Guide to the Human Genome
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Search of human proteins with 239755571

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239755571 PREDICTED: hypothetical protein [Homo sapiens]
         (261 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239755571 PREDICTED: hypothetical protein [Homo sapiens]           540   e-154
gi|239744417 PREDICTED: similar to hCG2023245 [Homo sapiens]          509   e-145
gi|239742114 PREDICTED: similar to hCG2023245 [Homo sapiens]          331   3e-91
gi|239744552 PREDICTED: hypothetical protein [Homo sapiens]           241   5e-64
gi|239749365 PREDICTED: hypothetical protein XP_002347014 [Homo ...   114   9e-26
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    55   5e-08
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    55   5e-08
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      55   8e-08
gi|91208420 bassoon protein [Homo sapiens]                             50   2e-06
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    50   2e-06
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      49   3e-06
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       49   4e-06
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]        48   8e-06
gi|11415052 retinoid X receptor, beta [Homo sapiens]                   47   2e-05
gi|239753839 PREDICTED: hypothetical protein [Homo sapiens]            47   2e-05
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    47   2e-05
gi|19913396 smoothelin isoform b [Homo sapiens]                        47   2e-05
gi|19913394 smoothelin isoform c [Homo sapiens]                        47   2e-05
gi|19913398 smoothelin isoform a [Homo sapiens]                        47   2e-05
gi|169204930 PREDICTED: hypothetical protein [Homo sapiens]            47   2e-05
gi|239750393 PREDICTED: hypothetical protein [Homo sapiens]            47   2e-05
gi|239744694 PREDICTED: hypothetical protein [Homo sapiens]            47   2e-05
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...    46   3e-05
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    46   3e-05
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    46   3e-05
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             46   3e-05
gi|48255931 hepatoma-derived growth factor-related protein 2 iso...    46   3e-05
gi|14249158 hepatoma-derived growth factor-related protein 2 iso...    46   3e-05
gi|239754081 PREDICTED: hypothetical protein XP_002345876 [Homo ...    46   4e-05
gi|239749251 PREDICTED: similar to hCG2042508 [Homo sapiens]           46   4e-05

>gi|239755571 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 261

 Score =  540 bits (1390), Expect = e-154
 Identities = 261/261 (100%), Positives = 261/261 (100%)

Query: 1   MSTLSGRPFSPPWAGRPSGCNLVGAGRRCRAWPERAWPQAGDSDCLGQGRRAQRRPGPGV 60
           MSTLSGRPFSPPWAGRPSGCNLVGAGRRCRAWPERAWPQAGDSDCLGQGRRAQRRPGPGV
Sbjct: 1   MSTLSGRPFSPPWAGRPSGCNLVGAGRRCRAWPERAWPQAGDSDCLGQGRRAQRRPGPGV 60

Query: 61  SAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPSSSPGA 120
           SAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPSSSPGA
Sbjct: 61  SAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPSSSPGA 120

Query: 121 GRAPGAMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQPDDGEDAPR 180
           GRAPGAMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQPDDGEDAPR
Sbjct: 121 GRAPGAMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQPDDGEDAPR 180

Query: 181 PGRKETGTQTGGDGRGVSDAGAGVRGCRGCRGRGVGAAGGSVAGPGLKLVTERQLRRARS 240
           PGRKETGTQTGGDGRGVSDAGAGVRGCRGCRGRGVGAAGGSVAGPGLKLVTERQLRRARS
Sbjct: 181 PGRKETGTQTGGDGRGVSDAGAGVRGCRGCRGRGVGAAGGSVAGPGLKLVTERQLRRARS 240

Query: 241 DSSRRPPRRQLPLLGCVASTS 261
           DSSRRPPRRQLPLLGCVASTS
Sbjct: 241 DSSRRPPRRQLPLLGCVASTS 261


>gi|239744417 PREDICTED: similar to hCG2023245 [Homo sapiens]
          Length = 364

 Score =  509 bits (1311), Expect = e-145
 Identities = 247/247 (100%), Positives = 247/247 (100%)

Query: 15  GRPSGCNLVGAGRRCRAWPERAWPQAGDSDCLGQGRRAQRRPGPGVSAVGASGQQRAPES 74
           GRPSGCNLVGAGRRCRAWPERAWPQAGDSDCLGQGRRAQRRPGPGVSAVGASGQQRAPES
Sbjct: 118 GRPSGCNLVGAGRRCRAWPERAWPQAGDSDCLGQGRRAQRRPGPGVSAVGASGQQRAPES 177

Query: 75  NERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPSSSPGAGRAPGAMASPSGSS 134
           NERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPSSSPGAGRAPGAMASPSGSS
Sbjct: 178 NERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPSSSPGAGRAPGAMASPSGSS 237

Query: 135 KATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQPDDGEDAPRPGRKETGTQTGGDG 194
           KATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQPDDGEDAPRPGRKETGTQTGGDG
Sbjct: 238 KATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQPDDGEDAPRPGRKETGTQTGGDG 297

Query: 195 RGVSDAGAGVRGCRGCRGRGVGAAGGSVAGPGLKLVTERQLRRARSDSSRRPPRRQLPLL 254
           RGVSDAGAGVRGCRGCRGRGVGAAGGSVAGPGLKLVTERQLRRARSDSSRRPPRRQLPLL
Sbjct: 298 RGVSDAGAGVRGCRGCRGRGVGAAGGSVAGPGLKLVTERQLRRARSDSSRRPPRRQLPLL 357

Query: 255 GCVASTS 261
           GCVASTS
Sbjct: 358 GCVASTS 364


>gi|239742114 PREDICTED: similar to hCG2023245 [Homo sapiens]
          Length = 329

 Score =  331 bits (849), Expect = 3e-91
 Identities = 170/193 (88%), Positives = 174/193 (90%), Gaps = 6/193 (3%)

Query: 54  RRPGPGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPG 113
           RRPGPGVSAV A GQQRAPES ERPAEE  PA MPSSAPRGPTEPA RRPSSADRPLAPG
Sbjct: 86  RRPGPGVSAVSAGGQQRAPESQERPAEESAPALMPSSAPRGPTEPAFRRPSSADRPLAPG 145

Query: 114 PSSSPGAGRAPGAMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQP- 172
           PSSSPGAGRAP AMASPSGSS+ATGKPRGRDG PRREEDDV PEEKRLRLLLE GSAQP 
Sbjct: 146 PSSSPGAGRAPRAMASPSGSSEATGKPRGRDGGPRREEDDVPPEEKRLRLLLERGSAQPE 205

Query: 173 --DDGEDAPRPGRKETGTQTGGDGRGVSDAGAGVRGCRGCRGRGVGAAGGSVAGPGLKLV 230
             +DGEDAPRPGRK+TGTQTGGDGRGVSD GAGV   RGC+GRGVGAAGGSVAGPGLKLV
Sbjct: 206 DCEDGEDAPRPGRKKTGTQTGGDGRGVSDVGAGV---RGCQGRGVGAAGGSVAGPGLKLV 262

Query: 231 TERQLRRARSDSS 243
            ERQLRRARSDSS
Sbjct: 263 IERQLRRARSDSS 275


>gi|239744552 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 221

 Score =  241 bits (615), Expect = 5e-64
 Identities = 140/221 (63%), Positives = 151/221 (68%), Gaps = 22/221 (9%)

Query: 1   MSTLSGRPFSPPWAGRPSGCNLVGAGRRCRAWPERAWPQAGDSDCLGQGRRAQRRPGPGV 60
           MSTLSGRPFS     R +    +G          +   +AG    L  G+  QR PGPG 
Sbjct: 1   MSTLSGRPFSSSSLSRET----IGVQPGWGGEEVQGLARAG----LATGK-GQRPPGPGR 51

Query: 61  SAVGASGQQRAPESNERPAEEPT----------PAPMPSSAPRGPTEPALRRPSSADRPL 110
                +  +R   + ERPAE              APMPSSAPRGPTEPALRRPSSA+RPL
Sbjct: 52  VRAAQARARRGGGARERPAEGARGPRAARGGARAAPMPSSAPRGPTEPALRRPSSAERPL 111

Query: 111 APGPSSSPGAGRAPGAMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSA 170
           A  PSSS   GRAPGAMASPS SS+ATGKPRGRDGRPRREEDDV PEEKRLRLLLE GSA
Sbjct: 112 AQAPSSSASVGRAPGAMASPSRSSEATGKPRGRDGRPRREEDDVPPEEKRLRLLLEGGSA 171

Query: 171 QP---DDGEDAPRPGRKETGTQTGGDGRGVSDAGAGVRGCR 208
           QP   +DGEDAPRPGR ETGTQTGGDGRGVSDAGAGVRGCR
Sbjct: 172 QPQDGEDGEDAPRPGRVETGTQTGGDGRGVSDAGAGVRGCR 212


>gi|239749365 PREDICTED: hypothetical protein XP_002347014 [Homo
           sapiens]
          Length = 190

 Score =  114 bits (285), Expect = 9e-26
 Identities = 80/196 (40%), Positives = 94/196 (47%), Gaps = 29/196 (14%)

Query: 1   MSTLSGRPFSPPWAGRPSGCNLVGAGRRCRAWPERAWPQAGDSDCLGQGRRAQRRPGPGV 60
           MSTLSGRPFS     +         GR   A P ++ P  G        R  +   GP  
Sbjct: 1   MSTLSGRPFSSLLLRQGDYRGATWLGRGGGAGPGQSGPGHGQGTATSWARTGESGAGPSP 60

Query: 61  SAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPSSSPGA 120
           +    +G+  A    +R    P  +P              RRP +  R           A
Sbjct: 61  AWRRCAGE--ASRGRQRARSGPPKSP--------------RRPDAQLR-----------A 93

Query: 121 GRAPGAMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQPDDGEDAPR 180
            R   A A      +     R  DG PRREEDDV PEEKRLRLLLE GSAQP+DGEDAPR
Sbjct: 94  ARTQRARAQTPQLRREDA--RAGDGWPRREEDDVPPEEKRLRLLLEGGSAQPEDGEDAPR 151

Query: 181 PGRKETGTQTGGDGRG 196
           PGR+ETGTQTGGDG+G
Sbjct: 152 PGREETGTQTGGDGKG 167


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 55.5 bits (132), Expect = 5e-08
 Identities = 54/199 (27%), Positives = 71/199 (35%), Gaps = 28/199 (14%)

Query: 33  PERAWPQAGDSDCLGQGRRAQRRPGPGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAP 92
           P  A PQ        +G+R  R    GV  +G  G++ AP +   P ++    P  +   
Sbjct: 473 PGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGE 532

Query: 93  RGPTEPALRRPSSAD--RPLAPGPSSSPGAGRAPGAMASPSGSSKATGKPRGRDGRPRRE 150
           RGP+  A  + ++ D  RP  PG   + G    PG  A P G    +G P G DGRP   
Sbjct: 533 RGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGD-AGPQGKVGPSGAP-GEDGRP--- 587

Query: 151 EDDVTPEEKRLRLLLEEGSAQPDDGEDAPR----PGRKETGTQTGGDGRGVSDAGAGVRG 206
                            G   P      P     PG K    + G  G        G+RG
Sbjct: 588 -----------------GPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRG 630

Query: 207 CRGCRGRGVGAAGGSVAGP 225
             G  G    A     AGP
Sbjct: 631 LPGKDGETGAAGPPGPAGP 649



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 60/210 (28%), Positives = 73/210 (34%), Gaps = 47/210 (22%)

Query: 48   QGRRAQRRPGPGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSAD 107
            +G R  + P       GA+G+   P SN  P     P P     P+G    +   P  A 
Sbjct: 884  KGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDS-GPPGRAG 942

Query: 108  RPLAPGPSSSPGAGRAPGAMASPSGSSKATGKP--------RGRDGRPRREEDDVTPEEK 159
             P   GP+  PG    PG      G S A G P        RG  G P +  +   P   
Sbjct: 943  EPGLQGPAGPPGEKGEPG----DDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPG-- 996

Query: 160  RLRLLLEEGSAQP----------DDGEDAP-----------RPGRKETGTQTGGDGRGVS 198
                 L   S +P          D G   P            PGR+ +    G DG    
Sbjct: 997  -----LPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGS---PGADGPPGR 1048

Query: 199  DAGAGVRGCRGCRGRGVGAAG--GSVAGPG 226
            D  AGV+G RG  G  VGA G  G    PG
Sbjct: 1049 DGAAGVKGDRGETG-AVGAPGAPGPPGSPG 1077



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 58/188 (30%), Positives = 71/188 (37%), Gaps = 38/188 (20%)

Query: 57  GPGV-SAVGASGQQ-----RAPESNERPAEEP-TPAPMPSSAPRGPTEPALRRPSSADRP 109
           GPG   A GA G+      R PE  + P  EP TP    S  P G    A   P +   P
Sbjct: 364 GPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPG---SPGPAG----ASGNPGTDGIP 416

Query: 110 LAPGPSSSPGAGRAPG--AMASPSGSSKATGK--PRGRDGRP-----RREEDDVTPEEKR 160
            A G + +PG   APG      P G   ATG   P+G+ G P     + E+         
Sbjct: 417 GAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQG-------- 468

Query: 161 LRLLLEEGSAQPDDGEDAPRPGRKETGTQTGGDGRGVSDAG-AGVRGCRGCRG-RGVGAA 218
                 +G   P   + AP P  +E      G+  GV   G  G RG  G RG  G    
Sbjct: 469 -----PKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGL 523

Query: 219 GGSVAGPG 226
            G    PG
Sbjct: 524 AGPKGAPG 531



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 53/161 (32%), Positives = 65/161 (40%), Gaps = 30/161 (18%)

Query: 6   GRPFSPPWAGRPSGCNLVGAGRRCRAWPERAWPQAGDSDCLG-QGRRAQRRPGPGVSAVG 64
           G+P     AG+P       AG R    P+ A    G     G +G R      PG+   G
Sbjct: 249 GKPGDDGEAGKPGK-----AGERGPPGPQGARGFPGTPGLPGVKGHRGY----PGLD--G 297

Query: 65  ASGQQRAPE---SNERPAEEPTPAPM-PSSAP--RGPTEPALR--------RPSSADRPL 110
           A G+  AP     +  P E  +P PM P   P  RG T PA          +P  A  P 
Sbjct: 298 AKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPG 357

Query: 111 APGPSSSPGAGRAPGAM--ASPSGSSKATGK--PRGRDGRP 147
             GP+  PG   APGA   A P+G+    G   PRG  G P
Sbjct: 358 PVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTP 398



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 72/244 (29%), Positives = 85/244 (34%), Gaps = 48/244 (19%)

Query: 5   SGRPFSPPWAGRPSGCNLVG----AGRRCRAWPERAWPQAGDSDCLG-QGRRAQRR---- 55
           +G P  P   G P    L G    AG + +  P  A  + G     G QG R Q      
Sbjct: 545 NGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGF 604

Query: 56  PGP-GVSA----VGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRR-----PSS 105
           PGP G +      G  G   AP     P ++       ++ P GP  PA  R     P  
Sbjct: 605 PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETG---AAGPPGPAGPAGERGEQGAPGP 661

Query: 106 ADRPLAPGPSSSPGAGRAPGAMASPSGSSKATG--KPRGRDGRPRREEDDVTPEEKRLRL 163
           +     PGP   PG G  PG    P G + A G   PRG  G P                
Sbjct: 662 SGFQGLPGPPGPPGEGGKPGDQGVP-GEAGAPGLVGPRGERGFPG--------------- 705

Query: 164 LLEEGSAQPDDGEDAPR--PGRKETGTQTGGDGRGVSDAGAGVRGCRGCRGRGVGAAGGS 221
             E GS     G   PR  PG   T    G  G        G  G +G  G   GAAG  
Sbjct: 706 --ERGSPGA-QGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGER-GAAG-- 759

Query: 222 VAGP 225
           +AGP
Sbjct: 760 IAGP 763



 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 53/181 (29%), Positives = 65/181 (35%), Gaps = 26/181 (14%)

