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Search of human proteins with 239756393
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239756393 PREDICTED: hypothetical protein XP_002344913 [Homo
sapiens]
(422 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239756393 PREDICTED: hypothetical protein XP_002344913 [Homo ... 862 0.0
gi|239750914 PREDICTED: hypothetical protein XP_002347614 [Homo ... 664 0.0
gi|239745312 PREDICTED: hypothetical protein XP_002343435 [Homo ... 664 0.0
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 45 1e-04
gi|150170729 microtubule associated serine/threonine kinase 3 [H... 43 6e-04
gi|41281612 zinc finger protein 828 [Homo sapiens] 42 0.001
gi|27477109 itchy homolog E3 ubiquitin protein ligase [Homo sapi... 41 0.002
gi|7706635 cornulin [Homo sapiens] 41 0.002
gi|113413437 PREDICTED: hypothetical protein [Homo sapiens] 39 0.009
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 39 0.009
gi|169164483 PREDICTED: hypothetical protein [Homo sapiens] 39 0.012
gi|113414226 PREDICTED: hypothetical protein [Homo sapiens] 39 0.012
gi|110227615 echinoderm microtubule associated protein like 3 [H... 38 0.020
gi|169160983 PREDICTED: hypothetical protein [Homo sapiens] 37 0.026
gi|13994190 frizzled 8 [Homo sapiens] 37 0.026
gi|59806361 hypothetical protein LOC387104 [Homo sapiens] 37 0.034
gi|239756562 PREDICTED: hypothetical protein [Homo sapiens] 37 0.044
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 37 0.044
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 37 0.044
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi... 36 0.058
gi|239751535 PREDICTED: hypothetical protein [Homo sapiens] 36 0.058
gi|239746046 PREDICTED: hypothetical protein XP_002343643 [Homo ... 36 0.058
gi|87196343 PDZ domain containing 2 [Homo sapiens] 36 0.075
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 35 0.098
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens] 35 0.13
gi|239753839 PREDICTED: hypothetical protein [Homo sapiens] 35 0.13
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ... 35 0.13
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [... 35 0.13
gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens] 35 0.13
gi|169207782 PREDICTED: hypothetical protein [Homo sapiens] 35 0.17
>gi|239756393 PREDICTED: hypothetical protein XP_002344913 [Homo
sapiens]
Length = 422
Score = 862 bits (2228), Expect = 0.0
Identities = 422/422 (100%), Positives = 422/422 (100%)
Query: 1 MAPLSFPQLRRGLTLLEARGRRPGGKRGTEIRAVGEQLESWRSWRKDVAGCSSPTPIPEF 60
MAPLSFPQLRRGLTLLEARGRRPGGKRGTEIRAVGEQLESWRSWRKDVAGCSSPTPIPEF
Sbjct: 1 MAPLSFPQLRRGLTLLEARGRRPGGKRGTEIRAVGEQLESWRSWRKDVAGCSSPTPIPEF 60
Query: 61 GAAAPTKSALQVQVVPSSQAVEFGQHPGRGLQDRTQPTRIIRGCTVTSPSRQSETQITPA 120
GAAAPTKSALQVQVVPSSQAVEFGQHPGRGLQDRTQPTRIIRGCTVTSPSRQSETQITPA
Sbjct: 61 GAAAPTKSALQVQVVPSSQAVEFGQHPGRGLQDRTQPTRIIRGCTVTSPSRQSETQITPA 120
Query: 121 GGPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRR 180
GGPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRR
Sbjct: 121 GGPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRR 180
Query: 181 PARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSS 240
PARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSS
Sbjct: 181 PARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSS 240
Query: 241 VDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPR 300
VDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPR
Sbjct: 241 VDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPR 300
Query: 301 SLVAPSESGSAGKRRGTNGGATPRKSCDASGAWGGKAKAHGWAPLTAFLRRLHSALVGVK 360
SLVAPSESGSAGKRRGTNGGATPRKSCDASGAWGGKAKAHGWAPLTAFLRRLHSALVGVK
Sbjct: 301 SLVAPSESGSAGKRRGTNGGATPRKSCDASGAWGGKAKAHGWAPLTAFLRRLHSALVGVK 360
Query: 361 GGAGGAALTSLRAVPAREGGAGSRSEPREAARGQEPPLRHCRACLPQLSAMRSPGQGRPE 420
GGAGGAALTSLRAVPAREGGAGSRSEPREAARGQEPPLRHCRACLPQLSAMRSPGQGRPE
Sbjct: 361 GGAGGAALTSLRAVPAREGGAGSRSEPREAARGQEPPLRHCRACLPQLSAMRSPGQGRPE 420
Query: 421 GG 422
GG
Sbjct: 421 GG 422
>gi|239750914 PREDICTED: hypothetical protein XP_002347614 [Homo
sapiens]
Length = 492
Score = 664 bits (1712), Expect = 0.0
Identities = 349/431 (80%), Positives = 359/431 (83%), Gaps = 20/431 (4%)
Query: 1 MAPLSFPQLRRGLTLLEARGRRPGGKRGTEIRAVGEQLESWRSWRKDVAGCSSPTPIPEF 60
MAPLSFPQLRRGLTLLEARGRRPGGKRGTEIRAVGEQLESWRSWRKDVAGCSSPTPIPEF
Sbjct: 1 MAPLSFPQLRRGLTLLEARGRRPGGKRGTEIRAVGEQLESWRSWRKDVAGCSSPTPIPEF 60
Query: 61 GAAAPTKSALQVQVVPSSQAVEFGQHPGRGLQDRTQPTRIIRGCTVTSPSRQSETQITPA 120
GAAAPTKSALQVQVVPSSQAVEFGQHPGRGLQDRTQPTRIIRGCTVTSPSRQSETQITPA
Sbjct: 61 GAAAPTKSALQVQVVPSSQAVEFGQHPGRGLQDRTQPTRIIRGCTVTSPSRQSETQITPA 120
Query: 121 GGPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRR 180
GGPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRR
Sbjct: 121 GGPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRR 180
Query: 181 PARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSS 240
PARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSS
