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Search of human proteins with 239755070
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239755070 PREDICTED: similar to proprotein convertase
subtilisin/kexin type 5 [Homo sapiens]
(853 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239755070 PREDICTED: similar to proprotein convertase subtili... 1922 0.0
gi|239749596 PREDICTED: hypothetical protein XP_002347099 [Homo ... 1911 0.0
gi|239743863 PREDICTED: hypothetical protein XP_002342982 [Homo ... 1909 0.0
gi|108773804 Fraser syndrome 1 [Homo sapiens] 315 1e-85
gi|20336246 proprotein convertase subtilisin/kexin type 5 prepro... 156 7e-38
gi|4505577 paired basic amino acid cleaving system 4 isoform a p... 141 3e-33
gi|20336180 paired basic amino acid cleaving system 4 isoform b ... 141 3e-33
gi|20336184 paired basic amino acid cleaving system 4 isoform h ... 137 3e-32
gi|20336182 paired basic amino acid cleaving system 4 isoform g ... 137 6e-32
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 130 4e-30
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 115 1e-25
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 110 4e-24
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 109 9e-24
gi|33598931 scavenger receptor class F, member 1 isoform 3 precu... 89 2e-17
gi|33598929 scavenger receptor class F, member 1 isoform 1 precu... 89 2e-17
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 78 3e-14
gi|143770880 laminin, beta 4 [Homo sapiens] 78 3e-14
gi|205360958 cysteine-rich with EGF-like domains 2 isoform b [Ho... 76 2e-13
gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo... 74 7e-13
gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo... 74 7e-13
gi|145309306 scavenger receptor class F, member 1 isoform 5 prec... 67 5e-11
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 67 5e-11
gi|84490388 R-spondin1 [Homo sapiens] 66 2e-10
gi|51873053 fibulin 2 isoform a precursor [Homo sapiens] 66 2e-10
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 65 3e-10
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 65 3e-10
gi|110825958 v-erb-a erythroblastic leukemia viral oncogene homo... 65 3e-10
gi|4885215 v-erb-a erythroblastic leukemia viral oncogene homolo... 65 3e-10
gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 64 6e-10
gi|29725609 epidermal growth factor receptor isoform a precursor... 63 1e-09
>gi|239755070 PREDICTED: similar to proprotein convertase
subtilisin/kexin type 5 [Homo sapiens]
Length = 853
Score = 1922 bits (4979), Expect = 0.0
Identities = 853/853 (100%), Positives = 853/853 (100%)
Query: 1 MKWILGKNNCADFEGVPQMMLTSIGKILGIGQSNVVTREGDPPVQKQIHLKCGNRFDHHC 60
MKWILGKNNCADFEGVPQMMLTSIGKILGIGQSNVVTREGDPPVQKQIHLKCGNRFDHHC
Sbjct: 1 MKWILGKNNCADFEGVPQMMLTSIGKILGIGQSNVVTREGDPPVQKQIHLKCGNRFDHHC 60
Query: 61 YKTCPEKTYSEAVECKACDSNCSSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGE 120
YKTCPEKTYSEAVECKACDSNCSSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGE
Sbjct: 61 YKTCPEKTYSEAVECKACDSNCSSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGE 120
Query: 121 CESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSC 180
CESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSC
Sbjct: 121 CESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSC 180
Query: 181 KTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKKC 240
KTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKKC
Sbjct: 181 KTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKKC 240
Query: 241 QMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEGGHVLHHGV 300
QMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEGGHVLHHGV
Sbjct: 241 QMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEGGHVLHHGV 300
Query: 301 CQENCPERHVAVEGVCKHCPEMCQDCIHEKTCKECMPEFFLHDDMCHQSCPRGFYADSHH 360
CQENCPERHVAVEGVCKHCPEMCQDCIHEKTCKECMPEFFLHDDMCHQSCPRGFYADSHH
Sbjct: 301 CQENCPERHVAVEGVCKHCPEMCQDCIHEKTCKECMPEFFLHDDMCHQSCPRGFYADSHH 360
Query: 361 CVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKQTKECRDCHKSCLT 420
CVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKQTKECRDCHKSCLT
Sbjct: 361 CVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKQTKECRDCHKSCLT 420
Query: 421 CSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQ 480
CSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQ
Sbjct: 421 CSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQ 480
Query: 481 TCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGK 540
TCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGK
Sbjct: 481 TCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGK 540
Query: 541 ECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDH 600
ECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDH
Sbjct: 541 ECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDH 600
Query: 601 YYVEQSTQTCERCHPTCDQCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFN 660
YYVEQSTQTCERCHPTCDQCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFN
Sbjct: 601 YYVEQSTQTCERCHPTCDQCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFN 660
Query: 661 CEKCHESCMECKGPGAKNCTLCPANLVLHMDESHCLHCCNTSDPPSAQECCDCQDTTDEC 720
CEKCHESCMECKGPGAKNCTLCPANLVLHMDESHCLHCCNTSDPPSAQECCDCQDTTDEC
Sbjct: 661 CEKCHESCMECKGPGAKNCTLCPANLVLHMDESHCLHCCNTSDPPSAQECCDCQDTTDEC 720
Query: 721 ILRTSKVRPATEHFKTALFITSSMMLVLLLGAAVVVWKKSRGRVQPAAKAGYEKLADPNK 780
ILRTSKVRPATEHFKTALFITSSMMLVLLLGAAVVVWKKSRGRVQPAAKAGYEKLADPNK
Sbjct: 721 ILRTSKVRPATEHFKTALFITSSMMLVLLLGAAVVVWKKSRGRVQPAAKAGYEKLADPNK 780
Query: 781 SYSSYKSSYRESTSFEEDQVIEYRDRDYDEDDDDDIVYMGQDGTVYRKFKYGLLDDDDID 840
SYSSYKSSYRESTSFEEDQVIEYRDRDYDEDDDDDIVYMGQDGTVYRKFKYGLLDDDDID
Sbjct: 781 SYSSYKSSYRESTSFEEDQVIEYRDRDYDEDDDDDIVYMGQDGTVYRKFKYGLLDDDDID 840
Query: 841 ELEYDDESYSYYQ 853
ELEYDDESYSYYQ
Sbjct: 841 ELEYDDESYSYYQ 853
>gi|239749596 PREDICTED: hypothetical protein XP_002347099 [Homo
sapiens]
Length = 853
Score = 1911 bits (4951), Expect = 0.0
Identities = 847/853 (99%), Positives = 850/853 (99%)
Query: 1 MKWILGKNNCADFEGVPQMMLTSIGKILGIGQSNVVTREGDPPVQKQIHLKCGNRFDHHC 60
MKWILGKNNCADFEGVPQMMLTSIGKILGIGQSNVVTREGDPPVQKQIHLKCGNRFDHHC
Sbjct: 1 MKWILGKNNCADFEGVPQMMLTSIGKILGIGQSNVVTREGDPPVQKQIHLKCGNRFDHHC 60
Query: 61 YKTCPEKTYSEAVECKACDSNCSSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGE 120
YKTCPEKTYSEAVECKACDSNC SCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGE
Sbjct: 61 YKTCPEKTYSEAVECKACDSNCGSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGE 120
Query: 121 CESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSC 180
CESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSC
Sbjct: 121 CESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSC 180
Query: 181 KTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKKC 240
KTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKKC
Sbjct: 181 KTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKKC 240
Query: 241 QMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEGGHVLHHGV 300
QMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEGGHVLHHGV
Sbjct: 241 QMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEGGHVLHHGV 300
Query: 301 CQENCPERHVAVEGVCKHCPEMCQDCIHEKTCKECMPEFFLHDDMCHQSCPRGFYADSHH 360
CQENCPERHVAV+GVCKHCPEMCQDCIHEKTCKEC PEFFLHDDMCHQSCPRGFYADS H
Sbjct: 301 CQENCPERHVAVKGVCKHCPEMCQDCIHEKTCKECTPEFFLHDDMCHQSCPRGFYADSRH 360
Query: 361 CVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKQTKECRDCHKSCLT 420
CVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEK+TKECRDCHKSCLT
Sbjct: 361 CVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKETKECRDCHKSCLT 420
Query: 421 CSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQ 480
CSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQ
Sbjct: 421 CSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQ 480
Query: 481 TCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGK 540
TCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGK
Sbjct: 481 TCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGK 540
Query: 541 ECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDH 600
ECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDH
Sbjct: 541 ECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDH 600
Query: 601 YYVEQSTQTCERCHPTCDQCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFN 660
YYVEQSTQTCERCHPTCDQCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFN
Sbjct: 601 YYVEQSTQTCERCHPTCDQCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFN 660
Query: 661 CEKCHESCMECKGPGAKNCTLCPANLVLHMDESHCLHCCNTSDPPSAQECCDCQDTTDEC 720
CEKCHESCMECKGPGAKNCTLCPANLVLHMD+SHCLHCCNTSDPPSAQECCDCQDTTDEC
Sbjct: 661 CEKCHESCMECKGPGAKNCTLCPANLVLHMDDSHCLHCCNTSDPPSAQECCDCQDTTDEC 720
Query: 721 ILRTSKVRPATEHFKTALFITSSMMLVLLLGAAVVVWKKSRGRVQPAAKAGYEKLADPNK 780
ILRTSKVRPATEHFKTALFITSSMMLVLLLGAAVVVWKKSRGRVQPAAKAGYEKLADPNK
Sbjct: 721 ILRTSKVRPATEHFKTALFITSSMMLVLLLGAAVVVWKKSRGRVQPAAKAGYEKLADPNK 780
Query: 781 SYSSYKSSYRESTSFEEDQVIEYRDRDYDEDDDDDIVYMGQDGTVYRKFKYGLLDDDDID 840
SYSSYKSSYRESTSFEEDQVIEYRDRDYDEDDDDDIVYMGQDGTVYRKFKYGLLDDDDID
Sbjct: 781 SYSSYKSSYRESTSFEEDQVIEYRDRDYDEDDDDDIVYMGQDGTVYRKFKYGLLDDDDID 840
Query: 841 ELEYDDESYSYYQ 853
ELEYDDESYSYYQ
Sbjct: 841 ELEYDDESYSYYQ 853
>gi|239743863 PREDICTED: hypothetical protein XP_002342982 [Homo
sapiens]
Length = 853
Score = 1909 bits (4946), Expect = 0.0
Identities = 846/853 (99%), Positives = 849/853 (99%)
Query: 1 MKWILGKNNCADFEGVPQMMLTSIGKILGIGQSNVVTREGDPPVQKQIHLKCGNRFDHHC 60
MKWILGKNNCADFEGVPQMMLTSIGKILGIGQSNVVTREGDPPVQKQIHLKCGNRFDHHC
Sbjct: 1 MKWILGKNNCADFEGVPQMMLTSIGKILGIGQSNVVTREGDPPVQKQIHLKCGNRFDHHC 60
Query: 61 YKTCPEKTYSEAVECKACDSNCSSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGE 120
YKTCPEKTYSE VECKACDSNC SCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGE
Sbjct: 61 YKTCPEKTYSEEVECKACDSNCGSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGE 120
Query: 121 CESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSC 180
CESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSC
Sbjct: 121 CESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSC 180
Query: 181 KTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKKC 240
KTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKKC
Sbjct: 181 KTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKKC 240
Query: 241 QMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEGGHVLHHGV 300
QMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEGGHVLHHGV
Sbjct: 241 QMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEGGHVLHHGV 300
Query: 301 CQENCPERHVAVEGVCKHCPEMCQDCIHEKTCKECMPEFFLHDDMCHQSCPRGFYADSHH 360
CQENCPERHVAV+GVCKHCPEMCQDCIHEKTCKEC PEFFLHDDMCHQSCPRGFYADS H
Sbjct: 301 CQENCPERHVAVKGVCKHCPEMCQDCIHEKTCKECTPEFFLHDDMCHQSCPRGFYADSRH 360
Query: 361 CVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKQTKECRDCHKSCLT 420
CVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEK+TKECRDCHKSCLT
Sbjct: 361 CVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKETKECRDCHKSCLT 420
Query: 421 CSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQ 480
CSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQ
Sbjct: 421 CSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQ 480
Query: 481 TCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGK 540
TCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGK
Sbjct: 481 TCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGK 540
Query: 541 ECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDH 600
ECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDH
Sbjct: 541 ECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDH 600
Query: 601 YYVEQSTQTCERCHPTCDQCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFN 660
YYVEQSTQTCERCHPTCDQCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFN
Sbjct: 601 YYVEQSTQTCERCHPTCDQCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFN 660
Query: 661 CEKCHESCMECKGPGAKNCTLCPANLVLHMDESHCLHCCNTSDPPSAQECCDCQDTTDEC 720
CEKCHESCMECKGPGAKNCTLCPANLVLHMD+SHCLHCCNTSDPPSAQECCDCQDTTDEC
Sbjct: 661 CEKCHESCMECKGPGAKNCTLCPANLVLHMDDSHCLHCCNTSDPPSAQECCDCQDTTDEC 720
Query: 721 ILRTSKVRPATEHFKTALFITSSMMLVLLLGAAVVVWKKSRGRVQPAAKAGYEKLADPNK 780
ILRTSKVRPATEHFKTALFITSSMMLVLLLGAAVVVWKKSRGRVQPAAKAGYEKLADPNK
Sbjct: 721 ILRTSKVRPATEHFKTALFITSSMMLVLLLGAAVVVWKKSRGRVQPAAKAGYEKLADPNK 780
Query: 781 SYSSYKSSYRESTSFEEDQVIEYRDRDYDEDDDDDIVYMGQDGTVYRKFKYGLLDDDDID 840
SYSSYKSSYRESTSFEEDQVIEYRDRDYDEDDDDDIVYMGQDGTVYRKFKYGLLDDDDID
Sbjct: 781 SYSSYKSSYRESTSFEEDQVIEYRDRDYDEDDDDDIVYMGQDGTVYRKFKYGLLDDDDID 840
Query: 841 ELEYDDESYSYYQ 853
ELEYDDESYSYYQ
Sbjct: 841 ELEYDDESYSYYQ 853
>gi|108773804 Fraser syndrome 1 [Homo sapiens]
Length = 4011
Score = 315 bits (806), Expect = 1e-85
Identities = 206/668 (30%), Positives = 283/668 (42%), Gaps = 63/668 (9%)
Query: 60 CYKTCPEKTYSEAVECKACDSNCSSCDQN-GCYWCEEGFFLLGGSCVRKCGPGFYGDQEM 118
C +C Y C AC CS+C C C+ + G CV CG GFY D+
Sbjct: 450 CVHSCGLGFYQAGSLCLACQPQCSTCTSGLECSSCQPPLLMRHGQCVPTCGDGFYQDRH- 508
Query: 119 GECESCHRACETCTGPGHDECSSCQEGLQLLR-GMCVHATKTQEEGKFWNDILRKLQPCH 177
C CH +C C GP C +C++ L +LR G C + GK + + C
Sbjct: 509 -SCAVCHESCAGCWGPTEKHCLACRDPLHVLRDGGCESSC-----GKGFYNRQGTCSACD 562
Query: 178 SSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSG--AD 235
SC +C S+ C +C + L C+S CP G + +G C+ C +CA CSG
Sbjct: 563 QSCDSCGPSSPRCLTCTEKTVLHDGKCMSECPGGYYADA-TGRCKVCHNSCASCSGPTPS 621
Query: 236 LCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNA-TNCHSC---- 290
C C P L +G C +C EG Y++ G+C+ C S C C G A ++C C
Sbjct: 622 HCTAC----SPPKALRQGHCLPRCGEGFYSDHGVCKACHSSCLACMGPAPSHCTGCKKPE 677
Query: 291 EGGHV-------LHHGVCQENCPERHVAVE--GVCKHCPEMCQDCIHEK--TCKECMPEF 339
EG V + G C C H +E G+C+ C + C C + C +C P
Sbjct: 678 EGLQVEQLSDVGIPSGECLAQC-RAHFYLESTGICEACHQSCFRCAGKSPHNCTDCGPSH 736
Query: 340 FLHDDMCHQSCPRGFYADSHHCVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECP 399
L D C CP G++ C CH C +C GP DC C L +G C C
Sbjct: 737 VLLDGQCLSQCPDGYFHQEGSCTECHPTCRQCHGPLESDCISCYPHI-SLTNGNCRTSCR 795
Query: 400 AGTYYEKQTKECRDCHKSCLTC-----SSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYW 454
+ C DCH C C ++ C CQ + C+ + PS Y+
Sbjct: 796 EEQFL-NLVGYCADCHHLCQHCAADLHNTGSICLRCQNAHYLLLGDHCVPD---CPSGYY 851
Query: 455 DEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNT-TCVKDCPEGYYADEDSNRCAHC 513
E CK CH C C G C +C N +L +T TC C G+Y D D++ C C
Sbjct: 852 AERG-ACKKCHSSCRTCQGRGPFSCSSCDTNLVLSHTGTCSTTCFPGHYLD-DNHVCQPC 909
Query: 514 HSSCRTCEGRHSRQCHSCR-PGWFQLGKECLLQ-CREGYYADNSTGRCERCNRSCKGCQG 571
++ C +C+ + S C SCR P L EC + C YY D ST C+ C+ SC C G
Sbjct: 910 NTHCGSCDSQAS--CTSCRDPNKVLLFGECQYESCAPQYYLDFSTNTCKECDWSCSACSG 967
Query: 572 PRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALNCLSC 631
P TDCL C + L G C C +Y Q + C +C C QC+G C C
Sbjct: 968 PLKTDCLQCMDGYVL--QDGACVEQCLSSFY--QDSGLC-KCDSYCLQCQGPH--ECTRC 1020
Query: 632 VWSYHLMGGICTSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGAKNCTLCPANLVLHMD 691
+ L+ C +C G+ + K C C + C++C C LC L
Sbjct: 1021 KGPFLLLEAQCVQEC--GKGYFADHAKHKCTACPQGCLQCS--HRDRCHLCDHGFFL--K 1074
Query: 692 ESHCLHCC 699
C++ C
Sbjct: 1075 SGLCVYNC 1082
Score = 311 bits (797), Expect = 2e-84
Identities = 216/656 (32%), Positives = 291/656 (44%), Gaps = 75/656 (11%)
Query: 78 CDSNCSSCDQNG--CYWCEEGFFLL-GGSCVRKCGPGFYGDQEMGECESCHRACETCTGP 134
C +C +C Q+ C C++ LL G CV CG GFY Q C +C C TCT
Sbjct: 421 CHPDCLTCSQSPDHCDLCQDPTKLLQNGWCVHSCGLGFY--QAGSLCLACQPQCSTCTSG 478
Query: 135 GHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSCKTCNGSATL-CTSC 193
ECSSCQ L + G CV T +G F+ D CH SC C G C +C
Sbjct: 479 L--ECSSCQPPLLMRHGQCV---PTCGDG-FYQD-RHSCAVCHESCAGCWGPTEKHCLAC 531
Query: 194 PKGAYLLAQA-CVSSCPQGTWPSVRSGSCENCTEACAICS-GADLCKKCQMQPGHPLFLH 251
++L C SSC +G + R G+C C ++C C + C C + LH
Sbjct: 532 RDPLHVLRDGGCESSCGKGFYN--RQGTCSACDQSCDSCGPSSPRCLTCTEKT----VLH 585
Query: 252 EGRCYSKCPEGSYAE-DGICERCSSPCRTCEG-NATNCHSCEGGHVLHHGVCQENCPERH 309
+G+C S+CP G YA+ G C+ C + C +C G ++C +C L G C C E
Sbjct: 586 DGKCMSECPGGYYADATGRCKVCHNSCASCSGPTPSHCTACSPPKALRQGHCLPRCGEGF 645
Query: 310 VAVEGVCKHCPEMCQDCI-----HEKTCK--------ECMPEFFLHDDMCHQSCPRGFYA 356
+ GVCK C C C+ H CK E + + + C C FY
Sbjct: 646 YSDHGVCKACHSSCLACMGPAPSHCTGCKKPEEGLQVEQLSDVGIPSGECLAQCRAHFYL 705
Query: 357 DSHH-CVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKQTKECRDCH 415
+S C CH+ C C+G +C C S VL DG CL +CP G ++++ + C +CH
Sbjct: 706 ESTGICEACHQSCFRCAGKSPHNCTDC-GPSHVLLDGQCLSQCPDGYFHQEGS--CTECH 762
Query: 416 KSCLTCSS--SGTCTTCQKGLIM---NPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFH 470
+C C C +C + + N R SC + + Y C CH C H
Sbjct: 763 PTCRQCHGPLESDCISCYPHISLTNGNCRTSCREEQFLNLVGY-------CADCHHLCQH 815
Query: 471 CMGPAEDQCQTC----PMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSR 526
C + C + LLL CV DCP GYYA+ + C CHSSCRTC+GR
Sbjct: 816 CAADLHNTGSICLRCQNAHYLLLGDHCVPDCPSGYYAERGA--CKKCHSSCRTCQGRGPF 873
Query: 527 QCHSCRPGW-FQLGKECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSC-DRFF 584
C SC C C G+Y D++ C+ CN C C C SC D
Sbjct: 874 SCSSCDTNLVLSHTGTCSTTCFPGHYLDDNHV-CQPCNTHCGSCDSQ--ASCTSCRDPNK 930
Query: 585 FLLRSKGEC-HRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALNCLSCVWSYHLMGGICT 643
LL GEC + SC YY++ ST TC+ C +C C G +CL C+ Y L G C
Sbjct: 931 VLLF--GECQYESCAPQYYLDFSTNTCKECDWSCSACSGPLKTDCLQCMDGYVLQDGACV 988
Query: 644 SDCLVGEYRVGEGEKFNCEKCHESCMECKGPGAKNCTLCPANLVLHMDESHCLHCC 699
CL Y+ + C KC C++C+GP CT C +L E+ C+ C
Sbjct: 989 EQCLSSFYQ----DSGLC-KCDSYCLQCQGP--HECTRCKGPFLLL--EAQCVQEC 1035
Score = 307 bits (787), Expect = 2e-83
Identities = 182/616 (29%), Positives = 272/616 (44%), Gaps = 51/616 (8%)
Query: 60 CYKTCPEKTYSEAVECKACDSNCSSC---DQNGCYWCEEGFFLL-GGSCVRKCGPGFYGD 115
C TC + Y + C C +C+ C + C C + +L G C CG GFY
Sbjct: 495 CVPTCGDGFYQDRHSCAVCHESCAGCWGPTEKHCLACRDPLHVLRDGGCESSCGKGFYNR 554
Query: 116 QEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQP 175
Q G C +C ++C++C GP C +C E L G C+ ++ G ++ D + +
Sbjct: 555 Q--GTCSACDQSCDSC-GPSSPRCLTCTEKTVLHDGKCM----SECPGGYYADATGRCKV 607
Query: 176 CHSSCKTCNG-SATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSG- 233
CH+SC +C+G + + CT+C L C+ C +G + G C+ C +C C G
Sbjct: 608 CHNSCASCSGPTPSHCTACSPPKALRQGHCLPRCGEGFYSD--HGVCKACHSSCLACMGP 665
Query: 234 ----ADLCKK----CQMQPGHPLFLHEGRCYSKCPEGSYAED-GICERCSSPCRTCEGNA 284
CKK Q++ + + G C ++C Y E GICE C C C G +
Sbjct: 666 APSHCTGCKKPEEGLQVEQLSDVGIPSGECLAQCRAHFYLESTGICEACHQSCFRCAGKS 725
Query: 285 T-NCHSCEGGHVLHHGVCQENCPERHVAVEGVCKHCPEMCQDCIH--EKTCKECMPEFFL 341
NC C HVL G C CP+ + EG C C C+ C E C C P L
Sbjct: 726 PHNCTDCGPSHVLLDGQCLSQCPDGYFHQEGSCTECHPTCRQCHGPLESDCISCYPHISL 785
Query: 342 HDDMCHQSCPRGFYADS-HHCVPCHKDCLECSGPKADDCELCLE---SSWVLYDGLCLEE 397
+ C SC + + +C CH C C+ + +CL + ++L C+ +
Sbjct: 786 TNGNCRTSCREEQFLNLVGYCADCHHLCQHCAADLHNTGSICLRCQNAHYLLLGDHCVPD 845
Query: 398 CPAGTYYEKQTKECRDCHKSCLTCSSSG--TCTTCQKGLIMNPRGSCMANEKCSPSEYWD 455
CP+G Y E+ C+ CH SC TC G +C++C L+++ G+C C P Y D
Sbjct: 846 CPSGYYAERGA--CKKCHSSCRTCQGRGPFSCSSCDTNLVLSHTGTCSTT--CFPGHYLD 901
Query: 456 EDAPGCKPCHVKCFHCMGPAEDQCQTC--PMNSLLLNTTCVKDCPEGYYADEDSNRCAHC 513
++ C+PC+ C C ++ C +C P LL + C YY D +N C C
Sbjct: 902 DNHV-CQPCNTHCGSC--DSQASCTSCRDPNKVLLFGECQYESCAPQYYLDFSTNTCKEC 958
Query: 514 HSSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNSTGRCERCNRSCKGCQGPR 573
SC C G C C G+ C+ QC +Y D +G C +C+ C CQGP
Sbjct: 959 DWSCSACSGPLKTDCLQCMDGYVLQDGACVEQCLSSFYQD--SGLC-KCDSYCLQCQGPH 1015
Query: 574 PTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALNCLSCVW 633
+C C F LL + +C + C Y+ + + C C C QC + C C
Sbjct: 1016 --ECTRCKGPFLLL--EAQCVQECGKGYFADHAKHKCTACPQGCLQCSHRD--RCHLCDH 1069
Query: 634 SYHLMGGICTSDCLVG 649
+ L G+C +C+ G
Sbjct: 1070 GFFLKSGLCVYNCVPG 1085
Score = 298 bits (762), Expect = 2e-80
Identities = 176/576 (30%), Positives = 260/576 (45%), Gaps = 42/576 (7%)
Query: 57 DHHCYKTCPEKTYSEAVECKACDSNCSSCDQNG--CYWCEEGFFLLGGSCVRKCGPGFYG 114
D C +C + Y+ C ACD +C SC + C C E L G C+ +C G+Y
Sbjct: 540 DGGCESSCGKGFYNRQGTCSACDQSCDSCGPSSPRCLTCTEKTVLHDGKCMSECPGGYYA 599
Query: 115 DQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQ 174
D G C+ CH +C +C+GP C++C L +G C+ EG F++D +
Sbjct: 600 D-ATGRCKVCHNSCASCSGPTPSHCTACSPPKALRQGHCLPRC---GEG-FYSD-HGVCK 653
Query: 175 PCHSSCKTCNGSA-TLCTSCPK-----------GAYLLAQACVSSCPQGTWPSVRSGSCE 222
CHSSC C G A + CT C K + + C++ C + + +G CE
Sbjct: 654 ACHSSCLACMGPAPSHCTGCKKPEEGLQVEQLSDVGIPSGECLAQC-RAHFYLESTGICE 712
Query: 223 NCTEACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEG 282
C ++C C+G P H L +G+C S+CP+G + ++G C C CR C G
Sbjct: 713 ACHQSCFRCAGKSPHNCTDCGPSHVLL--DGQCLSQCPDGYFHQEGSCTECHPTCRQCHG 770
Query: 283 N-ATNCHSCEGGHVLHHGVCQENC-PERHVAVEGVCKHCPEMCQDCIHE-----KTCKEC 335
++C SC L +G C+ +C E+ + + G C C +CQ C + C C
Sbjct: 771 PLESDCISCYPHISLTNGNCRTSCREEQFLNLVGYCADCHHLCQHCAADLHNTGSICLRC 830
Query: 336 M-PEFFLHDDMCHQSCPRGFYADSHHCVPCHKDCLECSGPKADDCELCLESSWVLYDGLC 394
+ L D C CP G+YA+ C CH C C G C C + + + G C
Sbjct: 831 QNAHYLLLGDHCVPDCPSGYYAERGACKKCHSSCRTCQGRGPFSCSSCDTNLVLSHTGTC 890
Query: 395 LEECPAGTYYEKQTKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYW 454
C G Y + C+ C+ C +C S +CT+C+ + G C E C+P Y
Sbjct: 891 STTCFPGHYLD-DNHVCQPCNTHCGSCDSQASCTSCRDPNKVLLFGECQ-YESCAPQYYL 948
Query: 455 DEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCH 514
D CK C C C GP + C C +L + CV+ C +Y +DS C C
Sbjct: 949 DFSTNTCKECDWSCSACSGPLKTDCLQCMDGYVLQDGACVEQCLSSFY--QDSGLC-KCD 1005
Query: 515 SSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNSTGRCERCNRSCKGCQGPRP 574
S C C+G H +C C+ + L +C+ +C +GY+AD++ +C C + C C
Sbjct: 1006 SYCLQCQGPH--ECTRCKGPFLLLEAQCVQECGKGYFADHAKHKCTACPQGCLQCS--HR 1061
Query: 575 TDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTC 610
C CD FFL G C +C + V S +TC
Sbjct: 1062 DRCHLCDHGFFL--KSGLCVYNCVPGFSVHTSNETC 1095
Score = 276 bits (705), Expect = 8e-74
Identities = 192/704 (27%), Positives = 264/704 (37%), Gaps = 131/704 (18%)
Query: 107 KCGPGFYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFW 166
+CG G + G+C CE C P G C + + + + W
Sbjct: 260 RCGKGQSRARRHGQC------CEECVSPA---------------GSCSYDGVVRYQDEMW 298
Query: 167 NDILRKLQPCHSSCKTCNGSATLCTSCPKGAYLL------AQACVSSCPQGTWPSVRSGS 220
+ C TC C + L+ C+S +
Sbjct: 299 KGSACEFCMCDHGQVTCQTGECAKVECARDEELIHLDGKCCPECISRNGYCVYEETGEFM 358
Query: 221 CENCTEACAICSGADL----CKKCQMQPGHPLFLHEGRCYSKCPEGSYA---EDGICERC 273
N +E I G CK C+ + G + +E C CP G+ A + C C
Sbjct: 359 SSNASEVKRIPEGEKWEDGPCKVCECR-GAQVTCYEPSC-PPCPVGTLALEVKGQCCPDC 416
Query: 274 SS-----PCRTCEGNATNCHSCEGG-HVLHHGVCQENCPERHVAVEGVCKHCPEMCQDCI 327
+S C TC + +C C+ +L +G C +C +C C C C
Sbjct: 417 TSVHCHPDCLTCSQSPDHCDLCQDPTKLLQNGWCVHSCGLGFYQAGSLCLACQPQCSTCT 476
Query: 328 HEKTCKECMPEFFLHDDMCHQSCPRGFYADSHHCVPCHKDCLECSGPKADDCELCLESSW 387
C C P + C +C GFY D H C CH+ C C GP C C +
Sbjct: 477 SGLECSSCQPPLLMRHGQCVPTCGDGFYQDRHSCAVCHESCAGCWGPTEKHCLACRDPLH 536
Query: 388 VLYDGLCLEECPAGTYYEKQTKECRDCHKSCLTCS-SSGTCTTCQKGLIMNPRGSCMANE 446
VL DG C C G Y + T C C +SC +C SS C TC + +++ G CM+
Sbjct: 537 VLRDGGCESSCGKGFYNRQGT--CSACDQSCDSCGPSSPRCLTCTEKTVLHD-GKCMSE- 592
Query: 447 KCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADED 506
P Y+ + CK CH C C GP C C L C+ C EG+Y+D
Sbjct: 593 --CPGGYYADATGRCKVCHNSCASCSGPTPSHCTACSPPKALRQGHCLPRCGEGFYSDH- 649
Query: 507 SNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQL-----------GKECLLQCREGYYADNS 555
C CHSSC C G C C+ L ECL QCR +Y + S
Sbjct: 650 -GVCKACHSSCLACMGPAPSHCTGCKKPEEGLQVEQLSDVGIPSGECLAQCRAHFYLE-S 707
Query: 556 TGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHP 615
TG CE C++SC C G P +C C LL G+C CPD Y+ ++ +C CHP
Sbjct: 708 TGICEACHQSCFRCAGKSPHNCTDCGPSHVLL--DGQCLSQCPDGYFHQEG--SCTECHP 763
Query: 616 TCDQCKGKGALNCLSCVWSYHLMGGICTSDC----------------------------- 646
TC QC G +C+SC L G C + C
Sbjct: 764 TCRQCHGPLESDCISCYPHISLTNGNCRTSCREEQFLNLVGYCADCHHLCQHCAADLHNT 823
Query: 647 -------------LVGEYRVGE------GEKFNCEKCHESCMECKGPGAKNCTLCPANLV 687
L+G++ V + E+ C+KCH SC C+G G +C+ C NLV
Sbjct: 824 GSICLRCQNAHYLLLGDHCVPDCPSGYYAERGACKKCHSSCRTCQGRGPFSCSSCDTNLV 883
Query: 688 L--------------HMDESHCLHCCNT--SDPPSAQECCDCQD 715
L ++D++H CNT S C C+D
Sbjct: 884 LSHTGTCSTTCFPGHYLDDNHVCQPCNTHCGSCDSQASCTSCRD 927
Score = 223 bits (567), Expect = 8e-58
Identities = 150/499 (30%), Positives = 215/499 (43%), Gaps = 57/499 (11%)
Query: 59 HCYKTCPEKTYSEAVECKACDSNCSSC------DQNGCYWCEEGF--------FLLGGSC 104
HC C E YS+ CKAC S+C +C GC EEG + G C
Sbjct: 636 HCLPRCGEGFYSDHGVCKACHSSCLACMGPAPSHCTGCKKPEEGLQVEQLSDVGIPSGEC 695
Query: 105 VRKCGPGFYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGK 164
+ +C FY + G CE+CH++C C G C+ C LL G C+ +G
Sbjct: 696 LAQCRAHFY-LESTGICEACHQSCFRCAGKSPHNCTDCGPSHVLLDGQCLSQC---PDGY 751
