Guide to the Human Genome
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Search of human proteins with 119943102

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|119943102 CREB binding protein isoform b [Homo sapiens]
         (2404 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|119943102 CREB binding protein isoform b [Homo sapiens]           4921   0.0  
gi|119943104 CREB binding protein isoform a [Homo sapiens]           4900   0.0  
gi|50345997 E1A binding protein p300 [Homo sapiens]                  2697   0.0  
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...   102   6e-21
gi|7657218 bromodomain-containing protein 4 isoform short [Homo ...    96   6e-19
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    96   6e-19
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]       95   7e-19
gi|110347429 mediator complex subunit 12 [Homo sapiens]                95   9e-19
gi|55750053 atrophin-1 [Homo sapiens]                                  93   4e-18
gi|55750041 atrophin-1 [Homo sapiens]                                  93   4e-18
gi|11067749 bromodomain containing protein 3 [Homo sapiens]            92   6e-18
gi|164419758 bromodomain containing 2 [Homo sapiens]                   91   1e-17
gi|4826806 bromodomain containing 2 [Homo sapiens]                     91   1e-17
gi|33286444 mastermind-like 2 [Homo sapiens]                           87   3e-16
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]       86   4e-16
gi|47132519 Ras association and pleckstrin homology domains 1 is...    85   1e-15
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    84   2e-15
gi|34996489 pleckstrin homology domain interacting protein [Homo...    84   2e-15
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s...    82   5e-15
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]              82   5e-15
gi|38158015 mastermind-like 3 [Homo sapiens]                           82   5e-15
gi|116284392 mucin 2 precursor [Homo sapiens]                          81   1e-14
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             80   2e-14
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   80   2e-14
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   80   2e-14
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   80   2e-14
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    80   2e-14
gi|56549696 E1A binding protein p400 [Homo sapiens]                    80   2e-14
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    80   2e-14
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    79   7e-14

>gi|119943102 CREB binding protein isoform b [Homo sapiens]
          Length = 2404

 Score = 4921 bits (12764), Expect = 0.0
 Identities = 2404/2404 (100%), Positives = 2404/2404 (100%)

Query: 1    MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV 60
            MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
Sbjct: 1    MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV 60

Query: 61   PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK 120
            PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
Sbjct: 61   PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK 120

Query: 121  SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN 180
            SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
Sbjct: 121  SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN 180

Query: 181  FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA 240
            FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
Sbjct: 181  FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA 240

Query: 241  ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK 300
            ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
Sbjct: 241  ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK 300

Query: 301  QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL 360
            QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
Sbjct: 301  QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL 360

Query: 361  LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQAILGSPASGIQNTIG 420
            LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQAILGSPASGIQNTIG
Sbjct: 361  LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQAILGSPASGIQNTIG 420

Query: 421  SVGTGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQM 480
            SVGTGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQM
Sbjct: 421  SVGTGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQM 480

Query: 481  RTLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIP 540
            RTLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIP
Sbjct: 481  RTLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIP 540

Query: 541  TAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEG 600
            TAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEG
Sbjct: 541  TAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEG 600

Query: 601  DMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQA 660
            DMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQA
Sbjct: 601  DMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQA 660

Query: 661  QPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGS 720
            QPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGS
Sbjct: 661  QPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGS 720

Query: 721  VPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTG 780
            VPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTG
Sbjct: 721  VPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTG 780

Query: 781  VSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMT 840
            VSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMT
Sbjct: 781  VSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMT 840

Query: 841  PPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPS 900
            PPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPS
Sbjct: 841  PPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPS 900

Query: 901  VATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMK 960
            VATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMK
Sbjct: 901  VATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMK 960

Query: 961  TETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVE 1020
            TETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVE
Sbjct: 961  TETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVE 1020

Query: 1021 VKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQ 1080
            VKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQ
Sbjct: 1021 VKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQ 1080

Query: 1081 LLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFC 1140
            LLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFC
Sbjct: 1081 LLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFC 1140

Query: 1141 SKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCE 1200
            SKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCE
Sbjct: 1141 SKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCE 1200

Query: 1201 KCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHY 1260
            KCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHY
Sbjct: 1201 KCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHY 1260

Query: 1261 DIIWPSGFVCDNCLKKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVF 1320
            DIIWPSGFVCDNCLKKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVF
Sbjct: 1261 DIIWPSGFVCDNCLKKTGRPRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVF 1320

Query: 1321 VRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYG 1380
            VRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYG
Sbjct: 1321 VRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYG 1380

Query: 1381 SDCPPPNTRRVYISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSE 1440
            SDCPPPNTRRVYISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSE
Sbjct: 1381 SDCPPPNTRRVYISYLDSIHFFRPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSE 1440

Query: 1441 GDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELP 1500
            GDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELP
Sbjct: 1441 GDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELP 1500

Query: 1501 YFEGDFWPNVLEESIKELEQEEEERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKS 1560
            YFEGDFWPNVLEESIKELEQEEEERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKS
Sbjct: 1501 YFEGDFWPNVLEESIKELEQEEEERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKS 1560

Query: 1561 SISRANKKKPSMPNVSNDLSQKLYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSC 1620
            SISRANKKKPSMPNVSNDLSQKLYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSC
Sbjct: 1561 SISRANKKKPSMPNVSNDLSQKLYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSC 1620

Query: 1621 DLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRW 1680
            DLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRW
Sbjct: 1621 DLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRW 1680

Query: 1681 HCTVCEDYDLCINCYNTKSHAHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQS 1740
            HCTVCEDYDLCINCYNTKSHAHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQS
Sbjct: 1681 HCTVCEDYDLCINCYNTKSHAHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQS 1740

Query: 1741 LVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKC 1800
            LVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKC
Sbjct: 1741 LVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKC 1800

Query: 1801 PVPFCLNIKHKLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPS 1860
            PVPFCLNIKHKLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPS
Sbjct: 1801 PVPFCLNIKHKLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPS 1860

Query: 1861 TPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEA 1920
            TPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEA
Sbjct: 1861 TPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEA 1920

Query: 1921 ARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPP 1980
            ARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPP
Sbjct: 1921 ARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPP 1980

Query: 1981 GQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPS 2040
            GQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPS
Sbjct: 1981 GQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPS 2040

Query: 2041 SPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPS 2100
            SPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPS
Sbjct: 2041 SPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPS 2100

Query: 2101 LQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLL 2160
            LQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLL
Sbjct: 2101 LQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLL 2160

Query: 2161 QQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQG 2220
            QQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQG
Sbjct: 2161 QQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQG 2220

Query: 2221 SSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQ 2280
            SSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQ
Sbjct: 2221 SSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQ 2280

Query: 2281 HMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSP 2340
            HMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSP
Sbjct: 2281 HMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSP 2340

Query: 2341 QTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKF 2400
            QTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKF
Sbjct: 2341 QTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKF 2400

Query: 2401 VEGL 2404
            VEGL
Sbjct: 2401 VEGL 2404


>gi|119943104 CREB binding protein isoform a [Homo sapiens]
          Length = 2442

 Score = 4900 bits (12711), Expect = 0.0
 Identities = 2403/2442 (98%), Positives = 2403/2442 (98%), Gaps = 38/2442 (1%)

Query: 1    MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV 60
            MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV
Sbjct: 1    MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLLNSGNLV 60

Query: 61   PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK 120
            PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK
Sbjct: 61   PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGK 120

Query: 121  SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN 180
            SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN
Sbjct: 121  SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNAN 180

Query: 181  FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA 240
            FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA
Sbjct: 181  FNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLA 240

Query: 241  ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK 300
            ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK
Sbjct: 241  ETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASK 300

Query: 301  QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL 360
            QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL
Sbjct: 301  QSMVNSLPTFPTDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVL 360

Query: 361  LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQA-------------- 406
            LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQ               
Sbjct: 361  LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK 420

Query: 407  ------------------------ILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS 442
                                    ILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS
Sbjct: 421  NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSS 480

Query: 443  MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ 502
            MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ
Sbjct: 481  MQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQ 540

Query: 503  QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL 562
            QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL
Sbjct: 541  QPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDL 600

Query: 563  RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK 622
            RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK
Sbjct: 601  RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK 660

Query: 623  IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG 682
            IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG
Sbjct: 661  IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG 720

Query: 683  MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT 742
            MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT
Sbjct: 721  MNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHT 780

Query: 743  NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA 802
            NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA
Sbjct: 781  NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA 840

Query: 803  SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT 862
            SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT
Sbjct: 841  SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPT 900

Query: 863  PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP 922
            PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP
Sbjct: 901  PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP 960

Query: 923  LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE 982
            LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE
Sbjct: 961  LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE 1020

Query: 983  MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP 1042
            MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP
Sbjct: 1021 MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP 1080

Query: 1043 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR 1102
            RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR
Sbjct: 1081 RKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKR 1140

Query: 1103 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC 1162
            KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC
Sbjct: 1141 KLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCC 1200

Query: 1163 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT 1222
            GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT
Sbjct: 1201 GRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQT 1260

Query: 1223 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK 1282
            TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK
Sbjct: 1261 TISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRK 1320

Query: 1283 ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFV 1342
            ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFV
Sbjct: 1321 ENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFV 1380

Query: 1343 DSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFF 1402
            DSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFF
Sbjct: 1381 DSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFF 1440

Query: 1403 RPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ 1462
            RPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ
Sbjct: 1441 RPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQ 1500

Query: 1463 EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE 1522
            EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE
Sbjct: 1501 EWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEE 1560

Query: 1523 EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK 1582
            EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK
Sbjct: 1561 EERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQK 1620

Query: 1583 LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS 1642
            LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS
Sbjct: 1621 LYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSS 1680

Query: 1643 LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH 1702
            LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH
Sbjct: 1681 LRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAH 1740

Query: 1703 KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR 1762
            KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR
Sbjct: 1741 KMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKR 1800

Query: 1763 VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ 1822
            VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ
Sbjct: 1801 VVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQ 1860

Query: 1823 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG 1882
            QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG
Sbjct: 1861 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAG 1920

Query: 1883 FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS 1942
            FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS
Sbjct: 1921 FPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNS 1980

Query: 1943 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI 2002
            MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI
Sbjct: 1981 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVI 2040

Query: 2003 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF 2062
            SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF
Sbjct: 2041 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF 2100

Query: 2063 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA 2122
            IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA
Sbjct: 2101 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQA 2160

Query: 2123 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG 2182
            MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG
Sbjct: 2161 MGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG 2220

Query: 2183 MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG 2242
            MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG
Sbjct: 2221 MAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLG 2280

Query: 2243 ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS 2302
            ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS
Sbjct: 2281 ADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLS 2340

Query: 2303 NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL 2362
            NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL
Sbjct: 2341 NQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHL 2400

Query: 2363 GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL 2404
            GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL
Sbjct: 2401 GNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVEGL 2442


>gi|50345997 E1A binding protein p300 [Homo sapiens]
          Length = 2414

 Score = 2697 bits (6990), Expect = 0.0
 Identities = 1486/2505 (59%), Positives = 1731/2505 (69%), Gaps = 260/2505 (10%)

Query: 1    MAENLLD-GPPNPKRAKLSSPGFSAN--DSTDFGSLFDLENDLPDELIPNGGELGLLNSG 57
            MAEN+++ GPP+ KR KLSSP  SA+  D TDFGSLFDLE+DLPDELI N  ELGL N G
Sbjct: 1    MAENVVEPGPPSAKRPKLSSPALSASASDGTDFGSLFDLEHDLPDELI-NSTELGLTNGG 59

Query: 58   NL---------VPDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPN 108
            ++         V DAASKHKQLSELLR GS  ++N G+G          G    +Q Q +
Sbjct: 60   DINQLQTSLGMVQDAASKHKQLSELLRSGSSPNLNMGVGG--------PGQVMASQAQQS 111

Query: 109  SANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQVGLATSSPAT 168
            S  +  +++M KSP++Q   ++P++      TSGP    +Q+         G+  S    
Sbjct: 112  SPGLGLINSMVKSPMTQAGLTSPNM---GMGTSGPNQGPTQS--------TGMMNSPVNQ 160

Query: 169  SQTGPGICMNANFNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGRGRGAGMPYPT 228
               G    MNA  N   PG+L + +G  ++        QVMNGS+GA GRGR   M YP 
Sbjct: 161  PAMGMNTGMNAGMN---PGMLAAGNGQGIMPN------QVMNGSIGA-GRGR-QNMQYPN 209

Query: 229  PAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPM 288
            P M G++ ++L E L Q SPQM G  GL   Q     KMG+  N +P+G P++Q  GQ +
Sbjct: 210  PGM-GSAGNLLTEPLQQGSPQMGGQTGLRGPQP---LKMGMMNNPNPYGSPYTQNPGQQI 265

Query: 289  GATGVNPQLASKQSMVNSLPTFPTDIKNTSVTNVPNMSQMQT----SVGIVPTQAIATGP 344
            GA+G+  Q+ +K  + N+L  F  D K      +PNM Q         G+V   A   G 
Sbjct: 266  GASGLGLQIQTKTVLSNNLSPFAMDKKAVPGGGMPNMGQQPAPQVQQPGLVTPVAQGMGS 325

Query: 345  ---TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAG 401
               TADPEKRKLIQQQLVLLLHAHKCQRREQANGEVR C+LPHCRTMKNVLNHMTHCQ+G
Sbjct: 326  GAHTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRQCNLPHCRTMKNVLNHMTHCQSG 385

Query: 402  KACQA---------------------------------------ILGSPASGIQNTIGSV 422
            K+CQ                                        + G+P  G+ N   S+
Sbjct: 386  KSCQVAHCASSRQIISHWKNCTRHDCPVCLPLKNAGDKRNQQPILTGAPV-GLGNP-SSL 443

Query: 423  GTGQQNATSLSNPNPIDPSSMQRAYAALGLPY-MNQPQTQLQPQVPGQQPAQP-QTHQQM 480
            G GQQ+A +LS  + IDPSS++RAYAALGLPY +NQ  TQ Q Q   QQ  QP Q+ Q M
Sbjct: 444  GVGQQSAPNLSTVSQIDPSSIERAYAALGLPYQVNQMPTQPQVQAKNQQNQQPGQSPQGM 503

Query: 481  RTLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIP 540
            R ++ +  +PM +  G      Q P+L+S+S L +++ + NP+M   S + ++ +L  +P
Sbjct: 504  RPMSNMSASPMGVNGG---VGVQTPSLLSDSMLHSAINSQNPMM---SENASVPSLGPMP 557

Query: 541  TAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEG 600
            TAA PS+TG+RK WHE +TQDLR+HLVHKLVQAIFPTPDPAALKDRRMENLVAYA+KVEG
Sbjct: 558  TAAQPSTTGIRKQWHEDITQDLRNHLVHKLVQAIFPTPDPAALKDRRMENLVAYARKVEG 617

Query: 601  DMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQP-PVIPQ 659
            DMYESAN+R EYYHLLAEKIYKIQKELEEKRR+RL KQ +L N   +      P P + Q
Sbjct: 618  DMYESANNRAEYYHLLAEKIYKIQKELEEKRRTRLQKQNMLPNAAGMVPVSMNPGPNMGQ 677

Query: 660  AQPVRPPNGPLSLP-----------VNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASP 708
             QP    NGPL  P           + R+    G+N F  MS+      Q P+ PR   P
Sbjct: 678  PQPGMTSNGPLPDPSMIRGSVPNQMMPRITPQSGLNQFGQMSMA-----QPPIVPRQTPP 732

Query: 709  MNHSVQMNSMGSV-PGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSS-G 766
            + H  Q+   G++ P M   P RM QP N               Q QFLPQ QFPS    
Sbjct: 733  LQHHGQLAQPGALNPPMGYGP-RMQQPSN---------------QGQFLPQTQFPSQGMN 776

Query: 767  AMSVGMGQPPAQTGVSQGQVPGAALP--NPLNMLGPQASQLPCPPVTQSPLH---PTPPP 821
              ++ +     Q  VSQ Q+  ++ P  +P+   G Q S + CP + Q  LH   P+P P
Sbjct: 777  VTNIPLAPSSGQAPVSQAQMSSSSCPVNSPIMPPGSQGSHIHCPQLPQPALHQNSPSPVP 836

Query: 822  ASTAAGM---PSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTP 878
            + T       PS+    PP  T P P  PT P+ P     Q   P P   P+   TQ   
Sbjct: 837  SRTPTPHHTPPSIGAQQPPATTIPAPV-PTPPAMPPGPQSQALHPPPRQTPTPPTTQLPQ 895

Query: 879  TVQAAAQAQVTP-QPQTPVQPPSVATPQSSQQQPT-PVHAQPPGTPLSQAAASIDNRVPT 936
             VQ +  A  +  QPQ   QP S  +  +S   PT P+    P TPLSQ A SI+ +V  
Sbjct: 896  QVQPSLPAAPSADQPQQ--QPRSQQSTAASVPTPTAPLLPPQPATPLSQPAVSIEGQVSN 953

Query: 937  PSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKE 996
            P S +S E NSQ      P  E+K E + E  +P+P +++ E  SE   ED         
Sbjct: 954  PPSTSSTEVNSQAIAEKQPSQEVKMEAKMEVDQPEPADTQPEDISESKVEDC-------- 1005

Query: 997  ETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQAL 1056
                   K E  E +E+  E+K E+KEEE+  S      S +P Q +KKIFKPEELRQAL
Sbjct: 1006 -------KMESTETEERSTELKTEIKEEEDQPSTSATQSSPAPGQSKKKIFKPEELRQAL 1058

Query: 1057 MPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYV 1116
            MPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVK+PMDLSTIKRKLDTGQYQEPWQYV
Sbjct: 1059 MPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKSPMDLSTIKRKLDTGQYQEPWQYV 1118

Query: 1117 DDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYCCGRKYEFSPQTLCCY 1176
            DD+WLMFNNAWLYNRKTSRVYK+CSKL+EVFEQEIDPVMQSLGYCCGRK EFSPQTLCCY
Sbjct: 1119 DDIWLMFNNAWLYNRKTSRVYKYCSKLSEVFEQEIDPVMQSLGYCCGRKLEFSPQTLCCY 1178

Query: 1177 GKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQTTISKDQFEKKKNDT 1236
            GKQLCTIPRDA YYSYQNRYHFCEKCF EIQGE+V+LGDDPSQPQTTI+K+QF K+KNDT
Sbjct: 1179 GKQLCTIPRDATYYSYQNRYHFCEKCFNEIQGESVSLGDDPSQPQTTINKEQFSKRKNDT 1238

Query: 1237 LDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPRKENKFSAKRLQTTRL 1296
            LDPE FV+C ECGRKMHQICVLH++IIWP+GFVCD CLKK+ R RKENKFSAKRL +TRL
Sbjct: 1239 LDPELFVECTECGRKMHQICVLHHEIIWPAGFVCDGCLKKSARTRKENKFSAKRLPSTRL 1298

Query: 1297 GNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRFVDSGEMSESFPYRTK 1356
            G  LE+RVN FLRRQNHPE+GEV VRVV +SDKTVEVKPGMK+RFVDSGEM+ESFPYRTK
Sbjct: 1299 GTFLENRVNDFLRRQNHPESGEVTVRVVHASDKTVEVKPGMKARFVDSGEMAESFPYRTK 1358

Query: 1357 ALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHFFRPRCLRTAVYHEIL 1416
            ALFAFEEIDGVD+CFFGMHVQEYGSDCPPPN RRVYISYLDS+HFFRP+CLRTAVYHEIL
Sbjct: 1359 ALFAFEEIDGVDLCFFGMHVQEYGSDCPPPNQRRVYISYLDSVHFFRPKCLRTAVYHEIL 1418

Query: 1417 IGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAFAER 1476
            IGYLEYVKKLGY TGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKA +ER
Sbjct: 1419 IGYLEYVKKLGYTTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRLQEWYKKMLDKAVSER 1478

Query: 1477 IIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKKEESTAASET 1536
            I+HDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERK+EE+T ++E+
Sbjct: 1479 IVHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELEQEEEERKREENT-SNES 1537

Query: 1537 TEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQKLYATMEKHKEVFFV 1596
            T+ ++GDSKNAKKKNNKKT+KNKSS+SR NKKKP MPNVSNDLSQKLYATMEKHKEVFFV
Sbjct: 1538 TDVTKGDSKNAKKKNNKKTSKNKSSLSRGNKKKPGMPNVSNDLSQKLYATMEKHKEVFFV 1597

Query: 1597 IHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFSSLRRSKWSTLCMLVE 1656
            I L AGP  N+LPPIVDPDPL+ CDLMDGRDAFLTLARDKH EFSSLRR++WST+CMLVE
Sbjct: 1598 IRLIAGPAANSLPPIVDPDPLIPCDLMDGRDAFLTLARDKHLEFSSLRRAQWSTMCMLVE 1657

Query: 1657 LHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHAHKMVKWGLGLDDEGS 1716
            LHTQ QDRFVYTCNECKHHVETRWHCTVCEDYDLCI CYNTK+H HKM K GLGLDDE +
Sbjct: 1658 LHTQSQDRFVYTCNECKHHVETRWHCTVCEDYDLCITCYNTKNHDHKMEKLGLGLDDESN 1717

Query: 1717 SQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNG 1776
            +Q    ++SP +SRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNG
Sbjct: 1718 NQQAAATQSPGDSRRLSIQRCIQSLVHACQCRNANCSLPSCQKMKRVVQHTKGCKRKTNG 1777

Query: 1777 GCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQQAQLMRRRMATMNT 1836
            GCP+CKQLIALCCYHAKHCQENKCPVPFCLNIK KLRQQQ+QHRLQQAQ++RRRMA+M  
Sbjct: 1778 GCPICKQLIALCCYHAKHCQENKCPVPFCLNIKQKLRQQQLQHRLQQAQMLRRRMASMQR 1837

Query: 1837 RNV--PQQSLPSPTSAPPGTPT-QQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPT 1893
              V   QQ LPSPT A P TPT QQP+TPQTPQP +QPQP+P +  P   P + RTQ   
Sbjct: 1838 TGVVGQQQGLPSPTPATPTTPTGQQPTTPQTPQPTSQPQPTPPNSMP---PYLPRTQAAG 1894

Query: 1894 TVSTGKPTSQV--PAPPPPAQ-----PPPAAVEAARQIEREAQQQQHLYRVN-----INN 1941
             VS GK   QV  P PP  AQ     PPPAAVE A QI+R A+ Q+ +  V      I +
Sbjct: 1895 PVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMAMQIQRAAETQRQMAHVQIFQRPIQH 1954

Query: 1942 SMPPGRTGMGTPGSQMAPVSLNVPRPNQ-VSGPVMPSMPP------GQWQQAPLPQ-QQP 1993
             MPP      TP   MAP+ +N P   +  SG + P M P        W Q  LPQ QQ 
Sbjct: 1955 QMPP-----MTP---MAPMGMNPPPMTRGPSGHLEPGMGPTGMQQQPPWSQGGLPQPQQL 2006

Query: 1994 MPGLPRPVISMQAQ-------AAVAGPRMPSVQP--PRSISPSALQDLLRTLKSPSSPQQ 2044
              G+PRP +   AQ       A   G     + P  P ++S  ALQ+LLRTL+SPSSP Q
Sbjct: 2007 QSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKPGTVSQQALQNLLRTLRSPSSPLQ 2066

Query: 2045 QQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQP-QPGL-QSQPGMQP-----QPGMHQ 2097
            QQQVL+IL +NPQL+AAFIKQR AKY  + P   P QPG+ Q QPG+QP     Q G+H 
Sbjct: 2067 QQQVLSILHANPQLLAAFIKQRAAKYANSNPQPIPGQPGMPQGQPGLQPPTMPGQQGVHS 2126

Query: 2098 QPSLQNLNAMQAGVPRPGVP---PQQQ---AMGGLNPQGQALNIMNPGHNPNMASMNPQY 2151
             P++QN+N MQAGV R G+P   PQQQ    MGG++PQ Q    MN  HN    +M  Q+
Sbjct: 2127 NPAMQNMNPMQAGVQRAGLPQQQPQQQLQPPMGGMSPQAQQ---MNMNHN----TMPSQF 2179

Query: 2152 REMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQR 2211
            R++LRR          QQ  QQQQQQ    G+  GMA H QFQQPQG  GYPP  QQQQR
Sbjct: 2180 RDILRR----------QQMMQQQQQQGAGPGIGPGMANHNQFQQPQGV-GYPP--QQQQR 2226

Query: 2212 MQQHLPLQGSSMGQMAAQMGQLGQMGQ--PGLGADSTPNIQQALQQRILQQQQMKQQIGS 2269
            MQ H       M QM  Q G +GQ+GQ    LGA++  ++ QA QQR+LQ     QQ+GS
Sbjct: 2227 MQHH-------MQQM--QQGNMGQIGQLPQALGAEAGASL-QAYQQRLLQ-----QQMGS 2271

Query: 2270 PGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRI 2329
            P QPNPMSPQQHML  Q Q+ HL GQQI  SLSNQVRSP PV SPRPQSQPPHSSPSPR+
Sbjct: 2272 PVQPNPMSPQQHMLPNQAQSPHLQGQQIPNSLSNQVRSPQPVPSPRPQSQPPHSSPSPRM 2331

Query: 2330 QPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQL 2374
            QPQPSPHHVSPQT SPHPGL    A+ ++QGH  +P+Q++ML QL
Sbjct: 2332 QPQPSPHHVSPQTSSPHPGLVAAQANPMEQGHFASPDQNSMLSQL 2376



 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 66/283 (23%), Positives = 99/283 (34%), Gaps = 43/283 (15%)

Query: 2157 RQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQF--------------QQPQGPGGY 2202
            +Q L+QQQ Q + QQ Q  +++ ++    G+ G  Q               QQP  P   
Sbjct: 1810 KQKLRQQQLQHRLQQAQMLRRRMASMQRTGVVGQQQGLPSPTPATPTTPTGQQPTTPQTP 1869

Query: 2203 PPAMQQQ----QRMQQHLPL--------QGSSMGQMAA----QMGQLGQMGQPGLGADST 2246
             P  Q Q      M  +LP         QG + GQ+      Q  Q    G P    +  
Sbjct: 1870 QPTSQPQPTPPNSMPPYLPRTQAAGPVSQGKAAGQVTPPTPPQTAQPPLPGPPPAAVEMA 1929

Query: 2247 PNIQQALQ-QRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQV 2305
              IQ+A + QR +   Q+ Q+      P PM+P   M    P  +  P   +   +    
Sbjct: 1930 MQIQRAAETQRQMAHVQIFQRPIQHQMP-PMTPMAPMGMNPPPMTRGPSGHLEPGMG--- 1985

Query: 2306 RSPAPVQSPRPQSQPPHSSPSPRIQPQPSP------HHVSPQTGSPHPGLAVTMASSIDQ 2359
              P  +Q   P SQ     P       P P       H  P   +P PGL     S +  
Sbjct: 1986 --PTGMQQQPPWSQGGLPQPQQLQSGMPRPAMMSVAQHGQPLNMAPQPGLGQVGISPLKP 2043

Query: 2360 GHLGNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVE 2402
            G +       +L  L +PS      ++  +       L  F++
Sbjct: 2044 GTVSQQALQNLLRTLRSPSSPLQQQQVLSILHANPQLLAAFIK 2086


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score =  102 bits (253), Expect = 6e-21
 Identities = 123/463 (26%), Positives = 175/463 (37%), Gaps = 74/463 (15%)

Query: 1922 RQIEREAQQQQHLYRVNINNSMPPG---------------RTGMGTPGSQMAPVSLNVPR 1966
            +Q +++ QQQQH   + ++ S  P                +   G PG Q   + L    
Sbjct: 3602 QQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTP-- 3659

Query: 1967 PNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPR---MPSVQPPRS 2023
                 G  +P  P G +    L QQQ                ++AGP     P     RS
Sbjct: 3660 ----GGMALPGQPGGPFLNTALAQQQQQQ-------HSGGAGSLAGPSGGFFPGNLALRS 3708

Query: 2024 ISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGL 2083
            + P +     R L+      QQQ++    K   Q      +Q     VA Q   Q  PG+
Sbjct: 3709 LGPDS-----RLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGV 3763

Query: 2084 QSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQ------------QQAMGGLNPQGQ 2131
            Q+   + P+P     PS      +Q   P+P   PQ            QQ  G L PQG 
Sbjct: 3764 QTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGP 3823

Query: 2132 ALNI-MNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGH 2190
               + M      +   +  Q + ++  +L+  QQQQQQQQ QQQ    G + +   +  H
Sbjct: 3824 HRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSH 3883

Query: 2191 -GQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNI 2249
             GQ +    P G    +QQQQ++QQ   LQ         Q  QL Q              
Sbjct: 3884 SGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQ-------QQQQLQQ-------------- 3922

Query: 2250 QQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPA 2309
            QQ LQQ+ LQQQQ +QQ+    Q      QQ +   Q Q      QQ        +    
Sbjct: 3923 QQQLQQQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSR 3982

Query: 2310 PVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVT 2352
             + SP+ Q Q    +  P +  +P  H  SP  G+  P L +T
Sbjct: 3983 TLLSPQ-QQQQQQVALGPGMPAKPLQHFSSP--GALGPTLLLT 4022



 Score = 86.3 bits (212), Expect = 3e-16
 Identities = 142/558 (25%), Positives = 214/558 (38%), Gaps = 96/558 (17%)

Query: 1809 KHKLRQQQIQHRLQ-QAQLMRRRMATMNTRNV---PQQSLPSPTSAPPGTPT---QQPST 1861
            + +L+QQQ Q + Q Q Q  +++M  +N       PQQ      +  PG P    Q  S+
Sbjct: 3952 QQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSS 4011

Query: 1862 P-----------------------QTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTG 1898
            P                       +  + P+  Q  P+++     P    T+P     + 
Sbjct: 4012 PGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTT--PESMATEPGEVKPSL 4069

Query: 1899 KPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMA 1958
               SQ+    P  QP P++++    +    QQQQ +  ++       G+ G G+  S+ +
Sbjct: 4070 SGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGS-SSEAS 4128

Query: 1959 PVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQA-QAAVAGPRMPS 2017
             V   + +P+   G       PG   Q  L  QQPM  L RP+ +    Q    GP + S
Sbjct: 4129 SVPHLLAQPSVSLGD-----QPGSMTQNLLGPQQPM--LERPMQNNTGPQPPKPGPVLQS 4181

Query: 2018 VQ--PPRSISPSA------LQDLLRTLKSPS----SPQQQQQVLNILKSNPQLMAAFIKQ 2065
             Q  P   I P+       LQ +L   K+P     SPQQQQQ L  L    QL  +   +
Sbjct: 4182 GQGLPGVGIMPTVGQLRAQLQGVL--AKNPQLRHLSPQQQQQ-LQALLMQRQLQQSQAVR 4238

Query: 2066 RTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGG 2125
            +T  Y   +PG Q  P LQ   G QPQ G    P    L  + AG PRP  PP+  A  G
Sbjct: 4239 QTPPY--QEPGTQTSP-LQGLLGCQPQLGGFPGPQTGPLQELGAG-PRPQGPPRLPAPPG 4294

Query: 2126 LNPQGQALNIMNP------GHNPNMASMNPQYREML--RRQLLQQQQQQQQQQQQQQQQQ 2177
                G  L  ++P         P   S  P     L    QL        + Q    +  
Sbjct: 4295 ALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPP 4354

Query: 2178 QGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQG---SSMGQMAAQMGQLG 2234
             G    A        F +  GP   P  + + Q+ +Q   + G      GQ+  +  QL 
Sbjct: 4355 PGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLS 4414

Query: 2235 QMGQP-----GLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQP-- 2287
               +P      LGA S            ++++   + IG+PG  N      H+L   P  
Sbjct: 4415 IKQEPREEPCALGAQS------------VKREANGEPIGAPGTSN------HLLLAGPRS 4456

Query: 2288 QASHLPGQQIATSLSNQV 2305
            +A HL  Q++  + + Q+
Sbjct: 4457 EAGHLLLQKLLRAKNVQL 4474



 Score = 82.0 bits (201), Expect = 6e-15
 Identities = 153/614 (24%), Positives = 215/614 (35%), Gaps = 105/614 (17%)

Query: 1809 KHKLRQQQIQHRLQQAQLMRRRMATMNTR---NVPQQSLPS----PTSAPPG-------- 1853
            K + +QQQ Q + QQ   +     + + R    +P Q LP     P   PPG        
Sbjct: 3598 KQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRL 3657

Query: 1854 TP-----TQQPSTPQTPQPPAQPQPSPVS------MSPAG--FPS--VARTQPPTTVSTG 1898
            TP       QP  P      AQ Q    S        P+G  FP     R+  P +    
Sbjct: 3658 TPGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQ 3717

Query: 1899 KPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLY-RVNINNSMPPGRTGMGTPGSQM 1957
            +   Q+       Q      +  +Q +++ QQQQHL  +V I      G      PG Q 
Sbjct: 3718 ERQLQLQ------QQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQG------PGVQT 3765

Query: 1958 APVSLNVPRPNQVSGPVMPS-MPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMP 2016
                      NQ  GP     MPP   Q   + Q  P P      +   AQ AV   + P
Sbjct: 3766 ----------NQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHP 3815

Query: 2017 SVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPG 2076
                P+      L    R L SP   QQ Q ++       Q      +Q+  +   +  G
Sbjct: 3816 GALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQ---QQQQHQQQGSMAG 3872

Query: 2077 MQP-QPGLQSQPGMQPQPGMHQQP--SLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQAL 2133
            +   Q  L S  G   QP +  QP  SLQ L   Q    +  +  QQQ       Q Q  
Sbjct: 3873 LSHLQQSLMSHSG---QPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQ 3929

Query: 2134 NIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQ-QQQQQQQQQGSAGMAGGMAGHGQ 2192
             +        +     Q  +  ++QL QQQQQQQQQ QQQQQQQQ G    +  +    Q
Sbjct: 3930 QLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQ 3989

Query: 2193 FQQPQ----------------GPGGYPPAMQQQQRMQ------------------QHLPL 2218
             QQ Q                 PG   P +    + Q                  Q  PL
Sbjct: 3990 QQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPL 4049

Query: 2219 Q-GSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMS 2277
              G++   MA + G++    +P L  DS   + Q   Q      Q++  +  PGQ     
Sbjct: 4050 AIGTTPESMATEPGEV----KPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQV 4105

Query: 2278 PQQHMLSGQPQASHLPGQQI-ATSLSNQVRSPAPVQSPRPQSQPPH-SSPSPRIQPQPSP 2335
               H   G        G    A+S+ + +  P+     +P S   +   P   +  +P  
Sbjct: 4106 SLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQ 4165

Query: 2336 HHVSPQTGSPHPGL 2349
            ++  PQ   P P L
Sbjct: 4166 NNTGPQPPKPGPVL 4179



 Score = 69.3 bits (168), Expect = 4e-11
 Identities = 152/642 (23%), Positives = 231/642 (35%), Gaps = 121/642 (18%)

Query: 1809 KHKLRQQQIQHRLQQAQLMRRRMATMNTRNVP----QQSLPSPTSAPPGTPTQQPST--- 1861
            K   ++QQ+  +LQ AQ  +++    +  + P      SLP   S+P    +QQ  +   
Sbjct: 3258 KELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGL 3317

Query: 1862 -----PQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPA 1916
                 P  PQP    QP   ++     PS+A       + +G+   Q    P  +  P  
Sbjct: 3318 AGARQPGLPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVL 3377

Query: 1917 AVEAARQIEREA--QQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPV 1974
            + +    +      + QQ   +  + NS  P  T +    ++     +   +   + G +
Sbjct: 3378 SQKPMGTMPPSMCMKPQQLAMQQQLANSFFPD-TDLDKFAAEDIIDPIAKAKMVALKG-I 3435

Query: 1975 MPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLR 2034
               M  G    AP        G+ R  +S+ AQ    GP   S      ++  + Q+  R
Sbjct: 3436 KKVMAQGSIGVAP--------GMNRQQVSLLAQRLSGGP---SSDLQNHVAAGSGQE--R 3482

Query: 2035 TLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQ-PGMQPQP 2093
            +   PS P          + NP   A  +     +    +     Q  LQ Q   ++ Q 
Sbjct: 3483 SAGDPSQP----------RPNPPTFAQGVINEADQRQYEEWLFHTQQLLQMQLKVLEEQI 3532

Query: 2094 GMHQQPSLQNLNAMQAGVPRPGVP-PQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYR 2152
            G+H++ S + L A Q    + G   P+  A        Q   I        +  +  Q +
Sbjct: 3533 GVHRK-SRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQK-----QLDQVRKQQK 3586

Query: 2153 EMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGG---------------MAGHGQFQQPQ 2197
            E        + +QQQQQQQQQQQQQQ SA +A                 + GHG  Q PQ
Sbjct: 3587 EHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHG-LQPPQ 3645

Query: 2198 G-PGGYPPAMQ---------------------QQQRMQQHLPLQGSSMGQMAAQMGQL-- 2233
            G PGG    ++                      QQ+ QQH        G +A   G    
Sbjct: 3646 GPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQH----SGGAGSLAGPSGGFFP 3701

Query: 2234 GQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGS--PGQPNPMSPQQHMLSG---QPQ 2288
            G +    LG DS     + LQ+R LQ QQ + Q+      Q      QQH+L     Q Q
Sbjct: 3702 GNLALRSLGPDS-----RLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQ 3756

Query: 2289 ASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPG 2348
                PG Q   +L            P+PQ   P SS    +  Q SP    PQ   P   
Sbjct: 3757 QQQGPGVQTNQAL-----------GPKPQGLMPPSSHQGLLVQQLSPQ--PPQ--GPQGM 3801

Query: 2349 LAVTMASSIDQGHLG-----NPEQSAMLPQLNTPSRSALSSE 2385
            L     + + Q H G      P +  ++ Q    S   L+ +
Sbjct: 3802 LGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQ 3843



 Score = 68.6 bits (166), Expect = 7e-11
 Identities = 108/496 (21%), Positives = 172/496 (34%), Gaps = 66/496 (13%)

Query: 634  RLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQG------MNSFN 687
            R HK    G Q          PV  +  P  P + P   P       QG      + S  
Sbjct: 348  RCHKAQ--GGQTIRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQ 405

Query: 688  PMSLGNVQLPQAPMG-------PRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGA 740
            P   G +Q    P+G       P+  +P+N  + +        ++  P   P  P    +
Sbjct: 406  PKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEAS 465

Query: 741  HTNNMMAQAPAQSQ------FLPQNQFPSSSGAMSVGMGQPPAQTGVS----------QG 784
              +    + PA           P  + P S       +  PP  +  S          + 
Sbjct: 466  RLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEE 525

Query: 785  QVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQP 844
              P  AL  PL+   P+AS L  PP  +SPL P P    T+    + + + PP  +P  P
Sbjct: 526  SPPSPALETPLSP-PPEASPLS-PPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSP 583

Query: 845  AAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQ-TPVQPPSVAT 903
                 P +P   + +   P   S P +   + +P       ++++P P+ +P+ PP   +
Sbjct: 584  PPEESPMSPPPEASRLFPPFEES-PLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEES 642

Query: 904  PQS-----SQQQPTPVHAQ----PPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDV 954
            P S     S+  P PV ++    P  +PLS          P P      E +   P P+ 
Sbjct: 643  PMSPPPEVSRLSPLPVVSRLSPPPEESPLS----------PPP------EESPTSPPPEA 686

Query: 955  PVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGAS--QVKEETDIAEQKSEPMEVDE 1012
              L    E       P+   +   P   +M   L+ +    + EE  +   +SE   +  
Sbjct: 687  SRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLC-PRSEGPHLSP 745

Query: 1013 KKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALY-RQDPESL 1071
            +  E  +  + EE   S        SP QP +           L P  E  +    PE L
Sbjct: 746  RPEEPHLSPRPEEPHLSPQAEEPHLSP-QPEEPCLCAVPEEPHLSPQAEGPHLSPQPEEL 804

Query: 1072 PFR-QPVDPQLLGIPD 1086
                Q  +P L  +P+
Sbjct: 805  HLSPQTEEPHLSPVPE 820



 Score = 65.1 bits (157), Expect = 8e-10
 Identities = 134/597 (22%), Positives = 221/597 (37%), Gaps = 98/597 (16%)

Query: 1840 PQQSLPSPTSAPPGTPTQQ--PSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVST 1897
            P++S PSP    P +P  +  P +P   + P  P P  +  SP   P  +R  PP     
Sbjct: 523  PEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPP--PEASRLSPP----- 575

Query: 1898 GKPTSQVPAPPP---PAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTP- 1953
              P     +PPP   P  PPP   EA+R      +            S PP  + +  P 
Sbjct: 576  --PEESPMSPPPEESPMSPPP---EASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPP 630

Query: 1954 -GSQMAPVSLNVPR--PNQVSG----PVMP--SMPPGQWQQAPLPQQQPMPGLPRPVISM 2004
              S M+P     P   P +VS     PV+   S PP +   +P P++ P    P      
Sbjct: 631  EDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPP------ 684

Query: 2005 QAQAAVAGPRMPSVQPPRSISPSA--LQDLLRTL---KSPSSPQQQQQVLNILKSNPQLM 2059
            +A      P      PP   SP++   +D L +L   +SP  P  ++  L      P L 
Sbjct: 685  EASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLS 744

Query: 2060 AAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQ---PGMHQQPSLQNLNAMQAGVPRPGV 2116
                          +P + P+P    +P + PQ   P +  QP    L A+      P +
Sbjct: 745  PR----------PEEPHLSPRP---EEPHLSPQAEEPHLSPQPEEPCLCAVP---EEPHL 788

Query: 2117 PPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQ 2176
             PQ +    L+PQ + L++      P+   ++P   E       ++     Q ++     
Sbjct: 789  SPQAEG-PHLSPQPEELHLSPQTEEPH---LSPVPEEPCLSPQPEESHLSPQSEEPCLSP 844

Query: 2177 QQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQM 2236
            +   + ++  +       +P+ P   P      + +    P    S+  +         +
Sbjct: 845  RPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPL---------L 895

Query: 2237 GQPGLGADSTPNIQQALQQRILQ---QQQMKQQIGSPGQ-PNPMSPQQHMLSGQPQASHL 2292
            G+P L     P +    ++  L    +  +  Q+  P   P P+SP     +  P  S L
Sbjct: 896  GEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSP-IITAAAPPALSPL 954

Query: 2293 PGQQIATSLSNQVRSPAPVQSP---RPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGL 2349
               +            +P+ +P    P S PP ++ +    P+P P  + P    P PG 
Sbjct: 955  GELEYPFGAKGDSDPESPLAAPILETPISPPPEANCT---DPEPVPPMILP----PSPGS 1007

Query: 2350 AVTMASSIDQGHLGNPE-----QSAMLPQLNTPSRS-------ALSSELSLVGDTTG 2394
             V  AS I    L  P+     Q +++PQ + PS+        ++ S LS +G   G
Sbjct: 1008 PVGPASPILMEPL-PPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVG 1063



 Score = 61.2 bits (147), Expect = 1e-08
 Identities = 130/567 (22%), Positives = 185/567 (32%), Gaps = 119/567 (20%)

Query: 1840 PQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPV----------SMSPAGFPS---- 1885
            P+   P P S PP  P  +       +PP +PQP  V          S+   GFP+    
Sbjct: 2442 PRFQSPDPYSRPPSRPQSRDPFAPLHKPP-RPQPPEVAFKAGSLAHTSLGAGGFPAALPA 2500

Query: 1886 ---------VARTQPPTTV---------------------STGKPTSQVPAPPPPAQPPP 1915
                     V   QPP  V                     + G+P+ + P P P   PP 
Sbjct: 2501 GPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPH 2560

Query: 1916 AAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVM 1975
                         + Q   Y V   N  P G     + GS      L+  RP  V   + 
Sbjct: 2561 GINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSV---LP 2617

Query: 1976 PSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRT 2035
            P  P G          Q   G+  PV   +      G  + + + P +  P  +  L +T
Sbjct: 2618 PPAPDGSLPYLSHGASQ-RSGITSPVEKREDPGTGMGSSLATAELPGTQDP-GMSGLSQT 2675

Query: 2036 LKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGM 2095
                   Q+Q+Q L  L    Q+    ++Q      A    + P     ++P        
Sbjct: 2676 ---ELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEP-------- 2724

Query: 2096 HQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMN------- 2148
               P+ + L+  Q   P  G    + ++ GL P   +  I+ PG  P+   ++       
Sbjct: 2725 -SSPAFEQLSRGQ--TPFAGT-QDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPAT 2780

Query: 2149 PQYREMLRRQLLQQQQ------------QQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQP 2196
            P   ++  RQL+   Q              QQQQQQ  QQQQ +A  +   A   +F   
Sbjct: 2781 PSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPST 2840

Query: 2197 QGPG-GYPPAMQQQQRMQQHLPLQGSSMGQMA--AQMGQLGQMGQPGLGADSTPNIQQAL 2253
             GP  G          +   LP  G  +   A  AQ  +L    Q GLG   TP      
Sbjct: 2841 PGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTP------ 2894

Query: 2254 QQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQS 2313
                            PGQ  P  P+ + +S  P      G      L     S  P Q 
Sbjct: 2895 ---------------FPGQGPPQRPRFYPVSEDPHRLAPEG------LRGLAVSGLPPQK 2933

Query: 2314 PRPQSQPPHSSPSPRIQPQPSPHHVSP 2340
            P   S PP  +P       P+PH   P
Sbjct: 2934 P---SAPP--APELNNSLHPTPHTKGP 2955



 Score = 58.5 bits (140), Expect = 8e-08
 Identities = 98/448 (21%), Positives = 162/448 (36%), Gaps = 87/448 (19%)

Query: 653  QPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQ-APMGPRAASPMNH 711
            +PP+ P+  P +PP  P   P                     +LP   P G  + SP+  
Sbjct: 857  KPPLSPR--PEKPPEEPGQCPAPE------------------ELPLFPPPGEPSLSPLLG 896

Query: 712  SVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVG 771
               ++  G  P ++  P  +P  P+           +     Q +P +  P     + + 
Sbjct: 897  EPALSEPGEPP-LSPLPEELPLSPS----------GEPSLSPQLMPPDPLPPPLSPI-IT 944

Query: 772  MGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLP-CPPVTQSPLHPTPPPASTAAGMPS 830
               PPA +       P   L  P    G    + P   P+ ++P+ P PP A+     P 
Sbjct: 945  AAAPPALS-------PLGELEYPFGAKGDSDPESPLAAPILETPISP-PPEANCTDPEP- 995

Query: 831  LQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPT-VQAAAQAQVT 889
                 PP + PP P +P  P++P+      P  +P    S     S P+     A     
Sbjct: 996  ----VPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSV 1051

Query: 890  PQPQTPV-QPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQ 948
            P P +P+ +   V+      +  T   ++P    L  +A S     P PS +      + 
Sbjct: 1052 PSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATS-----PLPSPMGDLSCPAP 1106

Query: 949  QPGPDVPVLEMKTE-------TQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIA 1001
             P P +       E         A  ++P+PG++ G   SE     L+G+  + +  ++A
Sbjct: 1107 SPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASE-----LKGSPVLLDPEELA 1161

Query: 1002 EQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKI--FKPEELRQALMPT 1059
                 PMEV    PE K          + G  S      +PR  +    P  ++  ++  
Sbjct: 1162 --PVTPMEV---YPECK---------QTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNE 1207

Query: 1060 LEALYRQDPE-SLPFRQPVDPQLLGIPD 1086
            +  L + D   S P  +P    LLG PD
Sbjct: 1208 ISNLSQGDASASFPGSEP----LLGSPD 1231



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 130/641 (20%), Positives = 202/641 (31%), Gaps = 103/641 (16%)

Query: 1806 LNIKHKLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTP 1865
            +N   K  + QI  + +   + R+         +P Q     +  P   PT    +P TP
Sbjct: 2073 INKVQKQAESQINKQTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTP 2132

Query: 1866 -----------QPPAQPQPSPVSMS------PAGFPSVARTQPPTTVSTGKPTS-QVPAP 1907
                       +PPA   P P S        P   P+   +Q P  ++   P   + P  
Sbjct: 2133 AGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTA 2192

Query: 1908 PPPAQPPPAAVEAARQIER-EAQQQQHLYRVNINNSMPPGRTGMGTPGSQMA-PVSLNVP 1965
            PP   P P+   A  Q     A  +    +    ++ PPG     TP  Q + P     P
Sbjct: 2193 PPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPG-----TPRHQPSTPDPFLKP 2247

Query: 1966 RPNQVSGPVMPSMPPGQWQQAPLPQQQPMP-GLPRPVISMQAQAAVAGPRMPSVQPPRSI 2024
            R   +    +P  P     +A  P   P P G  R  + ++ +    G   PS  PP   
Sbjct: 2248 RCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEEL--GASSPSYGPPN-- 2303

Query: 2025 SPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGM-----QP 2079
                       L    SP     +  +    P +  A +  R ++     PG+     +P
Sbjct: 2304 -----------LGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEP 2352

Query: 2080 QPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPP--------------------- 2118
             P     P     P + +  S  +  A     PRP  PP                     
Sbjct: 2353 PPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVP 2412

Query: 2119 -----QQQAMGGLNPQGQALNIMNPGH-NPNMASMNPQYREMLRRQLLQQQQQQQQQQQQ 2172
                 Q  +   L P+  +     P    P   S +P  R   R     Q +       +
Sbjct: 2413 ASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSR----PQSRDPFAPLHK 2468

Query: 2173 QQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQ 2232
              + Q        G   H       G GG+P A+      + H  +              
Sbjct: 2469 PPRPQPPEVAFKAGSLAHTSL----GAGGFPAALPAGPAGELHAKVPSGQPPNF------ 2518

Query: 2233 LGQMGQPGLGA-DSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHM----LSGQP 2287
               +  PG GA   TP+  +    + + +  +K  +  PG P P     H       G+P
Sbjct: 2519 ---VRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKP 2575

Query: 2288 QASHLPGQQIATSLSNQVRSP-APVQSPRPQSQPPHSSPSPRIQPQPSPHHVSP---QTG 2343
            Q+++     +AT   +   SP  P      +S        P + P P+P    P      
Sbjct: 2576 QSTN---YTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGA 2632

Query: 2344 SPHPGLAVTMASSIDQG-HLGNPEQSAMLPQLNTPSRSALS 2383
            S   G+   +    D G  +G+   +A LP    P  S LS
Sbjct: 2633 SQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLS 2673



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 81/305 (26%), Positives = 104/305 (34%), Gaps = 36/305 (11%)

Query: 650  PGAQPPVIPQAQPVRP-----------PNGPLS-LPVNRMQVSQGMNSFNPMSLGNVQLP 697
            P AQPP+ P+ QP  P           P+ P S +P +    S   +   P  L      
Sbjct: 2377 PYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFC 2436

Query: 698  QAPMGPRAASPMNHS-VQMNSMGSVPGMAISPSRMPQPPNMMG-----AHTNNMMAQAPA 751
             +P+ PR  SP  +S          P   +     PQPP +       AHT+      PA
Sbjct: 2437 PSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPA 2496

Query: 752  QSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPC--PP 809
                LP    P+      V  GQPP     S G       P+P+    PQA   P   PP
Sbjct: 2497 A---LPAG--PAGELHAKVPSGQPPNFVR-SPGTGAFVGTPSPMRFTFPQAVGEPSLKPP 2550

Query: 810  VTQSPLHPTP------PPASTAAGMPSLQHTTPPGMTPP--QPAAPTQPSTPVSSSGQTP 861
            V Q  L P         P  T     S  +T   G   P   P  P+  ST   S G +P
Sbjct: 2551 VPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTG-ESYGLSP 2609

Query: 862  TPTPGSVPSATQTQSTPTV-QAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPG 920
               P  +P      S P +   A+Q      P    + P      S      P    P  
Sbjct: 2610 LRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGM 2669

Query: 921  TPLSQ 925
            + LSQ
Sbjct: 2670 SGLSQ 2674



 Score = 54.7 bits (130), Expect = 1e-06
 Identities = 112/446 (25%), Positives = 160/446 (35%), Gaps = 91/446 (20%)

Query: 693  NVQLPQAPMGPR------AASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMM 746
            N+  PQ PM  R         P      + S   +PG+ I P+       + G    N  
Sbjct: 4151 NLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQ 4210

Query: 747  AQ--APAQSQ----FLPQNQFPSSSGAMSVGMGQPPA-QTGVSQG------QVPGAALPN 793
             +  +P Q Q     L Q Q   S         Q P  QT   QG      Q+ G   P 
Sbjct: 4211 LRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQ 4270

Query: 794  --PLNMLG----PQAS-QLPCPPVTQS------PLHPTPPPASTAAGMPSLQHTTPPGMT 840
              PL  LG    PQ   +LP PP   S      P+HPTPPP+S        Q  +P    
Sbjct: 4271 TGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQL 4330

Query: 841  PPQ-PAAPTQPSTPVSSSGQTPTPTPGSV-PSATQTQSTPTVQAAAQAQVTPQPQTPVQP 898
            P +    PT P TP    G T  P PG V P+A Q   T          +  +   P  P
Sbjct: 4331 PTEAQLPPTHPGTP-KPQGPTLEPPPGRVSPAAAQLADT----------LFSKGLGPWDP 4379

Query: 899  PS--VATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPV 956
            P     T +  Q    P H       L Q    +   VP  S ++      Q+P  +   
Sbjct: 4380 PDNLAETQKPEQSSLVPGH-------LDQVNGQV---VPEASQLSI----KQEPREEPCA 4425

Query: 957  LEMKTETQAEDTEP--DPGESK----GEPRSEMMEEDLQGASQVKEETDIAEQKSEPM-- 1008
            L  ++  +  + EP   PG S       PRSE     LQ   + K       + SE +  
Sbjct: 4426 LGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRA 4485

Query: 1009 ----EVDEKKPEVKVEVKEEEESSSNGTASQSTSPS------------QPRKKIFKPEEL 1052
                 +D K   ++ +++    +  +  A +  +P               RKK+ K + +
Sbjct: 4486 EINGHIDSKLAGLEQKLQGTPSNKEDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGV 4545

Query: 1053 R--QALMPTLEALYRQDPESLPFRQP 1076
            R  +AL+  L    +Q+   LP  +P
Sbjct: 4546 RASEALLKQL----KQELSLLPLTEP 4567



 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 100/384 (26%), Positives = 128/384 (33%), Gaps = 59/384 (15%)

Query: 648  PAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAAS 707
            P P  QP  + Q QP      PL LP  + Q    +++    S G  QL        ++ 
Sbjct: 4080 PQPQPQPSSL-QLQP------PLRLPGQQQQQVSLLHTAGGGSHG--QLGSGSSSEASSV 4130

Query: 708  PMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGA 767
            P   +    S+G  PG        PQ P +     NN   Q P     L        SG 
Sbjct: 4131 PHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVL-------QSGQ 4183

Query: 768  MSVGMGQPPAQTGVSQGQVPGAALPNP-LNMLGPQASQLPCPPVTQSPLHPTPPPASTAA 826
               G+G  P   G  + Q+ G    NP L  L PQ  Q     + Q  L  +     T  
Sbjct: 4184 GLPGVGIMPT-VGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPP 4242

Query: 827  GMPSLQHTTP----PGMTPPQPAAPTQPSTPVSSSGQTPTPT-PGSVPSATQTQSTPTVQ 881
                   T+P     G  P     P   + P+   G  P P  P  +P+     ST  V 
Sbjct: 4243 YQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPV- 4301

Query: 882  AAAQAQVTPQPQTPVQP--PSVATPQSSQQQPTPVHAQP--PGTPLSQAAASIDNRVPTP 937
                   TP P +P +P  PS   P  S Q PT     P  PGTP  Q         P P
Sbjct: 4302 -LGPVHPTPPPSSPQEPKRPS-QLPSPSSQLPTEAQLPPTHPGTPKPQG----PTLEPPP 4355

Query: 938  SSVASAETN------SQQPGPDVPVLEMKTETQAEDTEPDPG----------------ES 975
              V+ A         S+  GP  P   +    + E +   PG                  
Sbjct: 4356 GRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSI 4415

Query: 976  KGEPRSEMMEEDLQGASQVKEETD 999
            K EPR E       GA  VK E +
Sbjct: 4416 KQEPREEPC---ALGAQSVKREAN 4436



 Score = 52.0 bits (123), Expect = 7e-06
 Identities = 118/559 (21%), Positives = 189/559 (33%), Gaps = 43/559 (7%)

Query: 1844 LPSPTSAPPGTPTQQPSTPQTPQPPA-QPQPSPVSMSPAGFPSVARTQPPTTVS-TGKPT 1901
            LP P  +P   P ++  +P +P P A +  P P  +  +  P       P   S    P 
Sbjct: 441  LPPPEESPLSPPPEE--SPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPP 498

Query: 1902 SQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVS 1961
             + P  PPP   P + +E +     E           ++   PP      +P  + +P+S
Sbjct: 499  EESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLS---PPPEASPLSPPFEESPLS 555

Query: 1962 LNVPRPNQVSGPVMP-----SMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGP-RM 2015
               P P ++     P     S PP +   +P P++ PM   P P  S         P   
Sbjct: 556  ---PPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMS--PPPEASRLFPPFEESPLSP 610

Query: 2016 PSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQP 2075
            P  + P S  P A +       SP SP  ++  ++      +L    +  R +      P
Sbjct: 611  PPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESP 670

Query: 2076 GMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAM-------GGLNP 2128
             + P P  +  P   P       P  ++          P  PP + ++         L P
Sbjct: 671  -LSPPP--EESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLP 727

Query: 2129 QGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMA 2188
              +   +      P++ S  P+   +  R   ++     Q ++     Q     +     
Sbjct: 728  LPEEPQLCPRSEGPHL-SPRPEEPHLSPRP--EEPHLSPQAEEPHLSPQPEEPCLCAVPE 784

Query: 2189 GHGQFQQPQGPGGYPPAMQ---QQQRMQQHL-PLQGSSMGQMAAQMGQLG-QMGQPGLG- 2242
                  Q +GP   P   +     Q  + HL P+          +   L  Q  +P L  
Sbjct: 785  EPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSP 844

Query: 2243 ADSTPNIQQALQQRILQQQQMKQQIGSPGQ-PNPMSPQQHMLSGQPQASHLPGQQIATSL 2301
                 ++   L++  L  +  K     PGQ P P         G+P  S L G+   +  
Sbjct: 845  RPEESHLSPELEKPPLSPRPEKPP-EEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEP 903

Query: 2302 SNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSP-QTGSPHPGLAVTMASSIDQG 2360
                 SP P + P   S  P  SP   + P P P  +SP  T +  P L+         G
Sbjct: 904  GEPPLSPLPEELPLSPSGEPSLSPQ-LMPPDPLPPPLSPIITAAAPPALSPLGELEYPFG 962

Query: 2361 HLG--NPEQSAMLPQLNTP 2377
              G  +PE     P L TP
Sbjct: 963  AKGDSDPESPLAAPILETP 981



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 77/312 (24%), Positives = 119/312 (38%), Gaps = 47/312 (15%)

Query: 649  APGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFN----PMSLGNVQLPQAPM-GP 703
            +P  +P + PQ  P  P   PLS P+        ++       P        P++P+  P
Sbjct: 918  SPSGEPSLSPQLMPPDPLPPPLS-PIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAP 976

Query: 704  RAASPMNHSVQMNSMG--SVPGMAISPSRMPQPPNMMGAHTNNMMAQAP------AQSQF 755
               +P++   + N      VP M + PS    P + +G  +  +M   P       Q   
Sbjct: 977  ILETPISPPPEANCTDPEPVPPMILPPS----PGSPVGPASPILMEPLPPQCSPLLQHSL 1032

Query: 756  LPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLN-MLGPQASQLPCPPVTQSP 814
            +PQN  PS     ++ +  P   + +  G+V G +    L+ M   + S+  CP +  S 
Sbjct: 1033 VPQNSPPSQCSPPALPLSVPSPLSPI--GKVVGVSDEAELHEMETEKVSEPECPALEPSA 1090

Query: 815  LHPTPPPASTAAGMPSLQHTTPPGMTPPQPA--------APTQPSTPVSSSGQTPTP--T 864
              P P P      M  L    P     P PA          T P   + + G  P P  T
Sbjct: 1091 TSPLPSP------MGDLSCPAP----SPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQT 1140

Query: 865  PGSVPSATQTQSTPTVQAAAQ-AQVTPQPQTP--VQPPSVATPQSSQQQP-TPVHAQPPG 920
            PGS+  A++ + +P +    + A VTP    P   Q     +P   Q++P  PV   PP 
Sbjct: 1141 PGSL--ASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPT 1198

Query: 921  TPLSQAAASIDN 932
               S     I N
Sbjct: 1199 LIKSDIVNEISN 1210



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 79/368 (21%), Positives = 133/368 (36%), Gaps = 46/368 (12%)

Query: 645 PALPAPGAQ---PPVIPQAQPVRPP--NGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQA 699
           P  P P A    PP  P+  P+ PP    P+S P    ++       +P+S    + P +
Sbjct: 562 PTSPPPEASRLSPP--PEESPMSPPPEESPMSPPPEASRLFPPFEE-SPLSPPPEESPLS 618

Query: 700 PMGPRAASPMNHSVQMNSMGSVPGMA-ISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQ 758
           P  P  AS ++   + + M   P  + +SP   P+   +      + ++  P +S   P 
Sbjct: 619 P--PPEASRLSPPPEDSPMSPPPEESPMSPP--PEVSRLSPLPVVSRLSPPPEESPLSPP 674

Query: 759 -NQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGP----QASQLPCP----- 808
             + P+S    +  +  PP  +  S       A P P + L      ++  LP P     
Sbjct: 675 PEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQL 734

Query: 809 -PVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTP---PQP------AAPTQPSTPVSSSG 858
            P ++ P     P     +  P   H +P    P   PQP      A P +P     + G
Sbjct: 735 CPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEG 794

Query: 859 QTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQT----PVQPPSVATPQSSQQQPTPV 914
              +P P  +  + QT+         +  ++PQP+     P       +P+  +   +P 
Sbjct: 795 PHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPE 854

Query: 915 HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGE 974
             +PP +P  +       + P P  +         P P  P L   +    E    +PGE
Sbjct: 855 LEKPPLSPRPEKPPEEPGQCPAPEELPLF------PPPGEPSL---SPLLGEPALSEPGE 905

Query: 975 SKGEPRSE 982
               P  E
Sbjct: 906 PPLSPLPE 913



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 124/556 (22%), Positives = 186/556 (33%), Gaps = 104/556 (18%)

Query: 1843 SLPSPTSAPPGTPTQQPSTPQT--PQPPAQPQPSPVSMSPAGFPSVARTQPPTT------ 1894
            S   P + PP TP  QP  P++    PP      P S  PA   S + +Q P T      
Sbjct: 2373 SYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSA 2432

Query: 1895 --VSTGKPTSQVPAPPPPAQPP--PAAVEAARQIEREAQQQQ--------HLYRVNINNS 1942
                    T +  +P P ++PP  P + +    + +  + Q          L   ++   
Sbjct: 2433 EAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAG 2492

Query: 1943 MPPGRTGMGTPGSQMAPVSLNVPRPNQVSGP------VMPSMPPGQWQQA----PLPQQQ 1992
              P     G  G   A V    P PN V  P        PS     + QA     L    
Sbjct: 2493 GFPAALPAGPAGELHAKVPSGQP-PNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPV 2551

Query: 1993 PMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQ----QQQV 2048
            P PGLP P        +  GP  P++  P+S + +          SP  P      +   
Sbjct: 2552 PQPGLPPP----HGINSHFGPG-PTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYG 2606

Query: 2049 LNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQ 2108
            L+ L+  P ++       +  Y+++  G   + G+ S    +  PG     SL       
Sbjct: 2607 LSPLRP-PSVLPPPAPDGSLPYLSH--GASQRSGITSPVEKREDPGTGMGSSL------- 2656

Query: 2109 AGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQ 2168
            A    PG   Q   M GL                +   +  Q +    R+LL +QQ Q+ 
Sbjct: 2657 ATAELPGT--QDPGMSGL----------------SQTELEKQRQRQRLRELLIRQQIQRN 2698

Query: 2169 QQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAA 2228
              +Q+++    +AG  G     G   +P       PA +Q  R Q   P  G+       
Sbjct: 2699 TLRQEKETAAAAAGAVGPPGSWG--AEPSS-----PAFEQLSRGQ--TPFAGTQDKSSLV 2749

Query: 2229 QMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQ 2288
             +    ++  P LG  S P+                 +   P  P+ M      L G  Q
Sbjct: 2750 GLPP-SKLSGPILGPGSFPS------------DDRLSRPPPPATPSSMDVNSRQLVGGSQ 2796

Query: 2289 ASH--------LPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVS- 2339
            A +        LP QQ    L  Q ++ A        S    S+P P +  Q     ++ 
Sbjct: 2797 AFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAG 2856

