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Search of human proteins with 239757130
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
(855 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 1731 0.0
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 1625 0.0
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 1037 0.0
gi|163965366 nascent polypeptide-associated complex alpha subuni... 211 2e-54
gi|116284392 mucin 2 precursor [Homo sapiens] 165 2e-40
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 153 6e-37
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 152 2e-36
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 152 2e-36
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 152 2e-36
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 152 2e-36
gi|47132519 Ras association and pleckstrin homology domains 1 is... 150 4e-36
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 146 9e-35
gi|112421108 capicua homolog [Homo sapiens] 144 3e-34
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 141 2e-33
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 140 5e-33
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 140 5e-33
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 138 2e-32
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 138 2e-32
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 138 2e-32
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 138 2e-32
gi|110832843 TBP-associated factor 4 [Homo sapiens] 137 4e-32
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi... 133 6e-31
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 131 3e-30
gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapi... 130 5e-30
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 130 7e-30
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 128 2e-29
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 128 2e-29
gi|160707881 formin 2 [Homo sapiens] 126 7e-29
gi|150170670 piccolo isoform 2 [Homo sapiens] 124 3e-28
gi|150378539 piccolo isoform 1 [Homo sapiens] 124 3e-28
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 1731 bits (4482), Expect = 0.0
Identities = 855/855 (100%), Positives = 855/855 (100%)
Query: 1 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60
MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE
Sbjct: 1 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60
Query: 61 RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA 120
RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA
Sbjct: 61 RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA 120
Query: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 180
SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS
Sbjct: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 180
Query: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240
RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR
Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240
Query: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300
SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS
Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300
Query: 301 SSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPAT 360
SSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPAT
Sbjct: 301 SSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPAT 360
Query: 361 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL 420
PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL
Sbjct: 361 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL 420
Query: 421 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 480
ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ
Sbjct: 421 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 480
Query: 481 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG 540
VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG
Sbjct: 481 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG 540
Query: 541 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 600
QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG
Sbjct: 541 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 600
Query: 601 PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPD 660
PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPD
Sbjct: 601 PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPD 660
Query: 661 AELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG 720
AELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG
Sbjct: 661 AELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG 720
Query: 721 ALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAE 780
ALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAE
Sbjct: 721 ALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAE 780
Query: 781 GAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSPLDESRASITSVTSFSPDDVA 840
GAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSPLDESRASITSVTSFSPDDVA
Sbjct: 781 GAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSPLDESRASITSVTSFSPDDVA 840
Query: 841 SPQGDWTVVEVETFH 855
SPQGDWTVVEVETFH
Sbjct: 841 SPQGDWTVVEVETFH 855
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 1625 bits (4207), Expect = 0.0
Identities = 813/855 (95%), Positives = 814/855 (95%), Gaps = 39/855 (4%)
Query: 1 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60
MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE
Sbjct: 1 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60
Query: 61 RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA 120
RAGGIGGATIPESAPRAGPTR+ SRPPASGRGERAPPAKNTSPGPVSSPGRA
Sbjct: 61 RAGGIGGATIPESAPRAGPTRT---------SRPPASGRGERAPPAKNTSPGPVSSPGRA 111
Query: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 180
SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS
Sbjct: 112 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 171
Query: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240
RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR
Sbjct: 172 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 231
Query: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300
SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS
Sbjct: 232 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 291
Query: 301 SSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPAT 360
SSPLAT P P APPSPSAPPSLQTLPSPPAT
Sbjct: 292 SSPLAT------------------------------PSPSAPPSPSAPPSLQTLPSPPAT 321
Query: 361 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL 420
PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL
Sbjct: 322 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL 381
Query: 421 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 480
ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ
Sbjct: 382 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 441
Query: 481 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG 540
VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG
Sbjct: 442 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG 501
Query: 541 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 600
QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG
Sbjct: 502 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 561
Query: 601 PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPD 660
PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPD
Sbjct: 562 PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPD 621
Query: 661 AELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG 720
AELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG
Sbjct: 622 AELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG 681
Query: 721 ALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAE 780
ALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAE
Sbjct: 682 ALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAE 741
Query: 781 GAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSPLDESRASITSVTSFSPDDVA 840
GAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSPLDESRASITSVTSFSPDDVA
Sbjct: 742 GAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSPLDESRASITSVTSFSPDDVA 801
Query: 841 SPQGDWTVVEVETFH 855
SPQGDWTVVEVETFH
Sbjct: 802 SPQGDWTVVEVETFH 816
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 1037 bits (2682), Expect = 0.0
Identities = 607/990 (61%), Positives = 644/990 (65%), Gaps = 155/990 (15%)
Query: 11 GAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70
G A P A R P P P +PA R AAG P R
Sbjct: 145 GKATEAPKRSALSAGARRDTSGPTPGTP-SPAMARRSRAAGTEVGLP---RPAPSARPRP 200
Query: 71 PESAPRAGPTRSAGTSSRNP---ASRPPASGRGERAPPAKNTSPG--PVSSPGR----AS 121
P PR + ++ S+ P A R P++G G + P +++ S P+SSP R A
Sbjct: 201 PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSAR 260
Query: 122 GTTR----PGPLGQKGLRISAEETVARGKATEAPKRSALSAG--ARRDTSG----PTP-- 169
GT R P KGL+ V + AP LS+ A SG P P
Sbjct: 261 GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPP 320
Query: 170 ---GTPSPAMARRSRAAGTEVGLPRPAPSARPR----------PPTEGPRKSVSSASE-- 214
TP PA S T + L P+PSA P PP++ P + +
Sbjct: 321 DNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAP 380
Query: 215 ------------HSTTEPSPAARRRPSAGGGLQRPASR---SLSSSATPLSSPARSGPSA 259
HS T PS A P A LQ S +L ++ + L+ R ++
Sbjct: 381 PSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQAS 440
Query: 260 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS----------SPLATPSP 309
+P PA P L P P + +PA+ PLSS S LA+ SP
Sbjct: 441 LTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSP 500
Query: 310 SAALQSQ-----------APPTL---PA--------------------------TPHSSS 329
A L S APP+L PA TPH +
Sbjct: 501 QAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLET 560
Query: 330 LTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPL 389
C PL APPSP P +T PS ATPP QA +L SP LQ LPSPPLSPL
Sbjct: 561 PPCPAPCPLQ-APPSPLTTPPPET-PSSIATPPPQAPPALASPPLQG----LPSPPLSPL 614
Query: 390 ATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 449
ATPPPQAPP LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ
Sbjct: 615 ATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 674
Query: 450 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 509
APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP
Sbjct: 675 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 734
Query: 510 LQ--------------------------------------------LAKPPPQAPPALAT 525
LQ LAKPPPQAPPALAT
Sbjct: 735 LQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALAT 794
Query: 526 PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 585
PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA
Sbjct: 795 PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 854
Query: 586 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 645
PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY
Sbjct: 855 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 914
Query: 646 DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCT 705
DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCT
Sbjct: 915 DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCT 974
Query: 706 IYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASV 765
IYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASV
Sbjct: 975 IYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASV 1034
Query: 766 VQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSPLDESR 825
VQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSPLDESR
Sbjct: 1035 VQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSPLDESR 1094
Query: 826 ASITSVTSFSPDDVASPQGDWTVVEVETFH 855
ASITSVTSFSPDDVASPQGDWTVVEVETFH
Sbjct: 1095 ASITSVTSFSPDDVASPQGDWTVVEVETFH 1124
Score = 904 bits (2335), Expect = 0.0
Identities = 560/968 (57%), Positives = 589/968 (60%), Gaps = 181/968 (18%)
Query: 1 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60
MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE
Sbjct: 1 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60
Query: 61 RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA 120
RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA
Sbjct: 61 RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA 120
Query: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 180
SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS
Sbjct: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 180
Query: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240
RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR
Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240
Query: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300
SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS
Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300
Query: 301 SSPLATPSPSAA-LQSQAPPTLPATPHSSSL--TCQLATPLPLAPPSPSAPPSLQTLPSP 357
SSPLATPSPS + PP ATP ++L + LATPLPLAPPSPSAPPSLQTLPSP
Sbjct: 301 SSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP 360
Query: 358 PATPPS----------------------------------------------QATTSLGS 371
PATPPS QATTSLGS
Sbjct: 361 PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGS 420
Query: 372 PTLQATHSFL-------------PSPPLS-PLATPPPQAPPAL-ALPPLQAPPSPPASPP 416
PTLQATHSFL PS P S P +PP QAP +L A PPLQ SP SP
Sbjct: 421 PTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPL 480
Query: 417 LSPLATPSPQAPNALAVHLLQAPFS-------------PPPS------------------ 445
SPL QA ++LA H QAP S PPS
Sbjct: 481 SSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPS 540
Query: 446 ---PPVQAPFSP---------------PASPPVSPSATPPSQAPPSLAAPPLQVPP---S 484
PP+Q +P P P SP TPP + P S+A PP Q PP S
Sbjct: 541 LAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALAS 600
Query: 485 PP----ASPPMSPSATPPPQAPPPLAAPPLQ-------------LAKPPPQAPPALATPP 527
PP SPP+SP ATPPPQAPP LA PPLQ LA P PQAP ALA
Sbjct: 601 PPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL 660
Query: 528 LQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR 587
LQA SPP S P QAPFSP AS P+SP ATPP QAPP LAAP LQVPPSPPASP +
Sbjct: 661 LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA 720
Query: 588 RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST--------LSGPDLAGHSSSATSTP 639
PP P + P L + P PP P SPS+T L+ P L S S P
Sbjct: 721 TPPPQAPPPLAAPP---LQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLP 777
Query: 640 EELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRG----APGAPLPWPP-A 694
A PPP A A P + P+PP +F G +P A LP P A
Sbjct: 778 M-----------SPLAKPPPQAPPALATPPLQAL-PSPPASFPGQAPFSPSASLPMSPLA 825
Query: 695 TGPGSADGLCTIYETEGPESATPAPGAL------DPGPSPGTSGGKAAAGAGAG---ASS 745
T P A + + P S +P PGP SG + G S
Sbjct: 826 TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 885
Query: 746 RSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAA 805
RSP G + H S T + E G G GGA AA
Sbjct: 886 RSPSSTLSG--------PDLAGHSSSAT---STPEELRGYDSGPEGGAAASPPPDAELAA 934
Query: 806 LSDAELGR 813
A R
Sbjct: 935 CHPAAWSR 942
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 211 bits (537), Expect = 2e-54
Identities = 219/780 (28%), Positives = 303/780 (38%), Gaps = 104/780 (13%)
Query: 9 KAGAAARTP--AARAPGLLTPRPPGSPRPPP----PVTPAALRVLGAAGAVGRKPLAERA 62
K G A +P A P + P P GSP P TP A G+ PL + A
Sbjct: 997 KGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGA 1056
Query: 63 GGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSS--PGRA 120
AT+P +P+ GP + + P + P S +G A P+ +P P ++ P
Sbjct: 1057 PTTPAATLP--SPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPK 1114
Query: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 180
G P G + + G AT PK + + A + TP P A +
Sbjct: 1115 GGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTT 1174
Query: 181 RAA---GTEVGLPRPAPSARPRPPTEGPRKSVSS-ASEHSTTEPSPAARRRPSAGGGLQR 236
AA + GL P+P P P P A+ P+ A PS GGL
Sbjct: 1175 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT 1234
Query: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV-----TPPRKD 291
P+ + ++PA + PS +G P P P P A PP + TPP K
Sbjct: 1235 PSPKGAP------TTPAATPPSPKGGPATPPPKGAPTP---PAATPPSLKGGLATPPHKG 1285
Query: 292 A---------APALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAP 342
A +P GP +S P P+P AA PP+ +P TP P
Sbjct: 1286 APNPAVVTPPSPKGGPATSPPKGAPTPPAA----TPPSPKGSP---------GTPPPKGA 1332
Query: 343 PSPSA--PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLS-------PLATPP 393
P+P A PPS + P+ PAT PS S G PT ++ P+PP + P TPP
Sbjct: 1333 PTPPAVTPPSPKGTPTLPATTPS----SKGGPTTPSSKEG-PTPPAATPSHKGGPAMTPP 1387
Query: 394 -PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 452
P+ PA+ P + P+ PA PLSP P+ A + +PP PV
Sbjct: 1388 SPKRGPAIPSP--KGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKK 1445
Query: 453 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP--PPQAPPPLAAPPL 510
+P S P ATP S+ P+L A P PPA ++ S++P P P P+ AP L
Sbjct: 1446 APATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTL 1505
Query: 511 QLAKP--PPQAPPALATPPLQALP-SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 567
P P + P ATP + P +P A+ + +P+ P L P P
Sbjct: 1506 PAVIPSSPKEVP---ATPSSRRDPIAPTATLLSKK--TPATLAPKEALIPPAMTVPSPKK 1560
Query: 568 APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLAL------APGP---PPPPSRS 618
P + P PA+P+ + PP P T P L +P P P PP+ +
Sbjct: 1561 TPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVT 1620
Query: 619 PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP- 677
P S GP + TS P P A+ + ++ A P A PA
Sbjct: 1621 PPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVT----CKMGATVPQASKGLPAKK 1676
Query: 678 -PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPE----SATPAPGALDPGPSPGTSG 732
P A + AP P + + T +GP+ SAT P DP G+ G
Sbjct: 1677 GPTALKEVLVAPAP--------ESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKG 1728
Score = 207 bits (528), Expect = 3e-53
Identities = 230/788 (29%), Positives = 303/788 (38%), Gaps = 101/788 (12%)
Query: 26 TPRPPGSPRPPPPV---TPAALRVLGAAGAVGRKPLAERAGGIGGATIPES-----APRA 77
+P SP PP P TP+A+ L G V P + P+ AP+
Sbjct: 849 SPATTHSPTPPSPKGAPTPSAVTPLSPKG-VTLPPKETPTPSVVNLPFPKEGPATPAPKQ 907
Query: 78 GPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSS--PGRASGTTRPGPLGQKGLR 135
P S +SS A PA +G A P+ +P P ++ P G P P
Sbjct: 908 APALSMTSSSPKKARATPAP-KGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPP 966
Query: 136 ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA------GTEVGL 189
+ + G AT +PK + A + P TPSP A A G+
Sbjct: 967 AATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAAT 1026
Query: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249
P P ++ P T K +A+ P+ A PS GG PA+ SL + TP
Sbjct: 1027 PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG---PATPSLKGAPTP- 1082
Query: 250 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP---LSSSPLAT 306
PA + PS +G P P+ PKG A PP TPP A P ++P AT
Sbjct: 1083 --PAATPPSPKGGPATPS------PKG--APMPPAATPPSPKGGLATPPHKGAPTTPAAT 1132
Query: 307 P-SPSAALQSQAPPTLPATPHSSSLTCQ--LATPLP--------LAPPSPS---APPSLQ 352
P SP L + P P TP ++ + + LATP P PPSP A PS +
Sbjct: 1133 PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPK 1192
Query: 353 TLPSPPATPPSQATTSLGSPTLQA---THSFLPSPPLSPLATPPPQAPPALALPPLQAPP 409
P+ PA P L +P+ + T + P P LATP P+ P P PP
Sbjct: 1193 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT---TPAATPP 1249
Query: 410 SP---PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP---S 463
SP PA+PP TP P +L L P P+P V P SP P SP +
Sbjct: 1250 SPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGA 1309
Query: 464 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP-PLAAPPLQLAKPPPQAPPA 522
TPP+ PPS P P +PP + TPP PP P P L P + P
Sbjct: 1310 PTPPAATPPS--------PKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGP- 1360
Query: 523 LATPPLQALPSPPASFP----GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 578
TP + P+PPA+ P G A PS P A P P+ P A + P P
Sbjct: 1361 -TTPSSKEGPTPPAATPSHKGGPAMTPPS---PKRGPAIPSPKGDPTSPAVIPLSPKKAP 1416
Query: 579 ASPTLQAPRRPPTPGPDTSVSGPRLTLALAP------GPPPPPSRSPSSTLSGPDLAGHS 632
A+P + P+ G T + ++L AP G P PS TL P + S
Sbjct: 1417 ATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTL--PAVTPPS 1474
Query: 633 SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRG--APGAPL- 689
P+++ S + A +P L A P++ PA P + R AP A L
Sbjct: 1475 PKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLL 1534
Query: 690 --PWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSR- 746
P P A I S P P +P T K A+ A S
Sbjct: 1535 SKKTPATLAPKEA----LIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTY 1590
Query: 747 ----SPKQ 750
SPK+
Sbjct: 1591 KGAPSPKE 1598
Score = 203 bits (516), Expect = 6e-52
Identities = 222/731 (30%), Positives = 292/731 (39%), Gaps = 173/731 (23%)
Query: 9 KAGAAARTPAARAPGLLTPRPPGSPRPPPP---VTPAALRVLGAAGAVGRKPLAERAGGI 65
+A A + T ++ TP P G P P P TP A
Sbjct: 907 QAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPA---------------------- 944
Query: 66 GGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR 125
AT P +P+ GP + + P + P S +G A P+ +P P ++ T
Sbjct: 945 --ATPP--SPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAA-------TP 993
Query: 126 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT 185
P P G G AT +PK PTP +P + S AA
Sbjct: 994 PSPKG--------------GPATPSPK------------GAPTPPAVTPPSPKGSPAA-- 1025
Query: 186 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 245
P P ++ P T K +A+ P+ A PS GG PA+ SL +
Sbjct: 1026 ---TPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG---PATPSLKGA 1079
Query: 246 ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP---LSSS 302
TP PA + PS +G P+ P PKG A PP TPP A P ++
Sbjct: 1080 PTP---PAATPPSPKG------GPATPSPKG--APMPPAATPPSPKGGLATPPHKGAPTT 1128
Query: 303 PLAT-PSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSP----SAPPSLQTLPSP 357
P AT PSP L + P P TP ++ PPSP + PP +P
Sbjct: 1129 PAATPPSPKGGLATPPPKGAPTTPAAT-------------PPSPKGGLATPPPKGAPTTP 1175
Query: 358 PATPPSQ----ATTS-LGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP 412
ATPPS AT S G+PT T + P P LATP P+ P P PPSP
Sbjct: 1176 AATPPSPKGGLATPSPKGAPT---TPAATPPSPKGGLATPSPKGAPT---TPAATPPSPK 1229
Query: 413 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 472
LATPSP+ AP +P +PP +P PA+PP + TPP+ PP
Sbjct: 1230 GG-----LATPSPKG----------APTTPAATPP--SPKGGPATPPPKGAPTPPAATPP 1272
Query: 473 S----LAAPPLQVPPSP----PASPPMSPSATPPPQAP-PPLAAPPLQLAK---PPPQ-- 518
S LA PP + P+P P SP P+ +PP AP PP A PP PPP+
Sbjct: 1273 SLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGA 1332
Query: 519 -APPALATPPLQALPSPPASFPGQ--APFSPSASL-PMSPLATPPPQAPPVLAAPLLQVP 574
PPA+ P + P+ PA+ P P +PS+ P P ATP + P + P
Sbjct: 1333 PTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAM------TP 1386
Query: 575 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 634
PSP P + +P+ PT S + L+ P P +R ++T S DL +
Sbjct: 1387 PSPKRGPAIPSPKGDPT-------SPAVIPLSPKKAPATPVTREGAATPSKGDL----TP 1435
Query: 635 ATSTPEELR--GYDSGPEGG-AAASPPPDAELAACHPAAWSRGPAPPLAF-----RGAPG 686
TP L+ S P+GG A S D L A P + PAP + AP
Sbjct: 1436 PAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPA 1495
Query: 687 APLPWPPATGP 697
P P T P
Sbjct: 1496 TPAPMGAPTLP 1506
Score = 200 bits (508), Expect = 5e-51
Identities = 200/699 (28%), Positives = 269/699 (38%), Gaps = 76/699 (10%)
Query: 13 AARTPAARAP----GLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRK--PLAERAGGIG 66
A TPAA P GL TP P G+P P P+ L G P A G
Sbjct: 1171 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1230
Query: 67 GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSP-GRASGTTR 125
G P +P+ PT PA+ PP+ G PP K P ++P G
Sbjct: 1231 GLATP--SPKGAPT--------TPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLAT 1280
Query: 126 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT 185
P G + + G AT PK + A + +PGTP P + A T
Sbjct: 1281 PPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPP------KGAPT 1334
Query: 186 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 245
+ P+P P P P + S P+P A GG P S
Sbjct: 1335 PPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPS------ 1388
Query: 246 ATPLSSPARSGPSARGTPRAPAH-PSQPKPKGLQALRPPQVTPPRKDAA-PALGPLSSSP 303
P PA PS +G P +PA P PK + P R+ AA P+ G L+
Sbjct: 1389 --PKRGPAI--PSPKGDPTSPAVIPLSPK-------KAPATPVTREGAATPSKGDLTPPA 1437
Query: 304 LATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPS 363
+ S A + AP PATP SS L P +P P AP + T SP P +
Sbjct: 1438 VTPVSLKKAPATSAPKGGPATP-SSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPAT 1496
Query: 364 QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATP 423
A +G+PTL A +PS P ATP + P L + +P P L P
Sbjct: 1497 PAP--MGAPTLPAV---IPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPP 1551
Query: 424 SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPP 483
+ P+ + P P +P + SPPA V+PS + +P L PP P
Sbjct: 1552 AMTVPSPKKTPAIPTPKEAPATPSSKEASSPPA---VTPSTYKGAPSPKELLIPPAVTSP 1608
Query: 484 SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL---ATPPLQALPSPPASFPG 540
SP + P P+ TPP P P PP P +L T P A+ P
Sbjct: 1609 SPKEA-PTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQ 1667
Query: 541 QAPFSPSASLPMS---PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS 597
+ P+ P + L P P++ P++ AP + P + +S T +P P P
Sbjct: 1668 ASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSAT--SPPICPDPSAKNG 1725
Query: 598 VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAA--- 654
GP T +AP P P + S T G D A HS P E + S P AA
Sbjct: 1726 SKGPLST--VAPAPLLPVQKDSSKTAKGKD-ASHSPKGPLAPPESKA--STPLTAAAFEK 1780
Query: 655 ASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPP 693
P P++ A+ S P+PP++ AP +P+P P
Sbjct: 1781 VLPKPES-------ASVSAAPSPPVSLPLAP-SPVPTLP 1811
Score = 147 bits (370), Expect = 5e-35
Identities = 178/626 (28%), Positives = 239/626 (38%), Gaps = 98/626 (15%)
Query: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVG--RKPLAERAGG 64
K A TP + G T P G+P PP P+ G G P
Sbjct: 1284 KGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSP 1343
Query: 65 IGGATIPESAP-----------RAGPTRSAGTSSR--NPASRPPASGRGERAPPAKN--T 109
G T+P + P + GPT A T S PA PP+ RG P K T
Sbjct: 1344 KGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPT 1403
Query: 110 SPGPVS-SPGRASGT--TRPGPL----GQKGLRISAEETVARGKATEAPKRSALSAGARR 162
SP + SP +A T TR G G ++ + AT APK + ++
Sbjct: 1404 SPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG 1463
Query: 163 DTSGP--TPGTPS--PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 218
D + P TP +P PA + + ++ + PAP P P P SS E T
Sbjct: 1464 DPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIP----SSPKEVPAT 1519
Query: 219 EPSPAARRRPSAGGGLQRPASRSLSSSATP--------LSSPARSGPSARGTPRAPAHPS 270
P++RR P A + +L S TP L PA + PS + TP P
Sbjct: 1520 ---PSSRRDPIA-------PTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKE 1569
Query: 271 QP-KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSS 329
P P +A PP VTP AP+ L P T SPS P P +P
Sbjct: 1570 APATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVT-SPSPKEAPTPPAVTPPSPEKGP 1628
Query: 330 LTCQLATPLPLAPPS--PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFL----PS 383
ATP P P+ P P SL+ P T P+ T +G+ QA+ P+
Sbjct: 1629 -----ATPAPKGTPTSPPVTPSSLKDSP----TSPASVTCKMGATVPQASKGLPAKKGPT 1679
Query: 384 PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 443
L P P++ P + P + P + +S SP P P A N L + +P
Sbjct: 1680 ALKEVLVAPAPESTPIITAPTRKGPQTKKSS-ATSPPICPDPSAKNGSKGPL--STVAPA 1736
Query: 444 PSPPVQ-----------APFSP--PASPPVSPSATPPSQAP-----PSLAAPPLQVPPSP 485
P PVQ A SP P +PP S ++TP + A P + + PSP
Sbjct: 1737 PLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSP 1796
Query: 486 PASPPMSPSATP--PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 543
P S P++PS P PP+ ++P L L P PA L +P P S G P
Sbjct: 1797 PVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPIS--GGVP 1854
Query: 544 FS------PSASLPMSPLATPPPQAP 563
F P+ P+ TP + P
Sbjct: 1855 FQSVLVNMPTPKSAGIPVPTPSAKQP 1880
Score = 143 bits (361), Expect = 6e-34
Identities = 210/781 (26%), Positives = 284/781 (36%), Gaps = 101/781 (12%)
Query: 16 TPAARAPGLLTPRPPGS--------PRPPPPVTPAALRVLGAAGAVG---RKPLAERAGG 64
+PAA + P+ P + P PP P L+ L ++ V +K L
Sbjct: 479 SPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPAS 538
Query: 65 IGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTT 124
+ GA P ++ T+ ++P P + +P ++TS P P T
Sbjct: 539 LEGAPF-------SPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSP-EIPLSPEATL 590
Query: 125 RPGPLGQKGLRISAEETVARGKATEA---PKRSALSAGARRDTSGPTPGTPSPAMARRSR 181
LG E + GK + P SA + S P + P + + S
Sbjct: 591 AKKSLG---------EPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLL-KSSL 640
Query: 182 AAGTEVGLPRPAPSARPRPPT--EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR-PA 238
T P + PT +G ++AS S A + P G L P
Sbjct: 641 ITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPL 700
Query: 239 SRSLSSSATPLSSPARSGPSARGTPRAPAHP-SQPKPKGLQALRPPQVTPPRKDAAP--- 294
+ S + SP + AP P S P P PP TPP
Sbjct: 701 VPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPS-----LPPAGTPPGTKKVDGIS 755
Query: 295 ---ALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLA---PPSPSAP 348
AL P++SSP P+ + + A +LT +P PL P P
Sbjct: 756 HTSALAPVASSPKECPTEDSGASATASS-------KGTLTYLADSPSPLGVSVSPQTKRP 808
Query: 349 PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL-QA 407
P+ + P TP +L SP SFLP LS + A PP +
Sbjct: 809 PTKKGSAGPD-TPIG----NLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKG 863
Query: 408 PPSPPASPPLSP--LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 465
P+P A PLSP + P + P V+L PF P + P +P +P +P+ +
Sbjct: 864 APTPSAVTPLSPKGVTLPPKETPTPSVVNL---PF------PKEGPATP--APKQAPALS 912
Query: 466 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT 525
S +P A P P PASP SP P P P A PP P +P T
Sbjct: 913 MTSSSPKKARATP--APKGIPASP--SPKGAPTP----PAATPPSPKGGPATPSPKWAPT 964
Query: 526 PPLQALPSP---PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 582
PP PSP PA+ + +P A+ P SP P +P P PPSP SP
Sbjct: 965 PPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA 1024
Query: 583 LQA-PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEE 641
P+ TP P + P+ + A P P P+ +P++TL P + S P
Sbjct: 1025 ATPFPKGASTP-PAATPPSPKGSPAATPLPKGAPT-TPAATLPSPKGGPATPSLKGAPTP 1082
Query: 642 LRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSAD 701
P+GG A P A + PAA P LA GAP P AT P
Sbjct: 1083 PAATPPSPKGGPATPSPKGAPMP---PAATPPSPKGGLATPPHKGAPTT-PAATPPSPKG 1138
Query: 702 GLCTIYETEGPESATPAPGALDPGPSPG--TSGGKAAAGAGAGASSRSPKQARLGELPLG 759
GL T P+ A P A P P G T K A A A+ SPK P G
Sbjct: 1139 GLA----TPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPA-ATPPSPKGGLATPSPKG 1193
Query: 760 A 760
A
Sbjct: 1194 A 1194
Score = 114 bits (285), Expect = 4e-25
Identities = 224/902 (24%), Positives = 317/902 (35%), Gaps = 176/902 (19%)
Query: 10 AGAAARTPAARAPGLLTPRPPGSPRPP--------PPVTPAALRVLGAAGAVGRKP---L 58
A + +T + P + P P G+P PP VTP A G A P L
Sbjct: 180 APSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTL 239
Query: 59 AERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPA---------------SGRGERA 103
A + + TI S+ P S + P S P A G
Sbjct: 240 AIASPQVKDTTI--SSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNT 297
Query: 104 PPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV-------ARGKATEAPKRSAL 156
PP S G +P S LGQ G ++ TV + A+ +RS +
Sbjct: 298 PPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVI 357
Query: 157 SAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE---GPRKSVSSAS 213
R+ P P +A + + +PS T P S+ S
Sbjct: 358 PPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKS 417
Query: 214 EHSTTEPSPAARRRPSAGGG-----LQRPASRSLSSS-----ATPLSSPARSGPSARGTP 263
+ T P + P + G + P + + + + AT +S P SGP + P
Sbjct: 418 SPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEP 477
Query: 264 RAPA-------HPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQ 316
+PA P +P + LR P V+PP D L L SS L LQ+
Sbjct: 478 TSPAALVMAPVAPKEPSTQVATTLRIP-VSPPLPDPED-LKNLPSSVLVKFPTQKDLQT- 534
Query: 317 APPTL---PATPHSSSLTCQL-ATPLPLAPPSPSAPPSLQTLPSPPATPPSQATT----S 368
P +L P +P + LT + T LPL +P PS Q+ S P P S T S
Sbjct: 535 VPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKS 594
Query: 369 LGSP-TLQATHSFLPSP----------------------PL--SPLATPPPQAPPALALP 403
LG P + S + SP PL S L TP A P +
Sbjct: 595 LGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESAD 654
Query: 404 PLQAPP---------SPPASP-----------------------PLSPLAT------PSP 425
P P + ASP PL P A+ PSP
Sbjct: 655 PAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSP 714
Query: 426 QAPNALAVHLLQAPFSPP--PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPP 483
Q A L+ AP P PSP + +PP + V + + AP +A+ P + P
Sbjct: 715 QNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAP--VASSPKECPT 772
Query: 484 SPPASPPMSPSA--------TPPP---QAPPPLAAPPLQLAKPPPQAPPA-LATP--PLQ 529
+ + S +P P P PP + P P L++P P++
Sbjct: 773 EDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVE 832
Query: 530 A--LPSPPASFPG--QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT--- 582
A LP SF G +P + + P SP P P A L+ + +PP +P+
Sbjct: 833 ASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVN 892
Query: 583 LQAPRR-PPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEE 641
L P+ P TP P P L++ + + +P + P G + +TP
Sbjct: 893 LPFPKEGPATPAPK---QAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPS 949
Query: 642 LRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSAD 701
+G + P A +PP A P + GPA P + +GAP P PP+ G A
Sbjct: 950 PKGGPATPSPKWAPTPP------AATPPSPKGGPATP-SPKGAPTPPAATPPSPKGGPA- 1001
Query: 702 GLCTIYETEGPESATPAPGALDPGP--SPGTSGGKAAAGAGAGASSRSPKQARLG-ELPL 758
T P+ A P P P SP + A A+ SPK + LP
Sbjct: 1002 -------TPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPK 1054
Query: 759 GA 760
GA
Sbjct: 1055 GA 1056
Score = 94.7 bits (234), Expect = 3e-19
Identities = 159/643 (24%), Positives = 240/643 (37%), Gaps = 111/643 (17%)
Query: 151 PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVS 210
P SALS A GPT P ++ + P P+PS P E P S
Sbjct: 27 PMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSS 86
Query: 211 SASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS 270
S T P A P+ L P +S +A L+SP P+ +GTP + A
Sbjct: 87 S----GTALPLGTAPEAPTFLPNLIGP---PISPAALALASP-MIAPTLKGTPSSSA--- 135
Query: 271 QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSL 330
P L AL P V +K +A L+S P + S ++ + + P P+ P ++L
Sbjct: 136 ---PLALVALAPHSV---QKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEP-KTNL 188
Query: 331 TCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGS--PTLQATHSFLPSPPLSP 388
+ +P +PS P + T+P TP + + + S T T + SP +
Sbjct: 189 NKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKD 248
Query: 389 LATP----PPQAPPALALPPLQAPPSPPASPPLS----PLATPS---------PQAPNAL 431
PQ P +L+ L+ P SPPA+ LS P+ T S P P +L
Sbjct: 249 TTISSVLISPQNPGSLS---LKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISL 305
Query: 432 AVHLL---QAPF--------------SPPPSPPVQAPFSPP-ASPPVSPSATPP-----S 468
HL Q+ F S P + S AS P S PP
Sbjct: 306 GSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNE 365
Query: 469 QAPPSLAAPPLQVP-----PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP--- 520
P ++AA P+ P PS +S SPS + L+ + K P A
Sbjct: 366 VVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHY 425
Query: 521 PALATPPLQALPSPP--ASFPGQAPFSPSASLPMSPLATPPPQAPPV-----------LA 567
P +A P+ ++ + P + P +P+ + ++ +PP + P+ +
Sbjct: 426 PLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVM 485
Query: 568 APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP-------------GPPPP 614
AP+ PS + TL+ P PP P P+ + P L P G P
Sbjct: 486 APVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFS 545
Query: 615 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 674
P+++ +T P + +A + S PE P+A L A S G
Sbjct: 546 PAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPE----IPLSPEATL-----AKKSLG 596
Query: 675 PAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP 717
P+ G P + + P G S+ + GP+SA P
Sbjct: 597 EPLPI---GKPASSMTSP--LGVNSSASVIKTDSYAGPDSAGP 634
Score = 79.3 bits (194), Expect = 1e-14
Identities = 103/370 (27%), Positives = 145/370 (39%), Gaps = 47/370 (12%)
Query: 346 SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL 405
+ P + Q LP P A +S S T P P L P +P PQ P A
Sbjct: 8 TVPATEQELPQPQAETAVLPMSSALSVTAALGQ---PGPTLPPPCSPAPQQCPLSAAN-- 62
Query: 406 QAPPSP-PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP-VQAPFSPPASPPVSPS 463
QA P P P++ +PL P PQ+ + A+ L AP +P P + P SP A SP
Sbjct: 63 QASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPM 122
Query: 464 ATPPSQAPPSLAAPPLQV---PPSPPASPPMSPS-ATPPPQAPPPLAAPPLQLAKP-PPQ 518
P + PS +AP V P S S P+ T PP + + L+ P P
Sbjct: 123 IAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPS 182
Query: 519 AP-------PALATPPLQALPSPPASFPGQAPF---SPSASL-----------PMSPLAT 557
P P+ P + PSPP P+ +P AS+ P + LA
Sbjct: 183 EPKTNLNKVPSEVVPNPKGTPSPPC-IVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAI 241
Query: 558 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 617
PQ + +L + P P S +L+ P PP ++ S P +T + P P
Sbjct: 242 ASPQVKDTTISSVL-ISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPD 300
Query: 618 SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPA- 676
P S G LA S+ + + L G G +A S P ++ H + + P+
Sbjct: 301 FPISL--GSHLAPLHQSSFGSVQLL-----GQTGPSALSDPTVKTISVDHSSTGASYPSQ 353
Query: 677 ----PPLAFR 682
PPL R
Sbjct: 354 RSVIPPLPSR 363
Score = 77.8 bits (190), Expect = 4e-14
Identities = 134/530 (25%), Positives = 198/530 (37%), Gaps = 77/530 (14%)
Query: 185 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP--SPAARRRPSAGGGLQRPASRSL 242
TE LP+P P + + + T P SPA ++ P + P
Sbjct: 12 TEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPS 71
Query: 243 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 302
+ ++TPL P S P A P P P + PP +S +
Sbjct: 72 TIASTPLEVPFPQSSSGTALPLGTA-PEAP------TFLPNLIGPP----------ISPA 114
Query: 303 PLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPP 362
LA SP A PTL TP SS+ +A S + PP+L T P A
Sbjct: 115 ALALASPMIA------PTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAE 168
Query: 363 SQATTSLGSPTL----QATHSFLPSPPL-SPLATPPP----QAPPALALPPL----QAPP 409
S + +L +P + + +PS + +P TP P P + P+
Sbjct: 169 SGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVA 228
Query: 410 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 469
S P + P + LA SPQ + +L +P P S ++ P SPPA+ +S + P
Sbjct: 229 SLPQTTPTTTLAIASPQVKDTTISSVLISP-QNPGSLSLKGPVSPPAALSLSTQSLPVVT 287
Query: 470 APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQ 529
+ A P PP P S + P Q+ + +QL P AL+ P ++
Sbjct: 288 SSQKTAGP--NTPPDFPIS--LGSHLAPLHQS----SFGSVQLL--GQTGPSALSDPTVK 337
Query: 530 AL----PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 585
+ S AS+P Q P LP P A + AP + PS +S T
Sbjct: 338 TISVDHSSTGASYPSQRSVIP--PLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITC-- 393
Query: 586 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHS-SSATSTPEELRG 644
+P +V+ + +L+P SP++T P +A SS +TP +
Sbjct: 394 -----SPSGSLNVA---TSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTN 445
Query: 645 YDSGPEGGAAASPPPDAELAACHPAAWSRG------PAPPLAFRGAPGAP 688
+ AA+P E+A C S G P P A AP AP
Sbjct: 446 PCT-----IAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAP 490
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 165 bits (417), Expect = 2e-40
Identities = 146/507 (28%), Positives = 187/507 (36%), Gaps = 68/507 (13%)
Query: 272 PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLT 331
P K + PP TP + P + P TPSP + PPT +P ++ T
Sbjct: 1391 PMDKCITTPSPPTTTP----SPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTT 1446
Query: 332 CQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH---SFLPSPPLSP 388
T P P S + P T PSPP T PS TT+ PT T + PSPP +
Sbjct: 1447 TPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTT 1506
Query: 389 LATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV 448
TPP LPP P SPP + +P P + PSPP
Sbjct: 1507 PITPPASTT---TLPPTTTP-SPPTTTTTTP-------------------PPTTTPSPPT 1543
Query: 449 QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA----SPPMSPSATPPPQAPPP 504
P +PP S P T PS P + PP PSPP SPP + TPPP P
Sbjct: 1544 TTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTP- 1602
Query: 505 LAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 564
+PP PP P +PP +PP S P + + S P + TPPP P
Sbjct: 1603 --SPPTTTTTTPP--PTTTPSPPTTTPITPPTSTTTLPP-TTTPSPPPTTTTTPPPTTTP 1657
Query: 565 VLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS 624
+P PSPP + T P P T+ P T P P PS SP +T +
Sbjct: 1658 ---SPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPS-SPITTTT 1713
Query: 625 GPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGA 684
P S+T+TP + P SPP P +
Sbjct: 1714 TP-------SSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTL------------PPTTTSS 1754
Query: 685 PGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP----SPGTSGGKAAAGAG 740
P P PP+ P + T T G LD G PG G
Sbjct: 1755 PLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCG 1814
Query: 741 AG-ASSRSPKQARLGELPLGALQASVV 766
G A++ S + ++P+G L +VV
Sbjct: 1815 PGWAANISCRATMYPDVPIGQLGQTVV 1841
Score = 163 bits (413), Expect = 6e-40
Identities = 128/408 (31%), Positives = 164/408 (40%), Gaps = 54/408 (13%)
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTL 321
TP P P P L PP TP + P + P TPSP + PPT
Sbjct: 1398 TPSPPTTTPSPPPTSTTTL-PPTTTP----SPPTTTTTTPPPTTTPSPPITTTTTPPPTT 1452
Query: 322 PATPHSSSLTCQLATPLPLAP---PSPS----APPSLQTLPSPPATPPSQATTSLGSPTL 374
+P S+ T T P P PSP +PP+ T PP T PS TT+ +P
Sbjct: 1453 TPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPA 1512
Query: 375 QAT---HSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS-PPLSPLATPSPQAPNA 430
T + PSPP + TPPP P+ PP P +PP S L P TPSP
Sbjct: 1513 STTTLPPTTTPSPPTTTTTTPPPTTTPS---PPTTTPITPPTSTTTLPPTTTPSPPPTTT 1569
Query: 431 LAVHLLQAPFSPP----PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 486
P SPP PSPP +PP + SP T + PP+ P P + P
Sbjct: 1570 TTPPPTTTP-SPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSP---PTTTP 1625
Query: 487 ASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP 546
+PP S + PP P P PP PPP P +PP PSPP + P
Sbjct: 1626 ITPPTSTTTLPPTTTPSP---PPTTTTTPPPTTTP---SPPTTTTPSPPIT---TTTTPP 1676
Query: 547 SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT-----LQAPRRPP----TPGPDTS 597
+ P SP+ T P + P PS P + T P PP TP P T+
Sbjct: 1677 PTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTT 1736
Query: 598 VSGPRLTLALAPGPPPPPSRSPSST------LSGPDLAGHSSSATSTP 639
S P T+ PP + SP +T ++ P + S++ +TP
Sbjct: 1737 PSPPTTTMTTL---PPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTP 1781
Score = 162 bits (410), Expect = 1e-39
Identities = 134/468 (28%), Positives = 180/468 (38%), Gaps = 70/468 (14%)
Query: 148 TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRK 207
T +P + S T+ P TPSP + P P+ P PP
Sbjct: 1398 TPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTT----------TPPPTTTPSPPI----- 1442
Query: 208 SVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPA 267
++ + TT PSP P S + + T SP + PS T +P
Sbjct: 1443 -TTTTTPPPTTTPSP--------------PISTTTTPPPTTTPSPPTTTPSPPTTTPSPP 1487
Query: 268 HPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS---PLATPSPSAALQSQAPP-TLPA 323
+ P PP TP P P S++ P TPSP + PP T P+
Sbjct: 1488 TTTTTTP-------PPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPS 1540
Query: 324 TPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQAT---HSF 380
P ++ +T +T +PS PP+ T P P TP TT+ PT+ T +
Sbjct: 1541 PPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTT 1600
Query: 381 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS-PPLSPLATPSPQAPNALAVHLLQAP 439
PSPP + TPPP P+ PP P +PP S L P TPSP
Sbjct: 1601 TPSPPTTTTTTPPPTTTPS---PPTTTPITPPTSTTTLPPTTTPSPPPTTTT-------- 1649
Query: 440 FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 499
+PPP+ P + SPP++ + TPP PS P+ PSPP + +PS T P
Sbjct: 1650 -TPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPS---SPITTTPSPPTTTMTTPSPTTTP 1705
Query: 500 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPP----ASFPGQAPFSPSASLPMSPL 555
+P P P P P + TP PSPP + P SP + P+ P
Sbjct: 1706 SSPITTTTTPSSTTTPSP-PPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPS 1764
Query: 556 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT---PGPDTSVSG 600
TPP +P P P P + T P PG DT + G
Sbjct: 1765 ITPPTFSPFSTTTP--TTPCVPLCNWTGWLDSGKPNFHKPGGDTELIG 1810
Score = 153 bits (387), Expect = 6e-37
Identities = 128/434 (29%), Positives = 166/434 (38%), Gaps = 66/434 (15%)
Query: 198 PRPPTEGPRKSVSSASE-HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG 256
P PPT P +S + TT PSP +++ TP + S
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPT------------------TTTTTPPPTTTPSP 1440
Query: 257 PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQ 316
P T P P P PP TP P S P TPSP +
Sbjct: 1441 PITTTTTPPPTTTPSP-PISTTTTPPPTTTPSPPTTTP------SPPTTTPSPPTTTTTT 1493
Query: 317 APPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQA 376
PPT +P +++ A+ L P + +PP+ T PP T PS TT+ +P
Sbjct: 1494 PPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTST 1553
Query: 377 TH---SFLPSPP-LSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALA 432
T + PSPP + TPPP P+ PP PSPP +P T +P P
Sbjct: 1554 TTLPPTTTPSPPPTTT-TTPPPTTTPS---PPTTTTPSPPTITTTTPPPTTTPSPPTTTT 1609
Query: 433 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA----S 488
P + PSPP P +PP S P T PS P + PP PSPP S
Sbjct: 1610 T---TPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPS 1666
Query: 489 PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 548
PP++ + TPPP P + P+ PP + TP PS P + +
Sbjct: 1667 PPITTTTTPPPTTTP---SSPITTTPSPPTT--TMTTPSPTTTPSSPIT---------TT 1712
Query: 549 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALA 608
+ P S PP P + P PSPP + T P T+ S P T L
Sbjct: 1713 TTPSSTTTPSPP--PTTMTTPSPTTTPSPPTTTM--------TTLPPTTTSSPLTTTPLP 1762
Query: 609 PGPPPPPSRSPSST 622
P PP+ SP ST
Sbjct: 1763 PS-ITPPTFSPFST 1775
Score = 138 bits (348), Expect = 2e-32
Identities = 126/483 (26%), Positives = 172/483 (35%), Gaps = 101/483 (20%)
Query: 24 LLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSA 83
+ TP PP + PPP + T+P + + PT +
Sbjct: 1396 ITTPSPPTTTPSPPPTSTT--------------------------TLPPTTTPSPPTTTT 1429
Query: 84 GTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVA 143
T PP + PP T P+S+ TT P P
Sbjct: 1430 TTPPPTTTPSPPITTT--TTPPPTTTPSPPISTTTTPPPTTTPSP--------------- 1472
Query: 144 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE 203
T +P + S T+ P TPSP + LP P+ P PPT
Sbjct: 1473 -PTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLP---PTTTPSPPTT 1528
Query: 204 GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS-RSLSSSATPLSSPARSGPSARGT 262
+TT P P P + P S +L + TP P + T
Sbjct: 1529 ------------TTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTT 1576
Query: 263 PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLP 322
+P + P P + PP T P + P + P TPSP P T P
Sbjct: 1577 TPSPPTTTTPSPPTITTTTPPPTTTP---SPPTTTTTTPPPTTTPSP--------PTTTP 1625
Query: 323 ATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLP 382
TP +S+ T T +PS PP+ T P PP T PS TT+ P
Sbjct: 1626 ITPPTSTTTLPPTT-------TPSPPPTTTTTP-PPTTTPSPPTTT------------TP 1665
Query: 383 SPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS- 441
SPP++ TPPP P+ P+ PSPP + +P T +P +P + P S
Sbjct: 1666 SPPITTTTTPPPTTTPS---SPITTTPSPPTTTMTTPSPTTTPSSP----ITTTTTPSST 1718
Query: 442 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA--SPPMSPSATPPP 499
PSPP +P + SP T + PP+ + PL P PP+ P SP +T P
Sbjct: 1719 TTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTP 1778
Query: 500 QAP 502
P
Sbjct: 1779 TTP 1781
Score = 113 bits (282), Expect = 9e-25
Identities = 154/754 (20%), Positives = 245/754 (32%), Gaps = 84/754 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 3609 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 3661
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 3662 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3721
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3722 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3775
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3776 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3832
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3833 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3889
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3890 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3944
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3945 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 4001
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 4002 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4060
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 4061 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 4120
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSPPAS------PTLQ 584
P + P P + + ++ +P T P P+ + P+P + P
Sbjct: 4121 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4180
Query: 585 APRRPPTPGPDTSVSGPRLTLALAP------GPPPPPSRSPSSTLSGPDLAGHSSSATST 638
PTP P + +GP + AP PPP S +P ++ S S++ ST
Sbjct: 4181 TTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLST 4240
Query: 639 PEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPG 698
P ++ PP A + PP PG P TG
Sbjct: 4241 --------LPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTR-GTTTGSS 4291
Query: 699 SADGLCTIYETEGPESATPAPGALDPGPSPGTSG 732
SA T+ +T + TP P L T+G
Sbjct: 4292 SAPTPSTV-QTTTTSAWTPTPTPLSTPSIIRTTG 4324
Score = 105 bits (263), Expect = 1e-22
Identities = 144/668 (21%), Positives = 217/668 (32%), Gaps = 139/668 (20%)
Query: 22 PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81
P TP PP + PP TP S P T
Sbjct: 1465 PPTTTPSPPTTTPSPPTTTP-------------------------------SPPTTTTTT 1493
Query: 82 SAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEET 141
T++ +P + P + PPA T+ P ++P + TT P +
Sbjct: 1494 PPPTTTPSPPTTTPIT------PPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1547
Query: 142 VARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 201
T P + S T+ P TPSP + + + P P+ P PP
Sbjct: 1548 TPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTT--TTPSPPTITTTTPPPTTTPSPP 1605
Query: 202 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS-RSLSSSATPLSSPARSGPSAR 260
T +TT P P P + P S +L + TP P +
Sbjct: 1606 TT------------TTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPP 1653
Query: 261 GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL-ATPS-PSAALQSQAP 318
T +P + P P PP T P SSP+ TPS P+ + + +P
Sbjct: 1654 TTTPSPPTTTTPSPPITTTTTPPPTTTP------------SSPITTTPSPPTTTMTTPSP 1701
Query: 319 PTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH 378
T P++P +++ T P + +PS PP+ T PS P T PS TT++ + T
Sbjct: 1702 TTTPSSPITTTTT-------PSSTTTPSPPPTTMTTPS-PTTTPSPPTTTMTTLPPTTTS 1753
Query: 379 SFLPSPPLSPLATPPPQAPPALALPPLQAPP----------------------------- 409
S L + PL P TPP +P + P P
Sbjct: 1754 SPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVC 1813
Query: 410 SPPASPPLSPLATPSPQAPNA---------LAVHLLQAPFSPPPSPPVQAPF-------- 452
P + +S AT P P ++V L+ P + F
Sbjct: 1814 GPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINV 1873
Query: 453 ---SPPASPPVSPSATPPSQAPPSLA--APPLQVPPSPPASPPMSPSATPPPQAPPPLAA 507
P + T + PP+ V P+P + +P+ T P +
Sbjct: 1874 QCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTT-PITTTTTVTP 1932
Query: 508 PPLQLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPF--------SPSASLPMSPLATP 558
P P P T + P+P + P P +P+ + +P TP
Sbjct: 1933 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 1992
Query: 559 PPQAPPVLAAPL---LQVPPSPPASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPP 614
V P Q P + P + T P G T + P T + P P P
Sbjct: 1993 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2052
Query: 615 PSRSPSST 622
+++P++T
Sbjct: 2053 GTQTPTTT 2060
Score = 103 bits (256), Expect = 9e-22
Identities = 129/651 (19%), Positives = 212/651 (32%), Gaps = 68/651 (10%)
Query: 16 TPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAP 75
TP P T +P P TP + P G T P +
Sbjct: 1894 TPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT---PTPTPTGTQTPTTTPITTT 1950
Query: 76 RAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR 135
T ++ P + P + P + P ++P + T P P
Sbjct: 1951 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2010
Query: 136 ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPS 195
+ T P + + T TP+P GT+ P +
Sbjct: 2011 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITT 2064
Query: 196 ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 255
PT P + + + TT + P+ G Q P + ++++ T +P +
Sbjct: 2065 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPT 2121
Query: 256 G---PSARGTPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLS 300
G P+ P P G Q P TP P P P++
Sbjct: 2122 GTQTPTTTPITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2178
Query: 301 SSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPAT 360
++ TP+P+ +Q P T P T + T TP P +P+ P T P
Sbjct: 2179 TTTTVTPTPTPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2233
Query: 361 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASP 415
P+ T +P + T + P+P +P T P P + P+P P +
Sbjct: 2234 TPTGTQTPTTTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2290
Query: 416 PLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSAT 465
P++ T +P Q P + +P P+P Q P + P + V+P+ T
Sbjct: 2291 PITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2349
Query: 466 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALA 524
P P+ +P +P + + T P P P P P
Sbjct: 2350 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2409
Query: 525 TPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---- 577
T + P+P + P P + + ++ +P T P P+ + P+P
Sbjct: 2410 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2469
Query: 578 -----PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
P + T P G T + P T + P P P +++P++T
Sbjct: 2470 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2520
Score = 103 bits (256), Expect = 9e-22
Identities = 155/796 (19%), Positives = 249/796 (31%), Gaps = 97/796 (12%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 3471 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 3523
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 3524 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3583
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3584 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3637
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3638 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3694
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3695 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3751
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3752 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3806
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3807 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3863
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3864 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3922
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3923 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3982
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3983 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4042
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST----------------LS 624
T P G T + P T + P P P +++P++T
Sbjct: 4043 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 4102
Query: 625 GPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGA 684
P +++ T TP P G + P P G P
Sbjct: 4103 TPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4156
Query: 685 PGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAA--AGAGAG 742
+ P T G+ T T + TP P GP TS A +
Sbjct: 4157 TTTTVT-PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPP 4215
Query: 743 ASSRSPKQARLGELPL 758
S +P+ +R PL
Sbjct: 4216 PESSTPQTSRSTSSPL 4231
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 1930 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 1982
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 1983 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2042
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2043 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2096
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2097 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2153
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2154 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2210
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2211 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2265
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2266 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2322
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2323 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2381
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 2382 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2441
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 2442 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2501
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 2502 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2543
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 1953 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2005
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2006 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2065
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2066 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2119
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2120 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2176
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2177 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2233
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2234 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2288
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2289 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2345
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2346 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2404
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 2405 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2464
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 2465 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2524
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 2525 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2566
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 1976 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2028
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2029 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2088
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2089 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2142
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2143 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2199
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2200 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2256
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2257 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2311
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2312 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2368
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2369 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2427
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 2428 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2487
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 2488 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2547
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 2548 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2589
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 1999 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2051
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2052 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2111
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2112 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2165
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2166 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2222
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2223 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2279