Query: 64  GASGQQRAPESNERPAEEPTPA-PMPSSAPRGPTEPALRRPSSADRPLAPGPSSSPGAGR 122
           G  G++ AP    R  E  TP  P P   P  P  P L    +A   +A G     G G 
Sbjct: 138 GDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQ--MAGGFDEKAG-GA 194

Query: 123 APGAMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQP---------- 172
             G M  P G     G P G  G P  +     P E       E G + P          
Sbjct: 195 QLGVMQGPMGPMGPRGPP-GPAGAPGPQGFQGNPGEPG-----EPGVSGPMGPRGPPGPP 248

Query: 173 ----DDGEDAPRPGRKETGTQTGGDGRGVSDAGAGVRGCRGCRG-RGVGAAGGSVAGPGL 227
               DDGE A +PG+       G  G        G+ G +G RG  G+  A G    PG+
Sbjct: 249 GKPGDDGE-AGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGV 307

Query: 228 K 228
           K
Sbjct: 308 K 308



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 49/170 (28%), Positives = 65/170 (38%), Gaps = 27/170 (15%)

Query: 63  VGASGQQRAP-ESNERPAEEPTPAPMPSSA--PRGPTEPALRRPSSADRPLAPGPSSSPG 119
           VG  G + AP +   R    P   P P+ A   +G   P             PGP+ S G
Sbjct: 770 VGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGP-------------PGPAGSAG 816

Query: 120 AGRAPG--AMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQPDDGED 177
           A  APG      P G +   G P G DG+P  + +     +K      + G+  P     
Sbjct: 817 ARGAPGERGETGPPGPAGFAGPP-GADGQPGAKGEQGEAGQKG-----DAGAPGPQGPSG 870

Query: 178 APRPGRKETGTQTGGDGRGVSDAGAGVRGCRGCRGR-GVGAAGGSVAGPG 226
           AP P +  TG  TG  G   +    G  G  G  GR G   + G+   PG
Sbjct: 871 APGP-QGPTGV-TGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPG 918



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 59/248 (23%), Positives = 75/248 (30%), Gaps = 28/248 (11%)

Query: 6   GRPFSPPWAGRPSGCNLVGAGRRCRAWPERAWPQAGDSDCLG--QGRRAQRRPGPGVSAV 63
           G P +P   G P      G G    A     + +      LG  QG      P       
Sbjct: 156 GTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPA 215

Query: 64  GASGQQRAPESNERPAEEPTPAPMPSSAPRGP-----TEPALRRPSSADRPLAPGPSSSP 118
           GA G Q    +   P E     PM    P GP      +    +P  A     PGP  + 
Sbjct: 216 GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGAR 275

Query: 119 GAGRAPG-----------------AMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRL 161
           G    PG                   A   G    +G P G +G P        P E+  
Sbjct: 276 GFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSP-GENGSPGPMGPRGLPGERGR 334

Query: 162 RLLLEEGSAQPDDGEDAPR--PGRKETGTQTGGDGRGVSDAGAGVRGCRGCRG-RGVGAA 218
                   A+ +DG+  P   PG        G  G   +   AG  G RG  G +G    
Sbjct: 335 TGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGE 394

Query: 219 GGSVAGPG 226
            G+   PG
Sbjct: 395 PGTPGSPG 402



 Score = 35.4 bits (80), Expect = 0.050
 Identities = 43/155 (27%), Positives = 53/155 (34%), Gaps = 27/155 (17%)

Query: 6    GRPFSPPWAGRPSGCNLVGA-GRRCRAWPERAWPQAGDSDCLG----QGRRAQRRPG--P 58
            G P +P   G P      G  G R  A  +     +G +   G    QG R  +     P
Sbjct: 1065 GAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEP 1124

Query: 59   GVSAV----GASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGP 114
            G   +    G +G Q  P       ++    P   S PRGP  P              GP
Sbjct: 1125 GERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPV-------------GP 1171

Query: 115  SSSPGAGRAPGAMA--SPSGSSKATGKPRGRDGRP 147
            S   GA   PG +    P G S  TG P G  G P
Sbjct: 1172 SGKDGANGIPGPIGPPGPRGRSGETG-PAGPPGNP 1205


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 55.5 bits (132), Expect = 5e-08
 Identities = 54/199 (27%), Positives = 71/199 (35%), Gaps = 28/199 (14%)

Query: 33  PERAWPQAGDSDCLGQGRRAQRRPGPGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAP 92
           P  A PQ        +G+R  R    GV  +G  G++ AP +   P ++    P  +   
Sbjct: 404 PGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGE 463

Query: 93  RGPTEPALRRPSSAD--RPLAPGPSSSPGAGRAPGAMASPSGSSKATGKPRGRDGRPRRE 150
           RGP+  A  + ++ D  RP  PG   + G    PG  A P G    +G P G DGRP   
Sbjct: 464 RGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGD-AGPQGKVGPSGAP-GEDGRP--- 518

Query: 151 EDDVTPEEKRLRLLLEEGSAQPDDGEDAPR----PGRKETGTQTGGDGRGVSDAGAGVRG 206
                            G   P      P     PG K    + G  G        G+RG
Sbjct: 519 -----------------GPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRG 561

Query: 207 CRGCRGRGVGAAGGSVAGP 225
             G  G    A     AGP
Sbjct: 562 LPGKDGETGAAGPPGPAGP 580



 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 60/210 (28%), Positives = 73/210 (34%), Gaps = 47/210 (22%)

Query: 48   QGRRAQRRPGPGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSAD 107
            +G R  + P       GA+G+   P SN  P     P P     P+G    +   P  A 
Sbjct: 815  KGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDS-GPPGRAG 873

Query: 108  RPLAPGPSSSPGAGRAPGAMASPSGSSKATGKP--------RGRDGRPRREEDDVTPEEK 159
             P   GP+  PG    PG      G S A G P        RG  G P +  +   P   
Sbjct: 874  EPGLQGPAGPPGEKGEPG----DDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPG-- 927

Query: 160  RLRLLLEEGSAQP----------DDGEDAP-----------RPGRKETGTQTGGDGRGVS 198
                 L   S +P          D G   P            PGR+ +    G DG    
Sbjct: 928  -----LPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGS---PGADGPPGR 979

Query: 199  DAGAGVRGCRGCRGRGVGAAG--GSVAGPG 226
            D  AGV+G RG  G  VGA G  G    PG
Sbjct: 980  DGAAGVKGDRGETG-AVGAPGAPGPPGSPG 1008



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 58/188 (30%), Positives = 71/188 (37%), Gaps = 38/188 (20%)

Query: 57  GPGV-SAVGASGQQ-----RAPESNERPAEEP-TPAPMPSSAPRGPTEPALRRPSSADRP 109
           GPG   A GA G+      R PE  + P  EP TP    S  P G    A   P +   P
Sbjct: 295 GPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPG---SPGPAG----ASGNPGTDGIP 347

Query: 110 LAPGPSSSPGAGRAPG--AMASPSGSSKATGK--PRGRDGRP-----RREEDDVTPEEKR 160
            A G + +PG   APG      P G   ATG   P+G+ G P     + E+         
Sbjct: 348 GAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQG-------- 399

Query: 161 LRLLLEEGSAQPDDGEDAPRPGRKETGTQTGGDGRGVSDAG-AGVRGCRGCRG-RGVGAA 218
                 +G   P   + AP P  +E      G+  GV   G  G RG  G RG  G    
Sbjct: 400 -----PKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGL 454

Query: 219 GGSVAGPG 226
            G    PG
Sbjct: 455 AGPKGAPG 462



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 53/161 (32%), Positives = 65/161 (40%), Gaps = 30/161 (18%)

Query: 6   GRPFSPPWAGRPSGCNLVGAGRRCRAWPERAWPQAGDSDCLG-QGRRAQRRPGPGVSAVG 64
           G+P     AG+P       AG R    P+ A    G     G +G R      PG+   G
Sbjct: 180 GKPGDDGEAGKPGK-----AGERGPPGPQGARGFPGTPGLPGVKGHRGY----PGLD--G 228

Query: 65  ASGQQRAPE---SNERPAEEPTPAPM-PSSAP--RGPTEPALR--------RPSSADRPL 110
           A G+  AP     +  P E  +P PM P   P  RG T PA          +P  A  P 
Sbjct: 229 AKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPG 288

Query: 111 APGPSSSPGAGRAPGAM--ASPSGSSKATGK--PRGRDGRP 147
             GP+  PG   APGA   A P+G+    G   PRG  G P
Sbjct: 289 PVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTP 329



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 72/244 (29%), Positives = 85/244 (34%), Gaps = 48/244 (19%)

Query: 5   SGRPFSPPWAGRPSGCNLVG----AGRRCRAWPERAWPQAGDSDCLG-QGRRAQRR---- 55
           +G P  P   G P    L G    AG + +  P  A  + G     G QG R Q      
Sbjct: 476 NGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGF 535

Query: 56  PGP-GVSA----VGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRR-----PSS 105
           PGP G +      G  G   AP     P ++       ++ P GP  PA  R     P  
Sbjct: 536 PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETG---AAGPPGPAGPAGERGEQGAPGP 592

Query: 106 ADRPLAPGPSSSPGAGRAPGAMASPSGSSKATG--KPRGRDGRPRREEDDVTPEEKRLRL 163
           +     PGP   PG G  PG    P G + A G   PRG  G P                
Sbjct: 593 SGFQGLPGPPGPPGEGGKPGDQGVP-GEAGAPGLVGPRGERGFPG--------------- 636

Query: 164 LLEEGSAQPDDGEDAPR--PGRKETGTQTGGDGRGVSDAGAGVRGCRGCRGRGVGAAGGS 221
             E GS     G   PR  PG   T    G  G        G  G +G  G   GAAG  
Sbjct: 637 --ERGSPGA-QGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGER-GAAG-- 690

Query: 222 VAGP 225
           +AGP
Sbjct: 691 IAGP 694



 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 53/181 (29%), Positives = 65/181 (35%), Gaps = 26/181 (14%)

Query: 64  GASGQQRAPESNERPAEEPTPA-PMPSSAPRGPTEPALRRPSSADRPLAPGPSSSPGAGR 122
           G  G++ AP    R  E  TP  P P   P  P  P L    +A   +A G     G G 
Sbjct: 69  GDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQ--MAGGFDEKAG-GA 125

Query: 123 APGAMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQP---------- 172
             G M  P G     G P G  G P  +     P E       E G + P          
Sbjct: 126 QLGVMQGPMGPMGPRGPP-GPAGAPGPQGFQGNPGEPG-----EPGVSGPMGPRGPPGPP 179

Query: 173 ----DDGEDAPRPGRKETGTQTGGDGRGVSDAGAGVRGCRGCRG-RGVGAAGGSVAGPGL 227
               DDGE A +PG+       G  G        G+ G +G RG  G+  A G    PG+
Sbjct: 180 GKPGDDGE-AGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGV 238

Query: 228 K 228
           K
Sbjct: 239 K 239



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 49/170 (28%), Positives = 65/170 (38%), Gaps = 27/170 (15%)

Query: 63  VGASGQQRAP-ESNERPAEEPTPAPMPSSA--PRGPTEPALRRPSSADRPLAPGPSSSPG 119
           VG  G + AP +   R    P   P P+ A   +G   P             PGP+ S G
Sbjct: 701 VGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGP-------------PGPAGSAG 747

Query: 120 AGRAPG--AMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQPDDGED 177
           A  APG      P G +   G P G DG+P  + +     +K      + G+  P     
Sbjct: 748 ARGAPGERGETGPPGPAGFAGPP-GADGQPGAKGEQGEAGQKG-----DAGAPGPQGPSG 801

Query: 178 APRPGRKETGTQTGGDGRGVSDAGAGVRGCRGCRGR-GVGAAGGSVAGPG 226
           AP P +  TG  TG  G   +    G  G  G  GR G   + G+   PG
Sbjct: 802 APGP-QGPTGV-TGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPG 849



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 59/248 (23%), Positives = 75/248 (30%), Gaps = 28/248 (11%)

Query: 6   GRPFSPPWAGRPSGCNLVGAGRRCRAWPERAWPQAGDSDCLG--QGRRAQRRPGPGVSAV 63
           G P +P   G P      G G    A     + +      LG  QG      P       
Sbjct: 87  GTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPA 146

Query: 64  GASGQQRAPESNERPAEEPTPAPMPSSAPRGP-----TEPALRRPSSADRPLAPGPSSSP 118
           GA G Q    +   P E     PM    P GP      +    +P  A     PGP  + 
Sbjct: 147 GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGAR 206

Query: 119 GAGRAPG-----------------AMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRL 161
           G    PG                   A   G    +G P G +G P        P E+  
Sbjct: 207 GFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSP-GENGSPGPMGPRGLPGERGR 265

Query: 162 RLLLEEGSAQPDDGEDAPR--PGRKETGTQTGGDGRGVSDAGAGVRGCRGCRG-RGVGAA 218
                   A+ +DG+  P   PG        G  G   +   AG  G RG  G +G    
Sbjct: 266 TGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGE 325

Query: 219 GGSVAGPG 226
            G+   PG
Sbjct: 326 PGTPGSPG 333



 Score = 35.4 bits (80), Expect = 0.050
 Identities = 43/155 (27%), Positives = 53/155 (34%), Gaps = 27/155 (17%)

Query: 6    GRPFSPPWAGRPSGCNLVGA-GRRCRAWPERAWPQAGDSDCLG----QGRRAQRRPG--P 58
            G P +P   G P      G  G R  A  +     +G +   G    QG R  +     P
Sbjct: 996  GAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEP 1055

Query: 59   GVSAV----GASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGP 114
            G   +    G +G Q  P       ++    P   S PRGP  P              GP
Sbjct: 1056 GERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPV-------------GP 1102

Query: 115  SSSPGAGRAPGAMA--SPSGSSKATGKPRGRDGRP 147
            S   GA   PG +    P G S  TG P G  G P
Sbjct: 1103 SGKDGANGIPGPIGPPGPRGRSGETG-PAGPPGNP 1136


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 54.7 bits (130), Expect = 8e-08
 Identities = 72/244 (29%), Positives = 91/244 (37%), Gaps = 27/244 (11%)

Query: 5    SGRPFSPPWAGRPSGCNLVGA-GRRCRAWPERAWPQAGDSDCLG----QGRRAQRRP--G 57
            +G P +P   G P G    GA G +    P       G S   G    QG + +R    G
Sbjct: 809  AGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGG 868

Query: 58   PGVSAV-GASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLA----- 111
            PG +   GA G    P SN  P     P P  S    GP  PA    +     ++     
Sbjct: 869  PGAAGFPGARGLPGPPGSNGNPGP---PGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGD 925

Query: 112  ---PGPSSSPGAGRAPGAMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEG 168
               PG   SPGA   PGA   P G +  TG  RG  G P       +P  + ++    + 
Sbjct: 926  AGQPGEKGSPGAQGPPGA-PGPLGIAGITG-ARGLAGPPGMPGPRGSPGPQGVKGESGKP 983

Query: 169  SAQPDDGEDAP-----RPGRKETGTQTGGDGRGVSDAGAGVRGCRGCRG-RGVGAAGGSV 222
             A    GE  P      PG   T  + G DG   SD   G  G  G +G RG   + G+ 
Sbjct: 984  GANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAP 1043

Query: 223  AGPG 226
              PG
Sbjct: 1044 GAPG 1047



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 51/180 (28%), Positives = 59/180 (32%), Gaps = 37/180 (20%)

Query: 56  PG-PGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGP 114
           PG PG  A G  G   +P SN  P +   P P   +  +GP  P    P     P   G 
Sbjct: 344 PGSPG--AKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGP----PGINGSPGGKGE 397

Query: 115 SSSPGAGRAPGAMAS--PSGSSKATGKP--RGRDGRPRREEDDVTPEEKRLRLLLEEGSA 170
               G   APG M +  P G + A G P  RG  G P +                     
Sbjct: 398 MGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGK--------------------- 436

Query: 171 QPDDGEDAPRPGRKETGT-----QTGGDGRGVSDAGAGVRGCRGCRGRGVGAAGGSVAGP 225
               GE  PR  R E G        G DG+  S    G  G  G  G          AGP
Sbjct: 437 NGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGP 496