Sbjct: 181 PARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSS 240
Query: 241 VDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPR 300
VDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPR
Sbjct: 241 VDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPR 300
Query: 301 SLVAPSESGSAGKRRGTNGGATPRKSCDASGAWGGKAKA------HGWAPLTAFLRRLHS 354
SLVAPSESGSAG+R GTNG ATPR+ G K + H P F
Sbjct: 301 SLVAPSESGSAGRRGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRG- 359
Query: 355 ALVGVKGGAGG--AALTSLRAVPAREGGAGSRSEPREAARG-QEPPLRHCRACLPQLSAM 411
+GG GG A +T+ RA P R R++ A G PPL CLP +
Sbjct: 360 -----EGGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPL----PCLPPAAVC 410
Query: 412 RS-PGQGRPEG 421
+ G G P G
Sbjct: 411 HALAGAGAPGG 421
>gi|239745312 PREDICTED: hypothetical protein XP_002343435 [Homo
sapiens]
Length = 492
Score = 664 bits (1712), Expect = 0.0
Identities = 349/431 (80%), Positives = 359/431 (83%), Gaps = 20/431 (4%)
Query: 1 MAPLSFPQLRRGLTLLEARGRRPGGKRGTEIRAVGEQLESWRSWRKDVAGCSSPTPIPEF 60
MAPLSFPQLRRGLTLLEARGRRPGGKRGTEIRAVGEQLESWRSWRKDVAGCSSPTPIPEF
Sbjct: 1 MAPLSFPQLRRGLTLLEARGRRPGGKRGTEIRAVGEQLESWRSWRKDVAGCSSPTPIPEF 60
Query: 61 GAAAPTKSALQVQVVPSSQAVEFGQHPGRGLQDRTQPTRIIRGCTVTSPSRQSETQITPA 120
GAAAPTKSALQVQVVPSSQAVEFGQHPGRGLQDRTQPTRIIRGCTVTSPSRQSETQITPA
Sbjct: 61 GAAAPTKSALQVQVVPSSQAVEFGQHPGRGLQDRTQPTRIIRGCTVTSPSRQSETQITPA 120
Query: 121 GGPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRR 180
GGPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRR
Sbjct: 121 GGPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRR 180
Query: 181 PARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSS 240
PARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSS
Sbjct: 181 PARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSS 240
Query: 241 VDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPR 300
VDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPR
Sbjct: 241 VDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPR 300
Query: 301 SLVAPSESGSAGKRRGTNGGATPRKSCDASGAWGGKAKA------HGWAPLTAFLRRLHS 354
SLVAPSESGSAG+R GTNG ATPR+ G K + H P F
Sbjct: 301 SLVAPSESGSAGRRGGTNGVATPREKLGGKRGVGRKGQGTRLGAPHSLPPPPPFRTGRG- 359
Query: 355 ALVGVKGGAGG--AALTSLRAVPAREGGAGSRSEPREAARG-QEPPLRHCRACLPQLSAM 411
+GG GG A +T+ RA P R R++ A G PPL CLP +
Sbjct: 360 -----EGGGGGSRADVTAGRARPRRRRWEPLRAQRSGARPGAPAPPL----PCLPPAAVC 410
Query: 412 RS-PGQGRPEG 421
+ G G P G
Sbjct: 411 HALAGAGAPGG 421
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 45.1 bits (105), Expect = 1e-04
Identities = 80/335 (23%), Positives = 120/335 (35%), Gaps = 51/335 (15%)
Query: 108 SPSRQSETQITPAGGPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWP 167
SP +SE+ +P DS A+++ LR + G P+ + R P R
Sbjct: 1552 SPQERSESDSSP--------DSKAKTRTPLRQRSRS-GSSPEVDSKSRL-----SPRRSR 1597
Query: 168 NGFRPARQRRTRRPARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSL 227
+G P + + R RA + SP E P+ +P S R
Sbjct: 1598 SGSSPEVKDKPRAAPRAQSGSDSSP----------EPKAPAPRALPRRSRSGSSSKGRGP 1647
Query: 228 LSSHGSPGTIQSSVDIPSLTNTCAGGKDKTP-PFSQEVDDPHALSSPFFPK--------- 277
S GS T +SS + P + T G +P P ++ P SS P+
Sbjct: 1648 -SPEGSSST-ESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSR 1705
Query: 278 --QLGSLSLELPARLPTRCLPSPPRSLVAPSESGSAGKRRGTNGGATPRKSCDASGAWGG 335
+ S S E +R P R SP S P+E + +RR ++PR +
Sbjct: 1706 RSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRR--RSASSPRTKTTSRRGRSP 1763
Query: 336 KAKAHGWAPLTAFLRRLHSALVGVKGGAGGAALTS---------LRAVPAREGGAG--SR 384
K G + RR + + +G + TS R R GG+G SR
Sbjct: 1764 SPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSR 1823
Query: 385 SEPREAARGQEPPLRHCRACLPQLSAMRSPGQGRP 419
S R+ + R R+ P S RS + P
Sbjct: 1824 SPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSP 1858
Score = 39.3 bits (90), Expect = 0.007
Identities = 58/244 (23%), Positives = 89/244 (36%), Gaps = 30/244 (12%)
Query: 34 VGEQLESWRSWRKDVAGCSSPTPIPEFGAAAPTKSALQVQVVPSSQAVEFGQHPGRGLQD 93
+G++ S S DV +SP E ++ +K+ + P Q G P +
Sbjct: 1533 LGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRT---PLRQRSRSGSSPEVDSKS 1589
Query: 94 RTQPTRIIRGCTVTSPSRQSETQITPAGGPAAFCDSTAESK--------RQLRVGAEGKG 145
R P R G +SP + + + P + DS+ E K R+ R G+ KG
Sbjct: 1590 RLSPRRSRSG---SSPEVKDKPRAAPRAQSGS--DSSPEPKAPAPRALPRRSRSGSSSKG 1644
Query: 146 GGPQALGRGRRVNGPQGPDRWPNGFR-----PARQRRTRRPARALNSGQWSPGEGRRAAL 200
GP G + P+ P + R P + ++R P R S + SP R+A
Sbjct: 1645 RGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRR-RSSRSSPELTRKAR- 1702
Query: 201 GLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSP------GTIQSSVDIPSLTNTCAGGK 254
L S P + T R +RS S P + S P T G+
Sbjct: 1703 -LSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGR 1761
Query: 255 DKTP 258
+P
Sbjct: 1762 SPSP 1765
Score = 33.1 bits (74), Expect = 0.49
Identities = 78/348 (22%), Positives = 113/348 (32%), Gaps = 54/348 (15%)
Query: 21 RRPGGKRGTEIRAVGEQLESWRSWRKDVAGCSSPTPIPEFGAAAPTKSALQVQVVPSSQA 80
+RPG R + G RS R+ + SP + P + P+ +
