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Search of human proteins with 24307887
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24307887 one cut homeobox 1 [Homo sapiens]
(465 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24307887 one cut homeobox 1 [Homo sapiens] 972 0.0
gi|119220564 one cut domain, family member 2 [Homo sapiens] 555 e-158
gi|122937424 one cut homeobox 3 [Homo sapiens] 434 e-121
gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens] 78 1e-14
gi|116517292 cut-like 2 [Homo sapiens] 77 3e-14
gi|110347455 Brn3b POU domain transcription factor [Homo sapiens] 55 2e-07
gi|148762982 hypothetical protein LOC387640 [Homo sapiens] 50 4e-06
gi|28893581 LIM homeobox transcription factor 1, alpha isoform a... 49 7e-06
gi|5031761 homeobox A1 isoform a [Homo sapiens] 49 7e-06
gi|239757043 PREDICTED: functional smad suppressing element 18 [... 49 1e-05
gi|239751555 PREDICTED: functional smad suppressing element 18 [... 49 1e-05
gi|239746067 PREDICTED: functional smad suppressing element 18 [... 49 1e-05
gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regula... 48 2e-05
gi|18765758 dual-specificity tyrosine-(Y)-phosphorylation regula... 48 2e-05
gi|7710129 LIM domain only 6 [Homo sapiens] 48 2e-05
gi|114326455 chromodomain helicase DNA binding protein 8 [Homo s... 48 2e-05
gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens] 48 2e-05
gi|14916427 naked cuticle homolog 2 [Homo sapiens] 47 3e-05
gi|27894361 nuclear receptor subfamily 4, group A, member 3 isof... 47 4e-05
gi|27894359 nuclear receptor subfamily 4, group A, member 3 isof... 47 4e-05
gi|27894357 nuclear receptor subfamily 4, group A, member 3 isof... 47 4e-05
gi|27894355 nuclear receptor subfamily 4, group A, member 3 isof... 47 4e-05
gi|4505965 POU class 4 homeobox 3 [Homo sapiens] 47 5e-05
gi|122937233 discs, large (Drosophila) homolog-associated protei... 46 6e-05
gi|55770830 chromobox homolog 4 [Homo sapiens] 46 8e-05
gi|4507973 zinc finger protein of the cerebellum 3 [Homo sapiens] 46 8e-05
gi|4505007 LIM homeobox transcription factor 1, beta [Homo sapiens] 45 1e-04
gi|196114999 special AT-rich sequence binding protein 1 [Homo sa... 45 1e-04
gi|4506791 special AT-rich sequence binding protein 1 [Homo sapi... 45 1e-04
gi|33859670 leucine-rich repeats and calponin homology (CH) doma... 45 1e-04
>gi|24307887 one cut homeobox 1 [Homo sapiens]
Length = 465
Score = 972 bits (2513), Expect = 0.0
Identities = 465/465 (100%), Positives = 465/465 (100%)
Query: 1 MNAQLTMEAIGELHGVSHEPVPAPADLLGGSPHARSSVAHRGSHLPPAHPRSMGMASLLD 60
MNAQLTMEAIGELHGVSHEPVPAPADLLGGSPHARSSVAHRGSHLPPAHPRSMGMASLLD
Sbjct: 1 MNAQLTMEAIGELHGVSHEPVPAPADLLGGSPHARSSVAHRGSHLPPAHPRSMGMASLLD 60
Query: 61 GGSGGGDYHHHHRAPEHSLAGPLHPTMTMACETPPGMSMPTTYTTLTPLQPLPPISTVSD 120
GGSGGGDYHHHHRAPEHSLAGPLHPTMTMACETPPGMSMPTTYTTLTPLQPLPPISTVSD
Sbjct: 61 GGSGGGDYHHHHRAPEHSLAGPLHPTMTMACETPPGMSMPTTYTTLTPLQPLPPISTVSD 120
Query: 121 KFPHHHHHHHHHHHPHHHQRLAGNVSGSFTLMRDERGLASMNNLYTPYHKDVAGMGQSLS 180
KFPHHHHHHHHHHHPHHHQRLAGNVSGSFTLMRDERGLASMNNLYTPYHKDVAGMGQSLS
Sbjct: 121 KFPHHHHHHHHHHHPHHHQRLAGNVSGSFTLMRDERGLASMNNLYTPYHKDVAGMGQSLS 180
Query: 181 PLSSSGLGSIHNSQQGLPHYAHPGAAMPTDKMLTPNGFEAHHPAMLGRHGEQHLTPTSAG 240
PLSSSGLGSIHNSQQGLPHYAHPGAAMPTDKMLTPNGFEAHHPAMLGRHGEQHLTPTSAG
Sbjct: 181 PLSSSGLGSIHNSQQGLPHYAHPGAAMPTDKMLTPNGFEAHHPAMLGRHGEQHLTPTSAG 240
Query: 241 MVPINGLPPHHPHAHLNAQGHGQLLGTAREPNPSVTGAQVSNGSNSGQMEEINTKEVAQR 300
MVPINGLPPHHPHAHLNAQGHGQLLGTAREPNPSVTGAQVSNGSNSGQMEEINTKEVAQR
Sbjct: 241 MVPINGLPPHHPHAHLNAQGHGQLLGTAREPNPSVTGAQVSNGSNSGQMEEINTKEVAQR 300
Query: 301 ITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQ 360
ITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQ
Sbjct: 301 ITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQ 360
Query: 361 RMSALRLAACKRKEQEHGKDRGNTPKKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQ 420
RMSALRLAACKRKEQEHGKDRGNTPKKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQ
Sbjct: 361 RMSALRLAACKRKEQEHGKDRGNTPKKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQ 420
Query: 421 QLGLELSTVSNFFMNARRRSLDKWQDEGSSNSGNSSSSSSTCTKA 465
QLGLELSTVSNFFMNARRRSLDKWQDEGSSNSGNSSSSSSTCTKA
Sbjct: 421 QLGLELSTVSNFFMNARRRSLDKWQDEGSSNSGNSSSSSSTCTKA 465
>gi|119220564 one cut domain, family member 2 [Homo sapiens]
Length = 504
Score = 555 bits (1431), Expect = e-158
Identities = 324/513 (63%), Positives = 366/513 (71%), Gaps = 76/513 (14%)
Query: 1 MNAQLTMEAIGELHGVSHE----------------PVPAPADLLGGSPHARSSVAH---R 41