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 58/191 (30%), Positives = 66/191 (34%), Gaps = 50/191 (26%)

Query: 56   PGPGVSAVGASGQQRAPESNERPAEEPTPA-----PMPSSAPRGPTEPALRR-------- 102
            PGP V   G SG  R       PA  P PA     P P   PRG       R        
Sbjct: 1052 PGP-VGPAGKSGD-RGESGPAGPAGAPGPAGSRGAPGPQG-PRGDKGETGERGAAGIKGH 1108

Query: 103  ---PSSADRPLAPGPSSSPGAGRAPGAMASPSGSSKATGKPRGRDGRPRREEDDVTPEEK 159
               P +   P +PGP+   GA  +PG  A P G    +G P G+DG              
Sbjct: 1109 RGFPGNPGAPGSPGPAGQQGAIGSPGP-AGPRGPVGPSGPP-GKDGT------------- 1153

Query: 160  RLRLLLEEGSAQPDD-GEDAPRPGRKETGTQTGGDGRGVSDAGAGVRGCRGCRGRGVGAA 218
                     S  P   G   PR  R E G++ G  G        G  G  G    GVGAA
Sbjct: 1154 ---------SGHPGPIGPPGPRGNRGERGSE-GSPGHPGQPGPPGPPGAPGPCCGGVGAA 1203

Query: 219  -----GGSVAG 224
                 GG  AG
Sbjct: 1204 AIAGIGGEKAG 1214



 Score = 35.8 bits (81), Expect = 0.039
 Identities = 50/196 (25%), Positives = 63/196 (32%), Gaps = 24/196 (12%)

Query: 49  GRRAQRRPGPGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADR 108
           G+   R P   +   G +GQ         P       P  S   RG T P    P  A  
Sbjct: 756 GKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGP----PGPAGF 811

Query: 109 PLAPGPSSSPGA------------GRAPGAMASPSGSSKATGKP-----RGRDGRPRREE 151
           P APG +  PG             G  PG +A P G S   G P     +G  G P    
Sbjct: 812 PGAPGQNGEPGGKGERGAPGEKGEGGPPG-VAGPPGGSGPAGPPGPQGVKGERGSPGGPG 870

Query: 152 DDVTPEEKRLRLLLEEGSAQPDDGEDAPRPGRKETGTQTGGDGRGVSDAGAGVRGCRGCR 211
               P  + L       +  P     +  PG+       G  G   S   +G +G  G  
Sbjct: 871 AAGFPGARGLP-GPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQP 929

Query: 212 G-RGVGAAGGSVAGPG 226
           G +G   A G    PG
Sbjct: 930 GEKGSPGAQGPPGAPG 945



 Score = 35.4 bits (80), Expect = 0.050
 Identities = 44/175 (25%), Positives = 54/175 (30%), Gaps = 32/175 (18%)

Query: 64  GASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRR-----------PSSADRPLAP 112
           G  G Q  P  N     +  P P      +G T P   +           P    +P  P
Sbjct: 600 GGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEP 659

Query: 113 GPSSSPGAGRAPGAMASPSGSSKATGK--PRGRDGRPRREEDDVTPEEKRLRLLLEEGSA 170
           GP    GA  APG      G + A G+  P G  G P               L    G  
Sbjct: 660 GPKGDAGAPGAPGG----KGDAGAPGERGPPGLAGAP--------------GLRGGAGPP 701

Query: 171 QPDDGEDAP-RPGRKETGTQTGGDGRGVSDAGAGVRGCRGCRGRGVGAAGGSVAG 224
            P+ G+ A   PG        G  G      G G  G +G +G   G     V G
Sbjct: 702 GPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPG 756



 Score = 34.7 bits (78), Expect = 0.086
 Identities = 47/181 (25%), Positives = 55/181 (30%), Gaps = 21/181 (11%)

Query: 58  PGVSAV----GASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPG 113
           PGV       G  G    P +N  P             P GP      +  + +R  APG
Sbjct: 455 PGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERG-APG 513

Query: 114 PSSSPGAGRAPGAMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQPD 173
           P+   GA   PG    P G        RG  G P     D  P     +   E G   P 
Sbjct: 514 PAGPRGAAGEPGRDGVPGGPGM-----RGMPGSPGGPGSDGKPGPPGSQ--GESGRPGP- 565

Query: 174 DGEDAPR--------PGRKETGTQTGGDGRGVSDAGAGVRGCRGCRGRGVGAAGGSVAGP 225
            G   PR        PG K      G +G      G G +G  G  G           GP
Sbjct: 566 PGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGP 625

Query: 226 G 226
           G
Sbjct: 626 G 626



 Score = 33.9 bits (76), Expect = 0.15
 Identities = 59/222 (26%), Positives = 75/222 (33%), Gaps = 38/222 (17%)

Query: 26  GRRCRAWPERAWPQAGDSDCLGQGRRAQRR-PGPGVSAVGASGQQRAPESNERPAEEPTP 84
           G  C   P+   P A      GQG +  +  PGP     G  G+   P    +P    +P
Sbjct: 82  GECCAVCPQP--PTAPTRPPNGQGPQGPKGDPGPP----GIPGRNGDPGIPGQPGSPGSP 135

Query: 85  AP--MPSSAPRGPTEPALRRPSS------ADRPLA--------PGPSSSPGAGRAPGAMA 128
            P  +  S P GP   + +  S       A   LA        PGP   PG    PG+  
Sbjct: 136 GPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPG 195

Query: 129 SPSGSSKATGKP-RGRDGRPRREEDDVTPEEKRLRLLLEEGSAQPDDGEDAP-RPGRKET 186
           SP G     G+P +     P      + P           G A  D     P RPG +  
Sbjct: 196 SP-GYQGPPGEPGQAGPSGPPGPPGAIGP----------SGPAGKDGESGRPGRPGERGL 244

Query: 187 GTQTGGDGRGVSDAGAGVRGCRGCRGRGVGAAGGSVAGPGLK 228
               G  G        G++G RG  GR      G    PGLK
Sbjct: 245 PGPPGIKGPAGIPGFPGMKGHRGFDGR--NGEKGETGAPGLK 284



 Score = 32.3 bits (72), Expect = 0.43
 Identities = 59/233 (25%), Positives = 77/233 (33%), Gaps = 55/233 (23%)

Query: 11   PPWAGRPSGCNLVGAGRRCRAWPERAWPQA--------GDSDCLGQGRRAQRRPGPGVSA 62
            PP A  P G   +   R     P    P+         G+S   G    +  R  PG   
Sbjct: 940  PPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQG 999

Query: 63   V-GASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPSSSPGAG 121
            + G +G    P  +  P  +  P    S   +G            DR    G + SPGA 
Sbjct: 1000 LPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKG------------DR----GENGSPGAP 1043

Query: 122  RAPGAMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQPDDGEDAPRP 181
             APG    P         P G+ G  R E     P           G+  P     AP P
Sbjct: 1044 GAPGHPGPPGPVG-----PAGKSG-DRGESGPAGP----------AGAPGPAGSRGAPGP 1087

Query: 182  -GRKETGTQTGGDGRGVSDAGAGVRGCRGCRGR-----GVGAAG--GSVAGPG 226
             G +    +TG  G       AG++G RG  G        G AG  G++  PG
Sbjct: 1088 QGPRGDKGETGERG------AAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPG 1134


>gi|91208420 bassoon protein [Homo sapiens]
          Length = 3926

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 45/149 (30%), Positives = 57/149 (38%), Gaps = 12/149 (8%)

Query: 57  GPGVSAVGASGQQRAPESNERPAEEPTPAP---MPSSAPRGPTE-PALRRPSSADRPLAP 112
           G  VS  G +G    P     P   P P P    P SAP G  + PA     S   P  P
Sbjct: 2   GNEVSLEGGAGDGPLPPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVP 61

Query: 113 GPSSSPGAGRAPGAMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQP 172
           GP   PG G  PG+ +      +  G  R     P ++    TP  +  R    E  AQ 
Sbjct: 62  GPGPGPGPGPGPGSTSRRLDPKEPLGNQRAASPTP-KQASATTPGHESPR----ETRAQG 116

Query: 173 DDGEDAPRPGRK---ETGTQTGGDGRGVS 198
             G++A  P R    ++ TQ  G    VS
Sbjct: 117 PAGQEADGPRRTLQVDSRTQRSGRSPSVS 145



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 34/123 (27%), Positives = 52/123 (42%), Gaps = 22/123 (17%)

Query: 63   VGASGQQRAPE-------SNERPAEEPT----PAPMPSSAPRGPTEPALRRPSSADRPL- 110
            +G +G  R P        S+  PAE P     PA   +    GP+ P +   ++ + PL 
Sbjct: 2253 LGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPLP 2312

Query: 111  ----------APGPSSSPGAGRAPGAMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKR 160
                      A  P+ +P AG+ P A A+P G S A  +P        +EE     +E+ 
Sbjct: 2313 TTTPAAIKEAAGAPAPAPLAGQKPPADAAPGGGSGALSRPGFEKEEASQEERQRKQQEQL 2372

Query: 161  LRL 163
            L+L
Sbjct: 2373 LQL 2375



 Score = 35.8 bits (81), Expect = 0.039
 Identities = 29/104 (27%), Positives = 40/104 (38%), Gaps = 16/104 (15%)

Query: 38   PQAGDSDCLGQGRRAQRRPGPGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTE 97
            PQ G S   G        P       G+ G  +AP+    P  +P P P P+    G   
Sbjct: 3821 PQPGPSTATGPQPAG---PPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAG--- 3874

Query: 98   PALRRPSSADRPLAPG-PSSSPGA-GRAPGAMASPSGSSKATGK 139
                RP        PG P+  PGA G +  +   P G+++  GK
Sbjct: 3875 ---ARPGG-----TPGAPAGQPGADGESVFSKILPGGAAEQAGK 3910



 Score = 34.3 bits (77), Expect = 0.11
 Identities = 37/148 (25%), Positives = 53/148 (35%), Gaps = 13/148 (8%)

Query: 4    LSGRPFSP-PWAGRPSGCNLVGAGRRCRAWPERAWPQAG-----DSDCLGQGR-RAQRRP 56
            L GR  +P P   +      + +G   R  P+    Q G         L Q R + Q +P
Sbjct: 3747 LQGRQAAPGPQQSQSPSSRQIPSGAASRQ-PQTQQQQQGLGLQPPQQALTQARLQQQSQP 3805

Query: 57   GPGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLA----- 111
                SA  AS     P+     A  P PA  P +     ++   + P     P A     
Sbjct: 3806 TTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPG 3865

Query: 112  PGPSSSPGAGRAPGAMASPSGSSKATGK 139
            PGP+      R  G   +P+G   A G+
Sbjct: 3866 PGPAGVKAGARPGGTPGAPAGQPGADGE 3893



 Score = 33.9 bits (76), Expect = 0.15
 Identities = 24/84 (28%), Positives = 36/84 (42%), Gaps = 6/84 (7%)

Query: 61   SAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPSSSPGA 120
            +   A      P + ++P  +P PAP  S+   GPT+       +   P  PGPS+ P  
Sbjct: 3037 ATAAAPATPSGPTAFQQPRFQP-PAPQYSAGSGGPTQNGF---PAHQAPTYPGPSTYPAP 3092

Query: 121  GRAPGAM--ASPSGSSKATGKPRG 142
               PGA   A P   ++   +P G
Sbjct: 3093 AFPPGASYPAEPGLPNQQAFRPTG 3116



 Score = 33.5 bits (75), Expect = 0.19
 Identities = 48/179 (26%), Positives = 67/179 (37%), Gaps = 35/179 (19%)

Query: 48   QGRRAQRRPGPGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAPRG----PTEPALRRP 103
            QGR+A   PGP         Q ++P S + P+   +  P      +G    P + AL + 
Sbjct: 3748 QGRQAA--PGPQ--------QSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQA 3797

Query: 104  SSADRPLAPGPSSSPGAGRAPGAMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRL 163
                +       S+P A + P     P G S ATG      G PR E+ + +        
Sbjct: 3798 RLQQQSQPTTRGSAPAASQ-PAGKPQP-GPSTATGPQPA--GPPRAEQTNGS-------- 3845

Query: 164  LLEEGSAQPDDGEDAPRPGRKETGTQTGGDGRGVSDAGAGVRGCRGCRGRGVGAAGGSV 222
               +G+A+      AP+ GR        G G     AGA   G  G      GA G SV
Sbjct: 3846 ---KGTAK------APQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQPGADGESV 3895



 Score = 32.0 bits (71), Expect = 0.56
 Identities = 27/96 (28%), Positives = 33/96 (34%), Gaps = 20/96 (20%)

Query: 53  QRRPGPGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAP 112
           Q +P P            + E+  +P       P P  AP   TEP  R           
Sbjct: 374 QGQPAPSKGTPKIVFNDASKEAGPKPLGS---GPGPGPAPGAKTEPGARM---------- 420

Query: 113 GPSSSPGAGRAPGAMASP-------SGSSKATGKPR 141
           GP S PGA    G   SP         +SKA  KP+
Sbjct: 421 GPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPK 456



 Score = 29.6 bits (65), Expect = 2.8
 Identities = 31/113 (27%), Positives = 45/113 (39%), Gaps = 16/113 (14%)

Query: 8   PFSPPWAGRPSGCNLVGAGRRCRAWPERAWPQAGDSDCLGQGRRAQRRP-GPGVSAVGAS 66
           P  PP + +P     VGA       P RA   +G S    +G +   +P GP  +     
Sbjct: 530 PLPPPTSQQPP----VGA-------PHRA---SGTSPLKQKGPQGLGQPSGPLPAKASPL 575

Query: 67  GQQRAP-ESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPSSSP 118
             + +P  S   P  +P  A  PS  P    E   R P+ A+    P P ++P
Sbjct: 576 STKASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTP 628



 Score = 28.9 bits (63), Expect = 4.7
 Identities = 19/67 (28%), Positives = 24/67 (35%), Gaps = 1/67 (1%)

Query: 77  RPAEEPTPAPMPSSA-PRGPTEPALRRPSSADRPLAPGPSSSPGAGRAPGAMASPSGSSK 135
           +P  +    P PS   P+     A +          PGP  +PGA   PGA   P     
Sbjct: 368 QPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKTEPGARMGPGSGPG 427

Query: 136 ATGKPRG 142
           A  K  G
Sbjct: 428 ALPKTGG 434



 Score = 28.5 bits (62), Expect = 6.2
 Identities = 33/132 (25%), Positives = 45/132 (34%), Gaps = 9/132 (6%)

Query: 33  PERAWPQAGDSDCLGQGRRAQRRPGPGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAP 92
           P  A P  G     G G+      G G      + +  A      P   P P P P S  
Sbjct: 18  PGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPGSTS 77

Query: 93  R--GPTEPALRRPSSADRP-----LAPGPSSSPGAGRAPGAMASPSGSSKATGKPRGRDG 145
           R   P EP   + +++  P       PG   SP   RA G     +   + T +   R  
Sbjct: 78  RRLDPKEPLGNQRAASPTPKQASATTPG-HESPRETRAQGPAGQEADGPRRTLQVDSRTQ 136

Query: 146 RPRREEDDVTPE 157
           R  R    V+P+
Sbjct: 137 RSGR-SPSVSPD 147


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 49/149 (32%), Positives = 63/149 (42%), Gaps = 19/149 (12%)

Query: 78   PAEEPTPAPMP--SSAPRGPTEPALRRPSSADRPLAPGPSSSPGAGRAPGAMASPSGSSK 135
            P EEP+P P P   S    PTEP +  P+    PLA  P  SP     P A +  S   K
Sbjct: 4910 PPEEPSPPPSPLAPSPASPPTEPLVELPT---EPLAEPPVPSP----LPLASSPESARPK 4962

Query: 136  ATGKP--RGRDGRPRREEDDVTPEEKRLRLLL--EEGSAQPDDGEDAPRPGRKETGTQTG 191
               +P   G D RP R +       KRLRLLL  ++GS + +D  +      ++ GT   
Sbjct: 4963 PRARPPEEGEDSRPPRLKKWKGVRWKRLRLLLTIQKGSGRQEDEREVAE-FMEQLGTALR 5021

