Guide to the Human Genome
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Search of human proteins with 239756926

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239756926 PREDICTED: similar to TBC1 domain family, member 3
[Homo sapiens]
         (424 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239756926 PREDICTED: similar to TBC1 domain family, member 3 ...   909   0.0  
gi|226693407 TBC1 domain family, member 3H [Homo sapiens]             495   e-140
gi|183583563 TBC1 domain family, member 3D [Homo sapiens]             495   e-140
gi|90577185 TBC1 domain family member 3C [Homo sapiens]               495   e-140
gi|157502205 TBC1 domain family, member 3G [Homo sapiens]             495   e-140
gi|14149985 TBC1 domain family, member 3F [Homo sapiens]              494   e-140
gi|183583565 TBC1 domain family, member 3 [Homo sapiens]              494   e-140
gi|183583567 TBC1 domain family, member 3E [Homo sapiens]             494   e-140
gi|149999613 TBC1 domain family, member 3B [Homo sapiens]             491   e-139
gi|109638751 ubiquitin specific protease 6 [Homo sapiens]             332   4e-91
gi|239745813 PREDICTED: hypothetical protein XP_002343595 [Homo ...   179   3e-45
gi|239756790 PREDICTED: similar to hCG1991532 [Homo sapiens]          177   2e-44
gi|239751314 PREDICTED: hypothetical protein XP_002347802 [Homo ...   149   4e-36
gi|148235002 TBC1 domain family, member 26 [Homo sapiens]             149   6e-36
gi|239756750 PREDICTED: similar to TBC1 domain family, member 28...   140   2e-33
gi|151108489 TBC1 domain family, member 28 [Homo sapiens]             140   2e-33
gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens]              121   1e-27
gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens]            121   1e-27
gi|241982780 programmed cell death 6 interacting protein isoform...    47   4e-05
gi|22027538 programmed cell death 6 interacting protein isoform ...    47   4e-05
gi|239756746 PREDICTED: TBC1 domain family, member 27 [Homo sapi...    47   4e-05
gi|239745731 PREDICTED: TBC1 domain family, member 27 [Homo sapi...    46   6e-05
gi|167614488 TBC1 domain family, member 10B [Homo sapiens]             46   6e-05
gi|239751241 PREDICTED: TBC1 domain family, member 27 [Homo sapi...    45   1e-04
gi|13994322 TBC1 domain family, member 10A [Homo sapiens]              44   3e-04
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    42   0.001
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    41   0.002
gi|156616290 collagen type VI alpha 6 [Homo sapiens]                   40   0.003
gi|157785645 SPEG complex locus [Homo sapiens]                         39   0.007
gi|38348348 TBC1 domain family, member 10C [Homo sapiens]              39   0.007

>gi|239756926 PREDICTED: similar to TBC1 domain family, member 3
           [Homo sapiens]
          Length = 424

 Score =  909 bits (2349), Expect = 0.0
 Identities = 424/424 (100%), Positives = 424/424 (100%)

Query: 1   MDVVEVVGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFGSYNNNIDHFGMQHETELPPL 60
           MDVVEVVGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFGSYNNNIDHFGMQHETELPPL
Sbjct: 1   MDVVEVVGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFGSYNNNIDHFGMQHETELPPL 60

Query: 61  TAREVKQIRREISRKSKWVKMLGEWDTYKNSRKLIDRAYQGIPMNIRGPMWSVLLNIEEI 120
           TAREVKQIRREISRKSKWVKMLGEWDTYKNSRKLIDRAYQGIPMNIRGPMWSVLLNIEEI
Sbjct: 61  TAREVKQIRREISRKSKWVKMLGEWDTYKNSRKLIDRAYQGIPMNIRGPMWSVLLNIEEI 120

Query: 121 KLKNPGRYQIMKEKGKRSSEHIQQMDLDVSGTLRRHIFFRDRYGTNLLCISGRWGGPQKD 180
           KLKNPGRYQIMKEKGKRSSEHIQQMDLDVSGTLRRHIFFRDRYGTNLLCISGRWGGPQKD
Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQQMDLDVSGTLRRHIFFRDRYGTNLLCISGRWGGPQKD 180

Query: 181 PAPPKRLTKTSRCGPWARFWNRFVDAWARDDDTVLKHLRASMKKLTRKQGDLPPPAKPEQ 240
           PAPPKRLTKTSRCGPWARFWNRFVDAWARDDDTVLKHLRASMKKLTRKQGDLPPPAKPEQ
Sbjct: 181 PAPPKRLTKTSRCGPWARFWNRFVDAWARDDDTVLKHLRASMKKLTRKQGDLPPPAKPEQ 240

Query: 241 GSSASRPVPASRGGKTLCKGDRQAPPGPPARFPWPIWSASPPRAPRSSTPCPGGAVREDT 300
           GSSASRPVPASRGGKTLCKGDRQAPPGPPARFPWPIWSASPPRAPRSSTPCPGGAVREDT
Sbjct: 241 GSSASRPVPASRGGKTLCKGDRQAPPGPPARFPWPIWSASPPRAPRSSTPCPGGAVREDT 300

Query: 301 YPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVGDPWFRRYDFRQSCWVRAISQ 360
           YPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVGDPWFRRYDFRQSCWVRAISQ
Sbjct: 301 YPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVGDPWFRRYDFRQSCWVRAISQ 360

Query: 361 EDQPATCWQAEHPAERVRSAFSAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQF 420
           EDQPATCWQAEHPAERVRSAFSAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQF
Sbjct: 361 EDQPATCWQAEHPAERVRSAFSAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQF 420

Query: 421 PPGF 424
           PPGF
Sbjct: 421 PPGF 424


>gi|226693407 TBC1 domain family, member 3H [Homo sapiens]
          Length = 549

 Score =  495 bits (1275), Expect = e-140
 Identities = 230/240 (95%), Positives = 232/240 (96%)

Query: 185 KRLTKTSRCGPWARFWNRFVDAWARDDDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSA 244
           KRLTKTSRCGPWARF NRFVD WARD+DTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSA
Sbjct: 310 KRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSA 369

Query: 245 SRPVPASRGGKTLCKGDRQAPPGPPARFPWPIWSASPPRAPRSSTPCPGGAVREDTYPVG 304
           SRPVPASRGGKTLCKGDRQAPPGPPARFP PIWSASPPRAPRSSTPCPGGAVREDTYPVG
Sbjct: 370 SRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVG 429

Query: 305 TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVGDPWFRRYDFRQSCWVRAISQEDQP 364
           TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDV  PWFR YDFRQSCWVRAISQEDQ 
Sbjct: 430 TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQL 489