MN +LTME++G LHG + P L SPH A R
Sbjct: 20 MNPELTMESLGTLHGPAGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLR 79
Query: 42 GSHLPPAHPRSMG-----------------MASLLDGGSGGGDYHHHHRAPEHSLAGPLH 84
G PP + +G MAS+LDGG DY PE S+ PLH
Sbjct: 80 GPPPPPTAHQELGTAAAAAAAASRSAMVTSMASILDGG----DYR-----PELSI--PLH 128
Query: 85 PTMTMACET-PPGMSMPTTYTTLTPLQPLPPISTVSDKFPHHHHHHH-HHHHPHHHQRLA 142
M+M+C++ PPGM M TYTTLTPLQPLPPISTVSDKF H H HHH HHHH HHHQRL+
Sbjct: 129 HAMSMSCDSSPPGMGMSNTYTTLTPLQPLPPISTVSDKFHHPHPHHHPHHHHHHHHQRLS 188
Query: 143 GNVSGSFTLMRDERGLASMNNLYTPYHKDVAGMGQSLSPLSSS----GLGSIHNSQQGLP 198
GNVSGSFTLMRDERGL +MNNLY+PY K++ GM QSLSPL+++ GLG +HN+QQ LP
Sbjct: 189 GNVSGSFTLMRDERGLPAMNNLYSPY-KEMPGMSQSLSPLAATPLGNGLGGLHNAQQSLP 247
Query: 199 HYAHPGAAMPTDKMLTPNGFEAHHPAMLGRHGEQHL-----TPTSAGMVPINGLPPHHPH 253
+Y PG DKML+PN F+AHH AML R GEQHL TP +A M +NGL HHP
Sbjct: 248 NYGPPGH----DKMLSPN-FDAHHTAMLTR-GEQHLSRGLGTPPAAMMSHLNGL--HHPG 299
Query: 254 AHLNAQGHGQLLGTARE-PNPSVTGAQVSNGSNSGQMEEINTKEVAQRITTELKRYSIPQ 312
+ Q HG +L +RE P S +G+QV+ SGQ+EEINTKEVAQRIT ELKRYSIPQ
Sbjct: 300 ---HTQSHGPVLAPSRERPPSSSSGSQVAT---SGQLEEINTKEVAQRITAELKRYSIPQ 353
Query: 313 AIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKR 372
AIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKR
Sbjct: 354 AIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKR 413
Query: 373 KEQEHGKDRGNTPKKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQQLGLELSTVSNF 432
KEQE KDR N+ KK RLVFTD+QRRTL AIFKENKRPSKE+QITISQQLGLEL+TVSNF
Sbjct: 414 KEQEPNKDRNNSQKKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELTTVSNF 473
Query: 433 FMNARRRSLDKWQDEGSSNSGNSSSSSSTCTKA 465
FMNARRRSL+KWQD+ S +G SSS+SSTCTKA
Sbjct: 474 FMNARRRSLEKWQDDLS--TGGSSSTSSTCTKA 504
>gi|122937424 one cut homeobox 3 [Homo sapiens]
Length = 494
Score = 434 bits (1115), Expect = e-121
Identities = 272/504 (53%), Positives = 313/504 (62%), Gaps = 53/504 (10%)
Query: 4 QLTMEAIGELHGVSHEPVPAPADLLGGSPHARSSVA-HRGSHLPPAHPRSMGMASLLDGG 62
+L++E++G LH V+H A A L HARS+ A HRG P GMASLLDGG
Sbjct: 2 ELSLESLGGLHSVAH----AQAGELLSPGHARSAAAQHRGLVAPGRPGLVAGMASLLDGG 57
Query: 63 SGGGDYHHHHRAPEHS----------LAGPLHPTMTMACETPPGMSMPTTYTTLTPLQPL 112
GGG S LAGPLHP M MACE P + TYTTLTPLQ L
Sbjct: 58 GGGGGGGAGGAGGAGSAGGGADFRGELAGPLHPAMGMACEAP---GLGGTYTTLTPLQHL 114
Query: 113 PPISTVSDKFPHHH--------HHHHHHHHPHHH---------QRLAGNVSGSFTLMRDE 155
PP++ V+DKF H H H H HPH QRLA +VSGSFTLMRDE
Sbjct: 115 PPLAAVADKFHQHAAAAAVAGAHGGHPHAHPHPAAAPPPPPPPQRLAASVSGSFTLMRDE 174
Query: 156 RG-LASMNNLYTPYHKDVAGMGQSLSPLSSSGLGSIHNSQQGLPH--------YAHPGAA 206
R LAS+ +LY PY K++ MG LSPL ++ ++H + Q P Y PG
Sbjct: 175 RAALASVGHLYGPYGKELPAMGSPLSPLPNALPPALHGAPQPPPPPPPPPLAAYGPPGH- 233
Query: 207 MPTDKMLTPNGFEAHHPAMLGRHGEQHLT---PTSAGMVPINGLPPHHPHAHLNAQGHGQ 263
+ DK+L P FE H A+LGR E L P G G L G G
Sbjct: 234 LAGDKLLPPAAFEPH-AALLGR-AEDALARGLPGGGGGTGSGGAGSGSAAGLLAPLG-GL 290
Query: 264 LLGTAREPNPSVTGAQVSNGSNSG--QMEEINTKEVAQRITTELKRYSIPQAIFAQRVLC 321
A P+ G S G S EEINTKEVAQRIT ELKRYSIPQAIFAQR+LC
Sbjct: 291 AAAGAHGPHGGGGGPGGSGGGPSAGAAAEEINTKEVAQRITAELKRYSIPQAIFAQRILC 350
Query: 322 RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRKEQEHGKDR 381
RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRKEQE K+R
Sbjct: 351 RSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRKEQEQQKER 410
Query: 382 GNTPKKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQQLGLELSTVSNFFMNARRRSL 441
PKK RLVFTD+QRRTL AIFKENKRPSKE+Q+TISQQLGLEL+TVSNFFMNARRR +
Sbjct: 411 ALQPKKQRLVFTDLQRRTLIAIFKENKRPSKEMQVTISQQLGLELNTVSNFFMNARRRCM 470
Query: 442 DKWQDEGSSNSGNSSSSSSTCTKA 465
++W +E S+ G + +++T +KA
Sbjct: 471 NRWAEEPSTAPGGPAGATATFSKA 494
>gi|148277064 cut-like homeobox 1 isoform a [Homo sapiens]
Length = 1505
Score = 78.2 bits (191), Expect = 1e-14
Identities = 58/205 (28%), Positives = 95/205 (46%), Gaps = 30/205 (14%)
Query: 291 EINTKEVAQRITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLK-SGRETFRR 349
E++T + +R+ L ++ Q +F + +L +QG++SDLL PKPW KL GRE F R
Sbjct: 1125 ELDTYGITKRVKEVLTDNNLGQRLFGETILGLTQGSVSDLLARPKPWHKLSLKGREPFVR 1184
Query: 350 MWKWLQEP----EFQRMSALRLAACKRKEQEHGKD--------------RGNTP------ 385
M WL +P + M + A ++ D +G +P
Sbjct: 1185 MQLWLNDPNNVEKLMDMKRMEKKAYMKRRHSSVSDSQPCEPPSVGTEYSQGASPQPQHQL 1244
Query: 386 KKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQQLGLELSTVSNFFMNARRR-----S 440
KKPR+V ++ L +++ PS + ++ QL L+ STV N+F N R R
Sbjct: 1245 KKPRVVLAPEEKEALKRAYQQKPYPSPKTIEDLATQLNLKTSTVINWFHNYRSRIRRELF 1304
Query: 441 LDKWQDEGSSNSGNSSSSSSTCTKA 465
+++ Q +G S S S+ +A