Query: 192  GDGRGVSDAGAGVRGCRGCRGRGVGAAGG 220
             D          +R C  C   G GA  G
Sbjct: 5022 PD-----KVPRDMRRCCFCHEEGDGATDG 5045



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 30/103 (29%), Positives = 43/103 (41%), Gaps = 20/103 (19%)

Query: 38   PQAGDSDCLGQGRRAQRRP-----------GPGVSAVGASGQQRAPESNERPAEEPTP-A 85
            PQ G    LG G R Q  P           GP +  V  +    +P+  +RP++ P+P +
Sbjct: 4269 PQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSS 4328

Query: 86   PMPSSAPRGPTEPALRRPSSADRPLAPGPSSSPGAGRAPGAMA 128
             +P+ A   PT P   +P         GP+  P  GR   A A
Sbjct: 4329 QLPTEAQLPPTHPGTPKPQ--------GPTLEPPPGRVSPAAA 4363



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 30/114 (26%), Positives = 47/114 (41%), Gaps = 13/114 (11%)

Query: 78  PAEEPTPAPMPSSAPRGPTEPALRR-PSSADRPLAPGPSSSPGAGRAPGAMASPSGSSKA 136
           P EE   +P P  +P  P   A R  P   + PL+P P  SP        ++ P  +S+ 
Sbjct: 575 PPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESP--------LSPPPEASRL 626

Query: 137 TGKPRGRDGRPRREEDDVTPEEKRLRL----LLEEGSAQPDDGEDAPRPGRKET 186
           +  P      P  EE  ++P  +  RL    ++   S  P++   +P P    T
Sbjct: 627 SPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPT 680



 Score = 36.6 bits (83), Expect = 0.023
 Identities = 51/190 (26%), Positives = 64/190 (33%), Gaps = 24/190 (12%)

Query: 76   ERPAEEPTPAPMPS-SAPRGPTEPALRRPSSADRPLAP-----GPSSSPGAGRAPGAMAS 129
            E  A  P P+PM   S P     PAL   S      AP      P S P  G+ PG++AS
Sbjct: 1087 EPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLAS 1146

Query: 130  PSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQPDDGEDAPR-PGRKETGT 188
                S     P         E   VTP E         G   P + ++ PR P      T
Sbjct: 1147 ELKGSPVLLDP--------EELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPT 1198

Query: 189  QTGGD------GRGVSDAGAGVRGCRGCRGRGVGAAGGSVAGPGLKLVTERQLRRARSDS 242
                D           DA A   G     G      GGS++   ++L     +  AR + 
Sbjct: 1199 LIKSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGGSLS---MELGVSTDVSPARDEG 1255

Query: 243  SRRPPRRQLP 252
            S R     LP
Sbjct: 1256 SLRLCTDSLP 1265



 Score = 35.4 bits (80), Expect = 0.050
 Identities = 33/110 (30%), Positives = 45/110 (40%), Gaps = 6/110 (5%)

Query: 78  PAEEPTPAPMPSSAPRGPTEPALR-RPSSADRPLAPGPSSSPGAGRAPGAMAS-PSGSSK 135
           P EE   +P P  +P  P   A R  P   D P +P P  SP +     ++ S P   S 
Sbjct: 665 PPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESP 724

Query: 136 ATGKPRGRDGRPRREEDDVT--PEEKRLRLLLEEG--SAQPDDGEDAPRP 181
               P      PR E   ++  PEE  L    EE   S Q ++   +P+P
Sbjct: 725 LLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQP 774



 Score = 34.7 bits (78), Expect = 0.086
 Identities = 29/111 (26%), Positives = 41/111 (36%), Gaps = 10/111 (9%)

Query: 73  ESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPSSSPGAGRAPGAMASPSG 132
           ES   P EE  P+P   +    P E +   P   + PL+P P   P         + P  
Sbjct: 517 ESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELP--------TSPPPE 568

Query: 133 SSKATGKPRGRDGRPRREEDDVTPEEKRLRLL--LEEGSAQPDDGEDAPRP 181
           +S+ +  P      P  EE  ++P  +  RL    EE    P   E    P
Sbjct: 569 ASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSP 619



 Score = 34.3 bits (77), Expect = 0.11
 Identities = 26/105 (24%), Positives = 35/105 (33%), Gaps = 16/105 (15%)

Query: 78  PAEEPTPAPMPSSAPRGPTEPALR----------RPSSADRPLAPGPSSSPGAGRAPGAM 127
           P E+   +P P  +P  P     R           P   + PL+P P  SP +     + 
Sbjct: 629 PPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASR 688

Query: 128 ASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQP 172
            SP      T  P      P        PE+  + L LEE    P
Sbjct: 689 LSPPPEDSPTSPP------PEDSPASPPPEDSLMSLPLEESPLLP 727



 Score = 33.9 bits (76), Expect = 0.15
 Identities = 34/130 (26%), Positives = 44/130 (33%), Gaps = 15/130 (11%)

Query: 58  PGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPT----EPALRRPSSADRPLAPG 113
           P    V   GQ +         +EP P    +  P G      EP L  P + + PL P 
Sbjct: 385 PDALYVACQGQPKGGHVTSMQPKEPGPLQCEAK-PLGKAGVQLEPQLEAPLNEEMPLLPP 443

Query: 114 PSSSPGAGRAPGAMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLL--LEEGSAQ 171
           P  SP        ++ P   S  +  P      P  EE   +P  + L L   LEE    
Sbjct: 444 PEESP--------LSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLS 495

Query: 172 PDDGEDAPRP 181
           P   E    P
Sbjct: 496 PPPEESPLSP 505



 Score = 32.7 bits (73), Expect = 0.33
 Identities = 24/92 (26%), Positives = 33/92 (35%), Gaps = 2/92 (2%)

Query: 72   PESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAP-GPSSSPGAGRAPGAMASP 130
            P     P +E    P P   PR P  P          P+ P  P SSP   + P  + SP
Sbjct: 4267 PGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSP 4326

Query: 131  SGSSKATGK-PRGRDGRPRREEDDVTPEEKRL 161
            S       + P    G P+ +   + P   R+
Sbjct: 4327 SSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRV 4358



 Score = 30.0 bits (66), Expect = 2.1
 Identities = 26/105 (24%), Positives = 41/105 (39%), Gaps = 6/105 (5%)

Query: 77  RPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPSSSPGAGRAPGAMASPSGSSKA 136
           RP EE   +P P  +P  P   +       + PL+P P  SP +      ++ P  +S  
Sbjct: 487 RPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSP-PEESPPSPALETPLSPPPEASPL 545

Query: 137 TGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQPDDGEDAPRP 181
           +         P  EE   +P  +  RL     S  P++   +P P
Sbjct: 546 SPPFEESPLSPPPEELPTSPPPEASRL-----SPPPEESPMSPPP 585



 Score = 29.6 bits (65), Expect = 2.8
 Identities = 19/54 (35%), Positives = 22/54 (40%), Gaps = 13/54 (24%)

Query: 76  ERPAEEPTPAPMPSSAPRGPT-----------EPALRRPSSADRPLAPGPSSSP 118
           E+P EEP   P P   P  P            EPAL  P   + PL+P P   P
Sbjct: 865 EKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEP--GEPPLSPLPEELP 916



 Score = 29.6 bits (65), Expect = 2.8
 Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 8/56 (14%)

Query: 68   QQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSS-----ADRPLAPGPSSSP 118
            + ++P    RP E P   P  + AP  P+ P + RP S     A  PL P P   P
Sbjct: 2339 EPQSPGLGLRPQEPP---PAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPP 2391



 Score = 28.5 bits (62), Expect = 6.2
 Identities = 22/64 (34%), Positives = 29/64 (45%), Gaps = 6/64 (9%)

Query: 78   PAEEPTP-APMPSSAPRGPTEPALRRP--SSADRPLAP---GPSSSPGAGRAPGAMASPS 131
            P+++P   AP     PR PT P    P  S    P  P   G SS PGAG+      +P 
Sbjct: 2172 PSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPP 2231

Query: 132  GSSK 135
            G+ +
Sbjct: 2232 GTPR 2235



 Score = 28.5 bits (62), Expect = 6.2
 Identities = 20/65 (30%), Positives = 27/65 (41%), Gaps = 3/65 (4%)

Query: 53   QRRPGPGVS---AVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRP 109
            Q++ GPGV    A+G   Q   P S+ +       +P P   P+G   PA         P
Sbjct: 3756 QQQQGPGVQTNQALGPKPQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHP 3815

Query: 110  LAPGP 114
             A GP
Sbjct: 3816 GALGP 3820


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 49.3 bits (116), Expect = 3e-06
 Identities = 54/186 (29%), Positives = 65/186 (34%), Gaps = 24/186 (12%)

Query: 48  QGRRAQRRPGPGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRR----- 102
           +G    + PG      G SG+  AP S      +  P P+    P GP     +R     
Sbjct: 415 RGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGE 474

Query: 103 PSSADRPLAPGPSSSPGAGRAPGA--MASPSGSSKATGK-----PRGRDGRPRREEDDVT 155
           P     P  PG    PG+   PGA  +A P G +   G      P+G  G   R  +   
Sbjct: 475 PGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGL 534

Query: 156 PEEKRLRLLLEEGSAQPDDGEDAPRPGRKETGTQTGGDGRGVSDAGAGVRGCRGCRG--R 213
           P  K   L    GS  PD     P P         G DGR       G RG  G  G   
Sbjct: 535 PGAK--GLTGSPGSPGPDGKTGPPGP--------AGQDGRPGPPGPPGARGQAGVMGFPG 584

Query: 214 GVGAAG 219
             GAAG
Sbjct: 585 PKGAAG 590



 Score = 45.4 bits (106), Expect = 5e-05
 Identities = 56/166 (33%), Positives = 62/166 (37%), Gaps = 24/166 (14%)

Query: 78  PAEEPTPAPMPS----SAPRGPTEPALRRPSSADR--PLAPGP---SSSPGAGRAPGAMA 128
           P   P PA  P     S P GP  P   R +  DR  P  PGP   +  PGA   PGA  
Sbjct: 768 PIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKG 827

Query: 129 SPSGSSKATGK-----PRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQPDDGEDAP-RPG 182
            P G + A G      P G  G P    +   P  K  R     GSA P      P   G
Sbjct: 828 EP-GDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGAR-----GSAGPPGATGFPGAAG 881

Query: 183 RKETGTQTGGDGRGVSDAGAGVRGCRGCRGRGVGAAG--GSVAGPG 226
           R      +G  G       AG  G +G RG   G AG  G V  PG
Sbjct: 882 RVGPPGPSGNAGPPGPPGPAGKEGGKGPRGE-TGPAGRPGEVGPPG 926



 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 73/255 (28%), Positives = 90/255 (35%), Gaps = 52/255 (20%)

Query: 5    SGRPFSPPWAGRPSGCNLVG----AGRRCRAWPERAWPQAGDSDCLGQG--RRAQRRPGP 58
            +G P  P  AG+  G    G    AGR     P      AG+    G      A   PGP
Sbjct: 892  AGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGP 951

Query: 59   -GVSA----VGASGQ--QRAPESNERPAEEP-TPAPMPSSAPRGPTEPA-----LRRPSS 105
             G++     VG  GQ  +R       P+ EP    P  +S  RGP  P         P  
Sbjct: 952  QGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGE 1011

Query: 106  ADRPLAPGPSSSPGAGRAPGAM--------ASPSGSSKATGK-----PRGRDGRPRREED 152
            + R  APG   SPG   +PGA         A P G+  A G      P G+ G  R E  
Sbjct: 1012 SGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSG-DRGETG 1070

Query: 153  DVTPEEKRLRLLLEEGSAQPDDGEDAPRPGRKETGTQTGGDGRGVSDAGAGVRGCRGCRG 212
               P        +    A+   G   PR  + ETG Q             G RG +G RG
Sbjct: 1071 PAGPAGP-----VGPVGARGPAGPQGPRGDKGETGEQ-------------GDRGIKGHRG 1112

Query: 213  -RGVGAAGGSVAGPG 226
              G+    G    PG
Sbjct: 1113 FSGLQGPPGPPGSPG 1127



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 55/195 (28%), Positives = 70/195 (35%), Gaps = 49/195 (25%)

Query: 72  PESNERPAEEPTPA---PMPSSAPRGPTEPA--LRRPSSADRPLAPGPSSSPGAGRAPG- 125
           P+ +E P ++ T     P   + PRGP  PA    R     +P  PGP   PG    PG 
Sbjct: 96  PDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGL 155

Query: 126 --------------------AMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLL 165
                               ++  P G S   G P G  G P  +     P E       
Sbjct: 156 GGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLP-GPPGAPGPQGFQGPPGEPG----- 209

Query: 166 EEGSAQP--------------DDGEDAPRPGRKETGTQTGGDGRGVSDAGAGVRGCRGCR 211
           E G++ P              DDGE A +PGR       G  G       AG+ G +G R
Sbjct: 210 EPGASGPMGPRGPPGPPGKNGDDGE-AGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHR 268

Query: 212 G-RGVGAAGGSVAGP 225
           G  G+  A G  AGP
Sbjct: 269 GFSGLDGAKGD-AGP 282



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 50/200 (25%), Positives = 64/200 (32%), Gaps = 35/200 (17%)

Query: 49  GRRAQRRPGPGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAPRG-------PTEPALR 101
           G R ++ P       G  G    P    +P E+  P  + +  P G       P E  ++
Sbjct: 629 GERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQ 688

Query: 102 RPSSADRPL----APGPSSSPGAGRAPGAMASPSGSSKATGKP--RGRDG--RPRREEDD 153
            P     P     APG   + G   APGA  S  G+    G P  RG  G   P+ +  D
Sbjct: 689 GPPGPAGPRGANGAPGNDGAKGDAGAPGAPGS-QGAPGLQGMPGERGAAGLPGPKGDRGD 747

Query: 154 VTPEEKRLRLLLEEGSAQPDDGEDAPR--------PGRKETGTQTGGDGRGVSDAGAGVR 205
             P+            A    G+D  R        PG        G  G        G R
Sbjct: 748 AGPK-----------GADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGAR 796

Query: 206 GCRGCRGRGVGAAGGSVAGP 225
           G  G RG          AGP
Sbjct: 797 GAPGDRGEPGPPGPAGFAGP 816



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 49/171 (28%), Positives = 58/171 (33%), Gaps = 31/171 (18%)

Query: 64  GASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPSSSPGAGRA 123
           G +G +  P S   P E   P  M    PRG        P    RP APGP+ + G   A
Sbjct: 281 GPAGPKGEPGS---PGENGAPGQM---GPRG-------LPGERGRPGAPGPAGARGNDGA 327

Query: 124 PGAMASPSGSSKATGKP--------RGRDGRPRREEDDVTPEEKRLRLLLEEGSAQPDDG 175
            GA A P G +   G P        +G  G P+       P+  R       G   P   
Sbjct: 328 TGA-AGPPGPTGPAGPPGFPGAVGAKGEAG-PQGPRGSEGPQGVR-------GEPGPPGP 378

Query: 176 EDAPRP-GRKETGTQTGGDGRGVSDAGAGVRGCRGCRGRGVGAAGGSVAGP 225
             A  P G      Q G  G   +   AG  G  G RG       G   GP
Sbjct: 379 AGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGP 429



 Score = 34.3 bits (77), Expect = 0.11
 Identities = 55/175 (31%), Positives = 62/175 (35%), Gaps = 21/175 (12%)

Query: 64  GASGQQRAPESNERPAEEPTP-----APMPSSAPRGPTEP--ALRRPSSADRPLAPGPSS 116
           GA G    P     PA  P P     AP    A RG   P  A   P +A R   PGPS 
Sbjct: 833 GAKGDA-GPPGPAGPAGPPGPIGNVGAPGAKGA-RGSAGPPGATGFPGAAGRVGPPGPSG 890