Query: 365 ATCWQAEHPAERVRSAFSAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF 424
           A CWQAEHPAERVRSAF+APSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF
Sbjct: 490 APCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF 549



 Score =  310 bits (794), Expect = 2e-84
 Identities = 143/165 (86%), Positives = 157/165 (95%)

Query: 1   MDVVEVVGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFGSYNNNIDHFGMQHETELPPL 60
           MDVVEV GSWWAQEREDIIMKYEKGH+AGLPEDKGPKPF SYNNN+DH G+ HETELPPL
Sbjct: 1   MDVVEVAGSWWAQEREDIIMKYEKGHQAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60

Query: 61  TAREVKQIRREISRKSKWVKMLGEWDTYKNSRKLIDRAYQGIPMNIRGPMWSVLLNIEEI 120
           TARE KQIRREISRKSKWV MLG+W+ YK+SRKLIDRAY+G+PMNIRGPMWSVLLNIEE+
Sbjct: 61  TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120

Query: 121 KLKNPGRYQIMKEKGKRSSEHIQQMDLDVSGTLRRHIFFRDRYGT 165
           KLKNPGRYQIMKEKGKRSSEHIQ++D D+SGTLR+H+FFRDRYGT
Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGT 165


>gi|183583563 TBC1 domain family, member 3D [Homo sapiens]
          Length = 549

 Score =  495 bits (1275), Expect = e-140
 Identities = 230/240 (95%), Positives = 232/240 (96%)

Query: 185 KRLTKTSRCGPWARFWNRFVDAWARDDDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSA 244
           KRLTKTSRCGPWARF NRFVD WARD+DTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSA
Sbjct: 310 KRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSA 369

Query: 245 SRPVPASRGGKTLCKGDRQAPPGPPARFPWPIWSASPPRAPRSSTPCPGGAVREDTYPVG 304
           SRPVPASRGGKTLCKGDRQAPPGPPARFP PIWSASPPRAPRSSTPCPGGAVREDTYPVG
Sbjct: 370 SRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVG 429

Query: 305 TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVGDPWFRRYDFRQSCWVRAISQEDQP 364
           TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDV  PWFR YDFRQSCWVRAISQEDQ 
Sbjct: 430 TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQL 489

Query: 365 ATCWQAEHPAERVRSAFSAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF 424
           A CWQAEHPAERVRSAF+APSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF
Sbjct: 490 APCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF 549



 Score =  313 bits (802), Expect = 2e-85
 Identities = 146/165 (88%), Positives = 157/165 (95%)

Query: 1   MDVVEVVGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFGSYNNNIDHFGMQHETELPPL 60
           MDVVEV GSWWAQEREDIIMKYEKGHRAGLPEDKGPKPF SYNNN+DH G+ HETELPPL
Sbjct: 1   MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60

Query: 61  TAREVKQIRREISRKSKWVKMLGEWDTYKNSRKLIDRAYQGIPMNIRGPMWSVLLNIEEI 120
           TARE KQIRREISRKSKWV MLG+W+ YK+SRKLIDRAY+G+PMNIRGPMWSVLLNIEE+
Sbjct: 61  TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120

Query: 121 KLKNPGRYQIMKEKGKRSSEHIQQMDLDVSGTLRRHIFFRDRYGT 165
           KLKNPGRYQIMKEKGKRSSEHIQ++D DVSGTLR+HIFFRDRYGT
Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGT 165


>gi|90577185 TBC1 domain family member 3C [Homo sapiens]
          Length = 549

 Score =  495 bits (1275), Expect = e-140
 Identities = 230/240 (95%), Positives = 232/240 (96%)

Query: 185 KRLTKTSRCGPWARFWNRFVDAWARDDDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSA 244
           KRLTKTSRCGPWARF NRFVD WARD+DTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSA
Sbjct: 310 KRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSA 369

Query: 245 SRPVPASRGGKTLCKGDRQAPPGPPARFPWPIWSASPPRAPRSSTPCPGGAVREDTYPVG 304
           SRPVPASRGGKTLCKGDRQAPPGPPARFP PIWSASPPRAPRSSTPCPGGAVREDTYPVG
Sbjct: 370 SRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVG 429

Query: 305 TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVGDPWFRRYDFRQSCWVRAISQEDQP 364
           TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDV  PWFR YDFRQSCWVRAISQEDQ 
Sbjct: 430 TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQL 489

Query: 365 ATCWQAEHPAERVRSAFSAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF 424
           A CWQAEHPAERVRSAF+APSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF
Sbjct: 490 APCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF 549



 Score =  311 bits (798), Expect = 5e-85
 Identities = 144/165 (87%), Positives = 157/165 (95%)

Query: 1   MDVVEVVGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFGSYNNNIDHFGMQHETELPPL 60
           MDVVEV GSWWAQEREDIIMKYEKGHRAGLPEDKGPKPF SYNNN+DH G+ HETELPPL
Sbjct: 1   MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60

Query: 61  TAREVKQIRREISRKSKWVKMLGEWDTYKNSRKLIDRAYQGIPMNIRGPMWSVLLNIEEI 120
           TARE KQIRREISRKSKWV MLG+W+ YK+SRKLIDRAY+G+PMNIRGPMWSVLLNIEE+
Sbjct: 61  TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120

Query: 121 KLKNPGRYQIMKEKGKRSSEHIQQMDLDVSGTLRRHIFFRDRYGT 165
           KLKNPGRYQIMKEKGKRSSEHIQ++D D+SGTLR+H+FFRDRYGT
Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGT 165


>gi|157502205 TBC1 domain family, member 3G [Homo sapiens]
          Length = 549

 Score =  495 bits (1275), Expect = e-140
 Identities = 230/240 (95%), Positives = 232/240 (96%)

Query: 185 KRLTKTSRCGPWARFWNRFVDAWARDDDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSA 244
           KRLTKTSRCGPWARF NRFVD WARD+DTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSA
Sbjct: 310 KRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSA 369

Query: 245 SRPVPASRGGKTLCKGDRQAPPGPPARFPWPIWSASPPRAPRSSTPCPGGAVREDTYPVG 304
           SRPVPASRGGKTLCKGDRQAPPGPPARFP PIWSASPPRAPRSSTPCPGGAVREDTYPVG
Sbjct: 370 SRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVG 429

Query: 305 TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVGDPWFRRYDFRQSCWVRAISQEDQP 364
           TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDV  PWFR YDFRQSCWVRAISQEDQ 
Sbjct: 430 TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQL 489

Query: 365 ATCWQAEHPAERVRSAFSAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF 424
           A CWQAEHPAERVRSAF+APSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF
Sbjct: 490 APCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF 549