Sbjct: 1305 IEEIQAGSQGQAGASDSPSARSGRA 1329
Score = 69.7 bits (169), Expect = 5e-12
Identities = 57/200 (28%), Positives = 97/200 (48%), Gaps = 32/200 (16%)
Query: 266 GTAREPNPSVTGAQVSNGSNSGQMEEINTKEVAQRITTELKRYSIPQAIFAQRVLCRSQG 325
G A P+ S + VS G EE++T E+A+++ +L +++I Q IF VL SQG
Sbjct: 531 GMAPSPSQSESAGSVSEG------EEMDTAEIARQVKEQLIKHNIGQRIFGHYVLGLSQG 584
Query: 326 TLSDLLRNPKPWSKLK-SGRETFRRMWKWLQEPEFQRMSALRLAACKRKEQEHGKDRGNT 384
++S++L PKPW+KL G+E F +M ++L + Q + ALR G+ R N
Sbjct: 585 SVSEILARPKPWNKLTVRGKEPFHKMKQFLSDE--QNILALR--------SIQGRQRENP 634
Query: 385 PKKPRLVFTDVQRR------TLHAIFKENKRPSKELQITISQQLGLELSTVSNFFMNARR 438
+ +F +V +R + + ++ S E +I +Q EL +
Sbjct: 635 GQSLNRLFQEVPKRRNGSEGNITTRIRASETGSDEAIKSILEQAKRELQV---------Q 685
Query: 439 RSLDKWQDEGSSNSGNSSSS 458
++ + Q +S SGNS +
Sbjct: 686 KTAEPAQPSSASGSGNSDDA 705
Score = 62.8 bits (151), Expect = 6e-10
Identities = 31/66 (46%), Positives = 46/66 (69%), Gaps = 1/66 (1%)
Query: 290 EEINTKEVAQRITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKL-KSGRETFR 348
+E++T E+ +++ +L + I Q IF ++VL SQG++SD+L PKPWSKL + GRE F
Sbjct: 941 QEVDTIELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFI 1000
Query: 349 RMWKWL 354
RM WL
Sbjct: 1001 RMQLWL 1006
>gi|116517292 cut-like 2 [Homo sapiens]
Length = 1486
Score = 77.4 bits (189), Expect = 3e-14
Identities = 62/213 (29%), Positives = 98/213 (46%), Gaps = 35/213 (16%)
Query: 274 SVTGAQVSNGSNSGQMEEI-------NTKEVAQRITTELKRYSIPQAIFAQRVLCRSQGT 326
S++G S G ++EI +T + +R+ L ++ Q +F + +L +QG+
Sbjct: 1022 SLSGKMYSGSQAPGGIQEIVAMSPELDTYSITKRVKEVLTDNNLGQRLFGESILGLTQGS 1081
Query: 327 LSDLLRNPKPWSKLK-SGRETFRRMWKWLQEP----EFQRMSAL-RLAACKRK------- 373
+SDLL PKPW KL GRE F RM WL +P + + M L + A KR+
Sbjct: 1082 VSDLLSRPKPWHKLSLKGREPFVRMQLWLNDPHNVEKLRDMKKLEKKAYLKRRYGLISTG 1141
Query: 374 -EQEHGKDRGNTP--------------KKPRLVFTDVQRRTLHAIFKENKRPSKELQITI 418
+ E R P KKPR+V ++ L ++ PS++ +
Sbjct: 1142 SDSESPATRSECPSPCLQPQDLSLLQIKKPRVVLAPEEKEALRKAYQLEPYPSQQTIELL 1201
Query: 419 SQQLGLELSTVSNFFMNARRRSLDKWQDEGSSN 451
S QL L+ +TV N+F N R R + EG+ +
Sbjct: 1202 SFQLNLKTNTVINWFHNYRSRMRREMLVEGTQD 1234
Score = 63.2 bits (152), Expect = 5e-10
Identities = 31/67 (46%), Positives = 46/67 (68%), Gaps = 1/67 (1%)
Query: 291 EINTKEVAQRITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKL-KSGRETFRR 349
E++T E+ +++ +L + I Q IF ++VL SQG++SD+L PKPWSKL + GRE F R
Sbjct: 895 EVDTLELTRQVKEKLAKNGICQRIFGEKVLGLSQGSVSDMLSRPKPWSKLTQKGREPFIR 954
Query: 350 MWKWLQE 356
M WL +
Sbjct: 955 MQLWLSD 961
Score = 58.2 bits (139), Expect = 2e-08
Identities = 45/151 (29%), Positives = 78/151 (51%), Gaps = 11/151 (7%)
Query: 230 GEQHLTPTSAGMVPINGLPPHHPHAHLNAQGHGQLLGTAREPNPSVTGAQVSNGSNSG-- 287
GE+ + P +A GL P A A+ A P P + G + ++G G
Sbjct: 487 GERLMMPPAAFKGEAGGLLVFPP-AFYGAKPPTAPATPAPGPEP-LGGPEPADGGGGGAA 544
Query: 288 ----QMEEINTKEVAQRITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLK-S 342
+ E+++T E+A ++ +L +++I Q +F VL SQG++S++L PKPW KL
Sbjct: 545 GPGAEEEQLDTAEIAFQVKEQLLKHNIGQRVFGHYVLGLSQGSVSEILARPKPWRKLTVK 604
Query: 343 GRETFRRMWKWLQEPEFQRMSALRLAACKRK 373
G+E F +M ++L + Q + ALR +++
Sbjct: 605 GKEPFIKMKQFLSDE--QNVLALRTIQVRQR 633
>gi|110347455 Brn3b POU domain transcription factor [Homo sapiens]
Length = 409
Score = 54.7 bits (130), Expect = 2e-07
Identities = 49/178 (27%), Positives = 68/178 (38%), Gaps = 20/178 (11%)
Query: 70 HHHRAPEHSLAGPLHPTMTMACETPPGMSMPTTYTTLTPLQPLPPISTVSDKFPHHHHHH 129
HHH P HS P P T ++P T + P+ S ++ HHHHHH
Sbjct: 126 HHHHPPHHS---PFKPDATYHTMN----TIPCTSAASSSSVPISHPSALAGT--HHHHHH 176
Query: 130 HHHHHPHHHQRLAGNVSGSFTLMRDERGLASMNN--LYTPYHKDVAGMGQSLSPLSSSGL 187
HHHHH HQ L G + + +A + + TP H A +++P+ + L
Sbjct: 177 HHHHHHQPHQALEGELLEHLSPGLALGAMAGPDGAVVSTPAH---APHMATMNPMHQAAL 233
Query: 188 GSIHNSQQGLPHYAHPGAAMPTDKMLTPNGFEAHHPAMLGRHGEQHLTPTSAGMVPIN 245
H GLP +H G D P EA R + +T G N
Sbjct: 234 SMAH--AHGLP--SHMGCMSDVD--ADPRDLEAFAERFKQRRIKLGVTQADVGSALAN 285
Score = 48.5 bits (114), Expect = 1e-05
Identities = 99/453 (21%), Positives = 153/453 (33%), Gaps = 84/453 (18%)
Query: 8 EAIGELHGVSHEPVPAPADLLGGSPHARSSVAHRGSHLPPAHPRSMGMASLLDGGSGGGD 67
+A HG S P + L SP + + +A S P+ + G GG GGG
Sbjct: 10 QAFSMPHGGSLHVEPKYSALHSTSPGSSAPIAPSASS--PSSSSNAGGGGGGGGGGGGGG 67
Query: 68 YHHHHRAPEHSLAGPLHPTMTMAC-ETPPGMSMP-TTYTTLTPLQPLPPISTVSDKFPHH 125
+ S G M AC TPP + L + L + VS HH
Sbjct: 68 GRSSSSSSSGSSGGGGSEAMRRACLPTPPSNIFGGLDESLLARAEALAAVDIVSQSKSHH 127
Query: 126 HHHHHHHHHPHHHQRLAGNVSGSFTLMRDERGLASMNNLYTPYHKDVAGMGQSLSPLSSS 185
HH HH +P+ D + P +S+