Query: 117 SPGAGRAPGAMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQPDDGE 176
           + G    PG    P+G     G PRG  G P     +V P         E+GS   D   
Sbjct: 891 NAGPPGPPG----PAGKEGGKG-PRGETG-PAGRPGEVGPPGPP-GPAGEKGSPGADGPA 943

Query: 177 DAP-RPGRKETGTQTGGDGRGVSDAGAGVRGCRGCRG----RGVGAAGGSVAGPG 226
            AP  PG +    Q G  G        G  G  G  G    +G   A G    PG
Sbjct: 944 GAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPG 998



 Score = 29.6 bits (65), Expect = 2.8
 Identities = 27/84 (32%), Positives = 31/84 (36%), Gaps = 12/84 (14%)

Query: 64   GASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPSSSPGAGRA 123
            G SG Q  P     P E+        + PRGP       P SA  P   G +  PG    
Sbjct: 1112 GFSGLQGPPGPPGSPGEQGPSGASGPAGPRGP-------PGSAGAPGKDGLNGLPGPIGP 1164

Query: 124  PGAMASPSGSSKATGKPRGRDGRP 147
            PG    P G +   G P G  G P
Sbjct: 1165 PG----PRGRTGDAG-PVGPPGPP 1183


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 48.9 bits (115), Expect = 4e-06
 Identities = 54/183 (29%), Positives = 69/183 (37%), Gaps = 24/183 (13%)

Query: 48  QGRRAQRRPGPGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSAD 107
           +G+R  R     V   G  G++ AP +   P  +  P P  +   RGP   +  + S  D
Sbjct: 500 EGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGD 559

Query: 108 RPLAPGPSSSPGAGRAPG--AMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLL 165
            P  PG    PGA    G   +  P G     G P G DGRP        P    +R   
Sbjct: 560 -PGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAP-GEDGRPG------PPGSIGIR--- 608

Query: 166 EEGSAQPDDGEDAPRPGRKETGTQTGGDGRGVSDAGAGVRGCRGCRGR-GVGAAGGSVAG 224
                QP        PG K +   +G  G+      AGV G RG  G+ G     G V  
Sbjct: 609 ----GQPG---SMGLPGPKGS---SGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGP 658

Query: 225 PGL 227
           PGL
Sbjct: 659 PGL 661



 Score = 41.6 bits (96), Expect = 7e-04
 Identities = 66/241 (27%), Positives = 77/241 (31%), Gaps = 40/241 (16%)

Query: 6   GRPFSPPWAGRPSGCNLVGAGRRCRAWPERAWPQAGDSDCLGQGRRAQRRPGPGVSAVGA 65
           G+P +P   G PS     G  R   A        AG  +  G G +    PG  V  VG 
Sbjct: 168 GQPGAPGPPGHPSHPGPDGLSRPFSA------QMAGLDEKSGLGSQVGLMPG-SVGPVGP 220

Query: 66  ------SGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPSSSPG 119
                  GQQ        P E   P PM     RGP  P          P  PG    PG
Sbjct: 221 RGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGP----------PGKPGEDGEPG 270

Query: 120 AGRAPGAMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQPDDGEDAP 179
               PG +   +GS  A G P G  G P  +        K L     E  A    GE  P
Sbjct: 271 RNGNPGEVGF-AGSPGARGFP-GAPGLPGLKGH---RGHKGLEGPKGEVGAPGSKGEAGP 325

Query: 180 RPGRKETGT-----QTGGDGRGVSDAGAGVRGCRGCRGR-------GVGAAGGSVAGPGL 227
                  G        G  GR       G RG  G  G+       G+  + G    PG+
Sbjct: 326 TGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGM 385

Query: 228 K 228
           K
Sbjct: 386 K 386



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 71/241 (29%), Positives = 87/241 (36%), Gaps = 61/241 (25%)

Query: 26  GRRCRAWPERAWPQAGDSDCLGQGRRAQRRPGPGVSAVGASGQQRAPESNERPAEE-PTP 84
           G R R  P+ A  Q G     G       +PGP +  +G  G    P +     E  PT 
Sbjct: 342 GERGRLGPQGAPGQRGAHGMPG-------KPGP-MGPLGIPGSSGFPGNPGMKGEAGPTG 393

Query: 85  APMPS--------SAPRGPT-EPALRRPSSAD-RPLAPGPSSSPGAGRAPGAMASPSGSS 134
           A  P         + P GP   P L      D  P A GP+ SPG    PG+ A P GS 
Sbjct: 394 ARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGS-AGPPGSP 452

Query: 135 KATGK--PRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQP--------------DDGEDA 178
              G   P+G  G+P    D   P  K        G A P                GE+ 
Sbjct: 453 GPQGSTGPQGIRGQP---GDPGVPGFK--------GEAGPKGEPGPHGIQGPIGPPGEEG 501

Query: 179 PRPGRKETGT-----------QTGGDGRGVSDAGAGVRGCRGCRGRGVGAAG--GSVAGP 225
            R  R + GT             G  G   SD   G +G +G RG  VG++G  GS   P
Sbjct: 502 KRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERG-PVGSSGPKGSQGDP 560

Query: 226 G 226
           G
Sbjct: 561 G 561



 Score = 36.6 bits (83), Expect = 0.023
 Identities = 55/205 (26%), Positives = 63/205 (30%), Gaps = 48/205 (23%)

Query: 49   GRRAQRRPGPGVSAVGASGQQRAPESNERPAE--------EPTPAPMPSS-APRGPTE-P 98
            G R +  P   V   G  G    P     P E         P P  +  S  P GP   P
Sbjct: 834  GSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVP 893

Query: 99   ALRR-------------PSSADRPLAPGPSSSPGAGRAPGAMASPSGSSKATGKP--RGR 143
             L+              P SA R   PGP+ +PG        A P G     G P  RG 
Sbjct: 894  GLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGP-------AGPLGEPGKEGPPGLRGD 946

Query: 144  DGRPRREEDDVTPEEKRLRLLLEEGSAQPDDGE-DAPRPGRKETGTQTGGDGRGVSDAGA 202
             G   R  D               G A P  G  D   PG        G  G   +    
Sbjct: 947  PGSHGRVGD--------------RGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQR 992

Query: 203  GVRGCRGCRG-RGVGAAGGSVAGPG 226
            G+ G  G RG RG+    G    PG
Sbjct: 993  GIVGMPGQRGERGMPGLPGPAGTPG 1017



 Score = 36.2 bits (82), Expect = 0.030
 Identities = 52/201 (25%), Positives = 64/201 (31%), Gaps = 37/201 (18%)

Query: 49  GRRAQRRPGPGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPT------------ 96
           G R ++ P       G  G    P    +P ++  P    +  P GP             
Sbjct: 663 GERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEP 722

Query: 97  -------EPALRRPSSADRPL-APGPSSSPGAGRAPGAMASPSGSSKATGKPRGRDGRPR 148
                  E  +      D P  +PGPS +PG    PG    P          RG  G P 
Sbjct: 723 GITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPG--------ERGIAGTPG 774

Query: 149 REEDDVTPEEKRLRLLLEEGSAQPDDGEDAPRP-GRKETGTQTGGDGRGVSDAGAGVRGC 207
            + D     EK       EG+A  D     P P G       TG  G        G  G 
Sbjct: 775 PKGDRGGIGEKG-----AEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGS 829

Query: 208 RGCRG-RGVGAAGGSV--AGP 225
           RG  G RG     G+V  AGP
Sbjct: 830 RGNPGSRGENGPTGAVGFAGP 850



 Score = 36.2 bits (82), Expect = 0.030
 Identities = 43/177 (24%), Positives = 52/177 (29%), Gaps = 30/177 (16%)

Query: 6    GRPFSPPWAGRPSGCNLVG----AGRRCRAWPERAWPQAGDSDCLGQGRRAQRRPGPGVS 61
            G P      G P     +G    AG+R    P+      GD      G R  R       
Sbjct: 1092 GAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGD-----HGDRGDRGQKGHRG 1146

Query: 62   AVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAP--------- 112
              G  G    P  N        P P     P GP  P+ +  +    PL P         
Sbjct: 1147 FTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPG--PLGPIGPPGVRGS 1204

Query: 113  ----GPSSSPGAGRAPGAMASPSGSSKATGKPRGR------DGRPRREEDDVTPEEK 159
                GP   PG    PG    P   + A G   G       D  P   ED   P++K
Sbjct: 1205 VGEAGPEGPPGEPGPPGPPGPPGHLTAALGDIMGHYDESMPDPLPEFTEDQAAPDDK 1261



 Score = 35.8 bits (81), Expect = 0.039
 Identities = 55/200 (27%), Positives = 69/200 (34%), Gaps = 29/200 (14%)

Query: 49   GRRAQRR----PGPG-----VSAVGASGQQR-----APESNERPAEEPTP-APMPSSAPR 93
            G+R +R     PGP      V   GA+G +       P  +  P  EP P  P  +    
Sbjct: 999  GQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTP 1058

Query: 94   GPTEPALRRPSSADRPLAPGPSSSPGAGRAPG--AMASPSGSSKATGKP--RGRDGRPRR 149
            G       R    D    PGP+  PG+  APG        G +   G P  RG  G P R
Sbjct: 1059 GRDGAVGERGDRGD----PGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGR 1114

Query: 150  EEDDVTPEEKRLRLLLEEGSAQPDDGEDAPRPGRKETGTQ--TGGDGRGVSDAGAGVRGC 207
                  P  +  R    +     D G+   +  R  TG Q   G  G       AG+ G 
Sbjct: 1115 AGKRGLPGPQGPR---GDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGP 1171

Query: 208  RGCRG-RGVGAAGGSVAGPG 226
             G RG  G     G    PG
Sbjct: 1172 FGPRGPPGPVGPSGKEGNPG 1191



 Score = 28.5 bits (62), Expect = 6.2
 Identities = 32/120 (26%), Positives = 45/120 (37%), Gaps = 15/120 (12%)

Query: 112 PGPSSSPGAG-----RAPGAMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLLE 166
           PGP+  PG+      R P     P G     G+P G  G+P        P          
Sbjct: 131 PGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEP-GVPGQPGAPGPPGHPSHPG-----P 184

Query: 167 EGSAQPDDGEDAPRPGRKETGTQTGGDGRGVSDAGAGVRGCRGCRGRGVGAAGGSVAGPG 226
           +G ++P   + A    +   G+Q G     V   G   RG +G +G+  GA  G    PG
Sbjct: 185 DGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGP--RGPQGLQGQQGGA--GPTGPPG 240


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score = 48.1 bits (113), Expect = 8e-06
 Identities = 54/180 (30%), Positives = 71/180 (39%), Gaps = 17/180 (9%)

Query: 56   PGPGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPS 115
            PGP     GA+GQ+       R      P    S  P GP  PA  R      P APGPS
Sbjct: 1364 PGPKGDP-GAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGER----GHPGAPGPS 1418

Query: 116  SSPGAGRAPGAMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQ---- 171
             SPG    PG+M       +   K   R    +  ++ +     R++  +E  +A     
Sbjct: 1419 GSPGLPGVPGSMGDMVNYDEI--KRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPG 1476

Query: 172  PDDGEDAP-RPGRKETGTQTGGDGRGVSDAGAGVRGCRGCRGR----GVGAAG-GSVAGP 225
            P   + AP RPG   +    G  GR       GVRG  G +G     G+G AG   + GP
Sbjct: 1477 PPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGP 1536



 Score = 35.8 bits (81), Expect = 0.039
 Identities = 50/177 (28%), Positives = 62/177 (35%), Gaps = 26/177 (14%)

Query: 6   GRPFSPPWAGRPSGCNLVGA----------GRRCRAWPERAWPQAGDSDCLGQ-GRRAQR 54
           G P +P   GRP      G           G  C A P         +   GQ G + ++
Sbjct: 691 GDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQ 750

Query: 55  RPGPGVSAVGASGQQRAPESNERPA-----EEPTPAPMPSSAPRG-PTEPALRRPSSADR 108
            P  GV   G  GQ   P     P       EP P       P+G P  P L        
Sbjct: 751 GP-EGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPG 809

Query: 109 PLAP-GPSSSPGAGRAPGAMAS-----PSGSSKATGKPRGRDGRPRREEDDVTPEEK 159
           P  P GP+   GA  +PG   +     P G+S     P GRDG+  +     TP EK
Sbjct: 810 PRGPPGPTGEKGAQGSPGVKGATGPVGPPGAS--VSGPPGRDGQQGQTGLRGTPGEK 864



 Score = 34.7 bits (78), Expect = 0.086
 Identities = 60/225 (26%), Positives = 77/225 (34%), Gaps = 35/225 (15%)

Query: 5   SGRPFSPPWAGRPSGCNLVGA-GRRCRAWPERAWPQAGDSDCLGQGRRAQRRPGPGVSAV 63
           +G P  PP    P+G  + GA G  C   P  +  Q GD   +     +  +  PG    
Sbjct: 610 AGSP-GPPGPVGPAG--IKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGF 666

Query: 64  GASGQQ-RAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPSSSPGAGR 122
           G  G+Q +A E   +  +     P     P G T     RP  +  P   GP+   G  +
Sbjct: 667 GLPGKQGKAGERGLKGQKGDAGNPGDPGTP-GTTG----RPGLSGEPGVQGPAGPKGE-K 720

Query: 123 APGAMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQPDDGEDAPRPG 182
             G  A PS     T    GR G+P                    G       E   RPG
Sbjct: 721 GDGCTACPSLQGTVTDMA-GRPGQP--------------------GPKGEQGPEGVGRPG 759

Query: 183 RKETGTQTGGDGRGVSDAGAGVRGCRGCRGRGVGAAGGSVAGPGL 227
           +     Q G  G        GV+G  G  GRGV    G    PGL
Sbjct: 760 KPG---QPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGL 801



 Score = 33.5 bits (75), Expect = 0.19
 Identities = 47/170 (27%), Positives = 58/170 (34%), Gaps = 8/170 (4%)

Query: 64   GASGQQRAPESNERPAEEPTPAPMPSSAPRGPT-EPALRRPSS-ADRPLAPGPSSSPGAG 121
            G  G+   P     P     P  M     +G T  P L  P     +P  PG +  PGA 
Sbjct: 1216 GLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAE 1275

Query: 122  RAPGAMASPSGSSKATGK--PRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQPDDGEDAP 179
              PGAM  P G     G   P G  G+P          +       E G A    G+  P
Sbjct: 1276 GEPGAM-GPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGL-PGQPGP 1333

Query: 180  RPGRKETGTQTGGDGRGVSDAGAGVRGCRGCRG-RGVGAAGGSVAGPGLK 228
             PG      + G DG    +   G +G  G  G +G   A G     G K
Sbjct: 1334 -PGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEK 1382



 Score = 31.6 bits (70), Expect = 0.73
 Identities = 49/187 (26%), Positives = 60/187 (32%), Gaps = 23/187 (12%)

Query: 48   QGRRAQRRPGPGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSAD 107
            +G  ++  PG     VG+ G    P    +  EE  P    S  P GP  P         
Sbjct: 1006 RGDNSEGDPG----CVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGP--------- 1052

Query: 108  RPLAPGPSSSPGAGRAPG--AMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLL 165
             P  PG   SPG     G   +   +G     G P G+ G P        P  K  R   
Sbjct: 1053 -PGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPP-GQPGYPGATGPPGLPGIKGERGYT 1110

Query: 166  ----EEGSAQPDDGEDAP-RPGRKETGTQTGGDGRGVSDAGAGVRGCRGCRG-RGVGAAG 219
                E+G   P   E  P  PG      + G  G        G +G  G  G  G     
Sbjct: 1111 GSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFP 1170

Query: 220  GSVAGPG 226
            G V  PG
Sbjct: 1171 GKVGSPG 1177



 Score = 30.0 bits (66), Expect = 2.1
 Identities = 58/215 (26%), Positives = 71/215 (33%), Gaps = 44/215 (20%)

Query: 39  QAGDSDCLGQGRRAQRRPGPG-VSAVGASGQQRAPE--SNERPAEEPTPAPMPSSAPRGP 95
           + GD    G   +  R   PG +  +G  GQ+  P     E  A EP P           
Sbjct: 403 EKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGP----------- 451