Sbjct: 538 QRPGWSRSRNTQRRGRS----RSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRR 593
Query: 81 VEFGQHPGRGLQDRTQPTRIIRGCTVTSPSRQSETQITPAGGPAAFCDSTAESKRQLRVG 140
R + RT P R R + T R+S T+ P + S+ R
Sbjct: 594 SRSRTPTRRRSRSRT-PARRGRSRSRTPARRRSRTR-----SPVR---RRSRSRSPARRS 644
Query: 141 AEGKGGGPQALGRGR-RVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGEGRRAA 199
+ P GR R R +G R R + + R+R PAR S +P GR +
Sbjct: 645 GRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRS 704
Query: 200 LGLEEAGPSLEGIP--------SSEWDTFSRDKRSLLSSHGSPGTIQS--------SVDI 243
L G S P SSE SR + S+ SP +S S+
Sbjct: 705 RSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSS 764
Query: 244 P--------------SLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELP-- 287
P S ++ C K +TPP + P + S P
Sbjct: 765 PRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPK 824
Query: 288 --ARLPTR-----CLPSPPRSLVAPSESGSAGKRRGTNGGATP-RKSC 327
++ P+R P P P GS + TP R+SC
Sbjct: 825 QKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSC 872
Score = 29.3 bits (64), Expect = 7.0
Identities = 62/273 (22%), Positives = 90/273 (32%), Gaps = 49/273 (17%)
Query: 179 RRPARALNSGQWSPG----EGRRAALGLEEAGPSLEGIPS------SEWDTFSRDKRSLL 228
R P+R SG SPG G + L + P ++ IP SE D+ K
Sbjct: 1433 RTPSRRSRSGS-SPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPK---- 1487
Query: 229 SSHGSPGTIQSSVDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPA 288
+ +P S P L N C + + VD +P + S EL
Sbjct: 1488 ALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDV 1547
Query: 289 RLPTRCLPSPPRSLVAP-------------SESGSAGK---------RRGTNGGAT---- 322
+ P+ S +P S SGS+ + RR +G +
Sbjct: 1548 K-PSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKD 1606
Query: 323 -PRKSCDASGAWGGKAKAHGWAPLTAFLRRLHSALVGVKGGAGGAALTSLRAVP-----A 376
PR + A + AP A RR S G +S + P +
Sbjct: 1607 KPRAAPRAQSGSDSSPEPKAPAP-RALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKS 1665
Query: 377 REGGAGSRSEPREAARGQEPPLRHCRACLPQLS 409
R GSRS P + + PP R P+L+
Sbjct: 1666 RTARRGSRSSPEPKTKSRTPPRRRSSRSSPELT 1698
>gi|150170729 microtubule associated serine/threonine kinase 3 [Homo
sapiens]
Length = 1309
Score = 42.7 bits (99), Expect = 6e-04
Identities = 56/222 (25%), Positives = 77/222 (34%), Gaps = 41/222 (18%)
Query: 42 RSWRKDVAGCSSPTPIPEFGAAAPTKSALQVQVVPSSQAVEFGQHPGRGLQDRTQPTRII 101
RSW + C S + PE G + + + + +P + G G +P I+
Sbjct: 753 RSWTSSGSSCQSSSSQPERGPSPSLLNTISLDTMPKFAFSSEDEGVGPGPAGPKRPVFIL 812
Query: 102 RGCTVTSPSRQSETQITPAGGP------AAFCDSTAESKRQLR---VGAEGKGGGPQALG 152
E PA P + D+ A S +LR +GA P G
Sbjct: 813 -----------GEPDPPPAATPVMPKPSSLSADTAALSHARLRSNSIGARHSTPRPLDAG 861
Query: 153 RGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGEGRRAALGL------EEAG 206
RGRR+ GP+ P P + R + SG P +AL L G
Sbjct: 862 RGRRLGGPRDP-------APEKSRASSSGGSGGGSGGRVPKSASVSALSLIITADDGSGG 914
Query: 207 P--------SLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSS 240
P SL PSS + SRD + S P I SS
Sbjct: 915 PLMSPLSPRSLSSNPSSRDSSPSRDPSPVCGSLRPPIVIHSS 956
>gi|41281612 zinc finger protein 828 [Homo sapiens]
Length = 812
Score = 42.0 bits (97), Expect = 0.001
Identities = 67/313 (21%), Positives = 103/313 (32%), Gaps = 49/313 (15%)
Query: 53 SPTPIPEFGAAAPTKSALQVQVVPSSQAVEFGQHPGRGLQDRTQPTRIIRGCTVTSPSRQ 112
+P P PE A S + VP ++ + P Q + T+++P Q
Sbjct: 169 TPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQ 228
Query: 113 SETQITPAGGPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGR---RVNGPQ----GPDR 165
++ GP + +++ L E G P A R R P+ P
Sbjct: 229 KQSHFPETLGPPS---ASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSE 285
Query: 166 WPNGFRP--ARQRRTRRPARALNSGQWSPG-----------------------------E 194
P ++P A RRPA A++ G W PG
Sbjct: 286 SPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSP 345
Query: 195 GRRAALGLEEAGP--SLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCAG 252
G + GP + S+ W + S S S SP + +S P L T
Sbjct: 346 GPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGP--PELRKTAPT 403
Query: 253 GKDK----TPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPRSLVAPSES 308
+ PP S E+ P SP GS L P+ P SP + +P+
Sbjct: 404 LSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASL 463
Query: 309 GSAGKRRGTNGGA 321
++ + GG+
Sbjct: 464 DFPESQKSSRGGS 476
>gi|27477109 itchy homolog E3 ubiquitin protein ligase [Homo
sapiens]
Length = 862
Score = 41.2 bits (95), Expect = 0.002
Identities = 42/169 (24%), Positives = 65/169 (38%), Gaps = 23/169 (13%)
Query: 96 QPTRIIRGCTVTSPSRQSETQI-----TPAGGPAAFCDSTAESKRQLRVGAEGKGGGPQA 150
+PT I ++ Q E+++ T A+ D + SK + RV G A
Sbjct: 127 EPTETIGDLSICLDGLQLESEVVTNGETTCSESASQNDDGSRSKDETRVSTNGSDDPEDA 186
Query: 151 -LGRGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGEGRRAALGLEEAGPSL 209
G RRV+G P GF+P+R R RP P RR A S+
Sbjct: 187 GAGENRRVSGNNSPSLSNGGFKPSRPPRPSRP---------PPPTPRRPA--------SV 229
Query: 210 EGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCAGGKDKTP 258
G PS+ ++ SL ++ + T + + + T +GG P
Sbjct: 230 NGSPSATSESDGSSTGSLPPTNTNTNTSEGATSGLIIPLTISGGSGPRP 278
>gi|7706635 cornulin [Homo sapiens]