Query: 2340 -----PQTGSPHPGLA 2350
                 P  G P PG A
Sbjct: 2857 ISTRLPGPGEPVPGPA 2872



 Score = 45.8 bits (107), Expect = 5e-04
 Identities = 63/282 (22%), Positives = 96/282 (34%), Gaps = 50/282 (17%)

Query: 704  RAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPS 763
            +A S +N   ++  +           R+P  P  +G+        A A + F+     P+
Sbjct: 2079 QAESQINKQTKVGDIARKTDRPALHLRIPPQPGALGSPP-----PAAAPTIFIGSPTTPA 2133

Query: 764  SSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNM-LGPQA-SQLP-------CPPVTQSP 814
                 + G  +PPA      G VPG   P  L + L PQ  +Q+P        P     P
Sbjct: 2134 GLSTSADGFLKPPA------GSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEP 2187

Query: 815  LHPTPPP---------------------ASTAAGMPSLQHTTPPGMTPPQPAAP---TQP 850
              PT PP                     +   AG P   HTTPPG    QP+ P    +P
Sbjct: 2188 RFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKP 2247

Query: 851  STPVSSSGQTP-TPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQ 909
              P   +   P +P  G   ++    S P    + +A    + +     PS   P     
Sbjct: 2248 RCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGF- 2306

Query: 910  QPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPG 951
                V +   GT L        +    P +  +++   Q PG
Sbjct: 2307 ----VDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPG 2344



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 134/637 (21%), Positives = 202/637 (31%), Gaps = 152/637 (23%)

Query: 444  QRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMN-------IPAG 496
            Q+ +  L   Y N+ Q Q Q     QQ  Q Q H  +  L+P  +  +        +P  
Sbjct: 3585 QKEHTNLMAEYRNKQQQQQQ-----QQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGH 3639

Query: 497  GITTDQQPPN--------LISESALPTSLGATNPLMNDG-------SNSGNIGTLSTIPT 541
            G+   Q PP              ALP   G   P +N          +SG  G+L+    
Sbjct: 3640 GLQPPQGPPGGQAGGLRLTPGGMALPGQPGG--PFLNTALAQQQQQQHSGGAGSLAGPSG 3697

Query: 542  AAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGD 601
               P +  +R                          PD   L++R+++ L     ++   
Sbjct: 3698 GFFPGNLALRS-----------------------LGPDSRLLQERQLQ-LQQQRMQLAQK 3733

Query: 602  MYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAP-GAQPP----- 655
            + +    + +  HLL +   + Q++            G+  NQ   P P G  PP     
Sbjct: 3734 LQQQQQQQQQQQHLLGQVAIQQQQQ---------QGPGVQTNQALGPKPQGLMPPSSHQG 3784

Query: 656  -VIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGN--------------------V 694
             ++ Q  P +PP GP  + +   QV+  +   +P +LG                      
Sbjct: 3785 LLVQQLSP-QPPQGPQGM-LGPAQVAV-LQQQHPGALGPQGPHRQVLMTQSRVLSSPQLA 3841

Query: 695  QLPQAPMGPR--AASPMNHSVQMNSMGSVPGMA------ISPSRMP----QPPNMMGAHT 742
            Q  Q  MG R   A       Q    GS+ G++      +S S  P    QP   +    
Sbjct: 3842 QQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQ 3901

Query: 743  NNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQA 802
                 Q   Q Q   Q Q           + Q   Q  + Q Q     L      L  Q 
Sbjct: 3902 QQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQ--QLQQQQQQLQQQQ 3959

Query: 803  SQ----------------LPCPPVTQSPLHPTPPPASTAAGMPS--LQHTTPPGMTPPQP 844
             Q                L       SP        +   GMP+  LQH + PG   P  
Sbjct: 3960 QQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTL 4019

Query: 845  AAPTQPST---PVSSSGQTPTPTP--------GSVPSATQTQ--------STPTVQAAAQ 885
                +      P  SS  T  P+         G+ P +  T+        S  +     Q
Sbjct: 4020 LLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQ 4079

Query: 886  AQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQ------PPGTPLSQAAASIDNRVPTPSS 939
             Q  PQP +    P +  P   QQQ + +H          G+  S  A+S+ + +  PS 
Sbjct: 4080 PQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSV 4139

Query: 940  VASAETNSQQP---GPDVPVLEMKTETQAEDTEPDPG 973
                +  S      GP  P+LE   +       P PG
Sbjct: 4140 SLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPG 4176



 Score = 42.7 bits (99), Expect = 0.004
 Identities = 97/419 (23%), Positives = 151/419 (36%), Gaps = 114/419 (27%)

Query: 617  AEKIYKIQKELEEKRRSRLHKQGILGN------QPAL-----PAPGA--QPPVIPQAQPV 663
            A +I K+QK+ E    S+++KQ  +G+      +PAL     P PGA   PP      P 
Sbjct: 2070 AHRINKVQKQAE----SQINKQTKVGDIARKTDRPALHLRIPPQPGALGSPP------PA 2119

Query: 664  RPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSM---GS 720
              P   +  P     +S   + F     G+V  P +P       P     Q+ S    G 
Sbjct: 2120 AAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGL 2179

Query: 721  VPGMAI---------------SPSRMPQPPNMMGAHTNNMMAQA-------PAQSQFLPQ 758
             P   +               SP+  P  P M+GA +     Q        P   +  P 
Sbjct: 2180 APAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPS 2239

Query: 759  NQ---------------FPSSSGAMSVGMGQP---PAQTGVSQGQVP------GAALPN- 793
                              P S G       +P   P   G S+  +       GA+ P+ 
Sbjct: 2240 TPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSY 2299

Query: 794  ---PLNMLGPQAS-------QLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQ 843
                L  +   +S       +L  P V ++PL P        +    L+   PP   P Q
Sbjct: 2300 GPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPP---PAQ 2356

Query: 844  PAAPTQPS----------------TPVSSSGQTPTP------TPGSVPS--ATQTQSTPT 879
              AP+ PS                 P++   Q P P       P S+PS   ++  ++P 
Sbjct: 2357 ALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQ 2416

Query: 880  VQAAAQAQVTPQP-QTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTP 937
             Q+++Q+ +TP+P       PS  TP+   Q P P +++PP  P S+   +  ++ P P
Sbjct: 2417 SQSSSQSPLTPRPLSAEAFCPSPVTPRF--QSPDP-YSRPPSRPQSRDPFAPLHKPPRP 2472



 Score = 42.7 bits (99), Expect = 0.004
 Identities = 56/212 (26%), Positives = 88/212 (41%), Gaps = 37/212 (17%)

Query: 2177 QQGSAGMAGGMAGHGQFQQP-QGPGGYPPAMQQQQRMQQHLPLQGSSM---GQMAAQMGQ 2232
            ++ S G  GG   H     P  GPGG          + +   L+  ++   G  AA   +
Sbjct: 3181 EKASFGATGGPPAHLLTPSPLSGPGG--------SSLLEKFELESGALTLPGGPAASGDE 3232

Query: 2233 LGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGS---PGQPNPMSPQQHMLSGQP-- 2287
            L +M +  L A   P + + L +   ++ Q KQQ+ +   P Q      QQH L   P  
Sbjct: 3233 LDKM-ESSLVASELPLLIEDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHSLLSAPGP 3291

Query: 2288 -QASHLPGQQIATSL--SNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGS 2344
             QA  LP +  + SL  S Q  S     + +P        P P +  QP  H +  +   
Sbjct: 3292 AQAMSLPHEGSSPSLAGSQQQLSLGLAGARQP------GLPQPLMPTQPPAHALQQR--- 3342

Query: 2345 PHPGLAVTMASSIDQGHLGNPE---QSAMLPQ 2373
                LA +MA   +QGH+ + +   Q+ ++PQ
Sbjct: 3343 ----LAPSMAMVSNQGHMLSGQHGGQAGLVPQ 3370



 Score = 39.7 bits (91), Expect = 0.036
 Identities = 89/397 (22%), Positives = 137/397 (34%), Gaps = 85/397 (21%)

Query: 644  QPALPAPGAQPP-----------VIPQAQPVR---------PPNGPLSLPVNRMQVSQGM 683
            +P +P PG  PP            + + Q            P   PL         S G+
Sbjct: 2548 KPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGL 2607

Query: 684  NSFNPMSL-----GNVQLPQAPMGPRAASPMNHSVQMNS-MGSVPGMAISPSRMP--QPP 735
            +   P S+      +  LP    G    S +   V+     G+  G +++ + +P  Q P
Sbjct: 2608 SPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDP 2667

Query: 736  NMMGAHTNNMMAQAPAQS-------QFLPQN---QFPSSSGAMSVGMGQP---------P 776
             M G     +  Q   Q        Q + +N   Q   ++ A +  +G P         P
Sbjct: 2668 GMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSP 2727

Query: 777  AQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTP 836
            A   +S+GQ P A   +  +++G   S+L  P      L P   P+      P      P
Sbjct: 2728 AFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPI-----LGPGSFPSDDRLSRP------P 2776

Query: 837  PGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPV 896
            P  TP      ++     S +     P PGS+P   Q Q     Q  A A  + +     
Sbjct: 2777 PPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQL-WQQQQATAATSMRFAMSA 2835

Query: 897  QPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPV 956
            + PS   P+  +        Q  G+PL    A I  R+P P            PGP  P 
Sbjct: 2836 RFPSTPGPELGR--------QALGSPL----AGISTRLPGPGEPV--------PGPAGPA 2875

Query: 957  --LEMKTETQ---AEDTEPDPGESKGE-PRSEMMEED 987
              +E++   Q        P PG+   + PR   + ED
Sbjct: 2876 QFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSED 2912



 Score = 39.3 bits (90), Expect = 0.047
 Identities = 92/487 (18%), Positives = 165/487 (33%), Gaps = 80/487 (16%)

Query: 611  EYYHLLAEKIYKIQKELEEKRRSRLHKQGILG--------NQPALPAPGAQPPVIPQAQP 662
            E   L+ E+  KIQK+L++ R+ +     ++          Q        Q   +    P
Sbjct: 3562 EKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSP 3621

Query: 663  VRPPN------GPLSLPVNRMQVSQGMNSFNPMSL----GNVQLPQAPMGPRAASPMNHS 712
             + P       G L LP + +Q  QG        L    G + LP  P GP   + +   
Sbjct: 3622 SQSPRLLTKLPGQL-LPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQ 3680

Query: 713  VQMNSMGSVPGMA---------------ISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLP 757
             Q    G    +A               + P         +      M      Q Q   
Sbjct: 3681 QQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQ 3740

Query: 758  QNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHP 817
            Q Q     G +++   Q     GV   Q  G   P P  ++ P + Q     +    L P
Sbjct: 3741 QQQQQHLLGQVAIQQQQQQG-PGVQTNQALG---PKPQGLMPPSSHQ----GLLVQQLSP 3792

Query: 818  TPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQST 877
             PP               P GM  P   A  Q   P +   Q P            TQS 
Sbjct: 3793 QPPQG-------------PQGMLGPAQVAVLQQQHPGALGPQGPH------RQVLMTQS- 3832

Query: 878  PTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTP 937
               +  +  Q+  Q Q  +    V   Q  QQQ         G  LS    S+ +    P
Sbjct: 3833 ---RVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAG--LSHLQQSLMSHSGQP 3887

Query: 938  SSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEE 997
                     S QP   +  L+ + + Q +       + + + + ++ ++ LQ   Q ++ 
Sbjct: 3888 KL-------SAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQL 3940

Query: 998  TDIAEQ--KSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQA 1055
                +Q  + +  ++ +++ + + + +++++    G  +QS +   P+++    ++ + A
Sbjct: 3941 QQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQ----QQQQVA 3996

Query: 1056 LMPTLEA 1062
            L P + A
Sbjct: 3997 LGPGMPA 4003



 Score = 38.9 bits (89), Expect = 0.062
 Identities = 94/438 (21%), Positives = 148/438 (33%), Gaps = 86/438 (19%)

Query: 468  GQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDG 527
            G  P  P  + Q+ T N L N P             PP+ +  +  P+       ++N  
Sbjct: 4598 GALPTGPDYYSQLLTKNNLSNPPT------------PPSSLPPTPPPS---VQQKMVNGV 4642

Query: 528  SNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRR 587
            + S  +G       +A  S   +R       T +++S      + A  PTP     +D R
Sbjct: 4643 TPSEELGEHPKDAASARDSERALRD------TSEVKS----LDLLAALPTPPHNQTEDVR 4692

Query: 588  MENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPAL 647
            ME+        + D  +S         +L E+  +          S   +Q      P +
Sbjct: 4693 MES------DEDSDSPDSIVPASSPESILGEEAPRFPH-----LGSGRWEQEDRALSPVI 4741

Query: 648  PA-PGAQPPVIPQAQPVRPPN--GPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPR 704
            P  P A  PV P  +P        P  LPV   +  +G      +++             
Sbjct: 4742 PLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVS------------ 4789

Query: 705  AASPMNHSVQMNSMGSVPGMAISPSR---MPQPPNMMGAHTNNMMAQAPAQSQFLPQNQF 761
            AA+  N +  M ++  +  M I  S     P+ P   G       A+ P   +   + + 
Sbjct: 4790 AAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKS 4849

Query: 762  PSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLG--PQASQLPCPPVTQS------ 813
            P +           P         +PG  L + L++L    Q S  P PP   S      
Sbjct: 4850 PDTG----------PDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVS 4899

Query: 814  -----------PLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAA--PTQPSTPVSSSGQT 860
                       P  P+PPP S  A  P+   T P    P +P A  P     P++SS ++
Sbjct: 4900 NLDVRQLSAPPPEEPSPPP-SPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPES 4958

Query: 861  PTPTPGSVPSATQTQSTP 878
              P P + P      S P
Sbjct: 4959 ARPKPRARPPEEGEDSRP 4976



 Score = 37.7 bits (86), Expect = 0.14
 Identities = 95/463 (20%), Positives = 144/463 (31%), Gaps = 112/463 (24%)

Query: 1868 PAQPQPSPVSMSPAGFPSVARTQP---PTTVSTGKPTS--QVPAPPPPAQPPPAAVEAAR 1922
            P  P+  P   + A  P +A   P   P     G+  S  Q     P  +P PAA     
Sbjct: 3093 PLGPEERPPPAADASEPRLASVLPEVKPKVEEGGRHPSPCQFTIATPKVEPAPAAN---- 3148

Query: 1923 QIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMA--PVSLNVPRPNQVSGPVMPSMPP 1980
                           ++   + PG++ MG+  ++M   P S +     + S       P 
Sbjct: 3149 ---------------SLGLGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPA 3193

Query: 1981 GQWQQAPLPQQQPMPG---------LPRPVISMQAQAAVAGPRMPSVQPPRSIS--PSAL 2029
                 +PL      PG         L    +++    A +G  +  ++     S  P  +
Sbjct: 3194 HLLTPSPLSG----PGGSSLLEKFELESGALTLPGGPAASGDELDKMESSLVASELPLLI 3249

Query: 2030 QDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGM 2089
            +DLL   K     +QQ      L +  Q      +Q+    + + PG      L  +   
Sbjct: 3250 EDLLEHEKKELQKKQQ------LSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSS 3303

Query: 2090 QPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNP 2149
                G  QQ SL    A Q G+P+P +P Q                  P H         
Sbjct: 3304 PSLAGSQQQLSLGLAGARQPGLPQPLMPTQP-----------------PAH--------- 3337

Query: 2150 QYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAM--- 2206
                 L+++L         Q      Q  G AG+    +      Q +  G  PP+M   
Sbjct: 3338 ----ALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLSQ-KPMGTMPPSMCMK 3392

Query: 2207 QQQQRMQQHLP-----------------LQGSSMGQMAAQMGQLGQMGQPGLGADSTPNI 2249
             QQ  MQQ L                  +   +  +M A  G    M Q  +G     N 
Sbjct: 3393 PQQLAMQQQLANSFFPDTDLDKFAAEDIIDPIAKAKMVALKGIKKVMAQGSIGVAPGMNR 3452

Query: 2250 QQA--------------LQQRILQQQQMKQQIGSPGQPNPMSP 2278
            QQ               LQ  +      ++  G P QP P  P
Sbjct: 3453 QQVSLLAQRLSGGPSSDLQNHVAAGSGQERSAGDPSQPRPNPP 3495



 Score = 37.7 bits (86), Expect = 0.14
 Identities = 53/242 (21%), Positives = 88/242 (36%), Gaps = 35/242 (14%)

Query: 745  MMAQAPAQSQFLP-QNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQAS 803
            + A  PAQ+  LP +   PS +G+      Q     G++  + PG  LP PL    P A 
Sbjct: 3286 LSAPGPAQAMSLPHEGSSPSLAGS------QQQLSLGLAGARQPG--LPQPLMPTQPPAH 3337

Query: 804  QLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTP 863
             L      Q  L P+    S    M S QH    G+ P Q + P     P+ +   +   
Sbjct: 3338 AL------QQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLSQKPMGTMPPSMCM 3391

Query: 864  TPGSVPSATQTQS-----TPTVQAAAQAQVTPQPQTPV-----------QPPSVATPQSS 907
             P  +    Q  +     T   + AA+  + P  +  +           Q      P  +
Sbjct: 3392 KPQQLAMQQQLANSFFPDTDLDKFAAEDIIDPIAKAKMVALKGIKKVMAQGSIGVAPGMN 3451

Query: 908  QQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAED 967
            +QQ + +  +  G P    ++ + N V   S    +  +  QP P+ P        +A+ 
Sbjct: 3452 RQQVSLLAQRLSGGP----SSDLQNHVAAGSGQERSAGDPSQPRPNPPTFAQGVINEADQ 3507

Query: 968  TE 969
             +
Sbjct: 3508 RQ 3509



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 20/61 (32%), Positives = 26/61 (42%), Gaps = 2/61 (3%)

Query: 1840 PQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGK 1899
            P    PSP S PP  P  +  T    +PP  P P P++ SP       R +PP      +
Sbjct: 4918 PSPLAPSPAS-PPTEPLVELPTEPLAEPPV-PSPLPLASSPESARPKPRARPPEEGEDSR 4975

Query: 1900 P 1900
            P
Sbjct: 4976 P 4976



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 26/90 (28%), Positives = 36/90 (40%), Gaps = 9/90 (10%)

Query: 1833 TMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPP 1892
            T N  N+  + L +P   PP  P+  PS P  P P + P    V +     P+    +PP
Sbjct: 4895 TYNVSNLDVRQLSAP---PPEEPSPPPS-PLAPSPASPPTEPLVEL-----PTEPLAEPP 4945

Query: 1893 TTVSTGKPTSQVPAPPPPAQPPPAAVEAAR 1922
                    +S   A P P   PP   E +R
Sbjct: 4946 VPSPLPLASSPESARPKPRARPPEEGEDSR 4975



 Score = 31.6 bits (70), Expect = 9.8
 Identities = 25/99 (25%), Positives = 39/99 (39%), Gaps = 11/99 (11%)

Query: 859  QTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQ-------QQP 911
            ++P P P +  S T   S   V+  +     P P+ P  PPS   P  +        + P
Sbjct: 4882 ESPAPEPPTQHSYTYNVSNLDVRQLS----APPPEEPSPPPSPLAPSPASPPTEPLVELP 4937

Query: 912  TPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQP 950
            T   A+PP       A+S ++  P P +    E    +P
Sbjct: 4938 TEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRP 4976


>gi|7657218 bromodomain-containing protein 4 isoform short [Homo
            sapiens]
          Length = 722

 Score = 95.5 bits (236), Expect = 6e-19
 Identities = 84/304 (27%), Positives = 130/304 (42%), Gaps = 51/304 (16%)

Query: 859  QTPTPTPG--SVPSATQTQSTPTVQAAAQ----AQVTPQPQTPVQPPSVA-TPQSSQQQP 911
            +T T  PG  +VP+ TQ  + P  Q         Q TP P   V P  +  TP  +   P
Sbjct: 185  ETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPP 244

Query: 912  TPVHAQPPGTPLSQAAASIDNRVPTPSSVASAE---TNSQQPGPDVPVLEMKTETQAEDT 968
             P+   PP  P  Q   +     P P  V S       + QP      ++ K +T    T
Sbjct: 245  QPLQTPPPVPPQPQPPPA-----PAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTT 299

Query: 969  -EP--DPGESKGEPRSEMMEEDLQGASQVKE-ETDIAEQKSEPMEVDEKKPEVKVEVKEE 1024
             +P  +P     EP++  + +  + +  VK  + D+ + +  P       PE   +V E+
Sbjct: 300  IDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPA------PEKSSKVSEQ 353

Query: 1025 EESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGI 1084
             +  S                      + + +     A Y     + PF +PVD + LG+
Sbjct: 354  LKCCSG---------------------ILKEMFAKKHAAY-----AWPFYKPVDVEALGL 387

Query: 1085 PDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLA 1144
             DY DI+K+PMD+STIK KL+  +Y++  ++  DV LMF+N + YN     V     KL 
Sbjct: 388  HDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQ 447

Query: 1145 EVFE 1148
            +VFE
Sbjct: 448  DVFE 451



 Score = 78.2 bits (191), Expect = 9e-14
 Identities = 43/159 (27%), Positives = 85/159 (53%), Gaps = 13/159 (8%)

Query: 1016 EVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQ 1075
            + + + +    +S+N    ++++P++P+++     +L+  L   L+ L++    + PF+Q
Sbjct: 30   QAQAQPQPANAASTNPPPPETSNPNKPKRQT---NQLQYLLRVVLKTLWKHQ-FAWPFQQ 85

Query: 1076 PVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSR 1135
            PVD   L +PDY+ I+K PMD+ TIK++L+   Y    + + D   MF N ++YN+    
Sbjct: 86   PVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDD 145

Query: 1136 VYKFCSKLAEVFEQEIDP---------VMQSLGYCCGRK 1165
            +      L ++F Q+I+          ++Q+ G   GRK
Sbjct: 146  IVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRK 184



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 31/76 (40%), Positives = 35/76 (46%), Gaps = 9/76 (11%)

Query: 1849 SAPPGTPT----QQPSTPQTPQPPAQPQPSPVSMSPAGFPSVART----QPPTTVSTGKP 1900
            +A PG  T     Q STP   Q P QP P PV  +P  FP+V        P  TV   +P
Sbjct: 188  TAKPGVSTVPNTTQASTPPQTQTP-QPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQP 246

Query: 1901 TSQVPAPPPPAQPPPA 1916
                P  PP  QPPPA
Sbjct: 247  LQTPPPVPPQPQPPPA 262



 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 57/247 (23%), Positives = 86/247 (34%), Gaps = 45/247 (18%)

Query: 745 MMAQAPAQSQFLPQNQFPSSSGAMSV----GMGQPPAQTGVSQGQVPGAALPNPLNMLGP 800
           +MA+A  +      N+ P+    + +    G G+   +TG ++  V  + +PN      P
Sbjct: 148 LMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGV--STVPNTTQASTP 205

Query: 801 QASQLPCP--PVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSG 858
             +Q P P  P  Q+  HP P           +    PP      P  P QP  P     
Sbjct: 206 PQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPP----- 260

Query: 859 QTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQP 918
             P P P  V      QS P + AA     TPQP    +        ++     P+H +P
Sbjct: 261 --PAPAPQPV------QSHPPIIAA-----TPQPVKTKKGVKRKADTTTPTTIDPIH-EP 306

Query: 919 PGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGE 978
           P  P       +  R  +   V       + P  DVP           D++  P   K  
Sbjct: 307 PSLPPEPKTTKLGQRRESSRPV-------KPPKKDVP-----------DSQQHPAPEKSS 348

Query: 979 PRSEMME 985
             SE ++
Sbjct: 349 KVSEQLK 355



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 27/78 (34%), Positives = 30/78 (38%), Gaps = 11/78 (14%)

Query: 1845 PSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTG------ 1898
            P  T  PP      P  P  PQPP  P P PV   P   P +A T  P     G      
Sbjct: 237  PVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHP---PIIAATPQPVKTKKGVKRKAD 293

Query: 1899 --KPTSQVPAPPPPAQPP 1914
               PT+  P   PP+ PP
Sbjct: 294  TTTPTTIDPIHEPPSLPP 311



 Score = 38.9 bits (89), Expect = 0.062
 Identities = 21/56 (37%), Positives = 33/56 (58%), Gaps = 3/56 (5%)

Query: 1516 KELEQEEEERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPS 1571
            K+ E++++E+KKE+     E  E  +     AK+   KKT KN SS S  +KK+P+
Sbjct: 537  KKKEKDKKEKKKEKHKRKEEVEENKK---SKAKEPPPKKTKKNNSSNSNVSKKEPA 589



 Score = 35.8 bits (81), Expect = 0.52
 Identities = 25/101 (24%), Positives = 36/101 (35%), Gaps = 8/101 (7%)

Query: 1839 VPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQ--------PSPVSMSPAGFPSVARTQ 1890
            VP Q  P P  AP    +  P    TPQP    +         +P ++ P   P     +
Sbjct: 253  VPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPE 312

Query: 1891 PPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQ 1931
            P TT    +  S  P  PP    P +    A +   +  +Q
Sbjct: 313  PKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQ 353



 Score = 33.1 bits (74), Expect = 3.4
 Identities = 31/106 (29%), Positives = 40/106 (37%), Gaps = 16/106 (15%)

Query: 2242 GADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSL 2301
            G  + PN  QA             Q  +P QPNP   Q    +  P  +  P   + T +
Sbjct: 192  GVSTVPNTTQA---------STPPQTQTP-QPNPPPVQA---TPHPFPAVTPDLIVQTPV 238

Query: 2302 SNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHP 2347
               V  P P+Q+P P   PP   P P   PQP   H      +P P
Sbjct: 239  MTVV-PPQPLQTPPP--VPPQPQPPPAPAPQPVQSHPPIIAATPQP 281



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 26/130 (20%), Positives = 46/130 (35%), Gaps = 9/130 (6%)

Query: 916  AQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGES 975
            A+ P  P     A     VP P+ V +  ++S               +   D+  D  E 
Sbjct: 455  AKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDS---------SSDSDSSTDDSEE 505

Query: 976  KGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQ 1035
            +   R   ++E L+   +        +Q     +  +KK + K + K +EE   N  +  
Sbjct: 506  ERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKA 565

Query: 1036 STSPSQPRKK 1045
               P +  KK
Sbjct: 566  KEPPPKKTKK 575


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
            sapiens]
          Length = 1362

 Score = 95.5 bits (236), Expect = 6e-19
 Identities = 84/304 (27%), Positives = 130/304 (42%), Gaps = 51/304 (16%)

Query: 859  QTPTPTPG--SVPSATQTQSTPTVQAAAQ----AQVTPQPQTPVQPPSVA-TPQSSQQQP 911
            +T T  PG  +VP+ TQ  + P  Q         Q TP P   V P  +  TP  +   P
Sbjct: 185  ETGTAKPGVSTVPNTTQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPP 244

Query: 912  TPVHAQPPGTPLSQAAASIDNRVPTPSSVASAE---TNSQQPGPDVPVLEMKTETQAEDT 968
             P+   PP  P  Q   +     P P  V S       + QP      ++ K +T    T
Sbjct: 245  QPLQTPPPVPPQPQPPPA-----PAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTT 299

Query: 969  -EP--DPGESKGEPRSEMMEEDLQGASQVKE-ETDIAEQKSEPMEVDEKKPEVKVEVKEE 1024
             +P  +P     EP++  + +  + +  VK  + D+ + +  P       PE   +V E+
Sbjct: 300  IDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPDSQQHPA------PEKSSKVSEQ 353

Query: 1025 EESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGI 1084
             +  S                      + + +     A Y     + PF +PVD + LG+
Sbjct: 354  LKCCSG---------------------ILKEMFAKKHAAY-----AWPFYKPVDVEALGL 387

Query: 1085 PDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLA 1144
             DY DI+K+PMD+STIK KL+  +Y++  ++  DV LMF+N + YN     V     KL 
Sbjct: 388  HDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQ 447

Query: 1145 EVFE 1148
            +VFE
Sbjct: 448  DVFE 451



 Score = 81.6 bits (200), Expect = 8e-15
 Identities = 126/509 (24%), Positives = 169/509 (33%), Gaps = 87/509 (17%)

Query: 605  SANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGI------LGNQPALPAPGAQPPVIP 658
            S++S D    +  +   K     E+K+    H Q +      +  QP  P P  QPP  P
Sbjct: 711  SSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQP--PPPPQQPPPPP 768

Query: 659  QAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGN---VQLPQAPMGPRAASPMNHSVQM 715
              Q  + P  P   P    Q +  M S  P  +     V  PQ P       P+ H  Q 
Sbjct: 769  PPQQQQQPPPPPPPPSMPQQAAPAMKSSPPPFIATQVPVLEPQLP--GSVFDPIGHFTQP 826

Query: 716  NSMGSVPGMAISPSRMPQPP-NMMGAHTN-NMMAQAPAQSQFLPQNQFPSSSGAMSVGMG 773
                  P +   P  +PQPP +    H N + +   PA    LPQ               
Sbjct: 827  ILHLPQPEL---PPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQ--------------- 868

Query: 774  QPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSP---LHPTPPPASTAAGMPS 830
            QP   +  +    P  A P  ++    Q   LP PP+ Q P   L    PPA     M  
Sbjct: 869  QPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQM 928

Query: 831  LQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTP 890
              +     +   QP  P  PS  V S    P P P            P+VQ   Q Q  P
Sbjct: 929  QLYLQQ--LQKVQPPTPLLPSVKVQSQPPPPLPPP----------PHPSVQQQLQQQPPP 976

Query: 891  QPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQP 950
             P    QPP     Q  Q  P PVH QP      Q +  I    P            QQP
Sbjct: 977  PPPPQPQPP---PQQQHQPPPRPVHLQP-----MQFSTHIQQPPPPQGQQPPHPPPGQQP 1028

Query: 951  GPDVPVLEMKTETQAEDTEPDPGESKGEPRS-----EMMEEDLQGASQVKEETDIAEQKS 1005
             P  P        Q       P   K +P S     E     +  + Q+ +   +  Q  
Sbjct: 1029 PPPQPA----KPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSP 1084

Query: 1006 EPMEVDEKKPEVK---------VEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQAL 1056
                V  KK E++         + V +EE+  S    S+  SPS   +    PE ++   
Sbjct: 1085 PQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKA-- 1142

Query: 1057 MPTLEALYRQDPESLPFRQPVDPQLLGIP 1085
                       P  LP R  + P  +G P
Sbjct: 1143 -----------PVHLPQRPEMKPVDVGRP 1160



 Score = 78.2 bits (191), Expect = 9e-14
 Identities = 43/159 (27%), Positives = 85/159 (53%), Gaps = 13/159 (8%)

Query: 1016 EVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQ 1075
            + + + +    +S+N    ++++P++P+++     +L+  L   L+ L++    + PF+Q
Sbjct: 30   QAQAQPQPANAASTNPPPPETSNPNKPKRQT---NQLQYLLRVVLKTLWKHQ-FAWPFQQ 85

Query: 1076 PVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSR 1135
            PVD   L +PDY+ I+K PMD+ TIK++L+   Y    + + D   MF N ++YN+    
Sbjct: 86   PVDAVKLNLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDD 145

Query: 1136 VYKFCSKLAEVFEQEIDP---------VMQSLGYCCGRK 1165
            +      L ++F Q+I+          ++Q+ G   GRK
Sbjct: 146  IVLMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRK 184



 Score = 78.2 bits (191), Expect = 9e-14
 Identities = 103/440 (23%), Positives = 156/440 (35%), Gaps = 85/440 (19%)

Query: 1817 IQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPS-- 1874
            +Q +L   QL + +  T    +V  QS P P   PP  P+ Q    Q P PP  PQP   
Sbjct: 926  MQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQLQQQPPPPPPPQPQPP 985

Query: 1875 ----------PVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQI 1924
                      PV + P  F +  +  PP       P  Q P  PPP Q PP    A  Q 
Sbjct: 986  PQQQHQPPPRPVHLQPMQFSTHIQQPPP-------PQGQQPPHPPPGQQPPPPQPAKPQ- 1037

Query: 1925 EREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQ 1984
                Q  QH +    + S P       T   + AP  L +  P       +    P Q  
Sbjct: 1038 ----QVIQHHHSPRHHKSDP-----YSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQN 1088

Query: 1985 QAPLPQQ-------QPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLK 2037
              P  Q+       QP P +      + +    + P  PS++P     P        ++K
Sbjct: 1089 VQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHP-------ESIK 1141

Query: 2038 SPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQ 2097
            +P    Q+ ++  +    P +       R  +  A  PG   +   + +P     P   +
Sbjct: 1142 APVHLPQRPEMKPVDVGRPVI-------RPPEQNAPPPGAPDKDKQKQEPKTPVAP--KK 1192

Query: 2098 QPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPN-----MASMNPQYR 2152
               ++N+ +  + V +    P   A    +   Q                  A    + +
Sbjct: 1193 DLKIKNMGSWASLVQKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEK 1252

Query: 2153 EMLRRQLL---------------------QQQQQQQQQQQQQQQQQQGSAGMAGGMAGHG 2191
            E LR++ +                     +Q+QQQQQ+Q+QQQQQQQ +A +A       
Sbjct: 1253 ERLRQERMRSREDEDALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQA 1312

Query: 2192 QFQQPQGPGGYPPAMQQQQR 2211
            Q  QPQ       +M  QQR
Sbjct: 1313 QSSQPQ-------SMLDQQR 1325



 Score = 72.8 bits (177), Expect = 4e-12
 Identities = 97/387 (25%), Positives = 143/387 (36%), Gaps = 55/387 (14%)

Query: 1814 QQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTS-APPGTPTQQPSTPQTPQPPAQPQ 1872
            ++Q +H     Q M++  A      VPQQ  P P    PP  P QQ   P  P PP+ PQ
Sbjct: 733  REQKKHHHHHHQQMQQAPAP-----VPQQPPPPPQQPPPPPPPQQQQQPPPPPPPPSMPQ 787

Query: 1873 PSPVSMSPAGFPSVARTQP------PTTV--STGKPTSQVPAPPPPAQPPPAAVEAARQI 1924
             +  +M  +  P +A   P      P +V    G  T  +   P P  PP          
Sbjct: 788  QAAPAMKSSPPPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHST 847

Query: 1925 EREAQQQQHLYRVNINNSMP--PGRTGMGTPGSQMAPVSLNVPRPNQVS-----GPVMPS 1977
                 Q   +    ++N++P  P R     P ++ A +     RP  VS      P++P 
Sbjct: 848  PPHLNQHAVVSPPALHNALPQQPSR-----PSNRAAALPPKPARPPAVSPALTQTPLLPQ 902

Query: 1978 MPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLK 2037
             P  Q  Q  L  ++P      P+ SMQ Q  +   ++  VQPP  + PS     ++   
Sbjct: 903  PPMAQPPQVLLEDEEPP---APPLTSMQMQLYL--QQLQKVQPPTPLLPS-----VKVQS 952

Query: 2038 SPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQ 2097
             P  P             P      ++Q+  +     P  QPQP  Q Q    P+P +H 
Sbjct: 953  QPPPPL------------PPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRP-VHL 999

Query: 2098 QPSLQNLNAMQAGVPR----PGVPPQQQ--AMGGLNPQGQALNIMNPGHNPNMASMNPQY 2151
            QP   + +  Q   P+    P  PP QQ        PQ    +  +P H+ +        
Sbjct: 1000 QPMQFSTHIQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHL 1059

Query: 2152 REMLRRQLLQQQQQQQQQQQQQQQQQQ 2178
            RE     ++   Q  Q Q    Q   Q
Sbjct: 1060 REAPSPLMIHSPQMSQFQSLTHQSPPQ 1086



 Score = 68.9 bits (167), Expect = 6e-11
 Identities = 104/472 (22%), Positives = 175/472 (37%), Gaps = 77/472 (16%)

Query: 1843 SLPSPTSAPPGTPTQQPSTPQTPQPP-AQPQ---------PSPVSMS---PAGFPSVART 1889
            +LP   + PP        TP  PQPP AQP          P+P   S         + + 
Sbjct: 879  ALPPKPARPPAVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKV 938

Query: 1890 QPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTG 1949
            QPPT +    P+ +V + PPP  PPP      +Q++++                PP    
Sbjct: 939  QPPTPLL---PSVKVQSQPPPPLPPPPHPSVQQQLQQQPPP-------------PPPPQP 982

Query: 1950 MGTPGSQMAPVSLNVP-RPNQVSGPVMPSMPP-GQWQQAPLPQQQPMPGLPRPVISMQAQ 2007
               P  Q  P    V  +P Q S  +    PP GQ    P P QQP P  P+P    Q  
Sbjct: 983  QPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQQPPP--PQPAKPQQVI 1040

Query: 2008 AAVAGPRMPSVQPPRS----ISPSALQ------DLLRTLKSPSSPQQQQQVLNILKSNPQ 2057
                 PR     P  +     +PS L          ++L   S PQQ     N+     +
Sbjct: 1041 QHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQ-----NVQPKKQE 1095

Query: 2058 LMAAFIKQRTAKYVANQPGMQPQPGLQSQP---GMQPQPGMH-----------QQPSLQN 2103
            L AA + Q     V  +  +   P ++S+P    ++P+P  H           Q+P ++ 
Sbjct: 1096 LRAASVVQPQPLVVVKEEKIH-SPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKP 1154

Query: 2104 LNA-------MQAGVPRPGVPPQ----QQAMGGLNPQGQALNIMNPGHNPNMASMNPQYR 2152
            ++         +   P PG P +    Q+    + P+ + L I N G   ++   +P   
Sbjct: 1155 VDVGRPVIRPPEQNAPPPGAPDKDKQKQEPKTPVAPK-KDLKIKNMGSWASLVQKHPTTP 1213

Query: 2153 EMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQF--QQPQGPGGYPPAMQQQQ 2210
                +      +Q ++  ++++++++     A       +   Q+         A++Q +
Sbjct: 1214 SSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALEQAR 1273

Query: 2211 RMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQ 2262
            R  +    +     Q   +  Q  Q     + A +TP  Q +  Q +L QQ+
Sbjct: 1274 RAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQR 1325



 Score = 66.2 bits (160), Expect = 4e-10
 Identities = 92/422 (21%), Positives = 141/422 (33%), Gaps = 51/422 (12%)

Query: 710  NHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSS---SG 766
            +H     +   VP     P + P PP              P Q Q  P    P S     
Sbjct: 742  HHQQMQQAPAPVPQQPPPPPQQPPPP------------PPPQQQQQPPPPPPPPSMPQQA 789

Query: 767  AMSVGMGQPP---AQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPAS 823
            A ++    PP    Q  V + Q+PG+   +P+         LP P +   P  P PP  S
Sbjct: 790  APAMKSSPPPFIATQVPVLEPQLPGSVF-DPIGHFTQPILHLPQPELP--PHLPQPPEHS 846

Query: 824  TAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAA 883
            T   +      +PP +    P  P++PS   ++    P   P   P+ TQT   P    A
Sbjct: 847  TPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPMA 906

Query: 884  AQAQVTPQPQTP-------------------VQPPSVATPQ-SSQQQPTPVHAQPPGTPL 923
               QV  + + P                   VQPP+   P    Q QP P    PP   +
Sbjct: 907  QPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSV 966

Query: 924  SQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEM 983
             Q         P P      +   Q P   V +  M+  T  +   P  G+    P    
Sbjct: 967  QQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPHPPPGQ 1026

Query: 984  MEEDLQGASQ---VKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPS 1040
                 Q A     ++        KS+P      +      +    + S   + +  + P 
Sbjct: 1027 QPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQ 1086

Query: 1041 QPRKKIFKPEELRQA--LMPTLEALYRQDPESLPF--RQPVDPQLL-GIPDYFDIVKNPM 1095
            Q  +   K +ELR A  + P    + +++    P    +P  P L    P + + +K P+
Sbjct: 1087 QNVQP--KKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRPEPPKHPESIKAPV 1144

Query: 1096 DL 1097
             L
Sbjct: 1145 HL 1146



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 133/515 (25%), Positives = 178/515 (34%), Gaps = 94/515 (18%)

Query: 1900 PTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAP 1959
            P  Q P PPPP QPPP             QQQQ           PP      +   Q AP
Sbjct: 752  PVPQQP-PPPPQQPPPPP---------PPQQQQQ----------PPPPPPPPSMPQQAAP 791

Query: 1960 VSLNVPRP---NQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMP 2016
               + P P    QV  PV+    PG          QP+  LP+P +             P
Sbjct: 792  AMKSSPPPFIATQV--PVLEPQLPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPP 849

Query: 2017 SVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPG 2076
             +     +SP AL + L   + PS P  +   L    + P  ++  + Q     +  QP 
Sbjct: 850  HLNQHAVVSPPALHNALP--QQPSRPSNRAAALPPKPARPPAVSPALTQTP---LLPQPP 904

Query: 2077 MQPQPGL---QSQPGMQPQPGMHQQPSLQNLNAMQAGVPR-PGVPPQQQAMGGLNPQGQA 2132
            M   P +     +P   P   M  Q  LQ L  +Q   P  P V  Q Q    L P    
Sbjct: 905  MAQPPQVLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPP---- 960

Query: 2133 LNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQ 2192
                 P H        P  ++ L++Q       Q Q   QQQ Q          M     
Sbjct: 961  -----PPH--------PSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTH 1007

Query: 2193 FQQPQGPGG----YPPAMQQ---------QQRMQQHLPLQGS-----SMGQMAAQMGQL- 2233
             QQP  P G    +PP  QQ         QQ +Q H   +       S G +      L 
Sbjct: 1008 IQQPPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHHSPRHHKSDPYSTGHLREAPSPLM 1067

Query: 2234 ---GQMGQ-PGLGADSTP--NIQQALQQ----RILQQQQM----KQQIGSPG-QPNPMSP 2278
                QM Q   L   S P  N+Q   Q+     ++Q Q +    +++I SP  +  P SP
Sbjct: 1068 IHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSP 1127

Query: 2279 QQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHV 2338
                 S +P+    P    A     Q     PV   RP  +PP  +  P   P       
Sbjct: 1128 -----SLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQKQ 1182

Query: 2339 SPQTG-SPHPGLAV-TMAS--SIDQGHLGNPEQSA 2369
             P+T  +P   L +  M S  S+ Q H   P  +A
Sbjct: 1183 EPKTPVAPKKDLKIKNMGSWASLVQKHPTTPSSTA 1217



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 31/76 (40%), Positives = 35/76 (46%), Gaps = 9/76 (11%)

Query: 1849 SAPPGTPT----QQPSTPQTPQPPAQPQPSPVSMSPAGFPSVART----QPPTTVSTGKP 1900
            +A PG  T     Q STP   Q P QP P PV  +P  FP+V        P  TV   +P
Sbjct: 188  TAKPGVSTVPNTTQASTPPQTQTP-QPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQP 246

Query: 1901 TSQVPAPPPPAQPPPA 1916
                P  PP  QPPPA
Sbjct: 247  LQTPPPVPPQPQPPPA 262



 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 57/247 (23%), Positives = 86/247 (34%), Gaps = 45/247 (18%)

Query: 745 MMAQAPAQSQFLPQNQFPSSSGAMSV----GMGQPPAQTGVSQGQVPGAALPNPLNMLGP 800
           +MA+A  +      N+ P+    + +    G G+   +TG ++  V  + +PN      P
Sbjct: 148 LMAEALEKLFLQKINELPTEETEIMIVQAKGRGRGRKETGTAKPGV--STVPNTTQASTP 205

Query: 801 QASQLPCP--PVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSG 858
             +Q P P  P  Q+  HP P           +    PP      P  P QP  P     
Sbjct: 206 PQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPP----- 260

Query: 859 QTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQP 918
             P P P  V      QS P + AA     TPQP    +        ++     P+H +P
Sbjct: 261 --PAPAPQPV------QSHPPIIAA-----TPQPVKTKKGVKRKADTTTPTTIDPIH-EP 306

Query: 919 PGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGE 978
           P  P       +  R  +   V       + P  DVP           D++  P   K  
Sbjct: 307 PSLPPEPKTTKLGQRRESSRPV-------KPPKKDVP-----------DSQQHPAPEKSS 348

Query: 979 PRSEMME 985
             SE ++
Sbjct: 349 KVSEQLK 355



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 27/78 (34%), Positives = 30/78 (38%), Gaps = 11/78 (14%)

Query: 1845 PSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTG------ 1898
            P  T  PP      P  P  PQPP  P P PV   P   P +A T  P     G      
Sbjct: 237  PVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPVQSHP---PIIAATPQPVKTKKGVKRKAD 293

Query: 1899 --KPTSQVPAPPPPAQPP 1914
               PT+  P   PP+ PP
Sbjct: 294  TTTPTTIDPIHEPPSLPP 311



 Score = 42.7 bits (99), Expect = 0.004
 Identities = 86/448 (19%), Positives = 155/448 (34%), Gaps = 133/448 (29%)

Query: 642  GNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPM 701
            G QP  P PG QP   P  QP +P        V +   S   +  +P S G+++   +P+
Sbjct: 1016 GQQPPHPPPGQQP---PPPQPAKPQQ------VIQHHHSPRHHKSDPYSTGHLREAPSPL 1066

Query: 702  GPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQF 761
                   M HS QM+   S                        +  Q+P Q    P+ Q 
Sbjct: 1067 -------MIHSPQMSQFQS------------------------LTHQSPPQQNVQPKKQ- 1094

Query: 762  PSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSP----LHP 817
                                   ++  A++  P  ++  +  ++  P +   P    L P
Sbjct: 1095 -----------------------ELRAASVVQPQPLVVVKEEKIHSPIIRSEPFSPSLRP 1131

Query: 818  TPP--PASTAAGMPSLQHTTPPGMTPPQP-AAPTQPSTPVSSSGQTPTPTPGSVPSATQT 874
             PP  P S  A          P   P +P   P     PV    +   P PG+     Q 
Sbjct: 1132 EPPKHPESIKA----------PVHLPQRPEMKPVDVGRPVIRPPEQNAPPPGAPDKDKQK 1181

Query: 875  QSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRV 934
            Q               +P+TPV P      ++                +   A+ +    
Sbjct: 1182 Q---------------EPKTPVAPKKDLKIKN----------------MGSWASLVQKHP 1210

Query: 935  PTPSSVASAETNS----QQPGPDVPVLEMKTETQAEDTEPDPGESKGE-PRSEMMEEDLQ 989
             TPSS A + ++S    ++   +    E   + QAE  E +    + E  RS   E+ L+
Sbjct: 1211 TTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDEDALE 1270

Query: 990  GASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKP 1049
             A +  EE    +++ +    ++++ +      +++ ++    A+     SQP+  + + 
Sbjct: 1271 QARRAHEEARRRQEQQQQQRQEQQQQQ------QQQAAAVAAAATPQAQSSQPQSMLDQQ 1324

Query: 1050 EEL----------RQALMPTLEALYRQD 1067
             EL          R+A+  T++  ++ D
Sbjct: 1325 RELARKREQERRRREAMAATIDMNFQSD 1352



 Score = 38.9 bits (89), Expect = 0.062
 Identities = 21/56 (37%), Positives = 33/56 (58%), Gaps = 3/56 (5%)

Query: 1516 KELEQEEEERKKEESTAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPS 1571
            K+ E++++E+KKE+     E  E  +     AK+   KKT KN SS S  +KK+P+
Sbjct: 537  KKKEKDKKEKKKEKHKRKEEVEENKK---SKAKEPPPKKTKKNNSSNSNVSKKEPA 589



 Score = 37.4 bits (85), Expect = 0.18
 Identities = 59/232 (25%), Positives = 86/232 (37%), Gaps = 40/232 (17%)

Query: 2163 QQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSS 2222
            ++Q++      QQ QQ  A +          Q P  P   PP    QQ+ Q   P    S
Sbjct: 733  REQKKHHHHHHQQMQQAPAPVPQ--------QPPPPPQQPPPPPPPQQQQQPPPPPPPPS 784

Query: 2223 MGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQ---QMKQQIGSPGQPNPMSPQ 2279
            M Q AA          P + +   P I  A Q  +L+ Q    +   IG   QP    PQ
Sbjct: 785  MPQQAA----------PAMKSSPPPFI--ATQVPVLEPQLPGSVFDPIGHFTQPILHLPQ 832

Query: 2280 QHMLSGQPQASHLPGQQIATSLSNQ--VRSPAPVQSPRPQSQPPHSSPSPRIQPQPS-PH 2336
              +    PQ    P +       NQ  V SP  + +  PQ     S+ +  + P+P+ P 
Sbjct: 833  PELPPHLPQ----PPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPP 888

Query: 2337 HVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSALSSELSL 2388
             VSP         A+T    + Q  +  P Q  +L     P+    S ++ L
Sbjct: 889  AVSP---------ALTQTPLLPQPPMAQPPQ-VLLEDEEPPAPPLTSMQMQL 930



 Score = 35.8 bits (81), Expect = 0.52
 Identities = 25/101 (24%), Positives = 36/101 (35%), Gaps = 8/101 (7%)

Query: 1839 VPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQ--------PSPVSMSPAGFPSVARTQ 1890
            VP Q  P P  AP    +  P    TPQP    +         +P ++ P   P     +
Sbjct: 253  VPPQPQPPPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPE 312

Query: 1891 PPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQ 1931
            P TT    +  S  P  PP    P +    A +   +  +Q
Sbjct: 313  PKTTKLGQRRESSRPVKPPKKDVPDSQQHPAPEKSSKVSEQ 353



 Score = 33.1 bits (74), Expect = 3.4
 Identities = 31/106 (29%), Positives = 40/106 (37%), Gaps = 16/106 (15%)

Query: 2242 GADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSL 2301
            G  + PN  QA             Q  +P QPNP   Q    +  P  +  P   + T +
Sbjct: 192  GVSTVPNTTQA---------STPPQTQTP-QPNPPPVQA---TPHPFPAVTPDLIVQTPV 238

Query: 2302 SNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHP 2347
               V  P P+Q+P P   PP   P P   PQP   H      +P P
Sbjct: 239  MTVV-PPQPLQTPPP--VPPQPQPPPAPAPQPVQSHPPIIAATPQP 281



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 26/130 (20%), Positives = 46/130 (35%), Gaps = 9/130 (6%)

Query: 916  AQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGES 975
            A+ P  P     A     VP P+ V +  ++S               +   D+  D  E 
Sbjct: 455  AKMPDEPEEPVVAVSSPAVPPPTKVVAPPSSSDSSSDS---------SSDSDSSTDDSEE 505

Query: 976  KGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQ 1035
            +   R   ++E L+   +        +Q     +  +KK + K + K +EE   N  +  
Sbjct: 506  ERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKHKRKEEVEENKKSKA 565

Query: 1036 STSPSQPRKK 1045
               P +  KK
Sbjct: 566  KEPPPKKTKK 575


>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
          Length = 748

 Score = 95.1 bits (235), Expect = 7e-19
 Identities = 121/415 (29%), Positives = 162/415 (39%), Gaps = 62/415 (14%)

Query: 1993 PMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNIL 2052
            P  G  + +  M +  A+  P   S QPP   S  A   +   + S ++PQ Q Q+  + 
Sbjct: 102  PPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSM--AVVSTATPQTQLQLQQVA 159

Query: 2053 KSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVP 2112
                Q    F +Q+ A     Q   Q Q     Q  MQ Q               QA   
Sbjct: 160  LQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQ--------------FQA--- 202

Query: 2113 RPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQ 2172
               V  QQQ +     Q Q L  +   H+ N   +  Q +++ R   LQ QQQQQQQQQQ
Sbjct: 203  ---VVQQQQQLQQQQQQQQHLIKL---HHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQ 256

Query: 2173 QQQQQQGSAGMAGGMAGHGQFQQPQGP--GGYPPAMQQQQRMQQHLPLQGSSMGQMAA-Q 2229
            QQQQQQ  A  A         QQPQ P     P  +QQ    Q H P        +A  Q
Sbjct: 257  QQQQQQ--ALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQ 314

Query: 2230 MGQLGQMGQ-----------PGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSP 2278
              QL    Q           PG    + P ++      ++QQ         P QP     
Sbjct: 315  PSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQ--------PPVQPQVQQQ 366

Query: 2279 QQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPR-PQSQPPHSSPSPRIQP-QPSPH 2336
            Q  + + Q      PG Q++ S    + SP+P Q  + PQS PP   PSP  QP QPS  
Sbjct: 367  QTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSP--QPGQPSSQ 424

Query: 2337 HVSPQTGSPHPGLAVTMASSIDQGHLGNPEQS---AMLPQ-LNTPSRSALSSELS 2387
              S  +  P P  +  + S   Q     P QS   A  PQ  + PS   L++ ++
Sbjct: 425  PNSNVSSGPAPSPSSFLPSPSPQ-----PSQSPVTARTPQNFSVPSPGPLNTPVN 474



 Score = 78.6 bits (192), Expect = 7e-14
 Identities = 112/415 (26%), Positives = 150/415 (36%), Gaps = 51/415 (12%)

Query: 1945 PGRT--GMGTPGSQMAPVSLNVPRPNQVSGPVMPSM---------PPGQWQQAPLPQQQP 1993
            PG++  GMG+ G+   P+SL+   P   SG    SM            Q QQ  L QQQ 
Sbjct: 106  PGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQ- 164

Query: 1994 MPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTL--KSPSSPQQQQQVLNI 2051
                 +     Q QAA+   +    Q       SA+Q   + +  +     QQQQQ  ++
Sbjct: 165  ----QQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHL 220

Query: 2052 LKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGV 2111
            +K + Q      +Q+       Q  +Q Q   Q Q   Q Q  +  QP +Q     Q  +
Sbjct: 221  IKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQ-----QPPM 275

Query: 2112 PRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQ 2171
             +P  PP Q       PQ          H P      P               Q Q  Q 
Sbjct: 276  QQPQPPPSQAL-----PQQLQQMHHTQHHQPPPQPQQPPV------------AQNQPSQL 318

Query: 2172 QQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMG 2231
              Q Q Q     A  + G   + QP       P + QQ  +Q  +  Q     Q A Q  
Sbjct: 319  PPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQ-----QTAVQTA 373

Query: 2232 QLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASH 2291
            Q  QM  PG+   S  ++         QQ Q  Q +  P QP   SPQ    S QP ++ 
Sbjct: 374  QAAQMVAPGVQV-SQSSLPMLSSPSPGQQVQTPQSMPPPPQP---SPQPGQPSSQPNSNV 429

Query: 2292 LPGQQIATSLSNQVRSPAPVQSPRPQSQPPH-SSPSPRIQPQP-SPHHVSPQTGS 2344
              G   + S      SP P QSP     P + S PSP     P +P  V    GS
Sbjct: 430  SSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGS 484



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 70/240 (29%), Positives = 94/240 (39%), Gaps = 33/240 (13%)

Query: 1811 KLRQQQIQHRLQQAQLMRRRMATMNTRNVP-QQSLPSPTSAPPGTPTQQPSTPQTPQPPA 1869
            +L+QQQ Q + QQ Q  +   A    +  P QQ  P P+ A P    QQ    Q  QPP 
Sbjct: 245  QLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALP-QQLQQMHHTQHHQPPP 303

Query: 1870 QPQPSPVSMS-PAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREA 1928
            QPQ  PV+ + P+  P  ++TQP  + +   P   +   PP        V     ++ + 
Sbjct: 304  QPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQV 363

Query: 1929 QQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPL 1988
            QQQQ   +             M  PG Q++  SL          P++ S  PG  QQ   
Sbjct: 364  QQQQTAVQT-------AQAAQMVAPGVQVSQSSL----------PMLSSPSPG--QQVQT 404

Query: 1989 PQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQV 2048
            PQ  P P  P P            P  PS QP  ++S          L SPS    Q  V
Sbjct: 405  PQSMPPPPQPSP-----------QPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPV 453



 Score = 62.4 bits (150), Expect = 5e-09
 Identities = 76/298 (25%), Positives = 117/298 (39%), Gaps = 66/298 (22%)

Query: 622 KIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQ 681
           ++Q++ +++++ +  +Q  L  QP +  P       P  QP  PP+  L   + +M  +Q
Sbjct: 245 QLQQQQQQQQQQQQQQQQALQAQPPIQQP-------PMQQPQPPPSQALPQQLQQMHHTQ 297

Query: 682 GMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAH 741
                      + Q P  P  P  A                     PS++P       + 
Sbjct: 298 -----------HHQPPPQPQQPPVAQN------------------QPSQLPPQ-----SQ 323

Query: 742 TNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQ 801
           T  +++QA A    +   Q P       + + QPP Q  V Q Q           +   Q
Sbjct: 324 TQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTA---------VQTAQ 374

Query: 802 ASQLPCPPVTQS----PLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAP-TQPSTPVSS 856
           A+Q+  P V  S    P+  +P P      + + Q   PP    PQP  P +QP++ VSS
Sbjct: 375 AAQMVAPGVQVSQSSLPMLSSPSPGQQ---VQTPQSMPPPPQPSPQPGQPSSQPNSNVSS 431

Query: 857 SGQTPTPTPGS-VPS-ATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQ 909
               P P+P S +PS + Q   +P      Q    P P    TPV P SV +P  S Q
Sbjct: 432 G---PAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQ 486



 Score = 60.8 bits (146), Expect = 2e-08
 Identities = 94/412 (22%), Positives = 143/412 (34%), Gaps = 43/412 (10%)

Query: 595 AKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRL-HKQGILGNQPALPAPGAQ 653
           +K +E  ++  A +RDEY  L+A  I   +    +K ++ +      L +    PA GA 
Sbjct: 38  SKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAA 97

Query: 654 PPVIPQAQPVRPPNG---------PLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPR 704
              +P   P +   G         P+SL       + GM + + M++ +   PQ  +  +
Sbjct: 98  GIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGM-APHSMAVVSTATPQTQLQLQ 156

Query: 705 AASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPA---QSQFLPQNQF 761
             + +    Q          A+   +  Q      A  + M  Q  A   Q Q L Q Q 
Sbjct: 157 QVA-LQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQ 215

Query: 762 PSS-------SGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSP 814
                          +   Q   Q  ++Q Q+              Q +    PP+ Q P
Sbjct: 216 QQQHLIKLHHQNQQQIQQQQQQLQR-IAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPP 274

Query: 815 L-HPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQ 873
           +  P PPP+          H T     PPQP  P     PV+ +       P  +P  +Q
Sbjct: 275 MQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQP-----PVAQN------QPSQLPPQSQ 323

Query: 874 TQSTPTVQAAAQAQVTPQPQTPVQPP--SVATPQSSQQQPTPVHAQPPGTPLSQAAASID 931
           TQ  P V   +QAQ  P      QPP   V  P   QQ P     Q   T + Q A +  
Sbjct: 324 TQ--PLV---SQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAV-QTAQAAQ 377

Query: 932 NRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEM 983
              P      S+      P P   V   ++        P PG+   +P S +
Sbjct: 378 MVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNV 429



 Score = 55.1 bits (131), Expect = 8e-07
 Identities = 83/356 (23%), Positives = 132/356 (37%), Gaps = 31/356 (8%)

Query: 714  QMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPS-SSGAMSVGM 772
            Q  ++ + P +   P + PQPP                  Q  PQ Q P  +    S   
Sbjct: 260  QQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLP 319

Query: 773  GQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSP-LHPTPPPASTAAGMPSL 831
             Q   Q  VSQ Q    ALP  +    P    +  P V Q P + P      TA      
Sbjct: 320  PQSQTQPLVSQAQ----ALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQA 375

Query: 832  QHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQ 891
                 PG+        +Q S P+ SS     P+PG      Q+   P   +    Q + Q
Sbjct: 376  AQMVAPGVQV------SQSSLPMLSS-----PSPGQQVQTPQSMPPPPQPSPQPGQPSSQ 424

Query: 892  PQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVP-----TPSSVASAETN 946
            P + V      +P S    P+P  +Q P T  +    S+ +  P      PSSV S   +
Sbjct: 425  PNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGS 484

Query: 947  SQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSE 1006
            SQ    +   L+ K +  ++  EP         ++E  ++DL   S++K   DI    ++
Sbjct: 485  SQ--AEEQQYLD-KLKQLSKYIEPLRRMINKIDKNEDRKKDL---SKMKSLLDIL---TD 535

Query: 1007 PMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEA 1062
            P +    K   K E+  E+  +     +    P  P K+ +  + L  A++  + +
Sbjct: 536  PSKRCPLKTLQKCEIALEKLKNDMAVPTPPPPPVPPTKQQYLCQPLLDAVLANIRS 591



 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 40/108 (37%), Positives = 52/108 (48%), Gaps = 16/108 (14%)

Query: 1814 QQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQP 1873
            Q Q+Q +    Q  +          V Q SLP  +S  PG   QQ  TPQ+  PP QP P
Sbjct: 360  QPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPG---QQVQTPQSMPPPPQPSP 416

Query: 1874 SPVSMSPAGFPSVARTQPPTTVSTG---KPTSQVPAP-PPPAQPPPAA 1917
             P      G PS   +QP + VS+G    P+S +P+P P P+Q P  A
Sbjct: 417  QP------GQPS---SQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTA 455



 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 71/287 (24%), Positives = 104/287 (36%), Gaps = 66/287 (22%)

Query: 1916 AAVEAARQIEREAQQQQHLYRVNINN-----------------------------SMPPG 1946
            A V+  +Q++++ QQQQHL +++  N                                  
Sbjct: 202  AVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQ 261

Query: 1947 RTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSM-------PPGQWQQAPLPQQQPMPGLP- 1998
            +     P  Q  P+    P P+Q     +  M       PP Q QQ P+ Q QP    P 
Sbjct: 262  QALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQ 321

Query: 1999 ---RPVISMQAQAAVAGPRMPSVQPPRSI--SPSALQDLLRTLKSPSSPQQQQQVLNILK 2053
               +P++S QAQA     +M   QPP     +P  +Q      + P  PQ QQQ   +  
Sbjct: 322  SQTQPLVS-QAQALPG--QMLYTQPPLKFVRAPMVVQ------QPPVQPQVQQQQTAVQT 372

Query: 2054 SNPQLMAA---FIKQRTAKYVAN-QPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLN---- 2105
            +    M A    + Q +   +++  PG Q Q      P  QP P   Q  S  N N    
Sbjct: 373  AQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSG 432

Query: 2106 ---AMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNP 2149
               +  + +P P   P Q  +    PQ    N   P   P    +NP
Sbjct: 433  PAPSPSSFLPSPSPQPSQSPVTARTPQ----NFSVPSPGPLNTPVNP 475



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 39/142 (27%), Positives = 63/142 (44%), Gaps = 22/142 (15%)

Query: 1808 IKHKLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSP---------------TSAPP 1852
            ++ +++QQQ   +  QA  M      ++  ++P  S PSP                S  P
Sbjct: 359  VQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQP 418

Query: 1853 GTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQ 1912
            G P+ QP++       + P PSP S  P+  PS   +Q P T  T +  S VP+P P   
Sbjct: 419  GQPSSQPNS----NVSSGPAPSPSSFLPS--PSPQPSQSPVTARTPQNFS-VPSPGPLNT 471

Query: 1913 PPPAAVEAARQIEREAQQQQHL 1934
            P   +   +     +A++QQ+L
Sbjct: 472  PVNPSSVMSPAGSSQAEEQQYL 493



 Score = 38.1 bits (87), Expect = 0.11
 Identities = 56/271 (20%), Positives = 82/271 (30%), Gaps = 22/271 (8%)

Query: 252 GHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASKQSMVNSLPTFP 311
           G AG+     G    +G  G+    GQP S +G  P G +G+ P   S   +  + P   
Sbjct: 95  GAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPH--SMAVVSTATPQTQ 152

Query: 312 TDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVLLLHAHKCQRRE 371
             ++  ++       Q Q        Q          + ++   QQ    +   + Q ++
Sbjct: 153 LQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQ 212

Query: 372 QANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQAILGSPASGIQNTIGSVGTGQQNATS 431
           Q   +     L H        N     Q  +  Q I        Q         QQ A  
Sbjct: 213 QQQQQQHLIKLHH-------QNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQ 265

Query: 432 LSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPM 491
              P    P    +   +  LP   Q     Q   P  QP QP   Q         N P 
Sbjct: 266 AQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQ---------NQPS 316

Query: 492 NIPAGGITTDQQPPNLISESALPTSLGATNP 522
            +P       Q  P +    ALP  +  T P
Sbjct: 317 QLP----PQSQTQPLVSQAQALPGQMLYTQP 343


>gi|110347429 mediator complex subunit 12 [Homo sapiens]
          Length = 2177

 Score = 94.7 bits (234), Expect = 9e-19
 Identities = 119/481 (24%), Positives = 177/481 (36%), Gaps = 72/481 (14%)

Query: 1870 QPQPSPVSMSPAGFPSVARTQP-PTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREA 1928
            +P+P    + P   P      P PT +   K   + P    P   PP+  E  ++  +  
Sbjct: 1731 RPRPRAYYLEPLPLPPEDEEPPAPTLLEPEKKAPEPPKTDKPGAAPPSTEERKKKSTKGK 1790

