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Search of human proteins with 24308352
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24308352 DMRT-like family B with proline-rich C-terminal, 1
[Homo sapiens]
(342 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24308352 DMRT-like family B with proline-rich C-terminal, 1 [... 725 0.0
gi|154146231 DMRT-like family A2 [Homo sapiens] 100 3e-21
gi|11056048 doublesex and mab-3 related transcription factor 3 [... 91 2e-18
gi|170763515 DMRT-like family A1 [Homo sapiens] 89 7e-18
gi|62241026 doublesex and mab-3 related transcription factor 1 [... 87 3e-17
gi|195947401 doublesex and mab-3 related transcription factor 2 ... 80 2e-15
gi|5729806 doublesex and mab-3 related transcription factor 2 is... 80 2e-15
gi|153945850 doublesex and mab-3 related transcription factor 2 ... 80 2e-15
gi|94536830 DMRT-like family C2 [Homo sapiens] 74 2e-13
gi|119395760 diaphanous 1 isoform 2 [Homo sapiens] 70 4e-12
gi|119395758 diaphanous 1 isoform 1 [Homo sapiens] 70 4e-12
gi|160707881 formin 2 [Homo sapiens] 70 4e-12
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 65 7e-11
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ... 63 3e-10
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 60 2e-09
gi|239757043 PREDICTED: functional smad suppressing element 18 [... 59 6e-09
gi|239751555 PREDICTED: functional smad suppressing element 18 [... 59 6e-09
gi|239746067 PREDICTED: functional smad suppressing element 18 [... 59 6e-09
gi|210032580 SET domain containing 1B [Homo sapiens] 58 1e-08
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 58 1e-08
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 58 1e-08
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 58 1e-08
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 57 2e-08
gi|119829187 alpha 1 type XVII collagen [Homo sapiens] 57 2e-08
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 57 2e-08
gi|21955170 single stranded DNA binding protein 3 isoform a [Hom... 57 2e-08
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 57 2e-08
gi|56118221 amyloid beta (A4) precursor protein-binding, family ... 57 2e-08
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 57 2e-08
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 57 3e-08
>gi|24308352 DMRT-like family B with proline-rich C-terminal, 1
[Homo sapiens]
Length = 342
Score = 725 bits (1872), Expect = 0.0
Identities = 342/342 (100%), Positives = 342/342 (100%)
Query: 1 MADKMVRTPKCSRCRNHGFLVPVKGHAGKCRWKQCLCEKCYLISERQKIMAAQKVLKTQA 60
MADKMVRTPKCSRCRNHGFLVPVKGHAGKCRWKQCLCEKCYLISERQKIMAAQKVLKTQA
Sbjct: 1 MADKMVRTPKCSRCRNHGFLVPVKGHAGKCRWKQCLCEKCYLISERQKIMAAQKVLKTQA 60
Query: 61 AEEEQEAALCAQGPKQASGAAAAAPAPVPVPAASLRPLSPGTPSGDADPGPEGRAAACFF 120
AEEEQEAALCAQGPKQASGAAAAAPAPVPVPAASLRPLSPGTPSGDADPGPEGRAAACFF
Sbjct: 61 AEEEQEAALCAQGPKQASGAAAAAPAPVPVPAASLRPLSPGTPSGDADPGPEGRAAACFF 120
Query: 121 EQPPRGRNPGPRALQPVLGGRSHVEPSERAAVAMPSLAGPPFGAEAAGSGYPGPLDLRRP 180
EQPPRGRNPGPRALQPVLGGRSHVEPSERAAVAMPSLAGPPFGAEAAGSGYPGPLDLRRP
Sbjct: 121 EQPPRGRNPGPRALQPVLGGRSHVEPSERAAVAMPSLAGPPFGAEAAGSGYPGPLDLRRP 180
Query: 181 MRTVPGPLFTDFVRPLNINPDRALGPEYPGGSSMHPYCPFPLGYLDAPPGVPLQQGFRHV 240
MRTVPGPLFTDFVRPLNINPDRALGPEYPGGSSMHPYCPFPLGYLDAPPGVPLQQGFRHV
Sbjct: 181 MRTVPGPLFTDFVRPLNINPDRALGPEYPGGSSMHPYCPFPLGYLDAPPGVPLQQGFRHV 240
Query: 241 SRSQYQGGGLVSEPGGDFQPSYYLPPPPPPLPPLPPLPPQPQFLPPGYLSALHFLPPPPP 300
SRSQYQGGGLVSEPGGDFQPSYYLPPPPPPLPPLPPLPPQPQFLPPGYLSALHFLPPPPP
Sbjct: 241 SRSQYQGGGLVSEPGGDFQPSYYLPPPPPPLPPLPPLPPQPQFLPPGYLSALHFLPPPPP 300
Query: 301 PPPPSSFSLTVLFDTDKENTDDQDAEVLSGEPSQPSSQEQSD 342
PPPPSSFSLTVLFDTDKENTDDQDAEVLSGEPSQPSSQEQSD
Sbjct: 301 PPPPSSFSLTVLFDTDKENTDDQDAEVLSGEPSQPSSQEQSD 342
>gi|154146231 DMRT-like family A2 [Homo sapiens]
Length = 542
Score = 99.8 bits (247), Expect = 3e-21
Identities = 56/121 (46%), Positives = 66/121 (54%), Gaps = 6/121 (4%)
Query: 2 ADKMVRTPKCSRCRNHGFLVPVKGHAGKCRWKQCLCEKCYLISERQKIMAAQKVLKTQAA 61
A+K RTPKC+RCRNHG + +KGH CRWK CLC KC LI+ERQ++MAAQ L+ Q A
Sbjct: 61 AEKYPRTPKCARCRNHGVVSALKGHKRYCRWKDCLCAKCTLIAERQRVMAAQVALRRQQA 120
Query: 62 EEEQEAALCAQGPKQASGAAAAA------PAPVPVPAASLRPLSPGTPSGDADPGPEGRA 115
+EE EA A G A AA P P S+ G P A G G A
Sbjct: 121 QEENEARELQLLYGTAEGLALAAANGIIPPRPAYEVFGSVCAADGGGPGAGAPAGTGGGA 180
Query: 116 A 116
A
Sbjct: 181 A 181
>gi|11056048 doublesex and mab-3 related transcription factor 3
[Homo sapiens]
Length = 472
Score = 90.5 bits (223), Expect = 2e-18
Identities = 64/165 (38%), Positives = 76/165 (46%), Gaps = 29/165 (17%)
Query: 7 RTPKCSRCRNHGFLVPVKGHAGKCRWKQCLCEKCYLISERQKIMAAQKVLKTQAAEEEQE 66
RTPKC+RCRNHG L +KGH CR+K C CEKC LI ERQ++MAAQ L+ Q A E E
Sbjct: 25 RTPKCARCRNHGVLSWLKGHKRYCRFKDCTCEKCILIIERQRVMAAQVALRRQQANESLE 84
Query: 67 AALCAQGPKQASGAAAAAPAPVPVPAASLRPLSPGTPSGDADPGPEGRAAACFFEQPPRG 126
+ + SLR L P GDA P+ A+ QP +
Sbjct: 85 SLI----------------------PDSLRALPGPPPPGDAVAAPQPPPAS----QPSQP 118
Query: 127 RNPGPRA-LQPVLGGRSHVEPSERAAVAMPSLAGPPFGAEAAGSG 170
+ P P A L R EP A A LA P E G G
Sbjct: 119 QPPRPAAELAAAAALRWTAEPQPGALQA--QLAKPDLTEERLGDG 161
>gi|170763515 DMRT-like family A1 [Homo sapiens]
Length = 504
Score = 88.6 bits (218), Expect = 7e-18
Identities = 46/98 (46%), Positives = 56/98 (57%), Gaps = 11/98 (11%)
Query: 7 RTPKCSRCRNHGFLVPVKGHAGKCRWKQCLCEKCYLISERQKIMAAQKVLKTQAAEEEQE 66
RTPKC+RCRNHG + +KGH CRW+ C C KC LI+ERQ++MAAQ L+ Q A+EE E
Sbjct: 93 RTPKCARCRNHGVVSALKGHKRFCRWRDCACAKCTLIAERQRVMAAQVALRRQQAQEESE 152
Query: 67 A-----ALCA------QGPKQASGAAAAAPAPVPVPAA 93
A LC+ G G A P PAA
Sbjct: 153 ARGLQRLLCSGLSWPPGGRASGGGGRAENPQSTGGPAA 190
>gi|62241026 doublesex and mab-3 related transcription factor 1
[Homo sapiens]
Length = 373
Score = 86.7 bits (213), Expect = 3e-17
Identities = 46/111 (41%), Positives = 60/111 (54%), Gaps = 20/111 (18%)
Query: 4 KMVRTPKCSRCRNHGFLVPVKGHAGKCRWKQCLCEKCYLISERQKIMAAQKVLKTQAAEE 63
K R PKC+RCRNHG+ P+KGH C W+ C C+KC LI+ERQ++MAAQ L+ Q A+E
Sbjct: 69 KSPRLPKCARCRNHGYASPLKGHKRFCMWRDCQCKKCNLIAERQRVMAAQVALRRQQAQE 128
Query: 64 EQ-----------EAALCAQGPK---------QASGAAAAAPAPVPVPAAS 94
E+ A L + + SG + PA VP AAS
Sbjct: 129 EELGISHPIPLPSAAELLVKRENNGSNPCLMTECSGTSQPPPASVPTTAAS 179
>gi|195947401 doublesex and mab-3 related transcription factor 2
isoform 1 [Homo sapiens]
Length = 226
Score = 80.5 bits (197), Expect = 2e-15
Identities = 33/63 (52%), Positives = 45/63 (71%)
Query: 4 KMVRTPKCSRCRNHGFLVPVKGHAGKCRWKQCLCEKCYLISERQKIMAAQKVLKTQAAEE 63
K+ RTPKC+RCRNHG + +KGH CRW+ C C C L+ ERQ++MAAQ L+ Q A E
Sbjct: 116 KLSRTPKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATE 175
Query: 64 EQE 66
+++
Sbjct: 176 DKK 178
>gi|5729806 doublesex and mab-3 related transcription factor 2
isoform 1 [Homo sapiens]
Length = 226
Score = 80.5 bits (197), Expect = 2e-15
Identities = 33/63 (52%), Positives = 45/63 (71%)
Query: 4 KMVRTPKCSRCRNHGFLVPVKGHAGKCRWKQCLCEKCYLISERQKIMAAQKVLKTQAAEE 63
K+ RTPKC+RCRNHG + +KGH CRW+ C C C L+ ERQ++MAAQ L+ Q A E
Sbjct: 116 KLSRTPKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATE 175
Query: 64 EQE 66
+++
Sbjct: 176 DKK 178
>gi|153945850 doublesex and mab-3 related transcription factor 2
isoform 2 [Homo sapiens]
Length = 561
Score = 80.5 bits (197), Expect = 2e-15
Identities = 33/63 (52%), Positives = 45/63 (71%)
Query: 4 KMVRTPKCSRCRNHGFLVPVKGHAGKCRWKQCLCEKCYLISERQKIMAAQKVLKTQAAEE 63
K+ RTPKC+RCRNHG + +KGH CRW+ C C C L+ ERQ++MAAQ L+ Q A E
Sbjct: 116 KLSRTPKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATE 175
Query: 64 EQE 66
+++
Sbjct: 176 DKK 178
>gi|94536830 DMRT-like family C2 [Homo sapiens]
Length = 367
Score = 73.6 bits (179), Expect = 2e-13
Identities = 91/318 (28%), Positives = 123/318 (38%), Gaps = 47/318 (14%)
Query: 7 RTPKCSRCRNHGFLVPVKGHAGKCRWKQCLCEKCYLISERQKIMAAQKVLKTQAAEEEQE 66
R+P C+RCRNHG +KGH C ++ C C KC LI ER+++MAAQ L+ Q E + +
Sbjct: 38 RSPTCARCRNHGVTAHLKGHKRLCLFQACECHKCVLILERRRVMAAQVALRRQ-QEAQLK 96
Query: 67 AALCAQG---PKQASGAAAAAPAP-VPVPAASLRPLSPGTPSGDA--DPGPEGR--AAAC 118
L +G PK + P VP ++ P P TP G P P G+
Sbjct: 97 KHLMRRGEASPKAPNHFRKGTTQPQVPSGKENIAP-QPQTPHGAVLLAPTPPGKNSCGPL 155
Query: 119 FFEQPPRGR-------NPGPRALQPVLGGRSHVEPSE--RAAVAMPSLAGPPFGAEAAGS 169
PP PGP L + P R P+++ PPF G+
Sbjct: 156 LLSHPPEASPLSWTPVPPGPWVPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPGT 215
Query: 170 GYPGPLDLRRPMRTVPG--PLFTDFVRPLNINPDRALGPEYPGGSSMHPYCPF-PLGYLD 226
L P T PG P+ T PL+ P GP P H P G D
Sbjct: 216 SL--QLPTHGPFTTCPGSHPVLT---APLSGEPQ---GP--PSQPRTHSTLILQPCGTPD 265
Query: 227 APPGVPLQQGFRHVSR----SQYQGGGLVSEPGGDFQPSYYLPPPPPPLPPLPPLPPQPQ 282
P G ++R S++Q +E + S P P +PP
Sbjct: 266 PLQLQPQASGASCLARTSGPSEWQLQQEAAEALVGLKDSSQAPRVTPSVPP--------- 316
Query: 283 FLPPGYLSALHFLPPPPP 300
P ++S LH PP P
Sbjct: 317 --NPAWISLLHPCGPPAP 332
Score = 29.6 bits (65), Expect = 4.1
Identities = 31/98 (31%), Positives = 39/98 (39%), Gaps = 7/98 (7%)
Query: 250 LVSEPGGDFQPSYYLPPPPPPLPPLPPLPPQPQFLPPGYLSALH-----FLPPPPPPPPP 304
L+S P + P + P PP P P LPP PP L+ LPP P P
Sbjct: 156 LLSHPP-EASPLSWTPVPPGPWVPGHWLPPGFSMPPPVVCRLLYQEPAVSLPPFPGFDPG 214
Query: 305 SSFSLTVLFD-TDKENTDDQDAEVLSGEPSQPSSQEQS 341
+S L T + LSGEP P SQ ++
Sbjct: 215 TSLQLPTHGPFTTCPGSHPVLTAPLSGEPQGPPSQPRT 252
>gi|119395760 diaphanous 1 isoform 2 [Homo sapiens]
Length = 1263
Score = 69.7 bits (169), Expect = 4e-12
Identities = 82/291 (28%), Positives = 108/291 (37%), Gaps = 71/291 (24%)
Query: 38 EKCYLISERQKIMAAQKVLKTQAAEEEQEAALCAQG-----PKQASGAAAAAPAPVPVPA 92
EK L SE+Q+I ++ L+ + ++ E A + + AS +AAA P VP+
Sbjct: 510 EKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPS 569
Query: 93 ASLRPLSPGTP--SGDADPGPEGRAAACFFEQPPRGRNPGPRALQPVLGGRSHVEPSERA 150
+ P +P P SG P P + PP P P P+ GG P
Sbjct: 570 RAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPP----PPPPPPPPLPGGVCISSP---- 621
Query: 151 AVAMPSLAG-------PPFGAEAAGSGYPGPLDLRRPMRTVPGPLFTDFVRPLNINPDRA 203
PSL G PP +A T+P P PL
Sbjct: 622 ----PSLPGGTAISPPPPLSGDA----------------TIPPP------PPLPEGVGIP 655
Query: 204 LGPEYPGGSSMHPYCPFPLGYLDAPPGVPLQQGFRHVSRSQYQGGGLVSEPGGDFQPSYY 263