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2280 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2334
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2335 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2391
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2392 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2450
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 2451 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2510
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 2511 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2570
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 2571 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2612
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2022 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2074
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2075 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2134
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2135 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2188
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2189 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2245
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2246 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2302
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2303 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2357
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2358 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2414
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2415 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2473
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 2474 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2533
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 2534 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2593
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 2594 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2635
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2045 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2097
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2098 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2157
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2158 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2211
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2212 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2268
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2269 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2325
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2326 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2380
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2381 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2437
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2438 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2496
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 2497 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2556
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 2557 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2616
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 2617 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2658
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2068 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2120
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2121 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2180
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2181 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2234
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2235 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2291
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2292 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2348
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2349 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2403
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2404 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2460
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2461 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2519
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 2520 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2579
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 2580 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2639
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 2640 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2681
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2091 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2143
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2144 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2203
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2204 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2257
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2258 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2314
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2315 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2371
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2372 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2426
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2427 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2483
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2484 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2542
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 2543 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2602
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 2603 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2662
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 2663 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2704
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2114 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2166
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2167 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2226
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2227 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2280
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2281 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2337
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2338 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2394
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2395 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2449
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2450 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2506
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2507 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2565
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 2566 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2625
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 2626 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2685
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 2686 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2727
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2137 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2189
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2190 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2249
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2250 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2303
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2304 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2360
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2361 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2417
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2418 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2472
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2473 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2529
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2530 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2588
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 2589 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2648
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 2649 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2708
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 2709 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2750
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2160 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2212
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2213 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2272
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2273 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2326
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2327 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2383
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2384 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2440
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2441 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2495
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2496 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2552
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2553 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2611
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 2612 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2671
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 2672 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2731
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 2732 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2773
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2183 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2235
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2236 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2295
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2296 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2349
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2350 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2406
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2407 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2463
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2464 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2518
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2519 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2575
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2576 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2634
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 2635 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2694
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 2695 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2754
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 2755 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2796
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2206 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2258
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2259 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2318
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2319 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2372
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2373 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2429
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2430 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2486
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2487 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2541
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2542 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2598
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2599 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2657
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 2658 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2717
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 2718 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2777
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 2778 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2819
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2229 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2281
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2282 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2341
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2342 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2395
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2396 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2452
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2453 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2509
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2510 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2564
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2565 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2621
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2622 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2680
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 2681 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2740
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 2741 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2800
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 2801 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2842
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2252 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2304
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2305 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2364
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2365 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2418
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2419 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2475
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2476 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2532
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2533 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2587
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2588 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2644
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2645 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2703
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 2704 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2763
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 2764 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2823
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 2824 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2865
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2275 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2327
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2328 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2387
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2388 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2441
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2442 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2498
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2499 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2555
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2556 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2610
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2611 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2667
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2668 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2726
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 2727 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2786
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 2787 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2846
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 2847 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2888
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2298 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2350
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2351 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2410
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2411 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2464
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2465 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2521
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2522 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2578
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2579 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2633
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2634 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2690
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2691 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2749
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 2750 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2809
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 2810 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2869
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 2870 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2911
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2321 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2373
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2374 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2433
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2434 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2487
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2488 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2544
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2545 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2601
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2602 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2656
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2657 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2713
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2714 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2772
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 2773 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2832
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 2833 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2892
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 2893 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2934
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2344 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2396
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2397 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2456
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2457 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2510
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2511 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2567
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2568 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2624
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2625 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2679
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2680 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2736
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2737 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2795
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 2796 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2855
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 2856 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2915
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 2916 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2957
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2367 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2419
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2420 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2479
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2480 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2533
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2534 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2590
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2591 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2647
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2648 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2702
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2703 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2759
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2760 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2818
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 2819 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2878
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 2879 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2938
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 2939 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2980
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2390 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2442
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2443 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2502
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2503 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2556
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2557 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2613
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2614 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2670
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2671 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2725
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2726 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2782
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2783 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2841
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 2842 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2901
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 2902 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2961
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 2962 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3003
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2413 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2465
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2466 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2525
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2526 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2579
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2580 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2636
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2637 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2693
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2694 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2748
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2749 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2805
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2806 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2864
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 2865 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2924
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 2925 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2984
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 2985 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3026
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2436 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2488
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2489 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2548
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2549 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2602
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2603 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2659
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2660 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2716
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2717 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2771
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2772 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2828
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2829 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2887
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 2888 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2947
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 2948 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3007
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3008 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3049
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2459 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2511
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2512 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2571
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2572 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2625
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2626 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2682
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2683 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2739
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2740 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2794
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2795 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2851
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2852 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2910
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 2911 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2970
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 2971 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3030
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3031 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3072
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2482 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2534
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2535 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2594
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2595 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2648
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2649 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2705
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2706 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2762
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2763 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2817
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2818 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2874
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2875 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2933
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 2934 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2993
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 2994 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3053
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3054 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3095
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2505 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2557
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2558 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2617
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2618 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2671
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2672 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2728
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2729 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2785
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2786 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2840
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2841 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2897
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2898 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2956
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 2957 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3016
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3017 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3076
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3077 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3118
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2528 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2580
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2581 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2640
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2641 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2694
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2695 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2751
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2752 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2808
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2809 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2863
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2864 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2920
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2921 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2979
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 2980 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3039
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3040 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3099
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3100 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3141
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2551 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2603
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2604 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2663
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2664 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2717
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2718 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2774
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2775 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2831
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2832 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2886
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2887 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2943
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2944 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3002
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3003 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3062
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3063 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3122
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3123 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3164
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2574 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2626
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2627 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2686
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2687 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2740
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2741 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2797
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2798 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2854
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2855 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2909
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2910 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2966
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2967 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3025
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3026 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3085
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3086 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3145
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3146 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3187
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2597 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2649
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2650 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2709
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2710 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2763
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2764 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2820
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2821 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2877
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2878 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2932
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2933 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2989
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 2990 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3048
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3049 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3108
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3109 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3168
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3169 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3210
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2620 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2672
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2673 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2732
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2733 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2786
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2787 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2843
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2844 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2900
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2901 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2955
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2956 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3012
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3013 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3071
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3072 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3131
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3132 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3191
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3192 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3233
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2643 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2695
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2696 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2755
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2756 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2809
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2810 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2866
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2867 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2923
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2924 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2978
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 2979 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3035
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3036 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3094
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3095 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3154
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3155 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3214
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3215 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3256
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2666 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2718
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2719 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2778
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2779 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2832
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2833 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2889
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2890 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2946
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2947 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3001
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3002 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3058
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3059 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3117
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3118 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3177
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3178 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3237
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3238 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3279
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2689 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2741
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2742 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2801
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2802 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2855
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2856 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2912
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2913 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2969
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2970 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3024
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3025 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3081
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3082 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3140
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3141 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3200
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3201 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3260
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3261 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3302
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2712 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2764
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2765 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2824
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2825 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2878
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2879 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2935
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2936 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2992
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 2993 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3047
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3048 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3104
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3105 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3163
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3164 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3223
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3224 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3283
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3284 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3325
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2735 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2787
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2788 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2847
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2848 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2901
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2902 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2958
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2959 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3015
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3016 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3070
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3071 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3127
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3128 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3186
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3187 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3246
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3247 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3306
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3307 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3348
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2758 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2810
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2811 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2870
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2871 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2924
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2925 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2981
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 2982 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3038
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3039 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3093
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3094 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3150
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3151 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3209
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3210 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3269
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3270 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3329
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3330 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3371
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2781 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2833
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2834 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2893
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2894 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2947
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2948 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3004
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3005 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3061
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3062 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3116
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3117 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3173
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3174 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3232
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3233 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3292
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3293 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3352
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3353 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3394
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2804 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2856
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2857 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2916
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2917 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2970
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2971 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3027
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3028 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3084
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3085 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3139
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3140 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3196
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3197 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3255
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3256 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3315
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3316 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3375
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3376 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3417
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2827 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2879
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2880 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2939
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2940 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 2993
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 2994 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3050
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3051 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3107
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3108 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3162
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3163 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3219
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3220 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3278
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3279 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3338
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3339 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3398
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3399 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3440
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2850 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2902
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2903 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2962
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2963 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3016
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3017 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3073
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3074 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3130
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3131 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3185
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3186 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3242
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3243 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3301
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3302 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3361
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3362 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3421
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3422 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3463
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2873 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2925
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2926 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2985
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 2986 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3039
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3040 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3096
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3097 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3153
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3154 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3208
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3209 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3265
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3266 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3324
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3325 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3384
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3385 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3444
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3445 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3486
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2896 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2948
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2949 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3008
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3009 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3062
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3063 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3119
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3120 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3176
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3177 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3231
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3232 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3288
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3289 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3347
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3348 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3407
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3408 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3467
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3468 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3509
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2919 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2971
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2972 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3031
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3032 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3085
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3086 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3142
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3143 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3199
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3200 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3254
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3255 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3311
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3312 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3370
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3371 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3430
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3431 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3490
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3491 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3532
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2942 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 2994
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 2995 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3054
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3055 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3108
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3109 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3165
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3166 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3222
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3223 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3277
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3278 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3334
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3335 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3393
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3394 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3453
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3454 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3513
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3514 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3555
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2965 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 3017
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 3018 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3077
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3078 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3131
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3132 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3188
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3189 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3245
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3246 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3300
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3301 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3357
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3358 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3416
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3417 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3476
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3477 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3536
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3537 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3578
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 2988 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 3040
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 3041 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3100
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3101 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3154
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3155 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3211
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3212 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3268
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3269 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3323
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3324 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3380
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3381 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3439
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3440 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3499
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3500 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3559
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3560 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3601
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 3011 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 3063
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 3064 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3123
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3124 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3177
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3178 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3234
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3235 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3291
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3292 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3346
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3347 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3403
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3404 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3462
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3463 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3522
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3523 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3582
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3583 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3624
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 3034 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 3086
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 3087 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3146
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3147 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3200
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3201 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3257
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3258 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3314
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3315 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3369
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3370 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3426
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3427 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3485
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3486 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3545
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3546 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3605
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3606 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3647
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 3057 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 3109
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 3110 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3169
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3170 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3223
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3224 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3280
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3281 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3337
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3338 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3392
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3393 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3449
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3450 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3508
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3509 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3568
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3569 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3628
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3629 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3670