Query: 1929 QQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQW-QQAP 1987
            ++ Q   +   +  M PGR+G    G  + P  L+ P P  ++         G + Q  P
Sbjct: 1791 KRSQPATKTE-DYGMGPGRSG--PYGVTVPPDLLHHPNPGSITHLNYRQGSIGLYTQNQP 1847

Query: 1988 LPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPR-----SISPSALQDLLRTLKSPSSP 2042
            LP   P     RPV  +  Q     P  P V P        + PS+ +  +   + P+ P
Sbjct: 1848 LPAGGPRVDPYRPV-RLPMQKLPTRPTYPGVLPTTMTGVMGLEPSSYKTSVYRQQQPAVP 1906

Query: 2043 QQQQQVLNILKSNPQLMAAFIKQRTAKY---VANQPGMQP---QPGLQSQPG----MQPQ 2092
            Q Q+    + +S   L  + + Q T      +    G  P     GLQ   G    M P 
Sbjct: 1907 QGQRLRQQLQQSQGMLGQSSVHQMTPSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVP- 1965

Query: 2093 PGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQG----------QALNIMNPGHNP 2142
            P    QP      +    +  P    QQ+  G ++ Q           Q  +       P
Sbjct: 1966 PSYSSQPYQSTHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTP 2025

Query: 2143 NMASMNPQYREMLRR-----QLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQ 2197
             +++M P   + ++       +L +QQQQQQQQQQQQQQQQ                   
Sbjct: 2026 MISTMTPMSAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQ------------------- 2066

Query: 2198 GPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRI 2257
                     QQQQ+ QQ   ++     Q+  Q  Q  Q  Q           QQ  QQ+ 
Sbjct: 2067 --------QQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQ-----QQQQQQQQQQQQQQ 2113

Query: 2258 LQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQ 2317
             Q QQ +QQ  +P QP P S  Q    G  Q      QQ   +L  Q++       P+P 
Sbjct: 2114 QQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQ---QQQTAALVRQLQQQLSNTQPQPS 2170

Query: 2318 S 2318
            +
Sbjct: 2171 T 2171



 Score = 37.0 bits (84), Expect = 0.23
 Identities = 83/397 (20%), Positives = 121/397 (30%), Gaps = 70/397 (17%)

Query: 636  HKQGILG----NQPALPAPGAQ-----PPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSF 686
            ++QG +G    NQP LPA G +     P  +P  +    P  P  LP     V     S 
Sbjct: 1834 YRQGSIGLYTQNQP-LPAGGPRVDPYRPVRLPMQKLPTRPTYPGVLPTTMTGVMGLEPSS 1892

Query: 687  NPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMM 746
               S+   Q P  P G R    +  S  M    SV  M                      
Sbjct: 1893 YKTSVYRQQQPAVPQGQRLRQQLQQSQGMLGQSSVHQMT--------------------- 1931

Query: 747  AQAPAQSQFLPQNQFPSSSGAMSVGMGQPP--AQTGVSQGQVPGAALPNPLNMLGPQASQ 804
                           PSSS  +    G  P  +  G+ Q   P   +  P      Q  Q
Sbjct: 1932 ---------------PSSSYGLQTSQGYTPYVSHVGLQQHTGPAGTMVPP--SYSSQPYQ 1974

Query: 805  LPCPPVTQSPLHPTPPPASTAAGMPSLQHTT-PPGMTPPQP-AAPTQPSTPVSSSGQTPT 862
               P    + + PT       +G    Q  T   G+T  Q  +  T   TP+ S+  TP 
Sbjct: 1975 STHPSTNPTLVDPTRHLQQRPSGYVHQQAPTYGHGLTSTQRFSHQTLQQTPMIST-MTPM 2033

Query: 863  PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP 922
               G       T   P  Q   Q Q   Q Q   Q       Q  QQQ   +  Q     
Sbjct: 2034 SAQGVQAGVRSTAILPEQQQQQQQQQQQQQQQQQQ------QQQQQQQQYHIRQQQQQQI 2087

Query: 923  LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE 982
            L Q       +          +   QQ        + + + QA   +P P     + + +
Sbjct: 2088 LRQQQQQQQQQQQQQQQQQQQQQQQQQQH------QQQQQQQAAPPQPQP-----QSQPQ 2136

Query: 983  MMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKV 1019
               + LQ   Q ++   +  Q  + +   + +P   +
Sbjct: 2137 FQRQGLQQTQQQQQTAALVRQLQQQLSNTQPQPSTNI 2173



 Score = 32.0 bits (71), Expect = 7.5
 Identities = 20/61 (32%), Positives = 27/61 (44%), Gaps = 12/61 (19%)

Query: 1812 LRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQP 1871
            LRQQQ Q + QQ Q  +++      +   QQ              QQ + P  PQP +QP
Sbjct: 2088 LRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQ------------QQQQAAPPQPQPQSQP 2135

Query: 1872 Q 1872
            Q
Sbjct: 2136 Q 2136


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 92.8 bits (229), Expect = 4e-18
 Identities = 126/500 (25%), Positives = 176/500 (35%), Gaps = 117/500 (23%)

Query: 1871 PQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQ--------PPPAAVEAAR 1922
            P  +P+S+S +G      T+PPTT   G     +P+ PPPA         PPP A+    
Sbjct: 255  PPTTPISVSSSGASGAPPTKPPTTPVGG---GNLPSAPPPANFPHVTPNLPPPPALRP-- 309

Query: 1923 QIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQ 1982
                          +N  ++ PPG      PG        ++P P+ + G  M  +PPG 
Sbjct: 310  --------------LNNASASPPGLGAQPLPG--------HLPSPHAM-GQGMGGLPPG- 345

Query: 1983 WQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSP 2042
                  P++ P    P P     A ++   P M       S S +A      +  S +SP
Sbjct: 346  ------PEKGPTLA-PSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASP 398

Query: 2043 QQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQP--GMQPQPGMHQQPS 2100
                Q L      P    +F    T+  V+NQP    QP L SQ      P P       
Sbjct: 399  FPASQAL------PSYPHSF-PPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRL 451

Query: 2101 LQNLNAMQAGVPRPG-VPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQL 2159
            L N NA       PG  PP   A    +P       ++  H+ +                
Sbjct: 452  LANSNA------HPGPFPPSTGAQSTAHPP------VSTHHHHH---------------- 483

Query: 2160 LQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQ 2219
             QQQQQQQQQQQQQQQQQQ   G +G          P  PG +P  ++       H    
Sbjct: 484  -QQQQQQQQQQQQQQQQQQQHHGNSG----------PPPPGAFPHPLEGGSSHHAHPYAM 532

Query: 2220 GSSMGQMAA------------QMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQI 2267
              S+G +                    Q G  G    S+ N   +  Q            
Sbjct: 533  SPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQ 592

Query: 2268 GSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHS--SP 2325
            G  G P P  P   + +            ++T ++    SPA  ++  P   PP+   +P
Sbjct: 593  GPQGAPYPFPPVPTVTTS--------SATLSTVIATVASSPAGYKTASPPGPPPYGKRAP 644

Query: 2326 SPRIQPQPSPHHVSPQTGSP 2345
            SP      +P    P  GSP
Sbjct: 645  SPGAYKTATPPGYKP--GSP 662



 Score = 63.2 bits (152), Expect = 3e-09
 Identities = 147/682 (21%), Positives = 222/682 (32%), Gaps = 119/682 (17%)

Query: 408  LGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQP-QV 466
            +G    G  +++G    G+Q+      P P  P S+  + A+ G P    P T +    +
Sbjct: 233  MGPKGGGAASSVGGPNGGKQH------PPPTTPISVSSSGAS-GAPPTKPPTTPVGGGNL 285

Query: 467  PGQQPAQPQTHQQMRTLNPLGNNPMNIPAG---GITTDQQPPNLISESALPTSLGATNPL 523
            P   P     H       P    P+N  +    G+     P +L S  A+   +G   P 
Sbjct: 286  PSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPG 345

Query: 524  MNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAAL 583
               G       TL+  P + PP+S+             +R              P  ++ 
Sbjct: 346  PEKGP------TLAPSPHSLPPASSSAP-------APPMRF-------------PYSSSS 379

Query: 584  KDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKI-YKIQKELEEKRRSRLHKQGILG 642
                  +  + +       + ++ +   Y H         +  +  +  +  L  Q +  
Sbjct: 380  SSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWS 439

Query: 643  NQPALPAP--------GAQP-PVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGN 693
              P  P P         A P P  P        + P+S   +  Q  Q            
Sbjct: 440  QGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQ 499

Query: 694  VQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSR---MPQPPNMMGAHTNNMMAQAP 750
             Q      GP       H ++  S       A+SPS     P PP    AH     +Q  
Sbjct: 500  QQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGP--AHLPPPHSQV- 556

Query: 751  AQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPV 810
            + SQ  P     SSS   S         +  SQG  P  + P+P    GPQ +  P PPV
Sbjct: 557  SYSQAGPNGPPVSSSSNSS---------SSTSQGSYP-CSHPSPSQ--GPQGAPYPFPPV 604

Query: 811  -------------------------TQSPLHPTPPPASTAAGMPSLQHT-TPPGMTPPQP 844
                                     T SP  P PPP    A  P    T TPPG  P  P
Sbjct: 605  PTVTTSSATLSTVIATVASSPAGYKTASP--PGPPPYGKRAPSPGAYKTATPPGYKPGSP 662

Query: 845  AAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATP 904
             +  +  TP    G +P   PG+    + T             V P P  P      A P
Sbjct: 663  PS-FRTGTPPGYRGTSPPAGPGTFKPGSPT-------------VGPGPLPP------AGP 702

Query: 905  QSSQQQPTPVHAQPPGTPLS--QAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTE 962
                  P P  A   G PLS  Q          TP S      +   P   V V    ++
Sbjct: 703  SGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQ 762

Query: 963  TQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAE---QKSEPMEVDEKKPEVKV 1019
            +   +   D G +    RS++    L+G+   K+  D+ E   +++E    +EK+ E + 
Sbjct: 763  SARFNKHLDRGFNSC-ARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKERERER 821

Query: 1020 EVKEEEESSSNGTASQSTSPSQ 1041
            E ++E E        +S   +Q
Sbjct: 822  EREKEREREKERELERSVKLAQ 843



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 66/305 (21%), Positives = 100/305 (32%), Gaps = 40/305 (13%)

Query: 769  SVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLH-PTPPPASTAAG 827
            S G+ Q PA+        P +  P       P+AS  P P VT +  H P  PP S    
Sbjct: 148  SSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSR--- 204

Query: 828  MPSLQHTTPPGMTPPQP-----------AAPTQPSTPVSSSGQTPTPTPGSVPSATQTQS 876
                    PPG  PP P           + P        ++     P  G       T  
Sbjct: 205  ----MFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPI 260

Query: 877  TPTVQAAAQAQVTPQPQTPVQPPSV--ATPQSSQQQPTPVHAQPPG-TPLSQAAAS---- 929
            + +   A+ A  T  P TPV   ++  A P ++    TP    PP   PL+ A+AS    
Sbjct: 261  SVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGL 320

Query: 930  ----IDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEM-- 983
                +   +P+P ++         PGP+      K  T A      P  S   P   M  
Sbjct: 321  GAQPLPGHLPSPHAMGQG-MGGLPPGPE------KGPTLAPSPHSLPPASSSAPAPPMRF 373

Query: 984  -MEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP 1042
                    ++     +  +   + P    +  P            S +    + T PS P
Sbjct: 374  PYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLP 433

Query: 1043 RKKIF 1047
             + ++
Sbjct: 434  SQAVW 438



 Score = 45.1 bits (105), Expect = 9e-04
 Identities = 43/144 (29%), Positives = 57/144 (39%), Gaps = 26/144 (18%)

Query: 1832 ATMNTRNVPQQSLPS--PTSAPPGTP-----TQQPSTPQTPQPPAQPQPSPVSMSPAGFP 1884
            AT++T      S P+   T++PPG P        P   +T  PP     SP S      P
Sbjct: 612  ATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPP 671

Query: 1885 SVARTQPPTTVSTGKPTSQV--PAPPPPA--------QPPPAAVE-----AARQIEREAQ 1929
                T PP    T KP S    P P PPA         PPPAA       +A QI++E  
Sbjct: 672  GYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPA 731

Query: 1930 QQQHLYRVNINNSMPPGRTGMGTP 1953
            ++         + +PP R+    P
Sbjct: 732  EEYE----TPESPVPPARSPSPPP 751



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 32/97 (32%), Positives = 44/97 (45%), Gaps = 8/97 (8%)

Query: 1848 TSAPPGTPTQQPSTPQT---PQPPAQPQ--PS--PVSMSPAGFPSVARTQPPTTVSTGKP 1900
            TS P G  T +P +P     P PPA P   PS  P   +PA  P ++ TQ     +    
Sbjct: 676  TSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYE 735

Query: 1901 TSQVPAPPPPA-QPPPAAVEAARQIEREAQQQQHLYR 1936
            T + P PP  +  PPP  V+      + A+  +HL R
Sbjct: 736  TPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDR 772



 Score = 41.6 bits (96), Expect = 0.010
 Identities = 66/302 (21%), Positives = 94/302 (31%), Gaps = 58/302 (19%)

Query: 704 RAASPMNHSVQM--NSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQF 761
           R+ SP  +S     N   S  G++  P+R   PP +          Q P  +   P+  F
Sbjct: 129 RSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSP-----QPPDSTPRQPEASF 183

Query: 762 PSSSGAMSVGMGQP--PAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPV--------- 810
                    G   P  P  + + Q   PGA  P+P    G     L  PP+         
Sbjct: 184 EPHPSVTPTGYHAPMEPPTSRMFQAP-PGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAAS 242

Query: 811 -----TQSPLHPTPP-PASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPT 864
                     HP P  P S ++   S       G  P +P     P+TPV        P 
Sbjct: 243 SVGGPNGGKQHPPPTTPISVSSSGAS-------GAPPTKP-----PTTPVGGGNLPSAPP 290

Query: 865 PGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQ------- 917
           P + P  T     P         + P       PP +         P+P HA        
Sbjct: 291 PANFPHVTPNLPPPPA-------LRPLNNASASPPGLGAQPLPGHLPSP-HAMGQGMGGL 342

Query: 918 PPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKG 977
           PPG       A      P+P S+  A +++  P    P     + + A  +      S  
Sbjct: 343 PPGPEKGPTLA------PSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSA 396

Query: 978 EP 979
            P
Sbjct: 397 SP 398



 Score = 41.2 bits (95), Expect = 0.012
 Identities = 66/279 (23%), Positives = 87/279 (31%), Gaps = 72/279 (25%)

Query: 1810 HKLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSA------------------- 1850
            H  +QQQ Q + QQ Q  +++    N+   P  + P P                      
Sbjct: 481  HHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLR 540

Query: 1851 --PPGTPTQQPSTPQTPQPPAQPQPSPVSMS------------PAGFPSVAR-------- 1888
              PPG     P   Q     A P   PVS S            P   PS ++        
Sbjct: 541  PYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYP 600

Query: 1889 -------TQPPTTVST----------GKPTSQVPAPPPPAQ--PPPAAVEAARQIEREAQ 1929
                   T    T+ST          G  T+  P PPP  +  P P A + A     +  
Sbjct: 601  FPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPG 660

Query: 1930 QQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLP 1989
                    +     PPG  G   P     P +     P    GP+ P+ P G     P P
Sbjct: 661  SPP-----SFRTGTPPGYRGTSPPA---GPGTFKPGSPTVGPGPLPPAGPSG-LPSLPPP 711

Query: 1990 QQQPMPGLPRPVISMQAQAA--VAGPRMPSVQPPRSISP 2026
               P  G P     ++ + A     P  P V P RS SP
Sbjct: 712  PAAPASGPPLSATQIKQEPAEEYETPESP-VPPARSPSP 749



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 74/314 (23%), Positives = 104/314 (33%), Gaps = 52/314 (16%)

Query: 1832 ATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQ------TPQPPAQPQPSPVSMSPAGFPS 1885
            A  ++ +    S  SP  A    P+   S P       + QPP   QPS  S       +
Sbjct: 383  AAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQ------A 436

Query: 1886 VARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAA--------RQIEREAQQQQHLYRV 1937
            V    PP     G+  +   A P P  P   A   A           +++ QQQQ   + 
Sbjct: 437  VWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQ 496

Query: 1938 NINNSMPPGRTGMGTPGSQMAPV---SLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPM 1994
                    G +G   PG+   P+   S +   P  +S P + S+ P      P P   P 
Sbjct: 497  QQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMS-PSLGSLRP----YPPGPAHLPP 551

Query: 1995 PGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQ------- 2047
            P         Q   + AGP  P V    + S S  Q       S  SP Q  Q       
Sbjct: 552  P-------HSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPC--SHPSPSQGPQGAPYPFP 602

Query: 2048 -VLNILKSNPQL--MAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNL 2104
             V  +  S+  L  + A +    A Y    P   P  G ++     P PG ++  +    
Sbjct: 603  PVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRA-----PSPGAYKTATPPGY 657

Query: 2105 NAMQAGVPRPGVPP 2118
                    R G PP
Sbjct: 658  KPGSPPSFRTGTPP 671



 Score = 32.0 bits (71), Expect = 7.5
 Identities = 68/292 (23%), Positives = 92/292 (31%), Gaps = 47/292 (16%)

Query: 2086 QPGMQPQPGMHQQPSLQNLNAMQAGV---------PRPGVPPQQQAMGGLNPQGQALNIM 2136
            Q      P ++   S++N +   +G+         P P  PP  Q       Q +A    
Sbjct: 126  QDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEP 185

Query: 2137 NPGHNPN--MASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQ 2194
            +P   P    A M P    M        Q          Q    G+ G+  G        
Sbjct: 186  HPSVTPTGYHAPMEPPTSRMF-------QAPPGAPPPHPQLYPGGTGGVLSG-------- 230

Query: 2195 QPQGP--GGYPPAMQQQQRMQQH----LPLQGSSMGQMAAQM----------GQLGQMGQ 2238
             P GP  GG   ++      +QH     P+  SS G   A            G L     
Sbjct: 231  PPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPP 290

Query: 2239 PGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMS-PQQHMLSGQPQASHLPGQQI 2297
            P      TPN+      R L         G   QP P   P  H + GQ      PG + 
Sbjct: 291  PANFPHVTPNLPPPPALRPLNNASASPP-GLGAQPLPGHLPSPHAM-GQGMGGLPPGPEK 348

Query: 2298 ATSLSNQVRS--PAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHP 2347
              +L+    S  PA   +P P  + P+SS S       S    S  + SP P
Sbjct: 349  GPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFP 400


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 92.8 bits (229), Expect = 4e-18
 Identities = 126/500 (25%), Positives = 176/500 (35%), Gaps = 117/500 (23%)

Query: 1871 PQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQ--------PPPAAVEAAR 1922
            P  +P+S+S +G      T+PPTT   G     +P+ PPPA         PPP A+    
Sbjct: 255  PPTTPISVSSSGASGAPPTKPPTTPVGG---GNLPSAPPPANFPHVTPNLPPPPALRP-- 309

Query: 1923 QIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQ 1982
                          +N  ++ PPG      PG        ++P P+ + G  M  +PPG 
Sbjct: 310  --------------LNNASASPPGLGAQPLPG--------HLPSPHAM-GQGMGGLPPG- 345

Query: 1983 WQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSP 2042
                  P++ P    P P     A ++   P M       S S +A      +  S +SP
Sbjct: 346  ------PEKGPTLA-PSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASP 398

Query: 2043 QQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQP--GMQPQPGMHQQPS 2100
                Q L      P    +F    T+  V+NQP    QP L SQ      P P       
Sbjct: 399  FPASQAL------PSYPHSF-PPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRL 451

Query: 2101 LQNLNAMQAGVPRPG-VPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQL 2159
            L N NA       PG  PP   A    +P       ++  H+ +                
Sbjct: 452  LANSNA------HPGPFPPSTGAQSTAHPP------VSTHHHHH---------------- 483

Query: 2160 LQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQ 2219
             QQQQQQQQQQQQQQQQQQ   G +G          P  PG +P  ++       H    
Sbjct: 484  -QQQQQQQQQQQQQQQQQQQHHGNSG----------PPPPGAFPHPLEGGSSHHAHPYAM 532

Query: 2220 GSSMGQMAA------------QMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQI 2267
              S+G +                    Q G  G    S+ N   +  Q            
Sbjct: 533  SPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQ 592

Query: 2268 GSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHS--SP 2325
            G  G P P  P   + +            ++T ++    SPA  ++  P   PP+   +P
Sbjct: 593  GPQGAPYPFPPVPTVTTS--------SATLSTVIATVASSPAGYKTASPPGPPPYGKRAP 644

Query: 2326 SPRIQPQPSPHHVSPQTGSP 2345
            SP      +P    P  GSP
Sbjct: 645  SPGAYKTATPPGYKP--GSP 662



 Score = 63.2 bits (152), Expect = 3e-09
 Identities = 147/682 (21%), Positives = 222/682 (32%), Gaps = 119/682 (17%)

Query: 408  LGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQP-QV 466
            +G    G  +++G    G+Q+      P P  P S+  + A+ G P    P T +    +
Sbjct: 233  MGPKGGGAASSVGGPNGGKQH------PPPTTPISVSSSGAS-GAPPTKPPTTPVGGGNL 285

Query: 467  PGQQPAQPQTHQQMRTLNPLGNNPMNIPAG---GITTDQQPPNLISESALPTSLGATNPL 523
            P   P     H       P    P+N  +    G+     P +L S  A+   +G   P 
Sbjct: 286  PSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPG 345

Query: 524  MNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAAL 583
               G       TL+  P + PP+S+             +R              P  ++ 
Sbjct: 346  PEKGP------TLAPSPHSLPPASSSAP-------APPMRF-------------PYSSSS 379

Query: 584  KDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKI-YKIQKELEEKRRSRLHKQGILG 642
                  +  + +       + ++ +   Y H         +  +  +  +  L  Q +  
Sbjct: 380  SSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWS 439

Query: 643  NQPALPAP--------GAQP-PVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGN 693
              P  P P         A P P  P        + P+S   +  Q  Q            
Sbjct: 440  QGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQ 499

Query: 694  VQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSR---MPQPPNMMGAHTNNMMAQAP 750
             Q      GP       H ++  S       A+SPS     P PP    AH     +Q  
Sbjct: 500  QQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGP--AHLPPPHSQV- 556

Query: 751  AQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPV 810
            + SQ  P     SSS   S         +  SQG  P  + P+P    GPQ +  P PPV
Sbjct: 557  SYSQAGPNGPPVSSSSNSS---------SSTSQGSYP-CSHPSPSQ--GPQGAPYPFPPV 604

Query: 811  -------------------------TQSPLHPTPPPASTAAGMPSLQHT-TPPGMTPPQP 844
                                     T SP  P PPP    A  P    T TPPG  P  P
Sbjct: 605  PTVTTSSATLSTVIATVASSPAGYKTASP--PGPPPYGKRAPSPGAYKTATPPGYKPGSP 662

Query: 845  AAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATP 904
             +  +  TP    G +P   PG+    + T             V P P  P      A P
Sbjct: 663  PS-FRTGTPPGYRGTSPPAGPGTFKPGSPT-------------VGPGPLPP------AGP 702

Query: 905  QSSQQQPTPVHAQPPGTPLS--QAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTE 962
                  P P  A   G PLS  Q          TP S      +   P   V V    ++
Sbjct: 703  SGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQ 762

Query: 963  TQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAE---QKSEPMEVDEKKPEVKV 1019
            +   +   D G +    RS++    L+G+   K+  D+ E   +++E    +EK+ E + 
Sbjct: 763  SARFNKHLDRGFNSC-ARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKERERER 821

Query: 1020 EVKEEEESSSNGTASQSTSPSQ 1041
            E ++E E        +S   +Q
Sbjct: 822  EREKEREREKERELERSVKLAQ 843



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 66/305 (21%), Positives = 100/305 (32%), Gaps = 40/305 (13%)

Query: 769  SVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLH-PTPPPASTAAG 827
            S G+ Q PA+        P +  P       P+AS  P P VT +  H P  PP S    
Sbjct: 148  SSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSR--- 204

Query: 828  MPSLQHTTPPGMTPPQP-----------AAPTQPSTPVSSSGQTPTPTPGSVPSATQTQS 876
                    PPG  PP P           + P        ++     P  G       T  
Sbjct: 205  ----MFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPI 260

Query: 877  TPTVQAAAQAQVTPQPQTPVQPPSV--ATPQSSQQQPTPVHAQPPG-TPLSQAAAS---- 929
            + +   A+ A  T  P TPV   ++  A P ++    TP    PP   PL+ A+AS    
Sbjct: 261  SVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGL 320

Query: 930  ----IDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEM-- 983
                +   +P+P ++         PGP+      K  T A      P  S   P   M  
Sbjct: 321  GAQPLPGHLPSPHAMGQG-MGGLPPGPE------KGPTLAPSPHSLPPASSSAPAPPMRF 373

Query: 984  -MEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQP 1042
                    ++     +  +   + P    +  P            S +    + T PS P
Sbjct: 374  PYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLP 433

Query: 1043 RKKIF 1047
             + ++
Sbjct: 434  SQAVW 438



 Score = 45.1 bits (105), Expect = 9e-04
 Identities = 43/144 (29%), Positives = 57/144 (39%), Gaps = 26/144 (18%)

Query: 1832 ATMNTRNVPQQSLPS--PTSAPPGTP-----TQQPSTPQTPQPPAQPQPSPVSMSPAGFP 1884
            AT++T      S P+   T++PPG P        P   +T  PP     SP S      P
Sbjct: 612  ATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPP 671

Query: 1885 SVARTQPPTTVSTGKPTSQV--PAPPPPA--------QPPPAAVE-----AARQIEREAQ 1929
                T PP    T KP S    P P PPA         PPPAA       +A QI++E  
Sbjct: 672  GYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPA 731

Query: 1930 QQQHLYRVNINNSMPPGRTGMGTP 1953
            ++         + +PP R+    P
Sbjct: 732  EEYE----TPESPVPPARSPSPPP 751



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 32/97 (32%), Positives = 44/97 (45%), Gaps = 8/97 (8%)

Query: 1848 TSAPPGTPTQQPSTPQT---PQPPAQPQ--PS--PVSMSPAGFPSVARTQPPTTVSTGKP 1900
            TS P G  T +P +P     P PPA P   PS  P   +PA  P ++ TQ     +    
Sbjct: 676  TSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYE 735

Query: 1901 TSQVPAPPPPA-QPPPAAVEAARQIEREAQQQQHLYR 1936
            T + P PP  +  PPP  V+      + A+  +HL R
Sbjct: 736  TPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDR 772



 Score = 41.6 bits (96), Expect = 0.010
 Identities = 66/302 (21%), Positives = 94/302 (31%), Gaps = 58/302 (19%)

Query: 704 RAASPMNHSVQM--NSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQF 761
           R+ SP  +S     N   S  G++  P+R   PP +          Q P  +   P+  F
Sbjct: 129 RSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSP-----QPPDSTPRQPEASF 183

Query: 762 PSSSGAMSVGMGQP--PAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPV--------- 810
                    G   P  P  + + Q   PGA  P+P    G     L  PP+         
Sbjct: 184 EPHPSVTPTGYHAPMEPPTSRMFQAP-PGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAAS 242

Query: 811 -----TQSPLHPTPP-PASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPT 864
                     HP P  P S ++   S       G  P +P     P+TPV        P 
Sbjct: 243 SVGGPNGGKQHPPPTTPISVSSSGAS-------GAPPTKP-----PTTPVGGGNLPSAPP 290

Query: 865 PGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQ------- 917
           P + P  T     P         + P       PP +         P+P HA        
Sbjct: 291 PANFPHVTPNLPPPPA-------LRPLNNASASPPGLGAQPLPGHLPSP-HAMGQGMGGL 342

Query: 918 PPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKG 977
           PPG       A      P+P S+  A +++  P    P     + + A  +      S  
Sbjct: 343 PPGPEKGPTLA------PSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSA 396

Query: 978 EP 979
            P
Sbjct: 397 SP 398



 Score = 41.2 bits (95), Expect = 0.012
 Identities = 66/279 (23%), Positives = 87/279 (31%), Gaps = 72/279 (25%)

Query: 1810 HKLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSA------------------- 1850
            H  +QQQ Q + QQ Q  +++    N+   P  + P P                      
Sbjct: 481  HHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLR 540

Query: 1851 --PPGTPTQQPSTPQTPQPPAQPQPSPVSMS------------PAGFPSVAR-------- 1888
              PPG     P   Q     A P   PVS S            P   PS ++        
Sbjct: 541  PYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYP 600

Query: 1889 -------TQPPTTVST----------GKPTSQVPAPPPPAQ--PPPAAVEAARQIEREAQ 1929
                   T    T+ST          G  T+  P PPP  +  P P A + A     +  
Sbjct: 601  FPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPG 660

Query: 1930 QQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLP 1989
                    +     PPG  G   P     P +     P    GP+ P+ P G     P P
Sbjct: 661  SPP-----SFRTGTPPGYRGTSPPA---GPGTFKPGSPTVGPGPLPPAGPSG-LPSLPPP 711

Query: 1990 QQQPMPGLPRPVISMQAQAA--VAGPRMPSVQPPRSISP 2026
               P  G P     ++ + A     P  P V P RS SP
Sbjct: 712  PAAPASGPPLSATQIKQEPAEEYETPESP-VPPARSPSP 749



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 74/314 (23%), Positives = 104/314 (33%), Gaps = 52/314 (16%)

Query: 1832 ATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQ------TPQPPAQPQPSPVSMSPAGFPS 1885
            A  ++ +    S  SP  A    P+   S P       + QPP   QPS  S       +
Sbjct: 383  AAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQ------A 436

Query: 1886 VARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAA--------RQIEREAQQQQHLYRV 1937
            V    PP     G+  +   A P P  P   A   A           +++ QQQQ   + 
Sbjct: 437  VWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQ 496

Query: 1938 NINNSMPPGRTGMGTPGSQMAPV---SLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPM 1994
                    G +G   PG+   P+   S +   P  +S P + S+ P      P P   P 
Sbjct: 497  QQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMS-PSLGSLRP----YPPGPAHLPP 551

Query: 1995 PGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQ------- 2047
            P         Q   + AGP  P V    + S S  Q       S  SP Q  Q       
Sbjct: 552  P-------HSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPC--SHPSPSQGPQGAPYPFP 602

Query: 2048 -VLNILKSNPQL--MAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNL 2104
             V  +  S+  L  + A +    A Y    P   P  G ++     P PG ++  +    
Sbjct: 603  PVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRA-----PSPGAYKTATPPGY 657

Query: 2105 NAMQAGVPRPGVPP 2118
                    R G PP
Sbjct: 658  KPGSPPSFRTGTPP 671



 Score = 32.0 bits (71), Expect = 7.5
 Identities = 68/292 (23%), Positives = 92/292 (31%), Gaps = 47/292 (16%)

Query: 2086 QPGMQPQPGMHQQPSLQNLNAMQAGV---------PRPGVPPQQQAMGGLNPQGQALNIM 2136
            Q      P ++   S++N +   +G+         P P  PP  Q       Q +A    
Sbjct: 126  QDNRSTSPSIYSPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEP 185

Query: 2137 NPGHNPN--MASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQ 2194
            +P   P    A M P    M        Q          Q    G+ G+  G        
Sbjct: 186  HPSVTPTGYHAPMEPPTSRMF-------QAPPGAPPPHPQLYPGGTGGVLSG-------- 230

Query: 2195 QPQGP--GGYPPAMQQQQRMQQH----LPLQGSSMGQMAAQM----------GQLGQMGQ 2238
             P GP  GG   ++      +QH     P+  SS G   A            G L     
Sbjct: 231  PPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPP 290

Query: 2239 PGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMS-PQQHMLSGQPQASHLPGQQI 2297
            P      TPN+      R L         G   QP P   P  H + GQ      PG + 
Sbjct: 291  PANFPHVTPNLPPPPALRPLNNASASPP-GLGAQPLPGHLPSPHAM-GQGMGGLPPGPEK 348

Query: 2298 ATSLSNQVRS--PAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHP 2347
              +L+    S  PA   +P P  + P+SS S       S    S  + SP P
Sbjct: 349  GPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFP 400


>gi|11067749 bromodomain containing protein 3 [Homo sapiens]
          Length = 726

 Score = 92.0 bits (227), Expect = 6e-18
 Identities = 90/315 (28%), Positives = 122/315 (38%), Gaps = 57/315 (18%)

Query: 839  MTPPQPAAP-TQPSTPVSSSGQTPTPTPGSVPSATQTQSTP-TVQAAAQAQVTPQPQTPV 896
            + PP P     +P+    S+G        SV  AT  QS P TV        TP P    
Sbjct: 147  LLPPAPKGKGRKPAAGAQSAGTQQVAAVSSVSPATPFQSVPPTVSQTPVIAATPVPTITA 206

Query: 897  QPPSVATPQSSQQQP--TPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDV 954
               SV  P ++   P  TP+    P TP       +  +  T +   SA T S+   P  
Sbjct: 207  NVTSVPVPPAAAPPPPATPIVPVVPPTPPVVKKKGVKRKADTTTPTTSAITASRSESP-- 264

Query: 955  PVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKK 1014
            P L             DP ++K   R E       G   +K           P + D + 
Sbjct: 265  PPLS------------DPKQAKVVARRE------SGGRPIK-----------PPKKDLED 295

Query: 1015 PEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPE-SLPF 1073
             EV                     P    KK    E LR       E L ++    + PF
Sbjct: 296  GEV---------------------PQHAGKKGKLSEHLRYCDSILREMLSKKHAAYAWPF 334

Query: 1074 RQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKT 1133
             +PVD + L + DY DI+K+PMDLST+KRK+D  +Y +   +  DV LMF+N + YN   
Sbjct: 335  YKPVDAEALELHDYHDIIKHPMDLSTVKRKMDGREYPDAQGFAADVRLMFSNCYKYNPPD 394

Query: 1134 SRVYKFCSKLAEVFE 1148
              V     KL +VFE
Sbjct: 395  HEVVAMARKLQDVFE 409



 Score = 74.7 bits (182), Expect = 1e-12
 Identities = 39/127 (30%), Positives = 69/127 (54%), Gaps = 4/127 (3%)

Query: 1030 NGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFD 1089
            N    + ++PS+P +K  + + ++  ++ TL     +   + PF QPVD   L +PDY  
Sbjct: 20   NPPPPEVSNPSKPGRKTNQLQYMQNVVVKTLW----KHQFAWPFYQPVDAIKLNLPDYHK 75

Query: 1090 IVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQ 1149
            I+KNPMD+ TIK++L+   Y    + + D   MF N ++YN+ T  +      L ++F Q
Sbjct: 76   IIKNPMDMGTIKKRLENNYYWSASECMQDFNTMFTNCYIYNKPTDDIVLMAQALEKIFLQ 135

Query: 1150 EIDPVMQ 1156
            ++  + Q
Sbjct: 136  KVAQMPQ 142



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 43/167 (25%), Positives = 69/167 (41%), Gaps = 31/167 (18%)

Query: 771 GMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPP-VTQSPLHPTPPPASTAAGMP 829
           G G+ PA    S G    AA+ +    + P       PP V+Q+P+    P  +  A + 
Sbjct: 154 GKGRKPAAGAQSAGTQQVAAVSS----VSPATPFQSVPPTVSQTPVIAATPVPTITANVT 209

Query: 830 SLQHTTPPGMTPPQPAAPTQPSTP-------------VSSSGQTPTPTPGSVPSATQTQS 876
           S+    PP   PP PA    P  P             V     T TPT  ++ +A++++S
Sbjct: 210 SVP--VPPAAAPPPPAT---PIVPVVPPTPPVVKKKGVKRKADTTTPTTSAI-TASRSES 263

Query: 877 TPTVQAAAQAQVTPQPQT---PVQPPSVATPQSSQQQPTPVHAQPPG 920
            P +    QA+V  + ++   P++PP     +  +    P HA   G
Sbjct: 264 PPPLSDPKQAKVVARRESGGRPIKPPK----KDLEDGEVPQHAGKKG 306



 Score = 39.3 bits (90), Expect = 0.047
 Identities = 26/84 (30%), Positives = 38/84 (45%), Gaps = 3/84 (3%)

Query: 1840 PQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGK 1899
            P  ++ +  ++ P  P   P  P TP  P  P P+P  +   G    A T  PTT  +  
Sbjct: 200  PVPTITANVTSVPVPPAAAPPPPATPIVPVVP-PTPPVVKKKGVKRKADTTTPTT--SAI 256

Query: 1900 PTSQVPAPPPPAQPPPAAVEAARQ 1923
              S+  +PPP + P  A V A R+
Sbjct: 257  TASRSESPPPLSDPKQAKVVARRE 280



 Score = 35.4 bits (80), Expect = 0.68
 Identities = 27/92 (29%), Positives = 38/92 (41%), Gaps = 12/92 (13%)

Query: 1845 PSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVS--TGKPTS 1902
            P+  +   GT      +  +P  P Q  P  VS +P     +A T  PT  +  T  P  
Sbjct: 159  PAAGAQSAGTQQVAAVSSVSPATPFQSVPPTVSQTPV----IAATPVPTITANVTSVPVP 214

Query: 1903 QVPAPPPPAQ------PPPAAVEAARQIEREA 1928
               APPPPA       PP   V   + ++R+A
Sbjct: 215  PAAAPPPPATPIVPVVPPTPPVVKKKGVKRKA 246



 Score = 32.7 bits (73), Expect = 4.4
 Identities = 27/114 (23%), Positives = 52/114 (45%), Gaps = 18/114 (15%)

Query: 950  PGPDVPVLEMKTETQ--AEDTEPDPGESKGEPR-----SEMME------EDLQGASQV-- 994
            P P  P++    E+   +E++  D G S  E       +E+ E      E L   SQ   
Sbjct: 426  PAPAAPMVSKGAESSRSSEESSSDSGSSDSEEERATRLAELQEQLKAVHEQLAALSQAPV 485

Query: 995  ---KEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKK 1045
               K++ +  E++ +  + +++K + KV+ +EE+++     A Q+     P KK
Sbjct: 486  NKPKKKKEKKEKEKKKKDKEKEKEKHKVKAEEEKKAKVAPPAKQAQQKKAPAKK 539


>gi|164419758 bromodomain containing 2 [Homo sapiens]
          Length = 801

 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 112/482 (23%), Positives = 174/482 (36%), Gaps = 90/482 (18%)

Query: 701  MGPRAASP---------MNHSVQMNSMGSVPGMAISPSRMPQP----PNMMGAHTNNMMA 747
            +GP AA+P         +    +  +M SVP + ++P+  P P    P   G  TN +  
Sbjct: 22   LGPEAAAPGKRIRKPSLLYEGFESPTMASVPALQLTPANPPPPEVSNPKKPGRVTNQLQY 81

Query: 748  QAPAQSQFLPQNQF--PSSSGAMSVGMGQPPAQTGVSQGQVPGAA---LPNPLNMLGPQA 802
                  + L ++QF  P      +V +G P     + Q    G     L N       + 
Sbjct: 82   LHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASEC 141

Query: 803  SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSS--SGQT 860
             Q      T   ++  P            +       + PQ       + P +S   G  
Sbjct: 142  MQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKKGAK 201

Query: 861  PTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPV------QPPSVATP-----QSSQQ 909
                 GSV SA Q  +  +V   A    TP P+ P        P  +++P      S+  
Sbjct: 202  LAALQGSVTSAHQVPAVSSVSHTAL--YTPPPEIPTTVLNIPHPSVISSPLLKSLHSAGP 259

Query: 910  QPTPVHAQPPGTPLSQAAA---SIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAE 966
                V A PP  PL++        D   PTP+++ +  + +  PG   P        + E
Sbjct: 260  PLLAVTAAPPAQPLAKKKGVKRKADTTTPTPTAILAPGSPASPPGSLEPKAARLPPMRRE 319

Query: 967  DTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEE 1026
               P     K  P S+   +                          KK ++  ++K    
Sbjct: 320  SGRPIKPPRKDLPDSQQQHQS------------------------SKKGKLSEQLKH--- 352

Query: 1027 SSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPD 1086
               NG   +                    L+    A Y     + PF +PVD   LG+ D
Sbjct: 353  --CNGILKE--------------------LLSKKHAAY-----AWPFYKPVDASALGLHD 385

Query: 1087 YFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEV 1146
            Y DI+K+PMDLST+KRK++   Y++  ++  DV LMF+N + YN     V     KL +V
Sbjct: 386  YHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDV 445

Query: 1147 FE 1148
            FE
Sbjct: 446  FE 447



 Score = 76.3 bits (186), Expect = 3e-13
 Identities = 40/117 (34%), Positives = 64/117 (54%), Gaps = 1/117 (0%)

Query: 1040 SQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLST 1099
            S P+K      +L+      ++AL++    + PFRQPVD   LG+PDY  I+K PMD+ T
Sbjct: 67   SNPKKPGRVTNQLQYLHKVVMKALWKHQ-FAWPFRQPVDAVKLGLPDYHKIIKQPMDMGT 125

Query: 1100 IKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQ 1156
            IKR+L+   Y    + + D   MF N ++YN+ T  +      L ++F Q++  + Q
Sbjct: 126  IKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQ 182



 Score = 35.4 bits (80), Expect = 0.68
 Identities = 34/136 (25%), Positives = 59/136 (43%), Gaps = 15/136 (11%)

Query: 949  QPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKE---ETDIAEQKS 1005
            +PGP +PV           T   PG +K    S   E   + +S+ +E   E D  E++S
Sbjct: 459  EPGP-LPV----------STAMPPGLAKSSSESSSEESSSESSSEEEEEEDEEDEEEEES 507

Query: 1006 EPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSP-SQPRKKIFKPEELRQALMPTLEALY 1064
            E  + +E++     E++E+  +     A+ S  P S+P++K  K E+ ++          
Sbjct: 508  ESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRA 567

Query: 1065 RQDPESLPFRQPVDPQ 1080
              D +    R P  PQ
Sbjct: 568  GADEDDKGPRAPRPPQ 583



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 31/115 (26%), Positives = 49/115 (42%), Gaps = 16/115 (13%)

Query: 1948 TGMGTPGSQMAPVSLNVPRPNQVSGPVMPSM---PPGQWQQAPLPQQQPM---PGLPRPV 2001
            T + TP  ++    LN+P P+ +S P++ S+    P        P  QP+    G+ R  
Sbjct: 224  TALYTPPPEIPTTVLNIPHPSVISSPLLKSLHSAGPPLLAVTAAPPAQPLAKKKGVKRKA 283

Query: 2002 -ISMQAQAAVAGPRMPSVQPPRSISPSAL------QDLLRTLKSPSS--PQQQQQ 2047
              +     A+  P  P+  PP S+ P A       ++  R +K P    P  QQQ
Sbjct: 284  DTTTPTPTAILAPGSPA-SPPGSLEPKAARLPPMRRESGRPIKPPRKDLPDSQQQ 337


>gi|4826806 bromodomain containing 2 [Homo sapiens]
          Length = 801

 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 112/482 (23%), Positives = 174/482 (36%), Gaps = 90/482 (18%)

Query: 701  MGPRAASP---------MNHSVQMNSMGSVPGMAISPSRMPQP----PNMMGAHTNNMMA 747
            +GP AA+P         +    +  +M SVP + ++P+  P P    P   G  TN +  
Sbjct: 22   LGPEAAAPGKRIRKPSLLYEGFESPTMASVPALQLTPANPPPPEVSNPKKPGRVTNQLQY 81

Query: 748  QAPAQSQFLPQNQF--PSSSGAMSVGMGQPPAQTGVSQGQVPGAA---LPNPLNMLGPQA 802
                  + L ++QF  P      +V +G P     + Q    G     L N       + 
Sbjct: 82   LHKVVMKALWKHQFAWPFRQPVDAVKLGLPDYHKIIKQPMDMGTIKRRLENNYYWAASEC 141

Query: 803  SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSS--SGQT 860
             Q      T   ++  P            +       + PQ       + P +S   G  
Sbjct: 142  MQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQEEQELVVTIPKNSHKKGAK 201

Query: 861  PTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPV------QPPSVATP-----QSSQQ 909
                 GSV SA Q  +  +V   A    TP P+ P        P  +++P      S+  
Sbjct: 202  LAALQGSVTSAHQVPAVSSVSHTAL--YTPPPEIPTTVLNIPHPSVISSPLLKSLHSAGP 259

Query: 910  QPTPVHAQPPGTPLSQAAA---SIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAE 966
                V A PP  PL++        D   PTP+++ +  + +  PG   P        + E
Sbjct: 260  PLLAVTAAPPAQPLAKKKGVKRKADTTTPTPTAILAPGSPASPPGSLEPKAARLPPMRRE 319

Query: 967  DTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEE 1026
               P     K  P S+   +                          KK ++  ++K    
Sbjct: 320  SGRPIKPPRKDLPDSQQQHQS------------------------SKKGKLSEQLKH--- 352

Query: 1027 SSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPD 1086
               NG   +                    L+    A Y     + PF +PVD   LG+ D
Sbjct: 353  --CNGILKE--------------------LLSKKHAAY-----AWPFYKPVDASALGLHD 385

Query: 1087 YFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEV 1146
            Y DI+K+PMDLST+KRK++   Y++  ++  DV LMF+N + YN     V     KL +V
Sbjct: 386  YHDIIKHPMDLSTVKRKMENRDYRDAQEFAADVRLMFSNCYKYNPPDHDVVAMARKLQDV 445

Query: 1147 FE 1148
            FE
Sbjct: 446  FE 447



 Score = 76.3 bits (186), Expect = 3e-13
 Identities = 40/117 (34%), Positives = 64/117 (54%), Gaps = 1/117 (0%)

Query: 1040 SQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLST 1099
            S P+K      +L+      ++AL++    + PFRQPVD   LG+PDY  I+K PMD+ T
Sbjct: 67   SNPKKPGRVTNQLQYLHKVVMKALWKHQ-FAWPFRQPVDAVKLGLPDYHKIIKQPMDMGT 125

Query: 1100 IKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQ 1156
            IKR+L+   Y    + + D   MF N ++YN+ T  +      L ++F Q++  + Q
Sbjct: 126  IKRRLENNYYWAASECMQDFNTMFTNCYIYNKPTDDIVLMAQTLEKIFLQKVASMPQ 182



 Score = 35.4 bits (80), Expect = 0.68
 Identities = 34/136 (25%), Positives = 59/136 (43%), Gaps = 15/136 (11%)

Query: 949  QPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKE---ETDIAEQKS 1005
            +PGP +PV           T   PG +K    S   E   + +S+ +E   E D  E++S
Sbjct: 459  EPGP-LPV----------STAMPPGLAKSSSESSSEESSSESSSEEEEEEDEEDEEEEES 507

Query: 1006 EPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSP-SQPRKKIFKPEELRQALMPTLEALY 1064
            E  + +E++     E++E+  +     A+ S  P S+P++K  K E+ ++          
Sbjct: 508  ESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRA 567

Query: 1065 RQDPESLPFRQPVDPQ 1080
              D +    R P  PQ
Sbjct: 568  GADEDDKGPRAPRPPQ 583



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 31/115 (26%), Positives = 49/115 (42%), Gaps = 16/115 (13%)

Query: 1948 TGMGTPGSQMAPVSLNVPRPNQVSGPVMPSM---PPGQWQQAPLPQQQPM---PGLPRPV 2001
            T + TP  ++    LN+P P+ +S P++ S+    P        P  QP+    G+ R  
Sbjct: 224  TALYTPPPEIPTTVLNIPHPSVISSPLLKSLHSAGPPLLAVTAAPPAQPLAKKKGVKRKA 283

Query: 2002 -ISMQAQAAVAGPRMPSVQPPRSISPSAL------QDLLRTLKSPSS--PQQQQQ 2047
              +     A+  P  P+  PP S+ P A       ++  R +K P    P  QQQ
Sbjct: 284  DTTTPTPTAILAPGSPA-SPPGSLEPKAARLPPMRRESGRPIKPPRKDLPDSQQQ 337


>gi|33286444 mastermind-like 2 [Homo sapiens]
          Length = 1156

 Score = 86.7 bits (213), Expect = 3e-16
 Identities = 139/535 (25%), Positives = 188/535 (35%), Gaps = 134/535 (25%)

Query: 1841 QQSLPSPTSAPPGTPTQQPSTPQTPQPPA-QPQPSPVSMSPA---GFPSVARTQPPTTVS 1896
            Q+S P P+        +   +P   Q P+  PQ  P S  PA      +++ + P  +V 
Sbjct: 349  QRSTPRPSLPMEKIVIKSEYSPGLTQGPSGSPQLRPPSAGPAFSMANSALSTSSPIPSVP 408

Query: 1897 TGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQ 1956
              +   Q  +    A P    V  A+Q+++ A  +Q   R+  +            P S 
Sbjct: 409  QSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSALPSSA 468

Query: 1957 MAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMP 2016
                    P P       +PS  P   QQ   PQ  PMPG             VAG    
Sbjct: 469  G-------PSPGPFGQEKIPS--PSFGQQTFSPQSSPMPG-------------VAGG--- 503

Query: 2017 SVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNIL-KSNPQ-LMAAFIKQRTAKYVANQ 2074
                      S    ++      + P  Q   L++L +  PQ L  +FI         N 
Sbjct: 504  ----------SGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFI---------NN 544

Query: 2075 PGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALN 2134
            P           P M+P+ G      L + N+ QA    P V P Q              
Sbjct: 545  P----------HPAMEPRQG--NTKPLFHFNSDQANQQMPSVLPSQN------------- 579

Query: 2135 IMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQ 2194
                          P      ++Q  QQQQQQQQQQQQQQQQQQ               Q
Sbjct: 580  -------------KPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQ---------------Q 611

Query: 2195 QPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQ 2254
            Q Q         QQQQ+ Q  +  Q     Q +    Q  Q  Q           QQ  Q
Sbjct: 612  QQQ---------QQQQQQQSSISAQQQQQQQSSISAQQQQQQQQ-----------QQQQQ 651

Query: 2255 QRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQ--IATSLSNQVRSPAPVQ 2312
            Q+  QQQQ +QQ     QP    P Q +L      S LP QQ  +   + NQ  +    Q
Sbjct: 652  QQQQQQQQQQQQQQPSSQPAQSLPSQPLLR-----SPLPLQQKLLLQQMQNQPIAGMGYQ 706

Query: 2313 SPRPQSQPPHSSPSPRIQPQPSPHHVS-PQTGSPHPGLAVTMASSIDQGHLGNPE 2366
              + Q Q  HS       P PSP+  S P TGS   G   +  S ++Q  +G  +
Sbjct: 707  VSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGS---GYMNSQQSLLNQQLMGKKQ 758



 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 109/517 (21%), Positives = 160/517 (30%), Gaps = 79/517 (15%)

Query: 1887 ARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPG 1946
            AR     T +T    +    PPPPA PP A+  AA           H ++ ++ NS   G
Sbjct: 86   ARKAGKHTKATATAATTTAPPPPPAAPPAASQAAATAAPPPPPDYHHHHQQHLLNSSNNG 145

Query: 1947 RTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQ-WQQAPLPQQQPMPGLPRPVISMQ 2005
             +G G  G Q  P S    + N     +  S+   Q    +P   ++P   +    + + 
Sbjct: 146  GSG-GINGEQQPPASTPGDQRNSALIALQGSLKRKQVVNLSPANSKRPNGFVDNSFLDI- 203

Query: 2006 AQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQ 2065
             +    G  + + Q    I+    Q +  TL    +P ++    N L S+       +  
Sbjct: 204  -KRIRVGENLSAGQGGLQINNGQSQIMSGTLPMSQAPLRK---TNTLPSHTHSPGNGLFN 259

Query: 2066 RTAKYVANQPG-----MQPQPGLQSQPGMQP-----QPGMH-QQPSLQNL---------- 2104
               K V  +PG      +   G  +Q  + P      PG     P LQ L          
Sbjct: 260  MGLKEVKKEPGETLSCSKHMDGQMTQENIFPNRYGDDPGEQLMDPELQELFNELTNISVP 319

Query: 2105 --------------------------NAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNP 2138
                                         Q   PRP +P ++  +      G       P
Sbjct: 320  PMSDLELENMINATIKQDDPFNIDLGQQSQRSTPRPSLPMEKIVIKSEYSPGLT---QGP 376

Query: 2139 GHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGM----AGGMAGHGQFQ 2194
              +P +   +      +    L          Q Q Q Q GS       +     H Q Q
Sbjct: 377  SGSPQLRPPSAGPAFSMANSALSTSSPIPSVPQSQAQPQTGSGASRALPSWQEVSHAQ-Q 435

Query: 2195 QPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPG-LGADSTPNIQQAL 2253
              Q         + QQ  QQH P   S++   A           PG  G +  P+     
Sbjct: 436  LKQIAANRQQHARMQQHQQQHQPTNWSALPSSAGP--------SPGPFGQEKIPSPSFGQ 487

Query: 2254 QQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLP--GQQIATSLSNQ-VRSPAP 2310
            Q    Q   M    G  GQ   M+   +      Q  HL    QQ    LS   + +P P
Sbjct: 488  QTFSPQSSPMPGVAGGSGQSKVMANYMYKAGPSAQGGHLDVLMQQKPQDLSRSFINNPHP 547

Query: 2311 VQSPRPQSQPP--HSSPSPRIQPQPSPHHVSPQTGSP 2345
               PR  +  P  H +     Q  PS   V P    P
Sbjct: 548  AMEPRQGNTKPLFHFNSDQANQQMPS---VLPSQNKP 581



 Score = 41.6 bits (96), Expect = 0.010
 Identities = 115/574 (20%), Positives = 194/574 (33%), Gaps = 120/574 (20%)

Query: 1870 QPQPSPVSMS------PAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQ 1923
            Q +P  +S S      PA  P    T+P    ++ +   Q+P+  P +Q  P+ +   +Q
Sbjct: 531  QQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLP-SQNKPSLLHYTQQ 589

Query: 1924 IEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQW 1983
             +++ QQQQ   +          +        Q    S++  +  Q    +       Q 
Sbjct: 590  QQQQQQQQQQQQQQQQQQQQQQQQQQQ----QQQQQSSISAQQQQQQQSSISAQQQQQQQ 645

Query: 1984 QQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRT-----LKS 2038
            QQ    QQQ      +      +Q A + P  P ++ P  +    L   ++      +  
Sbjct: 646  QQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQMQNQPIAGMGY 705

Query: 2039 PSSPQQQQQVLNILK------------SNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQ 2086
              S QQ+Q   +++             SNP   + ++  + +  + NQ  M  +  LQ Q
Sbjct: 706  QVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQS--LLNQQLMGKKQTLQRQ 763

Query: 2087 PGMQPQPGMHQQPSLQNLNAM--------QAGVPRPGVPPQQQAMGGLNPQGQ------- 2131
               Q Q  + QQ  L +   +            P P    Q++ +G + P  Q       
Sbjct: 764  IMEQKQQLLLQQQMLADAEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGGSST 823

Query: 2132 -ALN--------------------IMNPGHNPNMASMNPQYREMLR-------------- 2156
             +LN                    +++  H   M S++   + M                
Sbjct: 824  ISLNSNQALANPVSTHTILTPNSSLLSTSHGTRMPSLSTAVQNMGMYGNLPCNQPNTYSV 883

Query: 2157 ----RQLLQQQQQQQQQQQQQQ-----------QQQQGSAGMAGGMAGHGQFQQPQGPGG 2201
                 QL QQ+  +Q    Q                   A    G  G+ Q  +P     
Sbjct: 884  TSGMNQLTQQRNPKQLLANQNNPMMPRPPTLGPSNNNNVATFGAGSVGNSQQLRPNLT-- 941

Query: 2202 YPPAMQQQQRMQQHLPLQGSSMGQMAAQMG---------QLGQMGQPGLGADSTPNIQQA 2252
            +  A    QR    +    ++    A+Q G           G     G  A  TPN  Q+
Sbjct: 942  HSMASMPPQRTSNVMITSNTTAPNWASQEGTSKQQEALTSAGVRFPTGTPAAYTPN--QS 999

Query: 2253 LQQRILQQQQMKQQIGSPG------QPNPMSPQQHMLSGQP----QASHLPGQQIATS-L 2301
            LQQ +  QQ  ++ +  P       Q  PM+     L+GQ     +  +L   Q++T  L
Sbjct: 1000 LQQAVGSQQFSQRAVAPPNQLTPAVQMRPMNQMSQTLNGQTMGPLRGLNLRPNQLSTQIL 1059

Query: 2302 SNQVRSPAPV-QSPRPQSQPPHSSPSPRIQPQPS 2334
             N  +S   + QS    +QPP  +PS    P  S
Sbjct: 1060 PNLNQSGTGLNQSRTGINQPPSLTPSNFPSPNQS 1093



 Score = 41.6 bits (96), Expect = 0.010
 Identities = 113/488 (23%), Positives = 161/488 (32%), Gaps = 66/488 (13%)

Query: 1813 RQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQ 1872
            +QQQ Q + QQ Q  +++ +    +   QQS  S          QQ    Q  Q   Q Q
Sbjct: 604  QQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQ 663

Query: 1873 PSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQ 1932
              P S      PS    + P  +       Q+       Q  P A    +  +++ Q Q 
Sbjct: 664  QQPSSQPAQSLPSQPLLRSPLPLQQKLLLQQM-------QNQPIAGMGYQVSQQQRQDQH 716

Query: 1933 HLYRVNINNSMPPG-----RTGMGTPGSQMAPVSLNVPRPNQ-VSGPVMPSMPPGQWQQA 1986
             +   N   S  P       TG G   SQ + ++  +    Q +   +M        QQ 
Sbjct: 717  SVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLNQQLMGKKQTLQRQIMEQKQQLLLQQQ 776

Query: 1987 PL-------PQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSP 2039
             L       PQ Q    L RP    + Q    G   P+ Q     S  +L    + L +P
Sbjct: 777  MLADAEKIAPQDQINRHLSRPPPDYKDQRRNVGNMQPTAQYSGGSSTISLNS-NQALANP 835

Query: 2040 SSPQQQQQVLNILKSNPQLMAAFIKQR-----TAKYVANQPGMQP--QPGLQSQPGMQPQ 2092
             S         IL  N  L++     R     TA       G  P  QP   S      Q
Sbjct: 836  VSTH------TILTPNSSLLSTSHGTRMPSLSTAVQNMGMYGNLPCNQPNTYSVTSGMNQ 889

Query: 2093 PGMHQQPSLQNLNAMQAGVPR-PGVPPQQQ---AMGGLNPQGQALNIMNPGHNPNMASMN 2148
                + P     N     +PR P + P      A  G    G +   + P    +MASM 
Sbjct: 890  LTQQRNPKQLLANQNNPMMPRPPTLGPSNNNNVATFGAGSVGNSQQ-LRPNLTHSMASMP 948

Query: 2149 PQ-YREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQ 2207
            PQ    ++            Q+   +QQ+   SAG+             + P G P A  
Sbjct: 949  PQRTSNVMITSNTTAPNWASQEGTSKQQEALTSAGV-------------RFPTGTPAAYT 995

Query: 2208 QQQRMQQHLPLQGSSMGQM--------AAQMGQLGQMGQPGLGADSTPNIQQALQQRILQ 2259
              Q +QQ +  Q  S   +        A QM  + QM Q   G    P     L+   L+
Sbjct: 996  PNQSLQQAVGSQQFSQRAVAPPNQLTPAVQMRPMNQMSQTLNGQTMGP-----LRGLNLR 1050

Query: 2260 QQQMKQQI 2267
              Q+  QI
Sbjct: 1051 PNQLSTQI 1058



 Score = 37.4 bits (85), Expect = 0.18
 Identities = 74/381 (19%), Positives = 115/381 (30%), Gaps = 44/381 (11%)

Query: 655  PVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQ 714
            P +PQ+Q         S  +   Q          ++    Q  +     +   P N S  
Sbjct: 405  PSVPQSQAQPQTGSGASRALPSWQEVSHAQQLKQIAANRQQHARMQQHQQQHQPTNWSAL 464

Query: 715  MNSMGSVPG--------------MAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQ 760
             +S G  PG                 SP   P P    G+  + +MA    ++       
Sbjct: 465  PSSAGPSPGPFGQEKIPSPSFGQQTFSPQSSPMPGVAGGSGQSKVMANYMYKAG------ 518

Query: 761  FPSSSGA-MSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGP-QASQLPCPPVTQSPLHPT 818
             PS+ G  + V M Q P     S        + NP   + P Q +  P         +  
Sbjct: 519  -PSAQGGHLDVLMQQKPQDLSRS-------FINNPHPAMEPRQGNTKPLFHFNSDQANQQ 570

Query: 819  PPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTP 878
             P    +   PSL H T       Q     Q         Q          S+   Q   
Sbjct: 571  MPSVLPSQNKPSLLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQ 630

Query: 879  TVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQP----PGTPLSQAAASIDNRV 934
              Q++  AQ   Q Q   Q       Q  QQQ     +QP    P  PL ++   +  ++
Sbjct: 631  QQQSSISAQQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKL 690

Query: 935  ------PTPSSVASAETNSQQPGPDVPVLEMKTETQAED---TEPDPGESKGEPRSEMME 985
                    P +    + + QQ      V+   T         + P+ G      +  ++ 
Sbjct: 691  LLQQMQNQPIAGMGYQVSQQQRQDQHSVVGQNTGPSPSPNPCSNPNTGSGYMNSQQSLLN 750

Query: 986  EDLQGASQVKEETDIAEQKSE 1006
            + L G  Q  +   I EQK +
Sbjct: 751  QQLMGKKQTLQR-QIMEQKQQ 770



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 34/150 (22%), Positives = 57/150 (38%), Gaps = 6/150 (4%)

Query: 793  NPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPST 852
            NP  +L  Q + +   P T  P +     A+  AG         P +T    + P Q ++
Sbjct: 895  NPKQLLANQNNPMMPRPPTLGPSNNNNV-ATFGAGSVGNSQQLRPNLTHSMASMPPQRTS 953

Query: 853  PVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQ--PPSVATPQSSQQQ 910
             V  +  T  P   S    ++ Q   T         TP   TP Q    +V + Q SQ+ 
Sbjct: 954  NVMITSNTTAPNWASQEGTSKQQEALTSAGVRFPTGTPAAYTPNQSLQQAVGSQQFSQRA 1013

Query: 911  PTPVHAQPPGT---PLSQAAASIDNRVPTP 937
              P +   P     P++Q + +++ +   P
Sbjct: 1014 VAPPNQLTPAVQMRPMNQMSQTLNGQTMGP 1043


>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
          Length = 788

 Score = 85.9 bits (211), Expect = 4e-16
 Identities = 127/447 (28%), Positives = 171/447 (38%), Gaps = 86/447 (19%)

Query: 1993 PMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNIL 2052
            P  G  + +  M +  A+  P   S QPP   S  A   +   + S ++PQ Q Q+  + 
Sbjct: 102  PPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSM--AVVSTATPQTQLQLQQVA 159

Query: 2053 KSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVP 2112
                Q    F +Q+ A     Q   Q Q     Q  MQ Q               QA   
Sbjct: 160  LQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQ--------------FQA--- 202

Query: 2113 RPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQ 2172
               V  QQQ +     Q Q L  +   H+ N   +  Q +++ R   LQ QQQQQQQQQQ
Sbjct: 203  ---VVQQQQQLQQQQQQQQHLIKL---HHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQ 256

Query: 2173 QQQQQQGSAGMAGGMAGHGQFQQPQGP--GGYPPAMQQQQRMQQH--------------- 2215
            QQQQQQ  A  A         QQPQ P     P  +QQ    Q H               
Sbjct: 257  QQQQQQ--ALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQ 314

Query: 2216 ---LPLQGSSMGQMAAQMGQLGQM--GQPGLGADSTPNI--QQALQQRILQQQQMKQ--- 2265
               LP Q  +   ++      GQM   QP L     P +  Q  +Q ++ QQQ   Q   
Sbjct: 315  PSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQ 374

Query: 2266 --QIGSPG-------------QPNPMSPQQHMLSGQPQAS----HLPGQQIATSLSNQVR 2306
              Q+ +PG                   P    +S  P +S      P  Q++ S    + 
Sbjct: 375  AAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLS 434

Query: 2307 SPAPVQSPR-PQSQPPHSSPSPRIQP-QPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGN 2364
            SP+P Q  + PQS PP   PSP  QP QPS    S  +  P P  +  + S   Q     
Sbjct: 435  SPSPGQQVQTPQSMPPPPQPSP--QPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQ----- 487

Query: 2365 PEQS---AMLPQ-LNTPSRSALSSELS 2387
            P QS   A  PQ  + PS   L++ ++
Sbjct: 488  PSQSPVTARTPQNFSVPSPGPLNTPVN 514



 Score = 76.3 bits (186), Expect = 3e-13
 Identities = 125/487 (25%), Positives = 172/487 (35%), Gaps = 73/487 (14%)