Query: 165 FWNDILRKLQPCHSSCKTCNGS-ATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCEN 223
F + CH +C+ C+G + C SC L C +SC + + ++ G C +
Sbjct: 752 FHQE--GSCTECHPTCRQCHGPLESDCISCYPHISLTNGNCRTSCREEQFLNL-VGYCAD 808
Query: 224 CTEACAICSG-----ADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCR 278
C C C+ +C +C Q H L L + C CP G YAE G C++C S CR
Sbjct: 809 CHHLCQHCAADLHNTGSICLRC--QNAHYLLLGD-HCVPDCPSGYYAERGACKKCHSSCR 865
Query: 279 TCEGNAT-NCHSCEGGHVLHH-GVCQENC-PERHVAVEGVCKHCPEMCQDCIHEKTCKEC 335
TC+G +C SC+ VL H G C C P ++ VC+ C C C + +C C
Sbjct: 866 TCQGRGPFSCSSCDTNLVLSHTGTCSTTCFPGHYLDDNHVCQPCNTHCGSCDSQASCTSC 925
Query: 336 MP--EFFLHDDMCHQSCPRGFYAD--SHHCVPCHKDCLECSGPKADDCELCLESSWVLYD 391
+ L + ++SC +Y D ++ C C C CSGP DC C++ +VL D
Sbjct: 926 RDPNKVLLFGECQYESCAPQYYLDFSTNTCKECDWSCSACSGPLKTDCLQCMD-GYVLQD 984
Query: 392 GLCLEECPAGTYYEKQTKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPS 451
G C+E+C + Y + C+ C CL C CT C KG + C+ ++C
Sbjct: 985 GACVEQCLSSFYQDSGL--CK-CDSYCLQCQGPHECTRC-KGPFLLLEAQCV--QECGKG 1038
Query: 452 EYWDEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCA 511
+ D C C C C D+C C L + CV +C G+
Sbjct: 1039 YFADHAKHKCTACPQGCLQC--SHRDRCHLCDHGFFLKSGLCVYNCVPGF---------- 1086
Query: 512 HCHSSCRTCEGR-HSRQCH 529
H+S TC G+ H+ H
Sbjct: 1087 SVHTSNETCSGKIHTPSLH 1105
Score = 207 bits (528), Expect = 3e-53
Identities = 190/757 (25%), Positives = 267/757 (35%), Gaps = 202/757 (26%)
Query: 142 CQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSCKTCNGSATLCTSCPKGAYLLA 201
C E + G C H K E G W PC S +CN CT P
Sbjct: 84 CPECVLRTPGSCHHEKKIHEHGTEWAS-----SPC--SVCSCNHGEVRCTPQPCPPLSCG 136
Query: 202 QACVSSCPQGTWPSVRSGSCENCT-EACAICSGAD----LCKKCQMQPG---------HP 247
++ P+G+ V G + C+ E G D C KC + G P
Sbjct: 137 HQELAFIPEGSCCPVCVGLGKPCSYEGHVFQDGEDWRLSRCAKCLCRNGVAQCFTAQCQP 196
Query: 248 LFLHE--------GRCYSKCPEGSYAEDGIC-----ERCSSPCRT--CEGNATNCHS--- 289
LF ++ G+C +C S + G + + C T C+ CH
Sbjct: 197 LFCNQDETVVRVPGKCCPQCSARSCSAAGQVYEHGEQWSENACTTCICDRGEVRCHKQAC 256
Query: 290 ----CEGG--HVLHHGVCQENC--PERHVAVEGVCKHCPEM-----CQDCIHE------- 329
C G HG C E C P + +GV ++ EM C+ C+ +
Sbjct: 257 LPLRCGKGQSRARRHGQCCEECVSPAGSCSYDGVVRYQDEMWKGSACEFCMCDHGQVTCQ 316
Query: 330 --------------------KTCKECMP-----------EFF---------------LHD 343
K C EC+ EF D
Sbjct: 317 TGECAKVECARDEELIHLDGKCCPECISRNGYCVYEETGEFMSSNASEVKRIPEGEKWED 376
Query: 344 DMCHQSCPRGFYADSHH--CVPCHKD--CLECSGPKADDC-------------------E 380
C RG + C PC LE G DC +
Sbjct: 377 GPCKVCECRGAQVTCYEPSCPPCPVGTLALEVKGQCCPDCTSVHCHPDCLTCSQSPDHCD 436
Query: 381 LCLESSWVLYDGLCLEECPAGTYYEKQTKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRG 440
LC + + +L +G C+ C G Y + C C C TC+S C++CQ L+M G
Sbjct: 437 LCQDPTKLLQNGWCVHSCGLGFY--QAGSLCLACQPQCSTCTSGLECSSCQPPLLMR-HG 493
Query: 441 SCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAE------------------------ 476
C+ C Y +D C CH C C GP E
Sbjct: 494 QCVPT--CGDGFY--QDRHSCAVCHESCAGCWGPTEKHCLACRDPLHVLRDGGCESSCGK 549
Query: 477 -----------------------DQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHC 513
+C TC ++L + C+ +CP GYYAD + RC C
Sbjct: 550 GFYNRQGTCSACDQSCDSCGPSSPRCLTCTEKTVLHDGKCMSECPGGYYADA-TGRCKVC 608
Query: 514 HSSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNSTGRCERCNRSCKGCQGPR 573
H+SC +C G C +C P CL +C EG+Y+D+ G C+ C+ SC C GP
Sbjct: 609 HNSCASCSGPTPSHCTACSPPKALRQGHCLPRCGEGFYSDH--GVCKACHSSCLACMGPA 666
Query: 574 PTDCLSC---------DRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKG 624
P+ C C ++ + GEC C H+Y+E ST CE CH +C +C GK
Sbjct: 667 PSHCTGCKKPEEGLQVEQLSDVGIPSGECLAQCRAHFYLE-STGICEACHQSCFRCAGKS 725
Query: 625 ALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGAKNCTLCPA 684
NC C S+ L+ G C S C G + ++ +C +CH +C +C GP +C C
Sbjct: 726 PHNCTDCGPSHVLLDGQCLSQCPDGYFH----QEGSCTECHPTCRQCHGPLESDCISCYP 781
Query: 685 NLVLHMDESHCLHCCNTSDPPS-AQECCDCQDTTDEC 720
++ L +C C + C DC C
Sbjct: 782 HISL--TNGNCRTSCREEQFLNLVGYCADCHHLCQHC 816
Score = 118 bits (295), Expect = 3e-26
Identities = 88/294 (29%), Positives = 120/294 (40%), Gaps = 32/294 (10%)
Query: 48 IHLKCGNR----FDHHCYKTCPEKTYSEAVECKACDSNCSSCDQNG---CYWCEEGFFLL 100
I L+C N HC CP Y+E CK C S+C +C G C C+ L
Sbjct: 826 ICLRCQNAHYLLLGDHCVPDCPSGYYAERGACKKCHSSCRTCQGRGPFSCSSCDTNLVLS 885
Query: 101 -GGSCVRKCGPGFYGDQEMGECESCHRACETCTGPGHDECSSCQE-GLQLLRGMCVHATK 158
G+C C PG Y D + C+ C+ C +C C+SC++ LL G C + +
Sbjct: 886 HTGTCSTTCFPGHYLD-DNHVCQPCNTHCGSCDSQA--SCTSCRDPNKVLLFGECQYESC 942
Query: 159 TQEEGKFWNDILRKLQPCHSSCKTCNGS-ATLCTSCPKGAYLLAQACVSSCPQGTWPSVR 217
+ + + + C SC C+G T C C G L ACV C +
Sbjct: 943 APQ--YYLDFSTNTCKECDWSCSACSGPLKTDCLQCMDGYVLQDGACVEQCLSSFYQD-- 998
Query: 218 SGSCENCTEACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDG--ICERCSS 275
SG C+ C C C G C +C+ P L E +C +C +G +A+ C C
Sbjct: 999 SGLCK-CDSYCLQCQGPHECTRCK----GPFLLLEAQCVQECGKGYFADHAKHKCTACPQ 1053
Query: 276 PCRTCEGNATNCHSCEGGHVLHHGVCQENCPERHVAVEGVCKHCP-EMCQDCIH 328
C C + CH C+ G L G+C NC V G H E C IH
Sbjct: 1054 GCLQC-SHRDRCHLCDHGFFLKSGLCVYNC------VPGFSVHTSNETCSGKIH 1100
>gi|20336246 proprotein convertase subtilisin/kexin type 5
preproprotein [Homo sapiens]
Length = 913
Score = 156 bits (395), Expect = 7e-38
Identities = 90/249 (36%), Positives = 117/249 (46%), Gaps = 20/249 (8%)
Query: 452 EYWDEDAPGCKPCHVKCFH--CMGPAEDQCQTC-PMNSLLLNTT--CVKDCPEGYYADED 506
+Y ED G PC +C C GP D C C L N T CV CP G+Y D
Sbjct: 626 DYGTEDYAG--PCDPECSEVGCDGPGPDHCNDCLHYYYKLKNNTRICVSSCPPGHY-HAD 682
Query: 507 SNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGKE---CLLQCREGYYADNSTGRCERCN 563
RC C +C +C G H QC SC+ G+F L +E C+ C +G Y D C +C+
Sbjct: 683 KKRCRKCAPNCESCFGSHGDQCMSCKYGYF-LNEETNSCVTHCPDGSYQDTKKNLCRKCS 741
Query: 564 RSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGK 623
+CK C +C C L S+ C SC D Y + Q C+ CH C C G
Sbjct: 742 ENCKTCTEFH--NCTECRDGLSLQGSR--CSVSCEDGRYF--NGQDCQPCHRFCATCAGA 795
Query: 624 GALNCLSCVWSYHLMGGICTSDCLVGEY--RVGEGEKFNCEKCHESCMECKGPGAKNCTL 681
GA C++C Y + G C C + Y E +C+KC SC+ C GPG KNCT
Sbjct: 796 GADGCINCTEGYFMEDGRCVQSCSISYYFDHSSENGYKSCKKCDISCLTCNGPGFKNCTS 855
Query: 682 CPANLVLHM 690
CP+ +L +
Sbjct: 856 CPSGYLLDL 864
Score = 141 bits (355), Expect = 3e-33
Identities = 86/300 (28%), Positives = 114/300 (38%), Gaps = 63/300 (21%)
Query: 351 PRGFYADSHHCVPCHKDCLE--CSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKQT 408
P Y + PC +C E C GP D C CL YY K
Sbjct: 623 PTDDYGTEDYAGPCDPECSEVGCDGPGPDHCNDCLH------------------YYYKLK 664
Query: 409 KECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKC 468
R C SC P ++ D C+ C C
Sbjct: 665 NNTRICVSSC-------------------------------PPGHYHADKKRCRKCAPNC 693
Query: 469 FHCMGPAEDQCQTCPMNSLLLNTT--CVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSR 526
C G DQC +C L T CV CP+G Y D N C C +C+TC H+
Sbjct: 694 ESCFGSHGDQCMSCKYGYFLNEETNSCVTHCPDGSYQDTKKNLCRKCSENCKTCTEFHN- 752
Query: 527 QCHSCRPGWFQLGKECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFL 586
C CR G G C + C +G Y + C+ C+R C C G C++C +F+
Sbjct: 753 -CTECRDGLSLQGSRCSVSCEDGRYFNGQD--CQPCHRFCATCAGAGADGCINCTEGYFM 809
Query: 587 LRSKGECHRSCPDHYYVEQSTQ----TCERCHPTCDQCKGKGALNCLSCVWSYHLMGGIC 642
G C +SC YY + S++ +C++C +C C G G NC SC Y L G+C
Sbjct: 810 --EDGRCVQSCSISYYFDHSSENGYKSCKKCDISCLTCNGPGFKNCTSCPSGYLLDLGMC 867
Score = 135 bits (340), Expect = 2e-31
Identities = 79/254 (31%), Positives = 116/254 (45%), Gaps = 18/254 (7%)
Query: 218 SGSCE-NCTEACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSY-AEDGICERCSS 275
+G C+ C+E G D C C + + L + C S CP G Y A+ C +C+
Sbjct: 633 AGPCDPECSEVGCDGPGPDHCNDC-LHYYYKLKNNTRICVSSCPPGHYHADKKRCRKCAP 691
Query: 276 PCRTCEGN-ATNCHSCEGGHVLHHGV--CQENCPERHV--AVEGVCKHCPEMCQDCIHEK 330
C +C G+ C SC+ G+ L+ C +CP+ + +C+ C E C+ C
Sbjct: 692 NCESCFGSHGDQCMSCKYGYFLNEETNSCVTHCPDGSYQDTKKNLCRKCSENCKTCTEFH 751
Query: 331 TCKECMPEFFLHDDMCHQSCPRGFYADSHHCVPCHKDCLECSGPKADDCELCLESSWVLY 390
C EC L C SC G Y + C PCH+ C C+G AD C C E + +
Sbjct: 752 NCTECRDGLSLQGSRCSVSCEDGRYFNGQDCQPCHRFCATCAGAGADGCINCTE-GYFME 810
Query: 391 DGLCLEECPAGTYYEKQT----KECRDCHKSCLTCSSSG--TCTTCQKGLIMNPRGSCMA 444
DG C++ C Y++ + K C+ C SCLTC+ G CT+C G +++ G C
Sbjct: 811 DGRCVQSCSISYYFDHSSENGYKSCKKCDISCLTCNGPGFKNCTSCPSGYLLD-LGMCQM 869
Query: 445 NEKC--SPSEYWDE 456
C + E W E
Sbjct: 870 GAICKDATEESWAE 883
Score = 113 bits (283), Expect = 7e-25
Identities = 90/299 (30%), Positives = 120/299 (40%), Gaps = 40/299 (13%)
Query: 65 PEKTYSEAVECKACDSNCSS--CDQNG---CYWCEEGFFLLGGS---CVRKCGPGFYGDQ 116
P Y CD CS CD G C C ++ L + CV C PG Y
Sbjct: 623 PTDDYGTEDYAGPCDPECSEVGCDGPGPDHCNDCLHYYYKLKNNTRICVSSCPPGHY-HA 681
Query: 117 EMGECESCHRACETCTGPGHDECSSCQEG--LQLLRGMCV-HATKTQEEGKFWNDILRKL 173
+ C C CE+C G D+C SC+ G L CV H +G + +
Sbjct: 682 DKKRCRKCAPNCESCFGSHGDQCMSCKYGYFLNEETNSCVTHC----PDGSYQDTKKNLC 737
Query: 174 QPCHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAIC-- 231
+ C +CKTC CT C G L C SC G + C+ C CA C
Sbjct: 738 RKCSENCKTCTEFHN-CTECRDGLSLQGSRCSVSCEDGRY--FNGQDCQPCHRFCATCAG 794
Query: 232 SGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSY----AEDGI--CERCSSPCRTCEG-NA 284
+GAD C C F+ +GRC C Y +E+G C++C C TC G
Sbjct: 795 AGADGCINCT----EGYFMEDGRCVQSCSISYYFDHSSENGYKSCKKCDISCLTCNGPGF 850
Query: 285 TNCHSCEGGHVLHHGVCQ-----ENCPERHVAVEGVCKHCPE--MCQ-DCIHEKTCKEC 335
NC SC G++L G+CQ ++ E A G C + +CQ + + CK C
Sbjct: 851 KNCTSCPSGYLLDLGMCQMGAICKDATEESWAEGGFCMLVKKNNLCQRKVLQQLCCKTC 909
Score = 96.7 bits (239), Expect = 8e-20
Identities = 63/208 (30%), Positives = 91/208 (43%), Gaps = 37/208 (17%)
Query: 54 NRFDHHCYKTCPEKTYSEAVE--CKACDSNCSSCDQ-NGCYWCEEGFFLLGGSCVRKCGP 110
N + C CP+ +Y + + C+ C NC +C + + C C +G L G C C
Sbjct: 714 NEETNSCVTHCPDGSYQDTKKNLCRKCSENCKTCTEFHNCTECRDGLSLQGSRCSVSCED 773
Query: 111 GFYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATK-------TQEEG 163
G Y + + +C+ CHR C TC G G D C +C EG + G CV + + E G
Sbjct: 774 GRYFNGQ--DCQPCHRFCATCAGAGADGCINCTEGYFMEDGRCVQSCSISYYFDHSSENG 831
Query: 164 KFWNDILRKLQPCHSSCKTCNGSA-TLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCE 222
+ + C SC TCNG CTSCP G YLL + C G C+
Sbjct: 832 ------YKSCKKCDISCLTCNGPGFKNCTSCPSG-YLLD---LGMCQMG-------AICK 874
Query: 223 NCTEA-------CAICSGADLCKKCQMQ 243
+ TE C + +LC++ +Q
Sbjct: 875 DATEESWAEGGFCMLVKKNNLCQRKVLQ 902
>gi|4505577 paired basic amino acid cleaving system 4 isoform a
preproprotein [Homo sapiens]
Length = 969
Score = 141 bits (355), Expect = 3e-33
Identities = 85/275 (30%), Positives = 119/275 (43%), Gaps = 25/275 (9%)
Query: 364 CHKDCLE--CSGPKADDCELCLESSW--VLYDGLCLEECPAGTYYEKQTKECRDCHKSCL 419
CH +C + C GP AD C C+ S V C+ CP G + + + CR CHK C
Sbjct: 695 CHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCE 754
Query: 420 TCSSSGT--CTTCQKGLIMNPR-GSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAE 476
TCSS C +C++G + +C+ C Y DE C CH C C+ E
Sbjct: 755 TCSSRAATQCLSCRRGFYHHQEMNTCVT--LCPAGFYADESQKNCLKCHPSCKKCVDEPE 812
Query: 477 DQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWF 536
+C C L +C+ DC G Y D + RC CH +C TC G +C C +
Sbjct: 813 -KCTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFH 871
Query: 537 QLGKECLLQCREGYYADNSTGR----CERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGE 592
+C+ C EG+Y + G C RC+ +C C G +C C F L +
Sbjct: 872 FHDWKCVPACGEGFYPEEMPGLPHKVCRRCDENCLSCAG-SSRNCSRCKTGFTQLGTSCI 930
Query: 593 CHRSC--PDHYYVE--QSTQTCER------CHPTC 617
+ +C D + E +S + CER C TC
Sbjct: 931 TNHTCSNADETFCEMVKSNRLCERKLFIQFCCRTC 965
Score = 131 bits (330), Expect = 2e-30
Identities = 66/226 (29%), Positives = 100/226 (44%), Gaps = 23/226 (10%)
Query: 513 CHSSC--RTCEGRHSRQCHSC---RPGWFQLGKECLLQCREGYYADNSTGRCERCNRSCK 567
CH C + C+G ++ QC +C G + ++C+ C GY+ D + RC RC++ C+
Sbjct: 695 CHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCE 754
Query: 568 GCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALN 627
C T CLSC R F+ + C CP +Y ++S + C +CHP+C +C +
Sbjct: 755 TCSSRAATQCLSCRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKCHPSCKKCVDEPE-K 813
Query: 628 CLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGAKNCTLCPANLV 687
C C + L G C DC G Y + E C +CH +C C GPG + C C N
Sbjct: 814 CTVCKEGFSLARGSCIPDCEPGTY--FDSELIRCGECHHTCGTCVGPGREECIHCAKN-- 869
Query: 688 LHMDESHCLHCCNTSDPPSA-------------QECCDCQDTTDEC 720
H + C+ C P + C C ++ C
Sbjct: 870 FHFHDWKCVPACGEGFYPEEMPGLPHKVCRRCDENCLSCAGSSRNC 915
Score = 117 bits (292), Expect = 6e-26
Identities = 66/228 (28%), Positives = 92/228 (40%), Gaps = 20/228 (8%)
Query: 79 DSNCSSCDQNGCYWCEEGFFLLGG-----SCVRKCGPGFYGDQEMGECESCHRACETCTG 133
D C + + C C F LG CV C G++GD C CH+ CETC+
Sbjct: 701 DKGCDGPNADQCLNCVH--FSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCETCSS 758
Query: 134 PGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSCKTCNGSATLCTSC 193
+C SC+ G + M T G + ++ + CH SCK C CT C
Sbjct: 759 RAATQCLSCRRGFYHHQEMNTCVTLC-PAGFYADESQKNCLKCHPSCKKCVDEPEKCTVC 817
Query: 194 PKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAIC--SGADLCKKCQMQPGHPLFLH 251
+G L +C+ C GT+ C C C C G + C C H
Sbjct: 818 KEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKN----FHFH 873
Query: 252 EGRCYSKCPEGSYAED------GICERCSSPCRTCEGNATNCHSCEGG 293
+ +C C EG Y E+ +C RC C +C G++ NC C+ G
Sbjct: 874 DWKCVPACGEGFYPEEMPGLPHKVCRRCDENCLSCAGSSRNCSRCKTG 921
Score = 110 bits (275), Expect = 6e-24
Identities = 78/245 (31%), Positives = 103/245 (42%), Gaps = 23/245 (9%)
Query: 254 RCYSKCPEGSYAEDGI--CERCSSPCRTCEGNA-TNCHSCEGGHVLHH--GVCQENCPER 308
+C S CP G + + C RC C TC A T C SC G H C CP
Sbjct: 728 KCVSVCPLGYFGDTAARRCRRCHKGCETCSSRAATQCLSCRRGFYHHQEMNTCVTLCPAG 787
Query: 309 HVAVEGV--CKHCPEMCQDCIHE-KTCKECMPEFFLHDDMCHQSCPRGFYADSH--HCVP 363
A E C C C+ C+ E + C C F L C C G Y DS C
Sbjct: 788 FYADESQKNCLKCHPSCKKCVDEPEKCTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGE 847
Query: 364 CHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKQT----KECRDCHKSCL 419
CH C C GP ++C C + ++ +D C+ C G Y E+ K CR C ++CL
Sbjct: 848 CHHTCGTCVGPGREECIHCAK-NFHFHDWKCVPACGEGFYPEEMPGLPHKVCRRCDENCL 906
Query: 420 TCS-SSGTCTTCQKGLIMNPRGSCMANEKCS-PSEYWDEDAPGCKPCHVKCFHCMGPAED 477
+C+ SS C+ C+ G SC+ N CS E + E + C K F +
Sbjct: 907 SCAGSSRNCSRCKTGFTQLGT-SCITNHTCSNADETFCEMVKSNRLCERKLF-----IQF 960
Query: 478 QCQTC 482
C+TC
Sbjct: 961 CCRTC 965
Score = 103 bits (258), Expect = 5e-22
Identities = 61/204 (29%), Positives = 88/204 (43%), Gaps = 28/204 (13%)
Query: 50 LKCGNRFDHH-----CYKTCPEKTYSEAVE--CKACDSNCSSC--DQNGCYWCEEGFFLL 100
L C F HH C CP Y++ + C C +C C + C C+EGF L
Sbjct: 765 LSCRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKCHPSCKKCVDEPEKCTVCKEGFSLA 824
Query: 101 GGSCVRKCGPGFYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQ 160
GSC+ C PG Y D E+ C CH C TC GPG +EC C + CV A
Sbjct: 825 RGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFHFHDWKCVPAC--- 881
Query: 161 EEGKFWNDI----LRKLQPCHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSV 216
EG + ++ + + C +C +C GS+ C+ C G L +C++
Sbjct: 882 GEGFYPEEMPGLPHKVCRRCDENCLSCAGSSRNCSRCKTGFTQLGTSCIT---------- 931
Query: 217 RSGSCENCTEA-CAICSGADLCKK 239
+ +C N E C + LC++
Sbjct: 932 -NHTCSNADETFCEMVKSNRLCER 954
Score = 101 bits (251), Expect = 3e-21
Identities = 66/227 (29%), Positives = 97/227 (42%), Gaps = 23/227 (10%)
Query: 176 CHSSC--KTCNG-SATLCTSCPK---GAYLLAQACVSSCPQGTWPSVRSGSCENCTEACA 229
CH C K C+G +A C +C G+ ++ CVS CP G + + C C + C
Sbjct: 695 CHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCE 754
Query: 230 ICSG--ADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGI--CERCSSPCRTCEGNAT 285
CS A C C+ H ++ C + CP G YA++ C +C C+ C
Sbjct: 755 TCSSRAATQCLSCRRGFYHHQEMNT--CVTLCPAGFYADESQKNCLKCHPSCKKCVDEPE 812
Query: 286 NCHSCEGGHVLHHGVCQENC-PERHVAVEGV-CKHCPEMCQDCIH--EKTCKECMPEFFL 341
C C+ G L G C +C P + E + C C C C+ + C C F
Sbjct: 813 KCTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFHF 872
Query: 342 HDDMCHQSCPRGFYADSHHCVP------CHKDCLECSGPKADDCELC 382
HD C +C GFY + +P C ++CL C+G + +C C
Sbjct: 873 HDWKCVPACGEGFYPEEMPGLPHKVCRRCDENCLSCAG-SSRNCSRC 918
>gi|20336180 paired basic amino acid cleaving system 4 isoform b
preproprotein [Homo sapiens]
Length = 956
Score = 141 bits (355), Expect = 3e-33
Identities = 85/275 (30%), Positives = 119/275 (43%), Gaps = 25/275 (9%)
Query: 364 CHKDCLE--CSGPKADDCELCLESSW--VLYDGLCLEECPAGTYYEKQTKECRDCHKSCL 419
CH +C + C GP AD C C+ S V C+ CP G + + + CR CHK C
Sbjct: 682 CHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCE 741
Query: 420 TCSSSGT--CTTCQKGLIMNPR-GSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAE 476
TCSS C +C++G + +C+ C Y DE C CH C C+ E
Sbjct: 742 TCSSRAATQCLSCRRGFYHHQEMNTCVT--LCPAGFYADESQKNCLKCHPSCKKCVDEPE 799
Query: 477 DQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWF 536
+C C L +C+ DC G Y D + RC CH +C TC G +C C +
Sbjct: 800 -KCTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFH 858
Query: 537 QLGKECLLQCREGYYADNSTGR----CERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGE 592
+C+ C EG+Y + G C RC+ +C C G +C C F L +
Sbjct: 859 FHDWKCVPACGEGFYPEEMPGLPHKVCRRCDENCLSCAG-SSRNCSRCKTGFTQLGTSCI 917
Query: 593 CHRSC--PDHYYVE--QSTQTCER------CHPTC 617
+ +C D + E +S + CER C TC
Sbjct: 918 TNHTCSNADETFCEMVKSNRLCERKLFIQFCCRTC 952
Score = 132 bits (331), Expect = 2e-30
Identities = 66/235 (28%), Positives = 104/235 (44%), Gaps = 23/235 (9%)
Query: 504 DEDSNRCAHCHSSC--RTCEGRHSRQCHSC---RPGWFQLGKECLLQCREGYYADNSTGR 558
+++ + CH C + C+G ++ QC +C G + ++C+ C GY+ D + R
Sbjct: 673 EDEEDYTGVCHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARR 732
Query: 559 CERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCD 618
C RC++ C+ C T CLSC R F+ + C CP +Y ++S + C +CHP+C
Sbjct: 733 CRRCHKGCETCSSRAATQCLSCRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKCHPSCK 792
Query: 619 QCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGAKN 678
+C + C C + L G C DC G Y + E C +CH +C C GPG +
Sbjct: 793 KCVDEPE-KCTVCKEGFSLARGSCIPDCEPGTY--FDSELIRCGECHHTCGTCVGPGREE 849
Query: 679 CTLCPANLVLHMDESHCLHCCNTSDPPSA-------------QECCDCQDTTDEC 720
C C N H + C+ C P + C C ++ C
Sbjct: 850 CIHCAKN--FHFHDWKCVPACGEGFYPEEMPGLPHKVCRRCDENCLSCAGSSRNC 902
Score = 119 bits (297), Expect = 2e-26
Identities = 68/241 (28%), Positives = 97/241 (40%), Gaps = 20/241 (8%)
Query: 66 EKTYSEAVECKACDSNCSSCDQNGCYWCEEGFFLLGG-----SCVRKCGPGFYGDQEMGE 120
E+ Y+ + D C + + C C F LG CV C G++GD
Sbjct: 675 EEDYTGVCHPECGDKGCDGPNADQCLNCVH--FSLGSVKTSRKCVSVCPLGYFGDTAARR 732
Query: 121 CESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSC 180
C CH+ CETC+ +C SC+ G + M T G + ++ + CH SC
Sbjct: 733 CRRCHKGCETCSSRAATQCLSCRRGFYHHQEMNTCVTLC-PAGFYADESQKNCLKCHPSC 791
Query: 181 KTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAIC--SGADLCK 238
K C CT C +G L +C+ C GT+ C C C C G + C
Sbjct: 792 KKCVDEPEKCTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECI 851
Query: 239 KCQMQPGHPLFLHEGRCYSKCPEGSYAED------GICERCSSPCRTCEGNATNCHSCEG 292
C H+ +C C EG Y E+ +C RC C +C G++ NC C+
Sbjct: 852 HCAKN----FHFHDWKCVPACGEGFYPEEMPGLPHKVCRRCDENCLSCAGSSRNCSRCKT 907
Query: 293 G 293
G
Sbjct: 908 G 908
Score = 110 bits (275), Expect = 6e-24
Identities = 78/245 (31%), Positives = 103/245 (42%), Gaps = 23/245 (9%)
Query: 254 RCYSKCPEGSYAEDGI--CERCSSPCRTCEGNA-TNCHSCEGGHVLHH--GVCQENCPER 308
+C S CP G + + C RC C TC A T C SC G H C CP
Sbjct: 715 KCVSVCPLGYFGDTAARRCRRCHKGCETCSSRAATQCLSCRRGFYHHQEMNTCVTLCPAG 774
Query: 309 HVAVEGV--CKHCPEMCQDCIHE-KTCKECMPEFFLHDDMCHQSCPRGFYADSH--HCVP 363
A E C C C+ C+ E + C C F L C C G Y DS C
Sbjct: 775 FYADESQKNCLKCHPSCKKCVDEPEKCTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGE 834
Query: 364 CHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKQT----KECRDCHKSCL 419
CH C C GP ++C C + ++ +D C+ C G Y E+ K CR C ++CL
Sbjct: 835 CHHTCGTCVGPGREECIHCAK-NFHFHDWKCVPACGEGFYPEEMPGLPHKVCRRCDENCL 893
Query: 420 TCS-SSGTCTTCQKGLIMNPRGSCMANEKCS-PSEYWDEDAPGCKPCHVKCFHCMGPAED 477
+C+ SS C+ C+ G SC+ N CS E + E + C K F +
Sbjct: 894 SCAGSSRNCSRCKTGFTQLGT-SCITNHTCSNADETFCEMVKSNRLCERKLF-----IQF 947
Query: 478 QCQTC 482
C+TC
Sbjct: 948 CCRTC 952
Score = 103 bits (258), Expect = 5e-22
Identities = 61/204 (29%), Positives = 88/204 (43%), Gaps = 28/204 (13%)
Query: 50 LKCGNRFDHH-----CYKTCPEKTYSEAVE--CKACDSNCSSC--DQNGCYWCEEGFFLL 100
L C F HH C CP Y++ + C C +C C + C C+EGF L
Sbjct: 752 LSCRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKCHPSCKKCVDEPEKCTVCKEGFSLA 811
Query: 101 GGSCVRKCGPGFYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQ 160
GSC+ C PG Y D E+ C CH C TC GPG +EC C + CV A
Sbjct: 812 RGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFHFHDWKCVPAC--- 868
Query: 161 EEGKFWNDI----LRKLQPCHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSV 216
EG + ++ + + C +C +C GS+ C+ C G L +C++
Sbjct: 869 GEGFYPEEMPGLPHKVCRRCDENCLSCAGSSRNCSRCKTGFTQLGTSCIT---------- 918
Query: 217 RSGSCENCTEA-CAICSGADLCKK 239
+ +C N E C + LC++
Sbjct: 919 -NHTCSNADETFCEMVKSNRLCER 941
Score = 101 bits (251), Expect = 3e-21
Identities = 66/227 (29%), Positives = 97/227 (42%), Gaps = 23/227 (10%)
Query: 176 CHSSC--KTCNG-SATLCTSCPK---GAYLLAQACVSSCPQGTWPSVRSGSCENCTEACA 229
CH C K C+G +A C +C G+ ++ CVS CP G + + C C + C
Sbjct: 682 CHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCE 741
Query: 230 ICSG--ADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGI--CERCSSPCRTCEGNAT 285
CS A C C+ H ++ C + CP G YA++ C +C C+ C
Sbjct: 742 TCSSRAATQCLSCRRGFYHHQEMNT--CVTLCPAGFYADESQKNCLKCHPSCKKCVDEPE 799
Query: 286 NCHSCEGGHVLHHGVCQENC-PERHVAVEGV-CKHCPEMCQDCIH--EKTCKECMPEFFL 341
C C+ G L G C +C P + E + C C C C+ + C C F
Sbjct: 800 KCTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFHF 859
Query: 342 HDDMCHQSCPRGFYADSHHCVP------CHKDCLECSGPKADDCELC 382
HD C +C GFY + +P C ++CL C+G + +C C
Sbjct: 860 HDWKCVPACGEGFYPEEMPGLPHKVCRRCDENCLSCAG-SSRNCSRC 905
>gi|20336184 paired basic amino acid cleaving system 4 isoform h
preproprotein [Homo sapiens]
Length = 962
Score = 137 bits (346), Expect = 3e-32
Identities = 74/204 (36%), Positives = 92/204 (45%), Gaps = 12/204 (5%)
Query: 455 DEDAPGCKPCHVKCFH--CMGPAEDQCQTC---PMNSLLLNTTCVKDCPEGYYADEDSNR 509
+ED G CH +C C GP DQC C + S+ + CV CP GY+ D + R
Sbjct: 675 EEDYTGV--CHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARR 732
Query: 510 CAHCHSSCRTCEGRHSRQCHSCRPGWF--QLGKECLLQCREGYYADNSTGRCERCNRSCK 567
C CH C TC R + QC SCR G++ Q C+ C G+YAD S C +C+ SCK
Sbjct: 733 CRRCHKGCETCSSRAATQCLSCRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKCHPSCK 792
Query: 568 GCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALN 627
C P C C F L R G C C Y + C CH TC C G G
Sbjct: 793 KCVD-EPEKCTVCKEGFSLAR--GSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREE 849
Query: 628 CLSCVWSYHLMGGICTSDCLVGEY 651
C+ C ++H C C G Y
Sbjct: 850 CIHCAKNFHFHDWKCVPACGEGFY 873
Score = 131 bits (330), Expect = 2e-30
Identities = 62/201 (30%), Positives = 97/201 (48%), Gaps = 10/201 (4%)
Query: 504 DEDSNRCAHCHSSC--RTCEGRHSRQCHSC---RPGWFQLGKECLLQCREGYYADNSTGR 558
+++ + CH C + C+G ++ QC +C G + ++C+ C GY+ D + R
Sbjct: 673 EDEEDYTGVCHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARR 732
Query: 559 CERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCD 618
C RC++ C+ C T CLSC R F+ + C CP +Y ++S + C +CHP+C
Sbjct: 733 CRRCHKGCETCSSRAATQCLSCRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKCHPSCK 792
Query: 619 QCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGAKN 678
+C + C C + L G C DC G Y + E C +CH +C C GPG +
Sbjct: 793 KCVDEPE-KCTVCKEGFSLARGSCIPDCEPGTY--FDSELIRCGECHHTCGTCVGPGREE 849
Query: 679 CTLCPANLVLHMDESHCLHCC 699
C C N H + C+ C
Sbjct: 850 CIHCAKN--FHFHDWKCVPAC 868
Score = 124 bits (312), Expect = 3e-28
Identities = 65/201 (32%), Positives = 90/201 (44%), Gaps = 10/201 (4%)
Query: 364 CHKDCLE--CSGPKADDCELCLESSW--VLYDGLCLEECPAGTYYEKQTKECRDCHKSCL 419
CH +C + C GP AD C C+ S V C+ CP G + + + CR CHK C
Sbjct: 682 CHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCE 741
Query: 420 TCSSSGT--CTTCQKGLIMNPR-GSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAE 476
TCSS C +C++G + +C+ C Y DE C CH C C+ E
Sbjct: 742 TCSSRAATQCLSCRRGFYHHQEMNTCVT--LCPAGFYADESQKNCLKCHPSCKKCVDEPE 799
Query: 477 DQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWF 536
+C C L +C+ DC G Y D + RC CH +C TC G +C C +
Sbjct: 800 -KCTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFH 858
Query: 537 QLGKECLLQCREGYYADNSTG 557
+C+ C EG+Y + G
Sbjct: 859 FHDWKCVPACGEGFYPEEMPG 879
Score = 98.6 bits (244), Expect = 2e-20
Identities = 61/224 (27%), Positives = 86/224 (38%), Gaps = 20/224 (8%)
Query: 66 EKTYSEAVECKACDSNCSSCDQNGCYWCEEGFFLLGG-----SCVRKCGPGFYGDQEMGE 120
E+ Y+ + D C + + C C F LG CV C G++GD
Sbjct: 675 EEDYTGVCHPECGDKGCDGPNADQCLNCVH--FSLGSVKTSRKCVSVCPLGYFGDTAARR 732