PGG+++ P P P PP PL G + P
Sbjct: 656 SPSSLPGGTAIPPPPPLPGSARIPPPPPPL------------PGSAGIPPPPPPLPGEAG 703
Query: 264 LPPPPPPLPPLPPLPPQPQFLPPGYLSALHFLPPPP-----PPPPPSSFSL 309
+PPPPPPLP P +PP P F PG +PPPP PPPPP F +
Sbjct: 704 MPPPPPPLPGGPGIPPPPPF--PGGPG----IPPPPPGMGMPPPPPFGFGV 748
Score = 30.0 bits (66), Expect = 3.1
Identities = 37/146 (25%), Positives = 46/146 (31%), Gaps = 16/146 (10%)
Query: 71 AQGPKQASGAAAAAPAPVPVPAASLRPLSPGTPSGDADPGPEGRAAACFFEQPPRGRNPG 130
A P A P P P+P P P G A P P + PP PG
Sbjct: 629 AISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPL-PG 687
Query: 131 PRAL---QPVLGGRSHVEPSERAAVAMPSLAGPPFGAEAAGSGYPGPLDLRRPMRTVPGP 187
+ P L G + + P P + PP G G P P P +P P
Sbjct: 688 SAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPP--PFPGGPGIPPP----PPGMGMPPP 741
Query: 188 LFTDF------VRPLNINPDRALGPE 207
F V P + P + PE
Sbjct: 742 PPFGFGVPAAPVLPFGLTPKKLYKPE 767
>gi|119395758 diaphanous 1 isoform 1 [Homo sapiens]
Length = 1272
Score = 69.7 bits (169), Expect = 4e-12
Identities = 82/291 (28%), Positives = 108/291 (37%), Gaps = 71/291 (24%)
Query: 38 EKCYLISERQKIMAAQKVLKTQAAEEEQEAALCAQG-----PKQASGAAAAAPAPVPVPA 92
EK L SE+Q+I ++ L+ + ++ E A + + AS +AAA P VP+
Sbjct: 519 EKDALHSEKQQIATEKQDLEAEVSQLTGEVAKLTKELEDAKKEMASLSAAAITVPPSVPS 578
Query: 93 ASLRPLSPGTP--SGDADPGPEGRAAACFFEQPPRGRNPGPRALQPVLGGRSHVEPSERA 150
+ P +P P SG P P + PP P P P+ GG P
Sbjct: 579 RAPVPPAPPLPGDSGTIIPPPPAPGDSTTPPPPP----PPPPPPPPLPGGVCISSP---- 630
Query: 151 AVAMPSLAG-------PPFGAEAAGSGYPGPLDLRRPMRTVPGPLFTDFVRPLNINPDRA 203
PSL G PP +A T+P P PL
Sbjct: 631 ----PSLPGGTAISPPPPLSGDA----------------TIPPP------PPLPEGVGIP 664
Query: 204 LGPEYPGGSSMHPYCPFPLGYLDAPPGVPLQQGFRHVSRSQYQGGGLVSEPGGDFQPSYY 263
PGG+++ P P P PP PL G + P
Sbjct: 665 SPSSLPGGTAIPPPPPLPGSARIPPPPPPL------------PGSAGIPPPPPPLPGEAG 712
Query: 264 LPPPPPPLPPLPPLPPQPQFLPPGYLSALHFLPPPP-----PPPPPSSFSL 309
+PPPPPPLP P +PP P F PG +PPPP PPPPP F +
Sbjct: 713 MPPPPPPLPGGPGIPPPPPF--PGGPG----IPPPPPGMGMPPPPPFGFGV 757
Score = 30.0 bits (66), Expect = 3.1
Identities = 37/146 (25%), Positives = 46/146 (31%), Gaps = 16/146 (10%)
Query: 71 AQGPKQASGAAAAAPAPVPVPAASLRPLSPGTPSGDADPGPEGRAAACFFEQPPRGRNPG 130
A P A P P P+P P P G A P P + PP PG
Sbjct: 638 AISPPPPLSGDATIPPPPPLPEGVGIPSPSSLPGGTAIPPPPPLPGSARIPPPPPPL-PG 696
Query: 131 PRAL---QPVLGGRSHVEPSERAAVAMPSLAGPPFGAEAAGSGYPGPLDLRRPMRTVPGP 187
+ P L G + + P P + PP G G P P P +P P
Sbjct: 697 SAGIPPPPPPLPGEAGMPPPPPPLPGGPGIPPPP--PFPGGPGIPPP----PPGMGMPPP 750
Query: 188 LFTDF------VRPLNINPDRALGPE 207
F V P + P + PE
Sbjct: 751 PPFGFGVPAAPVLPFGLTPKKLYKPE 776
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 69.7 bits (169), Expect = 4e-12
Identities = 78/247 (31%), Positives = 91/247 (36%), Gaps = 32/247 (12%)
Query: 82 AAAPAPVPVPAASLRPLSPGTPSGDADPGPEGRAAACFFEQPPRGRNPGPR-ALQPVLGG 140
A P P P+P A + PL P +G P P AA PP PG L P L G
Sbjct: 918 AGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAI-----PPPPPLPGAGIPLPPPLPG 972
Query: 141 RSHVEPSERAAVAMPSL-----AGPPFGAEAAGSGYPGPLDLRRPMRTVPGPLFTDFVRP 195
P +P AG P G+G P P L P PL + P
Sbjct: 973 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1032
Query: 196 LNINPDRALGPEYP-GGSSMHPYCPFPLGYLDAPPGVPLQQGFRHVSRSQYQGGGLVSE- 253
P + P P G+ + P P P + PP +P G G G+
Sbjct: 1033 PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP---GAGIPPPPPLPGAGIPPPP 1089
Query: 254 --PGGDFQPSYYLP----PPPPPLP--PLPPLPPQP--QFLPPGYLSALHFLPPPP---- 299
PG P LP PPPPPLP +PP PP P PP L PPPP
Sbjct: 1090 PLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRV 1149
Query: 300 --PPPPP 304
PPPPP
Sbjct: 1150 GIPPPPP 1156
Score = 63.2 bits (152), Expect = 3e-10
Identities = 73/245 (29%), Positives = 87/245 (35%), Gaps = 35/245 (14%)
Query: 81 AAAAPAPVPVPAASLRPLSPGTPSGDADPGPEGRAAACFFEQPPRGRNPGPRALQPVLGG 140
+ A P P P+ + P P G P P A PP PG P
Sbjct: 893 STAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPL---PGAGIPPP---- 945
Query: 141 RSHVEPSERAAVAMPSL---AGPPFGAEAAGSGYPGPLDLRRPMRTVPGPLFTDFVRPLN 197
P AA+ P AG P G+G P P L P PL + P
Sbjct: 946 ----PPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1001
Query: 198 INPDRALGPEYP-GGSSMHPYCPFPLGYLDAPPGVPLQQGFRHVSRSQYQGGGLVSE--- 253
P + P P G+ + P P P + PP +P G G G+
Sbjct: 1002 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP---GAGIPPPPPLPGAGIPPPPPL 1058
Query: 254 PGGDFQPSYYLP----PPPPPLP--PLPPLPPQP--QFLPPGYLSALHFLPPPP------ 299
PG P LP PPPPPLP +PP PP P PP L + PPPP
Sbjct: 1059 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGI 1118
Query: 300 PPPPP 304
PPPPP
Sbjct: 1119 PPPPP 1123
Score = 62.4 bits (150), Expect = 6e-10
Identities = 76/254 (29%), Positives = 87/254 (34%), Gaps = 32/254 (12%)
Query: 74 PKQASGAAAAAPAPVPVPAASLRPLSPGTPSGDADPGPEGRAAACFFEQPPRGRNPGPRA 133
P GAA P P+P PL P P P P A P G P
Sbjct: 945 PPPLPGAAIPPPPPLPGAGI---PLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP-- 999
Query: 134 LQPVLGGRSHVEPSERAAVAMPSL-----AGPPFGAEAAGSGYPGPLDLRRPMRTVPGPL 188
P L G P +P AG P G+G P P L P PL
Sbjct: 1000 -PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1058
Query: 189 FTDFVRPLNINPDRALGPEYP-GGSSMHPYCPFPLGYLDAPPGVPLQQGFRHVSRSQYQG 247
+ P P + P P G+ + P P P + PP +P G G
Sbjct: 1059 PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP---GVGIPPPPPLPG 1115
Query: 248 GGLVSE---PGGDFQPSYYLP----PPPPPLP--PLPPLPPQP--QFLPPGYLSALHFLP 296
G+ PG P LP PPPPPLP +PP PP P PP L P
Sbjct: 1116 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPP 1175
Query: 297 PPP------PPPPP 304
PPP PPPPP
Sbjct: 1176 PPPLPGVGIPPPPP 1189
Score = 59.3 bits (142), Expect = 5e-09
Identities = 71/241 (29%), Positives = 85/241 (35%), Gaps = 37/241 (15%)
Query: 82 AAAPAPVPVPAASLRPLSPGTPSGDADPGPEGRAAACFFEQPPRGRNPGPRALQPV-LGG 140
A P P P+P A + P P +G P P A PP PG P L G
Sbjct: 1006 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI-----PPPPPLPGAGIPPPPPLPG 1060
Query: 141 RSHVEPSERAAVAMPSL-----AGPPFGAEAAGSGYPGPLDLRRPMRTVPGPLFTDFVRP 195
P +P AG P G+G P P L P PL + P
Sbjct: 1061 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPP 1120
Query: 196 LNINPDRALGPEYP-GGSSMHPYCPFPLGYLDAPPGVPLQQGFRHVSRSQYQGGGLVSEP 254
P + P P G+ + P P P + PP +P G G+ P
Sbjct: 1121 PPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLP--------------GAGIPPPP 1166
Query: 255 ---GGDFQPSYYLP----PPPPPLPP--LPPLPPQPQ--FLPPGYLSALHFLPPPPPPPP 303
G P LP PPPPPLP +PP PP P PP L + P P PP P
Sbjct: 1167 PLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLP 1226
Query: 304 P 304
P
Sbjct: 1227 P 1227
Score = 54.3 bits (129), Expect = 2e-07
Identities = 74/248 (29%), Positives = 86/248 (34%), Gaps = 50/248 (20%)
Query: 82 AAAPAPVPVPAASLRPLSPGTPSGDADPGPEGRAAACFFEQPPRGRNPGPRALQPV-LGG 140
A P P P+P A + P P +G P P A PP PG P L G
Sbjct: 1039 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGI-----PPPPPLPGAGIPPPPPLPG 1093
Query: 141 RSHVEPSERAAVAMPSL-----AGPPFGAEAAGSGYPGPLDLRRPMRTVPGPLFTDFVRP 195
P V +P AG P G+G P P L P PL + P
Sbjct: 1094 AGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPP 1153
Query: 196 LNINPDRALGPEYP-GGSSMHPYCPFPLGYLDAPPGVPLQQGFRHVSRSQYQGGGLVSEP 254
P + P P G+ + P P PL + PP PL P
Sbjct: 1154 PPPLPGAGIPPPPPLPGAGIPP--PPPLPGVGIPPPPPL--------------------P 1191
Query: 255 GGDFQPSYYLP----PPPPPLP-------PLPPLPPQPQFLPPGYLSALHFLPPPPPPPP 303
G P LP PPPPPLP P PPLPP +PP L LP PP
Sbjct: 1192 GVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPL-----LPVSGPPLL 1246
Query: 304 PSSFSLTV 311
P S T+
Sbjct: 1247 PQVGSSTL 1254
Score = 46.2 bits (108), Expect = 4e-05
Identities = 48/155 (30%), Positives = 56/155 (36%), Gaps = 21/155 (13%)
Query: 160 PPFGAEAAGSGYPGPLDLRRPMRTVPGPLFTDFVRPLNINPDRALGPEYP-GGSSMHPYC 218
PP + S PG + P +PG P A+ P G+ M P
Sbjct: 859 PPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTL-------PSTAIPQPPPLQGTEMLPPP 911
Query: 219 PFPLGYLDAPPGVPLQQGFRHVSRSQYQGGGLVSEPGGDFQPSYYLPPPPP---PLPPLP 275
P PL PP PL G + G G+ P P +PPPPP PLP
Sbjct: 912 PPPLPGAGIPPPPPLP-GAGILPLPPLPGAGIPPPPP---LPGAAIPPPPPLPGAGIPLP 967
Query: 276 PLPPQPQFLPPGYLSALHFLPPPP------PPPPP 304
P P PP L PPPP PPPPP
Sbjct: 968 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1002
Score = 45.4 bits (106), Expect = 7e-05
Identities = 39/115 (33%), Positives = 49/115 (42%), Gaps = 34/115 (29%)
Query: 195 PLNINPDRALGPEYPGGSSMHPYCPFPLGYLDAPPGVPLQQGFRHVSRSQYQGGGLVSEP 254
P +I+ + E+ S+ C P +PP +P + S S G G+V
Sbjct: 830 PHSISTEFQTSHEHSVSSAFKNSCNIP-----SPPPLPCTE-----SSSSMPGLGMV--- 876
Query: 255 GGDFQPSYYLPPPPPPLPPL--PPLP----PQPQFLPPGYLSALHFLPPPPPPPP 303
PPPPPPLP + P LP PQP PP L LPPPPPP P
Sbjct: 877 ----------PPPPPPLPGMTVPTLPSTAIPQP---PP--LQGTEMLPPPPPPLP 916
Score = 32.0 bits (71), Expect = 0.82
Identities = 43/150 (28%), Positives = 56/150 (37%), Gaps = 27/150 (18%)
Query: 45 ERQKIMAAQKVLKTQAAEEEQEAALCAQGPKQASGAAAAAPA-PVPVPAASLRPLSPGTP 103
+ ++ ++A L A E +E Q P + AP+ P PAA P S P
Sbjct: 268 DTEQALSALSDLPESLAAEPREPQ---QPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFP 324
Query: 104 SGDADPGPEGRAAAC-------------FFEQPPRGRNPGPRALQPVLG----GRSHVEP 146
+A PG E A FE PRG +PG P +G R EP
Sbjct: 325 FPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRG-SPG-EEWAPEVGEDAPQRLGEEP 382
Query: 147 SERA----AVAMPSLAGPPFGAEAAGSGYP 172
E A A A SL G P ++ YP
Sbjct: 383 EEEAQGPDAPAAASLPGSPAPSQRCFKPYP 412
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 65.5 bits (158), Expect = 7e-11
Identities = 97/349 (27%), Positives = 121/349 (34%), Gaps = 76/349 (21%)
Query: 48 KIMAAQKVLKTQAAEEEQEAALCAQGPKQASGAAAAAPAPVPVPAASLRPLSPGTPSGDA 107
+I A + V + +A E + +AL A + SG P+ PA + R + GT G
Sbjct: 126 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPS----PAMARRSRAAGTEVGLP 181
Query: 108 DPGPEGRAAACFFEQPPRGRNPGPRALQPVLGGRSHVEPSERAAVAMPSLAG---PPFGA 164
P P R PR GPR S EPS AA PS G P
Sbjct: 182 RPAPSAR---------PRPPTEGPRKSVSSASEHSTTEPSP-AARRRPSAGGGLQRPASR 231
Query: 165 EAAGSGYP-------GPLDLRRPMR----TVPGPLFTDFVRPLNINPDR-----ALGP-- 206
+ S P GP P + P P +RP + P R ALGP
Sbjct: 232 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 291