Query: 1945 PGRT--GMGTPGSQMAPVSLNVPRPNQVSGPVMPSM---------PPGQWQQAPLPQQQP 1993
            PG++  GMG+ G+   P+SL+   P   SG    SM            Q QQ  L QQQ 
Sbjct: 106  PGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQ- 164

Query: 1994 MPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTL--KSPSSPQQQQQVLNI 2051
                 +     Q QAA+   +    Q       SA+Q   + +  +     QQQQQ  ++
Sbjct: 165  ----QQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHL 220

Query: 2052 LKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGV 2111
            +K + Q      +Q+       Q  +Q Q   Q Q   Q Q  +  QP +Q     Q  +
Sbjct: 221  IKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQ-----QPPM 275

Query: 2112 PRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQ 2171
             +P  PP Q       PQ          H P      P               Q Q  Q 
Sbjct: 276  QQPQPPPSQAL-----PQQLQQMHHTQHHQPPPQPQQPPV------------AQNQPSQL 318

Query: 2172 QQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMG 2231
              Q Q Q     A  + G   + QP       P + QQ  +Q  +  Q     Q A Q  
Sbjct: 319  PPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQ-----QTAVQTA 373

Query: 2232 QLGQMGQPGLGADSTPNIQQALQQRI-LQQQQMKQQIGSPGQPNPMSPQ-QHMLSGQPQ- 2288
            Q  QM  PG+   +    Q  +  R           I S   P    P  Q   S  P  
Sbjct: 374  QAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPML 433

Query: 2289 ASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQ--PQPSPHHVSPQTGSPH 2346
            +S  PGQQ+ T      +S  P   P PQ   P S P+  +   P PSP    P + SP 
Sbjct: 434  SSPSPGQQVQTP-----QSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLP-SPSPQ 487

Query: 2347 PGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSALSSELSLVGDTTGD---------TL 2397
            P  +   A +     + +P        LNTP     SS +S  G +  +          L
Sbjct: 488  PSQSPVTARTPQNFSVPSP------GPLNTPVNP--SSVMSPAGSSQAEEQQYLDKLKQL 539

Query: 2398 EKFVEGL 2404
             K++E L
Sbjct: 540  SKYIEPL 546



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 77/263 (29%), Positives = 104/263 (39%), Gaps = 39/263 (14%)

Query: 1811 KLRQQQIQHRLQQAQLMRRRMATMNTRNVP-QQSLPSPTSAPPGTPTQQPSTPQTPQPPA 1869
            +L+QQQ Q + QQ Q  +   A    +  P QQ  P P+ A P    QQ    Q  QPP 
Sbjct: 245  QLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALP-QQLQQMHHTQHHQPPP 303

Query: 1870 QPQPSPVSMS-PAGFPSVARTQPPTT---------VSTGKPTSQVPAP----PPPAQP-- 1913
            QPQ  PV+ + P+  P  ++TQP  +         + T  P   V AP     PP QP  
Sbjct: 304  QPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQV 363

Query: 1914 --PPAAVEAARQIEREAQQQQHLYR------VNINNSMPPGRTGMGTPGSQMAPVSLNVP 1965
                 AV+ A+  +  A   Q +        ++I    PP       P S +      + 
Sbjct: 364  QQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMA 423

Query: 1966 RPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSIS 2025
            + +Q S P++ S  PG  QQ   PQ  P P  P P            P  PS QP  ++S
Sbjct: 424  QVSQSSLPMLSSPSPG--QQVQTPQSMPPPPQPSP-----------QPGQPSSQPNSNVS 470

Query: 2026 PSALQDLLRTLKSPSSPQQQQQV 2048
                      L SPS    Q  V
Sbjct: 471  SGPAPSPSSFLPSPSPQPSQSPV 493



 Score = 62.4 bits (150), Expect = 5e-09
 Identities = 86/310 (27%), Positives = 124/310 (40%), Gaps = 50/310 (16%)

Query: 622 KIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPV-------------RPPNG 668
           ++Q++ +++++ +  +Q  L  QP +  P  Q P  P +Q +             +PP  
Sbjct: 245 QLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQ 304

Query: 669 PLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISP 728
           P   PV + Q SQ      P S     + QA   P     M ++         P +   P
Sbjct: 305 PQQPPVAQNQPSQ----LPPQSQTQPLVSQAQALP---GQMLYTQPPLKFVRAPMVVQQP 357

Query: 729 SRMPQPPNMMGAHTNNMMAQAPAQS-QFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVP 787
              PQ      A      AQ  A   Q + +     + G M +    PP  T VS   +P
Sbjct: 358 PVQPQVQQQQTAVQTAQAAQMVAPGVQMITE---ALAQGGMHIRARFPPT-TAVS--AIP 411

Query: 788 GAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGM-TPPQPA- 845
            +++P     LG Q    P   V+QS L     P+      P  Q  TP  M  PPQP+ 
Sbjct: 412 SSSIP-----LGRQ----PMAQVSQSSLPMLSSPS------PGQQVQTPQSMPPPPQPSP 456

Query: 846 APTQPST-PVSSSGQTPTPTPGS-VPS-ATQTQSTPTVQAAAQAQVTPQP---QTPVQPP 899
            P QPS+ P S+    P P+P S +PS + Q   +P      Q    P P    TPV P 
Sbjct: 457 QPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPS 516

Query: 900 SVATPQSSQQ 909
           SV +P  S Q
Sbjct: 517 SVMSPAGSSQ 526



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 97/420 (23%), Positives = 152/420 (36%), Gaps = 43/420 (10%)

Query: 595 AKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRL-HKQGILGNQPALPAPGAQ 653
           +K +E  ++  A +RDEY  L+A  I   +    +K ++ +      L +    PA GA 
Sbjct: 38  SKDMESHVFLKAKTRDEYLSLVARLIIHFRDIHNKKSQASVSDPMNALQSLTGGPAAGAA 97

Query: 654 PPVIPQAQPVRPPNG---------PLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPR 704
              +P   P +   G         P+SL       + GM + + M++ +   PQ  +  +
Sbjct: 98  GIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGM-APHSMAVVSTATPQTQLQLQ 156

Query: 705 AASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPA---QSQFLPQNQF 761
             + +    Q          A+   +  Q      A  + M  Q  A   Q Q L Q Q 
Sbjct: 157 QVA-LQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQ 215

Query: 762 PSS-------SGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSP 814
                          +   Q   Q  ++Q Q+              Q +    PP+ Q P
Sbjct: 216 QQQHLIKLHHQNQQQIQQQQQQLQR-IAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPP 274

Query: 815 L-HPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQ 873
           +  P PPP+          H T     PPQ   P QP    +   Q P P   + P  +Q
Sbjct: 275 MQQPQPPPSQALPQQLQQMHHTQHHQPPPQ---PQQPPVAQNQPSQLP-PQSQTQPLVSQ 330

Query: 874 TQSTP-----------TVQAAAQAQVTP-QPQTPVQPPSVATPQSSQQQPTPVHAQPPGT 921
            Q+ P            V+A    Q  P QPQ   Q  +V T Q++Q     V  Q    
Sbjct: 331 AQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGV--QMITE 388

Query: 922 PLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRS 981
            L+Q    I  R P P++  SA  +S  P    P+ ++   +    + P PG+    P+S
Sbjct: 389 ALAQGGMHIRARFP-PTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQS 447



 Score = 57.4 bits (137), Expect = 2e-07
 Identities = 106/432 (24%), Positives = 148/432 (34%), Gaps = 112/432 (25%)

Query: 1916 AAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVM 1975
            A V+  +Q++++ QQQQHL +++  N              Q+      + R  Q+     
Sbjct: 202  AVVQQQQQLQQQQQQQQHLIKLHHQNQ------------QQIQQQQQQLQRIAQL----- 244

Query: 1976 PSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSIS-PSALQDLLR 2034
              +   Q QQ    QQQ          ++QAQ  +  P M   QPP S + P  LQ +  
Sbjct: 245  -QLQQQQQQQQQQQQQQQQ--------ALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHH 295

Query: 2035 TLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPG 2094
            T      PQ QQ    + ++ P  +               P  Q QP L SQ    P   
Sbjct: 296  TQHHQPPPQPQQP--PVAQNQPSQL--------------PPQSQTQP-LVSQAQALPGQM 338

Query: 2095 MHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREM 2154
            ++ QP L+ + A    V +P V PQ Q         QA  ++ PG             +M
Sbjct: 339  LYTQPPLKFVRAPMV-VQQPPVQPQVQQQQTAVQTAQAAQMVAPG------------VQM 385

Query: 2155 LRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQ 2214
            +   L Q                       GGM    +F         PP          
Sbjct: 386  ITEALAQ-----------------------GGMHIRARF---------PPTTAVSAIPSS 413

Query: 2215 HLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPN 2274
             +PL    M Q++     L  +  P  G                QQ Q  Q +  P QP 
Sbjct: 414  SIPLGRQPMAQVS--QSSLPMLSSPSPG----------------QQVQTPQSMPPPPQP- 454

Query: 2275 PMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPH-SSPSPRIQPQP 2333
              SPQ    S QP ++   G   + S      SP P QSP     P + S PSP     P
Sbjct: 455  --SPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTP 512

Query: 2334 -SPHHVSPQTGS 2344
             +P  V    GS
Sbjct: 513  VNPSSVMSPAGS 524



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 36/83 (43%), Positives = 45/83 (54%), Gaps = 16/83 (19%)

Query: 1839 VPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTG 1898
            V Q SLP  +S  PG   QQ  TPQ+  PP QP P P      G PS   +QP + VS+G
Sbjct: 425  VSQSSLPMLSSPSPG---QQVQTPQSMPPPPQPSPQP------GQPS---SQPNSNVSSG 472

Query: 1899 ---KPTSQVPAP-PPPAQPPPAA 1917
                P+S +P+P P P+Q P  A
Sbjct: 473  PAPSPSSFLPSPSPQPSQSPVTA 495



 Score = 42.4 bits (98), Expect = 0.006
 Identities = 32/96 (33%), Positives = 47/96 (48%), Gaps = 8/96 (8%)

Query: 1840 PQQSLPSPTSAP-PGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTG 1898
            PQ   P P  +P PG P+ QP++       + P PSP S  P+  PS   +Q P T  T 
Sbjct: 445  PQSMPPPPQPSPQPGQPSSQPNS----NVSSGPAPSPSSFLPS--PSPQPSQSPVTARTP 498

Query: 1899 KPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHL 1934
            +  S VP+P P   P   +   +     +A++QQ+L
Sbjct: 499  QNFS-VPSPGPLNTPVNPSSVMSPAGSSQAEEQQYL 533



 Score = 38.1 bits (87), Expect = 0.11
 Identities = 56/271 (20%), Positives = 82/271 (30%), Gaps = 22/271 (8%)

Query: 252 GHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASKQSMVNSLPTFP 311
           G AG+     G    +G  G+    GQP S +G  P G +G+ P   S   +  + P   
Sbjct: 95  GAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPH--SMAVVSTATPQTQ 152

Query: 312 TDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVLLLHAHKCQRRE 371
             ++  ++       Q Q        Q          + ++   QQ    +   + Q ++
Sbjct: 153 LQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQ 212

Query: 372 QANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQAILGSPASGIQNTIGSVGTGQQNATS 431
           Q   +     L H        N     Q  +  Q I        Q         QQ A  
Sbjct: 213 QQQQQQHLIKLHH-------QNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQ 265

Query: 432 LSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPM 491
              P    P    +   +  LP   Q     Q   P  QP QP   Q         N P 
Sbjct: 266 AQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQ---------NQPS 316

Query: 492 NIPAGGITTDQQPPNLISESALPTSLGATNP 522
            +P       Q  P +    ALP  +  T P
Sbjct: 317 QLP----PQSQTQPLVSQAQALPGQMLYTQP 343



 Score = 35.8 bits (81), Expect = 0.52
 Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 11/56 (19%)

Query: 1838 NVPQQSLPSPTS---APPGTPTQQPSTPQTPQPPAQPQPSPVS--------MSPAG 1882
            NV     PSP+S   +P   P+Q P T +TPQ  + P P P++        MSPAG
Sbjct: 468  NVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAG 523



 Score = 32.7 bits (73), Expect = 4.4
 Identities = 31/122 (25%), Positives = 51/122 (41%), Gaps = 3/122 (2%)

Query: 89  VSASSPVQQGLGGQAQGQPNSANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPT--PA 146
           VSA       LG Q   Q + +++  LS+       Q   S P  P+ +     P+  P 
Sbjct: 407 VSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPN 466

Query: 147 ASQALNPQAQKQVGLATSSPATSQTGPGICMNANFNQTHPGLLNSN-SGHSLINQASQGQ 205
           ++ +  P       L + SP  SQ+        NF+   PG LN+  +  S+++ A   Q
Sbjct: 467 SNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQ 526

Query: 206 AQ 207
           A+
Sbjct: 527 AE 528


>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
            1 [Homo sapiens]
          Length = 1250

 Score = 84.7 bits (208), Expect = 1e-15
 Identities = 106/429 (24%), Positives = 139/429 (32%), Gaps = 63/429 (14%)

Query: 643  NQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPM--------SLGNV 694
            +QP+ P P   PP  P   P  PP  PL       Q +    S  PM         L N 
Sbjct: 622  SQPSPPLPPPPPPPPPPPPPPPPPPPPLP-----SQSAPSAGSAAPMFVKYSTITRLQNA 676

Query: 695  QLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQ 754
                  +      P+  S  +     VP   + P   P PP          +  AP    
Sbjct: 677  SQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPS 736

Query: 755  FLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQ-VPGAALPNPLNMLGPQASQLPCPPVTQS 813
             LPQ                PP    + Q Q +   A P P     P    +P P   Q+
Sbjct: 737  -LPQ-------------FSAPPPPLKIHQVQHITQVAPPTP-----PPPPPIPAPLPPQA 777

Query: 814  PLHPT---PPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPS 870
            P  P    P P ST    P +    PP  TPP P A  QP+ P S    +P   P  VP 
Sbjct: 778  PPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPP 837

Query: 871  ATQTQS--------------TPTVQAAAQAQVTPQPQTPV---QPPSVATPQSSQQQPTP 913
             T  +                P+V     +Q  P P  P    QP        + Q P  
Sbjct: 838  PTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPA 897

Query: 914  VHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPG 973
            V A+P   P S    S D   P P S          P P  P     T +   D    PG
Sbjct: 898  VKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPG 957

Query: 974  ESKGE---PRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSN 1030
            +   +   P  +      Q  S +K  +    +  EP     K+P V   V +    + +
Sbjct: 958  KKTSKTSSPGGKKPPPTPQRNSSIKSSS--GAEHPEP-----KRPSVDSLVSKFTPPAES 1010

Query: 1031 GTASQSTSP 1039
            G+ S+ T P
Sbjct: 1011 GSPSKETLP 1019



 Score = 64.7 bits (156), Expect = 1e-09
 Identities = 64/277 (23%), Positives = 97/277 (35%), Gaps = 28/277 (10%)

Query: 644  QPALPAPGAQPPVIPQAQPVRPPNGPLSLPV--NRMQVSQGMNSFNPMSLGNVQLPQAPM 701
            Q A P P   PP+     P  PP   +++P   +   V+  +    P +      P  P+
Sbjct: 757  QVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPT------PTPPV 810

Query: 702  GPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPA-----QSQFL 756
             P    P   +  +      P + + P  +P+  +       + ++  P+      SQF 
Sbjct: 811  PPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFP 870

Query: 757  PQNQFPSSSGA------MSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPV 810
            P    P+           +V    PPA     + Q     +P+P     P  S L  PP 
Sbjct: 871  PPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPP 930

Query: 811  TQSPLH-PTPPPASTAAGMPS--------LQHTTPPGMTPPQPAAPTQPSTPVSSSGQTP 861
              SP+  P PPP  TA+  P            T+ PG   P P      S   SS  + P
Sbjct: 931  PPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHP 990

Query: 862  TPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQP 898
             P   SV S     + P    +   +  P P  P +P
Sbjct: 991  EPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKP 1027



 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 79/334 (23%), Positives = 112/334 (33%), Gaps = 81/334 (24%)

Query: 1840 PQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSV------------- 1886
            PQ  + +P +A   +P   P  P  P PP  P P P  +     PS              
Sbjct: 611  PQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTI 670

Query: 1887 -----------ARTQPPT----TVSTGKPTSQVP-----APPPPAQPPPAAVEAARQIER 1926
                       A  +PPT       + KP   VP      PPPP  PPP    A  Q++ 
Sbjct: 671  TRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLK- 729

Query: 1927 EAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQA 1986
                              P       P     P  L + +   ++    P+ PP     A
Sbjct: 730  ------------------PAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPA 771

Query: 1987 PLPQQQPMPGLPRPVISMQA------------QAAVAGPRMP----SVQP--PRSISPSA 2028
            PLP Q P    P+P++++ A            QAA   P  P      QP  P S  P +
Sbjct: 772  PLPPQAP----PKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPS 827

Query: 2029 LQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKY--VANQPGMQPQPGLQSQ 2086
                   +  P+ P+QQ        S    + + +KQ  +++      P M+ QP     
Sbjct: 828  PPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVP 887

Query: 2087 PGMQPQ--PGMHQQPSLQNLNAMQAGVPRPGVPP 2118
              + PQ  P +  +P  Q        VP P  PP
Sbjct: 888  ANVAPQSPPAVKAKPKWQ---PSSIPVPSPDFPP 918



 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 73/303 (24%), Positives = 99/303 (32%), Gaps = 63/303 (20%)

Query: 1840 PQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQP---QPS-PVSMSPAGFPSVARTQPPTTV 1895
            P  ++P+PTS     P    + P TP PP  P   QP+ P S  P   P+     PP T+
Sbjct: 781  PLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTL 840

Query: 1896 STGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGS 1955
               +     P PP P  P P+ V+                   I +  PP  T       
Sbjct: 841  PKQQSFCAKP-PPSPLSPVPSVVK------------------QIASQFPPPPTPPAMESQ 881

Query: 1956 QMAPVSLNV---------------PRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRP 2000
             + PV  NV               P    V  P  P  PP      P P   P+P  P P
Sbjct: 882  PLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPP 941

Query: 2001 VISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRT---LKSPSSPQQQQQVLNIL-KSNP 2056
                        P   S  P +S SP        +    K P +PQ+   + +     +P
Sbjct: 942  -----------PPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHP 990

Query: 2057 QLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGV 2116
            +     +    +K+        P       P   P+PG         LN   +GV  PGV
Sbjct: 991  EPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPG--------KLNL--SGVNLPGV 1040

Query: 2117 PPQ 2119
              Q
Sbjct: 1041 LQQ 1043



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 77/317 (24%), Positives = 102/317 (32%), Gaps = 41/317 (12%)

Query: 1825 QLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFP 1884
            QL     A M + N P  SL  P S  P   T  P T   P PP  P P P    P    
Sbjct: 586  QLEESSKARMESMNRPYTSLVPPLSPQPKIVT--PYTASQPSPPLPPPPPPPPPPP---- 639

Query: 1885 SVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAA------RQIEREAQQQQHLYRVN 1938
                           P    P PP P+Q  P+A  AA        I R     QH   + 
Sbjct: 640  ---------------PPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGAL- 683

Query: 1939 INNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLP 1998
                 PP           + P +  VP P     P  P     Q + AP     P    P
Sbjct: 684  FKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAP 743

Query: 1999 RP---VISMQAQAAVAGPRMPSVQP-PRSISPSALQDLLRTLKSPSSPQQQQQVL-NILK 2053
             P   +  +Q    VA P  P   P P  + P A    L T+ +P+S +    V+     
Sbjct: 744  PPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAP 803

Query: 2054 SNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQ--------PGMHQQPSLQNLN 2105
              P       K++ A   +  P   P P +   P   P+        P     P    + 
Sbjct: 804  PTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVK 863

Query: 2106 AMQAGVPRPGVPPQQQA 2122
             + +  P P  PP  ++
Sbjct: 864  QIASQFPPPPTPPAMES 880



 Score = 56.2 bits (134), Expect = 4e-07
 Identities = 69/290 (23%), Positives = 112/290 (38%), Gaps = 53/290 (18%)

Query: 1838 NVPQQSLPSPTSAPPGTPTQQP-STPQTPQPPAQ-------PQPSPVSMSPAGFPSVART 1889
            NV  QS P+  + P   P+  P  +P  P PP +       P PSPV   P   P  A  
Sbjct: 889  NVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASP 948

Query: 1890 QPPTTVSTGKPTSQVPAP----PPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPP 1945
             P  + S GK TS+  +P    PPP     ++++++   E    ++  +  + ++   PP
Sbjct: 949  TPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSL-VSKFTPP 1007

Query: 1946 GRTGMGTPGSQMAPVSLNVPRPNQ--VSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVIS 2003
              +  G+P  +  P     P+P +  +SG  +P +            QQ       PV+S
Sbjct: 1008 AES--GSPSKETLPPPAAPPKPGKLNLSGVNLPGV-----------LQQGCVSAKAPVLS 1054

Query: 2004 MQAQ-AAVAGPRMPS-----VQPPRSISPSALQDLLRTLKSPSSPQ--------QQQQVL 2049
             + + + V  P  PS       PP +  P    ++       +SP+        QQ   +
Sbjct: 1055 GRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKM 1114

Query: 2050 NILKSNPQ-----------LMAAFIKQRTAKYVANQPGMQPQPGLQSQPG 2088
            ++ K+ P              A   +Q T   V  Q    P+  L  QPG
Sbjct: 1115 SVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPG 1164



 Score = 51.6 bits (122), Expect = 9e-06
 Identities = 82/356 (23%), Positives = 105/356 (29%), Gaps = 79/356 (22%)

Query: 760  QFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTP 819
            Q   SS A    M +P           P    P   +   P     P PP    P  P P
Sbjct: 586  QLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPP 645

Query: 820  PPASTAAGMPSL--------------------QHT-------TPPGM----------TPP 842
            PP   +   PS                     QH+       TPP M           PP
Sbjct: 646  PPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPP 705

Query: 843  QPAAPTQPSTPVSSSGQTPTPTPGS----------VPSATQTQSTPTVQAAAQAQVTPQ- 891
                P  P  P       P PTPGS           PS  Q  + P      Q Q   Q 
Sbjct: 706  NGVVPPPPPPP-------PPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQV 758

Query: 892  -PQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQ-- 948
             P TP  PP +  P   Q  P P+   P  T     A  +    P   +        Q  
Sbjct: 759  APPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPA 818

Query: 949  ------QPGPDVPVLEMKTET----QAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEET 998
                   P P  P + +   T    Q+   +P P      P S +     Q ASQ     
Sbjct: 819  FPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPP-----SPLSPVPSVVKQIASQFPPPP 873

Query: 999  DIAEQKSEPME-----VDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKP 1049
                 +S+P++     V  + P   V+ K + + SS    S    P  P   +  P
Sbjct: 874  TPPAMESQPLKPVPANVAPQSPPA-VKAKPKWQPSSIPVPSPDFPPPPPESSLVFP 928



 Score = 48.9 bits (115), Expect = 6e-05
 Identities = 65/315 (20%), Positives = 97/315 (30%), Gaps = 39/315 (12%)

Query: 1821 LQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSP 1880
            + Q+Q ++ ++       VP    P P   P     Q    P  P  P    P P  +  
Sbjct: 691  VMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPP-PLKI 749

Query: 1881 AGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNIN 1940
                 + +  PPT      P   +PAP PP  PP   V         A          + 
Sbjct: 750  HQVQHITQVAPPTP----PPPPPIPAPLPPQAPPKPLVTI------PAPTSTKTVAPVVT 799

Query: 1941 NSMPPGRTGMGTPGSQMA--PVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLP 1998
             + PP  T    P  +    P S   P P     PV P   P Q      P   P+  +P
Sbjct: 800  QAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVP 859

Query: 1999 RPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQL 2058
              V  + +Q            PP    P+     L+ + +  +PQ    V    K+ P+ 
Sbjct: 860  SVVKQIASQF-----------PPPPTPPAMESQPLKPVPANVAPQSPPAV----KAKPKW 904

Query: 2059 MAAFI-----------KQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAM 2107
              + I            + +  +    P   P P     P   P P     P  +     
Sbjct: 905  QPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTS 964

Query: 2108 QAGVPRPGVPPQQQA 2122
              G  +P   PQ+ +
Sbjct: 965  SPGGKKPPPTPQRNS 979



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 70/293 (23%), Positives = 98/293 (33%), Gaps = 40/293 (13%)

Query: 643  NQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVS----QGMNSFNPMSLGNVQLPQ 698
            +QP  P P    P  P A   +P   P S+PV          +    F P     V  P 
Sbjct: 880  SQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPP 939

Query: 699  APMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQ 758
             P  P A+   + S    S G       SP     PP       +++ + + A+    P+
Sbjct: 940  PPPPPTASPTPDKS---GSPGKKTSKTSSPGGKKPPPTPQ--RNSSIKSSSGAEH---PE 991

Query: 759  NQFPSSSGAMSVGMGQPPAQTGVSQGQV--PGAALPNP--LNMLG---PQASQLPC---- 807
             + PS    +S     PPA++G    +   P AA P P  LN+ G   P   Q  C    
Sbjct: 992  PKRPSVDSLVS--KFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAK 1049

Query: 808  ---------PPVTQSPLHPT-----PPPASTAAGMPSLQHTTP-PGMTPPQPAAPTQPST 852
                       V + P  P+     PPP  T   +P ++      G T P+ A       
Sbjct: 1050 APVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQ 1109

Query: 853  PVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQ 905
              S       P P        T+ T    +      T  PQ P  P S  + Q
Sbjct: 1110 QWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQ 1162



 Score = 36.2 bits (82), Expect = 0.40
 Identities = 30/126 (23%), Positives = 48/126 (38%), Gaps = 5/126 (3%)

Query: 2265 QQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQ--SQPPH 2322
            +QI S   P P  P       +P  +++  Q      +     P+ +  P P     PP 
Sbjct: 863  KQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPE 922

Query: 2323 SS---PSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSR 2379
            SS   P P   P P+P    P T SP P  + +      +      ++    PQ N+  +
Sbjct: 923  SSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIK 982

Query: 2380 SALSSE 2385
            S+  +E
Sbjct: 983  SSSGAE 988


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 98/345 (28%), Positives = 130/345 (37%), Gaps = 60/345 (17%)

Query: 646 ALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRA 705
           A P+P A PP+ P A P   P  P +L V+ +Q       F+P     VQ   AP  P A
Sbjct: 632 APPSPPASPPLSPLATP--SPQAPNALAVHLLQAP-----FSPPPSPPVQ---APFSPPA 681

Query: 706 ASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSS 765
           + P++ S    S    P +A  P ++P  P           A  P      P  Q P   
Sbjct: 682 SPPVSPSATPPSQAP-PSLAAPPLQVPPSPP----------ASPPMSPSATPPPQAPPPL 730

Query: 766 GAMSVGMG-QPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVT--QSPLHPTPPPA 822
            A  + +   PPA   +S    P   +P PL +  P     P PP +   SPL   PP A
Sbjct: 731 AAPPLQVPPSPPASPPMSPSATPPPRVP-PL-LAAPPLQVPPSPPASLPMSPLAKPPPQA 788

Query: 823 STAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPS---ATQTQSTPT 879
             A   P LQ                 PS P S  GQ P     S+P    AT     P 
Sbjct: 789 PPALATPPLQ---------------ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 833

Query: 880 VQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSS 939
           V AA      P  Q P  PP+  T Q+ ++ PTP     P T +S    ++    P P  
Sbjct: 834 VLAA------PLLQVPPSPPASPTLQAPRRPPTP----GPDTSVSGPRLTL-ALAPGPPP 882

Query: 940 VASAETNSQQPGPDV-----PVLEMKTETQAEDTEPDPGESKGEP 979
             S   +S   GPD+            E +  D+ P+ G +   P
Sbjct: 883 PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP 927



 Score = 78.6 bits (192), Expect = 7e-14
 Identities = 136/581 (23%), Positives = 198/581 (34%), Gaps = 90/581 (15%)

Query: 428 NATSLSNPNPIDPSSM--QRAYAALGLPYMNQPQTQLQPQV-PGQQPAQPQTHQQMRTLN 484
           +AT LS+P    PS+    RA A    P     Q    PQV P ++ A P        L 
Sbjct: 245 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAP-------ALG 297

Query: 485 PLGNNPMNIPA-GGITTDQQPPNLISESALPTSLGATNPLMN-------DGSNSGNIGTL 536
           PL ++P+  P+  G      PP   + + LP +L  + PL           S   ++ TL
Sbjct: 298 PLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTL 357

Query: 537 ----STIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQ-AIFPTPDPAALKDRRMENL 591
               +T P+ APPS T         +       + H L   ++   P P AL   +    
Sbjct: 358 PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTS 417

Query: 592 VAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPG 651
           +             + +    +  L     + Q  L    R          + P L AP 
Sbjct: 418 LG------------SPTLQATHSFLTMSPRQTQASLTSPSRPASTPP----DSPPLQAPL 461

Query: 652 AQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNH 711
           + P   P    + P   PLS P+  +   Q ++S    S      PQAP+      P+  
Sbjct: 462 SLPASPPLQTSLSPAVSPLSSPLT-IHPLQALSSLASHS------PQAPLSSLIMPPL-- 512

Query: 712 SVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVG 771
             +  S  + P +   P+ +  PP        N+ + AP   Q              S  
Sbjct: 513 --ETQSSLAPPSLQTPPASLTTPP------LENLPSLAPPPLQ------------TASAP 552

Query: 772 MGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSL 831
           +  P  +T       P  A P+PL    P+       P  Q+P     PP       P  
Sbjct: 553 LTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLS 612

Query: 832 QHTTPPGMTPPQPAAP--TQPSTPVSSSGQTPTPTPG-SVPSA-----TQTQSTPTVQAA 883
              TPP   PP  A P    P +P +S   +P  TP    P+A      Q   +P     
Sbjct: 613 PLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 672

Query: 884 AQAQVTPQPQTPVQP---PSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSV 940
            QA  +P    PV P   P    P S    P  V   PP +P    +A+   + P P + 
Sbjct: 673 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA 732

Query: 941 ASAE-----------TNSQQPGPDVPVLEMKTETQAEDTEP 970
              +           + S  P P VP L      Q   + P
Sbjct: 733 PPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPP 773



 Score = 71.2 bits (173), Expect = 1e-11
 Identities = 139/537 (25%), Positives = 196/537 (36%), Gaps = 110/537 (20%)

Query: 445 RAYAALGLPYMNQPQTQLQPQVPGQ-QPAQPQTHQQMRTLNP---LGNNPMNIPAGGITT 500
           +A AA   P    P   L P+ PG  +P  P T   +R L     +G  P+   AGGI  
Sbjct: 9   KAGAAARTPAARAPGL-LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGI-- 65

Query: 501 DQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQ 560
                     + +P S     P  + G++S N       P + PP+S    +G      +
Sbjct: 66  --------GGATIPESAPRAGPTRSAGTSSRN-------PASRPPASG---RGERAPPAK 107

Query: 561 DLRSHLVHKLVQAIFPT-PDPAALKDRRM--ENLVAYAKKVEGDMYE--SANSRDEYYHL 615
           +     V    +A   T P P   K  R+  E  VA  K  E       SA +R +    
Sbjct: 108 NTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRD---- 163

Query: 616 LAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVN 675
                          RRSR       G +  LP P       P A+P  P  GP     +
Sbjct: 164 -TSGPTPGTPSPAMARRSRA-----AGTEVGLPRPA------PSARPRPPTEGPRKSVSS 211

Query: 676 RMQVSQGMNS----FNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRM 731
             + S    S      P + G +Q P +     +A+P++                SP+R 
Sbjct: 212 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS----------------SPAR- 254

Query: 732 PQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAAL 791
              P+  G        +APA     P    P    A+     +PP  T   +   P    
Sbjct: 255 -SGPSARGT------PRAPAH----PSQPKPKGLQAL-----RPPQVTPPRKDAAPA--- 295

Query: 792 PNPLNMLGP-QASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQP 850
                 LGP  +S L  P  + +   P PPP + A  +P+    +PP +  P P AP  P
Sbjct: 296 ------LGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPP-LATPLPLAPPSP 348

Query: 851 STPVSSSGQTPTPTPGSVPS-ATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQ 909
           S P S   QT    P + PS A  + +TP +QA    Q  P    P+Q P   T  S Q 
Sbjct: 349 SAPPSL--QTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIP----PIQVPHSLTSPSLQA 402

Query: 910 QPTPV------HAQPPGTPLSQAAASIDNRVP--TPSSVASAETNSQQPGPDVPVLE 958
            P+P+           G+P  QA  S     P  T +S+ S    +  P PD P L+
Sbjct: 403 PPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTP-PDSPPLQ 458



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 136/611 (22%), Positives = 201/611 (32%), Gaps = 127/611 (20%)

Query: 1835 NTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQ---- 1890
            + R  P+         P G    +P     P+  A P   P+S SP   PS + T+    
Sbjct: 258  SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPV 317

Query: 1891 -PPTTVSTGKPTSQVPAPP-----PPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMP 1944
             PP   +T  P +  P+PP     P A P P+A  + + +                 + P
Sbjct: 318  PPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPP-------------ATP 364

Query: 1945 PGRT--GMGTPGSQMAPVSLNVPR---PNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPR 1999
            P +    M TP  Q  P    +P    P+ ++ P + + P        L   Q    L  
Sbjct: 365  PSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPP----SPLALSSLQATTSLGS 420

Query: 2000 PVIS----------MQAQAAVAGPRMPSVQPPRS----------ISP---SALQDLLRTL 2036
            P +            Q QA++  P  P+  PP S           SP   ++L   +  L
Sbjct: 421  PTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPL 480

Query: 2037 KSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMH 2096
             SP +    Q + ++   +PQ   A +       +  Q  + P P LQ+ P     P + 
Sbjct: 481  SSPLTIHPLQALSSLASHSPQ---APLSSLIMPPLETQSSLAP-PSLQTPPASLTTPPLE 536

Query: 2097 QQPSL--QNLNAMQAGVPRPGV-PPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYRE 2153
              PSL    L    A +  P +  P   A   L      L    P    ++A+  PQ   
Sbjct: 537  NLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPP 596

Query: 2154 MLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQ 2213
             L    LQ                             G    P  P   PP   Q     
Sbjct: 597  ALASPPLQ-----------------------------GLPSPPLSPLATPP--PQAPPXL 625

Query: 2214 QHLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQ-------QQQMKQQ 2266
               PLQ       +  +  L         A  +P    AL   +LQ          ++  
Sbjct: 626  ALPPLQAPPSPPASPPLSPL---------ATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 676

Query: 2267 IGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSP--APVQSPRPQSQPPHSS 2324
               P  P P+SP     S  P +   P  Q+  S      SP  +P  +P PQ+ PP ++
Sbjct: 677  FSPPASP-PVSPSATPPSQAPPSLAAPPLQVPPS---PPASPPMSPSATPPPQAPPPLAA 732

Query: 2325 PSPRIQPQP-----------SPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQ 2373
            P  ++ P P            P  V P   +P   +  +  +S+    L  P   A  P 
Sbjct: 733  PPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAP-PA 791

Query: 2374 LNTPSRSALSS 2384
            L TP   AL S
Sbjct: 792  LATPPLQALPS 802



 Score = 65.9 bits (159), Expect = 5e-10
 Identities = 109/470 (23%), Positives = 154/470 (32%), Gaps = 59/470 (12%)

Query: 1831 MATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQP-PAQPQPSPVSMSPAGFPSVART 1889
            + T    N+P  + P   +A     T    TP  P P P Q  PSP++  P   PS   T
Sbjct: 530  LTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIAT 589

Query: 1890 QPPTT--VSTGKPTSQVPAPP--PPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPP 1945
             PP         P   +P+PP  P A PPP A         +A           +    P
Sbjct: 590  PPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPP---------SPPASP 640

Query: 1946 GRTGMGTPGSQMAPVSLNV---------PRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPG 1996
              + + TP  Q AP +L V         P    V  P  P   P     A  P Q P P 
Sbjct: 641  PLSPLATPSPQ-APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP-PS 698

Query: 1997 LPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNP 2056
            L  P + +      + P  PS  PP    P      L+   SP +              P
Sbjct: 699  LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVP 758

Query: 2057 QLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQP--QPGMHQQPSLQNLNAMQAGVPRP 2114
             L+AA             P +Q  P   +   M P  +P     P+L       A  P  
Sbjct: 759  PLLAA-------------PPLQVPPSPPASLPMSPLAKPPPQAPPAL-------ATPPLQ 798

Query: 2115 GVPPQQQAMGGLNPQGQALNI-MNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQ 2173
             +P    +  G  P   + ++ M+P     +A+  PQ   +L   LLQ           Q
Sbjct: 799  ALPSPPASFPGQAPFSPSASLPMSP-----LATPPPQAPPVLAAPLLQVPPSPPASPTLQ 853

Query: 2174 QQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQL 2233
              ++  + G    ++G  +      PG  PP  +          L G S    +      
Sbjct: 854  APRRPPTPGPDTSVSG-PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 912

Query: 2234 GQMGQP--GLGADSTPNIQQALQQRILQQQQMKQQI---GSPGQPNPMSP 2278
            G    P  G  A   P+ + A        +     +   G+PG P P  P
Sbjct: 913  GYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPP 962



 Score = 52.4 bits (124), Expect = 5e-06
 Identities = 131/536 (24%), Positives = 180/536 (33%), Gaps = 108/536 (20%)

Query: 1846 SPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVA---RTQPPT-----TVST 1897
            S  SA     T  P TP TP P A  + S  + +  G P  A   R +PPT     +VS+
Sbjct: 154  SALSAGARRDTSGP-TPGTPSP-AMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS 211

Query: 1898 GKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGM---GTP- 1953
                S    P P A+  P+A      ++R A +        +++   P R+G    GTP 
Sbjct: 212  ASEHSTTE-PSPAARRRPSA---GGGLQRPASRSLSSSATPLSS---PARSGPSARGTPR 264

Query: 1954 ----GSQMAPVSLNVPRPNQVSGPVMPSMPP-GQWQQAPLPQQQPMPGLPRPVISMQAQA 2008
                 SQ  P  L   RP QV+ P   + P  G    +PL    P     RPV       
Sbjct: 265  APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPV----PPP 320

Query: 2009 AVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTA 2068
              A   +P+  PP   SP     L     SPS+P   Q +                    
Sbjct: 321  DNAATPLPATLPP---SPPLATPLPLAPPSPSAPPSLQTL-------------------- 357

Query: 2069 KYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNP 2128
                  P     P  Q+ P M   P M   PSLQ +  +Q  VP     P  QA     P
Sbjct: 358  ------PSPPATPPSQAPPSMTTPP-MQAPPSLQTIPPIQ--VPHSLTSPSLQA----PP 404

Query: 2129 QGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMA 2188
               AL+ +             Q    L    LQ          +Q Q             
Sbjct: 405  SPLALSSL-------------QATTSLGSPTLQATHSFLTMSPRQTQ------------- 438

Query: 2189 GHGQFQQPQGPGGYP---PAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADS 2245
                   P  P   P   P +Q    +    PLQ S    ++     L       L + +
Sbjct: 439  --ASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLA 496

Query: 2246 TPNIQQALQQRILQQQQMKQQIGSPG-QPNPMSPQQHMLSGQPQASHLPGQQIATSLSN- 2303
            + + Q  L   I+   + +  +  P  Q  P S     L   P  +  P Q  +  L+  
Sbjct: 497  SHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTP 556

Query: 2304 -----QVRSPAPVQS-PRPQSQPPHSSPSPRIQPQPS--PHHVSPQ-TGSPHPGLA 2350
                    +P P+Q+ P P + PP  +PS    P P   P   SP   G P P L+
Sbjct: 557  HLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLS 612



 Score = 51.6 bits (122), Expect = 9e-06
 Identities = 84/348 (24%), Positives = 113/348 (32%), Gaps = 100/348 (28%)

Query: 648  PAPGAQPPVIPQAQPVR-------------PPNGPLSLPVNRMQVSQGMNSFNPMSLGNV 694
            P+P A PP+ P A P               PP+ P SLP++ +                 
Sbjct: 739  PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP------------- 785

Query: 695  QLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISP-SRMPQPPNMMGAHTNNMMAQAPAQS 753
              PQAP                     P +A  P   +P PP           A  P Q+
Sbjct: 786  --PQAP---------------------PALATPPLQALPSPP-----------ASFPGQA 811

Query: 754  QFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQS 813
             F P    P S       +  PP Q            L  PL  + P     P  P  Q+
Sbjct: 812  PFSPSASLPMSP------LATPPPQA--------PPVLAAPLLQVPPSP---PASPTLQA 854

Query: 814  PLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQ 873
            P  P  P   T+   P L     PG  PP   +P+   +    +G + + T  S P   +
Sbjct: 855  PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT--STPEELR 912

Query: 874  -TQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHA--QPPGTPLSQAAASI 930
               S P   AAA    +P P   +   +   P +  + P P  A    PG PL    A+ 
Sbjct: 913  GYDSGPEGGAAA----SPPPDAEL---AACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT- 964

Query: 931  DNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGE 978
                  P S     T  +  GP+           A D  P PG S G+
Sbjct: 965  -----GPGSADGLCTIYETEGPE----SATPAPGALDPGPSPGTSGGK 1003



 Score = 42.4 bits (98), Expect = 0.006
 Identities = 64/291 (21%), Positives = 100/291 (34%), Gaps = 24/291 (8%)

Query: 1854 TPTQQPSTPQTPQPPAQPQP----SPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPP 1909
            TP  +     TP+PP  P+P    +P ++   G       +P    + G   + +P   P
Sbjct: 16   TPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAP 75

Query: 1910 PAQPPPAAVEAARQ-IEREAQQQQHLYRVNINNSMP-----PGR----TGMGTPGSQMAP 1959
             A P  +A  ++R    R     +        N+ P     PGR    T  G  G +   
Sbjct: 76   RAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR 135

Query: 1960 VSL--NVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPS 2017
            +S    V R      P   ++  G    A      P PG P P ++ +++A  AG  +  
Sbjct: 136  ISAEETVARGKATEAPKRSALSAG----ARRDTSGPTPGTPSPAMARRSRA--AGTEVGL 189

Query: 2018 VQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGM 2077
             +P  S  P    +  R   S +S     +     +  P        QR A    +    
Sbjct: 190  PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL--QRPASRSLSSSAT 247

Query: 2078 QPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNP 2128
                  +S P  +  P     PS      +QA  P    PP++ A   L P
Sbjct: 248  PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP 298


>gi|34996489 pleckstrin homology domain interacting protein [Homo
            sapiens]
          Length = 1821

 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 53/155 (34%), Positives = 81/155 (52%), Gaps = 8/155 (5%)

Query: 1007 PMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELR--QALMPTLEALY 1064
            P+    KK  +     EE+++   GT+++     QPR+++    +    QA     E L 
Sbjct: 1270 PLYNSMKKKVLSDSEDEEKDADVPGTSTRKRKDHQPRRRLRNRAQSYDIQAWKKQCEELL 1329

Query: 1065 R---QDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWL 1121
                Q  +S PFRQPVD  LL  PDY DI+  PMD +T++  L+ G Y+ P +   DV L
Sbjct: 1330 NLIFQCEDSEPFRQPVD--LLEYPDYRDIIDTPMDFATVRETLEAGNYESPMELCKDVRL 1387

Query: 1122 MFNNAWLYN-RKTSRVYKFCSKLAEVFEQEIDPVM 1155
            +F+N+  Y   K SR+Y    +L+  FE+ I  V+
Sbjct: 1388 IFSNSKAYTPSKRSRIYSMSLRLSAFFEEHISSVL 1422



 Score = 33.1 bits (74), Expect = 3.4
 Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 2/66 (3%)

Query: 1073 FRQPVDPQLLGIPDYFDIVKNPMDLSTIKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRK 1132
            F  PVD Q    P Y  +V  P DLSTIK++L+   Y+     + +V  + +N   +N  
Sbjct: 1184 FVAPVDLQ--AYPMYCTVVAYPTDLSTIKQRLENRFYRRVSSLMWEVRYIEHNTRTFNEP 1241

Query: 1133 TSRVYK 1138
             S + K
Sbjct: 1242 GSPIVK 1247


>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
            sapiens]
          Length = 4911

 Score = 82.4 bits (202), Expect = 5e-15
 Identities = 157/622 (25%), Positives = 224/622 (36%), Gaps = 125/622 (20%)

Query: 1845 PSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVART----QPPTT--VSTG 1898
            PS   + PGT ++  S     QPP  P+P   S S +   + + T    QPP T   +T 
Sbjct: 2112 PSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTV 2171

Query: 1899 KPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPG--RTGMGTPGSQ 1956
             P SQ P  P P+      V      +R +    H          PPG  R G+  P SQ
Sbjct: 2172 DPYSQQPQTPRPSTQTDLFVTPVTN-QRHSDPYAH----------PPGTPRPGISVPYSQ 2220

Query: 1957 MAPVSLNVPRPNQVSGPVMPSM--PPGQWQQAPLPQ--QQPMPGLPRPVI-SMQAQAAVA 2011
                    PRP    G    SM  P     Q P  Q  Q   P LP P++      +   
Sbjct: 2221 PPA----TPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTP 2276

Query: 2012 GPRMPSVQPPRS-ISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKY 2070
             P  P +    S +SPSA +D     +SP +P+ Q               +F   +TA  
Sbjct: 2277 RPPGPGLSDTFSRVSPSAARDPYD--QSPMTPRSQSD-------------SFGTSQTAHD 2321

Query: 2071 VANQPGMQPQPGLQSQPGMQPQPGMHQQ-PSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQ 2129
            VA+    QP+PG +          MH Q      ++ +   VP  GV   Q  +      
Sbjct: 2322 VAD----QPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQNTVNMAQAD 2377

Query: 2130 GQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAG 2189
             + L                + R+ LR  +LQQQQQ++   +Q++  Q   A    G   
Sbjct: 2378 TEKL----------------RQRQKLREIILQQQQQKKIAGRQEKGSQDSPAVPHPGPLQ 2421

Query: 2190 HGQ-------FQQPQGP-------------------------GGYPPAMQQQQRMQQH-- 2215
            H Q       F +P  P                         G YPP +     M+ H  
Sbjct: 2422 HWQPENVNQAFTRPPPPYPGNIRSPVAPPLGPRYAVFPKDQRGPYPPDV-ASMGMRPHGF 2480

Query: 2216 -LPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQAL---QQRILQQQQMKQQIGSPG 2271
                 G S G M +Q   L    Q   G+  +P +++++     R L   QM   +G P 
Sbjct: 2481 RFGFPGGSHGTMPSQERFL-VPPQQIQGSGVSPQLRRSVSVDMPRPLNNSQMNNPVGLPQ 2539

Query: 2272 QPNPMS--PQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQS-PRPQSQPPHSSPSPR 2328
              +P S   QQH + GQ   +++  +  A     ++   AP  S     S   H +  PR
Sbjct: 2540 HFSPQSLPVQQHNILGQ---AYIELRHRAPDGRQRLPFSAPPGSVVEASSNLRHGNFIPR 2596

Query: 2329 IQPQPSPHHVSPQTGSP---------HPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSR 2379
                P P H  P    P         HP L     S  +QGH  +   S ++  LN P  
Sbjct: 2597 -PDFPGPRHTDPMRRPPQGLPNQLPVHPDLEQVPPSQQEQGHSVH-SSSMVMRTLNHPLG 2654

Query: 2380 SALSS---ELSLVGDTTGDTLE 2398
               S      S+  +TT D L+
Sbjct: 2655 GEFSEAPLSTSVPSETTSDNLQ 2676



 Score = 58.2 bits (139), Expect = 1e-07
 Identities = 89/331 (26%), Positives = 123/331 (37%), Gaps = 50/331 (15%)

Query: 1977 SMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRM-PSVQPPRSISPSALQDLLRT 2035
            SM   Q +Q    Q++    +    I  Q Q A+A P M PSVQP   + P A    +  
Sbjct: 3242 SMVQKQLEQIRKQQKEHAELIEDYRIKQQQQCAMAPPTMMPSVQPQPPLIPGATPPTMSQ 3301

Query: 2036 LKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKY-VANQPGMQPQPGLQSQPGMQPQPG 2094
               P  PQQ Q          Q     I   T+   + + PG QP     S P   P   
Sbjct: 3302 PTFPMVPQQLQH---------QQHTTVISGHTSPVRMPSLPGWQPN----SAPAHLPLNP 3348

Query: 2095 MHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQ-GQALNIMNPGHNPNMASMNPQYR- 2152
               QP +  L  ++   P PG       +   NPQ G    +    +NP   S   + R 
Sbjct: 3349 PRIQPPIAQL-PIKTCTPAPGT------VSNANPQSGPPPRVEFDDNNPFSESFQERERK 3401

Query: 2153 -------EMLRRQLLQQQQQQQQQQQQQQQQQQGSAG--MAGGMAGHGQ----------- 2192
                   E  R QL+Q+  +Q+  QQ+ + +Q G  G  ++       Q           
Sbjct: 3402 ERLREQQERQRIQLMQEVDRQRALQQRMEMEQHGMVGSEISSSRTSVSQIPFYSSDLPCD 3461

Query: 2193 FQQPQGPGGYPPAMQQQ--QRMQQHLPLQG---SSMGQMAAQMGQLGQMGQPGLGADSTP 2247
            F QP GP    P  QQQ  Q +QQ    QG   S   Q   Q  +  Q+G P    DS P
Sbjct: 3462 FMQPLGPLQQSPQHQQQMGQVLQQQNIQQGSINSPSTQTFMQTNERRQVGPPSFVPDS-P 3520

Query: 2248 NIQQALQQRILQQQQMKQQIGSPGQPNPMSP 2278
            +I          +Q      G+  Q +P+ P
Sbjct: 3521 SIPVGSPNFSSVKQGHGNLSGTSFQQSPVRP 3551



 Score = 55.8 bits (133), Expect = 5e-07
 Identities = 94/408 (23%), Positives = 140/408 (34%), Gaps = 87/408 (21%)

Query: 648  PAPGAQPPVIPQAQPVRPP------NGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPM 701
            PAPG      PQ+ P  PP      N P S      +  + +          +QL Q   
Sbjct: 3365 PAPGTVSNANPQSGP--PPRVEFDDNNPFSESFQERERKERLREQQERQ--RIQLMQEVD 3420

Query: 702  GPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQF 761
              RA   +   ++M   G V G  IS SR               ++Q P  S  LP + F
Sbjct: 3421 RQRA---LQQRMEMEQHGMV-GSEISSSR-------------TSVSQIPFYSSDLPCD-F 3462

Query: 762  PSSSGAMSVG------MGQPPAQTGVSQGQVPGAALP-----NPLNMLGPQA--SQLPCP 808
                G +         MGQ   Q  + QG +   +       N    +GP +     P  
Sbjct: 3463 MQPLGPLQQSPQHQQQMGQVLQQQNIQQGSINSPSTQTFMQTNERRQVGPPSFVPDSPSI 3522

Query: 809  PVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS----GQTPTPT 864
            PV               +G    Q    P  TP  PAAP     PV++S    GQ  T T
Sbjct: 3523 PVGSPNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAAP-----PVANSSLPCGQDSTIT 3577

Query: 865  PG-SVPSATQT----------------QSTPTVQAAAQAQVTPQPQTP------------ 895
             G S P +TQ+                + T   +    A+ T  P TP            
Sbjct: 3578 HGHSYPGSTQSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTKAPSTPHSDITAPPTPGI 3637

Query: 896  ---VQPPSVATP-----QSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNS 947
                  P+V+TP     Q+ Q+   PV    P     Q    ++N++P      +     
Sbjct: 3638 SETTSTPAVSTPSELPQQADQESVEPVGPSTPNMAAGQLCTELENKLPNSDFSQATPNQQ 3697

Query: 948  QQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVK 995
                 +V  L M+T  + E+ + +  E++  P  E  + + Q  S+V+
Sbjct: 3698 TYANSEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVE 3745



 Score = 54.7 bits (130), Expect = 1e-06
 Identities = 130/579 (22%), Positives = 208/579 (35%), Gaps = 161/579 (27%)

Query: 1838 NVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVST 1897
            NV Q S   P      +     STP      A  +     + P+G P      PP T+  
Sbjct: 2892 NVIQASTQLPAQDVINSCGITGSTPVLSSLLANEKSDNSDIRPSGSP------PPPTLPA 2945

Query: 1898 GKPTSQVPAPPPPAQPPPAAVEAARQIE-REAQQQQHLYR--VNINNSMPPGRT------ 1948
              P++ V + PP   PP   ++ A         +  H++   V +N  + PG++      
Sbjct: 2946 S-PSNHVSSLPPFIAPPGRVLDNAMNSNVTVVSRVNHVFSQGVQVNPGLIPGQSTVNHSL 3004

Query: 1949 GMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQA 2008
            G G P +Q  P + +    + +SGP          QQ  +PQ        RP++  +   
Sbjct: 3005 GTGKPATQTGPQT-SQSGTSSMSGP----------QQLMIPQTLAQQNRERPLLLEE--- 3050

Query: 2009 AVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTA 2068
                             P  LQDLL         +QQQQ         + M A I+QR+ 
Sbjct: 3051 ----------------QPLLLQDLL----DQERQEQQQQ---------RQMQAMIRQRSE 3081

Query: 2069 KYVAN-QPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQ-------- 2119
             +  N        P ++++  M    G+++  +  NL          G+PP         
Sbjct: 3082 PFFPNIDFDAITDPIMKAK--MVALKGINKVMAQNNL----------GMPPMVMSRFPFM 3129

Query: 2120 -QQAMGGLNPQGQAL---------NIMNPGHNPNMASMNPQY-REMLRRQL---LQQQQQ 2165
             Q   G  N +GQ L         +I +    PN  +  P +  +  R+Q    LQ+ QQ
Sbjct: 3130 GQVVTGTQNSEGQNLGPQAIPQDGSITHQISRPNPPNFGPGFVNDSQRKQYEEWLQETQQ 3189

Query: 2166 QQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQ 2225
              Q QQ+  ++Q G+   +       Q    +    +P   ++     +H+  Q S + +
Sbjct: 3190 LLQMQQKYLEEQIGAHRKSKKALSAKQRTAKKAGREFP---EEDAEQLKHVTEQQSMVQK 3246

Query: 2226 MAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSG 2285
               Q+ +                 QQ     +++  ++KQQ     Q   M+P   M S 
Sbjct: 3247 QLEQIRK-----------------QQKEHAELIEDYRIKQQ-----QQCAMAPPTMMPSV 3284

Query: 2286 QPQASHLPG--------------------QQIATSLSNQVRSPAPVQSPRPQSQPPHSSP 2325
            QPQ   +PG                    QQ  T +S      +PV+ P      P+S+P
Sbjct: 3285 QPQPPLIPGATPPTMSQPTFPMVPQQLQHQQHTTVISGHT---SPVRMPSLPGWQPNSAP 3341

Query: 2326 S------PRIQP----------QPSPHHVS---PQTGSP 2345
            +      PRIQP           P+P  VS   PQ+G P
Sbjct: 3342 AHLPLNPPRIQPPIAQLPIKTCTPAPGTVSNANPQSGPP 3380



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 114/486 (23%), Positives = 166/486 (34%), Gaps = 68/486 (13%)

Query: 460  TQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQQPP----NLISESALPT 515
            TQ   QV  +Q  Q Q  QQ  + + L  +  + P+ GI +   P     N+    +   
Sbjct: 1770 TQKLEQVKNEQ--QQQQQQQFGSQHLLVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHK 1827

Query: 516  SLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIF 575
             L    P     S S +   +   P A PP     R    + ++Q   S           
Sbjct: 1828 ELFTKQPPSTPTSTSSD--DVFVKPQAPPPPPAPSRIPIQDSLSQAQTSQP--------- 1876

Query: 576  PTPD---PAALKDRRMENLVAYAKKVE-------GDMYESANSRDEYYHLLAEKIYKIQK 625
            P+P    P +   R    +  YAK V        G  +   NS     +           
Sbjct: 1877 PSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPL 1936

Query: 626  ELEEKRRSRLHK-QGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMN 684
            ++ E   +R    + +  +      P A+PP  P+  PV     P SL ++R  V     
Sbjct: 1937 QMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPR--PVMTDQFPKSLGLSRSPVVSEQT 1994

Query: 685  SFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNN 744
            +  P++ G       P  PRA         +     +P     P   P P +  G     
Sbjct: 1995 AKGPIAAGTSDHFTKP-SPRA--------DVFQRQRIPDSYARPLLTPAPLDS-GPGPFK 2044

Query: 745  MMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQ 804
               Q P  SQ  P      +S  +SV   + PA T            P P++      S 
Sbjct: 2045 TPMQPPPSSQD-PYGSVSQASRRLSVDPYERPALT------------PRPIDNFSHNQSN 2091

Query: 805  LPCPPVTQSPLHPTPPPASTAAGMPSLQHTTP-----PGMTPPQPAAPTQPSTPVSSSGQ 859
                P +Q PL P P    + A  PS   + P     P    P    P  P   V S  Q
Sbjct: 2092 ---DPYSQPPLTPHPAVNESFAH-PSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQ 2147

Query: 860  TPTPTPGSVPSATQTQSTP---TVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHA 916
            +      +    +Q   TP   TV   +Q   TP+P T  Q     TP ++Q+   P +A
Sbjct: 2148 SSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPST--QTDLFVTPVTNQRHSDP-YA 2204

Query: 917  QPPGTP 922
             PPGTP
Sbjct: 2205 HPPGTP 2210



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 124/611 (20%), Positives = 195/611 (31%), Gaps = 83/611 (13%)

Query: 1818 QHRLQQAQLMRRRMATMNTRNVPQQSLPSP---------------------TSAPPGTPT 1856
            Q + QQ Q   + +   +  + P   + SP                     T  PP TPT
Sbjct: 1780 QQQQQQQQFGSQHLLVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPT 1839

Query: 1857 QQPS-----TPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPA 1911
               S      PQ P PP  P   P+  S     S A+T  P +     P S    PP P 
Sbjct: 1840 STSSDDVFVKPQAPPPPPAPSRIPIQDS----LSQAQTSQPPSPQVFSPGSSNSRPPSPM 1895

Query: 1912 QPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVS 1971
             P    V   R         +      + N  P          S   P+ +N    N+ S
Sbjct: 1896 DPYAKMVGTPRPPPVGHSFSRRNSAAPVENCTP--------LSSVSRPLQMNETTANRPS 1947

Query: 1972 GPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQD 2031
             PV            P  +    P  PRPV++ Q   ++   R P V    +  P A   
Sbjct: 1948 -PVRDLCSSSTTNNDPYAKP---PDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGT 2003

Query: 2032 LLR-TLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQ 2090
                T  SP +   Q+Q +    + P L  A +      +   +  MQP P  Q   G  
Sbjct: 2004 SDHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDSGPGPF---KTPMQPPPSSQDPYGSV 2060

Query: 2091 PQPGM------HQQPSL-----QNLNAMQAGVP--RPGVPPQQQAMGGLNPQGQALNIMN 2137
             Q         +++P+L      N +  Q+  P  +P + P            +A +   
Sbjct: 2061 SQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFS--Q 2118

Query: 2138 PGHNPNMASMNPQYREM-LRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQP 2196
            PG      S +P  +     R ++    Q     +          G           QQP
Sbjct: 2119 PGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQP 2178

Query: 2197 QGPGG------YPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQ 2250
            Q P        +   +  Q+    +    G+    ++    Q     +P +    T   +
Sbjct: 2179 QTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFT---R 2235

Query: 2251 QALQQRILQQQQ----MKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVR 2306
             ++ + +L   Q       Q   P  P P+       S  P+    PG  ++ + S    
Sbjct: 2236 SSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRP---PGPGLSDTFSRV-- 2290

Query: 2307 SPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPE 2366
            SP+  + P  QS     S S       + H V+ Q   P PG   +  +S +       +
Sbjct: 2291 SPSAARDPYDQSPMTPRSQSDSFGTSQTAHDVADQ---PRPGSEGSFCASSNSPMHSQGQ 2347

Query: 2367 QSAMLPQLNTP 2377
            Q + + QL  P
Sbjct: 2348 QFSGVSQLPGP 2358



 Score = 45.1 bits (105), Expect = 9e-04
 Identities = 70/314 (22%), Positives = 110/314 (35%), Gaps = 58/314 (18%)

Query: 812  QSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSA 871
            QSPL P P       G  S   +    +   QP     PSTP S+S       P + P  
Sbjct: 1807 QSPLTPQP-----GNGNMSPAQSFHKELFTKQP-----PSTPTSTSSDDVFVKPQAPPPP 1856

Query: 872  TQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQ-PTPV--HAQPPGTP------ 922
                  P   + +QAQ +  P      P V +P SS  + P+P+  +A+  GTP      
Sbjct: 1857 PAPSRIPIQDSLSQAQTSQPPS-----PQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVG 1911

Query: 923  ----LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGE 978
                   +AA ++N  P  S     + N        PV ++     +  T  DP     +
Sbjct: 1912 HSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDL---CSSSTTNNDPYAKPPD 1968

Query: 979  PRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTS 1038
                +M +    +  +     ++EQ +       K P             + GT+   T 
Sbjct: 1969 TPRPVMTDQFPKSLGLSRSPVVSEQTA-------KGP------------IAAGTSDHFTK 2009

Query: 1039 PSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLS 1098
            PS PR  +F+ + +  +    L      D    PF+ P+ P       Y  +       S
Sbjct: 2010 PS-PRADVFQRQRIPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSV-------S 2061

Query: 1099 TIKRKLDTGQYQEP 1112
               R+L    Y+ P
Sbjct: 2062 QASRRLSVDPYERP 2075



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 121/537 (22%), Positives = 186/537 (34%), Gaps = 75/537 (13%)

Query: 1885 SVARTQPPTTVSTGKPTSQVPAPPPPAQPPPA----AVEAARQIEREAQQQQHLYRVNIN 1940
            S A TQP          + +P PPPP Q  P     A      +        HL     +
Sbjct: 1529 SPANTQP----------TPLPQPPPPTQLLPIHNQDAFSRMPLMNGLIGSSPHLP----H 1574

Query: 1941 NSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQW-QQAPLPQQQ--PMPGL 1997
            NS+PPG +G+GT  S +A  S    R    +   M S P   W   AP  + +   M   
Sbjct: 1575 NSLPPG-SGLGT-FSAIAQSSYPDARDKNSAFNPMASDPNNSWTSSAPTVEGENDTMSNA 1632

Query: 1998 PRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQ 2057
             R  +  + + A+    M +V P           L   +  P+  ++       +K   +
Sbjct: 1633 QRSTLKWEKEEALG--EMATVAPV----------LYTNINFPNLKEEFPDWTTRVKQIAK 1680

Query: 2058 LMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVP 2117
            L      Q  A YV  Q     +  L+          M +Q    +++        P   
Sbjct: 1681 LWRKASSQERAPYV--QKARDNRAALRINKVQMSNDSMKRQQQQDSID--------PSSR 1730

Query: 2118 PQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQ 2177
               +       Q ++ +         M   + Q  ++   Q L+Q + +QQQQQQQQ   
Sbjct: 1731 IDSELFKDPLKQRESEHEQEWKFRQQMRQKSKQQAKIEATQKLEQVKNEQQQQQQQQFGS 1790

Query: 2178 QGSAGMAGGMAGHGQFQQP----QGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQL 2233
            Q     +G        Q P     G G   PA    + +    P   S+    ++    +
Sbjct: 1791 QHLLVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQP--PSTPTSTSSDDVFV 1848

Query: 2234 GQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQ-----PNPMSPQQHMLSGQPQ 2288
                 P   A S   IQ +L Q     Q    Q+ SPG      P+PM P   M+ G P+
Sbjct: 1849 KPQAPPPPPAPSRIPIQDSLSQ-AQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMV-GTPR 1906

Query: 2289 ASHLPGQQIATSLSNQVRSPAPVQSPRP---QSQPPHSSPSPRIQPQPSPHHVSPQTGSP 2345
                    +  S S +  S APV++  P    S+P   + +   +P P     S  T + 
Sbjct: 1907 P-----PPVGHSFSRR-NSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNN 1960

Query: 2346 HPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVE 2402
             P      A   D      P  +   P+    SRS + SE +  G     T + F +
Sbjct: 1961 DP-----YAKPPD---TPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTK 2009



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 101/516 (19%), Positives = 182/516 (35%), Gaps = 58/516 (11%)

Query: 609  RDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPG-AQPPVIPQAQPV--RP 665
            R++      + + ++ ++   ++R  + + G++G++ +      +Q P      P     
Sbjct: 3405 REQQERQRIQLMQEVDRQRALQQRMEMEQHGMVGSEISSSRTSVSQIPFYSSDLPCDFMQ 3464