 Score =  311 bits (798), Expect = 5e-85
 Identities = 144/165 (87%), Positives = 157/165 (95%)

Query: 1   MDVVEVVGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFGSYNNNIDHFGMQHETELPPL 60
           MDVVEV GSWWAQEREDIIMKYEKGHRAGLPEDKGPKPF SYNNN+DH G+ HETELPPL
Sbjct: 1   MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60

Query: 61  TAREVKQIRREISRKSKWVKMLGEWDTYKNSRKLIDRAYQGIPMNIRGPMWSVLLNIEEI 120
           TARE KQIRREISRKSKWV MLG+W+ YK+SRKLIDRAY+G+PMNIRGPMWSVLLNIEE+
Sbjct: 61  TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120

Query: 121 KLKNPGRYQIMKEKGKRSSEHIQQMDLDVSGTLRRHIFFRDRYGT 165
           KLKNPGRYQIMKEKGKRSSEHIQ++D D+SGTLR+H+FFRDRYGT
Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGT 165


>gi|14149985 TBC1 domain family, member 3F [Homo sapiens]
          Length = 549

 Score =  494 bits (1271), Expect = e-140
 Identities = 229/240 (95%), Positives = 232/240 (96%)

Query: 185 KRLTKTSRCGPWARFWNRFVDAWARDDDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSA 244
           KRLTKTSRCGPWARF NRFVD WARD+DTVLKHLRASMKKLTRK+GDLPPPAKPEQGSSA
Sbjct: 310 KRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSA 369

Query: 245 SRPVPASRGGKTLCKGDRQAPPGPPARFPWPIWSASPPRAPRSSTPCPGGAVREDTYPVG 304
           SRPVPASRGGKTLCKGDRQAPPGPPARFP PIWSASPPRAPRSSTPCPGGAVREDTYPVG
Sbjct: 370 SRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVG 429

Query: 305 TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVGDPWFRRYDFRQSCWVRAISQEDQP 364
           TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDV  PWFR YDFRQSCWVRAISQEDQ 
Sbjct: 430 TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQL 489

Query: 365 ATCWQAEHPAERVRSAFSAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF 424
           A CWQAEHPAERVRSAF+APSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF
Sbjct: 490 APCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF 549



 Score =  310 bits (794), Expect = 2e-84
 Identities = 144/165 (87%), Positives = 156/165 (94%)

Query: 1   MDVVEVVGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFGSYNNNIDHFGMQHETELPPL 60
           MDVVEV GSWWAQEREDIIMKYEKGHRAGLPEDKGPKPF SYNNN+DH G+ HETELPPL
Sbjct: 1   MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60

Query: 61  TAREVKQIRREISRKSKWVKMLGEWDTYKNSRKLIDRAYQGIPMNIRGPMWSVLLNIEEI 120
           TARE KQIRREISRKSKWV MLG+W+ YK+SRKLIDRAY+G+PMNIRGPMWSVLLN EE+
Sbjct: 61  TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEM 120

Query: 121 KLKNPGRYQIMKEKGKRSSEHIQQMDLDVSGTLRRHIFFRDRYGT 165
           KLKNPGRYQIMKEKGK+SSEHIQ++D DVSGTLR+HIFFRDRYGT
Sbjct: 121 KLKNPGRYQIMKEKGKKSSEHIQRIDRDVSGTLRKHIFFRDRYGT 165


>gi|183583565 TBC1 domain family, member 3 [Homo sapiens]
          Length = 549

 Score =  494 bits (1271), Expect = e-140
 Identities = 229/240 (95%), Positives = 232/240 (96%)

Query: 185 KRLTKTSRCGPWARFWNRFVDAWARDDDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSA 244
           KRLTKTSRCGPWARF NRFVD WARD+DTVLKHLRASMKKLTRK+GDLPPPAKPEQGSSA
Sbjct: 310 KRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSA 369

Query: 245 SRPVPASRGGKTLCKGDRQAPPGPPARFPWPIWSASPPRAPRSSTPCPGGAVREDTYPVG 304
           SRPVPASRGGKTLCKGDRQAPPGPPARFP PIWSASPPRAPRSSTPCPGGAVREDTYPVG
Sbjct: 370 SRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVG 429

Query: 305 TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVGDPWFRRYDFRQSCWVRAISQEDQP 364
           TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDV  PWFR YDFRQSCWVRAISQEDQ 
Sbjct: 430 TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQL 489

Query: 365 ATCWQAEHPAERVRSAFSAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF 424
           A CWQAEHPAERVRSAF+APSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF
Sbjct: 490 APCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF 549



 Score =  313 bits (802), Expect = 2e-85
 Identities = 146/165 (88%), Positives = 157/165 (95%)

Query: 1   MDVVEVVGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFGSYNNNIDHFGMQHETELPPL 60
           MDVVEV GSWWAQEREDIIMKYEKGHRAGLPEDKGPKPF SYNNN+DH G+ HETELPPL
Sbjct: 1   MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60

Query: 61  TAREVKQIRREISRKSKWVKMLGEWDTYKNSRKLIDRAYQGIPMNIRGPMWSVLLNIEEI 120
           TARE KQIRREISRKSKWV MLG+W+ YK+SRKLIDRAY+G+PMNIRGPMWSVLLNIEE+
Sbjct: 61  TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120

Query: 121 KLKNPGRYQIMKEKGKRSSEHIQQMDLDVSGTLRRHIFFRDRYGT 165
           KLKNPGRYQIMKEKGKRSSEHIQ++D DVSGTLR+HIFFRDRYGT
Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGT 165


>gi|183583567 TBC1 domain family, member 3E [Homo sapiens]
          Length = 549

 Score =  494 bits (1271), Expect = e-140
 Identities = 229/240 (95%), Positives = 232/240 (96%)

Query: 185 KRLTKTSRCGPWARFWNRFVDAWARDDDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSA 244
           KRLTKTSRCGPWARF NRFVD WARD+DTVLKHLRASMKKLTRK+GDLPPPAKPEQGSSA
Sbjct: 310 KRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSA 369

Query: 245 SRPVPASRGGKTLCKGDRQAPPGPPARFPWPIWSASPPRAPRSSTPCPGGAVREDTYPVG 304
           SRPVPASRGGKTLCKGDRQAPPGPPARFP PIWSASPPRAPRSSTPCPGGAVREDTYPVG
Sbjct: 370 SRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVG 429

Query: 305 TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVGDPWFRRYDFRQSCWVRAISQEDQP 364
           TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDV  PWFR YDFRQSCWVRAISQEDQ 
Sbjct: 430 TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQL 489