Length = 495
Score = 40.8 bits (94), Expect = 0.002
Identities = 42/172 (24%), Positives = 67/172 (38%), Gaps = 17/172 (9%)
Query: 109 PSRQSETQITPAGGPAAFCDSTAESKRQLRVGAE----GKGGGPQALGRGRRVNGPQGPD 164
P Q++ Q T + +++ D AES+ Q R+ + G+ Q G G+R +
Sbjct: 150 PGVQTQGQATGSAWVSSY-DRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTE--- 205
Query: 165 RWPNGFRPARQRRTRRPARALNSGQWSPGEGRRAALG----LEEAGPSLEGIPSSEWDTF 220
RP RQ +TR RA +G+ G G + G +E+ G S +
Sbjct: 206 -----MRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEA 260
Query: 221 SRDKRSLLSSHGSPGTIQSSVDIPSLTNTCAGGKDKTPPFSQEVDDPHALSS 272
+ D+ +HG + S AG +TP + E D H S
Sbjct: 261 TNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGS 312
>gi|113413437 PREDICTED: hypothetical protein [Homo sapiens]
Length = 324
Score = 38.9 bits (89), Expect = 0.009
Identities = 79/283 (27%), Positives = 101/283 (35%), Gaps = 53/283 (18%)
Query: 61 GAAAPTKSALQVQVVPSSQAVEFGQHPGRGLQDRTQPTRIIRGCTVTSPSRQSETQITPA 120
GAA PT S PSSQ+ H L + P + R C + E ++
Sbjct: 52 GAALPTSS-------PSSQSRRLPSH----LTTTSPPWDLFR-CWFYRTVTKKEGKLLHL 99
Query: 121 G-------GPAAFCDST-AESKRQLRVGAEGKGG-GPQALGRGRRVNGPQGPDRWPNGFR 171
G PA DS A L GA KG GP+ G G + GP P R
Sbjct: 100 GTAPETLPDPAPLTDSLLAAPYIFLSAGAVQKGDFGPK--GIGMKGGGPGLPPRG-KASG 156
Query: 172 PAR------QRRTRRPARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKR 225
PAR +R TRRP R G PG + A + GP G P S +R
Sbjct: 157 PARDSAQQRRRPTRRP-RGTRGGARRPGVRGQGAAAVGPTGPRPTGAPPSRRTPPPGPRR 215
Query: 226 SLLSSHGSPGTIQSSVDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLE 285
L S H G + P AG + P + P L+ F + L + + E
Sbjct: 216 PLRSPHSGSGWTPARPPSPP-----AGAPEALRPPASTTRAPAPLTLSFSARGL-AWAGE 269
Query: 286 LPA------------RLPTRCLPSPPRSLVAPSESGSAGKRRG 316
PA +L RC SP + ES S +RG
Sbjct: 270 SPASHQSERRWQWTRKLGCRCYCSP----LGSGESLSLSSKRG 308
>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein
[Homo sapiens]
Length = 1736
Score = 38.9 bits (89), Expect = 0.009
Identities = 73/316 (23%), Positives = 99/316 (31%), Gaps = 66/316 (20%)
Query: 112 QSETQITPA-GGPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGF 170
+ ET++ PA A + A R G +G+ G P L G V GP GP
Sbjct: 355 REETELGPALSAETAHSGAAAHGPR----GLKGEKGEPAVLEPGMLVEGPPGP------- 403
Query: 171 RPARQRRTRRPARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSR---DKRSL 227
EG +G P ++G P D R + L
Sbjct: 404 -----------------------EGPAGLIG----PPGIQGNPGPVGDPGERGPPGRAGL 436
Query: 228 LSSHGSPGTIQSSVDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELP 287
S G+PG +S+ +P +GG DK P + + A+
Sbjct: 437 PGSDGAPGPPGTSLMLPFRFG--SGGGDKGPVVAAQEAQAQAILQ--------------Q 480
Query: 288 ARLPTRCLPSPPRSLVAPSESGSAGK--RRGTNGGATPRKSCDASGAWGGKAKAHGWAPL 345
ARL R P P P G G +G +G P+ G G KA
Sbjct: 481 ARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRA 540
Query: 346 TAFLRRLHSALVGVKGGAGGAALTSLRAVPAREGGAGSRSEPREAARGQEPPLRHCRACL 405
A R GVKG G L L G G++ P E R
Sbjct: 541 GADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGE------RGDD 594
Query: 406 PQLSAMRSPGQGRPEG 421
++ PG+ P G
Sbjct: 595 GEIGPRGLPGESGPRG 610
Score = 31.2 bits (69), Expect = 1.9
Identities = 63/259 (24%), Positives = 86/259 (33%), Gaps = 36/259 (13%)
Query: 140 GAEGKGGG--PQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGE-GR 196
GA+G GG P R + GPQGP+ +P P P G PG G+
Sbjct: 859 GAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP--------PGPPGKDG--LPGHPGQ 908
Query: 197 RAALGLE-----EAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCA 251
R +G + P + G + +T +R G PG +P
Sbjct: 909 RGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPG----EQGLPGTAGKEG 964
Query: 252 GGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPS-PPRSLVAPSESGS 310
D PP + D P L FP + G L PS PP +P E G+
Sbjct: 965 TKGDPGPPGAPGKDGPAGLRG--FPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGA 1022
Query: 311 AGKRR--GTNGGATPRKSCDASGAWGGKAKAHGWAPLTAFLRRLHSALVGVKGGAGGAAL 368
AG G G P+ A+G G + P + GV+G G
Sbjct: 1023 AGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP---------TGRDGVQGPVGLPGP 1073
Query: 369 TSLRAVPAREGGAGSRSEP 387
V +G G +P
Sbjct: 1074 AGPPGVAGEDGDKGEVGDP 1092
>gi|169164483 PREDICTED: hypothetical protein [Homo sapiens]
Length = 324
Score = 38.5 bits (88), Expect = 0.012
Identities = 41/127 (32%), Positives = 53/127 (41%), Gaps = 11/127 (8%)
Query: 120 AGGPAAFCDSTAESKRQLRVGAEGKGGG--PQALGRGRRVNGPQGPDRWPNGFRPARQR- 176
A GPA DS + +R R +GG P G+G GP GP P G P+R+
Sbjct: 154 ASGPAR--DSAQQRRRPTRRPRGTRGGARRPGVRGQGAAAVGPTGPR--PTGAPPSRRTP 209
Query: 177 --RTRRPARALNSGQ-WSPGEGRRAALGLEEA-GPSLEGIPSSEWDTFSRDKRSLLSSHG 232
RRP R+ +SG W+P G EA P + T S R L +
Sbjct: 210 PPGPRRPLRSPHSGSGWTPARPPSPPAGAPEALRPPASTTRAPAPLTLSFSARGLAWAGE 269
Query: 233 SPGTIQS 239
SP + QS
Sbjct: 270 SPASHQS 276
Score = 38.1 bits (87), Expect = 0.015
Identities = 52/185 (28%), Positives = 67/185 (36%), Gaps = 30/185 (16%)
Query: 144 KGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGEGRRAALGLE 203
KGGGP RG+ GP R R+R TRRP R G PG + A +