Sbjct: 128 HHPPHH----------------------------------SPFKPDATYHTMNTIPCTSA 153
Query: 186 GLGSIHNSQQGLPHYAHPGAAMPTDKMLTPNGFEAHHPAMLGRHGE--QHLTPTSA--GM 241
S +P +HP A T + H P GE +HL+P A M
Sbjct: 154 A------SSSSVP-ISHPSALAGTHHHHHHHHHHHHQPHQ-ALEGELLEHLSPGLALGAM 205
Query: 242 VPINGL----PPHHPH-AHLNAQGHGQLLGTAREPNPSVTGAQVSNGSNSGQMEEINTKE 296
+G P H PH A +N L PS G ++ +E +
Sbjct: 206 AGPDGAVVSTPAHAPHMATMNPMHQAALSMAHAHGLPSHMGCMSDVDADPRDLEAFAERF 265
Query: 297 VAQRITTELKRYSIPQAI----------FAQRVLCRSQGTLSDLLRNPKPWSKLKSGRET 346
+RI + + + A+ +Q +CR + L + LK +
Sbjct: 266 KQRRIKLGVTQADVGSALANLKIPGVGSLSQSTICRFES----LTLSHNNMIALKPILQA 321
Query: 347 FRRMWKWLQEPEFQRMSALRLAACKRKEQEHGKDRGNTPKKPRLVFTDVQRRTLHAIFKE 406
WL+E E L + E +G ++ K+ R ++R+L A F
Sbjct: 322 ------WLEEAEKSHREKLT-----KPELFNGAEK----KRKRTSIAAPEKRSLEAYFAI 366
Query: 407 NKRPSKELQITISQQLGLELSTVSNFFMNARRR 439
RPS E I+++L L+ + V +F N R++
Sbjct: 367 QPRPSSEKIAAIAEKLDLKKNVVRVWFCNQRQK 399
>gi|148762982 hypothetical protein LOC387640 [Homo sapiens]
Length = 908
Score = 50.1 bits (118), Expect = 4e-06
Identities = 15/17 (88%), Positives = 16/17 (94%)
Query: 123 PHHHHHHHHHHHPHHHQ 139
PHHHHHHHHHHH HHH+
Sbjct: 336 PHHHHHHHHHHHHHHHR 352
Score = 47.8 bits (112), Expect = 2e-05
Identities = 15/18 (83%), Positives = 15/18 (83%)
Query: 123 PHHHHHHHHHHHPHHHQR 140
P HHHHHHHHHH HHH R
Sbjct: 335 PPHHHHHHHHHHHHHHHR 352
Score = 44.7 bits (104), Expect = 2e-04
Identities = 28/85 (32%), Positives = 41/85 (48%), Gaps = 17/85 (20%)
Query: 124 HHHHHHHHHHHPH------------HHQRLAGNVSGSFTLMRDERGLASMNNLYTPYHKD 171
HHHHHHHHHHH H HH R ++ GSF + S ++ Y+ + +
Sbjct: 339 HHHHHHHHHHHHHRAQPPQQSHHPPHHHRPQPHL-GSFP---ESCSSDSESSSYSDHAAN 394
Query: 172 VAGMGQSLSPLSSSGLGSIHNSQQG 196
+ G SLS SS+ + S ++G
Sbjct: 395 DSDFGSSLSS-SSNSVSSEEEEEEG 418
Score = 42.7 bits (99), Expect = 7e-04
Identities = 14/20 (70%), Positives = 14/20 (70%)
Query: 123 PHHHHHHHHHHHPHHHQRLA 142
P HHHHHHHHH HHH A
Sbjct: 334 PPPHHHHHHHHHHHHHHHRA 353
>gi|28893581 LIM homeobox transcription factor 1, alpha isoform a
[Homo sapiens]
Length = 382
Score = 49.3 bits (116), Expect = 7e-06
Identities = 28/90 (31%), Positives = 48/90 (53%), Gaps = 3/90 (3%)
Query: 376 EHGKDRGNTPKKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQQLGLELSTVSNFFMN 435
E GKD PK+PR + T QRR A F+ + +P ++++ T++ + GL + V +F N
Sbjct: 187 EEGKDH-KRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQN 245
Query: 436 --ARRRSLDKWQDEGSSNSGNSSSSSSTCT 463
A+ + L + Q + + N+ SS T
Sbjct: 246 QRAKMKKLARRQQQQQQDQQNTQRLSSAQT 275
>gi|5031761 homeobox A1 isoform a [Homo sapiens]
Length = 335
Score = 49.3 bits (116), Expect = 7e-06
Identities = 36/123 (29%), Positives = 53/123 (43%), Gaps = 7/123 (5%)
Query: 123 PHHHHHHHHHHHPHHHQRLAGN--VSGSFTLMRDERGLASMNNLYTPY----HKDVAGMG 176
PHHHHHHHHHH + +GN VS S + G + + Y+PY DV+G
Sbjct: 64 PHHHHHHHHHHPQPATYQTSGNLGVSYSHSSCGPSYGSQNFSAPYSPYALNQEADVSGGY 123
Query: 177 QSLSPLSSSGLGSIHNSQQGLPHYAHPGAAMPTDKMLTPNGFEAHHPAMLGRHGEQHLTP 236
+P SG S Q H + G A+ + + + + + H L + L+P
Sbjct: 124 PQCAPAVYSGNLSSPMVQHHHHHQGYAGGAVGSPQYIHHSYGQEHQSLALATYNNS-LSP 182
Query: 237 TSA 239
A
Sbjct: 183 LHA 185
Score = 34.7 bits (78), Expect = 0.19
Identities = 33/131 (25%), Positives = 48/131 (36%), Gaps = 31/131 (23%)
Query: 62 GSGGGDYHHHHRAPE---------------HSLAGPLHPTMTMACE-TPPGMSMPTTYTT 105
GS +HHHH P+ HS GP + + + +P ++ +
Sbjct: 62 GSPHHHHHHHHHHPQPATYQTSGNLGVSYSHSSCGPSYGSQNFSAPYSPYALNQEADVSG 121
Query: 106 LTPLQPLPPISTVSDKFPHHHHHHHHHHHPHHHQRLAGNVSGSFTLMRDERG-------L 158
P Q P + + + P HH HHHQ AG GS + G L
Sbjct: 122 GYP-QCAPAVYSGNLSSPMVQHH-------HHHQGYAGGAVGSPQYIHHSYGQEHQSLAL 173
Query: 159 ASMNNLYTPYH 169
A+ NN +P H
Sbjct: 174 ATYNNSLSPLH 184
>gi|239757043 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 996
Score = 48.9 bits (115), Expect = 1e-05
Identities = 37/118 (31%), Positives = 46/118 (38%), Gaps = 27/118 (22%)
Query: 22 PAPADLLGGSPHARSSVAHRGSHLP-PAHPRSMGMASLLDGG-SGGGDYHHHHRAPEHSL 79
PA + G+ A + GS +P P HP LL+G +GGG YHH
Sbjct: 576 PADSVAAAGAGAAAAGSGPAGSRVPAPHHPH------LLEGRKAGGGSYHH--------- 620
Query: 80 AGPLHPTMTMACETPPGMSMPTTYTTLTPLQPLPPISTVSDKFPHHHHHHHHHHHPHH 137
+ A G + L P S + PHHHHH HHHHH HH
Sbjct: 621 --------SSAFRPVGGKDDAESLAKLHGASAGAPHS--AQTHPHHHHHPHHHHHHHH 668
Score = 30.4 bits (67), Expect = 3.6
Identities = 27/117 (23%), Positives = 34/117 (29%), Gaps = 8/117 (6%)
Query: 17 SHEPVPAPADLLGGSPHARSSVAHRGSHLPPAHPRSMGMASLLDGGSGGGDY-------- 68
S P P LL G S H + P + L G S G +
Sbjct: 597 SRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTHPHH 656
