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Search of human proteins with 239754327
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239754327 PREDICTED: chromosome 6 open reading frame 132
[Homo sapiens]
(1188 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 2455 0.0
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 2455 0.0
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 2455 0.0
gi|163965366 nascent polypeptide-associated complex alpha subuni... 159 1e-38
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 154 6e-37
gi|116284392 mucin 2 precursor [Homo sapiens] 148 3e-35
gi|160707881 formin 2 [Homo sapiens] 137 5e-32
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 133 1e-30
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 124 4e-28
gi|47132519 Ras association and pleckstrin homology domains 1 is... 122 2e-27
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 119 1e-26
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 119 1e-26
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 119 1e-26
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 119 1e-26
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 110 1e-23
gi|110349719 titin isoform N2-A [Homo sapiens] 108 2e-23
gi|150170670 piccolo isoform 2 [Homo sapiens] 107 7e-23
gi|150378539 piccolo isoform 1 [Homo sapiens] 107 7e-23
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 107 9e-23
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 105 3e-22
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 103 1e-21
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 103 1e-21
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 101 5e-21
gi|110832843 TBP-associated factor 4 [Homo sapiens] 101 5e-21
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 100 6e-21
gi|221139926 NHS-like 1 [Homo sapiens] 96 3e-19
gi|55750053 atrophin-1 [Homo sapiens] 96 3e-19
gi|55750041 atrophin-1 [Homo sapiens] 96 3e-19
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 95 3e-19
gi|153792074 proline rich 12 [Homo sapiens] 95 3e-19
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 2455 bits (6362), Expect = 0.0
Identities = 1188/1188 (100%), Positives = 1188/1188 (100%)
Query: 1 MKKKQTVQGTFSKLFGKKHTTTPSTSLYATNPPWIFTQEAPEEGTGGFDGIYYGDNRFNT 60
MKKKQTVQGTFSKLFGKKHTTTPSTSLYATNPPWIFTQEAPEEGTGGFDGIYYGDNRFNT
Sbjct: 1 MKKKQTVQGTFSKLFGKKHTTTPSTSLYATNPPWIFTQEAPEEGTGGFDGIYYGDNRFNT 60
Query: 61 VSESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNLR 120
VSESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNLR
Sbjct: 61 VSESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNLR 120
Query: 121 LYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEP 180
LYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEP
Sbjct: 121 LYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEP 180
Query: 181 PPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPA 240
PPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPA
Sbjct: 181 PPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPA 240
Query: 241 SPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPR 300
SPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPR
Sbjct: 241 SPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPR 300
Query: 301 SFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEP 360
SFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEP
Sbjct: 301 SFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEP 360
Query: 361 DCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCA 420
DCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCA
Sbjct: 361 DCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCA 420
Query: 421 QKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCG 480
QKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCG
Sbjct: 421 QKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCG 480
Query: 481 SRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTET 540
SRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTET
Sbjct: 481 SRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTET 540
Query: 541 EAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRI 600
EAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRI
Sbjct: 541 EAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRI 600
Query: 601 CENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPA 660
CENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPA
Sbjct: 601 CENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPA 660
Query: 661 TPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKP 720
TPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKP
Sbjct: 661 TPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKP 720
Query: 721 ASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSR 780
ASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSR
Sbjct: 721 ASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSR 780
Query: 781 EVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMA 840
EVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMA
Sbjct: 781 EVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMA 840
Query: 841 LLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPK 900
LLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPK
Sbjct: 841 LLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPK 900
Query: 901 EAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPL 960
EAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPL
Sbjct: 901 EAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPL 960
Query: 961 PKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDL 1020
PKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDL
Sbjct: 961 PKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDL 1020