Sbjct: 142 KGGGPGLPPRGKA----SGPAR---DSAQQRRRPTRRP-RGTRGGARRPGVRGQGAAAVG 193
Query: 204 EAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCAGGKDKTPPFSQE 263
GP G P S +R L S H G + P AG + P +
Sbjct: 194 PTGPRPTGAPPSRRTPPPGPRRPLRSPHSGSGWTPARPPSPP-----AGAPEALRPPAST 248
Query: 264 VDDPHALSSPFFPKQLGSLSLELPA------------RLPTRCLPSPPRSLVAPSESGSA 311
P L+ F + L + + E PA +L RC SP + ES S
Sbjct: 249 TRAPAPLTLSFSARGL-AWAGESPASHQSERRWQWTRKLGCRCYCSP----LGSGESLSL 303
Query: 312 GKRRG 316
+RG
Sbjct: 304 SSKRG 308
>gi|113414226 PREDICTED: hypothetical protein [Homo sapiens]
Length = 324
Score = 38.5 bits (88), Expect = 0.012
Identities = 41/127 (32%), Positives = 53/127 (41%), Gaps = 11/127 (8%)
Query: 120 AGGPAAFCDSTAESKRQLRVGAEGKGGG--PQALGRGRRVNGPQGPDRWPNGFRPARQR- 176
A GPA DS + +R R +GG P G+G GP GP P G P+R+
Sbjct: 154 ASGPAR--DSAQQRRRPTRRPRGTRGGARRPGVRGQGAAAVGPTGPR--PTGAPPSRRTP 209
Query: 177 --RTRRPARALNSGQ-WSPGEGRRAALGLEEA-GPSLEGIPSSEWDTFSRDKRSLLSSHG 232
RRP R+ +SG W+P G EA P + T S R L +
Sbjct: 210 PPGPRRPLRSPHSGSGWTPARPPSPPAGAPEALRPPASTTRAPAPLTLSFSARGLAWAGE 269
Query: 233 SPGTIQS 239
SP + QS
Sbjct: 270 SPASHQS 276
Score = 38.1 bits (87), Expect = 0.015
Identities = 52/185 (28%), Positives = 67/185 (36%), Gaps = 30/185 (16%)
Query: 144 KGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGEGRRAALGLE 203
KGGGP RG+ GP R R+R TRRP R G PG + A +
Sbjct: 142 KGGGPGLPPRGKA----SGPAR---DSAQQRRRPTRRP-RGTRGGARRPGVRGQGAAAVG 193
Query: 204 EAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCAGGKDKTPPFSQE 263
GP G P S +R L S H G + P AG + P +
Sbjct: 194 PTGPRPTGAPPSRRTPPPGPRRPLRSPHSGSGWTPARPPSPP-----AGAPEALRPPAST 248
Query: 264 VDDPHALSSPFFPKQLGSLSLELPA------------RLPTRCLPSPPRSLVAPSESGSA 311
P L+ F + L + + E PA +L RC SP + ES S
Sbjct: 249 TRAPAPLTLSFSARGL-AWAGESPASHQSERRWQWTRKLGCRCYCSP----LGSGESLSL 303
Query: 312 GKRRG 316
+RG
Sbjct: 304 SSKRG 308
>gi|110227615 echinoderm microtubule associated protein like 3 [Homo
sapiens]
Length = 896
Score = 37.7 bits (86), Expect = 0.020
Identities = 52/189 (27%), Positives = 76/189 (40%), Gaps = 12/189 (6%)
Query: 62 AAAPTKSALQVQVVPSS-QAVEFGQHPGRGLQDRTQPTRIIRGCTVTSPSR--QSETQIT 118
A A L++QV PSS Q PG L P + CT + SR Q+ET++
Sbjct: 36 ALAEALRLLRLQVPPSSLQGSGTPAPPGDSL---AAPPGLPPTCTPSLVSRGTQTETEVE 92
Query: 119 PAGGPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRT 178
P S Q GA + G Q+ G G +G P P RP + +
Sbjct: 93 LKSSPGPPGLSNGPPAPQ---GASEEPSGTQSEGGGSSSSGAGSPGP-PGILRPLQPPQR 148
Query: 179 RRPARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQ 238
R +S SP E R L + + + S T SR + LSS G PG+ +
Sbjct: 149 ADTPRRNSSSSSSPSERPRQKLSRKAISSANLLVRSGS--TESRGGKDPLSSPGGPGSRR 206
Query: 239 SSVDIPSLT 247
S+ ++ ++
Sbjct: 207 SNYNLEGIS 215
>gi|169160983 PREDICTED: hypothetical protein [Homo sapiens]
Length = 261
Score = 37.4 bits (85), Expect = 0.026
Identities = 41/121 (33%), Positives = 54/121 (44%), Gaps = 19/121 (15%)
Query: 297 SPPRSLVAPSESGSAGKR-----RGTNGGATPRKSCDASGAWGGKAKAHGWAPLTAFLRR 351
S R+ P E G+ G+R RG +GG G+ GG +A + L RR
Sbjct: 104 SRQRTADFPREEGALGRRLRPSPRGKSGG----------GSRGGSRRALVLSSLQDPPRR 153
Query: 352 LHSALVGVKGGAGGAALTSLRAVPAREGGAGSRSEPREAARGQEPPLRHCRACLPQLSAM 411
H L + G+G AA T LR R AG+R P + AR +E P R LP L +
Sbjct: 154 GHRCLRERRRGSGVAAGTLLRG-RGRRREAGTR-RPAQGARSEEDP--GARRLLPGLRSR 209
Query: 412 R 412
R
Sbjct: 210 R 210
>gi|13994190 frizzled 8 [Homo sapiens]
Length = 694
Score = 37.4 bits (85), Expect = 0.026
Identities = 38/133 (28%), Positives = 46/133 (34%), Gaps = 36/133 (27%)
Query: 292 TRCLPSPPRSLVAP--SESGSAGKRRGTNGGATPRKSCDASGAWGGKAKAHGWAPLTAFL 349
T PSPPR L P E +G G GA P
Sbjct: 157 TTAAPSPPRRLPPPPPGEQPPSGSGHGRPPGARPP------------------------- 191
Query: 350 RRLHSALVGVKGGAGGAALTSLRAVPAREGGAGSRSEPREAARGQEPPLRHCRACLPQLS 409
H G +GG GG A A PAR GG G ++ P P CRA + +S
Sbjct: 192 ---HRG--GGRGGGGGDAA----APPARGGGGGGKARPPGGGAAPCEPGCQCRAPMVSVS 242
Query: 410 AMRSPGQGRPEGG 422
+ R P R + G
Sbjct: 243 SERHPLYNRVKTG 255
>gi|59806361 hypothetical protein LOC387104 [Homo sapiens]
Length = 947
Score = 37.0 bits (84), Expect = 0.034
Identities = 54/231 (23%), Positives = 80/231 (34%), Gaps = 35/231 (15%)
Query: 174 RQRRTRRPARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHGS 233
+Q+R + PAR +S R+ +G AG L + + + S G
Sbjct: 35 KQQRAQSPARPRDSSLRQTIAATRSPVG---AGTKLNSVRQQQLQQQQQQGNKTGSRTGP 91
Query: 234 PGTIQSSVDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLEL------- 286
P +I+ GG +K P + + P A+ + + +L
Sbjct: 92 PASIRGG----------GGGAEKATPLAPKGAAPGAVQPVAGAEAAPAATLAALGGRRPG 141
Query: 287 PARLPTRCLPSPPRSLVAPSESGSAGKRRGTNGGATPRKSCDASGAWGGKAKAHGWAPLT 346
P P R L S P L P G G G G GA GG + G AP
Sbjct: 142 PPEEPPRELESVPSKLGEPPPLGEGGGGGGEGG-----------GAGGGSGEREGGAPQP 190
Query: 347 AFLR--RLHSALVGVKGGAG--GAALTSLRAVPAREGGAGSRSEPREAARG 393
R R +GG+G GA+ + + + G GSR+ A G
Sbjct: 191 PPPRGWRGKGVRAQQRGGSGGEGASPSPSSSSAGKTPGTGSRNSGSGVAGG 241
>gi|239756562 PREDICTED: hypothetical protein [Homo sapiens]
Length = 235
Score = 36.6 bits (83), Expect = 0.044