Query: 207 ----EYPGGSS-MHPYCPFPLGYLDAPPGVPLQQGFRHVSRSQYQGGGLVSEPGGDFQPS 261
P S+ P P L L +PP P Q + G + F PS
Sbjct: 292 SSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSL-------GSPTLQATHSFLPS 344
Query: 262 YYLPP---PPPPLPP---LPPL--PPQPQFLPP----------------GYLSALHFLPP 297
L P PPP PP LPPL PP P PP +L F PP
Sbjct: 345 PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 404
Query: 298 PPPP-----PPPSSFSLTVLFDTDKENTDDQDAEVLSGEPSQPSSQEQS 341
P PP PP+S ++ + A L PS P+S S
Sbjct: 405 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 453
Score = 57.4 bits (137), Expect = 2e-08
Identities = 66/290 (22%), Positives = 97/290 (33%), Gaps = 36/290 (12%)
Query: 46 RQKIMAAQKVLKTQ---AAEEEQEAALCAQGPKQASGAAAAAPAPVPVPAASLRPLSPGT 102
R+ + +A + T+ AA A Q P S +++A P P + +P
Sbjct: 197 RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA 256
Query: 103 PSGDADPGPEGRAAACFFEQPPRGRNP--------GPRALQPVLGGRSHVEPSERAAVAM 154
P+ + P P+G A +PP+ P GP + P+ PS A ++
Sbjct: 257 PAHPSQPKPKGLQAL----RPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSL 312
Query: 155 PSLAGPPFGAEAAGSGYPGPLDLRRPMRTVPGPLFTDFVRP------------LNINPDR 202
+L PP + + G L+ +P P + P L P
Sbjct: 313 QTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP 372
Query: 203 ALGPEYPGGSSMHPYCPFPLGY------LDAPPGVPLQQGFRHVSRSQYQGGGLVSE--P 254
P ++ P P L PP P+Q F + P
Sbjct: 373 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 432
Query: 255 GGDFQPSYYLPPPPPPLPPL-PPLPPQPQFLPPGYLSALHFLPPPPPPPP 303
P +PP PP PP+ P P PQ PP L PPP PP
Sbjct: 433 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP 482
Score = 52.4 bits (124), Expect = 6e-07
Identities = 72/263 (27%), Positives = 82/263 (31%), Gaps = 56/263 (21%)
Query: 71 AQGPKQASGAAAAAPAPVPVPAASLRPLSP-GTPSGDADPGPEGRAAACFFEQPPRGRNP 129
A P QA A A P P + PLSP TPS A A A Q P P
Sbjct: 351 ATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP-----NALAVHLLQAPFSPPP 405
Query: 130 GPRALQPVLGGRSH-VEPSERA-AVAMPSLAGPPFGAEAAGSGYPG-------------- 173
P P S V PS + A PSLA PP + P
Sbjct: 406 SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 465
Query: 174 ----PLDLRRPMRTVPGPLFTDFVRPLNINPDRALGPEYPGGSSMHPYCPFPLGYLDAPP 229
PL L +P P L T ++ L P +PG + P P+ L PP
Sbjct: 466 LAAPPLQLAKPPPQAPPALATPPLQALPSPP-----ASFPGQAPFSPSASLPMSPLATPP 520
Query: 230 GVPLQQGFRHVSRSQYQGGGLVSEPGGDFQPSYYLPPPPPPLP----PLPPLPPQPQFLP 285
P P +PP PP P P P P P
Sbjct: 521 P---------------------QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV 559
Query: 286 PGYLSALHFLPPPPPPPPPSSFS 308
G L P PPPPP S S
Sbjct: 560 SGPRLTLALAPGPPPPPSRSPSS 582
Score = 46.2 bits (108), Expect = 4e-05
Identities = 70/282 (24%), Positives = 98/282 (34%), Gaps = 40/282 (14%)
Query: 54 KVLKTQAAEEEQEAALCAQGPKQASGAAAAAPAPVPVPAA--SLR--PLSPGTPSGDADP 109
+ L+ ++ A A GP +S A +P+ P P+A SL+ P P TP A
Sbjct: 269 QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATT 328
Query: 110 G---PEGRAAACFFEQPPRG--RNPGPRALQPVLGGRSHVEPSERAAVAMPSLAGPPFGA 164
P +A F PP P P+A + PS A+ + LA P A
Sbjct: 329 SLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQA 388
Query: 165 ---------EAAGSGYPGPLDLRRPMRTVPGPLFTDFVRPLNINPDRALGPEY---PGGS 212
+A S P P ++ P P + P + P P P
Sbjct: 389 PNALAVHLLQAPFSPPPSP-PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 447
Query: 213 SMHPYCPFPLGYLDAPPGVPLQQGFRHVSRSQYQGGGLVSEPGGDFQPSYYLPPPPPPLP 272
+ P P APP PL +++ Q ++ P P LP PP P
Sbjct: 448 ASPPMSPSATPPPQAPP--PLAAPPLQLAKPPPQAPPALATP-----PLQALPSPPASFP 500
Query: 273 -----------PLPPLPPQPQFLPPGYLSALHFLPPPPPPPP 303
P+ PL P PP + L +PP PP P
Sbjct: 501 GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP 542
Score = 44.3 bits (103), Expect = 2e-04
Identities = 83/331 (25%), Positives = 103/331 (31%), Gaps = 68/331 (20%)
Query: 73 GPKQASGAAAAAPAPVPVPAASLRP---LSPGTPSGDADPGPEGR-----------AAAC 118
GP + S A+ PA + P SPG SG PGP G+ A
Sbjct: 78 GPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGK 137
Query: 119 FFEQPPRG----------RNPGPRALQPVLGGRSHVEPSE-------RAAVAMPSLAGPP 161
E P R P P P + RS +E +A P GP
Sbjct: 138 ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPR 197
Query: 162 FGAEAA---GSGYPGPLDLRRPMRTVPGPLFTDFVRPLNINPDRALGPEYPGGSS----- 213
+A + P P RRP + G L R L+ + P G S+
Sbjct: 198 KSVSSASEHSTTEPSPAARRRP--SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 255
Query: 214 --MHPYCPFPLGYLD------APPGVPLQQGFRHVSRSQYQGGGLVSEPGGDFQPSYYLP 265
HP P P G PP +S S + P PS
Sbjct: 256 APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTL 315
Query: 266 PPPPPLPP--------LPPLPPQPQFLPPGYLSALHFLPP--PP---------PPPPPSS 306
P PP PP P L FLP LS L PP PP PP PP+S
Sbjct: 316 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS 375
Query: 307 FSLTVLFDTDKENTDDQDAEVLSGEPSQPSS 337
L+ L + + +L S P S
Sbjct: 376 PPLSPLATPSPQAPNALAVHLLQAPFSPPPS 406
Score = 28.9 bits (63), Expect = 7.0
Identities = 27/104 (25%), Positives = 30/104 (28%), Gaps = 6/104 (5%)
Query: 72 QGPKQASGAAAAAPAPVPVPAASLRPLSPGTPSGDAD-PGPEGRAAACFFEQPPRGRNPG 130
Q P + P P P P TP D GP A PP R+P
Sbjct: 522 QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS 581
Query: 131 PRALQPVLGGRSHVEPSERAAVAMPSLAGPPFGAEAAGSGYPGP 174
P L G S A L G G E + P P
Sbjct: 582 STLSGPDLAGH-----SSSATSTPEELRGYDSGPEGGAAASPPP 620
>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
subunit [Homo sapiens]
Length = 551
Score = 63.2 bits (152), Expect = 3e-10
Identities = 73/251 (29%), Positives = 90/251 (35%), Gaps = 47/251 (18%)
Query: 94 SLRPLSPGTPSGDADPGPEGRAAACFFEQPPRGRNPGPRALQPVLGGRSHVEPSERAAVA 153
S + G SG+ GP G ++ F Q RGR P A V GG P+
Sbjct: 171 SRKTTQSGQMSGEGKAGPPGGSSRAAFPQGGRGRGRFPGA---VPGGDRFPGPAGPGGPP 227
Query: 154 MPSLAG-----PPFGAEAAGSGYPGPLDLRRPMRTVPGPLFTDFVRPLNINPDRALGPEY 208
P AG PP G G PGP P + +P PL P+R P
Sbjct: 228 PPFPAGQTPPRPPLGPP----GPPGPPGPPPPGQVLPPPLAGP--------PNRGDRPPP 275
Query: 209 PGGSSMHPYCPFPLGYLDAPPGVPLQQGFRHVSRSQYQGGGLVSEPGGDFQPSYYLPPP- 267
P P+ PLG L PPG P P + P PPP
Sbjct: 276 PVLFPGQPFGQPPLGPL--PPGPP--------------------PPVPGYGPPPGPPPPQ 313
Query: 268 ---PPPLPPLPPLPPQPQFLPPGYLSALHFLPPPPPPPPPSSFSLTVLFDTDKENTDDQD 324
PPP P PP PP P PP L+ LP PPP PP + + F N+
Sbjct: 314 QGPPPPPGPFPPRPPGP-LGPPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPPTNSGMPT 372
Query: 325 AEVLSGEPSQP 335
++ P+ P
Sbjct: 373 SDSRGPPPTDP 383
Score = 49.3 bits (116), Expect = 5e-06
Identities = 68/243 (27%), Positives = 73/243 (30%), Gaps = 77/243 (31%)
Query: 73 GPKQASGAAAAAPAPVPVPAASL---RPLSPGTPSGDADPGPEGRAAACFFEQPP-RGRN 128
G + G A P P PA PL P P G P P G+ PP RG
Sbjct: 213 GGDRFPGPAGPGGPPPPFPAGQTPPRPPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRGDR 272
Query: 129 PGPRALQPVLGGRSHVEPSERAAVAMPSLAGPPFGAEAAGSGYPGPLDLRRPMRTVPGPL 188
P P L P G PFG G PGP PGP
Sbjct: 273 PPPPVLFP----------------------GQPFGQPPLGPLPPGPPPPVPGYGPPPGP- 309
Query: 189 FTDFVRPLNINPDRALGPEYPGGSSMHPYCPFPLGYLDAPPGVPLQQGFRHVSRSQYQGG 248
P GP P G P+ P P G P G PL
Sbjct: 310 -----------PPPQQGPPPPPG----PFPPRPPG----PLGPPL--------------- 335
Query: 249 GLVSEPGGDFQPSYYLPPPPPPLPPLPPLPPQPQFLPPGYLSALHFL----PPPPPP--- 301
P +LP PPP PP P P F PP S + PPP P
Sbjct: 336 --------TLAPPPHLPGPPPGAPP-PAPHVNPAFFPPPTNSGMPTSDSRGPPPTDPYGR 386
Query: 302 PPP 304
PPP
Sbjct: 387 PPP 389
>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
Length = 1003
Score = 60.5 bits (145), Expect = 2e-09
Identities = 81/274 (29%), Positives = 105/274 (38%), Gaps = 59/274 (21%)
Query: 72 QGPKQASGAAAAAPAPVPVPAASLRPLSPGTPS-----GDADPGPEGRAAA-------CF 119
+GP+ + APAPVP P + P P PS G PGP +
Sbjct: 379 RGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAH 438
Query: 120 FEQPPR---GRNPGPR-ALQPVLGGRSHVE-------PSERAAVAMPSLAGPPFGAEAAG 168
PP G P PR +QP L G + P+ AA P + P + + G
Sbjct: 439 LPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEG 498
Query: 169 SGY-PGPLDLRRPM---RTVPGPLFTDFVRPLNINPDRALGPEYPGGSSMHPYCPFPLGY 224
G GP P+ P P +P++ L G M P PL
Sbjct: 499 LGMGAGPACPLPPLAGGEAFPFP-----------SPEQGLALSGAGFPGMLGALPLPLS- 546
Query: 225 LDAPPGVPLQQGFRHVSRSQYQGGGLVSEPGGDFQPSYYLPPPPPPLPPLPPLPPQPQFL 284
L PP PL ++ S + G+++ GG P LPPP P PPL P P+
Sbjct: 547 LGQPPPSPL------LNHSLF---GVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPE---- 593
Query: 285 PPGYLSALHFLPPPP----PPP--PPSSFSLTVL 312
P L A LPPPP PPP PPS+ + L
Sbjct: 594 GPSLLVA-SLLPPPPSDLLPPPSAPPSNLLASFL 626
Score = 40.8 bits (94), Expect = 0.002
Identities = 67/248 (27%), Positives = 81/248 (32%), Gaps = 44/248 (17%)
Query: 69 LCAQGPKQASGAAAAAPAPVPVPAASLRPLSPGTPSGDADPGPEGRAAACFFEQPPRGRN 128
L A GP G +A A G PSG+ G + F PP
Sbjct: 628 LLALGPTAGDGEGSAEGA--------------GGPSGEPFSGLGDLSPLLF---PPLSAP 670
Query: 129 PGPRALQPVLGGRSHVEPS---ERAAVAMPSLAGPPFGAEAAGSGYPGPLDLRRPMRTVP 185
P AL L + PS + V GPP + + PG L +
Sbjct: 671 PTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDPGASSLGKAPSNSG 730
Query: 186 GPLFTDFVRPLNINPDRALGPEYPGGSSMHPYCPFPLGYLDAPPGVPLQQGFRHVSRSQY 245
P P ++P LG G S P L L PPG PL G +
Sbjct: 731 RP-------PQLLSP--LLGASLLGDLSSLTSSPGALPSLLQPPG-PLLSG--QLGLQLL 778
Query: 246 QGGGL------VSEPGGDFQPSYYLPPPPPPLPPLPP------LPPQPQFLPPGYLSALH 293
GGG S P S +PP P P LPP L P+P P L+ H
Sbjct: 779 PGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPH 838
Query: 294 FLPPPPPP 301
P PP P
Sbjct: 839 GSPDPPVP 846
Score = 37.0 bits (84), Expect = 0.026
Identities = 72/279 (25%), Positives = 86/279 (30%), Gaps = 69/279 (24%)
Query: 87 PVPVPAA-SLRPLSPGTPSGDADPGP---EGRAAACFFEQPPRGRNPGPRALQPVLGGRS 142
P+ VP + PL+P TP G A GP E C + R+++ S
Sbjct: 67 PLNVPKVFNFDPLAPVTPGG-AGVGPASEEDMTKLCNHRRKAVAMATLYRSMETTC---S 122
Query: 143 HVEPSERAAVAM-------PSLAGPPFGAEAAG--SGYPGPLDLRRPMRTVPGPLFTDFV 193
H P E A+ M P A PP +G PG L P + F
Sbjct: 123 HSSPGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVS---QAFPTLA 179
Query: 194 RPLNINPDRALGPEYPGGSSMHPYCPFPLGYLDAPPGVPL------QQGFRHVSRSQYQG 247
P + P R P GGSS + P APP P + RS
Sbjct: 180 GPGGLFPPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVP 239
Query: 248 GGLVSEPGGDFQPSYYLPPP---------PPPLPPL------------PPL--------- 277
L S P S PP PPPLPP PP+
Sbjct: 240 SDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPL 299
