 308
S SE E++E+ +EEE +E
Sbjct: 301 EGSTSE-------ESEEEEEEEEEEE 319
Score = 30.8 bits (68), Expect = 1.6
Identities = 25/117 (21%), Positives = 53/117 (45%), Gaps = 9/117 (7%)
Query: 197 EHGEKRNALVKLRLCQECSIKLNFHHR----RKEIKSKKRKDKTKKDCEESSHKKSRLSS 252
+ GE+ ++L ++ Q+ S K HHR RKE K + K+K ++ H++ + +
Sbjct: 75 DRGEEDDSLA-IKPPQQMSRKEKVHHRKDEKRKEKKHARVKEKEREHERRKRHREEQDKA 133
Query: 253 AEEASKKK----DKGHSSSKKSEDSLLRNSDEEESASESELWKGPLPETDEKSQEEE 305
E ++K + HS ++ D + D E + + E ++ +E++
Sbjct: 134 RREWERQKRREMAREHSRRERGNDGVCLFRDRLEQLERKRERERKMREQQKEQREQK 190
Score = 30.8 bits (68), Expect = 1.6
Identities = 21/81 (25%), Positives = 41/81 (50%), Gaps = 5/81 (6%)
Query: 230 KKRKDKTKKDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEE-----ESA 284
++ +++ +++ E S+ ++S EE ++++ G +S + SE S S+EE E
Sbjct: 290 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 349
Query: 285 SESELWKGPLPETDEKSQEEE 305
+E+ L P D S E E
Sbjct: 350 NENHLLVVPESRFDRDSGESE 370
Score = 28.5 bits (62), Expect = 8.1
Identities = 24/106 (22%), Positives = 46/106 (43%), Gaps = 12/106 (11%)
Query: 220 FHHRRKEIKSKKRKD-KTKKDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNS 278
F R ++++ K+ ++ K ++ +E +K R AEE K+++ S S
Sbjct: 162 FRDRLEQLERKRERERKMREQQKEQREQKERERRAEERRKEREARREVSAHHRTMREDYS 221
Query: 279 DEEESASES-----------ELWKGPLPETDEKSQEEEFDEYFQDL 313
D+ +++ S EL G P +EK +E + QD+
Sbjct: 222 DKVKASHWSRSPPRPPRERFELGDGRKPVKEEKMEERDLLSDLQDI 267
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 38.1 bits (87), Expect = 0.010
Identities = 25/86 (29%), Positives = 45/86 (52%), Gaps = 14/86 (16%)
Query: 224 RKEIKSKKRKDKTK-KDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEE 282
RK +K +K +++ D ++ S + + SSAE +S + G ++ E+ +EEE
Sbjct: 215 RKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEE------EEEE 268
Query: 283 SASESELWKGPLPETDEKSQEEEFDE 308
S SE E++E+ +EEE +E
Sbjct: 269 EGSTSE-------ESEEEEEEEEEEE 287
Score = 32.0 bits (71), Expect = 0.73
Identities = 22/108 (20%), Positives = 47/108 (43%), Gaps = 4/108 (3%)
Query: 197 EHGEKRNALVKLRLCQECSIKLNFHHRRKEIKSKKRKDKTKKDCEESSHKKSRLSSAEEA 256
+ GE+ ++L ++ Q+ S K HHR+ E + +KR+ ++ K +R+ E
Sbjct: 41 DRGEEDDSLA-IKPPQQMSRKEKVHHRKDEKRKEKRRHRSH---SAEGGKHARVKEKERE 96
Query: 257 SKKKDKGHSSSKKSEDSLLRNSDEEESASESELWKGPLPETDEKSQEE 304
+++ + K+ R E + S + L + + K + E
Sbjct: 97 HERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERE 144
Score = 30.8 bits (68), Expect = 1.6
Identities = 21/81 (25%), Positives = 41/81 (50%), Gaps = 5/81 (6%)
Query: 230 KKRKDKTKKDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEE-----ESA 284
++ +++ +++ E S+ ++S EE ++++ G +S + SE S S+EE E
Sbjct: 258 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 317
Query: 285 SESELWKGPLPETDEKSQEEE 305
+E+ L P D S E E
Sbjct: 318 NENHLLVVPESRFDRDSGESE 338
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 38.1 bits (87), Expect = 0.010