Identities = 31/104 (29%), Positives = 39/104 (37%), Gaps = 5/104 (4%)
Query: 289 RLPTRCLPSPPRSLVAPSESGSAGKRRGTNGGATPRKSCDASGAWGGKAKAHGWAPLTAF 348
R +R S P+S + S KRRG GG PR+ A+ AK+ G
Sbjct: 125 RAGSRVCRSRPQSRGGQKAAASGAKRRGV-GGKEPRRQKPAAAG----AKSRGGKSHKKP 179
Query: 349 LRRLHSALVGVKGGAGGAALTSLRAVPAREGGAGSRSEPREAAR 392
RR A G GG A A+ G G +PR R
Sbjct: 180 RRRGQKAAPAKNSGGGGNKPQKAAAAGAKNRGGGGGKKPRRGRR 223
>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein
[Homo sapiens]
Length = 1650
Score = 36.6 bits (83), Expect = 0.044
Identities = 66/287 (22%), Positives = 88/287 (30%), Gaps = 61/287 (21%)
Query: 140 GAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGEGRRAA 199
G +G+ G P L G V GP GP EG
Sbjct: 294 GLKGEKGEPAVLEPGMLVEGPPGP------------------------------EGPAGL 323
Query: 200 LGLEEAGPSLEGIPSSEWDTFSR---DKRSLLSSHGSPGTIQSSVDIPSLTNTCAGGKDK 256
+G P ++G P D R + L S G+PG +S+ +P +GG DK
Sbjct: 324 IG----PPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFG--SGGGDK 377
Query: 257 TPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPRSLVAPSESGSAGK--R 314
P + + A+ ARL R P P P G G
Sbjct: 378 GPVVAAQEAQAQAILQ--------------QARLALRGPPGPMGYTGRPGPLGQPGSPGL 423
Query: 315 RGTNGGATPRKSCDASGAWGGKAKAHGWAPLTAFLRRLHSALVGVKGGAGGAALTSLRAV 374
+G +G P+ G G KA A R GVKG G L L
Sbjct: 424 KGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGE 483
Query: 375 PAREGGAGSRSEPREAARGQEPPLRHCRACLPQLSAMRSPGQGRPEG 421
G G++ P E R ++ PG+ P G
Sbjct: 484 KGHRGDTGAQGLPGPPGEDGE------RGDDGEIGPRGLPGESGPRG 524
Score = 31.2 bits (69), Expect = 1.9
Identities = 63/259 (24%), Positives = 86/259 (33%), Gaps = 36/259 (13%)
Query: 140 GAEGKGGG--PQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGE-GR 196
GA+G GG P R + GPQGP+ +P P P G PG G+
Sbjct: 773 GAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP--------PGPPGKDG--LPGHPGQ 822
Query: 197 RAALGLE-----EAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCA 251
R +G + P + G + +T +R G PG +P
Sbjct: 823 RGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPG----EQGLPGTAGKEG 878
Query: 252 GGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPS-PPRSLVAPSESGS 310
D PP + D P L FP + G L PS PP +P E G+
Sbjct: 879 TKGDPGPPGAPGKDGPAGLRG--FPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGA 936
Query: 311 AGKRR--GTNGGATPRKSCDASGAWGGKAKAHGWAPLTAFLRRLHSALVGVKGGAGGAAL 368
AG G G P+ A+G G + P + GV+G G
Sbjct: 937 AGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP---------TGRDGVQGPVGLPGP 987
Query: 369 TSLRAVPAREGGAGSRSEP 387
V +G G +P
Sbjct: 988 AGPPGVAGEDGDKGEVGDP 1006
>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein
[Homo sapiens]
Length = 1629
Score = 36.6 bits (83), Expect = 0.044
Identities = 66/287 (22%), Positives = 88/287 (30%), Gaps = 61/287 (21%)
Query: 140 GAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGEGRRAA 199
G +G+ G P L G V GP GP EG
Sbjct: 273 GLKGEKGEPAVLEPGMLVEGPPGP------------------------------EGPAGL 302
Query: 200 LGLEEAGPSLEGIPSSEWDTFSR---DKRSLLSSHGSPGTIQSSVDIPSLTNTCAGGKDK 256
+G P ++G P D R + L S G+PG +S+ +P +GG DK
Sbjct: 303 IG----PPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFG--SGGGDK 356
Query: 257 TPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPRSLVAPSESGSAGK--R 314
P + + A+ ARL R P P P G G
Sbjct: 357 GPVVAAQEAQAQAILQ--------------QARLALRGPPGPMGYTGRPGPLGQPGSPGL 402
Query: 315 RGTNGGATPRKSCDASGAWGGKAKAHGWAPLTAFLRRLHSALVGVKGGAGGAALTSLRAV 374
+G +G P+ G G KA A R GVKG G L L
Sbjct: 403 KGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGE 462
Query: 375 PAREGGAGSRSEPREAARGQEPPLRHCRACLPQLSAMRSPGQGRPEG 421
G G++ P E R ++ PG+ P G
Sbjct: 463 KGHRGDTGAQGLPGPPGEDGE------RGDDGEIGPRGLPGESGPRG 503
Score = 31.2 bits (69), Expect = 1.9
Identities = 63/259 (24%), Positives = 86/259 (33%), Gaps = 36/259 (13%)
Query: 140 GAEGKGGG--PQALGRGRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGE-GR 196
GA+G GG P R + GPQGP+ +P P P G PG G+
Sbjct: 752 GAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP--------PGPPGKDG--LPGHPGQ 801
Query: 197 RAALGLE-----EAGPSLEGIPSSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCA 251
R +G + P + G + +T +R G PG +P
Sbjct: 802 RGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPG----EQGLPGTAGKEG 857
Query: 252 GGKDKTPPFSQEVDDPHALSSPFFPKQLGSLSLELPARLPTRCLPS-PPRSLVAPSESGS 310
D PP + D P L FP + G L PS PP +P E G+
Sbjct: 858 TKGDPGPPGAPGKDGPAGLRG--FPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGA 915
Query: 311 AGKRR--GTNGGATPRKSCDASGAWGGKAKAHGWAPLTAFLRRLHSALVGVKGGAGGAAL 368
AG G G P+ A+G G + P + GV+G G
Sbjct: 916 AGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP---------TGRDGVQGPVGLPGP 966
Query: 369 TSLRAVPAREGGAGSRSEP 387
V +G G +P
Sbjct: 967 AGPPGVAGEDGDKGEVGDP 985
>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 673
Score = 36.2 bits (82), Expect = 0.058
Identities = 89/405 (21%), Positives = 137/405 (33%), Gaps = 55/405 (13%)
Query: 52 SSPTPIPEFGAAAPTKSALQVQVVPSSQAVEFGQHPGR----GLQDRTQPTRIIRGCTVT 107
+SPT P + + + ++PS+ + + P R G+ RT T++ ++T