Query: 365 ATCWQAEHPAERVRSAFSAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF 424
           A CWQAEHPAERVRSAF+APSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF
Sbjct: 490 APCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF 549



 Score =  313 bits (802), Expect = 2e-85
 Identities = 146/165 (88%), Positives = 157/165 (95%)

Query: 1   MDVVEVVGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFGSYNNNIDHFGMQHETELPPL 60
           MDVVEV GSWWAQEREDIIMKYEKGHRAGLPEDKGPKPF SYNNN+DH G+ HETELPPL
Sbjct: 1   MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60

Query: 61  TAREVKQIRREISRKSKWVKMLGEWDTYKNSRKLIDRAYQGIPMNIRGPMWSVLLNIEEI 120
           TARE KQIRREISRKSKWV MLG+W+ YK+SRKLIDRAY+G+PMNIRGPMWSVLLNIEE+
Sbjct: 61  TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120

Query: 121 KLKNPGRYQIMKEKGKRSSEHIQQMDLDVSGTLRRHIFFRDRYGT 165
           KLKNPGRYQIMKEKGKRSSEHIQ++D DVSGTLR+HIFFRDRYGT
Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGT 165


>gi|149999613 TBC1 domain family, member 3B [Homo sapiens]
          Length = 549

 Score =  491 bits (1264), Expect = e-139
 Identities = 229/240 (95%), Positives = 231/240 (96%)

Query: 185 KRLTKTSRCGPWARFWNRFVDAWARDDDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSA 244
           KRLTKTSRCGPWARF NRFVD WARD+DTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSA
Sbjct: 310 KRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSA 369

Query: 245 SRPVPASRGGKTLCKGDRQAPPGPPARFPWPIWSASPPRAPRSSTPCPGGAVREDTYPVG 304
           SRPVPASRGGKTLCKGDRQAPPGPPARFP PIWSASPPRAPRSSTPCPGGAVREDTYPVG
Sbjct: 370 SRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVG 429

Query: 305 TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVGDPWFRRYDFRQSCWVRAISQEDQP 364
           TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDV  PWFR YDFRQSCWVRAISQEDQ 
Sbjct: 430 TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQL 489

Query: 365 ATCWQAEHPAERVRSAFSAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF 424
           A CWQAEHPAERVRSAF+APSTDSDQGTPFRARDEQQ APTSGPCLCGLHLESSQFPPGF
Sbjct: 490 APCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQYAPTSGPCLCGLHLESSQFPPGF 549



 Score =  311 bits (798), Expect = 5e-85
 Identities = 144/165 (87%), Positives = 157/165 (95%)

Query: 1   MDVVEVVGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFGSYNNNIDHFGMQHETELPPL 60
           MDVVEV GSWWAQEREDIIMKYEKGHRAGLPEDKGPKPF SYNNN+DH G+ HETELPPL
Sbjct: 1   MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPL 60

Query: 61  TAREVKQIRREISRKSKWVKMLGEWDTYKNSRKLIDRAYQGIPMNIRGPMWSVLLNIEEI 120
           TARE KQIRREISRKSKWV MLG+W+ YK+SRKLIDRAY+G+PMNIRGPMWSVLLNIEE+
Sbjct: 61  TAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEM 120

Query: 121 KLKNPGRYQIMKEKGKRSSEHIQQMDLDVSGTLRRHIFFRDRYGT 165
           KLKNPGRYQIMKEKGKRSSEHIQ++D D+SGTLR+H+FFRDRYGT
Sbjct: 121 KLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGT 165


>gi|109638751 ubiquitin specific protease 6 [Homo sapiens]
          Length = 1406

 Score =  332 bits (851), Expect = 4e-91
 Identities = 165/221 (74%), Positives = 174/221 (78%), Gaps = 2/221 (0%)

Query: 185 KRLTKTSRCGPWARFWNRFVDAWARDDDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSA 244
           KRL KTSRCG WAR  N+F D WA +DDTVLKHLRAS KKLTRKQGDLPPPAK EQGS A
Sbjct: 309 KRLMKTSRCGLWARLRNQFFDTWAMNDDTVLKHLRASTKKLTRKQGDLPPPAKREQGSLA 368

Query: 245 SRPVPASRGGKTLCKGDRQAPPGPPARFPWPIWSASPPRAPRSSTPCPGGAVREDTYPVG 304
            RPVPASRGGKTLCKG RQAPPGPPA+F  PI SASPP A R STPCPGGAVREDTYPVG
Sbjct: 369 PRPVPASRGGKTLCKGYRQAPPGPPAQFQRPICSASPPWASRFSTPCPGGAVREDTYPVG 428

Query: 305 TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVGDPWFRRYDFRQSCWVRAISQEDQP 364
           TQGVPS ALAQGGPQGSWRFL+W SMPRLPTDLD+G PWF  YDF  SCWVRAISQEDQ 
Sbjct: 429 TQGVPSLALAQGGPQGSWRFLEWKSMPRLPTDLDIGGPWFPHYDFEWSCWVRAISQEDQL 488

Query: 365 ATCWQAEHPAERVRSAFSAPSTDSDQGTPFRARDEQQCAPT 405
           ATCWQAEH  E      S P   S   T   ++ ++Q  PT
Sbjct: 489 ATCWQAEHCGEVHNKDMSWPEEMS--FTANSSKIDRQKVPT 527



 Score =  261 bits (666), Expect = 1e-69
 Identities = 123/164 (75%), Positives = 145/164 (88%), Gaps = 1/164 (0%)

Query: 1   MDVVEVVGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFGSYNNNIDHFGMQHETELPPL 60
           MD+VE   S  AQER+DI+MKY+KGHRAGLPEDKGP+P G  N++ID FG+ HETELPP+
Sbjct: 1   MDMVENADSLQAQERKDILMKYDKGHRAGLPEDKGPEPVG-INSSIDRFGILHETELPPV 59

Query: 61  TAREVKQIRREISRKSKWVKMLGEWDTYKNSRKLIDRAYQGIPMNIRGPMWSVLLNIEEI 120
           TARE K+IRRE++R SKW++MLGEW+TYK+S KLIDR Y+GIPMNIRGP+WSVLLNI+EI
Sbjct: 60  TAREAKKIRREMTRTSKWMEMLGEWETYKHSSKLIDRVYKGIPMNIRGPVWSVLLNIQEI 119

Query: 121 KLKNPGRYQIMKEKGKRSSEHIQQMDLDVSGTLRRHIFFRDRYG 164
           KLKNPGRYQIMKE+GKRSSEHI  +DLDV  TLR H+FFRDRYG
Sbjct: 120 KLKNPGRYQIMKERGKRSSEHIHHIDLDVRTTLRNHVFFRDRYG 163