Query: 96  TEPALRRPSSADRPLAPGPSSSPGAGRAPGAMASPSGSSKATGK--PRGRDGRP--RREE 151
             P L  P     P  PG    P     PG      GSS   GK  P G+ G+P  + E+
Sbjct: 452 --PGLPGPPGIGLPGTPGDPGGP-----PGPKGD-KGSSGIPGKEGPGGKPGKPGVKGEK 503

Query: 152 DD-----VTPEEKRLRLLLEEGSAQPDDGEDAPRPGRKETGTQTGGDGRG------VSDA 200
            D      T  E     +   G   P      P P R + G Q     +G       S  
Sbjct: 504 GDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVV 563

Query: 201 GA-------GVRGCRGCRGRGVGAAGGSVAGPGLK 228
           GA       G  G  G  G G+    G    PGLK
Sbjct: 564 GAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLK 598



 Score = 28.1 bits (61), Expect = 8.1
 Identities = 41/164 (25%), Positives = 53/164 (32%), Gaps = 22/164 (13%)

Query: 58  PGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPSSS 117
           PG    G  G+   P             P  S  P GP  PA  + +  + P  P P+ S
Sbjct: 581 PGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGE-PCEPCPALS 639

Query: 118 ---PGAGRAPGAMASPSGSSKATGKPR-GRDGRPRREEDDVTPEEKRLRLLLEEGSAQPD 173
               G  R   A+  PSG     G P  G  G+  +  +     +K              
Sbjct: 640 NLQDGDVRVV-ALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQK-------------- 684

Query: 174 DGEDAPRPGRKETGTQTGGDGRGVSDAGAGVRGCRGCRGRGVGA 217
              DA  PG   T   TG  G        G  G +G +G G  A
Sbjct: 685 --GDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTA 726


>gi|11415052 retinoid X receptor, beta [Homo sapiens]
          Length = 533

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 57/229 (24%), Positives = 84/229 (36%), Gaps = 20/229 (8%)

Query: 20  CNLVGAGRRCRAWPERAWPQAGDSDCLGQGRRAQRRPGPGVSA---VGASGQQ-RAPESN 75
           C +    RR R W +   P A  +  +  G +    P PG +    +G SG+  R+P+S+
Sbjct: 30  CGVASRWRRRRPWLD---PAAAAAAAVAGGEQQTPEPEPGEAGRDGMGDSGRDSRSPDSS 86

Query: 76  ERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPSSSPGAGRAPGAMASPSGSSK 135
              +  P P  +P  +P GP  P    PS       P P   P    +P  + S S  S 
Sbjct: 87  ---SPNPLPQGVPPPSPPGPPLPPSTAPSLGGSGAPPPPPMPPPPLGSPFPVISSSMGSP 143

Query: 136 ATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQPDDGEDAPRPGRKETGTQTGGDGR 195
               P      P      V+  +    + L  G + P +    P  G +         G 
Sbjct: 144 GLPPP-----APPGFSGPVSSPQINSTVSLPGGGSGPPEDVKPPVLGVRGLHCPPPPGG- 197

Query: 196 GVSDAGAGVRGCRGCRGRGVGAAGGSVAGPGLKLVTERQLRRARSDSSR 244
                GAG R C  C  R  G   G  +  G K   +R +R+  + S R
Sbjct: 198 ----PGAGKRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCR 242


>gi|239753839 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 257

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 42/131 (32%), Positives = 56/131 (42%), Gaps = 14/131 (10%)

Query: 3   TLSGRPFSPPWAGRPSGCNLVGAGRRCRAWPERAWPQAGDSDCLGQGRRAQRRPGPGVSA 62
           T  G P     AG  +  +  G     R+ P R  P       LG G RA RRPG     
Sbjct: 124 TARGSPAGVERAGGATAASSAGT----RSVPARRLPPPCGGTSLGAGSRALRRPG----- 174

Query: 63  VGASGQQRAPESNERPAEEPTP-APMPSSAPRGPTEPALRRPSSADRPLAPGPSSSPGAG 121
             ++   R+P S+ R A  P P AP P +    P   A+  P +A   +AP P +  GA 
Sbjct: 175 --SAALPRSPSSSRRWAAMPGPGAPRPGAPGTWPVGFAVAAPPAAAASVAPPPPAVAGAP 232

Query: 122 RAP--GAMASP 130
            A   G +A+P
Sbjct: 233 AAAFRGWVAAP 243



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 41/136 (30%), Positives = 54/136 (39%), Gaps = 22/136 (16%)

Query: 27  RRCRAWPERAWPQAGDSDCLGQGRRA--QRRPGPGVSAVGASGQQRAPESNERPAEEPTP 84
           R  RA   RA P        G+GR A  +R P PG +    +G +RA  +    +     
Sbjct: 89  RASRAAGRRAGPAGPPCRAPGRGRAAATRRSPAPGTARGSPAGVERAGGATAASSAGTRS 148

Query: 85  APMPSSAPR------GPTEPALRRPSSADRPLAPGPS------SSPGAGR--APG----- 125
            P     P       G    ALRRP SA  P +P  S        PGA R  APG     
Sbjct: 149 VPARRLPPPCGGTSLGAGSRALRRPGSAALPRSPSSSRRWAAMPGPGAPRPGAPGTWPVG 208

Query: 126 -AMASPSGSSKATGKP 140
            A+A+P  ++ +   P
Sbjct: 209 FAVAAPPAAAASVAPP 224



 Score = 37.0 bits (84), Expect = 0.017
 Identities = 36/114 (31%), Positives = 46/114 (40%), Gaps = 17/114 (14%)

Query: 17  PSGCNLVGAGRRCRAWP-ERAWPQAGDSDCLGQGRRAQRRPGPGVSAVGASGQQRAPESN 75
           P G   +GAG R    P   A P++  S      RR    PGPG    GA G        
Sbjct: 157 PCGGTSLGAGSRALRRPGSAALPRSPSSS-----RRWAAMPGPGAPRPGAPGTW------ 205

Query: 76  ERPAEEPTPAPMPSSAPRGPTEPALR-RPSSADR--PLAPGPSSSPGAGRAPGA 126
             P      AP  ++A   P  PA+   P++A R    AP P  +PG   AP +
Sbjct: 206 --PVGFAVAAPPAAAASVAPPPPAVAGAPAAAFRGWVAAPDPGCTPGTENAPAS 257



 Score = 35.0 bits (79), Expect = 0.066
 Identities = 39/146 (26%), Positives = 53/146 (36%), Gaps = 23/146 (15%)

Query: 88  PSSAPRGPTEPALRRPSSA---DRPLAPGPSSSPGAGRAPGAMASPSGSSKATGKPRGRD 144
           P+ A RG + P +   +SA   + P A GP   P    A G    P+ +S+A G+  G  
Sbjct: 45  PAGARRGHSPPTVAPAASAGSQEHPGAGGPLCFPARSAAWG---PPARASRAAGRRAGPA 101

Query: 145 GRPRREEDDVTPEEKRLRLLLEEGSAQPDDGEDAPRPGRKETGTQTGGDGRGVSDAGAGV 204
           G P R          R R      S  P     +P       G +  G     S AG   
Sbjct: 102 GPPCRAPG-------RGRAAATRRSPAPGTARGSP------AGVERAGGATAASSAGTRS 148

Query: 205 RGCR----GCRGRGVGAAGGSVAGPG 226
              R     C G  +GA   ++  PG
Sbjct: 149 VPARRLPPPCGGTSLGAGSRALRRPG 174


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 52/186 (27%), Positives = 67/186 (36%), Gaps = 25/186 (13%)

Query: 53  QRRPGPGVSAVGASGQQRAPESNERPAEEPTP-APMPSSAPRGPTEPALRRPSSADRPLA 111
           Q  P P +       QQ+ P   + P ++P P  P P   P    +P      S+   +A
Sbjct: 53  QSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVA 112

Query: 112 PGPSSSPGAGRAPGAMAS-PSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSA 170
            GP  +PG G AP A +S P  +   +G P G    P       TP           G+ 
Sbjct: 113 QGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGP-------TPTPPPAVTSAPPGAP 165

Query: 171 QPDDGEDAPRPGRKETGTQTGG--------DGRGVS-DAGAGVRGCRGCRGRGVGAAGGS 221
            P      P  G   T  Q GG         G G     G G  G +G +  G    GG 
Sbjct: 166 PP----TPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGG- 220

Query: 222 VAGPGL 227
             GPGL
Sbjct: 221 --GPGL 224



 Score = 37.7 bits (86), Expect = 0.010
 Identities = 34/114 (29%), Positives = 41/114 (35%), Gaps = 11/114 (9%)

Query: 38  PQAGDSDCLGQGRRAQRRPGPGVSAVGASGQQRAPESNERPAEEPTPAPMP----SSAPR 93
           PQ      + QG       G    A  ++     P S   P   P P P P    +SAP 
Sbjct: 103 PQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPP 162

Query: 94  G---PTEPALRRPSSADRPLAPGPSSSPGA--GRAPGAMASPSGSSKATGKPRG 142
           G   PT P+   P++   P A GP   P A  G  PG    P       GK  G
Sbjct: 163 GAPPPTPPSSGVPTTP--PQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPG 214



 Score = 33.9 bits (76), Expect = 0.15
 Identities = 27/103 (26%), Positives = 33/103 (32%), Gaps = 10/103 (9%)

Query: 47  GQGRRAQRRPGPGVSAVGASGQQRAPESNERPAEEPT-------PAPMPSSAPRGPTEPA 99
           G G      P P V++         P S+  P   P        PA +P   P     P 
Sbjct: 144 GSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGPKQGPG 203

Query: 100 LRRPSSADRPLAPGPSSSPGAGRAPGAMASPSGSSKATGKPRG 142
              P     P  P P   PG    PG    P    +  G+PRG
Sbjct: 204 PGGPKGGKMPGGPKPGGGPGLS-TPG--GHPKPPHRGGGEPRG 243


>gi|19913396 smoothelin isoform b [Homo sapiens]
          Length = 915

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 50/169 (29%), Positives = 69/169 (40%), Gaps = 23/169 (13%)

Query: 64  GASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPSSSPGAGRA 123
           G S  +RA  +  RP +        S +   P +PA  R S+   PLA GPSS   AG  
Sbjct: 281 GPSDTKRADVAGPRPCQR-------SLSVLSPRQPAQNREST---PLASGPSSFQRAGSV 330

Query: 124 PGAMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQPDDGEDAPRPGR 183
              +   +  S      R +DG P+     +TP       L     A    G  +  P  
Sbjct: 331 RDRVHKFTSDSPMAA--RLQDGTPQAALSPLTPARLLGPSLTSTTPASSSSGSSSRGP-- 386

Query: 184 KETGTQTGGDGRGVSDAGAGVRGC---RGCRGRGVGA------AGGSVA 223
            +T ++   + RGV+   A +R C    G RGRG+ A      AGG VA
Sbjct: 387 SDTSSRFSKEQRGVAQPLAQLRSCPQEEGPRGRGLAARPLENRAGGPVA 435



 Score = 34.3 bits (77), Expect = 0.11
 Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 1/60 (1%)

Query: 72  PESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPSSSPGAGRAPGAMASPS 131
           P S       P+ +P P+S P  P EPA  +  +A+ P +P P  SP    +P    SP+
Sbjct: 195 PGSTSSSPASPSSSPTPAS-PEPPLEPAEAQCLTAEVPGSPEPPPSPPKTTSPEPQESPT 253



 Score = 32.3 bits (72), Expect = 0.43
 Identities = 22/85 (25%), Positives = 31/85 (36%), Gaps = 16/85 (18%)

Query: 69  QRAPESNERPAEEPTPAPMPSS-----------APRGPTEPALRRPSSADRPLAPGPSSS 117
           +R  +  +    +PTP P  +S           AP G T  +   PSS+  P +P P   
Sbjct: 160 EREEQEQQAEVSKPTPTPEGTSQDVTTVTLLLRAPPGSTSSSPASPSSSPTPASPEPPLE 219

Query: 118 PG-----AGRAPGAMASPSGSSKAT 137
           P          PG+   P    K T
Sbjct: 220 PAEAQCLTAEVPGSPEPPPSPPKTT 244



 Score = 29.6 bits (65), Expect = 2.8
 Identities = 30/121 (24%), Positives = 43/121 (35%), Gaps = 10/121 (8%)

Query: 56  PGPGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPS 115
           PG   S+  +      P S E P  EP  A   ++   G  EP    P S  +  +P P 
Sbjct: 195 PGSTSSSPASPSSSPTPASPEPPL-EPAEAQCLTAEVPGSPEP----PPSPPKTTSPEPQ 249

Query: 116 SSPGAGRAPG-----AMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSA 170
            SP      G      ++ P  +  A    RG     R +     P ++ L +L     A
Sbjct: 250 ESPTLPSTEGQVVNKLLSGPKETPAAQSPTRGPSDTKRADVAGPRPCQRSLSVLSPRQPA 309

Query: 171 Q 171
           Q
Sbjct: 310 Q 310


>gi|19913394 smoothelin isoform c [Homo sapiens]
          Length = 917

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 50/169 (29%), Positives = 69/169 (40%), Gaps = 23/169 (13%)

Query: 64  GASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPSSSPGAGRA 123
           G S  +RA  +  RP +        S +   P +PA  R S+   PLA GPSS   AG  
Sbjct: 281 GPSDTKRADVAGPRPCQR-------SLSVLSPRQPAQNREST---PLASGPSSFQRAGSV 330

Query: 124 PGAMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQPDDGEDAPRPGR 183
              +   +  S      R +DG P+     +TP       L     A    G  +  P  
Sbjct: 331 RDRVHKFTSDSPMAA--RLQDGTPQAALSPLTPARLLGPSLTSTTPASSSSGSSSRGP-- 386

Query: 184 KETGTQTGGDGRGVSDAGAGVRGC---RGCRGRGVGA------AGGSVA 223
            +T ++   + RGV+   A +R C    G RGRG+ A      AGG VA
Sbjct: 387 SDTSSRFSKEQRGVAQPLAQLRSCPQEEGPRGRGLAARPLENRAGGPVA 435



 Score = 34.3 bits (77), Expect = 0.11
 Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 1/60 (1%)

Query: 72  PESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPSSSPGAGRAPGAMASPS 131
           P S       P+ +P P+S P  P EPA  +  +A+ P +P P  SP    +P    SP+
Sbjct: 195 PGSTSSSPASPSSSPTPAS-PEPPLEPAEAQCLTAEVPGSPEPPPSPPKTTSPEPQESPT 253



 Score = 32.3 bits (72), Expect = 0.43
 Identities = 22/85 (25%), Positives = 31/85 (36%), Gaps = 16/85 (18%)

Query: 69  QRAPESNERPAEEPTPAPMPSS-----------APRGPTEPALRRPSSADRPLAPGPSSS 117
           +R  +  +    +PTP P  +S           AP G T  +   PSS+  P +P P   
Sbjct: 160 EREEQEQQAEVSKPTPTPEGTSQDVTTVTLLLRAPPGSTSSSPASPSSSPTPASPEPPLE 219

Query: 118 PG-----AGRAPGAMASPSGSSKAT 137
           P          PG+   P    K T
Sbjct: 220 PAEAQCLTAEVPGSPEPPPSPPKTT 244



 Score = 29.6 bits (65), Expect = 2.8
 Identities = 30/121 (24%), Positives = 43/121 (35%), Gaps = 10/121 (8%)

Query: 56  PGPGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPS 115
           PG   S+  +      P S E P  EP  A   ++   G  EP    P S  +  +P P 
Sbjct: 195 PGSTSSSPASPSSSPTPASPEPPL-EPAEAQCLTAEVPGSPEP----PPSPPKTTSPEPQ 249

Query: 116 SSPGAGRAPG-----AMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSA 170
            SP      G      ++ P  +  A    RG     R +     P ++ L +L     A
Sbjct: 250 ESPTLPSTEGQVVNKLLSGPKETPAAQSPTRGPSDTKRADVAGPRPCQRSLSVLSPRQPA 309