Query: 1021 RQLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGEPHRGPGLPHG 1080
RQLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGEPHRGPGLPHG
Sbjct: 1021 RQLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGEPHRGPGLPHG 1080
Query: 1081 GTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPGGLHAPRLSLEGAARGAAEAKHKAPGSA 1140
GTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPGGLHAPRLSLEGAARGAAEAKHKAPGSA
Sbjct: 1081 GTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPGGLHAPRLSLEGAARGAAEAKHKAPGSA 1140
Query: 1141 DYGFAPAAGRSPYTTTRYGSPINTFTVRPGTRHPISYVCSGAHRKATS 1188
DYGFAPAAGRSPYTTTRYGSPINTFTVRPGTRHPISYVCSGAHRKATS
Sbjct: 1141 DYGFAPAAGRSPYTTTRYGSPINTFTVRPGTRHPISYVCSGAHRKATS 1188
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 2455 bits (6362), Expect = 0.0
Identities = 1188/1188 (100%), Positives = 1188/1188 (100%)
Query: 1 MKKKQTVQGTFSKLFGKKHTTTPSTSLYATNPPWIFTQEAPEEGTGGFDGIYYGDNRFNT 60
MKKKQTVQGTFSKLFGKKHTTTPSTSLYATNPPWIFTQEAPEEGTGGFDGIYYGDNRFNT
Sbjct: 1 MKKKQTVQGTFSKLFGKKHTTTPSTSLYATNPPWIFTQEAPEEGTGGFDGIYYGDNRFNT 60
Query: 61 VSESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNLR 120
VSESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNLR
Sbjct: 61 VSESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNLR 120
Query: 121 LYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEP 180
LYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEP
Sbjct: 121 LYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEP 180
Query: 181 PPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPA 240
PPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPA
Sbjct: 181 PPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPA 240
Query: 241 SPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPR 300
SPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPR
Sbjct: 241 SPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPR 300
Query: 301 SFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEP 360
SFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEP
Sbjct: 301 SFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEP 360
Query: 361 DCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCA 420
DCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCA
Sbjct: 361 DCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCA 420
Query: 421 QKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCG 480
QKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCG
Sbjct: 421 QKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCG 480
Query: 481 SRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTET 540
SRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTET
Sbjct: 481 SRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTET 540
Query: 541 EAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRI 600
EAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRI
Sbjct: 541 EAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRI 600
Query: 601 CENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPA 660
CENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPA
Sbjct: 601 CENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPA 660
Query: 661 TPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKP 720
TPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKP
Sbjct: 661 TPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKP 720
Query: 721 ASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSR 780
ASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSR
Sbjct: 721 ASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSR 780
Query: 781 EVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMA 840
EVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMA
Sbjct: 781 EVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMA 840
Query: 841 LLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPK 900
LLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPK
Sbjct: 841 LLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPK 900
Query: 901 EAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPL 960
EAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPL
Sbjct: 901 EAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPL 960
Query: 961 PKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDL 1020
PKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDL
Sbjct: 961 PKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDL 1020
Query: 1021 RQLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGEPHRGPGLPHG 1080
RQLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGEPHRGPGLPHG
Sbjct: 1021 RQLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGEPHRGPGLPHG 1080
Query: 1081 GTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPGGLHAPRLSLEGAARGAAEAKHKAPGSA 1140
GTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPGGLHAPRLSLEGAARGAAEAKHKAPGSA
Sbjct: 1081 GTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPGGLHAPRLSLEGAARGAAEAKHKAPGSA 1140
Query: 1141 DYGFAPAAGRSPYTTTRYGSPINTFTVRPGTRHPISYVCSGAHRKATS 1188
DYGFAPAAGRSPYTTTRYGSPINTFTVRPGTRHPISYVCSGAHRKATS
Sbjct: 1141 DYGFAPAAGRSPYTTTRYGSPINTFTVRPGTRHPISYVCSGAHRKATS 1188
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sapiens]
Length = 1188
Score = 2455 bits (6362), Expect = 0.0
Identities = 1188/1188 (100%), Positives = 1188/1188 (100%)
Query: 1 MKKKQTVQGTFSKLFGKKHTTTPSTSLYATNPPWIFTQEAPEEGTGGFDGIYYGDNRFNT 60
MKKKQTVQGTFSKLFGKKHTTTPSTSLYATNPPWIFTQEAPEEGTGGFDGIYYGDNRFNT
Sbjct: 1 MKKKQTVQGTFSKLFGKKHTTTPSTSLYATNPPWIFTQEAPEEGTGGFDGIYYGDNRFNT 60
Query: 61 VSESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNLR 120
VSESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNLR
Sbjct: 61 VSESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNLR 120
Query: 121 LYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEP 180
LYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEP