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 3080 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 3132
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 3133 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3192
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3193 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3246
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3247 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3303
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3304 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3360
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3361 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3415
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3416 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3472
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3473 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3531
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3532 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3591
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3592 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3651
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3652 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3693
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 3103 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 3155
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 3156 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3215
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3216 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3269
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3270 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3326
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3327 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3383
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3384 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3438
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3439 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3495
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3496 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3554
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3555 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3614
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3615 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3674
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3675 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3716
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 3126 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 3178
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 3179 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3238
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3239 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3292
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3293 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3349
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3350 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3406
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3407 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3461
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3462 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3518
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3519 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3577
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3578 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3637
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3638 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3697
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3698 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3739
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 3149 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 3201
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 3202 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3261
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3262 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3315
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3316 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3372
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3373 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3429
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3430 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3484
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3485 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3541
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3542 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3600
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3601 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3660
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3661 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3720
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3721 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3762
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 3172 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 3224
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 3225 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3284
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3285 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3338
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3339 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3395
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3396 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3452
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3453 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3507
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3508 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3564
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3565 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3623
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3624 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3683
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3684 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3743
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3744 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3785
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 3195 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 3247
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 3248 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3307
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3308 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3361
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3362 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3418
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3419 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3475
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3476 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3530
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3531 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3587
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3588 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3646
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3647 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3706
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3707 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3766
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3767 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3808
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 3218 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 3270
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 3271 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3330
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3331 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3384
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3385 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3441
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3442 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3498
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3499 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3553
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3554 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3610
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3611 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3669
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3670 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3729
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3730 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3789
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3790 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3831
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 3241 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 3293
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 3294 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3353
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3354 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3407
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3408 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3464
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3465 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3521
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3522 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3576
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3577 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3633
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3634 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3692
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3693 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3752
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3753 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3812
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3813 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3854
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 3264 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 3316
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 3317 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3376
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3377 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3430
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3431 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3487
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3488 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3544
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3545 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3599
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3600 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3656
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3657 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3715
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3716 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3775
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3776 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3835
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3836 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3877
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 3287 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 3339
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 3340 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3399
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3400 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3453
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3454 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3510
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3511 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3567
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3568 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3622
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3623 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3679
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3680 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3738
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3739 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3798
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3799 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3858
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3859 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3900
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 3310 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 3362
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 3363 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3422
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3423 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3476
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3477 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3533
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3534 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3590
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3591 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3645
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3646 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3702
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3703 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3761
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3762 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3821
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3822 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3881
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3882 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3923
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 3333 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 3385
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 3386 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3445
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3446 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3499
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3500 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3556
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3557 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3613
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3614 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3668
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3669 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3725
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3726 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3784
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3785 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3844
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3845 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3904
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3905 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3946
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 3356 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 3408
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 3409 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3468
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3469 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3522
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3523 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3579
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3580 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3636
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3637 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3691
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3692 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3748
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3749 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3807
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3808 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3867
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3868 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3927
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3928 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3969
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 3379 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 3431
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 3432 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3491
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3492 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3545
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3546 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3602
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3603 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3659
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3660 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3714
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3715 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3771
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3772 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3830
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3831 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3890
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3891 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3950
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3951 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3992
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 3402 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 3454
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 3455 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3514
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3515 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3568
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3569 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3625
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3626 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3682
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3683 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3737
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3738 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3794
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3795 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3853
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3854 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3913
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3914 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3973
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3974 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4015
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 3425 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 3477
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 3478 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3537
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3538 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3591
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3592 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3648
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3649 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3705
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3706 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3760
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3761 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3817
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3818 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3876
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3877 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3936
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3937 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3996
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 3997 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4038
Score = 101 bits (251), Expect = 3e-21
Identities = 127/642 (19%), Positives = 210/642 (32%), Gaps = 72/642 (11%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 3448 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 3500
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 3501 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3560
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3561 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 3614
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 3615 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3671
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 3672 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3728
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 3729 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3783
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPS 424
+P + T + P+P +P T P P + P+P P + P++ T +
Sbjct: 3784 TTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3840
Query: 425 P-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSL 474
P Q P + +P P+P Q P + P + V+P+ TP P+
Sbjct: 3841 PTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 3899
Query: 475 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPS 533
+P +P + + T P P P P P T + P+
Sbjct: 3900 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3959
Query: 534 PPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---------PASP 581
P + P P + + ++ +P T P P+ + P+P P +
Sbjct: 3960 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4019
Query: 582 TLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
T P G T + P T + P P P +++P++T
Sbjct: 4020 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4061
Score = 100 bits (249), Expect = 6e-21
Identities = 120/591 (20%), Positives = 200/591 (33%), Gaps = 68/591 (11%)
Query: 79 PTRSAGTSSRNPA---SRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR 135
PT T++ NP + P + P + P ++P + T P P
Sbjct: 1882 PTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 1941
Query: 136 ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPS 195
+ T P + + T TP+P GT+ P +
Sbjct: 1942 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITT 1995
Query: 196 ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 255
PT P + + + TT + P+ G Q P + ++++ T +P +
Sbjct: 1996 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPT 2052
Query: 256 G---PSARGTPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLS 300
G P+ P P G Q P TP P P P++
Sbjct: 2053 GTQTPTTTPITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2109
Query: 301 SSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPAT 360
++ TP+P+ +Q P T P T + T TP P +P+ P T P
Sbjct: 2110 TTTTVTPTPTPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2164
Query: 361 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASP 415
P+ T +P + T + P+P +P T P P + P+P P +
Sbjct: 2165 TPTGTQTPTTTP-ITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2221
Query: 416 PLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSAT 465
P++ T +P Q P + +P P+P Q P + P + V+P+ T
Sbjct: 2222 PITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2280
Query: 466 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALA 524
P P+ +P +P + + T P P P P P
Sbjct: 2281 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2340
Query: 525 TPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP---- 577
T + P+P + P P + + ++ +P T P P+ + P+P
Sbjct: 2341 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2400
Query: 578 -----PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 622
P + T P G T + P T + P P P +++P++T
Sbjct: 2401 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2451
Score = 90.9 bits (224), Expect = 5e-18
Identities = 141/682 (20%), Positives = 225/682 (32%), Gaps = 96/682 (14%)
Query: 16 TPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAP 75
TP+ TP P +P PP TP+ + P T P +
Sbjct: 1561 TPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTT---TTTTPPPTTT 1617
Query: 76 RAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR 135
+ PT + T + + PP + PP T+P P ++P + TT P+
Sbjct: 1618 PSPPTTTPITPPTSTTTLPPTT--TPSPPPTTTTTPPPTTTPSPPTTTTPSPPI------ 1669
Query: 136 ISAEETVARGKATEAPKRSALSAGARRDTSGPTPG---TPSPAMARRSRAAGTEVGLP-- 190
T T P + + T+ TP TPS + + + T P
Sbjct: 1670 ----TTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPP 1725
Query: 191 ----RPAPSARPRPPTEG----PRKSVSSA---------------SEHSTTEPSPAARRR 227
P+P+ P PPT P + SS S STT P+
Sbjct: 1726 TTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPL 1785
Query: 228 PSAGGGLQ--RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL----- 280
+ G L +P + G +A + RA +P P + Q +
Sbjct: 1786 CNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVS 1845
Query: 281 ----------RPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSL 330
+P V P + + P+ ++ P T P T ++
Sbjct: 1846 VGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENP-TPPTTTPITTT 1904
Query: 331 TCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA 390
T TP P +P+ P T P P+ T +P + T + P+P +P
Sbjct: 1905 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTP--TPTG 1961
Query: 391 TPPPQAPPALALPPLQAPPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQA 438
T P P + P+P P + P++ T +P Q P +
Sbjct: 1962 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTT 2020
Query: 439 PFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSLA--APPLQVPPSPPASPPMSP 493
+P P+P Q P + P + V+P+ TP P+ V P+P + +P
Sbjct: 2021 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2080
Query: 494 SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPF-------- 544
+ T P + P P P T + P+P + P P
Sbjct: 2081 TTT-PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2139
Query: 545 SPSASLPMSPLATPPPQAPPVLAAPL---LQVPPSPPASPTLQAPRRPPTPGPDTSVSGP 601
+P+ + +P TP V P Q P + P + T P G T + P
Sbjct: 2140 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2199
Query: 602 -RLTLALAPGPPPPPSRSPSST 622
T + P P P +++P++T
Sbjct: 2200 ITTTTTVTPTPTPTGTQTPTTT 2221
Score = 89.4 bits (220), Expect = 1e-17
Identities = 128/620 (20%), Positives = 196/620 (31%), Gaps = 93/620 (15%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 3839 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 3891
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 3892 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3951
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 3952 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 4005
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 4006 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4062
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 4063 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4119
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ +Q P T P T + T TP P +P+ P T P P+ T
Sbjct: 4120 TPT-GTQTPTTTPIT----TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 4174
Query: 370 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL-QAPPSPPASPPLSPLATPSPQAP 428
+P + T + P+P + T PP + L + P P +S P + +T SP
Sbjct: 4175 TTP-ITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTE 4233
Query: 429 NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 488
+ + L P ++ + P S P +P+ T L PPS S
Sbjct: 4234 STTLLSTL--------PPAIEMTSTAPPSTPTAPTTTSGGHT--------LSPPPSTTTS 4277
Query: 489 PPMSP--------SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPS------- 533
PP +P S+ P P P P + T L+ PS
Sbjct: 4278 PPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCV 4337
Query: 534 --PPASFPGQAPF-------------SPSASLPM---SPLATPPPQAPPVLAAPLLQVPP 575
PG+ + S S +L S +TP P P + P P
Sbjct: 4338 LNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPS 4397
Query: 576 SPPASPTLQAPRRPPTPGPD 595
S P+ PT P P PD
Sbjct: 4398 STPSKPT---PGTKPPECPD 4414
Score = 83.2 bits (204), Expect = 9e-16
Identities = 112/533 (21%), Positives = 176/533 (33%), Gaps = 77/533 (14%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
+TP P + P TP P G T P +
Sbjct: 3908 VTPTPTPTGTQTPTTTPITTTTTVT-------PTPTPTGTQTPTTTPITTTTTVTPTPTP 3960
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 144
T ++ P + P + P + P ++P + T P P +
Sbjct: 3961 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 4020
Query: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204
T P + + T TP+P GT+ P + PT
Sbjct: 4021 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPT 4074
Query: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARG 261
P + + + TT + P+ G Q P + ++++ T +P +G P+
Sbjct: 4075 PTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4131
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSP 309
P P G Q P TP P P P++++ TP+P
Sbjct: 4132 ITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4188
Query: 310 SAALQSQAPPTLPAT------------PHSSSLTCQLATPLPLAPPSP---SAPPSLQ-T 353
+ PPT +T P SS+ +T PL + + PP+++ T
Sbjct: 4189 TPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMT 4248
Query: 354 LPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPA 413
+PP+TP + TTS G TL S SPP +P + A +Q +
Sbjct: 4249 STAPPSTPTAPTTTS-GGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAW 4307
Query: 414 SPPLSPLATPS--------PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA--------- 456
+P +PL+TPS P + L +L + P +
Sbjct: 4308 TPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSC 4367
Query: 457 -------SPPVSPSATP-PSQAPPSLAAPP-LQVPPSPPASPPMSPSATPPPQ 500
S P +PS TP PS++ P+ + P P+P PP P PP Q
Sbjct: 4368 TLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQ 4420
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 153 bits (387), Expect = 6e-37
Identities = 239/837 (28%), Positives = 315/837 (37%), Gaps = 151/837 (18%)
Query: 17 PAARAPG--LLTPRPP-----------------GSPRPPPPV-----TPAALRVLGAAGA 52
PA+R PG LL P P G+ RPP P TP A L A
Sbjct: 1062 PASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPP 1121
Query: 53 VGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGR-------GERAPP 105
G L + G T P +A T +A ++ + PA R R P
Sbjct: 1122 PGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPS 1181
Query: 106 AKNTSPGPVSS----PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKR------SA 155
+ S G ++S P +G ++P +G +++ R A P+
Sbjct: 1182 GEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHL 1241
Query: 156 LSAGARRD----------------TSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 199
+SAG + T GPTP + P+ + A T + LP A
Sbjct: 1242 VSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQV--- 1298
Query: 200 PPT----EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS--SATPLSSPA 253
PPT G K V + P P P RP S L + + P +P
Sbjct: 1299 PPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAP-------RPPSSGLPAVLNPRPTLTPG 1351
Query: 254 RSGPSARGTPRAPAH-PSQPKPKGLQALRP-PQVTPPRKDAAPAL------------GPL 299
R GT RAP P+ +P P P+V+ AAP GP
Sbjct: 1352 RLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPA 1411
Query: 300 SS-------SPLATPSPS-------AALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSP 345
SS SPLA+P S ++L P TLPA P S+ LT ++ PL ++ P
Sbjct: 1412 SSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPA-PASAPLTIPISAPLTVSASGP 1470
Query: 346 S-----APPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ---AP 397
+ PP +P+ P PPS A + T +P LS TP AP
Sbjct: 1471 ALLTSVTPPLAPVVPAAPG-PPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAP 1529
Query: 398 PALALPPLQAPPSPPASP---PLSPLATPSPQAPN-ALAVHLLQAPFSPPPSPPVQAPFS 453
+ +P L + +P SP P S LA+P P APN A A L AP S S + P +
Sbjct: 1530 TSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPAS-SASQALATPLA 1588
Query: 454 PPASPP---VSPSATPPSQAPPSLAAPPLQVP---PSPPASPPMSPSATP--------PP 499
P A+P ++PS PP P LA P P S P M+PS+TP P
Sbjct: 1589 PMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPV 1648
Query: 500 QAPPPLAAPPLQLAKPPPQAPPALATP-PLQALPSPPASFPGQAPFSPSASLPMSPLATP 558
AP P+ AP P P L +P Q L PA P SPS +L L T
Sbjct: 1649 PAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTL---SLGTG 1705
Query: 559 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR- 617
PQ P L + P+ PT A PGP GP TL+LAP PP P+
Sbjct: 1706 NPQGP--FPTQTLSLTPASSLVPT-PAQTLSLAPGPPL---GPTQTLSLAPAPPLAPASP 1759
Query: 618 ---SPSSTLSGPDLAGHSSSAT-STPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS- 672
+P+ TL+ LA SSSA+ P ++ P P LA + S
Sbjct: 1760 VGPAPAHTLT---LAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSP 1816
Query: 673 RGPAPPLAFRGAPGAPLPWPPATG-PGSADGLCTIYETEGPESATPAPGALDPGPSP 728
A L + APLP + P S D T+ GP S P+ GP P
Sbjct: 1817 ASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPS-PPSTATSFGGPRP 1872
Score = 140 bits (352), Expect = 7e-33
Identities = 182/623 (29%), Positives = 241/623 (38%), Gaps = 85/623 (13%)
Query: 13 AARTPAARAPGLLTPRPPGSP-RPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71
A R P++ P +L PRP +P R P P A + V +PL + +
Sbjct: 1330 APRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLV--RPLLKLVHS-PSPEVS 1386
Query: 72 ESAPRAGPTRSAG-----TSSRNPASRP-PASGRGERAPPAKNTSPGPVSSPGRAS-GTT 124
SAP A P + +S PAS P P A P +T P+SS S TT
Sbjct: 1387 ASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTT 1446
Query: 125 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP-SPAMARRSRAA 183
P P AP +SA SGP T +P +A
Sbjct: 1447 LPAP-------------------ASAPLTIPISAPLTVSASGPALLTSVTPPLA------ 1481
Query: 184 GTEVGLPRPAPSARPRPPTEGPRKSVSSASEHS---TTEPSPAARRRPSAGGGLQRPASR 240
P A P PP+ P + SAS + T PS ++ + P L +S
Sbjct: 1482 --------PVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSH 1533
Query: 241 --SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP 298
L+S+ P SP SA +P PS P P QA + + A L P
Sbjct: 1534 VPGLNSTVAPACSPVLVPASALASP----FPSAPNPAPAQASLLAPASSASQALATPLAP 1589
Query: 299 LSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPP 358
+++ A +PS A P L +P ++ + TP+P+ PS + SL + P
Sbjct: 1590 MAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVP 1649
Query: 359 ATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLS 418
A P A +S T + LP+P SPL P P + LAL P AP +SP +
Sbjct: 1650 APTPVLAPSS--------TQTMLPAPVPSPL--PSPASTQTLALAPALAPTLGGSSPSQT 1699
Query: 419 -PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 477
L T +PQ P L S P+P +P PP+ P+ T S AP AP
Sbjct: 1700 LSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAP--GPPLGPTQT-LSLAP----AP 1752
Query: 478 PLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPSPPA 536
PL P SP P P + L AP +Q P P L Q L PA
Sbjct: 1753 PL-APASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPA 1811
Query: 537 SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT 596
S Q+P S ++SL +S P PV L V P + TL++ P P T
Sbjct: 1812 S--TQSPASQASSLVVSASGAAP---LPVTMVSRLPVSKDEPDTLTLRS-GPPSPPSTAT 1865
Query: 597 SVSGPRLTLALAPGPPPPPSRSP 619
S GPR PPPP RSP
Sbjct: 1866 SFGGPR-----PRRQPPPPPRSP 1883
Score = 117 bits (294), Expect = 3e-26
Identities = 195/750 (26%), Positives = 269/750 (35%), Gaps = 161/750 (21%)
Query: 30 PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRN 89
P +P P PV P L A G P + A++ SA AGP
Sbjct: 1015 PRAPLGPVPVRPPPGPELSAQPTPGPVPQ------VLPASLMVSASPAGPPLI------- 1061
Query: 90 PASRPPASGRGERAPPAKNTSPGPVSSP-GRASGTTRPGPLGQKGLRISAEETVARGKAT 148
PASRPP P + P + SP G SGT+RP P L+ + V A
Sbjct: 1062 PASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRP-PTPTLSLKPTPPAPVRLSPAP 1120
Query: 149 EAPKRSALSAGARRDTSGPTPGTPSPAMARRSR---AAGTEVGLPRPAPSARPRPPTEGP 205
S L + + P T PA A + A T +P P P+ + +
Sbjct: 1121 PPGSSSLL-----KPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDM 1175
Query: 206 RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA 265
+ + S S + + A+R P A G +P + + + L+ A+ A G PR
Sbjct: 1176 QARLPSGEVVSIGQLASLAQR-PVANAGGSKPLTFQIQGNKLTLTG-AQVRQLAVGQPR- 1232
Query: 266 PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATP 325
P +++ + L + AL PT TP
Sbjct: 1233 ---------------------PLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTP 1271
Query: 326 HSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTL---QATHSFL- 381
S LP + PS + P+ +LP P + G + QA L
Sbjct: 1272 VSV---------LPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLT 1322
Query: 382 PSPPLSPLATPPPQAPPALALP-PLQAP---PSPPASPPLSPLATPSPQAPNALAVHLLQ 437
P PPL+P PP PA+ P P P P+P +P+ TP+ P VH
Sbjct: 1323 PVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVH--- 1379
Query: 438 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP---PLQVPPSPPASPPMSPS 494
PSP V A S P + P++ S+ P P SL P P+ +P S P + P+S +
Sbjct: 1380 -----SPSPEVSA--SAPGAAPLTISS--PLHVPSSLPGPASSPMPIPNSSPLASPVSST 1430
Query: 495 ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSP 554
+ P + P++ P L A S P + P AP + SAS P
Sbjct: 1431 VSVPLSSSLPISVPTT-----------------LPAPASAPLTIPISAPLTVSASGPALL 1473
Query: 555 LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD-TSVSGPRLTLALAPGPPP 613
+ PP AP V AAP PP+ P S S LTL LA P
Sbjct: 1474 TSVTPPLAPVVPAAP------------------GPPSLAPSGASPSASALTLGLATAP-- 1513
Query: 614 PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR 673
+LS GH T + G +S + P + LA+ P+A +
Sbjct: 1514 --------SLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNP 1565
Query: 674 GP----------------APPLAFRGAPG----APLPWPP-------ATGPGSADGLCTI 706
P A PLA AP AP P PP A PG+A L +
Sbjct: 1566 APAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLAS- 1624
Query: 707 YETEGPESATPAPGALDPGPSPGTSGGKAA 736
S TP P + P +PGTS A+
Sbjct: 1625 -------SQTPVP-VMAPSSTPGTSLASAS 1646
Score = 100 bits (250), Expect = 4e-21
Identities = 168/655 (25%), Positives = 236/655 (36%), Gaps = 103/655 (15%)
Query: 218 TEPSPAARRRP--SAGGGLQRPASRSLSSSATPLSSP-ARSGPSARGTPRAPAHPSQPKP 274
T P P R +P + +P + + +++P A GP P P +QP P
Sbjct: 979 TAPDPPPRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSAQPTP 1038
Query: 275 KGLQALRP---------------PQVTPPRKDAAPALGPLSSS-PLATPSPSAALQSQAP 318
+ + P P PP P L P S S P PSP L +
Sbjct: 1039 GPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSR 1098
Query: 319 PTLPATPHSSSLTCQLATPLPLAP-PSPSAPPSLQTLPSPPA-TPPSQATTSLGSPTLQA 376
P P SL P+ L+P P P + L+ L PP T P A T+ + T A
Sbjct: 1099 PPTPTL----SLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATA 1154
Query: 377 THSFLPSPPLSP---LATPPPQAP------------PALALPPL-QAPPSPPAS------ 414
T + +P+P +P + +P QA +LA P+ A S P +
Sbjct: 1155 TTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGN 1214
Query: 415 ------PPLSPLATPSPQAPNALAVHLLQAP------FSPPPSPPVQAPFSPPASPPVS- 461
+ LA P+ VHL+ A P +QA P PVS
Sbjct: 1215 KLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSV 1274
Query: 462 -PSATPPSQAPPSLAAPPLQVPPSPPA-------------SPPMSPSATPPPQAP---PP 504
PS+TP + P+ + PL PP P PP AP PP
Sbjct: 1275 LPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPP 1334
Query: 505 LAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 564
+ P L P P L TP L +P + P P ++ P A P
Sbjct: 1335 SSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAP 1394
Query: 565 VLAAPLLQVPPS--PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP---PPPSRSP 619
+ + L VP S PAS + P P P +S L+ +L P P P+ +P
Sbjct: 1395 LTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAP 1454
Query: 620 SST-LSGPDLAGHSSSA--TSTPEELRGYDSGPEGGAAASPPPDAELAACHPAA---WSR 673
+ +S P S A TS L P AA PP A A A+
Sbjct: 1455 LTIPISAPLTVSASGPALLTSVTPPL-----APVVPAAPGPPSLAPSGASPSASALTLGL 1509
Query: 674 GPAPPLAFRGAPGAPLPWPPATG--PG---SADGLCTIYETEGPESATPAPGALDPGPSP 728
AP L+ PG PL P + PG + C+ A+P P A +P P+
Sbjct: 1510 ATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQ 1569
Query: 729 GTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAA 783
+ A++ + A A+ +P A P A+ A L+ +LA + GAA
Sbjct: 1570 ASLLAPASSASQALATPLAPMAA-----PQTAILAPSPAPPLAPLPVLAPSPGAA 1619
Score = 91.7 bits (226), Expect = 3e-18
Identities = 178/676 (26%), Positives = 241/676 (35%), Gaps = 102/676 (15%)
Query: 102 RAPPAKNTSPGP--VSSPGRASGTTRPGPLGQK----GLRISAEETVARGKATEAPKRSA 155
R P + PG SS G GT R + G R+S AR + A
Sbjct: 2355 RLPQEEEEGPGAGDESSCGTGGGTHRRSKKAKAPERPGTRVSERLRGARAETQGANHTPV 2414
Query: 156 LSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEH 215
+SA R T+ TP SPA R +PRPAP RPRP ++ +
Sbjct: 2415 ISAHQTRSTT--TPPRCSPARER----------VPRPAP--RPRPTPASAPAAIPALVPV 2460
Query: 216 STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPK 275
+ P P + P + S S P SSPA + P A P PAH P
Sbjct: 2461 PVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSSPACTPPPACTPP--PAHTPPPAQT 2518
Query: 276 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLA 335
L P + P + P +++ PL P A L +QA + P + +S+
Sbjct: 2519 CLVTPSSPLLLGP--PSVPISASVTNLPLGL-RPEAELCAQALAS-PESLELASVASSET 2574
Query: 336 TPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPS-----PPLSPLA 390
+ L L PP P +++ LP + + +P+L +P+ P S
Sbjct: 2575 SSLSLVPPKDLLPVAVEILP----VSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEG 2630
Query: 391 TPPPQAPPALALP-------PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 443
T P LP L+ PPS + PL P + + L +A +P
Sbjct: 2631 TTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQ-----EPLEADRTSEELTEAK-TPT 2684
Query: 444 PSP--PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 501
SP P + + A+P S SAT S PS A PP + A + T P
Sbjct: 2685 SSPEKPQELVTAEVAAPSTSSSAT-SSPEGPSPARPPRR---RTSADVEIRGQGTGRPGQ 2740
Query: 502 PPPLAAPPLQLAKPPPQAPPALATPPL-----QALPSPPASFPGQAPFSPSASLP----M 552
PP P L K P + + L Q + PG + S S P M
Sbjct: 2741 PP----GPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPGVSETSASPGSPSVRSM 2796
Query: 553 SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR-RPPTPGPDTSVSGPRLTLALAP-- 609
S + PP P AAP + P+PP P + G + +G LA+ P
Sbjct: 2797 SGPESSPPIGGPCEAAPSSSL-PTPPQQPFIARRHIELGVTGGGSPENGDGALLAITPPA 2855
Query: 610 -----GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD--SGPEGGAAASPPPDAE 662
G PP +RSP+ G D A S+ T G D GPE A P + +
Sbjct: 2856 VKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGKT----NGADPVPGPETLIVADPVLEPQ 2911
Query: 663 LAACHPAAWSRGPAP-----PLAF------RGAPGAPLPWP-PATGPGSADGLCTIYETE 710
L P GP P PL RG P P P T + DG +E
Sbjct: 2912 LI---PGPQPLGPQPVHRPNPLLSPVEKRRRGRPPKARDLPIPGTISSAGDG-----NSE 2963
Query: 711 GPESATPAPGALDPGP 726
P P L P P
Sbjct: 2964 SRTQPPPHPSPLTPLP 2979
Score = 90.1 bits (222), Expect = 8e-18
Identities = 123/439 (28%), Positives = 159/439 (36%), Gaps = 78/439 (17%)
Query: 355 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAP---PSP 411
P P T S+ + T A H+ + S + T PP+ PA P AP P+P
Sbjct: 2388 PERPGTRVSERLRGARAETQGANHTPVISAHQTRSTTTPPRCSPARERVPRPAPRPRPTP 2447
Query: 412 PASPPLSPLATPSP-------QAPNA---LAVHLLQAPFSPPPS--PPVQAPFSPPASPP 459
++P P P P APN L VH+L +P PPPS PP SP +PP
Sbjct: 2448 ASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSP--PPPSQIPPCS---SPACTPP 2502
Query: 460 VSPSATPPSQAPPSLAAPPLQVPPSP----PASPPMSPSATPPPQAPPP--------LAA 507
P+ TPP P A L P SP P S P+S S T P P LA+
Sbjct: 2503 --PACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCAQALAS 2560
Query: 508 P-PLQLAKPPPQAPPALA-TPPLQALPSPPASFP------GQAPFSPSASLPMSPLATPP 559
P L+LA +L+ PP LP P P +PS +L +
Sbjct: 2561 PESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQ 2620
Query: 560 PQAPPVLA-------------APL-------LQVPPSPPASPTLQAPRRPPTPGPD---- 595
Q P A PL L++PPS + LQ P +
Sbjct: 2621 EQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEA 2680
Query: 596 -TSVSGPRLTLALAPGPPPPPSRSPSSTLS--GPDLAGHSSSATSTPEELRGYDSG---- 648
T S P L PS S S+T S GP A TS E+RG +G
Sbjct: 2681 KTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVEIRGQGTGRPGQ 2740
Query: 649 PEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYE 708
P G P + R RGA +P T ++ G ++
Sbjct: 2741 PPGPKVLRKLPGRLVTVVEEKELVRRRRQQ---RGAASTLVPGVSET--SASPGSPSVRS 2795
Query: 709 TEGPESATPAPGALDPGPS 727
GPES+ P G + PS
Sbjct: 2796 MSGPESSPPIGGPCEAAPS 2814
Score = 86.3 bits (212), Expect = 1e-16
Identities = 156/584 (26%), Positives = 206/584 (35%), Gaps = 97/584 (16%)
Query: 12 AAARTPAARAPGLLTP-RPPGSPRPPPPVTPAALRVLGAAGAVGRKPLA-ERAGGIGGAT 69
+A T +A P LLT PP +P P P +L GA+ + L A + +
Sbjct: 1460 SAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQ 1519
Query: 70 IPESAPRAGPTRS---AGTSSRNPASRP---PASGRGERAPPAKNTSPG------PVSSP 117
P PT S S+ PA P PAS P A N +P P SS
Sbjct: 1520 TPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSA 1579
Query: 118 GRASGTT-RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGP------TPG 170
+A T P Q + + AP A A T P TPG
Sbjct: 1580 SQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPG 1639
Query: 171 T------PSPAMARRSRAAGTEVGLPRPAPSARPRP---------PTEGPRKSVSSASEH 215
T P PA + T+ LP P PS P P P P SS S+
Sbjct: 1640 TSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQT 1699
Query: 216 ------STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP 269
+ P P + L +++LS + P P ++ A P APA P
Sbjct: 1700 LSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASP 1759
Query: 270 SQPKPKGLQALRPPQVTPPRKDAAPALGP-------LSSSPLATPSPSAALQSQAPPTLP 322
P P L P +A L P LS +P+ T P+AA P
Sbjct: 1760 VGPAPAHTLTLAPAS------SSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPAST 1813
Query: 323 ATPHSSS----LTCQLATPLPLA-----PPSPSAPPSLQTLPSPPATPPSQATTSLGSPT 373
+P S + ++ A PLP+ P S P +L TL S P +PPS AT+ G
Sbjct: 1814 QSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTL-TLRSGPPSPPSTATSFGG--- 1869
Query: 374 LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALA- 432
P P P PPP++P L L+ S L + S +A ALA
Sbjct: 1870 --------PRPRRQP--PPPPRSP--FYLDSLEEKRKRQRSERLERIFQLS-EAHGALAP 1916
Query: 433 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ------------ 480
V+ + PV +P P + P P+ ++A P Q
Sbjct: 1917 VYGTEVLDFCTLPQPVASPIGPRSPGPSHPTFWTYTEAAHRAVLFPQQRLDQLSEIIERF 1976
Query: 481 --VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP-PQAPP 521
V P A PP + PPP P AA QLA P+A P
Sbjct: 1977 IFVMPPVEAPPPSLHACHPPPWLAPRQAAFQEQLASELWPRARP 2020
Score = 83.2 bits (204), Expect = 9e-16
Identities = 197/811 (24%), Positives = 266/811 (32%), Gaps = 172/811 (21%)
Query: 27 PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPL-AERAGGIGGATIPESAPRAG--PTRSA 83
PRP PRP P PAA+ L P+ A I I S P P S+
Sbjct: 2437 PRPAPRPRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSS 2496
Query: 84 GTSSRNPASRPPASGRGERAPPAKN-----TSP---GPVSSPGRASGTTRPGPLGQKGLR 135
+ PA PP + PPA+ +SP GP S P AS T P GLR
Sbjct: 2497 PACTPPPACTPPPA---HTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLP-----LGLR 2548
Query: 136 ISAEETVARGKATEAPKRSALSAGARRDTS-------------------------GPTPG 170
AE +A +P+ L++ A +TS TP
Sbjct: 2549 PEAE---LCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPS 2605
Query: 171 TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA 230
PS + S G E P A EG + + + P AA P
Sbjct: 2606 APSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEP-- 2663
Query: 231 GGGLQRP-----ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ--PKPKGLQALRPP 283
LQ P S L+ + TP SSP + AP+ S P+G RPP
Sbjct: 2664 ---LQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPP 2720
Query: 284 QVTPPRKDAAPA--LGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQ-------L 334
+ R+ +A G + P P P + + P L L +
Sbjct: 2721 R----RRTSADVEIRGQGTGRPGQPPGPK--VLRKLPGRLVTVVEEKELVRRRRQQRGAA 2774
Query: 335 ATPLPLAPPSPSAP--PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP---- 388
+T +P + ++P PS++++ P ++PP +G P A S LP+PP P
Sbjct: 2775 STLVPGVSETSASPGSPSVRSMSGPESSPP------IGGPCEAAPSSSLPTPPQQPFIAR 2828
Query: 389 --------------------LATPPPQAPPALALPPLQAPPSPPA-----SPPLSPL--- 420
LA PP PP + A P S L
Sbjct: 2829 RHIELGVTGGGSPENGDGALLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGK 2888
Query: 421 ---ATPSPQAPNALAV--HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA 475
A P P P L V +L+ P P P P P +P +SP PP
Sbjct: 2889 TNGADPVP-GPETLIVADPVLEPQLIPGPQPLGPQPVHRP-NPLLSPVEKRRRGRPPK-- 2944
Query: 476 APPLQVPPS-PPASPPMSPSATPPPQAPPPLA-APPLQLAKPPPQAPPALATPPLQALPS 533
A L +P + A S S T PP P PL PPL + P A A + S
Sbjct: 2945 ARDLPIPGTISSAGDGNSESRTQPPPHPSPLTPLPPLLVC---PTATVANTVTTVTISTS 3001
Query: 534 PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG 593
PP G+ P +P +P P PVL V S Q + + G
Sbjct: 3002 PPKRKRGRPPKNP---------PSPRPSQLPVLDRDSTSVLESCGLGRRRQPQGQGESEG 3052
Query: 594 PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATST----PEELRGYDSGP 649
+ G R P +R L + G S + ++L DSGP
Sbjct: 3053 SSSDEDGSR-----------PLTRLARLRLEAEGMRGRKSGGSMVVAVIQDDLDLADSGP 3101
Query: 650 EG--------------------GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPL 689
G + PP + E A G +P LA RG P
Sbjct: 3102 GGLELTPPVVSLTPKLRSTRLRPGSLVPPLETEKLPRKRAGAPVGGSPGLAKRGRLQPPS 3161
Query: 690 PWPPATGPGSADGLCTIYETEGPESATPAPG 720
P P ++ + E EG + PG
Sbjct: 3162 PLGPEGSVEESEAEASGEEEEGDGTPRRRPG 3192
Score = 74.7 bits (182), Expect = 3e-13
Identities = 108/456 (23%), Positives = 152/456 (33%), Gaps = 65/456 (14%)
Query: 379 SFLPSPPLS-------PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNAL 431
+FLP LS A PP P + + + P + + +P+AP
Sbjct: 962 TFLPRHRLSRRVLLEVATAPDPPPRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAP--- 1018
Query: 432 AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 491
L P PPP P + A +P P V P++ S +P P PP P PP+
Sbjct: 1019 ---LGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPL 1075
Query: 492 SPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 551
P++ PQ P ++PP TP L P+PPA P +S
Sbjct: 1076 QPNSGSLPQVLPSPLGVLSGTSRPP--------TPTLSLKPTPPAPVRLSPAPPPGSSSL 1127
Query: 552 MSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 611
+ PL PP P AA + + + A PTP P + P + L G
Sbjct: 1128 LKPLTVPPGYTFPPAAATTTSTTTATATTTAVPA----PTPAPQRLILSPDMQARLPSGE 1183
Query: 612 PPPPSRSPSSTLSGPDLAGHS---------SSATSTPEELRGYDSG-------------P 649
+ S AG S + T T ++R G
Sbjct: 1184 VVSIGQLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVS 1243
Query: 650 EGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG-PGSAD------- 701
GG A +A A + GP P + + P P P +A+
Sbjct: 1244 AGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMV 1303
Query: 702 ---GLCTIYETEGP-ESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELP 757
G+ I + P + TP P L P P P +SG A + RL
Sbjct: 1304 NNTGVVKIVVRQAPRDGLTPVP-PLAPAPRPPSSGLPAVLNPRPTLT-----PGRLPTPT 1357
Query: 758 LGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGA 793
LG +A + L R LL + S PG A
Sbjct: 1358 LGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAA 1393
Score = 39.7 bits (91), Expect = 0.012
Identities = 83/365 (22%), Positives = 117/365 (32%), Gaps = 46/365 (12%)
Query: 8 AKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG 67
A A A A T +P G+P+ P P +L + + L+ G G
Sbjct: 1682 ALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLG 1741
Query: 68 ATIPES---APRAGPTRSAGTSSRNPASRPPASGRGERAPPAK----NTSPGPVSSPGRA 120
T S AP P G + + + PAS PA SP PV + G A
Sbjct: 1742 PTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLGPA 1801
Query: 121 SGTT---RPGPLGQKGLRISAEETVARGKA---TEAPKRSALSAGARRDTSGPTPGTPSP 174
+ T P + S+ A G A R +S DT G PSP
Sbjct: 1802 AAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKD-EPDTLTLRSGPPSP 1860
Query: 175 AMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL 234
+ T G PRP P P + S+ + +E + A G L
Sbjct: 1861 P------STATSFGGPRPRRQPPPPPRSPFYLDSLEEKRKRQRSERLERIFQLSEAHGAL 1914
Query: 235 QRPASRSLSSSAT---PLSSPARSGPSARGTPRAPAHPS---QPKPKGLQALRPPQ---- 284
+ T P++SP GP + G P+HP+ + L P Q
Sbjct: 1915 APVYGTEVLDFCTLPQPVASPI--GPRSPG----PSHPTFWTYTEAAHRAVLFPQQRLDQ 1968
Query: 285 ----------VTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQL 334
V PP + P+L P P +A + A P + C +
Sbjct: 1969 LSEIIERFIFVMPPVEAPPPSLHACHPPPWLAPRQAAFQEQLASELWPRARPLHRIVCNM 2028
Query: 335 ATPLP 339
T P
Sbjct: 2029 RTQFP 2033
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 152 bits (383), Expect = 2e-36
Identities = 189/771 (24%), Positives = 269/771 (34%), Gaps = 102/771 (13%)
Query: 2 DNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAER 61
DNK+++ K + P G P T +V + KP+ R
Sbjct: 68 DNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR 127
Query: 62 AG-GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA 120
T E++ + T ++ ++ E+ AK T +S
Sbjct: 128 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 187
Query: 121 SGTTR----PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM 176
+ T++ P P ET +G A PK + ++ + TP P+P
Sbjct: 188 APTSKVLAKPTPKA---------ETTTKGPALTTPKEPTPTTP--KEPASTTPKEPTPTT 236
Query: 177 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR 236
+ + E PAP+ PT P++ + +T EP+P + P A +
Sbjct: 237 IKSAPTTPKE-----PAPTTTKSAPTT-PKEPAPT----TTKEPAPTTPKEP-APTTTKE 285
Query: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296
PA + S+ T PA + P + P P P+ PK P + P K+ AP
Sbjct: 286 PAPTTTKSAPTTPKEPAPTTPK-KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT 344
Query: 297 GPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPS 356
P +P A P+ + PT P P P PSP+ P P+
Sbjct: 345 -PKEPAPTAPKKPAPTTPKEPAPTTPKEP----------APTTTKEPSPTTPKE----PA 389
Query: 357 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT--PPPQAP--PALALPPLQAPPSPP 412
P T + TT +PT + P P SP T P P P PA P AP +P
Sbjct: 390 PTTTKSAPTTTKEPAPTTTKSAPTTPKEP-SPTTTKEPAPTTPKEPAPTTPKKPAPTTPK 448
Query: 413 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ-APFSPPASPPVSPSATPPSQAP 471
P TP AP P P P+ P + AP +P P +P P+
Sbjct: 449 EPAP----TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE 504
Query: 472 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP--PALATPPLQ 529
P ++ P+ P P +P+ P P AA P +P P P PA TP
Sbjct: 505 KPAPTTPEELAPTTPEEP--TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 562
Query: 530 ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP------PASPTL 583
A +P + P + +L TP AP LA + P S P +P
Sbjct: 563 APTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG 622
Query: 584 QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 643
AP P P P T P P P +P+ TL P ++ P+EL
Sbjct: 623 TAPTTPKEPAPTTPKE---------PAPTTPKGTAPT-TLKEP---APTTPKKPAPKELA 669
Query: 644 GYDS-GPEGGAAASPPPDA--ELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSA 700
+ GP + P P E A P + PAP P P P P T P +
Sbjct: 670 PTTTKGPTSTTSDKPAPTTPKETAPTTP----KEPAPT-----TPKKPAPTTPETPPPTT 720
Query: 701 DGLCTIYETEGPE-------------SATPAPGALDPGP-SPGTSGGKAAA 737
+ T T+ P SA P P AL+ P PG K A
Sbjct: 721 SEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPA 771
Score = 150 bits (378), Expect = 6e-36
Identities = 171/673 (25%), Positives = 240/673 (35%), Gaps = 84/673 (12%)
Query: 71 PESAPRAGPTRSAGTSSRNPASRPPASGRGERAP-PAKNTSPGPVSSPGRASGTT--RPG 127
P S A PT A T+++ PA P PA T P + +++ TT P
Sbjct: 189 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 248
Query: 128 PLGQKGLRISAEE---TVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184
P K + +E T + A PK A + T P P T A A
Sbjct: 249 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT-----TKEPAPTTTKSAPTTPKEPAP 303
Query: 185 TEVGLPRPAPSARPRPPT-EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 243
T P P P P T + P + +T EP+P + P+
Sbjct: 304 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP------------- 350
Query: 244 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 303
++P + P+ TP+ PA P+ PK + P T P++ PA S+P
Sbjct: 351 ------TAPKKPAPT---TPKEPA-PTTPKEPAPTTTKEPSPTTPKE---PAPTTTKSAP 397
Query: 304 LATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPS 363
T P A +++ PT P P ++ P P P P+ P+ P+P TP
Sbjct: 398 TTTKEP-APTTTKSAPTTPKEPSPTTTK----EPAPTTPKEPA--PTTPKKPAP-TTPKE 449
Query: 364 QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATP 423
A T+ P T P+ P P T P + P P P +P P +P P
Sbjct: 450 PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT--PKKLTPTTPEKLAPTTP-EKP 506
Query: 424 SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA-TPPSQAPPSLAAPPLQVP 482
+P P LA + P P +P AP +P A+ P +P P + P+ P P
Sbjct: 507 APTTPEELAPTTPEEP--TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 564
Query: 483 PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP-GQ 541
+P + P +P T P P P + A P AP P P + P G
Sbjct: 565 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKEPTSTTCDKPAPTTPKGT 623
Query: 542 APFSPSASLPMSPLATPPPQAPPVLAAPLLQVP-PSPPASPTLQAPRRPPTPGPDTSVSG 600
AP +P P +P P P P A L+ P P+ P P + T GP ++ S
Sbjct: 624 APTTPKEPAPTTP-KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 682
Query: 601 ------PRLTLALAP---GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 651
P+ T P P P +P++ + P S+ T+T E + S E
Sbjct: 683 KPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDES 742
Query: 652 GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETE- 710
S P P A P PG P PA TE
Sbjct: 743 TPELSAEPT-------PKALENSPK-------EPGVPTTKTPAATKPEMTTTAKDKTTER 788
Query: 711 ----GPESATPAP 719
PE+ T AP
Sbjct: 789 DLRTTPETTTAAP 801
Score = 150 bits (378), Expect = 6e-36
Identities = 166/658 (25%), Positives = 231/658 (35%), Gaps = 83/658 (12%)
Query: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63
K + G A TP P TP+ P S P P TP ++ +A ++P
Sbjct: 200 KAETTTKGPALTTPKEPTP--TTPKEPASTTPKEP-TPTTIK---SAPTTPKEP------ 247
Query: 64 GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGT 123
T +SAP P A T+++ PA P PA T+ P + +++ T
Sbjct: 248 ---APTTTKSAPTT-PKEPAPTTTKEPAPTTPKE-------PAPTTTKEPAPTTTKSAPT 296
Query: 124 TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA 183
T P T + A PK A + PTP TP A
Sbjct: 297 TPKEPA----------PTTPKKPAPTTPKEPAPTTPKE-----PTPTTPKEPAPTTKEPA 341
Query: 184 GTEVGLPRPAPSARPRP--PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 241
T P P +P P P E + + +T EPSP + P+ P +
Sbjct: 342 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK 401
Query: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301
+ T S+P + T + PA + +P +P TP K+ AP P
Sbjct: 402 EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP--KEPAPTT-PKEP 458
Query: 302 SPLATPSPSAALQSQAPPTLPA-TPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPAT 360
+P T P+ + PT P T ++ TP LAP +P P P T
Sbjct: 459 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA--------PTT 510
Query: 361 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL 420
P A T+ PT P+P A P PA P AP +P P +P
Sbjct: 511 PEELAPTTPEEPTPTTPEE--PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK 568
Query: 421 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP-PVSPSATPPSQAPPSLAAP-- 477
T +P P A L+ P P P +P + P S + P+ P AP
Sbjct: 569 ET-APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 627
Query: 478 PLQVPPSPPASP-PMSPSATPP-----PQAPPPLAAPPLQLAKPPPQAPPALA------T 525
P + P+ P P P +P T P P P P +LA + P + T
Sbjct: 628 PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 687
Query: 526 PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 585
P + P+ P AP +P P +P TPPP V + P + SP
Sbjct: 688 TPKETAPTTPKE---PAPTTPKKPAPTTP-ETPPPTTSEVSTPTTTKEPTTIHKSPDEST 743
Query: 586 PRRPPTPGPDTSVSGPRLTLALAPGPP---PPPSRSPSSTLSGPDLAGHSSSATSTPE 640
P P P + P+ PG P P + P T + D T TPE
Sbjct: 744 PELSAEPTPKALENSPK-----EPGVPTTKTPAATKPEMTTTAKDKTTERDLRT-TPE 795
Score = 130 bits (327), Expect = 5e-30
Identities = 160/660 (24%), Positives = 233/660 (35%), Gaps = 86/660 (13%)
Query: 144 RGKATEAPKRSALS-AGARRDTSGPTPGTPSPAMARRSRAAGT-EVGLPRPAPSARPRPP 201
R K PK + AG+ D TP + + ++ + + ++ +P PP
Sbjct: 73 RTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPP 132
Query: 202 TEGPRKSVSSASEHSTT---EPSPAARRRPSAGG-----------GLQRPASRSLSSSAT 247
K S TT + + ++ S G +++ +++ L+ ++
Sbjct: 133 NSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 192
Query: 248 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 307
L+ P P A T + PA + +P P TP K+ P + S+P TP
Sbjct: 193 VLAKPT---PKAETTTKGPALTTPKEPTPTTPKEPASTTP--KEPTPTT--IKSAP-TTP 244
Query: 308 SPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATT 367