>gi|239745813 PREDICTED: hypothetical protein XP_002343595 [Homo
           sapiens]
          Length = 279

 Score =  179 bits (455), Expect = 3e-45
 Identities = 101/189 (53%), Positives = 114/189 (60%), Gaps = 24/189 (12%)

Query: 185 KRLTKTSRCGPWARFWNRFVDAWARDDDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSA 244
           K L K SR G WARF ++F   WA D D VL+HL+AS+             +KP+QGSSA
Sbjct: 110 KHLMKASRSGLWARFQDQFPQTWALDSDAVLRHLQASVL------------SKPKQGSSA 157

Query: 245 SRPVPASR-GGKTLCKGDRQAPPGPPARFPWPIWSASPPRAPRSSTPCPGGAVREDTYPV 303
            RP  AS  G KTLCKG RQAPPGP A F   IWSASPP  P   TPCP          V
Sbjct: 158 PRPELASPCGRKTLCKGSRQAPPGPQAHFQQCIWSASPPWVPLPFTPCP--------VLV 209

Query: 304 G-TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVGDPWFRRYDFRQSCWVRAISQ-- 360
           G +QGVP  A AQGGP+ SWR+LQWNS+P+LP D DV  PWF  YDF Q CW R  S+  
Sbjct: 210 GLSQGVPRLAPAQGGPRVSWRYLQWNSLPQLPMDSDVVSPWFPHYDFEQGCWARVPSKCV 269

Query: 361 EDQPATCWQ 369
            D P T  Q
Sbjct: 270 LDSPGTMGQ 278


>gi|239756790 PREDICTED: similar to hCG1991532 [Homo sapiens]
          Length = 167

 Score =  177 bits (448), Expect = 2e-44
 Identities = 99/185 (53%), Positives = 112/185 (60%), Gaps = 24/185 (12%)

Query: 189 KTSRCGPWARFWNRFVDAWARDDDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPV 248
           K SR G WARF ++F   WA D D VL+HL+AS+             +KP+QGSSA RP 
Sbjct: 2   KASRSGLWARFQDQFPQTWALDSDAVLRHLQASVL------------SKPKQGSSAPRPE 49

Query: 249 PASR-GGKTLCKGDRQAPPGPPARFPWPIWSASPPRAPRSSTPCPGGAVREDTYPVG-TQ 306
            AS  G KTLCKG RQAPPGP A F   IWSASPP  P   TPCP          VG +Q
Sbjct: 50  LASPCGRKTLCKGSRQAPPGPQAHFQQRIWSASPPWVPLPFTPCP--------VLVGLSQ 101

Query: 307 GVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVGDPWFRRYDFRQSCWVRAISQ--EDQP 364
           GVP  A AQGGP+ SWR+LQWNS+P+LP D DV  PWF  YDF Q CW R  S+   D P
Sbjct: 102 GVPRLAPAQGGPRVSWRYLQWNSLPQLPMDSDVVSPWFPHYDFEQGCWARVPSKCVLDSP 161

Query: 365 ATCWQ 369
            T  Q
Sbjct: 162 GTMGQ 166


>gi|239751314 PREDICTED: hypothetical protein XP_002347802 [Homo
           sapiens]
          Length = 179

 Score =  149 bits (377), Expect = 4e-36
 Identities = 82/141 (58%), Positives = 89/141 (63%), Gaps = 12/141 (8%)

Query: 233 PPPAKPEQGSSASRPVPASR-GGKTLCKGDRQAPPGPPARFPWPIWSASPPRAPRSSTPC 291
           P  AKP+QGSSA RP  AS  G KTLCKG RQAPPGP A F   IWSASPP  P   TPC
Sbjct: 46  PEEAKPKQGSSAPRPELASPCGRKTLCKGSRQAPPGPQAHFQQCIWSASPPWVPLPFTPC 105

Query: 292 PGGAVREDTYPVG-TQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVGDPWFRRYDFR 350
           P          VG +QGVP  A AQGGP+ SWR+LQWNS+P+LP D DV  PWF  YDF 
Sbjct: 106 P--------VLVGLSQGVPRLAPAQGGPRVSWRYLQWNSLPQLPMDSDVVSPWFPHYDFE 157

Query: 351 QSCWVRAISQ--EDQPATCWQ 369
           Q CW R  S+   D P T  Q
Sbjct: 158 QGCWARVPSKCVLDSPGTMGQ 178


>gi|148235002 TBC1 domain family, member 26 [Homo sapiens]
          Length = 250

 Score =  149 bits (375), Expect = 6e-36
 Identities = 75/149 (50%), Positives = 103/149 (69%), Gaps = 5/149 (3%)

Query: 18  IIMKYEKGHRAGLPEDKGPKPFG--SYNNNIDHFGMQHETELPPLTAREVKQIRREISRK 75
           II KYE+GHRAG   D G +      Y NN+   G+ HE ELP ++A EVKQ R+E  R 
Sbjct: 19  IITKYEQGHRAGAAVDLGHEQVDVRKYTNNL---GIVHEMELPRVSALEVKQRRKESKRT 75

Query: 76  SKWVKMLGEWDTYKNSRKLIDRAYQGIPMNIRGPMWSVLLNIEEIKLKNPGRYQIMKEKG 135
           +KW KML +W  Y++++KL  R Y+ IP+ +RG  WS+LL+I+ IK +NPG+Y++MKEKG
Sbjct: 76  NKWQKMLADWTKYRSTKKLSQRVYKVIPLAVRGRAWSLLLDIDRIKSQNPGKYKVMKEKG 135

Query: 136 KRSSEHIQQMDLDVSGTLRRHIFFRDRYG 164
           KRSS  I  + LDVS TL++H+ F  R+G
Sbjct: 136 KRSSRIIHCIQLDVSHTLQKHMMFIQRFG 164


>gi|239756750 PREDICTED: similar to TBC1 domain family, member 28
           [Homo sapiens]
          Length = 234

 Score =  140 bits (354), Expect = 2e-33
 Identities = 73/149 (48%), Positives = 102/149 (68%), Gaps = 5/149 (3%)

Query: 18  IIMKYEKGHRAGLPEDKGPKPFG--SYNNNIDHFGMQHETELPPLTAREVKQIRREISRK 75
           II KYE+GHRAG   D G +      Y NN+   G+ HE ELP ++A EVKQ R+E  R 
Sbjct: 43  IITKYEQGHRAGAAVDLGHEQVDVRKYTNNL---GIVHEMELPHVSALEVKQRRKESKRT 99