Sbjct: 121 LYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEP 180
Query: 181 PPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPA 240
PPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPA
Sbjct: 181 PPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPA 240
Query: 241 SPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPR 300
SPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPR
Sbjct: 241 SPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPR 300
Query: 301 SFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEP 360
SFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEP
Sbjct: 301 SFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEP 360
Query: 361 DCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCA 420
DCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCA
Sbjct: 361 DCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCA 420
Query: 421 QKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCG 480
QKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCG
Sbjct: 421 QKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCG 480
Query: 481 SRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTET 540
SRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTET
Sbjct: 481 SRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTET 540
Query: 541 EAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRI 600
EAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRI
Sbjct: 541 EAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRI 600
Query: 601 CENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPA 660
CENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPA
Sbjct: 601 CENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPA 660
Query: 661 TPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKP 720
TPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKP
Sbjct: 661 TPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKP 720
Query: 721 ASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSR 780
ASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSR
Sbjct: 721 ASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSR 780
Query: 781 EVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMA 840
EVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMA
Sbjct: 781 EVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMA 840
Query: 841 LLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPK 900
LLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPK
Sbjct: 841 LLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPK 900
Query: 901 EAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPL 960
EAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPL
Sbjct: 901 EAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPL 960
Query: 961 PKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDL 1020
PKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDL
Sbjct: 961 PKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDL 1020
Query: 1021 RQLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGEPHRGPGLPHG 1080
RQLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGEPHRGPGLPHG
Sbjct: 1021 RQLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGEPHRGPGLPHG 1080
Query: 1081 GTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPGGLHAPRLSLEGAARGAAEAKHKAPGSA 1140
GTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPGGLHAPRLSLEGAARGAAEAKHKAPGSA
Sbjct: 1081 GTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPGGLHAPRLSLEGAARGAAEAKHKAPGSA 1140
Query: 1141 DYGFAPAAGRSPYTTTRYGSPINTFTVRPGTRHPISYVCSGAHRKATS 1188
DYGFAPAAGRSPYTTTRYGSPINTFTVRPGTRHPISYVCSGAHRKATS
Sbjct: 1141 DYGFAPAAGRSPYTTTRYGSPINTFTVRPGTRHPISYVCSGAHRKATS 1188
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 159 bits (403), Expect = 1e-38
Identities = 245/906 (27%), Positives = 307/906 (33%), Gaps = 188/906 (20%)
Query: 139 IPPPPPGPA-PGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEAL 197
+P P GPA P P Q P SP P P + P P AP PP A
Sbjct: 893 LPFPKEGPATPAPKQ---APALSMTSSSPKKARATPAPKGIPASPSPKGAPTPP----AA 945
Query: 198 SPPHTLSSPSIP------TPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFP 251
+PP P+ P TPP PP+P P P P P P SP P
Sbjct: 946 TPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSP 1005
Query: 252 PGGVTKWKSDVALNGRQAEATRASPPRSPAE---PKGSALGPNPEPHLTFPRSFKVPPPT 308
G T T SP SPA PKG++ P P P P T
Sbjct: 1006 KGAPT-----------PPAVTPPSPKGSPAATPFPKGASTPPAATP----PSPKGSPAAT 1050
Query: 309 PVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKA 368
P+ P A P + G + P PP+ P S P P A
Sbjct: 1051 PL-PKGAPTTPAATLPSPKGGPATPSLKGAPTPPA--ATPPSPKGGPATPSPKGAPMPPA 1107
Query: 369 TAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPP--APPLPPAAPPLPCAQKAAHP 426
P SP+ G + TP PP P PPP AP P A PP P A P
Sbjct: 1108 ATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPP 1167
Query: 427 PAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDR 486
P G TP ++ P+ K PSP+ ++
Sbjct: 1168 PKGAPTTPAATPPSPKGGLATPSPKGAPTT------------------------------ 1197
Query: 487 FLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSL 546
P P S +G G P + + PA TPP P+ L S P+
Sbjct: 1198 -------PAATPPSPKG--GLATPSPKGAPTTPAA-TPPS-PKGGLATPSPKGAPTTPAA 1246
Query: 547 TLPS-----VDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRIC 601
T PS P+ +PTP L+ L++ K A PP P+ GG
Sbjct: 1247 TPPSPKGGPATPPPKGAPTPPA-ATPPSLKGGLATPPHKGAPNPAVVTPPSPK--GG--- 1300
Query: 602 ENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKAT-LWPA 660
S P PP +T P S G PP TP PK T PA
Sbjct: 1301 ------PATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPP---SPKGTPTLPA 1351
Query: 661 TPPKATLGPATPLKATSGPTTPLKATS---GPAIASTATTLPTTTSQLMAEKDSGPAGQP 717
T P + GP TP + GPT P S GPA+ T S P G P
Sbjct: 1352 TTPSSKGGPTTP-SSKEGPTPPAATPSHKGGPAM--------TPPSPKRGPAIPSPKGDP 1402