Query: 121 CESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSC 180
C CH+ CETC+ +C SC+ G + M T G + ++ + CH SC
Sbjct: 733 CRRCHKGCETCSSRAATQCLSCRRGFYHHQEMNTCVTLC-PAGFYADESQKNCLKCHPSC 791
Query: 181 KTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAIC--SGADLCK 238
K C CT C +G L +C+ C GT+ C C C C G + C
Sbjct: 792 KKCVDEPEKCTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECI 851
Query: 239 KCQMQPGHPLFLHEGRCYSKCPEGSYAED------GICERCSSP 276
C H+ +C C EG Y E+ +C R P
Sbjct: 852 HCAKN----FHFHDWKCVPACGEGFYPEEMPGLPHKVCRRYGPP 891
Score = 94.7 bits (234), Expect = 3e-19
Identities = 66/227 (29%), Positives = 95/227 (41%), Gaps = 18/227 (7%)
Query: 176 CHSSC--KTCNG-SATLCTSCPK---GAYLLAQACVSSCPQGTWPSVRSGSCENCTEACA 229
CH C K C+G +A C +C G+ ++ CVS CP G + + C C + C
Sbjct: 682 CHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCE 741
Query: 230 ICSG--ADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGI--CERCSSPCRTCEGNAT 285
CS A C C+ H ++ C + CP G YA++ C +C C+ C
Sbjct: 742 TCSSRAATQCLSCRRGFYHHQEMNT--CVTLCPAGFYADESQKNCLKCHPSCKKCVDEPE 799
Query: 286 NCHSCEGGHVLHHGVCQENC-PERHVAVEGV-CKHCPEMCQDCIH--EKTCKECMPEFFL 341
C C+ G L G C +C P + E + C C C C+ + C C F
Sbjct: 800 KCTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFHF 859
Query: 342 HDDMCHQSCPRGFYADSHHCVPCHKDCLECSGPKADDCELCLESSWV 388
HD C +C GFY + +P HK C GP + + + S V
Sbjct: 860 HDWKCVPACGEGFYPEEMPGLP-HKVCRR-YGPPGGERQAAVSSKGV 904
Score = 91.3 bits (225), Expect = 3e-18
Identities = 55/175 (31%), Positives = 75/175 (42%), Gaps = 26/175 (14%)
Query: 562 CNRSC--KGCQGPRPTDCLSCDRFFF-LLRSKGECHRSCPDHYYVEQSTQTCERCHPTCD 618
C+ C KGC GP CL+C F +++ +C CP Y+ + + + C RCH C+
Sbjct: 682 CHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCE 741
Query: 619 QCKGKGALNCLSCV--WSYHLMGGICTSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGA 676
C + A CLSC + +H C + C G Y E +K NC KCH SC +C
Sbjct: 742 TCSSRAATQCLSCRRGFYHHQEMNTCVTLCPAGFY-ADESQK-NCLKCHPSCKKCVDEPE 799
Query: 677 KNCTLCPANLVL-------------HMDES-----HCLHCCNTSDPPSAQECCDC 713
K CT+C L + D C H C T P +EC C
Sbjct: 800 K-CTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHC 853
Score = 87.8 bits (216), Expect = 4e-17
Identities = 43/116 (37%), Positives = 53/116 (45%), Gaps = 9/116 (7%)
Query: 50 LKCGNRFDHH-----CYKTCPEKTYSEAVE--CKACDSNCSSC--DQNGCYWCEEGFFLL 100
L C F HH C CP Y++ + C C +C C + C C+EGF L
Sbjct: 752 LSCRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKCHPSCKKCVDEPEKCTVCKEGFSLA 811
Query: 101 GGSCVRKCGPGFYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHA 156
GSC+ C PG Y D E+ C CH C TC GPG +EC C + CV A
Sbjct: 812 RGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFHFHDWKCVPA 867
>gi|20336182 paired basic amino acid cleaving system 4 isoform g
preproprotein [Homo sapiens]
Length = 975
Score = 137 bits (344), Expect = 6e-32
Identities = 71/195 (36%), Positives = 88/195 (45%), Gaps = 10/195 (5%)
Query: 464 CHVKCFH--CMGPAEDQCQTC---PMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCR 518
CH +C C GP DQC C + S+ + CV CP GY+ D + RC CH C
Sbjct: 695 CHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCE 754
Query: 519 TCEGRHSRQCHSCRPGWF--QLGKECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTD 576
TC R + QC SCR G++ Q C+ C G+YAD S C +C+ SCK C P
Sbjct: 755 TCSSRAATQCLSCRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKCHPSCKKCVD-EPEK 813
Query: 577 CLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALNCLSCVWSYH 636
C C F L R G C C Y + C CH TC C G G C+ C ++H
Sbjct: 814 CTVCKEGFSLAR--GSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFH 871
Query: 637 LMGGICTSDCLVGEY 651
C C G Y
Sbjct: 872 FHDWKCVPACGEGFY 886
Score = 131 bits (329), Expect = 3e-30
Identities = 62/192 (32%), Positives = 93/192 (48%), Gaps = 10/192 (5%)
Query: 513 CHSSC--RTCEGRHSRQCHSC---RPGWFQLGKECLLQCREGYYADNSTGRCERCNRSCK 567
CH C + C+G ++ QC +C G + ++C+ C GY+ D + RC RC++ C+
Sbjct: 695 CHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCE 754
Query: 568 GCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALN 627
C T CLSC R F+ + C CP +Y ++S + C +CHP+C +C +
Sbjct: 755 TCSSRAATQCLSCRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKCHPSCKKCVDEPE-K 813
Query: 628 CLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGAKNCTLCPANLV 687
C C + L G C DC G Y + E C +CH +C C GPG + C C N
Sbjct: 814 CTVCKEGFSLARGSCIPDCEPGTY--FDSELIRCGECHHTCGTCVGPGREECIHCAKN-- 869
Query: 688 LHMDESHCLHCC 699
H + C+ C
Sbjct: 870 FHFHDWKCVPAC 881
Score = 124 bits (312), Expect = 3e-28
Identities = 65/201 (32%), Positives = 90/201 (44%), Gaps = 10/201 (4%)
Query: 364 CHKDCLE--CSGPKADDCELCLESSW--VLYDGLCLEECPAGTYYEKQTKECRDCHKSCL 419
CH +C + C GP AD C C+ S V C+ CP G + + + CR CHK C
Sbjct: 695 CHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCE 754
Query: 420 TCSSSGT--CTTCQKGLIMNPR-GSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAE 476
TCSS C +C++G + +C+ C Y DE C CH C C+ E
Sbjct: 755 TCSSRAATQCLSCRRGFYHHQEMNTCVT--LCPAGFYADESQKNCLKCHPSCKKCVDEPE 812
Query: 477 DQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWF 536
+C C L +C+ DC G Y D + RC CH +C TC G +C C +
Sbjct: 813 -KCTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFH 871
Query: 537 QLGKECLLQCREGYYADNSTG 557
+C+ C EG+Y + G
Sbjct: 872 FHDWKCVPACGEGFYPEEMPG 892
Score = 96.7 bits (239), Expect = 8e-20
Identities = 59/211 (27%), Positives = 81/211 (38%), Gaps = 20/211 (9%)
Query: 79 DSNCSSCDQNGCYWCEEGFFLLGG-----SCVRKCGPGFYGDQEMGECESCHRACETCTG 133
D C + + C C F LG CV C G++GD C CH+ CETC+
Sbjct: 701 DKGCDGPNADQCLNCVH--FSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCETCSS 758
Query: 134 PGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSCKTCNGSATLCTSC 193
+C SC+ G + M T G + ++ + CH SCK C CT C
Sbjct: 759 RAATQCLSCRRGFYHHQEMNTCVTLC-PAGFYADESQKNCLKCHPSCKKCVDEPEKCTVC 817
Query: 194 PKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAIC--SGADLCKKCQMQPGHPLFLH 251
+G L +C+ C GT+ C C C C G + C C H
Sbjct: 818 KEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKN----FHFH 873
Query: 252 EGRCYSKCPEGSYAED------GICERCSSP 276
+ +C C EG Y E+ +C R P
Sbjct: 874 DWKCVPACGEGFYPEEMPGLPHKVCRRYGPP 904
Score = 94.7 bits (234), Expect = 3e-19
Identities = 66/227 (29%), Positives = 95/227 (41%), Gaps = 18/227 (7%)
Query: 176 CHSSC--KTCNG-SATLCTSCPK---GAYLLAQACVSSCPQGTWPSVRSGSCENCTEACA 229
CH C K C+G +A C +C G+ ++ CVS CP G + + C C + C
Sbjct: 695 CHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCE 754
Query: 230 ICSG--ADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGI--CERCSSPCRTCEGNAT 285
CS A C C+ H ++ C + CP G YA++ C +C C+ C
Sbjct: 755 TCSSRAATQCLSCRRGFYHHQEMNT--CVTLCPAGFYADESQKNCLKCHPSCKKCVDEPE 812
Query: 286 NCHSCEGGHVLHHGVCQENC-PERHVAVEGV-CKHCPEMCQDCIH--EKTCKECMPEFFL 341
C C+ G L G C +C P + E + C C C C+ + C C F
Sbjct: 813 KCTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFHF 872
Query: 342 HDDMCHQSCPRGFYADSHHCVPCHKDCLECSGPKADDCELCLESSWV 388
HD C +C GFY + +P HK C GP + + + S V
Sbjct: 873 HDWKCVPACGEGFYPEEMPGLP-HKVCRR-YGPPGGERQAAVSSKGV 917
Score = 91.7 bits (226), Expect = 3e-18
Identities = 59/194 (30%), Positives = 82/194 (42%), Gaps = 31/194 (15%)
Query: 548 EGYYADNSTG-----RCERCNRSC--KGCQGPRPTDCLSCDRFFF-LLRSKGECHRSCPD 599
E Y A ++ G + C+ C KGC GP CL+C F +++ +C CP
Sbjct: 676 EDYTAQSTPGSANILQTSVCHPECGDKGCDGPNADQCLNCVHFSLGSVKTSRKCVSVCPL 735
Query: 600 HYYVEQSTQTCERCHPTCDQCKGKGALNCLSCV--WSYHLMGGICTSDCLVGEYRVGEGE 657
Y+ + + + C RCH C+ C + A CLSC + +H C + C G Y E +
Sbjct: 736 GYFGDTAARRCRRCHKGCETCSSRAATQCLSCRRGFYHHQEMNTCVTLCPAGFY-ADESQ 794
Query: 658 KFNCEKCHESCMECKGPGAKNCTLCPANLVL-------------HMDES-----HCLHCC 699
K NC KCH SC +C K CT+C L + D C H C
Sbjct: 795 K-NCLKCHPSCKKCVDEPEK-CTVCKEGFSLARGSCIPDCEPGTYFDSELIRCGECHHTC 852
Query: 700 NTSDPPSAQECCDC 713
T P +EC C
Sbjct: 853 GTCVGPGREECIHC 866
Score = 87.8 bits (216), Expect = 4e-17
Identities = 43/116 (37%), Positives = 53/116 (45%), Gaps = 9/116 (7%)
Query: 50 LKCGNRFDHH-----CYKTCPEKTYSEAVE--CKACDSNCSSC--DQNGCYWCEEGFFLL 100
L C F HH C CP Y++ + C C +C C + C C+EGF L
Sbjct: 765 LSCRRGFYHHQEMNTCVTLCPAGFYADESQKNCLKCHPSCKKCVDEPEKCTVCKEGFSLA 824
Query: 101 GGSCVRKCGPGFYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHA 156
GSC+ C PG Y D E+ C CH C TC GPG +EC C + CV A
Sbjct: 825 RGSCIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFHFHDWKCVPA 880
Score = 45.1 bits (105), Expect = 3e-04
Identities = 26/81 (32%), Positives = 32/81 (39%), Gaps = 8/81 (9%)
Query: 60 CYKTCPEKTY--SEAVECKACDSNCSSCDQNG---CYWCEEGFFLLGGSCVRKCGPGFYG 114
C C TY SE + C C C +C G C C + F CV CG GFY
Sbjct: 828 CIPDCEPGTYFDSELIRCGECHHTCGTCVGPGREECIHCAKNFHFHDWKCVPACGEGFYP 887
Query: 115 DQEMGECESCHRACETCTGPG 135
++ G H+ C PG
Sbjct: 888 EEMPG---LPHKVCRRYGPPG 905
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 130 bits (328), Expect = 4e-30
Identities = 170/675 (25%), Positives = 233/675 (34%), Gaps = 154/675 (22%)
Query: 78 CDSNCS-----SCD-QNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGECESCHRA-CE- 129
CD CS SCD ++G C G L +C++ C PG+YG C+ CH A C+
Sbjct: 144 CDKPCSCGNNSSCDPKSGVCSCPSG--LQPPNCLQPCTPGYYGPACQFRCQ-CHGAPCDP 200
Query: 130 ---TC------TGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSC 180
C TGP D SC +G C Q G F Q SC
Sbjct: 201 QTGACFCPAERTGPSCD--VSCSQGTSGF--FCPSTHSCQNGGVF--------QTPQGSC 248
Query: 181 KTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKK- 239
SCP G + C CP+G NC++ C C LC +
Sbjct: 249 -----------SCPPG--WMGTICSLPCPEGF-------HGPNCSQECR-CHNGGLCDRF 287
Query: 240 ---CQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEGGHVL 296
C+ PG+ RC +CP G + +D C+ C C +A C G +
Sbjct: 288 TGQCRCAPGYT----GDRCREECPVGRFGQD-----CAETC-DCAPDA-RCFPANGACLC 336
Query: 297 HHGVCQENCPERHV--AVEGVCKHCPEMCQDCIHEKTCK------ECMPEFF-LHDDMCH 347
HG + C +R G+ P C D H +C C+P + LH C+
Sbjct: 337 EHGFTGDRCTDRLCPDGFYGLSCQAPCTC-DREHSLSCHPMNGECSCLPGWAGLH---CN 392
Query: 348 QSCPRGFYADSHHCVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKQ 407
+SCP+ H C + CL G + + C CP TY
Sbjct: 393 ESCPQ-----DTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNC 447
Query: 408 TKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVK 467
+ C C + G C C++G RG+C + C P + C+ H
Sbjct: 448 SARC-SCENAIACSPIDGEC-VCKEGW---QRGNC--SVPCPPGTWGFSCNASCQCAH-- 498
Query: 468 CFHCMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQ 527
Q C C CP+G + + ++RC HS C+ H R
Sbjct: 499 ----EAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSD--GCDPVHGR- 551
Query: 528 CHSCRPGWFQLGKECLLQCREGYYADNSTGRC-----------------------ERCNR 564
C C+ GW +G C L C EG + N + C C R
Sbjct: 552 C-QCQAGW--MGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQR 608
Query: 565 SCK-GCQGPRPTDCLSCDRFFFLLRSKG-----------ECHRSCPDHYYVEQSTQTCER 612
SC+ G G R C C F S G +C + CP ++ E QTC+
Sbjct: 609 SCQPGRYGKRCVPC-KCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQ- 666
Query: 613 CH--PTCDQCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFNC---EKCHES 667
CH TC G SC+ G C C +G + + C EKCH
Sbjct: 667 CHHGGTCHPQDG-------SCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPE 719
Query: 668 CMECKGPGAKNCTLC 682
C P + C
Sbjct: 720 TGACVCPPGHSGAPC 734
Score = 75.5 bits (184), Expect = 2e-13
Identities = 101/391 (25%), Positives = 135/391 (34%), Gaps = 85/391 (21%)
Query: 59 HCYKTCPEKTYSEAVECKACDSNCSSCD-QNGCYWCEEGFFLLGGSCVRKCGPGFYGDQE 117
HC ++CP+ T+ + + C +G C G+ G C C P YG
Sbjct: 390 HCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGY--TGPHCASLCPPDTYGVNC 447
Query: 118 MGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCH 177
C SC A P EC C+EG Q RG C G C+
Sbjct: 448 SARC-SCENA--IACSPIDGEC-VCKEGWQ--RGNCSVPCPPGTWG----------FSCN 491
Query: 178 SSCK-----TCNGSATLCTSCP--KGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAI 230
+SC+ C+ CT P GA+ C CP+G + E C C
Sbjct: 492 ASCQCAHEAVCSPQTGACTCTPGWHGAH-----CQLPCPKGQFG-------EGCASRCD- 538
Query: 231 CSGADLCK----KCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATN 286
C +D C +CQ Q G RC+ CPEG + + CS+ C TC+ T
Sbjct: 539 CDHSDGCDPVHGRCQCQAG----WMGARCHLSCPEGLWGVN-----CSNTC-TCKNGGT- 587
Query: 287 CHSCEGGHVLHHGV----CQENCPERHVAVEGVCKHCPEMCQDCIHEKTCKECMPEFFLH 342
C G V G CQ +C V C TC C+ +
Sbjct: 588 CLPENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNGTC-YCLAGWTGP 646
Query: 343 DDMCHQSCPRGFYADS-------HHCVPCHKDCLECSGPKADDCELCLESSWVLYDGLCL 395
D C Q CP G + ++ HH CH C P W + CL
Sbjct: 647 D--CSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICP----------LGWTGHH--CL 692
Query: 396 EECPAGTYYEKQTKECR-----DCHKSCLTC 421
E CP GT+ ++ C+ CH C
Sbjct: 693 EGCPLGTFGANCSQPCQCGPGEKCHPETGAC 723
Score = 70.1 bits (170), Expect = 8e-12
Identities = 86/340 (25%), Positives = 115/340 (33%), Gaps = 70/340 (20%)
Query: 59 HCYKTCPEKTYSEAVECKA---CDSNCSSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGD 115
HC CP TY V C A C++ + +G C+EG+ G+C C PG +G
Sbjct: 433 HCASLCPPDTY--GVNCSARCSCENAIACSPIDGECVCKEGW--QRGNCSVPCPPGTWGF 488
Query: 116 QEMGECESCHRA-CETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQ 174
C+ H A C TG +C G H +G+F +
Sbjct: 489 SCNASCQCAHEAVCSPQTG-----ACTCTPGWH-----GAHCQLPCPKGQFGEGCASRCD 538
Query: 175 PCHS-SCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSG 233
HS C +G C A + C SCP+G W NC+ C C
Sbjct: 539 CDHSDGCDPVHG------RCQCQAGWMGARCHLSCPEGLWG-------VNCSNTCT-CKN 584
Query: 234 ADLC----KKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHS 289
C C PG C C G Y +RC PC+ N + CH
Sbjct: 585 GGTCLPENGNCVCAPG----FRGPSCQRSCQPGRYG-----KRC-VPCKC--ANHSFCHP 632
Query: 290 CEGGHVLHHG----VCQENCPERHVAVEGVCKHCPEMCQDCIHEKTCK----ECMPEFFL 341
G G C + CP H ++C + CQ C H TC C+
Sbjct: 633 SNGTCYCLAGWTGPDCSQPCPPGHWG-----ENCAQTCQ-CHHGGTCHPQDGSCICPLGW 686
Query: 342 HDDMCHQSCPRGFY----ADSHHCVP---CHKDCLECSGP 374
C + CP G + + C P CH + C P
Sbjct: 687 TGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCP 726
Score = 55.1 bits (131), Expect = 3e-07
Identities = 80/340 (23%), Positives = 103/340 (30%), Gaps = 117/340 (34%)
Query: 461 CKP-CHVKCFHCMGPAEDQCQ--------------------------------------- 480
C P C +C H A +QCQ
Sbjct: 101 CVPLCAQECVHGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKS 160
Query: 481 -TCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHS-------------------SCRT- 519
C S L C++ C GYY RC CH SC
Sbjct: 161 GVCSCPSGLQPPNCLQPCTPGYYGPACQFRC-QCHGAPCDPQTGACFCPAERTGPSCDVS 219
Query: 520 ---------CEGRHSRQ----------CHSCRPGWFQLGKECLLQCREGYYADNSTGRCE 560
C HS Q SC PGW +G C L C EG++ N
Sbjct: 220 CSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGW--MGTICSLPCPEGFHGPN------ 271
Query: 561 RCNRSCKGCQGPRPTDCLSCDRFFFLLR-----SKGECHRSCPDHYYVEQSTQTCERCHP 615
C++ C+ G CDRF R + C CP + + +TC+ C P
Sbjct: 272 -CSQECRCHNGG------LCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCD-CAP 323
Query: 616 TCDQCKGKGALNCLSCVWSYHLMGGICTSD-CLVGEYRVGEGEKFNCEKCHE-SCMECKG 673
GA C+ + G CT C G Y + C++ H SC G
Sbjct: 324 DARCFPANGA-----CLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNG 378
Query: 674 PGAKNCTLCPANLVLHMDESHCLHCCNTSDPPSAQECCDC 713
C+ P LH +ES C + P QE C C
Sbjct: 379 ----ECSCLPGWAGLHCNES----CPQDTHGPGCQEHCLC 410
Score = 31.2 bits (69), Expect = 4.3
Identities = 25/95 (26%), Positives = 37/95 (38%), Gaps = 10/95 (10%)
Query: 60 CYKTCPEKTYSE--AVECKACDSNCSSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQ- 116
C + CP + E A C+ C + Q+G C G+ G C+ C G +G
Sbjct: 648 CSQPCPPGHWGENCAQTCQ-CHHGGTCHPQDGSCICPLGW--TGHHCLEGCPLGTFGANC 704
Query: 117 ----EMGECESCHRACETCTGPGHDECSSCQEGLQ 147
+ G E CH C P + C+ G+Q
Sbjct: 705 SQPCQCGPGEKCHPETGACVCPPGHSGAPCRIGIQ 739
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 115 bits (289), Expect = 1e-25
Identities = 170/690 (24%), Positives = 235/690 (34%), Gaps = 165/690 (23%)
Query: 60 CYKTCPEKTYSEAVECKACDSNCSSCDQ-NGCYWCEEGFFLLGGSCVRKCGPGFYGDQEM 118
C +TCP T+ + N +CD G C G + G +C C G+YG
Sbjct: 551 CNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPG--VSGTNCEDGCPKGYYGKHCR 608
Query: 119 GECE-----SCHRACETCTGPGHDECSSCQEGLQLLRGMCVHAT-KTQEEGKFWNDILRK 172
+C CHR C C GL G H T G ++ +
Sbjct: 609 KKCNCANRGRCHRLYGACL---------CDPGLY---GRFCHLTCPPWAFGPGCSEECQC 656
Query: 173 LQPCHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCT----EAC 228
+QP SC +GS SC G + C + C G + G + CT AC
Sbjct: 657 VQPHTQSCDKRDGSC----SCKAG--FRGERCQAECELGYF---GPGCWQACTCPVGVAC 707
Query: 229 AICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPC----RTCEGNA 284
SG + K+C P C +CP G++ + CSS C C G
Sbjct: 708 DSVSG-ECGKRC------PAGFQGEDCGQECPVGTFGVN-----CSSSCSCGGAPCHGVT 755
Query: 285 TNCHSCEGGHVLHHGVCQENCPERHVAVEGVCKHCPEMCQDCIHEKTCKE------CMPE 338
C C G C+ +CPE + C E+C C H C C+P
Sbjct: 756 GQCR-CPPGRTGED--CEADCPEGRWGL-----GCQEICPACQHAARCDPETGACLCLPG 807
Query: 339 FFLHDDMCHQSCPRGFY----------ADSHHCVPCHKDCLECSGPKADDCELCLES--- 385
F C CP G+Y A+ HC P C G C+ ++
Sbjct: 808 FV--GSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHW 865
Query: 386 ---------------SWVLYDGLCL-----------EECPAGTYYEKQTKECRDCHKSCL 419
S GLCL ++CP G + + C+ C
Sbjct: 866 GPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQ-CQHGAA 924
Query: 420 TCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQC 479
SG C TC G RG+ E P+ ++ D C C G A D
Sbjct: 925 CDHVSGAC-TCPAGW----RGTFC--EHACPAGFFGLD------CRSACNCTAGAACDAV 971
Query: 480 Q-TCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQL 538
+C + C + CP Y S CA C + +C+ H QCH C PGW +
Sbjct: 972 NGSCLCPAGRRGPRCAETCPAHTYGHNCSQACA-CFNGA-SCDPVHG-QCH-CAPGW--M 1025
Query: 539 GKECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCP 598
G CL C G Y DN C SC CQ D +S G C +CP
Sbjct: 1026 GPSCLQACPAGLYGDN-------CRHSCL-CQNGGTCDPVS-----------GHC--ACP 1064
Query: 599 DHYYVEQSTQTCER-CHPTCDQCKGKGALNCLS----------CVWSYHLMGGICTSDCL 647
+ + + CE+ C P + + + CL+ C+ G C S CL
Sbjct: 1065 EGW----AGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCL 1120
Query: 648 VGEYRVGEGEKFNC---EKCHESCMECKGP 674
G + ++ +C CH C+ P
Sbjct: 1121 RGWFGEACAQRCSCPPGAACHHVTGACRCP 1150
Score = 110 bits (275), Expect = 6e-24
Identities = 173/757 (22%), Positives = 226/757 (29%), Gaps = 202/757 (26%)
Query: 56 FDHHCYKTCPEKTY----SEAVEC-----KACDSNCSSCDQNGCYW-------CEEGFFL 99
+ C+ TCP + SE +C ++CD SC + CE G+F
Sbjct: 633 YGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFG 692
Query: 100 LG-----------------GSCVRKCGPGFYGDQEMGECESCHRACETCTGPGHDECSSC 142
G G C ++C GF G E C + C T G + SSC
Sbjct: 693 PGCWQACTCPVGVACDSVSGECGKRCPAGFQG-------EDCGQECPVGTF-GVNCSSSC 744
Query: 143 QEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSCKTCNGSATLCTSCPKGAYLLAQ 202
G PCH C CP G +
Sbjct: 745 SCG---------------------------GAPCHGVTGQCR--------CPPGR--TGE 767
Query: 203 ACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCK----KCQMQPGHPLFLHEGRCYSK 258
C + CP+G W C E C C A C C PG RC
Sbjct: 768 DCEADCPEGRWGL-------GCQEICPACQHAARCDPETGACLCLPG----FVGSRCQDV 816
Query: 259 CPEGSYAEDGICERCSSPCRTCEGNATNCHSCEGGHVLHHG----VCQENCPERHVAVEG 314
CP G Y C + C +C N +CH G G CQ C H +
Sbjct: 817 CPAGWYGPS-----CQTRC-SC-ANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPD- 868
Query: 315 VCKHCPEMCQDCIHEKTCKE----CMPEFFLHDDMCHQSCPRGFYADSHHCVPCHKDCLE 370
C C +C C+ E C Q CP+G + C + C
Sbjct: 869 ----CSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPG-----CEQRCQC 919
Query: 371 CSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKQTKECRDCHKSCLTCSSSGTCTTC 430
G D C CPAG + DC +C C++ C
Sbjct: 920 QHGAACDHVSGACTCPAGWRGTFCEHACPAGFF-------GLDCRSAC-NCTAGAACDAV 971
Query: 431 QKGLIMNPRG--SCMANEKCSPSEYWDEDAPGCKPCHVKCFH--CMGPAEDQCQTCPMNS 486
G + P G E C Y + C CF+ P QC P
Sbjct: 972 -NGSCLCPAGRRGPRCAETCPAHTYGHNCSQAC-----ACFNGASCDPVHGQCHCAPG-- 1023
Query: 487 LLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLG--KECLL 544
+ +C++ CP G Y D + C C + TC+ S C +C GW L KECL
Sbjct: 1024 -WMGPSCLQACPAGLYGDNCRHSCL-CQNG-GTCD-PVSGHC-ACPEGWAGLACEKECLP 1078
Query: 545 Q-----------CREGYYADNSTGRC--------ERCNRSC-KGCQGPRPTDCLSCDRFF 584
+ C G D TGRC ++C C +G G SC
Sbjct: 1079 RDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGA 1138
Query: 585 FLLRSKGE-----------CHRSCPDHYYVEQSTQTCE------RCHPTCDQCKGKGALN 627
G C ++CP + E Q C+ CHP C
Sbjct: 1139 ACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTC------- 1191
Query: 628 CLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFNC---EKCHESCMECKGPGAKNCTLCPA 684
SC YH G C C G Y G + C C + C+ P T C
Sbjct: 1192 --SCAAGYH--GPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNL 1247
Query: 685 NLVLHMDESHCLHCCNTSDPPSAQECCDCQDTTDECI 721
+C H C + C T C+
Sbjct: 1248 TCPQGRFGPNCTHVCGCGQGAA------CDPVTGTCL 1278
Score = 101 bits (251), Expect = 3e-21
Identities = 149/619 (24%), Positives = 202/619 (32%), Gaps = 170/619 (27%)
Query: 60 CYKTCPEKTYSEAVECKACDSNCSSCDQ-NGCYWCEEGFFLLGGSCVRKCGPGFYGDQEM 118
C +TCP TY N +SCD +G C G+ +G SC++ C G YGD
Sbjct: 986 CAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGW--MGPSCLQACPAGLYGDNCR 1043
Query: 119 GECESCHRACETCTGPGHDECSSCQEGLQL--------LRGMCVHATKTQEEGKFWNDIL 170
C C GH C GL +R C H+ G
Sbjct: 1044 HSC-LCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGG------- 1095
Query: 171 RKLQPCHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAI 230
C+ C CP G C S C +G + E C + C+
Sbjct: 1096 -----------LCDPHTGRCL-CPAG--WTGDKCQSPCLRGWFG-------EACAQRCSC 1134
Query: 231 CSGA---DLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNC 287
GA + C+ PG F G C CP GS+ ED C+ C+ C G C
Sbjct: 1135 PPGAACHHVTGACRCPPG---FTGSG-CEQACPPGSFGED-----CAQMCQ-CPGENPAC 1184
Query: 288 H------SCEGGHVLHHGVCQENCPERHVAVEGVCKHCPEMCQDCIHEKTCKECM----- 336
H SC G+ H CQ+ CP C ++C C++ +C
Sbjct: 1185 HPATGTCSCAAGY--HGPSCQQRCPPGRYG-----PGCEQLC-GCLNGGSCDAATGACRC 1236
Query: 337 PEFFLHDDMCHQSCPRGFYADSHHCVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLE 396
P FL D C+ +CP+G + + C C G D G CL
Sbjct: 1237 PTGFLGTD-CNLTCPQGRFGPN-----CTHVCGCGQGAACDPVT-----------GTCL- 1278
Query: 397 ECPAGTYYEKQTKECRD------CHKSCLTCSSSGTCT----TCQKGLIMNPRGSCMANE 446
CP G + + C C +C +C + G C +C GL R +A
Sbjct: 1279 -CPPGRAGVRCERGCPQNRFGVGCEHTC-SCRNGGLCHASNGSCSCGLGWTGRHCELA-- 1334
Query: 447 KCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADED 506
C P Y CH++C +C NS T C G+Y
Sbjct: 1335 -CPPGRYG-------AACHLEC------------SCHNNSTCEPATGTCRCGPGFYG--- 1371
Query: 507 SNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNSTGRC------- 559
+ CE H C PG+ G + L C+ G D +GRC
Sbjct: 1372 -----------QACE-------HPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFH 1413
Query: 560 -ERCNRSCK------------GCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQS 606
C R C+ C G P D ++ RS C+ C +
Sbjct: 1414 GHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSC 1473
Query: 607 TQTCE-----RCHPTCDQC 620
T C+ C P QC
Sbjct: 1474 TLHCDCGGGADCDPVSGQC 1492
Score = 88.2 bits (217), Expect = 3e-17
Identities = 160/700 (22%), Positives = 228/700 (32%), Gaps = 168/700 (24%)
Query: 102 GSCVRKCGPGFYGDQEMGECESCH---------RACETCTGPGHDECSS----CQEGLQL 148
GSC+ +C + + CE CH +ACE DEC++ C G
Sbjct: 253 GSCMHRCQVV----RGLARCE-CHVGYQLAADGKACEDV-----DECAAGLAQCAHGCLN 302
Query: 149 LRGM--CV-HATKTQEEGKFWNDILRKLQPCHSSCKTCNGSATLCTSCPKGAYLLAQACV 205
+G CV HA E G R +SC+ NG C G + +
Sbjct: 303 TQGSFKCVCHAG--YELGADGRQCYRIEMEIVNSCEANNGG------CSHGCSHTSAGPL 354
Query: 206 SSCPQGTWPSVRSGSCENCTEACAICSGADLCKK-CQMQPGHPLFLHEGRCYSK---CPE 261
+CP+G +C + + C+ + C++ C PG +E CY+ +
Sbjct: 355 CTCPRGYELDTDQRTCIDVDD----CADSPCCQQVCTNNPGG----YECGCYAGYRLSAD 406
Query: 262 GSYAEDGICERCSSPCRTCEGNATNCH-----SCEGGHVLHHGVCQENCPERHVAVEGVC 316
G ED + C+S CE + TN SCE G+ LH + C + +
Sbjct: 407 GCGCED--VDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHED--RRGCSPLEEPMVDLD 462
Query: 317 KHCPEMCQDCIHEKTCKECMPEFFLHDDMCHQSCPRGFYADSHHCVPCHKDCLECSGPKA 376
P + H ++ +P+ F DD+ A
Sbjct: 463 GELP-FVRPLPHIAVLQDELPQLFQDDDV-----------------------------GA 492
Query: 377 DDCELCLESSWVLYDG-LCLEECPAGTYYEKQTKECRDCHKSCLTCSSSGTCTTCQKGLI 435
D+ E L L + +CL++ DC +C C + GTC G
Sbjct: 493 DEEEAELRGEHTLTEKFVCLDDSFG-----------HDCSLTCDDCRNGGTCLLGLDGCD 541
Query: 436 MNPRG--SCMANEKCSPSEYWDEDAPGCKPCHVKCFHCM--GPAEDQCQTCPMNSLLLNT 491
P G + NE C P + K C C C G + C + T
Sbjct: 542 C-PEGWTGLICNETCPPDTFG-------KNCSFSC-SCQNGGTCDSVTGACRCPPGVSGT 592
Query: 492 TCVKDCPEGYYADE--------DSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGKECL 543
C CP+GYY + RC + +C G + R CH P W G C
Sbjct: 593 NCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPW-AFGPGCS 651
Query: 544 LQC------------REGYYADNSTGRCERCNRSCK-GCQGPRPTDCLSCDRFFFLLRSK 590
+C R+G + + R ERC C+ G GP +C
Sbjct: 652 EECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVS 711
Query: 591 GECHRSCPDHYYVEQSTQTCE------RCHPTCDQCKGKGALNCL-SCVWSYHLMGGICT 643