A +++ PT P P P P+P+ P P+P T TT
Sbjct: 245 KEPAPTTTKSAPTTPKEP----------APTTTKEPAPTTPKE----PAPTTTKEPAPTT 290
Query: 368 SLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLAT----P 423
+ +PT + P+ P P T P + P P P PA P T P
Sbjct: 291 TKSAPTTPKEPA--PTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 348
Query: 424 SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA-SPPVSPSATPPSQAPPSLAAPPLQVP 482
+P AP A + P P P P+ + P P+ T AP + P
Sbjct: 349 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 408
Query: 483 PSPPASP-PMSPSATPPPQAPPPLAAPPLQLAKPPPQAP--PALATP----------PLQ 529
S P +P SP+ T P P P KP P P PA TP P
Sbjct: 409 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP 468
Query: 530 ALPSPPASFPGQ--APFSPSASLPMSP--LATPPPQAP----PVLAAPLLQVPPSP---- 577
P PA + AP +P P +P LA P+ P P AP P+P
Sbjct: 469 TTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE 528
Query: 578 ---PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 634
P +P AP P P P T+ P T P P P +P +T G
Sbjct: 529 EPAPTTPKAAAPNTPKEPAP-TTPKEPAPTTPKEPAPTTPKETAP-TTPKGTAPTTLKEP 586
Query: 635 ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS-RGPAPPLAFRGAPGAPLPWPP 693
A +TP++ P+ A + PA + +G AP AP P P
Sbjct: 587 APTTPKK-----PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP 641
Query: 694 ATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG---TSGGKAAAGAGAGASSRSPKQ 750
T G+A T+ E PAP L P + G T+ K A + +PK+
Sbjct: 642 TTPKGTAP--TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE 699
Score = 101 bits (251), Expect = 3e-21
Identities = 155/660 (23%), Positives = 222/660 (33%), Gaps = 113/660 (17%)
Query: 13 AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPE 72
A TP AP P +P+ P P TP K A T E
Sbjct: 302 APTTPKKPAPTTPKEPAPTTPKEPTPTTP--------------KEPAPTTKEPAPTTPKE 347
Query: 73 SAPRAGPTRSAGTSSRNPAS---RPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129
AP A P + A T+ + PA + PA + P P P ++ + T P P
Sbjct: 348 PAPTA-PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 406
Query: 130 GQKGLRISAEE---TVARGKATEAPKRSALSAGARRDTSGPTPGTPS-PAMARRSRAAGT 185
K + +E T + A PK A + + P P TP PA A T
Sbjct: 407 TTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK-----PAPTTPKEPAPTTPKEPAPT 461
Query: 186 EVGLPRPAPSARPRP-----------------------PTEGPRKSVSSASEHSTT---E 219
P P P P PT + + ++ E + T E
Sbjct: 462 TTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE 521
Query: 220 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS--ARGTPRAPAHPSQPK---- 273
P+P P+ P + ++ TP PA + P A TP+ PA P+ PK
Sbjct: 522 PTPTTPEEPA-------PTTPKAAAPNTP-KEPAPTTPKEPAPTTPKEPA-PTTPKETAP 572
Query: 274 --PKGLQ--ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSS 329
PKG L+ P T P+K A L P ++ + + + T P TP +
Sbjct: 573 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 632
Query: 330 LTCQLATPLPLAPPSP--SAPPSLQ----TLPSPPATPPSQATTSLGSPTLQATHSFLPS 383
T TP AP +P +AP +L+ T P PA P A T+ PT + P+
Sbjct: 633 PT----TPKEPAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSDKPAPT 687
Query: 384 PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 443
P T P + PA P AP +P PP + + +H +P
Sbjct: 688 TPKETAPTTPKE--PAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 745
Query: 444 PS--PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV--------PPSPPASPPMSP 493
S P +A + P P V + TP + P + P + A+P M+
Sbjct: 746 LSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTK 805
Query: 494 --SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS------ 545
+ T + A Q+ Q L+ P + +
Sbjct: 806 ETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMN 865
Query: 546 -------PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS-PTLQAPRRPPTPGPDTS 597
P S TP PQ P AP P + P ++ P+ PTP TS
Sbjct: 866 KPEETAKPKDRATNSKATTPKPQKPT--KAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTS 923
Score = 30.0 bits (66), Expect = 9.5
Identities = 40/195 (20%), Positives = 68/195 (34%), Gaps = 23/195 (11%)
Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT--RSA 83
+P+ PG P P A + L T PE+ A +A
Sbjct: 758 SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLR---------TTPETTTAAPKMTKETA 808
Query: 84 GTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVA 143
T+ + S+ A+ + ++T+P +++ TT + I+ E +
Sbjct: 809 TTTEKTTESKITATTTQVTSTTTQDTTPFKITT---LKTTTLAPKVTTTKKTITTTEIMN 865
Query: 144 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE 203
+ + T PK A ++ A TP P ++ T P+ P R T
Sbjct: 866 KPEETAKPKDRATNSKAT---------TPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTP 916
Query: 204 GPRKSVSSASEHSTT 218
PRK S+ E + T
Sbjct: 917 TPRKMTSTMPELNPT 931
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 152 bits (383), Expect = 2e-36
Identities = 189/771 (24%), Positives = 269/771 (34%), Gaps = 102/771 (13%)
Query: 2 DNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAER 61
DNK+++ K + P G P T +V + KP+ R
Sbjct: 109 DNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR 168
Query: 62 AG-GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA 120
T E++ + T ++ ++ E+ AK T +S
Sbjct: 169 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 228
Query: 121 SGTTR----PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM 176
+ T++ P P ET +G A PK + ++ + TP P+P
Sbjct: 229 APTSKVLAKPTPKA---------ETTTKGPALTTPKEPTPTTP--KEPASTTPKEPTPTT 277
Query: 177 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR 236
+ + E PAP+ PT P++ + +T EP+P + P A +
Sbjct: 278 IKSAPTTPKE-----PAPTTTKSAPTT-PKEPAPT----TTKEPAPTTPKEP-APTTTKE 326
Query: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296
PA + S+ T PA + P + P P P+ PK P + P K+ AP
Sbjct: 327 PAPTTTKSAPTTPKEPAPTTPK-KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT 385
Query: 297 GPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPS 356
P +P A P+ + PT P P P PSP+ P P+
Sbjct: 386 -PKEPAPTAPKKPAPTTPKEPAPTTPKEP----------APTTTKEPSPTTPKE----PA 430
Query: 357 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT--PPPQAP--PALALPPLQAPPSPP 412
P T + TT +PT + P P SP T P P P PA P AP +P
Sbjct: 431 PTTTKSAPTTTKEPAPTTTKSAPTTPKEP-SPTTTKEPAPTTPKEPAPTTPKKPAPTTPK 489
Query: 413 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ-APFSPPASPPVSPSATPPSQAP 471
P TP AP P P P+ P + AP +P P +P P+
Sbjct: 490 EPAP----TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE 545
Query: 472 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP--PALATPPLQ 529
P ++ P+ P P +P+ P P AA P +P P P PA TP
Sbjct: 546 KPAPTTPEELAPTTPEEP--TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 603
Query: 530 ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP------PASPTL 583
A +P + P + +L TP AP LA + P S P +P
Sbjct: 604 APTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG 663
Query: 584 QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 643
AP P P P T P P P +P+ TL P ++ P+EL
Sbjct: 664 TAPTTPKEPAPTTPKE---------PAPTTPKGTAPT-TLKEP---APTTPKKPAPKELA 710
Query: 644 GYDS-GPEGGAAASPPPDA--ELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSA 700
+ GP + P P E A P + PAP P P P P T P +
Sbjct: 711 PTTTKGPTSTTSDKPAPTTPKETAPTTP----KEPAPT-----TPKKPAPTTPETPPPTT 761
Query: 701 DGLCTIYETEGPE-------------SATPAPGALDPGP-SPGTSGGKAAA 737
+ T T+ P SA P P AL+ P PG K A
Sbjct: 762 SEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPA 812
Score = 150 bits (378), Expect = 6e-36
Identities = 171/673 (25%), Positives = 240/673 (35%), Gaps = 84/673 (12%)
Query: 71 PESAPRAGPTRSAGTSSRNPASRPPASGRGERAP-PAKNTSPGPVSSPGRASGTT--RPG 127
P S A PT A T+++ PA P PA T P + +++ TT P
Sbjct: 230 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 289
Query: 128 PLGQKGLRISAEE---TVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184
P K + +E T + A PK A + T P P T A A
Sbjct: 290 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT-----TKEPAPTTTKSAPTTPKEPAP 344
Query: 185 TEVGLPRPAPSARPRPPT-EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 243
T P P P P T + P + +T EP+P + P+
Sbjct: 345 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP------------- 391
Query: 244 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 303
++P + P+ TP+ PA P+ PK + P T P++ PA S+P
Sbjct: 392 ------TAPKKPAPT---TPKEPA-PTTPKEPAPTTTKEPSPTTPKE---PAPTTTKSAP 438
Query: 304 LATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPS 363
T P A +++ PT P P ++ P P P P+ P+ P+P TP
Sbjct: 439 TTTKEP-APTTTKSAPTTPKEPSPTTTK----EPAPTTPKEPA--PTTPKKPAP-TTPKE 490
Query: 364 QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATP 423
A T+ P T P+ P P T P + P P P +P P +P P
Sbjct: 491 PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT--PKKLTPTTPEKLAPTTP-EKP 547
Query: 424 SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA-TPPSQAPPSLAAPPLQVP 482
+P P LA + P P +P AP +P A+ P +P P + P+ P P
Sbjct: 548 APTTPEELAPTTPEEP--TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 605
Query: 483 PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP-GQ 541
+P + P +P T P P P + A P AP P P + P G
Sbjct: 606 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKEPTSTTCDKPAPTTPKGT 664
Query: 542 APFSPSASLPMSPLATPPPQAPPVLAAPLLQVP-PSPPASPTLQAPRRPPTPGPDTSVSG 600
AP +P P +P P P P A L+ P P+ P P + T GP ++ S
Sbjct: 665 APTTPKEPAPTTP-KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 723
Query: 601 ------PRLTLALAP---GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 651
P+ T P P P +P++ + P S+ T+T E + S E
Sbjct: 724 KPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDES 783
Query: 652 GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETE- 710
S P P A P PG P PA TE
Sbjct: 784 TPELSAEPT-------PKALENSPK-------EPGVPTTKTPAATKPEMTTTAKDKTTER 829
Query: 711 ----GPESATPAP 719
PE+ T AP
Sbjct: 830 DLRTTPETTTAAP 842
Score = 150 bits (378), Expect = 6e-36
Identities = 166/658 (25%), Positives = 231/658 (35%), Gaps = 83/658 (12%)
Query: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63
K + G A TP P TP+ P S P P TP ++ +A ++P
Sbjct: 241 KAETTTKGPALTTPKEPTP--TTPKEPASTTPKEP-TPTTIK---SAPTTPKEP------ 288
Query: 64 GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGT 123
T +SAP P A T+++ PA P PA T+ P + +++ T
Sbjct: 289 ---APTTTKSAPTT-PKEPAPTTTKEPAPTTPKE-------PAPTTTKEPAPTTTKSAPT 337
Query: 124 TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA 183
T P T + A PK A + PTP TP A
Sbjct: 338 TPKEPA----------PTTPKKPAPTTPKEPAPTTPKE-----PTPTTPKEPAPTTKEPA 382
Query: 184 GTEVGLPRPAPSARPRP--PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 241
T P P +P P P E + + +T EPSP + P+ P +
Sbjct: 383 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK 442
Query: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301
+ T S+P + T + PA + +P +P TP K+ AP P
Sbjct: 443 EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP--KEPAPTT-PKEP 499
Query: 302 SPLATPSPSAALQSQAPPTLPA-TPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPAT 360
+P T P+ + PT P T ++ TP LAP +P P P T
Sbjct: 500 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA--------PTT 551
Query: 361 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL 420
P A T+ PT P+P A P PA P AP +P P +P
Sbjct: 552 PEELAPTTPEEPTPTTPEE--PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK 609
Query: 421 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP-PVSPSATPPSQAPPSLAAP-- 477
T +P P A L+ P P P +P + P S + P+ P AP
Sbjct: 610 ET-APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 668
Query: 478 PLQVPPSPPASP-PMSPSATPP-----PQAPPPLAAPPLQLAKPPPQAPPALA------T 525
P + P+ P P P +P T P P P P +LA + P + T
Sbjct: 669 PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 728
Query: 526 PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 585
P + P+ P AP +P P +P TPPP V + P + SP
Sbjct: 729 TPKETAPTTPKE---PAPTTPKKPAPTTP-ETPPPTTSEVSTPTTTKEPTTIHKSPDEST 784
Query: 586 PRRPPTPGPDTSVSGPRLTLALAPGPP---PPPSRSPSSTLSGPDLAGHSSSATSTPE 640
P P P + P+ PG P P + P T + D T TPE
Sbjct: 785 PELSAEPTPKALENSPK-----EPGVPTTKTPAATKPEMTTTAKDKTTERDLRT-TPE 836
Score = 130 bits (327), Expect = 5e-30
Identities = 160/660 (24%), Positives = 233/660 (35%), Gaps = 86/660 (13%)
Query: 144 RGKATEAPKRSALS-AGARRDTSGPTPGTPSPAMARRSRAAGT-EVGLPRPAPSARPRPP 201
R K PK + AG+ D TP + + ++ + + ++ +P PP
Sbjct: 114 RTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPP 173
Query: 202 TEGPRKSVSSASEHSTT---EPSPAARRRPSAGG-----------GLQRPASRSLSSSAT 247
K S TT + + ++ S G +++ +++ L+ ++
Sbjct: 174 NSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSK 233
Query: 248 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATP 307
L+ P P A T + PA + +P P TP K+ P + S+P TP
Sbjct: 234 VLAKPT---PKAETTTKGPALTTPKEPTPTTPKEPASTTP--KEPTPTT--IKSAP-TTP 285
Query: 308 SPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATT 367
A +++ PT P P P P+P+ P P+P T TT
Sbjct: 286 KEPAPTTTKSAPTTPKEP----------APTTTKEPAPTTPKE----PAPTTTKEPAPTT 331
Query: 368 SLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLAT----P 423
+ +PT + P+ P P T P + P P P PA P T P
Sbjct: 332 TKSAPTTPKEPA--PTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 389
Query: 424 SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA-SPPVSPSATPPSQAPPSLAAPPLQVP 482
+P AP A + P P P P+ + P P+ T AP + P
Sbjct: 390 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 449
Query: 483 PSPPASP-PMSPSATPPPQAPPPLAAPPLQLAKPPPQAP--PALATP----------PLQ 529
S P +P SP+ T P P P KP P P PA TP P
Sbjct: 450 KSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP 509
Query: 530 ALPSPPASFPGQ--APFSPSASLPMSP--LATPPPQAP----PVLAAPLLQVPPSP---- 577
P PA + AP +P P +P LA P+ P P AP P+P
Sbjct: 510 TTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE 569
Query: 578 ---PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 634
P +P AP P P P T+ P T P P P +P +T G
Sbjct: 570 EPAPTTPKAAAPNTPKEPAP-TTPKEPAPTTPKEPAPTTPKETAP-TTPKGTAPTTLKEP 627
Query: 635 ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS-RGPAPPLAFRGAPGAPLPWPP 693
A +TP++ P+ A + PA + +G AP AP P P
Sbjct: 628 APTTPKK-----PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAP 682
Query: 694 ATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG---TSGGKAAAGAGAGASSRSPKQ 750
T G+A T+ E PAP L P + G T+ K A + +PK+
Sbjct: 683 TTPKGTAP--TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE 740
Score = 101 bits (251), Expect = 3e-21
Identities = 155/660 (23%), Positives = 222/660 (33%), Gaps = 113/660 (17%)
Query: 13 AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPE 72
A TP AP P +P+ P P TP K A T E
Sbjct: 343 APTTPKKPAPTTPKEPAPTTPKEPTPTTP--------------KEPAPTTKEPAPTTPKE 388
Query: 73 SAPRAGPTRSAGTSSRNPAS---RPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129
AP A P + A T+ + PA + PA + P P P ++ + T P P
Sbjct: 389 PAPTA-PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 447
Query: 130 GQKGLRISAEE---TVARGKATEAPKRSALSAGARRDTSGPTPGTPS-PAMARRSRAAGT 185
K + +E T + A PK A + + P P TP PA A T
Sbjct: 448 TTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK-----PAPTTPKEPAPTTPKEPAPT 502
Query: 186 EVGLPRPAPSARPRP-----------------------PTEGPRKSVSSASEHSTT---E 219
P P P P PT + + ++ E + T E
Sbjct: 503 TTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE 562
Query: 220 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS--ARGTPRAPAHPSQPK---- 273
P+P P+ P + ++ TP PA + P A TP+ PA P+ PK
Sbjct: 563 PTPTTPEEPA-------PTTPKAAAPNTP-KEPAPTTPKEPAPTTPKEPA-PTTPKETAP 613
Query: 274 --PKGLQ--ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSS 329
PKG L+ P T P+K A L P ++ + + + T P TP +
Sbjct: 614 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 673
Query: 330 LTCQLATPLPLAPPSP--SAPPSLQ----TLPSPPATPPSQATTSLGSPTLQATHSFLPS 383
T TP AP +P +AP +L+ T P PA P A T+ PT + P+
Sbjct: 674 PT----TPKEPAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSDKPAPT 728
Query: 384 PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 443
P T P + PA P AP +P PP + + +H +P
Sbjct: 729 TPKETAPTTPKE--PAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 786
Query: 444 PS--PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV--------PPSPPASPPMSP 493
S P +A + P P V + TP + P + P + A+P M+
Sbjct: 787 LSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTK 846
Query: 494 --SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS------ 545
+ T + A Q+ Q L+ P + +
Sbjct: 847 ETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMN 906
Query: 546 -------PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS-PTLQAPRRPPTPGPDTS 597
P S TP PQ P AP P + P ++ P+ PTP TS
Sbjct: 907 KPEETAKPKDRATNSKATTPKPQKPT--KAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTS 964
Score = 30.0 bits (66), Expect = 9.5
Identities = 40/195 (20%), Positives = 68/195 (34%), Gaps = 23/195 (11%)
Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT--RSA 83
+P+ PG P P A + L T PE+ A +A
Sbjct: 799 SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLR---------TTPETTTAAPKMTKETA 849
Query: 84 GTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVA 143
T+ + S+ A+ + ++T+P +++ TT + I+ E +
Sbjct: 850 TTTEKTTESKITATTTQVTSTTTQDTTPFKITT---LKTTTLAPKVTTTKKTITTTEIMN 906
Query: 144 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE 203
+ + T PK A ++ A TP P ++ T P+ P R T
Sbjct: 907 KPEETAKPKDRATNSKAT---------TPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTP 957
Query: 204 GPRKSVSSASEHSTT 218
PRK S+ E + T
Sbjct: 958 TPRKMTSTMPELNPT 972
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 152 bits (383), Expect = 2e-36
Identities = 189/771 (24%), Positives = 269/771 (34%), Gaps = 102/771 (13%)
Query: 2 DNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAER 61
DNK+++ K + P G P T +V + KP+ R
Sbjct: 161 DNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR 220
Query: 62 AG-GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA 120
T E++ + T ++ ++ E+ AK T +S
Sbjct: 221 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 280
Query: 121 SGTTR----PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM 176
+ T++ P P ET +G A PK + ++ + TP P+P
Sbjct: 281 APTSKVLAKPTPKA---------ETTTKGPALTTPKEPTPTTP--KEPASTTPKEPTPTT 329
Query: 177 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR 236
+ + E PAP+ PT P++ + +T EP+P + P A +
Sbjct: 330 IKSAPTTPKE-----PAPTTTKSAPTT-PKEPAPT----TTKEPAPTTPKEP-APTTTKE 378
Query: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296
PA + S+ T PA + P + P P P+ PK P + P K+ AP
Sbjct: 379 PAPTTTKSAPTTPKEPAPTTPK-KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT 437
Query: 297 GPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPS 356
P +P A P+ + PT P P P PSP+ P P+
Sbjct: 438 -PKEPAPTAPKKPAPTTPKEPAPTTPKEP----------APTTTKEPSPTTPKE----PA 482
Query: 357 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT--PPPQAP--PALALPPLQAPPSPP 412
P T + TT +PT + P P SP T P P P PA P AP +P
Sbjct: 483 PTTTKSAPTTTKEPAPTTTKSAPTTPKEP-SPTTTKEPAPTTPKEPAPTTPKKPAPTTPK 541
Query: 413 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ-APFSPPASPPVSPSATPPSQAP 471
P TP AP P P P+ P + AP +P P +P P+
Sbjct: 542 EPAP----TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE 597
Query: 472 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP--PALATPPLQ 529
P ++ P+ P P +P+ P P AA P +P P P PA TP
Sbjct: 598 KPAPTTPEELAPTTPEEP--TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 655
Query: 530 ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP------PASPTL 583
A +P + P + +L TP AP LA + P S P +P
Sbjct: 656 APTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG 715
Query: 584 QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 643
AP P P P T P P P +P+ TL P ++ P+EL
Sbjct: 716 TAPTTPKEPAPTTPKE---------PAPTTPKGTAPT-TLKEP---APTTPKKPAPKELA 762
Query: 644 GYDS-GPEGGAAASPPPDA--ELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSA 700
+ GP + P P E A P + PAP P P P P T P +
Sbjct: 763 PTTTKGPTSTTSDKPAPTTPKETAPTTP----KEPAPT-----TPKKPAPTTPETPPPTT 813
Query: 701 DGLCTIYETEGPE-------------SATPAPGALDPGP-SPGTSGGKAAA 737
+ T T+ P SA P P AL+ P PG K A
Sbjct: 814 SEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPA 864
Score = 150 bits (378), Expect = 6e-36
Identities = 171/673 (25%), Positives = 240/673 (35%), Gaps = 84/673 (12%)
Query: 71 PESAPRAGPTRSAGTSSRNPASRPPASGRGERAP-PAKNTSPGPVSSPGRASGTT--RPG 127
P S A PT A T+++ PA P PA T P + +++ TT P
Sbjct: 282 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 341
Query: 128 PLGQKGLRISAEE---TVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184
P K + +E T + A PK A + T P P T A A
Sbjct: 342 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT-----TKEPAPTTTKSAPTTPKEPAP 396
Query: 185 TEVGLPRPAPSARPRPPT-EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 243
T P P P P T + P + +T EP+P + P+
Sbjct: 397 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP------------- 443
Query: 244 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 303
++P + P+ TP+ PA P+ PK + P T P++ PA S+P
Sbjct: 444 ------TAPKKPAPT---TPKEPA-PTTPKEPAPTTTKEPSPTTPKE---PAPTTTKSAP 490
Query: 304 LATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPS 363
T P A +++ PT P P ++ P P P P+ P+ P+P TP
Sbjct: 491 TTTKEP-APTTTKSAPTTPKEPSPTTTK----EPAPTTPKEPA--PTTPKKPAP-TTPKE 542
Query: 364 QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATP 423
A T+ P T P+ P P T P + P P P +P P +P P
Sbjct: 543 PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT--PKKLTPTTPEKLAPTTP-EKP 599
Query: 424 SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA-TPPSQAPPSLAAPPLQVP 482
+P P LA + P P +P AP +P A+ P +P P + P+ P P
Sbjct: 600 APTTPEELAPTTPEEP--TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 657
Query: 483 PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP-GQ 541
+P + P +P T P P P + A P AP P P + P G
Sbjct: 658 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKEPTSTTCDKPAPTTPKGT 716
Query: 542 APFSPSASLPMSPLATPPPQAPPVLAAPLLQVP-PSPPASPTLQAPRRPPTPGPDTSVSG 600
AP +P P +P P P P A L+ P P+ P P + T GP ++ S
Sbjct: 717 APTTPKEPAPTTP-KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 775
Query: 601 ------PRLTLALAP---GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 651
P+ T P P P +P++ + P S+ T+T E + S E
Sbjct: 776 KPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDES 835
Query: 652 GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETE- 710
S P P A P PG P PA TE
Sbjct: 836 TPELSAEPT-------PKALENSPK-------EPGVPTTKTPAATKPEMTTTAKDKTTER 881
Query: 711 ----GPESATPAP 719
PE+ T AP
Sbjct: 882 DLRTTPETTTAAP 894
Score = 150 bits (378), Expect = 6e-36
Identities = 166/658 (25%), Positives = 231/658 (35%), Gaps = 83/658 (12%)
Query: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63
K + G A TP P TP+ P S P P TP ++ +A ++P
Sbjct: 293 KAETTTKGPALTTPKEPTP--TTPKEPASTTPKEP-TPTTIK---SAPTTPKEP------ 340
Query: 64 GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGT 123
T +SAP P A T+++ PA P PA T+ P + +++ T
Sbjct: 341 ---APTTTKSAPTT-PKEPAPTTTKEPAPTTPKE-------PAPTTTKEPAPTTTKSAPT 389
Query: 124 TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA 183
T P T + A PK A + PTP TP A
Sbjct: 390 TPKEPA----------PTTPKKPAPTTPKEPAPTTPKE-----PTPTTPKEPAPTTKEPA 434
Query: 184 GTEVGLPRPAPSARPRP--PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 241
T P P +P P P E + + +T EPSP + P+ P +
Sbjct: 435 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK 494
Query: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301
+ T S+P + T + PA + +P +P TP K+ AP P
Sbjct: 495 EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP--KEPAPTT-PKEP 551
Query: 302 SPLATPSPSAALQSQAPPTLPA-TPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPAT 360
+P T P+ + PT P T ++ TP LAP +P P P T
Sbjct: 552 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA--------PTT 603
Query: 361 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL 420
P A T+ PT P+P A P PA P AP +P P +P
Sbjct: 604 PEELAPTTPEEPTPTTPEE--PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK 661
Query: 421 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP-PVSPSATPPSQAPPSLAAP-- 477
T +P P A L+ P P P +P + P S + P+ P AP
Sbjct: 662 ET-APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 720
Query: 478 PLQVPPSPPASP-PMSPSATPP-----PQAPPPLAAPPLQLAKPPPQAPPALA------T 525
P + P+ P P P +P T P P P P +LA + P + T
Sbjct: 721 PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 780
Query: 526 PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 585
P + P+ P AP +P P +P TPPP V + P + SP
Sbjct: 781 TPKETAPTTPKE---PAPTTPKKPAPTTP-ETPPPTTSEVSTPTTTKEPTTIHKSPDEST 836
Query: 586 PRRPPTPGPDTSVSGPRLTLALAPGPP---PPPSRSPSSTLSGPDLAGHSSSATSTPE 640
P P P + P+ PG P P + P T + D T TPE
Sbjct: 837 PELSAEPTPKALENSPK-----EPGVPTTKTPAATKPEMTTTAKDKTTERDLRT-TPE 888
Score = 132 bits (332), Expect = 1e-30
Identities = 177/757 (23%), Positives = 263/757 (34%), Gaps = 109/757 (14%)
Query: 69 TIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPP-------------AKNTSPGPVS 115
T P S+ +A P A + ++ R P ++ ++N S
Sbjct: 70 TSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSS 129
Query: 116 SPGRASGTTRPGPLG---------QKGLRISAEETVARGKATEAPKRSALS-AGARRDTS 165
S +S T R QK L++ + R K PK + AG+ D
Sbjct: 130 SSSSSSSTIRKIKSSKNSAANRELQKKLKVK-DNKKNRTKKKPTPKPPVVDEAGSGLDNG 188
Query: 166 GPTPGTPSPAMARRSRAAGT-EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT---EPS 221
TP + + ++ + + ++ +P PP K S TT + +
Sbjct: 189 DFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKET 248
Query: 222 PAARRRPSAGG-----------GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS 270
++ S G +++ +++ L+ ++ L+ P P A T + PA +
Sbjct: 249 TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT---PKAETTTKGPALTT 305
Query: 271 QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSL 330
+P P TP K+ P + S+P TP A +++ PT P P
Sbjct: 306 PKEPTPTTPKEPASTTP--KEPTPTT--IKSAP-TTPKEPAPTTTKSAPTTPKEP----- 355
Query: 331 TCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA 390
P P+P+ P P+P T TT+ +PT + P+ P P
Sbjct: 356 -----APTTTKEPAPTTPKE----PAPTTTKEPAPTTTKSAPTTPKEPA--PTTPKKPAP 404
Query: 391 TPPPQAPPALALPPLQAPPSPPASPPLSPLAT----PSPQAPNALAVHLLQAPFSPPPSP 446
T P + P P P PA P T P+P AP A + P P
Sbjct: 405 TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE 464
Query: 447 PVQAPFSPPA-SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP-PMSPSATPPPQAPPP 504
P P+ + P P+ T AP + P S P +P SP+ T P P
Sbjct: 465 PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 524
Query: 505 LAAPPLQLAKPPPQAP--PALATP----------PLQALPSPPASFPGQ--APFSPSASL 550
P KP P P PA TP P P PA + AP +P
Sbjct: 525 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 584
Query: 551 PMSP--LATPPPQAP----PVLAAPLLQVPPSP-------PASPTLQAPRRPPTPGPDTS 597
P +P LA P+ P P AP P+P P +P AP P P P T+
Sbjct: 585 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP-TT 643
Query: 598 VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASP 657
P T P P P +P +T G A +TP++ P+ A +
Sbjct: 644 PKEPAPTTPKEPAPTTPKETAP-TTPKGTAPTTLKEPAPTTPKK-----PAPKELAPTTT 697
Query: 658 PPDAELAACHPAAWS-RGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESAT 716
PA + +G AP AP P P T G+A T+ E
Sbjct: 698 KEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP--TTLKEPAPTTPKK 755
Query: 717 PAPGALDPGPSPG---TSGGKAAAGAGAGASSRSPKQ 750
PAP L P + G T+ K A + +PK+
Sbjct: 756 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE 792
Score = 114 bits (285), Expect = 4e-25
Identities = 123/555 (22%), Positives = 186/555 (33%), Gaps = 49/555 (8%)
Query: 186 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL---------QR 236
EV P PS++ PP G +++ S ++ S P+ ++ + Q
Sbjct: 65 EVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQE 124
Query: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296
+S S SSS++ +S ++ K + + P PP D A +
Sbjct: 125 SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSG 184
Query: 297 GPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPS 356
+ TP S T H+ T T P PS PP+ T
Sbjct: 185 LDNGDFKVTTPDTS------------TTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKE 232
Query: 357 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPP 416
T + T T + + A ++ + +P
Sbjct: 233 TSLTVNKETTVETKETTTTNKQTSTDG---------KEKTTSAKETQSIEKTSAKDLAPT 283
Query: 417 LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 476
LA P+P+A L P P P+ P + P ++ P P+ T AP +
Sbjct: 284 SKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE----PASTTPKEPTPTTIKSAPTTPKE 339
Query: 477 PPLQVPPSPPASP-PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPP 535
P S P +P +P+ T P P P +P P + T P + P+ P
Sbjct: 340 PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 399
Query: 536 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP-PASPTLQAPRRPPTPGP 594
P P+ + P P T P + P P P P P +P AP P P P
Sbjct: 400 KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP 459
Query: 595 DTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGH-----SSSATSTPEE------LR 643
T+ P T P P P +P++T S P + SA +TP+E
Sbjct: 460 -TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE 518
Query: 644 GYDSGPEGGAAASPPPDAELAACHPAAWS-RGPAPPLAFRGAPGAPLPWPPATGPGSADG 702
+ P+ A +P A PA + + PAP + AP P P T +A
Sbjct: 519 PAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPT 578
Query: 703 LCTIYETEGPESATP 717
PE P
Sbjct: 579 TPKKLTPTTPEKLAP 593
Score = 101 bits (251), Expect = 3e-21
Identities = 155/660 (23%), Positives = 222/660 (33%), Gaps = 113/660 (17%)
Query: 13 AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPE 72
A TP AP P +P+ P P TP K A T E
Sbjct: 395 APTTPKKPAPTTPKEPAPTTPKEPTPTTP--------------KEPAPTTKEPAPTTPKE 440
Query: 73 SAPRAGPTRSAGTSSRNPAS---RPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129
AP A P + A T+ + PA + PA + P P P ++ + T P P
Sbjct: 441 PAPTA-PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 499
Query: 130 GQKGLRISAEE---TVARGKATEAPKRSALSAGARRDTSGPTPGTPS-PAMARRSRAAGT 185
K + +E T + A PK A + + P P TP PA A T
Sbjct: 500 TTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK-----PAPTTPKEPAPTTPKEPAPT 554
Query: 186 EVGLPRPAPSARPRP-----------------------PTEGPRKSVSSASEHSTT---E 219
P P P P PT + + ++ E + T E
Sbjct: 555 TTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE 614
Query: 220 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS--ARGTPRAPAHPSQPK---- 273
P+P P+ P + ++ TP PA + P A TP+ PA P+ PK
Sbjct: 615 PTPTTPEEPA-------PTTPKAAAPNTP-KEPAPTTPKEPAPTTPKEPA-PTTPKETAP 665
Query: 274 --PKGLQ--ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSS 329
PKG L+ P T P+K A L P ++ + + + T P TP +
Sbjct: 666 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 725
Query: 330 LTCQLATPLPLAPPSP--SAPPSLQ----TLPSPPATPPSQATTSLGSPTLQATHSFLPS 383
T TP AP +P +AP +L+ T P PA P A T+ PT + P+
Sbjct: 726 PT----TPKEPAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSDKPAPT 780
Query: 384 PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 443
P T P + PA P AP +P PP + + +H +P
Sbjct: 781 TPKETAPTTPKE--PAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 838
Query: 444 PS--PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV--------PPSPPASPPMSP 493
S P +A + P P V + TP + P + P + A+P M+
Sbjct: 839 LSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTK 898
Query: 494 --SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS------ 545
+ T + A Q+ Q L+ P + +
Sbjct: 899 ETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMN 958
Query: 546 -------PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS-PTLQAPRRPPTPGPDTS 597
P S TP PQ P AP P + P ++ P+ PTP TS
Sbjct: 959 KPEETAKPKDRATNSKATTPKPQKPT--KAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTS 1016
Score = 30.0 bits (66), Expect = 9.5
Identities = 40/195 (20%), Positives = 68/195 (34%), Gaps = 23/195 (11%)
Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT--RSA 83
+P+ PG P P A + L T PE+ A +A
Sbjct: 851 SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLR---------TTPETTTAAPKMTKETA 901
Query: 84 GTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVA 143
T+ + S+ A+ + ++T+P +++ TT + I+ E +
Sbjct: 902 TTTEKTTESKITATTTQVTSTTTQDTTPFKITT---LKTTTLAPKVTTTKKTITTTEIMN 958
Query: 144 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE 203
+ + T PK A ++ A TP P ++ T P+ P R T
Sbjct: 959 KPEETAKPKDRATNSKAT---------TPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTP 1009
Query: 204 GPRKSVSSASEHSTT 218
PRK S+ E + T
Sbjct: 1010 TPRKMTSTMPELNPT 1024
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 152 bits (383), Expect = 2e-36
Identities = 189/771 (24%), Positives = 269/771 (34%), Gaps = 102/771 (13%)
Query: 2 DNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAER 61
DNK+++ K + P G P T +V + KP+ R
Sbjct: 202 DNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR 261
Query: 62 AG-GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA 120
T E++ + T ++ ++ E+ AK T +S
Sbjct: 262 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 321
Query: 121 SGTTR----PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM 176
+ T++ P P ET +G A PK + ++ + TP P+P
Sbjct: 322 APTSKVLAKPTPKA---------ETTTKGPALTTPKEPTPTTP--KEPASTTPKEPTPTT 370
Query: 177 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR 236
+ + E PAP+ PT P++ + +T EP+P + P A +
Sbjct: 371 IKSAPTTPKE-----PAPTTTKSAPTT-PKEPAPT----TTKEPAPTTPKEP-APTTTKE 419
Query: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296
PA + S+ T PA + P + P P P+ PK P + P K+ AP
Sbjct: 420 PAPTTTKSAPTTPKEPAPTTPK-KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT 478
Query: 297 GPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPS 356
P +P A P+ + PT P P P PSP+ P P+
Sbjct: 479 -PKEPAPTAPKKPAPTTPKEPAPTTPKEP----------APTTTKEPSPTTPKE----PA 523
Query: 357 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT--PPPQAP--PALALPPLQAPPSPP 412
P T + TT +PT + P P SP T P P P PA P AP +P
Sbjct: 524 PTTTKSAPTTTKEPAPTTTKSAPTTPKEP-SPTTTKEPAPTTPKEPAPTTPKKPAPTTPK 582
Query: 413 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ-APFSPPASPPVSPSATPPSQAP 471
P TP AP P P P+ P + AP +P P +P P+
Sbjct: 583 EPAP----TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPE 638
Query: 472 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP--PALATPPLQ 529
P ++ P+ P P +P+ P P AA P +P P P PA TP
Sbjct: 639 KPAPTTPEELAPTTPEEP--TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 696
Query: 530 ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP------PASPTL 583
A +P + P + +L TP AP LA + P S P +P
Sbjct: 697 APTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG 756
Query: 584 QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 643
AP P P P T P P P +P+ TL P ++ P+EL
Sbjct: 757 TAPTTPKEPAPTTPKE---------PAPTTPKGTAPT-TLKEP---APTTPKKPAPKELA 803
Query: 644 GYDS-GPEGGAAASPPPDA--ELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSA 700
+ GP + P P E A P + PAP P P P P T P +
Sbjct: 804 PTTTKGPTSTTSDKPAPTTPKETAPTTP----KEPAPT-----TPKKPAPTTPETPPPTT 854
Query: 701 DGLCTIYETEGPE-------------SATPAPGALDPGP-SPGTSGGKAAA 737
+ T T+ P SA P P AL+ P PG K A
Sbjct: 855 SEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPA 905
Score = 150 bits (378), Expect = 6e-36
Identities = 171/673 (25%), Positives = 240/673 (35%), Gaps = 84/673 (12%)
Query: 71 PESAPRAGPTRSAGTSSRNPASRPPASGRGERAP-PAKNTSPGPVSSPGRASGTT--RPG 127
P S A PT A T+++ PA P PA T P + +++ TT P
Sbjct: 323 PTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPA 382
Query: 128 PLGQKGLRISAEE---TVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184
P K + +E T + A PK A + T P P T A A
Sbjct: 383 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTT-----TKEPAPTTTKSAPTTPKEPAP 437
Query: 185 TEVGLPRPAPSARPRPPT-EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 243
T P P P P T + P + +T EP+P + P+
Sbjct: 438 TTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAP------------- 484
Query: 244 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 303
++P + P+ TP+ PA P+ PK + P T P++ PA S+P
Sbjct: 485 ------TAPKKPAPT---TPKEPA-PTTPKEPAPTTTKEPSPTTPKE---PAPTTTKSAP 531
Query: 304 LATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPS 363
T P A +++ PT P P ++ P P P P+ P+ P+P TP
Sbjct: 532 TTTKEP-APTTTKSAPTTPKEPSPTTTK----EPAPTTPKEPA--PTTPKKPAP-TTPKE 583
Query: 364 QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATP 423
A T+ P T P+ P P T P + P P P +P P +P P
Sbjct: 584 PAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTT--PKKLTPTTPEKLAPTTP-EKP 640
Query: 424 SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA-TPPSQAPPSLAAPPLQVP 482
+P P LA + P P +P AP +P A+ P +P P + P+ P P
Sbjct: 641 APTTPEELAPTTPEEP--TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 698
Query: 483 PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP-GQ 541
+P + P +P T P P P + A P AP P P + P G
Sbjct: 699 TTPKETAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKEPTSTTCDKPAPTTPKGT 757
Query: 542 APFSPSASLPMSPLATPPPQAPPVLAAPLLQVP-PSPPASPTLQAPRRPPTPGPDTSVSG 600
AP +P P +P P P P A L+ P P+ P P + T GP ++ S
Sbjct: 758 APTTPKEPAPTTP-KEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 816
Query: 601 ------PRLTLALAP---GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 651
P+ T P P P +P++ + P S+ T+T E + S E
Sbjct: 817 KPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDES 876
Query: 652 GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETE- 710
S P P A P PG P PA TE
Sbjct: 877 TPELSAEPT-------PKALENSPK-------EPGVPTTKTPAATKPEMTTTAKDKTTER 922
Query: 711 ----GPESATPAP 719
PE+ T AP
Sbjct: 923 DLRTTPETTTAAP 935
Score = 150 bits (378), Expect = 6e-36
Identities = 166/658 (25%), Positives = 231/658 (35%), Gaps = 83/658 (12%)
Query: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63
K + G A TP P TP+ P S P P TP ++ +A ++P
Sbjct: 334 KAETTTKGPALTTPKEPTP--TTPKEPASTTPKEP-TPTTIK---SAPTTPKEP------ 381
Query: 64 GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGT 123
T +SAP P A T+++ PA P PA T+ P + +++ T
Sbjct: 382 ---APTTTKSAPTT-PKEPAPTTTKEPAPTTPKE-------PAPTTTKEPAPTTTKSAPT 430
Query: 124 TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA 183
T P T + A PK A + PTP TP A
Sbjct: 431 TPKEPA----------PTTPKKPAPTTPKEPAPTTPKE-----PTPTTPKEPAPTTKEPA 475
Query: 184 GTEVGLPRPAPSARPRP--PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 241
T P P +P P P E + + +T EPSP + P+ P +
Sbjct: 476 PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK 535
Query: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301
+ T S+P + T + PA + +P +P TP K+ AP P
Sbjct: 536 EPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP--KEPAPTT-PKEP 592
Query: 302 SPLATPSPSAALQSQAPPTLPA-TPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPAT 360
+P T P+ + PT P T ++ TP LAP +P P P T
Sbjct: 593 APTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA--------PTT 644
Query: 361 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL 420
P A T+ PT P+P A P PA P AP +P P +P
Sbjct: 645 PEELAPTTPEEPTPTTPEE--PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK 702
Query: 421 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP-PVSPSATPPSQAPPSLAAP-- 477
T +P P A L+ P P P +P + P S + P+ P AP
Sbjct: 703 ET-APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 761
Query: 478 PLQVPPSPPASP-PMSPSATPP-----PQAPPPLAAPPLQLAKPPPQAPPALA------T 525
P + P+ P P P +P T P P P P +LA + P + T
Sbjct: 762 PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 821
Query: 526 PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 585
P + P+ P AP +P P +P TPPP V + P + SP
Sbjct: 822 TPKETAPTTPKE---PAPTTPKKPAPTTP-ETPPPTTSEVSTPTTTKEPTTIHKSPDEST 877
Query: 586 PRRPPTPGPDTSVSGPRLTLALAPGPP---PPPSRSPSSTLSGPDLAGHSSSATSTPE 640
P P P + P+ PG P P + P T + D T TPE
Sbjct: 878 PELSAEPTPKALENSPK-----EPGVPTTKTPAATKPEMTTTAKDKTTERDLRT-TPE 929
Score = 132 bits (332), Expect = 1e-30
Identities = 177/757 (23%), Positives = 263/757 (34%), Gaps = 109/757 (14%)
Query: 69 TIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPP-------------AKNTSPGPVS 115
T P S+ +A P A + ++ R P ++ ++N S
Sbjct: 111 TSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSS 170
Query: 116 SPGRASGTTRPGPLG---------QKGLRISAEETVARGKATEAPKRSALS-AGARRDTS 165
S +S T R QK L++ + R K PK + AG+ D
Sbjct: 171 SSSSSSSTIRKIKSSKNSAANRELQKKLKVK-DNKKNRTKKKPTPKPPVVDEAGSGLDNG 229
Query: 166 GPTPGTPSPAMARRSRAAGT-EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT---EPS 221
TP + + ++ + + ++ +P PP K S TT + +
Sbjct: 230 DFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKET 289
Query: 222 PAARRRPSAGG-----------GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS 270
++ S G +++ +++ L+ ++ L+ P P A T + PA +
Sbjct: 290 TTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT---PKAETTTKGPALTT 346
Query: 271 QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSL 330
+P P TP K+ P + S+P TP A +++ PT P P
Sbjct: 347 PKEPTPTTPKEPASTTP--KEPTPTT--IKSAP-TTPKEPAPTTTKSAPTTPKEP----- 396
Query: 331 TCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA 390
P P+P+ P P+P T TT+ +PT + P+ P P
Sbjct: 397 -----APTTTKEPAPTTPKE----PAPTTTKEPAPTTTKSAPTTPKEPA--PTTPKKPAP 445
Query: 391 TPPPQAPPALALPPLQAPPSPPASPPLSPLAT----PSPQAPNALAVHLLQAPFSPPPSP 446
T P + P P P PA P T P+P AP A + P P
Sbjct: 446 TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKE 505
Query: 447 PVQAPFSPPA-SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP-PMSPSATPPPQAPPP 504
P P+ + P P+ T AP + P S P +P SP+ T P P
Sbjct: 506 PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTP 565
Query: 505 LAAPPLQLAKPPPQAP--PALATP----------PLQALPSPPASFPGQ--APFSPSASL 550
P KP P P PA TP P P PA + AP +P
Sbjct: 566 KEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT 625
Query: 551 PMSP--LATPPPQAP----PVLAAPLLQVPPSP-------PASPTLQAPRRPPTPGPDTS 597
P +P LA P+ P P AP P+P P +P AP P P P T+
Sbjct: 626 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP-TT 684
Query: 598 VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASP 657
P T P P P +P +T G A +TP++ P+ A +
Sbjct: 685 PKEPAPTTPKEPAPTTPKETAP-TTPKGTAPTTLKEPAPTTPKK-----PAPKELAPTTT 738
Query: 658 PPDAELAACHPAAWS-RGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESAT 716
PA + +G AP AP P P T G+A T+ E
Sbjct: 739 KEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP--TTLKEPAPTTPKK 796
Query: 717 PAPGALDPGPSPG---TSGGKAAAGAGAGASSRSPKQ 750
PAP L P + G T+ K A + +PK+
Sbjct: 797 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE 833
Score = 114 bits (285), Expect = 4e-25
Identities = 123/555 (22%), Positives = 186/555 (33%), Gaps = 49/555 (8%)
Query: 186 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL---------QR 236
EV P PS++ PP G +++ S ++ S P+ ++ + Q
Sbjct: 106 EVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQE 165
Query: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296
+S S SSS++ +S ++ K + + P PP D A +
Sbjct: 166 SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSG 225
Query: 297 GPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPS 356
+ TP S T H+ T T P PS PP+ T
Sbjct: 226 LDNGDFKVTTPDTS------------TTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKE 273
Query: 357 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPP 416
T + T T + + A ++ + +P
Sbjct: 274 TSLTVNKETTVETKETTTTNKQTSTDG---------KEKTTSAKETQSIEKTSAKDLAPT 324
Query: 417 LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 476
LA P+P+A L P P P+ P + P ++ P P+ T AP +
Sbjct: 325 SKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE----PASTTPKEPTPTTIKSAPTTPKE 380
Query: 477 PPLQVPPSPPASP-PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPP 535
P S P +P +P+ T P P P +P P + T P + P+ P
Sbjct: 381 PAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP 440
Query: 536 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP-PASPTLQAPRRPPTPGP 594
P P+ + P P T P + P P P P P +P AP P P P
Sbjct: 441 KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP 500
Query: 595 DTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGH-----SSSATSTPEE------LR 643
T+ P T P P P +P++T S P + SA +TP+E
Sbjct: 501 -TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE 559
Query: 644 GYDSGPEGGAAASPPPDAELAACHPAAWS-RGPAPPLAFRGAPGAPLPWPPATGPGSADG 702
+ P+ A +P A PA + + PAP + AP P P T +A
Sbjct: 560 PAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPT 619
Query: 703 LCTIYETEGPESATP 717
PE P
Sbjct: 620 TPKKLTPTTPEKLAP 634
Score = 101 bits (251), Expect = 3e-21
Identities = 155/660 (23%), Positives = 222/660 (33%), Gaps = 113/660 (17%)
Query: 13 AARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPE 72
A TP AP P +P+ P P TP K A T E
Sbjct: 436 APTTPKKPAPTTPKEPAPTTPKEPTPTTP--------------KEPAPTTKEPAPTTPKE 481
Query: 73 SAPRAGPTRSAGTSSRNPAS---RPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129
AP A P + A T+ + PA + PA + P P P ++ + T P P
Sbjct: 482 PAPTA-PKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPT 540
Query: 130 GQKGLRISAEE---TVARGKATEAPKRSALSAGARRDTSGPTPGTPS-PAMARRSRAAGT 185
K + +E T + A PK A + + P P TP PA A T
Sbjct: 541 TTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKK-----PAPTTPKEPAPTTPKEPAPT 595
Query: 186 EVGLPRPAPSARPRP-----------------------PTEGPRKSVSSASEHSTT---E 219
P P P P PT + + ++ E + T E
Sbjct: 596 TTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE 655
Query: 220 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS--ARGTPRAPAHPSQPK---- 273
P+P P+ P + ++ TP PA + P A TP+ PA P+ PK
Sbjct: 656 PTPTTPEEPA-------PTTPKAAAPNTP-KEPAPTTPKEPAPTTPKEPA-PTTPKETAP 706
Query: 274 --PKGLQ--ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSS 329
PKG L+ P T P+K A L P ++ + + + T P TP +
Sbjct: 707 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 766
Query: 330 LTCQLATPLPLAPPSP--SAPPSLQ----TLPSPPATPPSQATTSLGSPTLQATHSFLPS 383
T TP AP +P +AP +L+ T P PA P A T+ PT + P+
Sbjct: 767 PT----TPKEPAPTTPKGTAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSDKPAPT 821
Query: 384 PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 443
P T P + PA P AP +P PP + + +H +P
Sbjct: 822 TPKETAPTTPKE--PAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 879
Query: 444 PS--PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV--------PPSPPASPPMSP 493
S P +A + P P V + TP + P + P + A+P M+
Sbjct: 880 LSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTK 939
Query: 494 --SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS------ 545
+ T + A Q+ Q L+ P + +
Sbjct: 940 ETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMN 999
Query: 546 -------PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS-PTLQAPRRPPTPGPDTS 597
P S TP PQ P AP P + P ++ P+ PTP TS
Sbjct: 1000 KPEETAKPKDRATNSKATTPKPQKPT--KAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTS 1057
Score = 30.0 bits (66), Expect = 9.5
Identities = 40/195 (20%), Positives = 68/195 (34%), Gaps = 23/195 (11%)
Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT--RSA 83
+P+ PG P P A + L T PE+ A +A
Sbjct: 892 SPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLR---------TTPETTTAAPKMTKETA 942
Query: 84 GTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVA 143
T+ + S+ A+ + ++T+P +++ TT + I+ E +
Sbjct: 943 TTTEKTTESKITATTTQVTSTTTQDTTPFKITT---LKTTTLAPKVTTTKKTITTTEIMN 999
Query: 144 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE 203
+ + T PK A ++ A TP P ++ T P+ P R T
Sbjct: 1000 KPEETAKPKDRATNSKAT---------TPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTP 1050
Query: 204 GPRKSVSSASEHSTT 218
PRK S+ E + T
Sbjct: 1051 TPRKMTSTMPELNPT 1065
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 150 bits (380), Expect = 4e-36
Identities = 188/668 (28%), Positives = 244/668 (36%), Gaps = 99/668 (14%)
Query: 97 SGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA-EETVARGKATEAPKRSA 155
SG + P ++ S G S T G + + + S E RG E ++
Sbjct: 536 SGSSSSSIPESQSNHSNQSDSG-VSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKAR 594
Query: 156 LSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEH 215
+ + R TS P +P P + A+ LP P P P PP P
Sbjct: 595 MESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPP---------- 644
Query: 216 STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP-KP 274
P ++ PSAG S + T L + ++ + P P SQ KP
Sbjct: 645 --PPPPLPSQSAPSAGSAAPMFVKYS---TITRLQNASQHSGALFKPPTPPVMQSQSVKP 699
Query: 275 KGLQALRPPQ-VTPPRKDAAPALGPLSSSPLATPSPSAAL--QSQAPPTLPATPHSSSLT 331
Q L PP V PP P P S+ P+P A Q APP P H
Sbjct: 700 ---QILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPP-PLKIHQVQHI 755
Query: 332 CQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT 391
Q+A P P PP AP Q P P T P+ +T +P + +PP T
Sbjct: 756 TQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQA-----APP-----T 805
Query: 392 PPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP--NALAVHLLQAPFSPPPS--PP 447
P P PPA P A PP SPP P+ P P P + +P SP PS
Sbjct: 806 PTPPVPPAKKQPAFPASYIPP-SPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQ 864
Query: 448 VQAPFSPPASPPVSPS-------ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 500
+ + F PP +PP S A Q+PP++ A P P S P P P PPP+
Sbjct: 865 IASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFP--PPPPE 922
Query: 501 A----PPPLAAPPLQLAKPPPQAPP-ALATPPLQALP--------SPPASFPGQAPFSPS 547
+ PPP PP + PPP PP A TP P SP P P S
Sbjct: 923 SSLVFPPP---PPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNS 979
Query: 548 ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP---TLQAPRRPPTPGPDTSVSGPRLT 604
+ S P P+ P V + PP+ SP TL P PP PG ++SG L
Sbjct: 980 SIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPG-KLNLSGVNLP 1038
Query: 605 LALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELA 664
L G + P L+G + + + S P PPP+ EL
Sbjct: 1039 GVLQQG---------CVSAKAPVLSGRGK------DSVVEFPSPPSDSDFPPPPPETELP 1083
Query: 665 ACH---PAAWSRGPAPPLAFRGAPGAPLPW--------PPATGPGSADG--LCTIYETEG 711
PA +S +P +A P W PP T P D L +E
Sbjct: 1084 LPPIEIPAVFSGNTSPKVAV--VNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQ 1141
Query: 712 PESATPAP 719
P AT P
Sbjct: 1142 PTMATVVP 1149
Score = 117 bits (293), Expect = 5e-26
Identities = 166/666 (24%), Positives = 239/666 (35%), Gaps = 94/666 (14%)
Query: 14 ARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRK-------PLAERAGGIG 66
A P+ P P PP P PPPP P + +AG+ + A
Sbjct: 621 ASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHS 680
Query: 67 GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 126
GA P ++S P P +G PP P P +PG A +P
Sbjct: 681 GALFKPPTPPVMQSQSV-----KPQILVPPNGVVPPPPP-----PPPPPTPGSAMAQLKP 730
Query: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 186
P + SA P + PTP P P A A +
Sbjct: 731 APCAPSLPQFSA----------PPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPK 780
Query: 187 VGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA 246
+ PAP++ T+ V+ A+ + T P P A+++P+ P+ +
Sbjct: 781 PLVTIPAPTS-----TKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPV 835
Query: 247 TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG-PLSSSPLA 305
P + P + A+ P +P P K + + PP TPP ++ P P + +P +
Sbjct: 836 PPPTLPKQQSFCAK-PPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQS 894
Query: 306 TPSPSAALQSQ------APPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPA 359
P+ A + Q P P P SSL P P+ P P PP+ P
Sbjct: 895 PPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSG 954
Query: 360 TP--PSQATTSLGS----PTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPA 413
+P + T+S G PT Q S S S P P+ P +L PP+
Sbjct: 955 SPGKKTSKTSSPGGKKPPPTPQRNSSIKSS---SGAEHPEPKRPSVDSLVSKFTPPAESG 1011
Query: 414 SPPLS----PLATPSPQAPNALAVHL----------LQAPFSPP---------PSPPVQA 450
SP P A P P N V+L +AP PSPP +
Sbjct: 1012 SPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDS 1071
Query: 451 PFSPPASPPVSPSATPPSQAPPSLA---APPLQ-VPPSPPASPPMSPSATPPPQAPPPLA 506
F PP PP + PP + P + +P + V P P MS PPP P
Sbjct: 1072 DFPPP--PPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRND 1129
Query: 507 APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM--------SPLATP 558
+ L A+ Q P +AT Q SP +S Q F + + L++
Sbjct: 1130 STRLTQAEISEQ--PTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSR 1187
Query: 559 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 618
+A P + +PP P P L + ++ G + +SG TL P PP PP R
Sbjct: 1188 MSRAEPTATMDDMALPPPP---PELLSDQQKAGYG-GSHISG-YATLRRGP-PPAPPKRD 1241
Query: 619 PSSTLS 624
++ LS
Sbjct: 1242 QNTKLS 1247
Score = 117 bits (293), Expect = 5e-26
Identities = 115/392 (29%), Positives = 138/392 (35%), Gaps = 68/392 (17%)
Query: 382 PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 441
PSPPL P PPP PP PP PP PP PPL + PS + + V
Sbjct: 624 PSPPLPP---PPPPPPP----PP---PPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRL 673
Query: 442 PPPSPPVQAPFSPPASPPV--SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 499
S A F PP +PPV S S P PP+ PP PP PP P P
Sbjct: 674 QNASQHSGALFKPP-TPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAP 732
Query: 500 QAP--PPLAAPP-----------LQLAKPPPQAPPALATP-PLQALPSPPASFPGQAPFS 545
AP P +APP Q+A P P PP + P P QA P P + P AP S
Sbjct: 733 CAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIP--APTS 790
Query: 546 PSASLPMSPLATPPPQAPPVLAAPLLQVPPSP--PASPTLQAPRRPPTPGPDTSVSGPRL 603
P+ A PP PPV PP+ PA P P PPTP
Sbjct: 791 TKTVAPVVTQAAPPTPTPPV--------PPAKKQPAFPASYIPPSPPTP----------- 831
Query: 604 TLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL 663
P P PPP+ + S S +++ P PP E
Sbjct: 832 -----PVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPP------TPPAMES 880
Query: 664 AACHPAAWSRGPAPPLAFRGAP-----GAPLPWPPATGPGSADGLCTIYETEGPESATPA 718
P + P P A + P P+P P P L P A P
Sbjct: 881 QPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPP 940
Query: 719 PGALDPGPSPGTSG--GKAAAGAGAGASSRSP 748
P P+P SG GK + + + P
Sbjct: 941 PPPPTASPTPDKSGSPGKKTSKTSSPGGKKPP 972
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 146 bits (368), Expect = 9e-35
Identities = 166/580 (28%), Positives = 240/580 (41%), Gaps = 92/580 (15%)
Query: 247 TPLSSPARSGPSARGTPRA-------PAHPS----QPKPKGLQALR-PPQVTPPRKDAAP 294
TP P + +G P+ P P + KP G ++ PQ+ P + P
Sbjct: 380 TPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMP 439
Query: 295 ALGPLSSSPLA--------TPSPSAALQSQAPPTLPATPHSSSLTCQLATPL---PLAPP 343
L P SPL+ +P P A+ S P LPA+P +L L+ PL PL+PP
Sbjct: 440 LLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEAL--HLSRPLEESPLSPP 497
Query: 344 ---SPSAPPSLQTLPSP----PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA 396
SP +PP + SP P +PP ++ S P L+ S P P SPL+ P ++
Sbjct: 498 PEESPLSPPPESSPFSPLEESPLSPPEESPPS---PALETPLS--PPPEASPLSPPFEES 552
Query: 397 PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS-----PPV-QA 450
P L+ PP + P SPP P S L+ P ++P + ++P SPPP PP ++
Sbjct: 553 P--LSPPPEELPTSPP--PEASRLSPPPEESPMSPPPE--ESPMSPPPEASRLFPPFEES 606
Query: 451 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 510
P SPP P SP + PP + L+ PP P SPP P SP +PPP+ P +
Sbjct: 607 PLSPP--PEESPLSPPPEAS--RLSPPPEDSPMSPP--PEESP-MSPPPEVSRLSPLPVV 659
Query: 511 QLAKPPPQAPPALATPPLQALPSPPASFPGQAP---FSPSASLPMSPLATPPPQ----AP 563
PPP+ P L+ PP ++ SPP +P SP++ P A+PPP+ +
Sbjct: 660 SRLSPPPEESP-LSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSL 718
Query: 564 PVLAAPLLQVPPSPPASPTLQAPR---RPPTPGPDTSVSGPRLTLA-----LAPGP---- 611
P+ +PLL +P P P + P RP P P L+ L+P P
Sbjct: 719 PLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPC 778
Query: 612 ----PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH 667
P P SP + GP L+ +P+ + S SP P+ +
Sbjct: 779 LCAVPEEPHLSPQA--EGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQ 836
Query: 668 PAAWSRGPAPPLA-----FRGAPGAPLPWPPATGPGS--ADGLCTIYETEGPESATP--- 717
P P + P +P P P PG A ++ G S +P
Sbjct: 837 SEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLG 896
Query: 718 APGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELP 757
P +PG P + + + +G S SP+ LP
Sbjct: 897 EPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLP 936
Score = 145 bits (366), Expect = 2e-34
Identities = 219/827 (26%), Positives = 285/827 (34%), Gaps = 143/827 (17%)
Query: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRK---------- 56
KA+ G R+ A + + + P P P P AL V G
Sbjct: 351 KAQGGQTIRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPG 410
Query: 57 PLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSS 116
PL A +G A + + P A + P PP P TSP P +S
Sbjct: 411 PLQCEAKPLGKAGV-----QLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEAS 465
Query: 117 PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM 176
R S P + + + P+ S LS P P + +
Sbjct: 466 --RLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLS---------PPPESSPFSP 514
Query: 177 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS-------VSSASEHSTTEPSPAARRRPS 229
S + E P PA PP E S +S E T P P A R
Sbjct: 515 LEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASR--- 571
Query: 230 AGGGLQRPASRSLSSSATPLSSPARSGPSA-RGTPRAPAHPSQPKPKGLQALRPPQ---V 285
L P S S P SP P A R P P P P+ PP+ +
Sbjct: 572 ----LSPPPEES-PMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRL 626
Query: 286 TPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPP-- 343
+PP +D +P P SP+ +P P + S P +P PL+PP
Sbjct: 627 SPPPED-SPMSPPPEESPM-SPPPEVSRLSPLPVVSRLSPPPEE--------SPLSPPPE 676
Query: 344 -SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALAL 402
SP++PP + SP PP + TS P P SP A+PPP+ ++L
Sbjct: 677 ESPTSPPPEASRLSP---PPEDSPTS-------------PPPEDSP-ASPPPE-DSLMSL 718
Query: 403 PPLQAPPSP-PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP-FSP------ 454
P ++P P P P L P + +P HL P P SP + P SP
Sbjct: 719 PLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPC 778
Query: 455 ----PASPPVSPSATPPSQAP--------PSLAAPPLQVPPSPPASPPMSPSATPPPQAP 502
P P +SP A P +P P P L P P P + PQ+
Sbjct: 779 LCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSE 838
Query: 503 PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP--P 560
P +P P L PPL P P PGQ P LP+ P PP P
Sbjct: 839 EPCLSP----RPEESHLSPELEKPPLSPRPEKPPEEPGQCP--APEELPLFP---PPGEP 889
Query: 561 QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS 620
P+L P L P PP SP P P + P L+ L P P PP SP
Sbjct: 890 SLSPLLGEPALSEPGEPPLSPL-------PEELPLSPSGEPSLSPQLMPPDPLPPPLSPI 942
Query: 621 STLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAA-------SPPPDAELAACHPAAWSR 673
T + P A P +G DS PE AA SPPP+A
Sbjct: 943 ITAAAPP-ALSPLGELEYPFGAKG-DSDPESPLAAPILETPISPPPEANCT-------DP 993
Query: 674 GPAPPLAFRGAPGAPL---------PWPPATGPGSADGLCTIYETEGPESATPAPGALDP 724
P PP+ +PG+P+ P PP P L + + P +P P
Sbjct: 994 EPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSL--VPQNSPPSQCSP-PALPLS 1050
Query: 725 GPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLS 771
PSP + GK G A + ++ E AL+ S L S
Sbjct: 1051 VPSPLSPIGK-VVGVSDEAELHEMETEKVSEPECPALEPSATSPLPS 1096
Score = 139 bits (349), Expect = 1e-32
Identities = 201/753 (26%), Positives = 257/753 (34%), Gaps = 137/753 (18%)
Query: 25 LTPRPPGSPRPPPP----VTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT 80
L+P P SP PPP +P L P E + PE++P + P
Sbjct: 494 LSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPL----SPPPEASPLSPPF 549
Query: 81 RSAGTS---SRNPASRPPASGRGERAPPAKNTSP----GPVSSPGRASGTTRPGPLGQKG 133
+ S P S PP + R P SP P+S P AS P +
Sbjct: 550 EESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPP--FEESP 607
Query: 134 LRISAEETVARGKATEAPKRSALSAGARRDTSGP----TPGTPSPAMARRSRAAGTEVGL 189
L EE+ + P+ S LS P +P +P P ++R S
Sbjct: 608 LSPPPEES----PLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLS--------- 654
Query: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249
P P S PP E P +S E S T P P A R P +S P
Sbjct: 655 PLPVVSRLSPPPEESP---LSPPPEESPTSPPPEASRLS--------PPPEDSPTSPPPE 703
Query: 250 SSPARSGP--SARGTP--RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA 305
SPA P S P +P P +P+ P ++P ++ P L P P
Sbjct: 704 DSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEE--PHLSPRPEEPHL 761
Query: 306 TPSPSAALQSQAP--PTLPATPHSSSLTCQLATP--------LPLAPPSPSAPPSLQTLP 355
+P S P P L A P L+ Q P L L+P + P L +P
Sbjct: 762 SPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEE--PHLSPVP 819
Query: 356 SPPATPPSQATTSLG--------SPTLQATHSF--LPSPPLSPLATPPPQAPPALALPPL 405
P P + L SP + +H L PPLSP PP+ P P
Sbjct: 820 EEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEE 879
Query: 406 QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP-PVQAPFSPPASPPVSPSA 464
PP P LSPL L L P PP SP P + P SP P +SP
Sbjct: 880 LPLFPPPGEPSLSPL----------LGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQL 929
Query: 465 TPPSQAPPSL------AAPPL----------------QVPPSPPASPPMSPSATPPPQAP 502
PP PP L AAPP P SP A+P + +PPP+A
Sbjct: 930 MPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEAN 989
Query: 503 -------PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 555