Query: 718 EKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSS 777
PA +S P +A E P++G + PP +P S
Sbjct: 1403 TSPAVIPLS-PKKAPATPVTREGAATPSKGDLT----PPAVTP---------------VS 1442
Query: 778 LSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPA-KPPASAQPTDELLRHPVTGEVVERG 836
L + A P +GG A P K P LPA PP+ +P P +V
Sbjct: 1443 LKKAPATSAP---KGGPATPSS----KGDPTLPAVTPPSPKEP-------PAPKQVATSS 1488
Query: 837 SPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEAS----SDSIFHSQGTPNSF 892
SP +K + A +G +LP + + A+ D I + +
Sbjct: 1489 SP-----------KKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKK 1537
Query: 893 TVVPKLPKEAEKDSPLTTEIPNKWGPRL--GRDAEGTELSRRHNWTKPEPQAPVAWERVA 950
T PKEA +T P K P + ++A T S+ E +P A V
Sbjct: 1538 TPATLAPKEALIPPAMTVPSPKK-TPAIPTPKEAPATPSSK-------EASSPPA---VT 1586
Query: 951 PSNLPQGHPLPKSFSSPP---SPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLG 1007
PS +G P PK PP SPS K E V PP PE P PAP G
Sbjct: 1587 PSTY-KGAPSPKELLIPPAVTSPSPK----EAPTPPAVTPPSPE--KGPATPAPK----G 1635
Query: 1008 RQSSPP 1013
+SPP
Sbjct: 1636 TPTSPP 1641
Score = 133 bits (334), Expect = 1e-30
Identities = 201/794 (25%), Positives = 284/794 (35%), Gaps = 185/794 (23%)
Query: 60 TVSESGTATLKARPRVRP---LLTFLPLNAQENHGLAVPTP-----SVPDDFADKEVTGT 111
T S G T A P L T P A P+P + P A T
Sbjct: 1211 TPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAAT 1270
Query: 112 SSLVNGNLRLYSSVGDLRPGQYGQDLLIPPPPP--GPAPGPPQDISEPPGGSPLPSPPST 169
+ G L G P ++ PP P GPA PP+ PP +P PSP +
Sbjct: 1271 PPSLKGGLATPPHKGAPNPA------VVTPPSPKGGPATSPPKGAPTPPAATP-PSPKGS 1323
Query: 170 APPPPPLLLEPPPPPSMAPPPP---PVLEALSP-----PHTLSSPSIPTPPDFIPPAPPL 221
PPP P PP++ PP P P L A +P P T SS PTPP P
Sbjct: 1324 PGTPPP--KGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGG 1381
Query: 222 AFLAPPPP------PVPAPAPPAPA--------SPHTVGTRLFPPGGVTKWKSDVALNGR 267
+ PP P P P P +PA +P T TR G T K D+
Sbjct: 1382 PAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTR---EGAATPSKGDLTPPAV 1438
Query: 268 QAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKE 327
+ + +P S PKG P+ + T P V PP+P +E P +
Sbjct: 1439 TPVSLKKAPATS--APKGGPATPSSKGDPTLP---AVTPPSP-----------KEPPAPK 1482
Query: 328 EGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPA--SPRLGQSQSQADE 385
+ AT +P + P P+ P A P P E+ AT + P + + +
Sbjct: 1483 QVATSSSPKKAPATPAPMGAPTLP-----AVIPSSPKEVPATPSSRRDPIAPTATLLSKK 1537
Query: 386 RAGTPPPAPPLPPPAPPLP----PPAPPLPPAAPPLPCAQKAAHPPAGFTKT-------- 433
T P L PPA +P PA P P AP P +++A+ PPA T
Sbjct: 1538 TPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPK 1597
Query: 434 -----PKSSSPALKPKPNP--------------PSPENTASSAPVDWRDPSQMEKLRNEL 474
P +SP+ K P P P+P+ T +S PV PS ++
Sbjct: 1598 ELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPV---TPSSLKDSPTSP 1654
Query: 475 AAYLCGSRREDRFLSHRPGPTVAPQSKEG---KKGPRLPEKETLLSLPAKDTPPGVPEKS 531
A+ C + G TV PQ+ +G KKGP KE L++ PA ++ P + +
Sbjct: 1655 ASVTC-----------KMGATV-PQASKGLPAKKGP-TALKEVLVA-PAPESTPIITAPT 1700
Query: 532 LGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPP 591
G ++ A P P PS A+ +K + ++ P
Sbjct: 1701 RKGPQTKKSSATS----------PPICPDPS---------------AKNGSKGPLSTVAP 1735
Query: 592 KPRLEGGRICENGA-DDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGP----------- 639
P L + A D P PP+S P T+ + +L
Sbjct: 1736 APLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPS 1795
Query: 640 ---AIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSG----PTTPLKATSGPA-I 691
++P +P P +PPK P++P P+ PL P P + SG
Sbjct: 1796 PPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGGVPF 1855
Query: 692 ASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPS------------E 739
S +PT S AG P S + +G G+ S +
Sbjct: 1856 QSVLVNMPTPKS----------AGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQD 1905
Query: 740 ATRLPTQGARSSAA 753
+T+ TQ A+ +AA
Sbjct: 1906 STQATTQQAQLAAA 1919
Score = 130 bits (328), Expect = 6e-30
Identities = 192/723 (26%), Positives = 250/723 (34%), Gaps = 119/723 (16%)
Query: 138 LIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPP---PVL 194
L PPP G P P GG PSP P P P P +A P P P
Sbjct: 1163 LATPPPKGAPTTPAATPPSPKGGLATPSPKGA--PTTPAATPPSPKGGLATPSPKGAPTT 1220
Query: 195 EALSPPHT---LSSPS---IPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTR 248
A +PP L++PS PT P PP+P PPP AP PPA P G
Sbjct: 1221 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG--PATPPPKGAPTPPAATPPSLKGGL 1278
Query: 249 LFPP-GGVTKWKSDVALNGRQAEATRASPPR--------SPAEPKGSALGPNPEPHLTFP 299
PP G + + AT SPP+ +P PKGS P P+ T P
Sbjct: 1279 ATPPHKGAPNPAVVTPPSPKGGPAT--SPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPP 1336
Query: 300 RSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPE 359
V PP+P T ++P P + G T + P PP A
Sbjct: 1337 ---AVTPPSPKGTPTLPA----TTPSSKGGPTTPSSKEGPTPP--------------AAT 1375
Query: 360 PDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPC 419
P G A P SP+ G PA P P P P P P AP P
Sbjct: 1376 PSHKGG-PAMTPPSPKRG--------------PAIPSPKGDPTSPAVIPLSPKKAPATPV 1420
Query: 420 AQKAAHPPAGFTKTPKSSSP-ALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYL 478
++ A P+ TP + +P +LK P +P+ + P DP+ L A
Sbjct: 1421 TREGAATPSKGDLTPPAVTPVSLKKAPATSAPKG-GPATPSSKGDPT--------LPAVT 1471
Query: 479 CGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPA------KDTP--PGVPEK 530
S +E P P S KK P P +LPA K+ P P
Sbjct: 1472 PPSPKEP------PAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRD 1525
Query: 531 SLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLP 590
+ ++ ++ P+ P IP PS ++ + + E A PS
Sbjct: 1526 PIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKK-----TPAIPTPKEAPATPSSKEAS 1580
Query: 591 PKPRLEGGRICENGADDDK-LSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIP-PKATP- 647
P + GA K L P A P P P GPA P PK TP