Query: 69 HHHHRAPEHSLAGPLHPTMTMACETPPGMSMPTTYTTLTPLQPLPPISTVSDKFPHH 125
HHH H P P+ + P + P P PP + PHH
Sbjct: 657 HHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQHPHH 713
>gi|239751555 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 48.9 bits (115), Expect = 1e-05
Identities = 37/118 (31%), Positives = 46/118 (38%), Gaps = 27/118 (22%)
Query: 22 PAPADLLGGSPHARSSVAHRGSHLP-PAHPRSMGMASLLDGG-SGGGDYHHHHRAPEHSL 79
PA + G+ A + GS +P P HP LL+G +GGG YHH
Sbjct: 576 PADSVAAAGAGAAAAGSGPAGSRVPAPHHPH------LLEGRKAGGGSYHH--------- 620
Query: 80 AGPLHPTMTMACETPPGMSMPTTYTTLTPLQPLPPISTVSDKFPHHHHHHHHHHHPHH 137
+ A G + L P S + PHHHHH HHHHH HH
Sbjct: 621 --------SSAFRPVGGKDDAESLAKLHGASAGAPHS--AQTHPHHHHHPHHHHHHHH 668
Score = 30.4 bits (67), Expect = 3.6
Identities = 27/117 (23%), Positives = 34/117 (29%), Gaps = 8/117 (6%)
Query: 17 SHEPVPAPADLLGGSPHARSSVAHRGSHLPPAHPRSMGMASLLDGGSGGGDY-------- 68
S P P LL G S H + P + L G S G +
Sbjct: 597 SRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTHPHH 656
Query: 69 HHHHRAPEHSLAGPLHPTMTMACETPPGMSMPTTYTTLTPLQPLPPISTVSDKFPHH 125
HHH H P P+ + P + P P PP + PHH
Sbjct: 657 HHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQHPHH 713
>gi|239746067 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
Length = 1252
Score = 48.9 bits (115), Expect = 1e-05
Identities = 37/118 (31%), Positives = 46/118 (38%), Gaps = 27/118 (22%)
Query: 22 PAPADLLGGSPHARSSVAHRGSHLP-PAHPRSMGMASLLDGG-SGGGDYHHHHRAPEHSL 79
PA + G+ A + GS +P P HP LL+G +GGG YHH
Sbjct: 576 PADSVAAAGAGAAAAGSGPAGSRVPAPHHPH------LLEGRKAGGGSYHH--------- 620
Query: 80 AGPLHPTMTMACETPPGMSMPTTYTTLTPLQPLPPISTVSDKFPHHHHHHHHHHHPHH 137
+ A G + L P S + PHHHHH HHHHH HH
Sbjct: 621 --------SSAFRPVGGKDDAESLAKLHGASAGAPHS--AQTHPHHHHHPHHHHHHHH 668
Score = 30.4 bits (67), Expect = 3.6
Identities = 27/117 (23%), Positives = 34/117 (29%), Gaps = 8/117 (6%)
Query: 17 SHEPVPAPADLLGGSPHARSSVAHRGSHLPPAHPRSMGMASLLDGGSGGGDY-------- 68
S P P LL G S H + P + L G S G +
Sbjct: 597 SRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTHPHH 656
Query: 69 HHHHRAPEHSLAGPLHPTMTMACETPPGMSMPTTYTTLTPLQPLPPISTVSDKFPHH 125
HHH H P P+ + P + P P PP + PHH
Sbjct: 657 HHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQHPHH 713
>gi|18765752 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1A isoform 2 [Homo sapiens]
Length = 754
Score = 48.1 bits (113), Expect = 2e-05
Identities = 47/164 (28%), Positives = 61/164 (37%), Gaps = 31/164 (18%)
Query: 52 SMGMASLLDGGSGGGDYHHHHRAPEHSLAGPLHPTMTMACETPP--------------GM 97
S G + + G D H HR HS M CET G
Sbjct: 506 SGGSSGTSNSGRARSDPTHQHR---HSGGHFTAAVQAMDCETHSPQVRQQFPAPLGWSGT 562
Query: 98 SMPTTYTTLT-PLQPLP-PISTVSDKFPHHH------HHHHHHHHPHHHQRLAGNVSGSF 149
PT T T P+Q ++ + HHH HHHHHHHH HH Q+ GN +
Sbjct: 563 EAPTQVTVETHPVQETTFHVAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQALGNRT--- 619
Query: 150 TLMRDERGLASMNNLYTPYHKDVAGMGQSLSPLSSSGLGSIHNS 193
R + N+ T +V S++ LSSS S +S
Sbjct: 620 ---RPRVYNSPTNSSSTQDSMEVGHSHHSMTSLSSSTTSSSTSS 660
>gi|18765758 dual-specificity tyrosine-(Y)-phosphorylation regulated
kinase 1A isoform 1 [Homo sapiens]
Length = 763
Score = 48.1 bits (113), Expect = 2e-05
Identities = 47/164 (28%), Positives = 61/164 (37%), Gaps = 31/164 (18%)
Query: 52 SMGMASLLDGGSGGGDYHHHHRAPEHSLAGPLHPTMTMACETPP--------------GM 97
S G + + G D H HR HS M CET G
Sbjct: 515 SGGSSGTSNSGRARSDPTHQHR---HSGGHFTAAVQAMDCETHSPQVRQQFPAPLGWSGT 571
Query: 98 SMPTTYTTLT-PLQPLP-PISTVSDKFPHHH------HHHHHHHHPHHHQRLAGNVSGSF 149
PT T T P+Q ++ + HHH HHHHHHHH HH Q+ GN +
Sbjct: 572 EAPTQVTVETHPVQETTFHVAPQQNALHHHHGNSSHHHHHHHHHHHHHGQQALGNRT--- 628
Query: 150 TLMRDERGLASMNNLYTPYHKDVAGMGQSLSPLSSSGLGSIHNS 193
R + N+ T +V S++ LSSS S +S
Sbjct: 629 ---RPRVYNSPTNSSSTQDSMEVGHSHHSMTSLSSSTTSSSTSS 669
>gi|7710129 LIM domain only 6 [Homo sapiens]
Length = 615
Score = 48.1 bits (113), Expect = 2e-05
Identities = 44/148 (29%), Positives = 56/148 (37%), Gaps = 30/148 (20%)
Query: 15 GVSHEPVPA-----PADLLGGSPHARSSVAHRGSHLPPAHPRSMGMASLLDGGSGGGDYH 69
G S E PA P+ L G+PH S +P P S G +L S G
Sbjct: 411 GTSTELAPATGPEEPSRFLRGAPHRHSMPELGLRSVPEPPPESPGQPNLRPDDSAFG--- 467
Query: 70 HHHRAPEHSLAGPL----HPTMTMACETPPGMSMPTTYTTLTPLQPLPPISTVSDKFPHH 125
P S PL P T++ PP +P P + HH
Sbjct: 468 -RQSTPRVSFRDPLVSEGGPRRTLSA--PPAQRR----------RPRSPPPRAPSRRRHH 514
Query: 126 HHHHHHHHHPH-----HHQRLAGNVSGS 148
HH+HHHHH+ H H+Q AG+ S S
Sbjct: 515 HHNHHHHHNRHPSRRRHYQCDAGSGSDS 542
>gi|114326455 chromodomain helicase DNA binding protein 8 [Homo
sapiens]
Length = 2302