Identities = 25/86 (29%), Positives = 45/86 (52%), Gaps = 14/86 (16%)
Query: 224 RKEIKSKKRKDKTK-KDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEE 282
RK +K +K +++ D ++ S + + SSAE +S + G ++ E+ +EEE
Sbjct: 204 RKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEE------EEEE 257
Query: 283 SASESELWKGPLPETDEKSQEEEFDE 308
S SE E++E+ +EEE +E
Sbjct: 258 EGSTSE-------ESEEEEEEEEEEE 276
Score = 30.8 bits (68), Expect = 1.6
Identities = 21/81 (25%), Positives = 41/81 (50%), Gaps = 5/81 (6%)
Query: 230 KKRKDKTKKDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEE-----ESA 284
++ +++ +++ E S+ ++S EE ++++ G +S + SE S S+EE E
Sbjct: 247 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 306
Query: 285 SESELWKGPLPETDEKSQEEE 305
+E+ L P D S E E
Sbjct: 307 NENHLLVVPESRFDRDSGESE 327
Score = 29.6 bits (65), Expect = 3.6
Identities = 28/120 (23%), Positives = 53/120 (44%), Gaps = 18/120 (15%)
Query: 197 EHGEKRNALVKLRLCQECSIKLNFHHRRKEIKSKKRKDK-----TKKDCEESSHKKSRLS 251
+ GE+ ++L ++ Q+ S K HHR+ E KRK+K +K+ E K+ R
Sbjct: 41 DRGEEDDSLA-IKPPQQMSRKEKVHHRKDE----KRKEKKHARVKEKEREHERRKRHREE 95
Query: 252 SAE-----EASKKKDKGHSSSKKSED---SLLRNSDEEESASESELWKGPLPETDEKSQE 303
+ E K+++ S++ D L R + E E + + E + +++E
Sbjct: 96 QDKARREWERQKRREMAREHSRRERDRLEQLERKRERERKMREQQKEQREQKERERRAEE 155
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 38.1 bits (87), Expect = 0.010
Identities = 25/86 (29%), Positives = 45/86 (52%), Gaps = 14/86 (16%)
Query: 224 RKEIKSKKRKDKTK-KDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEE 282
RK +K +K +++ D ++ S + + SSAE +S + G ++ E+ +EEE
Sbjct: 249 RKPVKEEKMEERDLLSDLQDISDSERKTSSAESSSAESGSGSEEEEEEEE------EEEE 302
Query: 283 SASESELWKGPLPETDEKSQEEEFDE 308
S SE E++E+ +EEE +E
Sbjct: 303 EGSTSE-------ESEEEEEEEEEEE 321
Score = 32.0 bits (71), Expect = 0.73
Identities = 22/108 (20%), Positives = 47/108 (43%), Gaps = 4/108 (3%)
Query: 197 EHGEKRNALVKLRLCQECSIKLNFHHRRKEIKSKKRKDKTKKDCEESSHKKSRLSSAEEA 256
+ GE+ ++L ++ Q+ S K HHR+ E + +KR+ ++ K +R+ E
Sbjct: 75 DRGEEDDSLA-IKPPQQMSRKEKVHHRKDEKRKEKRRHRSH---SAEGGKHARVKEKERE 130
Query: 257 SKKKDKGHSSSKKSEDSLLRNSDEEESASESELWKGPLPETDEKSQEE 304
+++ + K+ R E + S + L + + K + E
Sbjct: 131 HERRKRHREEQDKARREWERQKRREMAREHSRRERDRLEQLERKRERE 178
Score = 30.8 bits (68), Expect = 1.6
Identities = 21/81 (25%), Positives = 41/81 (50%), Gaps = 5/81 (6%)
Query: 230 KKRKDKTKKDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEE-----ESA 284
++ +++ +++ E S+ ++S EE ++++ G +S + SE S S+EE E
Sbjct: 292 EEEEEEEEEEEEGSTSEESEEEEEEEEEEEEETGSNSEEASEQSAEEVSEEEMSEDEERE 351
Query: 285 SESELWKGPLPETDEKSQEEE 305
+E+ L P D S E E
Sbjct: 352 NENHLLVVPESRFDRDSGESE 372
>gi|239756568 PREDICTED: similar to BCL2-associated transcription
factor 1 [Homo sapiens]
Length = 869
Score = 37.7 bits (86), Expect = 0.013
Identities = 30/105 (28%), Positives = 49/105 (46%), Gaps = 7/105 (6%)
Query: 207 KLRLCQECSIKLNFHHRRKEIKSKKRKDKTKKDCEESSHKKSRLSSAEEASKKKDKGHSS 266