Sbjct: 1581 SPPAVTPSTY--KGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPT 1638
Query: 648 -EPAIPPKATLWPATPPKAT--LGPATP-----LKATSGPTTPLKATSGPAIASTATTLP 699
P P P +P T +G P L A GPT + PA P
Sbjct: 1639 SPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPA--------P 1690
Query: 700 TTTSQLMAEKDSGPAGQPEKPASQEV-STPSQARGEGSP----SEATRLPTQ--GARSSA 752
+T + A GP + S + PS G P + A LP Q ++++
Sbjct: 1691 ESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAK 1750
Query: 753 AFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVK-EPPGLPA 811
SP G P K ++ + E + P A AA P PV + P +P
Sbjct: 1751 GKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAA-PSPPVSLPLAPSPVPT 1809
Query: 812 KPP 814
PP
Sbjct: 1810 LPP 1812
Score = 120 bits (302), Expect = 6e-27
Identities = 186/735 (25%), Positives = 253/735 (34%), Gaps = 116/735 (15%)
Query: 138 LIPPPPPGPAPGPPQDISEPPGGSPLPSP---PST--APPPPPLLLEPPPPPSMAPPP-- 190
L P P G P P GG PSP P+T A PP P PPP AP P
Sbjct: 1209 LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPA 1268
Query: 191 --PPVLEA--LSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPH-TV 245
PP L+ +PPH P P PP+P PP P P P SP +
Sbjct: 1269 ATPPSLKGGLATPPH----KGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSP 1324
Query: 246 GTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVP 305
GT PP G + + + A+ P S P + P P P P
Sbjct: 1325 GTP--PPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGP 1382
Query: 306 ---PPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDC 362
PP+P R +IP + + +P + P P A+ D P
Sbjct: 1383 AMTPPSPKRGPAIP---SPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVT 1439
Query: 363 PGEL-KATAPASPRLGQSQSQADERAGTPPPAPPLP--PPAP--------PLPPPAPPLP 411
P L KA A ++P+ G + + P PP P PPAP P PA P P
Sbjct: 1440 PVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAP 1499
Query: 412 PAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLR 471
AP LP ++ P TP S + P S + A+ AP + P M
Sbjct: 1500 MGAPTLPAVIPSS--PKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTV-- 1555
Query: 472 NELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKS 531
P P P K+ P P S A P P
Sbjct: 1556 --------------------PSPKKTPAIPTPKEAPATPS-----SKEASSPPAVTPSTY 1590
Query: 532 LGGSSLTETEAAPSLTLPSVDYIPQDSPT-PSVRQIRNELEARLSSAAEKEAKPSI--GS 588
G S E P++T PS P+++PT P+V E + P + S
Sbjct: 1591 KGAPSPKELLIPPAVTSPS----PKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSS 1646
Query: 589 LPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPE 648
L P C+ GA + SK + P T+L+ + ++ PA P++TP
Sbjct: 1647 LKDSPTSPASVTCKMGATVPQASKGLPAKKGP--------TALK-EVLVAPA--PESTPI 1695
Query: 649 PAIP----PKATLWPATPPKATLGPATPLKATSGPTTPLKATS-GPAIASTATTLPTTTS 703
P P+ AT P P+ A +G PL + P + + T
Sbjct: 1696 ITAPTRKGPQTKKSSATSPPICPDPS----AKNGSKGPLSTVAPAPLLPVQKDSSKTAKG 1751
Query: 704 QLMAEKDSGPAGQPEKPASQEVST---------PSQARGEGSPSEATRLPTQGARSSAAF 754
+ + GP PE AS ++ P A +PS LP
Sbjct: 1752 KDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPL-APSPVPTL 1810
Query: 755 PPK-----TSPG-GGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEP-- 806
PPK +SPG E P + L + ++ P GG P + V V P
Sbjct: 1811 PPKQQFLPSSPGLVLESPSKPLAPADEDEL---LPLIPPEPISGGV--PFQSVLVNMPTP 1865
Query: 807 --PGLPAKPPASAQP 819
G+P P++ QP
Sbjct: 1866 KSAGIPVPTPSAKQP 1880
Score = 107 bits (266), Expect = 9e-23
Identities = 260/1056 (24%), Positives = 349/1056 (33%), Gaps = 190/1056 (17%)
Query: 165 SPPSTAPPPPPLLLEPPPPPSMAP--PPPPVLEALSPPHTLSSPSIPTPPDF--IPPAPP 220
SPP ++ P + P MAP P P + + SP +P P D +P +
Sbjct: 464 SPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVL 523
Query: 221 LAFLAPPP-PPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASP--P 277
+ F VPA AP SP G V N ++T +SP P
Sbjct: 524 VKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIP 583
Query: 278 RSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSR 337
SP P P + P TS + V + + + A +
Sbjct: 584 LSPEATLAKKSLGEPLP---------IGKPASSMTSPLGVNSSASVIKTDSYAGPDSAG- 633
Query: 338 LPLPPSFHIRPASQVYPDRAPEP------DCPGELKATAPASPRLGQSQSQADE----RA 387
PL S I P +P + +P G T ASP L + S A + +
Sbjct: 634 -PLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKE 692
Query: 388 GTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKS-SSPALKPKPN 446
GT P L P A P AP +P CA A A + PKS SP+L P
Sbjct: 693 GTLTTLP-LVPTASENCPVAP-----SPQNTCAPLATLVLA--PEIPKSVPSPSLPPAGT 744
Query: 447 PPSPE------NTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGP------ 494
PP + +T++ APV P + + A+ S+ +L+ P P
Sbjct: 745 PPGTKKVDGISHTSALAPVA-SSPKECPT-EDSGASATASSKGTLTYLADSPSPLGVSVS 802
Query: 495 --TVAPQSKEGKKGPRLPEKETLLSLPAKDTPPG-VPEKSLGGSSLTETEAAPSLTLPSV 551
T P +K+G GP P LS P +PE SL S ++ +P+ T
Sbjct: 803 PQTKRPPTKKGSAGPDTPIGN--LSSPVSPVEASFLPENSL---SFQGSKDSPATTHSPT 857
Query: 552 DYIPQDSPTPSVRQIRNELEARLSSAAEKEAK-PSIGSLP-PKPRLEGGRICENGADDDK 609
P+ +PTPS L + + KE PS+ +LP PK EG
Sbjct: 858 PPSPKGAPTPSAV---TPLSPKGVTLPPKETPTPSVVNLPFPK---EGP----------- 900
Query: 610 LSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPA-TPPKATLG 668
A P Q+ L T+S KA PA PK P P A PA TPP G
Sbjct: 901 -----ATPAPKQAPALSMTSSSPKKARATPA--PKGIPASPSPKGAPTPPAATPPSPKGG 953
Query: 669 PATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTP 728
PATP + TP AT AT P A P G P P+ + TP
Sbjct: 954 PATP--SPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTP 1011
Query: 729 ---SQARGEGSPSEATRLPTQGARSSAAFPP--KTSPGGGEVPCLYKPHCHQSSLSREVA 783
+ +GSP+ AT P + AA PP K SP +P A
Sbjct: 1012 PAVTPPSPKGSPA-ATPFPKGASTPPAATPPSPKGSPAATPLP---------KGAPTTPA 1061
Query: 784 VVMPTLARGGAAGP---GEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMA 840
+P+ +GG A P G P P P PA+ P +G+PM
Sbjct: 1062 ATLPS-PKGGPATPSLKGAPTPPAATPPSPKGGPATPSP---------------KGAPMP 1105
Query: 841 LLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPK 900
A + G + G + P + A+ +G P + P PK