GEC + CP + E Q C C +C C G C G C
Sbjct: 712 GECGKRCPAGFQGEDCGQECPVGTFGVNCSSSC-SCGGAPCHGVTGQCRCPPGRTGEDCE 770
Query: 644 SDCLVGEYRVGEGEKFNCEKCHESCMECK-----GPGAKNCTLCPANLVLHMDESHCLHC 698
+DC G + +G C E C C+ P C P + S C
Sbjct: 771 ADCPEGRWGLG---------CQEICPACQHAARCDPETGACLCLPGFV-----GSRCQDV 816
Query: 699 CNTS-DPPSAQECCDCQDTTDECILRTSKVRPATEHFKTA 737
C PS Q C C + PAT H A
Sbjct: 817 CPAGWYGPSCQTRCSCAN--------DGHCHPATGHCSCA 848
Score = 47.4 bits (111), Expect = 6e-05
Identities = 52/189 (27%), Positives = 66/189 (34%), Gaps = 46/189 (24%)
Query: 59 HCYKTCPEKTYSEAVECKACDSNCSSCD-QNGCYWCEEGFFLLGGSCVRKCGPGFYGDQE 117
HC CP Y A + N S+C+ G C GF+ G +C C PGF+G
Sbjct: 1330 HCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFY--GQACEHPCPPGFHGAGC 1387
Query: 118 MGECESCHRA-CETCTG----PGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRK 172
G C H A C+ +G P C+ G E G F
Sbjct: 1388 QGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGC--------------EPGSFG------ 1427
Query: 173 LQPCHSSCKTCNGSAT------LCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTE 226
+ CH C C+G A LC CP G C C +G + +CT
Sbjct: 1428 -EGCHQRC-DCDGGAPCDPVTGLCL-CPPGR--SGATCNLDCRRGQFG-------PSCTL 1475
Query: 227 ACAICSGAD 235
C GAD
Sbjct: 1476 HCDCGGGAD 1484
Score = 44.7 bits (104), Expect = 4e-04
Identities = 72/323 (22%), Positives = 102/323 (31%), Gaps = 61/323 (18%)
Query: 426 TCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHC----MGPA----ED 477
T C +G + P + +CS S + C P + HC GP D
Sbjct: 106 TVLRCCRGWMQQPDEEGCLSAECSASLCFHGGR--CVPGSAQPCHCPPGFQGPRCQYDVD 163
Query: 478 QCQT----CPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQC----- 528
+C+T C + + + +C G+ DS C +S C G C
Sbjct: 164 ECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINS-CALGNGGCQHHCVQLTI 222
Query: 529 --HSCRPGWFQLGKECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFL 586
H C QCR G+ C R C G SC +
Sbjct: 223 TRHRC-------------QCRPGFQLQEDGRHCVR-RSPCANRNG-------SCMHRCQV 261
Query: 587 LRSKGECHRSCPDHYYVEQSTQTCE---RCHPTCDQC-----KGKGALNCLSCVWSYHLM 638
+R C C Y + + CE C QC +G+ C+ C Y L
Sbjct: 262 VRGLARCE--CHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCV-CHAGYEL- 317
Query: 639 GGICTSDCLVGEYRVGEGEKFNCEKCHESCME-CKGPGAKNCTLCPANLVLHMDESHCLH 697
G C YR+ +CE + C C A CP L D+ C+
Sbjct: 318 -GADGRQC----YRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCID 372
Query: 698 CCNTSDPPSAQECCDCQDTTDEC 720
+ +D P Q+ C EC
Sbjct: 373 VDDCADSPCCQQVCTNNPGGYEC 395
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 110 bits (276), Expect = 4e-24
Identities = 150/540 (27%), Positives = 198/540 (36%), Gaps = 137/540 (25%)
Query: 58 HHCYKTCPEKTYSEAVECKACDSNCSSCDQ--NGCYWCEEGFFLLGGSCVRKCGPGFYGD 115
HHC ++CP Y + + N + C GC C GF +G C C G YG
Sbjct: 388 HHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCT-CAPGF--MGEVCAVSCAAGTYGP 444
Query: 116 QEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQP 175
C SC+ TC+ P C+ C+EG Q L T G + +
Sbjct: 445 NCSSIC-SCNNG-GTCS-PVDGSCT-CKEGWQGL-----DCTLPCPSGTWGLN------- 488
Query: 176 CHSSCKTCNGSAT--LCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSG 233
C+ SC NG+A + SC L C CP GT+ NC+E C CS
Sbjct: 489 CNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGL-------NCSEHCD-CSH 540
Query: 234 ADLCKKCQMQPGHPLFLHEG---RCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSC 290
AD C GH L RC S CP G + + CS C SC
Sbjct: 541 AD---GCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPN-----CSVSC-----------SC 581
Query: 291 EGGHVLHHGVCQENCPERHVAVEGVCKHCPEMCQDCIHEKTCKECMPEFFLHDDMCHQSC 350
E G G C PE +G C EC P F +C + C
Sbjct: 582 ENG-----GSCS---PE-----DGSC-----------------ECAPGF--RGPLCQRIC 609
Query: 351 PRGFYADSHHCVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKQTKE 410
P GFY H C C+ S P +C E LC + C AG Y+ +
Sbjct: 610 PPGFYG--HGCAQPCPLCVHSSRPCHHISGIC-ECLPGFSGALCNQVC-AGGYFGQ---- 661
Query: 411 CRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCH--VKC 468
DC + C +C+++GTC+ GSC +C P + + C P C
Sbjct: 662 --DCAQLC-SCANNGTCSPID--------GSC----QCFPGWIGKDCSQACPPGFWGPAC 706
Query: 469 FHCMG-------PAED-QCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHS----- 515
FH AED C P + L C + CP ++ +D R C +
Sbjct: 707 FHACSCHNGASCSAEDGACHCTPGWTGLF---CTQRCPAAFFG-KDCGRVCQCQNGASCD 762
Query: 516 ------SCRT-CEGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNSTGRCERCNRSCKG 568
+CRT G+H Q C PG F G + L +C D+ TG C C+ KG
Sbjct: 763 HISGKCTCRTGFTGQHCEQ--RCAPGTFGYGCQQLCECMNNSTCDHVTGTC-YCSPGFKG 819
Score = 97.8 bits (242), Expect = 4e-20
Identities = 168/669 (25%), Positives = 222/669 (33%), Gaps = 137/669 (20%)
Query: 89 GCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQL 148
G C GF G C C PG +G C+ H A +C P EC C G
Sbjct: 159 GACVCAAGF--RGWRCEELCAPGTHGKGCQLPCQCRHGA--SCD-PRAGECL-CAPGYTG 212
Query: 149 LRGMCVHATKTQEEGKFWNDILRKLQPCHSSCKTCNGSATLCTSCPKGAYLLAQACVSSC 208
+ C G LR PC + TC+ C +CP G C C
Sbjct: 213 V--YCEELCPPGSHGAHCE--LRC--PCQNG-GTCHHITGEC-ACPPG--WTGAVCAQPC 262
Query: 209 PQGTWPSVRSGSCENCTEACAICSGAD---LCKKCQMQPGHPLFLHEGRCYSKCPEGSYA 265
P GT+ +NC++ C G + +C G+ RC +CP GS+
Sbjct: 263 PPGTFG-------QNCSQDCPCHHGGQCDHVTGQCHCTAGYM----GDRCQEECPFGSFG 311
Query: 266 EDGICERCSSPCRTCEGN----ATNCHSCEGGHVLHHGVCQEN-CPERHVAVEGVCKHCP 320
+CS C G T CE G+ CQE CPE + G CP
Sbjct: 312 F-----QCSQHCDCHNGGQCSPTTGACECEPGYKGPR--CQERLCPEG-LHGPGCTLPCP 363
Query: 321 EMCQDCI--HEKT-CKECMPEFFLHDDMCHQSCPRGFYADSHHCVPCHKDCLECSGPKAD 377
+ I H T C P + H C++SCP G+Y D C L C+
Sbjct: 364 CDADNTISCHPVTGACTCQPGWSGHH--CNESCPVGYYGDG-----CQ---LPCTCQNGA 413
Query: 378 DCEL----CLESSWVLYDGLCLEECPAGTYYEKQTKECRDCHKSCLTCSSSGTCTTCQKG 433
DC C + + + +C C AGTY +C C +C++ GTC+
Sbjct: 414 DCHSITGGCTCAPGFMGE-VCAVSCAAGTYGP-------NCSSIC-SCNNGGTCSPVD-- 462
Query: 434 LIMNPRGSCMANE-----KCS---PSEYWDEDAPGCKPCHVKCFHCMG----PAEDQCQT 481
GSC E C+ PS W + C+ C G P + C
Sbjct: 463 ------GSCTCKEGWQGLDCTLPCPSGTWGLN------CNESCTCANGAACSPIDGSCSC 510
Query: 482 CPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGKE 541
P L TC CP+G + S C H+ C+ C C GW G
Sbjct: 511 TPG---WLGDTCELPCPDGTFGLNCSEHCDCSHAD--GCDPVTGHCC--CLAGW--TGIR 561
Query: 542 CLLQCREGYYADNSTGRCERCNRSCK--GCQGPRPTDCLSCDRFFFLLRSKGECHRSCPD 599
C C G + N + C SC+ G P C F L C R CP
Sbjct: 562 CDSTCPPGRWGPNCSVSC-----SCENGGSCSPEDGSCECAPGFRGPL-----CQRICPP 611
Query: 600 HYYVEQSTQTCERCHPTCDQCKG-KGALNCLSCVWSYHLMGGICTSDCLVGEY------R 652
+Y Q C C + C G CL G +C C G +
Sbjct: 612 GFYGHGCAQPCPLCVHSSRPCHHISGICECLP-----GFSGALCNQVCAGGYFGQDCAQL 666
Query: 653 VGEGEKFNCEKCHESCMECKGPGAKNCT-LCPANLVLHMDESHCLHCCNTSDPPSAQECC 711
C SC G K+C+ CP C H C+ + S C
Sbjct: 667 CSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFW----GPACFHACSCHNGAS----C 718
Query: 712 DCQDTTDEC 720
+D C
Sbjct: 719 SAEDGACHC 727
Score = 49.7 bits (117), Expect = 1e-05
Identities = 75/317 (23%), Positives = 97/317 (30%), Gaps = 67/317 (21%)
Query: 447 KCSPSEYWDEDAPGCKP-CHVKCFH--CMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYA 503
+C P Y E C P C +C H C+ P TC C C ++
Sbjct: 87 QCCPGYY--ESGDFCIPLCTEECVHGRCVSP-----DTCHCEPGWGGPDCSSGCDSDHWG 139
Query: 504 DEDSNRC-----AHCH---SSCRTCEGRHSRQCHS-CRPGWFQLGKECLLQCREGYYADN 554
SNRC A C+ +C G +C C PG G + QCR G D
Sbjct: 140 PHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDP 199
Query: 555 STGRC--------ERCNRSC-KGCQGPRPTDCLSCDRFFFLLRSKGE-----------CH 594
G C C C G G C GE C
Sbjct: 200 RAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCA 259
Query: 595 RSCPDHYYVEQSTQTCERCH--PTCDQCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYR 652
+ CP + + +Q C CH CD G+ C + MG C +C G +
Sbjct: 260 QPCPPGTFGQNCSQDCP-CHHGGQCDHVTGQ-------CHCTAGYMGDRCQEECPFGSFG 311
Query: 653 VGEGEKFNCE---KCHESCMEC------KGPGAKNCTLCPANLVLHMDESHCLHCCNTSD 703
+ +C +C + C KGP + LCP LH C
Sbjct: 312 FQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQE-RLCPEG--LHGPG------CTLPC 362
Query: 704 PPSAQECCDCQDTTDEC 720
P A C T C
Sbjct: 363 PCDADNTISCHPVTGAC 379
Score = 33.5 bits (75), Expect = 0.86
Identities = 40/184 (21%), Positives = 62/184 (33%), Gaps = 49/184 (26%)
Query: 526 RQCHSCRPGWFQLGKECLLQCRE----GYYADNSTGRCERCNRSCKGCQGPRPTDCLSCD 581
R+ C PG+++ G C+ C E G T CE G GP
Sbjct: 83 RRRSQCCPGYYESGDFCIPLCTEECVHGRCVSPDTCHCE------PGWGGP--------- 127
Query: 582 RFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALNCL--SCVWSYHLMG 639
+C C ++ + C QC+ N + +CV + G
Sbjct: 128 ----------DCSSGCDSDHWGPHCSNRC--------QCQNGALCNPITGACVCAAGFRG 169
Query: 640 GICTSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGAKNCTLCPANLVLHMDE-----SH 694
C C G + G+G + C+ H + + P A C P ++ +E SH
Sbjct: 170 WRCEELCAPGTH--GKGCQLPCQCRHGASCD---PRAGECLCAPGYTGVYCEELCPPGSH 224
Query: 695 CLHC 698
HC
Sbjct: 225 GAHC 228
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 109 bits (273), Expect = 9e-24
Identities = 171/704 (24%), Positives = 226/704 (32%), Gaps = 146/704 (20%)
Query: 43 PVQKQIHLKCGNRFDHHCYKTCPEKTYSEAVECKACDSNCSSCDQ-NGCYWCEEGFFLLG 101
P+ H G R C C + TY + N ++CD G C G+ G
Sbjct: 162 PITGACHCAAGFR-GWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGY--TG 218
Query: 102 GSCVRKCGPGFYGDQEMGECESCHRA--CETCTGPGHDECSSCQEGLQLLRGMCVHATKT 159
C C PG +G Q C C C TG ECS C G M +
Sbjct: 219 AFCEDLCPPGKHGPQCEQRCP-CQNGGVCHHVTG----ECS-CPSGW-----MGTVCGQP 267
Query: 160 QEEGKFWNDILRKLQPCHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSG 219
EG+F + ++ Q CH+ TC+ + C P + C CP GT+ + +
Sbjct: 268 CPEGRFGKNCSQECQ-CHNG-GTCDAATGQCHCSPG---YTGERCQDECPVGTYGVLCAE 322
Query: 220 SCENCTEA--CAICSGADLCKKCQMQPGHPLFLHEGRCYSK-CPEGSYAEDGICERCSSP 276
+C+ C C SGA LC+ F E RC ++ CPEG Y GI +C
Sbjct: 323 TCQ-CVNGGKCYHVSGACLCEAG--------FAGE-RCEARLCPEGLY---GI--KCDKR 367
Query: 277 CRTCEGNATNCHSCEGGHVLHHG----VCQENCPERHVAVEGVCKHCPEMCQ-----DCI 327
C N +CH G G C E C + C ++C DC
Sbjct: 368 CPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYG-----EACQQICSCQNGADCD 422
Query: 328 HEKTCKECMPEFFLHDDMCHQSCPRGFYA----------DSHHCVPCHKDCLECSGPKAD 377
C P F D C CP G Y + C P C +G
Sbjct: 423 SVTGKCTCAPGFKGID--CSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGV 480
Query: 378 DCEL-CLESSWVL----------------YDGLCLEECPAGTYYEKQTKECRD------C 414
DC + C +W DG C C G EK C+D C
Sbjct: 481 DCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCT--CAPGWRGEKCELPCQDGTYGLNC 538
Query: 415 HKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCK-PCHVKCFHCMG 473
+ C CS + C P S + + W P C PC+ K
Sbjct: 539 AERC-DCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRW---GPNCSLPCYCKNGASCS 594
Query: 474 PAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRP 533
P + C+ P TTC + C G+Y S C C S C H C P
Sbjct: 595 PDDGICECAPG---FRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPC--HHITGLCDCLP 649
Query: 534 GWFQLGKECLLQCREGYYADNSTGRCE-----RCNRSCKGCQ------------------ 570
G+ G C C G + N G C CN + CQ
Sbjct: 650 GF--TGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAH 707
Query: 571 -GPRPTDCLSCDRFFFLLRSKGECH-----------RSCPDHYYVEQSTQTCE-RCHPTC 617
GP +C F GEC + CP +Y + C+ + C
Sbjct: 708 WGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADC 767
Query: 618 DQCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFNC 661
D G+ C MG C C G Y G + +C
Sbjct: 768 DHISGQ-------CTCRTGFMGRHCEQKCPSGTYGYGCRQICDC 804
Score = 70.5 bits (171), Expect = 6e-12
Identities = 74/286 (25%), Positives = 102/286 (35%), Gaps = 54/286 (18%)
Query: 59 HCYKTCPEKTYSEAVECKACDSNCSSCD-QNGCYWCEEGFFLLGGSCVRKCGPGFYGDQE 117
HC C E + N +SC +G C GF G +C R C PGFYG +
Sbjct: 567 HCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGF--RGTTCQRICSPGFYGHR- 623
Query: 118 MGECESCHRACETC---TGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQ 174
C + C C +GP H C +C + GK
Sbjct: 624 ------CSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGK---------- 667
Query: 175 PCHSSCKTCNGSAT---LCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAIC 231
C C TC + T + SC + C CP W +C NC A C
Sbjct: 668 NCAGIC-TCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTC-NCHNG-AFC 724
Query: 232 SGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCH--- 288
S D +C+ PG C +CP G Y +D C+ C+ C+ A H
Sbjct: 725 SAYD--GECKCTPGWTGLY----CTQRCPLGFYGKD-----CALICQ-CQNGADCDHISG 772
Query: 289 --SCEGGHVLHHGVCQENCPERHVAVEGVCKHCPEMCQDCIHEKTC 332
+C G + H C++ CP C ++C DC++ TC
Sbjct: 773 QCTCRTGFMGRH--CEQKCPSGTYGY-----GCRQIC-DCLNNSTC 810
>gi|33598931 scavenger receptor class F, member 1 isoform 3
precursor [Homo sapiens]
Length = 569
Score = 88.6 bits (218), Expect = 2e-17
Identities = 111/432 (25%), Positives = 149/432 (34%), Gaps = 98/432 (22%)
Query: 320 PEMCQD---CIHEKTCKECMPEFFLHDDMCHQSCPRGFYA-DSHHCVPCHKDCLECSGPK 375
P+ CQ C+ C+ C P FF C CP ++ D PCH +C P
Sbjct: 60 PDACQKDEVCVKPGLCR-CKPGFF--GAHCSSRCPGQYWGPDCRESCPCHPHG-QCE-PA 114
Query: 376 ADDCELCLESSWVLYDGLCLEECPAGTY--YEKQTKECR--------DCHKSCLTCSSSG 425
C+ C W C C G + + T C C + C +++
Sbjct: 115 TGACQ-CQADRW---GARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAA 170
Query: 426 TCTTCQKGLIMNP-----RGSCMANEKCSPSEYWDEDAPGCKP------CHVKCFHCMG- 473
C + P R S N SP E D C+P C +C G
Sbjct: 171 RCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQ-DSGRCACRPGWWGPECQQQCECVRGR 229
Query: 474 --PAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCH---------SSCRTCE- 521
A +C TCP C CP G + + ++ C C SC +CE
Sbjct: 230 CSAASGEC-TCPPG--FRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEP 286
Query: 522 GRHSRQCHS-CRPGWFQLGKECLLQC---REGYYADNSTGRCERCNRSCKGCQGPRPTDC 577
G + QC C PG F G+ C QC R G + TG C+RC+ G GPR
Sbjct: 287 GWNGTQCQQPCLPGTF--GESCEQQCPHCRHGEACEPDTGHCQRCD---PGWLGPR---- 337
Query: 578 LSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERC-HPTCDQCKGKGALNCLSCVWSYH 636
C CP + E TC C +CD G CV S
Sbjct: 338 ---------------CEDPCPTGTFGEDCGSTCPTCVQGSCDTVTG-------DCVCSAG 375
Query: 637 LMGGICTSDCLVGEYRVGEGEKFNCE----KCHESCMECK-GPGAKNCTLCPANLV---- 687
G C + C G + G CE CH C+ G G+++ L +LV
Sbjct: 376 YWGPSCNASCPAGFH--GNNCSVPCECPEGLCHPVSGSCQPGSGSRDTALIAGSLVPLLL 433
Query: 688 LHMDESHCLHCC 699
L + + C CC
Sbjct: 434 LFLGLACCACCC 445
Score = 75.5 bits (184), Expect = 2e-13
Identities = 94/434 (21%), Positives = 141/434 (32%), Gaps = 88/434 (20%)
Query: 194 PKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKK---------CQMQP 244
PKG ++ CV+S P ++ IC G D C+K C+ +P
Sbjct: 24 PKGQHV----CVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKP 79
Query: 245 GHPLFLHEGRCYSKCPEGSYAED----------GICERCSSPCRTCEGN--ATNCH-SCE 291
G C S+CP + D G CE + C+ C+ + C C
Sbjct: 80 G----FFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQ-CQADRWGARCEFPCA 134
Query: 292 GGHVLHHGVCQENCPERHVAVEGVCKHCPEMCQDCIHEKTCKECMPEFFLHDDMCHQSCP 351
G HG C H C CQ C++ + C
Sbjct: 135 CGP---HGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCS 191
Query: 352 RGFYADSHHCVPCHKDCLECS------GPKADDCELCLESSWVLYDGLCL---------- 395
+ + H PC +D C+ GP+ C+ G C
Sbjct: 192 ---FRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCPPGFRGARC 248
Query: 396 -EECPAGTYYEKQTKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYW 454
CPAG++ + C C + +G+C +C+ G + C P +
Sbjct: 249 ELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGW-----NGTQCQQPCLPGTFG 303
Query: 455 DEDAPGCKPCHVKCFHC-----MGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNR 509
+ C +C HC P CQ C L C CP G + ++ +
Sbjct: 304 ES-------CEQQCPHCRHGEACEPDTGHCQRCDPG--WLGPRCEDPCPTGTFGEDCGST 354
Query: 510 CAHC-HSSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNST-------GRCER 561
C C SC T G C C G++ G C C G++ +N + G C
Sbjct: 355 CPTCVQGSCDTVTG----DC-VCSAGYW--GPSCNASCPAGFHGNNCSVPCECPEGLCHP 407
Query: 562 CNRSCKGCQGPRPT 575
+ SC+ G R T
Sbjct: 408 VSGSCQPGSGSRDT 421
Score = 72.8 bits (177), Expect = 1e-12
Identities = 99/446 (22%), Positives = 140/446 (31%), Gaps = 96/446 (21%)
Query: 117 EMGECESCHRACETCTGPGHDECSSCQEGLQLLR-GMC--------VHATKTQEEGKFWN 167
E+ C + + CT P + +CQ+ ++ G+C H + ++ G++W
Sbjct: 38 ELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCS-SRCPGQYWG 96
Query: 168 DILRKLQPC--HSSCKTCNGSATL------------CTSCPKGAYLLAQACVSSCPQGTW 213
R+ PC H C+ G+ C P G A V C G W
Sbjct: 97 PDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRCDPATG-VCHCEPGWW 155
Query: 214 PSVRSGSCENCTEACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERC 273
S C+ C A A C A G C C G + RC
Sbjct: 156 SSTCRRPCQ-CNTAAARCEQA-----------------TGACV--CKPGWWG-----RRC 190
Query: 274 SSPCRTCEGNATNCHSCEGGHVLHHGVCQENCPERHVAVEGVCKHCPEMCQDCIHEKTCK 333
S C C G+ C G G C ++ V G C C
Sbjct: 191 SFRC-NCHGSP--CEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGEC---------- 237
Query: 334 ECMPEFFLHDDMCHQSCPRGFYADSHHCVPCHKDCLECS-----GPKADDCELCLESSWV 388
C P F C CP G H V C C C P CE C E W
Sbjct: 238 TCPPGF--RGARCELPCPAG-----SHGVQCAHSCGRCKHNEPCSPDTGSCESC-EPGW- 288
Query: 389 LYDGLCLEECPAGTYYEKQTKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKC 448
C + C GT+ E ++C C +G C C G + PR + C
Sbjct: 289 -NGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGW-LGPR----CEDPC 342
Query: 449 SPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSN 508
+ ++ C C G + C ++ +C CP G++ +
Sbjct: 343 PTGTFGEDCGSTCPTC------VQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGN---- 392
Query: 509 RCAHCHSSCRTCEGRHSRQCHSCRPG 534
+C C EG SC+PG
Sbjct: 393 ---NCSVPCECPEGLCHPVSGSCQPG 415
Score = 55.1 bits (131), Expect = 3e-07
Identities = 57/183 (31%), Positives = 70/183 (38%), Gaps = 27/183 (14%)
Query: 60 CYKTCPEKTYSE--AVECKACDSN--CSSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGD 115
C CP ++ A C C N CS D C CE G+ G C + C PG +G+
Sbjct: 248 CELPCPAGSHGVQCAHSCGRCKHNEPCSP-DTGSCESCEPGWN--GTQCQQPCLPGTFGE 304
Query: 116 QEMGECESCHR--ACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKL 173
+C C ACE TG C C G L C T G F D
Sbjct: 305 SCEQQCPHCRHGEACEPDTG----HCQRCDPGW--LGPRCEDPCPT---GTFGED----- 350
Query: 174 QPCHSSCKTC-NGSA-TLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAIC 231
C S+C TC GS T+ C A +C +SCP G + S CE C
Sbjct: 351 --CGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGLCHPV 408
Query: 232 SGA 234
SG+
Sbjct: 409 SGS 411
Score = 54.7 bits (130), Expect = 4e-07
Identities = 64/240 (26%), Positives = 88/240 (36%), Gaps = 58/240 (24%)
Query: 78 CDSNCSSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGECESCHRACETCTGPGHD 137
C+ + S C+Q+ G C C PG++G + +CE C +G
Sbjct: 194 CNCHGSPCEQDS------------GRCA--CRPGWWGPECQQQCECVRGRCSAASG---- 235
Query: 138 ECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHS--SCK---TCNGSATLCTS 192
EC +C G + R C G +Q HS CK C+ C S
Sbjct: 236 EC-TCPPGFRGAR--CELPCPAGSHG---------VQCAHSCGRCKHNEPCSPDTGSCES 283
Query: 193 CPKGAYLLAQACVSSCPQGTWPSVRSGSCENCT--EACAICSGADLCKKCQMQPGHPLFL 250
C G C C GT+ C +C EAC +G C++C P +L
Sbjct: 284 CEPG--WNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGH--CQRCD-----PGWL 334
Query: 251 HEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEGGHVLHHGV----CQENCP 306
RC CP G++ ED C S C TC +C + G V G C +CP
Sbjct: 335 GP-RCEDPCPTGTFGED-----CGSTCPTCVQG--SCDTVTGDCVCSAGYWGPSCNASCP 386
Score = 43.1 bits (100), Expect = 0.001
Identities = 29/92 (31%), Positives = 36/92 (39%), Gaps = 20/92 (21%)
Query: 60 CYKTCPEKTYSEAVECKACDSNCSSCDQNGCYW------CEEGFFLLGGSCVRKCGPGFY 113
C CP T+ E C S C +C Q C C G++ G SC C GF+
Sbjct: 338 CEDPCPTGTFGED-----CGSTCPTCVQGSCDTVTGDCVCSAGYW--GPSCNASCPAGFH 390
Query: 114 GDQEMGECESCHRACETCTGPGHDECSSCQEG 145
G+ +C CE G H SCQ G
Sbjct: 391 GN-------NCSVPCECPEGLCHPVSGSCQPG 415
>gi|33598929 scavenger receptor class F, member 1 isoform 1
precursor [Homo sapiens]
Length = 830
Score = 88.6 bits (218), Expect = 2e-17
Identities = 111/432 (25%), Positives = 149/432 (34%), Gaps = 98/432 (22%)
Query: 320 PEMCQD---CIHEKTCKECMPEFFLHDDMCHQSCPRGFYA-DSHHCVPCHKDCLECSGPK 375
P+ CQ C+ C+ C P FF C CP ++ D PCH +C P
Sbjct: 60 PDACQKDEVCVKPGLCR-CKPGFF--GAHCSSRCPGQYWGPDCRESCPCHPHG-QCE-PA 114
Query: 376 ADDCELCLESSWVLYDGLCLEECPAGTY--YEKQTKECR--------DCHKSCLTCSSSG 425
C+ C W C C G + + T C C + C +++
Sbjct: 115 TGACQ-CQADRW---GARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAA 170
Query: 426 TCTTCQKGLIMNP-----RGSCMANEKCSPSEYWDEDAPGCKP------CHVKCFHCMG- 473
C + P R S N SP E D C+P C +C G
Sbjct: 171 RCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQ-DSGRCACRPGWWGPECQQQCECVRGR 229
Query: 474 --PAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCH---------SSCRTCE- 521
A +C TCP C CP G + + ++ C C SC +CE
Sbjct: 230 CSAASGEC-TCPPG--FRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEP 286
Query: 522 GRHSRQCHS-CRPGWFQLGKECLLQC---REGYYADNSTGRCERCNRSCKGCQGPRPTDC 577
G + QC C PG F G+ C QC R G + TG C+RC+ G GPR
Sbjct: 287 GWNGTQCQQPCLPGTF--GESCEQQCPHCRHGEACEPDTGHCQRCD---PGWLGPR---- 337
Query: 578 LSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERC-HPTCDQCKGKGALNCLSCVWSYH 636
C CP + E TC C +CD G CV S
Sbjct: 338 ---------------CEDPCPTGTFGEDCGSTCPTCVQGSCDTVTG-------DCVCSAG 375
Query: 637 LMGGICTSDCLVGEYRVGEGEKFNCE----KCHESCMECK-GPGAKNCTLCPANLV---- 687
G C + C G + G CE CH C+ G G+++ L +LV
Sbjct: 376 YWGPSCNASCPAGFH--GNNCSVPCECPEGLCHPVSGSCQPGSGSRDTALIAGSLVPLLL 433
Query: 688 LHMDESHCLHCC 699
L + + C CC
Sbjct: 434 LFLGLACCACCC 445
Score = 75.5 bits (184), Expect = 2e-13
Identities = 94/434 (21%), Positives = 141/434 (32%), Gaps = 88/434 (20%)
Query: 194 PKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKK---------CQMQP 244
PKG ++ CV+S P ++ IC G D C+K C+ +P
Sbjct: 24 PKGQHV----CVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKP 79
Query: 245 GHPLFLHEGRCYSKCPEGSYAED----------GICERCSSPCRTCEGN--ATNCH-SCE 291
G C S+CP + D G CE + C+ C+ + C C
Sbjct: 80 G----FFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQ-CQADRWGARCEFPCA 134
Query: 292 GGHVLHHGVCQENCPERHVAVEGVCKHCPEMCQDCIHEKTCKECMPEFFLHDDMCHQSCP 351
G HG C H C CQ C++ + C
Sbjct: 135 CGP---HGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCS 191
Query: 352 RGFYADSHHCVPCHKDCLECS------GPKADDCELCLESSWVLYDGLCL---------- 395
+ + H PC +D C+ GP+ C+ G C
Sbjct: 192 ---FRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCPPGFRGARC 248
Query: 396 -EECPAGTYYEKQTKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYW 454
CPAG++ + C C + +G+C +C+ G + C P +
Sbjct: 249 ELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGW-----NGTQCQQPCLPGTFG 303
Query: 455 DEDAPGCKPCHVKCFHC-----MGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNR 509
+ C +C HC P CQ C L C CP G + ++ +
Sbjct: 304 ES-------CEQQCPHCRHGEACEPDTGHCQRCDPG--WLGPRCEDPCPTGTFGEDCGST 354
Query: 510 CAHC-HSSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNST-------GRCER 561
C C SC T G C C G++ G C C G++ +N + G C
Sbjct: 355 CPTCVQGSCDTVTG----DC-VCSAGYW--GPSCNASCPAGFHGNNCSVPCECPEGLCHP 407
Query: 562 CNRSCKGCQGPRPT 575
+ SC+ G R T
Sbjct: 408 VSGSCQPGSGSRDT 421
Score = 72.8 bits (177), Expect = 1e-12
Identities = 99/446 (22%), Positives = 140/446 (31%), Gaps = 96/446 (21%)
Query: 117 EMGECESCHRACETCTGPGHDECSSCQEGLQLLR-GMC--------VHATKTQEEGKFWN 167
E+ C + + CT P + +CQ+ ++ G+C H + ++ G++W
Sbjct: 38 ELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCS-SRCPGQYWG 96
Query: 168 DILRKLQPC--HSSCKTCNGSATL------------CTSCPKGAYLLAQACVSSCPQGTW 213
R+ PC H C+ G+ C P G A V C G W
Sbjct: 97 PDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRCDPATG-VCHCEPGWW 155
Query: 214 PSVRSGSCENCTEACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERC 273
S C+ C A A C A G C C G + RC
Sbjct: 156 SSTCRRPCQ-CNTAAARCEQA-----------------TGACV--CKPGWWG-----RRC 190
Query: 274 SSPCRTCEGNATNCHSCEGGHVLHHGVCQENCPERHVAVEGVCKHCPEMCQDCIHEKTCK 333
S C C G+ C G G C ++ V G C C
Sbjct: 191 SFRC-NCHGSP--CEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGEC---------- 237
Query: 334 ECMPEFFLHDDMCHQSCPRGFYADSHHCVPCHKDCLECS-----GPKADDCELCLESSWV 388
C P F C CP G H V C C C P CE C E W
Sbjct: 238 TCPPGF--RGARCELPCPAG-----SHGVQCAHSCGRCKHNEPCSPDTGSCESC-EPGW- 288
Query: 389 LYDGLCLEECPAGTYYEKQTKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKC 448
C + C GT+ E ++C C +G C C G + PR + C
Sbjct: 289 -NGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGW-LGPR----CEDPC 342
Query: 449 SPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSN 508
+ ++ C C G + C ++ +C CP G++ +
Sbjct: 343 PTGTFGEDCGSTCPTC------VQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGN---- 392
Query: 509 RCAHCHSSCRTCEGRHSRQCHSCRPG 534
+C C EG SC+PG
Sbjct: 393 ---NCSVPCECPEGLCHPVSGSCQPG 415
Score = 55.1 bits (131), Expect = 3e-07
Identities = 57/183 (31%), Positives = 70/183 (38%), Gaps = 27/183 (14%)
Query: 60 CYKTCPEKTYSE--AVECKACDSN--CSSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGD 115
C CP ++ A C C N CS D C CE G+ G C + C PG +G+