Query: 666  PNGPLSL-PVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGM 724
            P GPL   P ++ Q+ Q +   N +  G++  P      +     N   Q+     VP  
Sbjct: 3465 PLGPLQQSPQHQQQMGQVLQQQN-IQQGSINSPST----QTFMQTNERRQVGPPSFVPDS 3519

Query: 725  AISPSRMPQPPNMMGAHTN---NMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQT-- 779
               P   P   ++   H N       Q+P +  F P           S+  GQ    T  
Sbjct: 3520 PSIPVGSPNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAAPPVANSSLPCGQDSTITHG 3579

Query: 780  ----GVSQG--QVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQH 833
                G +Q   Q+    +P           +        +    TP    TA   P +  
Sbjct: 3580 HSYPGSTQSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTKAPSTPHSDITAPPTPGISE 3639

Query: 834  TT--PPGMTP---PQPA-----APTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAA 883
            TT  P   TP   PQ A      P  PSTP  ++GQ  T     +P++  +Q+TP  Q  
Sbjct: 3640 TTSTPAVSTPSELPQQADQESVEPVGPSTPNMAAGQLCTELENKLPNSDFSQATPNQQTY 3699

Query: 884  AQAQV------TPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTP 937
            A ++V      TP     ++     T     Q+   +  Q        A A   +   +P
Sbjct: 3700 ANSEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVEGNAVACPVSSAQSP 3759

Query: 938  SSVASAETNSQQPGPDV--PVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVK 995
               A A       G ++   +L+ K  +   + +P+         S   E+D    +++ 
Sbjct: 3760 PHSAGAPAAKGDSGNELLKHLLKNKKSSSLLNQKPE--------GSICSEDDCTKDNKLV 3811

Query: 996  EETDIAE-------QKSEPMEVDEKKPEVK--VEVKEEEESSSNGTASQSTSPSQPRKKI 1046
            E+ + AE       Q         + P+     E K++    +  T  ++   S+ RK  
Sbjct: 3812 EKQNPAEGLQTLGAQMQGGFGCGNQLPKTDGGSETKKQRSKRTQRTGEKAAPRSKKRK-- 3869

Query: 1047 FKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLL 1082
             K EE +QA+  + +       ++     P  P  L
Sbjct: 3870 -KDEEEKQAMYSSTDTFTHLKQQNNLSNPPTPPASL 3904



 Score = 40.0 bits (92), Expect = 0.028
 Identities = 37/129 (28%), Positives = 53/129 (41%), Gaps = 26/129 (20%)

Query: 1808 IKHKLRQQQ-IQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQ 1866
            +KH   QQ  +Q +L+Q +  ++  A +    +    +          PT  PS    PQ
Sbjct: 3234 LKHVTEQQSMVQKQLEQIRKQQKEHAEL----IEDYRIKQQQQCAMAPPTMMPSVQ--PQ 3287

Query: 1867 PPAQPQPSPVSMSPAGFPSVART---QPPTTVSTG-------------KPTS---QVPAP 1907
            PP  P  +P +MS   FP V +    Q  TTV +G             +P S    +P  
Sbjct: 3288 PPLIPGATPPTMSQPTFPMVPQQLQHQQHTTVISGHTSPVRMPSLPGWQPNSAPAHLPLN 3347

Query: 1908 PPPAQPPPA 1916
            PP  QPP A
Sbjct: 3348 PPRIQPPIA 3356



 Score = 38.5 bits (88), Expect = 0.080
 Identities = 92/395 (23%), Positives = 133/395 (33%), Gaps = 54/395 (13%)

Query: 624  QKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLS--LPVNRMQVSQ 681
            Q + E+ R+ +  ++ IL  Q      G Q     Q  P  P  GPL    P N   V+Q
Sbjct: 2375 QADTEKLRQRQKLREIILQQQQQKKIAGRQEKG-SQDSPAVPHPGPLQHWQPEN---VNQ 2430

Query: 682  GMNSFNPMSLGNVQLPQAP-MGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGA 740
                  P   GN++ P AP +GPR A         +  G  P    S    P        
Sbjct: 2431 AFTRPPPPYPGNIRSPVAPPLGPRYAV-----FPKDQRGPYPPDVASMGMRPH--GFRFG 2483

Query: 741  HTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGP 800
                     P+Q +FL   Q    SG        P  +  VS        +P PLN    
Sbjct: 2484 FPGGSHGTMPSQERFLVPPQQIQGSGV------SPQLRRSVS------VDMPRPLNN--- 2528

Query: 801  QASQLPCPPVTQSPLHPTPPPAST----AAGMPSLQHTTPPGMT----PPQPAAPTQPST 852
              SQ+  P        P   P             L+H  P G         P +  + S+
Sbjct: 2529 --SQMNNPVGLPQHFSPQSLPVQQHNILGQAYIELRHRAPDGRQRLPFSAPPGSVVEASS 2586

Query: 853  PVSSSGQTPTPT-PGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQP 911
             +      P P  PG  P  T     P        Q  P  Q PV P     P S Q+Q 
Sbjct: 2587 NLRHGNFIPRPDFPG--PRHTDPMRRPP-------QGLPN-QLPVHPDLEQVPPSQQEQG 2636

Query: 912  TPVHAQP-PGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAED--- 967
              VH+       L+       +  P  +SV S  T+        P   ++ +  ++D   
Sbjct: 2637 HSVHSSSMVMRTLNHPLGGEFSEAPLSTSVPSETTSDNLQITTQPSDGLEEKLDSDDPSV 2696

Query: 968  TEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAE 1002
             E D  + +G    ++ +EDL+  +   E+  + E
Sbjct: 2697 KELDVKDLEGVEVKDLDDEDLENLNLDTEDGKVVE 2731



 Score = 38.1 bits (87), Expect = 0.11
 Identities = 42/188 (22%), Positives = 61/188 (32%), Gaps = 38/188 (20%)

Query: 828  MPSLQHTTP--PGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQ 885
            MPS+Q   P  PG TPP  + PT P  P     Q  T       S  +  S P  Q  + 
Sbjct: 3281 MPSVQPQPPLIPGATPPTMSQPTFPMVPQQLQHQQHTTVISGHTSPVRMPSLPGWQPNSA 3340

Query: 886  AQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAET 945
                P     +QPP    P                         I    P P +V++A  
Sbjct: 3341 PAHLPLNPPRIQPPIAQLP-------------------------IKTCTPAPGTVSNANP 3375

Query: 946  NSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGAS-QVKEETDIAEQK 1004
             S  P             + +D  P     +   R E + E  +    Q+ +E D     
Sbjct: 3376 QSGPP----------PRVEFDDNNPFSESFQERERKERLREQQERQRIQLMQEVDRQRAL 3425

Query: 1005 SEPMEVDE 1012
             + ME+++
Sbjct: 3426 QQRMEMEQ 3433



 Score = 35.0 bits (79), Expect = 0.89
 Identities = 71/317 (22%), Positives = 110/317 (34%), Gaps = 78/317 (24%)

Query: 644  QPALPAPGAQPPVI-----------PQAQPVRPPNGPLSLPVN------RMQVSQGMNSF 686
            QP  P P  Q  +            P A P   P   +S+P +      R ++S+G   F
Sbjct: 2177 QPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEG---F 2233

Query: 687  NPMSLGN-VQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISP----SRMPQPPNMMGAH 741
               S+   V +P      +AA         N   ++PG  + P    S+ P+PP    + 
Sbjct: 2234 TRSSMTRPVLMPNQDPFLQAAQ--------NRGPALPGPLVRPPDTCSQTPRPPGPGLSD 2285

Query: 742  TNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPG------AALPNPL 795
            T + ++ + A+    P +Q P +  + S   G       V+    PG      A+  +P+
Sbjct: 2286 TFSRVSPSAARD---PYDQSPMTPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSNSPM 2342

Query: 796  NMLGPQ---ASQLPCPPVTQSPLHPTPPPASTA--------------------------A 826
            +  G Q    SQLP  PV  S +  T    + A                          A
Sbjct: 2343 HSQGQQFSGVSQLP-GPVPTSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKKIA 2401

Query: 827  GMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQA 886
            G         P +  P P    QP     +  + P P PG++ S       P      + 
Sbjct: 2402 GRQEKGSQDSPAVPHPGPLQHWQPENVNQAFTRPPPPYPGNIRSPVAPPLGP------RY 2455

Query: 887  QVTPQPQTPVQPPSVAT 903
             V P+ Q    PP VA+
Sbjct: 2456 AVFPKDQRGPYPPDVAS 2472



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 45/188 (23%), Positives = 67/188 (35%), Gaps = 32/188 (17%)

Query: 801  QASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQT 860
            Q + L  PP   + L PTPPP +              G    +  A            +T
Sbjct: 3890 QQNNLSNPPTPPASLPPTPPPMAC--------QKMANGFATTEELAGKAGVLVSHEVTKT 3941

Query: 861  PTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQ---------- 910
              P P  +P   Q      + A A AQ    P+T   P S+ TP  + Q+          
Sbjct: 3942 LGPKPFQLPFRPQDD----LLARALAQ---GPKTVDVPASLPTPPHNNQEELRIQDHCGD 3994

Query: 911  -PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLE----MKTETQA 965
              TP    P  +P S     + +R P   S+   E     P P +P+L       +E++ 
Sbjct: 3995 RDTPDSFVPSSSPESVVGVEV-SRYP-DLSLVKEEPPEPVPSPIIPILPSTAGKSSESRR 4052

Query: 966  EDTEPDPG 973
             D + +PG
Sbjct: 4053 NDIKTEPG 4060



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 51/210 (24%), Positives = 76/210 (36%), Gaps = 28/210 (13%)

Query: 802  ASQLPCPPVTQSP--LHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQ 859
            ++QLP   V  S      TP  +S  A   S      P  +PP P  P  PS  VSS   
Sbjct: 2897 STQLPAQDVINSCGITGSTPVLSSLLANEKSDNSDIRPSGSPPPPTLPASPSNHVSSLPP 2956

Query: 860  TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPP 919
               P PG V       +   V     ++V       VQ      P     Q T  H+   
Sbjct: 2957 FIAP-PGRVLDNAMNSNVTVV-----SRVNHVFSQGVQ----VNPGLIPGQSTVNHSLGT 3006

Query: 920  GTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEP 979
            G P +Q          T  S  S+ +  QQ         M  +T A+     P   + +P
Sbjct: 3007 GKPATQTGPQ------TSQSGTSSMSGPQQ--------LMIPQTLAQQNRERPLLLEEQP 3052

Query: 980  --RSEMMEEDLQGASQVKEETDIAEQKSEP 1007
                ++++++ Q   Q ++   +  Q+SEP
Sbjct: 3053 LLLQDLLDQERQEQQQQRQMQAMIRQRSEP 3082



 Score = 32.0 bits (71), Expect = 7.5
 Identities = 50/232 (21%), Positives = 87/232 (37%), Gaps = 35/232 (15%)

Query: 891  QPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASID--NRVPTPSSVASAETNSQ 948
            QPQ P  PP    P +    P     +P G P    A+      + P      + E    
Sbjct: 11   QPQPPPPPPE--EPGAPAPSPAAADKRPRGRPRKDGASPFQRARKKPRSRGKTAVEDEDS 68

Query: 949  QPGPD------VPVLEMKTETQAEDTEPDPGESK---GEPRSEMMEEDLQGASQVKEETD 999
              G +      +   E+K ++  ED E +   SK      +  + EE       V  E  
Sbjct: 69   MDGLETTETETIVETEIKEQSAEEDAEAEVDNSKQLIPTLQRSVSEESANSLVSVGVEAK 128

Query: 1000 IAEQ---------KSEPMEVDEKKPEV----------KVEVKEEEESSSNGTASQSTSPS 1040
            I+EQ         KS   + D K+  +          +   K++ + +SNGT  +  + S
Sbjct: 129  ISEQLCAFCYCGEKSSLGQGDLKQFRITPGFILPWRNQPSNKKDIDDNSNGTYEKMQN-S 187

Query: 1041 QPRKKIFKPEEL--RQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDI 1090
             PRK+  + +E   +Q ++  +    +   +    +   +  L+G+PD  DI
Sbjct: 188  APRKQRGQRKERSPQQNIVSCVSVSTQTASDDQAGKLWDELSLVGLPDAIDI 239


>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
          Length = 2063

 Score = 82.4 bits (202), Expect = 5e-15
 Identities = 155/575 (26%), Positives = 213/575 (37%), Gaps = 82/575 (14%)

Query: 1813 RQQQIQ--HRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTP---QTPQP 1867
            +QQQ Q   + QQ Q ++ R    + +  PQ   P  T+     PTQ P  P   Q P  
Sbjct: 270  QQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTA-----PTQVPVPPGWNQLPSG 324

Query: 1868 PAQPQPSPVSM----SPAGFPSVARTQPPTTVSTGKP---TSQVPAPPPPAQPPPAAVEA 1920
              QP P+  S+    +  G+       P       +P   T Q P+ PPP  P P   + 
Sbjct: 325  ALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPP--PYPFGSQQ 382

Query: 1921 ARQIEREAQQQQH--LYRVNINNSMPPGRTGMGTPGSQ-----MAPVSLNVPRPNQVSGP 1973
            A Q      Q  +   +      S+  G + + TP  Q      +P S   P   Q   P
Sbjct: 383  ASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPAS--SPSSFQQGSP 440

Query: 1974 V-MPSMPPGQWQQAPL-PQQQPMP-GLPRPVIS-----MQAQAAVAGPRMPSVQPPRSIS 2025
               P++   Q Q  P  PQ  P+P G  +PV S     M  Q  V    M   Q P +  
Sbjct: 441  ASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQG 500

Query: 2026 PSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQS 2085
            P +L   L  +     P++     +  ++NP  M   +   T    A  PG    P LQ+
Sbjct: 501  PQSLHPGLGGM-----PKRLPPGFSAGQANPNFMQGQVPSTT----ATTPGNSGAPQLQA 551

Query: 2086 QPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMA 2145
               +Q   G    P  QN   +  G P    P      G +N Q QA     P    N++
Sbjct: 552  NQNVQHAGGQGAGPP-QNQMQVSHGPPNMMQPSLMGIHGNMNNQ-QAGTSGVP--QVNLS 607

Query: 2146 SMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPA 2205
            +M  Q ++    QL+    QQ    Q Q  QQQG+      M        PQG     P 
Sbjct: 608  NMQGQPQQGPPSQLM-GMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPP 666

Query: 2206 MQ----QQQRM---QQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRIL 2258
             Q      QRM   +Q L  QG  M  MA     +G  GQ  L     P I+Q +     
Sbjct: 667  SQNLGPSPQRMTPPKQMLSQQGPQM--MAPHNQMMGPQGQVLL--QQNPMIEQIMTN--- 719

Query: 2259 QQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQS 2318
            Q Q  KQQ  +  Q N M     ++ G          Q    +S Q+          PQ 
Sbjct: 720  QMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQFTGQMSGQM---------LPQQ 770

Query: 2319 QPPHSSPSPRI--------QPQPSPHHVSPQTGSP 2345
             P ++SPS  +         P PSP H++ Q G P
Sbjct: 771  GPVNNSPSQVMGIQGQVLRPPGPSP-HMAQQHGDP 804



 Score = 79.3 bits (194), Expect = 4e-14
 Identities = 99/345 (28%), Positives = 130/345 (37%), Gaps = 48/345 (13%)

Query: 2077 MQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRP---GVPPQQQAMGGLNPQGQAL 2133
            M P  G  S   M P P    QP      A Q+    P   G+  QQQ+    +P G   
Sbjct: 183  MIPPGGNVSSSMMAPGPNPELQPRTPR-PASQSDAMDPLLSGLHIQQQS----HPSGS-- 235

Query: 2134 NIMNPGHNPNMA-----SMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMA 2188
              + P H+P         MNP     L++Q  QQQQQQQQQQQQQQQQQQ    +     
Sbjct: 236  --LAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQ--LQARPP 291

Query: 2189 GHGQFQQPQG---------PGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMG-------- 2231
               Q QQPQG             PP   Q        P    S+G M A  G        
Sbjct: 292  QQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPG 351

Query: 2232 --QLGQMGQPGLGADSTPNIQQAL----QQRILQQQQMKQQIGSPGQPNPMSPQQHMLSG 2285
              Q     +P L    TP+          Q+  Q      Q+ +PGQ    +PQ   L G
Sbjct: 352  PMQQQLQARPSLATVQTPSHPPPPYPFGSQQASQAHTNFPQMSNPGQFT--APQMKSLQG 409

Query: 2286 QPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSP 2345
             P     P QQ   +  +   SP+  Q   P S P  +    ++ P+P  ++  PQ G  
Sbjct: 410  GPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQ-GFQ 468

Query: 2346 HPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSALSSELSLVG 2390
             P  +      + Q   GN   + M+ Q   P++   S    L G
Sbjct: 469  QPVSSPGRNPMVQQ---GNVPPNFMVMQQQPPNQGPQSLHPGLGG 510



 Score = 78.6 bits (192), Expect = 7e-14
 Identities = 217/952 (22%), Positives = 332/952 (34%), Gaps = 185/952 (19%)

Query: 91   ASSPVQQGLGGQAQGQPNSAN------MASLSAMGKSPLSQGDSSAPS--LPKQAASTSG 142
            ASSP       Q   +P   N         +S+ G++P+ Q  +  P+  + +Q     G
Sbjct: 441  ASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQG 500

Query: 143  PTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNANFNQTH-PGLLNSNSGHSLINQA 201
            P     Q+L+P      G+    P     G     N NF Q   P    +  G+S    A
Sbjct: 501  P-----QSLHPGLG---GMPKRLPPGFSAGQA---NPNFMQGQVPSTTATTPGNS---GA 546

Query: 202  SQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLAETLTQVSPQMTGHAGLNTAQA 261
             Q QA   N ++  AG G+GAG P     +     +++  +L  +      H  +N  QA
Sbjct: 547  PQLQA---NQNVQHAG-GQGAGPPQNQMQVSHGPPNMMQPSLMGI------HGNMNNQQA 596

Query: 262  G--GMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASKQS-MVNSLPTF-PTDIKNT 317
            G  G+ ++ ++      GQP     G P    G++ Q+   Q  MV    T  P +    
Sbjct: 597  GTSGVPQVNLSNMQ---GQPQQ---GPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMIL 650

Query: 318  SVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVLLLHAH------KCQRRE 371
            S   +    QM  +    P+Q +   P      ++++ QQ   ++  H      + Q   
Sbjct: 651  SRAQLMPQGQMMVNP---PSQNLGPSPQRMTPPKQMLSQQGPQMMAPHNQMMGPQGQVLL 707

Query: 372  QANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQAILGSPASGIQNTIGSVGTGQQNATS 431
            Q N  +        +  K   N             I+  P   +Q  +    TGQ +   
Sbjct: 708  QQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPGPAQIMRGPTPNMQGNMVQF-TGQMSGQM 766

Query: 432  LSNPNPIDPSSMQRAYAALGL-----------PYMNQPQ-------------TQLQPQVP 467
            L    P++ S  Q     +G+           P+M Q               +Q+ P V 
Sbjct: 767  LPQQGPVNNSPSQ----VMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVS 822

Query: 468  GQQPAQPQTHQQMRTLNPLGNN-------PMNIPAGG------ITTDQQPPNLISESALP 514
             QQ      H Q    N    N         N P  G      ++  Q P   +++    
Sbjct: 823  IQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTL 882

Query: 515  TSLGATNPLMND------GSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVH 568
            TS    N L +D      G N+    T +  P    P     +    +  T D R   + 
Sbjct: 883  TSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKK-KNSQQDLNTPDTRPAGLE 941

Query: 569  KLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELE 628
            +  Q   P      L D     L  ++ +  G  Y S                   + +E
Sbjct: 942  EADQPPLPGEQGINL-DNSGPKLPEFSNRPPG--YPS-------------------QPVE 979

Query: 629  EKRRSRLHKQGILGNQPALPAPGAQP-PVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFN 687
            ++   ++  Q +    P    P  QP P +PQ Q   PP+ P S    + Q    M    
Sbjct: 980  QRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMM 1039

Query: 688  PMSLGNVQLP-----QAPMGPRAASPMNHSVQMNSMGSVPGM-------AISPS----RM 731
                 +V+LP       P GP   +P +  + M   GSVP M       ++ PS    RM
Sbjct: 1040 QQDPKSVRLPVSQNVHPPRGP--LNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRM 1097

Query: 732  PQPPNM-MGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAA 790
            P P N  +G+++  M+ Q        PQN  PSSS      M   P  +G     VPG  
Sbjct: 1098 PMPVNTPLGSNSRKMVYQES------PQN--PSSSPLAE--MASLPEASGSEAPSVPGGP 1147

Query: 791  LPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPP--------GMTPP 842
               P +++ PQ   +   P       P P P S   G    Q   PP        G   P
Sbjct: 1148 NNMPSHVVLPQNQLMMTGP------KPGPSPLSATQGATPQQ---PPVNSLPSSHGHHFP 1198

Query: 843  QPAAPTQPSTPVSSSGQTPTP----TPGSVPSATQ----TQSTPTVQAAAQAQVTPQPQT 894
              AAPTQ S P + +  +P P    TP + P +T+    + S   + A+      PQ   
Sbjct: 1199 NVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINI 1258

Query: 895  PVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETN 946
            P+ P         QQ   P       T L     +  N    PS+ A+ +T+
Sbjct: 1259 PLPPRPNLNRGFDQQGLNP-------TTLKAIGQAPSNLTMNPSNFATPQTH 1303



 Score = 72.8 bits (177), Expect = 4e-12
 Identities = 154/601 (25%), Positives = 212/601 (35%), Gaps = 93/601 (15%)

Query: 1830 RMATMNTRNVPQQSLPSPTSAPPGTPTQQ-PSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            + A+    N PQ S P   +AP     Q  PS   TP      QP   + SPA  PS  +
Sbjct: 381  QQASQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQ----QPHLTNKSPASSPSSFQ 436

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPG-R 1947
               P +  T   T Q   P PP                             NN +P G +
Sbjct: 437  QGSPASSPTVNQTQQQMGPRPPQ----------------------------NNPLPQGFQ 468

Query: 1948 TGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMP-GLPRPVISMQA 2006
              + +PG        NVP PN +   VM   PP Q  Q+  P    MP  LP    + QA
Sbjct: 469  QPVSSPGRNPMVQQGNVP-PNFM---VMQQQPPNQGPQSLHPGLGGMPKRLPPGFSAGQA 524

Query: 2007 QAAVAGPRMPS---VQPPRSISP--SALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAA 2061
                   ++PS     P  S +P   A Q++       + P Q Q  + +    P +M  
Sbjct: 525  NPNFMQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQ--MQVSHGPPNMMQP 582

Query: 2062 FIKQRTAKYVANQPGMQ--PQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQ 2119
             +          Q G    PQ  L +  G QPQ G    P  Q +   Q  VP  G   Q
Sbjct: 583  SLMGIHGNMNNQQAGTSGVPQVNLSNMQG-QPQQG----PPSQLMGMHQQIVPSQGQMVQ 637

Query: 2120 QQAMGGLNPQGQAL----NIMNPGH---NPNMASMNPQYREML-RRQLLQQQQQQQQQQQ 2171
            QQ  G LNPQ   +     +M  G    NP   ++ P  + M   +Q+L QQ  Q     
Sbjct: 638  QQ--GTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQMLSQQGPQMMAPH 695

Query: 2172 QQQQQQQGSA----------GMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGS 2221
             Q    QG             M   M G+ Q    Q      P     Q M+   P    
Sbjct: 696  NQMMGPQGQVLLQQNPMIEQIMTNQMQGNKQQFNTQNQSNVMPG--PAQIMRGPTPNMQG 753

Query: 2222 SMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQ----QQQMKQQIGSPGQP--NP 2275
            +M Q   QM   GQM       +++P+    +Q ++L+       M QQ G P     N 
Sbjct: 754  NMVQFTGQMS--GQMLPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANND 811

Query: 2276 MSPQQHMLSGQPQASHLPGQQI----ATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQP 2331
            +S  Q M     Q +++    +      S S    S   +    P S  P+ +     Q 
Sbjct: 812  VSLSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQN 871

Query: 2332 QPSPHHVSPQTGSPHPGLAVTMASSIDQGHLG-NPEQ---SAMLPQLNTPSRSALSSELS 2387
               P  V+       P L   + S I  GH G N +Q   +A  P+   P R   +S+  
Sbjct: 872  PGFP--VNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQD 929

Query: 2388 L 2388
            L
Sbjct: 930  L 930



 Score = 65.9 bits (159), Expect = 5e-10
 Identities = 116/530 (21%), Positives = 168/530 (31%), Gaps = 113/530 (21%)

Query: 431 SLSNPN-PIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNN 489
           SL+ P+ P+ P S+ R       P + Q Q Q Q Q   QQ  Q Q  QQ     P   +
Sbjct: 235 SLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQH 294

Query: 490 PMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTG 549
                       QQP  +  +   PT +         G N    G L   P      +  
Sbjct: 295 QQ----------QQPQGIRPQFTAPTQVPVP-----PGWNQLPSGALQPPPAQGSLGTMT 339

Query: 550 VRKGWHEH-----VTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYE 604
             +GW +      + Q L++      VQ     P P     ++       A +   +  +
Sbjct: 340 ANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQ-------ASQAHTNFPQ 392

Query: 605 SANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVR 664
            +N         A ++  +Q                 G    +P P  QP +  ++    
Sbjct: 393 MSNPGQ----FTAPQMKSLQ-----------------GGPSRVPTPLQQPHLTNKSPASS 431

Query: 665 PPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGM 724
           P +     P +   V+Q      P    N  LPQ    P ++   N  VQ  ++      
Sbjct: 432 PSSFQQGSPASSPTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNV------ 485

Query: 725 AISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGA---MSVGMGQPPAQTGV 781
                    PPN M      M  Q P Q    PQ+  P   G    +  G     A    
Sbjct: 486 ---------PPNFMV-----MQQQPPNQG---PQSLHPGLGGMPKRLPPGFSAGQANPNF 528

Query: 782 SQGQVPGAALPNPLNMLGPQ----------ASQLPCPPVTQSPLHPTPP----------- 820
            QGQVP      P N   PQ            Q   PP  Q  +   PP           
Sbjct: 529 MQGQVPSTTATTPGNSGAPQLQANQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIH 588

Query: 821 -----PASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQ 875
                  +  +G+P +  +   G   PQ   P+Q    +    Q   P+ G +     T 
Sbjct: 589 GNMNNQQAGTSGVPQVNLSNMQGQ--PQQGPPSQ----LMGMHQQIVPSQGQMVQQQGTL 642

Query: 876 STPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQ 925
           +       ++AQ+ PQ Q  V PP      S    P+P    PP   LSQ
Sbjct: 643 NPQNPMILSRAQLMPQGQMMVNPP------SQNLGPSPQRMTPPKQMLSQ 686



 Score = 62.8 bits (151), Expect = 4e-09
 Identities = 126/475 (26%), Positives = 165/475 (34%), Gaps = 79/475 (16%)

Query: 1923 QIERE-----AQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPS 1977
            QIE E     A  Q     V +N  M  G +     G  MA    + P   +++ P    
Sbjct: 128  QIEGEGAINLALAQNRSQDVRMNGPMGAGNSVRMEAGFPMA----SGPGIIRMNNPATVM 183

Query: 1978 MPPG----QWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLL 2033
            +PPG        AP P  +  P  PRP     +Q+    P +  +   +   PS      
Sbjct: 184  IPPGGNVSSSMMAPGPNPELQPRTPRPA----SQSDAMDPLLSGLHIQQQSHPSG----- 234

Query: 2034 RTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQP 2093
             +L  P  P Q   V    + NP               AN P +Q Q   Q Q   Q Q 
Sbjct: 235  -SLAPPHHPMQPVSVNR--QMNP---------------ANFPQLQQQQQQQQQQQQQQQ- 275

Query: 2094 GMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALN--IMNPGHN--PNMASMNP 2149
               QQ   Q    +QA   RP    QQQ   G+ PQ  A     + PG N  P+ A   P
Sbjct: 276  ---QQQQQQQQQQLQA---RPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPP 329

Query: 2150 QYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQP-QGPGGYPPAMQQ 2208
              +  L      Q  ++       QQQ Q    +A         Q P   P  YP   QQ
Sbjct: 330  PAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLA-------TVQTPSHPPPPYPFGSQQ 382

Query: 2209 QQRMQQHLPLQGSSMGQMAA-QMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQI 2267
              +   + P Q S+ GQ  A QM  L    Q G     TP  Q  L  +         Q 
Sbjct: 383  ASQAHTNFP-QMSNPGQFTAPQMKSL----QGGPSRVPTPLQQPHLTNKSPASSPSSFQQ 437

Query: 2268 GSP-GQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRP------QSQP 2320
            GSP   P     QQ M    PQ + LP Q     +S+  R+P   Q   P      Q QP
Sbjct: 438  GSPASSPTVNQTQQQMGPRPPQNNPLP-QGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQP 496

Query: 2321 PHSSPS---PRIQPQPSPHHVSPQTGSPHPGL---AVTMASSIDQGHLGNPEQSA 2369
            P+  P    P +   P         G  +P      V   ++   G+ G P+  A
Sbjct: 497  PNQGPQSLHPGLGGMPKRLPPGFSAGQANPNFMQGQVPSTTATTPGNSGAPQLQA 551



 Score = 60.8 bits (146), Expect = 2e-08
 Identities = 141/596 (23%), Positives = 203/596 (34%), Gaps = 97/596 (16%)

Query: 1823 QAQLMRRRMATMNTRNVPQQSLPSPTSAPPG-TPTQQPSTPQ-TPQPPAQ--PQPSPVSM 1878
            Q Q  +++  T N  NV    +P P     G TP  Q +  Q T Q   Q  PQ  PV+ 
Sbjct: 720  QMQGNKQQFNTQNQSNV----MPGPAQIMRGPTPNMQGNMVQFTGQMSGQMLPQQGPVNN 775

Query: 1879 SPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVN 1938
            SP+    V   Q       G           PA      V  ++ +   + QQ ++   +
Sbjct: 776  SPS---QVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVSLSQMMPDVSIQQTNMVPPH 832

Query: 1939 INNSMPPGRTGMGTPGSQM---APVSLNVPRPNQVSGPVMPSMPPGQ--WQQAPLPQQQP 1993
            +        +G    G  M   AP S   P  NQ+S    P  P  +     +PL     
Sbjct: 833  VQAMQGNSASGNHFSGHGMSFNAPFS-GAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLL 891

Query: 1994 MPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSS-------PQQQQ 2046
               +      +  +        P  + P     ++ QDL      P+        P   +
Sbjct: 892  QSDISAGHFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAGLEEADQPPLPGE 951

Query: 2047 QVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNA 2106
            Q +N+  S P+L             +N+P     PG  SQP       + Q+P  Q    
Sbjct: 952  QGINLDNSGPKLPE----------FSNRP-----PGYPSQP-------VEQRPLQQMPPQ 989

Query: 2107 MQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQ 2166
            +   V  P  PPQQQ      PQ                   PQ  +  +     Q Q Q
Sbjct: 990  LMQHVAPPPQPPQQQ------PQ-------------------PQLPQQQQPPPPSQPQSQ 1024

Query: 2167 QQQQQQQQ-------QQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQ 2219
            QQQQQQQQ       QQ   S  +      H   + P  P      MQQ   +   + LQ
Sbjct: 1025 QQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPP-RGPLNPDSQRMPMQQSGSVPVMVSLQ 1083

Query: 2220 GSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQR-----ILQQQQMKQQIGS----- 2269
            G +    +    ++       LG++S   + Q   Q      + +   + +  GS     
Sbjct: 1084 GPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSV 1143

Query: 2270 PGQPNPMS-----PQ-QHMLSG-QPQASHLPGQQIATSLSNQVRS-PAPVQSPRPQSQPP 2321
            PG PN M      PQ Q M++G +P  S L   Q AT     V S P+      P    P
Sbjct: 1144 PGGPNNMPSHVVLPQNQLMMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAP 1203

Query: 2322 HSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLNTP 2377
              +  P+   + SP    PQT +  P        S+    L         PQ+N P
Sbjct: 1204 TQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIP 1259



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 88/373 (23%), Positives = 132/373 (35%), Gaps = 69/373 (18%)

Query: 1841 QQSLPSPTSAPPGTPTQQPSTPQTPQPPAQ--------PQPSPVSMSPAGFPSVARTQPP 1892
            QQ L +P + P G         Q P P  Q        P+    S  P G+PS    Q P
Sbjct: 927  QQDLNTPDTRPAGLE----EADQPPLPGEQGINLDNSGPKLPEFSNRPPGYPSQPVEQRP 982

Query: 1893 TTVSTGKPTSQVPAPPPP------------AQPPPAAVEAARQIEREAQQQQHL------ 1934
                  +    V  PP P             QPPP +   ++Q +++ QQ   +      
Sbjct: 983  LQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQD 1042

Query: 1935 ---YRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPG-QWQQAPLP- 1989
                R+ ++ ++ P R G   P SQ  P+  +   P  VS     S+PP    Q+ P+P 
Sbjct: 1043 PKSVRLPVSQNVHPPR-GPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPV 1101

Query: 1990 -------------QQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSAL----QDL 2032
                         Q+ P      P+  M +    +G   PSV    +  PS +      L
Sbjct: 1102 NTPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQNQL 1161

Query: 2033 LRT--------LKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPG-MQPQPGL 2083
            + T        L +      QQ  +N L S+       +   T       P    P+P  
Sbjct: 1162 MMTGPKPGPSPLSATQGATPQQPPVNSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYY 1221

Query: 2084 QSQPGMQPQPGMHQQPSL--QNLNAMQAGVPRPGV----PPQQQAMGGLNPQG-QALNIM 2136
               P  +P      + SL  + LNA  AG+  P +    PP+     G + QG     + 
Sbjct: 1222 PQTPNNRPPSTEPSEISLSPERLNASIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLK 1281

Query: 2137 NPGHNPNMASMNP 2149
              G  P+  +MNP
Sbjct: 1282 AIGQAPSNLTMNP 1294



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 144/657 (21%), Positives = 210/657 (31%), Gaps = 145/657 (22%)

Query: 420  GSVGTGQ-QNATSLSN--PNPIDPSSM-------QRAYAALGLPYMNQPQTQLQPQV--P 467
            G  G G  QN   +S+  PN + PS M        +     G+P +N    Q QPQ   P
Sbjct: 559  GGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPP 618

Query: 468  GQQ--------PAQPQTHQQMRTLNPLGNNPM---------------NIPAGGITTDQQ- 503
             Q         P+Q Q  QQ  TLNP   NPM               N P+  +    Q 
Sbjct: 619  SQLMGMHQQIVPSQGQMVQQQGTLNP--QNPMILSRAQLMPQGQMMVNPPSQNLGPSPQR 676

Query: 504  --PPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQD 561
              PP  +     P  +   N +M      G +  L   P      +  ++    +  TQ+
Sbjct: 677  MTPPKQMLSQQGPQMMAPHNQMMGP---QGQV-LLQQNPMIEQIMTNQMQGNKQQFNTQN 732

Query: 562  LRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIY 621
              + +         PTP+          N+V +  ++ G M                   
Sbjct: 733  QSNVMPGPAQIMRGPTPNMQG-------NMVQFTGQMSGQM------------------- 766

Query: 622  KIQKELEEKRRSRLHKQGILGNQPA---------LPAPGAQPPVIPQ-AQPVRPPNGPLS 671
                         L +QG + N P+         L  PG  P +  Q   P    N  +S
Sbjct: 767  -------------LPQQGPVNNSPSQVMGIQGQVLRPPGPSPHMAQQHGDPATTANNDVS 813

Query: 672  LPVNRMQVSQGMNSFNPMSLGNVQLPQAP------MGPRAASPMNHSVQMNSM--GSVPG 723
            L      VS    +  P  +  +Q   A        G    +P + +   N M  G  PG
Sbjct: 814  LSQMMPDVSIQQTNMVPPHVQAMQGNSASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPG 873

Query: 724  MAISPSRMPQPPNMMGA--------------HTNNMMAQAPAQSQFLPQNQFPSSSGAMS 769
              ++       P ++                  NN  A  P + +  P  +  +S   ++
Sbjct: 874  FPVNKDVTLTSPLLVNLLQSDISAGHFGVNNKQNNTNANKPKKKK--PPRKKKNSQQDLN 931

Query: 770  VGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQL-------PCPPVTQSPLHPTPPPA 822
                +P       Q  +PG    N L+  GP+  +        P  PV Q PL   PP  
Sbjct: 932  TPDTRPAGLEEADQPPLPGEQGIN-LDNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQL 990

Query: 823  STAAGMPSLQHTTPPGMTP---PQPAAP--TQPSTPVSSSGQTPTPTPGSVPSATQTQST 877
                    +QH  PP   P   PQP  P   QP  P     Q        +      Q  
Sbjct: 991  --------MQHVAPPPQPPQQQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQD 1042

Query: 878  PTVQAAAQAQVTPQPQTPVQPPSVATP-QSSQQQPTPVHAQ-PPGTPLSQAAASIDNRVP 935
            P       +Q    P+ P+ P S   P Q S   P  V  Q P   P S     +   V 
Sbjct: 1043 PKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVN 1102

Query: 936  TP---SSVASAETNSQQPGPDVPVLEMKTETQAEDTEPD--PGESKGEPRSEMMEED 987
            TP   +S       S Q     P+ EM +  +A  +E    PG     P   ++ ++
Sbjct: 1103 TPLGSNSRKMVYQESPQNPSSSPLAEMASLPEASGSEAPSVPGGPNNMPSHVVLPQN 1159



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 84/390 (21%), Positives = 120/390 (30%), Gaps = 73/390 (18%)

Query: 644 QPALPAPGAQPPVIP------QAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLP 697
           QP  P P +Q   +         Q    P+G L+ P + MQ        NP +   +Q  
Sbjct: 204 QPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQ 263

Query: 698 QAPMGPR-----------------AASPMNHSVQM-----------NSMGSVPGMAISPS 729
           Q     +                 A  P  H  Q              +   PG    PS
Sbjct: 264 QQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPS 323

Query: 730 RMPQPPNMMGA----HTNNMMAQAPAQSQFLPQNQF-PSSSGAMSVGMGQPPAQTGVSQG 784
              QPP   G+      N    +AP       Q Q  PS +   +     PP   G  Q 
Sbjct: 324 GALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQLQARPSLATVQTPSHPPPPYPFGSQQA 383

Query: 785 QVPGAALP---NPLNMLGPQASQLP-----CPPVTQSPLHPTPPPASTAAGMPSLQHTTP 836
                  P   NP     PQ   L       P   Q P      PAS+ +        + 
Sbjct: 384 SQAHTNFPQMSNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSSFQQGSPASS 443

Query: 837 PGMTPPQPAAPTQP--STPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQT 894
           P +   Q     +P  + P+    Q P  +PG  P   Q    P      Q      PQ+
Sbjct: 444 PTVNQTQQQMGPRPPQNNPLPQGFQQPVSSPGRNPMVQQGNVPPNFMVMQQQPPNQGPQS 503

Query: 895 PVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDV 954
            + P     P+            PPG    QA  +   +   PS+ A+   NS  P    
Sbjct: 504 -LHPGLGGMPK----------RLPPGFSAGQANPNF-MQGQVPSTTATTPGNSGAP---- 547

Query: 955 PVLEMKTETQA-EDTEPDPGESKGEPRSEM 983
                  + QA ++ +   G+  G P+++M
Sbjct: 548 -------QLQANQNVQHAGGQGAGPPQNQM 570



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 74/332 (22%), Positives = 123/332 (37%), Gaps = 44/332 (13%)

Query: 654  PPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLP----QAPMGPRAASPM 709
            PPV+  ++PV   +    LP N++ V    N     +  +  LP     A M      P 
Sbjct: 1576 PPVM--SRPVSSSSISTPLPPNQITVFVTSNPITTSANTSAALPTHLQSALMSTVVTMPN 1633

Query: 710  NHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMS 769
              S  M S G     + +  +   P  +  +    +M  +  Q   +P     ++SG M 
Sbjct: 1634 AGSKVMVSEGQSAAQSNARPQFITPVFINSSSIIQVMKGS--QPSTIPAAPLTTNSGLMP 1691

Query: 770  -----VGMGQPPAQTGVSQGQVPGAAL-----PN-----PLNMLGPQAS--QLPCPPVTQ 812
                 VG    P     S   VP  AL     PN     PL +L  +A+  QLP PP T 
Sbjct: 1692 PSVAVVGPLHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPL-VLSSRATPVQLPSPPCTS 1750

Query: 813  SPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSAT 872
            SP+ P+ PP      +  ++   P   +P    +  Q + P S S    +P   + P ++
Sbjct: 1751 SPVVPSHPP------VQQVKELNPDEASPQVNTSADQNTLPSSQSTTMVSPLLTNSPGSS 1804

Query: 873  QTQSTPTVQAAAQAQVTPQPQ---TPVQPPSVATPQSSQQQ--------PTPVHAQPPG- 920
              + +P   +  + +V    Q   T        + +  ++Q           +    PG 
Sbjct: 1805 GNRRSPVSSSKGKGKVDKIGQILLTKACKKVTGSLEKGEEQYGADGETEGQGLDTTAPGL 1864

Query: 921  TPLSQAAASIDNRVPTPSSVASAETNSQQPGP 952
                Q +  +D++ PTP +    +  S   GP
Sbjct: 1865 MGTEQLSTELDSKTPTPPAPTLLKMTSSPVGP 1896



 Score = 40.8 bits (94), Expect = 0.016
 Identities = 195/971 (20%), Positives = 312/971 (32%), Gaps = 140/971 (14%)

Query: 80   SSINPGIGNVSAS-SPVQQGLGGQAQGQPNSANMASLSAMGKSPLSQGDSSAPSLPKQAA 138
            S++ PG   +    +P  QG   Q  GQ     M+      + P++   S    +  Q  
Sbjct: 734  SNVMPGPAQIMRGPTPNMQGNMVQFTGQ-----MSGQMLPQQGPVNNSPSQVMGIQGQVL 788

Query: 139  STSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNANFNQTH--PGLLNSNSGHS 196
               GP+P  +Q     A      A +  + SQ  P +    +  QT+  P  + +  G+S
Sbjct: 789  RPPGPSPHMAQQHGDPATT----ANNDVSLSQMMPDV----SIQQTNMVPPHVQAMQGNS 840

Query: 197  LINQASQGQAQVMNGSLGAAGRGR----GAGMPYPTPAMQGASSSVLAETLTQVSPQMTG 252
                   G     N     A  G     G    +P       +S +L   L   S    G
Sbjct: 841  ASGNHFSGHGMSFNAPFSGAPNGNQMSCGQNPGFPVNKDVTLTSPLLVNLLQ--SDISAG 898

Query: 253  HAGLNTAQAGGMAKMGI----------------TGNTSPFGQPFSQAGGQPM-GATGVN- 294
            H G+N  Q    A                    T +T P G    +A   P+ G  G+N 
Sbjct: 899  HFGVNNKQNNTNANKPKKKKPPRKKKNSQQDLNTPDTRPAG--LEEADQPPLPGEQGINL 956

Query: 295  ----PQLASKQSMVNSLPTFPTDIKNTS---------VTNVPNMSQMQTSVGIVPTQAIA 341
                P+L    +     P+ P + +            V   P   Q Q    +   Q   
Sbjct: 957  DNSGPKLPEFSNRPPGYPSQPVEQRPLQQMPPQLMQHVAPPPQPPQQQPQPQLPQQQQ-- 1014

Query: 342  TGPTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAG 401
              P + P+ ++  QQQ  +++     Q  +     V     P    +      M   Q+G
Sbjct: 1015 PPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLNPDSQRMPMQQSG 1074

Query: 402  KACQAI-LGSPAS-----GIQNTIGSVGT--GQQNATSLSNPNPIDPSSMQRAYAALGLP 453
                 + L  PAS       Q     V T  G  +   +   +P +PSS   A  A  LP
Sbjct: 1075 SVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMVYQESPQNPSSSPLAEMA-SLP 1133

Query: 454  YMNQPQTQLQPQVPGQQPAQ---PQTHQQMRTLNPLGNNPMNIPAGGITTDQQPPNLISE 510
              +  +    P  P   P+    PQ    M    P G +P++   G   T QQPP     
Sbjct: 1134 EASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKP-GPSPLSATQGA--TPQQPP----V 1186

Query: 511  SALPTSLGATNPLMNDGSNSGNIGTLSTI-PTAAPPSSTGVRKGWHEHVTQDLRSHLVHK 569
            ++LP+S G   P +   + +    T +   P    P +   R    E     L    ++ 
Sbjct: 1187 NSLPSSHGHHFPNVAAPTQTSRPKTPNRASPRPYYPQTPNNRPPSTEPSEISLSPERLNA 1246

Query: 570  LVQAIFPTPDPAALKDRRMEN------------LVAYAKKVEGDMYESANSRDEYYHLLA 617
             +  +FP      L  R   N            L A  +         +N      H L 
Sbjct: 1247 SIAGLFPPQINIPLPPRPNLNRGFDQQGLNPTTLKAIGQAPSNLTMNPSNFATPQTHKLD 1306

Query: 618  EKIYKIQKELEEKRRSRLHKQGILGNQPA-----LPAPGAQPPVIPQAQPVRPPNGPL-- 670
              +    K+       R        + P       P+PG Q    P+       N  L  
Sbjct: 1307 SVVVNSGKQSNSGATKRASPSNSRRSSPGSSRKTTPSPGRQNSKAPKLTLASQTNAALLQ 1366

Query: 671  --SLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISP 728
               LP N +         +P  L N  +P +       +P N +V + ++G V       
Sbjct: 1367 NVELPRNVL--------VSPTPLANPPVPGSFPNNSGLNPQNSTVSVAAVGGVVEDNKES 1418

Query: 729  SRMPQPPNMMGAHT-----NNMMAQAPAQS--QFLPQNQFPSSSGAMSVGMGQPPAQTGV 781
              +PQ  +   + +     N  +   PAQ     +P++Q            GQP      
Sbjct: 1419 LNVPQDSDCQNSQSRKEQVNIELKAVPAQEVKMVVPEDQSKKD--------GQPS----- 1465

Query: 782  SQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTP 841
               ++P  ++    N++ P   + P            P       G+  L+ T P     
Sbjct: 1466 DPNKLP--SVEENKNLVSPAMREAPTSLSQLLDNSGAPNVTIKPPGLTDLEVTPPVVSGE 1523

Query: 842  PQPAAPTQPSTPVSSSGQTPT-----PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPV 896
                A   P+    SS + P+     P    + S+        V +     + P    PV
Sbjct: 1524 DLKKASVIPTLQDLSSSKEPSNSLNLPHSNELCSSLVHPELSEVSSNVAPSIPPVMSRPV 1583

Query: 897  QPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPT--PSSVASAETNSQQPGPDV 954
               S++TP    Q    V + P  T  + +AA     +PT   S++ S        G  V
Sbjct: 1584 SSSSISTPLPPNQITVFVTSNPITTSANTSAA-----LPTHLQSALMSTVVTMPNAGSKV 1638

Query: 955  PVLEMKTETQA 965
             V E ++  Q+
Sbjct: 1639 MVSEGQSAAQS 1649



 Score = 37.4 bits (85), Expect = 0.18
 Identities = 45/168 (26%), Positives = 59/168 (35%), Gaps = 23/168 (13%)

Query: 1866 QPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQ----PPPAAVEAA 1921
            Q  AQ    P  ++P    S +  Q    V  G   S +PA P        PP  AV   
Sbjct: 1644 QSAAQSNARPQFITPVFINSSSIIQ----VMKGSQPSTIPAAPLTTNSGLMPPSVAVVGP 1699

Query: 1922 RQIEREAQQQQHLYRVNINNSMPPGRTGMGTP---GSQMAPVSLNVPRPNQVSGPVMPSM 1978
              I +  +        N  +S P      G P    S+  PV L  P P   S PV+PS 
Sbjct: 1700 LHIPQNIKFSSAPVPPNALSSSPAPNIQTGRPLVLSSRATPVQL--PSPPCTSSPVVPSH 1757

Query: 1979 PPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISP 2026
            PP Q  +   P +           S Q   +     +PS Q    +SP
Sbjct: 1758 PPVQQVKELNPDE----------ASPQVNTSADQNTLPSSQSTTMVSP 1795


>gi|38158015 mastermind-like 3 [Homo sapiens]
          Length = 1133

 Score = 82.4 bits (202), Expect = 5e-15
 Identities = 139/594 (23%), Positives = 196/594 (32%), Gaps = 108/594 (18%)

Query: 1857 QQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPA 1916
            ++   P+  QP  +   +P+S   A   S     P   VS G P     A P  + PP +
Sbjct: 334  EEKKEPEFSQPATE---TPLSQESASVKSDPSHSPFAHVSMGSP----QARPSSSGPPFS 386

Query: 1917 AVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMP 1976
             V  A  +   A                       TP    AP   + P    V  P  P
Sbjct: 387  TVSTATSLPSVA----------------------STPA---APNPASSPANCAVQSPQTP 421

Query: 1977 SMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTL 2036
            +      Q  P P    +       ++  A   VA P    + P   +   A Q   R  
Sbjct: 422  NQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVP-SSDMSPAEQLKQMAAQQQQRAK 480

Query: 2037 KSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGL-----QSQPGMQP 2091
                  QQQQQ     +   Q        +T+ +    P   P          + P M P
Sbjct: 481  LMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYP 540

Query: 2092 QPGMHQQPSLQNL-NAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHN--------- 2141
            Q   +Q P +  + N +Q       +P     M    P     N +N  HN         
Sbjct: 541  QAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKP 600

Query: 2142 -------------PNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMA 2188
                         P +A  NP    ++    +QQQQQQQQQQQQQQQQQQ          
Sbjct: 601  LTHFNADLSQRMTPPVA--NPNKNPLM--PYIQQQQQQQQQQQQQQQQQQPPPPQLQAPR 656

Query: 2189 GH--------------GQFQQPQGPGGYPPAMQQQQ---------RMQQHLPLQGSSM-- 2223
             H              G   QP      P   Q+Q           MQ  +P     M  
Sbjct: 657  AHLSEDQKRLLLMKQKGVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVS 716

Query: 2224 GQMAAQMGQLGQMGQPGLG----ADSTPNI-----QQALQQRILQQQQMKQQIGSPGQPN 2274
            G   A  G LG   Q  +      D    +     QQ L+++  QQQQ +Q +       
Sbjct: 717  GASPAGPGFLGSQPQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQQ 776

Query: 2275 PMSPQQHMLSGQPQASHLPGQQIATSLSN-----QVRSPAPVQSPRPQSQPPHSSPSPRI 2329
               P+QH+   QPQ +  P QQ+     +      VRS A +QS R       ++    I
Sbjct: 777  SHLPRQHL---QPQRNPYPVQQVNQFQGSPQDIAAVRSQAALQSMRTSRLMAQNAGMMGI 833

Query: 2330 QPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSALS 2383
             P  +P  ++        GLA    +   Q  + N   + M   L  P++S +S
Sbjct: 834  GPSQNPGTMATAAAQSEMGLAPYSTTPTSQPGMYN-MSTGMTQMLQHPNQSGMS 886



 Score = 79.0 bits (193), Expect = 5e-14
 Identities = 139/593 (23%), Positives = 205/593 (34%), Gaps = 116/593 (19%)

Query: 1845 PSPTSAPPGTPTQQPSTPQTPQPPAQPQP--------SPVSMSPAGFPSVARTQPPTTVS 1896
            P+P S+P     Q P TP     P Q  P        +P +++ AG  S     P + +S
Sbjct: 404  PNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASGPVAVPSSDMS 463

Query: 1897 TGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQ 1956
              +   Q+ A            +  +Q +++ QQQQ   +   +++     + +G P S 
Sbjct: 464  PAEQLKQMAAQQQQRAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSP 523

Query: 1957 MAPVSLNVPRPNQV---------SGPVMPSMPPGQWQQAP---LPQ-------QQPMPGL 1997
                +    +PN             P++P M     +      LPQ       QQP   L
Sbjct: 524  YG-AAFTAEKPNSPMMYPQAFNNQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPN-NL 581

Query: 1998 PRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSP----------QQQQQ 2047
                ++ Q      G   P       +S      +    K+P  P          QQQQQ
Sbjct: 582  GTNSLNKQHNILTYGNTKPLTHFNADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQ 641

Query: 2048 VLNILKSNPQLMA--AFIKQRTAKYVANQPGMQPQPGLQSQP---GMQPQPGMHQQPS-- 2100
                    PQL A  A + +   + +     +  Q G+ +QP      P  G  Q P   
Sbjct: 642  QQQQQPPPPQLQAPRAHLSEDQKRLL-----LMKQKGVMNQPMAYAALPSHGQEQHPVGL 696

Query: 2101 LQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLL 2160
             +    MQ+ VP    P     + G +P G        G  P  A M     +  R QL+
Sbjct: 697  PRTTGPMQSSVP----PGSGGMVSGASPAGPGFL----GSQPQAAIMKQMLIDQ-RAQLI 747

Query: 2161 QQQQQQ--QQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPL 2218
            +QQ+QQ  ++Q+QQQQQQQQ                           + +QQ  Q HLP 
Sbjct: 748  EQQKQQFLREQRQQQQQQQQ--------------------------ILAEQQLQQSHLPR 781

Query: 2219 QGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSP 2278
            Q     +    + Q+ Q    G   D      QA  Q +   + M Q  G  G    + P
Sbjct: 782  QHLQPQRNPYPVQQVNQF--QGSPQDIAAVRSQAALQSMRTSRLMAQNAGMMG----IGP 835

Query: 2279 QQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPS---------PRI 2329
             Q+           PG  +AT+ +      AP  S  P SQP   + S         P  
Sbjct: 836  SQN-----------PG-TMATAAAQSEMGLAP-YSTTPTSQPGMYNMSTGMTQMLQHPNQ 882

Query: 2330 QPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSAL 2382
                  H+ +     P  G  V M S   Q  L N   +   PQ+  P   AL
Sbjct: 883  SGMSITHNQAQGPRQPASGQGVGMVSGFGQSMLVNSAITQQHPQMKGPVGQAL 935



 Score = 69.3 bits (168), Expect = 4e-11
 Identities = 149/677 (22%), Positives = 226/677 (33%), Gaps = 166/677 (24%)

Query: 1813 RQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAP---------PGTPTQQPSTPQ 1863
            +QQQ Q + QQ Q  +++    ++      S   P S+P         P +P   P    
Sbjct: 485  KQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFN 544

Query: 1864 TPQPPAQPQPSPVSMS------PAGFPSVARTQPPT-------------TVSTGKPTSQV 1904
               P   P  + +  +      P    ++   QP               T    KP +  
Sbjct: 545  NQNPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKPLTHF 604

Query: 1905 PA------PPPPA----------------------------QPPPAAVEAARQIEREAQQ 1930
             A       PP A                            QPPP  ++A R    E Q+
Sbjct: 605  NADLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSEDQK 664

Query: 1931 QQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQW------- 1983
            +  L +     + P     + + G +  PV L  PR    +GP+  S+PPG         
Sbjct: 665  RLLLMKQKGVMNQPMAYAALPSHGQEQHPVGL--PR---TTGPMQSSVPPGSGGMVSGAS 719

Query: 1984 ---------QQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQD--L 2032
                     Q      +Q +      +I  Q Q  +   R    Q  + ++   LQ   L
Sbjct: 720  PAGPGFLGSQPQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQILAEQQLQQSHL 779

Query: 2033 LRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQ------RTAKYVANQPGM-----QPQP 2081
             R    P       Q +N  + +PQ +AA   Q      RT++ +A   GM        P
Sbjct: 780  PRQHLQPQRNPYPVQQVNQFQGSPQDIAAVRSQAALQSMRTSRLMAQNAGMMGIGPSQNP 839

Query: 2082 G------LQSQPGMQP-------QPGMH----------QQPSLQNLNAMQAGVPRPGVPP 2118
            G       QS+ G+ P       QPGM+          Q P+   ++        P  P 
Sbjct: 840  GTMATAAAQSEMGLAPYSTTPTSQPGMYNMSTGMTQMLQHPNQSGMSITHNQAQGPRQPA 899

Query: 2119 QQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQ-------QQQQ 2171
              Q +G ++  GQ++ +     N  +   +PQ +  + + L + Q   +        QQ 
Sbjct: 900  SGQGVGMVSGFGQSMLV-----NSAITQQHPQMKGPVGQALPRPQAPPRLQSLMGTVQQG 954

Query: 2172 QQQQQQQGSAGMAGGMAGH-GQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQM 2230
             Q  QQ+   GM G  +G  G F        YP    Q +  +QH P QG S   + A  
Sbjct: 955  AQSWQQRSLQGMPGRTSGELGPF---NNGASYPLQAGQPRLTKQHFP-QGLSQSVVDANT 1010

Query: 2231 GQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQAS 2290
            G +  +    +G    P++               QQ  S  +P  MS     + G P  S
Sbjct: 1011 GTVRTLNPAAMGRQMMPSLP-------------GQQGTSQARPMVMSGLSQGVPGMPAFS 1057

Query: 2291 HLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQ-TGSPHPGL 2349
              P QQ             P  S  P SQ   S    R  PQ   ++ S    G   PGL
Sbjct: 1058 QPPAQQ-----------QIPSGSFAPSSQ---SQAYERNAPQDVSYNYSGDGAGGSFPGL 1103

Query: 2350 --AVTMASSIDQGHLGN 2364
                 +  SI +G  G+
Sbjct: 1104 PDGADLVDSIIKGGPGD 1120



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 113/515 (21%), Positives = 180/515 (34%), Gaps = 76/515 (14%)

Query: 452  LPYMNQPQTQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQQPPNLISES 511
            +PY+ Q Q Q Q Q   QQ  QP   Q            +  P   ++ DQ+   L+ + 
Sbjct: 625  MPYIQQQQQQQQQQQQQQQQQQPPPPQ------------LQAPRAHLSEDQKRLLLMKQK 672

Query: 512  ALPTSLGATNPLMNDGSNSGNIG---TLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVH 568
             +     A   L + G     +G   T   + ++ PP S G+  G        L S    
Sbjct: 673  GVMNQPMAYAALPSHGQEQHPVGLPRTTGPMQSSVPPGSGGMVSGASPAGPGFLGSQ--- 729

Query: 569  KLVQAIFPTPDPAALKDRRMENLVAYAKKVEGD-MYESANSRDEYYHLLAEKIYKIQKEL 627
                     P  A +K   ++      ++ +   + E    + +   +LAE      ++L
Sbjct: 730  ---------PQAAIMKQMLIDQRAQLIEQQKQQFLREQRQQQQQQQQILAE------QQL 774

Query: 628  EEKRRSRLHKQGILGNQPALPAPGAQPPVIPQ-AQPVRPPNGPLSLPVNRMQVSQGMNSF 686
            ++    R H Q      P       Q    PQ    VR      S+  +R+         
Sbjct: 775  QQSHLPRQHLQPQRNPYPVQQVNQFQGS--PQDIAAVRSQAALQSMRTSRLMAQNA---- 828

Query: 687  NPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPG---MAISPSRMPQPPNMMGAHTN 743
              M +G  Q P       A S M  +    +  S PG   M+   ++M Q PN  G    
Sbjct: 829  GMMGIGPSQNPGTMATAAAQSEMGLAPYSTTPTSQPGMYNMSTGMTQMLQHPNQSGMSIT 888

Query: 744  NMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNP-LNMLGPQA 802
            +  AQ P Q         P+S     VGM      +G  Q  +  +A+      M GP  
Sbjct: 889  HNQAQGPRQ---------PAS--GQGVGM-----VSGFGQSMLVNSAITQQHPQMKGPVG 932

Query: 803  SQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSS----SG 858
              LP P   Q+P        +   G  S Q  +  GM P + +    P    +S    +G
Sbjct: 933  QALPRP---QAPPRLQSLMGTVQQGAQSWQQRSLQGM-PGRTSGELGPFNNGASYPLQAG 988

Query: 859  Q---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVH 915
            Q   T    P  +  +    +T TV+    A +  Q   P  P    T Q+     + + 
Sbjct: 989  QPRLTKQHFPQGLSQSVVDANTGTVRTLNPAAMGRQ-MMPSLPGQQGTSQARPMVMSGLS 1047

Query: 916  AQPPGTP-LSQAAASIDNRVPTPSSVASAETNSQQ 949
               PG P  SQ  A    ++P+ S   S+++ + +
Sbjct: 1048 QGVPGMPAFSQPPA--QQQIPSGSFAPSSQSQAYE 1080



 Score = 41.2 bits (95), Expect = 0.012
 Identities = 53/252 (21%), Positives = 94/252 (37%), Gaps = 50/252 (19%)

Query: 820  PPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPT 879
            P   T     S    + P  +P    +   P    SSSG    P   +V +AT   S  +
Sbjct: 344  PATETPLSQESASVKSDPSHSPFAHVSMGSPQARPSSSG----PPFSTVSTATSLPSVAS 399

Query: 880  VQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQP-PGTP--LSQAAASIDNRVPT 936
              AA      P P +     +V +PQ+  Q  TP  A P PG    L+ AA ++      
Sbjct: 400  TPAA------PNPASSPANCAVQSPQTPNQAHTPGQAPPRPGNGYLLNPAAVTVAGSASG 453

Query: 937  PSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKE 996
            P +V S++ +        P  ++K                            Q A+Q ++
Sbjct: 454  PVAVPSSDMS--------PAEQLK----------------------------QMAAQQQQ 477

Query: 997  ETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQAL 1056
               + +QK +  +  +++ + + + ++++ S+     S    PS P    F  E+    +
Sbjct: 478  RAKLMQQKQQQQQQQQQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPM 537

Query: 1057 MPTLEALYRQDP 1068
            M   +A   Q+P
Sbjct: 538  MYP-QAFNNQNP 548



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 69/295 (23%), Positives = 97/295 (32%), Gaps = 34/295 (11%)

Query: 658 PQAQPVR--PPNGPLSLPVNRMQVSQGMNSFNPMSLGN---VQLPQAPM-----GPRAAS 707
           PQA+P    PP   +S   +   V+    + NP S      VQ PQ P      G     
Sbjct: 374 PQARPSSSGPPFSTVSTATSLPSVASTPAAPNPASSPANCAVQSPQTPNQAHTPGQAPPR 433

Query: 708 PMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGA 767
           P N  +   +  +V G A  P  +P            M AQ   +++ + Q Q       
Sbjct: 434 PGNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQKQQQQQQQ- 492

Query: 768 MSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAG 827
                 Q   Q    Q Q   +   +  + LGP +S        + P  P   P +    
Sbjct: 493 ------QQQQQQQQQQQQQQHSNQTSNWSPLGPPSSPYGAAFTAEKPNSPMMYPQAFNNQ 546

Query: 828 MP-------SLQHTTPPGMTPPQPA--APTQPSTPVSSS--GQTPTPTPGSVPSATQTQS 876
            P       +LQ TT     P         QP+   ++S   Q    T G+    T   +
Sbjct: 547 NPIVPPMANNLQKTTMNNYLPQNHMNMINQQPNNLGTNSLNKQHNILTYGNTKPLTHFNA 606

Query: 877 ------TPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQ 925
                 TP V    +  + P  Q   Q       Q  QQQP P   Q P   LS+
Sbjct: 607 DLSQRMTPPVANPNKNPLMPYIQQQQQQQQQQQQQQQQQQPPPPQLQAPRAHLSE 661



 Score = 33.1 bits (74), Expect = 3.4
 Identities = 60/252 (23%), Positives = 83/252 (32%), Gaps = 37/252 (14%)

Query: 84  PGIGNVSASSPVQQGLGGQAQGQPNSANMASLSAMGKSPLSQGDSSAP---------SLP 134
           P     +  +P+ Q      +  P+ +  A +S MG SP ++  SS P         SLP
Sbjct: 339 PEFSQPATETPLSQE-SASVKSDPSHSPFAHVS-MG-SPQARPSSSGPPFSTVSTATSLP 395

Query: 135 KQAASTSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNANFNQTH-PGLLNSNS 193
             A++ + P PA+S A           A  SP T             NQ H PG      
Sbjct: 396 SVASTPAAPNPASSPA---------NCAVQSPQTP------------NQAHTPGQAPPRP 434

Query: 194 GHS-LINQASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLAETLTQVSPQMTG 252
           G+  L+N A+   A   +G +                A Q    + L +   Q   Q   
Sbjct: 435 GNGYLLNPAAVTVAGSASGPVAVPSSDMSPAEQLKQMAAQQQQRAKLMQQ-KQQQQQQQQ 493

Query: 253 HAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASKQSMVNSLPTFPT 312
                  Q         T N SP G P S   G    A   N  +   Q+  N  P  P 
Sbjct: 494 QQQQQQQQQQQQQHSNQTSNWSPLGPP-SSPYGAAFTAEKPNSPMMYPQAFNNQNPIVPP 552