Sbjct: 1106 PA-ATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPP----KGAPTTPAATPPSPK 1160
Query: 901 EAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPL 960
L T P K P T S + P P+ AP+ P
Sbjct: 1161 GG-----LATP-PPKGAPTT---PAATPPSPKGGLATPSPKG-------APTTPAATPPS 1204
Query: 961 PKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDL 1020
PK + PSP PP P+ P+P ++PP
Sbjct: 1205 PKGGLATPSPKGAPTTPA------ATPPSPK--GGLATPSPKGAPTTPAATPPS------ 1250
Query: 1021 RQLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGEPHRG------ 1074
P GP PP G PA + GGL PH+G
Sbjct: 1251 ---PKGGPATPPPKGAPTPPAATPPSLKGGL----------------ATPPHKGAPNPAV 1291
Query: 1075 --PGLPHGGTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPGGLHAPRLSLEGAARGAAEA 1132
P P GG + S P P S G PP G P + +G
Sbjct: 1292 VTPPSPKGGP--ATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTL 1349
Query: 1133 KHKAPGSADYGFAPAAGRSP----YTTTRYGSPINT 1164
P S P++ P T + G P T
Sbjct: 1350 PATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMT 1385
Score = 97.8 bits (242), Expect = 5e-20
Identities = 229/1014 (22%), Positives = 332/1014 (32%), Gaps = 177/1014 (17%)
Query: 192 PVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPV-PAPAPPAPASPHTVGTRLF 250
P ++ +S H+ + S P+ IPP P + P P AP P T+ +
Sbjct: 334 PTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITC 393
Query: 251 PPGGVTKWKSDVALNGRQAEATRASPPRS-----PAEPKGSALGPNP-----------EP 294
P G + +L+ + ++SP + A+ S++G P P
Sbjct: 394 SPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAP 453
Query: 295 HLTFPRSFKVPPP------------TPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPP 342
TF + V PP +P PV A + P + T + P PLP
Sbjct: 454 TTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPV--APKEPSTQVATTLRIPVSPPLPD 511
Query: 343 SFHIR--PASQV--YPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPP 398
++ P+S + +P + P L+ AP SP +QA P PL
Sbjct: 512 PEDLKNLPSSVLVKFPTQKDLQTVPASLEG-APFSP------AQAGLTTKKDPTVLPLVQ 564
Query: 399 PAPPLPPP-----APPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENT 453
AP P + P P +P A+K+ P P KP + SP
Sbjct: 565 AAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPL----------PIGKPASSMTSPLGV 614
Query: 454 ASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPT-VAPQSKEGKKG---PRL 509
SSA V D L + F P VAP + +G
Sbjct: 615 NSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTAS 674
Query: 510 PEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNE 569
P E +SL K+ P V E +L L T + PS PQ++ P +
Sbjct: 675 PFLEGTVSLAPKNHP--VKEGTLTTLPLVPTASENCPVAPS----PQNTCAPLATLV--- 725
Query: 570 LEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTT 629
L + + + P G+ P +++G I A S P K P + + T
Sbjct: 726 LAPEIPKSVPSPSLPPAGTPPGTKKVDG--ISHTSALAPVASSP--KECPTEDSGASATA 781
Query: 630 SLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGP 689
S + G +P P L + P+ P K ++GP TP+ S P
Sbjct: 782 SSK-----GTLTYLADSPSP-------LGVSVSPQTKRPPTK--KGSAGPDTPIGNLSSP 827
Query: 690 AIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGAR 749
A+ LP + KDS PA+ TP +G +PS T L +G
Sbjct: 828 VSPVEASFLPENSLSFQGSKDS--------PATTHSPTPPSPKGAPTPSAVTPLSPKG-- 877
Query: 750 SSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGL 809
PPK +P V + + ++ + T ++ P + P G+
Sbjct: 878 --VTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMT-----SSSPKKARATPAPKGI 930
Query: 810 PAKPPASAQPTDELLRHPVTGEVVERGSP--MALLLAARQRAQKGRSVGAALGRSSLPGS 867
PA P PT P SP AA + KG + + P +
Sbjct: 931 PASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPA 990
Query: 868 LRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGT 927
S + ++ S +G P V P P K SP T P +G
Sbjct: 991 ATPPSPKGGPATPS---PKGAPTPPAVTPPSP----KGSPAATPFP-----------KGA 1032
Query: 928 ELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPS---PSNKREEEEEEFNFE 984
T P P +P P PLPK + P+ PS K
Sbjct: 1033 S-------TPPAATPP------SPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGA 1079
Query: 985 VIPP---PPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPALGFSRFPA 1041
PP PP P P+P + ++PP P G PP G PA
Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPAATPPS---------PKGGLATPPHKGAPTTPA 1130
Query: 1042 GARYAGAGGLERFSGGGRSLIKKRLYVGEPHRGPGLPHGGTGRSLSSPNCFGPQPGGPEM 1101
+ GGL G P P P GG L++P P G P
Sbjct: 1131 ATPPSPKGGLATPPPKGAPT--------TPAATPPSPKGG----LATP----PPKGAPTT 1174
Query: 1102 RRVNSAGRAPPGGLHAPRLSLEGAARGAAEAKHKAPGSADYGFAPAAGRSPYTT 1155
+P GGL P + +GA P S G A + + TT
Sbjct: 1175 PAATPP--SPKGGLATP------SPKGAPTTPAATPPSPKGGLATPSPKGAPTT 1220
Score = 82.8 bits (203), Expect = 2e-15
Identities = 262/1131 (23%), Positives = 369/1131 (32%), Gaps = 144/1131 (12%)
Query: 131 GQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPP 190
GQ G L PPP PAP +S SP PSP + A P LE P P S +
Sbjct: 39 GQPGPTL---PPPCSPAP-QQCPLSAANQASPFPSPSTIASTP----LEVPFPQSSSGTA 90
Query: 191 PPVLEALSPPHTLSSPSIPTPPDFIPPA------PPLAFLAPPPPPVPAPAPPAPASPHT 244
P+ A P L P++ PP I PA P +A P AP +PH+
Sbjct: 91 LPLGTAPEAPTFL--PNLIGPP--ISPAALALASPMIAPTLKGTPSSSAPLALVALAPHS 146
Query: 245 V-GTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFK 303
V + FPP +T S VA+ S P +P+EPK + N P P
Sbjct: 147 VQKSSAFPPNLLTSPPS-VAV-AESGSVITLSAPIAPSEPKTNL---NKVPSEVVPNPKG 201
Query: 304 VPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRA-----P 358
P P P S++P + G S P+ + AS D
Sbjct: 202 TPSP-PCIVSTVPYHCVTPMASIQSGVA----SLPQTTPTTTLAIASPQVKDTTISSVLI 256
Query: 359 EPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLP 418
P PG L P SP S S + P A P PP P+ + P
Sbjct: 257 SPQNPGSLSLKGPVSPPAALSLS-----TQSLPVVTSSQKTAGPNTPPDFPISLGSHLAP 311
Query: 419 CAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAP----VDWRDPSQMEKLRNEL 474
Q + +T S+ K +T +S P V PS+ E + +
Sbjct: 312 LHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATV 371
Query: 475 AAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPG-------- 526