Query: 76  SKWVKMLGEWDTYKNSRKLIDRAYQGIPMNIRGPMWSVLLNIEEIKLKNPGRYQIMKEKG 135
           +KW KML +W  Y++++KL  R  + IP+ +RG   S+LL+I++IK +NPG+Y++MKEKG
Sbjct: 100 NKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVMKEKG 159

Query: 136 KRSSEHIQQMDLDVSGTLRRHIFFRDRYG 164
           KRSS  I  + LDVS TL++H+ F  R+G
Sbjct: 160 KRSSRIIHCIQLDVSHTLQKHMMFIQRFG 188


>gi|151108489 TBC1 domain family, member 28 [Homo sapiens]
          Length = 210

 Score =  140 bits (354), Expect = 2e-33
 Identities = 73/149 (48%), Positives = 102/149 (68%), Gaps = 5/149 (3%)

Query: 18  IIMKYEKGHRAGLPEDKGPKPFG--SYNNNIDHFGMQHETELPPLTAREVKQIRREISRK 75
           II KYE+GHRAG   D G +      Y NN+   G+ HE ELP ++A EVKQ R+E  R 
Sbjct: 19  IITKYEQGHRAGAAVDLGHEQVDVRKYTNNL---GIVHEMELPRVSALEVKQRRKESKRT 75

Query: 76  SKWVKMLGEWDTYKNSRKLIDRAYQGIPMNIRGPMWSVLLNIEEIKLKNPGRYQIMKEKG 135
           +KW KML +W  Y++++KL  R  + IP+ +RG   S+LL+I++IK +NPG+Y++MKEKG
Sbjct: 76  NKWQKMLADWTKYRSTKKLSQRVCKVIPLAVRGRALSLLLDIDKIKSQNPGKYKVMKEKG 135

Query: 136 KRSSEHIQQMDLDVSGTLRRHIFFRDRYG 164
           KRSS  I  + LDVS TL++H+ F  R+G
Sbjct: 136 KRSSRIIHCIQLDVSHTLQKHMMFIQRFG 164


>gi|7661864 USP6 N-terminal like isoform 1 [Homo sapiens]
          Length = 828

 Score =  121 bits (303), Expect = 1e-27
 Identities = 63/153 (41%), Positives = 88/153 (57%), Gaps = 1/153 (0%)

Query: 12  AQEREDIIMKYEKGHRAGLPEDKGPKPFGSYNNNIDHFGMQHETELPPLTAREVKQIRRE 71
           AQER +I+ KY++G      E      +  Y    D FG  HE ELP       +Q   E
Sbjct: 12  AQERAEIVAKYDRGREGAEIEPWEDADYLVYKVT-DRFGFLHEEELPDHNVAVERQKHLE 70

Query: 72  ISRKSKWVKMLGEWDTYKNSRKLIDRAYQGIPMNIRGPMWSVLLNIEEIKLKNPGRYQIM 131
           I R +KW+KML  W+ YKN+ K   R Y+GIP+ +RG +W++LL I ++K +    Y  +
Sbjct: 71  IERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKL 130

Query: 132 KEKGKRSSEHIQQMDLDVSGTLRRHIFFRDRYG 164
           K + +  S  I+Q+DLDV+ T R HI FRDRYG
Sbjct: 131 KHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYG 163



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 30/107 (28%), Positives = 41/107 (38%), Gaps = 16/107 (14%)

Query: 210 DDDTVLKHLRASMKKLTRKQGDLPPPAK----PEQGSSASRPVPASRGGKTLCKGDRQAP 265
           +DD V++ L+ SM +L R + DLP P K    P++      P   S G   L  G R   
Sbjct: 334 EDDFVIEQLQISMTELKRAKLDLPEPGKEDEYPKKPLGQLPPELQSWGVHHLSNGQRSV- 392

Query: 266 PGPPARFPWPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPA 312
            G P          SP  + R  +  P        +P    G P  A
Sbjct: 393 -GRP----------SPLASGRRESGAPHRRHEHSPHPQSRTGTPERA 428


>gi|122937432 USP6 N-terminal like isoform 2 [Homo sapiens]
          Length = 845

 Score =  121 bits (303), Expect = 1e-27
 Identities = 63/153 (41%), Positives = 88/153 (57%), Gaps = 1/153 (0%)

Query: 12  AQEREDIIMKYEKGHRAGLPEDKGPKPFGSYNNNIDHFGMQHETELPPLTAREVKQIRRE 71
           AQER +I+ KY++G      E      +  Y    D FG  HE ELP       +Q   E
Sbjct: 29  AQERAEIVAKYDRGREGAEIEPWEDADYLVYKVT-DRFGFLHEEELPDHNVAVERQKHLE 87

Query: 72  ISRKSKWVKMLGEWDTYKNSRKLIDRAYQGIPMNIRGPMWSVLLNIEEIKLKNPGRYQIM 131
           I R +KW+KML  W+ YKN+ K   R Y+GIP+ +RG +W++LL I ++K +    Y  +
Sbjct: 88  IERTTKWLKMLKGWEKYKNTEKFHRRIYKGIPLQLRGEVWALLLEIPKMKEETRDLYSKL 147

Query: 132 KEKGKRSSEHIQQMDLDVSGTLRRHIFFRDRYG 164
           K + +  S  I+Q+DLDV+ T R HI FRDRYG
Sbjct: 148 KHRARGCSPDIRQIDLDVNRTFRDHIMFRDRYG 180



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 30/107 (28%), Positives = 41/107 (38%), Gaps = 16/107 (14%)

Query: 210 DDDTVLKHLRASMKKLTRKQGDLPPPAK----PEQGSSASRPVPASRGGKTLCKGDRQAP 265
           +DD V++ L+ SM +L R + DLP P K    P++      P   S G   L  G R   
Sbjct: 351 EDDFVIEQLQISMTELKRAKLDLPEPGKEDEYPKKPLGQLPPELQSWGVHHLSNGQRSV- 409

Query: 266 PGPPARFPWPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPA 312
            G P          SP  + R  +  P        +P    G P  A
Sbjct: 410 -GRP----------SPLASGRRESGAPHRRHEHSPHPQSRTGTPERA 445


>gi|241982780 programmed cell death 6 interacting protein isoform 2
           [Homo sapiens]
          Length = 873

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 39/124 (31%), Positives = 54/124 (43%), Gaps = 10/124 (8%)

Query: 198 RFWNRFVD---AWARDDDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGG 254
           RF N+  D   A   + D +LK L+ S+ +       +P PA     +    P P +   
Sbjct: 691 RFQNKCSDIVFARKTERDELLKDLQQSIAR-EPSAPSIPTPAYQSSPAGGHAPTPPTPAP 749