Query: 313 DIKNTSVTNVPN 324
              N   T + N
Sbjct: 553 MANNLQKTTMNN 564


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 82/336 (24%), Positives = 116/336 (34%), Gaps = 25/336 (7%)

Query: 648  PAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAAS 707
            P     PP      P  PP    S P+             P +  +  +      P   +
Sbjct: 1418 PTTTPSPPTTTTTTP--PPTTTPSPPITTTTTPP------PTTTPSPPISTTTTPPPTTT 1469

Query: 708  PMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGA 767
            P   +   +   + P    + +  P P       T   +   PA +  LP    PS    
Sbjct: 1470 PSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP-PASTTTLPPTTTPSPPTT 1528

Query: 768  MSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPP--PASTA 825
             +     PP  T  S         P     L P  +  P P  T +P   T P  P +T 
Sbjct: 1529 TTT---TPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTT 1585

Query: 826  AGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQT-QSTPTVQAAA 884
               P++  TTPP  T P P   T  + P +++   PT TP + P++T T   T T     
Sbjct: 1586 PSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPP 1645

Query: 885  QAQVTPQPQTPVQPPSVATPQ-----SSQQQPTPVHAQPPGTPLSQAAASIDNRVP--TP 937
                TP P T   PP+  TP      ++   PT   + P  T  S    ++    P  TP
Sbjct: 1646 TTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTP 1705

Query: 938  SS-VASAETNSQQPGPDVPVLEMKTETQAEDTEPDP 972
            SS + +  T S    P  P   M T +    T P P
Sbjct: 1706 SSPITTTTTPSSTTTPSPPPTTMTTPSPT--TTPSP 1739



 Score = 67.8 bits (164), Expect = 1e-10
 Identities = 51/197 (25%), Positives = 68/197 (34%), Gaps = 12/197 (6%)

Query: 1836 TRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQ--PPAQPQPSPVSMSPAGFPSVARTQPPT 1893
            T   P  + PSP +  P  PT  PS P T    PP    PSP + +P   P+   T PPT
Sbjct: 1461 TTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPT 1520

Query: 1894 TVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTP 1953
            T +   PT+    PPP   P P                          S PP  T    P
Sbjct: 1521 T-TPSPPTTTTTTPPPTTTPSPPTTTPI-----TPPTSTTTLPPTTTPSPPPTTTTTPPP 1574

Query: 1954 GSQMAPVSLNVPRPNQVS----GPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAA 2009
             +  +P +   P P  ++     P     PP      P P   P P    P+    +   
Sbjct: 1575 TTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTT 1634

Query: 2010 VAGPRMPSVQPPRSISP 2026
            +     PS  P  + +P
Sbjct: 1635 LPPTTTPSPPPTTTTTP 1651



 Score = 67.0 bits (162), Expect = 2e-10
 Identities = 49/174 (28%), Positives = 69/174 (39%), Gaps = 15/174 (8%)

Query: 806  PCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTP 865
            P PP T     P+PPP ST   +P     +PP  T   P   T PS P++++   P  T 
Sbjct: 1399 PSPPTTT----PSPPPTSTTT-LPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTT 1453

Query: 866  GSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQ 925
             S P +T T   PT      +  T  P  P   PS  T  ++   PT   + P  TP++ 
Sbjct: 1454 PSPPISTTTTPPPT---TTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP 1510

Query: 926  AAA------SIDNRVPTPSSVASAETNSQQPGPDVPVL-EMKTETQAEDTEPDP 972
             A+      +     PT ++     T +  P    P+     T T    T P P
Sbjct: 1511 PASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSP 1564



 Score = 65.9 bits (159), Expect = 5e-10
 Identities = 54/207 (26%), Positives = 74/207 (35%), Gaps = 18/207 (8%)

Query: 776  PAQTGVSQGQVPGAALPNP--LNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQH 833
            P+    S   +P    P+P       P  +  P PP+T +    T PP +T    P    
Sbjct: 1406 PSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTT----TTPPPTTTPSPPISTT 1461

Query: 834  TTPPGMTPPQP-----AAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQV 888
            TTPP  T P P     + PT   +P +++  TP PT    P  T   + P          
Sbjct: 1462 TTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTT 1521

Query: 889  TPQP--QTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETN 946
            TP P   T   PP   TP      PT     PP +  +    +  +  PT ++     T 
Sbjct: 1522 TPSPPTTTTTTPPPTTTP----SPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTT 1577

Query: 947  SQQPGPDVP-VLEMKTETQAEDTEPDP 972
               P    P    + T T    T P P
Sbjct: 1578 PSPPTTTTPSPPTITTTTPPPTTTPSP 1604



 Score = 65.5 bits (158), Expect = 6e-10
 Identities = 65/304 (21%), Positives = 100/304 (32%), Gaps = 23/304 (7%)

Query: 645  PALPAPGAQPPVI------PQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQ 698
            P+ P     PP        P   P  P   P++ P +   +        P +      P 
Sbjct: 1477 PSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPT 1536

Query: 699  APMGPRAASPMNHSVQMNSMG--SVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFL 756
                P   +P+       ++   + P    + +  P P       T    +     +   
Sbjct: 1537 TTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTP 1596

Query: 757  PQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLH 816
            P    PS     +     PP  T  S         P     L P  +  P P  T     
Sbjct: 1597 PPTTTPSPPTTTTT---TPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTT----- 1648

Query: 817  PTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQS 876
             T PP +T    P+    +PP  T   P   T PS+P++++   PT T  + PS T T S
Sbjct: 1649 -TTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTM-TTPSPTTTPS 1706

Query: 877  TPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPT 936
            +P       +  T    TP  PP+  T  S    P+P        P +  ++ +    P 
Sbjct: 1707 SPITTTTTPSSTT----TPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPL-TTTPL 1761

Query: 937  PSSV 940
            P S+
Sbjct: 1762 PPSI 1765



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 73/332 (21%), Positives = 107/332 (32%), Gaps = 41/332 (12%)

Query: 650  PGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQA-PMGPRAASP 708
            P    P  P   P+ PP    +LP           +  P        P   P+ P  ++ 
Sbjct: 1495 PPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTT 1554

Query: 709  MNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAM 768
                    S          P+  P PP         +    P  +   P     +++   
Sbjct: 1555 TLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTT-TPSPPTTTTTTPP 1613

Query: 769  SVGMGQPPAQTGV----SQGQVPGAALPNP--LNMLGPQASQLPCPPVTQSPLHP----T 818
                  PP  T +    S   +P    P+P       P  +  P PP T +P  P    T
Sbjct: 1614 PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTT 1673

Query: 819  PPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVS-----SSGQTP--------TPTP 865
             PP +T    P     +PP  T   P+  T PS+P++     SS  TP        TP+P
Sbjct: 1674 TPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSP 1733

Query: 866  GSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQ 925
             + PS   T  T        + +T  P  P   P   +P S+    TP        PL  
Sbjct: 1734 TTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPC------VPLCN 1787

Query: 926  AAASIDNRVPTPSSVASAETNSQQPGPDVPVL 957
                +D          S + N  +PG D  ++
Sbjct: 1788 WTGWLD----------SGKPNFHKPGGDTELI 1809



 Score = 62.0 bits (149), Expect = 7e-09
 Identities = 51/218 (23%), Positives = 76/218 (34%), Gaps = 38/218 (17%)

Query: 1845 PSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQV 1904
            P+ T +PP T T  P    TP PP    PSP +++    P      PPTT +T  P +  
Sbjct: 1558 PTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTT 1617

Query: 1905 PAPP--PPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSL 1962
            P+PP   P  PP +                         ++PP  T    P +   P   
Sbjct: 1618 PSPPTTTPITPPTS-----------------------TTTLPPTTTPSPPPTTTTTPPPT 1654

Query: 1963 NVPRPNQVSGPVMP-----SMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMP- 2016
              P P   + P  P     + PP     +P+    P P    P  +M   +    P  P 
Sbjct: 1655 TTPSPPTTTTPSPPITTTTTPPPTTTPSSPI-TTTPSP----PTTTMTTPSPTTTPSSPI 1709

Query: 2017 --SVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNIL 2052
              +  P  + +PS     + T    ++P      +  L
Sbjct: 1710 TTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTL 1747



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 1913 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 1972

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 1973 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 2029

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2030 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2084



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 1959 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2018

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 2019 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 2075

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2076 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2130



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 2028 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2087

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 2088 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 2144

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2145 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2199



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 2097 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2156

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 2157 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 2213

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2214 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2268



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 2166 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2225

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 2226 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 2282

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2283 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2337



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 2235 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2294

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 2295 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 2351

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2352 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2406



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 2304 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2363

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 2364 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 2420

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2421 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2475



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 2373 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2432

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 2433 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 2489

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2490 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2544



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 2442 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2501

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 2502 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 2558

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2559 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2613



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 2511 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2570

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 2571 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 2627

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2628 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2682



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 2580 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2639

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 2640 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 2696

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2697 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2751



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 2649 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2708

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 2709 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 2765

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2766 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2820



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 2718 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2777

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 2778 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 2834

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2835 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2889



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 2787 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2846

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 2847 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 2903

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2904 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2958



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 2856 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2915

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 2916 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 2972

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2973 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3027



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 2925 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2984

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 2985 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 3041

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3042 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3096



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 2994 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3053

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 3054 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 3110

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3111 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3165



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 3063 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3122

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 3123 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 3179

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3180 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3234



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 3132 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3191

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 3192 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 3248

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3249 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3303



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 3201 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3260

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 3261 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 3317

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3318 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3372



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 3270 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3329

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 3330 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 3386

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3387 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3441



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 3339 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3398

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 3399 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 3455

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3456 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3510



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 3408 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3467

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 3468 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 3524

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3525 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3579



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 3477 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3536

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 3537 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 3593

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3594 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3648



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 3546 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3605

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 3606 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 3662

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3663 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3717



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 3615 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3674

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 3675 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 3731

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3732 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3786



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 3684 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3743

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 3744 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 3800

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3801 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3855



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 3753 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3812

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 3813 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 3869

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3870 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3924



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 3822 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3881

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 3882 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 3938

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3939 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3993



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 3891 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3950

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 3951 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 4007

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 4008 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4062



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 50/176 (28%), Positives = 66/176 (37%), Gaps = 9/176 (5%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 3960 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4019

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 4020 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 4076

Query: 915  HAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
              Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 4077 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4131



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 64/259 (24%), Positives = 90/259 (34%), Gaps = 24/259 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T     +   TT      P P     P+T   ++
Sbjct: 4029 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4088

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPV 914
              T TPTP   P+ TQT +T  +        TP P   QTP   P + T  +    PTP 
Sbjct: 4089 TTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPT 4145

Query: 915  HAQ-PPGTPLSQAAASIDNRVP----TPSSVASAETNSQQPGPDV------PVLEMKTET 963
              Q P  TP++          P    TP++     T +  P P        P     T  
Sbjct: 4146 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAP 4205

Query: 964  QAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKE 1023
             AE T  +P      P S   +     +S + E T +       +E+    P        
Sbjct: 4206 IAELTTSNP-----PPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPT 4260

Query: 1024 EEESSSNGTASQSTSPSQP 1042
                    +   ST+ S P
Sbjct: 4261 TTSGGHTLSPPPSTTTSPP 4279



 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 47/166 (28%), Positives = 62/166 (37%), Gaps = 7/166 (4%)

Query: 808  PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGS 867
            P  T + + PTP P  T     +   TT      P P     P+T   ++  T TPTP  
Sbjct: 1900 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-- 1957

Query: 868  VPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQPTPVHAQPPGTPLS 924
             P+ TQT +T  +        TP P   QTP   P + T  +    PTP   Q P T   
Sbjct: 1958 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPI 2016

Query: 925  QAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
                ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2017 TTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2061



 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 47/155 (30%), Positives = 67/155 (43%), Gaps = 12/155 (7%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS 857
            P  +Q P   P  T + + PTP P  T  G P+  HT+    T P     T    P SS+
Sbjct: 4167 PTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPT--HTS----TAPIAELTTSNPPPESST 4220

Query: 858  GQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQ 917
             QT   T  S P    T    T+  A +   T  P TP  P + +   +    P+     
Sbjct: 4221 PQTSRST--SSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTT-TS 4277

Query: 918  PPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGP 952
            PPGTP ++   +  +  PTPS+V +  T++  P P
Sbjct: 4278 PPGTP-TRGTTTGSSSAPTPSTVQTTTTSAWTPTP 4311



 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 51/211 (24%), Positives = 70/211 (33%), Gaps = 30/211 (14%)

Query: 1833 TMNTRNVPQQSLPSPTSAPPGTP-----------TQQPSTPQTPQPPAQPQPSPVSMSPA 1881
            T  T   P  + PSP +  P TP           T  P T  T  PP    PSP + +P 
Sbjct: 1488 TTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1547

Query: 1882 GFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINN 1941
              P+   T PPTT  +  PT+    PP     PP     +                 I  
Sbjct: 1548 TPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPP--------------TITT 1593

Query: 1942 SMPPGRTGMGTP-GSQMAPVSLNVPRP---NQVSGPVMPSMPPGQWQQAPLPQQQPMPGL 1997
            + PP  T    P  +   P     P P     ++ P   +  P     +P P     P  
Sbjct: 1594 TTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPP- 1652

Query: 1998 PRPVISMQAQAAVAGPRMPSVQPPRSISPSA 2028
            P    S       + P   +  PP + +PS+
Sbjct: 1653 PTTTPSPPTTTTPSPPITTTTTPPPTTTPSS 1683



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 1936 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 1995

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 1996 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 2048

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2049 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2107



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 1982 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2041

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 2042 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 2094

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2095 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2153



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 2005 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2064

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 2065 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 2117

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2118 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2176



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 2051 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2110

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 2111 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 2163

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2164 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2222



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 2074 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2133

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 2134 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 2186

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2187 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2245



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 2120 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2179

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 2180 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 2232

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2233 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2291



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 2143 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2202

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 2203 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 2255

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2256 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2314



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 2189 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2248

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 2249 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 2301

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2302 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2360



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 2212 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2271

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 2272 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 2324

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2325 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2383



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 2258 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2317

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 2318 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 2370

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2371 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2429



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 2281 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2340

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 2341 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 2393

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2394 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2452



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 2327 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2386

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 2387 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 2439

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2440 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2498



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 2350 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2409

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 2410 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 2462

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2463 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2521



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 2396 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2455

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 2456 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 2508

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2509 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2567



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 2419 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2478

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 2479 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 2531

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2532 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2590



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 2465 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2524

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 2525 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 2577

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2578 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2636



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 2488 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2547

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 2548 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 2600

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2601 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2659



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 2534 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2593

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 2594 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 2646

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2647 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2705



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 2557 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2616

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 2617 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 2669

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2670 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2728



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 2603 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2662

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 2663 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 2715

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2716 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2774



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 2626 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2685

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 2686 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 2738

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2739 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2797



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 2672 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2731

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 2732 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 2784

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2785 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2843



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 2695 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2754

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 2755 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 2807

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2808 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2866



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 2741 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2800

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 2801 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 2853

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2854 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2912



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 2764 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2823

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 2824 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 2876

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2877 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2935



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 2810 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2869

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 2870 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 2922

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2923 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2981



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 2833 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2892

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 2893 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 2945

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2946 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3004



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 2879 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2938

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 2939 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 2991

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 2992 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3050



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 2902 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2961

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 2962 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 3014

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3015 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3073



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 2948 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3007

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 3008 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 3060

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3061 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3119



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 2971 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3030

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 3031 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 3083

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3084 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3142



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 3017 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3076

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 3077 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 3129

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3130 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3188



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 3040 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3099

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 3100 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 3152

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3153 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3211



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 3086 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3145

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 3146 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 3198

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3199 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3257



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 3109 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3168

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 3169 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 3221

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3222 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3280



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 3155 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3214

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 3215 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 3267

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3268 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3326



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 3178 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3237

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 3238 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 3290

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3291 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3349



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 3224 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3283

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 3284 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 3336

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3337 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3395



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 3247 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3306

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 3307 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 3359

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3360 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3418



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 3293 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3352

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 3353 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 3405

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3406 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3464



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 3316 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3375

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 3376 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 3428

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3429 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3487



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 3362 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3421

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 3422 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 3474

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3475 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3533



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 3385 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3444

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 3445 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 3497

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3498 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3556



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 3431 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3490

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 3491 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 3543

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3544 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3602



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 3454 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3513

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 3514 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 3566

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3567 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3625



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 3500 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3559

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 3560 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 3612

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3613 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3671



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 3523 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3582

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 3583 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 3635

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3636 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3694



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 3569 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3628

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 3629 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 3681

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3682 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3740



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 3592 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3651

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 3652 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 3704

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3705 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3763



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 3638 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3697

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 3698 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 3750

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3751 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3809



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 3661 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3720

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 3721 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 3773

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3774 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3832



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 3707 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3766

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 3767 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 3819

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3820 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3878



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 3730 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3789

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 3790 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 3842

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3843 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3901



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 3776 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3835

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 3836 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 3888

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3889 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3947



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 3799 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3858

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 3859 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 3911

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3912 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3970



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 3845 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3904

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 3905 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 3957

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3958 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4016



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 3868 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3927

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 3928 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 3980

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 3981 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4039



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 3914 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3973

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 3974 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 4026

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 4027 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4085



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 3937 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3996

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 3997 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 4049

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 4050 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4108



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 3983 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4042

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 4043 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 4095

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 4096 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4154



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 51/180 (28%), Positives = 69/180 (38%), Gaps = 17/180 (9%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 4006 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4065

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP---QTPVQPPSVATPQSSQQQ 910
            +     TPTPT    P+ T   +T TV        TP P   QTP   P + T  +    
Sbjct: 4066 TTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP-ITTTTTVTPT 4118

Query: 911  PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEP 970
            PTP   Q P T       ++    PTP+   +  T        V      T TQ   T P
Sbjct: 4119 PTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4177



 Score = 54.7 bits (130), Expect = 1e-06
 Identities = 43/184 (23%), Positives = 57/184 (30%), Gaps = 11/184 (5%)

Query: 1843 SLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTS 1902
            S P+ T +PP T T       TP PP     +P   +    P    T PP T +   P S
Sbjct: 1400 SPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPIS 1459

Query: 1903 QVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSL 1962
                PPP   P P     +      +             + PP  T   TP S      +
Sbjct: 1460 TTTTPPPTTTPSPPTTTPSPPTTTPSPP-------TTTTTTPPPTT---TP-SPPTTTPI 1508

Query: 1963 NVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPR 2022
              P       P     PP      P P   P P    P+    +   +     PS  P  
Sbjct: 1509 TPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTT 1568

Query: 2023 SISP 2026
            + +P
Sbjct: 1569 TTTP 1572



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 53/199 (26%), Positives = 74/199 (37%), Gaps = 22/199 (11%)

Query: 782  SQGQVPGAALPNP------LNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHT- 834
            ++ Q PG  +P        +N+   +    P    T +  +PTPP  +      ++  T 
Sbjct: 1852 NEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTP 1911

Query: 835  TPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQP-- 892
            TP G   P     T P T  ++   TPTPT    P+ T   +T TV        TP P  
Sbjct: 1912 TPTGTQTPT----TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTG 1961

Query: 893  -QTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPG 951
             QTP   P + T  +    PTP   Q P T       ++    PTP+   +  T      
Sbjct: 1962 TQTPTTTP-ITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTT 2019

Query: 952  PDVPVLEMKTETQAEDTEP 970
              V      T TQ   T P
Sbjct: 2020 TTVTPTPTPTGTQTPTTTP 2038



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 43/190 (22%), Positives = 62/190 (32%), Gaps = 17/190 (8%)

Query: 1833 TMNTRNVPQQSLPSPTSAPPGTPTQQPST---PQTPQPPAQPQPSPVSMSPAGFPSVART 1889
            T  T   P  + PSP +  P TP    +T     TP PP     +P   +    P+    
Sbjct: 1606 TTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTP 1665

Query: 1890 QPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTG 1949
             PP T +T  P +  P+ P    P P                       I  +  P  T 
Sbjct: 1666 SPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSP------ITTTTTPSSTT 1719

Query: 1950 MGTPGSQMAPVSLNVPRPNQVSGP---VMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQA 2006
              +P     P ++  P P     P    M ++PP     +PL      P +  P  S  +
Sbjct: 1720 TPSP----PPTTMTTPSPTTTPSPPTTTMTTLPP-TTTSSPLTTTPLPPSITPPTFSPFS 1774

Query: 2007 QAAVAGPRMP 2016
                  P +P
Sbjct: 1775 TTTPTTPCVP 1784



 Score = 48.9 bits (115), Expect = 6e-05
 Identities = 50/193 (25%), Positives = 73/193 (37%), Gaps = 26/193 (13%)

Query: 800  PQASQLPC--PPVTQSPLHPTPPPASTAAGMPS-LQHTTPPGMTPPQPAAPTQPSTPVSS 856
            P  +Q P   P  T + + PTP P  T     + +  TT    TP      T  +TP+++
Sbjct: 4098 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4157

Query: 857  SGQ---TPTPTPGSVPSATQTQSTPTV---------QAAAQAQVTPQP----QTPVQPPS 900
            +     TPTPT    P+ T   +T TV         Q       +  P     T   PP 
Sbjct: 4158 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPE 4217

Query: 901  VATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQ-----QPGPDVP 955
             +TPQ+S+   +P+      T LS    +I+     P S  +A T +       P P   
Sbjct: 4218 SSTPQTSRSTSSPLTEST--TLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTT 4275

Query: 956  VLEMKTETQAEDT 968
                 T T+   T
Sbjct: 4276 TSPPGTPTRGTTT 4288



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 33/88 (37%), Positives = 39/88 (44%), Gaps = 6/88 (6%)

Query: 789  AALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPT 848
            + LP  + M        P  P T S  H   PP ST    P    T   G T    +APT
Sbjct: 4239 STLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPG---TPTRGTTTGSSSAPT 4295

Query: 849  QPST--PVSSSGQTPTPTPGSVPSATQT 874
             PST    ++S  TPTPTP S PS  +T
Sbjct: 4296 -PSTVQTTTTSAWTPTPTPLSTPSIIRT 4322



 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 39/141 (27%), Positives = 51/141 (36%), Gaps = 18/141 (12%)

Query: 839  MTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAA--AQAQVTPQPQTPV 896
            +T P P   T    P S++   PT TP S P+ T T   PT   +       TP P T  
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTP-SPPTTTTTTPPPTTTPSPPITTTTTPPPTTTP 1454

Query: 897  QPPSVAT----PQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGP 952
             PP   T    P ++   PT   + P  TP            PT ++     T +  P  
Sbjct: 1455 SPPISTTTTPPPTTTPSPPTTTPSPPTTTP----------SPPTTTTTTPPPTTTPSPPT 1504

Query: 953  DVPVL-EMKTETQAEDTEPDP 972
              P+     T T    T P P
Sbjct: 1505 TTPITPPASTTTLPPTTTPSP 1525



 Score = 45.1 bits (105), Expect = 9e-04
 Identities = 46/146 (31%), Positives = 62/146 (42%), Gaps = 16/146 (10%)

Query: 775  PPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSP-LHPTPPPA----STAA-GM 828
            PP  T  +       + P P +   PQ S+    P+T+S  L  T PPA    STA    
Sbjct: 4197 PPTHTSTAPIAELTTSNPPPESST-PQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPST 4255

Query: 829  PSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQV 888
            P+   TT  G T   P     PST  S  G   TPT G+   ++   +  TVQ    +  
Sbjct: 4256 PTAPTTTSGGHTLSPP-----PSTTTSPPG---TPTRGTTTGSSSAPTPSTVQTTTTSAW 4307

Query: 889  TPQPQTPVQPPSVATPQSSQQQPTPV 914
            TP P TP+  PS+      +  P+ V
Sbjct: 4308 TPTP-TPLSTPSIIRTTGLRPYPSSV 4332



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 36/140 (25%), Positives = 51/140 (36%), Gaps = 11/140 (7%)

Query: 1776 GGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRLQQAQLMRRRMATMN 1835
            G   VC   + L C +         P+ FCLN        +I  +  +       M T  
Sbjct: 1837 GQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNY-------EINVQCCECVTQPTTMTTTT 1889

Query: 1836 TRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTV 1895
            T N    +    T+    TPT  P+  QTP     P  +  +++P   P+   TQ PTT 
Sbjct: 1890 TENPTPPTTTPITTTTTVTPTPTPTGTQTPT--TTPITTTTTVTPT--PTPTGTQTPTTT 1945

Query: 1896 STGKPTSQVPAPPPPAQPPP 1915
                 T+  P P P     P
Sbjct: 1946 PITTTTTVTPTPTPTGTQTP 1965



 Score = 39.7 bits (91), Expect = 0.036
 Identities = 34/152 (22%), Positives = 54/152 (35%), Gaps = 22/152 (14%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+  +
Sbjct: 4135 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 4194

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPG-- 1946
            T PPT  ST        + PPP    P    +      E+          + +++PP   
Sbjct: 4195 TGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTES--------TTLLSTLPPAIE 4246

Query: 1947 RTGMGTPGSQMAPVSLN-----VPRPNQVSGP 1973
             T    P +  AP + +      P P+  + P
Sbjct: 4247 MTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSP 4278



 Score = 37.7 bits (86), Expect = 0.14
 Identities = 48/240 (20%), Positives = 75/240 (31%), Gaps = 35/240 (14%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 4020 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 4077

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRT 1948
            TQ PTT      T+  P P P     P                     +    ++ P  T
Sbjct: 4078 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-----------------ITTTTTVTPTPT 4120

Query: 1949 GMGTPGSQMAPVSLN---VPRPNQVSGPVMPSMPPGQWQQAPLPQQQP---MPGLPRPVI 2002
              GT      P++      P P   +G   P+  P        P   P         P+ 
Sbjct: 4121 PTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4179

Query: 2003 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSP--SSPQQQQQVLNILKSNPQLMA 2060
            +         P      PP   S + + +L  +   P  S+PQ  +   + L  +  L++
Sbjct: 4180 TTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLS 4239



 Score = 37.7 bits (86), Expect = 0.14
 Identities = 49/216 (22%), Positives = 67/216 (31%), Gaps = 42/216 (19%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 4112 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 4169

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQP--PPAAVEAARQIEREAQQQQHLYRVNINNSMPPG 1946
            TQ PTT      T+  P P P      PP     A   E             +  S PP 
Sbjct: 4170 TQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAE-------------LTTSNPP- 4215

Query: 1947 RTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQA 2006
                  P S     S +   P   S  ++ ++PP     +  P   P            A
Sbjct: 4216 ------PESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTP-----------TA 4258

Query: 2007 QAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSP 2042
                +G    S  P  + SP        T  S S+P
Sbjct: 4259 PTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAP 4294



 Score = 36.6 bits (83), Expect = 0.31
 Identities = 45/208 (21%), Positives = 65/208 (31%), Gaps = 35/208 (16%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 4089 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 4146

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRT 1948
            TQ PTT      T+  P P P     P                     +    ++ P  T
Sbjct: 4147 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTP-----------------ITTTTTVTPTPT 4189

Query: 1949 GMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPP--GQWQQAPLPQQQPMPGLPRPVISMQA 2006
              GT        S         S P   S  P   +   +PL +   +     P I M +
Sbjct: 4190 PTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 4249

Query: 2007 QAAVAGPRMP-------SVQPPRSISPS 2027
             A  + P  P       ++ PP S + S
Sbjct: 4250 TAPPSTPTAPTTTSGGHTLSPPPSTTTS 4277



 Score = 36.2 bits (82), Expect = 0.40
 Identities = 31/150 (20%), Positives = 43/150 (28%), Gaps = 13/150 (8%)

Query: 1886 VARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPP 1945
            +    PPTT  +  PTS    PP     PP                     +    + PP
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPP-----ITTTTTPPP 1450

Query: 1946 GRTGMGTPGSQMAPVSLNVPRP--NQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPV-- 2001
              T      +   P     P P     S P     PP      P P   P P    P+  
Sbjct: 1451 TTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP 1510

Query: 2002 ----ISMQAQAAVAGPRMPSVQPPRSISPS 2027
                 ++      + P   +  PP + +PS
Sbjct: 1511 PASTTTLPPTTTPSPPTTTTTTPPPTTTPS 1540



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 1950 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2007

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2008 TQTPTTTPITTTTTVTPTPTPTGTQTP 2034



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 1973 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2030

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2031 TQTPTTTPITTTTTVTPTPTPTGTQTP 2057



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 1996 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2053

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2054 TQTPTTTPITTTTTVTPTPTPTGTQTP 2080



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2019 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2076

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2077 TQTPTTTPITTTTTVTPTPTPTGTQTP 2103



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2042 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2099

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2100 TQTPTTTPITTTTTVTPTPTPTGTQTP 2126



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2065 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2122

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2123 TQTPTTTPITTTTTVTPTPTPTGTQTP 2149



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2088 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2145

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2146 TQTPTTTPITTTTTVTPTPTPTGTQTP 2172



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2111 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2168

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2169 TQTPTTTPITTTTTVTPTPTPTGTQTP 2195



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2134 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2191

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2192 TQTPTTTPITTTTTVTPTPTPTGTQTP 2218



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2157 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2214

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2215 TQTPTTTPITTTTTVTPTPTPTGTQTP 2241



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2180 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2237

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2238 TQTPTTTPITTTTTVTPTPTPTGTQTP 2264



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2203 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2260

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2261 TQTPTTTPITTTTTVTPTPTPTGTQTP 2287



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2226 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2283

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2284 TQTPTTTPITTTTTVTPTPTPTGTQTP 2310



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2249 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2306

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2307 TQTPTTTPITTTTTVTPTPTPTGTQTP 2333



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2272 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2329

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2330 TQTPTTTPITTTTTVTPTPTPTGTQTP 2356



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2295 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2352

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2353 TQTPTTTPITTTTTVTPTPTPTGTQTP 2379



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2318 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2375

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2376 TQTPTTTPITTTTTVTPTPTPTGTQTP 2402



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2341 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2398

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2399 TQTPTTTPITTTTTVTPTPTPTGTQTP 2425



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2364 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2421

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2422 TQTPTTTPITTTTTVTPTPTPTGTQTP 2448



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2387 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2444

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2445 TQTPTTTPITTTTTVTPTPTPTGTQTP 2471



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2410 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2467

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2468 TQTPTTTPITTTTTVTPTPTPTGTQTP 2494



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2433 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2490

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2491 TQTPTTTPITTTTTVTPTPTPTGTQTP 2517



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2456 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2513

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2514 TQTPTTTPITTTTTVTPTPTPTGTQTP 2540



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2479 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2536

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2537 TQTPTTTPITTTTTVTPTPTPTGTQTP 2563



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2502 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2559

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2560 TQTPTTTPITTTTTVTPTPTPTGTQTP 2586



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2525 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2582

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2583 TQTPTTTPITTTTTVTPTPTPTGTQTP 2609



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2548 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2605

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2606 TQTPTTTPITTTTTVTPTPTPTGTQTP 2632



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2571 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2628

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2629 TQTPTTTPITTTTTVTPTPTPTGTQTP 2655



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2594 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2651

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2652 TQTPTTTPITTTTTVTPTPTPTGTQTP 2678



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2617 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2674

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2675 TQTPTTTPITTTTTVTPTPTPTGTQTP 2701



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2640 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2697

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2698 TQTPTTTPITTTTTVTPTPTPTGTQTP 2724



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2663 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2720

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2721 TQTPTTTPITTTTTVTPTPTPTGTQTP 2747



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2686 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2743

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2744 TQTPTTTPITTTTTVTPTPTPTGTQTP 2770



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2709 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2766

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2767 TQTPTTTPITTTTTVTPTPTPTGTQTP 2793



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2732 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2789

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2790 TQTPTTTPITTTTTVTPTPTPTGTQTP 2816



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2755 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2812

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2813 TQTPTTTPITTTTTVTPTPTPTGTQTP 2839



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2778 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2835

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2836 TQTPTTTPITTTTTVTPTPTPTGTQTP 2862



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2801 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2858

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2859 TQTPTTTPITTTTTVTPTPTPTGTQTP 2885



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2824 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2881

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2882 TQTPTTTPITTTTTVTPTPTPTGTQTP 2908



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2847 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2904

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2905 TQTPTTTPITTTTTVTPTPTPTGTQTP 2931



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2870 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2927

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2928 TQTPTTTPITTTTTVTPTPTPTGTQTP 2954



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2893 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2950

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2951 TQTPTTTPITTTTTVTPTPTPTGTQTP 2977



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2916 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2973

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2974 TQTPTTTPITTTTTVTPTPTPTGTQTP 3000



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2939 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 2996

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 2997 TQTPTTTPITTTTTVTPTPTPTGTQTP 3023



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2962 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3019

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3020 TQTPTTTPITTTTTVTPTPTPTGTQTP 3046



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 2985 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3042

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3043 TQTPTTTPITTTTTVTPTPTPTGTQTP 3069



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3008 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3065

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3066 TQTPTTTPITTTTTVTPTPTPTGTQTP 3092



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3031 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3088

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3089 TQTPTTTPITTTTTVTPTPTPTGTQTP 3115



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3054 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3111

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3112 TQTPTTTPITTTTTVTPTPTPTGTQTP 3138



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3077 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3134

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3135 TQTPTTTPITTTTTVTPTPTPTGTQTP 3161



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3100 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3157

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3158 TQTPTTTPITTTTTVTPTPTPTGTQTP 3184



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3123 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3180

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3181 TQTPTTTPITTTTTVTPTPTPTGTQTP 3207



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3146 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3203

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3204 TQTPTTTPITTTTTVTPTPTPTGTQTP 3230



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3169 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3226

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3227 TQTPTTTPITTTTTVTPTPTPTGTQTP 3253



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3192 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3249

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3250 TQTPTTTPITTTTTVTPTPTPTGTQTP 3276



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3215 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3272

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3273 TQTPTTTPITTTTTVTPTPTPTGTQTP 3299



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3238 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3295

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3296 TQTPTTTPITTTTTVTPTPTPTGTQTP 3322



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3261 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3318

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3319 TQTPTTTPITTTTTVTPTPTPTGTQTP 3345



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3284 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3341

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3342 TQTPTTTPITTTTTVTPTPTPTGTQTP 3368



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3307 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3364

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3365 TQTPTTTPITTTTTVTPTPTPTGTQTP 3391



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3330 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3387

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3388 TQTPTTTPITTTTTVTPTPTPTGTQTP 3414



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3353 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3410

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3411 TQTPTTTPITTTTTVTPTPTPTGTQTP 3437



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3376 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3433

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3434 TQTPTTTPITTTTTVTPTPTPTGTQTP 3460



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3399 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3456

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3457 TQTPTTTPITTTTTVTPTPTPTGTQTP 3483



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3422 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3479

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3480 TQTPTTTPITTTTTVTPTPTPTGTQTP 3506



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3445 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3502

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3503 TQTPTTTPITTTTTVTPTPTPTGTQTP 3529



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3468 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3525

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3526 TQTPTTTPITTTTTVTPTPTPTGTQTP 3552



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3491 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3548

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3549 TQTPTTTPITTTTTVTPTPTPTGTQTP 3575



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3514 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3571

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3572 TQTPTTTPITTTTTVTPTPTPTGTQTP 3598



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3537 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3594

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3595 TQTPTTTPITTTTTVTPTPTPTGTQTP 3621



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3560 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3617

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3618 TQTPTTTPITTTTTVTPTPTPTGTQTP 3644



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3583 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3640

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3641 TQTPTTTPITTTTTVTPTPTPTGTQTP 3667



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3606 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3663

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3664 TQTPTTTPITTTTTVTPTPTPTGTQTP 3690



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3629 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3686

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3687 TQTPTTTPITTTTTVTPTPTPTGTQTP 3713



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3652 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3709

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3710 TQTPTTTPITTTTTVTPTPTPTGTQTP 3736



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3675 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3732

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3733 TQTPTTTPITTTTTVTPTPTPTGTQTP 3759



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3698 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3755

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3756 TQTPTTTPITTTTTVTPTPTPTGTQTP 3782



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3721 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3778

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3779 TQTPTTTPITTTTTVTPTPTPTGTQTP 3805



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3744 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3801

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3802 TQTPTTTPITTTTTVTPTPTPTGTQTP 3828



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3767 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3824

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3825 TQTPTTTPITTTTTVTPTPTPTGTQTP 3851



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3790 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3847

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3848 TQTPTTTPITTTTTVTPTPTPTGTQTP 3874



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3813 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3870

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3871 TQTPTTTPITTTTTVTPTPTPTGTQTP 3897



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3836 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3893

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3894 TQTPTTTPITTTTTVTPTPTPTGTQTP 3920



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3859 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3916

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3917 TQTPTTTPITTTTTVTPTPTPTGTQTP 3943



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3882 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3939

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3940 TQTPTTTPITTTTTVTPTPTPTGTQTP 3966



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3905 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3962

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3963 TQTPTTTPITTTTTVTPTPTPTGTQTP 3989



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3928 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 3985

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 3986 TQTPTTTPITTTTTVTPTPTPTGTQTP 4012



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3951 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 4008

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 4009 TQTPTTTPITTTTTVTPTPTPTGTQTP 4035



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 24/87 (27%), Positives = 32/87 (36%), Gaps = 9/87 (10%)

Query: 1836 TRNVPQQSLPSPTSAPPGTP-------TQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  V     P+ T  P  TP       T  P+   T  P   P  +  +++P   P+   
Sbjct: 3974 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--PTPTG 4031

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPP 1915
            TQ PTT      T+  P P P     P
Sbjct: 4032 TQTPTTTPITTTTTVTPTPTPTGTQTP 4058



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 36/156 (23%), Positives = 52/156 (33%), Gaps = 25/156 (16%)

Query: 1833 TMNTRNVPQQSLPSPTSAPPGT----PTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            T  T  +   +  +PT  P GT    PT   + P      + P P   +   +   S   
Sbjct: 4172 TPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPL 4231

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQP-PPAAVEAARQIEREAQQQQHLYRVNINNSMPPGR 1947
            T+  T +ST  P  ++ +  PP+ P  P        +                 + PPG 
Sbjct: 4232 TESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPS----------TTTSPPGT 4281

Query: 1948 TGMG-TPGSQMAPVSLNV---------PRPNQVSGP 1973
               G T GS  AP    V         P P  +S P
Sbjct: 4282 PTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTP 4317



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 23/56 (41%), Positives = 29/56 (51%), Gaps = 16/56 (28%)

Query: 1845 PSPTSAPPGTPTQ----------QPSTPQTPQPPA-QPQPSPVSMSPAGFPSVART 1889
            PS T++PPGTPT+           PST QT    A  P P+P+S      PS+ RT
Sbjct: 4272 PSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLST-----PSIIRT 4322



 Score = 32.7 bits (73), Expect = 4.4
 Identities = 29/123 (23%), Positives = 43/123 (34%), Gaps = 11/123 (8%)

Query: 1831 MATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQ 1890
            +A + T N P +S    TS    +P  + +T  +  PPA      + M+    PS     
Sbjct: 4206 IAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPA------IEMTSTAPPSTPTA- 4258

Query: 1891 PPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGM 1950
             PTT S G   S    PP     PP            +       +    ++  P  T +
Sbjct: 4259 -PTTTSGGHTLS---PPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPL 4314

Query: 1951 GTP 1953
             TP
Sbjct: 4315 STP 4317


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 91/343 (26%), Positives = 130/343 (37%), Gaps = 45/343 (13%)

Query: 757  PQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLH 816
            P    P+     S     PP +   S    P AA+P P     P A+ +P P    SP  
Sbjct: 1016 PAAAVPTPEEPTSPAAAVPPPEEPTS----PAAAVPTPEEPTSPAAA-VPTPEEPTSPAA 1070

Query: 817  --PTPP-PASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPT-PGSVPSAT 872
              PTP  P S AA +P+ +  T P    P P  PT P+  V      PTP  P S  +A 
Sbjct: 1071 AVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAV------PTPEEPASPAAAV 1124

Query: 873  QTQSTPTVQAAAQAQVTPQPQTPVQP-PSVATPQSSQQQ----PTPVHAQPPG----TPL 923
             T   P   AAA     P P+ P  P P+V TP+ S       PTP  +  P     TP 
Sbjct: 1125 PTPEEPASPAAA----VPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPA 1180

Query: 924  SQAA-----ASIDN------RVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDP 972
              A+     A+++        VPTP+++ +       P   VP  E      A  + P+ 
Sbjct: 1181 ESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEE 1240

Query: 973  GESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGT 1032
              S       + E     A+ +  E   +   S P   +   P   V   EE  S +   
Sbjct: 1241 PTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAV 1300

Query: 1033 ASQSTSPSQPRKKIFKPE--ELRQALMPTLEALYRQDPESLPF 1073
             +   + + P   +  PE   +  A +P +E +    P  +PF
Sbjct: 1301 PTPEVA-AIPAASVPTPEVPAIPAAAVPPMEEV---SPIGVPF 1339



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 82/273 (30%), Positives = 110/273 (40%), Gaps = 34/273 (12%)

Query: 806  PCPPVTQSPLHPTPP-PASTAAGMPSLQHTTPPGMTPPQPAAPTQPST-------PVSSS 857
            P  P + +   PTP  P S AA +P+ +  T P    P P  PT P+        P S +
Sbjct: 997  PEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPA 1056

Query: 858  GQTPTPT-PGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQP-PSVATPQSSQQQPTPVH 915
               PTP  P S  +A  T   PT  AAA     P P+ P  P  +V TP   ++  +P  
Sbjct: 1057 AAVPTPEEPTSPAAAVPTPEEPTSPAAA----VPTPEEPTSPAAAVPTP---EEPTSPAA 1109

Query: 916  AQP-PGTPLSQAAASIDNRVPT---PSSVASAETNSQQPGPDVPVLEMKTET-QAEDTEP 970
            A P P  P S AAA     VPT   P+S A+A    ++P    P +    E+  A    P
Sbjct: 1110 AVPTPEEPASPAAA-----VPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVP 1164

Query: 971  DPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSN 1030
             P ES     +  +    + AS       + E  S    V    P   V   EE  S + 
Sbjct: 1165 TPEESASP--AAAVPTPAESASFAAVVATLEEPTSPAASV--PTPAAMVATLEEFTSPA- 1219

Query: 1031 GTASQSTSPSQPRKKIFKPEELRQ--ALMPTLE 1061
             +   S  P+     +  PEE     A +PTLE
Sbjct: 1220 ASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLE 1252



 Score = 69.7 bits (169), Expect = 3e-11
 Identities = 88/325 (27%), Positives = 118/325 (36%), Gaps = 41/325 (12%)

Query: 655  PVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQ 714
            PV P A  V  P  P +  V   +VS      +P +   V  P+ P  P AA P      
Sbjct: 974  PVTP-ATTVHAPEEPDTAAV---RVSTPEEPASPAAA--VPTPEEPTSPAAAVPTPEEP- 1026

Query: 715  MNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQ 774
                 + P  A+ P   P  P           + A A    +P  + P+S  A      +
Sbjct: 1027 -----TSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAA----VPTPEEPTSPAAAVPTPEE 1077

Query: 775  PPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLH--PTPP-PASTAAGMPSL 831
            P +         P AA+P P     P A+ +P P    SP    PTP  PAS AA +P+ 
Sbjct: 1078 PTS---------PAAAVPTPEEPTSPAAA-VPTPEEPTSPAAAVPTPEEPASPAAAVPTP 1127

Query: 832  QHTTPPGM---TPPQPA--APTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQA 886
            +    P     TP +PA  AP  P+   S+S     PTP    S      TP   A+  A
Sbjct: 1128 EEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAA 1187

Query: 887  QVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETN 946
             V    +      SV TP +         +     P S+  AS+   V  P    S    
Sbjct: 1188 VVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTS---- 1243

Query: 947  SQQPGPDVPVLEMKTETQAEDTEPD 971
               P   VP LE  T + A    P+
Sbjct: 1244 ---PAAAVPTLEEPTSSAAAVLTPE 1265



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 57/238 (23%), Positives = 88/238 (36%), Gaps = 35/238 (14%)

Query: 1819 HRLQQAQLMRRRMATMNTRNVPQQSLPSP---TSAPPGTPT-QQPSTPQTPQPPAQPQPS 1874
            H  ++      R++T      P  ++P+P   TS     PT ++P++P    PP +   S
Sbjct: 982  HAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTS 1041

Query: 1875 PVSMSPAGF-PSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQH 1933
            P +  P    P+      PT      P + VP P  P   P AAV    +    A     
Sbjct: 1042 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS-PAAAVPTPEEPTSPA----- 1095

Query: 1934 LYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPV----MPSMPPGQWQQAPLP 1989
                            + TP    +P +  VP P + + P      P  P       P P
Sbjct: 1096 --------------AAVPTPEEPTSPAAA-VPTPEEPASPAAAVPTPEEPASPAAAVPTP 1140

Query: 1990 QQQ--PMPGLPRPVISMQAQAAVAGPR---MPSVQPPRSISPSALQDLLRTLKSPSSP 2042
            ++   P P +P P  S  A  AV  P     P+   P     ++   ++ TL+ P+SP
Sbjct: 1141 EEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSP 1198



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 79/351 (22%), Positives = 116/351 (33%), Gaps = 42/351 (11%)

Query: 750  PAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPP 809
            P   +++P  Q PS + A+      P  +  +       AALP+P    G   + +P P 
Sbjct: 822  PVLEEWIPVLQRPSRTAAV------PTVKDALD------AALPSPEE--GTSIAAVPAPE 867

Query: 810  VTQ--SPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVS--------SSGQ 859
             T   + L P P      A + SL+           P   T P+  VS        ++  
Sbjct: 868  GTAVVAALVPFPHEDILVASIVSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVS 927

Query: 860  TPTPTPGSVPSATQTQSTPTVQA--------AAQAQVTPQPQTPVQPPSVATPQSSQQQP 911
            +P  T  +V +A   +    V          A    +T +  TP  P + AT   + ++P
Sbjct: 928  SPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEP 987

Query: 912  --TPVHAQPPGTPLSQAAASIDNRVPT-PSSVASAETNSQQPGPDVPVLEMKTETQAEDT 968
                V    P  P S AAA      PT P++          P   VP  E  T   A   
Sbjct: 988  DTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVP 1047

Query: 969  EPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESS 1028
             P+   S         E     A+    E   +   + P   +   P   V   EE  S 
Sbjct: 1048 TPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSP 1107

Query: 1029 SNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDP 1079
            +    +    P+ P   +  PEE      P   A     PE   F  P  P
Sbjct: 1108 AAAVPTPE-EPASPAAAVPTPEE------PASPAAAVPTPEEPAFPAPAVP 1151



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 72/322 (22%), Positives = 116/322 (36%), Gaps = 62/322 (19%)

Query: 645  PALPAPGAQPPVIPQAQ---PVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGN----VQLP 697
            PA   P  + P  P A    P  P +   ++P      S       P    +    V  P
Sbjct: 1068 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTP 1127

Query: 698  QAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLP 757
            + P  P AA P        +  +VP    S S     P    + +       PA+S    
Sbjct: 1128 EEPASPAAAVPTPEEPAFPAP-AVPTPEESASAAVAVPTPEESASPAAAVPTPAES---- 1182

Query: 758  QNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGP------QASQLPCPP-- 809
                 +S  A+   + +P +         P A++P P  M+         A+ +P     
Sbjct: 1183 -----ASFAAVVATLEEPTS---------PAASVPTPAAMVATLEEFTSPAASVPTSEEP 1228

Query: 810  -----VTQSPLHPTPP---------PASTAAGMPSLQHTTPPGMTPPQPAAPTQPST--- 852
                    +P  PT P         P S+AA + + +  + P  + P P  P  P+    
Sbjct: 1229 ASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVS 1288

Query: 853  ----PVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQ-TPVQPPSVATPQSS 907
                P S +   PTP   ++P+A  +  TP V A   A V P  + +P+  P +    S+
Sbjct: 1289 NLEEPASPAAAVPTPEVAAIPAA--SVPTPEVPAIPAAAVPPMEEVSPIGVPFLGV--SA 1344

Query: 908  QQQPTPVHAQPPGTPLSQAAAS 929
                 P+  +  GTP+ + A+S
Sbjct: 1345 HTDSVPISEE--GTPVLEEASS 1364



 Score = 42.7 bits (99), Expect = 0.004
 Identities = 61/283 (21%), Positives = 92/283 (32%), Gaps = 61/283 (21%)

Query: 1847 PTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPA 1906
            PT   P +P     TP+ P  PA   P+P        P+      PT      P + VP 
Sbjct: 1086 PTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE------PASPAAAVPTPEEPASPAAAVPT 1139

Query: 1907 PPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPR 1966
            P  PA P PA                                 + TP  + A  ++ VP 
Sbjct: 1140 PEEPAFPAPA---------------------------------VPTP-EESASAAVAVPT 1165

Query: 1967 PNQVSGPVMPSMPPGQWQQ-----APLPQ-QQPMPGLPRPVISMQAQAAVAGPRMPSVQP 2020
            P + + P      P +        A L +   P   +P P   +   A +     P+   
Sbjct: 1166 PEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMV---ATLEEFTSPAASV 1222

Query: 2021 PRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQ 2080
            P S  P++L   +   + P+SP      L      P   AA +   T + +++     P 
Sbjct: 1223 PTSEEPASLAAAVSNPEEPTSPAAAVPTL----EEPTSSAAAV--LTPEELSSPAASVPT 1276

Query: 2081 PGLQSQPGM------QPQPGMHQQPSLQNLNAMQAGVPRPGVP 2117
            P   + P        +P       P+ +      A VP P VP
Sbjct: 1277 PEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVP 1319



 Score = 39.7 bits (91), Expect = 0.036
 Identities = 48/207 (23%), Positives = 71/207 (34%), Gaps = 31/207 (14%)

Query: 1840 PQQSLPSPTSAP---PGTPTQQPS--------TPQTPQPPAQPQPSPVSMSPAGFPSVAR 1888
            P  ++P+P       P  PT + S        TP+    PA   P+P     A F +V  
Sbjct: 1133 PAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAES--ASFAAVVA 1190

Query: 1889 T-QPPTTVSTGKPTSQV----------PAPPPPAQPPPAAVEAARQIEREAQQQQHLYRV 1937
            T + PT+ +   PT             PA   P    PA++ AA  +    +       V
Sbjct: 1191 TLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAA--VSNPEEPTSPAAAV 1248

Query: 1938 NINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMP----SMPPGQWQQAPLPQQQP 1993
                        + TP    +P + +VP P + + P         P       P P+   
Sbjct: 1249 PTLEEPTSSAAAVLTPEELSSPAA-SVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAA 1307

Query: 1994 MPGLPRPVISMQAQAAVAGPRMPSVQP 2020
            +P    P   + A  A A P M  V P
Sbjct: 1308 IPAASVPTPEVPAIPAAAVPPMEEVSP 1334



 Score = 35.0 bits (79), Expect = 0.89
 Identities = 24/81 (29%), Positives = 36/81 (44%), Gaps = 5/81 (6%)

Query: 1839 VPQQSLPSPTSAPPGTPTQQPS---TPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTV 1895
            VP    P+ ++A   TP +  S   +  TP+ PA P  +  ++     P+ A   P    
Sbjct: 1248 VPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAA 1307

Query: 1896 --STGKPTSQVPAPPPPAQPP 1914
              +   PT +VPA P  A PP
Sbjct: 1308 IPAASVPTPEVPAIPAAAVPP 1328



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 42/166 (25%), Positives = 61/166 (36%), Gaps = 17/166 (10%)

Query: 1889 TQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRT 1948
            T P  TVS  + T+ V A   P +  PA   A  Q    A          +  ++P    
Sbjct: 908  TVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEE 967

Query: 1949 GMGTPGSQMAPVSLNVPRPNQ-------VSGPVMPSMPPGQWQQAPLPQQ--QPMPGLPR 1999
              GTP   + P +  V  P +       VS P  P+ P       P P++   P   +P 
Sbjct: 968  D-GTPEGPVTPAT-TVHAPEEPDTAAVRVSTPEEPASPAA---AVPTPEEPTSPAAAVPT 1022

Query: 2000 PVISMQAQAAVAGPR---MPSVQPPRSISPSALQDLLRTLKSPSSP 2042
            P       AAV  P     P+   P    P++    + T + P+SP
Sbjct: 1023 PEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSP 1068



 Score = 32.0 bits (71), Expect = 7.5
 Identities = 32/105 (30%), Positives = 43/105 (40%), Gaps = 16/105 (15%)

Query: 1831 MATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPS---PVSMSPAGFPSVA 1887
            +AT+     P  S+P  TS  P +     S P+ P  PA   P+   P S + A      
Sbjct: 1209 VATLEEFTSPAASVP--TSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEE 1266

Query: 1888 RTQPPTTVST----GKPTSQV-----PAPPPPAQPPP--AAVEAA 1921
             + P  +V T      P + V     PA P  A P P  AA+ AA
Sbjct: 1267 LSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAA 1311


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 71/299 (23%), Positives = 104/299 (34%), Gaps = 16/299 (5%)

Query: 757  PQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLH 816
            P+   P++  +      +P   T  S    P    P       P   + P P  T+ P  
Sbjct: 229  PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 288

Query: 817  PTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQS 876
             T   A T    P+      P  T P+  APT P  P  ++ + P PT       T  + 
Sbjct: 289  TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 348

Query: 877  TPTV--QAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRV 934
             PT   + A      P P TP +P    T     ++P+P   + P  P +  +A    + 
Sbjct: 349  APTAPKKPAPTTPKEPAPTTPKEPAPTTT-----KEPSPTTPKEP-APTTTKSAPTTTKE 402

Query: 935  PTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQV 994
            P P++  SA T  ++P P       K        EP P   K +P     +E     +  
Sbjct: 403  PAPTTTKSAPTTPKEPSPTT----TKEPAPTTPKEPAPTTPK-KPAPTTPKE--PAPTTP 455

Query: 995  KEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKI-FKPEEL 1052
            KE      +K  P    E  P    E           T  +  +P+ P K     PEEL
Sbjct: 456  KEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL 514



 Score = 74.7 bits (182), Expect = 1e-12
 Identities = 90/415 (21%), Positives = 138/415 (33%), Gaps = 42/415 (10%)

Query: 699  APMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQ-SQFLP 757
            AP  P+  +P        +    P         P  P      T       P + +   P
Sbjct: 294  APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 353

Query: 758  QNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLG-PQASQLPCPPVTQSPLH 816
            +   P++    +    + PA T   +        P P      P  ++ P P  T+S   
Sbjct: 354  KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA-- 411

Query: 817  PTPP--PASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQT 874
            PT P  P+ T    P+      P  T P+  APT P  P  ++ + P PT    P+ T  
Sbjct: 412  PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP 471

Query: 875  QSTPTVQAAAQAQVTPQPQTPVQP----------PSVATPQ----SSQQQPTPVHAQPPG 920
            +          A  TP+  TP  P          P+  TP+    ++ ++PTP   + P 
Sbjct: 472  KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA 531

Query: 921  TPLSQAAASIDNRVPTPSSVAS-AETNSQQPGPDVPVLEMKTETQAED----TEPDPGES 975
                +AAA    + P P++    A T  ++P P  P     T  +        EP P   
Sbjct: 532  PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP 591

Query: 976  KGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVE-----VKEEEESSSN 1030
            K     E+        +  KE T     K  P       P    E      KE   ++  
Sbjct: 592  KKPAPKEL------APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 645

Query: 1031 GTASQS------TSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDP 1079
            GTA  +      T+P +P  K   P   +     T +      P+      P +P
Sbjct: 646  GTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP 700



 Score = 69.3 bits (168), Expect = 4e-11
 Identities = 63/300 (21%), Positives = 111/300 (37%), Gaps = 18/300 (6%)

Query: 1840 PQQSLPSPTSAPPGTPTQQ-PSTPQTPQPPAQPQPSPVS-MSPAGFPSVARTQPPTTVST 1897
            P++  P+ T  P  T T+  P+TP+ P P    +P+P +   PA  P+  +   PTT   
Sbjct: 275  PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA--PTTPKEPTPTTPKE 332

Query: 1898 GKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPG--- 1954
              PT++ PAP  P +P P A +       +              +  P  T    P    
Sbjct: 333  PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT 392

Query: 1955 SQMAPVSLNVPRPNQV-SGPVMPSMPPGQWQQAPLPQQQPMPGLPR-PVISMQAQAAVAG 2012
            ++ AP +   P P    S P  P  P      +P   ++P P  P+ P  +   + A   
Sbjct: 393  TKSAPTTTKEPAPTTTKSAPTTPKEP------SPTTTKEPAPTTPKEPAPTTPKKPAPTT 446

Query: 2013 PRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVA 2072
            P+ P+   P+  +P+  +    T     +P   ++      + P+ +     ++ A    
Sbjct: 447  PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET---APTTPKKLTPTTPEKLAPTTP 503

Query: 2073 NQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQA 2132
             +P       L      +P P   ++P+     A     P+   P   +      P+  A
Sbjct: 504  EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 563



 Score = 68.6 bits (166), Expect = 7e-11
 Identities = 95/472 (20%), Positives = 165/472 (34%), Gaps = 48/472 (10%)

Query: 626  ELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNS 685
            E+++ +++R  K+           P  +PPV+ +A      NG   +       +Q    
Sbjct: 65   EVKDNKKNRTKKK-----------PTPKPPVVDEAGSGLD-NGDFKVTTPDTSTTQ---- 108

Query: 686  FNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNM 745
             N +S         P+ PR + P N      +  +V       ++     N   +     
Sbjct: 109  HNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKE 168

Query: 746  MAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQL 805
               +  ++Q + +      +    V + +P   T  ++    G AL  P           
Sbjct: 169  KTTSAKETQSIEKTSAKDLAPTSKV-LAKP---TPKAETTTKGPALTTPKE----PTPTT 220

Query: 806  PCPPVTQSPLHPTPPPASTAAGMPS--LQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTP 863
            P  P + +P  PTP    +A   P      TT    T P+  APT    P  ++ + P P
Sbjct: 221  PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 280

Query: 864  T------PGSVPSATQTQSTPTVQAAAQ-AQVTPQPQTPVQP--PSVATPQS---SQQQP 911
            T      P +  SA  T   P      + A  TP+   P  P  P+  TP+    + ++P
Sbjct: 281  TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 340

Query: 912  TPVHAQPPGTPLSQAAASIDNRVPTPSSVAS-AETNSQQPGPDVPVLEMKTETQAEDT-- 968
             P   + P     +  A    + P P++    A T +++P P  P     T T++  T  
Sbjct: 341  APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 400

Query: 969  -EPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEES 1027
             EP P  +K  P +          +  KE      ++  P    +  P    E       
Sbjct: 401  KEPAPTTTKSAPTTPKE----PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 456

Query: 1028 SSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDP 1079
                T ++  +P+ P++    P   ++    T + L    PE L    P  P
Sbjct: 457  EPAPTTTKKPAPTTPKEP--APTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 506



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 61/306 (19%), Positives = 110/306 (35%), Gaps = 23/306 (7%)

Query: 1833 TMNTRNVPQQSLPSPTSAP-PGTPTQQ-PSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQ 1890
            T +    P++  P+    P P TP +  P+TP+ P P    +P+P +  PA  P+  +  
Sbjct: 291  TKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA--PTTPKEP 348

Query: 1891 PPTTVSTGKPTS-QVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTG 1949
             PT      PT+ + PAP  P +P P   +       +                P   T 
Sbjct: 349  APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 408

Query: 1950 MGTPGS--QMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPR-PVISMQA 2006
               P +  + +P +   P P     P  P+ P    + AP   ++P P  P+ P  +   
Sbjct: 409  KSAPTTPKEPSPTTTKEPAPTTPKEPA-PTTPK---KPAPTTPKEPAPTTPKEPAPTTTK 464

Query: 2007 QAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQR 2066
            + A   P+ P+   P+  +P+  + L  T     +P   ++      + P+ +A    + 
Sbjct: 465  KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP---APTTPEELAPTTPEE 521

Query: 2067 TAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGL 2126
                   +P              +P P   ++P+           P+   P   +     
Sbjct: 522  PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPA--------PTTPKEPAPTTPKETAPT 573

Query: 2127 NPQGQA 2132
             P+G A
Sbjct: 574  TPKGTA 579



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 64/281 (22%), Positives = 101/281 (35%), Gaps = 51/281 (18%)

Query: 1836 TRNVPQQSLPS-PTSAPPGTPTQQ-PSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPT 1893
            T   P++  P+ P +A P TP +  P+TP+ P P    +P+P +           T P T
Sbjct: 523  TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK--------ETAPTT 574

Query: 1894 TVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTP 1953
               T   T + PAP  P +P P   E A    +E          +     P   T  GT 
Sbjct: 575  PKGTAPTTLKEPAPTTPKKPAPK--ELAPTTTKEP--------TSTTCDKPAPTTPKGT- 623

Query: 1954 GSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLP--------------- 1998
                AP +   P P     P  P+ P G    AP   ++P P  P               
Sbjct: 624  ----APTTPKEPAPTTPKEPA-PTTPKG---TAPTTLKEPAPTTPKKPAPKELAPTTTKG 675

Query: 1999 -------RPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNI 2051
                   +P  +   + A   P+ P+   P+  +P+  +    T    S+P   ++   I
Sbjct: 676  PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTI 735

Query: 2052 LKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQ 2092
             KS  +       + T K + N P     P  ++    +P+
Sbjct: 736  HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPE 776



 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 93/446 (20%), Positives = 151/446 (33%), Gaps = 51/446 (11%)

Query: 644  QPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGP 703
            +PA   P    P  P+      P  P   P      +         +      P  P  P
Sbjct: 505  KPAPTTPEELAPTTPEEPTPTTPEEPA--PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 562

Query: 704  RAASPMNHSVQMNSMGSVPGMAISPS----RMPQPPNMMGAHTN---NMMAQAPAQSQFL 756
               +P   +      G+ P     P+    + P P  +    T    +     PA +   
Sbjct: 563  APTTP-KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT-- 619

Query: 757  PQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLH 816
            P+   P++    +    + PA T       P    P  L    P   + P P      L 
Sbjct: 620  PKGTAPTTPKEPAPTTPKEPAPT------TPKGTAPTTLKEPAPTTPKKPAP----KELA 669

Query: 817  PTPP--PASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQT 874
            PT    P ST +  P+         T P+  APT P  P  ++ +TP PT   V      
Sbjct: 670  PTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV------ 723

Query: 875  QSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPV----HAQPPGTPLSQAAASI 930
             STPT         T +P T  + P  +TP+ S  +PTP       + PG P ++  A+ 
Sbjct: 724  -STPT--------TTKEPTTIHKSPDESTPELS-AEPTPKALENSPKEPGVPTTKTPAAT 773

Query: 931  DNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQG 990
               + T +   + E + +            T+  A  TE           +++     Q 
Sbjct: 774  KPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQD 833

Query: 991  ASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSS----NGTASQSTSPSQPRKKI 1046
             +  K  T +      P     KK     E+  + E ++      T S++T+P +P+K  
Sbjct: 834  TTPFK-ITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTP-KPQKPT 891

Query: 1047 FKPEELRQALMPTLEALYRQDPESLP 1072
              P++      P      R+ P++ P
Sbjct: 892  KAPKKPTSTKKPKTMPRVRK-PKTTP 916



 Score = 58.5 bits (140), Expect = 8e-08
 Identities = 62/278 (22%), Positives = 111/278 (39%), Gaps = 35/278 (12%)

Query: 1832 ATMNTRNVP---QQSLPSPTSAPPGTPTQ-QPSTPQTPQPPAQPQPSPVS-MSPAGFPSV 1886
            A   T++ P   ++  P+ T + P TP +  P+T + P P    +P+P +   PA  P+ 
Sbjct: 389  APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA--PTT 446

Query: 1887 ARTQPPTTVSTGKP-TSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMP- 1944
             +   PTT     P T++ PAP  P +P P   +     E      + L         P 
Sbjct: 447  PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK-----ETAPTTPKKLTPTTPEKLAPT 501

Query: 1945 -PGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPR-PVI 2002
             P +    TP  ++AP +   P P     P  P+ P      AP   ++P P  P+ P  
Sbjct: 502  TPEKPAPTTP-EELAPTTPEEPTPTTPEEPA-PTTPKA---AAPNTPKEPAPTTPKEPAP 556

Query: 2003 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF 2062
            +   + A   P+  +   P+  +P+ L++      +P++P+         K  P+ +A  
Sbjct: 557  TTPKEPAPTTPKETAPTTPKGTAPTTLKE-----PAPTTPK---------KPAPKELAPT 602

Query: 2063 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPS 2100
              +       ++P      G       +P P   ++P+
Sbjct: 603  TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA 640



 Score = 55.8 bits (133), Expect = 5e-07
 Identities = 59/262 (22%), Positives = 95/262 (36%), Gaps = 31/262 (11%)

Query: 1848 TSAPPGTPTQQPSTPQTPQPPAQP---QPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQV 1904
            T+  P   T +  TP TP+ PA     +P+P ++  A  P+  +   PTT  +   T + 
Sbjct: 204  TTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA--PTTPKEPAPTTTKSAPTTPKE 261