Query: 278 -------------PPQPQFLPPGYLSALHFLPPPPPPPP 303
P P FL LSA PP PPP
Sbjct: 300 VLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPP 338
Score = 34.3 bits (77), Expect = 0.17
Identities = 66/265 (24%), Positives = 83/265 (31%), Gaps = 56/265 (21%)
Query: 71 AQGPKQASGAAAAAPAPVPVPAASLRPLS------------------PGTPSGDADPGPE 112
+ P+ A +PAP P PA SL S P P + P +
Sbjct: 198 SSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSD 257
Query: 113 GRAAACFFEQ-----PPRGR---NPGPRALQPVLGGRSHVEPSERAAVAMPSLAGPPFGA 164
C PP +PGP + PV H+ P++ GP
Sbjct: 258 PPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPP 317
Query: 165 EAAGSGYPGPLDLRRPMRTVPGPLFTDFVRPLNINPDRALGPEYPGGSSMHPYCPFPLGY 224
A S + P +P P RP RA P SS+ P P
Sbjct: 318 FLASSLLSAAAKAQHP--PLPPPSTLQGRRP------RAQAPSASHSSSLRPSQRRPR-- 367
Query: 225 LDAPPGVPLQQGFRHVSRSQYQGGGLVSEPGGDFQPSYYLPPPPPPLPPLPPLPPQPQFL 284
PP V FR + E G P P P P+P LP Q +
Sbjct: 368 --RPPTV-----FR------------LLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPI 408
Query: 285 PPGYLSALHFLPPPPPPPPPSSFSL 309
P LS L LP P P SF+L
Sbjct: 409 LPSVLSLLG-LPTPGPSHSDGSFNL 432
>gi|239757043 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 996
Score = 58.9 bits (141), Expect = 6e-09
Identities = 71/242 (29%), Positives = 89/242 (36%), Gaps = 47/242 (19%)
Query: 65 QEAALCAQGPKQASGAAAAAPAPVPVPAASLRPLSPGTPSGDADPGPEGRAAACFFEQPP 124
++A L P A+G+A AAP P P ++ G SG P + FE PP
Sbjct: 507 RQAFLDLAEPGGAAGSAEAAPPPGQPPQV----VANGPGSGPPPPAGGAGSRDALFESPP 562
Query: 125 RGRNPGPRALQPVLGGRSHVEPSERAAVAMPSLAGPPFGAEAAGSGYPGPLDLRRPMRTV 184
G GG + S + S+A GA AAGSG G V
Sbjct: 563 GGS-----------GG----DCSAGSTPPADSVAAAGAGAAAAGSGPAG--------SRV 599
Query: 185 PGPLFTDFVRPLNINPDRALGPEYPGGSSMHPYCPFPLGYLDAPPGVPLQQGFRHVSRSQ 244
P P +P G + GGS H P+G D + G +
Sbjct: 600 PAP----------HHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHS 649
Query: 245 YQGGGLVSEPGGDFQPSYYLPPPPPPLPPLP--PLPPQPQFLPPGYLSALHFLPPPPPPP 302
Q + P P ++ PP PP P LPPQP PG H PPPPPPP
Sbjct: 650 AQ-----THPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPD--EPG-SERHHPAPPPPPPP 701
Query: 303 PP 304
PP
Sbjct: 702 PP 703
Score = 31.6 bits (70), Expect = 1.1
Identities = 25/85 (29%), Positives = 30/85 (35%), Gaps = 23/85 (27%)
Query: 254 PGGDFQPSYYLPPPPPPLPPLPPLPPQPQFL---------PPGYLSALHFLPPP------ 298
PGG P+Y PPP PP L P L P G + PPP
Sbjct: 476 PGGLPVPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQV 535
Query: 299 --------PPPPPPSSFSLTVLFDT 315
PPPP + S LF++
Sbjct: 536 VANGPGSGPPPPAGGAGSRDALFES 560
Score = 29.3 bits (64), Expect = 5.3
Identities = 13/20 (65%), Positives = 13/20 (65%), Gaps = 2/20 (10%)
Query: 287 GYLSALHFL--PPPPPPPPP 304
G L H L PPPPPPPPP
Sbjct: 274 GGLLGPHLLGAPPPPPPPPP 293
Score = 28.9 bits (63), Expect = 7.0
Identities = 9/9 (100%), Positives = 9/9 (100%)
Query: 296 PPPPPPPPP 304
PPPPPPPPP
Sbjct: 286 PPPPPPPPP 294
Score = 28.9 bits (63), Expect = 7.0
Identities = 16/35 (45%), Positives = 18/35 (51%), Gaps = 11/35 (31%)
Query: 246 QGGGLVSEPGGDFQPSYYLPPPPPPLPPLPPLPPQ 280
Q G + +PG D LPPPPP PPL PQ
Sbjct: 821 QEDGKLGDPGSD------LPPPPP-----PPLAPQ 844
Score = 28.5 bits (62), Expect = 9.1
Identities = 12/23 (52%), Positives = 13/23 (56%)
Query: 255 GGDFQPSYYLPPPPPPLPPLPPL 277
GG + L PPPP PP PPL
Sbjct: 273 GGGLLGPHLLGAPPPPPPPPPPL 295
Score = 28.5 bits (62), Expect = 9.1
Identities = 11/17 (64%), Positives = 11/17 (64%)
Query: 265 PPPPPPLPPLPPLPPQP 281
PPPPPP PPL L P
Sbjct: 286 PPPPPPPPPLAELAGAP 302
>gi|239751555 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 58.9 bits (141), Expect = 6e-09
Identities = 71/242 (29%), Positives = 89/242 (36%), Gaps = 47/242 (19%)
Query: 65 QEAALCAQGPKQASGAAAAAPAPVPVPAASLRPLSPGTPSGDADPGPEGRAAACFFEQPP 124
++A L P A+G+A AAP P P ++ G SG P + FE PP
Sbjct: 507 RQAFLDLAEPGGAAGSAEAAPPPGQPPQV----VANGPGSGPPPPAGGAGSRDALFESPP 562
Query: 125 RGRNPGPRALQPVLGGRSHVEPSERAAVAMPSLAGPPFGAEAAGSGYPGPLDLRRPMRTV 184
G GG + S + S+A GA AAGSG G V
Sbjct: 563 GGS-----------GG----DCSAGSTPPADSVAAAGAGAAAAGSGPAG--------SRV 599
Query: 185 PGPLFTDFVRPLNINPDRALGPEYPGGSSMHPYCPFPLGYLDAPPGVPLQQGFRHVSRSQ 244
P P +P G + GGS H P+G D + G +
Sbjct: 600 PAP----------HHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHS 649
Query: 245 YQGGGLVSEPGGDFQPSYYLPPPPPPLPPLP--PLPPQPQFLPPGYLSALHFLPPPPPPP 302
Q + P P ++ PP PP P LPPQP PG H PPPPPPP
Sbjct: 650 AQ-----THPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPD--EPG-SERHHPAPPPPPPP 701
Query: 303 PP 304
PP
Sbjct: 702 PP 703
Score = 31.6 bits (70), Expect = 1.1
Identities = 25/85 (29%), Positives = 30/85 (35%), Gaps = 23/85 (27%)
Query: 254 PGGDFQPSYYLPPPPPPLPPLPPLPPQPQFL---------PPGYLSALHFLPPP------ 298
PGG P+Y PPP PP L P L P G + PPP
Sbjct: 476 PGGLPVPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQV 535
Query: 299 --------PPPPPPSSFSLTVLFDT 315
PPPP + S LF++
Sbjct: 536 VANGPGSGPPPPAGGAGSRDALFES 560
Score = 29.3 bits (64), Expect = 5.3
Identities = 13/20 (65%), Positives = 13/20 (65%), Gaps = 2/20 (10%)
Query: 287 GYLSALHFL--PPPPPPPPP 304
G L H L PPPPPPPPP
Sbjct: 274 GGLLGPHLLGAPPPPPPPPP 293
Score = 28.9 bits (63), Expect = 7.0
Identities = 9/9 (100%), Positives = 9/9 (100%)
Query: 296 PPPPPPPPP 304
PPPPPPPPP
Sbjct: 286 PPPPPPPPP 294
Score = 28.9 bits (63), Expect = 7.0
Identities = 16/35 (45%), Positives = 18/35 (51%), Gaps = 11/35 (31%)
Query: 246 QGGGLVSEPGGDFQPSYYLPPPPPPLPPLPPLPPQ 280
Q G + +PG D LPPPPP PPL PQ
Sbjct: 821 QEDGKLGDPGSD------LPPPPP-----PPLAPQ 844
Score = 28.5 bits (62), Expect = 9.1
Identities = 12/23 (52%), Positives = 13/23 (56%)
Query: 255 GGDFQPSYYLPPPPPPLPPLPPL 277
GG + L PPPP PP PPL
Sbjct: 273 GGGLLGPHLLGAPPPPPPPPPPL 295
Score = 28.5 bits (62), Expect = 9.1
Identities = 11/17 (64%), Positives = 11/17 (64%)
Query: 265 PPPPPPLPPLPPLPPQP 281
PPPPPP PPL L P
Sbjct: 286 PPPPPPPPPLAELAGAP 302
>gi|239746067 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 58.9 bits (141), Expect = 6e-09
Identities = 71/242 (29%), Positives = 89/242 (36%), Gaps = 47/242 (19%)
Query: 65 QEAALCAQGPKQASGAAAAAPAPVPVPAASLRPLSPGTPSGDADPGPEGRAAACFFEQPP 124
++A L P A+G+A AAP P P ++ G SG P + FE PP
Sbjct: 507 RQAFLDLAEPGGAAGSAEAAPPPGQPPQV----VANGPGSGPPPPAGGAGSRDALFESPP 562
Query: 125 RGRNPGPRALQPVLGGRSHVEPSERAAVAMPSLAGPPFGAEAAGSGYPGPLDLRRPMRTV 184
G GG + S + S+A GA AAGSG G V
Sbjct: 563 GGS-----------GG----DCSAGSTPPADSVAAAGAGAAAAGSGPAG--------SRV 599
Query: 185 PGPLFTDFVRPLNINPDRALGPEYPGGSSMHPYCPFPLGYLDAPPGVPLQQGFRHVSRSQ 244
P P +P G + GGS H P+G D + G +
Sbjct: 600 PAP----------HHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHS 649
Query: 245 YQGGGLVSEPGGDFQPSYYLPPPPPPLPPLP--PLPPQPQFLPPGYLSALHFLPPPPPPP 302
Q + P P ++ PP PP P LPPQP PG H PPPPPPP
Sbjct: 650 AQ-----THPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPD--EPG-SERHHPAPPPPPPP 701
Query: 303 PP 304
PP
Sbjct: 702 PP 703
Score = 31.6 bits (70), Expect = 1.1
Identities = 25/85 (29%), Positives = 30/85 (35%), Gaps = 23/85 (27%)
Query: 254 PGGDFQPSYYLPPPPPPLPPLPPLPPQPQFL---------PPGYLSALHFLPPP------ 298
PGG P+Y PPP PP L P L P G + PPP
Sbjct: 476 PGGLPVPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQV 535
Query: 299 --------PPPPPPSSFSLTVLFDT 315
PPPP + S LF++
Sbjct: 536 VANGPGSGPPPPAGGAGSRDALFES 560
Score = 29.3 bits (64), Expect = 5.3
Identities = 13/20 (65%), Positives = 13/20 (65%), Gaps = 2/20 (10%)
Query: 287 GYLSALHFL--PPPPPPPPP 304
G L H L PPPPPPPPP
Sbjct: 274 GGLLGPHLLGAPPPPPPPPP 293
Score = 28.9 bits (63), Expect = 7.0
Identities = 9/9 (100%), Positives = 9/9 (100%)
Query: 296 PPPPPPPPP 304
PPPPPPPPP
Sbjct: 286 PPPPPPPPP 294
Score = 28.9 bits (63), Expect = 7.0
Identities = 16/35 (45%), Positives = 18/35 (51%), Gaps = 11/35 (31%)
Query: 246 QGGGLVSEPGGDFQPSYYLPPPPPPLPPLPPLPPQ 280
Q G + +PG D LPPPPP PPL PQ
Sbjct: 821 QEDGKLGDPGSD------LPPPPP-----PPLAPQ 844
Score = 28.5 bits (62), Expect = 9.1
Identities = 12/23 (52%), Positives = 13/23 (56%)
Query: 255 GGDFQPSYYLPPPPPPLPPLPPL 277
GG + L PPPP PP PPL
Sbjct: 273 GGGLLGPHLLGAPPPPPPPPPPL 295
Score = 28.5 bits (62), Expect = 9.1
Identities = 11/17 (64%), Positives = 11/17 (64%)
Query: 265 PPPPPPLPPLPPLPPQP 281
PPPPPP PPL L P
Sbjct: 286 PPPPPPPPPLAELAGAP 302
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 58.2 bits (139), Expect = 1e-08
Identities = 32/56 (57%), Positives = 37/56 (66%), Gaps = 11/56 (19%)
Query: 260 PSYYLPPPP--PPLPPLPPLPP-QPQF-LPPGYLSALHFLPPPPPPPPPSSFSLTV 311
P+ LPPPP PPLPP PP PP QP F +PP LPPPPPPPPP+ ++TV
Sbjct: 677 PTLPLPPPPGFPPLPPPPPPPPPQPGFPMPPP-------LPPPPPPPPPAHPAVTV 725
Score = 47.0 bits (110), Expect = 2e-05
Identities = 83/302 (27%), Positives = 95/302 (31%), Gaps = 75/302 (24%)
Query: 64 EQEAALCAQGPKQASGAAAAAPAPVPVPAAS-LRPLSPGTPSGDADP---GPEGRAAACF 119
E+ A A G + SG APAP P+P A L PGTP G P E F
Sbjct: 412 EEPTATAAFGARD-SGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTF 470
Query: 120 FEQPPRGRNPGPRALQPVLGG--RSHVEPSERAAVAMPS-------LAGPPFGAEAAGSG 170
P +PG L+ G + H R + + L P E G
Sbjct: 471 GWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEG 530
Query: 171 YP-----GPLDLRRPMRTVPGPLFTDFVRPL---------NINP------------DRAL 204
P L P T P F P +I+P D L
Sbjct: 531 SPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDEDEELDLGL 590
Query: 205 GPEYPGGSSMHPYCPFPLGYLDAPPGVPLQQGFRHVSRSQ-----YQGGGLVSEPGGDFQ 259
GP P P P P G L V L S+ Q G E D
Sbjct: 591 GPRPP----PEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEM 646
Query: 260 PSYYL-----PPP------------PPPLPPLPPLPPQPQFLPPGYLSALHFLPPPPPPP 302
PS + P P P L P PLPP P F P LPPPPPPP
Sbjct: 647 PSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPP---------LPPPPPPP 697
Query: 303 PP 304
PP
Sbjct: 698 PP 699
Score = 45.8 bits (107), Expect = 6e-05
Identities = 25/55 (45%), Positives = 29/55 (52%), Gaps = 16/55 (29%)
Query: 259 QPSYYLPPPPPPLPPLPP-------LPPQPQFLPPGYLSALHFLPPPP--PPPPP 304
QP + +PPP PP PP PP +PP P PPG +PPPP PP PP
Sbjct: 700 QPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPAPPG-------VPPPPILPPLPP 747
Score = 43.9 bits (102), Expect = 2e-04