Sbjct: 218 ASPTGTPPRASPTGSPPRASLSMMPSTALLI--RTPPRASPTGMLSRTSLTKMDSTASIT 275
Query: 108 -SPSRQSETQIT--PAGGPAAFCDSTAESKRQL-RVGAEGKGGGPQALGRGRRVNGPQGP 163
+PSR S T P+ + STA R L R G + + P
Sbjct: 276 RTPSRPSTASPTGTPSRASLSMTPSTASLMRMLPRASPTGMLSRTSLTKMDSTASISRTP 335
Query: 164 DRWPNGFRPARQRRTRRPARALNSGQWS----PGEGRRAALGLEEAGPSLEGIPSSEWDT 219
R P+R T +P+ A +G S G A+L + S G P T
Sbjct: 336 PRASITRTPSRASPTGKPSTASPTGTPSRASPTGSPSTASLTGLSSTASPTGTPPRASPT 395
Query: 220 FSRDKRSLLSS--HGSPGTIQSSVDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPK 277
+ SL SP + S I + +T + +TPP + P S
Sbjct: 396 GTPSTASLTRKPPRASPTGMLSRTSITKMDSTAS--PTRTPPRASPTGTPPRAS------ 447
Query: 278 QLGSLSLELPARLPTRCLPSPPRSLVAPSESGSAGKRRGTNGGATPRKSCDASGAWGGKA 337
P P+R P+ +S +P+ S S G+ A+P S + +
Sbjct: 448 ---------PTGTPSRASPTGTQSTASPTGSPSTASPTGSPSTASPTGSPSRASLTRTPS 498
Query: 338 KAH-------------------GWAPLTAFLRRLHSALVGVKGGAGGAALTSL--RAVPA 376
+A W P TA S + + G AALT RA
Sbjct: 499 RASLTKMESTASITRTPSRASPTWTPSTASPTGSPSTALAM-GSPSRAALTRTPSRASLT 557
Query: 377 REGGAGSRSEPREAARGQEPPLRHCRACLPQLSAMRSPGQGRPEG 421
R S + P A+ + P P S P + P G
Sbjct: 558 RTPSRASLTTPSRASLTRTPSTVLLTRMPPSASPTGMPSRTSPTG 602
>gi|239751535 PREDICTED: hypothetical protein [Homo sapiens]
Length = 255
Score = 36.2 bits (82), Expect = 0.058
Identities = 40/128 (31%), Positives = 49/128 (38%), Gaps = 15/128 (11%)
Query: 273 PFFPKQLGSLSLELPARLPTRCLPSPPRSLVAPSESG---SAGKRRGTNGGATPRKSCDA 329
P P+ S S RL R + P + P + S+ RG GGA+PR
Sbjct: 116 PRLPRPFTSASFSNQTRLRRRSASALPAPRLCPQRASPGCSSPGVRGPGGGASPR----- 170
Query: 330 SGAWGGKAKAHGWAPLTAFLRRLHSALVGVKGGAGGAALTSLRAVPAREGGAGSRSEPRE 389
A GG A A A A R SA V AG A + +P R GAG+R R
Sbjct: 171 --ARGGNAAAALAARQAAGGGRSRSAFV-----AGRDAALACAQLPRRPRGAGARRGMRR 223
Query: 390 AARGQEPP 397
E P
Sbjct: 224 RLGAGERP 231
>gi|239746046 PREDICTED: hypothetical protein XP_002343643 [Homo
sapiens]
Length = 255
Score = 36.2 bits (82), Expect = 0.058
Identities = 40/128 (31%), Positives = 49/128 (38%), Gaps = 15/128 (11%)
Query: 273 PFFPKQLGSLSLELPARLPTRCLPSPPRSLVAPSESG---SAGKRRGTNGGATPRKSCDA 329
P P+ S S RL R + P + P + S+ RG GGA+PR
Sbjct: 116 PRLPRPFTSASFSNQTRLRRRSASALPAPRLCPQRASPGCSSPGVRGPGGGASPR----- 170
Query: 330 SGAWGGKAKAHGWAPLTAFLRRLHSALVGVKGGAGGAALTSLRAVPAREGGAGSRSEPRE 389
A GG A A A A R SA V AG A + +P R GAG+R R
Sbjct: 171 --ARGGNAAAALAARQAAGGGRSRSAFV-----AGRDAALACAQLPRRPRGAGARRGMRR 223
Query: 390 AARGQEPP 397
E P
Sbjct: 224 RLGAGERP 231
>gi|87196343 PDZ domain containing 2 [Homo sapiens]
Length = 2839
Score = 35.8 bits (81), Expect = 0.075
Identities = 75/316 (23%), Positives = 105/316 (33%), Gaps = 53/316 (16%)
Query: 40 SWRSWRKDVAGCSSPTPIPEFGAAAPTKSALQVQVVPSSQAVEFGQHPGRGLQDRTQPTR 99
SW W+K+++G SS P E+ T+S PSS Q GL R +P
Sbjct: 1072 SW--WKKELSGSSS-APKLEYTVRTDTQSPTNTGS-PSSP-----QQKSEGLGSRHRPVA 1122
Query: 100 II-----RGCTVTSPSRQSETQITPAGGPAAFCDSTAESKR-QLRVGAEGKGGGPQALGR 153
+ R PS +T DS ++ ++ V GG +
Sbjct: 1123 RVSPHCKRSEAEAKPSGSQTVNLTGRANDPCDLDSRVQATSVKVTVAGFQPGGAVEKESL 1182
Query: 154 GRRVNGPQGPDRWPNGFRPARQRRTRRPARALNSGQWSPGEGRRAALGLEEAGPSLEGIP 213
G+ G A + A AL S + L +A L P
Sbjct: 1183 GKLTTGD------------ACVSTSCELASAL-----SHLDASHLTENLPKAASELGQQP 1225
Query: 214 SSEWDTFSRDKRSLLSSHGSPGTIQSSVDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSP 273
+E D+ S L+SS G G PS T+ G +V P S P
Sbjct: 1226 MTELDSSS----DLISSPGKKGAAHPD---PSKTSVDTG----------QVSRPENPSQP 1268
Query: 274 FFPKQLGSLSLELPARLPTRCLPSPPRSLVAPSESGSAGKRRGTNGGATPRKSCDASGAW 333
P+ + P RLP PSP AP + K R + +TP + +
Sbjct: 1269 ASPR-VTKCKARSPVRLPHEGSPSPGEKAAAPPD---YSKTRSASETSTPHNTRRVAALR 1324
Query: 334 GGKAKAHGWAPLTAFL 349
G A G P A L
Sbjct: 1325 GAGPGAEGMTPAGAVL 1340
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 35.4 bits (80), Expect = 0.098
Identities = 68/338 (20%), Positives = 116/338 (34%), Gaps = 37/338 (10%)
Query: 7 PQLRRGLTLLEARG-RRPGGKRGTEIRAVGEQLESWRSWRKDVA----------GCSSPT 55
P+ R A+G RRPG + ++ E + S +S + A G P
Sbjct: 2437 PKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPK 2496
Query: 56 PIPEFGAAAPTKSALQVQVV-PSSQAVEFGQHPGRGL--QDRTQPTRIIRGCTVTSPSRQ 112
+ G+ P + + + P + + Q PG GL +D P + + +
Sbjct: 2497 SLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEE 2556
Query: 113 SETQITPAGGPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRP 172
SE+ + + G ++ S++ S + EG G G G R
Sbjct: 2557 SESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCS------------- 2603
Query: 173 ARQRRTRRPARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEWDTFSRDKRSLLSSHG 232
A R PA + +S S ++ + S SS + S S SS
Sbjct: 2604 AASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS--SSSS 2661
Query: 233 SPGTIQSSVDIPSLTNTCAGGKDKTPPFSQEVDDPHALSSPFFPKQLG-------SLSLE 285
S + SS ++C+ + P + AL + KQ G S +
Sbjct: 2662 SSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTK-ATKQAGKARPSAHSPGKK 2720
Query: 286 LPARLPTRCLPSPPRSLVAPSESGSAGKRRGTNGGATP 323
PA P P P + L +++G+ + + G P
Sbjct: 2721 TPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVHLP 2758