Query: 1905 PAPPPPAQPPPAA-VEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLN 1963
            PAP    +P P    E A    +E                P       T   + AP +  
Sbjct: 262  PAPTTTKEPAPTTPKEPAPTTTKE--------------PAPTTTKSAPTTPKEPAPTTPK 307

Query: 1964 VPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRS 2023
             P P     P  P+ P    +  P   ++P P    P  +   + A   P+ P+   P+ 
Sbjct: 308  KPAPTTPKEPA-PTTPK---EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE 363

Query: 2024 ISPSALQD-LLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPG 2082
             +P+  ++    T K PS    ++      KS P          T K     P  +P P 
Sbjct: 364  PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE-PAPTTTKSAPTTP-KEPSPT 421

Query: 2083 LQSQPG----MQPQPGMHQQPS 2100
               +P      +P P   ++P+
Sbjct: 422  TTKEPAPTTPKEPAPTTPKKPA 443



 Score = 55.1 bits (131), Expect = 8e-07
 Identities = 59/300 (19%), Positives = 104/300 (34%), Gaps = 34/300 (11%)

Query: 1840 PQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQP-QPSPVSMSPAGFPSVARTQPPTTVSTG 1898
            P++  P+    P  T  ++P+       P  P +P+P +   A  P+  +   PTT    
Sbjct: 213  PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA--PTTPKEPAPTTTKEP 270

Query: 1899 KPTS-QVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQM 1957
             PT+ + PAP    +P P   ++A    +E                 P +    TP  + 
Sbjct: 271  APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA------------PTTPKKPAPTTP-KEP 317

Query: 1958 APVSLNVPRPNQVSGPVMPSMPPGQW---QQAPLPQQQPMPGLPR-PVISMQAQAAVAGP 2013
            AP +   P P     P   +  P      + AP   ++P P  P+ P  +   + A    
Sbjct: 318  APTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 377

Query: 2014 RMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVAN 2073
            + PS   P+  +P+  +    T K P+    +       + +P          T K  A 
Sbjct: 378  KEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP---------TTTKEPAP 428

Query: 2074 QPGMQPQPGLQSQPG----MQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQ 2129
                +P P    +P      +P P   ++P+           P+   P   +      P+
Sbjct: 429  TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 488



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 27/97 (27%), Positives = 35/97 (36%), Gaps = 7/97 (7%)

Query: 1845 PSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVS-MSPAGFPSVARTQPPTTVSTGKPTSQ 1903
            P  T+ P    T   +T   PQ P +    P S   P   P V +  P TT +  K TS 
Sbjct: 867  PEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRK--PKTTPTPRKMTST 924

Query: 1904 VPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNIN 1940
            +    P   P     EA  Q      Q  +   V +N
Sbjct: 925  M----PELNPTSRIAEAMLQTTTRPNQTPNSKLVEVN 957


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 71/299 (23%), Positives = 104/299 (34%), Gaps = 16/299 (5%)

Query: 757  PQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLH 816
            P+   P++  +      +P   T  S    P    P       P   + P P  T+ P  
Sbjct: 270  PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 329

Query: 817  PTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQS 876
             T   A T    P+      P  T P+  APT P  P  ++ + P PT       T  + 
Sbjct: 330  TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 389

Query: 877  TPTV--QAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRV 934
             PT   + A      P P TP +P    T     ++P+P   + P  P +  +A    + 
Sbjct: 390  APTAPKKPAPTTPKEPAPTTPKEPAPTTT-----KEPSPTTPKEP-APTTTKSAPTTTKE 443

Query: 935  PTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQV 994
            P P++  SA T  ++P P       K        EP P   K +P     +E     +  
Sbjct: 444  PAPTTTKSAPTTPKEPSPTT----TKEPAPTTPKEPAPTTPK-KPAPTTPKE--PAPTTP 496

Query: 995  KEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKI-FKPEEL 1052
            KE      +K  P    E  P    E           T  +  +P+ P K     PEEL
Sbjct: 497  KEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL 555



 Score = 74.7 bits (182), Expect = 1e-12
 Identities = 90/415 (21%), Positives = 138/415 (33%), Gaps = 42/415 (10%)

Query: 699  APMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQ-SQFLP 757
            AP  P+  +P        +    P         P  P      T       P + +   P
Sbjct: 335  APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 394

Query: 758  QNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLG-PQASQLPCPPVTQSPLH 816
            +   P++    +    + PA T   +        P P      P  ++ P P  T+S   
Sbjct: 395  KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA-- 452

Query: 817  PTPP--PASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQT 874
            PT P  P+ T    P+      P  T P+  APT P  P  ++ + P PT    P+ T  
Sbjct: 453  PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP 512

Query: 875  QSTPTVQAAAQAQVTPQPQTPVQP----------PSVATPQ----SSQQQPTPVHAQPPG 920
            +          A  TP+  TP  P          P+  TP+    ++ ++PTP   + P 
Sbjct: 513  KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA 572

Query: 921  TPLSQAAASIDNRVPTPSSVAS-AETNSQQPGPDVPVLEMKTETQAED----TEPDPGES 975
                +AAA    + P P++    A T  ++P P  P     T  +        EP P   
Sbjct: 573  PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP 632

Query: 976  KGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVE-----VKEEEESSSN 1030
            K     E+        +  KE T     K  P       P    E      KE   ++  
Sbjct: 633  KKPAPKEL------APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 686

Query: 1031 GTASQS------TSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDP 1079
            GTA  +      T+P +P  K   P   +     T +      P+      P +P
Sbjct: 687  GTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP 741



 Score = 69.3 bits (168), Expect = 4e-11
 Identities = 63/300 (21%), Positives = 111/300 (37%), Gaps = 18/300 (6%)

Query: 1840 PQQSLPSPTSAPPGTPTQQ-PSTPQTPQPPAQPQPSPVS-MSPAGFPSVARTQPPTTVST 1897
            P++  P+ T  P  T T+  P+TP+ P P    +P+P +   PA  P+  +   PTT   
Sbjct: 316  PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA--PTTPKEPTPTTPKE 373

Query: 1898 GKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPG--- 1954
              PT++ PAP  P +P P A +       +              +  P  T    P    
Sbjct: 374  PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT 433

Query: 1955 SQMAPVSLNVPRPNQV-SGPVMPSMPPGQWQQAPLPQQQPMPGLPR-PVISMQAQAAVAG 2012
            ++ AP +   P P    S P  P  P      +P   ++P P  P+ P  +   + A   
Sbjct: 434  TKSAPTTTKEPAPTTTKSAPTTPKEP------SPTTTKEPAPTTPKEPAPTTPKKPAPTT 487

Query: 2013 PRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVA 2072
            P+ P+   P+  +P+  +    T     +P   ++      + P+ +     ++ A    
Sbjct: 488  PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET---APTTPKKLTPTTPEKLAPTTP 544

Query: 2073 NQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQA 2132
             +P       L      +P P   ++P+     A     P+   P   +      P+  A
Sbjct: 545  EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 604



 Score = 68.6 bits (166), Expect = 7e-11
 Identities = 95/472 (20%), Positives = 165/472 (34%), Gaps = 48/472 (10%)

Query: 626  ELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNS 685
            E+++ +++R  K+           P  +PPV+ +A      NG   +       +Q    
Sbjct: 106  EVKDNKKNRTKKK-----------PTPKPPVVDEAGSGLD-NGDFKVTTPDTSTTQ---- 149

Query: 686  FNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNM 745
             N +S         P+ PR + P N      +  +V       ++     N   +     
Sbjct: 150  HNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKE 209

Query: 746  MAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQL 805
               +  ++Q + +      +    V + +P   T  ++    G AL  P           
Sbjct: 210  KTTSAKETQSIEKTSAKDLAPTSKV-LAKP---TPKAETTTKGPALTTPKE----PTPTT 261

Query: 806  PCPPVTQSPLHPTPPPASTAAGMPS--LQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTP 863
            P  P + +P  PTP    +A   P      TT    T P+  APT    P  ++ + P P
Sbjct: 262  PKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAP 321

Query: 864  T------PGSVPSATQTQSTPTVQAAAQ-AQVTPQPQTPVQP--PSVATPQS---SQQQP 911
            T      P +  SA  T   P      + A  TP+   P  P  P+  TP+    + ++P
Sbjct: 322  TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEP 381

Query: 912  TPVHAQPPGTPLSQAAASIDNRVPTPSSVAS-AETNSQQPGPDVPVLEMKTETQAEDT-- 968
             P   + P     +  A    + P P++    A T +++P P  P     T T++  T  
Sbjct: 382  APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 441

Query: 969  -EPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEES 1027
             EP P  +K  P +          +  KE      ++  P    +  P    E       
Sbjct: 442  KEPAPTTTKSAPTTPKE----PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 497

Query: 1028 SSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDP 1079
                T ++  +P+ P++    P   ++    T + L    PE L    P  P
Sbjct: 498  EPAPTTTKKPAPTTPKEP--APTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 547



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 61/306 (19%), Positives = 110/306 (35%), Gaps = 23/306 (7%)

Query: 1833 TMNTRNVPQQSLPSPTSAP-PGTPTQQ-PSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQ 1890
            T +    P++  P+    P P TP +  P+TP+ P P    +P+P +  PA  P+  +  
Sbjct: 332  TKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA--PTTPKEP 389

Query: 1891 PPTTVSTGKPTS-QVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTG 1949
             PT      PT+ + PAP  P +P P   +       +                P   T 
Sbjct: 390  APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 449

Query: 1950 MGTPGS--QMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPR-PVISMQA 2006
               P +  + +P +   P P     P  P+ P    + AP   ++P P  P+ P  +   
Sbjct: 450  KSAPTTPKEPSPTTTKEPAPTTPKEPA-PTTPK---KPAPTTPKEPAPTTPKEPAPTTTK 505

Query: 2007 QAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQR 2066
            + A   P+ P+   P+  +P+  + L  T     +P   ++      + P+ +A    + 
Sbjct: 506  KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP---APTTPEELAPTTPEE 562

Query: 2067 TAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGL 2126
                   +P              +P P   ++P+           P+   P   +     
Sbjct: 563  PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPA--------PTTPKEPAPTTPKETAPT 614

Query: 2127 NPQGQA 2132
             P+G A
Sbjct: 615  TPKGTA 620



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 64/281 (22%), Positives = 101/281 (35%), Gaps = 51/281 (18%)

Query: 1836 TRNVPQQSLPS-PTSAPPGTPTQQ-PSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPT 1893
            T   P++  P+ P +A P TP +  P+TP+ P P    +P+P +           T P T
Sbjct: 564  TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK--------ETAPTT 615

Query: 1894 TVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTP 1953
               T   T + PAP  P +P P   E A    +E          +     P   T  GT 
Sbjct: 616  PKGTAPTTLKEPAPTTPKKPAPK--ELAPTTTKEP--------TSTTCDKPAPTTPKGT- 664

Query: 1954 GSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLP--------------- 1998
                AP +   P P     P  P+ P G    AP   ++P P  P               
Sbjct: 665  ----APTTPKEPAPTTPKEPA-PTTPKG---TAPTTLKEPAPTTPKKPAPKELAPTTTKG 716

Query: 1999 -------RPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNI 2051
                   +P  +   + A   P+ P+   P+  +P+  +    T    S+P   ++   I
Sbjct: 717  PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTI 776

Query: 2052 LKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQ 2092
             KS  +       + T K + N P     P  ++    +P+
Sbjct: 777  HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPE 817



 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 93/446 (20%), Positives = 151/446 (33%), Gaps = 51/446 (11%)

Query: 644  QPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGP 703
            +PA   P    P  P+      P  P   P      +         +      P  P  P
Sbjct: 546  KPAPTTPEELAPTTPEEPTPTTPEEPA--PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 603

Query: 704  RAASPMNHSVQMNSMGSVPGMAISPS----RMPQPPNMMGAHTN---NMMAQAPAQSQFL 756
               +P   +      G+ P     P+    + P P  +    T    +     PA +   
Sbjct: 604  APTTP-KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT-- 660

Query: 757  PQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLH 816
            P+   P++    +    + PA T       P    P  L    P   + P P      L 
Sbjct: 661  PKGTAPTTPKEPAPTTPKEPAPT------TPKGTAPTTLKEPAPTTPKKPAP----KELA 710

Query: 817  PTPP--PASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQT 874
            PT    P ST +  P+         T P+  APT P  P  ++ +TP PT   V      
Sbjct: 711  PTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV------ 764

Query: 875  QSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPV----HAQPPGTPLSQAAASI 930
             STPT         T +P T  + P  +TP+ S  +PTP       + PG P ++  A+ 
Sbjct: 765  -STPT--------TTKEPTTIHKSPDESTPELS-AEPTPKALENSPKEPGVPTTKTPAAT 814

Query: 931  DNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQG 990
               + T +   + E + +            T+  A  TE           +++     Q 
Sbjct: 815  KPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQD 874

Query: 991  ASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSS----NGTASQSTSPSQPRKKI 1046
             +  K  T +      P     KK     E+  + E ++      T S++T+P +P+K  
Sbjct: 875  TTPFK-ITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTP-KPQKPT 932

Query: 1047 FKPEELRQALMPTLEALYRQDPESLP 1072
              P++      P      R+ P++ P
Sbjct: 933  KAPKKPTSTKKPKTMPRVRK-PKTTP 957



 Score = 58.5 bits (140), Expect = 8e-08
 Identities = 62/278 (22%), Positives = 111/278 (39%), Gaps = 35/278 (12%)

Query: 1832 ATMNTRNVP---QQSLPSPTSAPPGTPTQ-QPSTPQTPQPPAQPQPSPVS-MSPAGFPSV 1886
            A   T++ P   ++  P+ T + P TP +  P+T + P P    +P+P +   PA  P+ 
Sbjct: 430  APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA--PTT 487

Query: 1887 ARTQPPTTVSTGKP-TSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMP- 1944
             +   PTT     P T++ PAP  P +P P   +     E      + L         P 
Sbjct: 488  PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK-----ETAPTTPKKLTPTTPEKLAPT 542

Query: 1945 -PGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPR-PVI 2002
             P +    TP  ++AP +   P P     P  P+ P      AP   ++P P  P+ P  
Sbjct: 543  TPEKPAPTTP-EELAPTTPEEPTPTTPEEPA-PTTPKA---AAPNTPKEPAPTTPKEPAP 597

Query: 2003 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF 2062
            +   + A   P+  +   P+  +P+ L++      +P++P+         K  P+ +A  
Sbjct: 598  TTPKEPAPTTPKETAPTTPKGTAPTTLKE-----PAPTTPK---------KPAPKELAPT 643

Query: 2063 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPS 2100
              +       ++P      G       +P P   ++P+
Sbjct: 644  TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA 681



 Score = 55.8 bits (133), Expect = 5e-07
 Identities = 59/262 (22%), Positives = 95/262 (36%), Gaps = 31/262 (11%)

Query: 1848 TSAPPGTPTQQPSTPQTPQPPAQP---QPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQV 1904
            T+  P   T +  TP TP+ PA     +P+P ++  A  P+  +   PTT  +   T + 
Sbjct: 245  TTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA--PTTPKEPAPTTTKSAPTTPKE 302

Query: 1905 PAPPPPAQPPPAA-VEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLN 1963
            PAP    +P P    E A    +E                P       T   + AP +  
Sbjct: 303  PAPTTTKEPAPTTPKEPAPTTTKE--------------PAPTTTKSAPTTPKEPAPTTPK 348

Query: 1964 VPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRS 2023
             P P     P  P+ P    +  P   ++P P    P  +   + A   P+ P+   P+ 
Sbjct: 349  KPAPTTPKEPA-PTTPK---EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE 404

Query: 2024 ISPSALQD-LLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPG 2082
             +P+  ++    T K PS    ++      KS P          T K     P  +P P 
Sbjct: 405  PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE-PAPTTTKSAPTTP-KEPSPT 462

Query: 2083 LQSQPG----MQPQPGMHQQPS 2100
               +P      +P P   ++P+
Sbjct: 463  TTKEPAPTTPKEPAPTTPKKPA 484



 Score = 55.1 bits (131), Expect = 8e-07
 Identities = 59/300 (19%), Positives = 104/300 (34%), Gaps = 34/300 (11%)

Query: 1840 PQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQP-QPSPVSMSPAGFPSVARTQPPTTVSTG 1898
            P++  P+    P  T  ++P+       P  P +P+P +   A  P+  +   PTT    
Sbjct: 254  PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA--PTTPKEPAPTTTKEP 311

Query: 1899 KPTS-QVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQM 1957
             PT+ + PAP    +P P   ++A    +E                 P +    TP  + 
Sbjct: 312  APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA------------PTTPKKPAPTTP-KEP 358

Query: 1958 APVSLNVPRPNQVSGPVMPSMPPGQW---QQAPLPQQQPMPGLPR-PVISMQAQAAVAGP 2013
            AP +   P P     P   +  P      + AP   ++P P  P+ P  +   + A    
Sbjct: 359  APTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 418

Query: 2014 RMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVAN 2073
            + PS   P+  +P+  +    T K P+    +       + +P          T K  A 
Sbjct: 419  KEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP---------TTTKEPAP 469

Query: 2074 QPGMQPQPGLQSQPG----MQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQ 2129
                +P P    +P      +P P   ++P+           P+   P   +      P+
Sbjct: 470  TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 529



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 27/97 (27%), Positives = 35/97 (36%), Gaps = 7/97 (7%)

Query: 1845 PSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVS-MSPAGFPSVARTQPPTTVSTGKPTSQ 1903
            P  T+ P    T   +T   PQ P +    P S   P   P V +  P TT +  K TS 
Sbjct: 908  PEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRK--PKTTPTPRKMTST 965

Query: 1904 VPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNIN 1940
            +    P   P     EA  Q      Q  +   V +N
Sbjct: 966  M----PELNPTSRIAEAMLQTTTRPNQTPNSKLVEVN 998


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 71/299 (23%), Positives = 104/299 (34%), Gaps = 16/299 (5%)

Query: 757  PQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLH 816
            P+   P++  +      +P   T  S    P    P       P   + P P  T+ P  
Sbjct: 322  PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 381

Query: 817  PTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQS 876
             T   A T    P+      P  T P+  APT P  P  ++ + P PT       T  + 
Sbjct: 382  TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 441

Query: 877  TPTV--QAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRV 934
             PT   + A      P P TP +P    T     ++P+P   + P  P +  +A    + 
Sbjct: 442  APTAPKKPAPTTPKEPAPTTPKEPAPTTT-----KEPSPTTPKEP-APTTTKSAPTTTKE 495

Query: 935  PTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQV 994
            P P++  SA T  ++P P       K        EP P   K +P     +E     +  
Sbjct: 496  PAPTTTKSAPTTPKEPSPTT----TKEPAPTTPKEPAPTTPK-KPAPTTPKE--PAPTTP 548

Query: 995  KEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKI-FKPEEL 1052
            KE      +K  P    E  P    E           T  +  +P+ P K     PEEL
Sbjct: 549  KEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL 607



 Score = 74.7 bits (182), Expect = 1e-12
 Identities = 90/415 (21%), Positives = 138/415 (33%), Gaps = 42/415 (10%)

Query: 699  APMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQ-SQFLP 757
            AP  P+  +P        +    P         P  P      T       P + +   P
Sbjct: 387  APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 446

Query: 758  QNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLG-PQASQLPCPPVTQSPLH 816
            +   P++    +    + PA T   +        P P      P  ++ P P  T+S   
Sbjct: 447  KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA-- 504

Query: 817  PTPP--PASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQT 874
            PT P  P+ T    P+      P  T P+  APT P  P  ++ + P PT    P+ T  
Sbjct: 505  PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP 564

Query: 875  QSTPTVQAAAQAQVTPQPQTPVQP----------PSVATPQ----SSQQQPTPVHAQPPG 920
            +          A  TP+  TP  P          P+  TP+    ++ ++PTP   + P 
Sbjct: 565  KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA 624

Query: 921  TPLSQAAASIDNRVPTPSSVAS-AETNSQQPGPDVPVLEMKTETQAED----TEPDPGES 975
                +AAA    + P P++    A T  ++P P  P     T  +        EP P   
Sbjct: 625  PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP 684

Query: 976  KGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVE-----VKEEEESSSN 1030
            K     E+        +  KE T     K  P       P    E      KE   ++  
Sbjct: 685  KKPAPKEL------APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 738

Query: 1031 GTASQS------TSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDP 1079
            GTA  +      T+P +P  K   P   +     T +      P+      P +P
Sbjct: 739  GTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP 793



 Score = 70.5 bits (171), Expect = 2e-11
 Identities = 99/493 (20%), Positives = 174/493 (35%), Gaps = 42/493 (8%)

Query: 605  SANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVR 664
            S++S      + + K     +EL++K + + +K+     +P       +PPV+ +A    
Sbjct: 131  SSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPT-----PKPPVVDEAGSGL 185

Query: 665  PPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGM 724
              NG   +       +Q     N +S         P+ PR + P N      +  +V   
Sbjct: 186  D-NGDFKVTTPDTSTTQ----HNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKE 240

Query: 725  AISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQG 784
                ++     N   +        +  ++Q + +      +    V + +P   T  ++ 
Sbjct: 241  TTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV-LAKP---TPKAET 296

Query: 785  QVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPS--LQHTTPPGMTPP 842
               G AL  P           P  P + +P  PTP    +A   P      TT    T P
Sbjct: 297  TTKGPALTTPKE----PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTP 352

Query: 843  QPAAPTQPSTPVSSSGQTPTPT------PGSVPSATQTQSTPTVQAAAQ-AQVTPQPQTP 895
            +  APT    P  ++ + P PT      P +  SA  T   P      + A  TP+   P
Sbjct: 353  KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP 412

Query: 896  VQP--PSVATPQS---SQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVAS-AETNSQQ 949
              P  P+  TP+    + ++P P   + P     +  A    + P P++    A T +++
Sbjct: 413  TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 472

Query: 950  PGPDVPVLEMKTETQAEDT---EPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSE 1006
            P P  P     T T++  T   EP P  +K  P +          +  KE      ++  
Sbjct: 473  PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE----PSPTTTKEPAPTTPKEPA 528

Query: 1007 PMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQ 1066
            P    +  P    E           T ++  +P+ P++    P   ++    T + L   
Sbjct: 529  PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP--APTTPKETAPTTPKKLTPT 586

Query: 1067 DPESLPFRQPVDP 1079
             PE L    P  P
Sbjct: 587  TPEKLAPTTPEKP 599



 Score = 69.3 bits (168), Expect = 4e-11
 Identities = 63/300 (21%), Positives = 111/300 (37%), Gaps = 18/300 (6%)

Query: 1840 PQQSLPSPTSAPPGTPTQQ-PSTPQTPQPPAQPQPSPVS-MSPAGFPSVARTQPPTTVST 1897
            P++  P+ T  P  T T+  P+TP+ P P    +P+P +   PA  P+  +   PTT   
Sbjct: 368  PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA--PTTPKEPTPTTPKE 425

Query: 1898 GKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPG--- 1954
              PT++ PAP  P +P P A +       +              +  P  T    P    
Sbjct: 426  PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT 485

Query: 1955 SQMAPVSLNVPRPNQV-SGPVMPSMPPGQWQQAPLPQQQPMPGLPR-PVISMQAQAAVAG 2012
            ++ AP +   P P    S P  P  P      +P   ++P P  P+ P  +   + A   
Sbjct: 486  TKSAPTTTKEPAPTTTKSAPTTPKEP------SPTTTKEPAPTTPKEPAPTTPKKPAPTT 539

Query: 2013 PRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVA 2072
            P+ P+   P+  +P+  +    T     +P   ++      + P+ +     ++ A    
Sbjct: 540  PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET---APTTPKKLTPTTPEKLAPTTP 596

Query: 2073 NQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQA 2132
             +P       L      +P P   ++P+     A     P+   P   +      P+  A
Sbjct: 597  EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 656



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 61/306 (19%), Positives = 110/306 (35%), Gaps = 23/306 (7%)

Query: 1833 TMNTRNVPQQSLPSPTSAP-PGTPTQQ-PSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQ 1890
            T +    P++  P+    P P TP +  P+TP+ P P    +P+P +  PA  P+  +  
Sbjct: 384  TKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA--PTTPKEP 441

Query: 1891 PPTTVSTGKPTS-QVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTG 1949
             PT      PT+ + PAP  P +P P   +       +                P   T 
Sbjct: 442  APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 501

Query: 1950 MGTPGS--QMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPR-PVISMQA 2006
               P +  + +P +   P P     P  P+ P    + AP   ++P P  P+ P  +   
Sbjct: 502  KSAPTTPKEPSPTTTKEPAPTTPKEPA-PTTPK---KPAPTTPKEPAPTTPKEPAPTTTK 557

Query: 2007 QAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQR 2066
            + A   P+ P+   P+  +P+  + L  T     +P   ++      + P+ +A    + 
Sbjct: 558  KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP---APTTPEELAPTTPEE 614

Query: 2067 TAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGL 2126
                   +P              +P P   ++P+           P+   P   +     
Sbjct: 615  PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPA--------PTTPKEPAPTTPKETAPT 666

Query: 2127 NPQGQA 2132
             P+G A
Sbjct: 667  TPKGTA 672



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 64/281 (22%), Positives = 101/281 (35%), Gaps = 51/281 (18%)

Query: 1836 TRNVPQQSLPS-PTSAPPGTPTQQ-PSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPT 1893
            T   P++  P+ P +A P TP +  P+TP+ P P    +P+P +           T P T
Sbjct: 616  TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK--------ETAPTT 667

Query: 1894 TVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTP 1953
               T   T + PAP  P +P P   E A    +E          +     P   T  GT 
Sbjct: 668  PKGTAPTTLKEPAPTTPKKPAPK--ELAPTTTKEP--------TSTTCDKPAPTTPKGT- 716

Query: 1954 GSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLP--------------- 1998
                AP +   P P     P  P+ P G    AP   ++P P  P               
Sbjct: 717  ----APTTPKEPAPTTPKEPA-PTTPKG---TAPTTLKEPAPTTPKKPAPKELAPTTTKG 768

Query: 1999 -------RPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNI 2051
                   +P  +   + A   P+ P+   P+  +P+  +    T    S+P   ++   I
Sbjct: 769  PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTI 828

Query: 2052 LKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQ 2092
             KS  +       + T K + N P     P  ++    +P+
Sbjct: 829  HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPE 869



 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 93/446 (20%), Positives = 151/446 (33%), Gaps = 51/446 (11%)

Query: 644  QPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGP 703
            +PA   P    P  P+      P  P   P      +         +      P  P  P
Sbjct: 598  KPAPTTPEELAPTTPEEPTPTTPEEPA--PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 655

Query: 704  RAASPMNHSVQMNSMGSVPGMAISPS----RMPQPPNMMGAHTN---NMMAQAPAQSQFL 756
               +P   +      G+ P     P+    + P P  +    T    +     PA +   
Sbjct: 656  APTTP-KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT-- 712

Query: 757  PQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLH 816
            P+   P++    +    + PA T       P    P  L    P   + P P      L 
Sbjct: 713  PKGTAPTTPKEPAPTTPKEPAPT------TPKGTAPTTLKEPAPTTPKKPAP----KELA 762

Query: 817  PTPP--PASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQT 874
            PT    P ST +  P+         T P+  APT P  P  ++ +TP PT   V      
Sbjct: 763  PTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV------ 816

Query: 875  QSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPV----HAQPPGTPLSQAAASI 930
             STPT         T +P T  + P  +TP+ S  +PTP       + PG P ++  A+ 
Sbjct: 817  -STPT--------TTKEPTTIHKSPDESTPELS-AEPTPKALENSPKEPGVPTTKTPAAT 866

Query: 931  DNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQG 990
               + T +   + E + +            T+  A  TE           +++     Q 
Sbjct: 867  KPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQD 926

Query: 991  ASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSS----NGTASQSTSPSQPRKKI 1046
             +  K  T +      P     KK     E+  + E ++      T S++T+P +P+K  
Sbjct: 927  TTPFK-ITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTP-KPQKPT 984

Query: 1047 FKPEELRQALMPTLEALYRQDPESLP 1072
              P++      P      R+ P++ P
Sbjct: 985  KAPKKPTSTKKPKTMPRVRK-PKTTP 1009



 Score = 58.5 bits (140), Expect = 8e-08
 Identities = 62/278 (22%), Positives = 111/278 (39%), Gaps = 35/278 (12%)

Query: 1832 ATMNTRNVP---QQSLPSPTSAPPGTPTQ-QPSTPQTPQPPAQPQPSPVS-MSPAGFPSV 1886
            A   T++ P   ++  P+ T + P TP +  P+T + P P    +P+P +   PA  P+ 
Sbjct: 482  APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA--PTT 539

Query: 1887 ARTQPPTTVSTGKP-TSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMP- 1944
             +   PTT     P T++ PAP  P +P P   +     E      + L         P 
Sbjct: 540  PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK-----ETAPTTPKKLTPTTPEKLAPT 594

Query: 1945 -PGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPR-PVI 2002
             P +    TP  ++AP +   P P     P  P+ P      AP   ++P P  P+ P  
Sbjct: 595  TPEKPAPTTP-EELAPTTPEEPTPTTPEEPA-PTTPKA---AAPNTPKEPAPTTPKEPAP 649

Query: 2003 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF 2062
            +   + A   P+  +   P+  +P+ L++      +P++P+         K  P+ +A  
Sbjct: 650  TTPKEPAPTTPKETAPTTPKGTAPTTLKE-----PAPTTPK---------KPAPKELAPT 695

Query: 2063 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPS 2100
              +       ++P      G       +P P   ++P+
Sbjct: 696  TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA 733



 Score = 55.8 bits (133), Expect = 5e-07
 Identities = 59/262 (22%), Positives = 95/262 (36%), Gaps = 31/262 (11%)

Query: 1848 TSAPPGTPTQQPSTPQTPQPPAQP---QPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQV 1904
            T+  P   T +  TP TP+ PA     +P+P ++  A  P+  +   PTT  +   T + 
Sbjct: 297  TTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA--PTTPKEPAPTTTKSAPTTPKE 354

Query: 1905 PAPPPPAQPPPAA-VEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLN 1963
            PAP    +P P    E A    +E                P       T   + AP +  
Sbjct: 355  PAPTTTKEPAPTTPKEPAPTTTKE--------------PAPTTTKSAPTTPKEPAPTTPK 400

Query: 1964 VPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRS 2023
             P P     P  P+ P    +  P   ++P P    P  +   + A   P+ P+   P+ 
Sbjct: 401  KPAPTTPKEPA-PTTPK---EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE 456

Query: 2024 ISPSALQD-LLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPG 2082
             +P+  ++    T K PS    ++      KS P          T K     P  +P P 
Sbjct: 457  PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE-PAPTTTKSAPTTP-KEPSPT 514

Query: 2083 LQSQPG----MQPQPGMHQQPS 2100
               +P      +P P   ++P+
Sbjct: 515  TTKEPAPTTPKEPAPTTPKKPA 536



 Score = 55.1 bits (131), Expect = 8e-07
 Identities = 59/300 (19%), Positives = 104/300 (34%), Gaps = 34/300 (11%)

Query: 1840 PQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQP-QPSPVSMSPAGFPSVARTQPPTTVSTG 1898
            P++  P+    P  T  ++P+       P  P +P+P +   A  P+  +   PTT    
Sbjct: 306  PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA--PTTPKEPAPTTTKEP 363

Query: 1899 KPTS-QVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQM 1957
             PT+ + PAP    +P P   ++A    +E                 P +    TP  + 
Sbjct: 364  APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA------------PTTPKKPAPTTP-KEP 410

Query: 1958 APVSLNVPRPNQVSGPVMPSMPPGQW---QQAPLPQQQPMPGLPR-PVISMQAQAAVAGP 2013
            AP +   P P     P   +  P      + AP   ++P P  P+ P  +   + A    
Sbjct: 411  APTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 470

Query: 2014 RMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVAN 2073
            + PS   P+  +P+  +    T K P+    +       + +P          T K  A 
Sbjct: 471  KEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP---------TTTKEPAP 521

Query: 2074 QPGMQPQPGLQSQPG----MQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQ 2129
                +P P    +P      +P P   ++P+           P+   P   +      P+
Sbjct: 522  TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 581



 Score = 38.1 bits (87), Expect = 0.11
 Identities = 56/254 (22%), Positives = 103/254 (40%), Gaps = 39/254 (15%)

Query: 816  HPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPST-------------PVSSSGQTPT 862
            +PT PP+S  A  PS    T    T   P  P +  T              VS + ++ +
Sbjct: 68   NPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSS 127

Query: 863  PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP 922
             +  S  S+T  +   +  +AA  ++  Q +  V+         ++++PTP   +PP   
Sbjct: 128  SSSSSSSSSTIRKIKSSKNSAANREL--QKKLKVKDNK---KNRTKKKPTP---KPP--V 177

Query: 923  LSQAAASIDN---RVPTPSSVASAETNSQQPGPDV---------PVLEMKTETQAEDTEP 970
            + +A + +DN   +V TP + ++ + N     P +         P L   ++T  E +  
Sbjct: 178  VDEAGSGLDNGDFKVTTPDT-STTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLT 236

Query: 971  DPGESKGEPRSEMMEEDLQGASQVKEETDIAE--QKSEPMEVDEKKPEVKVEVKEEEESS 1028
               E+  E + E    + Q ++  KE+T  A+  Q  E     +  P  KV  K   ++ 
Sbjct: 237  VNKETTVETK-ETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAE 295

Query: 1029 SNGTASQSTSPSQP 1042
            +       T+P +P
Sbjct: 296  TTTKGPALTTPKEP 309



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 27/97 (27%), Positives = 35/97 (36%), Gaps = 7/97 (7%)

Query: 1845 PSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVS-MSPAGFPSVARTQPPTTVSTGKPTSQ 1903
            P  T+ P    T   +T   PQ P +    P S   P   P V +  P TT +  K TS 
Sbjct: 960  PEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRK--PKTTPTPRKMTST 1017

Query: 1904 VPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNIN 1940
            +    P   P     EA  Q      Q  +   V +N
Sbjct: 1018 M----PELNPTSRIAEAMLQTTTRPNQTPNSKLVEVN 1050


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 71/299 (23%), Positives = 104/299 (34%), Gaps = 16/299 (5%)

Query: 757  PQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLH 816
            P+   P++  +      +P   T  S    P    P       P   + P P  T+ P  
Sbjct: 363  PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAP 422

Query: 817  PTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQS 876
             T   A T    P+      P  T P+  APT P  P  ++ + P PT       T  + 
Sbjct: 423  TTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEP 482

Query: 877  TPTV--QAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRV 934
             PT   + A      P P TP +P    T     ++P+P   + P  P +  +A    + 
Sbjct: 483  APTAPKKPAPTTPKEPAPTTPKEPAPTTT-----KEPSPTTPKEP-APTTTKSAPTTTKE 536

Query: 935  PTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQV 994
            P P++  SA T  ++P P       K        EP P   K +P     +E     +  
Sbjct: 537  PAPTTTKSAPTTPKEPSPTT----TKEPAPTTPKEPAPTTPK-KPAPTTPKE--PAPTTP 589

Query: 995  KEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKI-FKPEEL 1052
            KE      +K  P    E  P    E           T  +  +P+ P K     PEEL
Sbjct: 590  KEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL 648



 Score = 74.7 bits (182), Expect = 1e-12
 Identities = 90/415 (21%), Positives = 138/415 (33%), Gaps = 42/415 (10%)

Query: 699  APMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQ-SQFLP 757
            AP  P+  +P        +    P         P  P      T       P + +   P
Sbjct: 428  APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 487

Query: 758  QNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLG-PQASQLPCPPVTQSPLH 816
            +   P++    +    + PA T   +        P P      P  ++ P P  T+S   
Sbjct: 488  KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSA-- 545

Query: 817  PTPP--PASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQT 874
            PT P  P+ T    P+      P  T P+  APT P  P  ++ + P PT    P+ T  
Sbjct: 546  PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP 605

Query: 875  QSTPTVQAAAQAQVTPQPQTPVQP----------PSVATPQ----SSQQQPTPVHAQPPG 920
            +          A  TP+  TP  P          P+  TP+    ++ ++PTP   + P 
Sbjct: 606  KEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA 665

Query: 921  TPLSQAAASIDNRVPTPSSVAS-AETNSQQPGPDVPVLEMKTETQAED----TEPDPGES 975
                +AAA    + P P++    A T  ++P P  P     T  +        EP P   
Sbjct: 666  PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTP 725

Query: 976  KGEPRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVE-----VKEEEESSSN 1030
            K     E+        +  KE T     K  P       P    E      KE   ++  
Sbjct: 726  KKPAPKEL------APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 779

Query: 1031 GTASQS------TSPSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDP 1079
            GTA  +      T+P +P  K   P   +     T +      P+      P +P
Sbjct: 780  GTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP 834



 Score = 70.5 bits (171), Expect = 2e-11
 Identities = 99/493 (20%), Positives = 174/493 (35%), Gaps = 42/493 (8%)

Query: 605  SANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVR 664
            S++S      + + K     +EL++K + + +K+     +P       +PPV+ +A    
Sbjct: 172  SSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPT-----PKPPVVDEAGSGL 226

Query: 665  PPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGM 724
              NG   +       +Q     N +S         P+ PR + P N      +  +V   
Sbjct: 227  D-NGDFKVTTPDTSTTQ----HNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKE 281

Query: 725  AISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQG 784
                ++     N   +        +  ++Q + +      +    V + +P   T  ++ 
Sbjct: 282  TTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV-LAKP---TPKAET 337

Query: 785  QVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPS--LQHTTPPGMTPP 842
               G AL  P           P  P + +P  PTP    +A   P      TT    T P
Sbjct: 338  TTKGPALTTPKE----PTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTP 393

Query: 843  QPAAPTQPSTPVSSSGQTPTPT------PGSVPSATQTQSTPTVQAAAQ-AQVTPQPQTP 895
            +  APT    P  ++ + P PT      P +  SA  T   P      + A  TP+   P
Sbjct: 394  KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP 453

Query: 896  VQP--PSVATPQS---SQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVAS-AETNSQQ 949
              P  P+  TP+    + ++P P   + P     +  A    + P P++    A T +++
Sbjct: 454  TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKE 513

Query: 950  PGPDVPVLEMKTETQAEDT---EPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSE 1006
            P P  P     T T++  T   EP P  +K  P +          +  KE      ++  
Sbjct: 514  PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE----PSPTTTKEPAPTTPKEPA 569

Query: 1007 PMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTLEALYRQ 1066
            P    +  P    E           T ++  +P+ P++    P   ++    T + L   
Sbjct: 570  PTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP--APTTPKETAPTTPKKLTPT 627

Query: 1067 DPESLPFRQPVDP 1079
             PE L    P  P
Sbjct: 628  TPEKLAPTTPEKP 640



 Score = 69.3 bits (168), Expect = 4e-11
 Identities = 63/300 (21%), Positives = 111/300 (37%), Gaps = 18/300 (6%)

Query: 1840 PQQSLPSPTSAPPGTPTQQ-PSTPQTPQPPAQPQPSPVS-MSPAGFPSVARTQPPTTVST 1897
            P++  P+ T  P  T T+  P+TP+ P P    +P+P +   PA  P+  +   PTT   
Sbjct: 409  PKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA--PTTPKEPTPTTPKE 466

Query: 1898 GKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPG--- 1954
              PT++ PAP  P +P P A +       +              +  P  T    P    
Sbjct: 467  PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTT 526

Query: 1955 SQMAPVSLNVPRPNQV-SGPVMPSMPPGQWQQAPLPQQQPMPGLPR-PVISMQAQAAVAG 2012
            ++ AP +   P P    S P  P  P      +P   ++P P  P+ P  +   + A   
Sbjct: 527  TKSAPTTTKEPAPTTTKSAPTTPKEP------SPTTTKEPAPTTPKEPAPTTPKKPAPTT 580

Query: 2013 PRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVA 2072
            P+ P+   P+  +P+  +    T     +P   ++      + P+ +     ++ A    
Sbjct: 581  PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET---APTTPKKLTPTTPEKLAPTTP 637

Query: 2073 NQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQA 2132
             +P       L      +P P   ++P+     A     P+   P   +      P+  A
Sbjct: 638  EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPA 697



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 61/306 (19%), Positives = 110/306 (35%), Gaps = 23/306 (7%)

Query: 1833 TMNTRNVPQQSLPSPTSAP-PGTPTQQ-PSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQ 1890
            T +    P++  P+    P P TP +  P+TP+ P P    +P+P +  PA  P+  +  
Sbjct: 425  TKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA--PTTPKEP 482

Query: 1891 PPTTVSTGKPTS-QVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTG 1949
             PT      PT+ + PAP  P +P P   +       +                P   T 
Sbjct: 483  APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTT 542

Query: 1950 MGTPGS--QMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPR-PVISMQA 2006
               P +  + +P +   P P     P  P+ P    + AP   ++P P  P+ P  +   
Sbjct: 543  KSAPTTPKEPSPTTTKEPAPTTPKEPA-PTTPK---KPAPTTPKEPAPTTPKEPAPTTTK 598

Query: 2007 QAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQR 2066
            + A   P+ P+   P+  +P+  + L  T     +P   ++      + P+ +A    + 
Sbjct: 599  KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP---APTTPEELAPTTPEE 655

Query: 2067 TAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGL 2126
                   +P              +P P   ++P+           P+   P   +     
Sbjct: 656  PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPA--------PTTPKEPAPTTPKETAPT 707

Query: 2127 NPQGQA 2132
             P+G A
Sbjct: 708  TPKGTA 713



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 64/281 (22%), Positives = 101/281 (35%), Gaps = 51/281 (18%)

Query: 1836 TRNVPQQSLPS-PTSAPPGTPTQQ-PSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPT 1893
            T   P++  P+ P +A P TP +  P+TP+ P P    +P+P +           T P T
Sbjct: 657  TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPK--------ETAPTT 708

Query: 1894 TVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTP 1953
               T   T + PAP  P +P P   E A    +E          +     P   T  GT 
Sbjct: 709  PKGTAPTTLKEPAPTTPKKPAPK--ELAPTTTKEP--------TSTTCDKPAPTTPKGT- 757

Query: 1954 GSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLP--------------- 1998
                AP +   P P     P  P+ P G    AP   ++P P  P               
Sbjct: 758  ----APTTPKEPAPTTPKEPA-PTTPKG---TAPTTLKEPAPTTPKKPAPKELAPTTTKG 809

Query: 1999 -------RPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNI 2051
                   +P  +   + A   P+ P+   P+  +P+  +    T    S+P   ++   I
Sbjct: 810  PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTI 869

Query: 2052 LKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQ 2092
             KS  +       + T K + N P     P  ++    +P+
Sbjct: 870  HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPE 910



 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 93/446 (20%), Positives = 151/446 (33%), Gaps = 51/446 (11%)

Query: 644  QPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGP 703
            +PA   P    P  P+      P  P   P      +         +      P  P  P
Sbjct: 639  KPAPTTPEELAPTTPEEPTPTTPEEPA--PTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 696

Query: 704  RAASPMNHSVQMNSMGSVPGMAISPS----RMPQPPNMMGAHTN---NMMAQAPAQSQFL 756
               +P   +      G+ P     P+    + P P  +    T    +     PA +   
Sbjct: 697  APTTP-KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT-- 753

Query: 757  PQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLH 816
            P+   P++    +    + PA T       P    P  L    P   + P P      L 
Sbjct: 754  PKGTAPTTPKEPAPTTPKEPAPT------TPKGTAPTTLKEPAPTTPKKPAP----KELA 803

Query: 817  PTPP--PASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQT 874
            PT    P ST +  P+         T P+  APT P  P  ++ +TP PT   V      
Sbjct: 804  PTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEV------ 857

Query: 875  QSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPV----HAQPPGTPLSQAAASI 930
             STPT         T +P T  + P  +TP+ S  +PTP       + PG P ++  A+ 
Sbjct: 858  -STPT--------TTKEPTTIHKSPDESTPELS-AEPTPKALENSPKEPGVPTTKTPAAT 907

Query: 931  DNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQG 990
               + T +   + E + +            T+  A  TE           +++     Q 
Sbjct: 908  KPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQD 967

Query: 991  ASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSS----NGTASQSTSPSQPRKKI 1046
             +  K  T +      P     KK     E+  + E ++      T S++T+P +P+K  
Sbjct: 968  TTPFK-ITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTP-KPQKPT 1025

Query: 1047 FKPEELRQALMPTLEALYRQDPESLP 1072
              P++      P      R+ P++ P
Sbjct: 1026 KAPKKPTSTKKPKTMPRVRK-PKTTP 1050



 Score = 58.5 bits (140), Expect = 8e-08
 Identities = 62/278 (22%), Positives = 111/278 (39%), Gaps = 35/278 (12%)

Query: 1832 ATMNTRNVP---QQSLPSPTSAPPGTPTQ-QPSTPQTPQPPAQPQPSPVS-MSPAGFPSV 1886
            A   T++ P   ++  P+ T + P TP +  P+T + P P    +P+P +   PA  P+ 
Sbjct: 523  APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA--PTT 580

Query: 1887 ARTQPPTTVSTGKP-TSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMP- 1944
             +   PTT     P T++ PAP  P +P P   +     E      + L         P 
Sbjct: 581  PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPK-----ETAPTTPKKLTPTTPEKLAPT 635

Query: 1945 -PGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPR-PVI 2002
             P +    TP  ++AP +   P P     P  P+ P      AP   ++P P  P+ P  
Sbjct: 636  TPEKPAPTTP-EELAPTTPEEPTPTTPEEPA-PTTPKA---AAPNTPKEPAPTTPKEPAP 690

Query: 2003 SMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAF 2062
            +   + A   P+  +   P+  +P+ L++      +P++P+         K  P+ +A  
Sbjct: 691  TTPKEPAPTTPKETAPTTPKGTAPTTLKE-----PAPTTPK---------KPAPKELAPT 736

Query: 2063 IKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPS 2100
              +       ++P      G       +P P   ++P+
Sbjct: 737  TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA 774



 Score = 55.8 bits (133), Expect = 5e-07
 Identities = 59/262 (22%), Positives = 95/262 (36%), Gaps = 31/262 (11%)

Query: 1848 TSAPPGTPTQQPSTPQTPQPPAQP---QPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQV 1904
            T+  P   T +  TP TP+ PA     +P+P ++  A  P+  +   PTT  +   T + 
Sbjct: 338  TTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA--PTTPKEPAPTTTKSAPTTPKE 395

Query: 1905 PAPPPPAQPPPAA-VEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLN 1963
            PAP    +P P    E A    +E                P       T   + AP +  
Sbjct: 396  PAPTTTKEPAPTTPKEPAPTTTKE--------------PAPTTTKSAPTTPKEPAPTTPK 441

Query: 1964 VPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRS 2023
             P P     P  P+ P    +  P   ++P P    P  +   + A   P+ P+   P+ 
Sbjct: 442  KPAPTTPKEPA-PTTPK---EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE 497

Query: 2024 ISPSALQD-LLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPG 2082
             +P+  ++    T K PS    ++      KS P          T K     P  +P P 
Sbjct: 498  PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE-PAPTTTKSAPTTP-KEPSPT 555

Query: 2083 LQSQPG----MQPQPGMHQQPS 2100
               +P      +P P   ++P+
Sbjct: 556  TTKEPAPTTPKEPAPTTPKKPA 577



 Score = 55.1 bits (131), Expect = 8e-07
 Identities = 59/300 (19%), Positives = 104/300 (34%), Gaps = 34/300 (11%)

Query: 1840 PQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQP-QPSPVSMSPAGFPSVARTQPPTTVSTG 1898
            P++  P+    P  T  ++P+       P  P +P+P +   A  P+  +   PTT    
Sbjct: 347  PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA--PTTPKEPAPTTTKEP 404

Query: 1899 KPTS-QVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQM 1957
             PT+ + PAP    +P P   ++A    +E                 P +    TP  + 
Sbjct: 405  APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA------------PTTPKKPAPTTP-KEP 451

Query: 1958 APVSLNVPRPNQVSGPVMPSMPPGQW---QQAPLPQQQPMPGLPR-PVISMQAQAAVAGP 2013
            AP +   P P     P   +  P      + AP   ++P P  P+ P  +   + A    
Sbjct: 452  APTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 511

Query: 2014 RMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVAN 2073
            + PS   P+  +P+  +    T K P+    +       + +P          T K  A 
Sbjct: 512  KEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSP---------TTTKEPAP 562

Query: 2074 QPGMQPQPGLQSQPG----MQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQ 2129
                +P P    +P      +P P   ++P+           P+   P   +      P+
Sbjct: 563  TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK 622



 Score = 38.1 bits (87), Expect = 0.11
 Identities = 56/254 (22%), Positives = 103/254 (40%), Gaps = 39/254 (15%)

Query: 816  HPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPST-------------PVSSSGQTPT 862
            +PT PP+S  A  PS    T    T   P  P +  T              VS + ++ +
Sbjct: 109  NPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSS 168

Query: 863  PTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP 922
             +  S  S+T  +   +  +AA  ++  Q +  V+         ++++PTP   +PP   
Sbjct: 169  SSSSSSSSSTIRKIKSSKNSAANREL--QKKLKVKDNK---KNRTKKKPTP---KPP--V 218

Query: 923  LSQAAASIDN---RVPTPSSVASAETNSQQPGPDV---------PVLEMKTETQAEDTEP 970
            + +A + +DN   +V TP + ++ + N     P +         P L   ++T  E +  
Sbjct: 219  VDEAGSGLDNGDFKVTTPDT-STTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLT 277

Query: 971  DPGESKGEPRSEMMEEDLQGASQVKEETDIAE--QKSEPMEVDEKKPEVKVEVKEEEESS 1028
               E+  E + E    + Q ++  KE+T  A+  Q  E     +  P  KV  K   ++ 
Sbjct: 278  VNKETTVETK-ETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAE 336

Query: 1029 SNGTASQSTSPSQP 1042
            +       T+P +P
Sbjct: 337  TTTKGPALTTPKEP 350



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 27/97 (27%), Positives = 35/97 (36%), Gaps = 7/97 (7%)

Query: 1845 PSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVS-MSPAGFPSVARTQPPTTVSTGKPTSQ 1903
            P  T+ P    T   +T   PQ P +    P S   P   P V +  P TT +  K TS 
Sbjct: 1001 PEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRK--PKTTPTPRKMTST 1058

Query: 1904 VPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNIN 1940
            +    P   P     EA  Q      Q  +   V +N
Sbjct: 1059 M----PELNPTSRIAEAMLQTTTRPNQTPNSKLVEVN 1091


>gi|56549696 E1A binding protein p400 [Homo sapiens]
          Length = 3122

 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 123/478 (25%), Positives = 168/478 (35%), Gaps = 142/478 (29%)

Query: 1907 PPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPR 1966
            P PP Q      E   + ++    QQ   +  +  + PP       P  Q  P  L  P+
Sbjct: 2471 PLPPIQVASLRAERIAKEKKALADQQKAQQPAV--AQPPPPQPQPPPPPQQPPPPL--PQ 2526

Query: 1967 PNQVSGPVMPSMPPG-QWQQAPLPQQQPMP----GLPRPVISMQAQAAVAGPRMPSVQPP 2021
            P Q +G   P+ PP  Q Q  P PQ QP P       +P I+    AAV    + +    
Sbjct: 2527 P-QAAGSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPAITTGGSAAVLAGTIKT---- 2581

Query: 2022 RSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQP 2081
             S++ +++         P+       ++N +   P      I +R A  VA  PG    P
Sbjct: 2582 -SVTGTSM---------PTGAVSGNVIVNTIAGVPAATFQSINKRLASPVA--PGALTTP 2629

Query: 2082 GLQSQPGMQPQPGMHQQP-------------------SLQNLNAMQA----GVPRPGVPP 2118
            G     G  P   +H QP                   + Q + A+ +     V    + P
Sbjct: 2630 G-----GSAPAQVVHTQPPPRAVGSPATATPDLVSMATTQGVRAVTSVTASAVVTTNLTP 2684

Query: 2119 QQQAMGGLNPQ-GQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQ 2177
             Q     L PQ  QA  +  PG     A            QLL+QQQQQQQQQQQQQQQQ
Sbjct: 2685 VQTPARSLVPQVSQATGVQLPGKTITPAHF----------QLLRQQQQQQQQQQQQQQQQ 2734

Query: 2178 QGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMG 2237
            Q               QQ Q         QQQQ+ QQ                       
Sbjct: 2735 Q---------------QQQQ---------QQQQQQQQ----------------------- 2747

Query: 2238 QPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQI 2297
                    T    Q    +I  Q Q   QI + G+  P    +H++  Q Q   +P Q  
Sbjct: 2748 --------TTTTSQVQVPQIQGQAQSPAQIKAVGKLTP----EHLIKMQKQKLQMPPQ-- 2793

Query: 2298 ATSLSNQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQ---TGSPHPGLAVT 2352
                      P P   P+ QS PP  +   ++Q    P   SPQ     +P PG  +T
Sbjct: 2794 ----------PPP---PQAQSAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLT 2838



 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 154/617 (24%), Positives = 199/617 (32%), Gaps = 117/617 (18%)

Query: 1803 PFCLNIKHK--LRQQQIQHR-----LQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTP 1855
            PF  N KH   L +  I +      +Q A L   R+A        QQ    P  A P  P
Sbjct: 2450 PFQKNPKHASVLAESGINYDKPLPPIQVASLRAERIAKEKKALADQQKAQQPAVAQPPPP 2509

Query: 1856 TQQPSTPQTPQPPAQPQPSPV-SMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPP 1914
              QP  P    PP  PQP    S  PAG P+V   QP       +P  Q    P P Q P
Sbjct: 2510 QPQPPPPPQQPPPPLPQPQAAGSQPPAGPPAV---QP-------QPQPQPQTQPQPVQAP 2559

Query: 1915 PAAVEAARQIEREAQQQQHLYRVNINNSMPPG--------RTGMGTPGSQMAPVSLNVPR 1966
              A  A       A     +       SMP G         T  G P +    ++     
Sbjct: 2560 AKAQPAITTGGSAAVLAGTIKTSVTGTSMPTGAVSGNVIVNTIAGVPAATFQSIN----- 2614

Query: 1967 PNQVSGPVMPS--MPPGQWQQAPLPQQQPMP---GLP----------------RPVISMQ 2005
              +++ PV P     PG    A +   QP P   G P                R V S+ 
Sbjct: 2615 -KRLASPVAPGALTTPGGSAPAQVVHTQPPPRAVGSPATATPDLVSMATTQGVRAVTSVT 2673

Query: 2006 AQAAVAGPRMPSVQPPRSISPSALQ----------------DLLRTLKSPSSPQQQQQVL 2049
            A A V     P   P RS+ P   Q                 LLR  +     QQQQQ  
Sbjct: 2674 ASAVVTTNLTPVQTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQQQ 2733

Query: 2050 NILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQ-------------------PGMQ 2090
               +   Q      +Q T       P +Q Q    +Q                     M 
Sbjct: 2734 QQQQQQQQQQQQ--QQTTTTSQVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMP 2791

Query: 2091 PQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNPNMASM-NP 2149
            PQP   Q  S       Q  V +   PPQQQ     +PQ   +    PG      ++ N 
Sbjct: 2792 PQPPPPQAQSAPPQPTAQVQV-QTSQPPQQQ-----SPQLTTVTAPRPGALLTGTTVANL 2845

Query: 2150 QYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAG------MAGGMAGHGQFQQPQGPGGYP 2203
            Q   + R    Q Q Q Q Q Q  Q  Q   A        A  ++  G    P    G  
Sbjct: 2846 QVARLTRVPTSQLQAQGQMQTQAPQPAQVALAKPPVVSVPAAVVSSPGVTTLPMNVAGIS 2905

Query: 2204 PAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQM 2263
             A+ Q Q+        G ++      M QL ++ Q  +        Q A     +QQ+  
Sbjct: 2906 VAIGQPQK------AAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQAAQGPAAVQQKIT 2959

Query: 2264 KQQIGSPG-------QPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRP 2316
             QQI +PG          P    Q + +   QA  L G Q   +     + P  VQ   P
Sbjct: 2960 AQQITTPGAQQKVAYAAQPALKTQFLTTPISQAQKLAGAQQVQTQIQVAKLPQVVQQQTP 3019

Query: 2317 -QSQPPHSSPSPRIQPQ 2332
              S    +S S +  PQ
Sbjct: 3020 VASIQQVASASQQASPQ 3036



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 73/326 (22%), Positives = 120/326 (36%), Gaps = 42/326 (12%)

Query: 783  QGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPP 842
            + Q P  A P P     P   Q P PP+ Q     + PPA   A  P  Q   P   T P
Sbjct: 2497 KAQQPAVAQPPPPQPQPPPPPQQPPPPLPQPQAAGSQPPAGPPAVQPQPQ---PQPQTQP 2553

Query: 843  QPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPT--------------VQAAAQAQV 888
            QP      + P  ++G +     G++ ++    S PT              V AA    +
Sbjct: 2554 QPVQAPAKAQPAITTGGSAAVLAGTIKTSVTGTSMPTGAVSGNVIVNTIAGVPAATFQSI 2613

Query: 889  TPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQ 948
              +  +PV P ++ TP  S      VH QPP   +   A +      TP  V+ A T   
Sbjct: 2614 NKRLASPVAPGALTTPGGSAPAQV-VHTQPPPRAVGSPATA------TPDLVSMATTQGV 2666

Query: 949  QPGPDVPVLEMKT------ETQAEDTEPDPGESKGE--PRSEMMEEDLQGASQVKEETDI 1000
            +    V    + T      +T A    P   ++ G   P   +     Q   Q       
Sbjct: 2667 RAVTSVTASAVVTTNLTPVQTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQ------- 2719

Query: 1001 AEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTSPSQPRKKIFKPEELRQALMPTL 1060
             +Q+ +  +  +++ + + + +++++     T SQ   P Q + +   P +++     T 
Sbjct: 2720 -QQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQVQVP-QIQGQAQSPAQIKAVGKLTP 2777

Query: 1061 EALYRQDPESLPF-RQPVDPQLLGIP 1085
            E L +   + L    QP  PQ    P
Sbjct: 2778 EHLIKMQKQKLQMPPQPPPPQAQSAP 2803



 Score = 63.2 bits (152), Expect = 3e-09
 Identities = 134/553 (24%), Positives = 198/553 (35%), Gaps = 73/553 (13%)

Query: 399 QAGKACQAILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQP 458
           Q  +  Q  L  P + I  T+      Q +  S    + + P S   A  A GL  +  P
Sbjct: 200 QIAQGAQVQLQHPGTPI--TVRERRPSQPHTQSGGTIHHLGPQSPAAAGGA-GLQPLASP 256

Query: 459 Q----TQLQPQVP----GQQPAQPQTHQQMRTLNPLG---NNPMNIP-AGGIT----TDQ 502
                  L PQ+     GQ   Q Q  Q      PLG      + +P AGG      T  
Sbjct: 257 SHITTANLPPQISSIIQGQLVQQQQVLQGPPLPRPLGFERTPGVLLPGAGGAAGFGMTSP 316

Query: 503 QPPNLISESALPTSLGATNPLMNDGSNSGNIGT------LSTIPTAAPPSSTGVRK---G 553
            PP   S +A+P  L +  PL    ++ GN G       L  IP A+P  +  +RK    
Sbjct: 317 PPPTSPSRTAVPPGLSSL-PL----TSVGNTGMKKVPKKLEEIPPASPEMAQ-MRKQCLD 370

Query: 554 WHEHVTQDLRSHLVHKLVQAIF------PTPDPAALKDRRMENLVAYAKKVEGDMYESAN 607
           +H    Q L+      L++  F         D  A K +    L AY ++ + D+ E   
Sbjct: 371 YHYQEMQALKEVFKEYLIELFFLQHFQGNMMDFLAFKKKHYAPLQAYLRQNDLDIEEEEE 430

Query: 608 SRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPN 667
             +E                EEK      +Q + G+  A      +  +  + Q +    
Sbjct: 431 EEEEE---------------EEKSEVINDEQALAGSLVAGAGSTVETDLFKRQQAMPSTG 475

Query: 668 GPLSLPVNRMQVS-QGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAI 726
                   R++V  QG+   +P +   V L Q     +   P        +         
Sbjct: 476 MAEQSKRPRLEVGHQGVVFQHPGADAGVPLQQLMPTAQGGMPPTPQAAQLAGQRQSQQQY 535

Query: 727 SPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPP----AQTGVS 782
            PS  P   N    HT   + Q P +   LP    P+++ + ++   Q P    AQT   
Sbjct: 536 DPSTGPPVQNAASLHTP--LPQLPGR---LPPAGVPTAALSSALQFAQQPQVVEAQT--- 587

Query: 783 QGQVPGAALPNPLNMLGPQASQLPCPPV--TQSPLH-PTPPPASTAAG-MPSLQHTTPPG 838
           Q Q+P       + +  P +SQLP PP    Q  LH PTP      A  + SL       
Sbjct: 588 QLQIPVKTQQPNVPIPAPPSSQLPIPPSQPAQLALHVPTPGKVQVQASQLSSLPQMVAST 647

Query: 839 MTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQP 898
             P  PA P     P SS+     P  GS P  +  +S+P  + ++       P T   P
Sbjct: 648 RLPVDPAPPCPRPLPTSSTSSL-APVSGSGPGPSPARSSPVNRPSSATNKALSPVTSRTP 706

Query: 899 PSVATPQSSQQQP 911
             VA+  +  Q P
Sbjct: 707 GVVASAPTKPQSP 719



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 81/355 (22%), Positives = 121/355 (34%), Gaps = 52/355 (14%)

Query: 646  ALPAPGAQPPVIPQAQPVRPPNGPLSLPVNR------MQVSQGMNSFNPMSLGNVQLPQA 699
            AL  PG   P   Q    +PP   +  P         M  +QG+ +   ++   V     
Sbjct: 2625 ALTTPGGSAPA--QVVHTQPPPRAVGSPATATPDLVSMATTQGVRAVTSVTASAVVTTNL 2682

Query: 700  PMGPRAASPMNHSVQMNSMGSVPGMAISPSR---MPQPPNMMGAHTNNMMAQAPAQSQFL 756
                  A  +   V   +   +PG  I+P+    + Q              Q   Q Q  
Sbjct: 2683 TPVQTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQQQQQQQQQQQQ 2742

Query: 757  PQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLH 816
             Q Q  +++  + V   Q  AQ   S  Q+       P +++  Q  +L  PP       
Sbjct: 2743 QQQQQTTTTSQVQVPQIQGQAQ---SPAQIKAVGKLTPEHLIKMQKQKLQMPP------Q 2793

Query: 817  PTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTP------TPTPGSVPS 870
            P PP A +A               PPQP A  Q  T      Q+P       P PG++ +
Sbjct: 2794 PPPPQAQSA---------------PPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGALLT 2838

Query: 871  ATQTQS--------TPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTP 922
             T   +         PT Q  AQ Q+  Q   P Q      P  S   P  V + P  T 
Sbjct: 2839 GTTVANLQVARLTRVPTSQLQAQGQMQTQAPQPAQVALAKPPVVS--VPAAVVSSPGVTT 2896

Query: 923  LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKG 977
            L    A I   +  P   A+ +T   QP     +L++K +   +     P  ++G
Sbjct: 2897 LPMNVAGISVAIGQPQK-AAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQAAQG 2950



 Score = 55.1 bits (131), Expect = 8e-07
 Identities = 86/335 (25%), Positives = 124/335 (37%), Gaps = 60/335 (17%)

Query: 1823 QAQLMRRRMATMNTRNVPQQSLP-----------SPTSAPPGTPTQQ---------PSTP 1862
            +  L +R+ A  +T    Q   P               A  G P QQ         P TP
Sbjct: 461  ETDLFKRQQAMPSTGMAEQSKRPRLEVGHQGVVFQHPGADAGVPLQQLMPTAQGGMPPTP 520

Query: 1863 QTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAAR 1922
            Q  Q   Q Q S     P+  P V         S   P  Q+P   PPA  P AA+ +A 
Sbjct: 521  QAAQLAGQRQ-SQQQYDPSTGPPVQNA-----ASLHTPLPQLPGRLPPAGVPTAALSSAL 574

Query: 1923 QIEREAQ--QQQHLYRVNINNSMP------PGRTGMGTPGSQMAPVSLNVPRPN--QVSG 1972
            Q  ++ Q  + Q   ++ +    P      P  + +  P SQ A ++L+VP P   QV  
Sbjct: 575  QFAQQPQVVEAQTQLQIPVKTQQPNVPIPAPPSSQLPIPPSQPAQLALHVPTPGKVQVQA 634

Query: 1973 PVMPSMPPGQWQQAPLPQQQPMPGLPRPV----ISMQAQAAVAGP-----RMPSVQPPRS 2023
              + S+P  Q   +      P P  PRP+     S  A  + +GP     R   V  P S
Sbjct: 635  SQLSSLP--QMVASTRLPVDPAPPCPRPLPTSSTSSLAPVSGSGPGPSPARSSPVNRPSS 692