Identities = 48/194 (24%), Positives = 59/194 (30%), Gaps = 39/194 (20%)
Query: 150 AAVAMPSLAGPPFGAEAAGSGYPGPLDLRRPMRTVPGPLFTDFVRPLNINPDRALGPEYP 209
A A + PFGA G GP P + P T P A P
Sbjct: 342 ATAAFRGSSDLPFGAVGGTGGSSGP-----PFKAQPQDSAT-----FAHTPPPAQATPAP 391
Query: 210 GGSSMHPYCPFPLGYLDAPPGVPLQQGFRHVSRSQYQGGGLVSEPGGDFQPSYYLPPPPP 269
G S P+ + PP P + G+F+ + P PP
Sbjct: 392 GFKSAFSPYQTPVAHFPPPPEEPTATA------------AFGARDSGEFRRA----PAPP 435
Query: 270 PLPPLPPLPPQPQFLPPGYLSALHFLPPPPPPPPPSSFSL--TVLFDTDKENTDDQDAEV 327
PLPP PL + PPG PPPP +S L F E D
Sbjct: 436 PLPPAEPLAKEKPGTPPG-----------PPPPDTNSMELGGRPTFGWSPEPCDSPGTPT 484
Query: 328 LSGEPSQPSSQEQS 341
L P+ P S
Sbjct: 485 LESSPAGPEKPHDS 498
Score = 43.1 bits (100), Expect = 4e-04
Identities = 27/63 (42%), Positives = 28/63 (44%), Gaps = 17/63 (26%)
Query: 253 EPGGDFQPSYYLPPPPPPLPPL--------PPLPPQPQFLPPGYLSALHFLPPPPPPPPP 304
+PG P LPPPPPP PP PPLP P PP L PP PP PP
Sbjct: 700 QPGFPMPPP--LPPPPPPPPPAHPAVTVPPPPLPAPPGVPPPPIL-------PPLPPFPP 750
Query: 305 SSF 307
F
Sbjct: 751 GLF 753
Score = 40.0 bits (92), Expect = 0.003
Identities = 63/225 (28%), Positives = 84/225 (37%), Gaps = 39/225 (17%)
Query: 76 QASGAAAAAPAPVPVPAASLRPLSPG-----TPSGDADPGPEGRAAACFFEQPPRGRNPG 130
Q G+ + PAP P ++ P +PG TP+ GP C R G
Sbjct: 1359 QVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGPL-LLPVCPLPTGRRDERSG 1417
Query: 131 PRALQPVLGGRSHVEPSERAAVAMP---SLAGPPFGAEAAGSGYPGPLDLRRPMRTVPGP 187
P A PVL +E + +P LA P A + P P L P+ + P P
Sbjct: 1418 PLA-SPVL-----LETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCPPP 1471
Query: 188 LFTDFVRPLNINPDRALGPEYPGGSSMHPYCPFPLGY-LDAPPGVPLQQGF--RHVSRS- 243
+ RP +P L + G + P LG L PG P F H R+
Sbjct: 1472 MKRKPGRPRR-SPPSMLSLD---GPLVRPPAGAALGRELLLLPGQPQTPVFPSTHDPRTV 1527
Query: 244 --QYQGGGLVSEPGGDFQPSYYLPPPPPPLPPLPPLPPQPQFLPP 286
++ G+ P PPPPLPP PP PP P + P
Sbjct: 1528 TLDFRNAGI--------------PAPPPPLPPQPPPPPPPPPVEP 1558
Score = 36.6 bits (83), Expect = 0.033
Identities = 58/236 (24%), Positives = 76/236 (32%), Gaps = 54/236 (22%)
Query: 67 AALCAQGPKQASGAAAAAPAPVPVPAASLRPLSPGTPSGDADPGPEGRAAACFFEQPPRG 126
+A C + GAAA A V P L P PG P P P PP+
Sbjct: 653 SADCPKPMVVTPGAAAVAAPSVLAPTLPLPP-PPGFPPLPPPPPPP----------PPQP 701
Query: 127 RNPGPRALQPVLGGRSHVEPSERAAVAMPSLAGPPFGAEAAGSGYPGPLDLRRPMRTVPG 186
P P L P P+ V P L PP G P P + P+ P
Sbjct: 702 GFPMPPPLPPPPPPPPPAHPA--VTVPPPPLPAPP--------GVPPP-PILPPLPPFPP 750
Query: 187 PLFTDFVRPLNINPDRALGPEYPG-----------------GSSMHPYCPFPLGYLDAPP 229
LF + ++ LG ++ G G PY PF A
Sbjct: 751 GLFP----VMQVDMSHVLGGQWGGMPMSFQMQTQVLSRLMTGQGACPYPPFM-----AAA 801
Query: 230 GVPLQQGFRHVSRSQYQGGGLVSEPGGDFQPSYYLPPPPPPLPPLPPLPPQPQFLP 285
G + V+ Y+G +S G + PPLP P P P ++P
Sbjct: 802 AAAASAGLQFVNLPPYRGPFSLSNSGPGRGQHW------PPLPKFDPSVPPPGYMP 851
Score = 33.9 bits (76), Expect = 0.22
Identities = 17/34 (50%), Positives = 19/34 (55%), Gaps = 7/34 (20%)
Query: 260 PSYYLPPPPPPLPP-------LPPLPPQPQFLPP 286
P+ +PPPP P PP LPPLPP P L P
Sbjct: 721 PAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFP 754
Score = 33.9 bits (76), Expect = 0.22
Identities = 17/41 (41%), Positives = 20/41 (48%), Gaps = 8/41 (19%)
Query: 266 PPPPPLPPLPPLPPQPQFLPPGYLSALHFLPPPPPPPPPSS 306
P PP + PLP PP P PP PP PPP P ++
Sbjct: 1268 PEPPMMLPLPLQPPLPPPRPP--------RPPSPPPEPETT 1300
Score = 33.5 bits (75), Expect = 0.28
Identities = 17/36 (47%), Positives = 17/36 (47%), Gaps = 4/36 (11%)
Query: 265 PPPPPPLPPLPPLPPQPQFLPPGYLSALHFLPPPPP 300
PP PPP PP PP PP P A H PP P
Sbjct: 1280 PPLPPPRPPRPPSPPP----EPETTDASHPSVPPEP 1311
Score = 31.2 bits (69), Expect = 1.4
Identities = 20/53 (37%), Positives = 24/53 (45%), Gaps = 7/53 (13%)
Query: 259 QPSYYLPPP--PPPLPPLPPLPPQPQFLPPGYLSALHFLPPPP-----PPPPP 304
+P LP P PP PP PP PP P P ++ +PP P PP P
Sbjct: 1269 EPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTP 1321
Score = 28.5 bits (62), Expect = 9.1
Identities = 57/249 (22%), Positives = 72/249 (28%), Gaps = 35/249 (14%)
Query: 110 GPEGRAAACFFEQPPRG----RNPGPRALQPVLGGRSHVEPSERAAVAMPSLAGPPFGAE 165
G G + F QP P P P G +S P + P P
Sbjct: 359 GTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATA 418
Query: 166 AAGSGYPGPLDLRRPMRTVPGPLFTDFVRPL-NINPDRALGPEYPGGSSMHPYCPFPLGY 224
A G+ G R P P PL P GP P +SM G+
Sbjct: 419 AFGARDSGEF------RRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGW 472
Query: 225 LDAP---PGVP---------------LQQGFRHVSRSQYQGGGLVSEPGGDFQPSYYLPP 266
P PG P L + + Q + EP D + P
Sbjct: 473 SPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSP 532
Query: 267 PPPPLPPLPPLPPQPQFLPPGYLSALHFLPPPPPPPPPSSFSLTVLFDTDKENTDDQDAE 326
L PL P PG F P PP PSS L + T ++D+ +
Sbjct: 533 ISSSSSQLSPLAPFGTNSQPG------FRGPTPPSSRPSSTGLEDISPTPLPDSDEDEEL 586
Query: 327 VLSGEPSQP 335
L P P
Sbjct: 587 DLGLGPRPP 595
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 57.8 bits (138), Expect = 1e-08
Identities = 91/330 (27%), Positives = 115/330 (34%), Gaps = 59/330 (17%)
Query: 48 KIMAAQKVLKTQAAEEEQEAALCAQGPKQASGAAAAAPAPVPVPAASLRPLSPGTPSGDA 107
+I A + V + +A E + +AL A + SG P+ PA + R + GT G
Sbjct: 135 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPS----PAMARRSRAAGTEVGLP 190
Query: 108 DPGPEGRAAACFFEQPPRGRNPGPRALQPVLGGRSHVEPSERAAVAMPSLAG---PPFGA 164
P P R PR GPR S EPS AA PS G P
Sbjct: 191 RPAPSAR---------PRPPTEGPRKSVSSASEHSTTEPSP-AARRRPSAGGGLQRPASR 240
Query: 165 EAAGSGYP-------GPLDLRRPMR----TVPGPLFTDFVRPLNINPDR-----ALGPEY 208
+ S P GP P + P P +RP + P R ALGP
Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPL- 299
Query: 209 PGGSSMHPYCPFPLGYL--DAPPGVPLQQGFRHVSRSQYQGGGLVSEPGGDFQPSYYLPP 266
SS P P L APP +P ++ Q ++ P PS P
Sbjct: 300 ---SSSPLATPSPSAALQSQAPPTLPATPHSSSLT-CQLATPLPLAPPSPSAPPSLQTLP 355
Query: 267 PPPPLPP--------LPPLPPQPQFLPPGYLSALHFLPP--PP---------PPPPPSSF 307
PP PP P L FLP LS L PP PP PP PP+S
Sbjct: 356 SPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASP 415
Query: 308 SLTVLFDTDKENTDDQDAEVLSGEPSQPSS 337
L+ L + + +L S P S
Sbjct: 416 PLSPLATPSPQAPNALAVHLLQAPFSPPPS 445
Score = 53.5 bits (127), Expect = 3e-07
Identities = 63/243 (25%), Positives = 86/243 (35%), Gaps = 32/243 (13%)
Query: 77 ASGAAAAAPAPVPVPAASLR----PLSPGTPSGD------ADPGPEGRAAACFFEQPPRG 126
A G +++P P P+A+L+ P P TP A P P + PP
Sbjct: 295 ALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSP---SAPPSL 351
Query: 127 RN-PGPRALQPVLGGRSHVEPSERAAVAMPSLAGPPFGAEAAGSGYPGPLDLRRPMRTVP 185
+ P P A P S P+ +A + L PP A P P++ P
Sbjct: 352 QTLPSPPATPPSQATTSLGSPTLQATHSF--LPSPPLSPLATPPPQAPPALALPPLQAPP 409
Query: 186 GPLFTDFVRPLNINPDRALGPEYPGGSSMH----PYCPFPLGYLDAPPGVPLQQGFRHVS 241
P + + PL P+ P ++H P+ P P + AP P +
Sbjct: 410 SPPASPPLSPL-----ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA 464
Query: 242 RSQYQGGGLVSEPGGDFQPSYYLPPPPPPLPPL-PPLPPQPQFLPPGYLSALHFLPPPPP 300
Q P P +PP PP PP+ P P PQ PP L PPP
Sbjct: 465 TPPSQA------PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ 518
Query: 301 PPP 303
PP
Sbjct: 519 APP 521
Score = 52.4 bits (124), Expect = 6e-07
Identities = 72/263 (27%), Positives = 82/263 (31%), Gaps = 56/263 (21%)
Query: 71 AQGPKQASGAAAAAPAPVPVPAASLRPLSP-GTPSGDADPGPEGRAAACFFEQPPRGRNP 129
A P QA A A P P + PLSP TPS A A A Q P P
Sbjct: 390 ATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP-----NALAVHLLQAPFSPPP 444
Query: 130 GPRALQPVLGGRSH-VEPSERA-AVAMPSLAGPPFGAEAAGSGYPG-------------- 173
P P S V PS + A PSLA PP + P
Sbjct: 445 SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 504
Query: 174 ----PLDLRRPMRTVPGPLFTDFVRPLNINPDRALGPEYPGGSSMHPYCPFPLGYLDAPP 229
PL L +P P L T ++ L P +PG + P P+ L PP
Sbjct: 505 LAAPPLQLAKPPPQAPPALATPPLQALPSPP-----ASFPGQAPFSPSASLPMSPLATPP 559
Query: 230 GVPLQQGFRHVSRSQYQGGGLVSEPGGDFQPSYYLPPPPPPLP----PLPPLPPQPQFLP 285
P P +PP PP P P P P P
Sbjct: 560 P---------------------QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV 598
Query: 286 PGYLSALHFLPPPPPPPPPSSFS 308
G L P PPPPP S S
Sbjct: 599 SGPRLTLALAPGPPPPPSRSPSS 621
Score = 52.0 bits (123), Expect = 8e-07
Identities = 73/300 (24%), Positives = 104/300 (34%), Gaps = 44/300 (14%)
Query: 46 RQKIMAAQKVLKTQ---AAEEEQEAALCAQGPKQASGAAAAAPAPVPVPAASLRPLSPGT 102
R+ + +A + T+ AA A Q P S +++A P P + +P
Sbjct: 206 RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA 265
Query: 103 PSGDADPGPEGRAAACFFEQPPRGRNPGPRALQPVLGGRSH---VEPSERAAV---AMPS 156
P+ + P P+G A +PP+ P A P LG S PS AA+ A P+
Sbjct: 266 PAHPSQPKPKGLQAL----RPPQVTPPRKDAA-PALGPLSSSPLATPSPSAALQSQAPPT 320
Query: 157 LAGPPFGAEAAGSGYPGPLDLRRPMRTVPGPLFTDFVRPLNINPDRALGPEYPGGSSMHP 216
L P + PL L P + P L T P P + H
Sbjct: 321 LPATPHSSSLTCQ-LATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHS 379
Query: 217 YCPFP-----------------LGYLDAPPGVPLQQGFRHVSRSQYQGGGLVSEPGGDFQ 259
+ P P L L APP P ++ Q ++
Sbjct: 380 FLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV---HLL 436
Query: 260 PSYYLPPPPPPL---------PPLPPLPPQPQFLPPGYLSALHFLPPPPPPPPPSSFSLT 310
+ + PPP PP+ PP+ P P PP + +PP PP PP S S T
Sbjct: 437 QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 496
Score = 43.1 bits (100), Expect = 4e-04
Identities = 61/249 (24%), Positives = 82/249 (32%), Gaps = 36/249 (14%)
Query: 83 AAPAPVPVPAASLRPLSPGTPSGDADPG---PEGRAAACFFEQPPRG--RNPGPRALQPV 137
A P+P P+ P P TP A P +A F PP P P+A +
Sbjct: 341 APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 400
Query: 138 LGGRSHVEPSERAAVAMPSLAGPPFGA---------EAAGSGYPGPLDLRRPMRTVPGPL 188
PS A+ + LA P A +A S P P ++ P P
Sbjct: 401 ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP-PVQAPFSPPASPP 459
Query: 189 FTDFVRPLNINPDRALGPEY---PGGSSMHPYCPFPLGYLDAPPGVPLQQGFRHVSRSQY 245
+ P + P P P + P P APP PL +++
Sbjct: 460 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP--PLAAPPLQLAKPPP 517
Query: 246 QGGGLVSEPGGDFQPSYYLPPPPPPLP-----------PLPPLPPQPQFLPPGYLSALHF 294
Q ++ P P LP PP P P+ PL P PP + L
Sbjct: 518 QAPPALATP-----PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 572
Query: 295 LPPPPPPPP 303
+PP PP P
Sbjct: 573 VPPSPPASP 581
Score = 41.6 bits (96), Expect = 0.001
Identities = 78/298 (26%), Positives = 97/298 (32%), Gaps = 80/298 (26%)