PP+ PP + P +P + P Q P S Q S P PL
Sbjct: 990 CTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPL 1049
Query: 556 ATPPPQAP--PVLA----APLLQVPP---SPPASPTLQAPRRPPTPGPDTSVSGPRLTLA 606
+ P P +P V+ A L ++ S P P L+ P P P +S P
Sbjct: 1050 SVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCP----- 1104
Query: 607 LAPGPPPPPS-----RSPSSTLSGPDLAGHSSSATSTP----EELRGYDSGPEGGAAASP 657
AP P P ++ L G D G TP EL+G + A
Sbjct: 1105 -APSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPV 1163
Query: 658 PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLP 690
P C A P AP AP P
Sbjct: 1164 TPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTP 1196
Score = 116 bits (290), Expect = 1e-25
Identities = 187/695 (26%), Positives = 243/695 (34%), Gaps = 97/695 (13%)
Query: 222 PAARRRPSAGGGLQRPASRSLSS----SATPLSSPARSGPSARGTPRAPAHPSQPKPKGL 277
PAA + P A+ ++ + + ++ + G AR T R H P G
Sbjct: 2053 PAADKAPYLQKAKDNRAAHRINKVQKQAESQINKQTKVGDIARKTDRPALHLRIPPQPGA 2112
Query: 278 QALRPPQVTP---------PRKDAAPALGPLSSSPLATPSPSAA--LQSQAPPTLPATPH 326
PP P P + A G L + P P + L + PP +PA
Sbjct: 2113 LGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVP 2172
Query: 327 SSSLTCQLATPLPLAPPSPSAPPSLQTLPSP---PATPPSQATTSL-GSPTLQATHSFLP 382
S LA PL P P+APP+ PSP PA PP +S G+ H+ P
Sbjct: 2173 SQD-PFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPP 2231
Query: 383 SPPLSPLATPPPQAPPAL-ALPPLQAPPSPPAS--PPLSPLATPSPQAPNALAVHLLQAP 439
P +TP P P +L L P SP PL +P P + A+ + +
Sbjct: 2232 GTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEE 2291
Query: 440 F---SPPPSPPVQAPFSPPAS----------------PPVSPSATPPSQAPPSLAAPPLQ 480
SP PP P+S P++P A+ P L P +
Sbjct: 2292 LGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQE 2351
Query: 481 VPPSPPA--SPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASF 538
PP+ SPP P P P A PPL P PQ P PP PP S
Sbjct: 2352 PPPAQALAPSPPSHPDIFRPGSYTDPYAQPPL---TPRPQPP-----PPESCCALPPRSL 2403
Query: 539 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP---RRPPTPGPD 595
P PFS + P S ++ P P L+A PS P +P Q+P RPP
Sbjct: 2404 PSD-PFSRVPASPQSQSSSQSPLTPRPLSAEAF--CPS-PVTPRFQSPDPYSRPP----- 2454
Query: 596 TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAA 655
S P+ AP PP + P LA S A P L +G
Sbjct: 2455 ---SRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVP 2511
Query: 656 SPPPDAELAACHPAAWSRGPAP-PLAFRGAPGAPLPWPPATGPG--SADGLCTIY---ET 709
S P + + A+ P+P F A G P PP PG G+ + + T
Sbjct: 2512 SGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPT 2571
Query: 710 EG-PESA--TPAPGALDPGPSP-GTSGGKAAAGAGAG---ASSRSPKQARLGELPL---G 759
G P+S T A G P SP G S G G S P A G LP G
Sbjct: 2572 LGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHG 2631
Query: 760 ALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAALSDAEL------GR 813
A Q S + T + E G G AE G + LS EL R
Sbjct: 2632 ASQRSGI------TSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQR 2685
Query: 814 WAELLSPLDESRASI--TSVTSFSPDDVASPQGDW 846
ELL R ++ T+ + P G W
Sbjct: 2686 LRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSW 2720
Score = 85.1 bits (209), Expect = 2e-16
Identities = 206/809 (25%), Positives = 265/809 (32%), Gaps = 124/809 (15%)
Query: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE-----R 61
+ K G AR A L P PG+ PPP + + G A+
Sbjct: 2087 QTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPP 2146
Query: 62 AGGIGGATIP-ESAPRAGPTRSAGTSSRNPASRPPA---SGRGERAPPAKNTSPGPVSSP 117
AG + G P E + P A S++P PA R APP P P +P
Sbjct: 2147 AGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAP 2206
Query: 118 GR---ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSP 174
+ ++RPG GQ G T G P T P P
Sbjct: 2207 AQPPMLGASSRPG-AGQPG----EFHTTPPGTPRHQP-----------STPDPFLKPRCP 2250
Query: 175 AMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEH-STTEPSPAARRRPSAGGG 233
++ + VG + + PP RK++ E + PS P G
Sbjct: 2251 SLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYG----PPNLGF 2306
Query: 234 LQRPASRSLSSSATPLSSPARSGPSARGTPRAP-AHPSQPKPKGLQALRPPQVTPPRKDA 292
+ P SS T L P P P A +P+ GL LR PQ PP +
Sbjct: 2307 VDSP------SSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGL-GLR-PQEPPPAQAL 2358
Query: 293 APALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAP-PSPSAPPSL 351
AP +PP+ P S T A P PL P P P P S
Sbjct: 2359 AP----------------------SPPSHPDIFRPGSYTDPYAQP-PLTPRPQPPPPESC 2395
Query: 352 QTLP--SPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP-PLQAP 408
LP S P+ P S+ S S + ++ S L PLS A P P P P P
Sbjct: 2396 CALPPRSLPSDPFSRVPASPQSQS--SSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRP 2453
Query: 409 PSPPAS-PPLSPL-ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 466
PS P S P +PL P PQ P V + P + PA P A
Sbjct: 2454 PSRPQSRDPFAPLHKPPRPQPPE---VAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKV 2510
Query: 467 PSQAPPSLAAPP----LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA--- 519
PS PP+ P PSP P A P PP+ P L PPP
Sbjct: 2511 PSGQPPNFVRSPGTGAFVGTPSPMRF--TFPQAVGEPSLKPPVPQPGL----PPPHGINS 2564
Query: 520 ----PPALATPPLQALPSPPASF-PGQAPFSPSA-----SLPMSPLATP---PPQAPPVL 566
P L P +F P +P PS+ S +SPL P PP AP
Sbjct: 2565 HFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDG- 2623
Query: 567 AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 626
+ P L S + T +R P T + G L A PG P S T
Sbjct: 2624 SLPYLSHGASQRSGITSPVEKR---EDPGTGM-GSSLATAELPGTQDPGMSGLSQTELEK 2679
Query: 627 DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPG 686
++++ E AA+ A A P +W P+ P AF
Sbjct: 2680 QRQRQRLRELLIRQQIQRNTLRQEKETAAA----AAGAVGPPGSWGAEPSSP-AFEQLSR 2734
Query: 687 APLPWPPATGPGSADGLCTIYETEGP---ESATPAPGALDPGPSPGTS-----GGKAAAG 738
P+ S GL + GP + P+ L P P T + G
Sbjct: 2735 GQTPFAGTQDKSSLVGL-PPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVG 2793
Query: 739 AGAGASSRSPKQARLGELPLGALQASVVQ 767
R+P G LPL Q + Q
Sbjct: 2794 GSQAFYQRAPYP---GSLPLQQQQQQLWQ 2819
Score = 75.5 bits (184), Expect = 2e-13
Identities = 184/794 (23%), Positives = 262/794 (32%), Gaps = 174/794 (21%)
Query: 11 GAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70
GA++R P A PG PPG+PR P L+ R + +
Sbjct: 2213 GASSR-PGAGQPGEFHTTPPGTPRHQPSTPDPFLK--------------PRCPSLDNLAV 2257
Query: 71 PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKN-----TSP-------GPVSSPG 118
PES P G G + P PP G +A K +SP G V SP
Sbjct: 2258 PES-PGVG-----GGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSP- 2310
Query: 119 RASGTTRPG-----------PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGP 167
+SGT G PL + ++ + + E P AL+
Sbjct: 2311 -SSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIF 2369
Query: 168 TPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 227
PG+ + A+ + P + PR P V ++ + ++ SP R
Sbjct: 2370 RPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRP 2429
Query: 228 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 287
SA P + S P S P S P +R P AP H P+P+ PP+V
Sbjct: 2430 LSAEAFCPSPVTPRFQSP-DPYSRPP-SRPQSRD-PFAPLH-KPPRPQ------PPEVAF 2479
Query: 288 PRKDAAPALGPLSSSPLATPS-PSAALQSQAPPTLPAT-PHSSSLTCQLATPLPLAPPSP 345
A P A P+ P+ L ++ P P S + TP P+ P
Sbjct: 2480 KAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFP 2539
Query: 346 SA--PPSLQT-LPSPPATPPSQATTSLG-SPTLQ---------ATHSFLPS--------- 383
A PSL+ +P P PP + G PTL AT +F PS
Sbjct: 2540 QAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSG 2599
Query: 384 --------PPLSPLATPPPQAPPALALPPLQAPPSPPA--SPPLSPLATPSPQAPNALAV 433
PL P + PP AP +LP L S + + P+ P ++LA
Sbjct: 2600 STGESYGLSPLRPPSVLPPPAPDG-SLPYLSHGASQRSGITSPVEKREDPGTGMGSSLAT 2658
Query: 434 HLLQAPFSPPPSPPVQ---------------------------------APFSPPASPPV 460
L P S Q A + PP
Sbjct: 2659 AELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPG 2718
Query: 461 SPSATPPSQAPPSLA------------APPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 508
S A P S A L+ + + +PPS + P + P + P
Sbjct: 2719 SWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDD-------- 2770
Query: 509 PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 568
+L++PPP A P+ + L +F +AP+ SLP+ Q AA
Sbjct: 2771 --RLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPY--PGSLPLQQQQQQLWQQQQATAA 2826
Query: 569 PLLQVPPSP--PASPTLQAPRR----------PPTPGPDTSVSGP-----------RLTL 605
++ S P++P + R+ PGP V GP +
Sbjct: 2827 TSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQK 2886
Query: 606 ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL-A 664
L PG P P + P ++ PE LRG S PP EL
Sbjct: 2887 GLGPGGTPFPGQGPPQRPRFYPVS--EDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNN 2944
Query: 665 ACHPAAWSRGPAPP 678
+ HP ++GP P
Sbjct: 2945 SLHPTPHTKGPTLP 2958
Score = 72.0 bits (175), Expect = 2e-12
Identities = 138/555 (24%), Positives = 180/555 (32%), Gaps = 85/555 (15%)
Query: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
P +R P R P +P PP P V AG+ LA + G GG A
Sbjct: 2449 PYSRPPSRPQSRDPFAPLHKPP-RPQPPEVAFKAGS-----LAHTSLGAGGFPAALPAGP 2502
Query: 77 AGPTRSAGTSSRNPAS-RPPASGRGERAP-PAKNTSPGPVSSPGRASGTTRPGPLGQKGL 134
AG + S + P R P +G P P + T P V P +PG G+
Sbjct: 2503 AGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGI 2562
Query: 135 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL-PRPA 193
GK P+ + + +P PS S + G GL P
Sbjct: 2563 NSHFGPGPTLGK----PQSTNYTVATGNFHPSGSPLGPS------SGSTGESYGLSPLRP 2612
Query: 194 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253
PS P P +G +S + + SP +R G + SS P
Sbjct: 2613 PSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTG---------MGSSLATAELPG 2663
Query: 254 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT--------PPRKDAAPALGPLSSSPLA 305
P G + + + + + L Q+ AA A+GP S
Sbjct: 2664 TQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAE 2723
Query: 306 TPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTL--PSPPATPPS 363
SP+ S+ T SSL + L P + PS L P PPATP S
Sbjct: 2724 PSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSS 2783
Query: 364 QATTSL----GSPTLQATHSFLPSPPLSPLATPPPQ--------APPALALPPLQAPPSP 411
S GS QA + P P PL Q A ++ PS
Sbjct: 2784 MDVNSRQLVGGS---QAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPST 2840
Query: 412 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS-----------------P 454
P P L A SP A + L P P P P A F P
Sbjct: 2841 PG-PELGRQALGSPLAGISTR---LPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFP 2896
Query: 455 PASPPVSPSATPPSQAPPSLAAP----------PLQVPPSPPASPPMSPSATPPPQAPPP 504
PP P P S+ P LA P Q P +PPA P ++ S P P P
Sbjct: 2897 GQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPA-PELNNSLHPTPHTKGP 2955
Query: 505 LAAPPLQLAKPPPQA 519
L+L PP +
Sbjct: 2956 TLPTGLELVNRPPSS 2970
Score = 67.0 bits (162), Expect = 7e-11
Identities = 148/584 (25%), Positives = 191/584 (32%), Gaps = 130/584 (22%)
Query: 126 PGPLGQKGLRISAEETVA----RGKATEAPKR---SALSAGARRDTSGPTPGTPSPAMAR 178
PG LG L E+ +ATE P L+ G ++ PG P+++
Sbjct: 4012 PGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSG 4071
Query: 179 RSRAAGTEVGLPRPAPSA-RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 237
S+ + P+P PS+ + +PP P + S T AGGG
Sbjct: 4072 DSQLLLVQPQ-PQPQPSSLQLQPPLRLPGQQQQQVSLLHT------------AGGGSHGQ 4118
Query: 238 ASRSLSSSATPLSSPARSGPSARGTPRAPAHPS-----QPKPKGLQALRPPQVTPPRKDA 292
SS A+ + P A PS QP L P Q R
Sbjct: 4119 LGSGSSSEASSV-------------PHLLAQPSVSLGDQPGSMTQNLLGPQQPMLER--- 4162
Query: 293 APALGPLSSSPLATPSPSAALQS-QAPPTLPATPHSSSLTCQLATPLPLAPP----SPSA 347
P P P P LQS Q P + P L QL L P SP
Sbjct: 4163 -PMQNNTGPQP---PKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQ 4218
Query: 348 PPSLQTL-------------PSPPATPPSQATTSL-GSPTLQATHSFLPSPPLSPL---- 389
LQ L +PP P T+ L G Q P P PL
Sbjct: 4219 QQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELG 4278
Query: 390 ATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 449
A P PQ PP L P+PP + P+ P VH +PPPS P +
Sbjct: 4279 AGPRPQGPPRL--------PAPPGALSTGPVLGP---------VHP-----TPPPSSPQE 4316
Query: 450 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP-PMSPSATPPPQAPPPLAAP 508
P P PS P SQ P Q+PP+ P +P P P+ PPP P AA
Sbjct: 4317 -----PKRPSQLPS--PSSQLPTE-----AQLPPTHPGTPKPQGPTLEPPPGRVSPAAA- 4363
Query: 509 PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 568
Q L + L P Q P S+ +P P
Sbjct: 4364 ---------QLADTLFSKGLGPWDPPDNLAETQKP-EQSSLVPGHLDQVNGQVVPEASQL 4413
Query: 569 PLLQVPPSPPASPTLQAPRR----PPTPGPDTS----VSGPR------LTLALAPGPPPP 614
+ Q P P + Q+ +R P P TS ++GPR L L
Sbjct: 4414 SIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQ 4473
Query: 615 PSRSPSSTLSGPDLAGH-SSSATSTPEELRGYDSGPEGGAAASP 657
S S ++ GH S ++L+G S E AA P
Sbjct: 4474 LSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKP 4517
Score = 66.2 bits (160), Expect = 1e-10
Identities = 167/690 (24%), Positives = 228/690 (33%), Gaps = 118/690 (17%)
Query: 16 TPAARAP--GLLTPRPPGSPRP------PPP--VTPAALRVLGAAGAVGRKP------LA 59
+P+++ P L P PG+P+P PPP V+PAA ++ + G P LA
Sbjct: 4325 SPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLA 4384
Query: 60 ERAGGIGGATIPESAPRAG----PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG-PV 114
E + +P + P S + + P P A G A K + G P+
Sbjct: 4385 ETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALG----AQSVKREANGEPI 4440
Query: 115 SSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG-------- 166
+PG ++ GP + G + + + R K + S G R + +G
Sbjct: 4441 GAPGTSNHLLLAGPRSEAGHLLL--QKLLRAKNVQLSTGRG-SEGLRAEINGHIDSKLAG 4497
Query: 167 ---PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPA 223
GTPS + AA + P+P + RK + +E
Sbjct: 4498 LEQKLQGTPS----NKEDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLK 4553
Query: 224 ARRRPSAGGGLQRPASRSLSSSATPLSS--PARSGPSARGT------PRAPAHPSQPKPK 275
++ + L PA + S P S P RG P P + SQ K
Sbjct: 4554 QLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTK 4613
Query: 276 GLQALRP------PQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSS 329
+ P P PP G S L AA + L T S
Sbjct: 4614 NNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKS 4673
Query: 330 LTCQLATPLPL----------APPSPSAPPSLQTLPSPPATPPSQATT--SLGSPTL-QA 376
L A P P + +P S+ SP + +A LGS Q
Sbjct: 4674 LDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQE 4733
Query: 377 THSFLPSPPLSPLATPP--PQAPPALALPPLQAPPSPPASP-------PLSPLATPSPQA 427
+ P PL P A+ P P P AL L+ P P + +S + T S A
Sbjct: 4734 DRALSPVIPLIPRASIPVFPDTKPYGALG-LEVPGKLPVTTWEKGKGSEVSVMLTVSAAA 4792
Query: 428 PNAL-----AVHLLQAPFSPP------PSPPVQAPFSPPASPPVSPSATP-------PSQ 469
L AV L + P P P +A P P P
Sbjct: 4793 AKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDT 4852
Query: 470 APPSLAAPPLQVPPSPPASP--------PMSPSATPPPQAPPPLAAPPL---QLAKPPPQ 518
P L +P S SP+ PP Q L QL+ PPP+
Sbjct: 4853 GPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPE 4912
Query: 519 APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 578
P +PP PSP A P P P LP PLA PP +P LA+ P P
Sbjct: 4913 EP----SPP----PSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPR 4964
Query: 579 ASPTLQA-PRRPPTPGPDTSVSGPRLTLAL 607
A P + RPP V RL L L
Sbjct: 4965 ARPPEEGEDSRPPRLKKWKGVRWKRLRLLL 4994
Score = 64.3 bits (155), Expect = 5e-10
Identities = 164/715 (22%), Positives = 226/715 (31%), Gaps = 149/715 (20%)
Query: 27 PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTS 86
PRP G PR P P P AL G V P P S+P+ P R +
Sbjct: 4281 PRPQGPPRLPAP--PGALSTGPVLGPVHPTP-------------PPSSPQE-PKRPSQLP 4324
Query: 87 SRNPASRPPASGRGERAPPAKNTSPGPV--SSPGRAS--GTTRPGPLGQKGLRISAEETV 142
S P+S+ P + P GP PGR S L KGL +
Sbjct: 4325 S--PSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGL--GPWDPP 4380
Query: 143 ARGKATEAPKRSALSAGARRDTSGP-TPGTPSPAMARRSR----AAGTEV------GLPR 191
T+ P++S+L G +G P ++ + R A G + G P
Sbjct: 4381 DNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPI 4440
Query: 192 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 251
AP GPR GL+ + + S L
Sbjct: 4441 GAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQ 4500
Query: 252 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK-------DAAPAL-----GPL 299
+ PS + A P PKPK +Q V+ +K A+ AL L
Sbjct: 4501 KLQGTPSNK-EDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQEL 4559
Query: 300 SSSPLATPSPSAALQSQAP-------------------PTLPATP-HSSSLTCQLATPLP 339
S PL P+ +A AP LP P + S L + P
Sbjct: 4560 SLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNP 4619
Query: 340 LAPPS---PSAPPSLQTLPSPPATP-------PSQATTSLGSP-TLQATHSFLPSPPLSP 388
PPS P+ PPS+Q TP P A ++ S L+ T L+
Sbjct: 4620 PTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAA 4679
Query: 389 LATPPPQAPPALALPPLQAPPSP----PASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 444
L TPP + + + SP PAS P S L +P+ P+ + Q + P
Sbjct: 4680 LPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALSP 4739
Query: 445 SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 504
P+ S P P P + P L + S ++ SA
Sbjct: 4740 VIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGV 4799
Query: 505 L-AAPPLQLAKPP-------PQAPPALATPPLQALPSPP--------------------- 535
+ A L K P P++P T P + P
Sbjct: 4800 MVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQ 4859
Query: 536 --ASFPG-----------------QAPFSPS--------ASLPMSPLATPPPQAPPVLAA 568
A PG AP P+ ++L + L+ PPP+ P +
Sbjct: 4860 FDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPS 4919
Query: 569 PLLQVPPSPPASPTLQAP----RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 619
PL P SPP P ++ P PP P P S P P P +R P
Sbjct: 4920 PLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPE------SARPKPRARPP 4968
Score = 57.0 bits (136), Expect = 7e-08
Identities = 102/394 (25%), Positives = 141/394 (35%), Gaps = 53/394 (13%)
Query: 68 ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSP----GPVSSPGRASGT 123
AT S + GP + GT+ + A+ P GE P S P P +S
Sbjct: 4037 ATEGPSTHQGGPL-AIGTTPESMATEP-----GEVKPSLSGDSQLLLVQPQPQPQPSSLQ 4090
Query: 124 TRPGPL---GQKGLRISAEETVARGKATEAPKRSALSAG------ARRDTS-GPTPGTPS 173
+P PL GQ+ ++S T G + S+ A A+ S G PG+ +
Sbjct: 4091 LQP-PLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMT 4149
Query: 174 PAMARRSRAAGTEVGLPRPAPS-ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG 232
+ + L RP + P+PP GP P+ R G
Sbjct: 4150 QNLLGPQQPM-----LERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGV 4204
Query: 233 GLQRPASRSLSSS------ATPLSSPARSGPSARGTPRAPAHPSQPKP-KGLQALRPPQV 285
+ P R LS A + + + R TP +Q P +GL +P
Sbjct: 4205 LAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLG 4264
Query: 286 TPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSP 345
P P GPL A P P Q PP LPA P + L+T L P P
Sbjct: 4265 GFP----GPQTGPLQELG-AGPRP------QGPPRLPAPPGA------LSTGPVLGPVHP 4307
Query: 346 SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA--LP 403
+ PPS P P+ PS ++ L TH P P L PP + PA A
Sbjct: 4308 TPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLAD 4367
Query: 404 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 437
L + P PP + T P+ + + HL Q
Sbjct: 4368 TLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQ 4401
Score = 55.5 bits (132), Expect = 2e-07
Identities = 110/431 (25%), Positives = 145/431 (33%), Gaps = 74/431 (17%)
Query: 340 LAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA--- 396
L P P+ P LQ SP A P+ T T+ P +S AT P
Sbjct: 3997 LGPGMPAKP--LQHFSSPGALGPTLLLTGKEQNTVD--------PAVSSEATEGPSTHQG 4046
Query: 397 --------PPALALPPLQAPPSPPASPPLSPLATPSPQA-PNALAVHLLQAPFSPPPSPP 447
P ++A P + PS L L P PQ P++L LQ P P
Sbjct: 4047 GPLAIGTTPESMATEPGEVKPSLSGDSQLL-LVQPQPQPQPSSLQ---LQPPLRLPGQQQ 4102
Query: 448 VQAPFSPPASPPV-----SPSATPPSQAPPSLAAPPLQVPPSPPASP-----PMSPSATP 497
Q A S S++ S P LA P + + P + P P
Sbjct: 4103 QQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLER 4162
Query: 498 PPQ----APPPLAAPPLQLAKPPPQAPPALATPPLQA-LPSPPASFPGQAPFSPSASLPM 552
P Q PP P LQ + P L+A L A P SP +
Sbjct: 4163 PMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQL 4222
Query: 553 SPLA-------------TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVS 599
L TPP Q P +PL + P PGP T
Sbjct: 4223 QALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGF--------PGPQT--- 4271
Query: 600 GPRLTLALAPGPPPPPS--RSPSSTLSGPDLAG-HSSSATSTPEELRGYDSGPEGGAAAS 656
GP L P P PP P + +GP L H + S+P+E + P ++
Sbjct: 4272 GPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPS--PSSQ 4329
Query: 657 PPPDAELAACHPAAWS-RGPA---PPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGP 712
P +A+L HP +GP PP A + G G D + ET+ P
Sbjct: 4330 LPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKP 4389
Query: 713 ESATPAPGALD 723
E ++ PG LD
Sbjct: 4390 EQSSLVPGHLD 4400
Score = 37.7 bits (86), Expect = 0.046
Identities = 73/298 (24%), Positives = 96/298 (32%), Gaps = 51/298 (17%)
Query: 458 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP-LQLAKPP 516
P VS AT + P + PL + +P + AT P + P L+ L L +P
Sbjct: 4031 PAVSSEAT---EGPSTHQGGPLAIGTTPESM------ATEPGEVKPSLSGDSQLLLVQPQ 4081
Query: 517 PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM---------SPLATPPPQAPPVLA 567
PQ P+ LQ PP PGQ S S ++ P +LA
Sbjct: 4082 PQPQPS----SLQL--QPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLA 4135
Query: 568 APLLQVPPSP---------PASPTLQAPRR------PPTPGPDTSVSGPRLTLALAPGPP 612
P + + P P P L+ P + PP PGP + + P
Sbjct: 4136 QPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVG 4195
Query: 613 PPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA-CHPAAW 671
++ P L S + L + A PP E P
Sbjct: 4196 QLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQG 4255
Query: 672 SRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG 729
G P L G PG P TGP G +GP PGAL GP G
Sbjct: 4256 LLGCQPQLG--GFPG------PQTGPLQELGAGP--RPQGPPRLPAPPGALSTGPVLG 4303
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 144 bits (364), Expect = 3e-34
Identities = 220/877 (25%), Positives = 292/877 (33%), Gaps = 203/877 (23%)
Query: 28 RPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSS 87
RPP P PP P P G A + + AT + +G S
Sbjct: 507 RPPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGS 566
Query: 88 RNPASRPPASGRGERAPPAKNTSPGPVSS-------PGRASGTTRPGPLGQKGLRISAEE 140
RPP G G A P+K T P+ P G PGP + A
Sbjct: 567 TAGPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGP------SVIAAP 620
Query: 141 TVARGKATEA----PKRSALSAGARRDTSGPTP----GTPSPAMARRSRAAGTEVGLP-- 190
G + P + G R S P P G P+ ++R + T V P
Sbjct: 621 PSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVS 680
Query: 191 -RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249
P P A PT G ++ + + + TE +R + G+ S S++AT
Sbjct: 681 STPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSP 740
Query: 250 SSPARSGPSARGTPRAPAHPSQ----------PKPKGLQALR---PPQVTPPRKDAAPAL 296
+ +GP +APA + P P +Q + P T A
Sbjct: 741 APHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAGAGS 800
Query: 297 GPLSSSPLATPSPSAA------------------------LQSQAPPTLPATPHSSSLTC 332
GP PL P A + AP T A P + T
Sbjct: 801 GPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTT 860
Query: 333 QLATPLP---------LAPPSPSAP-PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLP 382
+ LP LA +P+ P LQ++PS P P +Q+ + + +P + LP
Sbjct: 861 SIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPP-PKAQSVSPVQAPPPGGSAQLLP 919
Query: 383 SPPLSPLATPPPQA-------PPALALPPLQAP----PSPPAS----------------P 415
L PLA P P L PP P PP+ P
Sbjct: 920 GKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVP 979
Query: 416 PLSPLATPSPQA-------PNALAV--------HLLQAPFSPP----------------- 443
PLSP P P + P++ + H L SP
Sbjct: 980 PLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPTSSVA 1039
Query: 444 -------PSPPV---------QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV------ 481
PS P QAP P VSP +P Q PP+ AAP V
Sbjct: 1040 LGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSP--QLPPACAAPGGPVITAFYS 1097
Query: 482 -PPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP-----PQAPPALATPPLQALPSPP 535
P+P +S P++ P QAPP L PP P+ PPA AT A P+P
Sbjct: 1098 GSPAPTSSAPLAQ----PSQAPPSLVYTVATSTTPPAATILPKGPPAPAT----ATPAPT 1149
Query: 536 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP----PSPPASPTLQAPRRPPT 591
+ FP S + SL P P+AP + A + +P + + APR+P
Sbjct: 1150 SPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLE 1209
Query: 592 PGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 651
PGP + P L P PP PP + T + SS P E R GPE
Sbjct: 1210 PGPVREPTAPESELEGQPTPPAPPPLPETWTPT-----ARSSPPLPPPAEERTSAKGPET 1264
Query: 652 GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEG 711
A+ P ++ W R P L RG P P P PA P A G G
Sbjct: 1265 MASKFPSSSSD--------W-RVPGQGLENRGEP--PTPPSPAPAPAVAPG--------G 1305
Query: 712 PESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP 748
++ A D T K AAG G R P
Sbjct: 1306 SSESSSGRAAGD------TPERKEAAGTGKKVKVRPP 1336
Score = 139 bits (351), Expect = 9e-33
Identities = 203/741 (27%), Positives = 270/741 (36%), Gaps = 137/741 (18%)
Query: 11 GAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70
G AR P+A AP L P P PAA V V P+ + +
Sbjct: 642 GGGARVPSAPAPSLAYGAPAA-----PLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGR 696
Query: 71 PESAPR--AGPTRSAGTSSRNPASRP-PASGRGERAPPAKNTSPGPVSSPGRASGTTRPG 127
E++P AG GT SR P P S A TSP P G GT
Sbjct: 697 AEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKA 756
Query: 128 PLGQKGLRIS----------AEETVARGKATEAPKRSALSAGARRDTSGPTP-GTPSP-A 175
P L + A + +A+G A + AGA +GP P G P A
Sbjct: 757 PATVTNLLVGTPGYGAPAPPAVQFIAQG-APGGGTTAGSGAGAGSGPNGPVPLGILQPGA 815
Query: 176 MARRSRAAGTEVGLP------RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPS 229
+ + + LP + AP+ P P T+ S P+P R +
Sbjct: 816 LGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPS----------GPAPTTSIRFT 865
Query: 230 AGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ-PKPKGLQALRPPQVTPP 288
G +++ TP +S PSA P Q P P G L P +V P
Sbjct: 866 LPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVP 925
Query: 289 RKDAAPAL-----GPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPP 343
AAP++ G PL +P S +Q+ A P S QL TP+P++ P
Sbjct: 926 L--AAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPP--------SKIIQL-TPVPVSTP 974
Query: 344 SPSAPP-SLQTLPSPPATP-----PSQAT---------------TSLGSPTLQATHSFLP 382
S PP S TLP P + P PS TS S S+ P
Sbjct: 975 SGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGP 1034
Query: 383 SPPLSPLATPPPQAPPALALPPL---QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 439
+ ++ T + PA P L QAP P +SP+ PSPQ P A A
Sbjct: 1035 TSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPV--PSPQLPPACAA------ 1086
Query: 440 FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA--APPLQVPPSP---PASPPMSPS 494
P P + A +S +P S PSQAPPSL PP+ P PP +
Sbjct: 1087 ---PGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPAT 1143
Query: 495 ATPPPQAPPP----------LAAPPLQLAKPPPQAPP----ALATPPLQALPSPPASFPG 540
ATP P +P P L AP Q +P P+AP A+A+ P+ + + + PG
Sbjct: 1144 ATPAPTSPFPSATAGSMTYSLVAPKAQ--RPSPKAPQKVKAAIASIPVGSFEAGASGRPG 1201
Query: 541 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD---TS 597
AP P L P+ P + P PP P + T A PP P P TS
Sbjct: 1202 PAPRQP---LEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEERTS 1258
Query: 598 VSGPRLTLALAPG-----------------PPPPPSRSPSSTLS--GPDLAGHSSSATST 638
GP + P PP PPS +P+ ++ G + +A T
Sbjct: 1259 AKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDT 1318
Query: 639 PEELRGYDSGPEGGAAASPPP 659
PE +G + PPP
Sbjct: 1319 PERKEAAGTGKK--VKVRPPP 1337
Score = 139 bits (349), Expect = 1e-32
Identities = 214/851 (25%), Positives = 291/851 (34%), Gaps = 159/851 (18%)
Query: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
L P PPG P PP G A + + AT + +G
Sbjct: 510 LDPEPPGPPDPPVAFGK------GYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESG 563
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPV-------SSPGRASGTTRPGPLGQKGLRIS 137
S RPP G G A P+K T P+ P G PGP +
Sbjct: 564 QGSTAGPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGP------SVI 617
Query: 138 AEETVARGKATEA----PKRSALSAGARRDTSGPTP----GTPSPAMARRSRAAGTEVGL 189
A G + P + G R S P P G P+ ++R + T V
Sbjct: 618 AAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVR 677
Query: 190 P---RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA 246
P P P A PT G ++ + + + TE +R + G+ S S++A
Sbjct: 678 PVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAA 737
Query: 247 TPLSSPARSGPSARGTPRAPAHPSQ----------PKPKGLQAL---RPPQVTPPRKDAA 293
T + +GP +APA + P P +Q + P T A
Sbjct: 738 TSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAG 797
Query: 294 PALGPLSSSPLATPSPSAALQ----SQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPP 349
GP PL P A + +Q LP P L +AP AP
Sbjct: 798 AGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQ----------LQVAPAPAPAPG 847
Query: 350 SLQTLPSPPATPPS-----QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPP--ALAL 402
+ PS PA S TS L AT P+P + P+ P APP A ++
Sbjct: 848 TKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAAT---APTPGI-PILQSVPSAPPPKAQSV 903
Query: 403 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 462
P+QAPP P S L P P A +++V + + P P V SPP S PV
Sbjct: 904 SPVQAPP-PGGSAQLLPGKVLVPLAAPSMSV---RGGGAGQPLPLV----SPPFSVPVQN 955
Query: 463 SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA---------------- 506
A PPS+ + P+ V PP+SP+ P P + P
Sbjct: 956 GAQPPSKI---IQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGG 1012
Query: 507 -APPLQLAKPPPQAPPALATPPLQAL--------PSPPASF-----PGQAPFSPSASLPM 552
A PL + QA + P ++ PS PA GQAP + +
Sbjct: 1013 HALPLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGV 1072
Query: 553 SPLATPPPQAPPVLAA---PLLQVPPSPPASPTLQAPRRPPTPGPD-------TSVSGPR 602
SP+ P PQ PP AA P++ S +PT AP P+ P TS + P
Sbjct: 1073 SPV--PSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPA 1130
Query: 603 LTLALAPGPPPPPSRSPSSTLSGPD-LAGHSSSATSTPEELRGYDSGP------------ 649
T+ L GPP P + +P+ T P AG + + P+ R P
Sbjct: 1131 ATI-LPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPV 1189
Query: 650 ---EGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLP------W--------- 691
E GA+ P P A P AP G P P P W
Sbjct: 1190 GSFEAGASGRPGP-APRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPP 1248
Query: 692 --PPATGPGSADG---LCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSR 746
PPA SA G + + + + + P G + G P A G SS
Sbjct: 1249 LPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSE 1308
Query: 747 SPKQARLGELP 757
S G+ P
Sbjct: 1309 SSSGRAAGDTP 1319
Score = 97.8 bits (242), Expect = 4e-20
Identities = 213/874 (24%), Positives = 300/874 (34%), Gaps = 186/874 (21%)
Query: 59 AERAGGIGGATIPESA-PRA-----------GPTRSAGTSSRNPASRPPASGRGERAPPA 106
AER +GG P SA PRA G S PAS G + P
Sbjct: 338 AERLHTVGG---PGSARPRAFSHSGVHSLDGGEVDSQALQELTQMVSGPASYSGPK-PST 393
Query: 107 KNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSAL---------- 156
+ +PGP ++PG G R S + A T +R +
Sbjct: 394 QYGAPGPFAAPGEGGALAATGRPPLLPTRASRSQRAASEDMTSDEERMVICEEEGDDDVI 453
Query: 157 ------------------SAGARRDTSGPTP----GTPSPAMARRSRAAGTEVGLP-RPA 193
+ D+SG P G + R++ T P P
Sbjct: 454 ADDGFGTTDIDLKCKERVTDSESGDSSGEDPEGNKGFGRKVFSPVIRSSFTHCRPPLDPE 513
Query: 194 PSARPRPPTEGPR--KSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL-- 249
P P PP + S S+S S S +A S G G + S+A PL
Sbjct: 514 PPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTAGPLRP 573
Query: 250 -----SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP------------------QVT 286
PA + R P PA + +P+ + L PP V
Sbjct: 574 PPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIAAPPSGGGNILQTLVL 633
Query: 287 PPRKDAAPALGPLSSSPLATPSPSAALQSQAPP-TLPATPHSSSLTCQL-ATPLPLAPPS 344
PP K+ G S P+PS A + A P + PA +++ + +TP+P+A S
Sbjct: 634 PPNKEEQEGGGARVPS---APAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTPVPIA--S 688
Query: 345 PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH---SFLPSPPLSPLATPPPQAPPALA 401
P S + SP T ++ GS + S + S S AT P AP +A
Sbjct: 689 KPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSP--APHLVA 746
Query: 402 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ-------------APFSPPPSPPV 448
P L PA+ + TP AP AV + A P+ PV
Sbjct: 747 GPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAGAGSGPNGPV 806
Query: 449 -----------------QAPFSPPASPPVSPSATPPSQAPPSLAAPP----------LQV 481
Q + P P A P+ AP + AA P +
Sbjct: 807 PLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTL 866
Query: 482 PPSPPASPPMSPSATPPPQAP----PPLAAPPLQLAKPPPQAPPALATPPLQALPSP--- 534
PP + + + P P P P A PP + P QAPP + Q LP
Sbjct: 867 PPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGS--AQLLPGKVLV 924
Query: 535 PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA----PLLQVPPSPPASPT-LQAPRRP 589
P + P + A P+ PL +PP P A ++Q+ P P ++P+ L P P
Sbjct: 925 PLAAPSMSVRGGGAGQPL-PLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSP 983
Query: 590 PT-PGPDTS------VSGPRLTL-------ALAPGPPPPPSRSPSSTLSGPDLA---GHS 632
T PGP + S R+T AL G P S++ + T GP + G +
Sbjct: 984 ATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPTSSVALGFT 1043
Query: 633 SSATSTP---EELRGYDSGP---EGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPG 686
S S P + L P G SP P +L PA + G AF
Sbjct: 1044 SLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLP---PACAAPGGPVITAFYSGSP 1100
Query: 687 APLPWPPATGPGSADG--LCTIYETEGPESAT------PAPGALDPGPS----PGTSGGK 734
AP P P A + T+ + P +AT PAP P P+ T+G
Sbjct: 1101 APTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSM 1160
Query: 735 AAAGAGAGASSRSPK-----QARLGELPLGALQA 763
+ A SPK +A + +P+G+ +A
Sbjct: 1161 TYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEA 1194
Score = 72.4 bits (176), Expect = 2e-12
Identities = 148/571 (25%), Positives = 196/571 (34%), Gaps = 114/571 (19%)
Query: 18 AARAPGLLTPRPPG-SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
A +AP LL P G SP P P + PA A G + G T SAP
Sbjct: 1059 AGQAP-LLAPGQVGVSPVPSPQLPPAC-------AAPGGPVITAFYSGSPAPT--SSAPL 1108
Query: 77 AGPTRSAGTSSRNPASR--PPASGRGERAPPAKNTS-PGPVSS-PGRASGTTRPGPLGQK 132
A P+++ + A+ PPA+ + PPA T+ P P S P +G+ + K
Sbjct: 1109 AQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPK 1168
Query: 133 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP-SPAMARRSRAAGTEV-GLP 190
R S + A + + AGA GP P P P R A +E+ G P
Sbjct: 1169 AQRPSPKAPQKVKAAIASIPVGSFEAGAS-GRPGPAPRQPLEPGPVREPTAPESELEGQP 1227
Query: 191 RP----------APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA-------GGG 233
P P+AR PP P + +SA P A + PS+ G G
Sbjct: 1228 TPPAPPPLPETWTPTARSSPPLPPPAEERTSAKG-----PETMASKFPSSSSDWRVPGQG 1282
Query: 234 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 293
L+ S P + A G S + RA + K + PP K
Sbjct: 1283 LENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEAAGTGKKVKVRPPPLKKTF 1342
Query: 294 PALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTC-------------QLATPLPL 340
++ S + A L P + +P SL + +T L
Sbjct: 1343 DSVDNRVLSEVDFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDS 1402
Query: 341 APPSPSAPPSLQ----TLPSPPATPPS---------------QATTSLGS--------PT 373
AP P++P + S P TP S +A LG +
Sbjct: 1403 APEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYDKVPYSS 1462
Query: 374 LQAT--------------HSFLPSPPLSPLATPPPQAPPALALPP---LQAPPSPPASPP 416
L+ T H F PS AT QA A P LQ
Sbjct: 1463 LRRTLDQRRALVMQLFQDHGFFPSAQ----ATAAFQARYADIFPSKVCLQLKIRE-VRQK 1517
Query: 417 LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ-APPSLA 475
+ ATP+ Q P A +AP PP A +P SP P T PS + + A
Sbjct: 1518 IMQAATPTEQPPGA------EAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQA 1571
Query: 476 APPLQVPPSPPASPPMSP--SATPPPQAPPP 504
APPL P PP S P P P P PPP
Sbjct: 1572 APPL---PPPPESGPGQPGWEGAPQPSPPPP 1599
Score = 67.0 bits (162), Expect = 7e-11
Identities = 164/700 (23%), Positives = 229/700 (32%), Gaps = 117/700 (16%)
Query: 16 TPAARAPGLLTPRPPGSPRPPPPVT-PAALRVL------GAAGAVGRKPLAERAGGIGG- 67
TP+ P L PG P V P++ R+ G A +G P + +AG +
Sbjct: 973 TPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSY 1032
Query: 68 ---ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGE---------RAPPAKNTSPGPVS 115
+++ GP+ A A + P G+ + PPA GPV
Sbjct: 1033 GPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVI 1092
Query: 116 SP--GRASGTTRPGPLGQKGLRI-SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP 172
+ + T PL Q S TVA +T P + L G P TP
Sbjct: 1093 TAFYSGSPAPTSSAPLAQPSQAPPSLVYTVAT--STTPPAATILPKGP----PAPATATP 1146
Query: 173 SPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG 232
+P S AG+ + AP A+ RP + P+K ++ + A RP
Sbjct: 1147 APTSPFPSATAGS-MTYSLVAPKAQ-RPSPKAPQKVKAAIASIPVGSFEAGASGRPG--- 1201
Query: 233 GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA 292
PA R P+ P G P PA P P+ A P + PP ++
Sbjct: 1202 ----PAPRQPLEPG-PVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEER 1256
Query: 293 APALGP------LSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPS 346
A GP SS P L+++ P P +P P P P S
Sbjct: 1257 TSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSP----------APAPAVAPGGS 1306
Query: 347 APPSLQTLPSPPATPPSQATTSLGS------PTLQATHSFLPSPPLSPLATPPPQAPPAL 400
+ S TP + G P L+ T + + LS +
Sbjct: 1307 SESSSGRAAGD--TPERKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEV-----DFEERF 1359
Query: 401 ALPPLQAPPSPPASPPLSPLATPSPQA-------PNALAVHLLQAPFSPPPSPPVQAPFS 453
A P P SP L LAT SP+A + L AP P S
Sbjct: 1360 AELPEFRPEEVLPSPTLQSLAT-SPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRS 1418
Query: 454 PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL---AAPPL 510
+S P +P + ++ + + + P L A +
Sbjct: 1419 SCSSEPNTPKS---AKCEGDIFTFDRTGTEAEDVLGELEYDKVPYSSLRRTLDQRRALVM 1475
Query: 511 QLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL--ATPPPQAPPVLAA 568
QL + P A AT QA + FP + + A P + PP A
Sbjct: 1476 QLFQDHGFFPSAQATAAFQARYAD--IFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEA 1533
Query: 569 PLLQVPPSPPASPTLQAPRRPPTP--GPD-TSVSGPRLTLALAPGPPPPPSRSPSSTLSG 625
PL P PP + T AP P+P GPD TS S T AP PPPP P
Sbjct: 1534 PL----PVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQP--- 1586
Query: 626 PDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA 665
G++ P+ + PPP AA
Sbjct: 1587 ------------------GWEGAPQ---PSPPPPGPSTAA 1605
Score = 65.5 bits (158), Expect = 2e-10
Identities = 103/382 (26%), Positives = 135/382 (35%), Gaps = 56/382 (14%)
Query: 445 SPPVQAPFS---PPASPPVSPSATPP-------SQAPPSLAAPPLQVPPSPPASPPMSPS 494
SP +++ F+ PP P PP AP S A+ P S S +
Sbjct: 496 SPVIRSSFTHCRPPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSG 555
Query: 495 ATPPPQAPPPLAAPPLQLAKPPPQAP-PALATPPLQALPSPPASFPGQAPFSPSASLPMS 553
++ A PL+ PPP A PA + + LP PA+F + P S P
Sbjct: 556 TFKAQESGQGSTAGPLR--PPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPG 613
Query: 554 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQA--PRRPPTPGPDTSVSGPRLTLALAPGP 611
P APP +LQ PP + R P P P +LA G
Sbjct: 614 PSVIA---APPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAP-----------SLAYGA 659
Query: 612 PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW 671
P P P++T+ + +STP + P G A + P D A
Sbjct: 660 PAAPLSRPAATM----VTNVVRPVSSTPVPIASKPF-PTSGRAEASPNDTAGARTEMGTG 714
Query: 672 SRGPA-PPLAF------RGAPGAPLPWPP-ATGP-----GSADGLCTIYETEGPESATPA 718
SR P PL + + A P P GP G A T P PA
Sbjct: 715 SRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPA 774
Query: 719 PGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGAL-------QASVVQHLLS 771
P A+ + G GG AG+GAGA S LG L GAL Q + L
Sbjct: 775 PPAVQ-FIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLP 833
Query: 772 RTLLLAAAEGAAGGS-GGGPGG 792
+ L +A A A G+ P G
Sbjct: 834 QQLQVAPAPAPAPGTKAAAPSG 855
Score = 56.6 bits (135), Expect = 9e-08
Identities = 100/432 (23%), Positives = 143/432 (33%), Gaps = 87/432 (20%)
Query: 9 KAGAAART-PAARAPGLLTPRP-----------PGSPRPP-PPVTPAALRVLGAAGAVGR 55
+AGA+ R PA R P L P P G P PP PP P +
Sbjct: 1193 EAGASGRPGPAPRQP--LEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLP 1250
Query: 56 KPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVS 115
P ER G T+ P S+ + R P RGE P + +P P
Sbjct: 1251 PPAEERTSAKGPETMASKFP------SSSSDWRVPGQG--LENRGE-PPTPPSPAPAPAV 1301
Query: 116 SPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG--------- 166
+PG +S ++ G R A T + K P + + R S
Sbjct: 1302 APGGSSESSSGRAAGDTPERKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERFAE 1361
Query: 167 -----PTPGTPSPAMARRSRAAGTEVGLPRPAPS------ARPRPPTEGPRKSVSSASEH 215
P PSP + + + +G R + P PT P++ + S
Sbjct: 1362 LPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPEDPTS-PKRKMRRRSSC 1420
Query: 216 STTEPSPAARRRPSAGGGLQRPASRS------LSSSATPLSSPARS-------------- 255
S+ +P + + R + + L P SS R+
Sbjct: 1421 SSEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQD 1480
Query: 256 ---GPSARGTPRAPAH-----PS---------QPKPKGLQALRPPQVTPPRKDAAPALGP 298
PSA+ T A PS + + K +QA P + P + P P
Sbjct: 1481 HGFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPP 1540
Query: 299 LSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPP 358
++ P+PS A P +P S S T Q A PLP P S P + P P
Sbjct: 1541 TGTAAAPAPTPSPAGGPD-----PTSPSSDSGTAQAAPPLPPPPESGPGQPGWEGAPQPS 1595
Query: 359 ATPPSQATTSLG 370
PP +T + G
Sbjct: 1596 PPPPGPSTAATG 1607
Score = 37.7 bits (86), Expect = 0.046
Identities = 41/139 (29%), Positives = 53/139 (38%), Gaps = 13/139 (9%)
Query: 428 PNALAV---HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS 484
P ++AV H L PF P P S P P A+ S+ P AA + PP
Sbjct: 29 PRSVAVFPWHSL-VPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPG 87
Query: 485 PPASP-PMSPSATPPPQAPPPLAAPPLQLAK----PPPQAPPALATPPLQ-ALPSPPASF 538
S P P P++P P PL + + PPP + PP + L S S
Sbjct: 88 GTGSADPERPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESD 147
Query: 539 PGQA---PFSPSASLPMSP 554
A SP LP+ P
Sbjct: 148 HDDAFLSIMSPEIQLPLPP 166
Score = 37.7 bits (86), Expect = 0.046
Identities = 41/147 (27%), Positives = 63/147 (42%), Gaps = 17/147 (11%)
Query: 358 PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP--SPPASP 415
P PSQ P++Q + + P P+A+ + P A + PP + A P
Sbjct: 42 PFLAPSQP-----DPSVQPSEA--QQPASHPVASNQSKEPAESAAVAHERPPGGTGSADP 94
Query: 416 PLSPLAT----PSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV-SPSATPPSQA 470
P AT P P P+ L V +++ PPP+ +A PP P + S + + A
Sbjct: 95 ERPPGATCPESPGPGPPHPLGV--VESGKGPPPTTEEEAS-GPPGEPRLDSETESDHDDA 151
Query: 471 PPSLAAPPLQVPPSPPASPPMSPSATP 497
S+ +P +Q+P P S SA P
Sbjct: 152 FLSIMSPEIQLPLPPGKRRTQSLSALP 178
Score = 36.2 bits (82), Expect = 0.13
Identities = 35/136 (25%), Positives = 46/136 (33%), Gaps = 34/136 (25%)
Query: 269 PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPP--------- 319
PSQP P P + PA P++S+ P+ SAA+ + PP
Sbjct: 46 PSQPDPS----------VQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPE 95
Query: 320 ----------TLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
P PH + P P S PP L S + A S+
Sbjct: 96 RPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHDDAFLSI 155
Query: 370 GSPTLQATHSFLPSPP 385
SP +Q LP PP
Sbjct: 156 MSPEIQ-----LPLPP 166
Score = 32.0 bits (71), Expect = 2.5
Identities = 38/156 (24%), Positives = 51/156 (32%), Gaps = 35/156 (22%)
Query: 191 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 250
+P PS +P + V+S E + A RP G G SA P
Sbjct: 48 QPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTG-----------SADPER 96
Query: 251 SPARSGPSARGTPRAPAHPSQPKPKGL--QALRPPQVT------PP---------RKDAA 293
P + P + G P P P G+ PP T PP D
Sbjct: 97 PPGATCPESPG-------PGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESDHD 149
Query: 294 PALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSS 329
A + S + P P ++Q+ LP SSS
Sbjct: 150 DAFLSIMSPEIQLPLPPGKRRTQSLSALPKERDSSS 185
Score = 30.8 bits (68), Expect = 5.6
Identities = 21/92 (22%), Positives = 27/92 (29%), Gaps = 7/92 (7%)
Query: 90 PASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE 149
P +PP + PP T+ P +P A G P G T
Sbjct: 1524 PTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSG-------TAQAAPPLP 1576
Query: 150 APKRSALSAGARRDTSGPTPGTPSPAMARRSR 181
P S P+P P P+ A R
Sbjct: 1577 PPPESGPGQPGWEGAPQPSPPPPGPSTAATGR 1608
Score = 30.4 bits (67), Expect = 7.3
Identities = 39/149 (26%), Positives = 51/149 (34%), Gaps = 24/149 (16%)
Query: 539 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT-PGPDTS 597
P AP P S+ P +A + P+ PA A RPP G
Sbjct: 42 PFLAPSQPDPSVQ-------PSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADP 94
Query: 598 VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASP 657
P T +PGP PP + GP +T EE SGP G P
Sbjct: 95 ERPPGATCPESPGPGPPHPLGVVESGKGP--------PPTTEEEA----SGPPG----EP 138
Query: 658 PPDAELAACHPAAWSRGPAPPLAFRGAPG 686
D+E + H A+ +P + PG
Sbjct: 139 RLDSETESDHDDAFLSIMSPEIQLPLPPG 167
>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
Length = 1003
Score = 141 bits (356), Expect = 2e-33
Identities = 230/836 (27%), Positives = 289/836 (34%), Gaps = 178/836 (21%)
Query: 35 PPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI--------PESAPRAG--PTRSAG 84
P PVTP V A+ K R + AT+ S+P G P
Sbjct: 78 PLAPVTPGGAGVGPASEEDMTKLCNHRRKAVAMATLYRSMETTCSHSSPGEGASPQMFHT 137
Query: 85 TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL--GQKGLRISAEETV 142
S P++RPP R PP + GP S P ++ P G GL
Sbjct: 138 VSPGPPSARPPC-----RVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGL-------F 185
Query: 143 ARGKATEAPKRSALSAGARRDTSGPTPGTPSP------------AMARRSRAAGTEVGLP 190
A P + S + P+P P P A RS +++G P
Sbjct: 186 PPRLADPVPSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSP 245
Query: 191 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 250
PAP A PP++ P + S+ T P P + P+ G +P S + +
Sbjct: 246 -PAPHASSSPPSDPP---LFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVL 301
Query: 251 SPARSGPSARGTPRAPA--------------HPSQPKPKGLQALRPPQVTPPRKDAAPAL 296
P P+ G P AP HP P P LQ RP + P + +L
Sbjct: 302 GPLGGAPTVEG-PGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRP-RAQAPSASHSSSL 359
Query: 297 GPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAP--PSLQTL 354
P P P+ L+ + P T P S P P + P PS P PS+ +L
Sbjct: 360 RPSQRRPRRPPTVFRLLEGRGPQT----PRRSRPRAPAPVPQPFSLPEPSQPILPSVLSL 415
Query: 355 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP-PQAPPALALP-----PLQAP 408
P PS + GS L + + LP PP +PP P+ P +LP L +
Sbjct: 416 LGLPTPGPSHSD---GSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSV 472
Query: 409 PSPPASP----------------------------PLSPLAT------PSPQAPNALA-- 432
P PA P PL PLA PSP+ AL+
Sbjct: 473 PGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGA 532
Query: 433 -----VHLLQAPFS---PPPSP----------------PVQAPFSPPASPPVSPSATPPS 468
+ L P S PPPSP P P PP P P A
Sbjct: 533 GFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEP 592
Query: 469 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP-LAAPPLQLAKPPPQAPPALATPP 527
+ P L A L PPS PPP APP L A L L P A +
Sbjct: 593 EGPSLLVASLLPPPPSDLL---------PPPSAPPSNLLASFLPLLALGPTAGDGEGS-- 641
Query: 528 LQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA---PLLQV---PPS--PPA 579
+ A P PFS L SPL PP APP L A LL PPS PP
Sbjct: 642 -----AEGAGGPSGEPFSGLGDL--SPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQ 694
Query: 580 SPTLQAPR-RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS---GPDLAGHSSSA 635
L AP+ PPT T+ + P A + G P S P LS G L G SS
Sbjct: 695 PCVLSAPQPGPPTSSVTTATTDPG---ASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSL 751
Query: 636 TSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT 695
TS+P L P G S +L G PPL+ +P A L
Sbjct: 752 TSSPGALPSLLQPP--GPLLSGQLGLQLLP------GGGAPPPLSEASSPLACLLQSLQI 803
Query: 696 GPGSADGLCTIYETEG----PESATPAPGAL-DPGPSPGTSGGKAAAGAGAGASSR 746
P + C E+ PE A P AL P SP + G G+G R
Sbjct: 804 PPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRGR 859
Score = 90.9 bits (224), Expect = 5e-18
Identities = 143/546 (26%), Positives = 178/546 (32%), Gaps = 124/546 (22%)
Query: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
P A AP P+P P P P+ P+ L +LG P
Sbjct: 389 PRAPAP---VPQPFSLPEPSQPILPSVLSLLG-------------------------LPT 420
Query: 77 AGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRI 136
GP+ S G+ + G PP S G P + PG
Sbjct: 421 PGPSHSDGSFN--------LLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPG--------- 463
Query: 137 SAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP-- 194
G + P A A ++ P PSP + S G G P P
Sbjct: 464 -----TTSGSLSSVPGAPAPPAASK------APVVPSPVLQSPSEGLGMGAGPACPLPPL 512
Query: 195 ---SARPRP-PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS-SSATPL 249
A P P P +G S + P P + +P L L+ P
Sbjct: 513 AGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPP 572
Query: 250 SSPARSGPSARGTPRAPAHPSQPK-------PKGLQALRPPQVTPPRKDAAP-----ALG 297
P P G P AP P P P L PP PP A ALG
Sbjct: 573 PEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALG 632
Query: 298 PLSS-----------------SPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPL 340
P + S L SP APPTL A +S+L P
Sbjct: 633 PTAGDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIAL--NSALLAATLDPPSG 690
Query: 341 APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP--LSPLATPPPQAPP 398
PP P + Q P PP + + ATT G+ +L S PP LSPL
Sbjct: 691 TPPQPCVLSAPQ--PGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLL-------G 741
Query: 399 ALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 458
A L L + S P + P S L P P L + LL +P P
Sbjct: 742 ASLLGDLSSLTSSPGALP-SLLQPPGPLLSGQLGLQLLPGGGAP---------------P 785
Query: 459 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP-SATPPPQAPPPLAAPPLQLAKPPP 517
P+S +++P + SL PP Q P P PP SP SA P A PPL+A P P
Sbjct: 786 PLSEASSPLACLLQSLQIPPEQ--PEAPCLPPESPASALEPEPARPPLSALAPPHGSPDP 843
Query: 518 QAPPAL 523
P L
Sbjct: 844 PVPELL 849
Score = 48.9 bits (115), Expect = 2e-05
Identities = 74/274 (27%), Positives = 99/274 (36%), Gaps = 58/274 (21%)
Query: 21 APGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG----GATIPESAPR 76
+PG L P +PP P+ L + G PL+E + + IP P
Sbjct: 754 SPGAL----PSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPE 809
Query: 77 AG--PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG-PVSSPGRASGTTRPGPLGQKG 133
A P S ++ +RPP S APP + P P GR SG + G G G
Sbjct: 810 APCLPPESPASALEPEPARPPLSAL---APPHGSPDPPVPELLTGRGSG--KRGRRGGGG 864
Query: 134 LR-ISAEETVARGK---ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189
LR I+ E ARG+ + P R AL G R +G +P + E G
Sbjct: 865 LRGINGEARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGGA 924
Query: 190 -----PRPAP--------------SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA 230
P P P S R R P ++ +S+ + T EPSP AR
Sbjct: 925 EPKDPPPPGPHSEDLKVPPGVVRKSRRGRRRKYNPTRNSNSSRQDITLEPSPTAR----- 979
Query: 231 GGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 264
+A PL AR G A+ R
Sbjct: 980 --------------AAVPLPPRARPGRPAKNKRR 999
Score = 32.0 bits (71), Expect = 2.5
Identities = 53/204 (25%), Positives = 75/204 (36%), Gaps = 25/204 (12%)
Query: 12 AAARTPAARAPGLLTPRPP-GSPRPPPP--VTPAALRVLGAAGAVGRKPLAERAGGIGGA 68
A+A P P L PP GSP PP P +T G G G + GI G
Sbjct: 819 ASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRGRRGGGGLR-------GINGE 871
Query: 69 TIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKN--TSPGPVSSPGRASGTTRP 126
P + G R G + +R +G+ ER+P + G ++ G + P
Sbjct: 872 ARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGG--AEPKDP 929
Query: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 186
P G + V R K+ +R + PSP +RAA
Sbjct: 930 PPPGPHSEDLKVPPGVVR-KSRRGRRRKYNPTRNSNSSRQDITLEPSPT----ARAA--- 981
Query: 187 VGLPRPAPSARPRPPTEGPRKSVS 210
V LP P ARP P + R+ ++
Sbjct: 982 VPLP---PRARPGRPAKNKRRKLA 1002
Score = 30.8 bits (68), Expect = 5.6
Identities = 38/149 (25%), Positives = 50/149 (33%), Gaps = 12/149 (8%)
Query: 607 LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD---SGPEGGAAASPPPDAEL 663
LAP P P+S L H A + R + S G ASP +
Sbjct: 79 LAPVTPGGAGVGPASEEDMTKLCNHRRKAVAMATLYRSMETTCSHSSPGEGASPQMFHTV 138
Query: 664 AACHPAAWSRGPAPPLA-FRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGAL 722
+ P+A PP G PG+ P PP+ GP P P
Sbjct: 139 SPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPT-------LAGPGGLFP-PRLA 190
Query: 723 DPGPSPGTSGGKAAAGAGAGASSRSPKQA 751
DP PS G+S + A + + P A
Sbjct: 191 DPVPSGGSSSPRFLPRGNAPSPAPPPPPA 219
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 140 bits (353), Expect = 5e-33
Identities = 175/619 (28%), Positives = 227/619 (36%), Gaps = 83/619 (13%)
Query: 75 PRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVS-SPGRASGTTRPGPLGQKG 133
P P S + A PP + + A+ PGP A P L
Sbjct: 548 PALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEADQHLLPPTLPTSA 607
Query: 134 LRISAEETVARGKATEA-----PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG 188
++++ T G+ + + ++ G+ D + PSPA S
Sbjct: 608 TSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAA------PSPAQCVCSPPVSEGPV 661
Query: 189 LPRPAPSARP-RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247
LP+ PS + PT P V S P+PA PS PA S +
Sbjct: 662 LPQSLPSLGAYQQPTAAPGLPVGSV-------PAPACP--PSLQQHFPDPAM-SFAPVLP 711
Query: 248 PLSSPARSGPSARGTPRAPAHPSQP--KPKGLQALRPPQVTPPRKDAAPALGPL--SSSP 303
P S+P +GP G P P P +P L + PQ P + P L P +S
Sbjct: 712 PPSTPMPTGP---GQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQ 768
Query: 304 LATPS-------PSAALQ--SQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTL 354
+ P+ P A LQ +Q PP +P P +T PL P A P L T
Sbjct: 769 VGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPIT-----PLAGIDGLPPALPDLPTA 823
Query: 355 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP--------PPQAPPALALPPLQ 406
PP PP + ++ P+L A P PP SP A P PP AP LA+P
Sbjct: 824 TVPPVPPPQYFSPAVILPSLAA-----PLPPASP-ALPLQAVKLPHPPGAP--LAMPCRT 875
Query: 407 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 466
P+ PA+ PL +A P A L++H A P P P P P SP T
Sbjct: 876 IVPNAPATIPLLAVAPPGVAA---LSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTV 932
Query: 467 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP 526
+ A PP P P PP P P P PP PP P P PP P
Sbjct: 933 QNMR----ATPPQPALPPQPTLPPQ-PVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLP 987
Query: 527 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP 586
P LP PA P P +P ATP Q +L P+P A A
Sbjct: 988 PQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQ--------ILLGHPAPYAVDV--AA 1037
Query: 587 RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS--TLSGPDLAGHSSSATSTPEELRG 644
+ P P P +V P L L P P + PSS T+S + + +AT P
Sbjct: 1038 QVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLLPPANPP 1097
Query: 645 YDSGPEGGAAASPPPDAEL 663
GP ASP P +L
Sbjct: 1098 LPGGP---GIASPCPTVQL 1113
Score = 102 bits (254), Expect = 2e-21
Identities = 159/617 (25%), Positives = 230/617 (37%), Gaps = 97/617 (15%)
Query: 31 GSPRPPPPVTPAALRVL------GAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84
G P PP P P A + L +A ++ + G + +S+ ++ S
Sbjct: 582 GQPGPPEPEEPEADQHLLPPTLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLA 641
Query: 85 TSSRNPAS---RPPASGRGERAP---PAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 138
++ +PA PP S G P P+ P ++PG G+ P P L+
Sbjct: 642 DAAPSPAQCVCSPPVS-EGPVLPQSLPSLGAYQQPTAAPGLPVGSV-PAPACPPSLQQHF 699
Query: 139 EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP 198
+ P + + G + PG P +A+ + +V P+P +P
Sbjct: 700 PDPAMSFAPVLPPPSTPMPTGPGQPAP---PGQQPPPLAQPTPLP--QVLAPQPVVPLQP 754
Query: 199 RPPTEGPRKSVSS---ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 255
PP P + +S A P A +P A Q P + TPL+
Sbjct: 755 VPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPI-PVVPPITPLAGIDGL 813
Query: 256 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS------P 309
P+ P A P P A+ P + P A+PAL PL + L P P
Sbjct: 814 PPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPAL-PLQAVKLPHPPGAPLAMP 872
Query: 310 SAALQSQAPPTLP----ATPHSSSLTCQLATP-LPLAPPSPSAPPSLQTLPSPPATPPSQ 364
+ AP T+P A P ++L+ A LP P P+A P + +P PPS
Sbjct: 873 CRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQM----APTDVPPSP 928
Query: 365 ATTSLGSPTLQATHSFLPSPPLSPLATPPPQA--PPALALPPLQAPPSPPASPPLSPLAT 422
T+Q + P P L P T PPQ PP LPP P P PP P+
Sbjct: 929 ------HHTVQNMRATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPP-QPVLP 981
Query: 423 PSPQAPNALAVHLLQAPFSPPPSPPVQA-PFSPPASPPVSPSATPPSQ------APPSL- 474
P P P Q P P+ PV+ P P +P+ATP SQ AP ++
Sbjct: 982 PQPMLPP-------QPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVD 1034
Query: 475 ---AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT--PPLQ 529
P + VPP+ SPP+ P AAP L PQ P +LAT +Q
Sbjct: 1035 VAAQVPTVPVPPAAVLSPPLPEVLLP--------AAPELL-----PQFPSSLATVSASVQ 1081
Query: 530 ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA--PLLQVPPSPPASPTLQAPR 587
++P+ A+ + P A PP P +A+ P +Q+ P +
Sbjct: 1082 SVPTQTAT--------------LLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDK 1127
Query: 588 RPPTPGPDTSVSGPRLT 604
P P S G +T
Sbjct: 1128 PPGLPQSCESYGGSDVT 1144
Score = 77.0 bits (188), Expect = 7e-14
Identities = 118/436 (27%), Positives = 154/436 (35%), Gaps = 94/436 (21%)
Query: 265 APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPAT 324
AP P P L +L PP+ + +D+AP LSS + S L SQA P+ P
Sbjct: 1323 APEAPESSPPLPLSSL-PPEAS---QDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPG 1378
Query: 325 PHSSSLTCQLATPLPLAPPSP--------SAPPSLQTLPSPPATPPSQATTSLGSPTLQA 376
A P PLAP SP A P+ T+P P + SQA G T Q
Sbjct: 1379 ----------APPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAG---GPGTPQG 1425
Query: 377 THSFLP-SPPLS-----PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNA 430
S L S PL+ PLA P A P +A + AS P PL P+P+
Sbjct: 1426 LTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEP--- 1482
Query: 431 LAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPP 490
+P S P P + P P+ P+A SLA L PP P PP
Sbjct: 1483 -------SPHSGTPQPALGQP------APLLPAAV----GAVSLATSQLPSPPLGPTVPP 1525
Query: 491 MSPSATPPP-QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP---GQAPFS- 545
PSA + PPP K + L S A P G F+
Sbjct: 1526 QPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTL 1585
Query: 546 -------PSASLPMSPLATPPPQAPPVLAAPLLQVP----PSPPASPTLQAPRRPPTPGP 594
P + + LA PP P + +Q+P +PT A T
Sbjct: 1586 EPLRGDQPRSEVCGGDLALPP--VPKEAVSGRVQLPQPLVEKSELAPTRGAVMEQGTSSS 1643
Query: 595 DTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY--------- 645
T+ S PR L G +A S S P+++ +
Sbjct: 1644 MTAESSPRSMLGY--------------DRDGRQVASDSHVVPSVPQDVPAFVRPARVEPT 1689
Query: 646 --DSGPEGGAAASPPP 659
D G G ++A PPP
Sbjct: 1690 DRDGGEAGESSAEPPP 1705
Score = 73.9 bits (180), Expect = 6e-13
Identities = 125/506 (24%), Positives = 170/506 (33%), Gaps = 96/506 (18%)
Query: 12 AAARTPAARAPGLLTPRPPGSP-----RPPPPVTPAAL-RVLGAAGAVGRKPLAERAGGI 65
A + P P P PG P +PPP P L +VL V +P+
Sbjct: 703 AMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPVP------ 756
Query: 66 GGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR 125
P P P G ++ + P + A P PV P
Sbjct: 757 -----PHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPP-------- 803
Query: 126 PGPL-GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184
PL G GL + + P + A + P P SPA+ ++
Sbjct: 804 ITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLP-PASPALPLQAVKLP 862
Query: 185 TEVGLP--RPAPSARPRPPTEGP-----RKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 237
G P P + P P P V++ S HS P P+
Sbjct: 863 HPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPA-------- 914
Query: 238 ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG 297
A ++ + P SP + + R TP PA P QP L P V PP+ P L
Sbjct: 915 AFPQMAPTDVP-PSPHHTVQNMRATPPQPALPPQP------TLPPQPVLPPQ----PTLP 963
Query: 298 PLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAP-------PS 350
P P+ P P+ Q P LP P + P P+ PP P+ P P
Sbjct: 964 P---QPVLPPQPTRPPQ----PVLPPQP--------MLPPQPVLPPQPALPVRPEPLQPH 1008
Query: 351 LQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPS 410
L +P ATP SQ +P + +P+ P+ P A P P L
Sbjct: 1009 LPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLPEVLL--------- 1059
Query: 411 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA 470
PA+P L PQ P++LA S P A PPA+PP+ S
Sbjct: 1060 -PAAPEL------LPQFPSSLAT----VSASVQSVPTQTATLLPPANPPLPGGPGIASPC 1108
Query: 471 PP-SLAAPPLQVPPSPPASPPMSPSA 495
P L P+Q + PP P +
Sbjct: 1109 PTVQLTVEPVQEEQASQDKPPGLPQS 1134
Score = 61.2 bits (147), Expect = 4e-09
Identities = 143/590 (24%), Positives = 191/590 (32%), Gaps = 146/590 (24%)
Query: 104 PPAKNTSP-GPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARR 162
P A++ +P P SSP P PL S + + + + + S L++
Sbjct: 1317 PVAEHPAPEAPESSP--------PLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLL 1368
Query: 163 DTSGPT--PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP-TEGPRKSVSSASEHSTTE 219
+GP+ PG P PAP A PP T P+ + A+ +T
Sbjct: 1369 SQAGPSNPPGAP-------------------PAPLAPSSPPVTALPQDGAAPAT---STM 1406