Sbjct: 248 CELPCPAGSHGVQCAHSCGRCKHNEPCSP-DTGSCESCEPGWN--GTQCQQPCLPGTFGE 304
Query: 116 QEMGECESCHR--ACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKL 173
+C C ACE TG C C G L C T G F D
Sbjct: 305 SCEQQCPHCRHGEACEPDTG----HCQRCDPGW--LGPRCEDPCPT---GTFGED----- 350
Query: 174 QPCHSSCKTC-NGSA-TLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAIC 231
C S+C TC GS T+ C A +C +SCP G + S CE C
Sbjct: 351 --CGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGLCHPV 408
Query: 232 SGA 234
SG+
Sbjct: 409 SGS 411
Score = 54.7 bits (130), Expect = 4e-07
Identities = 64/240 (26%), Positives = 88/240 (36%), Gaps = 58/240 (24%)
Query: 78 CDSNCSSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGECESCHRACETCTGPGHD 137
C+ + S C+Q+ G C C PG++G + +CE C +G
Sbjct: 194 CNCHGSPCEQDS------------GRCA--CRPGWWGPECQQQCECVRGRCSAASG---- 235
Query: 138 ECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHS--SCK---TCNGSATLCTS 192
EC +C G + R C G +Q HS CK C+ C S
Sbjct: 236 EC-TCPPGFRGAR--CELPCPAGSHG---------VQCAHSCGRCKHNEPCSPDTGSCES 283
Query: 193 CPKGAYLLAQACVSSCPQGTWPSVRSGSCENCT--EACAICSGADLCKKCQMQPGHPLFL 250
C G C C GT+ C +C EAC +G C++C P +L
Sbjct: 284 CEPG--WNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGH--CQRCD-----PGWL 334
Query: 251 HEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEGGHVLHHGV----CQENCP 306
RC CP G++ ED C S C TC +C + G V G C +CP
Sbjct: 335 GP-RCEDPCPTGTFGED-----CGSTCPTCVQG--SCDTVTGDCVCSAGYWGPSCNASCP 386
Score = 43.1 bits (100), Expect = 0.001
Identities = 29/92 (31%), Positives = 36/92 (39%), Gaps = 20/92 (21%)
Query: 60 CYKTCPEKTYSEAVECKACDSNCSSCDQNGCYW------CEEGFFLLGGSCVRKCGPGFY 113
C CP T+ E C S C +C Q C C G++ G SC C GF+
Sbjct: 338 CEDPCPTGTFGED-----CGSTCPTCVQGSCDTVTGDCVCSAGYW--GPSCNASCPAGFH 390
Query: 114 GDQEMGECESCHRACETCTGPGHDECSSCQEG 145
G+ +C CE G H SCQ G
Sbjct: 391 GN-------NCSVPCECPEGLCHPVSGSCQPG 415
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 78.2 bits (191), Expect = 3e-14
Identities = 124/513 (24%), Positives = 166/513 (32%), Gaps = 134/513 (26%)
Query: 277 CRTCEG-NATNCHSCEGGH-----VLHHGVCQENCPERHVA---VEGVCKHCPEMCQDCI 327
C +G T+C SC G+ +L G+CQ H A V GVC C +
Sbjct: 709 CECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECNVHGVCIACAHNTTG-V 767
Query: 328 HEKTCKECMPEFFLHDDMCHQSCPRGFYADSHHCVPCHKDCLECSGPKADDCELC----L 383
H C++C+P F+ RG D C PC S + C L +
Sbjct: 768 H---CEQCLPGFYGEPS-------RGTPGD---CQPCACPLTIASNNFSPTCHLNDGDEV 814
Query: 384 ESSWVL--YDGLCLEECPAGTYYEKQTKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGS 441
W Y G E C G YY T +SC+ C SG
Sbjct: 815 VCDWCAPGYSGAWCERCADG-YYGNPTVP----GESCVPCDCSGNV-------------- 855
Query: 442 CMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAED-QCQTCPMNSLLLNTTCVKDCPEG 500
PSE A C +C C+G + C+ C +G
Sbjct: 856 -------DPSE-----AGHCDSVTGECLKCLGNTDGAHCERCA---------------DG 888
Query: 501 YYADEDSNRCAHCHSSCRTCE----GRHSRQCH------SCRPGWFQLGKECLLQCREGY 550
+Y D A +CR CE G HS CH C+P G++C QC GY
Sbjct: 889 FYGD------AVTAKNCRACECHVKGSHSAVCHLETGLCDCKPN--VTGQQCD-QCLHGY 939
Query: 551 YADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQT- 609
Y +S C CN S G TD C + + C R Y + + T
Sbjct: 940 YGLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKR--CDRCAHGFYAYQDGSCTP 997
Query: 610 --CERCHPTCDQCKGKGALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFNCEKC--- 664
C TCD G+ CV H G C +C G + G + C+ C
Sbjct: 998 CDCPHTQNTCDPETGE-------CVCPPHTQGVKC-EECEDGHW--GYDAEVGCQACNCS 1047
Query: 665 -----HESC------MECKGP-GAKNCTLCPANLVLHMDESHCLHCCNTSDPPSAQEC-- 710
H C +CK G + C C + D C+ C S C
Sbjct: 1048 LVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLG---YRDFPDCVPCDCDLRGTSGDACNL 1104
Query: 711 ----CDCQDTTDECILRTSKVRPATEHFKTALF 739
C C + T C + + P + F
Sbjct: 1105 EQGLCGCVEETGACPCKENVFGPQCNECREGTF 1137
Score = 55.8 bits (133), Expect = 2e-07
Identities = 104/488 (21%), Positives = 153/488 (31%), Gaps = 127/488 (26%)
Query: 78 CDSNCSSCDQNG-CYWCEEGFFLLGGSCVRKCGPGFYGDQEM---GECESCHRACE-TCT 132
C + + C+ +G C C G C +C PGFYG+ G+C+ C AC T
Sbjct: 744 CHGHAAECNVHGVCIACAHN--TTGVHC-EQCLPGFYGEPSRGTPGDCQPC--ACPLTIA 798
Query: 133 GPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSCKTCNGSATLCTS 192
+G +++ C S C
Sbjct: 799 SNNFSPTCHLNDGDEVVCDWCAPGY----------------------------SGAWCER 830
Query: 193 CPKGAY----LLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKKCQMQPGHPL 248
C G Y + ++CV G +G C++ T C C G
Sbjct: 831 CADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNT------------- 877
Query: 249 FLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHS--CEGGHVLHHGVCQ---- 302
+G +C +G Y + + CR CE + HS C L G+C
Sbjct: 878 ---DGAHCERCADGFYGDAVTAKN----CRACECHVKGSHSAVCH----LETGLCDCKPN 926
Query: 303 ------ENCPERHVAVEG--VCKHC-----PEMCQDCIHEKTCKECMPEFFLHDDMCHQS 349
+ C + ++ C+ C + C E C C+P + C +
Sbjct: 927 VTGQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDEGQC-HCVPG--VAGKRCDR- 982
Query: 350 CPRGFYA-DSHHCVPCHKDCLECSG---PKADDCELCLESSWVLYDGLCLEECPAGTYYE 405
C GFYA C PC DC P+ +C +C + G+ EEC G +
Sbjct: 983 CAHGFYAYQDGSCTPC--DCPHTQNTCDPETGEC-VCPPHT----QGVKCEECEDGHWGY 1035
Query: 406 KQTKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEK-----CSPSEYWDEDAPG 460
C+ C+ S L S+ C G C K C D P
Sbjct: 1036 DAEVGCQACNCS-LVGSTHHRCDVV--------TGHCQCKSKFGGRACDQCSLGYRDFPD 1086
Query: 461 CKPCHVKCFHCMGPA----------EDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSN-- 508
C PC G A ++ CP + C +C EG +A N
Sbjct: 1087 CVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQC-NECREGTFALRADNPL 1145
Query: 509 RCAHCHSS 516
C+ C S
Sbjct: 1146 GCSPCFCS 1153
Score = 55.5 bits (132), Expect = 2e-07
Identities = 109/484 (22%), Positives = 158/484 (32%), Gaps = 110/484 (22%)
Query: 128 CETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSCKTCNGSA 187
CE G C SC G + G+ + I + + CH CN
Sbjct: 709 CECPQGYTGTSCESCLSGYYRVDGI------------LFGGICQPCE-CHGHAAECNVHG 755
Query: 188 TLCTSCPKGAYLLAQACVSSCPQGTW--PSVRS-GSCENCTEACAICSGADLCKKCQMQP 244
+C +C A+ C G + PS + G C+ C I S + C +
Sbjct: 756 -VCIAC---AHNTTGVHCEQCLPGFYGEPSRGTPGDCQPCACPLTIASN-NFSPTCHLND 810
Query: 245 GHPLFL------HEGRCYSKCPEGSY---------------------AEDGICERCSSPC 277
G + + G +C +G Y +E G C+ + C
Sbjct: 811 GDEVVCDWCAPGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGEC 870
Query: 278 RTCEGNA--TNCHSCEGGHVLHHGVCQENCPERHVAVEG----VCKHCPEMCQDCIHEKT 331
C GN +C C G V +NC V+G VC +C DC T
Sbjct: 871 LKCLGNTDGAHCERCADGFY-GDAVTAKNCRACECHVKGSHSAVCHLETGLC-DCKPNVT 928
Query: 332 CKECMPEFFLHDDMCHQSCPRGFYA--DSHHCVPCHKDCLECSGPKADDCELCLESSWVL 389
++C C G+Y H C PC+ +G +D C E
Sbjct: 929 GQQC------------DQCLHGYYGLDSGHGCRPCN---CSVAGSVSDGCTD--EGQCHC 971
Query: 390 YDGLCLEECP--AGTYYEKQTKECR--DCHKSCLTCS-SSGTCTTCQKGLIMNPRGSCMA 444
G+ + C A +Y Q C DC + TC +G C + P +
Sbjct: 972 VPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQNTCDPETGEC-------VCPPHTQGVK 1024
Query: 445 NEKCSPSEYWDEDAP-GCKPC--------HVKCF----HCMGPAEDQCQTCPMNSLLLNT 491
E+C +W DA GC+ C H +C HC ++ + C SL
Sbjct: 1025 CEECEDG-HWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRD 1083
Query: 492 --TCVK-DCPEGYYADEDSNR------CAHCHSSCRTCEGRHSRQCHSCRPGWFQLGKEC 542
CV DC + + N C +C E QC+ CR G F L +
Sbjct: 1084 FPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADN 1143
Query: 543 LLQC 546
L C
Sbjct: 1144 PLGC 1147
Score = 51.2 bits (121), Expect = 4e-06
Identities = 73/303 (24%), Positives = 105/303 (34%), Gaps = 58/303 (19%)
Query: 50 LKC-GNRFDHHCYKTCPEKTYSEAV---ECKACDSNCSSCDQNGCY----WCEEGFFLLG 101
LKC GN HC + C + Y +AV C+AC+ + C+ C+ + G
Sbjct: 871 LKCLGNTDGAHCER-CADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTG 929
Query: 102 GSCVRKCGPGFYGDQEMGECESCH-----RACETCTGPGHDECSSCQEGLQLLRGMCVHA 156
C +C G+YG C C+ + CT G C G + R C H
Sbjct: 930 QQC-DQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDR--CAHG 986
Query: 157 TKTQEEGKFWNDILRKLQPCH--SSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWP 214
++G PC + TC+ C CP + C C G W
Sbjct: 987 FYAYQDG--------SCTPCDCPHTQNTCDPETGECV-CP--PHTQGVKC-EECEDGHWG 1034
Query: 215 SVRSGSCENCTEACAICSGADLCKKCQMQPGHPLFLHE--GRCYSKCPEGSYAEDGICER 272
C+ C C++ +C + GH + GR +C G Y + C
Sbjct: 1035 YDAEVGCQACN--CSLVGSTH--HRCDVVTGHCQCKSKFGGRACDQCSLG-YRDFPDCVP 1089
Query: 273 CSSPCRTCEGNATNCHSCEGGHVLHHGVCQENCPERHVAVEGVCKHCPEMCQDCIHEKTC 332
C R G+A N L G+C C E A CP C++ + C
Sbjct: 1090 CDCDLRGTSGDACN---------LEQGLC--GCVEETGA-------CP--CKENVFGPQC 1129
Query: 333 KEC 335
EC
Sbjct: 1130 NEC 1132
Score = 41.2 bits (95), Expect = 0.004
Identities = 40/163 (24%), Positives = 59/163 (36%), Gaps = 22/163 (13%)
Query: 176 CHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTE-ACAICSGA 234
C++ TC+ + C +C G C C G + V +GS +C AC A
Sbjct: 1405 CNNHSDTCDPNTGKCLNC--GDNTAGDHC-DVCTSGYYGKV-TGSASDCALCACPHSPPA 1460
Query: 235 DLCKKCQMQPGHP------LFLHEGRCYSKCPEGSYAED----GICERCSSPCRTCEGNA 284
C ++ H L +EG+ +C Y G C++C C
Sbjct: 1461 SFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCD--CNPHGSVH 1518
Query: 285 TNCHSCEGGHVLHHGV----CQENCPERHVAVEGVCKHCPEMC 323
+C G V G C E C RH+ +E C C + C
Sbjct: 1519 GDCDRTSGQCVCRLGASGLRCDE-CEPRHILMETDCVSCDDEC 1560
Score = 39.7 bits (91), Expect = 0.012
Identities = 63/263 (23%), Positives = 92/263 (34%), Gaps = 50/263 (19%)
Query: 392 GLCL-----EECPAGTYYEKQTKECRD--CHKSCLTCSSSGTCTTCQKGLIM--NPRGSC 442
G+C+ CP +K +C C +SC C + G + N +C
Sbjct: 268 GMCICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEAC 327
Query: 443 MANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQ--CQTCPMNSLLLNTTCVKDCPEG 500
+ K Y+DE K K + G C C N++ +N + C +G
Sbjct: 328 NCHNKAKDC-YYDESVAKQK----KSLNTAGQFRGGGVCINCLQNTMGINC---ETCIDG 379
Query: 501 YYADE-----DSNRCAHCH-------SSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCRE 548
YY + C C+ SS + HS + +PG +C C+E
Sbjct: 380 YYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPG------QC--PCKE 431
Query: 549 GYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQ 608
GY + +C+RC K PT C+SC S C C VE +
Sbjct: 432 GYTGE----KCDRCQLGYKDY----PT-CVSCGCNPVGSASDEPCTGPCVCKENVEG--K 480
Query: 609 TCERCHPTCDQCKGKGALNCLSC 631
C+RC P K K C C
Sbjct: 481 ACDRCKPGFYNLKEKNPRGCSEC 503
Score = 37.4 bits (85), Expect = 0.059
Identities = 63/251 (25%), Positives = 79/251 (31%), Gaps = 75/251 (29%)
Query: 398 CPAGTYYEKQTKECRDC----HKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEY 453
CP GT C+DC H+ L S PR CS + +
Sbjct: 1364 CPPGTV----GFSCQDCAPGYHRGKLPAGSD-----------RGPRPLVAPCVPCSCNNH 1408
Query: 454 WDEDAPGCKPCHVKCFHCM-GPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAH 512
D C P KC +C A D C C T DC CA
Sbjct: 1409 SDT----CDPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCA----------LCAC 1454
Query: 513 CHSS----CRTC--EGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNSTGRCERCNRSC 566
HS TC EG H +C +C G+ EG + CERC+ S
Sbjct: 1455 PHSPPASFSPTCVLEGDHDFRCDACLLGY------------EGKH-------CERCSSSY 1495
Query: 567 KGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPT---CDQCKGK 623
G C CD G H C S Q R + CD+C+ +
Sbjct: 1496 YGNPQTPGGSCQKCD-----CNPHGSVHGDCD-----RTSGQCVCRLGASGLRCDECEPR 1545
Query: 624 GAL---NCLSC 631
L +C+SC
Sbjct: 1546 HILMETDCVSC 1556
Score = 35.8 bits (81), Expect = 0.17
Identities = 55/274 (20%), Positives = 89/274 (32%), Gaps = 66/274 (24%)
Query: 308 RHVAVEGVCKHCPEMCQDCIHEKTCK--ECMPEFFLHDDMCHQSCPRGFYADSHHCVPCH 365
+ ++V G+C C C ++T K +C E + C++ CP +H P
Sbjct: 262 KDISVGGMCI-CYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCP------GYHQQPWR 314
Query: 366 KDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKQTKECRDCHKS-------- 417
+ + CE C C + Y E K+ + + +
Sbjct: 315 PGTVS----SGNTCEACN----------CHNKAKDCYYDESVAKQKKSLNTAGQFRGGGV 360
Query: 418 CLTCSSSG---TCTTCQKGLIMNPRGSCMANEKCSP-------------------SEYWD 455
C+ C + C TC G + S +E C P S+ +
Sbjct: 361 CINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHN 420
Query: 456 EDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTTCVKDC-PEGYYADEDSNRCAHCH 514
PG PC G ++C C + T C P G +DE C
Sbjct: 421 GKQPGQCPCKE------GYTGEKCDRCQLGYKDYPTCVSCGCNPVGSASDEP------CT 468
Query: 515 SSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCRE 548
C E + C C+PG++ L ++ C E
Sbjct: 469 GPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSE 502
>gi|143770880 laminin, beta 4 [Homo sapiens]
Length = 1761
Score = 78.2 bits (191), Expect = 3e-14
Identities = 108/442 (24%), Positives = 150/442 (33%), Gaps = 94/442 (21%)
Query: 250 LHEGRCYSKC-PEGSYAEDGICERCSSPCRTCEGNATN--CHSCEGGH--VLHHGVCQEN 304
LH+G KC P+GS C R C+ C+ C C G + HHG +
Sbjct: 762 LHDGAVACKCHPQGSVGSS--CSRLGGQCQ-CKPLVVGRCCDRCSTGSYDLGHHGCHPCH 818
Query: 305 CP---ERHVAVEGVCKHCPEMCQDCIHEKTCKECMPEFFLHDDMCHQSCPRGFYADSHHC 361
C + + V CP C + + C C+ +F CH CP +A+ C
Sbjct: 819 CHPQGSKDTVCDQVTGQCP--CHGEVSGRRCDRCLAGYFGFPS-CHP-CPCNRFAEL--C 872
Query: 362 VPCHKDCLECSG-PKADDCELCLE-------SSWVLYDGLCLEECPAGTYYEK---QTKE 410
P C C G +CE C++ S LC ++ + Y+ Q
Sbjct: 873 DPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLW 932
Query: 411 CRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWD-EDAPGCKPCHVKCF 469
D +CL + C C G NPR S + C+ + D D C +C
Sbjct: 933 SSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECL 992
Query: 470 HCMGPAED-QCQTCPMNSL--LLNTTCVK-----------DCP----------------- 498
C+ + CQ C LN TC + +CP
Sbjct: 993 RCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPC 1052
Query: 499 -------------EGYYADEDSNRCAHCHSSCRTCEGRHSRQCHS---CRPGWFQLGKEC 542
+GY+ C C RT + H Q C+ G+ GK C
Sbjct: 1053 LPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYG--GKRC 1110
Query: 543 LLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLR-----SKGECHRSC 597
+C+E YY D GRC C+ + G Q P CD + R S C R
Sbjct: 1111 S-ECQENYYGD-PPGRCIPCDCNRAGTQKP------ICDPDTGMCRCREGVSGQRCDRCA 1162
Query: 598 PDHYYVEQSTQTCERCHPTCDQ 619
H Q TC +CH DQ
Sbjct: 1163 RGH---SQEFPTCLQCHLCFDQ 1181
Score = 34.7 bits (78), Expect = 0.39
Identities = 55/237 (23%), Positives = 74/237 (31%), Gaps = 47/237 (19%)
Query: 77 ACDSNCSSCDQNGCYW----CEEGFFLLGGSCVRKCGPGFYGDQEMGECESCHRACETCT 132
AC++N D C C G+ + C PG YG C C +C
Sbjct: 971 ACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQLCKPGHYGSALNQTCRRC-----SCH 1025
Query: 133 GPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSCKTC-NGSATLCT 191
G C G G C+ P +C N + C
Sbjct: 1026 ASGVSP-MECPPG----GGACL------------------CDPVTGACPCLPNVTGLACD 1062
Query: 192 SCPKGAYLL--AQACVS-SCPQGTWPSVRSGSCENCTE--ACAICSGADLCKKCQMQ-PG 245
C G + L + C S C T +S C+ T C + G C +CQ G
Sbjct: 1063 RCADGYWNLVPGRGCQSCDCDPRT---SQSSHCDQLTGQCPCKLGYGGKRCSECQENYYG 1119
Query: 246 HPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEG-NATNCHSCEGGHVLHHGVC 301
P GRC + + IC+ + CR EG + C C GH C
Sbjct: 1120 DP----PGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARGHSQEFPTC 1172
>gi|205360958 cysteine-rich with EGF-like domains 2 isoform b [Homo
sapiens]
Length = 353
Score = 75.9 bits (185), Expect = 2e-13
Identities = 62/233 (26%), Positives = 81/233 (34%), Gaps = 51/233 (21%)
Query: 414 CHKSCLTCSSSGT----CTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCF 469
C K+ C S GT C CQ G + C N CS D C+ CH
Sbjct: 120 CVKTLKVCCSPGTYGPDCLACQGG----SQRPCSGNGHCSGDGSRQGDG-SCR-CH---- 169
Query: 470 HCMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYA---DEDSNRCAHCHSSCRTCEGRHSR 526
MG C DC +GY++ +E + C C SC+TC G +R
Sbjct: 170 --MGYQGPLCT---------------DCMDGYFSSLRNETHSICTACDESCKTCSGLTNR 212
Query: 527 QCHSCRPGWFQLGKECL---------LQCREGYYADNSTG--RCERCNRSCKGCQGPRPT 575
C C GW C+ C + N+ G CE C+ SC GC G P
Sbjct: 213 DCGECEVGWVLDEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPG 272
Query: 576 DCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALNC 628
+C C + H C D + +TC R + C G C
Sbjct: 273 NCKEC------ISGYAREHGQCADVDECSLAEKTCVRKNENCYNTPGSYVCVC 319
Score = 62.0 bits (149), Expect = 2e-09
Identities = 61/217 (28%), Positives = 81/217 (37%), Gaps = 42/217 (19%)
Query: 493 CVKD----CPEGYYADEDSNRCAHCHSSCRT-------CEGRHSRQCH-SCRPGWFQLGK 540
CVK C G Y + C C + C G SRQ SCR G
Sbjct: 120 CVKTLKVCCSPGTYGPD----CLACQGGSQRPCSGNGHCSGDGSRQGDGSCRCHMGYQGP 175
Query: 541 ECLLQCREGYYAD--NSTGR-CERCNRSCKGCQGPRPTDCLSCDRFFFLLRSK----GEC 593
C C +GY++ N T C C+ SCK C G DC C+ + L EC
Sbjct: 176 LCT-DCMDGYFSSLRNETHSICTACDESCKTCSGLTNRDCGECEVGWVLDEGACVDVDEC 234
Query: 594 HRSCPDHYYVE-----QSTQTCERCHPTCDQCKGKGALNCLSCVWSYHLMGGIC--TSDC 646
P + + TCE C +C C G+G NC C+ Y G C +C
Sbjct: 235 AAEPPPCSAAQFCKNANGSYTCEECDSSCVGCTGEGPGNCKECISGYAREHGQCADVDEC 294
Query: 647 LVGEYRVGEGEKFNCEKCHESCMECKGPGAKNCTLCP 683
+ E C + +E+C PG+ C +CP
Sbjct: 295 SLAEK--------TCVRKNENCYNT--PGSYVC-VCP 320
Score = 60.8 bits (146), Expect = 5e-09
Identities = 67/286 (23%), Positives = 94/286 (32%), Gaps = 96/286 (33%)
Query: 56 FDHHCYKT----CPEKTYSEAVECKACDSNCSS-CDQNGCYWCEEGFFLLGGSCVRKCGP 110
F+ C KT C TY +C AC C NG + +G GSC +C
Sbjct: 116 FEWFCVKTLKVCCSPGTYGP--DCLACQGGSQRPCSGNG-HCSGDGSRQGDGSC--RCHM 170
Query: 111 GFYG---------------DQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVH 155
G+ G ++ C +C +C+TC+G + +C C+ G L G CV
Sbjct: 171 GYQGPLCTDCMDGYFSSLRNETHSICTACDESCKTCSGLTNRDCGECEVGWVLDEGACVD 230
Query: 156 ATKTQEEGKFWNDILRKLQPCHSS--CKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTW 213
+ E PC ++ CK NGS T
Sbjct: 231 VDECAAEP----------PPCSAAQFCKNANGSYT------------------------- 255
Query: 214 PSVRSGSCENCTEACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGIC--- 270
CE C +C C+G G C +C G E G C
Sbjct: 256 -------CEECDSSCVGCTGEG----------------PGNC-KECISGYAREHGQCADV 291
Query: 271 ERCSSPCRTCEGNATNCHSCEGGHVLHHGVCQENCPERHVAVEGVC 316
+ CS +TC NC++ G +V CP+ E C
Sbjct: 292 DECSLAEKTCVRKNENCYNTPGSYVC-------VCPDGFEETEDAC 330
Score = 47.0 bits (110), Expect = 8e-05
Identities = 42/191 (21%), Positives = 64/191 (33%), Gaps = 48/191 (25%)
Query: 251 HEGRCYSKCPEGSYAE-----DGICERCSSPCRTCEGNAT-NCHSCEGGHVLHHGVCQEN 304
++G + C +G ++ IC C C+TC G +C CE G VL G C +
Sbjct: 172 YQGPLCTDCMDGYFSSLRNETHSICTACDESCKTCSGLTNRDCGECEVGWVLDEGACVD- 230
Query: 305 CPERHVAVEGVCKHCPEMCQDCIHEKTCKECMPEFFLHDDMCHQSCPRGFYADSHHCVPC 364
C C + CK S+ C C
Sbjct: 231 -----------VDECAAEPPPCSAAQFCKNAN--------------------GSYTCEEC 259
Query: 365 HKDCLECSGPKADDCELCLESSWVLYDGLC--LEECPAGTYYEKQTKECRDCHKSCLTCS 422
C+ C+G +C+ C+ S + G C ++EC K C +++C
Sbjct: 260 DSSCVGCTGEGPGNCKECI-SGYAREHGQCADVDECSLA------EKTCVRKNENCYNTP 312
Query: 423 SSGTCTTCQKG 433
S C C G
Sbjct: 313 GSYVC-VCPDG 322
Score = 46.2 bits (108), Expect = 1e-04
Identities = 56/223 (25%), Positives = 74/223 (33%), Gaps = 55/223 (24%)
Query: 513 CHSSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNSTGRCERCNRSC--KGCQ 570
C SS C Q W QL E Y D C + + C G
Sbjct: 83 CESSDFECNQMLEAQEEHLEAWWLQLKSE---------YPDLFEWFCVKTLKVCCSPGTY 133
Query: 571 GPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALNCL- 629
GP DCL+C +G R C + + C G G+
Sbjct: 134 GP---DCLAC---------QGGSQRPCSGNGH-----------------CSGDGSRQGDG 164
Query: 630 SCVWSYHLMGGICTSDCLVGEYRVGEGEKFN-CEKCHESCMECKGPGAKNCTLCPANLVL 688
SC G +CT DC+ G + E + C C ESC C G ++C C VL
Sbjct: 165 SCRCHMGYQGPLCT-DCMDGYFSSLRNETHSICTACDESCKTCSGLTNRDCGECEVGWVL 223
Query: 689 HMDESHCL---HCCNTSDPPSAQECC-------DCQDTTDECI 721
DE C+ C P SA + C C++ C+
Sbjct: 224 --DEGACVDVDECAAEPPPCSAAQFCKNANGSYTCEECDSSCV 264
>gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo
sapiens]
Length = 870
Score = 73.6 bits (179), Expect = 7e-13
Identities = 92/393 (23%), Positives = 125/393 (31%), Gaps = 75/393 (19%)
Query: 229 AICSGADLCKKCQM--QPGHPLFLHE---GRCYSKCPEGSYAEDGIC-ERCS----SPCR 278
A+C G C + ++ +PG H C +KCP + D C E CS C
Sbjct: 78 AVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPD--CKELCSCHPHGQCE 135
Query: 279 TCEGNATNCHS------CEGGHVLHHGVCQENCPERHVAVEGVCKHCP----EMCQDCIH 328
G T CH+ CE HG C G C+ P C +
Sbjct: 136 DVTGQCT-CHARRWGARCEHACQCQHGTCHPR--------SGACRCEPGWWGAQCASACY 186
Query: 329 EKTCKECMPEF---FLHDDMCHQSCPRGFYADSHHCVPCHKDCLECS------GPKADDC 379
C P+ H +SC +S PC + C G + D
Sbjct: 187 CSATSRCDPQTGACLCHAGWWGRSCNNQCACNSS---PCEQQSGRCQCRERTFGARCDRY 243
Query: 380 ELCLESSWVLYDGLCL-----------EECPAGTYYEKQTKECRDCHKSCLTCSSSGTCT 428
C DG C E CPAG Y + C C + G C
Sbjct: 244 CQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCL 303
Query: 429 TCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLL 488
TC+ G ++ C+ Y + + C PC + H +C C N+
Sbjct: 304 TCEPGW-----NGTKCDQPCATGFYGEGCSHRCPPC--RDGHACNHVTGKCTRC--NAGW 354
Query: 489 LNTTCVKDCPEGYYADEDSNRCAHCHSS--------CRTCEGRHSRQCH-SCRPGWFQLG 539
+ C C G Y ++ + CA C S C G H C+ +C PG G
Sbjct: 355 IGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLH--G 412
Query: 540 KECLLQCR-EGYYADNSTGRCERCNRSCKGCQG 571
+C C D TG C KG G
Sbjct: 413 ADCAQACSCHEDTCDPVTGACHLETNQRKGVMG 445
Score = 49.7 bits (117), Expect = 1e-05
Identities = 57/242 (23%), Positives = 72/242 (29%), Gaps = 87/242 (35%)
Query: 59 HCYKTCPEKTYSEAVECKACDSNCSSCD--------QNGCYWCEEGFFLLGGSCVRKCGP 110
+C + CP Y C C C + C CE G+ G C + C
Sbjct: 268 YCREPCPAGFYG-----LGCRRRCGQCKGQQPCTVAEGRCLTCEPGWN--GTKCDQPCAT 320
Query: 111 GFYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDIL 170
GFYG E C C C GH C H T
Sbjct: 321 GFYG-------EGCSHRCPPCR-DGH---------------ACNHVT------------- 344
Query: 171 RKLQPCHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAI 230
C CN A + C + C GT+ E+C CA
Sbjct: 345 -------GKCTRCN------------AGWIGDRCETKCSNGTYG-------EDCAFVCAD 378
Query: 231 CSGADLCK----KCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATN 286
C G+ C +C PG +H C CP G + D + CS TC+
Sbjct: 379 C-GSGHCDFQSGRCLCSPG----VHGPHCNVTCPPGLHGAD-CAQACSCHEDTCDPVTGA 432
Query: 287 CH 288
CH
Sbjct: 433 CH 434
Score = 37.0 bits (84), Expect = 0.078
Identities = 27/81 (33%), Positives = 30/81 (37%), Gaps = 5/81 (6%)
Query: 60 CYKTCPEKTYSEAVECKACDSNCSSCD-QNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEM 118
C C TY E D CD Q+G C G G C C PG +G
Sbjct: 359 CETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVH--GPHCNVTCPPGLHGADCA 416
Query: 119 GECESCHR-ACETCTGPGHDE 138
C SCH C+ TG H E
Sbjct: 417 QAC-SCHEDTCDPVTGACHLE 436
Score = 34.7 bits (78), Expect = 0.39
Identities = 48/197 (24%), Positives = 64/197 (32%), Gaps = 27/197 (13%)
Query: 527 QCHSCRPGWFQLGKECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFL 586
Q +C GW Q G EC + EG NST C N C RP +C C +F
Sbjct: 60 QVPTCCAGWRQQGDECGIAVCEG----NST--CSE-NEVC-----VRPGEC-RCRHGYF- 105
Query: 587 LRSKGECHRSCPDHYYVEQSTQTCERCHP--TCDQCKGKGALNC----LSCVWSYHLMGG 640
C CP ++ + C CHP C+ G+ + C + G
Sbjct: 106 ---GANCDTKCPRQFWGPDCKELCS-CHPHGQCEDVTGQCTCHARRWGARCEHACQCQHG 161
Query: 641 ICTSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGAKNCTLCPANLVLHMDESHCLHCCN 700
C G C+ S P C LC A + C CN
Sbjct: 162 TCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGAC-LCHAGWWGRSCNNQC--ACN 218
Query: 701 TSDPPSAQECCDCQDTT 717
+S C C++ T
Sbjct: 219 SSPCEQQSGRCQCRERT 235
>gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo
sapiens]
Length = 865
Score = 73.6 bits (179), Expect = 7e-13
Identities = 92/393 (23%), Positives = 125/393 (31%), Gaps = 75/393 (19%)
Query: 229 AICSGADLCKKCQM--QPGHPLFLHE---GRCYSKCPEGSYAEDGIC-ERCS----SPCR 278
A+C G C + ++ +PG H C +KCP + D C E CS C
Sbjct: 78 AVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPD--CKELCSCHPHGQCE 135
Query: 279 TCEGNATNCHS------CEGGHVLHHGVCQENCPERHVAVEGVCKHCP----EMCQDCIH 328
G T CH+ CE HG C G C+ P C +
Sbjct: 136 DVTGQCT-CHARRWGARCEHACQCQHGTCHPR--------SGACRCEPGWWGAQCASACY 186
Query: 329 EKTCKECMPEF---FLHDDMCHQSCPRGFYADSHHCVPCHKDCLECS------GPKADDC 379
C P+ H +SC +S PC + C G + D
Sbjct: 187 CSATSRCDPQTGACLCHAGWWGRSCNNQCACNSS---PCEQQSGRCQCRERTFGARCDRY 243
Query: 380 ELCLESSWVLYDGLCL-----------EECPAGTYYEKQTKECRDCHKSCLTCSSSGTCT 428
C DG C E CPAG Y + C C + G C
Sbjct: 244 CQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCL 303
Query: 429 TCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLL 488
TC+ G ++ C+ Y + + C PC + H +C C N+
Sbjct: 304 TCEPGW-----NGTKCDQPCATGFYGEGCSHRCPPC--RDGHACNHVTGKCTRC--NAGW 354
Query: 489 LNTTCVKDCPEGYYADEDSNRCAHCHSS--------CRTCEGRHSRQCH-SCRPGWFQLG 539
+ C C G Y ++ + CA C S C G H C+ +C PG G
Sbjct: 355 IGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLH--G 412
Query: 540 KECLLQCR-EGYYADNSTGRCERCNRSCKGCQG 571
+C C D TG C KG G
Sbjct: 413 ADCAQACSCHEDTCDPVTGACHLETNQRKGVMG 445
Score = 49.7 bits (117), Expect = 1e-05
Identities = 57/242 (23%), Positives = 72/242 (29%), Gaps = 87/242 (35%)
Query: 59 HCYKTCPEKTYSEAVECKACDSNCSSCD--------QNGCYWCEEGFFLLGGSCVRKCGP 110
+C + CP Y C C C + C CE G+ G C + C
Sbjct: 268 YCREPCPAGFYG-----LGCRRRCGQCKGQQPCTVAEGRCLTCEPGWN--GTKCDQPCAT 320
Query: 111 GFYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDIL 170
GFYG E C C C GH C H T