>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
Length = 819
Score = 35.0 bits (79), Expect = 0.13
Identities = 51/219 (23%), Positives = 80/219 (36%), Gaps = 25/219 (11%)
Query: 12 GLTLLEARGRRPGGKRGTEIRAVGEQLESWRSWRKDVAG----------CSSPTPIPEFG 61
G L RGR+P +RG + A G + WR+ + AG ++ + G
Sbjct: 112 GTKSLGGRGRKPR-RRGQKAAATGSKKPRWRAQKSAAAGSKNRGAGAQKAAAAAGVKSQG 170
Query: 62 AAAPTKSALQVQVVPSSQAVEFGQHPGRGLQDRTQPTRIIR---GCTVTSPSRQSETQIT 118
P K+A S + RG +D+ R + G T ++
Sbjct: 171 GEKPQKAAAAGAKSRSGKKPRRRGAKSRGDEDKKGRQREAKSRFGKTRGGRRKKHRRPKP 230
Query: 119 PAGGPAAFCDSTAESKRQLRVGAEGKGGGPQALGRGRRVNGPQGPDRWPNGFRPARQRRT 178
AGG + + ++Q R G + GG +G+ R G D+ + RQ +
Sbjct: 231 AAGGAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSR-----GGGDK-----KLRRQGQN 280
Query: 179 RRPARALNSGQWSPGEGRRAALGLEEAGPSLEGIPSSEW 217
A A G + GE + AA G GP G + W
Sbjct: 281 AALAGAKRRGAATAGE-KPAAKGRGGRGPKSLGGQNPRW 318
>gi|239753839 PREDICTED: hypothetical protein [Homo sapiens]
Length = 257
Score = 35.0 bits (79), Expect = 0.13
Identities = 43/142 (30%), Positives = 53/142 (37%), Gaps = 12/142 (8%)
Query: 283 SLELPARLPTRCLPSPPRSLVAPSESGSAGKRRGTNGGATPRKSCDASGAWGGKAKAHGW 342
S E P C P+ + P+ + A RR G A P C A G A
Sbjct: 65 SQEHPGAGGPLCFPARSAAWGPPARASRAAGRRA--GPAGP--PCRAPGRGRAAATRRSP 120
Query: 343 APLTAFLRRLHSALVGVKGGAGGAALTSLRAVPARE-----GGAGSRSEPREAARGQEPP 397
AP TA R A V GGA A+ R+VPAR GG + R R
Sbjct: 121 APGTA---RGSPAGVERAGGATAASSAGTRSVPARRLPPPCGGTSLGAGSRALRRPGSAA 177
Query: 398 LRHCRACLPQLSAMRSPGQGRP 419
L + + +AM PG RP
Sbjct: 178 LPRSPSSSRRWAAMPGPGAPRP 199
>gi|93141049 collagen, type XII, alpha 1 short isoform precursor [Homo
sapiens]
Length = 1899
Score = 35.0 bits (79), Expect = 0.13
Identities = 39/138 (28%), Positives = 49/138 (35%), Gaps = 22/138 (15%)
Query: 255 DKTPPFSQEVDDPHALSSPFFPKQLGSLSLE-------LPARLPTRCLPSPPRSLVAPSE 307
D PP Q P + P + G ++ LP R T LP PP + P +
Sbjct: 1617 DIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGD 1676
Query: 308 SGSAGK--RRGTNGGATPRKSCDASGAWG-----GKAKAHGWAPLTAFLRRLHSALVGVK 360
G GK G G P S + G G GK HG R S L G K
Sbjct: 1677 RGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHG--------RPGPSGLKGEK 1728
Query: 361 GGAGGAALTSLRAVPARE 378
G G A ++ AR+
Sbjct: 1729 GDRGDIASQNMMRAVARQ 1746
>gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo
sapiens]
Length = 3063
Score = 35.0 bits (79), Expect = 0.13
Identities = 39/138 (28%), Positives = 49/138 (35%), Gaps = 22/138 (15%)
Query: 255 DKTPPFSQEVDDPHALSSPFFPKQLGSLSLE-------LPARLPTRCLPSPPRSLVAPSE 307
D PP Q P + P + G ++ LP R T LP PP + P +
Sbjct: 2781 DIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGD 2840
Query: 308 SGSAGK--RRGTNGGATPRKSCDASGAWG-----GKAKAHGWAPLTAFLRRLHSALVGVK 360
G GK G G P S + G G GK HG R S L G K
Sbjct: 2841 RGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHG--------RPGPSGLKGEK 2892
Query: 361 GGAGGAALTSLRAVPARE 378
G G A ++ AR+
Sbjct: 2893 GDRGDIASQNMMRAVARQ 2910
>gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens]
Length = 1142
Score = 35.0 bits (79), Expect = 0.13
Identities = 48/183 (26%), Positives = 63/183 (34%), Gaps = 24/183 (13%)
Query: 207 PSLEGIPSSEWDTFSRDKRSLLSSHGSPGTI-QSSVDIPSLTNTCAGGKDKTPPFSQEVD 265
P L+G P + + +R L HGSPG I + IP T A G P
Sbjct: 590 PGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTG--AQGPAGEPGIQGPRG 647
Query: 266 DPHALSSPFFPKQLGSLSLELPARLPTRCLPSPPRSLVAPSESGSAGKRRGTNGGATPRK 325
P +P P G +P R LP PP +A G G G
Sbjct: 648 LPGLPGTPGTPGNDG-----VPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCG----- 697
Query: 326 SCDAS--GAWGGKAKAHGWAPLTAFLRRLHSALVGVKGGAGGAALTSLRAVPAREGGAGS 383
+C AS G K + G + +G +G G +P REG GS
Sbjct: 698 NCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPG---------IPGREGPKGS 748
Query: 384 RSE 386
+ E
Sbjct: 749 KGE 751
>gi|169207782 PREDICTED: hypothetical protein [Homo sapiens]
Length = 330
Score = 34.7 bits (78), Expect = 0.17
Identities = 38/125 (30%), Positives = 46/125 (36%), Gaps = 25/125 (20%)
Query: 296 PSPPRSLVAPSESGSAGKRRGTNGGATPRKSCDASGAWGGKAKAHGWAPLTAFLRRLHSA 355
P P SLV P GS R G R C S G + + +P +
Sbjct: 105 PGPAGSLVFPERRGSLQDRLGR----ASRPGCPPSPR-GSRQERGANSPGRS-------- 151
Query: 356 LVGVKGGAGGAALTSLRAVPAREGGAGSRSEPREAARGQEPPLRHCRACL--PQLSAMRS 413
G +G G AAL ++ R PR ARG +PP R A L P R
Sbjct: 152 --GARGCGGAAAL--------QQEPTNFRGRPRPGARGTDPPGRTLPAPLARPSTQPGRR 201
Query: 414 PGQGR 418
PG GR
Sbjct: 202 PGLGR 206
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,176,482
Number of Sequences: 37866
Number of extensions: 1240185
Number of successful extensions: 4676
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 268
Number of HSP's that attempted gapping in prelim test: 4427
Number of HSP's gapped (non-prelim): 554
length of query: 422
length of database: 18,247,518
effective HSP length: 105
effective length of query: 317
effective length of database: 14,271,588
effective search space: 4524093396
effective search space used: 4524093396
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.