Query: 255 KTLCKGDRQAPPGPPARFPWPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALA 314
           +T+        P PPAR P P+  A+  RAP ++ P P GA      P  T G   P  A
Sbjct: 750 RTM----PPTKPQPPARPPPPVLPAN--RAPSATAPSPVGAGTAAPAPSQTPGSAPPPQA 803

Query: 315 QGGP 318
           QG P
Sbjct: 804 QGPP 807


>gi|22027538 programmed cell death 6 interacting protein isoform 1
           [Homo sapiens]
          Length = 868

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 39/124 (31%), Positives = 54/124 (43%), Gaps = 10/124 (8%)

Query: 198 RFWNRFVD---AWARDDDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGG 254
           RF N+  D   A   + D +LK L+ S+ +       +P PA     +    P P +   
Sbjct: 686 RFQNKCSDIVFARKTERDELLKDLQQSIAR-EPSAPSIPTPAYQSSPAGGHAPTPPTPAP 744

Query: 255 KTLCKGDRQAPPGPPARFPWPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALA 314
           +T+        P PPAR P P+  A+  RAP ++ P P GA      P  T G   P  A
Sbjct: 745 RTM----PPTKPQPPARPPPPVLPAN--RAPSATAPSPVGAGTAAPAPSQTPGSAPPPQA 798

Query: 315 QGGP 318
           QG P
Sbjct: 799 QGPP 802


>gi|239756746 PREDICTED: TBC1 domain family, member 27 [Homo
           sapiens]
          Length = 339

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 77/272 (28%), Positives = 118/272 (43%), Gaps = 55/272 (20%)

Query: 18  IIMKYEKGHRAGLPEDKGP--KPFGSYNNNIDHFGMQHETELPPLTAREVKQIRREISRK 75
           II KYE+G +A  P   G   +P  S N+ + H           LTA+EV    R++SR 
Sbjct: 19  IITKYEQGPKAQDPASMGRCRRPGSSANSIMAH-----------LTAKEVGY-HRDLSRN 66

Query: 76  SKWVKMLGEWDTYKNSRKLIDRAYQGIPMNIRGPMWSVLLNIEEIKLKNPGRYQIMKEKG 135
           +  +  L E D +      +  +  G P   +  +  +L + E++  K+  +  IM++ G
Sbjct: 67  TAVLLYLPEEDAF-----WVAGSAAGRPNTAQ--LRKLLSHQEQVLHKSFPK--IMRQLG 117

Query: 136 KRSSEHIQQMDLDVSGTLRRHIF--FRD--RYGTNL-----LCISGRWGGPQKDPAPPK- 185
           K          L + G++   +   F D   +G  L     L + G         A  K 
Sbjct: 118 KEG--------LCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAHASFKI 169

Query: 186 ---RLTKTSRCGPWARFWNRFVDAWARDDDTVLKHLRASMKKLTRKQGDLPPPAKPEQGS 242
               L K S    W  F  R   +WA +D++VL++L+ SMK+LT+K  DLP P    Q  
Sbjct: 170 HREHLMKLSWSTVW-EFQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPSPESLLQ-- 226

Query: 243 SASRPVPA----SRGGKTLC----KGDRQAPP 266
           +A R   A    S+ GK  C     GD +A P
Sbjct: 227 NAHRCTIAWGLQSKAGKNSCTSRASGDFRAHP 258


>gi|239745731 PREDICTED: TBC1 domain family, member 27 [Homo
           sapiens]
          Length = 339

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 74/270 (27%), Positives = 115/270 (42%), Gaps = 51/270 (18%)

Query: 18  IIMKYEKGHRAGLPEDKGP--KPFGSYNNNIDHFGMQHETELPPLTAREVKQIRREISRK 75
           II KYE+G +A  P   G   +P  S N+ + H           LTA+EV    R++SR 
Sbjct: 19  IITKYEQGPKAQDPASMGRCRRPGSSANSIMAH-----------LTAKEVGY-HRDLSRN 66

Query: 76  SKWVKMLGEWDTYKNSRKLIDRAYQGIPMNIRGPMWSVLLNIEEIKLKNPGRYQIMKEKG 135
           +  +  L E D +      +  +  G P   +  +  +L + E++  K+  +  IM++ G
Sbjct: 67  TAVLLYLPEEDAF-----WVAGSAAGRPNTAQ--LRKLLSHQEQVLHKSFPK--IMRQLG 117

Query: 136 KRSSEHIQQMDLDVSGTLRRHIF--FRD--RYGTNL-----LCISGRWGGPQKDPAPPK- 185
           K          L + G++   +   F D   +G  L     L + G         A  K 
Sbjct: 118 KEG--------LCIEGSMLTRLLQCFLDGKSFGLTLRLWDVLILEGEQVLTAMAHASFKI 169

Query: 186 ---RLTKTSRCGPWARFWNRFVDAWARDDDTVLKHLRASMKKLTRKQGDLPPPAKPEQGS 242
               L K S    W  F  R   +WA +D++VL++L+ SMK+LT+K  DLP P    Q +
Sbjct: 170 HREHLMKLSWSTVW-EFQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPSPESLLQNA 228

Query: 243 SASRPV--PASRGGKTLC----KGDRQAPP 266
                     S+ GK  C     GD +A P
Sbjct: 229 HCCTIAWGLQSKAGKNSCTSRASGDFRAHP 258


>gi|167614488 TBC1 domain family, member 10B [Homo sapiens]
          Length = 808

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 26/93 (27%), Positives = 47/93 (50%), Gaps = 3/93 (3%)

Query: 74  RKSKWVKMLGEWDTYKNSR--KLIDRAYQGIPMNIRGPMWSVLLNIEEIKLKNPGRYQIM 131
           R+ KW+ M   WD + + R  K+  R  +GIP ++R   W  L N +E+  +NPG+++ +
Sbjct: 331 RELKWLDMFSNWDKWLSRRFQKVKLRCRKGIPSSLRAKAWQYLSNSKELLEQNPGKFEEL 390

Query: 132 KEKGKRSSEHIQQMDLDVSGTLRRHIFFRDRYG 164
            E+     + +  ++ D+      H  F  R G
Sbjct: 391 -ERAPGDPKWLDVIEKDLHRQFPFHEMFAARGG 422


>gi|239751241 PREDICTED: TBC1 domain family, member 27 [Homo
           sapiens]
          Length = 617

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 28/80 (35%), Positives = 41/80 (51%), Gaps = 9/80 (11%)

Query: 196 WARFWN---RFVDAWARDDDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPV--PA 250
           W+  W    R   +WA +D++VL++L+ SMK+LT+K  DLP P    Q +          
Sbjct: 309 WSTVWEFQERLSQSWALEDNSVLRNLQTSMKELTKKHWDLPSPESLLQNAHCCTIAWGLQ 368