Sbjct: 321 GFYG-------EGCSHRCPPCR-DGH---------------ACNHVT------------- 344
Query: 171 RKLQPCHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAI 230
C CN A + C + C GT+ E+C CA
Sbjct: 345 -------GKCTRCN------------AGWIGDRCETKCSNGTYG-------EDCAFVCAD 378
Query: 231 CSGADLCK----KCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATN 286
C G+ C +C PG +H C CP G + D + CS TC+
Sbjct: 379 C-GSGHCDFQSGRCLCSPG----VHGPHCNVTCPPGLHGAD-CAQACSCHEDTCDPVTGA 432
Query: 287 CH 288
CH
Sbjct: 433 CH 434
Score = 37.0 bits (84), Expect = 0.078
Identities = 27/81 (33%), Positives = 30/81 (37%), Gaps = 5/81 (6%)
Query: 60 CYKTCPEKTYSEAVECKACDSNCSSCD-QNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEM 118
C C TY E D CD Q+G C G G C C PG +G
Sbjct: 359 CETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVH--GPHCNVTCPPGLHGADCA 416
Query: 119 GECESCHR-ACETCTGPGHDE 138
C SCH C+ TG H E
Sbjct: 417 QAC-SCHEDTCDPVTGACHLE 436
Score = 34.7 bits (78), Expect = 0.39
Identities = 48/197 (24%), Positives = 64/197 (32%), Gaps = 27/197 (13%)
Query: 527 QCHSCRPGWFQLGKECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFL 586
Q +C GW Q G EC + EG NST C N C RP +C C +F
Sbjct: 60 QVPTCCAGWRQQGDECGIAVCEG----NST--CSE-NEVC-----VRPGEC-RCRHGYF- 105
Query: 587 LRSKGECHRSCPDHYYVEQSTQTCERCHP--TCDQCKGKGALNC----LSCVWSYHLMGG 640
C CP ++ + C CHP C+ G+ + C + G
Sbjct: 106 ---GANCDTKCPRQFWGPDCKELCS-CHPHGQCEDVTGQCTCHARRWGARCEHACQCQHG 161
Query: 641 ICTSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGAKNCTLCPANLVLHMDESHCLHCCN 700
C G C+ S P C LC A + C CN
Sbjct: 162 TCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGAC-LCHAGWWGRSCNNQC--ACN 218
Query: 701 TSDPPSAQECCDCQDTT 717
+S C C++ T
Sbjct: 219 SSPCEQQSGRCQCRERT 235
>gi|145309306 scavenger receptor class F, member 1 isoform 5
precursor [Homo sapiens]
Length = 744
Score = 67.4 bits (163), Expect = 5e-11
Identities = 76/288 (26%), Positives = 103/288 (35%), Gaps = 57/288 (19%)
Query: 320 PEMCQD---CIHEKTCKECMPEFFLHDDMCHQSCPRGFYA-DSHHCVPCHKDCLECSGPK 375
P+ CQ C+ C+ C P FF C CP ++ D PCH +C P
Sbjct: 60 PDACQKDEVCVKPGLCR-CKPGFF--GAHCSSRCPGQYWGPDCRESCPCHPHG-QCE-PA 114
Query: 376 ADDCELCLESSWVLYDGLCLEECPAGTY--YEKQTKECR--------DCHKSCLTCSSSG 425
C+ C W C C G + + T C C + C +++
Sbjct: 115 TGACQ-CQADRW---GARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAA 170
Query: 426 TCTTCQKGLIMNP-----RGSCMANEKCSPSEYWDEDAPGCKP------CHVKCFHCMG- 473
C + P R S N SP E D C+P C +C G
Sbjct: 171 RCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQ-DSGRCACRPGWWGPECQQQCECVRGR 229
Query: 474 --PAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCH---------SSCRTCE- 521
A +C TCP C CP G + + ++ C C SC +CE
Sbjct: 230 CSAASGEC-TCPPG--FRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEP 286
Query: 522 GRHSRQCHS-CRPGWFQLGKECLLQC---REGYYADNSTGRCERCNRS 565
G + QC C PG F G+ C QC R G + TG C+RC+ S
Sbjct: 287 GWNGTQCQQPCLPGTF--GESCEQQCPHCRHGEACEPDTGHCQRCSGS 332
Score = 55.5 bits (132), Expect = 2e-07
Identities = 79/342 (23%), Positives = 106/342 (30%), Gaps = 78/342 (22%)
Query: 117 EMGECESCHRACETCTGPGHDECSSCQEGLQLLR-GMC--------VHATKTQEEGKFWN 167
E+ C + + CT P + +CQ+ ++ G+C H + ++ G++W
Sbjct: 38 ELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCS-SRCPGQYWG 96
Query: 168 DILRKLQPC--HSSCKTCNGSATL------------CTSCPKGAYLLAQACVSSCPQGTW 213
R+ PC H C+ G+ C P G A V C G W
Sbjct: 97 PDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRCDPATG-VCHCEPGWW 155
Query: 214 PSVRSGSCENCTEACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERC 273
S C+ C A A C A G C C G + RC
Sbjct: 156 SSTCRRPCQ-CNTAAARCEQA-----------------TGACV--CKPGWWG-----RRC 190
Query: 274 SSPCRTCEGNATNCHSCEGGHVLHHGVCQENCPERHVAVEGVCKHCPEMCQDCIHEKTCK 333
S C C G+ C G G C ++ V G C C
Sbjct: 191 SFRC-NCHGSP--CEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGEC---------- 237
Query: 334 ECMPEFFLHDDMCHQSCPRGFYADSHHCVPCHKDCLECS-----GPKADDCELCLESSWV 388
C P F C CP G H V C C C P CE C E W
Sbjct: 238 TCPPGF--RGARCELPCPAG-----SHGVQCAHSCGRCKHNEPCSPDTGSCESC-EPGW- 288
Query: 389 LYDGLCLEECPAGTYYEKQTKECRDCHKSCLTCSSSGTCTTC 430
C + C GT+ E ++C C +G C C
Sbjct: 289 -NGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRC 329
Score = 50.1 bits (118), Expect = 9e-06
Identities = 68/333 (20%), Positives = 103/333 (30%), Gaps = 71/333 (21%)
Query: 194 PKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKK---------CQMQP 244
PKG ++ CV+S P ++ IC G D C+K C+ +P
Sbjct: 24 PKGQHV----CVASSPSAELQCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKP 79
Query: 245 GHPLFLHEGRCYSKCPEGSYAED----------GICERCSSPCRTCEGN--ATNCH-SCE 291
G C S+CP + D G CE + C+ C+ + C C
Sbjct: 80 G----FFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQ-CQADRWGARCEFPCA 134
Query: 292 GGHVLHHGVCQENCPERHVAVEGVCKHCPEMCQDCIHEKTCKECMPEFFLHDDMCHQSCP 351
G HG C H C CQ C++ + C
Sbjct: 135 CGP---HGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCS 191
Query: 352 RGFYADSHHCVPCHKDCLECS------GPKADDCELCLESSWVLYDGLCL---------- 395
+ + H PC +D C+ GP+ C+ G C
Sbjct: 192 ---FRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCPPGFRGARC 248
Query: 396 -EECPAGTYYEKQTKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYW 454
CPAG++ + C C + +G+C +C+ G + C P +
Sbjct: 249 ELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGW-----NGTQCQQPCLPGTFG 303
Query: 455 DEDAPGCKPCHVKCFHC-----MGPAEDQCQTC 482
+ C +C HC P CQ C
Sbjct: 304 ES-------CEQQCPHCRHGEACEPDTGHCQRC 329
Score = 38.1 bits (87), Expect = 0.035
Identities = 29/89 (32%), Positives = 36/89 (40%), Gaps = 13/89 (14%)
Query: 60 CYKTCPEKTYSE--AVECKACDSN--CSSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGD 115
C CP ++ A C C N CS D C CE G+ G C + C PG +G+
Sbjct: 248 CELPCPAGSHGVQCAHSCGRCKHNEPCSP-DTGSCESCEPGWN--GTQCQQPCLPGTFGE 304
Query: 116 QEMGECESCH--RACETCTGPGHDECSSC 142
+C C ACE TG C C
Sbjct: 305 SCEQQCPHCRHGEACEPDTG----HCQRC 329
Score = 36.2 bits (82), Expect = 0.13
Identities = 45/171 (26%), Positives = 61/171 (35%), Gaps = 46/171 (26%)
Query: 78 CDSNCSSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGECESCHRACETCTGPGHD 137
C+ + S C+Q+ G C C PG++G + +CE C +G
Sbjct: 194 CNCHGSPCEQDS------------GRCA--CRPGWWGPECQQQCECVRGRCSAASG---- 235
Query: 138 ECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHS--SCK---TCNGSATLCTS 192
EC +C G + R C G +Q HS CK C+ C S
Sbjct: 236 EC-TCPPGFRGAR--CELPCPAGSHG---------VQCAHSCGRCKHNEPCSPDTGSCES 283
Query: 193 CPKGAYLLAQACVSSCPQGTW--------PSVRSG-SCENCTEACAICSGA 234
C G C C GT+ P R G +CE T C CSG+
Sbjct: 284 CEPG--WNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCSGS 332
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 67.4 bits (163), Expect = 5e-11
Identities = 102/440 (23%), Positives = 159/440 (36%), Gaps = 117/440 (26%)
Query: 214 PSVRSGSCENCTEACAICSGADLCKKCQ--MQPGHPLFLHE--GRCYSKCPEGSYAEDGI 269
P+V +C C G CK C+ +Q F + G+C+ C +G YA
Sbjct: 796 PNVVGRTCNRCAPG-TFGFGPSGCKPCECHLQGSVNAFCNPVTGQCH--CFQGVYARQ-- 850
Query: 270 CERC---------SSPCRTCEGNATNCHSCEGGHVLHHGVCQE-----NCPERHVAVEGV 315
C+RC PC+ C G+A +C G + CQ+ NC G
Sbjct: 851 CDRCLPGHWGFPSCQPCQ-CNGHADDCDPVTGECLN----CQDYTMGHNCERCLAGYYGD 905
Query: 316 --------CKHCP---------EMCQDCIHEKTCKE----CMPEFFLHDDMCHQSCPRGF 354
C+ CP + + C + + C P + C C G+
Sbjct: 906 PIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYI--GSRC-DDCASGY 962
Query: 355 YADSHH----CVPCH-KDCLECSGPKADDCEL--CLESSWVLYDGLCLEECPAGTYYEKQ 407
+ + C PC + ++ + P+A D E CL+ + C + C G Y +
Sbjct: 963 FGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHC-QFCRFGYYGDAL 1021
Query: 408 TKECRDC---HKSCLTCSSSGTCTTCQKGLIMNPRGSCMAN------EKCSPSEYWDEDA 458
++CR C + + +G+ C K + C+ N ++C+P+ +
Sbjct: 1022 QQDCRKCVCNYLGTVQEHCNGSDCQCDKA---TGQCLCLPNVIGQNCDRCAPNTWQLASG 1078
Query: 459 PGCKPCHVKCFHCMGPA----EDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCH 514
GC PC+ H GP+ QCQ P TC +C E ++ D D
Sbjct: 1079 TGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFG---GRTC-SECQELFWGDPD-------- 1126
Query: 515 SSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNSTGRC--------ERCNRSC 566
CR C+ C P + QC D STG+C RC++
Sbjct: 1127 VECRACD---------CDPRGIETP-----QC------DQSTGQCVCVEGVEGPRCDKCT 1166
Query: 567 KGCQGPRPTDCLSCDRFFFL 586
+G G P DC C + F L
Sbjct: 1167 RGYSGVFP-DCTPCHQCFAL 1185
Score = 49.7 bits (117), Expect = 1e-05
Identities = 101/451 (22%), Positives = 149/451 (33%), Gaps = 126/451 (27%)
Query: 43 PVQKQIHLKCGNRFDHHCYKTCPEKTYSEAVECKACDSNCSSCDQ--NGCYWCEEGFFLL 100
PV Q H G + C + P + + C+ + CD C C++ + +
Sbjct: 835 PVTGQCHCFQGV-YARQCDRCLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQD--YTM 891
Query: 101 GGSCVRKCGPGFYGDQEMGECESCHRACETCTGP--GHDECSSCQEGLQLLRGMCVHATK 158
G +C R C G+YGD +G + C R C GP G SC + L+ CV
Sbjct: 892 GHNCER-CLAGYYGDPIIGSGDHC-RPCPCPDGPDSGRQFARSCYQDPVTLQLACV---- 945
Query: 159 TQEEGKFWNDILRKLQPCHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRS 218
P + + C C G + G PS
Sbjct: 946 --------------CDPGYIGSR--------CDDCASGYF------------GN-PSEVG 970
Query: 219 GSCENC----------TEACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDG 268
GSC+ C EAC +G C KC L+ EG C G Y
Sbjct: 971 GSCQPCQCHNNIDTTDPEACDKETGR--CLKC-------LYHTEGEHCQFCRFGYYG--- 1018
Query: 269 ICERCSSPCRTCEGNATNCHSCEGGHVLHHGVCQENCPERHVAVEGVCKHCPEMCQDCIH 328
+ CR C N + G QE+C + C +C +
Sbjct: 1019 --DALQQDCRKCVCN-------------YLGTVQEHCNGSDCQCDKATGQC--LCLPNVI 1061
Query: 329 EKTCKECMPEFFLHDDMCHQSCPRGFYADSHHCVPCHKDCLECSGPKADD----CELCLE 384
+ C C P + A C PC+ + GP ++ C+ C+
Sbjct: 1062 GQNCDRCAPNTWQ-------------LASGTGCDPCNCNAAHSFGPSCNEFTGQCQ-CMP 1107
Query: 385 SSWVLYDGLCLEECPAGTYYEKQTKECRDCH------KSCLTCSSSGTCTTCQKGLIMNP 438
+ G EC ++ ECR C ++ S+G C C +G + P
Sbjct: 1108 G----FGGRTCSECQE-LFWGDPDVECRACDCDPRGIETPQCDQSTGQC-VCVEG-VEGP 1160
Query: 439 RGSCMANEKCSPSEYWDEDAPGCKPCHVKCF 469
R C +KC+ + P C PCH +CF
Sbjct: 1161 R--C---DKCTRG--YSGVFPDCTPCH-QCF 1183
Score = 43.9 bits (102), Expect = 6e-04
Identities = 71/323 (21%), Positives = 108/323 (33%), Gaps = 92/323 (28%)
Query: 474 PAEDQCQTC--PMNSLLLNTTCVKDC-PEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHS 530
P D C+ +++LL T +C P+G S+ C C+ R C+
Sbjct: 750 PMTDVCRNIIFSISALLHQTGLACECDPQGSL----SSVCDPNGGQCQCRPNVVGRTCNR 805
Query: 531 CRPGWFQLGK------ECLLQCREGYYADNSTGRC--------ERCNR---------SCK 567
C PG F G EC LQ + + TG+C +C+R SC+
Sbjct: 806 CAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQ 865
Query: 568 GCQ--------GPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHP-TCD 618
CQ P +CL+C + + G C YY + + + C P C
Sbjct: 866 PCQCNGHADDCDPVTGECLNCQDY-----TMGHNCERCLAGYYGDPIIGSGDHCRPCPCP 920
Query: 619 QCKGKG---ALNC--------LSCVWSYHLMGGICTSDCLVGEYRVGEGEKFNCE--KCH 665
G A +C L+CV +G C DC G + +C+ +CH
Sbjct: 921 DGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRC-DDCASGYFGNPSEVGGSCQPCQCH 979
Query: 666 ES---------------CMEC-KGPGAKNCTLCPANLVLHMDESHCLHC----------- 698
+ C++C ++C C + C C
Sbjct: 980 NNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKCVCNYLGTVQEH 1039
Query: 699 CNTSDPPSAQECCDCQDTTDECI 721
CN SD C C T +C+
Sbjct: 1040 CNGSD-------CQCDKATGQCL 1055
Score = 41.6 bits (96), Expect = 0.003
Identities = 70/318 (22%), Positives = 104/318 (32%), Gaps = 78/318 (24%)
Query: 252 EGRCYSKCPEGSYAEDGICERCSS-----PCRTCEGNATNCHSCEGGHVLHHGVCQENCP 306
EG + C + CE C P R EG N ++C+ + H +
Sbjct: 291 EGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGR--NSNACKKCNCNEHSISCHFDM 348
Query: 307 ERHVAVEGVCKHCPEMCQDCIHE---KTCKECMPEFFLHDDMCHQSCPRGFYADSHHCVP 363
++A V +C DC H + C++C P ++ H P D + C
Sbjct: 349 AVYLATGNVSGG---VCDDCQHNTMGRNCEQCKPFYYQH--------PERDIRDPNFCER 397
Query: 364 CHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKQTKECRDCHKSCLTCSS 423
C C C+ + S L G C C + + C C + SS
Sbjct: 398 C--TCDPAGSQNEGICDSYTDFSTGLIAGQC--RCKLNV----EGEHCDVCKEGFYDLSS 449
Query: 424 SGT--CTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQT 481
C +C NP G+ PG PC + HC
Sbjct: 450 EDPFGCKSC----ACNPLGT----------------IPGGNPCDSETGHCY--------- 480
Query: 482 CPMNSLLLNTTCVKDCPEGYYADEDSNRCAHC--------HSSCRTCEGRHSRQCHSCRP 533
L+ C + PE + D + C C ++SC S QC SCRP
Sbjct: 481 --CKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFA----ESGQC-SCRP 533
Query: 534 GWFQLGKECLLQCREGYY 551
+G++C + GYY
Sbjct: 534 --HMIGRQC-NEVEPGYY 548
Score = 37.0 bits (84), Expect = 0.078
Identities = 56/251 (22%), Positives = 81/251 (32%), Gaps = 61/251 (24%)
Query: 439 RGSCMAN---EKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTTCVK 495
RG+C +C+P + ++E+ G H C H C+ C
Sbjct: 268 RGNCFCYGHASECAPVDGFNEEVEGMVHGHCMCRH--NTKGLNCELC--------MDFYH 317
Query: 496 DCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNS 555
D P +SN C C+ + HS CH + G + S
Sbjct: 318 DLPWRPAEGRNSNACKKCNCN------EHSISCHFDMAVYLATG-------------NVS 358
Query: 556 TGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHP 615
G C+ C + G +C C F++ R D + CERC
Sbjct: 359 GGVCDDCQHNTMG------RNCEQCKPFYY-----QHPERDIRDPNF-------CERC-- 398
Query: 616 TCDQCKGKGALNCLSCV-WSYHLMGGICTSDCLVGEYRVGEGEKFNCEKCHESCMECKGP 674
TCD + C S +S L+ G C V EGE +C+ C E +
Sbjct: 399 TCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNV------EGE--HCDVCKEGFYDLSSE 450
Query: 675 GAKNCTLCPAN 685
C C N
Sbjct: 451 DPFGCKSCACN 461
Score = 34.3 bits (77), Expect = 0.50
Identities = 63/307 (20%), Positives = 94/307 (30%), Gaps = 90/307 (29%)
Query: 365 HKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKQTKECRDCHKSCLTCS-- 422
H C+ K +CELC++ Y L PA K+C +C++ ++C
Sbjct: 295 HGHCMCRHNTKGLNCELCMD----FYHDLPWR--PAEGRNSNACKKC-NCNEHSISCHFD 347
Query: 423 ----------SSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCM 472
S G C CQ + +C E+C P Y + P
Sbjct: 348 MAVYLATGNVSGGVCDDCQHNTMGR---NC---EQCKPFYYQHPERDIRDP--------- 392
Query: 473 GPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCR 532
+ C+ C + + D Y D + A CR C C+
Sbjct: 393 ----NFCERCTCDPAGSQNEGICDS----YTDFSTGLIA---GQCRCKLNVEGEHCDVCK 441
Query: 533 PGWFQLGKECLLQCRE-----------GYYADNSTGRCERCNRSCKGCQGPRPTDCLSCD 581
G++ L E C+ G D+ TG C C R G
Sbjct: 442 EGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHC-YCKRLVTG------------- 487
Query: 582 RFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALN--CLS----CVWSY 635
C + P+H+ + C C C GALN C + C
Sbjct: 488 ---------QHCDQCLPEHWGLSNDLDGCRPC-----DCDLGGALNNSCFAESGQCSCRP 533
Query: 636 HLMGGIC 642
H++G C
Sbjct: 534 HMIGRQC 540
>gi|84490388 R-spondin1 [Homo sapiens]
Length = 263
Score = 65.9 bits (159), Expect = 2e-10
Identities = 41/119 (34%), Positives = 55/119 (46%), Gaps = 18/119 (15%)
Query: 174 QPCHSSCKTCNGSATLCTSCPKGAYLLAQ--------ACVSSCPQGTWPSVRS--GSCEN 223
Q C C+ C+ C C ++L + C+ SCP G + + C
Sbjct: 38 QACAKGCELCS-EVNGCLKCSPKLFILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIK 96
Query: 224 CT-EACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCE 281
C E C C + C KC+ L+LH+GRCY CPEGS A +G E CSSP + CE
Sbjct: 97 CKIEHCEACFSHNFCTKCK----EGLYLHKGRCYPACPEGSSAANGTME-CSSPAQ-CE 149
Score = 54.3 bits (129), Expect = 5e-07
Identities = 31/93 (33%), Positives = 44/93 (47%), Gaps = 14/93 (15%)
Query: 76 KACDSNCSSCDQ-NGCYWCEEGFFLL--------GGSCVRKCGPGFYG--DQEMGECESC 124
+AC C C + NGC C F+L G C+ C PG++ + +M +C C
Sbjct: 38 QACAKGCELCSEVNGCLKCSPKLFILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKC 97
Query: 125 H-RACETCTGPGHDECSSCQEGLQLLRGMCVHA 156
CE C H+ C+ C+EGL L +G C A
Sbjct: 98 KIEHCEACFS--HNFCTKCKEGLYLHKGRCYPA 128
Score = 48.5 bits (114), Expect = 3e-05
Identities = 33/130 (25%), Positives = 46/130 (35%), Gaps = 24/130 (18%)
Query: 271 ERCSSPCRTCEGNATNCHSC--------EGGHVLHHGVCQENCPERHVAVEGV----CKH 318
+ C+ C C C C E + GVC +CP + C
Sbjct: 38 QACAKGCELCS-EVNGCLKCSPKLFILLERNDIRQVGVCLPSCPPGYFDARNPDMNKCIK 96
Query: 319 CP-EMCQDCIHEKTCKECMPEFFLHDDMCHQSCPRGFYADSHHCVPCHKDCLECSGPKAD 377
C E C+ C C +C +LH C+ +CP G A + +ECS P
Sbjct: 97 CKIEHCEACFSHNFCTKCKEGLYLHKGRCYPACPEGSSAAN--------GTMECSSPA-- 146
Query: 378 DCELCLESSW 387
CE+ S W
Sbjct: 147 QCEMSEWSPW 156
Score = 46.6 bits (109), Expect = 1e-04
Identities = 43/152 (28%), Positives = 64/152 (42%), Gaps = 40/152 (26%)
Query: 348 QSCPRGFYADSHHCVPCHK--DCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYE 405
Q+C +G C C + CL+CS PK + LE + + G+CL CP G Y++
Sbjct: 38 QACAKG-------CELCSEVNGCLKCS-PKLF---ILLERNDIRQVGVCLPSCPPG-YFD 85
Query: 406 KQTKECRDCHKS----CLTCSSSGTCTTCQKGLIMN--------PRGSCMAN---EKCSP 450
+ + C K C C S CT C++GL ++ P GS AN E SP
Sbjct: 86 ARNPDMNKCIKCKIEHCEACFSHNFCTKCKEGLYLHKGRCYPACPEGSSAANGTMECSSP 145
Query: 451 SEYWDEDAPGCKPCHVKCFHCMGPAEDQCQTC 482
++ C + + GP + Q C
Sbjct: 146 AQ-----------CEMSEWSPWGPCSKKQQLC 166
Score = 43.1 bits (100), Expect = 0.001
Identities = 38/145 (26%), Positives = 51/145 (35%), Gaps = 23/145 (15%)
Query: 419 LTCSSSGTCTTCQKGLIMNPRGSCMAN-EKCSPSEYWDEDAPGCKPCHVKCFHCMGPAED 477
LT SS G Q+ + +C E CS + GC C K F +
Sbjct: 17 LTISSRGIKGKRQRRISAEGSQACAKGCELCS-------EVNGCLKCSPKLFILL----- 64
Query: 478 QCQTCPMNSLLLNTTCVKDCPEGYY--ADEDSNRCAHCH-SSCRTCEGRHSRQCHSCRPG 534
N + C+ CP GY+ + D N+C C C C + C C+ G
Sbjct: 65 -----ERNDIRQVGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHNF--CTKCKEG 117
Query: 535 WFQLGKECLLQCREGYYADNSTGRC 559
+ C C EG A N T C
Sbjct: 118 LYLHKGRCYPACPEGSSAANGTMEC 142
Score = 35.8 bits (81), Expect = 0.17
Identities = 32/135 (23%), Positives = 48/135 (35%), Gaps = 20/135 (14%)
Query: 487 LLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGKE----- 541
L +++ +K + + E S CA C G C C P F L +
Sbjct: 17 LTISSRGIKGKRQRRISAEGSQACAKGCELCSEVNG-----CLKCSPKLFILLERNDIRQ 71
Query: 542 ---CLLQCREGYY--ADNSTGRCERCN-RSCKGCQGPRPTDCLSCDRFFFLLRSKGECHR 595
CL C GY+ + +C +C C+ C C C +L KG C+
Sbjct: 72 VGVCLPSCPPGYFDARNPDMNKCIKCKIEHCEACFSHN--FCTKCKEGLYL--HKGRCYP 127
Query: 596 SCPDHYYVEQSTQTC 610
+CP+ T C
Sbjct: 128 ACPEGSSAANGTMEC 142
Score = 35.8 bits (81), Expect = 0.17
Identities = 27/100 (27%), Positives = 38/100 (38%), Gaps = 11/100 (11%)
Query: 60 CYKTCPEKTY-------SEAVECKACDSNCSSC-DQNGCYWCEEGFFLLGGSCVRKCGPG 111
C +CP + ++ ++CK +C +C N C C+EG +L G C C G
Sbjct: 75 CLPSCPPGYFDARNPDMNKCIKCKI--EHCEACFSHNFCTKCKEGLYLHKGRCYPACPEG 132
Query: 112 FYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRG 151
EC S CE CS Q+ RG
Sbjct: 133 SSAANGTMECSS-PAQCEMSEWSPWGPCSKKQQLCGFRRG 171
>gi|51873053 fibulin 2 isoform a precursor [Homo sapiens]
Length = 1231
Score = 65.9 bits (159), Expect = 2e-10
Identities = 111/485 (22%), Positives = 166/485 (34%), Gaps = 135/485 (27%)
Query: 273 CSSPCRTCEGNATNCHSCEGGHVLHHGVCQENCPERHVAVEGVCKHCPEMCQDCIHEKTC 332
C C T G+A C G ++ GV E+ E C DC + C
Sbjct: 689 CKQVCSTVGGSAI-CSCFPGYAIMADGVSCEDQDE-----------CLMGAHDCSRRQFC 736
Query: 333 KECMPEFFLHDDMCHQSCPRGFYADSHH-CVP---CHKDCLECSGPKADDC--------- 379
+ F+ + C G+ ++H CV C D CS + + C
Sbjct: 737 VNTLGSFYCVNHTV--LCADGYILNAHRKCVDINECVTDLHTCS--RGEHCVNTLGSFHC 792
Query: 380 --ELCLESSWVLYDGLC--LEECPAGTYYEKQTKECRDCHKSCLTCSSSGTCTTCQKGLI 435
L E + L DG C ++EC GT+ + C++ K C + C G +
Sbjct: 793 YKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNT-KGSFYCQAR---QRCMDGFL 848
Query: 436 MNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTTCVK 495
+P G+C+ +C+ + C+P C + +G TC N L+
Sbjct: 849 QDPEGNCVDINECTSL------SEPCRP-GFSCINTVG-----SYTCQRNPLI------- 889
Query: 496 DCPEGYYADEDSNRCA---HCHSSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCREGYYA 552
C GY+A +D +C C + C + CH+ PG ++ C+ G+
Sbjct: 890 -CARGYHASDDGTKCVDVNECETGVHRC--GEGQVCHNL-PGSYR------CDCKAGFQR 939
Query: 553 DNSTGRC-----------ERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGE--------- 592
D C C +C+ G C S FLL + G+
Sbjct: 940 DAFGRGCIDVNECWASPGRLCQHTCENTLGSYRCSCAS----GFLLAADGKRCEDVNECE 995
Query: 593 ---CHRSCPDHY-----YVEQSTQTCERCHPTC---DQC-KGKGAL---NCLSCVWSYHL 637
C + C + Y Y Q Q E H TC D+C +G G L CL+ SY
Sbjct: 996 AQRCSQECANIYGSYQCYCRQGYQLAEDGH-TCTDIDECAQGAGILCTFRCLNVPGSYQC 1054
Query: 638 M-----------GGIC--TSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGAKNCTL--C 682
G C +C +G + E E CH G+ C C
Sbjct: 1055 ACPEQGYTMTANGRSCKDVDECALGTHNCSE-----AETCHNI------QGSFRCLRFEC 1103
Query: 683 PANLV 687
P N V
Sbjct: 1104 PPNYV 1108
Score = 58.9 bits (141), Expect = 2e-08
Identities = 119/516 (23%), Positives = 182/516 (35%), Gaps = 104/516 (20%)
Query: 83 SSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGECESCHRACETCTGPGHDECSSC 142
++C NG C++ +GGS + C PG+ M + SC E G HD CS
Sbjct: 681 NTCKDNGP--CKQVCSTVGGSAICSCFPGY---AIMADGVSCEDQDECLMG-AHD-CSRR 733
Query: 143 QEGLQLLRGM-CVHATKTQEEGKFWNDILRKLQPCHSSCKTCNGSATLCTSCPKGAYLLA 201
Q + L CV+ T +G N H C N T +C +G + +
Sbjct: 734 QFCVNTLGSFYCVNHTVLCADGYILN--------AHRKCVDINECVTDLHTCSRGEHCVN 785
Query: 202 QA----CVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKK---CQMQPGHPLFLHEGR 254
C + +++ G CE+ E CA+ G C+ CQ G R
Sbjct: 786 TLGSFHCYKALTCEPGYALKDGECEDVDE-CAM--GTHTCQPGFLCQNTKGSFYCQARQR 842
Query: 255 C---YSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEGGHVLHHGVCQEN---CPER 308
C + + PEG+ + C S PCR +C + G + CQ N C
Sbjct: 843 CMDGFLQDPEGNCVDINECTSLSEPCRP----GFSCINTVGSY-----TCQRNPLICARG 893
Query: 309 HVAVEGVCKHCPEM--CQDCIHEKTCKECMPEFFLHDDMCHQ-------SCPRGFYADS- 358
+ A + K C ++ C+ +H C E +CH C GF D+
Sbjct: 894 YHASDDGTK-CVDVNECETGVHR--CGE--------GQVCHNLPGSYRCDCKAGFQRDAF 942
Query: 359 -HHCVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKQTKECRD---- 413
C+ D EC C+ E++ Y C C +G K C D
Sbjct: 943 GRGCI----DVNECWASPGRLCQHTCENTLGSY--RC--SCASGFLLAADGKRCEDVNEC 994
Query: 414 ----CHKSCLTCSSSGTCTTCQKGLIMNPRG-SCMANEKCSPSEYWDEDAPGCKPCHVKC 468
C + C S C C++G + G +C ++C+ + + C
Sbjct: 995 EAQRCSQECANIYGSYQC-YCRQGYQLAEDGHTCTDIDECA------------QGAGILC 1041
Query: 469 -FHCMG-PAEDQCQTCPMN--SLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRH 524
F C+ P QC CP ++ N KD E + + CH+ +G
Sbjct: 1042 TFRCLNVPGSYQC-ACPEQGYTMTANGRSCKDVDECALGTHNCSEAETCHN----IQGSF 1096
Query: 525 SRQCHSCRPGWFQLGK-EC-LLQCREGYYADNSTGR 558
C P + Q+ K +C C + NS R
Sbjct: 1097 RCLRFECPPNYVQVSKTKCERTTCHDFLECQNSPAR 1132
Score = 38.5 bits (88), Expect = 0.027
Identities = 63/295 (21%), Positives = 95/295 (32%), Gaps = 64/295 (21%)
Query: 407 QTKECRD---CHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKP 463
Q C+D C + C T S C+ IM SC ++C + C
Sbjct: 679 QPNTCKDNGPCKQVCSTVGGSAICSCFPGYAIMADGVSCEDQDECLMGAHDCSRRQFCVN 738
Query: 464 CHVKCFHCMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGR 523
+ F+C+ + C + +LN + C + D + C+ T
Sbjct: 739 T-LGSFYCV----NHTVLC-ADGYILNAH--RKCVDINECVTDLHTCSRGEHCVNTLGSF 790
Query: 524 HSRQCHSCRPGWFQLGKEC---------LLQCREGYYADNSTGR--CERCNRSCKGCQGP 572
H + +C PG+ EC C+ G+ N+ G C+ R G
Sbjct: 791 HCYKALTCEPGYALKDGECEDVDECAMGTHTCQPGFLCQNTKGSFYCQARQRCMDG---- 846
Query: 573 RPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALNC---- 628
FL +G C + + T E C P G+ C
Sbjct: 847 ------------FLQDPEGNC-------VDINECTSLSEPCRPGFSCINTVGSYTCQRNP 887
Query: 629 LSCVWSYHLM--GGIC--TSDCLVGEYRVGEGEKFNCEKCHESCMECKGPGAKNC 679
L C YH G C ++C G +R GEG + CH PG+ C
Sbjct: 888 LICARGYHASDDGTKCVDVNECETGVHRCGEG-----QVCHNL------PGSYRC 931
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 65.1 bits (157), Expect = 3e-10
Identities = 122/513 (23%), Positives = 171/513 (33%), Gaps = 129/513 (25%)
Query: 192 SCPKGAYLLAQACVSSCPQG--------TWPSVR-------SGSCENC-----TEACAIC 231
S P + A V CP G WP R G CE C E+C
Sbjct: 710 SYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDV 769
Query: 232 SGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAE-----DGICERCSSPCRTCEGN-AT 285
+G C C+ G P KC G Y E C+ C+ P N +
Sbjct: 770 TGE--CLNCKDHTGGPYC-------DKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSP 820
Query: 286 NCHS-------CEGGHVLHHGVCQENCPERHVAVEGV----CKHCPEMCQDCIH------ 328
CH C+G V + G E C E + V C+ C C D +
Sbjct: 821 TCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPC--QCNDNLDFSIPGS 878
Query: 329 ----EKTCKECMPEFFLHDDMCHQSCPRGFYADS---HHCVPCHKDC----LECSGPKAD 377
+C C P C + C G++ D+ +C PC + E +
Sbjct: 879 CDSLSGSCLICKPG--TTGRYC-ELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTG 935
Query: 378 DCELCLESSWVLYDGLCLEECPAGTYYEKQTKECRDCH-----KSCLTCSSSGTCTTCQK 432
CE C + G ++C AGT+ + + C C+ C SG C CQ
Sbjct: 936 QCE-CRAN----VQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCW-CQP 989
Query: 433 GLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHC---MGPAEDQCQTCPMNSLLL 489
G+ C Y++ GC C +C H P +C CP N++
Sbjct: 990 GVTGKKCDRCAHG-------YFNFQEGGCTAC--ECSHLGNNCDPKTGRC-ICPPNTI-- 1037
Query: 490 NTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCH------SCRPGWFQLGKECL 543
C K C + + C C+ C T G QC+ +C P + G +C
Sbjct: 1038 GEKCSK-CAPNTWGHSITTGCKACN--CSTV-GSLDFQCNVNTGQCNCHPKFS--GAKCT 1091
Query: 544 LQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHY-- 601
+C G++ + RC C+ G TD +CD +C SC D