Query: 73 GPKQASGAAAAAPAPVPV---------PAASLRP---LSPGTPSGDADPGPEGR------ 114
GP +++G ++ PA P PA + P SPG SG PGP G+
Sbjct: 78 GPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 137
Query: 115 -----AAACFFEQPPRG----------RNPGPRALQPVLGGRSHVEPSE-------RAAV 152
A E P R P P P + RS +E +A
Sbjct: 138 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR 197
Query: 153 AMPSLAGPPFGAEAA---GSGYPGPLDLRRPMRTVPGPLFTDFVRPLNINPDRALGPEYP 209
P GP +A + P P RRP + G L R L+ + P
Sbjct: 198 PRPPTEGPRKSVSSASEHSTTEPSPAARRRP--SAGGGLQRPASRSLSSSATPLSSPARS 255
Query: 210 GGSS-------MHPYCPFPLGY--LDAPPGVPLQQGFRHVSRSQYQGGGLVSEPGGDFQP 260
G S+ HP P P G L P P ++ G L S P P
Sbjct: 256 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL------GPLSSSPLATPSP 309
Query: 261 SYYL----PPPPPPLP-----------PLPPLPPQPQFLPPGYLSALHFLPPPPPPPP 303
S L PP P P PLP PP P P +L LP PP PP
Sbjct: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPP-----SLQTLPSPPATPP 362
Score = 28.9 bits (63), Expect = 7.0
Identities = 27/104 (25%), Positives = 30/104 (28%), Gaps = 6/104 (5%)
Query: 72 QGPKQASGAAAAAPAPVPVPAASLRPLSPGTPSGDAD-PGPEGRAAACFFEQPPRGRNPG 130
Q P + P P P P TP D GP A PP R+P
Sbjct: 561 QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS 620
Query: 131 PRALQPVLGGRSHVEPSERAAVAMPSLAGPPFGAEAAGSGYPGP 174
P L G S A L G G E + P P
Sbjct: 621 STLSGPDLAGH-----SSSATSTPEELRGYDSGPEGGAAASPPP 659
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 57.8 bits (138), Expect = 1e-08
Identities = 67/233 (28%), Positives = 82/233 (35%), Gaps = 45/233 (19%)
Query: 95 LRPLSPGTPSGDADPGPEGRAAACFFEQPPRGRNPGPR---ALQPVLGGRSHVEPSERAA 151
L+P+ P P+ P PE + F PP PGP P G P A
Sbjct: 638 LQPMGPTCPTPAPVPPPEAPSP---FRAPPF-HPPGPMPSVGSMPSAGPMPSAGPMPSAG 693
Query: 152 VAMPSLAGPPFGAEAAGSGYPGPLDLRRPMRTVPGP------------LFTDFVRPLNIN 199
+ GPP A G PG + + P R +PGP L P I
Sbjct: 694 PVPSARPGPPTTANHLGLSVPGLVSV--PPRLLPGPENHRAGSNEDPILAPSGTPPPTIP 751
Query: 200 PDRALGPEYPGGSSMHPYCPFPLGYLDAPPGVPLQQGFRHVSRSQYQGGGLVSEPGGDFQ 259
PD G P + +H D ++ +S +V P G
Sbjct: 752 PDETFGGRVPRPAFVH---------YDKEEASDVE-----ISLESDSDDSVVIVPEG--L 795
Query: 260 PSYYLPPP----PPPLPPLPP---LPPQPQFLPPGYLSALHF-LPPPPPPPPP 304
P PPP PPP+ P P PP P P L A LPPPPPPPPP
Sbjct: 796 PPLPPPPPSGATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPP 848
Score = 50.1 bits (118), Expect = 3e-06
Identities = 79/310 (25%), Positives = 107/310 (34%), Gaps = 72/310 (23%)
Query: 74 PKQASGAAAAAPAPVPVPAA----------------------SLRPLSPGTPSGDADPGP 111
P Q G PAPVP P A S P+ P A P P
Sbjct: 637 PLQPMGPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSAGPVP 696
Query: 112 EGRAAACFFEQPPRGRN------PGPRALQPVL--GGRSHVEPSERAAVAMPSLAGPPF- 162
R PP N PG ++ P L G +H S + PS PP
Sbjct: 697 SARPG------PPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSGTPPPTI 750
Query: 163 -GAEAAGSGYPGPLDL---RRPMRTVPGPLFTDFVRPLNINPDRA--LGPEYPGGSSMHP 216
E G P P + + V L +D + I P+ L P P G++ P
Sbjct: 751 PPDETFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPP 810
Query: 217 YCPFPLGYLDAPPGVPLQQGFRHVSRSQYQGGGLVSEPGGDFQPSYYLPPPPPPLPPLPP 276
P G A P VP ++ + L + PG P PPPPPP P P
Sbjct: 811 IAP--TGPPTASPPVPAKE----------EPEELPAAPG-PLPP----PPPPPPPVPGPV 853
Query: 277 LPPQPQFLPPGYLSALHFLPPPPPPPPPSSFSLTVL----FDTDKENTDDQDAEVLSGEP 332
P PQ +P G P PP LTV+ D ++E ++++ E E
Sbjct: 854 TLPPPQLVPEG--------TPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEE 905
Query: 333 SQPSSQEQSD 342
+ +E+ +
Sbjct: 906 EEEDFEEEEE 915
Score = 31.6 bits (70), Expect = 1.1
Identities = 22/73 (30%), Positives = 28/73 (38%), Gaps = 1/73 (1%)
Query: 266 PPPPPLPPLPPLPPQPQFLPPGYLSALHFLPP-PPPPPPPSSFSLTVLFDTDKENTDDQD 324
P PPL P+ P P P +PP + PP PP P PS S+
Sbjct: 633 PRVPPLQPMGPTCPTPAPVPPPEAPSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSA 692
Query: 325 AEVLSGEPSQPSS 337
V S P P++
Sbjct: 693 GPVPSARPGPPTT 705
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 57.8 bits (138), Expect = 1e-08
Identities = 27/48 (56%), Positives = 28/48 (58%), Gaps = 8/48 (16%)
Query: 265 PPPPPPLPPLPPLPPQPQFLPP--------GYLSALHFLPPPPPPPPP 304
PPPPPP PPLPP PPQP + P L A PPPPPPPPP
Sbjct: 1958 PPPPPPPPPLPPAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPP 2005
Score = 45.4 bits (106), Expect = 7e-05
Identities = 26/66 (39%), Positives = 26/66 (39%), Gaps = 14/66 (21%)
Query: 249 GLVSEPGGDFQPSYYLPPPPPPLPPLPPLPPQPQFLPPGYLSALHFLPPPPPPPPPSSFS 308
G V P P PP PPP PP PP PP P PPPPPP P
Sbjct: 1978 GPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPP--------------PPPPPPSAPPQVQ 2023
Query: 309 LTVLFD 314
L V D
Sbjct: 2024 LPVSLD 2029
Score = 37.0 bits (84), Expect = 0.026
Identities = 17/32 (53%), Positives = 17/32 (53%)
Query: 265 PPPPPPLPPLPPLPPQPQFLPPGYLSALHFLP 296
PPPPPP PP PP PP P P L LP
Sbjct: 2000 PPPPPPPPPPPPPPPPPSAPPQVQLPVSLDLP 2031
Score = 33.9 bits (76), Expect = 0.22
Identities = 15/44 (34%), Positives = 25/44 (56%), Gaps = 1/44 (2%)
Query: 296 PPPPPPPPPSSFSLTVLFDTDKENTDDQDAEVLSGEPSQPSSQE 339
PPPPPPPPP S SL+ T+++N + + + + + +E
Sbjct: 3119 PPPPPPPPPPSSSLSGQ-QTEQQNKESEKKQTKPNKVKKIKEEE 3161
Score = 30.8 bits (68), Expect = 1.8
Identities = 15/40 (37%), Positives = 17/40 (42%)
Query: 265 PPPPPPLPPLPPLPPQPQFLPPGYLSALHFLPPPPPPPPP 304
PPPPPP P PP P L ++ P P PP
Sbjct: 2009 PPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPP 2048
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 57.4 bits (137), Expect = 2e-08
Identities = 69/235 (29%), Positives = 85/235 (36%), Gaps = 46/235 (19%)
Query: 89 PVPAASLRPLSPGTPSGDADPGPEGRAAACFFEQPPRGRNPGPRALQPVLGGRSHVEPSE 148
PVPA+ P T + P P A NP P +L R S
Sbjct: 324 PVPASVGSTSGPATTPLASAPRPAAPA-----------NNPPPPSLMSTTQSRPPWMNSG 372
Query: 149 RAAVAMPSLAGPPFGAEAAGSGYPG--PLDLRRPMRTVPGPLFTDFVRPLNINPDRALGP 206
PS + P G G G PG P P+ ++ G P+ NP+ GP
Sbjct: 373 ------PSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGG---HGGHPMQHNPN---GP 420
Query: 207 EYPGGSSMHPYC---PFPLGYLDAPP------GVPLQQGFRHVSRSQYQGGGLVSEPGGD 257
P P P P G+ PP P+ G + +QG G++ P
Sbjct: 421 PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRL----HQGKGMMPPP--- 473
Query: 258 FQPSYYLPPPPPPLPPLPPLPPQPQFLPPGYLSALHFLPPPPPPPPPSSFSLTVL 312
P +PPPPPP PP PP LPP PPPPPPP S S T L
Sbjct: 474 --PMGMMPPPPPPPSGQPPPPPSGP-LPPWQQQQQQ--PPPPPPPSSSMASSTPL 523
Score = 53.5 bits (127), Expect = 3e-07
Identities = 63/242 (26%), Positives = 81/242 (33%), Gaps = 30/242 (12%)
Query: 79 GAAAAAPAPVPVPAASLRPLSPGTPSGDADPGPEGRAAACFFEQPPRGRNPGPRALQPVL 138
G P P P SL G P GP + + PP N GP
Sbjct: 388 GGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPP----WMQPPPPPMNQGPHP----- 438
Query: 139 GGRSHVEPSERAAVAMPSLAGPPFGAEAAGSGYPGPLDLRRPMRTVP---------GPLF 189
G P ++ + P +G + G P P+ + P P GPL
Sbjct: 439 PGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPL- 497
Query: 190 TDFVRPLNINPDRALGPEYPGGSSMHPYCPFPLGYLDAPPGVPLQQGFRHVSRSQYQGGG 249
P + P P SSM P P + G + Q Q
Sbjct: 498 -----PPWQQQQQQPPPPPPPSSSMASSTPLP--WQQNTTTTTTSAGTGSIPPWQQQQAA 550
Query: 250 LVSEPGGDFQPSY--YLPPPPPPLPPLPPLPPQPQFLPPGYLSALHFLPPPPPPPP--PS 305
+ PG +P PP PPLPP P P PP + + + PPPPPPPP PS
Sbjct: 551 AAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPPPPMDPS 610
Query: 306 SF 307
+F
Sbjct: 611 NF 612
Score = 46.2 bits (108), Expect = 4e-05
Identities = 22/58 (37%), Positives = 28/58 (48%), Gaps = 16/58 (27%)
Query: 265 PPPPPPLPP-------LPPLPPQPQFLPPGYLSALHF---------LPPPPPPPPPSS 306
PPPPPP PP PP PP P P +++ + +PP PPPPPP +
Sbjct: 582 PPPPPPPPPGSAGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPFGMPPAPPPPPPQN 639
Score = 36.6 bits (83), Expect = 0.033
Identities = 48/191 (25%), Positives = 66/191 (34%), Gaps = 28/191 (14%)
Query: 88 VPVPAASLRPLSPGTPSGDADPGPEGRAAACFFEQPPRGRNPGPRALQPVLGGRSHVEPS 147
+P P + P P PSG P P G +Q P P + S P
Sbjct: 470 MPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSM----ASSTPLPW 525
Query: 148 ERAAVAMPSLAG----PPFGAE-AAGSGYPGPLDLRRPMRTVPGPLFTDFVRPLNINPDR 202
++ + AG PP+ + AA + PG ++ VP P P P
Sbjct: 526 QQNTTTTTTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPP 585
Query: 203 ALGPEYPGGSSMHPYCPFPLGYLDAPPGVPLQQGFRHVSRSQYQGGGLVSEPGGDFQPSY 262
P P GS+ Y P P PP P+ + G G+ P +
Sbjct: 586 ---PPPPPGSAGMMYAPPP------PPPPPMDPS----NFVTMMGMGVAG------MPPF 626
Query: 263 YLPPPPPPLPP 273
+PP PPP PP
Sbjct: 627 GMPPAPPPPPP 637
>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
Length = 1497
Score = 57.4 bits (137), Expect = 2e-08
Identities = 83/278 (29%), Positives = 99/278 (35%), Gaps = 75/278 (26%)
Query: 73 GPKQASGAAAAAPAPVPVPAASLR-------------PLSPGTPSGD-ADPGPEGRAAAC 118
GPK +SG+ P PV LR P+ P P GD + GP G
Sbjct: 665 GPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEP 724
Query: 119 FFEQPPRG-RNPGPRALQPVLGGRSHVEP-SERAAVAMPSLAGPPFGAEAAG----SGYP 172
P PG + G H P E+ MP + GPP + G +G
Sbjct: 725 GMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQ 784
Query: 173 GPLDLR----RP-------------------MRTVPGPLFTDFVRPLNINPDRALGPEYP 209
GP L RP M TVPGP P A+GP P
Sbjct: 785 GPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPP----------GPPGAMGPPGP 834
Query: 210 GGSSMHPYCPFPLGYLDAPPGVPLQQGFRHVSRSQYQGGGLVSEPGGDFQPSYYLPPPPP 269
G+ P P G P G+P G + V Q G PG P +P PP
Sbjct: 835 PGA------PGPAG----PAGLP---GHQEVLNLQ----GPPGPPGPRGPPGPSIPGPPG 877
Query: 270 PL-PPLPPLPPQPQFLPPG-YLS-ALHFLPPPPPPPPP 304
P PP LP P PPG +LS + FL PP PP P
Sbjct: 878 PRGPPGEGLPGPPG--PPGSFLSNSETFLSGPPGPPGP 913
Score = 50.4 bits (119), Expect = 2e-06
Identities = 70/248 (28%), Positives = 82/248 (33%), Gaps = 53/248 (21%)
Query: 109 PGPEGRAAACFFEQPPRGRNP-GPRAL---QPVLGGRSHVEPSERAAVAMPSLAGPPFGA 164
PGP G A PP P GP L Q VL + P PS+ GPP
Sbjct: 820 PGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPR 879
Query: 165 EAAGSGYPGPLDLRRPMRTVPGPLFTDFVRPLNINPDRALGPEYPGGSSMHPYCPFPLGY 224
G G PGP PG ++ L+ P GP P G P P G+
Sbjct: 880 GPPGEGLPGPPG-------PPGSFLSNSETFLSGPP----GPPGPPGPKGDQGPPGPRGH 928
Query: 225 --------------------LDAPPGVPLQQGFRHVSRSQYQGG--GLVSEP--GGDFQP 260
L PPG P QG + G G+ S P GG
Sbjct: 929 QGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSST 988
Query: 261 SYYLPPPPPPLPPLPP--LPPQPQFLPP------------GYLSALHFLPPPPPPPPPSS 306