Query: 220 PSPAARRRPSAGGGLQRPASRSLSSSATPLS----SPARSGPSARGTPRAPAHPSQPKPK 275
P PA+ AGG S ++ PL+ +P P G P +
Sbjct: 1407 PEPASGTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTR 1466
Query: 276 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSL-TCQL 334
A R P + PP + +P G TP P+ Q P LPA + SL T QL
Sbjct: 1467 DASAPREP-LPPPAPEPSPHSG--------TPQPALG---QPAPLLPAAVGAVSLATSQL 1514
Query: 335 ATPLPLAPPSPSAPPS--------------------------LQTLPSPPATPPSQATTS 368
+P PL P P PPS L+TL P S A S
Sbjct: 1515 PSP-PLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSA--S 1571
Query: 369 LGSPTLQATHSFLPSPPLSPLATPPPQAPPA---LALPPLQAPPSPPASPPLSPLATPSP 425
G+P F L PL P++ LALPP+ PL S
Sbjct: 1572 AGTPVEVGDRDFT----LEPLRGDQPRSEVCGGDLALPPVPKEAVSGRVQLPQPLVEKSE 1627
Query: 426 QAPNALAV--HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS--QAPPSLAAPPLQV 481
AP AV + + SP + S S PS Q P+ P
Sbjct: 1628 LAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAFVRPARVE 1687
Query: 482 PPSPPASPPMSPSATPPPQA----------PPPLAAPPLQLAKPPPQ----APPA----- 522
P SA PPP P L A L + P+ + PA
Sbjct: 1688 PTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSSPAKTVGR 1747
Query: 523 -----------LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP------------- 558
LA+P +PP + +AP SP L + T
Sbjct: 1748 FSVVSTQDEWTLASPHSLRYSAPPDVYLDEAPSSPDVKLAVRRAQTASSIEVGVGEPVSS 1807
Query: 559 ------PPQAPPVLAAPLLQVPPS------PPASPTLQAPRRPPTPGPDT 596
P PPV L V S A+ LQ P R + GP+T
Sbjct: 1808 DSGDEGPRARPPVQKQASLPVSGSVAGDFVKKATAFLQRPSRAGSLGPET 1857
Score = 53.9 bits (128), Expect = 6e-07
Identities = 122/503 (24%), Positives = 162/503 (32%), Gaps = 125/503 (24%)
Query: 76 RAGPTRSAGT--SSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG 133
+AGP+ G + P+S P + + A PA +T P P S +G GP +G
Sbjct: 1370 QAGPSNPPGAPPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAG----GPGTPQG 1425
Query: 134 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 193
L E + + EAP + G P TP+P A A+ LP PA
Sbjct: 1426 LTSELETSQPLAETHEAP------LAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPA 1479
Query: 194 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253
P P T P + +P+P P+A G + SL++S P SP
Sbjct: 1480 PEPSPHSGTPQP----------ALGQPAPLL---PAAVGAV------SLATSQLP--SP- 1517
Query: 254 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL----------------G 297
P P P QP P L++ + PPR +
Sbjct: 1518 ---------PLGPTVPPQP-PSALES--DGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHV 1565
Query: 298 PLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSP 357
P SS+ TP P P S LA PP P S +
Sbjct: 1566 PTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLA-----LPPVPKEAVSGRVQLPQ 1620
Query: 358 PATPPSQATTSLGSPTLQATHSFL--PSPPLSPL---------------ATPPPQAPPAL 400
P S+ + G+ Q T S + S P S L PQ PA
Sbjct: 1621 PLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVPSVPQDVPAF 1680
Query: 401 ALPPLQAPP--------SPPASPPLSPLATPSPQA--PNALAVHLLQAPFSPPPSPPVQA 450
P P A PP S + T QA P L L +P P V +
Sbjct: 1681 VRPARVEPTDRDGGEAGESSAEPPPSDMGTVGGQASHPQTLGARALGSPRKRPEQQDVSS 1740
Query: 451 P------FSPPASPPVSPSATPPS---QAPPSLAAPPLQVPPSPP--------------- 486
P FS ++ A+P S APP + L PS P
Sbjct: 1741 PAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVY---LDEAPSSPDVKLAVRRAQTASSI 1797
Query: 487 ----ASPPMSPSATPPPQAPPPL 505
P S S P+A PP+
Sbjct: 1798 EVGVGEPVSSDSGDEGPRARPPV 1820
Score = 53.1 bits (126), Expect = 1e-06
Identities = 72/245 (29%), Positives = 95/245 (38%), Gaps = 39/245 (15%)
Query: 497 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 556
P P+AP ++PPL L+ PP+A A P L S Q F S L
Sbjct: 1322 PAPEAPE--SSPPLPLSSLPPEASQDSA-PYKDQLSSKE-----QPSFLASQQLLSQAGP 1373
Query: 557 TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 616
+ PP APP APL P SPP + Q P T SG T + A GP P
Sbjct: 1374 SNPPGAPP---APL--APSSPPVTALPQDGAAPATSTMPEPASG---TASQAGGPGTPQG 1425
Query: 617 RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPA 676
+ S P H + P + G A +P P+A A+ A+ R P
Sbjct: 1426 LTSELETSQPLAETHEAPLAVQPLVV--------GLAPCTPAPEA--ASTRDASAPREPL 1475
Query: 677 PPLAFRGAPGAPLPWP----PATGPGSADGLCTIYETE------GPESATPAPGALD--- 723
PP A +P + P P PA +A G ++ ++ GP P AL+
Sbjct: 1476 PPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDG 1535
Query: 724 PGPSP 728
GP P
Sbjct: 1536 EGPPP 1540
Score = 46.6 bits (109), Expect = 1e-04
Identities = 69/237 (29%), Positives = 89/237 (37%), Gaps = 46/237 (19%)
Query: 515 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 574
P P+AP + +PPL PP + AP+ S P Q L Q
Sbjct: 1322 PAPEAPES--SPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQL-------LSQAG 1372
Query: 575 PS-PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 633
PS PP +P AP P +P P T++ P+ A A P P+ +S GP +
Sbjct: 1373 PSNPPGAPP--APLAPSSP-PVTAL--PQDGAAPATSTMPEPASGTASQAGGPGTPQGLT 1427
Query: 634 SATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPP 693
S T + L P A P LA C PA A AP PLP PP
Sbjct: 1428 SELETSQPLAETHEAP----LAVQPLVVGLAPCTPAP----EAASTRDASAPREPLP-PP 1478
Query: 694 ATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGG--KAAAGAGAGASSRSP 748
A PE P+P + P P+ G AA GA + A+S+ P
Sbjct: 1479 A-----------------PE---PSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLP 1515
Score = 46.6 bits (109), Expect = 1e-04
Identities = 109/459 (23%), Positives = 158/459 (34%), Gaps = 85/459 (18%)
Query: 11 GAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERA-GGIGGAT 69
G A TPA A P P PPP P+ PL A G + AT
Sbjct: 1452 GLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLAT 1511
Query: 70 IPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129
+P GPT +PP++ ++ GP G T + L
Sbjct: 1512 SQLPSPPLGPT---------VPPQPPSA--------LESDGEGPPPRVGFVDSTIK--SL 1552
Query: 130 GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189
+K + +E V A+ + + G R T P G RS G ++ L
Sbjct: 1553 DEKLRTLLYQEHVPTSSASAG---TPVEVGDRDFTLEPLRGDQP-----RSEVCGGDLAL 1604
Query: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249
P P P + P+ V E S A P+ G +++ S S+++ ++P
Sbjct: 1605 P-PVPKEAVSGRVQLPQPLV---------EKSELA---PTRGAVMEQGTSSSMTAESSPR 1651
Query: 250 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 309
S + + PS P+ +RP +V P +D A G S+ P +
Sbjct: 1652 SMLGYDRDGRQVASDSHVVPSVPQDVP-AFVRPARVEPTDRDGGEA-GESSAEPPPSDMG 1709
Query: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
+ Q+ P TL A A SP P Q + SP T + S
Sbjct: 1710 TVGGQASHPQTLGAR----------------ALGSPRKRPEQQDVSSPAKTVGRFSVVST 1753
Query: 370 GSP-TLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP 428
TL + HS S APP + L +AP SP LA Q
Sbjct: 1754 QDEWTLASPHSLRYS------------APPDVYLD--EAPSSPDVK-----LAVRRAQTA 1794
Query: 429 NALAVHLLQAPFS------PPPSPPVQAPFSPPASPPVS 461
+++ V + + S P PPVQ S P S V+
Sbjct: 1795 SSIEVGVGEPVSSDSGDEGPRARPPVQKQASLPVSGSVA 1833
Score = 38.9 bits (89), Expect = 0.020
Identities = 40/157 (25%), Positives = 58/157 (36%), Gaps = 25/157 (15%)
Query: 222 PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR 281
P P G G PA A P + AR GP R R+ Q +P GL+A
Sbjct: 11 PGTLMEPGRGAG---PAGM-----AEPRAKAARPGPQ-RFLRRSVVESDQEEPPGLEAAE 61
Query: 282 PPQVTPPRKDAAPALGPLSSSPL---------ATPSPSAALQSQAPPTLPATPHSSSLTC 332
P PP+ L + L A P+P+A + P PA +
Sbjct: 62 APGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGT 121
Query: 333 QLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSL 369
Q P P+A +++T P+P P +A ++
Sbjct: 122 QEPGPDPIA-------AAVETAPAPDGGPREEAAATV 151
Score = 37.0 bits (84), Expect = 0.078
Identities = 40/154 (25%), Positives = 57/154 (37%), Gaps = 10/154 (6%)
Query: 249 LSSPAR-SGPSARGTPRAPAHPSQPKPKGL---QALRPPQVTPPRKDAAPALGPLSSSPL 304
L P R +GP+ PRA A ++P P+ + Q PP +AA A GP PL
Sbjct: 14 LMEPGRGAGPAGMAEPRAKA--ARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQPL 71
Query: 305 ATP----SPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPAT 360
+ L ++ PA P ++L Q P A P + + P P A
Sbjct: 72 QRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGPDPIAA 131
Query: 361 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP 394
A G P +A + + A P P
Sbjct: 132 AVETAPAPDGGPREEAAATVRKEDEGAAEAKPEP 165
Score = 36.6 bits (83), Expect = 0.10
Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 4/97 (4%)
Query: 489 PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 548
P + + P PQ P PL L L K P P+ + PG AP +P+
Sbjct: 55 PGLEAAEAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPG-APGAPAD 113
Query: 549 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 585
+ P P+ T P P+ AA ++ P+P P +A
Sbjct: 114 AGP-EPVGTQEPGPDPIAAA--VETAPAPDGGPREEA 147
Score = 32.3 bits (72), Expect = 1.9
Identities = 44/166 (26%), Positives = 51/166 (30%), Gaps = 18/166 (10%)
Query: 563 PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV------SGPRLTLALAPGPPPPPS 616
P L P P+ A P +A R P SV P L A APGP PP
Sbjct: 11 PGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQP 70
Query: 617 RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP--PDAELAACHPAAWSRG 674
L + E RG + P A + P P A A ++
Sbjct: 71 LQRRVLLL-------CKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQE 123
Query: 675 PAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG 720
P P AP P GP E EG A P PG
Sbjct: 124 PGPDPIAAAVETAP---APDGGPREEAAATVRKEDEGAAEAKPEPG 166
Score = 30.4 bits (67), Expect = 7.3
Identities = 39/155 (25%), Positives = 56/155 (36%), Gaps = 30/155 (19%)
Query: 111 PGPVSSPGRASG----------TTRPGPLGQKGLRISAEETVARG----KATEAP----- 151
PG + PGR +G RPGP Q+ LR S E+ +A EAP
Sbjct: 11 PGTLMEPGRGAGPAGMAEPRAKAARPGP--QRFLRRSVVESDQEEPPGLEAAEAPGPQPP 68
Query: 152 ----KRSALSAGARR---DTSGPTPGTPSPA-MARRSRAAGTEVGL-PRPAPSARPRPPT 202
+R L RR + + P P+PA + + A G P P + P P
Sbjct: 69 QPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGPDP 128
Query: 203 EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 237
+ A + E + A R+ G +P
Sbjct: 129 IAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKP 163
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 140 bits (353), Expect = 5e-33
Identities = 193/722 (26%), Positives = 268/722 (37%), Gaps = 100/722 (13%)
Query: 100 GERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEA---PKRSAL 156
G RAPP T P ++ PG G PL + IS + T A P +
Sbjct: 311 GTRAPPL--TRPMSLAVPGLTGGAGPAEPLSP-AMSISPQATYLSKLIPHAVLPPTVDVV 367
Query: 157 SAG--ARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 214
+ G + R S + + SPA R + G + P P +R P + S S +S+
Sbjct: 368 ALGRCSLRTLSRCSLHSASPASVR---SLGRFSSVSSPQPRSR-HPSSSSDTWSHSQSSD 423
Query: 215 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP--LSSPARSGPSARGTPRAPAHPS-- 270
++ S + S GG +P S + S+S P R PS T A S
Sbjct: 424 TIVSDGSTLS----SKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIR 479
Query: 271 -----QPKPKGLQALRPPQVTPPRKDAAPALG-PLSSSPLATPSPSAALQSQAPPTLPAT 324
+ L+ L+ P P R + G + PL P Q P LP
Sbjct: 480 SSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQ---PQLPRP 536
Query: 325 PHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSP 384
P + A P P P+ S P L P PP +L + ++ S P+
Sbjct: 537 PTTGGSEGAGAAPCP-PNPANSWVPGLS--PGGSRRPPRSPERTLSPSSGYSSQSGTPTL 593
Query: 385 PLSPLATPPPQAPPALALPP-------LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 437
P LA PP A P A PP L++P + +S S ++ S AP+ + +
Sbjct: 594 PPKGLAGPP--ASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQIL 651
Query: 438 AP----FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 493
P F PP P V APFSPP S P SP+ P+ A P++ P+ + P SPP
Sbjct: 652 TPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQ 711
Query: 494 SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS 553
+ P Q P ++ PPP PP+ PP PP P +PSA S
Sbjct: 712 TTLTPLQESPVISKD----QSPPPSPPPSYHPPP------PPTKKPEVVVEAPSA----S 757
Query: 554 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 613
A P Q P PP PP +P Q P P+ + ++A P
Sbjct: 758 ETAEEPLQDP--------NWPPPPPPAPEEQDLSMADFPPPEEAF------FSVASPEPA 803
Query: 614 PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR 673
PS SP +S P A SSSAT+ + G + PPP
Sbjct: 804 GPSGSP-ELVSSP--AASSSSATALQIQPPG---------SPDPPP-------------- 837
Query: 674 GPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGG 733
P P APG P G + G E G TP+ + S G GG
Sbjct: 838 APPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGG 897
Query: 734 KAAAGAGAGASSRSPKQARLGEL-PLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGG 792
G A + ++A G P+ A + + + + LAA+EG + GP
Sbjct: 898 APTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPE 957
Query: 793 AE 794
AE
Sbjct: 958 AE 959
Score = 110 bits (276), Expect = 4e-24
Identities = 190/714 (26%), Positives = 255/714 (35%), Gaps = 176/714 (24%)
Query: 36 PPPVTPAAL-----RVLGAAGAVGRKPLAERA-GGIGGATIPESAPRAGPTRSAGTSSRN 89
PP V AL R L P + R+ G + P+ R P+ S+ T S +
Sbjct: 361 PPTVDVVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRH-PSSSSDTWSHS 419
Query: 90 PASRPPAS--------GRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEET 141
+S S G E P + S V P SG R P G G A +T
Sbjct: 420 QSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSG--RGSPSG--GSTAEASDT 475
Query: 142 VARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT-EVGLPRPAPSAR--- 197
++ + + S S R+ P P + ++ +R A +GLP P P +
Sbjct: 476 LS---IRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLP-PKPERKQQP 531
Query: 198 --PRPPTEGPRKSVSSASEHSTTEPSPAARRRP--SAGGGLQRPAS--RSLSSSA---TP 248
PRPPT G + +A P+PA P S GG + P S R+LS S+ +
Sbjct: 532 QLPRPPTTGGSEGAGAAP----CPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQ 587
Query: 249 LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP---------QVTPPRKDAAPA---- 295
+P G P +P PKP+ + +LR P + D AP+
Sbjct: 588 SGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSG 647
Query: 296 ---LGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQ 352
L PL + P P PP+ P +P+ ++ LA P + P + S
Sbjct: 648 PQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPA--LAAPAVVPGPVSTTDAS-- 703
Query: 353 TLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP--------- 403
P P TP + T SP + S PSPP S PPP P + +
Sbjct: 704 --PQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAE 761
Query: 404 -PLQAPPSPPASPPL-------------------------------SPLATPSPQAPNAL 431
PLQ P PP PP SP SP A ++
Sbjct: 762 EPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSS 821
Query: 432 AVHL-LQAPFSP--PPSPPVQAPFSP--------PASPPV--SPSATPPSQ---AP---P 472
A L +Q P SP PP+PP AP S P PV S PP + AP P
Sbjct: 822 ATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTP 881
Query: 473 SL-------------AAPPLQVPPSPPASP---PMSPSATPPPQAPPPL-AAPPLQ---- 511
SL AP + PS P P +S A+P P L AA L+
Sbjct: 882 SLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSL 941
Query: 512 -----LAKPPPQAPPALATPPLQALPSPPASF---------PGQAPFSPSASLPM----- 552
L+ P PP P Q+ P+ ASF + P SP +
Sbjct: 942 AASEGLSSAQPNGPPEAEPRPPQS-PASTASFIFSKGSRKLQLERPVSPETQADLQRNLV 1000
Query: 553 ----SPLATPPPQAP--------PVLAAPLLQVPP-SPPASPTLQAPRRPPTPG 593
S PPQAP PV P + VPP + P+ P + PPT G
Sbjct: 1001 AELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNG 1054
Score = 94.4 bits (233), Expect = 4e-19
Identities = 165/638 (25%), Positives = 220/638 (34%), Gaps = 139/638 (21%)
Query: 13 AARTPAARAPGLLTPRPPGSPR----PPPPVTPAALRVLGAA---GAVGRKPLAERAGGI 65
A+ T + R+ G L+ R + PPPP +L G A G +G P ER
Sbjct: 472 ASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQ-- 529
Query: 66 GGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR 125
PR P + G+ A PP PA + PG SPG G+ R
Sbjct: 530 -----QPQLPR--PPTTGGSEGAGAAPCPPN--------PANSWVPG--LSPG---GSRR 569
Query: 126 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT 185
P ++ L S+ + G T PK A G P P + RS A
Sbjct: 570 PPRSPERTLSPSSGYSSQSGTPTLPPKGLA---GPPASPGKAQPPKPERVTSLRSPGASV 626
Query: 186 EVGLPR-------PAPSARPRPPTEGPRKSVSSASEHSTT----EPSPAARRRPSAGGGL 234
L PAPS R P P H P P+ R P+
Sbjct: 627 SSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPN----- 681
Query: 235 QRPASRSLSSSAT---PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKD 291
PA+ +L++ A P+S+ S P + TP+ P Q P + PP PP
Sbjct: 682 --PAAPALAAPAVVPGPVSTTDAS-PQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYH 738
Query: 292 AAPALGPLSSSPLATPSPSAALQSQAP-------PTLPATPHSSSLTCQLATP-----LP 339
P P + +PSA+ ++ P P P P L+ P
Sbjct: 739 PPPP--PTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFS 796
Query: 340 LAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA-TPPPQAPP 398
+A P P+ P L S PA S AT LQ P PP +P A P AP
Sbjct: 797 VASPEPAGPSGSPELVSSPAASSSSATA------LQIQPPGSPDPPPAPPAPAPASSAPG 850
Query: 399 ALALPPLQAPPS------PPASPPLSPLATPSPQAPNALAVHLLQAPFSPP--------P 444
+A P + P PP +PL TPS + + + AP P P
Sbjct: 851 HVAKLPQKEPVGCSKGGGPPREDVGAPLVTPS--LLQMVRLRSVGAPGGAPTPALGPSAP 908
Query: 445 SPPVQAPFSPPASPPVSPSATPPSQ---------APPSLAAPPLQVPPSPPASPPMSPSA 495
P++ S ASP +PS+ + A L++ PP PP SP++
Sbjct: 909 QKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPAS 968
Query: 496 TPP--------------PQAPPPLA---------------APPLQLAKPPPQAPPALATP 526
T P +P A P Q K P+APP +A
Sbjct: 969 TASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARK 1028
Query: 527 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 564
P +P PPAS P P A PL PP P
Sbjct: 1029 PSVGVP-PPAS-----PSYPRA----EPLTAPPTNGLP 1056
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 138 bits (348), Expect = 2e-32
Identities = 177/638 (27%), Positives = 247/638 (38%), Gaps = 97/638 (15%)
Query: 56 KPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVS 115
KP+ E G+ G + + R +R + ++ R+ + PAS G +P ++ +
Sbjct: 3 KPVKEEDDGLSG----KHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRN 58
Query: 116 SPGRASGTTRPGPLG--QKGLRISAEETVARGKA-----------TEAPKRSALSAGARR 162
SP AS ++ +K + EE + K+ TE R++ +
Sbjct: 59 SPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQ 118
Query: 163 DTSGPTPGTPSPAMARRSRAAGTEVG-----LPRPAPSARPRPPTEGPRKSVS-SASEHS 216
+ S P + + SR+ E + + S P P+ +S S S+++
Sbjct: 119 EISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQ 178
Query: 217 TTEPSPAARRRP--------SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 268
+ P A + P SA G + + + SAT + P + P+A P P
Sbjct: 179 MLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAV--PPQGSPTASQAPNQPQA 236
Query: 269 PSQPKPK-------GLQALRPPQV-TPPRKDAAPALGPLSSSPLATPSPSAA---LQSQA 317
P+ P P L RPP PP P L PL+ S +PS A L Q
Sbjct: 237 PTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 296
Query: 318 PPTLPATPHSSSLTCQLATPLPLAPPSP-SAPPSLQTLPSPPATPPSQAT--TSLGSPTL 374
PP PHS L P PP P PP +P T P+ A TSL P
Sbjct: 297 PPG----PHSLQAGPLLQHP---GPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 349
Query: 375 QATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 434
Q+ P PL P AP LA+P ++ PP+ P P L P+PQA
Sbjct: 350 QSALQSQQPPREQPL----PPAP--LAMPHIKPPPTTPI-PQL-----PAPQAHKHPPHL 397
Query: 435 LLQAPFSPPPSPPVQAPFSPPASPPVSPSAT--PPSQAPPSLAAPPLQVP-PSPPASPP- 490
+PFS + P PPA P+S +T PPS PP L P P PS PA PP
Sbjct: 398 SGPSPFSMNANLP-----PPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPG 452
Query: 491 MSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL 550
++ S P PPP + PP L + PQ P A Q PF P
Sbjct: 453 LTQSQNLP---PPPASHPPTGLHQVAPQPPFA------------------QHPFVPGGPP 491
Query: 551 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 610
P++P P PP Q P S A+ P P + L A P
Sbjct: 492 PITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPE 551
Query: 611 PPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL-RGYDS 647
PPPP RSPS + D H+S + + L RGY+S
Sbjct: 552 SPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNS 589
Score = 117 bits (292), Expect = 6e-26
Identities = 139/531 (26%), Positives = 196/531 (36%), Gaps = 99/531 (18%)
Query: 70 IPESAPRAGPTRSAGTSSRNPASRP--PASGRGERAPPAK-----NTSPGPVSSPGRASG 122
+ A T S T ++ SRP P+ G GE + ++ P + R++
Sbjct: 100 VASDTEEADRTSSKKTKTQE-ISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTS 158
Query: 123 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 182
+ P P + S ++ A+ + +A + AL A PT TP+P+ A
Sbjct: 159 PSIPSPQDNE----SDSDSSAQQQMLQA-QPPALQA--------PTGVTPAPSSA----P 201
Query: 183 AGT-EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 241
GT ++ P P PSA PP P S + + T P P + + QRP S
Sbjct: 202 PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH 261
Query: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPK----PKGLQALR---------PPQVTPP 288
+P P + + G P AP+H P P G +L+ PPQ
Sbjct: 262 PPPHPSP-HPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGL 320
Query: 289 RKDAAPALGPLSSSPLAT--------PSPSAALQSQAPPTLPATPHSSSLTCQLATPLPL 340
A+ PL +SP A P+ +ALQSQ PP P P PL
Sbjct: 321 PPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP-----------PAPL 369
Query: 341 APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP-LSPLATPPPQAPPA 399
A P PP+ +P PA + L P+ + ++ LP PP L PL++ PP+
Sbjct: 370 AMPHIKPPPTTP-IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPS 428
Query: 400 LALPPLQAPPSP---PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP-VQAPFSPP 455
PPLQ P P+SP P T S P A H P PP Q PF P
Sbjct: 429 AHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPG 488
Query: 456 ASPPVSPSATPPSQAPP-------------------------SLAAPPLQVP-------- 482
PP++P P + PP S P +Q+
Sbjct: 489 GPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAE 548
Query: 483 -PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP 532
P P PP SPS P P A+ + K + + A L +P
Sbjct: 549 EPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMP 599
Score = 115 bits (288), Expect = 2e-25
Identities = 156/555 (28%), Positives = 211/555 (38%), Gaps = 98/555 (17%)
Query: 225 RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ 284
+++P++ G P + + SS R+ PSA T + K K + ++
Sbjct: 35 KKQPASPDGRTSPINEDIRSSG-------RNSPSAASTSSNDSKAETVK-KSAKKVKEEA 86
Query: 285 VTPPRKDAAPALGPLSSSPLA--TPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAP 342
+P + + S + A T S Q + P P+ S + +
Sbjct: 87 SSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSD 146
Query: 343 PSPSAPPSLQTLPSPPATPP--SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 400
P + T PS P+ S + +S LQA L +P + + P APP
Sbjct: 147 PKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAP--TGVTPAPSSAPPGT 204
Query: 401 ALPPLQAP-PSPPASPPL-SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 458
P P PS A PP SP A+ +P P QAP +P P +Q +P P
Sbjct: 205 PQLPTPGPTPSATAVPPQGSPTASQAPNQP--------QAPTAPVPHTHIQQ--APALHP 254
Query: 459 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP---QAPPPLAAPPLQLAKP 515
PS PP P PPLQ P + A P +PS PP Q PP P L
Sbjct: 255 QRPPSPHPPPHPSPH---PPLQ-PLTGSAGQPSAPSHAQPPLHGQGPPG----PHSL--- 303
Query: 516 PPQAPPALATP-PLQALPSPPASFPGQAPF--SPSASLPMSPLATP----------PPQA 562
QA P L P P Q PP + GQAP SP+A+ P + L P PP+
Sbjct: 304 --QAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPRE 361
Query: 563 PPVLAAPL----LQVPPSPPAS--PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 616
P+ APL ++ PP+ P P QA + PP +SGP ++ PPPP+
Sbjct: 362 QPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPP------HLSGPS-PFSMNANLPPPPA 414
Query: 617 RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELA------ACHPAA 670
P S+LS H SA P +L S P + A PP + A HP
Sbjct: 415 LKPLSSLS----THHPPSAHPPPLQLMP-QSQPLPSSPAQPPGLTQSQNLPPPPASHPPT 469
Query: 671 WSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGT 730
AP F P P PP T P P ++TP G PGT
Sbjct: 470 GLHQVAPQPPFAQHPFVPGGPPPITPPTC------------PSTSTPPAG-------PGT 510
Query: 731 SGGKAAAGAGAGASS 745
S +GA A S
Sbjct: 511 SAQPPCSGAAASGGS 525
Score = 93.2 bits (230), Expect = 9e-19
Identities = 127/480 (26%), Positives = 166/480 (34%), Gaps = 104/480 (21%)
Query: 14 ARTPAARAPGLLTP----RPPGSPR-PPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68
A+ PA +AP +TP PPG+P+ P P TP+A V
Sbjct: 182 AQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAV---------------------- 219
Query: 69 TIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAP---PAKNTSPGPVSSPGRASGTTR 125
P+ PT S + + P ++AP P + SP P P
Sbjct: 220 -----PPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS------- 267
Query: 126 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT---PGTPSPAMARRSRA 182
P P Q L SA + A A + P G +GP PG P P
Sbjct: 268 PHPPLQP-LTGSAGQPSAPSHA-QPPLHGQGPPGPHSLQAGPLLQHPGPPQP-------- 317
Query: 183 AGTEVGLPRPAPSAR----PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA 238
GLP A + P P S+ + S + R +P PA
Sbjct: 318 ----FGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP------PA 367
Query: 239 SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP 298
++ P ++P P+ + + P H S P P + A PP PAL P
Sbjct: 368 PLAMPHIKPPPTTPIPQLPAPQ-AHKHPPHLSGPSPFSMNANLPP---------PPALKP 417
Query: 299 LSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPP 358
LSS L+T P +A PP L P S PLP +P P Q LP PP
Sbjct: 418 LSS--LSTHHPPSA----HPPPLQLMPQSQ--------PLPSSPAQPPGLTQSQNLPPPP 463
Query: 359 ATPPSQATTSLGSPTLQATHSFLPS--PPLSPLATPPPQAPPALALPPLQAPPSPPASPP 416
A+ P + A H F+P PP++P P PP A P A PP
Sbjct: 464 ASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPP--------AGPGTSAQPP 515
Query: 417 LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 476
S A + L + P SPP PP SPS P PS A+
Sbjct: 516 CSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP-PPPRSPSPEPTVVDTPSHAS 574
Score = 43.9 bits (102), Expect = 6e-04
Identities = 69/257 (26%), Positives = 90/257 (35%), Gaps = 69/257 (26%)
Query: 532 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPP-VLAAPLLQVPPSPPASPTLQAPRRPP 590
PS P+ ++ SA M P QAP V AP +PP +P L P
Sbjct: 159 PSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP----SSAPPGTPQL------P 208
Query: 591 TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE 650
TPGP S + A+ P P S++P+ + H+ + P+
Sbjct: 209 TPGPTPSAT------AVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH-------PQ 255
Query: 651 GGAAASPPPDAELAACHPAAWSRGPAPPL----AFRGAPGAPL-PWPPATGPGSADGLCT 705
+ PPP HP+ P PPL G P AP PP G G
Sbjct: 256 RPPSPHPPP-------HPS-----PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP----- 298
Query: 706 IYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASV 765
GP S P PGP P G P QA G+ PLG A+
Sbjct: 299 -----GPHSLQAGPLLQHPGP-PQPFG--------------LPPQASQGQAPLGTSPAAA 338
Query: 766 VQHLLSRTLLLAAAEGA 782
H +L L A++ A
Sbjct: 339 YPH---TSLQLPASQSA 352
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 138 bits (348), Expect = 2e-32
Identities = 177/638 (27%), Positives = 247/638 (38%), Gaps = 97/638 (15%)
Query: 56 KPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVS 115
KP+ E G+ G + + R +R + ++ R+ + PAS G +P ++ +
Sbjct: 557 KPVKEEDDGLSG----KHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRN 612
Query: 116 SPGRASGTTRPGPLG--QKGLRISAEETVARGKA-----------TEAPKRSALSAGARR 162
SP AS ++ +K + EE + K+ TE R++ +
Sbjct: 613 SPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQ 672
Query: 163 DTSGPTPGTPSPAMARRSRAAGTEVG-----LPRPAPSARPRPPTEGPRKSVS-SASEHS 216
+ S P + + SR+ E + + S P P+ +S S S+++
Sbjct: 673 EISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQ 732
Query: 217 TTEPSPAARRRP--------SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 268
+ P A + P SA G + + + SAT + P + P+A P P
Sbjct: 733 MLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAV--PPQGSPTASQAPNQPQA 790
Query: 269 PSQPKPK-------GLQALRPPQV-TPPRKDAAPALGPLSSSPLATPSPSAA---LQSQA 317
P+ P P L RPP PP P L PL+ S +PS A L Q
Sbjct: 791 PTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 850
Query: 318 PPTLPATPHSSSLTCQLATPLPLAPPSP-SAPPSLQTLPSPPATPPSQAT--TSLGSPTL 374
PP PHS L P PP P PP +P T P+ A TSL P
Sbjct: 851 PPG----PHSLQAGPLLQHP---GPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 903
Query: 375 QATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 434
Q+ P PL P AP LA+P ++ PP+ P P L P+PQA
Sbjct: 904 QSALQSQQPPREQPL----PPAP--LAMPHIKPPPTTPI-PQL-----PAPQAHKHPPHL 951
Query: 435 LLQAPFSPPPSPPVQAPFSPPASPPVSPSAT--PPSQAPPSLAAPPLQVP-PSPPASPP- 490
+PFS + P PPA P+S +T PPS PP L P P PS PA PP
Sbjct: 952 SGPSPFSMNANLP-----PPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPG 1006
Query: 491 MSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL 550
++ S P PPP + PP L + PQ P A Q PF P
Sbjct: 1007 LTQSQNLP---PPPASHPPTGLHQVAPQPPFA------------------QHPFVPGGPP 1045
Query: 551 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 610
P++P P PP Q P S A+ P P + L A P
Sbjct: 1046 PITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPE 1105
Query: 611 PPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL-RGYDS 647
PPPP RSPS + D H+S + + L RGY+S
Sbjct: 1106 SPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNS 1143
Score = 117 bits (292), Expect = 6e-26
Identities = 139/531 (26%), Positives = 196/531 (36%), Gaps = 99/531 (18%)
Query: 70 IPESAPRAGPTRSAGTSSRNPASRP--PASGRGERAPPAK-----NTSPGPVSSPGRASG 122
+ A T S T ++ SRP P+ G GE + ++ P + R++
Sbjct: 654 VASDTEEADRTSSKKTKTQE-ISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTS 712
Query: 123 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 182
+ P P + S ++ A+ + +A + AL A PT TP+P+ A
Sbjct: 713 PSIPSPQDNE----SDSDSSAQQQMLQA-QPPALQA--------PTGVTPAPSSA----P 755
Query: 183 AGT-EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 241
GT ++ P P PSA PP P S + + T P P + + QRP S
Sbjct: 756 PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH 815
Query: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPK----PKGLQALR---------PPQVTPP 288
+P P + + G P AP+H P P G +L+ PPQ
Sbjct: 816 PPPHPSP-HPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGL 874
Query: 289 RKDAAPALGPLSSSPLAT--------PSPSAALQSQAPPTLPATPHSSSLTCQLATPLPL 340
A+ PL +SP A P+ +ALQSQ PP P P PL
Sbjct: 875 PPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP-----------PAPL 923
Query: 341 APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP-LSPLATPPPQAPPA 399
A P PP+ +P PA + L P+ + ++ LP PP L PL++ PP+
Sbjct: 924 AMPHIKPPPTTP-IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPS 982
Query: 400 LALPPLQAPPSP---PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP-VQAPFSPP 455
PPLQ P P+SP P T S P A H P PP Q PF P
Sbjct: 983 AHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPG 1042
Query: 456 ASPPVSPSATPPSQAPP-------------------------SLAAPPLQVP-------- 482
PP++P P + PP S P +Q+
Sbjct: 1043 GPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAE 1102
Query: 483 -PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP 532
P P PP SPS P P A+ + K + + A L +P
Sbjct: 1103 EPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMP 1153
Score = 115 bits (288), Expect = 2e-25
Identities = 156/555 (28%), Positives = 211/555 (38%), Gaps = 98/555 (17%)
Query: 225 RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ 284
+++P++ G P + + SS R+ PSA T + K K + ++
Sbjct: 589 KKQPASPDGRTSPINEDIRSSG-------RNSPSAASTSSNDSKAETVK-KSAKKVKEEA 640
Query: 285 VTPPRKDAAPALGPLSSSPLA--TPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAP 342
+P + + S + A T S Q + P P+ S + +
Sbjct: 641 SSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSD 700
Query: 343 PSPSAPPSLQTLPSPPATPP--SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 400
P + T PS P+ S + +S LQA L +P + + P APP
Sbjct: 701 PKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAP--TGVTPAPSSAPPGT 758
Query: 401 ALPPLQAP-PSPPASPPL-SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 458
P P PS A PP SP A+ +P P QAP +P P +Q +P P
Sbjct: 759 PQLPTPGPTPSATAVPPQGSPTASQAPNQP--------QAPTAPVPHTHIQQ--APALHP 808
Query: 459 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP---QAPPPLAAPPLQLAKP 515
PS PP P PPLQ P + A P +PS PP Q PP P L
Sbjct: 809 QRPPSPHPPPHPSPH---PPLQ-PLTGSAGQPSAPSHAQPPLHGQGPPG----PHSL--- 857
Query: 516 PPQAPPALATP-PLQALPSPPASFPGQAPF--SPSASLPMSPLATP----------PPQA 562
QA P L P P Q PP + GQAP SP+A+ P + L P PP+
Sbjct: 858 --QAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPRE 915
Query: 563 PPVLAAPL----LQVPPSPPAS--PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 616
P+ APL ++ PP+ P P QA + PP +SGP ++ PPPP+
Sbjct: 916 QPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPP------HLSGPS-PFSMNANLPPPPA 968
Query: 617 RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELA------ACHPAA 670
P S+LS H SA P +L S P + A PP + A HP
Sbjct: 969 LKPLSSLS----THHPPSAHPPPLQLMP-QSQPLPSSPAQPPGLTQSQNLPPPPASHPPT 1023
Query: 671 WSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGT 730
AP F P P PP T P P ++TP G PGT
Sbjct: 1024 GLHQVAPQPPFAQHPFVPGGPPPITPPTC------------PSTSTPPAG-------PGT 1064
Query: 731 SGGKAAAGAGAGASS 745
S +GA A S
Sbjct: 1065 SAQPPCSGAAASGGS 1079
Score = 93.2 bits (230), Expect = 9e-19
Identities = 127/480 (26%), Positives = 166/480 (34%), Gaps = 104/480 (21%)
Query: 14 ARTPAARAPGLLTP----RPPGSPR-PPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68
A+ PA +AP +TP PPG+P+ P P TP+A V
Sbjct: 736 AQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAV---------------------- 773
Query: 69 TIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAP---PAKNTSPGPVSSPGRASGTTR 125
P+ PT S + + P ++AP P + SP P P
Sbjct: 774 -----PPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS------- 821
Query: 126 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT---PGTPSPAMARRSRA 182
P P Q L SA + A A + P G +GP PG P P
Sbjct: 822 PHPPLQP-LTGSAGQPSAPSHA-QPPLHGQGPPGPHSLQAGPLLQHPGPPQP-------- 871
Query: 183 AGTEVGLPRPAPSAR----PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA 238
GLP A + P P S+ + S + R +P PA
Sbjct: 872 ----FGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP------PA 921
Query: 239 SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP 298
++ P ++P P+ + + P H S P P + A PP PAL P
Sbjct: 922 PLAMPHIKPPPTTPIPQLPAPQ-AHKHPPHLSGPSPFSMNANLPP---------PPALKP 971
Query: 299 LSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPP 358
LSS L+T P +A PP L P S PLP +P P Q LP PP
Sbjct: 972 LSS--LSTHHPPSA----HPPPLQLMPQSQ--------PLPSSPAQPPGLTQSQNLPPPP 1017
Query: 359 ATPPSQATTSLGSPTLQATHSFLPS--PPLSPLATPPPQAPPALALPPLQAPPSPPASPP 416
A+ P + A H F+P PP++P P PP A P A PP
Sbjct: 1018 ASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPP--------AGPGTSAQPP 1069
Query: 417 LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 476
S A + L + P SPP PP SPS P PS A+
Sbjct: 1070 CSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP-PPPRSPSPEPTVVDTPSHAS 1128
Score = 43.9 bits (102), Expect = 6e-04
Identities = 69/257 (26%), Positives = 90/257 (35%), Gaps = 69/257 (26%)
Query: 532 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPP-VLAAPLLQVPPSPPASPTLQAPRRPP 590
PS P+ ++ SA M P QAP V AP +PP +P L P
Sbjct: 713 PSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP----SSAPPGTPQL------P 762
Query: 591 TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE 650
TPGP S + A+ P P S++P+ + H+ + P+
Sbjct: 763 TPGPTPSAT------AVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH-------PQ 809
Query: 651 GGAAASPPPDAELAACHPAAWSRGPAPPL----AFRGAPGAPL-PWPPATGPGSADGLCT 705
+ PPP HP+ P PPL G P AP PP G G
Sbjct: 810 RPPSPHPPP-------HPS-----PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP----- 852
Query: 706 IYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASV 765
GP S P PGP P G P QA G+ PLG A+
Sbjct: 853 -----GPHSLQAGPLLQHPGP-PQPFG--------------LPPQASQGQAPLGTSPAAA 892
Query: 766 VQHLLSRTLLLAAAEGA 782
H +L L A++ A
Sbjct: 893 YPH---TSLQLPASQSA 906
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 138 bits (348), Expect = 2e-32
Identities = 177/638 (27%), Positives = 247/638 (38%), Gaps = 97/638 (15%)
Query: 56 KPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVS 115
KP+ E G+ G + + R +R + ++ R+ + PAS G +P ++ +
Sbjct: 557 KPVKEEDDGLSG----KHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRN 612
Query: 116 SPGRASGTTRPGPLG--QKGLRISAEETVARGKA-----------TEAPKRSALSAGARR 162
SP AS ++ +K + EE + K+ TE R++ +
Sbjct: 613 SPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQ 672
Query: 163 DTSGPTPGTPSPAMARRSRAAGTEVG-----LPRPAPSARPRPPTEGPRKSVS-SASEHS 216
+ S P + + SR+ E + + S P P+ +S S S+++
Sbjct: 673 EISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQ 732
Query: 217 TTEPSPAARRRP--------SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 268
+ P A + P SA G + + + SAT + P + P+A P P
Sbjct: 733 MLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAV--PPQGSPTASQAPNQPQA 790
Query: 269 PSQPKPK-------GLQALRPPQV-TPPRKDAAPALGPLSSSPLATPSPSAA---LQSQA 317
P+ P P L RPP PP P L PL+ S +PS A L Q
Sbjct: 791 PTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG 850
Query: 318 PPTLPATPHSSSLTCQLATPLPLAPPSP-SAPPSLQTLPSPPATPPSQAT--TSLGSPTL 374
PP PHS L P PP P PP +P T P+ A TSL P
Sbjct: 851 PPG----PHSLQAGPLLQHP---GPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS 903
Query: 375 QATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 434
Q+ P PL P AP LA+P ++ PP+ P P L P+PQA
Sbjct: 904 QSALQSQQPPREQPL----PPAP--LAMPHIKPPPTTPI-PQL-----PAPQAHKHPPHL 951
Query: 435 LLQAPFSPPPSPPVQAPFSPPASPPVSPSAT--PPSQAPPSLAAPPLQVP-PSPPASPP- 490
+PFS + P PPA P+S +T PPS PP L P P PS PA PP
Sbjct: 952 SGPSPFSMNANLP-----PPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPG 1006
Query: 491 MSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL 550
++ S P PPP + PP L + PQ P A Q PF P
Sbjct: 1007 LTQSQNLP---PPPASHPPTGLHQVAPQPPFA------------------QHPFVPGGPP 1045
Query: 551 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 610
P++P P PP Q P S A+ P P + L A P
Sbjct: 1046 PITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPE 1105
Query: 611 PPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL-RGYDS 647
PPPP RSPS + D H+S + + L RGY+S
Sbjct: 1106 SPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNS 1143
Score = 117 bits (292), Expect = 6e-26
Identities = 139/531 (26%), Positives = 196/531 (36%), Gaps = 99/531 (18%)
Query: 70 IPESAPRAGPTRSAGTSSRNPASRP--PASGRGERAPPAK-----NTSPGPVSSPGRASG 122
+ A T S T ++ SRP P+ G GE + ++ P + R++
Sbjct: 654 VASDTEEADRTSSKKTKTQE-ISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTS 712
Query: 123 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 182
+ P P + S ++ A+ + +A + AL A PT TP+P+ A
Sbjct: 713 PSIPSPQDNE----SDSDSSAQQQMLQA-QPPALQA--------PTGVTPAPSSA----P 755
Query: 183 AGT-EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 241
GT ++ P P PSA PP P S + + T P P + + QRP S
Sbjct: 756 PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH 815
Query: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPK----PKGLQALR---------PPQVTPP 288
+P P + + G P AP+H P P G +L+ PPQ
Sbjct: 816 PPPHPSP-HPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGL 874
Query: 289 RKDAAPALGPLSSSPLAT--------PSPSAALQSQAPPTLPATPHSSSLTCQLATPLPL 340
A+ PL +SP A P+ +ALQSQ PP P P PL
Sbjct: 875 PPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP-----------PAPL 923
Query: 341 APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP-LSPLATPPPQAPPA 399
A P PP+ +P PA + L P+ + ++ LP PP L PL++ PP+
Sbjct: 924 AMPHIKPPPTTP-IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPS 982
Query: 400 LALPPLQAPPSP---PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP-VQAPFSPP 455
PPLQ P P+SP P T S P A H P PP Q PF P
Sbjct: 983 AHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPG 1042
Query: 456 ASPPVSPSATPPSQAPP-------------------------SLAAPPLQVP-------- 482
PP++P P + PP S P +Q+
Sbjct: 1043 GPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAE 1102
Query: 483 -PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP 532
P P PP SPS P P A+ + K + + A L +P
Sbjct: 1103 EPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMP 1153
Score = 115 bits (288), Expect = 2e-25
Identities = 156/555 (28%), Positives = 211/555 (38%), Gaps = 98/555 (17%)
Query: 225 RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ 284
+++P++ G P + + SS R+ PSA T + K K + ++
Sbjct: 589 KKQPASPDGRTSPINEDIRSSG-------RNSPSAASTSSNDSKAETVK-KSAKKVKEEA 640
Query: 285 VTPPRKDAAPALGPLSSSPLA--TPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAP 342
+P + + S + A T S Q + P P+ S + +
Sbjct: 641 SSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSD 700
Query: 343 PSPSAPPSLQTLPSPPATPP--SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 400
P + T PS P+ S + +S LQA L +P + + P APP
Sbjct: 701 PKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAP--TGVTPAPSSAPPGT 758
Query: 401 ALPPLQAP-PSPPASPPL-SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 458
P P PS A PP SP A+ +P P QAP +P P +Q +P P
Sbjct: 759 PQLPTPGPTPSATAVPPQGSPTASQAPNQP--------QAPTAPVPHTHIQQ--APALHP 808
Query: 459 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP---QAPPPLAAPPLQLAKP 515
PS PP P PPLQ P + A P +PS PP Q PP P L
Sbjct: 809 QRPPSPHPPPHPSPH---PPLQ-PLTGSAGQPSAPSHAQPPLHGQGPPG----PHSL--- 857
Query: 516 PPQAPPALATP-PLQALPSPPASFPGQAPF--SPSASLPMSPLATP----------PPQA 562
QA P L P P Q PP + GQAP SP+A+ P + L P PP+
Sbjct: 858 --QAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPRE 915
Query: 563 PPVLAAPL----LQVPPSPPAS--PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 616
P+ APL ++ PP+ P P QA + PP +SGP ++ PPPP+
Sbjct: 916 QPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPP------HLSGPS-PFSMNANLPPPPA 968
Query: 617 RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELA------ACHPAA 670
P S+LS H SA P +L S P + A PP + A HP
Sbjct: 969 LKPLSSLS----THHPPSAHPPPLQLMP-QSQPLPSSPAQPPGLTQSQNLPPPPASHPPT 1023
Query: 671 WSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGT 730
AP F P P PP T P P ++TP G PGT
Sbjct: 1024 GLHQVAPQPPFAQHPFVPGGPPPITPPTC------------PSTSTPPAG-------PGT 1064
Query: 731 SGGKAAAGAGAGASS 745
S +GA A S
Sbjct: 1065 SAQPPCSGAAASGGS 1079
Score = 93.2 bits (230), Expect = 9e-19
Identities = 127/480 (26%), Positives = 166/480 (34%), Gaps = 104/480 (21%)
Query: 14 ARTPAARAPGLLTP----RPPGSPR-PPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68
A+ PA +AP +TP PPG+P+ P P TP+A V
Sbjct: 736 AQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAV---------------------- 773
Query: 69 TIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAP---PAKNTSPGPVSSPGRASGTTR 125
P+ PT S + + P ++AP P + SP P P
Sbjct: 774 -----PPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPS------- 821
Query: 126 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT---PGTPSPAMARRSRA 182
P P Q L SA + A A + P G +GP PG P P
Sbjct: 822 PHPPLQP-LTGSAGQPSAPSHA-QPPLHGQGPPGPHSLQAGPLLQHPGPPQP-------- 871
Query: 183 AGTEVGLPRPAPSAR----PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA 238
GLP A + P P S+ + S + R +P PA
Sbjct: 872 ----FGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP------PA 921
Query: 239 SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP 298
++ P ++P P+ + + P H S P P + A PP PAL P
Sbjct: 922 PLAMPHIKPPPTTPIPQLPAPQ-AHKHPPHLSGPSPFSMNANLPP---------PPALKP 971
Query: 299 LSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPP 358
LSS L+T P +A PP L P S PLP +P P Q LP PP
Sbjct: 972 LSS--LSTHHPPSA----HPPPLQLMPQSQ--------PLPSSPAQPPGLTQSQNLPPPP 1017
Query: 359 ATPPSQATTSLGSPTLQATHSFLPS--PPLSPLATPPPQAPPALALPPLQAPPSPPASPP 416
A+ P + A H F+P PP++P P PP A P A PP
Sbjct: 1018 ASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPP--------AGPGTSAQPP 1069
Query: 417 LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 476
S A + L + P SPP PP SPS P PS A+
Sbjct: 1070 CSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPP-PPPRSPSPEPTVVDTPSHAS 1128
Score = 43.9 bits (102), Expect = 6e-04
Identities = 69/257 (26%), Positives = 90/257 (35%), Gaps = 69/257 (26%)
Query: 532 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPP-VLAAPLLQVPPSPPASPTLQAPRRPP 590
PS P+ ++ SA M P QAP V AP +PP +P L P
Sbjct: 713 PSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP----SSAPPGTPQL------P 762
Query: 591 TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE 650
TPGP S + A+ P P S++P+ + H+ + P+
Sbjct: 763 TPGPTPSAT------AVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH-------PQ 809
Query: 651 GGAAASPPPDAELAACHPAAWSRGPAPPL----AFRGAPGAPL-PWPPATGPGSADGLCT 705
+ PPP HP+ P PPL G P AP PP G G
Sbjct: 810 RPPSPHPPP-------HPS-----PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP----- 852
Query: 706 IYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASV 765
GP S P PGP P G P QA G+ PLG A+
Sbjct: 853 -----GPHSLQAGPLLQHPGP-PQPFG--------------LPPQASQGQAPLGTSPAAA 892
Query: 766 VQHLLSRTLLLAAAEGA 782
H +L L A++ A
Sbjct: 893 YPH---TSLQLPASQSA 906
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 138 bits (347), Expect = 2e-32
Identities = 216/842 (25%), Positives = 299/842 (35%), Gaps = 135/842 (16%)
Query: 35 PPPPVTPAALRVLG-AAGAVGRKPLAERA----------GGIGGATIPESAPRAGPTRSA 83
P PVT A+ V AG V +K L+ GG G A+ P P P A
Sbjct: 269 PSEPVTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSGQPLAVA 328
Query: 84 GTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE-ETV 142
+P P + R P P V P T P P G ++ + E
Sbjct: 329 PGLGSSPLV-PAPNVILHRTPTPIQPKPAGVLPPKLYQLT--PKPFAPAGATLTIQGEPG 385
Query: 143 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMA----RRSRAAGTEVGLPRPAPSARP 198
A + +AP+ A + + G P+PA+ ++ A T P+P P A
Sbjct: 386 ALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQP-PGALS 444
Query: 199 RPPT-----EG-----PRKSVSSASEHSTTEPSPA-------------------ARRRPS 229
+P + +G P + + +PA A P
Sbjct: 445 KPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPH 504
Query: 230 AGGGLQRPASRSLSSSATPLS-----SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ 284
GG L + + A PLS +P SA AP QP +
Sbjct: 505 TGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAG 564
Query: 285 VTPPRKDAAPALGPLSSSPL--ATPSPSAALQSQAPPTL--PATPHSSSLTCQLATPLPL 340
P + APA GP +++ L T PSA P L PATP +++ A P+
Sbjct: 565 SLPTQSQPAPA-GPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGE---AAPVLT 620
Query: 341 APPSPSAPPSLQT-----LPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP-----LA 390
P+P APP++ T L P A P QA T + QAT PSP L+ +
Sbjct: 621 VQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTP-QPSPGLASSPEKIVL 679
Query: 391 TPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 450
PP A P L P PL+ P +V + P + P+P
Sbjct: 680 GQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPV 739
Query: 451 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVP-----PSPPASPPM-------SPSATPP 498
P S P+ AP AA PL+ P PS P P+ SP T P
Sbjct: 740 AKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRP 799
Query: 499 PQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 558
P PP + P +++PP + PPL P P A P P + + L P
Sbjct: 800 PSRPP---SRPQSVSRPPSE-------PPLHPCPPPQA-----PPTLPGIFVIQNQLGVP 844
Query: 559 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 618
PP + P AP PP PP P Q P P L P P PPS +
Sbjct: 845 PPASNP---APTAPGPPQPPLRPQSQPPEGP-----------------LPPAPHLPPSST 884
Query: 619 PSSTLSGPDLAGHSSSATSTPEELRGYDS-GPEGGAAASPPPDAELAACHPAAWSRGPAP 677
S+ S + + + T + +L+ S GP + +PPP L P + P P
Sbjct: 885 SSAVASSSETSSRLPAPTPSDFQLQFPPSQGPH--KSPTPPPTLHLV---PEPAAPPPPP 939
Query: 678 PLAFR--GAPGAPLPWPPA---TGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTS- 731
P F+ P LP P A G+ + G +A +L P SP S
Sbjct: 940 PRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASV 999
Query: 732 --GGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGG 789
G+A +G A S +P A + L L + + S L A+ A+ G G
Sbjct: 1000 LVSGQAPSGTPT-APSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKP 1058
Query: 790 PG 791
G
Sbjct: 1059 SG 1060
Score = 138 bits (347), Expect = 2e-32
Identities = 192/700 (27%), Positives = 258/700 (36%), Gaps = 118/700 (16%)
Query: 15 RTPAARAPGLLTPRPPGSPRPPPPV----------------TPAALRVL--GAAGAVGRK 56
+ P A G P+PPG+ P V P + L GA +
Sbjct: 425 KQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQ 484
Query: 57 PLAERAGGIGGATIPESAPRAGPTRSAGTSSRN-----PASRPPASGRGERAPPAKNTSP 111
L+ +GG + +AP G A N P S P A A S
Sbjct: 485 QLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSA 544
Query: 112 GPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGT 171
P+ G+ + P L L ++ A AT + L A + P G
Sbjct: 545 API-QVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTP-DGL 602
Query: 172 PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG 231
PA + V +PAP A P T P ++ P+P A P A
Sbjct: 603 VQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQAT 662
Query: 232 GGLQRPASRSLSSSATPLSSPARSGPSARGTPRA-----PAHPSQP--KPKGLQALRPPQ 284
P S S L P + P+A T + P SQ +G P
Sbjct: 663 TPQPSPGLAS-SPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPAS 721
Query: 285 V----TPPRKDAAPA--------LGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTC 332
V PP +D APA LGP + A+P+P+ + + AP P S SL
Sbjct: 722 VIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPH 781
Query: 333 QLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP 392
Q PL +P PS P+ PP+ PPS+ + P+ PPL P P
Sbjct: 782 Q--APLGDSPHLPSPHPT-----RPPSRPPSRPQSVSRPPS---------EPPLHP--CP 823
Query: 393 PPQAPPALA---LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 449
PPQAPP L + Q PPAS P +P A PQ P L+ PP P
Sbjct: 824 PPQAPPTLPGIFVIQNQLGVPPPASNP-APTAPGPPQPP-------LRPQSQPPEGPLPP 875
Query: 450 APFSPPA--SPPVSPSATPPSQAP-PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 506
AP PP+ S V+ S+ S+ P P+ + LQ PPS P SP+ P P A
Sbjct: 876 APHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPS--QGPHKSPTPPPTLHLVPEPA 933
Query: 507 APPLQLAKPPPQAPPALATPPLQALPSPPA---------------SFPGQAPFSPSASLP 551
APP PPP + T P ALP P A + G AP +P S
Sbjct: 934 APP-----PPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTS 988
Query: 552 MSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 611
+ PL +P AA +L +P +PT AP P P P + P L
Sbjct: 989 LGPLTSP--------AASVLVSGQAPSGTPT--APSHAPAPAPMAATGLPPLL------- 1031
Query: 612 PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 651
P +++ +S L ++A +SS P L+ Y+S G
Sbjct: 1032 -PAENKAFASNLPTLNVAKAASSGPGKPSGLQ-YESKLSG 1069
Score = 89.7 bits (221), Expect = 1e-17
Identities = 207/865 (23%), Positives = 281/865 (32%), Gaps = 218/865 (25%)
Query: 18 AARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRA 77
+A P L P PPP PA + +G + +A IP +AP
Sbjct: 710 SAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLK 769
Query: 78 GPTRSAGTS-----------------SRNPASRPPASGRGERAPPAK---NTSPGPVSSP 117
GP S+ S P SRPP+ + PP++ + P P + P
Sbjct: 770 GPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPP 829
Query: 118 GRASGTTRPGPL---GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP-- 172
T PG Q G+ A P S + GP P P
Sbjct: 830 ------TLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQS----QPPEGPLPPAPHL 879
Query: 173 SPAMARRSRAAGTEVG--LPRPAPS--ARPRPPTEGPRKSVS------------------ 210
P+ + A+ +E LP P PS PP++GP KS +
Sbjct: 880 PPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPP 939
Query: 211 SASEHSTTEPSPAARR-----------------RPSAGGGLQRPASRSLSSSATPLSSPA 253
+ T P PA + + AGG PA+ S+S PL+SPA
Sbjct: 940 PRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGA---PAAPQTSTSLGPLTSPA 996
Query: 254 R----SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 309
SG + GTP AP+H P P L PP + K A L L+ + A+ P
Sbjct: 997 ASVLVSGQAPSGTPTAPSHAPAPAPMAATGL-PPLLPAENKAFASNLPTLNVAKAASSGP 1055
Query: 310 S--AALQSQA-------PPTLPATPHSSSLT-CQLATPLPLAPPSPSAPPSLQ------- 352
+ LQ ++ PPTL + + L L P +A PS +
Sbjct: 1056 GKPSGLQYESKLSGLKKPPTLQPSKEACFLEHLHKHQGSVLHPDYKTAFPSFEDALHRLL 1115
Query: 353 -------TLPSP-PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA----- 399
LPSP + ++ + L+ T + L L L +P A
Sbjct: 1116 PYHVYQGALPSPSDYHKVDEEFETVSTQLLKRTQAMLNKYRLLLLEESRRVSPSAEMVMI 1175
Query: 400 -----------LALPPLQAPPSPPASPPLS-----PLATPSP----QAPNALAVHLLQAP 439
LAL A P S P+A S L+ A
Sbjct: 1176 DRMFIQEEKTTLALDKQLAKEKPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGAS 1235
Query: 440 FSPPPSPPVQ-------APFSPP-----ASPPVSPSATPPSQAP----------PSLAAP 477
PPP P + A SP AS +S S++ S A PS P
Sbjct: 1236 TQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRP 1295
Query: 478 P-------------LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALA 524
P L++ S + +A P PPP A L++A+PPP+ PP
Sbjct: 1296 PIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPA-TLKVAEPPPRPPPP-- 1352
Query: 525 TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV-------PPSP 577
P P G P A+ PL T AP PL + P +P
Sbjct: 1353 -------PPPTGQMNGTVDHPPPAAPERKPLGT----APHCPRLPLRKTYRENVGGPGAP 1401
Query: 578 PASPTLQAPRRPPTPGP---DTSVSGPRLTLA---------LAPGPPPPPSRSPSSTLSG 625
+P +A P P P D + SG LA + GPPP P+ S +
Sbjct: 1402 EGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGD 1461
Query: 626 PDLAGHSSSATSTPEELRGYDSGPEGGAAA----SPPPDAELAACHPA---------AWS 672
PD A P R P+ A+ SP D A A
Sbjct: 1462 PDW-----EAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPG 1516
Query: 673 RGPAPPLAFRGAPGAPLPWPPATGP 697
R PAP + G P PP P
Sbjct: 1517 RTPAPSYPHAASAGTPASPPPLHRP 1541
Score = 77.0 bits (188), Expect = 7e-14
Identities = 205/874 (23%), Positives = 295/874 (33%), Gaps = 144/874 (16%)
Query: 4 KRDKAKAGAAARTPAARAPG-LLTPRP-PG---SPRP-----PPPVTPAALRVLGAAGAV 53
++ +A+ A TP A AP TP+P PG SP PP TP A+ +
Sbjct: 640 QQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMF 699
Query: 54 GRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPAS---GRGERAPPAKNT- 109
+ +++ G P + A SA +++PA P + G G +AP ++ +
Sbjct: 700 LPQERSQQPLSAEG---PHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASP 756
Query: 110 -------SPGPVSSPGRASGTTRP--GPLGQKGLRISAEETVARGKATEAPKRSALSAGA 160
+ P+ PG +S + P PLG S T + P+ ++S
Sbjct: 757 APAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQ--SVSRPP 814
Query: 161 RRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP 220
P P +P ++G+P PA + P P GP + P
Sbjct: 815 SEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPA--SNPAPTAPGPPQPPLRPQSQPPEGP 872
Query: 221 SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL 280
P A P + A S S +++ L +P S + P H S P L +
Sbjct: 873 LPPAPHLPPSSTS---SAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLV 929
Query: 281 RPPQVTPPRKDAAPALGPLSSSPL-ATPSPSAALQS--QAPPTL---------PATPHSS 328
P PP P + ++P A P P A L+ Q P + PA P +S
Sbjct: 930 PEPAAPPP---PPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTS 986
Query: 329 SLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH----SFLPSP 384
+ L +P S AP T PS P A T L P L A + S LP+
Sbjct: 987 TSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGL-PPLLPAENKAFASNLPTL 1045
Query: 385 PLSPLATPPPQAPPALA----LPPLQAPPSPPASPPLSPLA---------------TPSP 425
++ A+ P P L L L+ PP+ S L T P
Sbjct: 1046 NVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEACFLEHLHKHQGSVLHPDYKTAFP 1105
Query: 426 QAPNAL----AVHLLQAPF-SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 480
+AL H+ Q SP V F ++ + + ++ L +
Sbjct: 1106 SFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETVSTQLLKRTQAMLNKYRLLLLEESRR 1165
Query: 481 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ----APPALATPPLQALPSPPA 536
V PS M Q A QLAK P + +L P A S
Sbjct: 1166 VSPSAE----MVMIDRMFIQEEKTTLALDKQLAKEKPDEYVSSSRSLGLPI--AASSEGH 1219
Query: 537 SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT 596
PG P S SA P A+ P PP L L+ SP++ R + +
Sbjct: 1220 RLPGHGPLSSSA-----PGASTQP--PPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSS 1272
Query: 597 SVSGPRLTL-ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAA 655
S S +L A GP P +R P T Y++ G
Sbjct: 1273 SSSSAASSLDADEDGPMPSRNRPPIKT----------------------YEARSRIGLKL 1310
Query: 656 SPPPDAELA-ACHPAAWS---RGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEG 711
+A L+ H A + P PP + A P P PP G +G
Sbjct: 1311 KIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAA 1370
Query: 712 PE---------------SATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGEL 756
PE T PG GT G+A G S +P A++ E
Sbjct: 1371 PERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGG------SPAPLPAKVDEA 1424
Query: 757 PLGALQ--ASVVQHLLSRTLLLAAAEGAAGGSGG 788
G ++ A+V L R L E AA + G
Sbjct: 1425 TSGLIRELAAVEDELYQRMLKGPPPEPAASAAQG 1458
Score = 56.2 bits (134), Expect = 1e-07
Identities = 99/381 (25%), Positives = 133/381 (34%), Gaps = 108/381 (28%)
Query: 182 AAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSP-----AARRRPSAGGG--- 233
++ +GLP A S R P GP +SS++ ++T+P P R AGG
Sbjct: 1203 SSSRSLGLPIAASSEGHRLPGHGP---LSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSV 1259
Query: 234 LQRPASRSLSSSATPLSS------------PARSGPSAR--------------------- 260
AS SLSSS++ S+ P+R+ P +
Sbjct: 1260 TWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLS 1319
Query: 261 ----GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQ 316
T P H P P L+ PP PP P P+ +
Sbjct: 1320 KVVHNTALDPVHQPPPPPATLKVAEPPPRPPP-----------------PPPPTGQMNGT 1362
Query: 317 APPTLPATPHSSSL-TCQLATPLPL---------APPSPSAPPSLQTLPSPPATPPS--- 363
PA P L T LPL P +P P+ + PA P+
Sbjct: 1363 VDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVD 1422
Query: 364 QATT----SLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPA------ 413
+AT+ L + + L PP P A+ A P +AP PPA
Sbjct: 1423 EATSGLIRELAAVEDELYQRMLKGPPPEPAAS----AAQGTGDPDWEAPGLPPAKRRKSE 1478
Query: 414 SPPL--SPLATPSPQAPNALAVH----------LLQAP-FSPPPSPPVQAPFSPPASPPV 460
SP + + ++ SPQ + L H L QAP +P PS P A PASPP
Sbjct: 1479 SPDVDQASFSSDSPQ-DDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPP 1537
Query: 461 --SPSATPPSQAPPSLAAPPL 479
P A PPS L A L
Sbjct: 1538 LHRPEAYPPSSHNGGLGARTL 1558
Score = 51.6 bits (122), Expect = 3e-06
Identities = 101/396 (25%), Positives = 129/396 (32%), Gaps = 84/396 (21%)
Query: 13 AARTPAARAPGL--LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70
AA + R PG L+ PG+ PPP P L + R GG GG+
Sbjct: 1213 AASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVI--------------RHGGAGGSPS 1258
Query: 71 PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG 130
A RA + S+ +SS + AS A G P++N P
Sbjct: 1259 VTWA-RASSSLSSSSSSSSAASSLDADEDGPM--PSRNRPP------------------- 1296
Query: 131 QKGLRISAEETVAR-GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189
I E +R G + + + LS P P P A +V
Sbjct: 1297 -----IKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPP-------PATLKVAE 1344
Query: 190 PRPAPSARP-----------RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR-- 236
P P P P PP P + + H P R G G
Sbjct: 1345 PPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGT 1404
Query: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP-------QVTPPR 289
PA R+ S PL PA+ + G R A + + PP Q T
Sbjct: 1405 PAGRARGGSPAPL--PAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGTGDP 1462
Query: 290 KDAAPALGPLSSSPLATPS-PSAALQSQAPPTLPATPH-----SSSLTCQLA---TPLPL 340
AP L P +P A+ S +P T H S L Q A TP P
Sbjct: 1463 DWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPS 1522
Query: 341 APPSPSA--PPSLQTLPSPPATPPSQATTSLGSPTL 374
P + SA P S L P A PPS LG+ TL
Sbjct: 1523 YPHAASAGTPASPPPLHRPEAYPPSSHNGGLGARTL 1558
Score = 48.5 bits (114), Expect = 3e-05
Identities = 90/388 (23%), Positives = 123/388 (31%), Gaps = 81/388 (20%)
Query: 143 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 202
A + P LS+ A ++ P P P+ + R A G+ AR
Sbjct: 1214 ASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSP-----SVTWARASSSL 1268
Query: 203 EGPRKSVSSASEHSTTEPSPA-ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG 261
S S+AS E P +R RP ++ +RS + A
Sbjct: 1269 SSSSSSSSAASSLDADEDGPMPSRNRPP----IKTYEARSRIGLKLKIKQEAGLSKVVHN 1324
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTL 321
T P H P P L+ PP PP P P+ +
Sbjct: 1325 TALDPVHQPPPPPATLKVAEPPPRPPP-----------------PPPPTGQMNGTVDHPP 1367
Query: 322 PATPHSSSL-TCQLATPLPL---------APPSPSAPPSLQTLPSPPATPPS---QATTS 368
PA P L T LPL P +P P+ + PA P+ +AT+
Sbjct: 1368 PAAPERKPLGTAPHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSG 1427
Query: 369 L----GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPA------SPPL- 417
L + + L PP P A+ A P +AP PPA SP +
Sbjct: 1428 LIRELAAVEDELYQRMLKGPPPEPAAS----AAQGTGDPDWEAPGLPPAKRRKSESPDVD 1483
Query: 418 -SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 476
+ ++ SPQ + L HL A S QAP A
Sbjct: 1484 QASFSSDSPQ-DDTLTEHLQSA----------------------IDSILNLQQAPGRTPA 1520
Query: 477 PPLQVPPSPPASPPMSPSATPPPQAPPP 504
P P + A P SP P+A PP
Sbjct: 1521 P--SYPHAASAGTPASPPPLHRPEAYPP 1546
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 137 bits (345), Expect = 4e-32
Identities = 168/600 (28%), Positives = 218/600 (36%), Gaps = 102/600 (17%)
Query: 169 PGTPSPAMARRSRAAGTEV--GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 226
P TP A + A G V G P A A P P EG + + EP PA R
Sbjct: 45 PRTPE-VRAAAAGALGNHVVSGSPAGAAGAGPAAPAEG--------APGAAPEPPPAGRA 95
Query: 227 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT 286
RP GG P R GP + P PA P+ P K LRPP
Sbjct: 96 RPGGGG-------------------PQRPGPPSPRRPLVPAGPAPPAAK----LRPP--- 129