Sbjct: 1092 -ECSRGHW---NYPRCNLCDCFLPG------TDATTCDS------ETKKC--SCSDQTGQ 1133
Query: 602 ---YVEQSTQTCERCHPTCDQCKGKGALNCLSC 631
V C+RC P K L C SC
Sbjct: 1134 CTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSC 1166
Score = 63.5 bits (153), Expect = 8e-10
Identities = 118/528 (22%), Positives = 166/528 (31%), Gaps = 162/528 (30%)
Query: 78 CDSNCSSCDQ--NGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGECESCHRACETCTGPG 135
C + SCD C C++ GG KC PGFYG+ G E C P
Sbjct: 759 CFGHAESCDDVTGECLNCKDH---TGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPS 815
Query: 136 HDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSCKTCNGSATLCTSCPK 195
++ +C L +C CP
Sbjct: 816 NNFSPTCHLDRSL--------------------------------------GLICDGCPV 837
Query: 196 GAYLLAQACVSSCPQGTW--PSVRSGSCENC----------TEACAICSGADLCKKCQMQ 243
G C C +G + PSV GSC+ C +C SG+ C C +
Sbjct: 838 G--YTGPRC-ERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGS--CLIC--K 890
Query: 244 PGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATN--CHSCEGGHVLHHGVC 301
PG GR C +G Y D + + PCR G + + CHS G C
Sbjct: 891 PG-----TTGRYCELCADG-YFGDAVDAKNCQPCRCNAGGSFSEVCHS-------QTGQC 937
Query: 302 QENCPERHVAVEGVCKHCPEMCQDCIHEKTCKECMPEFFLHDDMCHQSCPRGFYADSHHC 361
+ C+ + + C +C F + C
Sbjct: 938 E--------------------CRANVQGQRCDKCKAGTF-------------GLQSARGC 964
Query: 362 VPCHKDCLECSGPKADDCELCLESS--WVLYDGLCLEECP--AGTYYEKQTKECRDCHKS 417
VPC+ + G K+ DCE ES W G+ ++C A Y+ Q C C
Sbjct: 965 VPCNCNSF---GSKSFDCE---ESGQCW-CQPGVTGKKCDRCAHGYFNFQEGGCTACE-- 1015
Query: 418 CLTCSSSGTCTTCQKGLIMNPRGSCMAN-EKCSPSEYWDEDAPGCKPCHVKCFHCMGPAE 476
CS G + G + P + KC+P+ + GCK C+ +G +
Sbjct: 1016 ---CSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCS---TVGSLD 1069
Query: 477 DQCQT----CPMNSLLLNTTCVKDCPEGYYADEDSNRC---------AHCHSSCRTC--- 520
QC C + C +C G++ N C C S + C
Sbjct: 1070 FQCNVNTGQCNCHPKFSGAKCT-ECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCS 1128
Query: 521 ------------EGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNST 556
EG H C CRPG F L + L C Y +T
Sbjct: 1129 DQTGQCTCKVNVEGIH---CDRCRPGKFGLDAKNPLGCSSCYCFGTTT 1173
Score = 48.9 bits (115), Expect = 2e-05
Identities = 54/232 (23%), Positives = 84/232 (36%), Gaps = 34/232 (14%)
Query: 75 CKACDSNCSSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMG----ECESCHRACET 130
C + S C+++G WC+ G + G C R C G++ QE G EC C+
Sbjct: 969 CNSFGSKSFDCEESGQCWCQPG--VTGKKCDR-CAHGYFNFQEGGCTACECSHLGNNCDP 1025
Query: 131 CTG----PGH---DECSSCQE---GLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSC 180
TG P + ++CS C G + G T F ++ CH
Sbjct: 1026 KTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKF 1085
Query: 181 KTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKKC 240
S CT C +G + + + C P + +C++ T+ C+ C C
Sbjct: 1086 -----SGAKCTECSRGHWNYPRCNLCDC---FLPGTDATTCDSETKKCSCSDQTGQC-TC 1136
Query: 241 QMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEG 292
++ EG +C G + D S C C G T C +G
Sbjct: 1137 KVNV-------EGIHCDRCRPGKFGLDAKNPLGCSSC-YCFGTTTQCSEAKG 1180
Score = 38.1 bits (87), Expect = 0.035
Identities = 52/253 (20%), Positives = 76/253 (30%), Gaps = 58/253 (22%)
Query: 348 QSCPRGFYADSHHCVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKQ 407
++CP + C H C D C+ C G + AGT+ K
Sbjct: 294 RACPLDPATNKSRCECEHNTC-------GDSCDQCCP-------GFHQKPWRAGTFLTKT 339
Query: 408 TKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVK 467
E +CH C ++ L +N RG + C + C+ C
Sbjct: 340 ECEACNCHGKAEECYYDEN--VARRNLSLNIRGKYIGGGVCINCTQ-NTAGINCETCTDG 396
Query: 468 CFHCMGPAEDQ---CQTCPMNSL-LLNTTCVKD--------------------------C 497
F G + + CQ C + + LN CVKD C
Sbjct: 397 FFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRC 456
Query: 498 PEGYYADEDSNRCA----------HCHSSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCR 547
GY D C C C E C C+ G+F L ++ C
Sbjct: 457 ARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCD 516
Query: 548 EGYYADNSTGRCE 560
E + + RC+
Sbjct: 517 E-CFCSGVSNRCQ 528
Score = 36.6 bits (83), Expect = 0.10
Identities = 44/179 (24%), Positives = 63/179 (35%), Gaps = 45/179 (25%)
Query: 128 CETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPC----HSS---- 179
C+ G C +C G LR +Q G+ L PC HSS
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLR--------SQPGGRTPGPTLGTCVPCQCNGHSSLCDP 1431
Query: 180 ----CKTC--NGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSG 233
C+ C + + C C G Y + + + C Q P + S + N + +C + G
Sbjct: 1432 ETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSN--NFSPSC-VAEG 1488
Query: 234 ADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGN-ATNCHSCE 291
D + RC + CP G E CERC+ GN +C CE
Sbjct: 1489 LD----------------DYRC-TACPRG--YEGQYCERCAPGYTGSPGNPGGSCQECE 1528
Score = 33.9 bits (76), Expect = 0.66
Identities = 60/251 (23%), Positives = 78/251 (31%), Gaps = 51/251 (20%)
Query: 69 YSEAVECK---ACDSNCSSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMG------ 119
Y A C A + + C+ N C G SC +C PGF+
Sbjct: 290 YGHARACPLDPATNKSRCECEHNTC----------GDSC-DQCCPGFHQKPWRAGTFLTK 338
Query: 120 -ECESC--HRACETC---TGPGHDECSSCQEGLQLLRGMCVHATK--------TQEEGKF 165
ECE+C H E C S G + G+C++ T+ T +G F
Sbjct: 339 TECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFF 398
Query: 166 WN-----DILRKLQPCHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGS 220
+ R QPCH C +C K A C G S
Sbjct: 399 RPKGVSPNYPRPCQPCH--CDPIGSLNEVCVKDEKHARRGLAPGSCHCKTG----FGGVS 452
Query: 221 CENCTEACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSP-CRT 279
C+ C +G CK C +E C+ C E G C RC S
Sbjct: 453 CDRCARGY---TGYPDCKACNCSGLGSK--NEDPCFGPCICKENVEGGDCSRCKSGFFNL 507
Query: 280 CEGNATNCHSC 290
E N C C
Sbjct: 508 QEDNWKGCDEC 518
Score = 33.9 bits (76), Expect = 0.66
Identities = 46/179 (25%), Positives = 63/179 (35%), Gaps = 52/179 (29%)
Query: 577 CLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALN------CLS 630
C +C F+ LRS+ P + TC C QC G +L C +
Sbjct: 1391 CEACLPGFYRLRSQPGGRTPGP-------TLGTCVPC-----QCNGHSSLCDPETSICQN 1438
Query: 631 CVWSYHLMGGICTSDCLVGEYRVGEGEKFNCEKC-----------HESCMECKGPGAKNC 679
C +H G C C +G Y + +G +C++C SC+ +G C
Sbjct: 1439 C--QHHTAGDFCER-CALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCV-AEGLDDYRC 1494
Query: 680 TLCPANLVLHMDESHCLHCC--NTSDP----PSAQEC-CD--------CQDTTDECILR 723
T CP + +C C T P S QEC CD C T C R
Sbjct: 1495 TACPRG----YEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCR 1549
Score = 32.0 bits (71), Expect = 2.5
Identities = 52/219 (23%), Positives = 74/219 (33%), Gaps = 72/219 (32%)
Query: 262 GSYAEDGICERCSSPCRTCEGNATNCHSCEG-----------GHVLHHGVCQ-------- 302
G++ CE C+ C G A C+ E G + GVC
Sbjct: 333 GTFLTKTECEACN-----CHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAG 387
Query: 303 ---ENCPERHVAVEGVCKHCPEMCQDCIHEKTCKECMPEFFLHDDMC---HQSCPRGFYA 356
E C + +GV + P CQ C C P L +++C + RG
Sbjct: 388 INCETCTDGFFRPKGVSPNYPRPCQPC-------HCDPIGSL-NEVCVKDEKHARRGLAP 439
Query: 357 DSHHC------VPC---------HKDCLECS----GPKADD-----CELCLESSWVLYDG 392
S HC V C + DC C+ G K +D C +C E+ +G
Sbjct: 440 GSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPC-ICKEN----VEG 494
Query: 393 LCLEECPAGTYYEKQTKECRDCHKSCLTCSSSGTCTTCQ 431
C +G + ++ D K C C SG CQ
Sbjct: 495 GDCSRCKSGFFNLQE-----DNWKGCDECFCSGVSNRCQ 528
Score = 30.8 bits (68), Expect = 5.6
Identities = 68/308 (22%), Positives = 105/308 (34%), Gaps = 58/308 (18%)
Query: 268 GICERCSSPCRTCEGN-ATNCHSCEGGHVLHHGVCQENCPERHVAVEGVCKHCPEM-CQD 325
G+C C R C + ATN CE H C + CP H + C+
Sbjct: 285 GMCI-CYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEA 343
Query: 326 CIHEKTCKECMPEFFLHDDMCHQSCP---RGFYADSHHCVPCHKDCLECSGPKADDCELC 382
C +EC + +++ ++ RG Y C+ C ++ +CE C
Sbjct: 344 CNCHGKAEEC----YYDENVARRNLSLNIRGKYIGGGVCINCTQN------TAGINCETC 393
Query: 383 LESSWVLYDGLCLEECPAGTYYEKQTKECRDCHKSCLTCSSSGTCTTCQK----GLIMNP 438
DG + + Y + C+ CH + S + C +K GL
Sbjct: 394 T-------DGFFRPKGVSPNY----PRPCQPCHCDPIG-SLNEVCVKDEKHARRGL---A 438
Query: 439 RGSC-----MANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQC-QTCPMNSLLLNTT 492
GSC C P CK C+ C ED C C +
Sbjct: 439 PGSCHCKTGFGGVSCDRCARGYTGYPDCKACN--CSGLGSKNEDPCFGPCICKENVEGGD 496
Query: 493 CVKDCPEGYYADEDSN--RCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCREGY 550
C + C G++ ++ N C C C G +R C+ ++ GK +Q G+
Sbjct: 497 CSR-CKSGFFNLQEDNWKGCDECF-----CSGVSNR----CQSSYWTYGK---IQDMSGW 543
Query: 551 YADNSTGR 558
Y + GR
Sbjct: 544 YLTDLPGR 551
Score = 30.4 bits (67), Expect = 7.3
Identities = 40/165 (24%), Positives = 52/165 (31%), Gaps = 47/165 (28%)
Query: 441 SCMANEKCSPSEYWDEDAPG----------CKPCHVKCFHCM-GPAEDQCQTCPMNSLLL 489
S ++ E C P Y PG C PC + P CQ C ++
Sbjct: 1387 SGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQHHTA-- 1444
Query: 490 NTTCVKDCPEGYYA-----DEDSNRCA--------HCHSSCRTCEGRHSRQCHSCRPGWF 536
C + C GYY D +CA + SC EG +C +C G+
Sbjct: 1445 GDFCER-CALGYYGIVKGLPNDCQQCACPLISSSNNFSPSC-VAEGLDDYRCTACPRGY- 1501
Query: 537 QLGKECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCD 581
EG Y CERC G G C C+
Sbjct: 1502 -----------EGQY-------CERCAPGYTGSPGNPGGSCQECE 1528
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 65.1 bits (157), Expect = 3e-10
Identities = 122/513 (23%), Positives = 171/513 (33%), Gaps = 129/513 (25%)
Query: 192 SCPKGAYLLAQACVSSCPQG--------TWPSVR-------SGSCENC-----TEACAIC 231
S P + A V CP G WP R G CE C E+C
Sbjct: 710 SYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDV 769
Query: 232 SGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAE-----DGICERCSSPCRTCEGN-AT 285
+G C C+ G P KC G Y E C+ C+ P N +
Sbjct: 770 TGE--CLNCKDHTGGPYC-------DKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSP 820
Query: 286 NCHS-------CEGGHVLHHGVCQENCPERHVAVEGV----CKHCPEMCQDCIH------ 328
CH C+G V + G E C E + V C+ C C D +
Sbjct: 821 TCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPC--QCNDNLDFSIPGS 878
Query: 329 ----EKTCKECMPEFFLHDDMCHQSCPRGFYADS---HHCVPCHKDC----LECSGPKAD 377
+C C P C + C G++ D+ +C PC + E +
Sbjct: 879 CDSLSGSCLICKPG--TTGRYC-ELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTG 935
Query: 378 DCELCLESSWVLYDGLCLEECPAGTYYEKQTKECRDCH-----KSCLTCSSSGTCTTCQK 432
CE C + G ++C AGT+ + + C C+ C SG C CQ
Sbjct: 936 QCE-CRAN----VQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCW-CQP 989
Query: 433 GLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHC---MGPAEDQCQTCPMNSLLL 489
G+ C Y++ GC C +C H P +C CP N++
Sbjct: 990 GVTGKKCDRCAHG-------YFNFQEGGCTAC--ECSHLGNNCDPKTGRC-ICPPNTI-- 1037
Query: 490 NTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSRQCH------SCRPGWFQLGKECL 543
C K C + + C C+ C T G QC+ +C P + G +C
Sbjct: 1038 GEKCSK-CAPNTWGHSITTGCKACN--CSTV-GSLDFQCNVNTGQCNCHPKFS--GAKCT 1091
Query: 544 LQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHY-- 601
+C G++ + RC C+ G TD +CD +C SC D
Sbjct: 1092 -ECSRGHW---NYPRCNLCDCFLPG------TDATTCDS------ETKKC--SCSDQTGQ 1133
Query: 602 ---YVEQSTQTCERCHPTCDQCKGKGALNCLSC 631
V C+RC P K L C SC
Sbjct: 1134 CTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSC 1166
Score = 63.5 bits (153), Expect = 8e-10
Identities = 118/528 (22%), Positives = 166/528 (31%), Gaps = 162/528 (30%)
Query: 78 CDSNCSSCDQ--NGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGECESCHRACETCTGPG 135
C + SCD C C++ GG KC PGFYG+ G E C P
Sbjct: 759 CFGHAESCDDVTGECLNCKDH---TGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPS 815
Query: 136 HDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSCKTCNGSATLCTSCPK 195
++ +C L +C CP
Sbjct: 816 NNFSPTCHLDRSL--------------------------------------GLICDGCPV 837
Query: 196 GAYLLAQACVSSCPQGTW--PSVRSGSCENC----------TEACAICSGADLCKKCQMQ 243
G C C +G + PSV GSC+ C +C SG+ C C +
Sbjct: 838 G--YTGPRC-ERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGS--CLIC--K 890
Query: 244 PGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATN--CHSCEGGHVLHHGVC 301
PG GR C +G Y D + + PCR G + + CHS G C
Sbjct: 891 PG-----TTGRYCELCADG-YFGDAVDAKNCQPCRCNAGGSFSEVCHS-------QTGQC 937
Query: 302 QENCPERHVAVEGVCKHCPEMCQDCIHEKTCKECMPEFFLHDDMCHQSCPRGFYADSHHC 361
+ C+ + + C +C F + C
Sbjct: 938 E--------------------CRANVQGQRCDKCKAGTF-------------GLQSARGC 964
Query: 362 VPCHKDCLECSGPKADDCELCLESS--WVLYDGLCLEECP--AGTYYEKQTKECRDCHKS 417
VPC+ + G K+ DCE ES W G+ ++C A Y+ Q C C
Sbjct: 965 VPCNCNSF---GSKSFDCE---ESGQCW-CQPGVTGKKCDRCAHGYFNFQEGGCTACE-- 1015
Query: 418 CLTCSSSGTCTTCQKGLIMNPRGSCMAN-EKCSPSEYWDEDAPGCKPCHVKCFHCMGPAE 476
CS G + G + P + KC+P+ + GCK C+ +G +
Sbjct: 1016 ---CSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCS---TVGSLD 1069
Query: 477 DQCQT----CPMNSLLLNTTCVKDCPEGYYADEDSNRC---------AHCHSSCRTC--- 520
QC C + C +C G++ N C C S + C
Sbjct: 1070 FQCNVNTGQCNCHPKFSGAKCT-ECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCS 1128
Query: 521 ------------EGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNST 556
EG H C CRPG F L + L C Y +T
Sbjct: 1129 DQTGQCTCKVNVEGIH---CDRCRPGKFGLDAKNPLGCSSCYCFGTTT 1173
Score = 48.9 bits (115), Expect = 2e-05
Identities = 54/232 (23%), Positives = 84/232 (36%), Gaps = 34/232 (14%)
Query: 75 CKACDSNCSSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMG----ECESCHRACET 130
C + S C+++G WC+ G + G C R C G++ QE G EC C+
Sbjct: 969 CNSFGSKSFDCEESGQCWCQPG--VTGKKCDR-CAHGYFNFQEGGCTACECSHLGNNCDP 1025
Query: 131 CTG----PGH---DECSSCQE---GLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSC 180
TG P + ++CS C G + G T F ++ CH
Sbjct: 1026 KTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKF 1085
Query: 181 KTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGADLCKKC 240
S CT C +G + + + C P + +C++ T+ C+ C C
Sbjct: 1086 -----SGAKCTECSRGHWNYPRCNLCDC---FLPGTDATTCDSETKKCSCSDQTGQC-TC 1136
Query: 241 QMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEG 292
++ EG +C G + D S C C G T C +G
Sbjct: 1137 KVNV-------EGIHCDRCRPGKFGLDAKNPLGCSSC-YCFGTTTQCSEAKG 1180
Score = 38.1 bits (87), Expect = 0.035
Identities = 52/253 (20%), Positives = 76/253 (30%), Gaps = 58/253 (22%)
Query: 348 QSCPRGFYADSHHCVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKQ 407
++CP + C H C D C+ C G + AGT+ K
Sbjct: 294 RACPLDPATNKSRCECEHNTC-------GDSCDQCCP-------GFHQKPWRAGTFLTKT 339
Query: 408 TKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVK 467
E +CH C ++ L +N RG + C + C+ C
Sbjct: 340 ECEACNCHGKAEECYYDEN--VARRNLSLNIRGKYIGGGVCINCTQ-NTAGINCETCTDG 396
Query: 468 CFHCMGPAEDQ---CQTCPMNSL-LLNTTCVKD--------------------------C 497
F G + + CQ C + + LN CVKD C
Sbjct: 397 FFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRC 456
Query: 498 PEGYYADEDSNRCA----------HCHSSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCR 547
GY D C C C E C C+ G+F L ++ C
Sbjct: 457 ARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCD 516
Query: 548 EGYYADNSTGRCE 560
E + + RC+
Sbjct: 517 E-CFCSGVSNRCQ 528
Score = 36.6 bits (83), Expect = 0.10
Identities = 44/179 (24%), Positives = 63/179 (35%), Gaps = 45/179 (25%)
Query: 128 CETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPC----HSS---- 179
C+ G C +C G LR +Q G+ L PC HSS
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLR--------SQPGGRTPGPTLGTCVPCQCNGHSSLCDP 1431
Query: 180 ----CKTC--NGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSG 233
C+ C + + C C G Y + + + C Q P + S + N + +C + G
Sbjct: 1432 ETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSN--NFSPSC-VAEG 1488
Query: 234 ADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGN-ATNCHSCE 291
D + RC + CP G E CERC+ GN +C CE
Sbjct: 1489 LD----------------DYRC-TACPRG--YEGQYCERCAPGYTGSPGNPGGSCQECE 1528
Score = 33.9 bits (76), Expect = 0.66
Identities = 60/251 (23%), Positives = 78/251 (31%), Gaps = 51/251 (20%)
Query: 69 YSEAVECK---ACDSNCSSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMG------ 119
Y A C A + + C+ N C G SC +C PGF+
Sbjct: 290 YGHARACPLDPATNKSRCECEHNTC----------GDSC-DQCCPGFHQKPWRAGTFLTK 338
Query: 120 -ECESC--HRACETC---TGPGHDECSSCQEGLQLLRGMCVHATK--------TQEEGKF 165
ECE+C H E C S G + G+C++ T+ T +G F
Sbjct: 339 TECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFF 398
Query: 166 WN-----DILRKLQPCHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGS 220
+ R QPCH C +C K A C G S
Sbjct: 399 RPKGVSPNYPRPCQPCH--CDPIGSLNEVCVKDEKHARRGLAPGSCHCKTG----FGGVS 452
Query: 221 CENCTEACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSP-CRT 279
C+ C +G CK C +E C+ C E G C RC S
Sbjct: 453 CDRCARGY---TGYPDCKACNCSGLGSK--NEDPCFGPCICKENVEGGDCSRCKSGFFNL 507
Query: 280 CEGNATNCHSC 290
E N C C
Sbjct: 508 QEDNWKGCDEC 518
Score = 33.9 bits (76), Expect = 0.66
Identities = 46/179 (25%), Positives = 63/179 (35%), Gaps = 52/179 (29%)
Query: 577 CLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALN------CLS 630
C +C F+ LRS+ P + TC C QC G +L C +
Sbjct: 1391 CEACLPGFYRLRSQPGGRTPGP-------TLGTCVPC-----QCNGHSSLCDPETSICQN 1438
Query: 631 CVWSYHLMGGICTSDCLVGEYRVGEGEKFNCEKC-----------HESCMECKGPGAKNC 679
C +H G C C +G Y + +G +C++C SC+ +G C
Sbjct: 1439 C--QHHTAGDFCER-CALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCV-AEGLDDYRC 1494
Query: 680 TLCPANLVLHMDESHCLHCC--NTSDP----PSAQEC-CD--------CQDTTDECILR 723
T CP + +C C T P S QEC CD C T C R
Sbjct: 1495 TACPRG----YEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCR 1549
Score = 32.0 bits (71), Expect = 2.5
Identities = 52/219 (23%), Positives = 74/219 (33%), Gaps = 72/219 (32%)
Query: 262 GSYAEDGICERCSSPCRTCEGNATNCHSCEG-----------GHVLHHGVCQ-------- 302
G++ CE C+ C G A C+ E G + GVC
Sbjct: 333 GTFLTKTECEACN-----CHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAG 387
Query: 303 ---ENCPERHVAVEGVCKHCPEMCQDCIHEKTCKECMPEFFLHDDMC---HQSCPRGFYA 356
E C + +GV + P CQ C C P L +++C + RG
Sbjct: 388 INCETCTDGFFRPKGVSPNYPRPCQPC-------HCDPIGSL-NEVCVKDEKHARRGLAP 439
Query: 357 DSHHC------VPC---------HKDCLECS----GPKADD-----CELCLESSWVLYDG 392
S HC V C + DC C+ G K +D C +C E+ +G
Sbjct: 440 GSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPCFGPC-ICKEN----VEG 494
Query: 393 LCLEECPAGTYYEKQTKECRDCHKSCLTCSSSGTCTTCQ 431
C +G + ++ D K C C SG CQ
Sbjct: 495 GDCSRCKSGFFNLQE-----DNWKGCDECFCSGVSNRCQ 528
Score = 30.8 bits (68), Expect = 5.6
Identities = 68/308 (22%), Positives = 105/308 (34%), Gaps = 58/308 (18%)
Query: 268 GICERCSSPCRTCEGN-ATNCHSCEGGHVLHHGVCQENCPERHVAVEGVCKHCPEM-CQD 325
G+C C R C + ATN CE H C + CP H + C+
Sbjct: 285 GMCI-CYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEA 343
Query: 326 CIHEKTCKECMPEFFLHDDMCHQSCP---RGFYADSHHCVPCHKDCLECSGPKADDCELC 382
C +EC + +++ ++ RG Y C+ C ++ +CE C
Sbjct: 344 CNCHGKAEEC----YYDENVARRNLSLNIRGKYIGGGVCINCTQN------TAGINCETC 393
Query: 383 LESSWVLYDGLCLEECPAGTYYEKQTKECRDCHKSCLTCSSSGTCTTCQK----GLIMNP 438
DG + + Y + C+ CH + S + C +K GL
Sbjct: 394 T-------DGFFRPKGVSPNY----PRPCQPCHCDPIG-SLNEVCVKDEKHARRGL---A 438
Query: 439 RGSC-----MANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQC-QTCPMNSLLLNTT 492
GSC C P CK C+ C ED C C +
Sbjct: 439 PGSCHCKTGFGGVSCDRCARGYTGYPDCKACN--CSGLGSKNEDPCFGPCICKENVEGGD 496
Query: 493 CVKDCPEGYYADEDSN--RCAHCHSSCRTCEGRHSRQCHSCRPGWFQLGKECLLQCREGY 550
C + C G++ ++ N C C C G +R C+ ++ GK +Q G+
Sbjct: 497 CSR-CKSGFFNLQEDNWKGCDECF-----CSGVSNR----CQSSYWTYGK---IQDMSGW 543
Query: 551 YADNSTGR 558
Y + GR
Sbjct: 544 YLTDLPGR 551
Score = 30.4 bits (67), Expect = 7.3
Identities = 40/165 (24%), Positives = 52/165 (31%), Gaps = 47/165 (28%)
Query: 441 SCMANEKCSPSEYWDEDAPG----------CKPCHVKCFHCM-GPAEDQCQTCPMNSLLL 489
S ++ E C P Y PG C PC + P CQ C ++
Sbjct: 1387 SGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQHHTA-- 1444
Query: 490 NTTCVKDCPEGYYA-----DEDSNRCA--------HCHSSCRTCEGRHSRQCHSCRPGWF 536
C + C GYY D +CA + SC EG +C +C G+
Sbjct: 1445 GDFCER-CALGYYGIVKGLPNDCQQCACPLISSSNNFSPSC-VAEGLDDYRCTACPRGY- 1501
Query: 537 QLGKECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCD 581
EG Y CERC G G C C+
Sbjct: 1502 -----------EGQY-------CERCAPGYTGSPGNPGGSCQECE 1528
>gi|110825958 v-erb-a erythroblastic leukemia viral oncogene homolog
4 isoform JM-a/CVT-2 precursor [Homo sapiens]
Length = 1292
Score = 64.7 bits (156), Expect = 3e-10
Identities = 47/158 (29%), Positives = 65/158 (41%), Gaps = 29/158 (18%)
Query: 547 REGYYADNSTGRCERCNRSCK--GCQGPRPTDCLSCDRFFFLLRSKGE-CHRSC---PDH 600
R+ A+N T CN C GC GP P CLSC RF S+G C SC
Sbjct: 488 RDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRF-----SRGRICIESCNLYDGE 542
Query: 601 YYVEQSTQTCERCHPTCDQ-------CKGKGALNCLSCVWSYHLMGGICTSDCLVG---- 649
+ ++ C C P C++ C G G NC C S+ G C C G
Sbjct: 543 FREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKC--SHFKDGPNCVEKCPDGLQGA 600
Query: 650 ---EYRVGEGEKFNCEKCHESCME-CKGPGAKNCTLCP 683
++ + ++ C CH +C + C GP + +C P
Sbjct: 601 NSFIFKYADPDR-ECHPCHPNCTQGCNGPTSHDCIYYP 637
Score = 55.8 bits (133), Expect = 2e-07
Identities = 56/226 (24%), Positives = 78/226 (34%), Gaps = 43/226 (19%)
Query: 507 SNRCAHCHSSCR-TCEGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNSTGRCERCNRS 565
S+ C CH SC C G C + ++C +C Y +D C C+R
Sbjct: 183 SSGCGRCHKSCTGRCWGPTENHCQTLTRT--VCAEQCDGRCYGPYVSD-----C--CHRE 233
Query: 566 CKG-CQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKG 624
C G C GP+ TDC +C F G C CP + +T E + G
Sbjct: 234 CAGGCSGPKDTDCFACMNF----NDSGACVTQCPQTFVYNPTTFQLEH---NFNAKYTYG 286
Query: 625 ALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFNCEKCHESCME-CKGPGAK------ 677
A C ++ + C C + V E C+ C + C + C G G
Sbjct: 287 AFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQ 346
Query: 678 -----------NCTLCPANLVLHMDESHCLHCCNTSDPPSAQECCD 712
NCT NL+ + H DP +A E D
Sbjct: 347 TVDSSNIDKFINCTKINGNLIFLVTGIH-------GDPYNAIEAID 385
Score = 54.3 bits (129), Expect = 5e-07
Identities = 36/127 (28%), Positives = 52/127 (40%), Gaps = 23/127 (18%)
Query: 471 CMGPAEDQCQTCPMNSLLLNTTCVKDCP--EGYYAD-EDSNRCAHCHSSCR-------TC 520
C GP DQC +C S C++ C +G + + E+ + C C C TC
Sbjct: 512 CWGPGPDQCLSCRRFS--RGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLTC 569
Query: 521 EGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNS--------TGRCERCNRSC-KGCQG 571
G C C F+ G C+ +C +G NS C C+ +C +GC G
Sbjct: 570 HGPGPDNCTKC--SHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGCNG 627
Query: 572 PRPTDCL 578
P DC+
Sbjct: 628 PTSHDCI 634
Score = 48.9 bits (115), Expect = 2e-05
Identities = 43/175 (24%), Positives = 70/175 (40%), Gaps = 31/175 (17%)
Query: 358 SHHCVPCHKDCL-ECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKQTKECRDCHK 416
S C CHK C C GP + C+ + +C E+C G Y +C CH+
Sbjct: 183 SSGCGRCHKSCTGRCWGPTENHCQTLTRT-------VCAEQCD-GRCYGPYVSDC--CHR 232
Query: 417 SCLTCSSSGTCTTCQKGLIMNPRGSCMANEKC------SPSEYWDEDAPGCKPCHVKCFH 470
C S T C + N G+C+ +C +P+ + E K +
Sbjct: 233 ECAGGCSGPKDTDCFACMNFNDSGACVT--QCPQTFVYNPTTFQLEHNFNAK--YTYGAF 288
Query: 471 CMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDS--NRCAHCHSSC-RTCEG 522
C+ + CP N ++ +++CV+ CP E++ C C C + C+G
Sbjct: 289 CV-------KKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDG 336
Score = 45.8 bits (107), Expect = 2e-04
Identities = 39/158 (24%), Positives = 55/158 (34%), Gaps = 37/158 (23%)
Query: 300 VCQENCPERHVAVEG-VCKHC----------PEMCQDCIHEKTCKECMPEFFLHDDMCHQ 348
V ++N + EG VC H P+ C C + C+ L+D +
Sbjct: 486 VIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFRE 545
Query: 349 SCPRGFYADSHHCVPCHKDC-------LECSGPKADDCELCLESSWVLYDGL-CLEECPA 400
+ + CV C C L C GP D+C C DG C+E+CP
Sbjct: 546 ------FENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFK----DGPNCVEKCPD 595
Query: 401 GTY--------YEKQTKECRDCHKSCLTCSSSGTCTTC 430
G Y +EC CH +C + T C
Sbjct: 596 GLQGANSFIFKYADPDRECHPCHPNCTQGCNGPTSHDC 633
Score = 42.4 bits (98), Expect = 0.002
Identities = 39/156 (25%), Positives = 55/156 (35%), Gaps = 14/156 (8%)
Query: 316 CKHCPEMCQDCIHEKTCKECMPEFFLHDDMCHQSCPRGFYADS-HHCVPCHKDCLE-CSG 373
C C + C T C L +C + C Y C CH++C CSG
Sbjct: 186 CGRCHKSCTGRCWGPTENHCQT---LTRTVCAEQCDGRCYGPYVSDC--CHRECAGGCSG 240
Query: 374 PKADDCELCLESSWVLYDGLCLEECPAGTYYEKQTKECRDCHKSCLTCSSSGTCT-TCQK 432
PK DC C+ + G C+ +CP Y T + H + C C
Sbjct: 241 PKDTDCFACMNFN---DSGACVTQCPQTFVYNPTTFQLE--HNFNAKYTYGAFCVKKCPH 295
Query: 433 GLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKC 468
+++ SC+ S E + CKPC C
Sbjct: 296 NFVVD-SSSCVRACPSSKMEVEENGIKMCKPCTDIC 330
Score = 42.0 bits (97), Expect = 0.002
Identities = 54/229 (23%), Positives = 76/229 (33%), Gaps = 55/229 (24%)
Query: 166 WNDILRKLQPCHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCT 225
W DI+R P + + + NGS+ C C K SC W G EN
Sbjct: 163 WQDIVRNPWPSNLTLVSTNGSSG-CGRCHK-----------SCTGRCW-----GPTENHC 205
Query: 226 EACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNAT 285
+ A+ C +GRCY G Y D C+ C + T
Sbjct: 206 QTLTRTVCAEQC--------------DGRCY-----GPYVSDCCHRECAGGCSGPKD--T 244