AA+ + D+ S T +P T SL K +P
Sbjct: 372 AAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTT--SLILKSSPNATYHYPLVA 429
Query: 527 -VPEKSLGGSSLTETE-----AAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSA--A 578
+P S+G + L T AAP+ T + + + I A L A A
Sbjct: 430 QMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVA 489
Query: 579 EKEAKPSIGS---LPPKPRLEGGRICENGADDDKLSKPVAKNLP--PQSTTLLP------ 627
KE + + +P P L +N + P K+L P S P
Sbjct: 490 PKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQA 549
Query: 628 --TTSLQPKAMLGPAIPPKATP---EPAIPPKATLWP-ATPPKATLGPATPL-KATSGPT 680
TT P + PK +P + P+ L P AT K +LG P+ K S T
Sbjct: 550 GLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMT 609
Query: 681 TPLKATSGPAIASTATTL-PTTTSQLMAEKDSGP--AGQPEKPASQEVSTPSQARGEGSP 737
+PL S ++ T + P + L+ P A P + A P+ A+G
Sbjct: 610 SPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKG---T 666
Query: 738 SEATRLPTQGARSSAAFPPKTSP-GGGEVPCL-----YKPHCHQSSLSREVAVVMPTLAR 791
S T + + + PK P G + L +C + + + TL
Sbjct: 667 STYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATL-- 724
Query: 792 GGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVE--RGSPMALLLAARQRA 849
P P V P PA P + D + V + P A+ +
Sbjct: 725 --VLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATAS 782
Query: 850 QKGRSVGAA-----LGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPK---- 900
KG A LG S P + R + + A D+ + +P S LP+
Sbjct: 783 SKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLS 842
Query: 901 -EAEKDSPLTTEIPNKWGPR--------LGRDAEGTELSRRHNWTKPEPQAPVAWERVAP 951
+ KDSP TT P P+ +G L + T P E A
Sbjct: 843 FQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPAT 902
Query: 952 SNLPQGHPLPKSFSSP----PSPSNKREEEEEEFNFEVIPP---PPEFSNDPEPPAPALQ 1004
Q L + SSP +P+ K PP PP P P+P
Sbjct: 903 PAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWA 962
Query: 1005 YLGRQSSPPRNNYSDLRQLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGR---SL 1061
++PP P GP P G PA + GG S G
Sbjct: 963 PTPPAATPPS---------PKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPA 1013
Query: 1062 IKKRLYVGEPHRGPGLPHGGTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPGGLHAPRLS 1121
+ G P P P G + ++P P P G +A P G P +
Sbjct: 1014 VTPPSPKGSPAATP-FPKGASTPPAATP----PSPKGSP-----AATPLPKGAPTTPAAT 1063
Query: 1122 LEGAARGAAEAKHKAPGSADYGFAPAAGRSPYTTTRYGSPINTFTVRPGTR 1172
L G A K + P+ P T + G+P+ P +
Sbjct: 1064 LPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPK 1114
Score = 57.4 bits (137), Expect = 8e-08
Identities = 204/948 (21%), Positives = 304/948 (32%), Gaps = 201/948 (21%)
Query: 167 PSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAP 226
P A P + P P P+ ALS L P PT P PAP L+
Sbjct: 2 PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPG-PTLPPPCSPAPQQCPLSA 60
Query: 227 PPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGS 286
P P+P AS T L P + + + L G EA P +
Sbjct: 61 ANQASPFPSPSTIAS-----TPLEVPFPQSSSGTALPL-GTAPEAPTFLP---------N 105
Query: 287 ALGPNPEP-HLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFH 345
+GP P L P +SS P+ AP + ++ P+ L PPS
Sbjct: 106 LIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVA 165
Query: 346 IRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPP 405
+ + V AP AP+ P+ ++ P+ +P P
Sbjct: 166 VAESGSVITLSAP----------IAPSEPKTNLNK----------VPSEVVPNPK---GT 202
Query: 406 PAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPS 465
P+PP + P C A +G P+++ +P + T SS + ++P
Sbjct: 203 PSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPG 262
Query: 466 QMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPP 525
+ L+ ++ S LS + P V K GP P + +SL + P
Sbjct: 263 SL-SLKGPVSPPAALS------LSTQSLPVVTSSQKTA--GPNTP-PDFPISLGSHLAP- 311
Query: 526 GVPEKSLGGSSLTETEAAPSLTLP-----SVDYIPQDSPTPSVRQIRNELEAR-----LS 575
+ + S G L +L+ P SVD+ + PS R + L +R +
Sbjct: 312 -LHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPAT 370
Query: 576 SAAEKEAKPSIGSLP---------PKPRLEGGRICENGADDDKLSK---------PVAKN 617
AA PS+ P P L + K P+
Sbjct: 371 VAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQ 430
Query: 618 LP-------------PQSTTLLPTTSLQPKAMLGPAIP--PKATPEPAIPPKATLWPATP 662
+P P + PTT+ + + P + P + EP P + P P
Sbjct: 431 MPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAP 490
Query: 663 PKATLGPATPLKATSGPTTP----LK-------------------------ATSGPAIAS 693
+ + AT L+ P P LK A PA A
Sbjct: 491 KEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAG 550
Query: 694 TATTL-PTTTSQLMAEKDSGPAGQ-----PEKPASQEVSTPSQARGE----GSPSEATRL 743
T PT + A + P+ Q PE P S E + ++ GE G P+ +
Sbjct: 551 LTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTS 610
Query: 744 PTQGARSSAAFPPKTSPGGGE------VPCLYKPHCHQSSL-SREVAVVMPTLARG---- 792
P G SSA+ S G + L P L S + A V PT A+G
Sbjct: 611 PL-GVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTY 669
Query: 793 ------------GAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMA 840
A PV+ LP P AS PV +P+A
Sbjct: 670 TTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASE-------NCPVAPSPQNTCAPLA 722
Query: 841 LLLAARQRAQKGRS-----VGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVV 895
L+ A + + S G G + G + ASS ++ + S T
Sbjct: 723 TLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATAS 782
Query: 896 PK--LPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSN 953
K L A+ SPL + P+ + P + A +
Sbjct: 783 SKGTLTYLADSPSPLGVSV------------------------SPQTKRPPTKKGSAGPD 818
Query: 954 LPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAP 1001
P G + SSP SP E +F+ P ++ P PP+P
Sbjct: 819 TPIG-----NLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSP 861
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 154 bits (388), Expect = 6e-37
Identities = 229/808 (28%), Positives = 302/808 (37%), Gaps = 156/808 (19%)
Query: 139 IPPPPPGPAPGPPQDISEPPGGSPLP-SPPSTAPPPPPLLLEPPP-------PPSMAPPP 190