Query: 171 Q 171
           Q
Sbjct: 310 Q 310


>gi|19913398 smoothelin isoform a [Homo sapiens]
          Length = 940

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 51/169 (30%), Positives = 69/169 (40%), Gaps = 18/169 (10%)

Query: 65  ASGQQRAPESNERPAEEPTPAPMPSS-APRGPTEPALRRPSSADRPLAPGPSSSPGAGRA 123
           A    R P   +R A+   P P   S +   P +PA  R S+   PLA GPSS   AG  
Sbjct: 275 AQSPHRGPSDTKR-ADVAGPRPCQRSLSVLSPRQPAQNREST---PLASGPSSFQRAGSV 330

Query: 124 PGAMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQPDDGEDAPRPGR 183
              +   +  S      R +DG P+     +TP       L     A    G  +  P  
Sbjct: 331 RDRVHKFTSDSPMAA--RLQDGTPQAALSPLTPARLLGPSLTSTTPASSSSGSSSRGP-- 386

Query: 184 KETGTQTGGDGRGVSDAGAGVRGC---RGCRGRGVGA------AGGSVA 223
            +T ++   + RGV+   A +R C    G RGRG+ A      AGG VA
Sbjct: 387 SDTSSRFSKEQRGVAQPLAQLRSCPQEEGPRGRGLAARPLENRAGGPVA 435



 Score = 34.3 bits (77), Expect = 0.11
 Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 1/60 (1%)

Query: 72  PESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPSSSPGAGRAPGAMASPS 131
           P S       P+ +P P+S P  P EPA  +  +A+ P +P P  SP    +P    SP+
Sbjct: 195 PGSTSSSPASPSSSPTPAS-PEPPLEPAEAQCLTAEVPGSPEPPPSPPKTTSPEPQESPT 253



 Score = 32.3 bits (72), Expect = 0.43
 Identities = 22/85 (25%), Positives = 31/85 (36%), Gaps = 16/85 (18%)

Query: 69  QRAPESNERPAEEPTPAPMPSS-----------APRGPTEPALRRPSSADRPLAPGPSSS 117
           +R  +  +    +PTP P  +S           AP G T  +   PSS+  P +P P   
Sbjct: 160 EREEQEQQAEVSKPTPTPEGTSQDVTTVTLLLRAPPGSTSSSPASPSSSPTPASPEPPLE 219

Query: 118 PG-----AGRAPGAMASPSGSSKAT 137
           P          PG+   P    K T
Sbjct: 220 PAEAQCLTAEVPGSPEPPPSPPKTT 244


>gi|169204930 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 373

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 60/220 (27%), Positives = 73/220 (33%), Gaps = 40/220 (18%)

Query: 49  GRRAQRRPGPGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADR 108
           G R+  R  P        G   AP S  R    P    +  S PR PT        + D 
Sbjct: 44  GTRSSYRLLPQKGRGNLRGAPTAPVSFSRIRRNPLRTQLSGSPPRRPTSVLRLASPAGDL 103

Query: 109 PLAPGPSSSPG------------AGRAPGAMASPSGSSKATGKPRGRDGRPRREEDDVTP 156
           P  P P +  G             G   G +    G+ + +GK RG   RP+R       
Sbjct: 104 PRRPRPRAGGGRHSPRPAVGTIFRGGRKGRLREGRGAVRGSGKRRGWGLRPQR------- 156

Query: 157 EEKRLRLLLEEGSAQPDDGEDAPRPGRKETGTQTGGDGRGVSDAGAGVRGC-RGCRGRGV 215
              R RL    G   P  G  APR    +     G +  GV   G       RG  G   
Sbjct: 157 --VRSRL---AGLGAPRGGAAAPRGWGGQ-----GAERLGVHQPGLPTHAALRGGGGGSE 206

Query: 216 GAAGGSVAGPGLKLVTERQLRRARSDSSRRPPRRQLPLLG 255
           G  GG+   P           RAR   S RP  R+  LLG
Sbjct: 207 GGGGGARPSP----------PRARQPPSGRPRPRRTRLLG 236



 Score = 35.4 bits (80), Expect = 0.050
 Identities = 29/99 (29%), Positives = 37/99 (37%), Gaps = 2/99 (2%)

Query: 52  AQRRPGPGVSAVGASGQQRAPESNERPAEEPTP--APMPSSAPRGPTEPALRRPSSADRP 109
           A R  G G    G   +   P + + P+  P P    +  SA R     AL R     RP
Sbjct: 197 ALRGGGGGSEGGGGGARPSPPRARQPPSGRPRPRRTRLLGSAERHTGRAALARHGQLSRP 256

Query: 110 LAPGPSSSPGAGRAPGAMASPSGSSKATGKPRGRDGRPR 148
            A   +SS G G A    A+   +       R  DGR R
Sbjct: 257 HAAVRNSSRGRGAATSVSAAARPTRGGARGHRRADGRAR 295


>gi|239750393 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 373

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 60/220 (27%), Positives = 73/220 (33%), Gaps = 40/220 (18%)

Query: 49  GRRAQRRPGPGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADR 108
           G R+  R  P        G   AP S  R    P    +  S PR PT        + D 
Sbjct: 44  GTRSSYRLLPQKGRGNLRGAPTAPVSFSRIRRNPLRTQLSGSPPRRPTSVLRLASPAGDL 103

Query: 109 PLAPGPSSSPG------------AGRAPGAMASPSGSSKATGKPRGRDGRPRREEDDVTP 156
           P  P P +  G             G   G +    G+ + +GK RG   RP+R       
Sbjct: 104 PRRPRPRAGGGRHSPRPAVGTIFRGGRKGRLREGRGALRGSGKRRGWGLRPQR------- 156

Query: 157 EEKRLRLLLEEGSAQPDDGEDAPRPGRKETGTQTGGDGRGVSDAGAGVRGC-RGCRGRGV 215
              R RL    G   P  G  APR    +     G +  GV   G       RG  G   
Sbjct: 157 --VRSRL---AGLGAPRGGAAAPRGWGGQ-----GAERLGVHQPGLPTHAALRGGGGGSE 206

Query: 216 GAAGGSVAGPGLKLVTERQLRRARSDSSRRPPRRQLPLLG 255
           G  GG+   P           RAR   S RP  R+  LLG
Sbjct: 207 GGGGGARPSP----------PRARQPPSGRPRPRRTRLLG 236



 Score = 35.4 bits (80), Expect = 0.050
 Identities = 29/99 (29%), Positives = 37/99 (37%), Gaps = 2/99 (2%)

Query: 52  AQRRPGPGVSAVGASGQQRAPESNERPAEEPTP--APMPSSAPRGPTEPALRRPSSADRP 109
           A R  G G    G   +   P + + P+  P P    +  SA R     AL R     RP
Sbjct: 197 ALRGGGGGSEGGGGGARPSPPRARQPPSGRPRPRRTRLLGSAERHTGRAALARHGQLSRP 256

Query: 110 LAPGPSSSPGAGRAPGAMASPSGSSKATGKPRGRDGRPR 148
            A   +SS G G A    A+   +       R  DGR R
Sbjct: 257 HAAVRNSSRGRGAATSVSAAARPTRGGARGHRRADGRAR 295


>gi|239744694 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 373

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 60/220 (27%), Positives = 73/220 (33%), Gaps = 40/220 (18%)

Query: 49  GRRAQRRPGPGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADR 108
           G R+  R  P        G   AP S  R    P    +  S PR PT        + D 
Sbjct: 44  GTRSSYRLLPQKGRGNLRGAPTAPVSFSRIRRNPLRTQLSGSPPRRPTSVLRLASPAGDL 103

Query: 109 PLAPGPSSSPG------------AGRAPGAMASPSGSSKATGKPRGRDGRPRREEDDVTP 156
           P  P P +  G             G   G +    G+ + +GK RG   RP+R       
Sbjct: 104 PRRPRPRAGGGRHSPRPAVGTIFRGGRKGRLREGRGALRGSGKRRGWGLRPQR------- 156

Query: 157 EEKRLRLLLEEGSAQPDDGEDAPRPGRKETGTQTGGDGRGVSDAGAGVRGC-RGCRGRGV 215
              R RL    G   P  G  APR    +     G +  GV   G       RG  G   
Sbjct: 157 --VRSRL---AGLGAPRGGAAAPRGWGGQ-----GAERLGVHQPGLPTHAALRGGGGGSE 206

Query: 216 GAAGGSVAGPGLKLVTERQLRRARSDSSRRPPRRQLPLLG 255
           G  GG+   P           RAR   S RP  R+  LLG
Sbjct: 207 GGGGGARPSP----------PRARQPPSGRPRPRRTRLLG 236



 Score = 35.4 bits (80), Expect = 0.050
 Identities = 29/99 (29%), Positives = 37/99 (37%), Gaps = 2/99 (2%)

Query: 52  AQRRPGPGVSAVGASGQQRAPESNERPAEEPTP--APMPSSAPRGPTEPALRRPSSADRP 109
           A R  G G    G   +   P + + P+  P P    +  SA R     AL R     RP
Sbjct: 197 ALRGGGGGSEGGGGGARPSPPRARQPPSGRPRPRRTRLLGSAERHTGRAALARHGQLSRP 256

Query: 110 LAPGPSSSPGAGRAPGAMASPSGSSKATGKPRGRDGRPR 148
            A   +SS G G A    A+   +       R  DGR R
Sbjct: 257 HAAVRNSSRGRGAATSVSAAARPTRGGARGHRRADGRAR 295


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein
           [Homo sapiens]
          Length = 1650

 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 49/194 (25%), Positives = 64/194 (32%), Gaps = 20/194 (10%)

Query: 49  GRRAQRRPGPGVSAVGASGQQRAPESNERPAEEPTPAPMPSS---APRGPTEPALRRPSS 105
           G R QR P       GA G       +  P E   P P   +    P+GP  P    P  
Sbjct: 758 GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGP----PGK 813

Query: 106 ADRPLAPGPSSSPG-----AGRAPGAMASPSGSSKATGK--PRGRDGRPRREEDDVTPEE 158
              P  PG     G         P  +  P G++  TG    RG  G P    +   P  
Sbjct: 814 DGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGT 873

Query: 159 KRLRLLLEEGSAQPDDGEDAPR-----PGRKETGTQTGGDGRGVSDAGAGVRGCRGCRG- 212
                   +       G+D P      PG +      GG G   ++  +G  G  G  G 
Sbjct: 874 AGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGE 933

Query: 213 RGVGAAGGSVAGPG 226
           RG   +GG +  PG
Sbjct: 934 RGAAGSGGPIGPPG 947



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 57/202 (28%), Positives = 67/202 (33%), Gaps = 45/202 (22%)

Query: 64   GASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLA------------ 111
            G  G Q  P  +    E     PM    P GP  PA   P+ AD P              
Sbjct: 1067 GPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPA--GPNGADGPQGPPGGVGNLGPPG 1124

Query: 112  ----PGPSSSPGAGRAPGAMA-----------------SPSGSSKATGK--PRGRDGRPR 148
                PG S SPG    PG                     P G    TG   P+G  G   
Sbjct: 1125 EKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVG 1184

Query: 149  REEDDVTPEEKRLRLLLEEGSAQPDDGEDAPRPGRKETGTQTGGDGRGVSDAGAGVRGCR 208
               D   P E   R    +  A+ D GED   PG+  +   TG +G        G  G  
Sbjct: 1185 FPGDPGPPGEGGPR---GQDGAKGDRGEDG-EPGQPGSPGPTGENGPPGPLGKRGPAGSP 1240

Query: 209  GCRGR--GVGAAG--GSVAGPG 226
            G  GR  G GA G  G++  PG
Sbjct: 1241 GSEGRQGGKGAKGDPGAIGAPG 1262



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 55/218 (25%), Positives = 72/218 (33%), Gaps = 23/218 (10%)

Query: 49  GRRAQRRPGPGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADR 108
           G R    P     ++G  G+   P     P  +  P P  +  P G   P   +P     
Sbjct: 539 GVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQ-GKPGLPGM 597

Query: 109 PLAPGPSSSPGAGRAPGAMAS--PSGSSKATGKP-----------RGRDGRPRREEDDVT 155
           P + GP   PG    PG   +  PSG     G P           RG  G    + +D  
Sbjct: 598 PGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGF 657

Query: 156 PEEK---RLRLLLEEGSAQPDDGEDAPRPGRKETGT--QTGGDGRGVSDAGAGVRGCRGC 210
           P  K    ++    E       GED P   +  TG     G  G        GV G  G 
Sbjct: 658 PGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGY 717

Query: 211 RGRGVGAAGGSVAGPGLKLVTERQLRRARSDSSRRPPR 248
            GR      GS+  PG    +    + AR  S +  PR
Sbjct: 718 PGR--QGPKGSLGFPGFPGASGE--KGARGLSGKSGPR 751



 Score = 32.0 bits (71), Expect = 0.56
 Identities = 46/183 (25%), Positives = 61/183 (33%), Gaps = 41/183 (22%)

Query: 58  PGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPS-- 115
           PG+   G  G +        P  +  P P+     RGP   A   P S   P  PG S  
Sbjct: 307 PGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRA-GLPGSDGAPGPPGTSLM 365

Query: 116 -----SSPGAGRAPG-----------------AMASPSGSSKATGKPR--GRDGRP--RR 149
                 S G  + P                  A+  P G    TG+P   G+ G P  + 
Sbjct: 366 LPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKG 425

Query: 150 EEDDVTPEEKRLRLLLEEGSAQPDDGEDAPRPGRKETGTQTGGDGRGVSDAGAGVRGCRG 209
           E  D+ P+  R      +G   P        PG+     + G DG        GV+G RG
Sbjct: 426 ESGDLGPQGPRG----PQGLTGP--------PGKAGRRGRAGADGARGMPGDPGVKGDRG 473

Query: 210 CRG 212
             G
Sbjct: 474 FDG 476


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein
           [Homo sapiens]
          Length = 1629

 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 49/194 (25%), Positives = 64/194 (32%), Gaps = 20/194 (10%)

Query: 49  GRRAQRRPGPGVSAVGASGQQRAPESNERPAEEPTPAPMPSS---APRGPTEPALRRPSS 105
           G R QR P       GA G       +  P E   P P   +    P+GP  P    P  
Sbjct: 737 GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGP----PGK 792

Query: 106 ADRPLAPGPSSSPG-----AGRAPGAMASPSGSSKATGK--PRGRDGRPRREEDDVTPEE 158
              P  PG     G         P  +  P G++  TG    RG  G P    +   P  
Sbjct: 793 DGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGT 852

Query: 159 KRLRLLLEEGSAQPDDGEDAPR-----PGRKETGTQTGGDGRGVSDAGAGVRGCRGCRG- 212
                   +       G+D P      PG +      GG G   ++  +G  G  G  G 
Sbjct: 853 AGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGE 912

Query: 213 RGVGAAGGSVAGPG 226
           RG   +GG +  PG
Sbjct: 913 RGAAGSGGPIGPPG 926



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 57/202 (28%), Positives = 67/202 (33%), Gaps = 45/202 (22%)

Query: 64   GASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLA------------ 111
            G  G Q  P  +    E     PM    P GP  PA   P+ AD P              
Sbjct: 1046 GPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPA--GPNGADGPQGPPGGVGNLGPPG 1103

Query: 112  ----PGPSSSPGAGRAPGAMA-----------------SPSGSSKATGK--PRGRDGRPR 148
                PG S SPG    PG                     P G    TG   P+G  G   
Sbjct: 1104 EKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVG 1163

Query: 149  REEDDVTPEEKRLRLLLEEGSAQPDDGEDAPRPGRKETGTQTGGDGRGVSDAGAGVRGCR 208
               D   P E   R    +  A+ D GED   PG+  +   TG +G        G  G  
Sbjct: 1164 FPGDPGPPGEGGPR---GQDGAKGDRGEDG-EPGQPGSPGPTGENGPPGPLGKRGPAGSP 1219

Query: 209  GCRGR--GVGAAG--GSVAGPG 226
            G  GR  G GA G  G++  PG
Sbjct: 1220 GSEGRQGGKGAKGDPGAIGAPG 1241



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 55/218 (25%), Positives = 72/218 (33%), Gaps = 23/218 (10%)