Score = 47.8 bits (112), Expect = 2e-05
Identities = 40/141 (28%), Positives = 55/141 (39%), Gaps = 15/141 (10%)
Query: 12 ELHGVSHEPVPAPADLLGGSPHARSSVAHRGSHLPPA-----------HPRSMGMASLLD 60
EL+ + EPV G H +V +R P A P M +L+
Sbjct: 2096 ELNCLGMEPVQTANSRNGKKGHHTETVFNRVLPGPIAPESSKKRARRMRPDLSKMMALMQ 2155
Query: 61 GGSGGGDYHHHHRAPEHSLAGPLHPTMTMACETPPGMSMPTTYTTLTPLQPLPPISTVSD 120
GGS G H +HS +G L ++ + S+P + P + + S
Sbjct: 2156 GGSTGS--LSLHNTFQHSSSG-LQSVSSLGHSSATSASLPFMPFVMGGAPSSPHVDS-ST 2211
Query: 121 KFPHHHHHHHHHHHPHHHQRL 141
HHHHH H HHH HHH L
Sbjct: 2212 MLHHHHHHPHPHHHHHHHPGL 2232
>gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]
Length = 1488
Score = 47.8 bits (112), Expect = 2e-05
Identities = 45/164 (27%), Positives = 53/164 (32%), Gaps = 24/164 (14%)
Query: 108 PLQPLPPISTVSDKFPHHHHHHHHHHHPHHHQRLAGNVSGSFTLMRDERGLASMNNLYTP 167
P P S S HHHHHHHHH H H G ++ D G + + L+
Sbjct: 1221 PPPPTGQASASSSSASSTHHHHHHHHHGHSH--------GGLGVLPD--GQSKLQALHAQ 1270
Query: 168 YHKDVAGMGQSLSPLSSSGLGSIHNSQQGLPHYAHPGAAMPTDKMLTPNGFEAHHPAMLG 227
Y G G + P S+ Q P G+ P P G H A
Sbjct: 1271 Y---CQGPGPAPPPYLPPQQPSLPPPPQQPPPLPQLGSIPPPPASAPPVGPHRHFHAHGP 1327
Query: 228 RHGEQHLTPTSAGMVPINGLPPHHPHAHLNAQGHGQLLGTAREP 271
G QH T G P G A GH Q R P
Sbjct: 1328 VPGPQHYTLGRPGRAPRRG-----------AGGHPQFAPHGRHP 1360
Score = 42.4 bits (98), Expect = 0.001
Identities = 70/304 (23%), Positives = 94/304 (30%), Gaps = 51/304 (16%)
Query: 17 SHEPVPAPADLLGGSPHARSSVAHRGSHLPPAHPRSMGMASLLDGGSGGGDYHHHHRAPE 76
S PV + LG S +G P P AS S +HHHH
Sbjct: 1194 SQRPVSNSSSFLGS---LFGSKRGKGPFQMPPPPTGQASASSSSASSTHHHHHHHHHGHS 1250
Query: 77 HSLAG-------PLHPTMTMACETP---PGMSMPTTYTTLTP----------LQPLPPIS 116
H G L C+ P P +P +L P L +PP
Sbjct: 1251 HGGLGVLPDGQSKLQALHAQYCQGPGPAPPPYLPPQQPSLPPPPQQPPPLPQLGSIPPPP 1310
Query: 117 TVSDKFPHHHHHHHHHHHPHHHQRLAGNVSGSFTLMRDERGLASMNNLYTPYHKDVAGMG 176
+ H H H H P G R R A + + P+ +
Sbjct: 1311 ASAPPVGPHRHFHAHGPVPGPQHYTLGRPG------RAPRRGAGGHPQFAPHGRHPLHQP 1364
Query: 177 QSLSPLSSSGLGSIHNSQQGLPHYA---HP-------GAAMPTDKMLTPNGFEAHHP--- 223
S PL S +QG H+ HP A P + + HHP
Sbjct: 1365 TSPLPLYSPAPQHPPAHKQGPKHFIFSHHPQMMPAAGAAGGPGSRPPGGSYSHPHHPQSP 1424
Query: 224 ----AMLGRHGEQHLTPTSAGMVPINGLPPHHPHAHLNAQGHGQLLGTAREP--NPSVTG 277
+ + H P + P + LPP PH L+A G GTA P NP
Sbjct: 1425 LSPHSPIPPHPSYPPLPPPSPHTPHSPLPPTSPHGPLHASGPP---GTANPPSANPKAKP 1481
Query: 278 AQVS 281
+++S
Sbjct: 1482 SRIS 1485
>gi|14916427 naked cuticle homolog 2 [Homo sapiens]
Length = 451
Score = 47.4 bits (111), Expect = 3e-05
Identities = 30/97 (30%), Positives = 33/97 (34%), Gaps = 18/97 (18%)
Query: 42 GSHLPPAHPRSMGMASLLDGGSGGGDYHHHHRAPEHSLAGPLHPTMTMACETPPGMSMPT 101
G HLP P G G G H +AP A H + TP G
Sbjct: 369 GHHLPQPPPPPYGHKRYRQKGREG---HSPLKAPHAQPATVEHEVVRDLPPTPAGEGYAV 425
Query: 102 TYTTLTPLQPLPPISTVSDKFPHHHHHHHHHHHPHHH 138
V + HHHHH HHHHH HHH
Sbjct: 426 P---------------VIQRHEHHHHHEHHHHHHHHH 447
>gi|27894361 nuclear receptor subfamily 4, group A, member 3 isoform
b [Homo sapiens]
Length = 637
Score = 47.0 bits (110), Expect = 4e-05
Identities = 14/17 (82%), Positives = 16/17 (94%)
Query: 124 HHHHHHHHHHHPHHHQR 140
+HHHHHHHHHH HHHQ+
Sbjct: 105 YHHHHHHHHHHHHHHQQ 121
Score = 46.2 bits (108), Expect = 6e-05
Identities = 15/28 (53%), Positives = 18/28 (64%)
Query: 113 PPISTVSDKFPHHHHHHHHHHHPHHHQR 140
P I + P +HHHHHHHHH HHH +
Sbjct: 93 PLIKVEEGRAPSYHHHHHHHHHHHHHHQ 120
Score = 46.2 bits (108), Expect = 6e-05
Identities = 14/17 (82%), Positives = 15/17 (88%)
Query: 124 HHHHHHHHHHHPHHHQR 140
HHHHHHHHHHH HH Q+
Sbjct: 106 HHHHHHHHHHHHHHQQQ 122
Score = 43.5 bits (101), Expect = 4e-04
Identities = 13/17 (76%), Positives = 14/17 (82%)
Query: 124 HHHHHHHHHHHPHHHQR 140
HHHHHHHHHHH HQ+
Sbjct: 109 HHHHHHHHHHHQQQHQQ 125
Score = 43.1 bits (100), Expect = 5e-04
Identities = 13/18 (72%), Positives = 14/18 (77%)
Query: 122 FPHHHHHHHHHHHPHHHQ 139
+ HHHHHHHHHHH H Q
Sbjct: 105 YHHHHHHHHHHHHHHQQQ 122
>gi|27894359 nuclear receptor subfamily 4, group A, member 3 isoform
c [Homo sapiens]
Length = 443
Score = 47.0 bits (110), Expect = 4e-05
Identities = 14/17 (82%), Positives = 16/17 (94%)
Query: 124 HHHHHHHHHHHPHHHQR 140
+HHHHHHHHHH HHHQ+
Sbjct: 94 YHHHHHHHHHHHHHHQQ 110
Score = 46.2 bits (108), Expect = 6e-05
Identities = 15/28 (53%), Positives = 18/28 (64%)
Query: 113 PPISTVSDKFPHHHHHHHHHHHPHHHQR 140
P I + P +HHHHHHHHH HHH +
Sbjct: 82 PLIKVEEGRAPSYHHHHHHHHHHHHHHQ 109
Score = 46.2 bits (108), Expect = 6e-05
Identities = 14/17 (82%), Positives = 15/17 (88%)
Query: 124 HHHHHHHHHHHPHHHQR 140
HHHHHHHHHHH HH Q+