KLR C ++ + HRRKE +SK+R D +K E +K + + K K S
Sbjct: 683 KLR-CDSADLRHDIDHRRKE-RSKERGD-SKGSRESRGSRKQEKTPKDYKEYKSYKDDSK 739
Query: 267 SKKSEDSLLRNSDEEESASESELWKGPLPETDEKSQEEEFDEYFQ 311
K+ +D L +S +S S + + +K +EEEF + +
Sbjct: 740 HKREQDHSLSSSSSASPSSPSSREE----KESKKEREEEFKTHHE 780
Score = 32.0 bits (71), Expect = 0.73
Identities = 29/89 (32%), Positives = 41/89 (46%), Gaps = 7/89 (7%)
Query: 228 KSKKRKDKTKKDCEESSHKKSRLSSAEEASKKKDKGHSSS--KKSEDSLLRNSDEEES-A 284
+S+ R K + + S +SR S S + SSS KS S R S E+++
Sbjct: 107 RSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKK 166
Query: 285 SESELW-KGPLPETDEKSQEEEFDEYFQD 312
+E EL + PL KSQEE D + D
Sbjct: 167 AEGELQEESPL---KSKSQEEPKDTFEHD 192
>gi|169218320 PREDICTED: similar to BCL2-associated transcription
factor 1 isoform 2 [Homo sapiens]
Length = 869
Score = 37.7 bits (86), Expect = 0.013
Identities = 30/105 (28%), Positives = 49/105 (46%), Gaps = 7/105 (6%)
Query: 207 KLRLCQECSIKLNFHHRRKEIKSKKRKDKTKKDCEESSHKKSRLSSAEEASKKKDKGHSS 266
KLR C ++ + HRRKE +SK+R D +K E +K + + K K S
Sbjct: 683 KLR-CDSADLRHDIDHRRKE-RSKERGD-SKGSRESRGSRKQEKTPKDYKEYKSYKDDSK 739
Query: 267 SKKSEDSLLRNSDEEESASESELWKGPLPETDEKSQEEEFDEYFQ 311
K+ +D L +S +S S + + +K +EEEF + +
Sbjct: 740 HKREQDHSLSSSSSASPSSPSSREE----KESKKEREEEFKTHHE 780
Score = 30.0 bits (66), Expect = 2.8
Identities = 22/86 (25%), Positives = 35/86 (40%), Gaps = 1/86 (1%)
Query: 228 KSKKRKDKTKKDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSL-LRNSDEEESASE 286
+S+ R K + + S +SR S S + SSS S+ + R +E+ +
Sbjct: 107 RSRSRSPKRRSVSSQRSRSRSRRSYRSSRSPRSSSSRSSSPYSKSPVSKRRGSQEKQTKK 166
Query: 287 SELWKGPLPETDEKSQEEEFDEYFQD 312
+E KSQEE D + D
Sbjct: 167 AEGEPQEESPLKSKSQEEPKDTFEHD 192
>gi|11968023 zinc finger protein 106 homolog [Homo sapiens]
Length = 1883
Score = 37.7 bits (86), Expect = 0.013
Identities = 26/87 (29%), Positives = 41/87 (47%), Gaps = 4/87 (4%)
Query: 219 NFHHRRKEIKSKKRKDKTKKDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNS 278
+FH +E+K + T+ S + + LSS + ++ KG+S S+ S LR S
Sbjct: 1256 SFHEPSQELKFSVEQRNTRNRENSPSSQSAGLSSINKEGEEPTKGNSGSEACTSSFLRLS 1315
Query: 279 DEEESASESELWKGPLPETDEKSQEEE 305
ASE+ L K P D+ Q+ E
Sbjct: 1316 ----FASETPLEKEPHSPADQPEQQAE 1338
>gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens]
Length = 1312
Score = 37.7 bits (86), Expect = 0.013
Identities = 25/89 (28%), Positives = 44/89 (49%), Gaps = 6/89 (6%)
Query: 223 RRKEIKSKKRKDKTKKDC--EESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDE 280
+ KE+ KK +D D ++++ L+ EA ++K K + K ED ++E
Sbjct: 485 QEKEVNIKKPEDNENLDDKDDDTTRVDESLNIKVEAEEEKAKSGDETNKEEDEDDEEAEE 544
Query: 281 EESASESELWKGPLPETDEKSQEEEFDEY 309
EE E E + + D+ ++EEEF+ Y
Sbjct: 545 EEEEEEEEEDE----DDDDNNEEEEFECY 569
Score = 33.5 bits (75), Expect = 0.25
Identities = 41/188 (21%), Positives = 73/188 (38%), Gaps = 30/188 (15%)
Query: 130 RLAKKYYDKLFKEYCIADLSKYKENKFGFRWRVEKEVISGKGQFFCGNKYCDKKEGLKSW 189