Query: 49  GRRAQRRPGPGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADR 108
           G R    P     ++G  G+   P     P  +  P P  +  P G   P   +P     
Sbjct: 518 GVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQ-GKPGLPGM 576

Query: 109 PLAPGPSSSPGAGRAPGAMAS--PSGSSKATGKP-----------RGRDGRPRREEDDVT 155
           P + GP   PG    PG   +  PSG     G P           RG  G    + +D  
Sbjct: 577 PGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGF 636

Query: 156 PEEK---RLRLLLEEGSAQPDDGEDAPRPGRKETGT--QTGGDGRGVSDAGAGVRGCRGC 210
           P  K    ++    E       GED P   +  TG     G  G        GV G  G 
Sbjct: 637 PGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGY 696

Query: 211 RGRGVGAAGGSVAGPGLKLVTERQLRRARSDSSRRPPR 248
            GR      GS+  PG    +    + AR  S +  PR
Sbjct: 697 PGR--QGPKGSLGFPGFPGASGE--KGARGLSGKSGPR 730



 Score = 32.0 bits (71), Expect = 0.56
 Identities = 46/183 (25%), Positives = 61/183 (33%), Gaps = 41/183 (22%)

Query: 58  PGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPS-- 115
           PG+   G  G +        P  +  P P+     RGP   A   P S   P  PG S  
Sbjct: 286 PGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRA-GLPGSDGAPGPPGTSLM 344

Query: 116 -----SSPGAGRAPG-----------------AMASPSGSSKATGKPR--GRDGRP--RR 149
                 S G  + P                  A+  P G    TG+P   G+ G P  + 
Sbjct: 345 LPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKG 404

Query: 150 EEDDVTPEEKRLRLLLEEGSAQPDDGEDAPRPGRKETGTQTGGDGRGVSDAGAGVRGCRG 209
           E  D+ P+  R      +G   P        PG+     + G DG        GV+G RG
Sbjct: 405 ESGDLGPQGPRG----PQGLTGP--------PGKAGRRGRAGADGARGMPGDPGVKGDRG 452

Query: 210 CRG 212
             G
Sbjct: 453 FDG 455


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 49/194 (25%), Positives = 64/194 (32%), Gaps = 20/194 (10%)

Query: 49   GRRAQRRPGPGVSAVGASGQQRAPESNERPAEEPTPAPMPSS---APRGPTEPALRRPSS 105
            G R QR P       GA G       +  P E   P P   +    P+GP  P    P  
Sbjct: 844  GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGP----PGK 899

Query: 106  ADRPLAPGPSSSPG-----AGRAPGAMASPSGSSKATGK--PRGRDGRPRREEDDVTPEE 158
               P  PG     G         P  +  P G++  TG    RG  G P    +   P  
Sbjct: 900  DGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGT 959

Query: 159  KRLRLLLEEGSAQPDDGEDAPR-----PGRKETGTQTGGDGRGVSDAGAGVRGCRGCRG- 212
                    +       G+D P      PG +      GG G   ++  +G  G  G  G 
Sbjct: 960  AGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGE 1019

Query: 213  RGVGAAGGSVAGPG 226
            RG   +GG +  PG
Sbjct: 1020 RGAAGSGGPIGPPG 1033



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 57/202 (28%), Positives = 67/202 (33%), Gaps = 45/202 (22%)

Query: 64   GASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLA------------ 111
            G  G Q  P  +    E     PM    P GP  PA   P+ AD P              
Sbjct: 1153 GPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPA--GPNGADGPQGPPGGVGNLGPPG 1210

Query: 112  ----PGPSSSPGAGRAPGAMA-----------------SPSGSSKATGK--PRGRDGRPR 148
                PG S SPG    PG                     P G    TG   P+G  G   
Sbjct: 1211 EKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVG 1270

Query: 149  REEDDVTPEEKRLRLLLEEGSAQPDDGEDAPRPGRKETGTQTGGDGRGVSDAGAGVRGCR 208
               D   P E   R    +  A+ D GED   PG+  +   TG +G        G  G  
Sbjct: 1271 FPGDPGPPGEGGPR---GQDGAKGDRGEDG-EPGQPGSPGPTGENGPPGPLGKRGPAGSP 1326

Query: 209  GCRGR--GVGAAG--GSVAGPG 226
            G  GR  G GA G  G++  PG
Sbjct: 1327 GSEGRQGGKGAKGDPGAIGAPG 1348



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 55/218 (25%), Positives = 72/218 (33%), Gaps = 23/218 (10%)

Query: 49  GRRAQRRPGPGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADR 108
           G R    P     ++G  G+   P     P  +  P P  +  P G   P   +P     
Sbjct: 625 GVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQ-GKPGLPGM 683

Query: 109 PLAPGPSSSPGAGRAPGAMAS--PSGSSKATGKP-----------RGRDGRPRREEDDVT 155
           P + GP   PG    PG   +  PSG     G P           RG  G    + +D  
Sbjct: 684 PGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGF 743

Query: 156 PEEK---RLRLLLEEGSAQPDDGEDAPRPGRKETGT--QTGGDGRGVSDAGAGVRGCRGC 210
           P  K    ++    E       GED P   +  TG     G  G        GV G  G 
Sbjct: 744 PGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGY 803

Query: 211 RGRGVGAAGGSVAGPGLKLVTERQLRRARSDSSRRPPR 248
            GR      GS+  PG    +    + AR  S +  PR
Sbjct: 804 PGR--QGPKGSLGFPGFPGASGE--KGARGLSGKSGPR 837



 Score = 32.0 bits (71), Expect = 0.56
 Identities = 46/183 (25%), Positives = 61/183 (33%), Gaps = 41/183 (22%)

Query: 58  PGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPS-- 115
           PG+   G  G +        P  +  P P+     RGP   A   P S   P  PG S  
Sbjct: 393 PGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRA-GLPGSDGAPGPPGTSLM 451

Query: 116 -----SSPGAGRAPG-----------------AMASPSGSSKATGKPR--GRDGRP--RR 149
                 S G  + P                  A+  P G    TG+P   G+ G P  + 
Sbjct: 452 LPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKG 511

Query: 150 EEDDVTPEEKRLRLLLEEGSAQPDDGEDAPRPGRKETGTQTGGDGRGVSDAGAGVRGCRG 209
           E  D+ P+  R      +G   P        PG+     + G DG        GV+G RG
Sbjct: 512 ESGDLGPQGPRG----PQGLTGP--------PGKAGRRGRAGADGARGMPGDPGVKGDRG 559

Query: 210 CRG 212
             G
Sbjct: 560 FDG 562


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 59/208 (28%), Positives = 74/208 (35%), Gaps = 26/208 (12%)

Query: 8   PFSPPWAGRPSGCNLVGAGRRCRAWPERAWPQAGDSDCLGQGRRAQRRPGPGVSAVGASG 67
           P S    GR +G    GAGRR R    R   +   S      RR +RRP P      +  
Sbjct: 370 PSSQGRGGRAAG----GAGRRRR---RRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRS 422

Query: 68  QQRAPESNE----RPAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPSSSPGAGRA 123
             RA  S++    R A  P P P       G  + A  RP  A RP +  P  SPG   A
Sbjct: 423 LSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRA-RPASTSP--SPG---A 476

Query: 124 PGAMASPSGSSKATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQPDDGEDAPRPGR 183
            G    P G S +    R     PR      +P + R R        +P     +P P +
Sbjct: 477 HGRRGGPEGKSSS----RSPGPHPRSWSSSRSPSKSRSR----SAEKRPHSPSRSPSP-K 527

Query: 184 KETGTQTGGDGRGVSDAGAGVRGCRGCR 211
           K       G+GR         R  R  R
Sbjct: 528 KPLSRDKDGEGRARHSEAEATRARRRSR 555



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 53/218 (24%), Positives = 74/218 (33%), Gaps = 22/218 (10%)

Query: 33  PERAWPQAGDSDCLGQGRRAQ--RRPGPGVSAVGASGQQRAPESNERPAE--EPTPAPMP 88
           P R  P+  D       +R+   R P P   +   S Q+         A    P  A  P
Sbjct: 275 PSRLSPKHRDEGRKTGSQRSSGSRSPSPSGGSGWGSPQRNGGSGQRSGAHGGRPGSAHSP 334

Query: 89  SSAPRGPTEPALRRPSSADRPLAPGPSSSPGAGRAPGAMASPSGSSKATGKPRGRDGRPR 148
              P  P+      P   D+  A  P+       +P   ++PS   +  G+  G  GR R
Sbjct: 335 PDKPSSPS------PRVRDKAAAAAPTPPARGKESPSPRSAPSSQGRG-GRAAGGAGRRR 387

Query: 149 REEDDVTPEEKRLRLLLEEGSAQPDDGEDAPRPGRKETGTQTGGDGRGVSDAGAGVRGCR 208
           R         +R R      SA    G   PRP      +++    R  SD+G+G    R
Sbjct: 388 R-------RRRRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSG----R 436

Query: 209 GCRGRGVGAAGGSVAGPGLKLVTERQLRRARSDSSRRP 246
           G  G G         G   K   ER  R   + +S  P
Sbjct: 437 GAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSP 474


>gi|48255931 hepatoma-derived growth factor-related protein 2
           isoform 1 [Homo sapiens]
          Length = 671

 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 57/221 (25%), Positives = 85/221 (38%), Gaps = 31/221 (14%)

Query: 38  PQAGDSDCLGQGRRAQRRPGPGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTE 97
           P A DSD       A  +P P   A  AS    +  S++       P       PRG   
Sbjct: 229 PSASDSDSKADSDGA--KPEPVAMARSASSSSSSSSSSDSDVSVKKP-------PRG--- 276

Query: 98  PALRRPSSADRPLAPGPSSSPGAGRAPGAMASPSGSS--------KATGKPRGRDGRPRR 149
              R+P  A++PL       P   R P + +S S S         K   + R R+   RR
Sbjct: 277 ---RKP--AEKPLPKPRGRKPKPERPPSSSSSDSDSDEVDRISEWKRRDEARRRELEARR 331

Query: 150 EEDDVTPEEKRLRLLLEEGSAQPDDGEDAPRPGRKETGTQTGGDGRGVSDAGAGVRGCRG 209
             +    +E+ LR L E+   + +   +    G  E G+  G  G  + +    V+  RG
Sbjct: 332 RRE----QEEELRRLREQEKEEKERRRERADRGEAERGSG-GSSGDELREDDEPVKK-RG 385

Query: 210 CRGRGVGAAGGSVAGPGLKLVTERQLRRARSDSSRRPPRRQ 250
            +GRG G    S + P  +L  E +    +  SS   P R+
Sbjct: 386 RKGRGRGPPSSSDSEPEAELEREAKKSAKKPQSSSTEPARK 426


>gi|14249158 hepatoma-derived growth factor-related protein 2
           isoform 2 [Homo sapiens]
          Length = 670

 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 57/221 (25%), Positives = 85/221 (38%), Gaps = 31/221 (14%)

Query: 38  PQAGDSDCLGQGRRAQRRPGPGVSAVGASGQQRAPESNERPAEEPTPAPMPSSAPRGPTE 97
           P A DSD       A  +P P   A  AS    +  S++       P       PRG   
Sbjct: 229 PSASDSDSKADSDGA--KPEPVAMARSASSSSSSSSSSDSDVSVKKP-------PRG--- 276

Query: 98  PALRRPSSADRPLAPGPSSSPGAGRAPGAMASPSGSS--------KATGKPRGRDGRPRR 149
              R+P  A++PL       P   R P + +S S S         K   + R R+   RR
Sbjct: 277 ---RKP--AEKPLPKPRGRKPKPERPPSSSSSDSDSDEVDRISEWKRRDEARRRELEARR 331

Query: 150 EEDDVTPEEKRLRLLLEEGSAQPDDGEDAPRPGRKETGTQTGGDGRGVSDAGAGVRGCRG 209
             +    +E+ LR L E+   + +   +    G  E G+  G  G  + +    V+  RG
Sbjct: 332 RRE----QEEELRRLREQEKEEKERRRERADRGEAERGSG-GSSGDELREDDEPVKK-RG 385

Query: 210 CRGRGVGAAGGSVAGPGLKLVTERQLRRARSDSSRRPPRRQ 250
            +GRG G    S + P  +L  E +    +  SS   P R+
Sbjct: 386 RKGRGRGPPSSSDSEPEAELEREAKKSAKKPQSSSTEPARK 426


>gi|239754081 PREDICTED: hypothetical protein XP_002345876 [Homo
           sapiens]
          Length = 355

 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 63/223 (28%), Positives = 82/223 (36%), Gaps = 26/223 (11%)

Query: 53  QRRPGPGVSAVGASGQQRAPESNERPAEEPTPAPM------PSSAPRGPTEPALRRPSSA 106
           Q +       +G+SG  R P S   P   P P P       P+S+PR P        +  
Sbjct: 56  QSKQKADTETIGSSGGSRGP-SPAHPWTTPQPGPPHQPGFNPASSPRLPLPADSEPDAYT 114

Query: 107 DRPLAPGPSSSPGAG--RAPGAMASPSGSSKATGKPRGRDGRPRREED---DVTPEEKRL 161
             P   GP+   GAG  RA G +   + +  ++  PR R    RR         PE +  
Sbjct: 115 SAPRGSGPTYCAGAGNSRAGGGLTKYNSAHSSSRVPRPRLPSQRRGASCGLGPGPESRAA 174

Query: 162 RLLLEEGSAQPDDGED-----APRPGRKETGTQTGGDGRG------VSDAGAGVRG-CRG 209
           R  L   SA+            P PG   TG +  G   G       +  G+  RG  R 
Sbjct: 175 RQGLGGRSARARTRRGPHRTRRPEPGPHHTGARQAGPLPGTRGRTRAAGTGSAARGPARH 234

Query: 210 CRGRGVGAAGGSVAGPGLKLVTERQLRRARSDSSRRPPRRQLP 252
            RG  V AA  +    GL      +L   RS S  RPP R  P
Sbjct: 235 LRGGSVAAAAAARC-LGLSPPGRSRLFSPRS-SLARPPLRFPP 275


>gi|239749251 PREDICTED: similar to hCG2042508 [Homo sapiens]
          Length = 460

 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 57/194 (29%), Positives = 69/194 (35%), Gaps = 38/194 (19%)

Query: 78  PAEEPTPAPMPSSAPRGPTEPALRRPSSADRPLAPGPSSSPGAGRA-------PGAMASP 130
           P E   PAP P     GPT P  R P+   R    G + S G+G A       PG   SP
Sbjct: 201 PQETAAPAPQP-----GPTAPPARPPAYESREGPRGRAESRGSGPAQPAHLPLPGPAHSP 255

Query: 131 SGSS------KATGKPRGRDGRPRREEDDVTPEEKRLRLLLEEGSAQPDDGEDAPRPGRK 184
           +  +      +A G   GR  RPR  E     E     + L  G        D  R G  
Sbjct: 256 APPAPELREGRAPGSTAGR--RPRPREPQAAEESGCATVGLRRG--------DCDRAGSS 305

Query: 185 ETGTQTGGDGRGVSDAGAGVRGCRGCRGRGVGAAGGSVAGPGLK---LVTERQLRRARSD 241
           +    T G+G          R   G  G G  A  G  + PG +    V    LR    +
Sbjct: 306 QP-PATSGNGERCRFCRRRRRRGGGGEGEGTHATHGPASPPGRRHDEEVGAAVLRAGSGE 364

Query: 242 SSRR------PPRR 249
            SRR      PPRR
Sbjct: 365 GSRRGLQLTPPPRR 378


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.132    0.409 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,161,205
Number of Sequences: 37866
Number of extensions: 1123586
Number of successful extensions: 17663
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 546
Number of HSP's successfully gapped in prelim test: 1875
Number of HSP's that attempted gapping in prelim test: 8975
Number of HSP's gapped (non-prelim): 7770
length of query: 261
length of database: 18,247,518
effective HSP length: 100
effective length of query: 161
effective length of database: 14,460,918
effective search space: 2328207798
effective search space used: 2328207798
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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