Query: 2024 ISPSALQDLLR-----TLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQ 2078
             +  AL  +          +P+ PQ   Q  N   S         +Q T +   +Q   +
Sbjct: 693  ATNKALSPVTSRTPGVVASAPTKPQSPAQ--NATSSQDSSQDTLTEQITLENQVHQRIAE 750

Query: 2079 -PQPGLQSQ---PGMQ--PQPGMHQQPSLQNLNAM 2107
              + GL SQ   P +Q  P+P  H    L+ +  M
Sbjct: 751  LRKAGLWSQRRLPKLQEAPRPKSHWDYLLEEMQWM 785



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 94/415 (22%), Positives = 136/415 (32%), Gaps = 93/415 (22%)

Query: 615  LLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPP-NGPLSLP 673
            L AE+I K +K L ++++++         QPA+    AQPP  PQ QP  PP   P  LP
Sbjct: 2480 LRAERIAKEKKALADQQKAQ---------QPAV----AQPPP-PQPQPPPPPQQPPPPLP 2525

Query: 674  VNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQ 733
                          P + G+    Q P GP A  P                   P   PQ
Sbjct: 2526 -------------QPQAAGS----QPPAGPPAVQPQPQP--------------QPQTQPQ 2554

Query: 734  PPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPN 793
            P             QAPA++Q  P      S+  ++  +      T +  G V G  + N
Sbjct: 2555 P------------VQAPAKAQ--PAITTGGSAAVLAGTIKTSVTGTSMPTGAVSGNVIVN 2600

Query: 794  PL----------------NMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPP 837
             +                + + P A   P        +H  PPP +  +   +       
Sbjct: 2601 TIAGVPAATFQSINKRLASPVAPGALTTPGGSAPAQVVHTQPPPRAVGSPATATPDLVSM 2660

Query: 838  GMTPPQPAAPTQPSTPVSSSGQTPTPTPG-----SVPSATQTQSTPTVQAAAQAQVTPQP 892
              T    A  +  ++ V ++  TP  TP       V  AT  Q        A  Q+  Q 
Sbjct: 2661 ATTQGVRAVTSVTASAVVTTNLTPVQTPARSLVPQVSQATGVQLPGKTITPAHFQLLRQQ 2720

Query: 893  QTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGP 952
            Q   Q       Q  QQQ      Q   T  SQ       +VP     A +    +  G 
Sbjct: 2721 QQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTSQV------QVPQIQGQAQSPAQIKAVGK 2774

Query: 953  DVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAEQKSEP 1007
              P   +K + Q     P P      P  +      Q  +QV+ +T    Q+  P
Sbjct: 2775 LTPEHLIKMQKQKLQMPPQP------PPPQAQSAPPQPTAQVQVQTSQPPQQQSP 2823



 Score = 52.4 bits (124), Expect = 5e-06
 Identities = 142/659 (21%), Positives = 216/659 (32%), Gaps = 135/659 (20%)

Query: 1810 HKLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPA 1869
            H    Q +QH+LQ++    R          P    P P+ A P  P+  PS PQ+P    
Sbjct: 3    HGTGPQNVQHQLQRS----RACPGSEGEEQPAHPNPPPSPAAPFAPSASPSAPQSPSYQI 58

Query: 1870 Q---------------------------------PQPSPVSMSPAGFPSVARTQ-----P 1891
            Q                                 P P P   SP GF   A+ +      
Sbjct: 59   QQLMNRSPATGQNVNITLQSVGPVVGGNQQITLAPLPLPSPTSP-GFQFSAQPRRFEHGS 117

Query: 1892 PTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMG 1951
            P+ +    P SQ      P QP P   +A + +   A        + + +S P G  G  
Sbjct: 118  PSYIQVTSPLSQQVQTQSPTQPSPGPGQALQNVRAGAPGP----GLGLCSSSPTG--GFV 171

Query: 1952 TPGSQMAPVSLNVPRPNQV---SGPVMPSMPPG-----QWQQAPLPQQQPMPGLPRPV-- 2001
                 +  +SL+           G  +  +  G     Q    P+  ++  P  P     
Sbjct: 172  DASVLVRQISLSPSSGGHFVFQDGSGLTQIAQGAQVQLQHPGTPITVRERRPSQPHTQSG 231

Query: 2002 -----ISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNP 2056
                 +  Q+ AA  G  +  +  P  I+ + L   + ++      QQQQ     +   P
Sbjct: 232  GTIHHLGPQSPAAAGGAGLQPLASPSHITTANLPPQISSIIQGQLVQQQQ-----VLQGP 286

Query: 2057 QLMAAFIKQRTAKYV------ANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAG 2110
             L      +RT   +      A   GM   P   S       PG+   P     N     
Sbjct: 287  PLPRPLGFERTPGVLLPGAGGAAGFGMTSPPPPTSPSRTAVPPGLSSLPLTSVGNTGMKK 346

Query: 2111 VPR--PGVPPQQQAMGGLNPQ--------GQALNIM-------------NPGHNPNMASM 2147
            VP+    +PP    M  +  Q         QAL  +               G+  +  + 
Sbjct: 347  VPKKLEEIPPASPEMAQMRKQCLDYHYQEMQALKEVFKEYLIELFFLQHFQGNMMDFLAF 406

Query: 2148 NPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGS------AGMAGGM-AGHGQ------FQ 2194
              ++   L+  L Q     ++++++++++++ S        +AG + AG G       F+
Sbjct: 407  KKKHYAPLQAYLRQNDLDIEEEEEEEEEEEEKSEVINDEQALAGSLVAGAGSTVETDLFK 466

Query: 2195 QPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGL--GADSTPNIQQA 2252
            + Q       A +Q +R +  +  QG       A  G   Q   P    G   TP   Q 
Sbjct: 467  RQQAMPSTGMA-EQSKRPRLEVGHQGVVFQHPGADAGVPLQQLMPTAQGGMPPTPQAAQL 525

Query: 2253 LQQRILQQQQMKQQIGSPGQ-------PNPMSPQQHMLSGQPQASHLPGQQIA-----TS 2300
              QR   QQQ     G P Q       P P  P +   +G P A+     Q A       
Sbjct: 526  AGQR-QSQQQYDPSTGPPVQNAASLHTPLPQLPGRLPPAGVPTAALSSALQFAQQPQVVE 584

Query: 2301 LSNQVRSPAPVQSPR-PQSQPPHSS-PSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSI 2357
               Q++ P   Q P  P   PP S  P P  QP     HV      P PG     AS +
Sbjct: 585  AQTQLQIPVKTQQPNVPIPAPPSSQLPIPPSQPAQLALHV------PTPGKVQVQASQL 637



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 76/314 (24%), Positives = 106/314 (33%), Gaps = 48/314 (15%)

Query: 761  FPSSSGAMSVGMGQPPAQTGVSQG------QVPGAALPNPLNMLGPQASQLPCPPVTQSP 814
            F       S GM +   +  +  G      Q PGA    PL  L P A         Q  
Sbjct: 465  FKRQQAMPSTGMAEQSKRPRLEVGHQGVVFQHPGADAGVPLQQLMPTA---------QGG 515

Query: 815  LHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPT-PGSVPSATQ 873
            + PTP  A  A    S Q   P    P Q AA          S  TP P  PG +P A  
Sbjct: 516  MPPTPQAAQLAGQRQSQQQYDPSTGPPVQNAA----------SLHTPLPQLPGRLPPA-- 563

Query: 874  TQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPG---TPLSQAAASI 930
                PT   ++  Q   QPQ       +  P  +QQ   P+ A P      P SQ  A +
Sbjct: 564  --GVPTAALSSALQFAQQPQVVEAQTQLQIPVKTQQPNVPIPAPPSSQLPIPPSQ-PAQL 620

Query: 931  DNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQG 990
               VPTP  V    +        +P +   T    +   P P        S +      G
Sbjct: 621  ALHVPTPGKVQVQASQLS----SLPQMVASTRLPVDPAPPCPRPLPTSSTSSLAPVSGSG 676

Query: 991  -------ASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEES-SSNGTASQSTSPSQP 1042
                   +S V   +    +   P  V  + P V      + +S + N T+SQ +S    
Sbjct: 677  PGPSPARSSPVNRPSSATNKALSP--VTSRTPGVVASAPTKPQSPAQNATSSQDSSQDTL 734

Query: 1043 RKKIFKPEELRQAL 1056
             ++I    ++ Q +
Sbjct: 735  TEQITLENQVHQRI 748



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 61/217 (28%), Positives = 84/217 (38%), Gaps = 27/217 (12%)

Query: 757  PQNQFPSSSGAMSVG--MGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSP 814
            P+   P+++ A   G   G+PP  T  +  +   AA P        Q SQ         P
Sbjct: 1449 PRTAAPTTASAAPQGPLRGRPPIATFSANPEAKAAAAPF-------QTSQASASAPRHQP 1501

Query: 815  LHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQT 874
               +   AS A        TT    TP QP  P QP  P  ++GQ+  P    +PS  Q 
Sbjct: 1502 ASASSTAASPAHPAKLRAQTTAQASTPGQP--PPQPQAPSHAAGQSALPQRLVLPSQAQA 1559

Query: 875  Q--STPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQ----PPGTPLSQAAA 928
            +  S   V+ A  A +T       QP +  T Q    + T  H+Q      G PL Q   
Sbjct: 1560 RLPSGEVVKIAQLASITGPQSRVAQPETPVTLQFQGSKFTLSHSQLRQLTAGQPL-QLQG 1618

Query: 929  SIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQA 965
            S+   V  P      +   + PGP V    M+T +QA
Sbjct: 1619 SVLQIVSAP-----GQPYLRAPGPVV----MQTVSQA 1646



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 78/351 (22%), Positives = 115/351 (32%), Gaps = 54/351 (15%)

Query: 655  PVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQ 714
            P + QA  V+ P G    P +   + Q             Q  Q     +       +  
Sbjct: 2694 PQVSQATGVQLP-GKTITPAHFQLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTS 2752

Query: 715  MNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQA--------PAQSQFLPQNQFPSSSG 766
               +  + G A SP+++     +   H   M  Q         P Q+Q  P    P  + 
Sbjct: 2753 QVQVPQIQGQAQSPAQIKAVGKLTPEHLIKMQKQKLQMPPQPPPPQAQSAP----PQPTA 2808

Query: 767  AMSVGMGQPPAQTGVSQGQV----PGAALPNPLNMLGPQASQLPCPPVTQSPLH-----P 817
             + V   QPP Q       V    PGA L     +   Q ++L   P +Q          
Sbjct: 2809 QVQVQTSQPPQQQSPQLTTVTAPRPGALLTGT-TVANLQVARLTRVPTSQLQAQGQMQTQ 2867

Query: 818  TPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPST----------PVSSSGQTPTPTPGS 867
             P PA  A   P +   + P      P   T P            P  ++GQT    P  
Sbjct: 2868 APQPAQVALAKPPV--VSVPAAVVSSPGVTTLPMNVAGISVAIGQPQKAAGQTVVAQPVH 2925

Query: 868  VPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTP------VHAQPPG- 920
            +    + +     Q A Q Q   QPQ    P +V    ++QQ  TP       +A  P  
Sbjct: 2926 MQQLLKLK-----QQAVQQQKAIQPQAAQGPAAVQQKITAQQITTPGAQQKVAYAAQPAL 2980

Query: 921  ------TPLSQAAASID-NRVPTPSSVASAETNSQQPGPDVPVLEMKTETQ 964
                  TP+SQA       +V T   VA      QQ  P   + ++ + +Q
Sbjct: 2981 KTQFLTTPISQAQKLAGAQQVQTQIQVAKLPQVVQQQTPVASIQQVASASQ 3031



 Score = 41.6 bits (96), Expect = 0.010
 Identities = 80/320 (25%), Positives = 110/320 (34%), Gaps = 70/320 (21%)

Query: 2091 PQPGMHQQPSLQNLNAMQAGV------PRPGVPPQQ---QAMGGLNPQGQALNIMNPGHN 2141
            P  GM +Q     L     GV         GVP QQ    A GG+ P  QA         
Sbjct: 472  PSTGMAEQSKRPRLEVGHQGVVFQHPGADAGVPLQQLMPTAQGGMPPTPQAA-------- 523

Query: 2142 PNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGG 2201
                            QL  Q+Q QQQ         Q +A +   +        PQ PG 
Sbjct: 524  ----------------QLAGQRQSQQQYDPSTGPPVQNAASLHTPL--------PQLPGR 559

Query: 2202 YPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLG---QMGQPGLGADSTPNIQQALQQRIL 2258
             PPA      +     LQ +   Q+     QL    +  QP +   + P+ Q  +     
Sbjct: 560  LPPAGVPTAALSS--ALQFAQQPQVVEAQTQLQIPVKTQQPNVPIPAPPSSQLPIPPS-- 615

Query: 2259 QQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQS 2318
            Q  Q+   + +PG+    + Q          S LP    +T L      P P   P P S
Sbjct: 616  QPAQLALHVPTPGKVQVQASQ---------LSSLPQMVASTRLPVDPAPPCP--RPLPTS 664

Query: 2319 QPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMA-SSIDQGHLGNPEQSAMLPQLNTP 2377
                 +P     P PSP   SP      P  A   A S +     G    +   PQ  +P
Sbjct: 665  STSSLAPVSGSGPGPSPARSSPVN---RPSSATNKALSPVTSRTPGVVASAPTKPQ--SP 719

Query: 2378 SRSALSSELSLVGDTTGDTL 2397
            +++A SS+     D++ DTL
Sbjct: 720  AQNATSSQ-----DSSQDTL 734



 Score = 40.8 bits (94), Expect = 0.016
 Identities = 50/214 (23%), Positives = 75/214 (35%), Gaps = 27/214 (12%)

Query: 812  QSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSA 871
            + P HP PPP+  A   PS             P+AP  PS  +       +P  G   + 
Sbjct: 27   EQPAHPNPPPSPAAPFAPS-----------ASPSAPQSPSYQIQQL-MNRSPATGQNVNI 74

Query: 872  TQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATP--QSSQQQPTPVHAQPP----GTPLSQ 925
            T     P V    Q  + P P      PS  +P  Q S Q     H  P      +PLSQ
Sbjct: 75   TLQSVGPVVGGNQQITLAPLPL-----PSPTSPGFQFSAQPRRFEHGSPSYIQVTSPLSQ 129

Query: 926  AAASIDNRVPTPS-SVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRS--E 982
               +     P+P    A     +  PGP + +          D      +    P S   
Sbjct: 130  QVQTQSPTQPSPGPGQALQNVRAGAPGPGLGLCSSSPTGGFVDASVLVRQISLSPSSGGH 189

Query: 983  MMEEDLQGASQVKEETDI-AEQKSEPMEVDEKKP 1015
             + +D  G +Q+ +   +  +    P+ V E++P
Sbjct: 190  FVFQDGSGLTQIAQGAQVQLQHPGTPITVRERRP 223



 Score = 40.0 bits (92), Expect = 0.028
 Identities = 42/148 (28%), Positives = 57/148 (38%), Gaps = 18/148 (12%)

Query: 808  PPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGS 867
            PP T +P   +  P     G P +   +      P+  A   P     +S   P   P S
Sbjct: 1448 PPRTAAPTTASAAPQGPLRGRPPIATFS----ANPEAKAAAAPFQTSQASASAPRHQPAS 1503

Query: 868  VPSATQTQSTPTVQAAAQAQVTPQPQTPVQP------PSVATPQSSQQQ----PTPVHAQ 917
               A+ T ++P   A  +AQ T Q  TP QP      PS A  QS+  Q    P+   A+
Sbjct: 1504 ---ASSTAASPAHPAKLRAQTTAQASTPGQPPPQPQAPSHAAGQSALPQRLVLPSQAQAR 1560

Query: 918  PPGTPLSQAAASIDNRVPTPSSVASAET 945
             P   + + A       P  S VA  ET
Sbjct: 1561 LPSGEVVKIAQLASITGP-QSRVAQPET 1587



 Score = 37.0 bits (84), Expect = 0.23
 Identities = 94/411 (22%), Positives = 140/411 (34%), Gaps = 74/411 (18%)

Query: 102  QAQGQPNSANMASLSAMGK---SPLSQGDSSAPSLPKQAASTSGPTPAASQALNPQAQKQ 158
            Q QGQ  S   A + A+GK     L +       +P Q      P P  +Q+  PQ   Q
Sbjct: 2758 QIQGQAQSP--AQIKAVGKLTPEHLIKMQKQKLQMPPQ------PPPPQAQSAPPQPTAQ 2809

Query: 159  VGLATSSPATSQTGPGICMNANFNQTHPGLLNSNSGHSLINQASQGQAQVMNGSLGAAGR 218
            V + TS P   Q+     + A      PG L   +G ++ N       +V    L A G+
Sbjct: 2810 VQVQTSQPPQQQSPQLTTVTA----PRPGAL--LTGTTVANLQVARLTRVPTSQLQAQGQ 2863

Query: 219  GRGAGMPYPTPAMQGASSSVLAETLTQVSPQMTGHAGLNTAQAGGMAKMGITGNTSPFGQ 278
                     T A Q A  ++    +  V   +    G+ T        M + G +   GQ
Sbjct: 2864 -------MQTQAPQPAQVALAKPPVVSVPAAVVSSPGVTT------LPMNVAGISVAIGQ 2910

Query: 279  PFSQAGGQPMGATGVNPQ--LASKQSMVNSLPTF-PTDIKNTSVTNVPNMSQMQTSVGIV 335
            P  +A GQ + A  V+ Q  L  KQ  V       P   +  +       +Q  T+ G  
Sbjct: 2911 P-QKAAGQTVVAQPVHMQQLLKLKQQAVQQQKAIQPQAAQGPAAVQQKITAQQITTPGAQ 2969

Query: 336  PTQAIATGPTADPEKRKLIQQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHM 395
               A A  P          Q     +  A K    +Q   +++   LP       V+   
Sbjct: 2970 QKVAYAAQPALK------TQFLTTPISQAQKLAGAQQVQTQIQVAKLP------QVVQQQ 3017

Query: 396  THCQAGKACQAILGSPASGIQNTIGSVGTGQQNATSLSNPNPIDPSSMQRAYAALGLPYM 455
            T              P + IQ           +A+  ++P  +   ++ +A AA G    
Sbjct: 3018 T--------------PVASIQQV--------ASASQQASPQTV---ALTQATAA-GQQVQ 3051

Query: 456  NQPQTQLQPQVPGQQPAQPQ--THQQMRTLNPLGNNPMNIPAGGITTDQQP 504
              P      QV  Q+  Q Q  T        P   NP  +PA   +  QQP
Sbjct: 3052 MIPAVTATAQVVQQKLIQQQVVTTASAPLQTPGAPNPAQVPASSDSPSQQP 3102



 Score = 36.2 bits (82), Expect = 0.40
 Identities = 75/365 (20%), Positives = 120/365 (32%), Gaps = 88/365 (24%)

Query: 2016 PSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQP 2075
            PS  PPR+ +P+          +P  P + +  +    +NP+  AA    +T++  A+ P
Sbjct: 1444 PSTHPPRTAAPTTAS------AAPQGPLRGRPPIATFSANPEAKAAAAPFQTSQASASAP 1497

Query: 2076 GMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNI 2135
              QP     +         +  Q + Q           PG PP         PQ QA   
Sbjct: 1498 RHQPASASSTAASPAHPAKLRAQTTAQ--------ASTPGQPP---------PQPQA--- 1537

Query: 2136 MNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQ 2195
              P H    +++ PQ      R +L  Q Q +    +  +  Q    +A       +  Q
Sbjct: 1538 --PSHAAGQSAL-PQ------RLVLPSQAQARLPSGEVVKIAQ----LASITGPQSRVAQ 1584

Query: 2196 PQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQ 2255
            P+ P                L  QGS      +Q+ QL   GQP                
Sbjct: 1585 PETP--------------VTLQFQGSKFTLSHSQLRQL-TAGQP---------------- 1613

Query: 2256 RILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPR 2315
             +  Q  + Q + +PGQP   +P   ++    QA  + G          + S  P   P 
Sbjct: 1614 -LQLQGSVLQIVSAPGQPYLRAPGPVVMQTVSQAGAVHG---------ALGSKPPAGGPS 1663

Query: 2316 PQSQPPHSSPSPRI--------QPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQ 2367
            P    P      R+        +P  +    SP  G         +   +DQ +L N  +
Sbjct: 1664 PAPLTPQVGVPGRVAVNALAVGEPGTASKPASPIGGPTQEEKTRLLKERLDQIYLVNERR 1723

Query: 2368 SAMLP 2372
             +  P
Sbjct: 1724 CSQAP 1728



 Score = 35.8 bits (81), Expect = 0.52
 Identities = 73/315 (23%), Positives = 119/315 (37%), Gaps = 50/315 (15%)

Query: 90   SASSPVQQGLGGQAQGQPNSANMASLSAMGKSPLSQGDSSAPSLPKQAASTSGPTPAASQ 149
            +AS+  Q  L G+      SAN  + +A      SQ  +SAP     +AS++  +PA   
Sbjct: 1456 TASAAPQGPLRGRPPIATFSANPEAKAAAAPFQTSQASASAPRHQPASASSTAASPAHPA 1515

Query: 150  ALNPQAQKQVGLATSSPATSQTGPGICMNANFNQTHPGLLNSNSGHSLINQ----ASQGQ 205
             L  Q   Q       P                   P   +  +G S + Q     SQ Q
Sbjct: 1516 KLRAQTTAQASTPGQPP-----------------PQPQAPSHAAGQSALPQRLVLPSQAQ 1558

Query: 206  AQVMNGSLGAAGRGRGAGMPYPTPAMQGASSSVLAETLTQVSPQMTG------HAGLNTA 259
            A++ +G +    +           ++ G  S V A+  T V+ Q  G      H+ L   
Sbjct: 1559 ARLPSGEVVKIAQ---------LASITGPQSRV-AQPETPVTLQFQGSKFTLSHSQLRQL 1608

Query: 260  QAGGMAKM--GITGNTSPFGQPFSQAGGQPMGATGVNPQLASKQSMVNSLPTF--PTDIK 315
             AG   ++   +    S  GQP+ +A G  +  T    Q  +    + S P    P+   
Sbjct: 1609 TAGQPLQLQGSVLQIVSAPGQPYLRAPGPVVMQT--VSQAGAVHGALGSKPPAGGPSPAP 1666

Query: 316  NTSVTNVPNMSQMQT-SVGIVPTQAIATGPTADP---EKRKLIQQQL--VLLLHAHKC-Q 368
             T    VP    +   +VG   T +    P   P   EK +L++++L  + L++  +C Q
Sbjct: 1667 LTPQVGVPGRVAVNALAVGEPGTASKPASPIGGPTQEEKTRLLKERLDQIYLVNERRCSQ 1726

Query: 369  RREQANGEVRACSLP 383
                    +R C+LP
Sbjct: 1727 APVYGRDLLRICALP 1741



 Score = 35.8 bits (81), Expect = 0.52
 Identities = 49/203 (24%), Positives = 69/203 (33%), Gaps = 18/203 (8%)

Query: 1844 LPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSP-----VSMSPAGFPSVARTQPPTTVSTG 1898
            L + T+A   TP Q P  PQ P   A     P      S + A  PS    +     S  
Sbjct: 1517 LRAQTTAQASTPGQPPPQPQAPSHAAGQSALPQRLVLPSQAQARLPSGEVVKIAQLASIT 1576

Query: 1899 KPTSQVPAPPPPA----QPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPG 1954
             P S+V  P  P     Q     +  ++  +  A Q   L    +     PG+  +  PG
Sbjct: 1577 GPQSRVAQPETPVTLQFQGSKFTLSHSQLRQLTAGQPLQLQGSVLQIVSAPGQPYLRAPG 1636

Query: 1955 SQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPR 2014
                 V   V +   V G +    P G    APL  Q  +PG       +   A   G  
Sbjct: 1637 ---PVVMQTVSQAGAVHGALGSKPPAGGPSPAPLTPQVGVPG------RVAVNALAVGEP 1687

Query: 2015 MPSVQPPRSISPSALQDLLRTLK 2037
              + +P   I     ++  R LK
Sbjct: 1688 GTASKPASPIGGPTQEEKTRLLK 1710



 Score = 35.8 bits (81), Expect = 0.52
 Identities = 34/106 (32%), Positives = 43/106 (40%), Gaps = 12/106 (11%)

Query: 2252 ALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPV 2311
            A +++ L  QQ  QQ  +  QP P  PQ      QP    LP  Q A S   Q  +  P 
Sbjct: 2486 AKEKKALADQQKAQQ-PAVAQPPPPQPQPPPPPQQPPPP-LPQPQAAGS---QPPAGPPA 2540

Query: 2312 QSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSI 2357
              P+PQ       P P+ QPQP       Q      G A  +A +I
Sbjct: 2541 VQPQPQ-------PQPQTQPQPVQAPAKAQPAITTGGSAAVLAGTI 2579



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 32/126 (25%), Positives = 48/126 (38%), Gaps = 14/126 (11%)

Query: 1811 KLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQ--QPSTPQTPQPP 1868
            KL+  ++   +Q  Q    R     + + P+ + P+  SA P  P +   P    +  P 
Sbjct: 1420 KLKASRLFQPVQYGQKPEGRTVAFPSTHPPRTAAPTTASAAPQGPLRGRPPIATFSANPE 1479

Query: 1869 AQPQPSPVSMSPAGFPSVARTQPPTTVSTG-----------KPTSQVPAPPPPAQPPPAA 1917
            A+   +P   S A   S  R QP +  ST            + T+Q   P  P   P A 
Sbjct: 1480 AKAAAAPFQTSQAS-ASAPRHQPASASSTAASPAHPAKLRAQTTAQASTPGQPPPQPQAP 1538

Query: 1918 VEAARQ 1923
              AA Q
Sbjct: 1539 SHAAGQ 1544



 Score = 34.7 bits (78), Expect = 1.2
 Identities = 48/194 (24%), Positives = 66/194 (34%), Gaps = 28/194 (14%)

Query: 768  MSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQL--PCPPVTQSPLHPTPPPASTA 825
            M+ G   PP +  +  G  P    P   ++L         P PP+  + L      A   
Sbjct: 2433 MTAGKRSPPIKPLL--GMNPFQKNPKHASVLAESGINYDKPLPPIQVASLR-AERIAKEK 2489

Query: 826  AGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQ 885
              +   Q    P +  P P  P  P  P     Q P P P       Q Q+  +   A  
Sbjct: 2490 KALADQQKAQQPAVAQPPPPQPQPPPPPQ----QPPPPLP-------QPQAAGSQPPAGP 2538

Query: 886  AQVTPQPQ-------TPVQPPSVATPQ-----SSQQQPTPVHAQPPGTPLSQAAASIDNR 933
              V PQPQ        PVQ P+ A P      S+      +     GT +   A S +  
Sbjct: 2539 PAVQPQPQPQPQTQPQPVQAPAKAQPAITTGGSAAVLAGTIKTSVTGTSMPTGAVSGNVI 2598

Query: 934  VPTPSSVASAETNS 947
            V T + V +A   S
Sbjct: 2599 VNTIAGVPAATFQS 2612



 Score = 33.1 bits (74), Expect = 3.4
 Identities = 60/258 (23%), Positives = 82/258 (31%), Gaps = 59/258 (22%)

Query: 722 PGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGV 781
           P    +PS  P  P         +M ++PA                     GQ    T  
Sbjct: 38  PAAPFAPSASPSAPQSPSYQIQQLMNRSPAT--------------------GQNVNITLQ 77

Query: 782 SQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTP 841
           S G V G    N    L P    LP P  T      +  P     G PS    T P    
Sbjct: 78  SVGPVVGG---NQQITLAP----LPLPSPTSPGFQFSAQPRRFEHGSPSYIQVTSPLSQQ 130

Query: 842 PQPAAPTQPSTPVSSSGQ--------------TPTPTPGSVPSAT---QTQSTPT----- 879
            Q  +PTQPS     + Q              + +PT G V ++    Q   +P+     
Sbjct: 131 VQTQSPTQPSPGPGQALQNVRAGAPGPGLGLCSSSPTGGFVDASVLVRQISLSPSSGGHF 190

Query: 880 --------VQAAAQAQVTPQ-PQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASI 930
                    Q A  AQV  Q P TP+        Q   Q    +H   P +P +   A +
Sbjct: 191 VFQDGSGLTQIAQGAQVQLQHPGTPITVRERRPSQPHTQSGGTIHHLGPQSPAAAGGAGL 250

Query: 931 DNRVPTPSSVASAETNSQ 948
              + +PS + +A    Q
Sbjct: 251 -QPLASPSHITTANLPPQ 267



 Score = 33.1 bits (74), Expect = 3.4
 Identities = 22/82 (26%), Positives = 33/82 (40%)

Query: 2269 SPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPPHSSPSPR 2328
            +P Q NP        SG      LP  Q+A+  + ++       + + ++Q P  +  P 
Sbjct: 2449 NPFQKNPKHASVLAESGINYDKPLPPIQVASLRAERIAKEKKALADQQKAQQPAVAQPPP 2508

Query: 2329 IQPQPSPHHVSPQTGSPHPGLA 2350
             QPQP P    P    P P  A
Sbjct: 2509 PQPQPPPPPQQPPPPLPQPQAA 2530


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
            sapiens]
          Length = 1560

 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 218/924 (23%), Positives = 326/924 (35%), Gaps = 125/924 (13%)

Query: 85   GIGNVSASSPVQQGLGGQAQGQPNSANMASLS-----AMGKSPLSQGDSSAPSLPKQAAS 139
            G+GNV+   P+  GL G   G P  A  A+L       +G+  ++    ++  L KQ   
Sbjct: 202  GLGNVTLQ-PIP-GLQGLPNGSPGGATAATLGLAPIQVVGQPVMALNTPTSQLLAKQVP- 258

Query: 140  TSGPTPAASQALNPQAQKQVGLATSSPATSQTGPGICMNANFNQTHPGLLNSNSGHSLIN 199
             SG   +A+    P       +  +S   S  G G+ +  N +      LN NS      
Sbjct: 259  VSGYLASAAGPSEP-------VTLASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAG 311

Query: 200  QASQGQAQVMNGSLGAA-GRGRGAGMPYP------TPA-MQGASSSVLAETLTQVSPQMT 251
             AS          L  A G G    +P P      TP  +Q   + VL   L Q++P+  
Sbjct: 312  AASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPF 371

Query: 252  GHAGLNTAQAGGMAKMGITGNTSPFGQPFSQAGGQPMGATGVNPQLASKQSMVNSLPTFP 311
              AG         A + I G      Q       QP     +    A K      L  FP
Sbjct: 372  APAG---------ATLTIQGEPGALPQ-------QPKAPQNLTFMAAGKAGQNVVLSGFP 415

Query: 312  TDIKNTSVTNVPNMSQMQTSVGIVPTQAIATGPTADPEKRKLIQQQLVLLLHAHKCQRRE 371
                  +V   P      T+ G  P Q    G  + P    L+ Q   +++ A   Q   
Sbjct: 416  APALQANVFKQPPA----TTTGAAPPQP--PGALSKPMSVHLLNQGSSIVIPA---QHML 466

Query: 372  QANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQAILGSPASGIQNTIGSVGTGQQNATS 431
                +      P  + +   L+ +     G+   A   +P +G Q     + T Q  A  
Sbjct: 467  PGQNQFLLPGAPAVQ-LPQQLSALPANVGGQILAA--AAPHTGGQLIANPILTNQNLAGP 523

Query: 432  LSNPNPIDPSS-------MQRAYAALGLPYMNQ-PQTQLQPQVPGQQ---PAQPQ--THQ 478
            LS    + P S       +  A   +G P + Q P +     +P Q    PA P   T  
Sbjct: 524  LSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVL 583

Query: 479  QMRTLNPLGNNPMNIPAGGI-------TTDQQPPNLISESA--LPTSLGATNPLMNDGSN 529
            Q  TL P     +N P G +        T +  P L  + A   P ++    PL      
Sbjct: 584  QGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQ 643

Query: 530  SGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRME 589
            +       T   AAPP +T  +       +  L S    K+V    P+  P A+  +  +
Sbjct: 644  AQQPPQAPTPQAAAPPQATTPQP------SPGLASS-PEKIVLGQPPSATPTAILTQ--D 694

Query: 590  NLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGI-LGNQ-PAL 647
            +L  +  +       SA     +  + A  I       ++   +    +G  LG Q P  
Sbjct: 695  SLQMFLPQERSQQPLSAEG--PHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDS 752

Query: 648  PAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAAS 707
             A  A  P IP A P++ P GP S P    Q   G +   P         + P  P++ S
Sbjct: 753  QASPAPAPQIPAAAPLKGP-GPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVS 811

Query: 708  ------PMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQF 761
                  P++      +  ++PG+ +  +++  PP    A      A  P Q    PQ+Q 
Sbjct: 812  RPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPP---ASNPAPTAPGPPQPPLRPQSQP 868

Query: 762  PSSSGAMSVGMGQPPAQTG--VSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTP 819
            P   G +      PP+ T   V+      + LP P     P   QL  PP       PTP
Sbjct: 869  PE--GPLPPAPHLPPSSTSSAVASSSETSSRLPAPT----PSDFQLQFPPSQGPHKSPTP 922

Query: 820  PPASTAAGMPSLQHTTPPG----MTPPQPAAPTQPSTPVSSSGQTPT-----PTPGSVPS 870
            PP       P+     PP     +T P PA P QP   +    Q P+        G  P+
Sbjct: 923  PPTLHLVPEPAAPPPPPPRTFQMVTTPFPALP-QPKALLERFHQVPSGIILQNKAGGAPA 981

Query: 871  ATQTQST--PTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQ--PPGTPLSQA 926
            A QT ++  P    AA   V+ Q      P    T  S    P P+ A   PP  P    
Sbjct: 982  APQTSTSLGPLTSPAASVLVSGQ-----APSGTPTAPSHAPAPAPMAATGLPPLLPAENK 1036

Query: 927  AASIDNRVPTPSSVASAETNSQQP 950
            A +  + +PT +   +A +   +P
Sbjct: 1037 AFA--SNLPTLNVAKAASSGPGKP 1058



 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 220/934 (23%), Positives = 325/934 (34%), Gaps = 190/934 (20%)

Query: 93  SPVQQGLGGQAQG--QP--------NSANMASLSAMGKSPLSQGDSSAPSLPKQAASTSG 142
           SP   G GG + G  QP          AN+   +   ++ L  G    P+L + A   +G
Sbjct: 84  SPATGGGGGGSGGADQPCDILQQSLQEANITEQTLEAEAELDLGPFQLPTL-QPADGGAG 142

Query: 143 PTPA---ASQALNPQAQKQVGLATSSPATSQTGPGICMNANFNQTHPGLLNSNSGHSLIN 199
           PT A   A+ A  PQA        S+      GP   +      TH  L+       ++N
Sbjct: 143 PTGAGGAAAVAAGPQAL----FPGSTDLLGLQGPPTVL------THQALVPPQD---VVN 189

Query: 200 QASQGQAQVMNGSLGAAGRGRGAGMPYPTPAMQG----ASSSVLAETLTQVSPQMTGHA- 254
           +A   Q  +    LG            P P +QG    +     A TL     Q+ G   
Sbjct: 190 KALSVQPFLQPVGLGNVTL-------QPIPGLQGLPNGSPGGATAATLGLAPIQVVGQPV 242

Query: 255 -GLNTAQAGGMAK-MGITGNTSPFGQPFSQAGGQPMGATGVNPQLASKQSMVNSLPTFPT 312
             LNT  +  +AK + ++G  +    P        + + GV+PQ A      N      T
Sbjct: 243 MALNTPTSQLLAKQVPVSGYLASAAGPSEPV---TLASAGVSPQGAGLVIQKNLSAAVAT 299

Query: 313 DIKNTSV----------TNVPNMSQMQTSVGI-------VPTQAIATGPTA-DPEKRKLI 354
            +   SV          T  P+   +  + G+        P   +   PT   P+   ++
Sbjct: 300 TLNGNSVFGGAGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVL 359

Query: 355 QQQLVLLLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQAIL--GSPA 412
             +L  L              +    +LP          ++T   AGKA Q ++  G PA
Sbjct: 360 PPKLYQLTPKPFAPAGATLTIQGEPGALPQ---QPKAPQNLTFMAAGKAGQNVVLSGFPA 416

Query: 413 SGIQNTIGSVGTGQQNATSLSNPNPIDPSSMQRAYAALGLPYMNQPQTQLQPQVPGQQ-- 470
             +Q  +      Q  AT+     P  P ++ +  +   L   +      Q  +PGQ   
Sbjct: 417 PALQANVFK----QPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQF 472

Query: 471 --PAQP--QTHQQMRTLNPLGNNPMNIPAGGITTDQQPPNLISESALPTSLGA--TNPLM 524
             P  P  Q  QQ+  L      P N+  GG          I  +A P + G    NP++
Sbjct: 473 LLPGAPAVQLPQQLSAL------PANV--GG---------QILAAAAPHTGGQLIANPIL 515

Query: 525 NDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALK 584
              +N    G LS  P  AP S          H    L +  +     A+F  P   A  
Sbjct: 516 ---TNQNLAGPLSLGPVLAPHSGA--------HSAHILSAAPIQVGQPALFQMPVSLAAG 564

Query: 585 DRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQ 644
               ++  A A      + +          +L                      G++  Q
Sbjct: 565 SLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTP------------------DGLV--Q 604

Query: 645 PALPAPG---AQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPM 701
           PA PA     A P +  Q  P  PP     LP+   Q                Q PQAP 
Sbjct: 605 PATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQ------------QPPQAPT 652

Query: 702 GPRAASPMNHSVQMNSMGSVPGMAISPSR--MPQPPNMMGAHTNNMMAQAPAQSQFLPQ- 758
            P+AA+P   +    S    PG+A SP +  + QPP+     T   +    +   FLPQ 
Sbjct: 653 -PQAAAPPQATTPQPS----PGLASSPEKIVLGQPPSA----TPTAILTQDSLQMFLPQE 703

Query: 759 -NQFPSSSG-------AMSVGMGQPPAQ-----TGVSQG-----QVPGA-ALPNPLNMLG 799
            +Q P S+        A  +    PPAQ     T V++G     Q P + A P P   + 
Sbjct: 704 RSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQI- 762

Query: 800 PQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQ 859
           P A+ L  P  + SP  P   P   +  +PS   T PP   P +P + ++P +       
Sbjct: 763 PAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPC 822

Query: 860 TPTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQ-PTPVHAQP 918
            P   P ++P     Q+   V   A     P P  P  P     PQS   + P P     
Sbjct: 823 PPPQAPPTLPGIFVIQNQLGVPPPAS---NPAPTAPGPPQPPLRPQSQPPEGPLPPAPHL 879

Query: 919 PGTPLSQAAASIDNRVPTPSSVASAETNSQQPGP 952
           P +  S A AS            S+ET+S+ P P
Sbjct: 880 PPSSTSSAVAS------------SSETSSRLPAP 901



 Score = 75.1 bits (183), Expect = 8e-13
 Identities = 106/399 (26%), Positives = 144/399 (36%), Gaps = 68/399 (17%)

Query: 644 QPALPAPGAQPPVIPQA----QPVRPPNGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQ- 698
           QP     GA PP  P A      V   N   S+ +    +  G N F       VQLPQ 
Sbjct: 426 QPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQ 485

Query: 699 -------------APMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNM 745
                        A   P     +  +  + +      +++ P   P      GAH+ ++
Sbjct: 486 LSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHS----GAHSAHI 541

Query: 746 MAQAPAQSQFLPQNQFPSSSGAMSVG-MGQP----PAQTGVSQG-QVPGAA---LPNPLN 796
           ++ AP Q       Q P S  A S+    QP    PA T V QG  +P +A   L  P  
Sbjct: 542 LSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDG 601

Query: 797 MLGPQ----ASQLPCPPVTQSPLHPTPPPASTAA--GMPSLQHTTPPGMTPPQPAAPTQP 850
           ++ P     A+    P +T  P    PP  ST    G+   Q   PP    PQ AAP Q 
Sbjct: 602 LVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQA 661

Query: 851 STPVSSSGQTPTP-------TPGSVPSATQTQST------------------PTVQAAAQ 885
           +TP  S G   +P        P + P+A  TQ +                  P +   A 
Sbjct: 662 TTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPAS 721

Query: 886 AQVTPQPQTPVQPPSVATP--QSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASA 943
             V+  P  P Q P+ ATP  + +   P    +Q    P  Q  A+   + P PSS  S 
Sbjct: 722 VIVSAPP--PAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSS--SP 777

Query: 944 ETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSE 982
               Q P  D P L     T+     P   +S   P SE
Sbjct: 778 SLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSE 816



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 132/570 (23%), Positives = 194/570 (34%), Gaps = 106/570 (18%)

Query: 1849 SAPPGTPTQQP--------STPQTPQP---------PAQPQPS-----------PVSMSP 1880
            SAP GTP+ QP        S+P  P P         P QP+P+           P   +P
Sbjct: 314  SAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAP 373

Query: 1881 AGFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNIN 1940
            AG          T    G+P +    P  P      A   A Q    +       + N+ 
Sbjct: 374  AG---------ATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVF 424

Query: 1941 NSMPPGRTGMG---TPGSQMAPVSLNVPRPNQVSGPVMPS--MPPGQWQQAPLPQQQPMP 1995
               P   TG      PG+   P+S+++   NQ S  V+P+  M PGQ        Q  +P
Sbjct: 425  KQPPATTTGAAPPQPPGALSKPMSVHL--LNQGSSIVIPAQHMLPGQ-------NQFLLP 475

Query: 1996 GLPRPVISMQAQA--AVAGPRMPSVQPPRSISPSALQDLL--RTLKSPSS------PQQQ 2045
            G P   +  Q  A  A  G ++ +   P +        +L  + L  P S      P   
Sbjct: 476  GAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSG 535

Query: 2046 QQVLNILKSNP-QLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNL 2104
                +IL + P Q+    + Q      A     Q QP            G+   PS   +
Sbjct: 536  AHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAM 595

Query: 2105 NAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMN----PGHNPNMASMNPQYREMLRRQLL 2160
                 G+ +P  P            G+A  ++     P   P +++  P   +  + Q  
Sbjct: 596  LNTPDGLVQPATPAA--------ATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQP 647

Query: 2161 QQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQG 2220
             Q    Q     Q    Q S G+A   +   +    Q P   P A+  Q  +Q  LP Q 
Sbjct: 648  PQAPTPQAAAPPQATTPQPSPGLA---SSPEKIVLGQPPSATPTAILTQDSLQMFLP-QE 703

Query: 2221 SSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQ 2280
             S   ++A+   L     P     S P   Q                     P P +P  
Sbjct: 704  RSQQPLSAEGPHL---SVPASVIVSAPPPAQ--------------------DPAPATPVA 740

Query: 2281 HMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQP--PHSSPSPRIQPQPSPHHV 2338
                  PQA   P  Q + + + Q+ + AP++ P P S P  PH +P       PSPH  
Sbjct: 741  KGAGLGPQA---PDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPT 797

Query: 2339 SPQTGSPHPGLAVTMASSIDQGHLGNPEQS 2368
             P +  P    +V+   S    H   P Q+
Sbjct: 798  RPPSRPPSRPQSVSRPPSEPPLHPCPPPQA 827



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 137/611 (22%), Positives = 203/611 (33%), Gaps = 143/611 (23%)

Query: 1842 QSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQ--------PSPVSMSPAGFPSVART---- 1889
            Q  P P +    T T Q      PQ P  PQ         +  ++  +GFP+ A      
Sbjct: 365  QLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVF 424

Query: 1890 -QPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRT 1948
             QPP T      T   P  PP A   P +V    Q        QH+     N  + PG  
Sbjct: 425  KQPPATT-----TGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQ-NQFLLPGAP 478

Query: 1949 GMGTP----------GSQMAPVSLNVPRPNQVSGPVM------------PSMPPGQWQQ- 1985
             +  P          G Q+   +        ++ P++            P + P      
Sbjct: 479  AVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHS 538

Query: 1986 ------APLPQQQP----MP-GLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLR 2034
                  AP+   QP    MP  L    +  Q+Q A AGP   +V    ++ PSA+  +L 
Sbjct: 539  AHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVA-MLN 597

Query: 2035 T---LKSPSSPQ----QQQQVLNILKSN--PQLMAAFIKQRTAKYVANQPGMQPQPGLQS 2085
            T   L  P++P     +   VL +  +   P  ++  +     +  A QP   P P   +
Sbjct: 598  TPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAA 657

Query: 2086 QPGM---QPQPGMHQQPSLQNLNAMQAGVPRPGVP--------PQQQAMGGLNPQGQALN 2134
             P     QP PG+   P    L    +  P   +         PQ+++   L+ +G  L+
Sbjct: 658  PPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLS 717

Query: 2135 IMN--------PGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAG- 2185
            +          P  +P  A+       + +   L  Q    Q       Q   +A + G 
Sbjct: 718  VPASVIVSAPPPAQDPAPAT------PVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGP 771

Query: 2186 --------------GMAGHGQFQQPQGPGGYPPAMQQQ-QRMQQHLPLQGSSMGQMAAQM 2230
                          G + H     P  P   PP+  Q   R     PL      Q    +
Sbjct: 772  GPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTL 831

Query: 2231 GQL----GQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNP-MSPQQHMLSG 2285
              +     Q+G P   ++  P                     +PG P P + PQ     G
Sbjct: 832  PGIFVIQNQLGVPPPASNPAPT--------------------APGPPQPPLRPQSQPPEG 871

Query: 2286 Q-PQASHLP----GQQIATSLSNQVRSPAPV----QSPRPQSQPPHSSPSPRIQPQPSPH 2336
              P A HLP       +A+S     R PAP     Q   P SQ PH SP+P     P   
Sbjct: 872  PLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTP-----PPTL 926

Query: 2337 HVSPQTGSPHP 2347
            H+ P+  +P P
Sbjct: 927  HLVPEPAAPPP 937



 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 66/293 (22%), Positives = 98/293 (33%), Gaps = 22/293 (7%)

Query: 1840 PQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMS-----PAGFPSVARTQPPTT 1894
            P  S   P  AP G     PS P   +PP++P   P S+S     P   P      PPT 
Sbjct: 773  PSSSPSLPHQAPLGDSPHLPS-PHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTL 831

Query: 1895 VSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPG 1954
                   +Q+  PPP + P P A     Q     Q Q     +     +PP  T      
Sbjct: 832  PGIFVIQNQLGVPPPASNPAPTA-PGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVAS 890

Query: 1955 SQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQ----PMPGLPRPVISMQAQAAV 2010
            S      L  P P+       PS  P    ++P P       P P  P P      Q   
Sbjct: 891  SSETSSRLPAPTPSDFQLQFPPSQGP---HKSPTPPPTLHLVPEPAAPPPPPPRTFQMVT 947

Query: 2011 AGPRMPSVQPPRSISPSALQ---DLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRT 2067
                 P++  P+++     Q    ++   K+  +P   Q   ++        +  +  + 
Sbjct: 948  T--PFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQA 1005

Query: 2068 AKYVANQPGMQPQPGLQSQPGMQP-QPGMHQ--QPSLQNLNAMQAGVPRPGVP 2117
                   P   P P   +  G+ P  P  ++    +L  LN  +A    PG P
Sbjct: 1006 PSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKP 1058



 Score = 48.5 bits (114), Expect = 8e-05
 Identities = 117/603 (19%), Positives = 199/603 (33%), Gaps = 116/603 (19%)

Query: 440  PSSMQRAYAALGLPYMNQPQTQLQP------------QVPGQQPAQPQTHQQMRTLNPLG 487
            PS +     A G P   Q  T L P            Q P   P  P        +   G
Sbjct: 967  PSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATG 1026

Query: 488  NNPMNIPAGGITTDQQPPNLISESALPTSLGATNPLMNDGSNSGNIGTLSTIPTAAPPSS 547
              P+ +PA         P L    A  +  G  + L  +   SG    L   PT  P   
Sbjct: 1027 LPPL-LPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSG----LKKPPTLQPSKE 1081

Query: 548  TGVRKGWHEHVTQDLRSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESAN 607
                +  H+H     +  ++H   +  FP+ + A      +  L+ Y       +Y+ A 
Sbjct: 1082 ACFLEHLHKH-----QGSVLHPDYKTAFPSFEDA------LHRLLPY------HVYQGAL 1124

Query: 608  SRDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPN 667
                 YH + E+   +  +L ++ ++ L+K  +L  + +     +   V+     ++   
Sbjct: 1125 PSPSDYHKVDEEFETVSTQLLKRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEEK 1184

Query: 668  GPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAIS 727
              L+L     +        +  SLG          P AAS   H +     G  P  + +
Sbjct: 1185 TTLALDKQLAKEKPDEYVSSSRSLGL---------PIAASSEGHRLP----GHGPLSSSA 1231

Query: 728  PSRMPQPPNMM---------GAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSV-------G 771
            P    QPP  +         GA  +  +  A A S     +   S++ ++          
Sbjct: 1232 PGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPS 1291

Query: 772  MGQPPAQTGVSQGQV-------PGAALPNPLNMLGPQASQLPCPP-----VTQSPLHPTP 819
              +PP +T  ++ ++         A L   ++         P PP     V + P  P P
Sbjct: 1292 RNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPP 1351

Query: 820  PPASTAAGMPSLQHTTPPGMTP---PQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQS 876
            PP  T     ++ H  PP   P   P   AP  P  P+  + +     PG+       + 
Sbjct: 1352 PPPPTGQMNGTVDH--PPPAAPERKPLGTAPHCPRLPLRKTYRENVGGPGA------PEG 1403

Query: 877  TPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRV-- 934
            TP  +A                      +     P P       + L +  A++++ +  
Sbjct: 1404 TPAGRA----------------------RGGSPAPLPAKVDEATSGLIRELAAVEDELYQ 1441

Query: 935  -----PTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGE-SKGEPRSEMMEEDL 988
                 P P   ASA   +  P  + P L      ++E  + D    S   P+ + + E L
Sbjct: 1442 RMLKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHL 1501

Query: 989  QGA 991
            Q A
Sbjct: 1502 QSA 1504



 Score = 45.1 bits (105), Expect = 9e-04
 Identities = 61/250 (24%), Positives = 91/250 (36%), Gaps = 55/250 (22%)

Query: 1840 PQQSLPSPTSAPPGTPTQQPST--PQTPQPPAQ---------------------PQPSP- 1875
            P  S P+PT+  P  P  +P +  P+ P PPA                      P P+P 
Sbjct: 845  PPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPS 904

Query: 1876 ---VSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPP--------AQPPPAAVEAARQI 1924
               +   P+  P  + T PPT     +P     APPPP          P PA  +    +
Sbjct: 905  DFQLQFPPSQGPHKSPTPPPTLHLVPEPA----APPPPPPRTFQMVTTPFPALPQPKALL 960

Query: 1925 EREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQ 1984
            ER  Q    +   N     P        P +  +   L  P  + +     PS  P    
Sbjct: 961  ERFHQVPSGIILQNKAGGAP------AAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPS 1014

Query: 1985 QAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSIS-----PSALQ--DLLRTLK 2037
             AP P      GLP P++  + +A  +   +P++   ++ S     PS LQ    L  LK
Sbjct: 1015 HAPAPAPMAATGLP-PLLPAENKAFAS--NLPTLNVAKAASSGPGKPSGLQYESKLSGLK 1071

Query: 2038 SPSSPQQQQQ 2047
             P + Q  ++
Sbjct: 1072 KPPTLQPSKE 1081



 Score = 32.7 bits (73), Expect = 4.4
 Identities = 27/88 (30%), Positives = 34/88 (38%), Gaps = 20/88 (22%)

Query: 1891 PPTTVSTGKPTSQVPAPPPPA--------QPPPAAVE-----AARQIEREAQQQQHLYRV 1937
            PP T+   +P  + P PPPP          PPPAA E      A    R   ++   YR 
Sbjct: 1336 PPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRK--TYRE 1393

Query: 1938 NIN-----NSMPPGRTGMGTPGSQMAPV 1960
            N+         P GR   G+P    A V
Sbjct: 1394 NVGGPGAPEGTPAGRARGGSPAPLPAKV 1421



 Score = 32.7 bits (73), Expect = 4.4
 Identities = 48/189 (25%), Positives = 65/189 (34%), Gaps = 45/189 (23%)

Query: 775  PPAQTGVSQGQV----PGAALPNPLNMLGPQASQLPCPPVTQS----PLHPTPPPASTAA 826
            PP  TG   G V    P A    PL    P   +LP     +     P  P   PA  A 
Sbjct: 1352 PPPPTGQMNGTVDHPPPAAPERKPLGT-APHCPRLPLRKTYRENVGGPGAPEGTPAGRAR 1410

Query: 827  G-----MPSLQHTTPPGMT------------------PPQPAAPTQPSTPVSSSGQTPTP 863
            G     +P+       G+                   PP+PAA     T     G     
Sbjct: 1411 GGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGPPPEPAASAAQGT-----GDPDWE 1465

Query: 864  TPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQ--PPSVATPQSSQQQP--TPV----H 915
             PG  P+  +   +P V  A+ +  +PQ  T  +    ++ +  + QQ P  TP     H
Sbjct: 1466 APGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPH 1525

Query: 916  AQPPGTPLS 924
            A   GTP S
Sbjct: 1526 AASAGTPAS 1534


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 78.6 bits (192), Expect = 7e-14
 Identities = 103/382 (26%), Positives = 132/382 (34%), Gaps = 70/382 (18%)

Query: 645 PALPAP-GAQ----PPVIPQAQPVRPPNGPLSL-PVNRMQVSQGMNSFNPMSLGNVQLPQ 698
           P+ P P G Q    P V P  +   P  GPLS  P+     S   +   P SL  +  P 
Sbjct: 260 PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPP 319

Query: 699 APMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQ 758
           A    +A + +       +   +P   +SP   P P             QAP  +  LP 
Sbjct: 320 ATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP-------------QAPP-ALALPP 365

Query: 759 NQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPT 818
            Q P S          PPA   +S           PL    PQA       + Q+P  P 
Sbjct: 366 LQAPPS----------PPASPPLS-----------PLATPSPQAPNALAVHLLQAPFSPP 404

Query: 819 PPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTP 878
           P P   A   P       P  TPP  A P+  + P+      P   P S PSAT     P
Sbjct: 405 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS-PSATPPPQAP 463

Query: 879 TVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTP- 937
              AA   Q+   P  P  PP++ATP   Q  P+P  + P   P S +A+   + + TP 
Sbjct: 464 PPLAAPPLQLAKPP--PQAPPALATP-PLQALPSPPASFPGQAPFSPSASLPMSPLATPP 520

Query: 938 --------------------SSVASAETNSQQPGPDVPVLEMK-TETQAEDTEPDPGESK 976
                               S    A      PGPD  V   + T   A    P P  S 
Sbjct: 521 PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS- 579

Query: 977 GEPRSEMMEEDLQGASQVKEET 998
             P S +   DL G S     T
Sbjct: 580 --PSSTLSGPDLAGHSSSATST 599



 Score = 64.7 bits (156), Expect = 1e-09
 Identities = 84/324 (25%), Positives = 118/324 (36%), Gaps = 45/324 (13%)

Query: 1842 QSLPSPTSAPP-------GTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTT 1894
            Q+LPSP + PP       G+PT Q +    P PP  P  +P   +P   P++A   PP  
Sbjct: 313  QTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP---PALA--LPP-- 365

Query: 1895 VSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNIN-NSMPPGRTGMGTP 1953
                     + APP P   PP +  A    +       HL +   +    PP +     P
Sbjct: 366  ---------LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP 416

Query: 1954 GSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGP 2013
             S   PVS +   P+Q      PS+     Q  P P   P P  P      QA   +A P
Sbjct: 417  AS--PPVSPSATPPSQAP----PSLAAPPLQVPPSPPASP-PMSPSATPPPQAPPPLAAP 469

Query: 2014 RMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVAN 2073
             +   +PP    P+     L+ L SP +    Q   +   S P    A    +    +A 
Sbjct: 470  PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA- 528

Query: 2074 QPGMQPQPGLQSQPGMQ-----PQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNP 2128
             P +Q  P   + P +Q     P PG     S   L    A  P P  PP +     L+ 
Sbjct: 529  APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALA--PGPPPPPSRSPSSTLSG 586

Query: 2129 QGQALNIMNPGHNPNMASMNPQYR 2152
               A      GH+ +  S   + R
Sbjct: 587  PDLA------GHSSSATSTPEELR 604



 Score = 63.2 bits (152), Expect = 3e-09
 Identities = 77/296 (26%), Positives = 102/296 (34%), Gaps = 31/296 (10%)

Query: 1835 NTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTT 1894
            + R  P+         P G    +P     P+  A P   P+S SP   PS     P   
Sbjct: 249  SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS-----PSAP 303

Query: 1895 VSTGKPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPG 1954
             S   P S    P PPA PP    +A   +     Q  H +  +      P  + + TP 
Sbjct: 304  PSPSAPPSLQTLPSPPATPPS---QATTSLGSPTLQATHSFLPS------PPLSPLATPP 354

Query: 1955 SQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQ----------QQPMPGLPRPVISM 2004
             Q AP +L +P P Q + P  P+ PP      P PQ          Q P    P P +  
Sbjct: 355  PQ-APPALALP-PLQ-APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 411

Query: 2005 QAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKS-PSSPQQQQQVLNILKSNPQLMAAFI 2063
                  + P  PS  PP    PS     L+   S P+SP          ++ P L A  +
Sbjct: 412  PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 471

Query: 2064 KQRTAKYVANQPGMQPQPGLQSQPGMQPQ-PGMHQQPSLQNLNAMQAGVPRPGVPP 2118
              + AK     P     P LQ+ P      PG        +L       P P  PP
Sbjct: 472  --QLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 525



 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 98/375 (26%), Positives = 135/375 (36%), Gaps = 87/375 (23%)

Query: 637 KQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMNSFNPMS-----L 691
           K G     PA  APG   P  P +    PP  P +L   R+  + G     P++     +
Sbjct: 9   KAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAAL---RVLGAAGAVGRKPLAERAGGI 65

Query: 692 GNVQLPQAPMGPRAASPMNHSVQMNSMG--------SVPGMAISPSR-----MPQPPNMM 738
           G   +P++   PRA          +  G        + PG   SP R      P P    
Sbjct: 66  GGATIPES--APRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQK 123

Query: 739 GAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNML 798
           G   +     A  ++   P+     S+GA     G  P          P  A+       
Sbjct: 124 GLRISAEETVARGKATEAPKRS-ALSAGARRDTSGPTPG--------TPSPAMARRSRAA 174

Query: 799 GPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPST------ 852
           G +   LP P  +  P  PT  P  + +   + +H+T    T P PAA  +PS       
Sbjct: 175 GTEVG-LPRPAPSARPRPPTEGPRKSVSS--ASEHST----TEPSPAARRRPSAGGGLQR 227

Query: 853 PVS---SSGQTPTPTPG-SVPSATQTQSTPT---------VQAAAQAQVTPQPQ------ 893
           P S   SS  TP  +P  S PSA  T   P          +QA    QVTP  +      
Sbjct: 228 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 287

Query: 894 -----------TPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVAS 942
                      +P  PPS + P S Q  P+     PP TP SQA  S+ +  PT  +   
Sbjct: 288 GPLSSSPLATPSPSAPPSPSAPPSLQTLPS-----PPATPPSQATTSLGS--PTLQA--- 337

Query: 943 AETNSQQPGPDVPVL 957
             T+S  P P +  L
Sbjct: 338 --THSFLPSPPLSPL 350



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 67/251 (26%), Positives = 94/251 (37%), Gaps = 46/251 (18%)

Query: 727 SPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMG-QPPAQTGVSQGQ 785
           +PS  P+PP      T        + S+       P++    S G G Q PA   +S   
Sbjct: 184 APSARPRPP------TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA 237

Query: 786 VPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQ-- 843
            P   L +P    GP A   P     ++P HP+ P          LQ   PP +TPP+  
Sbjct: 238 TP---LSSPARS-GPSARGTP-----RAPAHPSQPKPK------GLQALRPPQVTPPRKD 282

Query: 844 -----------------PAAPTQPSTPVSSSGQTPTPTPGSVPS-ATQTQSTPTVQAAAQ 885
                            P+AP  PS P S   QT    P + PS AT +  +PT+QA   
Sbjct: 283 AAPALGPLSSSPLATPSPSAPPSPSAPPSL--QTLPSPPATPPSQATTSLGSPTLQATHS 340

Query: 886 AQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAET 945
              +P P +P+  P    P +    P      PP +P     A+   + P   +V   + 
Sbjct: 341 FLPSP-PLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQA 399

Query: 946 NSQQPGPDVPV 956
               P P  PV
Sbjct: 400 PFSPP-PSPPV 409



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 121/543 (22%), Positives = 166/543 (30%), Gaps = 76/543 (13%)

Query: 1854 TPTQQPSTPQTPQPPAQPQP----SPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPP 1909
            TP  +     TP+PP  P+P    +P ++   G       +P    + G   + +P   P
Sbjct: 16   TPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAP 75

Query: 1910 PAQP-----PPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSL-- 1962
             A P     PPA+       ER    +        +     G T  G  G +   +S   
Sbjct: 76   RAGPTRTSRPPASGRG----ERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEE 131

Query: 1963 NVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPR 2022
             V R      P   ++  G    A      P PG P P ++ +++A  AG  +   +P  
Sbjct: 132  TVARGKATEAPKRSALSAG----ARRDTSGPTPGTPSPAMARRSRA--AGTEVGLPRPAP 185

Query: 2023 SISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPG 2082
            S  P    +  R   S +S     +     +  P        QR A    +         
Sbjct: 186  SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL--QRPASRSLSSSATPLSSP 243

Query: 2083 LQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQGQALNIMNPGHNP 2142
             +S P  +  P     PS      +QA  P    PP++ A   L P   +         P
Sbjct: 244  ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAP 303

Query: 2143 NMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQ-GPGG 2201
               S  P          LQ           Q     GS  +    A H     P   P  
Sbjct: 304  PSPSAPPS---------LQTLPSPPATPPSQATTSLGSPTL---QATHSFLPSPPLSPLA 351

Query: 2202 YPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQ 2261
             PP   Q        PLQ       +  +  L         A  +P    AL   +LQ  
Sbjct: 352  TPP--PQAPPALALPPLQAPPSPPASPPLSPL---------ATPSPQAPNALAVHLLQ-- 398

Query: 2262 QMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQSPRPQSQPP 2321
                   +P  P P  P Q   S  P A                 SP    S  P SQ P
Sbjct: 399  -------APFSPPPSPPVQAPFS--PPA-----------------SPPVSPSATPPSQAP 432

Query: 2322 HSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSA 2381
             S  +P +Q  PSP    P + S  P        +     L  P   A  P L TP   A
Sbjct: 433  PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP-PALATPPLQA 491

Query: 2382 LSS 2384
            L S
Sbjct: 492  LPS 494



 Score = 40.0 bits (92), Expect = 0.028
 Identities = 30/95 (31%), Positives = 40/95 (42%), Gaps = 17/95 (17%)

Query: 1840 PQQSLPSPTSAPPGTPTQQPST--PQTP--QPPAQPQP---SPVSMSPAGFPSVARTQPP 1892
            P Q+LPSP ++ PG     PS   P +P   PP Q  P   +P+   P   P+    Q P
Sbjct: 488  PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP 547

Query: 1893 TTVSTGKPTSQV----------PAPPPPAQPPPAA 1917
                T  P + V          P PPPP    P++
Sbjct: 548  RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS 582



 Score = 33.1 bits (74), Expect = 3.4
 Identities = 44/212 (20%), Positives = 66/212 (31%), Gaps = 32/212 (15%)

Query: 784 GQVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQ 843
           G + GA +P      GP  +  P      S      PPA   +  P        G T P 
Sbjct: 63  GGIGGATIPESAPRAGPTRTSRP----PASGRGERAPPAKNTSPGPVSSPGRASGTTRPG 118

Query: 844 PA--------------------APTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAA 883
           P                     AP + +    +   T  PTPG+   A   +S      A
Sbjct: 119 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR-----A 173

Query: 884 AQAQV---TPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSV 940
           A  +V    P P    +PP+    +S          +P      + +A    + P   S+
Sbjct: 174 AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 233

Query: 941 ASAETNSQQPGPDVPVLEMKTETQAEDTEPDP 972
           +S+ T    P    P         A  ++P P
Sbjct: 234 SSSATPLSSPARSGPSARGTPRAPAHPSQPKP 265


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.128    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 117,061,519
Number of Sequences: 37866
Number of extensions: 7349393
Number of successful extensions: 124031
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 890
Number of HSP's successfully gapped in prelim test: 2687
Number of HSP's that attempted gapping in prelim test: 40047
Number of HSP's gapped (non-prelim): 45347
length of query: 2404
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2285
effective length of database: 13,741,464
effective search space: 31399245240
effective search space used: 31399245240
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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