Sbjct: 95 HHHHHHHHHHHHHHQQQ 111
Score = 43.5 bits (101), Expect = 4e-04
Identities = 13/17 (76%), Positives = 14/17 (82%)
Query: 124 HHHHHHHHHHHPHHHQR 140
HHHHHHHHHHH HQ+
Sbjct: 98 HHHHHHHHHHHQQQHQQ 114
Score = 43.1 bits (100), Expect = 5e-04
Identities = 13/18 (72%), Positives = 14/18 (77%)
Query: 122 FPHHHHHHHHHHHPHHHQ 139
+ HHHHHHHHHHH H Q
Sbjct: 94 YHHHHHHHHHHHHHHQQQ 111
>gi|27894357 nuclear receptor subfamily 4, group A, member 3 isoform
a [Homo sapiens]
Length = 626
Score = 47.0 bits (110), Expect = 4e-05
Identities = 14/17 (82%), Positives = 16/17 (94%)
Query: 124 HHHHHHHHHHHPHHHQR 140
+HHHHHHHHHH HHHQ+
Sbjct: 94 YHHHHHHHHHHHHHHQQ 110
Score = 46.2 bits (108), Expect = 6e-05
Identities = 15/28 (53%), Positives = 18/28 (64%)
Query: 113 PPISTVSDKFPHHHHHHHHHHHPHHHQR 140
P I + P +HHHHHHHHH HHH +
Sbjct: 82 PLIKVEEGRAPSYHHHHHHHHHHHHHHQ 109
Score = 46.2 bits (108), Expect = 6e-05
Identities = 14/17 (82%), Positives = 15/17 (88%)
Query: 124 HHHHHHHHHHHPHHHQR 140
HHHHHHHHHHH HH Q+
Sbjct: 95 HHHHHHHHHHHHHHQQQ 111
Score = 43.5 bits (101), Expect = 4e-04
Identities = 13/17 (76%), Positives = 14/17 (82%)
Query: 124 HHHHHHHHHHHPHHHQR 140
HHHHHHHHHHH HQ+
Sbjct: 98 HHHHHHHHHHHQQQHQQ 114
Score = 43.1 bits (100), Expect = 5e-04
Identities = 13/18 (72%), Positives = 14/18 (77%)
Query: 122 FPHHHHHHHHHHHPHHHQ 139
+ HHHHHHHHHHH H Q
Sbjct: 94 YHHHHHHHHHHHHHHQQQ 111
>gi|27894355 nuclear receptor subfamily 4, group A, member 3 isoform
a [Homo sapiens]
Length = 626
Score = 47.0 bits (110), Expect = 4e-05
Identities = 14/17 (82%), Positives = 16/17 (94%)
Query: 124 HHHHHHHHHHHPHHHQR 140
+HHHHHHHHHH HHHQ+
Sbjct: 94 YHHHHHHHHHHHHHHQQ 110
Score = 46.2 bits (108), Expect = 6e-05
Identities = 15/28 (53%), Positives = 18/28 (64%)
Query: 113 PPISTVSDKFPHHHHHHHHHHHPHHHQR 140
P I + P +HHHHHHHHH HHH +
Sbjct: 82 PLIKVEEGRAPSYHHHHHHHHHHHHHHQ 109
Score = 46.2 bits (108), Expect = 6e-05
Identities = 14/17 (82%), Positives = 15/17 (88%)
Query: 124 HHHHHHHHHHHPHHHQR 140
HHHHHHHHHHH HH Q+
Sbjct: 95 HHHHHHHHHHHHHHQQQ 111
Score = 43.5 bits (101), Expect = 4e-04
Identities = 13/17 (76%), Positives = 14/17 (82%)
Query: 124 HHHHHHHHHHHPHHHQR 140
HHHHHHHHHHH HQ+
Sbjct: 98 HHHHHHHHHHHQQQHQQ 114
Score = 43.1 bits (100), Expect = 5e-04
Identities = 13/18 (72%), Positives = 14/18 (77%)
Query: 122 FPHHHHHHHHHHHPHHHQ 139
+ HHHHHHHHHHH H Q
Sbjct: 94 YHHHHHHHHHHHHHHQQQ 111
>gi|4505965 POU class 4 homeobox 3 [Homo sapiens]
Length = 338
Score = 46.6 bits (109), Expect = 5e-05
Identities = 77/330 (23%), Positives = 130/330 (39%), Gaps = 71/330 (21%)
Query: 140 RLAGNVSGSF--TLMRDERGLASMNNLYT----PYHKDVAGMGQSLSPLSSSGLGSIHNS 193
+L GN+ GSF +L+ LA+++ + P+ D S P +S+
Sbjct: 40 QLQGNIFGSFDESLLARAEALAAVDIVSHGKNHPFKPDATYHTMSSVPCTSTS------- 92
Query: 194 QQGLPHYAHPGAAMPTDKMLTPNGFEAHHPAMLGRHGE--QHLTPTSAGMVPINGLPPH- 250
+HP A LT + HH G G+ +H++PT + V G P H
Sbjct: 93 --STVPISHPAA-------LTSH---PHHAVHQGLEGDLLEHISPTLS--VSGLGAPEHS 138
Query: 251 ------HPHAHLNAQGH-GQLLGTARE----PNPSVTGAQVSNGSNSGQMEEINTKEVAQ 299
HPH HL A GH Q +G + P+ ++ S+ ++E + +
Sbjct: 139 VMPAQIHPH-HLGAMGHLHQAMGMSHPHTVAPHSAMPACLSDVESDPRELEAFAERFKQR 197
Query: 300 RITTELKRYSIPQAI----------FAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRR 349
RI + + + A+ +Q +CR + L + LK +
Sbjct: 198 RIKLGVTQADVGAALANLKIPGVGSLSQSTICRFES----LTLSHNNMIALKPVLQA--- 250
Query: 350 MWKWLQEPEFQRMSALRLAACKRKEQEHGKDRGNTPKKPRLVFTDVQRRTLHAIFKENKR 409
WL+E E AA + K + G+ K+ R ++R+L A F R
Sbjct: 251 ---WLEEAE---------AAYREKNSKPELFNGSERKRKRTSIAAPEKRSLEAYFAIQPR 298
Query: 410 PSKELQITISQQLGLELSTVSNFFMNARRR 439
PS E I+++L L+ + V +F N R++
Sbjct: 299 PSSEKIAAIAEKLDLKKNVVRVWFCNQRQK 328
>gi|122937233 discs, large (Drosophila) homolog-associated protein 3
[Homo sapiens]
Length = 979
Score = 46.2 bits (108), Expect = 6e-05
Identities = 19/35 (54%), Positives = 21/35 (60%), Gaps = 4/35 (11%)
Query: 123 PHHHHHHHHHHHPHHHQRLAGNVSGSFTLMRDERG 157
PH HHHHHHHH HHHQ G S S +D +G
Sbjct: 219 PHTSHHHHHHHHHHHHQSRHGKRSKS----KDRKG 249
>gi|55770830 chromobox homolog 4 [Homo sapiens]
Length = 560
Score = 45.8 bits (107), Expect = 8e-05
Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 4/72 (5%)
Query: 75 PEHSLAGPLHPTMTMACETPPGMSMPTTYTTLTPLQPLPPISTVSDKFPHHHHHHHHHHH 134
P+ + + L PT E P ++ P + P S PH H HHHHHHH
Sbjct: 340 PQDAGSRKLSPTKEAFGEQPLQLTTKPDLLAWDPARNTHPPS----HHPHPHPHHHHHHH 395
Query: 135 PHHHQRLAGNVS 146
HHH + N+S
Sbjct: 396 HHHHHAVGLNLS 407
>gi|4507973 zinc finger protein of the cerebellum 3 [Homo sapiens]
Length = 467