Query: 251 SRGGKTLC----KGDRQAPP 266
           S+ GK  C     GD +A P
Sbjct: 369 SKAGKNSCTSRASGDFRAHP 388


>gi|13994322 TBC1 domain family, member 10A [Homo sapiens]
          Length = 508

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 21/57 (36%), Positives = 33/57 (57%), Gaps = 2/57 (3%)

Query: 74  RKSKWVKMLGEWDTY--KNSRKLIDRAYQGIPMNIRGPMWSVLLNIEEIKLKNPGRY 128
           R+SKW+ ML  WD +  K  +K+  R  +GIP ++RG  W  L   +    +NPG++
Sbjct: 82  RESKWLDMLNNWDKWMAKKHKKIRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKF 138


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 52/212 (24%), Positives = 73/212 (34%), Gaps = 37/212 (17%)

Query: 221 SMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGGKTLCKG-DRQAPPGPPARFPWPIWSA 279
           ++K   R+Q   PPP  P +G     P P    G        R APP PP+R P      
Sbjct: 267 AVKNELRRQA--PPPPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPP 324

Query: 280 SPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSM--------- 330
            PP  P  + P P        YP     +PS A   G P      L    +         
Sbjct: 325 PPPSRPSVAVPPP---PPNRMYPPPPPALPSSA-PSGPPPPPPSVLGVGPVAPPPPPPPP 380

Query: 331 --------PRLPTDLD------VGDPWFRRYDFRQSCWVRAISQEDQPATCWQAEHPAER 376
                   P LP+D D       G+        R+   ++ + Q  +P +C   +   ++
Sbjct: 381 PPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLKKVEQNSRPVSCSGRDALLDQ 440

Query: 377 VRSAFSAPS-TDSDQGTPFRARDEQQCAPTSG 407
           +R      S  D  + TP         APTSG
Sbjct: 441 IRQGIQLKSVADGQESTP------PTPAPTSG 466


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 28/74 (37%), Positives = 34/74 (45%), Gaps = 5/74 (6%)

Query: 230 GDLPPPAKPEQGSSASRPVPASRGGKTL--CKGDRQAPPGPPARFPWPIWSASPPRAPRS 287
           G  PPP  P    +AS PVPA    + L    G    PP PP   P P+ +  PP+    
Sbjct: 805 GATPPPIAPTGPPTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPV-TLPPPQLVPE 863

Query: 288 STPCPGG--AVRED 299
            TP  GG  A+ ED
Sbjct: 864 GTPGGGGPPALEED 877


>gi|156616290 collagen type VI alpha 6 [Homo sapiens]
          Length = 2263

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 39/123 (31%), Positives = 44/123 (35%), Gaps = 32/123 (26%)

Query: 225  LTRKQGDLPPPAKP-------EQGSSASRPVPASRGGKTLCKGDRQAPP----------- 266
            L  +QGD   P +         QGS   R  P  RG K L +GD  AP            
Sbjct: 1468 LNGEQGDNGLPGRKGEKGDEGSQGSPGKRGTPGDRGAKGL-RGDPGAPGVDSSIEGPTGL 1526

Query: 267  ----GPPARFPWPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSP-----ALAQGG 317
                G   R  WP     PP  P S         R  T P GT G+P P     +L   G
Sbjct: 1527 KGERGRQGRRGWP----GPPGTPGSRRKTAAHGRRGHTGPQGTAGIPGPDGLEGSLGLKG 1582

Query: 318  PQG 320
            PQG
Sbjct: 1583 PQG 1585


>gi|157785645 SPEG complex locus [Homo sapiens]
          Length = 3267

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 59/214 (27%), Positives = 84/214 (39%), Gaps = 46/214 (21%)

Query: 217 HLRASMKKLTRKQGDLPP---------PAKPEQGSSASRPVPASRGGKTLCKGDRQAPPG 267
           H+      L R++ DL P         PA+P    SA  P P+ R GK       ++PPG
Sbjct: 271 HVSVPQSGLRREEPDLQPQLASEAPRRPAQPPPSKSALLPPPSPRVGK-------RSPPG 323

Query: 268 PPARFPWPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPS----PAL---AQGGPQ- 319
           PPA+       A+ P +P   T  P   + EDT     +G  S    P+L   A+  PQ 
Sbjct: 324 PPAQ------PAATPTSPHRRTQEP--VLPEDTTTEEKRGKKSKSSGPSLAGTAESRPQT 375

Query: 320 ----GSWRFLQWNSMPRLPTDLDVGDPWFRRYDFRQSCWVRAISQEDQPATCWQAEHPAE 375
                S R       PRL   +  G     +  F +    R++ + D P        P  
Sbjct: 376 PLSEASGRLSALGRSPRL---VRAGSRILDKLQFFEE-RRRSLERSDSPPA---PLRPWV 428

Query: 376 RVRSAFSAPSTDSDQGTPF---RARDEQQCAPTS 406
            +R A S     S++G P+    A  E+  AP S
Sbjct: 429 PLRKARSLEQPKSERGAPWGTPGASQEELRAPGS 462


>gi|38348348 TBC1 domain family, member 10C [Homo sapiens]
          Length = 446

 Score = 39.3 bits (90), Expect = 0.007
 Identities = 27/104 (25%), Positives = 44/104 (42%), Gaps = 8/104 (7%)

Query: 32  EDKGPKPFGSYNNNIDHFGMQHETELPPLTAREVKQIRREISRKSKWVKMLGEWDTYKNS 91
           E  GP P+       D +G    +   P        + R+  R+ KWV+M   W+   + 
Sbjct: 27  ELSGPGPY----RQADRYGFIGGSSAEPGPGHPPADLIRQ--REMKWVEMTSHWEKTMSR 80

Query: 92  R--KLIDRAYQGIPMNIRGPMWSVLLNIEEIKLKNPGRYQIMKE 133
           R  K+  +  +GIP  +R   W +L      +  +PG YQ + E
Sbjct: 81  RYKKVKMQCRKGIPSALRARCWPLLCGAHVCQKNSPGTYQELAE 124


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.449 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,834,318
Number of Sequences: 37866
Number of extensions: 1301425
Number of successful extensions: 7014
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 83
Number of HSP's successfully gapped in prelim test: 466
Number of HSP's that attempted gapping in prelim test: 5944
Number of HSP's gapped (non-prelim): 1390
length of query: 424
length of database: 18,247,518
effective HSP length: 105
effective length of query: 319
effective length of database: 14,271,588
effective search space: 4552636572
effective search space used: 4552636572
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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