Query: 287 PPRKDAAPALGPLSSSPLATPSPSAALQSQAP---PTLPATPHSSSLTCQLATPLPLAPP 343
P S+ P P+AA + P P PA P + A P P P
Sbjct: 130 -----------PEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGP 178
Query: 344 SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSP------PLSPLATPPPQAP 397
P P P PA P + T + + L + H+ P+ P + L P P AP
Sbjct: 179 GPGPGPG----PGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAP 234
Query: 398 -PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA-PFSPP 455
+ PP +PPA SP A P+P AP A AP PPP+P A P P
Sbjct: 235 GTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAA-------APPPPPPAPATLARPPGHP 287
Query: 456 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP 515
A PP + A PP A + + P+P A P S P P A AP ++ P
Sbjct: 288 AGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESP 347
Query: 516 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL---ATPPPQAPPVLAAPLLQ 572
+QA P + P S +AS+ + P A P P A P A
Sbjct: 348 ---------KRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPT 398
Query: 573 VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL---ALAPGPPPPPSRSPSSTLSGPDLA 629
P A Q+ R PT + SG R TL LAP P PP ++P++ +
Sbjct: 399 GLPKGAAGAVTQSLSRTPT----ATTSGIRATLTPTVLAPRLPQPP-QNPTNIQNFQLPP 453
Query: 630 GHSSSATSTPEELR-GYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP 688
G + + L + + A A P +A PA + P ++ APG P
Sbjct: 454 GMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAP-RPATPTSAPPVQISTVQAPGTP 512
Query: 689 LPWPPATGPGSADGLCTIYETEGPESATPAPGAL---DPGPSPGTSGGKAAAGAGAGASS 745
+ T TI + T P A PG P G AA A G ++
Sbjct: 513 IIARQVTP-------TTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTAT 565
Score = 114 bits (286), Expect = 3e-25
Identities = 153/559 (27%), Positives = 198/559 (35%), Gaps = 95/559 (16%)
Query: 37 PPVTPAALRVLG-------AAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRN 89
P V AA LG AGA G P A G G A P A RA P
Sbjct: 48 PEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGP 107
Query: 90 PASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE 149
P+ R P G P AK RP P G + G
Sbjct: 108 PSPRRPLVPAGPAPPAAK----------------LRPPPEG------------SAGSCAP 139
Query: 150 APKRSALSAGARRDTSGPT-PGTPSPAMARRSRAAGTEVGLPRPAPS-ARPRPPTEGPRK 207
P +A++AG +GP P P+ AR G G P P P +P P
Sbjct: 140 VPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPG-PGPGPGPGKPAGPGAAQTL 198
Query: 208 SVSSA---SEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 264
+ S+A S H+ P+A L +PA+ T + +P G +A P
Sbjct: 199 NGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAA-----PGTVIQTPPFVGAAAPPAPA 253
Query: 265 APAHPSQPKPKGLQALRPPQVTPPRKDAAPA---LGPLSSSPLATPSPSAALQ----SQA 317
AP+ P+ P P A PP P A P GP +++P A P P+AA A
Sbjct: 254 APSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAP-AVPPPAAAQNGGSAGAA 312
Query: 318 PPTLPATPHSSSLTCQLATPLPLAPPSP------------SAPPSLQTLPSPPATPPSQA 365
P PA + ++ Q A P+P +APP+ QTL + + P S A
Sbjct: 313 PAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAA--SGPASTA 370
Query: 366 TTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS- 424
+ + PT+Q LPSP A PP AP P A + S +P AT S
Sbjct: 371 ASMVIGPTMQGA---LPSP-----AAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSG 422
Query: 425 ---PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV 481
P LA L Q P +P Q P P L P Q
Sbjct: 423 IRATLTPTVLAPRLPQPPQNPTNIQNFQLP----------PGMVLVRSENGQLLMIPQQA 472
Query: 482 PPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQ 541
A P T P+ P +APP+Q++ P +A Q P+ Q
Sbjct: 473 LAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIAR---QVTPTTIIKQVSQ 529
Query: 542 A--PFSPSASLPMSPLATP 558
A PSA+L SP P
Sbjct: 530 AQTTVQPSATLQRSPGVQP 548
Score = 108 bits (269), Expect = 3e-23
Identities = 110/371 (29%), Positives = 139/371 (37%), Gaps = 24/371 (6%)
Query: 393 PPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 452
P A A P + P PP + A P P + P P P A
Sbjct: 67 PAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKL 126
Query: 453 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 512
PP A P+ A + P P+ PA P + P P P P
Sbjct: 127 RPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGP 186
Query: 513 AKPPPQAPPALATPPLQALPSPPASFPGQAPFS--PSASLPMSPLATPPP--QAPPVL-- 566
KP L S A+ P + + P+A LP+ A P Q PP +
Sbjct: 187 GKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGA 246
Query: 567 AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG-PPPPPSRSPSSTLSG 625
AAP PSPPA+P AP P P P TLA PG P PP+ +P+
Sbjct: 247 AAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPA-----TLARPPGHPAGPPTAAPAVPPPA 301
Query: 626 PDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAP 685
G S+ A P G GP G + P P A AA PA + +P + AP
Sbjct: 302 AAQNGGSAGAAPAPAPAAG---GP-AGVSGQPGPGA--AAAAPAPGVKAESPKRVVQAAP 355
Query: 686 GAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGG--KAAAGAGAGA 743
A A+GP S I T + A P+P A+ P P+PGT G K AAGA +
Sbjct: 356 PAAQTL-AASGPASTAASMVIGPT--MQGALPSPAAVPP-PAPGTPTGLPKGAAGAVTQS 411
Query: 744 SSRSPKQARLG 754
SR+P G
Sbjct: 412 LSRTPTATTSG 422
Score = 107 bits (266), Expect = 6e-23
Identities = 146/518 (28%), Positives = 183/518 (35%), Gaps = 79/518 (15%)
Query: 8 AKAGAAARTPAARA-PGLLTPRPPGSPRPPPPVT------PAA-LR--VLGAAGAVGRKP 57
A A PA RA PG P+ PG P P P+ PAA LR G+AG+ P
Sbjct: 82 APGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVP 141
Query: 58 LAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSP 117
A A PE AP AGP + AG PA+ +G G P PGP
Sbjct: 142 AAAAV-----AAGPEPAP-AGPAKPAG-----PAALAARAGPGPGPGPGPGPGPGPGKPA 190
Query: 118 GRASGTTRPGP---LGQKGLRISAEETVARGKATEAPKRSALSAGARRDT-------SGP 167
G + T G L A V G A P + G T + P
Sbjct: 191 GPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPP 250
Query: 168 TPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 227
P PSP A A P PAP+ RPP H P+ A
Sbjct: 251 APAAPSPPAAPAPAAPAAAPPPPPPAPATLARPP------------GHPAGPPTAAPAVP 298
Query: 228 PSAGGGLQRPASRSLSSSATPLSSPARSGP---SARGTPRAPAHPSQPKPKGLQALRPPQ 284
P A A S+ A P +PA GP S + P A A P K R Q
Sbjct: 299 PPAA------AQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQ 352
Query: 285 VTPPRKDAAPALGPLS--SSPLATPSPSAALQSQA--PPTLPATPHSSSLTCQLATPLPL 340
PP A GP S +S + P+ AL S A PP P T P
Sbjct: 353 AAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGT--------------PT 398
Query: 341 APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 400
P +A Q+L P S +L +PT+ A LP PP +P Q PP +
Sbjct: 399 GLPKGAAGAVTQSLSRTPTATTSGIRATL-TPTVLAPR--LPQPPQNPTNIQNFQLPPGM 455
Query: 401 ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ-APFSPPASPP 459
L +++ P LA QA + P +P +PPVQ + P +P
Sbjct: 456 VL--VRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPI 513
Query: 460 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 497
++ TP + A Q P A+ SP P
Sbjct: 514 IARQVTPTTIIKQVSQA---QTTVQPSATLQRSPGVQP 548
Score = 80.9 bits (198), Expect = 5e-15
Identities = 96/339 (28%), Positives = 122/339 (35%), Gaps = 49/339 (14%)
Query: 482 PPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP---PQ--APPALATPPLQALPSPPA 536
P + P +P+ P AP P PP A+P PQ PP+ P + A P+PPA
Sbjct: 67 PAGAAGAGPAAPAEGAPGAAPEP---PPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPA 123
Query: 537 SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL-LQVPPSPPASPTLQAPRRPPTPGPD 595
+ P + S P P A V A P P+ PA P A R P PGP
Sbjct: 124 AKLRPPPEGSAGS------CAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPG 177
Query: 596 TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE----- 650
GP PGP P + TL+G +S A + L ++GP
Sbjct: 178 PG-PGP------GPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSL--VNNGPAALLPL 228
Query: 651 ------GGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLC 704
G +PP A PAA P+PP A AP AP PP P A
Sbjct: 229 PKPAAPGTVIQTPPFVGAAAPPAPAA----PSPPAA--PAPAAPAAAPPPPPPAPATLAR 282
Query: 705 TIYETEGPESATPA---PGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGAL 761
GP +A PA P A G S G + A A G S P P +
Sbjct: 283 PPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGV 342
Query: 762 QASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTG 800
+A + ++ AA A + GP V G
Sbjct: 343 KAESPKRVVQ-----AAPPAAQTLAASGPASTAASMVIG 376
Score = 70.1 bits (170), Expect = 8e-12
Identities = 138/595 (23%), Positives = 193/595 (32%), Gaps = 124/595 (20%)
Query: 10 AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPA-----ALRVLGAAGAV-GRKPLAERAG 63
A AAA P AP L RPPG P PP PA A + G+AGA P A
Sbjct: 265 APAAAPPPPPPAPATLA-RPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPA 323
Query: 64 GIGGATIPESAPRA-GPTRSAGTSSRNPASRPPA------SGRGERA------PPAKNTS 110
G+ G P +A A P A + R + PPA SG A P +
Sbjct: 324 GVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGAL 383
Query: 111 PGPVSSPGRASGTTRPGPLGQ----------------KGLRISAEETVARGKATEAPKRS 154
P P + P A GT P G G+R + TV + + P+
Sbjct: 384 PSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNP 443
Query: 155 ALSAGAR--------RDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPR 206
+ R +G P A+A+ A + P+ + RP PT P
Sbjct: 444 TNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQ---PQTTMAPRPATPTSAPP 500
Query: 207 KSVSS----------------------ASEHSTTEPSPAARRRPSAG-----GGLQRPAS 239
+S+ + +T +PS +R P GG + AS
Sbjct: 501 VQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTAS 560
Query: 240 RSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPL 299
+++A +P R+ P A T A + K K+ L L
Sbjct: 561 LG-TATAVQTGTPQRTVPGATTTSSAATETMENVKKC-------------KNFLSTLIKL 606
Query: 300 SSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQL-----ATPLPLAPP----------- 343
+SS + +A ++ L + T +L ++P P P
Sbjct: 607 ASSGKQSTETAANVKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQ 666
Query: 344 -SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALAL 402
+P + +Q P P SQATT+L + L + S + + PP L+L
Sbjct: 667 LTPDSAAFIQQSQQQPPPPTSQATTALTAVVLSS--SVQRTAGKTAATVTSALQPPVLSL 724
Query: 403 -PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 461
P Q P +PL P P AL PP Q P P
Sbjct: 725 TQPTQVGVGKQGQP--TPLVIQQPPKPGAL--------IRPPQVTLTQTPMVALRQPHNR 774
Query: 462 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP 516
T P Q + PLQ P P P + P AA K P
Sbjct: 775 IMLTTPQQ----IQLNPLQ--PVPVVKPAVLPGTKALSAVSAQAAAAQKNKLKEP 823
Score = 69.7 bits (169), Expect = 1e-11
Identities = 91/320 (28%), Positives = 107/320 (33%), Gaps = 40/320 (12%)
Query: 499 PQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 558
P+ P AA L PA A A P+ A PG AP P A P
Sbjct: 45 PRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGA--PGAAPEPPPAGRARPGGGGP 102
Query: 559 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 618
PP PL+ P+PPA A RPP G S + A+A GP P P+
Sbjct: 103 QRPGPPSPRRPLVPAGPAPPA-----AKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPA-G 156
Query: 619 PSSTLSGPDLAGHSSSATST-----PEELRGYDSGPEGGAAASPPPDAELAACHPAAW-- 671
P+ LA + P G +GP GAA + A L H AA
Sbjct: 157 PAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGP--GAAQTLNGSAALLNSHHAAAPA 214
Query: 672 ----SRGPAP--PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPG 725
+ GPA PL APG + PP G + P A PA P
Sbjct: 215 VSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPP 274
Query: 726 PSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGG 785
P+P T AG P A P A Q A A A
Sbjct: 275 PAPATLARPPGHPAG-------PPTAAPAVPPPAAAQNGGS----------AGAAPAPAP 317
Query: 786 SGGGPGGAEGGGVTGGARAA 805
+ GGP G G G A AA
Sbjct: 318 AAGGPAGVSGQPGPGAAAAA 337
Score = 48.9 bits (115), Expect = 2e-05
Identities = 59/184 (32%), Positives = 64/184 (34%), Gaps = 33/184 (17%)
Query: 629 AGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP 688
A H A TPE +R +G G S P A GPA P GAPGA
Sbjct: 38 AHHHHLAPRTPE-VRAAAAGALGNHVVSGSPAGAAGA--------GPAAPA--EGAPGAA 86
Query: 689 LPWPPATGPGSADGLCTIYETEGPES-------ATPAPGALDPGPSPGTSGGKAAAGAGA 741
P PP G G + GP S A PAP A P P S G A A
Sbjct: 87 -PEPPPAGRARPGGGGP--QRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAA 143
Query: 742 GASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGG 801
A + P+ A G A LAA G G G GPG G G G
Sbjct: 144 AAVAAGPEPAPAGPAKPAGPAA------------LAARAGPGPGPGPGPGPGPGPGKPAG 191
Query: 802 ARAA 805
AA
Sbjct: 192 PGAA 195
>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 673
Score = 133 bits (335), Expect = 6e-31
Identities = 177/690 (25%), Positives = 253/690 (36%), Gaps = 107/690 (15%)
Query: 15 RTPAARAP------GLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68
RTP+ +P LT P + P T + + A G P A G A
Sbjct: 6 RTPSRASPTRTPSTASLTGTPSRASLTGTPSTASLMGTPSRASLTGTPPRASLKGTTSMA 65
Query: 69 TIPESAPRAGPTRSAGTS--SRNPASR-----PPASGRGERAPPA----KNTSPGPVSSP 117
++ S RA TR +S +R P+ PP + R P A + ++ SP
Sbjct: 66 SLMVSPSRASLTRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRASLMRRPSTASLTRSP 125
Query: 118 GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMA 177
RAS TT P R S T + A P R++L+ R TPS A
Sbjct: 126 SRASLTTTPS-------RASLSMTPSTAAALTMPSRASLT---RTPPRASLTMTPSTASL 175
Query: 178 RRSRAAGTEVGLP-RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR 236
R+ + G+P R +P+ P + S +S + + R S G R
Sbjct: 176 TRTPPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTGTPPRASPTGSPPR 235
Query: 237 PASRSLSSSATPLSSPARSGP-------------SARGTPRAPAHPSQPKPKGLQALRPP 283
+ + S+A + +P R+ P S R P+ PS P G +
Sbjct: 236 ASLSMMPSTALLIRTPPRASPTGMLSRTSLTKMDSTASITRTPSRPSTASPTGTPSRASL 295
Query: 284 QVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPP 343
+TP L +SP S ++ + + ++ TP +S+T + P P
Sbjct: 296 SMTPSTASLMRMLP--RASPTGMLSRTSLTKMDSTASISRTPPRASITRTPSRASPTGKP 353
Query: 344 SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP-LSPLATP--------PP 394
S ++P + SP +P + + T L S T S +PP SP TP PP
Sbjct: 354 STASPTGTPSRASPTGSPSTASLTGLSS-----TASPTGTPPRASPTGTPSTASLTRKPP 408
Query: 395 QAPPALALP------------PLQAPP--SPPASPP-LSPLATPSPQAPNALAVHLLQAP 439
+A P L P + PP SP +PP SP TPS +P Q+
Sbjct: 409 RASPTGMLSRTSITKMDSTASPTRTPPRASPTGTPPRASPTGTPSRASPTGT-----QST 463
Query: 440 FSPPPSPPVQAPFSPP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 497
SP SP +P P ASP SPS ++ P + ++ S +P + S T
Sbjct: 464 ASPTGSPSTASPTGSPSTASPTGSPSRASLTRTPSRASLTKMESTASITRTPSRA-SPTW 522
Query: 498 PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPA----SFPGQAPFS-------- 545
P P +P LA P TP +L P+ + P +A +
Sbjct: 523 TPSTASPTGSPSTALAMGSPSRAALTRTPSRASLTRTPSRASLTTPSRASLTRTPSTVLL 582
Query: 546 ----PSASLPMSPLATPPPQAPPVL-------AAPLLQVPPSPPASPTLQAPRRPPTPGP 594
PSAS P T P P A + + PP ASPT PR PT P
Sbjct: 583 TRMPPSASPTGMPSRTSPTGMPSSALLTKMDSTASITRTPPR--ASPTETPPRASPTGTP 640
Query: 595 DTSVSGPRLTLALAPGPPPPPSRSPSSTLS 624
+ P T A PP SP+ T S
Sbjct: 641 PR--ASPTGTPPRASPTGTPPRASPTGTPS 668
Score = 115 bits (289), Expect = 1e-25
Identities = 145/533 (27%), Positives = 209/533 (39%), Gaps = 82/533 (15%)
Query: 15 RTPAARAPGLLTPR--PPGSPRPPPPV----TPAALRVLGAAGAVGRKPLAERAGGIGGA 68
RTP +P + R P G P T + R L A G P A G A
Sbjct: 177 RTPPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTGTPPRASPTGSPPRA 236
Query: 69 TI---PESA------PRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGR 119
++ P +A PRA PT G SR ++ ++ R P +T+ P +P R
Sbjct: 237 SLSMMPSTALLIRTPPRASPT---GMLSRTSLTKMDSTASITRTPSRPSTA-SPTGTPSR 292
Query: 120 ASGTTRP---------------GPLGQKGLR-----ISAEETVARGKATEAPKRSALSAG 159
AS + P G L + L S T R T P R+ S
Sbjct: 293 ASLSMTPSTASLMRMLPRASPTGMLSRTSLTKMDSTASISRTPPRASITRTPSRA--SPT 350
Query: 160 ARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTE 219
+ T+ PT GTPS A S + + GL A S PP P + S+AS T
Sbjct: 351 GKPSTASPT-GTPSRASPTGSPSTASLTGLSSTA-SPTGTPPRASPTGTPSTAS---LTR 405
Query: 220 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH-PSQPKPKGLQ 278
P R S G L R + + S+A+P +P R+ P+ +P PS+ P G Q
Sbjct: 406 KPP----RASPTGMLSRTSITKMDSTASPTRTPPRASPTGTPPRASPTGTPSRASPTGTQ 461
Query: 279 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPL 338
+ A+P P ++SP +PS ++ S + +L TP +SLT +T
Sbjct: 462 ST-----------ASPTGSPSTASPTGSPSTASPTGSPSRASLTRTPSRASLTKMESTAS 510
Query: 339 PLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH------SFLPSPPLSPLATP 392
PS ++P + SP +P + ++GSP+ A S +P + L TP
Sbjct: 511 ITRTPSRASPTWTPSTASPTGSPST--ALAMGSPSRAALTRTPSRASLTRTPSRASLTTP 568
Query: 393 PPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 452
+ L P ASP P T P++ + + + S +PP
Sbjct: 569 SRASLTRTPSTVLLTRMPPSASPTGMPSRTSPTGMPSSALLTKMDSTASITRTPP----- 623
Query: 453 SPPASPPVSPSATPPSQAPPSLAAPPLQVPP--SPPASPP-MSPSATPPPQAP 502
ASP +P P+ PP A P PP SP +PP SP+ TP +P
Sbjct: 624 --RASPTETPPRASPTGTPP--RASPTGTPPRASPTGTPPRASPTGTPSRASP 672
Score = 103 bits (257), Expect = 7e-22
Identities = 165/668 (24%), Positives = 236/668 (35%), Gaps = 123/668 (18%)
Query: 141 TVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRP 200
T +R T P ++L+ R + TP T S M SRA+ T G P
Sbjct: 7 TPSRASPTRTPSTASLTGTPSRASLTGTPSTAS-LMGTPSRASLT--GTP---------- 53
Query: 201 PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSAR 260
PR S+ + ++ SP+ L R S SL + ++S R P A
Sbjct: 54 ----PRASLKGTTSMASLMVSPSR-------ASLTRMQSSSLLTRTPSMASLKRMPPRAS 102
Query: 261 GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPT 320
T P +P R P A+ P +S TPS +AAL + +
Sbjct: 103 RTRTLPRASLMRRPSTASLTRSPS------RASLTTTPSRASLSMTPSTAAALTMPSRAS 156
Query: 321 LPATPHSSSLTCQLAT-PLPLAPP-----------SPSAPPSLQTL-------------- 354
L TP +SLT +T L PP SP+ PS +L
Sbjct: 157 LTRTPPRASLTMTPSTASLTRTPPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLS 216
Query: 355 -PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL----------ALP 403
SP TPP + T GSP +A+ S +PS L + TPP +P + +
Sbjct: 217 RASPTGTPPRASPT--GSPP-RASLSMMPSTALL-IRTPPRASPTGMLSRTSLTKMDSTA 272
Query: 404 PLQAPPSPP--ASPPLSPLATPSPQAPNALAVHLLQAPFSP------------------- 442
+ PS P ASP +P P+ ++ + SP
Sbjct: 273 SITRTPSRPSTASPTGTPSRASLSMTPSTASLMRMLPRASPTGMLSRTSLTKMDSTASIS 332
Query: 443 --PP------SPPVQAPFSPP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPP-M 491
PP +P +P P ASP +PS P+ +P + + L SP +PP
Sbjct: 333 RTPPRASITRTPSRASPTGKPSTASPTGTPSRASPTGSPSTASLTGLSSTASPTGTPPRA 392
Query: 492 SPSATP--------PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 543
SP+ TP PP+A P + K A P P +PP + P
Sbjct: 393 SPTGTPSTASLTRKPPRASPTGMLSRTSITKMDSTASPTRTPPRASPTGTPPRASP---T 449
Query: 544 FSPSASLPMSPLATPPPQAPPVLAAPL-LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPR 602
+PS + P +T P P A+P SP SP+ + R P+ T +
Sbjct: 450 GTPSRASPTGTQSTASPTGSPSTASPTGSPSTASPTGSPSRASLTRTPSRASLTKME--- 506
Query: 603 LTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR-GYDSGPEGGAAASPPPDA 661
+ A P SP+ T S G S+A + R P + P A
Sbjct: 507 ---STASITRTPSRASPTWTPSTASPTGSPSTALAMGSPSRAALTRTPSRASLTRTPSRA 563
Query: 662 ELAACHPAAWSRGPAPPLAFRGAPGA-PLPWPPATGPGSADGLCTIYETEGPESATPAPG 720
L A+ +R P+ L R P A P P T P + + + S T P
Sbjct: 564 SLTTPSRASLTRTPSTVLLTRMPPSASPTGMPSRTSPTGMPSSALLTKMDSTASITRTPP 623
Query: 721 ALDPGPSP 728
P +P
Sbjct: 624 RASPTETP 631
Score = 87.8 bits (216), Expect = 4e-17
Identities = 149/602 (24%), Positives = 227/602 (37%), Gaps = 85/602 (14%)
Query: 292 AAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSL 351
A P P +SP TPS ++ + + +L TP ++SL + TP + SL
Sbjct: 2 APPTRTPSRASPTRTPSTASLTGTPSRASLTGTPSTASL---MGTPSRASLTGTPPRASL 58
Query: 352 QTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP--PLQAPP 409
+ S + S + SL +Q++ +P ++ L PP+A LP L P
Sbjct: 59 KGTTSMASLMVSPSRASL--TRMQSSSLLTRTPSMASLKRMPPRASRTRTLPRASLMRRP 116
Query: 410 SPPA---SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 466
S + SP + L T +A ++ A P + + P P AS ++PS
Sbjct: 117 STASLTRSPSRASLTTTPSRASLSMTPSTAAALTMPSRASLTRTP--PRASLTMTPSTAS 174
Query: 467 PSQAPPSLAAPPLQVPPSPPASPP-------------------MSPSATPPPQAPPPLAA 507
++ PP + + SP P SP+ TPP + P +
Sbjct: 175 LTRTPPRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTGTPPRAS--PTGS 232
Query: 508 PPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL--ATPPPQAPPV 565
PP P + TPP +A P+ S +AS+ +P +T P P
Sbjct: 233 PPRASLSMMPSTALLIRTPP-RASPTGMLSRTSLTKMDSTASITRTPSRPSTASPTGTPS 291
Query: 566 LAAPLLQVPPS--------PPASPTLQAPRRPPTPGPDT---SVSGPRLTLALAP----- 609
A+ L + PS P ASPT R T T S + PR ++ P
Sbjct: 292 RAS--LSMTPSTASLMRMLPRASPTGMLSRTSLTKMDSTASISRTPPRASITRTPSRASP 349
Query: 610 -------GPPPPPSR-SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAAS--PPP 659
P PSR SP+ + S L G SS+A+ T R +G A+ + PP
Sbjct: 350 TGKPSTASPTGTPSRASPTGSPSTASLTGLSSTASPTGTPPRASPTGTPSTASLTRKPPR 409
Query: 660 DAELAACHPAAWSRGPAPPLAFRGAPGA-PLPWPPATGPGSADGLCTIYETEGPESATPA 718
+ + ++ + R P A P PP P + T+ S T +
Sbjct: 410 ASPTGMLSRTSITKMDSTASPTRTPPRASPTGTPPRASPTGTPSRASPTGTQSTASPTGS 469
Query: 719 PGALDPGPSPGTSGGKAAAGAGAGAS-SRSPKQARLGELPLGALQASVVQHLLSRTLLLA 777
P P SP T+ + G+ + AS +R+P +A L ++ + S T +
Sbjct: 470 PSTASPTGSPSTA---SPTGSPSRASLTRTPSRASLTKM----------ESTASITRTPS 516
Query: 778 AAEGAAGGSGGGPGGAEGGGVTGG--ARAAL----SDAELGRWAELLSPLDESRASITSV 831
A S P G+ + G +RAAL S A L R S SRAS+T
Sbjct: 517 RASPTWTPSTASPTGSPSTALAMGSPSRAALTRTPSRASLTRTPSRASLTTPSRASLTRT 576
Query: 832 TS 833
S
Sbjct: 577 PS 578
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 131 bits (329), Expect = 3e-30
Identities = 135/461 (29%), Positives = 177/461 (38%), Gaps = 77/461 (16%)
Query: 189 LPRPAP--SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA 246
LP P P A P PP P S ++S +A G R ++ SA
Sbjct: 11 LPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQINDRSA 70
Query: 247 TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP-RKDAAPALGPLSSSPLA 305
+ S + G+ + P L A P + P ++D A G P +
Sbjct: 71 PQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAG--GKTGQGPGS 128
Query: 306 -TPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ 364
PSP ++ + P +P T + APP P+ P P PP PP
Sbjct: 129 RAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPA-----PPPPTPPP-- 181
Query: 365 ATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS 424
P PPL P P P + P PL +PP P L +A P
Sbjct: 182 -----------------PPPPLPP---PLPSSSPIKT--PLVSPPGPLTKGNLPVVAPPV 219
Query: 425 PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA-PPSLAAPPLQVPP 483
P AP PPP PP PP PP+ P++ +A P LA PL +PP
Sbjct: 220 PCAP-------------PPPPPP-----PPPTPPPLPPASVLSDKAVKPQLA--PLHLPP 259
Query: 484 SPPASPPMSPSATPPPQAPPPLAAPPLQLAK----PPPQAPPALATPPLQALPSPPASFP 539
PP P + P P +A P A P Q A+ PPP PP + P +LP+PP P
Sbjct: 260 IPPPLPLLPPCGYPGLKAEP---ASPAQDAQEPPAPPPPLPPYASCSPRASLPAPP--LP 314
Query: 540 GQAPFSPSASLPMSPLATPPPQAPPVLA-APLLQVPPSPPASPTLQAPRRPPTPGPDTSV 598
G S S + P P +P QAPP A A L PP+PP S +R PG
Sbjct: 315 GVN--SSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGK 372
Query: 599 SGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTP 639
P PP PP+RSP++ LS + + T P
Sbjct: 373 LNP---------PPAPPARSPTTELSSKSQQATAWTPTQQP 404
Score = 105 bits (263), Expect = 1e-22
Identities = 141/472 (29%), Positives = 172/472 (36%), Gaps = 88/472 (18%)
Query: 17 PAARAPGLLTPRPP-GSPRPPPPVTPAA---LRVLGAAGAVGRKP-LAERAGGIGGATIP 71
P P L P PP G+P PPPP P L A GR LA+ G +
Sbjct: 4 PPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVT 63
Query: 72 ESAPRAGP--TRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129
+ R+ P S GT+ S A+ RG PP G G
Sbjct: 64 QINDRSAPQIESSKGTNKEGGGS---ANTRGASTPP--------------TLGDLFAG-- 104
Query: 130 GQKGLRISAEETVARGKATEAPKRSALSAGARRDT-SGPTPGTPSPAMARRSRAAG-TEV 187
G LR + + VA GK + P A S T SGP SP + S A G
Sbjct: 105 GFPVLRPAGQRDVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAART 164
Query: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247
PRP A P PPT P P P PS+ S T
Sbjct: 165 APPRPNVPA-PPPPTPPP-------------PPPPLPPPLPSS------------SPIKT 198
Query: 248 PLSSPARSGPSARG-----TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 302
PL SP GP +G P P P P P PP TPP A L +
Sbjct: 199 PLVSP--PGPLTKGNLPVVAPPVPCAPPPPPP-------PPPPTPPPLPPASVLSDKAVK 249
Query: 303 PLATPSPSAALQSQAPPTLPATPHSS--SLTCQLATPLPLAPPSPSAPPSLQTLPSPPAT 360
P P + PP LP P L + A+P A P+ PP P PP
Sbjct: 250 PQLAPLHLPPI----PPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPP-----PLPPYA 300
Query: 361 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA-LPPLQAPPSPPASPPLSP 419
S SL +P L +S +PP P +P QAPP A L APP+PP S P
Sbjct: 301 SCS-PRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPF-- 357
Query: 420 LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 471
L P A L +PPP+PP ++P + +S +A P+Q P
Sbjct: 358 LQKKRHGRPGAGGGKL-----NPPPAPPARSPTTELSSKSQQATAWTPTQQP 404
Score = 104 bits (259), Expect = 4e-22
Identities = 114/401 (28%), Positives = 146/401 (36%), Gaps = 101/401 (25%)
Query: 381 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ--- 437
+P PP P PPP PP L PP P +PP S S L P+ +AL + Q
Sbjct: 1 MPVPPPPPPPLPPP--PPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTR 58
Query: 438 ----------------------------APFSPPPSPPVQAPFSPPASPPVSPSAT---- 465
A +PP P + P+
Sbjct: 59 LRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVA 118
Query: 466 -------PPSQAP-PSLAAPPLQVPPSPPASPPMSPSA-------TPPPQAPPPLAAPPL 510
P S+AP P L + P PPASP + ++ T PP+ P PP
Sbjct: 119 GGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPT 178
Query: 511 QLAKPPPQAPPALATPPLQA-LPSPP-----ASFPGQAPFSPSASLPMSPLATPPPQAPP 564
PPP PP ++ P++ L SPP + P AP P A P P PPP PP
Sbjct: 179 PPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCA--PPPPPPPPPPTPPP 236
Query: 565 VLAAPL------------LQVPPSPPASPTLQAPRRPPT--PGPDTSVSGPRLTLALAPG 610
+ A + L +PP PP P L PP PG + P P
Sbjct: 237 LPPASVLSDKAVKPQLAPLHLPPIPPPLPLL-----PPCGYPGLKAEPASPAQDAQEPPA 291
Query: 611 PPPP----PSRSPSSTLSGPDLAGHSSSATS---TPEELRGYDSGPE-GGAAASPPPDAE 662
PPPP S SP ++L P L G +SS+ + P + + + P+ GA A P P
Sbjct: 292 PPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAP--- 348
Query: 663 LAACHPAAWSRGPAPPLAFRGAPGA------PLPWPPATGP 697
PA P G PGA P P PPA P
Sbjct: 349 -----PAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSP 384
Score = 72.4 bits (176), Expect = 2e-12
Identities = 116/440 (26%), Positives = 144/440 (32%), Gaps = 135/440 (30%)
Query: 3 NKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERA 62
+K + G +A T A P L G P + PA R + A G G+ P RA
Sbjct: 76 SKGTNKEGGGSANTRGASTPPTLGDLFAGGF---PVLRPAGQRDV-AGGKTGQGP-GSRA 130
Query: 63 GG-------IGGATIPESAPRAGPTRSAGTSSRNPASRP--PASGRGERAPPAKNTSPG- 112
I G IP ++PR G T A ++R RP PA PP P
Sbjct: 131 PSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPL 190
Query: 113 PVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP 172
P SSP + + PGPL + L + A P P P
Sbjct: 191 PSSSPIKTPLVSPPGPLTKGNLPVVAP---------------------------PVPCAP 223
Query: 173 SPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG 232
P P P P+ P PP +S +P A P
Sbjct: 224 PPPP-------------PPPPPTPPPLPP--------ASVLSDKAVKPQLAPLHLPPIPP 262
Query: 233 GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA 292
L PL P P + P +PA +Q P PP PP
Sbjct: 263 PL-------------PLLPPC-GYPGLKAEPASPAQDAQEPP------APPPPLPP---- 298
Query: 293 APALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPS--APP- 349
A+ SP A+L + P LP SS TP PL P SPS APP
Sbjct: 299 -----------YASCSPRASLPA---PPLPGVNSSSE------TPPPLPPKSPSFQAPPQ 338
Query: 350 --SLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQA 407
Q LP+PPA P SQ P P L
Sbjct: 339 KAGAQALPAPPAPPGSQ-----------------------PFLQKKRHGRPGAGGGKLNP 375
Query: 408 PPSPPASPPLSPLATPSPQA 427
PP+PPA P + L++ S QA
Sbjct: 376 PPAPPARSPTTELSSKSQQA 395
Score = 62.4 bits (150), Expect = 2e-09
Identities = 106/416 (25%), Positives = 138/416 (33%), Gaps = 131/416 (31%)
Query: 474 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL---------- 523
+ PP PP PP PP+ PPP A PP++ L + P+ AL
Sbjct: 1 MPVPPPPPPPLPPPPPPLGAPPPPPPSA-PPVSTDTSSLRRADPKGRSALLADIQQGTRL 59
Query: 524 ---------ATPPLQA----------------LPSPP-------ASFP------------ 539
+ P +++ +PP FP
Sbjct: 60 RKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAG 119
Query: 540 ---GQAPFS--PSASLPMSPLATP--PPQAPPV-----------LAAPLLQVPPSPPASP 581
GQ P S PS LP ++ P PP +P + A P VP PP +P
Sbjct: 120 GKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTP 179
Query: 582 TLQAPRRPP--------------TPGPDTS----VSGPRLTLALAPGPPPPPSR----SP 619
P PP PGP T V P + A P PPPPP P
Sbjct: 180 PPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPP 239
Query: 620 SSTLSG----PDLAGHSSSATSTPEEL------RGYDSGPEGGA------AASPPPDAEL 663
+S LS P LA P L G + P A A PPP
Sbjct: 240 ASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPY 299
Query: 664 AACHPAAWSRGPAPPL-AFRGAPGAPLPWPPAT----GPGSADGLCTIYETEGPESATP- 717
A+C P A PAPPL + P P PP + P G + P + P
Sbjct: 300 ASCSPRA--SLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPF 357
Query: 718 -------APGA----LDPGPS-PGTSGGKAAAGAGAGASSRSPKQARLGELPLGAL 761
PGA L+P P+ P S + A++ +P Q G+L G+L
Sbjct: 358 LQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQATAWTPTQQPGGQLRNGSL 413
>gi|239508790 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 490
Score = 130 bits (327), Expect = 5e-30
Identities = 141/471 (29%), Positives = 190/471 (40%), Gaps = 74/471 (15%)
Query: 265 APAHPSQPKPKGLQALRPPQVTP------PRKDAAPALGPLSSS-PLATP-----SPSAA 312
+P P P L +L P V+P P P+S PL +P SP +
Sbjct: 18 SPHCPLVPPHHPLVSLHHPLVSPHFPLVSPHHPLVSLHHPVSPHFPLVSPHHPLMSPHYS 77
Query: 313 LQSQAPPTLPATPHSSSLTCQLATP--LPLAPPSPSAPPSLQTLPSPPATPPSQATTSLG 370
L S P P +PH C L +P ++P P P L +PSPP+ PS
Sbjct: 78 LVS--PQYSPVSPH-----CPLVSPHYSLVSPHRPLVSPLLSGVPSPPSDVPSLL----- 125
Query: 371 SPTLQATHSFLPSPPLSPLATPPPQAPPALALPP--LQAPPSPPASPPLSPLATPSPQAP 428
S +PS P S +++PP P L+ P L PSPP+ P P PSP +
Sbjct: 126 --------SGVPSLP-SDVSSPPSDVPSLLSDVPSLLSGVPSPPSDVPSPPSDVPSPPSD 176
Query: 429 NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP--PSLAAPPLQVPPSPP 486
+ + +P S PSPP P P P +S +PPS P + +PP VP P
Sbjct: 177 VPSLLSGVPSPPSDVPSPPSDVPSPPSDVPLLSDVPSPPSDVPLLSDVPSPPSDVPSLPS 236
Query: 487 ASPPMSPSATPPPQAPPPLA---APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP 543
P +S +PP P L+ +PP ++ PP P L+ P +LPS S P
Sbjct: 237 DVPSLSGVPSPPSDVPSLLSGVPSPPSDIS-PPSDVPSLLSDVP--SLPSDVPSLLSGVP 293
Query: 544 FSPSASLP--MSPLATPPPQAP-PVLAAPLLQVPPSPPA---SPTLQAPRRPPTPGPDTS 597
SP + +P +S + +PP P P PLL PSPP+ SP P P +
Sbjct: 294 -SPPSDVPSLLSDVPSPPSDVPSPPSDIPLLSGVPSPPSDVPSPPSDVPSPPSDVPLLSG 352
Query: 598 VSGPRLTLALAPGPPPPPSRSPSSTLS------------GPDLAGHSSSATSTPEELRGY 645
V P + L G P PPS PS +S P S + P L G
Sbjct: 353 VPSPLSDVPLLSGVPSPPSDVPSLLMSPHRLLMSHYSLVSPHRLDVPSLLSDVPSLLSGV 412
Query: 646 DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLP-WPPAT 695
S P G S P + + P+ S P+P G P+ W P T
Sbjct: 413 PSSPSG--VPSLPSGVPILSGVPSLPSGVPSP-------SGVPITLWCPLT 454
Score = 100 bits (248), Expect = 7e-21
Identities = 110/366 (30%), Positives = 143/366 (39%), Gaps = 48/366 (13%)
Query: 376 ATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASP--PLSPLATP-SPQAPNALA 432
+TH + SP PL PP P PL +P P SP PL L P SP P
Sbjct: 11 STHYSVVSPHC-PLV--PPHHPLVSLHHPLVSPHFPLVSPHHPLVSLHHPVSPHFPLVSP 67
Query: 433 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 492
H L +P SP +P SP P VSP + S P L +P L PSPP+ P
Sbjct: 68 HHPLMSPHYSLVSPQY-SPVSPHC-PLVSPHYSLVSPHRP-LVSPLLSGVPSPPSDVPSL 124
Query: 493 PSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPP--LQALPSPPASFPGQAPFSPSASL 550
S P + P ++ PP P L+ P L +PSPP+ P
Sbjct: 125 LSGVP---------SLPSDVSSPPSDVPSLLSDVPSLLSGVPSPPSDVPS---------- 165
Query: 551 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 610
P S + +PP P +L+ + PPS SP P P + V P + L
Sbjct: 166 PPSDVPSPPSDVPSLLSG--VPSPPSDVPSPPSDVPSPPSDVPLLSDVPSPPSDVPLLSD 223
Query: 611 PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDA--------E 662
P PPS PS P L+G S + P L G S P SPP D
Sbjct: 224 VPSPPSDVPSLPSDVPSLSGVPSPPSDVPSLLSGVPSPPSD---ISPPSDVPSLLSDVPS 280
Query: 663 LAACHPAAWSRGPAPPLAFRGAPG--APLPWPPATGPGSADGLCTIYETEGPESATPAPG 720
L + P+ S P+PP P + +P PP+ P + + P S P+P
Sbjct: 281 LPSDVPSLLSGVPSPP---SDVPSLLSDVPSPPSDVPSPPSDIPLLSGVPSPPSDVPSPP 337
Query: 721 ALDPGP 726
+ P P
Sbjct: 338 SDVPSP 343
Score = 92.0 bits (227), Expect = 2e-18
Identities = 105/366 (28%), Positives = 136/366 (37%), Gaps = 57/366 (15%)
Query: 241 SLSSSATPLSSPARSG--------PSA-RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKD 291
SL S PL SP SG PS G P P+ S P P V D
Sbjct: 98 SLVSPHRPLVSPLLSGVPSPPSDVPSLLSGVPSLPSDVSSP---------PSDVPSLLSD 148
Query: 292 AAPALGPLSSSPLATPSPSAALQSQ------------APPTLPATPHSSSLTCQLATPLP 339
L + S P PSP + + S +PP+ +P S + PL
Sbjct: 149 VPSLLSGVPSPPSDVPSPPSDVPSPPSDVPSLLSGVPSPPSDVPSPPSDVPSPPSDVPLL 208
Query: 340 LAPPSP-SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP------LSPLATP 392
PSP S P L +PSPP+ PS P+ + S +PSPP LS + +P
Sbjct: 209 SDVPSPPSDVPLLSDVPSPPSDVPS-------LPSDVPSLSGVPSPPSDVPSLLSGVPSP 261
Query: 393 PPQAPPALALPPLQAP-PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 451
P P +P L + PS P+ P PSP + + + +P S PSPP P
Sbjct: 262 PSDISPPSDVPSLLSDVPSLPSDVPSLLSGVPSPPSDVPSLLSDVPSPPSDVPSPPSDIP 321
Query: 452 FSPPASPPVSPSATPPSQAP-PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP- 509
P S +PPS P P P L PSP + P+ PP P L P
Sbjct: 322 LLSGVPSPPSDVPSPPSDVPSPPSDVPLLSGVPSPLSDVPLLSGVPSPPSDVPSLLMSPH 381
Query: 510 ------LQLAKPPPQAPPALATPP---LQALPSPPASFPGQAPFSPSAS-LPMSPLATPP 559
L P P+L + L +PS P+ P P S +P P P
Sbjct: 382 RLLMSHYSLVSPHRLDVPSLLSDVPSLLSGVPSSPSGVPSLPSGVPILSGVPSLPSGVPS 441
Query: 560 PQAPPV 565
P P+
Sbjct: 442 PSGVPI 447
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 130 bits (326), Expect = 7e-30
Identities = 208/756 (27%), Positives = 255/756 (33%), Gaps = 147/756 (19%)
Query: 22 PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGI-----GGATIPESAPR 76
PGL P PP P PPPP P G P G+ G A PE
Sbjct: 242 PGLPLPPPPLPPPPPPPPPPPP----PLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGS 297
Query: 77 AGPTRSAGTSSRN-----PASRPPASGRGERAPPAKNTSPGP----VSSPGRASGTTRPG 127
A P R S PA A G R PA PGP S G T PG
Sbjct: 298 APPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPG 357
Query: 128 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT--PGTPSPAMARRSRAAGT 185
LR E V R + + +A +A S P PGT + + + S G
Sbjct: 358 ----SDLR---ESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGL 410
Query: 186 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS 245
P P P + + S H PS + R+P G + +
Sbjct: 411 RGVEPNPGI-----PGADHYQTPALEVSHHGRLGPSAHSSRKPFLG-----------APA 454
Query: 246 ATP-LSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL 304
ATP LS P GPS+ P P P P L+ P R+D L L
Sbjct: 455 ATPHLSLPP--GPSSPPPPPCPRLLRPPPPPAW--LKGPACRAAREDGE-ILEELFFGTE 509
Query: 305 ATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ 364
P P APP LP H L PP+ Q +PP TPP+
Sbjct: 510 GPPRP-------APPPLP---HREGF---------LGPPASRFSVGTQDSHTPP-TPPTP 549
Query: 365 ATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA--LPPLQAPPSP---PASPPLSP 419
T+S S + +HS S P P++ PPP P LA + PL PPSP P PPL P
Sbjct: 550 TTSSSNSNS--GSHS---SSPAGPVSFPPP---PYLARSIDPLPRPPSPAQNPQDPPLVP 601
Query: 420 LATPSPQAPNALAVHLLQAPFSPP--PSPPVQAPFSPPASP--PVSPSATPPSQAPPSLA 475
L P AP + F P P P V P +P P P P + P PP +
Sbjct: 602 LTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVG 661
Query: 476 APPLQVP---PSPPASPPMSPSATPPPQ---APPPLAAPPLQL----AKPPPQAPPALAT 525
P + P PP P+ P + P LA L K Q
Sbjct: 662 ELPARGPRLFDFPPT--PLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGV 719
Query: 526 PPLQALPSPPASFPGQAPF----SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP 581
P L P AS Q+PF +P+ + P + T A + P P P
Sbjct: 720 APQPPLKEPFASL--QSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPP 777
Query: 582 TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS-----RSPSSTLSGPDLA----GHS 632
+ PP P P PPPPPS +S +S L G G +
Sbjct: 778 PPPLAKFPPPSQPQ-------------PPPPPPPSPASLLKSLASVLEGQKYCYRGTGAA 824
Query: 633 SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWP 692
S P Y GP GA A PP A AP A G+P P
Sbjct: 825 VSTRPGPLPTTQYSPGPPSGATALPPTSA--------------AP-----SAQGSPQPSA 865
Query: 693 PATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 728
++ S G E E P PG + P P
Sbjct: 866 SSSSQFSTSGGPWARERRAGEE--PVPGPMTPTQPP 899
Score = 91.7 bits (226), Expect = 3e-18
Identities = 193/751 (25%), Positives = 241/751 (32%), Gaps = 151/751 (20%)
Query: 11 GAAARTP-AARAPGLLTPRPPGSP---RPPPPVTPAALRVLGAAGAVGRKP---LAERAG 63
GA A TP + PG +P PP P RPPPP PA L+ G A R+ L E
Sbjct: 451 GAPAATPHLSLPPGPSSPPPPPCPRLLRPPPP--PAWLK--GPACRAAREDGEILEELFF 506
Query: 64 GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGT 123
G G P AP P R PASR + PP T P P +S ++
Sbjct: 507 GTEGP--PRPAPPPLPHREGFLGP--PASRFSVGTQDSHTPP---TPPTPTTSSSNSNS- 558
Query: 124 TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA 183
G + +P +GP P P +AR
Sbjct: 559 ---------------------GSHSSSP-------------AGPVSFPPPPYLARSIDP- 583
Query: 184 GTEVGLPR-PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242
LPR P+P+ P+ P P P+P + + G +RP S
Sbjct: 584 -----LPRPPSPAQNPQDPPLVPLT--------LALPPAPPSSCHQNTSGSFRRPES--- 627
Query: 243 SSSATPLSSPARSGPSAR-GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP--- 298
P R P+ P P P L + PQ PP PA GP
Sbjct: 628 --------------PRPRVSFPKTPEVGPGPPPGPLS--KAPQPVPPGVGELPARGPRLF 671
Query: 299 -LSSSPL-----------ATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPS 346
+PL P A + ++ +A PL P S
Sbjct: 672 DFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFAS 731
Query: 347 APPSLQTLPSPPATPPSQA--TTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP 404
T +P T P+ A TT+ + T AT P P A PPP PP PP
Sbjct: 732 LQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKP---PPALPPP--PPLAKFPP 786
Query: 405 ---LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 461
Q PP PP SP + S A S P P +SP PP
Sbjct: 787 PSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSP--GPPSG 844
Query: 462 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA-PPLQLAKPPPQAP 520
+A PP+ AAP Q P P AS S + P A A P+ P Q P
Sbjct: 845 ATALPPTS-----AAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPP 899
Query: 521 PALATPPLQALPSPPASFPGQAP-----FSPSASLPMSPLAT------------PPPQAP 563
P L+ PP ++ SA+ P P+ T PP QA
Sbjct: 900 PPLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAK 959
Query: 564 PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL 623
Q R SV G R A P L
Sbjct: 960 EEAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSV-GRRPREGRAKAKAKVPKEKSRRVL 1018
Query: 624 SGPDLAGHSSSATSTPEELRGYD-SGPE-GGAAASPPPDAELAACHPAAWSRGPAPPLAF 681
DL EE++G + S P+ GGA+ + PP A PA S P PP A
Sbjct: 1019 GNLDLQS---------EEIQGREKSRPDLGGASKAKPPTAPAPPSAPAP-SAQPTPPSAS 1068
Query: 682 RGAPGAPLPWPPATGPGSADGLCTIYETEGP 712
A P G AD L +EGP
Sbjct: 1069 VPGKKAREEAPGPPGVSRADMLKLRSLSEGP 1099
Score = 89.7 bits (221), Expect = 1e-17
Identities = 136/497 (27%), Positives = 169/497 (34%), Gaps = 98/497 (19%)
Query: 342 PPSPSA--PPSLQTLPSPPAT---PPSQATTSLGSPTLQATHSFLPS-PPLSPLATPPPQ 395
PP A PP +Q P PPA P + S G + +S PP PL PPP
Sbjct: 195 PPVKRAAEPPVVQ--PVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPL--PPPP 250
Query: 396 APPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP 455
PP PP PP PP PPL LAT SP P L L + P + +PP
Sbjct: 251 LPP----PP---PPPPPPPPPLPGLAT-SP--PFQLTKPGLWSTLHGDAWGPERKGSAPP 300
Query: 456 ASPPVSPSATP--PSQAPPSLAAPP--LQVPPSPPASPPMSPSATP----PPQAPP--PL 505
S P AP A PP VP +PP P P A P PP L
Sbjct: 301 ERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPGSDL 360
Query: 506 AAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL--ATPPPQAP 563
+Q ++ PA T + PS P PG S S+S + L P P P
Sbjct: 361 RESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIP 420
Query: 564 ---------------------------PVLAAPL----LQVPPSPPASPTLQAPRRPPTP 592
P L AP L +PP P + P PR P
Sbjct: 421 GADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPP 480
Query: 593 GPDTSVSGPRLTLAL-----------------APGPPPPPSRS-----PSSTLSGPDLAG 630
P + GP A P PPP P R P+S S
Sbjct: 481 PPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDS 540
Query: 631 HS-----SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAP 685
H+ + TS+ G S G + PPP + P R P+P + P
Sbjct: 541 HTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPL--PRPPSPAQNPQDPP 598
Query: 686 GAPL-----PWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAG 740
PL P PP++ + G E+ P + P + PGP PG KA
Sbjct: 599 LVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPL-SKAPQPVP 657
Query: 741 AGASSRSPKQARLGELP 757
G + RL + P
Sbjct: 658 PGVGELPARGPRLFDFP 674
Score = 52.0 bits (123), Expect = 2e-06
Identities = 92/361 (25%), Positives = 131/361 (36%), Gaps = 55/361 (15%)
Query: 22 PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAV--GRKPLAERAGGIGGATIPESAPRA-- 77
P L PP P+PPPP P+ +L + +V G+K R G +T P P
Sbjct: 779 PPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQK-YCYRGTGAAVSTRPGPLPTTQY 837
Query: 78 GPTRSAGTSSRNPASRPPASGRGERAPPAKN-----TSPGPVSSPGRASGTTRPGPLG-- 130
P +G ++ P S P S +G P A + TS GP + RA PGP+
Sbjct: 838 SPGPPSGATALPPTSAAP-SAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPT 896
Query: 131 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP 190
Q +S + + E R+ + R S P P V
Sbjct: 897 QPPPPLSLPPARSESEVLEEISRACETLVERVGRSATDPADP--------------VDTA 942
Query: 191 RPAPSARPR--PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248
PA S R PP + ++ A+ S + +RR R R+ S
Sbjct: 943 EPADSGTERLLPPAQAKEEAGGVAAV------SGSCKRRQKEHQKEHRRHRRACKDS--- 993
Query: 249 LSSPARSGPSARGTPRAPAHPSQPKPKGLQALR----PPQVTPPRKDAAPALGPLSSS-P 303
+ R G RA A PK K + L + R+ + P LG S + P
Sbjct: 994 VGRRPREG-------RAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSRPDLGGASKAKP 1046
Query: 304 LATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPS 363
P+P +A A PT P S+S+ + A PP S L+ L S PP
Sbjct: 1047 PTAPAPPSAPAPSAQPT----PPSASVPGKKAREEAPGPPGVSRADMLK-LRSLSEGPPK 1101
Query: 364 Q 364
+
Sbjct: 1102 E 1102
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 128 bits (322), Expect = 2e-29
Identities = 227/880 (25%), Positives = 283/880 (32%), Gaps = 133/880 (15%)
Query: 3 NKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERA 62
++ DK + GA PG TP PG P PP P P L AA G E+A
Sbjct: 136 DRGDKGEKGAPGPRGRDGEPG--TPGNPGPPGPPGPPGPPGLGGNFAAQMAGG--FDEKA 191
Query: 63 GG------------IGGATIPESAPRAGPTRSAGTSSR--NPASRPPASGRGERAPPAKN 108
GG +G P A GP G P P RG PP K
Sbjct: 192 GGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKP 251
Query: 109 TSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARG----KATEAPKRSALSAGARRDT 164
G PG+A PGP G +G + +G + K A + G + ++
Sbjct: 252 GDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGES 311
Query: 165 SGP-TPGTPSPAMAR-----RSR-----AAGTEVGLPRPAPSARPRP--PTEGPRKSVSS 211
P G+P P R R R AAG +P P+ P P P GP
Sbjct: 312 GSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPG---FP 368
Query: 212 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ 271
+ + E P R P G Q P + +P + A P G P A
Sbjct: 369 GAPGAKGEAGPTGARGPE---GAQGPRGEP-GTPGSPGPAGASGNPGTDGIPGAKGSAGA 424
Query: 272 PKPKGLQALRPPQVTPPRKDAAPALGPLSSS-------------PLATPSPSAALQSQAP 318
P G P+ P + A LGP + P P P+ Q
Sbjct: 425 PGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAG---PQGA 481
Query: 319 PTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLP------SPPATPPSQATTSLGSP 372
P + P+ PP P + P P P + + L P
Sbjct: 482 PGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGP 541
Query: 373 TLQATHSFLPSPPLSP----LATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQ-A 427
P P P L P A P + P AP P P PQ A
Sbjct: 542 KGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGP------PGPQGA 595
Query: 428 PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA 487
V P P P +P + P A PP P+ PA
Sbjct: 596 RGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGL--RGLPGKDGETGAAGPP---GPAGPA 650
Query: 488 SPPMSPSATPPP--QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS 545
A P Q P PP + KP Q P A P P FPG+ S
Sbjct: 651 GERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERG-S 709
Query: 546 PSA-------SLPMSPLATPP-----PQAPP-VLAAPLLQVPPSPPASPTLQAPR----- 587
P A LP +P P P PP P LQ P + + P+
Sbjct: 710 PGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD 769
Query: 588 ---RPP--TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL 642
+ P PG D G LT + GPP P + GP S+ A P E
Sbjct: 770 VGEKGPEGAPGKD---GGRGLTGPI--GPPGPAGANGEKGEVGPPGPAGSAGARGAPGE- 823
Query: 643 RGYDSGPEGGAAASPPPDAE----LAACHPAAWSRGPAPPLAFRGAPGAPLPWPP--ATG 696
RG ++GP G A + PP A+ A +G A +G GAP P P TG
Sbjct: 824 RG-ETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTG 882
Query: 697 PGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGEL 756
P A G +GP AT PGA PG++G G + PK AR
Sbjct: 883 PKGARG------AQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSG 936
Query: 757 PLGALQASVVQHLLSRTLLLAAAEGAAGGSG-GGPGGAEG 795
P G +Q A G G G GP GAEG
Sbjct: 937 PPGRAGEPGLQG-------PAGPPGEKGEPGDDGPSGAEG 969
Score = 119 bits (298), Expect = 1e-26
Identities = 207/818 (25%), Positives = 246/818 (30%), Gaps = 131/818 (16%)
Query: 11 GAAART-PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG--G 67
G RT PA A PG PP PV PA G GA G K A G G G
Sbjct: 330 GERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGP--GFPGAPGAKGEAGPTGARGPEG 387
Query: 68 ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG---PVSSPGRASGTT 124
A P P + +S NP + +G P +PG P PG T
Sbjct: 388 AQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGAT- 446
Query: 125 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184
GPLG KG + E +A K + PK AG + G P PA R A
Sbjct: 447 --GPLGPKGQ--TGEPGIAGFKGEQGPKGEPGPAGPQ--------GAPGPAGEEGKRGAR 494
Query: 185 TEVGLPRPA--PSARPRPPTEG-PRKSVSSASEHSTTEPSPAARRRPS-AGGGLQRPASR 240
E G P P R P G P + + + + E P+ P A G RP
Sbjct: 495 GEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEP 554
Query: 241 SLSSSATPLSSPARSGPSAR-GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPL 299
L + P +GP + G AP +P P G Q R P +
Sbjct: 555 GLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGAR----------GQPGVMGF 604
Query: 300 SSSPLATPSPSAALQSQAP--PTLPATPHSSSLTCQLATPLPLAPPSPSA------PPSL 351
A P A + P P L P T P P P P
Sbjct: 605 PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 664
Query: 352 QTLPSPPATPPSQATTSLGSPTLQATHSFLPSP----PLSPLATPPPQAPPALALPPLQA 407
Q LP PP PP + G P Q +P P P + P LQ
Sbjct: 665 QGLPGPPG-PPGEG----GKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQ--GLQG 717
Query: 408 PPSPPASPPLS-------PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 460
P P +P P P Q P L P A + P
Sbjct: 718 PRGLPGTPGTDGPKGASGPAGPPGAQGPPGL---------QGMPGERGAAGIAGPKGDRG 768
Query: 461 SPSATPPSQAPPSLAAPPLQVPPSPP----ASPPMSPSATPPPQAPPPLAAPPLQLAKPP 516
P AP L P PP A+ P P P + +
Sbjct: 769 DVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETG 828
Query: 517 PQAPPALATPPLQALPSPPASFPGQAPFSPSASLP--MSPLATPPPQAPPVLAAPL---- 570
P P A PP G+A A P P P PQ P + P
Sbjct: 829 PPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARG 888
Query: 571 LQVPPS------------PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 618
Q PP PP S P PP P G R G PP R+
Sbjct: 889 AQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGAR-------GDSGPPGRA 941
Query: 619 PSSTLSGP-----------DLAGHSSSATSTPEELRGYDS-----GPEG--GAAASPPPD 660
L GP D + P+ L G G G G P P
Sbjct: 942 GEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPS 1001
Query: 661 AELA--ACHPAAWSRGPAPPLAFRGAPGAPLPW--------PPATGPGSADGLCTIYETE 710
E A+ RGP P+ G PG P P A GP DG +
Sbjct: 1002 GEPGKQGAPGASGDRGPPGPV---GPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDR 1058
Query: 711 GPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP 748
G A APGA P SPG +G G A ++ P
Sbjct: 1059 GETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGP 1096
Score = 100 bits (250), Expect = 4e-21
Identities = 204/860 (23%), Positives = 250/860 (29%), Gaps = 154/860 (17%)
Query: 11 GAAARTPAARAPGLLTPR-PPGSPRPPPPV----TPAALRVLGAAGAVGRKPLAERAGGI 65
G A T A G PR PG+P P P P + GA G+ G +A G
Sbjct: 375 GEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFP 434
Query: 66 GGATIPESAPRAGPTRSAGTSSRNPAS--RPPASGRGERAPPAKNTSPGPVSSPGRASGT 123
G P GP G + + + +GE P +PGP G+
Sbjct: 435 GPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGAR 494
Query: 124 TRPG---PLGQKGLR-------ISAEETVARGKATEAPKRSALSAGARRDTSGP-TPGTP 172
PG P+G G R ++ +A K + + AG + P PG P
Sbjct: 495 GEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEP 554
Query: 173 SPAMAR----RSRAAGTE--VGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 226
AR R AG + VG P AP RP GP+ + P A
Sbjct: 555 GLPGARGLTGRPGDAGPQGKVG-PSGAPGEDGRPGPPGPQGARGQPGVMGFPGPK-GANG 612
Query: 227 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS-------QPKPKGLQA 279
P G P + L P + G + P PA P+ P P G Q
Sbjct: 613 EPGKAGEKGLPGAPGLRGL------PGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQG 666
Query: 280 LRPPQVTP-----------PRKDAAPAL-GPLSSSPLATPSPSAALQS-QAPPTLPATPH 326
L P P P + AP L GP S Q Q P LP TP
Sbjct: 667 LPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPG 726
Query: 327 SSSLTCQLATPLPLAPPSPSAPPSLQTLPSP----------------------------- 357
+ P PP PP LQ +P
Sbjct: 727 TDG---PKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDG 783
Query: 358 ------PATPPSQATTS-----LGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 406
P PP A + +G P + +P PP P A PP
Sbjct: 784 GRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPP--GPAGFAGPP-G 840
Query: 407 APPSPPASP---------------PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 451
A P A P P P PQ P + PP A
Sbjct: 841 ADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPG----AT 896
Query: 452 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 511
P A+ V P + + PP P + P P P P A PP +
Sbjct: 897 GFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGP-AGPPGE 955
Query: 512 LAKPPPQAPPALATPP-LQALPSPPA--SFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 568
+P P PP Q L PGQ LP P P Q P +
Sbjct: 956 KGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLP-GPSGEPGKQGAPGASG 1014
Query: 569 PLLQVPPSPPASPTLQAPRRPP----TPGPD--------TSVSGPRLTLAL-----APGP 611
+ PP P P L P P +PG D V G R APGP
Sbjct: 1015 D--RGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGP 1072
Query: 612 PPPPSRSPSSTLSGP--DLAGHSSSATSTPEELRGYDS--GPEGGAAASPPPDAELAACH 667
P P + + G + S P RG GP G + P H
Sbjct: 1073 PGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGH 1132
Query: 668 PAAWSR----GPAPPLAFRGA-----PGAPLPWPPATGPGSADGLCTIYETEGPESATPA 718
GP P +GA P P P GP DG I GP
Sbjct: 1133 RGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGR 1192
Query: 719 PGALDPGPSPGTSGGKAAAG 738
G P PG G G
Sbjct: 1193 SGETGPAGPPGNPGPPGPPG 1212
Score = 95.5 bits (236), Expect = 2e-19
Identities = 181/715 (25%), Positives = 214/715 (29%), Gaps = 115/715 (16%)
Query: 10 AGAAARTPAARAPGLL----TPRPPGSP----RPPPPVTPAALRVLGAAGAVGRKPLAER 61
AG A APG P PPG P +P P GA G VG P ER
Sbjct: 647 AGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEA---GAPGLVG--PRGER 701
Query: 62 AGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRAS 121
G G P + GP GT P + P G PP PG PG
Sbjct: 702 -GFPGERGSPGAQGLQGPRGLPGT----PGTDGPKGASGPAGPPGAQGPPGLQGMPGERG 756
Query: 122 GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR 181
GP G RG E A R +GP G P PA A +
Sbjct: 757 AAGIAGPKGD------------RGDVGEKGPEGAPGKDGGRGLTGPI-GPPGPAGANGEK 803
Query: 182 AAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 241
EVG P PA SA G R + E T P PA P G +P ++
Sbjct: 804 G---EVGPPGPAGSA-------GARGAPGERGE--TGPPGPAGFAGPPGADG--QPGAKG 849
Query: 242 LSSSATP---LSSPARSGPSARGTPRAPAHPSQPK-PKGLQALRPPQVT----------P 287
A +P GPS P+ P + PK +G Q PP T P
Sbjct: 850 EQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQG--PPGATGFPGAAGRVGP 907
Query: 288 PRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSA 347
P + P P P P A PP P L P P
Sbjct: 908 PGSNGNPG-PPGPPGPSGKDGPKGARGDSGPPGRAGEP---GLQGPAGPPGEKGEPGDDG 963
Query: 348 PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA-----PPALAL 402
P + P P + L + LP P P P A PP
Sbjct: 964 PSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVG 1023
Query: 403 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 462
PP P+ SP A P A V + + V AP +P PP SP
Sbjct: 1024 PPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGE-----TGAVGAPGAP--GPPGSP 1076
Query: 463 SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPA 522
P+ Q P P S P PQ P + +P +
Sbjct: 1077 GPAGPTGKQGDRGEAGAQGPMGP--SGPAGARGIQGPQGP---RGDKGEAGEPGERGLKG 1131
Query: 523 -LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV------LAAPLLQV-- 573
LQ LP PP Q P+ P P P P P + P+
Sbjct: 1132 HRGFTGLQGLPGPPGPSGDQGASGPAG--PSGPRGPPGPVGPSGKDGANGIPGPIGPPGP 1189
Query: 574 --------PPSPPASPTLQAPRRPPTPGPDTSV---SGPRLTLALAPGPPPPPSRSPSST 622
P PP +P P PP PG D S GPR GP P
Sbjct: 1190 RGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPR-----EKGPDPLQYMRADQA 1244
Query: 623 LSGPDLAGHSSSATSTPEELRGYDS---GPEGGAAASPPPDAELAACHPAAWSRG 674
G L H + +T + L PEG +L CHP W G
Sbjct: 1245 AGG--LRQHDAEVDATLKSLNNQIESIRSPEGSRKNPARTCRDLKLCHP-EWKSG 1296
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 128 bits (322), Expect = 2e-29
Identities = 227/880 (25%), Positives = 283/880 (32%), Gaps = 133/880 (15%)
Query: 3 NKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERA 62
++ DK + GA PG TP PG P PP P P L AA G E+A
Sbjct: 67 DRGDKGEKGAPGPRGRDGEPG--TPGNPGPPGPPGPPGPPGLGGNFAAQMAGG--FDEKA 122
Query: 63 GG------------IGGATIPESAPRAGPTRSAGTSSR--NPASRPPASGRGERAPPAKN 108
GG +G P A GP G P P RG PP K
Sbjct: 123 GGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKP 182
Query: 109 TSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARG----KATEAPKRSALSAGARRDT 164
G PG+A PGP G +G + +G + K A + G + ++
Sbjct: 183 GDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGES 242
Query: 165 SGP-TPGTPSPAMAR-----RSR-----AAGTEVGLPRPAPSARPRP--PTEGPRKSVSS 211
P G+P P R R R AAG +P P+ P P P GP
Sbjct: 243 GSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPG---FP 299
Query: 212 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ 271
+ + E P R P G Q P + +P + A P G P A
Sbjct: 300 GAPGAKGEAGPTGARGPE---GAQGPRGEP-GTPGSPGPAGASGNPGTDGIPGAKGSAGA 355
Query: 272 PKPKGLQALRPPQVTPPRKDAAPALGPLSSS-------------PLATPSPSAALQSQAP 318
P G P+ P + A LGP + P P P+ Q
Sbjct: 356 PGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAG---PQGA 412
Query: 319 PTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLP------SPPATPPSQATTSLGSP 372
P + P+ PP P + P P P + + L P
Sbjct: 413 PGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGP 472
Query: 373 TLQATHSFLPSPPLSP----LATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQ-A 427
P P P L P A P + P AP P P PQ A
Sbjct: 473 KGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGP------PGPQGA 526
Query: 428 PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA 487
V P P P +P + P A PP P+ PA
Sbjct: 527 RGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGL--RGLPGKDGETGAAGPP---GPAGPA 581
Query: 488 SPPMSPSATPPP--QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS 545
A P Q P PP + KP Q P A P P FPG+ S
Sbjct: 582 GERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERG-S 640
Query: 546 PSA-------SLPMSPLATPP-----PQAPP-VLAAPLLQVPPSPPASPTLQAPR----- 587
P A LP +P P P PP P LQ P + + P+
Sbjct: 641 PGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD 700
Query: 588 ---RPP--TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL 642
+ P PG D G LT + GPP P + GP S+ A P E
Sbjct: 701 VGEKGPEGAPGKD---GGRGLTGPI--GPPGPAGANGEKGEVGPPGPAGSAGARGAPGE- 754
Query: 643 RGYDSGPEGGAAASPPPDAE----LAACHPAAWSRGPAPPLAFRGAPGAPLPWPP--ATG 696
RG ++GP G A + PP A+ A +G A +G GAP P P TG
Sbjct: 755 RG-ETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTG 813
Query: 697 PGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGEL 756
P A G +GP AT PGA PG++G G + PK AR
Sbjct: 814 PKGARG------AQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSG 867
Query: 757 PLGALQASVVQHLLSRTLLLAAAEGAAGGSG-GGPGGAEG 795
P G +Q A G G G GP GAEG
Sbjct: 868 PPGRAGEPGLQG-------PAGPPGEKGEPGDDGPSGAEG 900
Score = 119 bits (298), Expect = 1e-26
Identities = 207/818 (25%), Positives = 246/818 (30%), Gaps = 131/818 (16%)
Query: 11 GAAART-PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG--G 67
G RT PA A PG PP PV PA G GA G K A G G G
Sbjct: 261 GERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGP--GFPGAPGAKGEAGPTGARGPEG 318
Query: 68 ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPG---PVSSPGRASGTT 124
A P P + +S NP + +G P +PG P PG T
Sbjct: 319 AQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGAT- 377
Query: 125 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184
GPLG KG + E +A K + PK AG + G P PA R A
Sbjct: 378 --GPLGPKGQ--TGEPGIAGFKGEQGPKGEPGPAGPQ--------GAPGPAGEEGKRGAR 425
Query: 185 TEVGLPRPA--PSARPRPPTEG-PRKSVSSASEHSTTEPSPAARRRPS-AGGGLQRPASR 240
E G P P R P G P + + + + E P+ P A G RP
Sbjct: 426 GEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEP 485
Query: 241 SLSSSATPLSSPARSGPSAR-GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPL 299
L + P +GP + G AP +P P G Q R P +
Sbjct: 486 GLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGAR----------GQPGVMGF 535
Query: 300 SSSPLATPSPSAALQSQAP--PTLPATPHSSSLTCQLATPLPLAPPSPSA------PPSL 351
A P A + P P L P T P P P P
Sbjct: 536 PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 595
Query: 352 QTLPSPPATPPSQATTSLGSPTLQATHSFLPSP----PLSPLATPPPQAPPALALPPLQA 407
Q LP PP PP + G P Q +P P P + P LQ
Sbjct: 596 QGLPGPPG-PPGEG----GKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQ--GLQG 648
Query: 408 PPSPPASPPLS-------PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 460
P P +P P P Q P L P A + P
Sbjct: 649 PRGLPGTPGTDGPKGASGPAGPPGAQGPPGL---------QGMPGERGAAGIAGPKGDRG 699
Query: 461 SPSATPPSQAPPSLAAPPLQVPPSPP----ASPPMSPSATPPPQAPPPLAAPPLQLAKPP 516
P AP L P PP A+ P P P + +
Sbjct: 700 DVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETG 759
Query: 517 PQAPPALATPPLQALPSPPASFPGQAPFSPSASLP--MSPLATPPPQAPPVLAAPL---- 570
P P A PP G+A A P P P PQ P + P
Sbjct: 760 PPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARG 819
Query: 571 LQVPPS------------PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 618
Q PP PP S P PP P G R G PP R+
Sbjct: 820 AQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGAR-------GDSGPPGRA 872
Query: 619 PSSTLSGP-----------DLAGHSSSATSTPEELRGYDS-----GPEG--GAAASPPPD 660
L GP D + P+ L G G G G P P
Sbjct: 873 GEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPS 932
Query: 661 AELA--ACHPAAWSRGPAPPLAFRGAPGAPLPW--------PPATGPGSADGLCTIYETE 710
E A+ RGP P+ G PG P P A GP DG +
Sbjct: 933 GEPGKQGAPGASGDRGPPGPV---GPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDR 989
Query: 711 GPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP 748
G A APGA P SPG +G G A ++ P
Sbjct: 990 GETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGP 1027
Score = 100 bits (250), Expect = 4e-21
Identities = 204/860 (23%), Positives = 250/860 (29%), Gaps = 154/860 (17%)
Query: 11 GAAARTPAARAPGLLTPR-PPGSPRPPPPV----TPAALRVLGAAGAVGRKPLAERAGGI 65
G A T A G PR PG+P P P P + GA G+ G +A G
Sbjct: 306 GEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFP 365
Query: 66 GGATIPESAPRAGPTRSAGTSSRNPAS--RPPASGRGERAPPAKNTSPGPVSSPGRASGT 123
G P GP G + + + +GE P +PGP G+
Sbjct: 366 GPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGAR 425
Query: 124 TRPG---PLGQKGLR-------ISAEETVARGKATEAPKRSALSAGARRDTSGP-TPGTP 172
PG P+G G R ++ +A K + + AG + P PG P
Sbjct: 426 GEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEP 485
Query: 173 SPAMAR----RSRAAGTE--VGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 226
AR R AG + VG P AP RP GP+ + P A
Sbjct: 486 GLPGARGLTGRPGDAGPQGKVG-PSGAPGEDGRPGPPGPQGARGQPGVMGFPGPK-GANG 543
Query: 227 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS-------QPKPKGLQA 279
P G P + L P + G + P PA P+ P P G Q
Sbjct: 544 EPGKAGEKGLPGAPGLRGL------PGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQG 597
Query: 280 LRPPQVTP-----------PRKDAAPAL-GPLSSSPLATPSPSAALQS-QAPPTLPATPH 326
L P P P + AP L GP S Q Q P LP TP
Sbjct: 598 LPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPG 657
Query: 327 SSSLTCQLATPLPLAPPSPSAPPSLQTLPSP----------------------------- 357
+ P PP PP LQ +P
Sbjct: 658 TDG---PKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDG 714
Query: 358 ------PATPPSQATTS-----LGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 406
P PP A + +G P + +P PP P A PP
Sbjct: 715 GRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPP--GPAGFAGPP-G 771
Query: 407 APPSPPASP---------------PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 451
A P A P P P PQ P + PP A
Sbjct: 772 ADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPG----AT 827