Score = 45.8 bits (107), Expect = 8e-05
Identities = 39/133 (29%), Positives = 47/133 (35%), Gaps = 24/133 (18%)
Query: 27 LLGGSPH-----ARSSVAHRGSHLPPAHPRSMGMASLLDGGSGGGDYHHHHRAPEHSLAG 81
LL G P S A R +P P MG+ GD H A + A
Sbjct: 4 LLDGGPQFPGLGVGSFGAPRHHEMPNREPAGMGLNPF-------GDSTHAAAAAAAAAAF 56
Query: 82 PLHPTMTMACETPPGMSMPTTYTTLTPLQPLPPISTVSDKFPHHHHHHHHHHHPHHHQRL 141
L P A + G S T P S ++ HHHHHHHHHHH
Sbjct: 57 KLSPAA--AHDLSSGQSSAFT----------PQGSGYANALGHHHHHHHHHHHTSQVPSY 104
Query: 142 AGNVSGSFTLMRD 154
G S +F R+
Sbjct: 105 GGAASAAFNSTRE 117
>gi|4505007 LIM homeobox transcription factor 1, beta [Homo sapiens]
Length = 372
Score = 45.1 bits (105), Expect = 1e-04
Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 8/91 (8%)
Query: 376 EHGKDRGNTPKKPRLVFTDVQRRTLHAIFKENKRPSKELQITISQQLGLELSTVSNFFMN 435
+ GKD PK+PR + T QRR A F+ + +P ++++ T++ + GL + V +F N
Sbjct: 188 DDGKDP-RRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQN 246
Query: 436 AR-------RRSLDKWQDEGSSNSGNSSSSS 459
R RR + + + S G SS
Sbjct: 247 QRAKMKKLARRHQQQQEQQNSQRLGQEVLSS 277
>gi|196114999 special AT-rich sequence binding protein 1 [Homo
sapiens]
Length = 763
Score = 45.1 bits (105), Expect = 1e-04
Identities = 31/88 (35%), Positives = 47/88 (53%), Gaps = 6/88 (6%)
Query: 280 VSNGSNSGQMEEINTK-----EVAQRITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNP 334
VS N ++++T E+ Q + ELKR I QA+FA+ R+QG LS++LR
Sbjct: 353 VSRSMNKPLEQQVSTNTEVSSEIYQWVRDELKRAGISQAVFARVAFNRTQGLLSEILRKE 412
Query: 335 K-PWSKLKSGRETFRRMWKWLQEPEFQR 361
+ P + +S R M +LQ PE +R
Sbjct: 413 EDPKTASQSLLVNLRAMQNFLQLPEAER 440
Score = 40.4 bits (93), Expect = 0.003
Identities = 32/108 (29%), Positives = 49/108 (45%), Gaps = 7/108 (6%)
Query: 257 NAQGHGQLLGTAREPNPSVTGAQVS---NGSNSGQMEEINTKEVAQRITTELKRYSIPQA 313
+A G L+ T P V A ++ NG IN + I E+KR + QA
Sbjct: 456 SAMGPAPLISTPPSRPPQVKTATIATERNGKPENNTMNINAS-IYDEIQQEMKRAKVSQA 514
Query: 314 IFAQRVLCRSQGTLSDLLR---NPKPWSKLKSGRETFRRMWKWLQEPE 358
+FA+ +SQG L +LLR +P P ++ + R + L +PE
Sbjct: 515 LFAKVAATKSQGWLCELLRWKEDPSPENRTLWENLSMIRRFLSLPQPE 562
>gi|4506791 special AT-rich sequence binding protein 1 [Homo
sapiens]
Length = 763
Score = 45.1 bits (105), Expect = 1e-04
Identities = 31/88 (35%), Positives = 47/88 (53%), Gaps = 6/88 (6%)
Query: 280 VSNGSNSGQMEEINTK-----EVAQRITTELKRYSIPQAIFAQRVLCRSQGTLSDLLRNP 334
VS N ++++T E+ Q + ELKR I QA+FA+ R+QG LS++LR
Sbjct: 353 VSRSMNKPLEQQVSTNTEVSSEIYQWVRDELKRAGISQAVFARVAFNRTQGLLSEILRKE 412
Query: 335 K-PWSKLKSGRETFRRMWKWLQEPEFQR 361
+ P + +S R M +LQ PE +R
Sbjct: 413 EDPKTASQSLLVNLRAMQNFLQLPEAER 440
Score = 40.4 bits (93), Expect = 0.003
Identities = 32/108 (29%), Positives = 49/108 (45%), Gaps = 7/108 (6%)
Query: 257 NAQGHGQLLGTAREPNPSVTGAQVS---NGSNSGQMEEINTKEVAQRITTELKRYSIPQA 313
+A G L+ T P V A ++ NG IN + I E+KR + QA
Sbjct: 456 SAMGPAPLISTPPSRPPQVKTATIATERNGKPENNTMNINAS-IYDEIQQEMKRAKVSQA 514
Query: 314 IFAQRVLCRSQGTLSDLLR---NPKPWSKLKSGRETFRRMWKWLQEPE 358
+FA+ +SQG L +LLR +P P ++ + R + L +PE
Sbjct: 515 LFAKVAATKSQGWLCELLRWKEDPSPENRTLWENLSMIRRFLSLPQPE 562
>gi|33859670 leucine-rich repeats and calponin homology (CH) domain
containing 1 [Homo sapiens]
Length = 728
Score = 45.1 bits (105), Expect = 1e-04
Identities = 16/28 (57%), Positives = 18/28 (64%)
Query: 110 QPLPPISTVSDKFPHHHHHHHHHHHPHH 137
QP P +V+ P HH HHHHHHH HH
Sbjct: 9 QPFVPALSVATLHPLHHPHHHHHHHQHH 36
Score = 36.2 bits (82), Expect = 0.065
Identities = 15/39 (38%), Positives = 19/39 (48%)
Query: 110 QPLPPISTVSDKFPHHHHHHHHHHHPHHHQRLAGNVSGS 148
+P P + +S H HH HHHHH H H G G+
Sbjct: 7 EPQPFVPALSVATLHPLHHPHHHHHHHQHHGGTGAPGGA 45
Score = 35.8 bits (81), Expect = 0.085
Identities = 14/36 (38%), Positives = 18/36 (50%)
Query: 99 MPTTYTTLTPLQPLPPISTVSDKFPHHHHHHHHHHH 134
M T + P P ++T+ HHHHHHH HH
Sbjct: 1 MATPGSEPQPFVPALSVATLHPLHHPHHHHHHHQHH 36
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.129 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,965,402
Number of Sequences: 37866
Number of extensions: 1107557
Number of successful extensions: 8808
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 216
Number of HSP's successfully gapped in prelim test: 112
Number of HSP's that attempted gapping in prelim test: 5535
Number of HSP's gapped (non-prelim): 1607
length of query: 465
length of database: 18,247,518
effective HSP length: 106
effective length of query: 359
effective length of database: 14,233,722
effective search space: 5109906198
effective search space used: 5109906198
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.