+ A K Y F+EYC + F+ + ++V+ NK C + E +K
Sbjct: 383 KCAYKKYLYGFEEYC-------RSANIEFQMALPEKVV---------NKQCKECENVKEI 426
Query: 190 EVN------FGYIEHGEKRNALVKLRLCQECSIKLNFHHRRKEIKSKKRKDKTKKDC--- 240
+V I+ E+RN + + E I+ R++ IK K +
Sbjct: 427 KVKEENETEIKEIKMEEERNIIPREEKPIEDEIE-----RKENIKPSLGSKKNLLESIPT 481
Query: 241 EESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEESASESELWKGPLPETDEK 300
K+ + E+ DK +++ E ++ EEE A + E DE+
Sbjct: 482 HSDQEKEVNIKKPEDNENLDDKDDDTTRVDESLNIKVEAEEEKAKSGDETNKEEDEDDEE 541
Query: 301 SQEEEFDE 308
++EEE +E
Sbjct: 542 AEEEEEEE 549
Score = 30.8 bits (68), Expect = 1.6
Identities = 62/300 (20%), Positives = 108/300 (36%), Gaps = 48/300 (16%)
Query: 9 SDFSDDERCGESSKRKKRTVEDDLLLQKPFQKEKHGKVAHKQVAAELLDREEARNRRFHL 68
+D E SS ++ V DL++ KP K +V +E D EE +
Sbjct: 746 NDLISKEEQNSSSLLEENKVHADLVISKPVSKSPERLRKDIEVLSEDTDYEEDEVTK--- 802
Query: 69 IAMDAYQRHTKFVNDYILYYGGKKEDFKRLGENDKTDLDVIRENHRFLWNEEDEMDMTWE 128
K++D K+ DK+ I+ R N E+ +
Sbjct: 803 ----------------------KRKDVKK-DTTDKSSKPQIKRGKRRYCNTEECLKTGSP 839
Query: 129 KRLAKKYYDKLFKEYCIADLSKYKENKFGFRWRVEKEVISGKGQFFCGNKYCDKKEGLKS 188
+ +K +K + C+ + S ++ E+E + N +K++ L++
Sbjct: 840 GKKEEKAKNK--ESLCMENSSNSSSDED------EEETKAKMTPTKKYNGLEEKRKSLRT 891
Query: 189 WEVNFGYIEHGEKRNALVKLRLCQECSIKLNFHHRRKEIKSKKRKD---KTKKDCEESSH 245
G+ E EKR L+ N R + ++K RKD + + +
Sbjct: 892 TGFYSGFSEVAEKRIKLLN-----------NSDERLQNSRAKDRKDVWSSIQGQWPKKTL 940
Query: 246 KKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEESASESELWKGPLPETDEKSQEEE 305
K+ S EA+ +E+SL ++EE + EL K P D K EE+
Sbjct: 941 KELFSDSDTEAAASPPHPAPEEGVAEESLQTVAEEESCSPSVELEKPPPVNVDSKPIEEK 1000
>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
Length = 248
Score = 37.7 bits (86), Expect = 0.013
Identities = 42/197 (21%), Positives = 83/197 (42%), Gaps = 42/197 (21%)
Query: 126 TWEKRLAKKYYDKLFKEYCIADLSKYKENKFGFRWRVEKEVISGKGQFFCGNKYCDKKEG 185
TWE+ + K+ +K +A+ E K W+ KE+ + + GN+ KK
Sbjct: 40 TWEE-VKKQLENKKTGSKALAEF----EEKMNENWK--KELEKSREKLLSGNESSSKKR- 91
Query: 186 LKSWEVNFGYIEHGEKRNALVKLRLCQECSIKLNF-----------HHRRKEIKSKKRKD 234
E +KR K + C+ S + +++ + KK+K+
Sbjct: 92 -----------ERKKKR----KKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKN 136
Query: 235 KTKKDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEESASESELWKGPL 294
++ K + S+H+ S ++E+ KKK K ++K +D + ++S + +
Sbjct: 137 RSYKSSQSSTHESE--SESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDK------ 188
Query: 295 PETDEKSQEEEFDEYFQ 311
P + E S E +++E Q
Sbjct: 189 PLSSESSSESDYEEDVQ 205
Score = 30.8 bits (68), Expect = 1.6
Identities = 42/190 (22%), Positives = 77/190 (40%), Gaps = 20/190 (10%)
Query: 96 KRLGENDKTDLDVIRENHRFLWNEEDEMDMTWEKRLAKKYYDKLFKEYCIADLSKY---- 151
+++ EN K +L+ RE + L E K+ KK + +D S
Sbjct: 63 EKMNENWKKELEKSRE--KLLSGNESSSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDS 120
Query: 152 --KENKFGFRWRVEKEVISGKGQFFCGNKYCDKKEGLKSWEVNFGYIEHGEKRNALVKLR 209