Query: 452 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 511
P A+ V P + + PP P + P P P P A PP +
Sbjct: 828 GFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGP-AGPPGE 886
Query: 512 LAKPPPQAPPALATPP-LQALPSPPA--SFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 568
+P P PP Q L PGQ LP P P Q P +
Sbjct: 887 KGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLP-GPSGEPGKQGAPGASG 945
Query: 569 PLLQVPPSPPASPTLQAPRRPP----TPGPD--------TSVSGPRLTLAL-----APGP 611
+ PP P P L P P +PG D V G R APGP
Sbjct: 946 D--RGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGP 1003
Query: 612 PPPPSRSPSSTLSGP--DLAGHSSSATSTPEELRGYDS--GPEGGAAASPPPDAELAACH 667
P P + + G + S P RG GP G + P H
Sbjct: 1004 PGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGH 1063
Query: 668 PAAWSR----GPAPPLAFRGA-----PGAPLPWPPATGPGSADGLCTIYETEGPESATPA 718
GP P +GA P P P GP DG I GP
Sbjct: 1064 RGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGR 1123
Query: 719 PGALDPGPSPGTSGGKAAAG 738
G P PG G G
Sbjct: 1124 SGETGPAGPPGNPGPPGPPG 1143
Score = 95.5 bits (236), Expect = 2e-19
Identities = 181/715 (25%), Positives = 214/715 (29%), Gaps = 115/715 (16%)
Query: 10 AGAAARTPAARAPGLL----TPRPPGSP----RPPPPVTPAALRVLGAAGAVGRKPLAER 61
AG A APG P PPG P +P P GA G VG P ER
Sbjct: 578 AGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEA---GAPGLVG--PRGER 632
Query: 62 AGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRAS 121
G G P + GP GT P + P G PP PG PG
Sbjct: 633 -GFPGERGSPGAQGLQGPRGLPGT----PGTDGPKGASGPAGPPGAQGPPGLQGMPGERG 687
Query: 122 GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR 181
GP G RG E A R +GP G P PA A +
Sbjct: 688 AAGIAGPKGD------------RGDVGEKGPEGAPGKDGGRGLTGPI-GPPGPAGANGEK 734
Query: 182 AAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 241
EVG P PA SA G R + E T P PA P G +P ++
Sbjct: 735 G---EVGPPGPAGSA-------GARGAPGERGE--TGPPGPAGFAGPPGADG--QPGAKG 780
Query: 242 LSSSATP---LSSPARSGPSARGTPRAPAHPSQPK-PKGLQALRPPQVT----------P 287
A +P GPS P+ P + PK +G Q PP T P
Sbjct: 781 EQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQG--PPGATGFPGAAGRVGP 838
Query: 288 PRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSA 347
P + P P P P A PP P L P P
Sbjct: 839 PGSNGNPG-PPGPPGPSGKDGPKGARGDSGPPGRAGEP---GLQGPAGPPGEKGEPGDDG 894
Query: 348 PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA-----PPALAL 402
P + P P + L + LP P P P A PP
Sbjct: 895 PSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVG 954
Query: 403 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 462
PP P+ SP A P A V + + V AP +P PP SP
Sbjct: 955 PPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGE-----TGAVGAPGAP--GPPGSP 1007
Query: 463 SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPA 522
P+ Q P P S P PQ P + +P +
Sbjct: 1008 GPAGPTGKQGDRGEAGAQGPMGP--SGPAGARGIQGPQGP---RGDKGEAGEPGERGLKG 1062
Query: 523 -LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV------LAAPLLQV-- 573
LQ LP PP Q P+ P P P P P + P+
Sbjct: 1063 HRGFTGLQGLPGPPGPSGDQGASGPAG--PSGPRGPPGPVGPSGKDGANGIPGPIGPPGP 1120
Query: 574 --------PPSPPASPTLQAPRRPPTPGPDTSV---SGPRLTLALAPGPPPPPSRSPSST 622
P PP +P P PP PG D S GPR GP P
Sbjct: 1121 RGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPR-----EKGPDPLQYMRADQA 1175
Query: 623 LSGPDLAGHSSSATSTPEELRGYDS---GPEGGAAASPPPDAELAACHPAAWSRG 674
G L H + +T + L PEG +L CHP W G
Sbjct: 1176 AGG--LRQHDAEVDATLKSLNNQIESIRSPEGSRKNPARTCRDLKLCHP-EWKSG 1227
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 126 bits (317), Expect = 7e-29
Identities = 159/565 (28%), Positives = 197/565 (34%), Gaps = 89/565 (15%)
Query: 250 SSPARSG-----PSARGTPRAPAHP----SQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300
+SP G P G P P P S P+ K + + PR+ +
Sbjct: 746 TSPTEEGGVLTLPPVDGLPGRPPCPPGAESGPQTKFCSEIS--LIVSPRRISVQLDSHQP 803
Query: 301 SSPLATPSPSAALQSQAPPTLPAT--PHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPP 358
+ ++ P P +L A P + PHS S Q + ++ SA + +PSPP
Sbjct: 804 TQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVS----SAFKNSCNIPSPP 859
Query: 359 ATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQA-----PPSPP- 412
P +++++S+ P L P PPL + P + PPLQ PP PP
Sbjct: 860 PLPCTESSSSM--PGLGMVPP--PPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPL 915
Query: 413 ---ASPPLSPL----ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT 465
PP PL P P P A P + P PP P PP+ +
Sbjct: 916 PGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGI 975
Query: 466 PPSQAPPSLAAPP------LQVPPSPP------ASPPMSPSATPPPQAPPPLAA------ 507
PP P PP +PP PP PP P A PP PPPL
Sbjct: 976 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP--PPPLPGAGIPPP 1033
Query: 508 PPLQLAK-PPPQAPPALATPPLQALPS----PPASFPGQAPFSPSASLPMSPLATPPP-- 560
PPL A PPP P PP LP PP PG A P LP + + PPP
Sbjct: 1034 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG-AGIPPPPPLPGAGIPPPPPLP 1092
Query: 561 --QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP------ 612
PP P + +PP PP P P PP PG P + P PP
Sbjct: 1093 GAGIPPPPPLPGVGIPPPPPL-PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGI 1151
Query: 613 PPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS 672
PPP P + + P + P G P PPP A P
Sbjct: 1152 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIP---- 1207
Query: 673 RGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGP-------ESATPAPGALDPG 725
P PPL G P P P PP PG+ + GP S P P
Sbjct: 1208 --PPPPLPGMGIP--PAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFL 1263
Query: 726 PSPGTSGGKAAAGAGAGASSRSPKQ 750
P P SG G G S KQ
Sbjct: 1264 PPPLPSG---LFGLGMNQDKGSRKQ 1285
Score = 119 bits (298), Expect = 1e-26
Identities = 131/440 (29%), Positives = 154/440 (35%), Gaps = 76/440 (17%)
Query: 169 PGTPSPAMARRSRAAGTEV--GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 226
P PS A+ + GTE+ P P P A PP P + P P
Sbjct: 889 PTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGIL---------PLP---- 935
Query: 227 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT 286
P G G+ P ++ P P P P A P P P + PP
Sbjct: 936 -PLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGA--GIPPP--- 989
Query: 287 PPRKDAA-PALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSP 345
PP A P PL + + P P PP LP +P PP P
Sbjct: 990 PPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG------------IPPPPPLP 1037
Query: 346 SA----PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA 401
A PP L PP PP + P P PPL PPP P
Sbjct: 1038 GAGIPPPPPLPGAGIPP--PPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1095
Query: 402 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 461
+PP PP P P P P P A PP PP+ PP PP+
Sbjct: 1096 IPP--PPPLPGVGIP------PPPPLPGA----------GIPPPPPLPGAGIPP-PPPLP 1136
Query: 462 PSATPPSQAPPSLAAPPLQVPPSPPAS---PPMSPSATPPPQAPPPLAAPPLQLAKPPPQ 518
+ PP P + PP PP P A PP P A PP PPPL + PPP
Sbjct: 1137 GAGIPPPPPLPRVGIPP--PPPLPGAGIPPPPPLPGAGIPP--PPPLPG----VGIPPPP 1188
Query: 519 APPALATPPLQALPS----PPASFPGQA-PFSPSASLPMSPLATPPPQAPPVLAAPLL-Q 572
P + PP LP PP PG P +P+ LP PPP PV PLL Q
Sbjct: 1189 PLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQ 1248
Query: 573 VPPSPPASPTLQAPRRPPTP 592
V S +P + PP P
Sbjct: 1249 VGSSTLPTPQVCGFLPPPLP 1268
Score = 98.6 bits (244), Expect = 2e-20
Identities = 104/375 (27%), Positives = 127/375 (33%), Gaps = 53/375 (14%)
Query: 389 LATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP----FSPPP 444
+ T P + L LPP+ P PP P A PQ + L+ +P
Sbjct: 744 IQTSPTEEGGVLTLPPVDG---LPGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDS 800
Query: 445 SPPVQAPFSPPASPPV--SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 502
P Q+ PP P + S P PP + Q S S P +P
Sbjct: 801 HQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIP--SP 858
Query: 503 PPL-------AAPPLQLAKPPPQAPPALATP--PLQALPSPP-----ASFPGQAPFSPSA 548
PPL + P L + PPP P + P P A+P PP P P P A
Sbjct: 859 PPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGA 918
Query: 549 SLPMSPLATPPPQAPPVLAAPLLQVP----PSPPASPTLQAPRRPPTPGPDTSVSGPRLT 604
+P PPP P PL +P P PP P P PP PG + P
Sbjct: 919 GIP------PPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPG 972
Query: 605 LALAPGPP------PPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP 658
+ P PP PPP P + + P + P G P A PP
Sbjct: 973 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1032
Query: 659 PDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPA 718
P A P P PPL PGA +P PP PG+ G P
Sbjct: 1033 PPPLPGAGIP------PPPPL-----PGAGIP-PPPPLPGAGIPPPPPLPGAGIPPPPPL 1080
Query: 719 PGALDPGPSPGTSGG 733
PGA P P P G
Sbjct: 1081 PGAGIPPPPPLPGAG 1095
Score = 89.7 bits (221), Expect = 1e-17
Identities = 122/454 (26%), Positives = 146/454 (32%), Gaps = 99/454 (21%)
Query: 12 AAARTPAARAPGLLTPRPP---GSPRPPPPVTPAA----LRVLGAAGAVGRKPLAERAGG 64
A + P + +L P PP G+ PPPP P A L L AG PL
Sbjct: 895 AIPQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLP----- 949
Query: 65 IGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTT 124
GA IP P G AG PP G G PP + P P +G
Sbjct: 950 --GAAIPPPPPLPG----AGI-----PLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP 998
Query: 125 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 184
P PL G+ P AG P G P P G
Sbjct: 999 PPPPLPGAGI---------------PPPPPLPGAGIPPPPPLPGAGIPPP-----PPLPG 1038
Query: 185 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 244
+ P P P A PP P + P P P G G+ P +
Sbjct: 1039 AGIPPPPPLPGAGIPPPPPLPGAGI---------PPPP-----PLPGAGIPPPPPLPGAG 1084
Query: 245 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA-PALGPLSSSP 303
P P P P P P P + PP PP A P PL +
Sbjct: 1085 IPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGA--GIPPP---PPLPGAGIPPPPPLPGAG 1139
Query: 304 LATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSA----PPSLQTLPSPPA 359
+ P P + PP LP +P PP P A PP L + PP
Sbjct: 1140 IPPPPPLPRVGIPPPPPLP------------GAGIPPPPPLPGAGIPPPPPLPGVGIPPP 1187
Query: 360 TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS----- 414
P +G P P PPL PPP P + +PP APP PP
Sbjct: 1188 PP----LPGVGIP---------PPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPP 1234
Query: 415 PPLSPLATPS--PQAPNALAVHLLQAPFSPPPSP 446
PPL P++ P PQ ++ F PPP P
Sbjct: 1235 PPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLP 1268
Score = 47.0 bits (110), Expect = 8e-05
Identities = 85/323 (26%), Positives = 110/323 (34%), Gaps = 44/323 (13%)
Query: 412 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP 471
PA+PP + +P P A L LL P P SP + + S P
Sbjct: 232 PAAPPTA--VSPQPGAFLGLDRFLLG---------PSGGAGEAPGSPDTEQALSALSDLP 280
Query: 472 PSLAAPPL--QVPPSPPASP----PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALA- 524
SLAA P Q PPSP P P P+A P + P A P A P +A A
Sbjct: 281 ESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVR 340
Query: 525 -------TPPLQALPSPPASFPGQ--APFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 575
A P PG+ AP P P +A A +P
Sbjct: 341 GAGDTDEEGEEDAFEDAPRGSPGEEWAP-EVGEDAPQRLGEEPEEEAQGPDAPAAASLPG 399
Query: 576 SPPASPTLQAPRRPPTP----GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGH 631
SP S P TP +S P + + +P P R P +LS
Sbjct: 400 SPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKRRPEPSLSRGSRTAL 459
Query: 632 SSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPG----- 686
+S A P + D G G + S EL A P G + L RG
Sbjct: 460 ASVA--APAKKHRADGGLAAGLSRSADWTEELGARTPRV---GGSAHLLERGVASDSGGG 514
Query: 687 -APLPWPPATG-PGSADGLCTIY 707
+P A+G P +ADG ++
Sbjct: 515 VSPALAAKASGAPAAADGFQNVF 537
Score = 38.9 bits (89), Expect = 0.020
Identities = 50/215 (23%), Positives = 83/215 (38%), Gaps = 16/215 (7%)
Query: 165 SGPTPGTPSP-----AMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTE 219
+G PG+P A++ + E P+ PS P +E P S+ +A +
Sbjct: 260 AGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAP--SLPAAQPAAKDS 317
Query: 220 PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA-RGTPRAPAHPSQPKPKGLQ 278
PS A P AG G + + + T + A RG+P P + +
Sbjct: 318 PSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQR 377
Query: 279 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPL 338
P+ DA P ++S +P+PS P P + + T QL++P
Sbjct: 378 LGEEPEEEAQGPDA-----PAAASLPGSPAPSQRCFKPYPLITPC--YIKTTTRQLSSPN 430
Query: 339 PLAPPSPSAPPSLQTLPSPPATPPSQ-ATTSLGSP 372
SP+ P ++ P P + S+ A S+ +P
Sbjct: 431 HSPSQSPNQSPRIKRRPEPSLSRGSRTALASVAAP 465
Score = 35.8 bits (81), Expect = 0.17
Identities = 111/467 (23%), Positives = 149/467 (31%), Gaps = 60/467 (12%)
Query: 48 GAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAK 107
GA A+G + + G GG + G G S S+ + RA
Sbjct: 22 GAEDALGPRDVEATKKGSGGKKALGKHGKGGGGGGGGGESGKKKSKSDS-----RASVFS 76
Query: 108 NTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAP--KRSALSAG-ARRDT 164
N S G+ +G +R L + L+ + E A T+ P SA AG + +
Sbjct: 77 NLRIRKNLSKGKGAGGSREDVLDSQALQ-TGELDSAHSLLTKTPDLSLSADEAGLSDTEC 135
Query: 165 SGPT----PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE----HS 216
+ P PG P PA AR G P +G R S S ++ HS
Sbjct: 136 ADPFEVTGPGGPGPAEARVG-------GRPIAEDVETAAGAQDGQRTSSGSDTDIYSFHS 188
Query: 217 TTEPSP-------AARRRPSAGGGLQ-----RPASRSLSSSATPLSSPARSGPSAR---G 261
TE A R + LQ + + L + P + P P G
Sbjct: 189 ATEQEDLLSDIQQAIRLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLG 248
Query: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTL 321
R PS + + Q D +L P PSP S+AP
Sbjct: 249 LDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLP 308
Query: 322 PATPHSSSLTCQLATPLPLAPP---SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH 378
A P + A P P A P + AP + GSP +
Sbjct: 309 AAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAP 368
Query: 379 SFLPSPPLSPLATPP------PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALA 432
P L P P AP A +LP AP P PL TP
Sbjct: 369 EVGEDAP-QRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKP--YPLITP-------CY 418
Query: 433 VHLLQAPFSPPPSPPVQAP-FSPPASPPVSPSATPPSQ-APPSLAAP 477
+ S P P Q+P SP PS + S+ A S+AAP
Sbjct: 419 IKTTTRQLSSPNHSPSQSPNQSPRIKRRPEPSLSRGSRTALASVAAP 465
Score = 35.8 bits (81), Expect = 0.17
Identities = 54/205 (26%), Positives = 63/205 (30%), Gaps = 34/205 (16%)
Query: 571 LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 630
LQ P A PT +P+ G D + GP APG PD
Sbjct: 226 LQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPG--------------SPDTEQ 271
Query: 631 HSSSATSTPEELRGYDSGPE-----GGAAASPPPDAELAACHPAAWSRGPAPPLAF-RGA 684
S+ + PE L P+ GG S P L A PAA + F
Sbjct: 272 ALSALSDLPESLAAEPREPQQPPSPGGLPVSEAP--SLPAAQPAAKDSPSSTAFPFPEAG 329
Query: 685 PGAPLPWPPATGPGSAD--GLCTIYETE---------GPESATPAPGALDPGPSPGTSGG 733
PG P G G D G +E PE AP L P G
Sbjct: 330 PGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPEEEAQGP 389
Query: 734 KAAAGAGAGASSRSPKQARLGELPL 758
A A A S +P Q PL
Sbjct: 390 DAPAAASL-PGSPAPSQRCFKPYPL 413
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 124 bits (312), Expect = 3e-28
Identities = 173/626 (27%), Positives = 225/626 (35%), Gaps = 98/626 (15%)
Query: 31 GSPRPPPPVTPAALRV-LGAAGAVGRKPLA---ERAGGIGGATIPESAPRAGPTRSAGTS 86
G+ P PA + L R+ +A RA G+ ++P P A + S
Sbjct: 28 GAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVP---PAAAESPSMHRK 84
Query: 87 SRNPASRPPA-SGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL--GQKGLRISAEETVA 143
+S PP SGR PP P S R + T R G+ IS +E+ +
Sbjct: 85 QELDSSHPPKQSGR----PPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKS 140
Query: 144 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE 203
R E K S + PG S A A + V P
Sbjct: 141 RTDLKEEHKSSMM------------PGFLSEVNALS--AVSSVVNKFNPFDLI------- 179
Query: 204 GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTP 263
S S AS+ TT+ ++ G+ +P + P + P +G
Sbjct: 180 ----SDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQ---------QPPKPIPKQQGPG 226
Query: 264 RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS-AALQSQAPPTLP 322
R P PK + + +P ++ K P G P TP A L Q + P
Sbjct: 227 RDPLQ-QDGTPKSISSQQPEKI----KSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRP 281
Query: 323 ATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPS-PPATPPSQATTSLGSPTLQATHSFL 381
T + + + P + PSPS PP Q P PPA P + G A S L
Sbjct: 282 QTKQADIVRGESVKP---SLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGL 338
Query: 382 PSP-PLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQA----PNALA---- 432
P P PP PP PP Q P PA PP + P + P ALA
Sbjct: 339 TKPLAQQPGTVKPPVQPPGTTKPPAQ--PLGPAKPPAQQTGSEKPSSEQPGPKALAQPPG 396
Query: 433 VHLLQAPFSPPPSPPVQAPFSP-----------PASPPVSPSATPPSQAPPSLAAPPLQV 481
V A P PP Q +P PA P P+ TP Q P P Q
Sbjct: 397 VGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAP-GPTKTPVQQPGPG-KIPAQQA 454
Query: 482 PPSPPASPPMSPSATPPPQAPPPLAAPPLQL--AKPPPQAPPALATPPLQALPS--PPAS 537
P ++ P+ PP Q P P PP Q AKPPPQ P + A PP Q S PP
Sbjct: 455 GPGKTSAQQTGPTK-PPSQLPGPAKPPPQQPGPAKPPPQQPGS-AKPPSQQPGSTKPPPQ 512
Query: 538 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS 597
PG P PS P P +T PP P A P Q P PA P+ Q +P + T
Sbjct: 513 QPG--PAKPS---PQQPGSTKPPSQQPGSAKPSAQQPS--PAKPSAQQSTKPVS---QTG 562
Query: 598 VSGPRLTLALAPGPPPPPSRSPSSTL 623
P ++P PPS+ T+
Sbjct: 563 SGKPLQPPTVSPSAKQPPSQGLPKTI 588
Score = 117 bits (294), Expect = 3e-26
Identities = 175/728 (24%), Positives = 262/728 (35%), Gaps = 107/728 (14%)
Query: 5 RDKAKAGAAARTPAARAPGLLTPRPPGSPRP--PPPVTPAALRVLGAAGAVGRKPLAERA 62
RD + ++ +++ P + +PPG+ +P P TP +P ++A
Sbjct: 227 RDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQA 286
Query: 63 GGIGGATIPESAPRAG-PTRSAGTSSRNPASRP--PASGRGERAPPAKNTS--------P 111
+ G ++ S P P T + PA +P S G PPA+ + P
Sbjct: 287 DIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQP 346
Query: 112 GPVSSPGRASGTTRPG--PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP 169
G V P + GTT+P PLG + A++T + ++E P AL A+ G TP
Sbjct: 347 GTVKPPVQPPGTTKPPAQPLGPA--KPPAQQTGSEKPSSEQPGPKAL---AQPPGVGKTP 401
Query: 170 GT-PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRP 228
P PA + +VG P+P +P + P K+ ++ +P P
Sbjct: 402 AQQPGPA-----KPPTQQVGTPKPLAQ---QPGLQSPAKA-PGPTKTPVQQPGPGKIPAQ 452
Query: 229 SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP 288
AG G + + L PA+ P G + P P QP + +P PP
Sbjct: 453 QAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPP--PQQPGSAKPPSQQPGSTKPP 510
Query: 289 RKDAAPALG----PLSSSPLATPSPSAALQSQAP-PTLPATPHSSSLTCQLATPLPLAPP 343
+ PA P S+ P + SA +Q P P P+ S+ Q + PL PP
Sbjct: 511 PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPP 570
Query: 344 SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP 403
+ S PS + PPSQ P T L P + T +L
Sbjct: 571 TVS--PSAKQ-------PPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLC 621
Query: 404 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 463
P+P + L + Q AL L P SP P + PV+ +
Sbjct: 622 GFN--PNPHLTEVKEWLCL-NCQMKRALGGDLAPVPSSPQPKLK---------TAPVTTT 669
Query: 464 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA------APPLQLAKPPP 517
+ +P P Q P A+P S P P+ PPPL P AK PP
Sbjct: 670 SAVSKSSPQ-----PQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724
Query: 518 Q-------APPALATPPLQALPSPPASFPGQAP--FSPSASLPMSPLATPPPQAPPVLAA 568
+ APP + P + +P A + P P+ L S AT P P
Sbjct: 725 EADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQ 784
Query: 569 PLLQVPPSPPASPTLQAPRR--PPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 626
+ +PP P + PPT G +++ + P P S S + GP
Sbjct: 785 SQAEEKTTPPLKTDSAKPSQSFPPT--------GEKVSPFDSKAIPRPASDSKIISHPGP 836
Query: 627 DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPG 686
S + ++ + + SP PDA+ P P +G+P
Sbjct: 837 ---SSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAK------------PMP----KGSPT 877
Query: 687 APLPWPPA 694
P P P A
Sbjct: 878 PPGPRPTA 885
Score = 112 bits (280), Expect = 1e-24
Identities = 151/579 (26%), Positives = 202/579 (34%), Gaps = 74/579 (12%)
Query: 96 ASGRGERAPP---AKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEE----TVARGKAT 148
AS GE P A + G S G S T P + ++S EE +A
Sbjct: 5 ASLEGEGLPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQ 64
Query: 149 EAPKRSALSAGARRDT---------------SG--PTPGTPSPAMARRSRAAGT---EVG 188
PK S A A + SG P PG P+ +SR T E
Sbjct: 65 GLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQK 124
Query: 189 LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248
LP +PS + KS + E + P +A A S+ + P
Sbjct: 125 LPGRSPSTISLKES----KSRTDLKEEHKSSMMPGFLSEVNA-----LSAVSSVVNKFNP 175
Query: 249 LSSPARSGPSARGTPRAP--AHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 306
+ S S T + Q KP+G+ ++PP P K GP PL
Sbjct: 176 FDLISDSEASQEETTKKQKVVQKEQGKPEGI--IKPPLQQQPPKPIPKQQGP-GRDPLQQ 232
Query: 307 PSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAT 366
++ SQ P + + P + Q T P + A LQ S P T QA
Sbjct: 233 DGTPKSISSQQPEKIKSQPPGTGKPIQGPTQ---TPQTDHAKLPLQRDASRPQT--KQAD 287
Query: 367 TSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSP--LATPS 424
G ++ LPSP P+ P P PPA ++ P P A PP P L P
Sbjct: 288 IVRG----ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGP-AKPPAQPSGLTKPL 342
Query: 425 PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS 484
Q P + + + PP+ P+ P PPA S + P +LA PP V +
Sbjct: 343 AQQPGTVKPPVQPPGTTKPPAQPL-GPAKPPAQQTGSEKPSSEQPGPKALAQPP-GVGKT 400
Query: 485 P-----PASPPMSPSATPPPQAPPPLAAPPLQLAKP---PPQAPPALATPPLQALPS--- 533
P PA PP TP P A P P + P P Q P P QA P
Sbjct: 401 PAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTS 460
Query: 534 --------PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 585
PP+ PG A P P P P A P P PP P +
Sbjct: 461 AQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPS 520
Query: 586 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS 624
P++P + P + G A P P P ++ + +S
Sbjct: 521 PQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVS 559
Score = 111 bits (277), Expect = 3e-24
Identities = 175/697 (25%), Positives = 254/697 (36%), Gaps = 137/697 (19%)
Query: 17 PAARAPGLLTP--RPPGSPRPPP-PVTPAALRVLGAAGAVGRKPLAERAG--------GI 65
P A+ PG + P +PPG+ +PP P+ PA A KP +E+ G G+
Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP---AQQTGSEKPSSEQPGPKALAQPPGV 397
Query: 66 GGATIPESAPRAGPTRSAGTS---SRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASG 122
G + P PT+ GT ++ P + PA G P + PGP P + +G
Sbjct: 398 GKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQ--PGPGKIPAQQAG 455
Query: 123 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 182
PG + SA++T T+ P S L A+ P P P P ++
Sbjct: 456 ---PG-------KTSAQQT----GPTKPP--SQLPGPAKPPPQQPGPAKPPPQQPGSAKP 499
Query: 183 AGTEVGLPRPAPS----ARPRPPTEGPRKSVSS---ASEHSTTEPSPAARRRPSAGGGLQ 235
+ G +P P A+P P G K S +++ S +PSPA +PSA
Sbjct: 500 PSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPA---KPSAQQST- 555
Query: 236 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA 295
+P S++ S PL P S P A PSQ PK + P T P
Sbjct: 556 KPVSQT--GSGKPLQPPTVS-------PSAKQPPSQGLPK---TICPLCNTTELLLHVPE 603
Query: 296 LGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPL--PLAPPSPSAPPSLQT 353
++ + + P L L CQ+ L LAP S P L+T
Sbjct: 604 KANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKT 663
Query: 354 LPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA-TPPPQAPPALALPPL------- 405
P + S++ SP Q T + P L+ P P+ PP L P
Sbjct: 664 APVTTTSAVSKS-----SPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSA 718
Query: 406 ---QAP-------PSPPASPPL------SPLATPSPQAPNALA-----VHLLQAPFSPP- 443
Q P P+PP P + +P+A P+ P + V A P
Sbjct: 719 KAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDI 778
Query: 444 PSPPVQAPFSPPASPPVSPSATPPSQA-PPS---LAAPPLQVPPSPPASPPMSPSATPPP 499
PS VQ+ +PP+ + PSQ+ PP+ ++ + P P + + P
Sbjct: 779 PSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSS 838
Query: 500 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 559
++ P+Q + P +A ++ P A P P S +P P + P
Sbjct: 839 ESKGQKQVDPVQKKEEPKKAQTKMSPKP-DAKPMPKGSP------TPPGPRPTAGQTVPT 891
Query: 560 PQAPP----------VLAAPLLQVPPSPPASPT---------------LQAPRRPPT--- 591
PQ P + + P S P +P QA T
Sbjct: 892 PQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQ 951
Query: 592 PGPDTSVSGPRLTLALAPGPPPPPSRS--PSSTLSGP 626
PGP S SGP + AP P PP+ P ST P
Sbjct: 952 PGPH-SQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAP 987
Score = 100 bits (250), Expect = 4e-21
Identities = 171/634 (26%), Positives = 223/634 (35%), Gaps = 103/634 (16%)
Query: 138 AEETVARGKATEA--PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPS 195
A A G A+ A P +A+ AG D S + A SRA G G PA +
Sbjct: 17 AAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAA 76
Query: 196 ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 255
P S+ E ++ P + R P G RPA LS S T + RS
Sbjct: 77 ESP---------SMHRKQELDSSHPPKQSGRPPDPG----RPAQPGLSKSRT--TDTFRS 121
Query: 256 GPSARGTPRAPAHPSQPKPKGLQALRPPQ---VTPPRKDAAPALGPLSS-----SPLATP 307
G R+P+ S + K L+ + P AL +SS +P
Sbjct: 122 EQKLPG--RSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLI 179
Query: 308 SPSAALQSQAPPTLPATPHSSSLTCQLATPLPLA-PPSPSAPPSLQTLPSPPATPPSQAT 366
S S A Q + T + + P + PP PP P P Q
Sbjct: 180 SDSEASQEET------TKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQD 233
Query: 367 TSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLAT-PSP 425
G+P S P + PP P P Q P + A PL A+ P
Sbjct: 234 ---GTPK-----SISSQQPEKIKSQPPGTGKPIQG--PTQTPQTDHAKLPLQRDASRPQT 283
Query: 426 QAPNALAVHLLQAPFSPPPSPPVQAPF--SPPASPPVSPSATP-PSQAP--PSLAAPPLQ 480
+ + + ++ P PP+Q P PPA P + P P++ P PS PL
Sbjct: 284 KQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLA 343
Query: 481 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLA---KPPPQ--APPALATPPLQALPSPP 535
P P P T PP P A PP Q KP + P ALA PP + P
Sbjct: 344 QQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPP--GVGKTP 401
Query: 536 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP- 594
A PG P P P + TP P A P LQ P P PT + P + P PG
Sbjct: 402 AQQPG--PAKP----PTQQVGTPKPLAQQ----PGLQSPAKAPG-PT-KTPVQQPGPGKI 449
Query: 595 DTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAA 654
+GP T A GP PPS+ P GP A P++ GP
Sbjct: 450 PAQQAGPGKTSAQQTGPTKPPSQLP-----GP--------AKPPPQQ-----PGP----- 486
Query: 655 ASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPES 714
A PPP +A P+ PP G P P P P + T ++ P S
Sbjct: 487 AKPPPQQPGSAKPPSQQPGSTKPPPQQPG-PAKPSPQQPGS---------TKPPSQQPGS 536
Query: 715 ATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP 748
A P+ P K + G+G + P
Sbjct: 537 AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPP 570
Score = 75.1 bits (183), Expect = 3e-13
Identities = 132/598 (22%), Positives = 199/598 (33%), Gaps = 97/598 (16%)
Query: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63
K + G+ P P +P+ PGS +PP +A A KP A+++
Sbjct: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKP--SAQQPSPAKPSAQQS- 554
Query: 64 GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGT 123
T P S +G T S + A +PP+ G + P NT+ + P +A+
Sbjct: 555 -----TKPVSQTGSGKPLQPPTVSPS-AKQPPSQGLPKTICPLCNTTELLLHVPEKANFN 608
Query: 124 TRPGPLGQKGLRISAEETVA-------RGKATEAPKRSALSAGARRDTSG---PTPGTPS 173
T + TV TE + L+ +R G P P +P
Sbjct: 609 TCT----------ECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQ 658
Query: 174 PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP---SPAARRRPSA 230
P + + V P P P++ +S A E P P PSA
Sbjct: 659 PKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSA 718
Query: 231 GGGLQRPASRSLSSSATP----LSSPARSGPSARGTPRAP----------------AHPS 270
Q P + SLS A P + S P A P+ P P
Sbjct: 719 KAK-QPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPD 777
Query: 271 QPKPKGLQALRPPQVTPPRK--DAAPA---------LGPLSSSPLATPSPSAALQSQAPP 319
P K +Q+ + TPP K A P+ + P S + P+ + + S P
Sbjct: 778 IPSSK-VQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGP 836
Query: 320 TL----------------PATPHSSSLTCQLATPLPLAPPSPSAPPSL--QTLPSPPATP 361
+ P + A P+P P+P P QT+P+P +P
Sbjct: 837 SSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSP 896
Query: 362 PSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLA 421
Q + S L + S P +P T + L A AS +S
Sbjct: 897 KPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGK------LFGFGASIFSQASNLISTAG 950
Query: 422 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV 481
P P + + + QAP P P S +PP + P + + AA L+
Sbjct: 951 QPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLE- 1009
Query: 482 PPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP 539
P A + T + PPP+ A+P P L+ P P ++ P
Sbjct: 1010 ---PKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPT----KLEKSPKPESTCP 1060
Score = 62.4 bits (150), Expect = 2e-09
Identities = 88/346 (25%), Positives = 128/346 (36%), Gaps = 52/346 (15%)
Query: 309 PSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTS 368
PS+ + L T +S T P A PS PS+ +LP+ P P ++S
Sbjct: 2344 PSSVIALPMKEQLSTTYFTSGETFGQEKP---ASQLPSGSPSVSSLPAKPR--PFFRSSS 2398
Query: 369 LGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQ-- 426
L S P PP P PPP PP PP PP PP SP T P+
Sbjct: 2399 LDI-------SAQPPPPPPPPPPPPPPPPP---------PPPPPLPPPTSPKPTILPKKK 2442
Query: 427 ----APNALAVHLLQAPFSPPPSPPVQAPFSP------PASPPVSPSATPPSQAPPSLAA 476
+P A L A + + +++ P A PPV P PS P L
Sbjct: 2443 LTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPK---PSSIPSGLVF 2499
Query: 477 PPLQVPPSPPASP-PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPP 535
P PP +P P+ P Q P + P L+ L T LPSP
Sbjct: 2500 THRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMT-LNLVTSADYKLPSP- 2557
Query: 536 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD 595
+P SP ++ + P + + ++ PS P +PT + + T P
Sbjct: 2558 -----TSPLSPHSN------KSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPL 2606
Query: 596 TSVSGPRLTL--ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTP 639
S S +++ + PP P S+ ++G + ++TP
Sbjct: 2607 GSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATP 2652
Score = 57.8 bits (138), Expect = 4e-08
Identities = 89/355 (25%), Positives = 127/355 (35%), Gaps = 64/355 (18%)
Query: 282 PPQ--VTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPP--TLPATPH----SSSLTCQ 333
PP + P K+ S P++ L S +P +LPA P SSSL
Sbjct: 2343 PPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDIS 2402
Query: 334 LATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP 393
A P P PP P PP P PP PP LP PP SP T
Sbjct: 2403 -AQPPPPPPPPPPPPPP----PPPPPPPP------------------LP-PPTSPKPTIL 2438
Query: 394 PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF- 452
P+ +A P A P A ++ L T + N L V + +PPP PP +
Sbjct: 2439 PKKKLTVASPVTTATPLFDA---VTTLETTAVLRSNGLPVTRI-CTTAPPPVPPKPSSIP 2494
Query: 453 --------SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP-----PASPPMSPSATPPP 499
P+ PP++P P P+ P + P P +S ++ +
Sbjct: 2495 SGLVFTHRPEPSKPPIAPKPVIPQL--PTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADY 2552
Query: 500 QAPPPLAAPPLQLAKPPPQAPPALA-TPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 558
+ P P + K P+ +L T + LPS P + S S ++ PL +P
Sbjct: 2553 KLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGT---PTDSSASQAITSWPLGSP 2609
Query: 559 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 613
+ L+ V P P + A P + +SG T + P P
Sbjct: 2610 --------SKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAP 2656
Score = 57.0 bits (136), Expect = 7e-08
Identities = 96/372 (25%), Positives = 136/372 (36%), Gaps = 60/372 (16%)
Query: 233 GLQRPASRSLSSSATPLSSPARSGPSARGTP-RAPAHPSQPKPKGLQALRPPQVTPPRKD 291
G ++PAS+ S S + S PA+ P R + A P P P PP PP
Sbjct: 2368 GQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPP------PPPPPPPPPP 2421
Query: 292 AAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSL 351
P P +SP T P L + A P ATP ++T L T L S P +
Sbjct: 2422 PPPPPLPPPTSPKPTILPKKKL-TVASPVTTATPLFDAVT-TLETTAVLR--SNGLPVTR 2477
Query: 352 QTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP--PALALPPLQAPP 409
+PP PP ++ G L TH P P P+A P P P P P P
Sbjct: 2478 ICTTAPPPVPPKPSSIPSG---LVFTHR--PEPSKPPIA-PKPVIPQLPTTTQKPTDIHP 2531
Query: 410 SPPASPPLSPLATPSPQAPNAL--AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT-- 465
P + L+ S N + A + L +P SP +P S +SP S S T
Sbjct: 2532 KP------TGLSLTSSMTLNLVTSADYKLPSPTSP------LSPHSNKSSPRFSKSLTET 2579
Query: 466 ------PPSQAPPSLAAPPLQVPPSPPASPPMS-PSATPPPQAPPPLAAPPLQLAKPPP- 517
P P+ ++ + P SP S P PP+ A + ++
Sbjct: 2580 YVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTF 2639
Query: 518 ---------QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV-LA 567
A P A QA P+ F + + + ++ AP V L+
Sbjct: 2640 YISGALQTFSATPVTAPSSFQAAPTSVTQF-------LTTEVSKTEVSATRSTAPSVGLS 2692
Query: 568 APLLQVPPSPPA 579
+ + +PP P A
Sbjct: 2693 SISITIPPEPLA 2704
Score = 48.9 bits (115), Expect = 2e-05
Identities = 71/296 (23%), Positives = 101/296 (34%), Gaps = 58/296 (19%)
Query: 169 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSAS--------EHSTTEP 220
P P P S + P P P P PP P + + + T
Sbjct: 2387 PAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVA 2446
Query: 221 SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL 280
SP P + L S+ P++ + P P P PS P GL
Sbjct: 2447 SPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP-----PPVPPKPSS-IPSGLVFT 2500
Query: 281 RPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPH----SSSLTCQLAT 336
P+ + P P++ P+ P+ +Q P + P +SS+T L T
Sbjct: 2501 HRPEPSKP---------PIAPKPVIPQLPTT---TQKPTDIHPKPTGLSLTSSMTLNLVT 2548
Query: 337 PLPLAPPSPSAPPS-------------------LQTLPSPPATP----PSQATTS--LGS 371
PSP++P S + TLPS P TP SQA TS LGS
Sbjct: 2549 SADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGS 2608
Query: 372 PT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS 424
P+ + F PP++ + P LQ + P + P S A P+
Sbjct: 2609 PSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPT 2664
Score = 34.7 bits (78), Expect = 0.39
Identities = 38/141 (26%), Positives = 55/141 (39%), Gaps = 10/141 (7%)
Query: 406 QAPPSPPASPPLSPLATPSP----QAPNALAVHLLQAPFSPPPSPPV-QAPFSPPASPPV 460
Q+P A+ P P+P + + A +Q SPP SP V +P SP +
Sbjct: 3576 QSPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKA 3635
Query: 461 SPSATPPSQAP-PSLAAPPLQVPPS----PPASPPMSPSATPPPQAPPPLAAPPLQLAKP 515
SA P + P P +P + P PPASP + P PL+ + ++
Sbjct: 3636 LESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRA 3695
Query: 516 PPQAPPALATPPLQALPSPPA 536
P Q T Q + S A
Sbjct: 3696 PFQYTEGYTTKGSQTMTSSGA 3716
Score = 33.9 bits (76), Expect = 0.66
Identities = 93/391 (23%), Positives = 126/391 (32%), Gaps = 79/391 (20%)
Query: 18 AARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRA 77
+A+ P P PP P PPPP P + K A + AT A
Sbjct: 2402 SAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTT 2461
Query: 78 GPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 137
T + S+ P +R + APP P P S P T RP P
Sbjct: 2462 LETTAVLRSNGLPVTRICTT-----APPP--VPPKPSSIPSGLVFTHRPEP--------- 2505
Query: 138 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR 197
K APK + T PT P P S + + L A
Sbjct: 2506 -------SKPPIAPK--PVIPQLPTTTQKPTDIHPKP--TGLSLTSSMTLNLVTSADYKL 2554
Query: 198 PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP 257
P P S S HS + SP S+SL+ + ++ P
Sbjct: 2555 PSP--------TSPLSPHS-NKSSPR--------------FSKSLTETYVVITL-----P 2586
Query: 258 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQA 317
S GTP QA+ + P KD +S P+ + P
Sbjct: 2587 SEPGTP--------TDSSASQAITSWPLGSPSKDL------VSVEPVFSVVP-------- 2624
Query: 318 PPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQAT 377
P T P SS T ++ L +P PS + + P + TT + + AT
Sbjct: 2625 PVTAVEIPISSEQTFYISGALQTFSATPVTAPS--SFQAAPTSVTQFLTTEVSKTEVSAT 2682
Query: 378 HSFLPSPPLSPLATPPPQAPPALALPPLQAP 408
S PS LS ++ P P AL L+ P
Sbjct: 2683 RSTAPSVGLSSISITIPPEPLALDNIHLEKP 2713
Score = 33.5 bits (75), Expect = 0.86
Identities = 32/125 (25%), Positives = 46/125 (36%), Gaps = 3/125 (2%)
Query: 441 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 500
S SP + SPP P+ + A +Q+ PSPP SP + S P
Sbjct: 3573 SDTQSPQYLSATSPPKDKK-RPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLS 3631
Query: 501 APPPLAAPPLQLAKPPPQ--APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 558
L + + KP P +P + P + +P S S P+SP A
Sbjct: 3632 PGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADE 3691
Query: 559 PPQAP 563
+AP
Sbjct: 3692 SSRAP 3696
Score = 32.3 bits (72), Expect = 1.9
Identities = 39/152 (25%), Positives = 50/152 (32%), Gaps = 18/152 (11%)
Query: 324 TPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPS 383
T SL CQ S + P + SPP +G S L +
Sbjct: 3559 TYKGGSLGCQTEAD------SDTQSPQYLSATSPPKDKKRPTPLEIGYS------SHLRA 3606
Query: 384 PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 443
LA PP++P L P P P P P + V PP
Sbjct: 3607 DSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPP 3666
Query: 444 PSPP----VQAPFSPPASPPVSPSATPPSQAP 471
SP +Q S P P+SP+A S+AP
Sbjct: 3667 ASPKTAKMMQRSMSDP--KPLSPTADESSRAP 3696
Score = 32.3 bits (72), Expect = 1.9
Identities = 37/141 (26%), Positives = 52/141 (36%), Gaps = 22/141 (15%)
Query: 299 LSSSPLATPSPSAALQSQ----APPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTL 354
+S S +++ P+ ++SQ P T P T S + Q T L PP+ P Q
Sbjct: 3834 MSDSEVSSTRPTR-IESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPT---SPYTQYQ 3889
Query: 355 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS 414
S PA P QA S+ Q P P QA + +
Sbjct: 3890 YSSPALP------------TQAPTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFT 3937
Query: 415 PPLSPLATPSP--QAPNALAV 433
P + P TP P Q P+ + V
Sbjct: 3938 PQVQPTPTPQPSYQLPSQMMV 3958
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 124 bits (312), Expect = 3e-28
Identities = 173/626 (27%), Positives = 225/626 (35%), Gaps = 98/626 (15%)
Query: 31 GSPRPPPPVTPAALRV-LGAAGAVGRKPLA---ERAGGIGGATIPESAPRAGPTRSAGTS 86
G+ P PA + L R+ +A RA G+ ++P P A + S
Sbjct: 28 GAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVP---PAAAESPSMHRK 84
Query: 87 SRNPASRPPA-SGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL--GQKGLRISAEETVA 143
+S PP SGR PP P S R + T R G+ IS +E+ +
Sbjct: 85 QELDSSHPPKQSGR----PPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKS 140
Query: 144 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE 203
R E K S + PG S A A + V P
Sbjct: 141 RTDLKEEHKSSMM------------PGFLSEVNALS--AVSSVVNKFNPFDLI------- 179
Query: 204 GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTP 263
S S AS+ TT+ ++ G+ +P + P + P +G
Sbjct: 180 ----SDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQ---------QPPKPIPKQQGPG 226
Query: 264 RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS-AALQSQAPPTLP 322
R P PK + + +P ++ K P G P TP A L Q + P
Sbjct: 227 RDPLQ-QDGTPKSISSQQPEKI----KSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRP 281
Query: 323 ATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPS-PPATPPSQATTSLGSPTLQATHSFL 381
T + + + P + PSPS PP Q P PPA P + G A S L
Sbjct: 282 QTKQADIVRGESVKP---SLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGL 338
Query: 382 PSP-PLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQA----PNALA---- 432
P P PP PP PP Q P PA PP + P + P ALA
Sbjct: 339 TKPLAQQPGTVKPPVQPPGTTKPPAQ--PLGPAKPPAQQTGSEKPSSEQPGPKALAQPPG 396
Query: 433 VHLLQAPFSPPPSPPVQAPFSP-----------PASPPVSPSATPPSQAPPSLAAPPLQV 481
V A P PP Q +P PA P P+ TP Q P P Q
Sbjct: 397 VGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAP-GPTKTPVQQPGPG-KIPAQQA 454
Query: 482 PPSPPASPPMSPSATPPPQAPPPLAAPPLQL--AKPPPQAPPALATPPLQALPS--PPAS 537
P ++ P+ PP Q P P PP Q AKPPPQ P + A PP Q S PP
Sbjct: 455 GPGKTSAQQTGPTK-PPSQLPGPAKPPPQQPGPAKPPPQQPGS-AKPPSQQPGSTKPPPQ 512
Query: 538 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS 597
PG P PS P P +T PP P A P Q P PA P+ Q +P + T
Sbjct: 513 QPG--PAKPS---PQQPGSTKPPSQQPGSAKPSAQQPS--PAKPSAQQSTKPVS---QTG 562
Query: 598 VSGPRLTLALAPGPPPPPSRSPSSTL 623
P ++P PPS+ T+
Sbjct: 563 SGKPLQPPTVSPSAKQPPSQGLPKTI 588
Score = 117 bits (294), Expect = 3e-26
Identities = 175/728 (24%), Positives = 262/728 (35%), Gaps = 107/728 (14%)
Query: 5 RDKAKAGAAARTPAARAPGLLTPRPPGSPRP--PPPVTPAALRVLGAAGAVGRKPLAERA 62
RD + ++ +++ P + +PPG+ +P P TP +P ++A
Sbjct: 227 RDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQA 286
Query: 63 GGIGGATIPESAPRAG-PTRSAGTSSRNPASRP--PASGRGERAPPAKNTS--------P 111
+ G ++ S P P T + PA +P S G PPA+ + P
Sbjct: 287 DIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQP 346
Query: 112 GPVSSPGRASGTTRPG--PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP 169
G V P + GTT+P PLG + A++T + ++E P AL A+ G TP
Sbjct: 347 GTVKPPVQPPGTTKPPAQPLGPA--KPPAQQTGSEKPSSEQPGPKAL---AQPPGVGKTP 401
Query: 170 GT-PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRP 228
P PA + +VG P+P +P + P K+ ++ +P P
Sbjct: 402 AQQPGPA-----KPPTQQVGTPKPLAQ---QPGLQSPAKA-PGPTKTPVQQPGPGKIPAQ 452
Query: 229 SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP 288
AG G + + L PA+ P G + P P QP + +P PP
Sbjct: 453 QAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPP--PQQPGSAKPPSQQPGSTKPP 510
Query: 289 RKDAAPALG----PLSSSPLATPSPSAALQSQAP-PTLPATPHSSSLTCQLATPLPLAPP 343
+ PA P S+ P + SA +Q P P P+ S+ Q + PL PP
Sbjct: 511 PQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPP 570
Query: 344 SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP 403
+ S PS + PPSQ P T L P + T +L
Sbjct: 571 TVS--PSAKQ-------PPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLC 621
Query: 404 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 463
P+P + L + Q AL L P SP P + PV+ +
Sbjct: 622 GFN--PNPHLTEVKEWLCL-NCQMKRALGGDLAPVPSSPQPKLK---------TAPVTTT 669
Query: 464 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA------APPLQLAKPPP 517
+ +P P Q P A+P S P P+ PPPL P AK PP
Sbjct: 670 SAVSKSSPQ-----PQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724
Query: 518 Q-------APPALATPPLQALPSPPASFPGQAP--FSPSASLPMSPLATPPPQAPPVLAA 568
+ APP + P + +P A + P P+ L S AT P P
Sbjct: 725 EADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQ 784
Query: 569 PLLQVPPSPPASPTLQAPRR--PPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 626
+ +PP P + PPT G +++ + P P S S + GP
Sbjct: 785 SQAEEKTTPPLKTDSAKPSQSFPPT--------GEKVSPFDSKAIPRPASDSKIISHPGP 836
Query: 627 DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPG 686
S + ++ + + SP PDA+ P P +G+P
Sbjct: 837 ---SSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAK------------PMP----KGSPT 877
Query: 687 APLPWPPA 694
P P P A
Sbjct: 878 PPGPRPTA 885
Score = 112 bits (280), Expect = 1e-24
Identities = 151/579 (26%), Positives = 202/579 (34%), Gaps = 74/579 (12%)
Query: 96 ASGRGERAPP---AKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEE----TVARGKAT 148
AS GE P A + G S G S T P + ++S EE +A
Sbjct: 5 ASLEGEGLPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQ 64
Query: 149 EAPKRSALSAGARRDT---------------SG--PTPGTPSPAMARRSRAAGT---EVG 188
PK S A A + SG P PG P+ +SR T E
Sbjct: 65 GLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQK 124
Query: 189 LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248
LP +PS + KS + E + P +A A S+ + P
Sbjct: 125 LPGRSPSTISLKES----KSRTDLKEEHKSSMMPGFLSEVNA-----LSAVSSVVNKFNP 175
Query: 249 LSSPARSGPSARGTPRAP--AHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 306
+ S S T + Q KP+G+ ++PP P K GP PL
Sbjct: 176 FDLISDSEASQEETTKKQKVVQKEQGKPEGI--IKPPLQQQPPKPIPKQQGP-GRDPLQQ 232
Query: 307 PSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAT 366
++ SQ P + + P + Q T P + A LQ S P T QA
Sbjct: 233 DGTPKSISSQQPEKIKSQPPGTGKPIQGPTQ---TPQTDHAKLPLQRDASRPQT--KQAD 287
Query: 367 TSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSP--LATPS 424
G ++ LPSP P+ P P PPA ++ P P A PP P L P
Sbjct: 288 IVRG----ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGP-AKPPAQPSGLTKPL 342
Query: 425 PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS 484
Q P + + + PP+ P+ P PPA S + P +LA PP V +
Sbjct: 343 AQQPGTVKPPVQPPGTTKPPAQPL-GPAKPPAQQTGSEKPSSEQPGPKALAQPP-GVGKT 400
Query: 485 P-----PASPPMSPSATPPPQAPPPLAAPPLQLAKP---PPQAPPALATPPLQALPS--- 533
P PA PP TP P A P P + P P Q P P QA P
Sbjct: 401 PAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTS 460
Query: 534 --------PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 585
PP+ PG A P P P P A P P PP P +
Sbjct: 461 AQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPS 520
Query: 586 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS 624
P++P + P + G A P P P ++ + +S
Sbjct: 521 PQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVS 559
Score = 111 bits (277), Expect = 3e-24
Identities = 175/697 (25%), Positives = 254/697 (36%), Gaps = 137/697 (19%)
Query: 17 PAARAPGLLTP--RPPGSPRPPP-PVTPAALRVLGAAGAVGRKPLAERAG--------GI 65
P A+ PG + P +PPG+ +PP P+ PA A KP +E+ G G+
Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP---AQQTGSEKPSSEQPGPKALAQPPGV 397
Query: 66 GGATIPESAPRAGPTRSAGTS---SRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASG 122
G + P PT+ GT ++ P + PA G P + PGP P + +G
Sbjct: 398 GKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQ--PGPGKIPAQQAG 455
Query: 123 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 182
PG + SA++T T+ P S L A+ P P P P ++
Sbjct: 456 ---PG-------KTSAQQT----GPTKPP--SQLPGPAKPPPQQPGPAKPPPQQPGSAKP 499
Query: 183 AGTEVGLPRPAPS----ARPRPPTEGPRKSVSS---ASEHSTTEPSPAARRRPSAGGGLQ 235
+ G +P P A+P P G K S +++ S +PSPA +PSA
Sbjct: 500 PSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPA---KPSAQQST- 555
Query: 236 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA 295
+P S++ S PL P S P A PSQ PK + P T P
Sbjct: 556 KPVSQT--GSGKPLQPPTVS-------PSAKQPPSQGLPK---TICPLCNTTELLLHVPE 603
Query: 296 LGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPL--PLAPPSPSAPPSLQT 353
++ + + P L L CQ+ L LAP S P L+T
Sbjct: 604 KANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKT 663
Query: 354 LPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA-TPPPQAPPALALPPL------- 405
P + S++ SP Q T + P L+ P P+ PP L P
Sbjct: 664 APVTTTSAVSKS-----SPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSA 718
Query: 406 ---QAP-------PSPPASPPL------SPLATPSPQAPNALA-----VHLLQAPFSPP- 443
Q P P+PP P + +P+A P+ P + V A P
Sbjct: 719 KAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDI 778
Query: 444 PSPPVQAPFSPPASPPVSPSATPPSQA-PPS---LAAPPLQVPPSPPASPPMSPSATPPP 499
PS VQ+ +PP+ + PSQ+ PP+ ++ + P P + + P
Sbjct: 779 PSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSS 838
Query: 500 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 559
++ P+Q + P +A ++ P A P P S +P P + P
Sbjct: 839 ESKGQKQVDPVQKKEEPKKAQTKMSPKP-DAKPMPKGSP------TPPGPRPTAGQTVPT 891
Query: 560 PQAPP----------VLAAPLLQVPPSPPASPT---------------LQAPRRPPT--- 591
PQ P + + P S P +P QA T
Sbjct: 892 PQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQ 951
Query: 592 PGPDTSVSGPRLTLALAPGPPPPPSRS--PSSTLSGP 626
PGP S SGP + AP P PP+ P ST P
Sbjct: 952 PGPH-SQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAP 987
Score = 100 bits (250), Expect = 4e-21
Identities = 171/634 (26%), Positives = 223/634 (35%), Gaps = 103/634 (16%)
Query: 138 AEETVARGKATEA--PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPS 195
A A G A+ A P +A+ AG D S + A SRA G G PA +
Sbjct: 17 AAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAA 76
Query: 196 ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 255
P S+ E ++ P + R P G RPA LS S T + RS
Sbjct: 77 ESP---------SMHRKQELDSSHPPKQSGRPPDPG----RPAQPGLSKSRT--TDTFRS 121
Query: 256 GPSARGTPRAPAHPSQPKPKGLQALRPPQ---VTPPRKDAAPALGPLSS-----SPLATP 307
G R+P+ S + K L+ + P AL +SS +P
Sbjct: 122 EQKLPG--RSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLI 179
Query: 308 SPSAALQSQAPPTLPATPHSSSLTCQLATPLPLA-PPSPSAPPSLQTLPSPPATPPSQAT 366
S S A Q + T + + P + PP PP P P Q
Sbjct: 180 SDSEASQEET------TKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQD 233
Query: 367 TSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLAT-PSP 425
G+P S P + PP P P Q P + A PL A+ P
Sbjct: 234 ---GTPK-----SISSQQPEKIKSQPPGTGKPIQG--PTQTPQTDHAKLPLQRDASRPQT 283
Query: 426 QAPNALAVHLLQAPFSPPPSPPVQAPF--SPPASPPVSPSATP-PSQAP--PSLAAPPLQ 480
+ + + ++ P PP+Q P PPA P + P P++ P PS PL
Sbjct: 284 KQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLA 343
Query: 481 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLA---KPPPQ--APPALATPPLQALPSPP 535
P P P T PP P A PP Q KP + P ALA PP + P
Sbjct: 344 QQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPP--GVGKTP 401
Query: 536 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP- 594
A PG P P P + TP P A P LQ P P PT + P + P PG
Sbjct: 402 AQQPG--PAKP----PTQQVGTPKPLAQQ----PGLQSPAKAPG-PT-KTPVQQPGPGKI 449
Query: 595 DTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAA 654
+GP T A GP PPS+ P GP A P++ GP
Sbjct: 450 PAQQAGPGKTSAQQTGPTKPPSQLP-----GP--------AKPPPQQ-----PGP----- 486
Query: 655 ASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPES 714
A PPP +A P+ PP G P P P P + T ++ P S
Sbjct: 487 AKPPPQQPGSAKPPSQQPGSTKPPPQQPG-PAKPSPQQPGS---------TKPPSQQPGS 536
Query: 715 ATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP 748
A P+ P K + G+G + P
Sbjct: 537 AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPP 570
Score = 75.1 bits (183), Expect = 3e-13
Identities = 132/598 (22%), Positives = 199/598 (33%), Gaps = 97/598 (16%)
Query: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63
K + G+ P P +P+ PGS +PP +A A KP A+++
Sbjct: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKP--SAQQPSPAKPSAQQS- 554
Query: 64 GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGT 123
T P S +G T S + A +PP+ G + P NT+ + P +A+
Sbjct: 555 -----TKPVSQTGSGKPLQPPTVSPS-AKQPPSQGLPKTICPLCNTTELLLHVPEKANFN 608
Query: 124 TRPGPLGQKGLRISAEETVA-------RGKATEAPKRSALSAGARRDTSG---PTPGTPS 173
T + TV TE + L+ +R G P P +P
Sbjct: 609 TCT----------ECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQ 658
Query: 174 PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP---SPAARRRPSA 230
P + + V P P P++ +S A E P P PSA
Sbjct: 659 PKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSA 718
Query: 231 GGGLQRPASRSLSSSATP----LSSPARSGPSARGTPRAP----------------AHPS 270
Q P + SLS A P + S P A P+ P P
Sbjct: 719 KAK-QPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPD 777
Query: 271 QPKPKGLQALRPPQVTPPRK--DAAPA---------LGPLSSSPLATPSPSAALQSQAPP 319
P K +Q+ + TPP K A P+ + P S + P+ + + S P
Sbjct: 778 IPSSK-VQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGP 836
Query: 320 TL----------------PATPHSSSLTCQLATPLPLAPPSPSAPPSL--QTLPSPPATP 361
+ P + A P+P P+P P QT+P+P +P
Sbjct: 837 SSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSP 896
Query: 362 PSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLA 421
Q + S L + S P +P T + L A AS +S
Sbjct: 897 KPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGK------LFGFGASIFSQASNLISTAG 950
Query: 422 TPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV 481
P P + + + QAP P P S +PP + P + + AA L+
Sbjct: 951 QPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLE- 1009
Query: 482 PPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP 539
P A + T + PPP+ A+P P L+ P P ++ P
Sbjct: 1010 ---PKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPT----KLEKSPKPESTCP 1060
Score = 62.4 bits (150), Expect = 2e-09
Identities = 88/346 (25%), Positives = 128/346 (36%), Gaps = 52/346 (15%)
Query: 309 PSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTS 368
PS+ + L T +S T P A PS PS+ +LP+ P P ++S
Sbjct: 2344 PSSVIALPMKEQLSTTYFTSGETFGQEKP---ASQLPSGSPSVSSLPAKPR--PFFRSSS 2398
Query: 369 LGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQ-- 426
L S P PP P PPP PP PP PP PP SP T P+
Sbjct: 2399 LDI-------SAQPPPPPPPPPPPPPPPPP---------PPPPPLPPPTSPKPTILPKKK 2442
Query: 427 ----APNALAVHLLQAPFSPPPSPPVQAPFSP------PASPPVSPSATPPSQAPPSLAA 476
+P A L A + + +++ P A PPV P PS P L
Sbjct: 2443 LTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPK---PSSIPSGLVF 2499
Query: 477 PPLQVPPSPPASP-PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPP 535
P PP +P P+ P Q P + P L+ L T LPSP
Sbjct: 2500 THRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMT-LNLVTSADYKLPSP- 2557
Query: 536 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD 595
+P SP ++ + P + + ++ PS P +PT + + T P
Sbjct: 2558 -----TSPLSPHSN------KSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPL 2606
Query: 596 TSVSGPRLTL--ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTP 639
S S +++ + PP P S+ ++G + ++TP
Sbjct: 2607 GSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATP 2652
Score = 57.8 bits (138), Expect = 4e-08
Identities = 89/355 (25%), Positives = 127/355 (35%), Gaps = 64/355 (18%)
Query: 282 PPQ--VTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPP--TLPATPH----SSSLTCQ 333
PP + P K+ S P++ L S +P +LPA P SSSL
Sbjct: 2343 PPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDIS 2402
Query: 334 LATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP 393
A P P PP P PP P PP PP LP PP SP T
Sbjct: 2403 -AQPPPPPPPPPPPPPP----PPPPPPPP------------------LP-PPTSPKPTIL 2438
Query: 394 PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF- 452
P+ +A P A P A ++ L T + N L V + +PPP PP +
Sbjct: 2439 PKKKLTVASPVTTATPLFDA---VTTLETTAVLRSNGLPVTRI-CTTAPPPVPPKPSSIP 2494
Query: 453 --------SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP-----PASPPMSPSATPPP 499
P+ PP++P P P+ P + P P +S ++ +
Sbjct: 2495 SGLVFTHRPEPSKPPIAPKPVIPQL--PTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADY 2552
Query: 500 QAPPPLAAPPLQLAKPPPQAPPALA-TPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 558
+ P P + K P+ +L T + LPS P + S S ++ PL +P
Sbjct: 2553 KLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGT---PTDSSASQAITSWPLGSP 2609
Query: 559 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 613
+ L+ V P P + A P + +SG T + P P
Sbjct: 2610 --------SKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAP 2656
Score = 57.0 bits (136), Expect = 7e-08
Identities = 96/372 (25%), Positives = 136/372 (36%), Gaps = 60/372 (16%)
Query: 233 GLQRPASRSLSSSATPLSSPARSGPSARGTP-RAPAHPSQPKPKGLQALRPPQVTPPRKD 291
G ++PAS+ S S + S PA+ P R + A P P P PP PP
Sbjct: 2368 GQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPP------PPPPPPPPPP 2421
Query: 292 AAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSL 351
P P +SP T P L + A P ATP ++T L T L S P +
Sbjct: 2422 PPPPPLPPPTSPKPTILPKKKL-TVASPVTTATPLFDAVT-TLETTAVLR--SNGLPVTR 2477
Query: 352 QTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP--PALALPPLQAPP 409
+PP PP ++ G L TH P P P+A P P P P P P
Sbjct: 2478 ICTTAPPPVPPKPSSIPSG---LVFTHR--PEPSKPPIA-PKPVIPQLPTTTQKPTDIHP 2531
Query: 410 SPPASPPLSPLATPSPQAPNAL--AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT-- 465
P + L+ S N + A + L +P SP +P S +SP S S T
Sbjct: 2532 KP------TGLSLTSSMTLNLVTSADYKLPSPTSP------LSPHSNKSSPRFSKSLTET 2579
Query: 466 ------PPSQAPPSLAAPPLQVPPSPPASPPMS-PSATPPPQAPPPLAAPPLQLAKPPP- 517
P P+ ++ + P SP S P PP+ A + ++
Sbjct: 2580 YVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTF 2639
Query: 518 ---------QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV-LA 567
A P A QA P+ F + + + ++ AP V L+
Sbjct: 2640 YISGALQTFSATPVTAPSSFQAAPTSVTQF-------LTTEVSKTEVSATRSTAPSVGLS 2692
Query: 568 APLLQVPPSPPA 579
+ + +PP P A
Sbjct: 2693 SISITIPPEPLA 2704
Score = 48.9 bits (115), Expect = 2e-05
Identities = 71/296 (23%), Positives = 101/296 (34%), Gaps = 58/296 (19%)
Query: 169 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSAS--------EHSTTEP 220
P P P S + P P P P PP P + + + T
Sbjct: 2387 PAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVA 2446
Query: 221 SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL 280
SP P + L S+ P++ + P P P PS P GL
Sbjct: 2447 SPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP-----PPVPPKPSS-IPSGLVFT 2500
Query: 281 RPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPH----SSSLTCQLAT 336
P+ + P P++ P+ P+ +Q P + P +SS+T L T
Sbjct: 2501 HRPEPSKP---------PIAPKPVIPQLPTT---TQKPTDIHPKPTGLSLTSSMTLNLVT 2548
Query: 337 PLPLAPPSPSAPPS-------------------LQTLPSPPATP----PSQATTS--LGS 371
PSP++P S + TLPS P TP SQA TS LGS
Sbjct: 2549 SADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGS 2608
Query: 372 PT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS 424
P+ + F PP++ + P LQ + P + P S A P+
Sbjct: 2609 PSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPT 2664
Score = 34.7 bits (78), Expect = 0.39
Identities = 38/141 (26%), Positives = 55/141 (39%), Gaps = 10/141 (7%)
Query: 406 QAPPSPPASPPLSPLATPSP----QAPNALAVHLLQAPFSPPPSPPV-QAPFSPPASPPV 460
Q+P A+ P P+P + + A +Q SPP SP V +P SP +
Sbjct: 3576 QSPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKA 3635
Query: 461 SPSATPPSQAP-PSLAAPPLQVPPS----PPASPPMSPSATPPPQAPPPLAAPPLQLAKP 515
SA P + P P +P + P PPASP + P PL+ + ++
Sbjct: 3636 LESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRA 3695
Query: 516 PPQAPPALATPPLQALPSPPA 536
P Q T Q + S A
Sbjct: 3696 PFQYTEGYTTKGSQTMTSSGA 3716
Score = 33.9 bits (76), Expect = 0.66
Identities = 93/391 (23%), Positives = 126/391 (32%), Gaps = 79/391 (20%)
Query: 18 AARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRA 77
+A+ P P PP P PPPP P + K A + AT A
Sbjct: 2402 SAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTT 2461
Query: 78 GPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 137
T + S+ P +R + APP P P S P T RP P
Sbjct: 2462 LETTAVLRSNGLPVTRICTT-----APPP--VPPKPSSIPSGLVFTHRPEP--------- 2505
Query: 138 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR 197
K APK + T PT P P S + + L A
Sbjct: 2506 -------SKPPIAPK--PVIPQLPTTTQKPTDIHPKP--TGLSLTSSMTLNLVTSADYKL 2554
Query: 198 PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP 257
P P S S HS + SP S+SL+ + ++ P
Sbjct: 2555 PSP--------TSPLSPHS-NKSSPR--------------FSKSLTETYVVITL-----P 2586
Query: 258 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQA 317
S GTP QA+ + P KD +S P+ + P
Sbjct: 2587 SEPGTP--------TDSSASQAITSWPLGSPSKDL------VSVEPVFSVVP-------- 2624
Query: 318 PPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQAT 377
P T P SS T ++ L +P PS + + P + TT + + AT
Sbjct: 2625 PVTAVEIPISSEQTFYISGALQTFSATPVTAPS--SFQAAPTSVTQFLTTEVSKTEVSAT 2682
Query: 378 HSFLPSPPLSPLATPPPQAPPALALPPLQAP 408
S PS LS ++ P P AL L+ P
Sbjct: 2683 RSTAPSVGLSSISITIPPEPLALDNIHLEKP 2713
Score = 33.5 bits (75), Expect = 0.86
Identities = 32/125 (25%), Positives = 46/125 (36%), Gaps = 3/125 (2%)
Query: 441 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 500
S SP + SPP P+ + A +Q+ PSPP SP + S P
Sbjct: 3573 SDTQSPQYLSATSPPKDKK-RPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLS 3631
Query: 501 APPPLAAPPLQLAKPPPQ--APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 558
L + + KP P +P + P + +P S S P+SP A
Sbjct: 3632 PGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADE 3691
Query: 559 PPQAP 563
+AP
Sbjct: 3692 SSRAP 3696
Score = 32.3 bits (72), Expect = 1.9
Identities = 39/152 (25%), Positives = 50/152 (32%), Gaps = 18/152 (11%)
Query: 324 TPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPS 383
T SL CQ S + P + SPP +G S L +
Sbjct: 3559 TYKGGSLGCQTEAD------SDTQSPQYLSATSPPKDKKRPTPLEIGYS------SHLRA 3606
Query: 384 PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 443
LA PP++P L P P P P P + V PP
Sbjct: 3607 DSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPP 3666
Query: 444 PSPP----VQAPFSPPASPPVSPSATPPSQAP 471
SP +Q S P P+SP+A S+AP
Sbjct: 3667 ASPKTAKMMQRSMSDP--KPLSPTADESSRAP 3696
Score = 32.3 bits (72), Expect = 1.9
Identities = 37/141 (26%), Positives = 52/141 (36%), Gaps = 22/141 (15%)
Query: 299 LSSSPLATPSPSAALQSQ----APPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTL 354
+S S +++ P+ ++SQ P T P T S + Q T L PP+ P Q
Sbjct: 3834 MSDSEVSSTRPTR-IESQHGIERPRTAPQTEFSQFIPPQTQTESQLVPPT---SPYTQYQ 3889
Query: 355 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS 414
S PA P QA S+ Q P P QA + +
Sbjct: 3890 YSSPALP------------TQAPTSYTQQSHFEQQTLYHQQVSPYQTQPTFQAVATMSFT 3937
Query: 415 PPLSPLATPSP--QAPNALAV 433
P + P TP P Q P+ + V
Sbjct: 3938 PQVQPTPTPQPSYQLPSQMMV 3958
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.127 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 57,506,354
Number of Sequences: 37866
Number of extensions: 4993575
Number of successful extensions: 180804
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 2047
Number of HSP's successfully gapped in prelim test: 3548
Number of HSP's that attempted gapping in prelim test: 24928
Number of HSP's gapped (non-prelim): 54003
length of query: 855
length of database: 18,247,518
effective HSP length: 111
effective length of query: 744
effective length of database: 14,044,392
effective search space: 10449027648
effective search space used: 10449027648
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.