Y PP PP PP PP + Q + YLS + P PP PP P +
Sbjct: 989 MYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGPVT 1048
Query: 307 FSLTVLFD 314
FD
Sbjct: 1049 TITGETFD 1056
Score = 39.3 bits (90), Expect = 0.005
Identities = 70/282 (24%), Positives = 84/282 (29%), Gaps = 79/282 (28%)
Query: 97 PLSPGTPSGDADPGPEGRAAACFFEQPPRGRNP-GPRALQPVLGGRSHVEP------SER 149
P +PG P PGP+G P P G R + +G R P ER
Sbjct: 587 PGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGER 646
Query: 150 AAVAMPSLAGPPFGAEAAG----SGYPGPLDLRRP------------------------- 180
A P GPP + G SG PGP P
Sbjct: 647 GAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPMGPP 706
Query: 181 -------------------MRTVPGPLFTDFVRPL--NINPDRALGPEYPGGSSMHPYCP 219
MR +PG + + PD GP G + P
Sbjct: 707 GPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIR 766
Query: 220 FPLGYLDAPPGVPLQQGFRHVSRSQYQGG-----GLVSEPGG-----DFQPSYYLPPPPP 269
P G P G P + G Q G G+ EPG + S L P P
Sbjct: 767 GPPG----PSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGP 822
Query: 270 PLPPLPPLPPQPQFLP--------PGYLSALHFLPPPPPPPP 303
P PP PP P P PG+ L+ PP PP P
Sbjct: 823 PGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGP 864
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 57.4 bits (137), Expect = 2e-08
Identities = 77/281 (27%), Positives = 99/281 (35%), Gaps = 52/281 (18%)
Query: 53 QKVLKTQAAEEEQEAALCAQGPKQASGAAAAAPAPVPV-------PAASLRPLSPGTPSG 105
Q L+ +E + L A+GP + A+ AP P P A L P P
Sbjct: 693 QDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDS 752
Query: 106 DADPGPEGRAAACFFEQPPRGRNPGPRAL-----QPVLGGRSHV------EPSERAAVAM 154
A P P + A P +G PGP + Q LG H+ P R
Sbjct: 753 QASPAPAPQIPAA---APLKG--PGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRP 807
Query: 155 PSLAGPPFGAEAAGSGYPGPLDLRRPMRTVPGPLFTDF---VRPLNINP-DRALGPEYPG 210
S++ PP +P P P T+PG V P NP A GP P
Sbjct: 808 QSVSRPPSEPPL----HPCPPPQAPP--TLPGIFVIQNQLGVPPPASNPAPTAPGPPQP- 860
Query: 211 GSSMHPYCPFPLGYLDAPPGVPLQQGFRHVSRSQYQGGGLVSEPGGDFQPSYYLPPPPPP 270
+ P P G L P +P V+ S L + DFQ + PP
Sbjct: 861 --PLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQF----PPSQ 914
Query: 271 LPPLPPLPPQPQFLPPGYLSALHFLPPP--PPPPPPSSFSL 309
P P PP LH +P P PPPPPP +F +
Sbjct: 915 GPHKSPTPPP----------TLHLVPEPAAPPPPPPRTFQM 945
Score = 44.7 bits (104), Expect = 1e-04
Identities = 63/248 (25%), Positives = 87/248 (35%), Gaps = 37/248 (14%)
Query: 83 AAPAPVPVPAASLRPLSPGTPSGDADPGPEGRAAACFFEQPPRGRNPGPRALQPVLGGRS 142
+A A + P ++P +P +G+A P + A + PP P P LQ +
Sbjct: 591 SAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAP---QAPPAVSTPLPLGLQQPQAQQP 647
Query: 143 HVEPSERAAVAMPSLAGPPFGAEAAGSGYPGPLDLRRPMRTVPGPLFTDFVRPLNINPDR 202
P+ +AA A P P A S P + L +P P + T + + +R
Sbjct: 648 PQAPTPQAA-APPQATTPQPSPGLASS--PEKIVLGQPPSATPTAILTQDSLQMFLPQER 704
Query: 203 ------ALGPEYPGGSSMHPYCPFPLGYLDAPPGVPLQQGF-----------RHVSRSQY 245
A GP +S+ P P D P P+ +G Q
Sbjct: 705 SQQPLSAEGPHLSVPASVIVSAPPPAQ--DPAPATPVAKGAGLGPQAPDSQASPAPAPQI 762
Query: 246 QGGGLVSEPGGDFQPSY----------YLPPPPPPLPPL-PPLPPQPQFLPPGYLSALHF 294
+ PG PS +LP P P PP PP PQ PP LH
Sbjct: 763 PAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSE-PPLHP 821
Query: 295 LPPPPPPP 302
PPP PP
Sbjct: 822 CPPPQAPP 829
Score = 30.4 bits (67), Expect = 2.4
Identities = 17/43 (39%), Positives = 19/43 (44%), Gaps = 11/43 (25%)
Query: 266 PPPPPL-------PPLPPLPPQPQFLPPGYLSALHFLPPPPPP 301
PPPPP PP PP PP P G ++ PPP P
Sbjct: 1333 PPPPPATLKVAEPPPRPPPPPP----PTGQMNGTVDHPPPAAP 1371
Score = 30.4 bits (67), Expect = 2.4
Identities = 16/47 (34%), Positives = 19/47 (40%), Gaps = 16/47 (34%)
Query: 265 PPPPPPLPPLPPLPPQPQFLPPGYLSALHFLPPPPPPPPPSSFSLTV 311
PPPPP + PP+P PPPPPP + TV
Sbjct: 1333 PPPPPATLKVAEPPPRP----------------PPPPPPTGQMNGTV 1363
Score = 30.0 bits (66), Expect = 3.1
Identities = 15/35 (42%), Positives = 17/35 (48%), Gaps = 5/35 (14%)
Query: 271 LPPLPPLPPQPQFLPPGYLSALHFLPPPPPPPPPS 305
L P+ PP PP L P PPPPPPP+
Sbjct: 1327 LDPVHQPPP-----PPATLKVAEPPPRPPPPPPPT 1356
Score = 29.3 bits (64), Expect = 5.3
Identities = 67/260 (25%), Positives = 85/260 (32%), Gaps = 56/260 (21%)
Query: 73 GPKQASGAAAAAPAPVPVPAASLRPLS----PGTPSGDADPGPEGRAAACFFEQPPRGRN 128
GP A GAAA A P + S L P + A P+ QP
Sbjct: 142 GPTGAGGAAAVAAGPQALFPGSTDLLGLQGPPTVLTHQALVPPQDVVNKALSVQP----- 196
Query: 129 PGPRALQPVLGGRSHVEPSERAAVAMPSLAGPPFGAEAAGSGYPGPLDLRRPMRTVPGPL 188
LQPV G ++P +P L G P G + G L L P++ V P
Sbjct: 197 ----FLQPVGLGNVTLQP-------IPGLQGLPNG--SPGGATAATLGL-APIQVVGQP- 241
Query: 189 FTDFVRPLNINPDRALGPEYPG----GSSMHPYCPFPLGYLDAPP---GVPLQQGFRHV- 240
V LN + L + P S+ P P L P G+ +Q+
Sbjct: 242 ----VMALNTPTSQLLAKQVPVSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNLSAAV 297
Query: 241 -----SRSQYQGGGLVSEPGGDFQPSYYLPPPPPPLPPLPPLPPQPQFLPPGYLSALHFL 295
S + G G S P G P PL P L P P + LH
Sbjct: 298 ATTLNGNSVFGGAGAASAPTG--------TPSGQPLAVAPGLGSSPLVPAPNVI--LHRT 347
Query: 296 PPPPPPP-----PPSSFSLT 310
P P P PP + LT
Sbjct: 348 PTPIQPKPAGVLPPKLYQLT 367
>gi|21955170 single stranded DNA binding protein 3 isoform a [Homo
sapiens]
Length = 388
Score = 57.4 bits (137), Expect = 2e-08
Identities = 72/249 (28%), Positives = 93/249 (37%), Gaps = 48/249 (19%)
Query: 80 AAAAAPAPVPVPAASLRPLSPGTPSGDADPGPEGRAAACFFEQPPRGRNPGPRALQPVLG 139
+AAAAP+PV P + G P G PG FF+ PP G P P A P
Sbjct: 93 SAAAAPSPV----LGNIPPNDGMPGGPIPPG--------FFQGPP-GSQPSPHAQPPPHN 139
Query: 140 GRSHVEPSERAAVAMPSLAGPPFGAEAAGSGYPGPLDLRRPMRTVPG--PLFTDFVRPLN 197
S + P + ++ P AG P G+ PG VPG PL + + P
Sbjct: 140 PSSMMGPHSQPFMS-PRYAGGPRPPIRMGNQPPGG---------VPGTQPLLPNSMDPTR 189
Query: 198 -------------INPDRALGPEYPG----GSSMHPYCPFPLGYLDAPPGVPLQQGFRHV 240
+NP R +GP PG GS M P P LG A PG+ + G
Sbjct: 190 QQGHPNMGGSMQRMNPPRGMGPMGPGPQNYGSGMRPP-PNSLG--PAMPGINMGPG---A 243
Query: 241 SRSQYQGGGLVSEPGGDFQPSYYLPPPPPPLPPLPPLPPQPQFLPPGYLSALHFLPPPPP 300
R S P P Y+ PP PP P+ P P + + P PP
Sbjct: 244 GRPWPNPNSANSIPYSSSSPGTYVGPPGGGGPPGTPIMPSPADSTNSSDNIYTMINPVPP 303
Query: 301 PPPPSSFSL 309
S+F +
Sbjct: 304 GGSRSNFPM 312
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 57.0 bits (136), Expect = 2e-08
Identities = 83/307 (27%), Positives = 104/307 (33%), Gaps = 71/307 (23%)
Query: 48 KIMAAQKVLKTQAAEEEQEAALCAQGPKQASGAAAAAPAPVPVPAASLRPLSPGTPSGDA 107
+I A + V + +A E + +AL A + SG P+P A + R + GT G
Sbjct: 135 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSP----AMARRSRAAGTEVGLP 190
Query: 108 DPGPEGRAAACFFEQPPRGRNPGPRALQPVLGGRSHVEPSERAAVAMPSLAGP---PFGA 164
P P R PR GPR S EPS AA PS G P
Sbjct: 191 RPAPSAR---------PRPPTEGPRKSVSSASEHSTTEPSP-AARRRPSAGGGLQRPASR 240
Query: 165 EAAGSGYP-------GPLDLRRPMRTV----PGPLFTDFVRPLNINPDR-----ALGP-- 206
+ S P GP P P P +RP + P R ALGP
Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300
Query: 207 ------EYPGGSSMHPYCP-----FPLGYLDAPPGVPLQQGFRHVSRSQYQGGGLVSEPG 255
P G+ P P PL PP PL ++ P
Sbjct: 301 SSPLATPSPSGTKARPVPPPDNAATPLP-ATLPPSPPLATPLP------------LAPPS 347
Query: 256 GDFQPSYYLPPPPPPLPP--------LPPL--PPQPQFLPPGYLSALHFLPPPPPPPPPS 305
PS P PP PP PP+ PP Q +PP + H L P PPS
Sbjct: 348 PSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPP--IQVPHSLTSPSLQAPPS 405
Query: 306 SFSLTVL 312
+L+ L
Sbjct: 406 PLALSSL 412
Score = 57.0 bits (136), Expect = 2e-08
Identities = 69/249 (27%), Positives = 83/249 (33%), Gaps = 29/249 (11%)
Query: 71 AQGPKQASGAAAAAPAPVPVPAASLRPLSP-GTPSGDADPGPEGRAAACFFEQPPRGRNP 129
A P QA A P P + PLSP TPS A A A Q P P
Sbjct: 615 ATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAP-----NALAVHLLQAPFSPPP 669
Query: 130 GPRALQPVLGGRSH-VEPSERA-AVAMPSLAGPPFGAEAAGSGYPGPLDLRRPMRTVPGP 187
P P S V PS + A PSLA PP + P P P P
Sbjct: 670 SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 729
Query: 188 LFTDFVRPLNINPDRALGPEYPGGSSMHPYCPFPLGY--LDAPPGVPLQQGFRHVSRSQY 245
L PL + P P ++ P P L L PP P +++
Sbjct: 730 LAAP---PLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPP 786
Query: 246 QGGGLVSEPGGDFQPSYYLPPPPPPLP-----------PLPPLPPQPQFLPPGYLSALHF 294
Q ++ P P LP PP P P+ PL P PP + L
Sbjct: 787 QAPPALATP-----PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 841
Query: 295 LPPPPPPPP 303
+PP PP P
Sbjct: 842 VPPSPPASP 850
Score = 56.6 bits (135), Expect = 3e-08
Identities = 59/229 (25%), Positives = 80/229 (34%), Gaps = 22/229 (9%)
Query: 86 APVPVPAASLRPLSPGTPSGDADPGPEGRAAACFFEQPPRGRNPGPRALQPVLGGRSHVE 145
AP P+ AS PL+ TP + P P A C + PP P +
Sbjct: 542 APPPLQTASA-PLT--TPHLETPPCP----APCPLQAPPSPLTTPPPETPSSIATPPPQA 594
Query: 146 PSERAAVAMPSLAGPPFGAEAAGSGYPGPLDLRRPMRTVPGPLFTDFVRPLNINPDRALG 205
P A+ + L PP A P P++ P P + + PL
Sbjct: 595 PPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPL-----ATPS 649
Query: 206 PEYPGGSSMH----PYCPFPLGYLDAPPGVPLQQGFRHVSRSQYQGGGLVSEPGGDFQPS 261
P+ P ++H P+ P P + AP P + Q P P
Sbjct: 650 PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA------PPSLAAPP 703
Query: 262 YYLPPPPPPLPPLPPLPPQPQFLPPGYLSALHFLPPPPPPPPPSSFSLT 310
+PP PP PP+ P P PP + +PP PP PP S S T
Sbjct: 704 LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSAT 752
Score = 52.8 bits (125), Expect = 5e-07
Identities = 69/263 (26%), Positives = 91/263 (34%), Gaps = 30/263 (11%)
Query: 84 APAPVPVPAASLRPLSPGTPSGDADPGPEGRAAACFFEQPPRGRNPGPRALQPVLGGRSH 143
AP P+ P + L P TPS A P P+ A PP P P L P+
Sbjct: 565 APCPLQAPPSPLTTPPPETPSSIATPPPQAPPALA---SPPLQGLPSP-PLSPLA----- 615
Query: 144 VEPSERAAVAMPSLAGPPFGAEAAGSGYPGPLDLRRPMRTVPGPLFTDFVR-PLNINPDR 202
P + A P LA PP A + P L P P L ++ P + P
Sbjct: 616 TPPPQ----APPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 671
Query: 203 ALGPEYPGGSSMHPYCPFPLGYLDAPPGV---PLQQGFRHVSRSQYQGGGLV--SEPGGD 257
+ + +S P P APP + PLQ + P
Sbjct: 672 PVQAPFSPPASP-PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL 730
Query: 258 FQPSYYLPPPPPPLPPLPPLPPQPQFLPPGYLSALHFLPPPP---PPPPPSSFSLTVLFD 314
P +PP PP PP+ P P +PP L PP PP PP+S ++ L
Sbjct: 731 AAPPLQVPPSPPASPPMSPSATPPPRVPP-------LLAAPPLQVPPSPPASLPMSPLAK 783
Query: 315 TDKENTDDQDAEVLSGEPSQPSS 337
+ L PS P+S
Sbjct: 784 PPPQAPPALATPPLQALPSPPAS 806
Score = 46.2 bits (108), Expect = 4e-05