Query: 286 NCHSCEGGHVLHHGVCQENCPERHVAVEGVCKHCPEMCQDCIHEKTCKECMPEFFLHDDM 345
+C +C + G C CP+ V + P Q H K + +
Sbjct: 245 DCFACMNFN--DSGACVTQCPQTFV-------YNPTTFQ-LEHNFNAK------YTYGAF 288
Query: 346 CHQSCPRGFYADSHHCV-PCHKDCLECSGPKADDCELCLESSWVLYDGL 393
C + CP F DS CV C +E C+ C + DG+
Sbjct: 289 CVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGI 337
Score = 41.2 bits (95), Expect = 0.004
Identities = 41/174 (23%), Positives = 60/174 (34%), Gaps = 31/174 (17%)
Query: 554 NSTGRCERCNRSCKG-CQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCER 612
N + C RC++SC G C GP C + R + G C+ +
Sbjct: 181 NGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCY-----------GPYVSDC 229
Query: 613 CHPTC-DQCKGKGALNCLSCVWSYHLMGGICTSDC----LVGEYRVGEGEKFNCEKCHES 667
CH C C G +C +C+ G C + C + FN + +
Sbjct: 230 CHRECAGGCSGPKDTDCFACM--NFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTY-- 285
Query: 668 CMECKGPGAKNCTLCPANLVLHMDESHCLHCCNTSDPPSAQECCD-CQDTTDEC 720
GA CP N V +D S C+ C +S + C+ TD C
Sbjct: 286 -------GAFCVKKCPHNFV--VDSSSCVRACPSSKMEVEENGIKMCKPCTDIC 330
Score = 40.8 bits (94), Expect = 0.005
Identities = 39/137 (28%), Positives = 55/137 (40%), Gaps = 20/137 (14%)
Query: 66 EKTYSEAVECK-ACDSN-CSSCDQNGCYWCEEGFFLLGGSCVRKCG--PGFYGDQEMGE- 120
E +E + C C S+ C + C C F G C+ C G + + E G
Sbjct: 494 ENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRR--FSRGRICIESCNLYDGEFREFENGSI 551
Query: 121 CESCHRACE-------TCTGPGHDECSSC---QEGLQLLRGMCVHATKTQEEGKF-WNDI 169
C C CE TC GPG D C+ C ++G + C + F + D
Sbjct: 552 CVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVE-KCPDGLQGANSFIFKYADP 610
Query: 170 LRKLQPCHSSC-KTCNG 185
R+ PCH +C + CNG
Sbjct: 611 DRECHPCHPNCTQGCNG 627
Score = 40.8 bits (94), Expect = 0.005
Identities = 25/80 (31%), Positives = 31/80 (38%), Gaps = 13/80 (16%)
Query: 459 PGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTTCVKDCPEGY---------YADEDSNR 509
P C+ C GP D C C + CV+ CP+G YAD D
Sbjct: 557 PQCEKMEDGLLTCHGPGPDNCTKC--SHFKDGPNCVEKCPDGLQGANSFIFKYADPD-RE 613
Query: 510 CAHCHSSC-RTCEGRHSRQC 528
C CH +C + C G S C
Sbjct: 614 CHPCHPNCTQGCNGPTSHDC 633
Score = 40.0 bits (92), Expect = 0.009
Identities = 43/174 (24%), Positives = 58/174 (33%), Gaps = 54/174 (31%)
Query: 124 CHRACET--CTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSCK 181
C+ C + C GPG D+C SC+ + RG + +G+F R+ +
Sbjct: 503 CNHLCSSDGCWGPGPDQCLSCR---RFSRGRICIESCNLYDGEF-----REFE------- 547
Query: 182 TCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGA--DLCKK 239
NGS CV PQ CE + C G D C K
Sbjct: 548 --NGSI----------------CVECDPQ----------CEKMEDGLLTCHGPGPDNCTK 579
Query: 240 CQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNC-HSCEG 292
C P C KCP+G + + + P R C NC C G
Sbjct: 580 CSHFKDGP------NCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGCNG 627
>gi|4885215 v-erb-a erythroblastic leukemia viral oncogene homolog 4
isoform JM-a/CVT-1 precursor [Homo sapiens]
Length = 1308
Score = 64.7 bits (156), Expect = 3e-10
Identities = 47/158 (29%), Positives = 65/158 (41%), Gaps = 29/158 (18%)
Query: 547 REGYYADNSTGRCERCNRSCK--GCQGPRPTDCLSCDRFFFLLRSKGE-CHRSC---PDH 600
R+ A+N T CN C GC GP P CLSC RF S+G C SC
Sbjct: 488 RDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRF-----SRGRICIESCNLYDGE 542
Query: 601 YYVEQSTQTCERCHPTCDQ-------CKGKGALNCLSCVWSYHLMGGICTSDCLVG---- 649
+ ++ C C P C++ C G G NC C S+ G C C G
Sbjct: 543 FREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKC--SHFKDGPNCVEKCPDGLQGA 600
Query: 650 ---EYRVGEGEKFNCEKCHESCME-CKGPGAKNCTLCP 683
++ + ++ C CH +C + C GP + +C P
Sbjct: 601 NSFIFKYADPDR-ECHPCHPNCTQGCNGPTSHDCIYYP 637
Score = 55.8 bits (133), Expect = 2e-07
Identities = 56/226 (24%), Positives = 78/226 (34%), Gaps = 43/226 (19%)
Query: 507 SNRCAHCHSSCR-TCEGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNSTGRCERCNRS 565
S+ C CH SC C G C + ++C +C Y +D C C+R
Sbjct: 183 SSGCGRCHKSCTGRCWGPTENHCQTLTRT--VCAEQCDGRCYGPYVSD-----C--CHRE 233
Query: 566 CKG-CQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKG 624
C G C GP+ TDC +C F G C CP + +T E + G
Sbjct: 234 CAGGCSGPKDTDCFACMNF----NDSGACVTQCPQTFVYNPTTFQLEH---NFNAKYTYG 286
Query: 625 ALNCLSCVWSYHLMGGICTSDCLVGEYRVGEGEKFNCEKCHESCME-CKGPGAK------ 677
A C ++ + C C + V E C+ C + C + C G G
Sbjct: 287 AFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQ 346
Query: 678 -----------NCTLCPANLVLHMDESHCLHCCNTSDPPSAQECCD 712
NCT NL+ + H DP +A E D
Sbjct: 347 TVDSSNIDKFINCTKINGNLIFLVTGIH-------GDPYNAIEAID 385
Score = 54.3 bits (129), Expect = 5e-07
Identities = 36/127 (28%), Positives = 52/127 (40%), Gaps = 23/127 (18%)
Query: 471 CMGPAEDQCQTCPMNSLLLNTTCVKDCP--EGYYAD-EDSNRCAHCHSSCR-------TC 520
C GP DQC +C S C++ C +G + + E+ + C C C TC
Sbjct: 512 CWGPGPDQCLSCRRFS--RGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLTC 569
Query: 521 EGRHSRQCHSCRPGWFQLGKECLLQCREGYYADNS--------TGRCERCNRSC-KGCQG 571
G C C F+ G C+ +C +G NS C C+ +C +GC G
Sbjct: 570 HGPGPDNCTKC--SHFKDGPNCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGCNG 627
Query: 572 PRPTDCL 578
P DC+
Sbjct: 628 PTSHDCI 634
Score = 48.9 bits (115), Expect = 2e-05
Identities = 43/175 (24%), Positives = 70/175 (40%), Gaps = 31/175 (17%)
Query: 358 SHHCVPCHKDCL-ECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKQTKECRDCHK 416
S C CHK C C GP + C+ + +C E+C G Y +C CH+
Sbjct: 183 SSGCGRCHKSCTGRCWGPTENHCQTLTRT-------VCAEQCD-GRCYGPYVSDC--CHR 232
Query: 417 SCLTCSSSGTCTTCQKGLIMNPRGSCMANEKC------SPSEYWDEDAPGCKPCHVKCFH 470
C S T C + N G+C+ +C +P+ + E K +
Sbjct: 233 ECAGGCSGPKDTDCFACMNFNDSGACVT--QCPQTFVYNPTTFQLEHNFNAK--YTYGAF 288
Query: 471 CMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDS--NRCAHCHSSC-RTCEG 522
C+ + CP N ++ +++CV+ CP E++ C C C + C+G
Sbjct: 289 CV-------KKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDG 336
Score = 45.8 bits (107), Expect = 2e-04
Identities = 39/158 (24%), Positives = 55/158 (34%), Gaps = 37/158 (23%)
Query: 300 VCQENCPERHVAVEG-VCKHC----------PEMCQDCIHEKTCKECMPEFFLHDDMCHQ 348
V ++N + EG VC H P+ C C + C+ L+D +
Sbjct: 486 VIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFRE 545
Query: 349 SCPRGFYADSHHCVPCHKDC-------LECSGPKADDCELCLESSWVLYDGL-CLEECPA 400
+ + CV C C L C GP D+C C DG C+E+CP
Sbjct: 546 ------FENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFK----DGPNCVEKCPD 595
Query: 401 GTY--------YEKQTKECRDCHKSCLTCSSSGTCTTC 430
G Y +EC CH +C + T C
Sbjct: 596 GLQGANSFIFKYADPDRECHPCHPNCTQGCNGPTSHDC 633
Score = 42.4 bits (98), Expect = 0.002
Identities = 39/156 (25%), Positives = 55/156 (35%), Gaps = 14/156 (8%)
Query: 316 CKHCPEMCQDCIHEKTCKECMPEFFLHDDMCHQSCPRGFYADS-HHCVPCHKDCLE-CSG 373
C C + C T C L +C + C Y C CH++C CSG
Sbjct: 186 CGRCHKSCTGRCWGPTENHCQT---LTRTVCAEQCDGRCYGPYVSDC--CHRECAGGCSG 240
Query: 374 PKADDCELCLESSWVLYDGLCLEECPAGTYYEKQTKECRDCHKSCLTCSSSGTCT-TCQK 432
PK DC C+ + G C+ +CP Y T + H + C C
Sbjct: 241 PKDTDCFACMNFN---DSGACVTQCPQTFVYNPTTFQLE--HNFNAKYTYGAFCVKKCPH 295
Query: 433 GLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKC 468
+++ SC+ S E + CKPC C
Sbjct: 296 NFVVD-SSSCVRACPSSKMEVEENGIKMCKPCTDIC 330
Score = 42.0 bits (97), Expect = 0.002
Identities = 54/229 (23%), Positives = 76/229 (33%), Gaps = 55/229 (24%)
Query: 166 WNDILRKLQPCHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCT 225
W DI+R P + + + NGS+ C C K SC W G EN
Sbjct: 163 WQDIVRNPWPSNLTLVSTNGSSG-CGRCHK-----------SCTGRCW-----GPTENHC 205
Query: 226 EACAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNAT 285
+ A+ C +GRCY G Y D C+ C + T
Sbjct: 206 QTLTRTVCAEQC--------------DGRCY-----GPYVSDCCHRECAGGCSGPKD--T 244
Query: 286 NCHSCEGGHVLHHGVCQENCPERHVAVEGVCKHCPEMCQDCIHEKTCKECMPEFFLHDDM 345
+C +C + G C CP+ V + P Q H K + +
Sbjct: 245 DCFACMNFN--DSGACVTQCPQTFV-------YNPTTFQ-LEHNFNAK------YTYGAF 288
Query: 346 CHQSCPRGFYADSHHCV-PCHKDCLECSGPKADDCELCLESSWVLYDGL 393
C + CP F DS CV C +E C+ C + DG+
Sbjct: 289 CVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGI 337
Score = 41.2 bits (95), Expect = 0.004
Identities = 41/174 (23%), Positives = 60/174 (34%), Gaps = 31/174 (17%)
Query: 554 NSTGRCERCNRSCKG-CQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCER 612
N + C RC++SC G C GP C + R + G C+ +
Sbjct: 181 NGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCY-----------GPYVSDC 229
Query: 613 CHPTC-DQCKGKGALNCLSCVWSYHLMGGICTSDC----LVGEYRVGEGEKFNCEKCHES 667
CH C C G +C +C+ G C + C + FN + +
Sbjct: 230 CHRECAGGCSGPKDTDCFACM--NFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTY-- 285
Query: 668 CMECKGPGAKNCTLCPANLVLHMDESHCLHCCNTSDPPSAQECCD-CQDTTDEC 720
GA CP N V +D S C+ C +S + C+ TD C
Sbjct: 286 -------GAFCVKKCPHNFV--VDSSSCVRACPSSKMEVEENGIKMCKPCTDIC 330
Score = 40.8 bits (94), Expect = 0.005
Identities = 39/137 (28%), Positives = 55/137 (40%), Gaps = 20/137 (14%)
Query: 66 EKTYSEAVECK-ACDSN-CSSCDQNGCYWCEEGFFLLGGSCVRKCG--PGFYGDQEMGE- 120
E +E + C C S+ C + C C F G C+ C G + + E G
Sbjct: 494 ENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRR--FSRGRICIESCNLYDGEFREFENGSI 551
Query: 121 CESCHRACE-------TCTGPGHDECSSC---QEGLQLLRGMCVHATKTQEEGKF-WNDI 169
C C CE TC GPG D C+ C ++G + C + F + D
Sbjct: 552 CVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVE-KCPDGLQGANSFIFKYADP 610
Query: 170 LRKLQPCHSSC-KTCNG 185
R+ PCH +C + CNG
Sbjct: 611 DRECHPCHPNCTQGCNG 627
Score = 40.8 bits (94), Expect = 0.005
Identities = 25/80 (31%), Positives = 31/80 (38%), Gaps = 13/80 (16%)
Query: 459 PGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTTCVKDCPEGY---------YADEDSNR 509
P C+ C GP D C C + CV+ CP+G YAD D
Sbjct: 557 PQCEKMEDGLLTCHGPGPDNCTKC--SHFKDGPNCVEKCPDGLQGANSFIFKYADPD-RE 613
Query: 510 CAHCHSSC-RTCEGRHSRQC 528
C CH +C + C G S C
Sbjct: 614 CHPCHPNCTQGCNGPTSHDC 633
Score = 40.0 bits (92), Expect = 0.009
Identities = 43/174 (24%), Positives = 58/174 (33%), Gaps = 54/174 (31%)
Query: 124 CHRACET--CTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQPCHSSCK 181
C+ C + C GPG D+C SC+ + RG + +G+F R+ +
Sbjct: 503 CNHLCSSDGCWGPGPDQCLSCR---RFSRGRICIESCNLYDGEF-----REFE------- 547
Query: 182 TCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSGA--DLCKK 239
NGS CV PQ CE + C G D C K
Sbjct: 548 --NGSI----------------CVECDPQ----------CEKMEDGLLTCHGPGPDNCTK 579
Query: 240 CQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNC-HSCEG 292
C P C KCP+G + + + P R C NC C G
Sbjct: 580 CSHFKDGP------NCVEKCPDGLQGANSFIFKYADPDRECHPCHPNCTQGCNG 627
>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
Length = 1575
Score = 63.9 bits (154), Expect = 6e-10
Identities = 97/449 (21%), Positives = 136/449 (30%), Gaps = 132/449 (29%)
Query: 102 GSCVRKCGPGFYGDQEMGECESCHRACETCTGPGHDECSSCQEGLQLLRGMCVHATKTQE 161
G C PG+ + G + +C CT H C G+CV + T+
Sbjct: 681 GQFCESCAPGYKREMPQG---GPYASCVPCTCNQHGTCDPNT-------GICVCSHHTEG 730
Query: 162 EGKFWNDILRKLQPCHSSCKTC---------NGSATLCTSCPKGAYLLAQACVSSCPQGT 212
SC+ C G A C CP C T
Sbjct: 731 P----------------SCERCLPGFYGNPFAGQADDCQPCP---------CPGQSACTT 765
Query: 213 WPSVRSGSCENCTEA-----CAICSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAED 267
P R C +C C +C + GHP H+ +C +
Sbjct: 766 IPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLF-GHPQPCHQCQCSGNVDPNAV--- 821
Query: 268 GICERCSSPCRTCEGNATNCHSCEGGHVLHHGVCQENCPERHVAVEGVCKHCPE-MCQDC 326
G C+ S C C N T H C+HC E
Sbjct: 822 GNCDPLSGHCLRCLHNTTGDH---------------------------CEHCQEGFYGSA 854
Query: 327 IHEKTCKECMPEFFLHDDMCHQSCPRGFYADSHHCVPCHKDCLECSGPKADDCELCLESS 386
+ + +CMP CH P+G ++ C P C A DC C
Sbjct: 855 LAPRPADKCMP------CSCH---PQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGF 905
Query: 387 WVLYDGLCLEEC---PAGTYYEKQTKECRDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCM 443
+ L G C P G+ ++ CH +G CT C+ G+ C
Sbjct: 906 FDLQPGRGCRSCKCHPLGSQEDQ-------CHPK------TGQCT-CRPGVTGQACDRCQ 951
Query: 444 ANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYA 503
++ GC+ C +G A QC N TCV C G+
Sbjct: 952 LG-------FFGFSIKGCRACRCSP---LGAASAQCHE--------NGTCV--CRPGF-- 989
Query: 504 DEDSNRCAHCHSSC-RTCEGRHSRQCHSC 531
+ +C CH + T +G H +QC SC
Sbjct: 990 --EGYKCDRCHDNFFLTADGTHCQQCPSC 1016
Score = 60.5 bits (145), Expect = 7e-09
Identities = 85/353 (24%), Positives = 114/353 (32%), Gaps = 109/353 (30%)
Query: 69 YSEAVECKACDSNCSSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMGECESCHRAC 128
Y+ V C C+ + +CD N C G SC R C PGFYG+ G+ + C
Sbjct: 701 YASCVPC-TCNQH-GTCDPNTGI-CVCSHHTEGPSCER-CLPGFYGNPFAGQADD----C 752
Query: 129 ETCTGPGHDECSSCQEGLQLLRGMCVHATKTQE-------EGKFWNDILRKL---QPCH- 177
+ C PG C++ E ++ +C H Q + F+ D L QPCH
Sbjct: 753 QPCPCPGQSACTTIPESREV---VCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQ 809
Query: 178 -------------------SSCKTC--NGSATLCTSCPKGAY--LLAQACVSSC------ 208
C C N + C C +G Y LA C
Sbjct: 810 CQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCH 869
Query: 209 PQGT----------------WPSVRSGSCENCTEACAICSGADLCKKCQMQPGHPLFLHE 252
PQG+ P V + C C C+ C+ HPL E
Sbjct: 870 PQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKC---HPLGSQE 926
Query: 253 GRCYSK-----CPEGSYAEDGICERCS--------SPCRTCEGNATNCHSCEGGHVLHHG 299
+C+ K C G + C+RC CR C + S +
Sbjct: 927 DQCHPKTGQCTCRPGVTGQ--ACDRCQLGFFGFSIKGCRACRCSPLGAASAQ-------- 976
Query: 300 VCQENCPERHVAVEGVCKHCPEMCQDCIHEKTCKECMPEFFLHDDMCH-QSCP 351
C EN G C +C+ C C FFL D H Q CP
Sbjct: 977 -CHEN---------GTC-----VCRPGFEGYKCDRCHDNFFLTADGTHCQQCP 1014
Score = 57.4 bits (137), Expect = 6e-08
Identities = 89/377 (23%), Positives = 126/377 (33%), Gaps = 80/377 (21%)
Query: 374 PKADDCELCLESSWVLYDGLCLEECPAGTYYEKQTKECRDCHKSCL--TCSSSGTCTTCQ 431
P A E+C S Y G E C G Y+++ + + SC+ TC+ GTC
Sbjct: 665 PPASWVEIC--SCPTGYTGQFCESCAPG--YKREMPQGGP-YASCVPCTCNQHGTCDPNT 719
Query: 432 KGLIMNPRGSCMANEKCSPSEYWDE---DAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLL 488
+ + + E+C P Y + A C+PC P + C T P + +
Sbjct: 720 GICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPC-------PGQSACTTIPESREV 772
Query: 489 LNTTC--------VKDCPEGYYADE-----DSNRCAHCHSS----------CRTCEGRHS 525
+ T C + C +G++ D C C S C G
Sbjct: 773 VCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCL 832
Query: 526 RQCHSCRPGWFQLGKECLLQCREGYY----ADNSTGRCERCNRSCKGCQG---------- 571
R H+ G C C+EG+Y A +C C+ +G
Sbjct: 833 RCLHNTT------GDHCE-HCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTG 885
Query: 572 -----PRPT--DCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKG 624
P T DC C FF L+ C RSC H Q Q CHP QC +
Sbjct: 886 QCSCLPHVTARDCSRCYPGFFDLQPGRGC-RSCKCHPLGSQEDQ----CHPKTGQCTCRP 940
Query: 625 ALNCLSCVWSYHLMGGICTSDCLVGEYR-VGEGEKFNCEKCHES--CMECKGPGAKNCTL 681
+ +C G C +G +CHE+ C+ G C
Sbjct: 941 GVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASA----QCHENGTCVCRPGFEGYKCDR 996
Query: 682 CPANLVLHMDESHCLHC 698
C N L D +HC C
Sbjct: 997 CHDNFFLTADGTHCQQC 1013
Score = 45.4 bits (106), Expect = 2e-04
Identities = 60/259 (23%), Positives = 83/259 (32%), Gaps = 69/259 (26%)
Query: 292 GGHVLHHGVCQENCPERHVAVEGVCKHCPEMCQDCIHEKTCKECMPEFFLHDDMCHQSCP 351
GG +G E P+ VA + C+ CQ C+ C+P F D +
Sbjct: 268 GGRCKCNGHASECGPD--VAGQLACR-----CQHNTTGTDCERCLP--FFQD----RPWA 314
Query: 352 RGFYADSHHCVPCHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKQTKEC 411
RG +H C+PC+ CSG EEC + T
Sbjct: 315 RGTAEAAHECLPCN-----CSGRS--------------------EECTFDRELFRSTGHG 349
Query: 412 RDCHKSCLTCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHC 471
CH C ++ C CQ+ +WD P C+PC +
Sbjct: 350 GRCHH-CRDHTAGPHCERCQENFY-----------------HWDPRMP-CQPCDCQSAGS 390
Query: 472 MGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCH--SSCRTCEGRHSR--- 526
+ D TC + C + P + E R C+ S TC+ R R
Sbjct: 391 LHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDTCDPRSGRCPC 450
Query: 527 -------QCHSCRPGWFQL 538
C CRPG F L
Sbjct: 451 KENVEGNLCDRCRPGTFNL 469
Score = 38.9 bits (89), Expect = 0.020
Identities = 59/241 (24%), Positives = 78/241 (32%), Gaps = 44/241 (18%)
Query: 69 YSEAVECKACDSNCSSC--DQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEM--GECESC 124
+S CK C+ + S C D G C G C R C P F+ D+ G E+
Sbjct: 265 FSVGGRCK-CNGHASECGPDVAGQLACRCQHNTTGTDCER-CLP-FFQDRPWARGTAEAA 321
Query: 125 HRACETCTGPGHDECSSCQEGLQLLR-----GMC---------VHATKTQEEGKFWNDIL 170
H C C G E C +L R G C H + QE W D
Sbjct: 322 HE-CLPCNCSGRSE--ECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHW-DPR 377
Query: 171 RKLQPCHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAI 230
QPC C + +L C + P+V C+ C
Sbjct: 378 MPCQPCD-----CQSAGSLHLQCDDTGTCACK-----------PTVTGWKCDRCLPGFHS 421
Query: 231 CSGADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCE-GNATNCHS 289
S C+ C P L + R +CP E +C+RC + N C S
Sbjct: 422 LSEGG-CRPCTCNPAGSLDTCDPRS-GRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSS 479
Query: 290 C 290
C
Sbjct: 480 C 480
Score = 31.6 bits (70), Expect = 3.3
Identities = 50/201 (24%), Positives = 64/201 (31%), Gaps = 22/201 (10%)
Query: 457 DAPGCKPCHVKCFHCMGPAEDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHC--H 514
D C P G AE + P N + C D E + + RC HC H
Sbjct: 300 DCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFD-RELFRSTGHGGRCHHCRDH 358
Query: 515 SSCRTCEGRHSRQCH-----SCRPGWFQLGKECLLQCRE-GYYADNSTGRCERCNRSCKG 568
++ CE H C+P Q LQC + G A T +C+R G
Sbjct: 359 TAGPHCERCQENFYHWDPRMPCQPCDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPG 418
Query: 569 CQ-----GPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGK 623
G RP C G C P VE + C+RC P +
Sbjct: 419 FHSLSEGGCRPCTCNPAGSLDTCDPRSGRC----PCKENVEGNL--CDRCRPGTFNLQPH 472
Query: 624 GALNCLSCVWSYHLMGGICTS 644
C SC H +C S
Sbjct: 473 NPAGCSSCFCYGH--SKVCAS 491
>gi|29725609 epidermal growth factor receptor isoform a precursor
[Homo sapiens]
Length = 1210
Score = 63.2 bits (152), Expect = 1e-09
Identities = 51/178 (28%), Positives = 74/178 (41%), Gaps = 37/178 (20%)
Query: 528 CHSCRPGWFQL----GKECLLQCREGYYADNSTGRCERCNRSCKGCQGPRPTDCLSCDRF 583
C++ W +L G++ + G + +TG+ S +GC GP P DC+SC
Sbjct: 470 CYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNV 529
Query: 584 FFLLRSKG-ECHRSC-----PDHYYVEQSTQTCERCHPTC------DQCKGKGALNCLSC 631
S+G EC C +VE S C +CHP C C G+G NC+ C
Sbjct: 530 -----SRGRECVDKCNLLEGEPREFVENS--ECIQCHPECLPQAMNITCTGRGPDNCIQC 582
Query: 632 VWSYHLMGGICTSDCLVGEYRVGEGEKF---------NCEKCHESC-MECKGPGAKNC 679
++++ G C C G +GE C CH +C C GPG + C
Sbjct: 583 --AHYIDGPHCVKTCPAGV--MGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGC 636
Score = 51.6 bits (122), Expect = 3e-06
Identities = 40/139 (28%), Positives = 54/139 (38%), Gaps = 31/139 (22%)
Query: 513 CHSSCRT--CEGRHSRQCHSCRPGWFQLGKECLLQCR--EG---YYADNSTGRCERCNRS 565
CH+ C C G R C SCR G+EC+ +C EG + +NS C +C+
Sbjct: 506 CHALCSPEGCWGPEPRDCVSCRN--VSRGRECVDKCNLLEGEPREFVENS--ECIQCHPE 561
Query: 566 CK------GCQGPRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQST---------QTC 610
C C G P +C+ C + C ++CP E +T C
Sbjct: 562 CLPQAMNITCTGRGPDNCIQCAHYI----DGPHCVKTCPAGVMGENNTLVWKYADAGHVC 617
Query: 611 ERCHPTCDQ-CKGKGALNC 628
CHP C C G G C
Sbjct: 618 HLCHPNCTYGCTGPGLEGC 636
Score = 51.2 bits (121), Expect = 4e-06
Identities = 46/169 (27%), Positives = 66/169 (39%), Gaps = 27/169 (15%)
Query: 524 HSRQCHSCRPGW-----FQLGKECLLQCREGYYADNSTGRC------ERCNRSCK-GCQG 571
H C C P + G+E + + A +GRC + C+ C GC G
Sbjct: 183 HLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTG 242
Query: 572 PRPTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGK---GALNC 628
PR +DCL C +F R + C +CP +T + +P +GK GA
Sbjct: 243 PRESDCLVCRKF----RDEATCKDTCPPLMLYNPTTYQMD-VNP-----EGKYSFGATCV 292
Query: 629 LSCVWSYHLMG-GICTSDCLVGEYRVGEGEKFNCEKCHESCME-CKGPG 675
C +Y + G C C Y + E C+KC C + C G G
Sbjct: 293 KKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIG 341
Score = 48.5 bits (114), Expect = 3e-05
Identities = 46/174 (26%), Positives = 67/174 (38%), Gaps = 27/174 (15%)
Query: 118 MGECESCHRACE--TCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRKLQP 175
+G C+ C +C +C G G + C +L + +C + GK +D
Sbjct: 184 LGSCQKCDPSCPNGSCWGAGEENCQ------KLTKIICAQQCSGRCRGKSPSDC------ 231
Query: 176 CHSSCKT-CNGSATL-CTSCPKGAYLLAQACVSSCPQGTWPSVRSGSCENCTEACAICSG 233
CH+ C C G C C K + C +CP + + + E G
Sbjct: 232 CHNQCAAGCTGPRESDCLVCRK--FRDEATCKDTCPPLMLYNPTTYQMDVNPEG-KYSFG 288
Query: 234 ADLCKKCQMQPGHPLFLHEGRCYSKCPEGSYA--EDGI--CERCSSPCR-TCEG 282
A KKC P + + G C C SY EDG+ C++C PCR C G
Sbjct: 289 ATCVKKC---PRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNG 339
Score = 45.4 bits (106), Expect = 2e-04
Identities = 40/149 (26%), Positives = 57/149 (38%), Gaps = 39/149 (26%)
Query: 288 HSCEGGHVLHHGVCQENCPERHVAVEGVCKHCPEMCQDCIHEKTCKECMPEFFLHDDMCH 347
+SC+ + H +C EG P C C + +EC+ D C+
Sbjct: 497 NSCKATGQVCHALCSP---------EGCWGPEPRDCVSCRNVSRGRECV-------DKCN 540
Query: 348 --QSCPRGFYADSHHCVPCHKDCL------ECSGPKADDCELCLESSWVLYDG-LCLEEC 398
+ PR F +S C+ CH +CL C+G D+C C DG C++ C
Sbjct: 541 LLEGEPREFVENSE-CIQCHPECLPQAMNITCTGRGPDNCIQCAH----YIDGPHCVKTC 595
Query: 399 PAGTYYEKQT---------KECRDCHKSC 418
PAG E T C CH +C
Sbjct: 596 PAGVMGENNTLVWKYADAGHVCHLCHPNC 624
Score = 38.5 bits (88), Expect = 0.027
Identities = 39/193 (20%), Positives = 59/193 (30%), Gaps = 49/193 (25%)
Query: 361 CVPCHKDCLE--CSGPKADDCELCLESSWVLYDGLCLEECPAGTYYEKQTKECRDCHKSC 418
C C C C G ++C+ + +C ++C +G K +C CH C
Sbjct: 187 CQKCDPSCPNGSCWGAGEENCQKLTKI-------ICAQQC-SGRCRGKSPSDC--CHNQC 236
Query: 419 L---TCSSSGTCTTCQKGLIMNPRGSCMANEKCSPSEYWDEDAPGCKPCHVKCFHCMGPA 475
T C C+K R + C P ++ P
Sbjct: 237 AAGCTGPRESDCLVCRKF-----RDEATCKDTCPPLMLYN------------------PT 273
Query: 476 EDQCQTCPMNSLLLNTTCVKDCPEGYYADEDSNRCAHCHS-----------SCRTCEGRH 524
Q P TCVK CP Y + + C + C+ CEG
Sbjct: 274 TYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPC 333
Query: 525 SRQCHSCRPGWFQ 537
+ C+ G F+
Sbjct: 334 RKVCNGIGIGEFK 346
Score = 36.2 bits (82), Expect = 0.13
Identities = 39/137 (28%), Positives = 48/137 (35%), Gaps = 26/137 (18%)
Query: 75 CKACDSNCSS-CDQNGCYWCEEGFFLL------GGSCVRKCGPGFYGDQ----EMGECES 123
CKA C + C GC+ E + G CV KC G+ E EC
Sbjct: 499 CKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNL-LEGEPREFVENSECIQ 557
Query: 124 CHRACE------TCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFW--NDILRKLQP 175
CH C TCTG G D C C + H KT G N ++ K
Sbjct: 558 CHPECLPQAMNITCTGRGPDNCIQCAHYID-----GPHCVKTCPAGVMGENNTLVWKYAD 612
Query: 176 CHSSCKTCNGSATL-CT 191
C C+ + T CT
Sbjct: 613 AGHVCHLCHPNCTYGCT 629
Score = 35.8 bits (81), Expect = 0.17
Identities = 37/137 (27%), Positives = 48/137 (35%), Gaps = 23/137 (16%)
Query: 364 CHKDCLE--CSGPKADDCELCLESSWVLYDGLCLEECPA--GTYYE-KQTKECRDCHKSC 418
CH C C GP+ DC C S C+++C G E + EC CH C
Sbjct: 506 CHALCSPEGCWGPEPRDCVSCRNVS---RGRECVDKCNLLEGEPREFVENSECIQCHPEC 562
Query: 419 L------TCSSSG--TCTTCQKGL-----IMNPRGSCMANEKCSPSEYWDEDAPGCKPCH 465
L TC+ G C C + + M +Y D C CH
Sbjct: 563 LPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADA-GHVCHLCH 621
Query: 466 VKC-FHCMGPAEDQCQT 481
C + C GP + C T
Sbjct: 622 PNCTYGCTGPGLEGCPT 638
Score = 34.3 bits (77), Expect = 0.50
Identities = 41/177 (23%), Positives = 62/177 (35%), Gaps = 44/177 (24%)
Query: 254 RCYSKCPEGSY--AEDGICER-----CSSPCR-TCEGNATNCHSCEGGHVLHHGVCQENC 305
+C CP GS A + C++ C+ C C G + + C H C C
Sbjct: 189 KCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPS-DCC-------HNQCAAGC 240
Query: 306 PERHVAVEGVCKHCPEMCQDCIHEKTCKECMPEFFLHDDMCHQS--CPRGFYADSHHCVP 363
E C +C+ E TCK+ P L++ +Q P G Y+ CV
Sbjct: 241 TGPR---ESDCL----VCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCV- 292
Query: 364 CHKDCLECSGPKADDCELCLESSWVLYDGLCLEECPAGTY--YEKQTKECRDCHKSC 418
+ C + V G C+ C A +Y E ++C+ C C
Sbjct: 293 ----------------KKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPC 333
Score = 33.5 bits (75), Expect = 0.86
Identities = 26/78 (33%), Positives = 30/78 (38%), Gaps = 18/78 (23%)
Query: 65 PEKTYSEAVEC-KACDSNCSSCDQNGCYWCEEGFFLLGGSCVRKCGPGFYGDQEMG--EC 121
PE YS C K C N D GSCVR CG Y +E G +C
Sbjct: 281 PEGKYSFGATCVKKCPRNYVVTDH--------------GSCVRACGADSYEMEEDGVRKC 326
Query: 122 ESCHRAC-ETCTGPGHDE 138
+ C C + C G G E
Sbjct: 327 KKCEGPCRKVCNGIGIGE 344
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.136 0.479
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,596,466
Number of Sequences: 37866
Number of extensions: 2577892
Number of successful extensions: 10526
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 50
Number of HSP's successfully gapped in prelim test: 468
Number of HSP's that attempted gapping in prelim test: 6932
Number of HSP's gapped (non-prelim): 2135
length of query: 853
length of database: 18,247,518
effective HSP length: 111
effective length of query: 742
effective length of database: 14,044,392
effective search space: 10420938864
effective search space used: 10420938864
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.