+E K G R + +K Q + KE +K + + E + +L K R
Sbjct: 121 EDEEKKQGKRRKKKKNRSYKSSQSSTHESESESKESVKKKKKSKDETEKEKDVRSLSKKR 180
Query: 210 ---------LCQECSIKLNFHHRRKEIKSKKRKDKTKKDCEESSHKKSRLSSAEEASKKK 260
L E S + ++ +++++KK++ +++ + KK + ++ SKKK
Sbjct: 181 KKSYPDDKPLSSESSSESDYE---EDVQAKKKRRCEEREQAKEKVKKKKKKQHKKHSKKK 237
Query: 261 DKGHSSSKKS 270
K SS KS
Sbjct: 238 KKKSGSSHKS 247
>gi|46852388 cell-cycle and apoptosis regulatory protein 1 [Homo
sapiens]
Length = 1150
Score = 37.4 bits (85), Expect = 0.017
Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 7/83 (8%)
Query: 226 EIKSKKRKDKTKKDCEESSHKKSRLSSAEEASKKKDK-GHSSSKKSEDSLLRNSDEEESA 284
E + KK KDK K E K+ R +E K+ K G KK + + D+ +
Sbjct: 795 EKEDKKEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDRDERKKEDKRKDD 854
Query: 285 SESELWKGPLPETDEKSQEEEFD 307
S+ + ET+E + ++E+D
Sbjct: 855 SKDD------DETEEDNNQDEYD 871
Score = 37.4 bits (85), Expect = 0.017
Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 6/88 (6%)
Query: 223 RRKEIKSKK--RKDKTK-KDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSD 279
+ K+ KSKK RKDK + +D E K R S ++ KK+D+ +K ED +S
Sbjct: 800 KEKDKKSKKDERKDKKEERDDETDEPKPKRRKSGDDKDKKEDR---DERKKEDKRKDDSK 856
Query: 280 EEESASESELWKGPLPETDEKSQEEEFD 307
+++ E P E++++EE D
Sbjct: 857 DDDETEEDNNQDEYDPMEAEEAEDEEDD 884
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 37.4 bits (85), Expect = 0.017
Identities = 27/118 (22%), Positives = 50/118 (42%), Gaps = 3/118 (2%)
Query: 197 EHGEKRNALVKLRLCQECSIKLNFHHRRKEIKSKKRKDKTKKDCEESSHKKSRLS-SAEE 255
+ G + K R +E K +RK+ + KKR+ + K++ E ++ R EE
Sbjct: 108 QRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEE 167
Query: 256 ASKKKDKGHSSSKKSEDSLLRNSDEEESASESELWKGPLPETDEKSQEEEFDEYFQDL 313
KK+++ KK + R ++E E K + D K+ + + F+ L
Sbjct: 168 REKKRERNRKERKKERERKERRERKKERKKERR--KKKERKKDRKTDRQTDSQVFRPL 223
Score = 34.7 bits (78), Expect = 0.11
Identities = 18/80 (22%), Positives = 37/80 (46%)
Query: 223 RRKEIKSKKRKDKTKKDCEESSHKKSRLSSAEEASKKKDKGHSSSKKSEDSLLRNSDEEE 282
RRK K KK++++ ++ E KK R E +++++ +K + R ++E
Sbjct: 94 RRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKER 153
Query: 283 SASESELWKGPLPETDEKSQ 302
E + K E ++K +
Sbjct: 154 GKRERKRKKRKKEEREKKRE 173
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.132 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,906,678
Number of Sequences: 37866
Number of extensions: 620963
Number of successful extensions: 6531
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 246
Number of HSP's successfully gapped in prelim test: 304
Number of HSP's that attempted gapping in prelim test: 3885
Number of HSP's gapped (non-prelim): 2249
length of query: 315
length of database: 18,247,518
effective HSP length: 102
effective length of query: 213
effective length of database: 14,385,186
effective search space: 3064044618
effective search space used: 3064044618
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.