Identities = 77/295 (26%), Positives = 95/295 (32%), Gaps = 71/295 (24%)
Query: 73 GPKQASGAAAAAPAPVPV---------PAASLRP---LSPGTPSGDADPGPEGR------ 114
GP +++G ++ PA P PA + P SPG SG PGP G+
Sbjct: 78 GPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 137
Query: 115 -----AAACFFEQPPRG----------RNPGPRALQPVLGGRSHVEPSE-------RAAV 152
A E P R P P P + RS +E +A
Sbjct: 138 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR 197
Query: 153 AMPSLAGPPFGAEAA---GSGYPGPLDLRRPMRTVPGPLFTDFVRPLNINPDRALGPEYP 209
P GP +A + P P RRP + G L R L+ + P
Sbjct: 198 PRPPTEGPRKSVSSASEHSTTEPSPAARRRP--SAGGGLQRPASRSLSSSATPLSSPARS 255
Query: 210 GGSS-------MHPYCPFPLGY------------LDAPPGV-PLQQGFRHVSRSQYQGGG 249
G S+ HP P P G DA P + PL
Sbjct: 256 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKAR 315
Query: 250 LVSEPGGDFQP-SYYLPPPPPPLPPLPPLPPQPQFLPPGYLSALHFLPPPPPPPP 303
V P P LPP PP PLP PP P P +L LP PP PP
Sbjct: 316 PVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPP-----SLQTLPSPPATPP 365
Score = 37.4 bits (85), Expect = 0.020
Identities = 68/277 (24%), Positives = 86/277 (31%), Gaps = 72/277 (25%)
Query: 74 PKQASGAAAAAPAPVPVPAASLRPLSPGTPSGDADPG---PEGRAAACFFEQPP------ 124
P A+ A P+P P+ P P TP A P P +A PP
Sbjct: 335 PPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHS 394
Query: 125 -----RGRNPGPRALQPVLGGRSHVEPSERAAVAM---------PSLAGPPFGAEAAGSG 170
P P AL + S P+ +A + SL P A
Sbjct: 395 LTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDS 454
Query: 171 YP--GPLDLRR--PMRTVPGPLFTDFVRPLNINPDRALGPEYPGGSSMHPYCP-FPLGYL 225
P PL L P++T P + PL I+P +AL SS+ + P PL L
Sbjct: 455 PPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQAL-------SSLASHSPQAPLSSL 507
Query: 226 DAPPGVPLQQGFRHVSRSQYQGGGLVSEPGGDFQPSYYLPPPP---PPLPPLPPLPPQPQ 282
PP + PS PP PPL LP L P P
Sbjct: 508 IMPP---------------------LETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL 546
Query: 283 FLPPGYLSALHFLPPPPPP-------------PPPSS 306
L+ H PP P PPP +
Sbjct: 547 QTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPET 583
Score = 28.9 bits (63), Expect = 7.0
Identities = 27/104 (25%), Positives = 30/104 (28%), Gaps = 6/104 (5%)
Query: 72 QGPKQASGAAAAAPAPVPVPAASLRPLSPGTPSGDAD-PGPEGRAAACFFEQPPRGRNPG 130
Q P + P P P P TP D GP A PP R+P
Sbjct: 830 QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS 889
Query: 131 PRALQPVLGGRSHVEPSERAAVAMPSLAGPPFGAEAAGSGYPGP 174
P L G S A L G G E + P P
Sbjct: 890 STLSGPDLAGH-----SSSATSTPEELRGYDSGPEGGAAASPPP 928
>gi|56118221 amyloid beta (A4) precursor protein-binding, family B,
member 1 interacting protein [Homo sapiens]
Length = 666
Score = 57.0 bits (136), Expect = 2e-08
Identities = 33/69 (47%), Positives = 36/69 (52%), Gaps = 13/69 (18%)
Query: 247 GGGLVSEPGGDFQPSYYLPPPPPPL--PPLPPLPPQ-----PQFLPP---GYLSALHFLP 296
GGG + P DF P PPPPPPL P LPP PP P F+PP Y
Sbjct: 542 GGGGLPAPPDDFLPP---PPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSEL 598
Query: 297 PPPPPPPPS 305
PPPPPPPP+
Sbjct: 599 PPPPPPPPA 607
Score = 35.8 bits (81), Expect = 0.057
Identities = 50/170 (29%), Positives = 56/170 (32%), Gaps = 36/170 (21%)
Query: 143 HVEPSERAAVAMPSLAGP--PFGAEAAGSGYPGPLDLRRPMRTVPGPLFTDFVRPLNINP 200
H E S+ A+ + P P A S P P +RR T P PL
Sbjct: 486 HAETSKDKKPALGNHHDPAVPRAPHAPKSSLPPPPPVRRSSDTSGSP-----ATPLKAKG 540
Query: 201 DRALGPEYPGGSSMHPYCPFPLGYLDAPPGVPLQQGFRHVSRSQYQGGGLVSEPGGDF-- 258
G P + P P P LD P P F EP DF
Sbjct: 541 TGGGGLPAPPDDFLPP--PPPPPPLDDPELPPPPPDFM--------------EPPPDFVP 584
Query: 259 --QPSYY------LPPPPPPLPPLPPLPPQPQFLPPGYLSALHFLPPPPP 300
PSY LPPPPPP P P P PP A+ PP PP
Sbjct: 585 PPPPSYAGIAGSELPPPPPPPPAPAPAPVPDSARPP---PAVAKRPPVPP 631
Score = 29.6 bits (65), Expect = 4.1
Identities = 15/40 (37%), Positives = 22/40 (55%), Gaps = 3/40 (7%)
Query: 295 LPPPPPPPPPSSFSLTVLFDTDKEN---TDDQDAEVLSGE 331
LPPP P PP + F+ +V F E+ +DQD + L +
Sbjct: 31 LPPPDPNPPRAEFNYSVGFKDLNESLNALEDQDLDALMAD 70
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 57.0 bits (136), Expect = 2e-08
Identities = 71/246 (28%), Positives = 90/246 (36%), Gaps = 44/246 (17%)
Query: 88 VPVPAASLRPLSPGTPSGDADPGPEGRA------AACFFEQPPRGRNPGPRALQPVLGGR 141
+PVP PL P P A P P A + P+GR+ +Q R
Sbjct: 1 MPVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLR 60
Query: 142 SHVEPSERAAVAMPSLAGPPFGAEAAGSGYPGPLDLRRPMRTVP--GPLFTD---FVRPL 196
+ ++R+A + S G E GS R T P G LF +RP
Sbjct: 61 KVTQINDRSAPQIESSKGT--NKEGGGSANT------RGASTPPTLGDLFAGGFPVLRPA 112
Query: 197 NINPDRALGPEYPGGSSMHPYCPFPLGYLDAPPGVPLQQGFRHVSRSQYQGGGLVSEPGG 256
D A G G S P P + P P R + S+ G + P
Sbjct: 113 G-QRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASP--RLGNTSEAHGAARTAPP-- 167
Query: 257 DFQPSYYLPPPPPPLPPLPPLPP---------QPQFLPPGYLS---------ALHFLPPP 298
+P+ PPPP P PP PPLPP P PPG L+ + PPP
Sbjct: 168 --RPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPP 225
Query: 299 PPPPPP 304
PPPPPP
Sbjct: 226 PPPPPP 231
Score = 53.9 bits (128), Expect = 2e-07
Identities = 71/270 (26%), Positives = 96/270 (35%), Gaps = 37/270 (13%)
Query: 73 GPKQASGAAAAAPAP-VPVPAASLRPLSPGTPSGDADPGPEGRAAACFFEQPPRGRNPGP 131
G K G + AP+P +P S + P +P G A PPR P P
Sbjct: 119 GGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTA----PPRPNVPAP 174
Query: 132 RALQPVLGGRSHVEPSERAAVAMPSLAGPPFGAEAAGS--GYPGPLDLRRPMRTVPGPLF 189
P P ++ L PP G G+ P+ P P P
Sbjct: 175 PPPTPPPPPPPLPPPLPSSSPIKTPLVSPP-GPLTKGNLPVVAPPVPCAPPPPPPPPPPT 233
Query: 190 TDFVRPLNINPDRALGPEYPGGSSMH-PYCPFPLGYLDAPPGVPLQQGFRHVSRSQYQGG 248
+ P ++ D+A+ P+ + +H P P PL L P G P
Sbjct: 234 PPPLPPASVLSDKAVKPQL---APLHLPPIPPPLPLLP-PCGYP---------------- 273
Query: 249 GLVSEPGGDFQPSYYLPPPPPPLPPLPPLPPQPQFLPPGYLSALHFLPPPPPPPPPSSFS 308
GL +EP Q + P PPPPLPP P+ LP L ++ PPP PP S S
Sbjct: 274 GLKAEPASPAQDAQEPPAPPPPLPPYASCSPRAS-LPAPPLPGVNSSSETPPPLPPKSPS 332
Query: 309 LTVLFDTDKENTDDQDAEVLSGEPSQPSSQ 338
+ A+ L P+ P SQ
Sbjct: 333 F-------QAPPQKAGAQALPAPPAPPGSQ 355
Score = 47.4 bits (111), Expect = 2e-05
Identities = 62/204 (30%), Positives = 73/204 (35%), Gaps = 42/204 (20%)
Query: 125 RGRNPGPRALQPVLGGRSHVEPSERAAVAMPSLAGPPFGAEAAGSGYPGPLDLRRPMRTV 184
RG + P GG + P+ + VA P GS P P R P +T+
Sbjct: 90 RGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGP------GSRAPSP---RLPNKTI 140
Query: 185 PGPLFTDFVRPLNINPDRALGPEYPGGSSMHPYCPFPLGYLDAPPGVPLQQGFRHVSRSQ 244
GPL P N A G + P P P PP PL S +
Sbjct: 141 SGPLIPP-ASPRLGNTSEAHGAART--APPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIK 197
Query: 245 YQGGGLVSEPG----GDFQ------PSYYLPPPPPPLPPLPPLPP---------QPQFLP 285
LVS PG G+ P PPPPPP P PPLPP +PQ P
Sbjct: 198 TP---LVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAP 254
Query: 286 PGYLSALHFLPPPPPPP--PPSSF 307
LH P PPP P PP +
Sbjct: 255 ------LHLPPIPPPLPLLPPCGY 272
Score = 45.4 bits (106), Expect = 7e-05
Identities = 26/67 (38%), Positives = 31/67 (46%), Gaps = 11/67 (16%)
Query: 264 LPPPPPPLPPLPPLPPQPQFLPPGYLSALHFLPPPPPPPPPSSFSLTVLFDTDKENTDDQ 323
+P PPPP PPLPP PP P P PPPPP PP S + L D +
Sbjct: 1 MPVPPPPPPPLPP-PPPPLGAP----------PPPPPSAPPVSTDTSSLRRADPKGRSAL 49
Query: 324 DAEVLSG 330
A++ G
Sbjct: 50 LADIQQG 56
>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
Length = 638
Score = 56.6 bits (135), Expect = 3e-08
Identities = 73/263 (27%), Positives = 95/263 (36%), Gaps = 50/263 (19%)
Query: 89 PVPAASLRPLSPGTPSGDADPGPEGRAAACFFEQPPRGRNPGPRALQPVLGGRSHVEPSE 148
PVPA+ P T + P P A NP P +L R S
Sbjct: 324 PVPASVGSTSGPATTPLASAPRPAAPA-----------NNPPPPSLMSTTQSRPPWMNSG 372
Query: 149 RAAVAMPSLAGPPFGAEAAGSGYPG--PLDLRRPMRTVPGPLFTDFVRPLNINPDRALGP 206
PS + P G G G PG P P+ ++ G P+ NP+ GP
Sbjct: 373 ------PSESRPYHGMHGGGPGGPGGGPHSFPHPLPSLTGG---HGGHPMQHNPN---GP 420
Query: 207 EYPGGSSMHPYC---PFPLGYLDAPP------GVPLQQGFRHVSRSQYQGGGLVSEPGGD 257
P P P P G+ PP P+ G + +QG G++ P
Sbjct: 421 PPPWMQPPPPPMNQGPHPPGHHGPPPMDQYLGSTPVGSGVYRL----HQGKGMMPPP--- 473
Query: 258 FQPSYYLPPPPPPLPPLPPLPPQPQFLPPGYLSALHFLPPPPPPPPPSSFSLTVLFDTDK 317
P +PPPPPP P P PP LPP PPPPPPP SS + + +
Sbjct: 474 --PMGMMPPPPPP-PSGQPPPPPSGPLPPWQQQQQQ---PPPPPPPSSSMASSTPLPWQQ 527
Query: 318 ENTDDQDAEVLSGEPSQPSSQEQ 340
T + +G S P Q+Q
Sbjct: 528 NTTTTTTS---AGTGSIPPWQQQ 547
Score = 44.3 bits (103), Expect = 2e-04
Identities = 63/240 (26%), Positives = 81/240 (33%), Gaps = 37/240 (15%)
Query: 79 GAAAAAPAPVPVPAASLRPLSPGTPSGDADPGPEGRAAACFFEQPPRGRNPGPRALQPVL 138
G P P P SL G P GP + + PP N GP
Sbjct: 388 GGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPP----WMQPPPPPMNQGPHP----- 438
Query: 139 GGRSHVEPSERAAVAMPSLAGPPFGAEAAGSGYPGPLDLRRPMRTVPGPLFTDFVRPLNI 198
G P ++ + P +G + G P P+ + P P P P
Sbjct: 439 PGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPP---PPP-------PSGQ 488
Query: 199 NPDRALGPEYPGGSSMH--PYCPFPLGYLDAPPGVPLQQGFRHVSRSQYQGGGLVSEPGG 256
P GP P P P P + + +P QQ + S G P
Sbjct: 489 PPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGS---IPPWQ 545
Query: 257 DFQPSYYLPPPPPPL---PPLPPLPP--QPQFLPPGYLSALHFLPPPPPPPPPSSFSLTV 311
Q + P P + P + PLPP QP LPPG PPPPPPPPP S + +
Sbjct: 546 QQQAAAAASPGAPQMQGNPTMVPLPPGVQPP-LPPG-------APPPPPPPPPGSAGMMI 597
Score = 29.3 bits (64), Expect = 5.3
Identities = 21/60 (35%), Positives = 23/60 (38%), Gaps = 13/60 (21%)
Query: 227 APPGVPLQQGFRHVSRSQYQGGGLVSEPGGDFQPSYYLPPPPPPLPPLPPLPPQPQFLPP 286
A PG P QG +V P G P LPP PP PP PP +PP
Sbjct: 553 ASPGAPQMQG----------NPTMVPLPPGVQPP---LPPGAPPPPPPPPPGSAGMMIPP 599
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.137 0.440
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,865,247
Number of Sequences: 37866
Number of extensions: 1928572
Number of successful extensions: 36471
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 755
Number of HSP's successfully gapped in prelim test: 1229
Number of HSP's that attempted gapping in prelim test: 12542
Number of HSP's gapped (non-prelim): 11557
length of query: 342
length of database: 18,247,518
effective HSP length: 103
effective length of query: 239
effective length of database: 14,347,320
effective search space: 3429009480
effective search space used: 3429009480
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.