+PPP P P PP +PLP +PPS + PP L PP PPSM PP
Sbjct: 317 VPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPP 376
Query: 191 ---PPVLEALSP---PHTLSSPSIPTPP-----------------------DFIPPAPPL 221
PP L+ + P PH+L+SPS+ PP F+ +P
Sbjct: 377 MQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQ 436
Query: 222 AFLAPPPPPVPAPAPP----------APASPHTVGTRLFPPGGVTKWKSDVALNGRQAEA 271
+ P PA PP PASP + T L P V+ S + ++ QA +
Sbjct: 437 TQASLTSPSRPASTPPDSPPLQAPLSLPASP-PLQTSLSP--AVSPLSSPLTIHPLQALS 493
Query: 272 TRASPPRSPAEPKGSALGPNPE-------PHL-TFPRSFKVPP--------PTPVRTSSI 315
+ AS SP P S + P E P L T P S PP P P++T+S
Sbjct: 494 SLAS--HSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASA 551
Query: 316 PVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAP---- 371
P+ P E AP L PPS P P P+ P + P
Sbjct: 552 PL----TTPHLETPPC-PAPCPLQAPPS----------PLTTPPPETPSSIATPPPQAPP 596
Query: 372 --ASPRLGQSQSQADERAGTPPP-APP---LPP-PAPPLPPPAPPLPPAAPPLPCAQKA- 423
ASP L S TPPP APP LPP APP PP +PPL P A P P A A
Sbjct: 597 ALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNAL 656
Query: 424 AHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRR 483
A +P S P P P SP + S+ P PS LAA
Sbjct: 657 AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS--------LAA------- 701
Query: 484 EDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAA 543
L P P +P P P+ L+ P PP P S T
Sbjct: 702 --PPLQVPPSPPASPPMSPSATPP--PQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRV 757
Query: 544 PSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICEN 603
P L +P P+P + L A A P + +LP P G+ +
Sbjct: 758 PPLLAAPPLQVP---PSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS 814
Query: 604 GADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPP 663
+ +S P+A PPQ+ +L LQ +PP P + +A P TP
Sbjct: 815 PSASLPMS-PLA-TPPPQAPPVLAAPLLQ--------VPPSPPASPTL--QAPRRPPTPG 862
Query: 664 KAT--LGPATPLKATSGP-----TTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAG- 715
T GP L GP +P SGP +A +++ +T +L DSGP G
Sbjct: 863 PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRG-YDSGPEGG 921
Query: 716 -QPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSS-AAFPPKTSPGGGEVPC-LYKPH 772
P E++ A P A L +GA + +PP T PG + C +Y+
Sbjct: 922 AAASPPPDAELAACHPAAWSRGP--APPLAFRGAPGAPLPWPPATGPGSADGLCTIYETE 979
Query: 773 CHQSSLSREVAV---VMPTLARG-GAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPV 828
+S+ A+ P + G AAG G G ++ P A+ EL +
Sbjct: 980 GPESATPAPGALDPGPSPGTSGGKAAAGAG--------AGASSRSPKQAR-LGELPLGAL 1030
Query: 829 TGEVVERGSPMALLLAARQRAQKGRSVG 856
VV+ LLLAA + A G G
Sbjct: 1031 QASVVQHLLSRTLLLAAAEGAAGGSGGG 1058
Score = 124 bits (310), Expect = 7e-28
Identities = 190/758 (25%), Positives = 266/758 (35%), Gaps = 136/758 (17%)
Query: 158 PGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDF--- 214
P P P+ P P L+ PP + PP AL P LSS + TP
Sbjct: 257 PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP---LSSSPLATPSPSGTK 313
Query: 215 ---IPP----APPLAFLAPPPPPVPAP---APPAPASPHTVGTRLFPPGGVTKWKSDVAL 264
+PP A PL PP PP+ P APP+P++P ++ T PP A
Sbjct: 314 ARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPP----------AT 363
Query: 265 NGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAP 324
QA + +PP A P + P PH S + PP+P+ SS+ + +P
Sbjct: 364 PPSQAPPSMTTPPMQ-APPSLQTIPPIQVPHSLTSPSLQA-PPSPLALSSLQATTSLGSP 421
Query: 325 RKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQAD 384
+ AT + P + S+ P P P + + PASP L S S A
Sbjct: 422 TLQ--ATHSFLTMSPRQTQASLTSPSR--PASTPPDSPPLQAPLSLPASPPLQTSLSPAV 477
Query: 385 ERAGTPPPAPPL---------PPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPK 435
+P PL P AP PPL + P + + PPA T P
Sbjct: 478 SPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQT--PPASLTTPPL 535
Query: 436 SSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPT 495
+ P+L P P TAS+ P L C L P P
Sbjct: 536 ENLPSL-----APPPLQTASA-------PLTTPHLETPPCPAPCP-------LQAPPSPL 576
Query: 496 VAPQSKEGKKGPRLPEKETLLSLPAKDTPP--------GVPEKSLGGSSLTETEAAPSLT 547
P PE + ++ P PP G+P L + +A P L
Sbjct: 577 TTPP----------PETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLA 626
Query: 548 LPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADD 607
LP + P +P + + + +A + S PP P ++
Sbjct: 627 LPPLQAPPSPPASPPLSPLATP-SPQAPNALAVHLLQAPFSPPPSPPVQA---------- 675
Query: 608 DKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGP-AIPPKATPEPAIPPKATLWPATPPKAT 666
S P + PP S + P + P P +PP P + P AT P PP
Sbjct: 676 -PFSPPAS---PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA 731
Query: 667 LGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVS 726
A PL+ P + P ++ +AT P L A P P PAS +S
Sbjct: 732 ---APPLQVPPSP------PASPPMSPSATPPPRVPPLLAAPPLQVP---PSPPASLPMS 779
Query: 727 TPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVM 786
++ + P+ AT P Q S PP + PG Q+ S ++ M
Sbjct: 780 PLAKPPPQAPPALATP-PLQALPS----PPASFPG-------------QAPFSPSASLPM 821
Query: 787 PTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVT--GEVVERGSPMALLLA 844
LA P PV +P PPAS PT + R P T + G + L LA
Sbjct: 822 SPLATPPPQAP--PVLAAPLLQVPPSPPAS--PTLQAPRRPPTPGPDTSVSGPRLTLALA 877
Query: 845 ARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSI 882
RS + L L G HS A ++ + +
Sbjct: 878 PGPPPPPSRSPSSTLSGPDLAG----HSSSATSTPEEL 911
Score = 119 bits (298), Expect = 2e-26
Identities = 277/1177 (23%), Positives = 374/1177 (31%), Gaps = 259/1177 (22%)
Query: 130 PGQYGQDLLIPPPPPGPAPGPP-----------------QDISEPPGGSPLPSPPSTAPP 172
P LL P PP P P PP + ++E GG + P +AP
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 173 PPPL----------LLEPP-------PPPSMAPPPPPVLEALSPPHTLSSPSIPTP---- 211
P PP PP+ P PV S P S + P P
Sbjct: 77 AGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPV----SSPGRASGTTRPGPLGQK 132
Query: 212 --------------PDFIPPAPPLAFLAPPPPPVPAPAPPAPA---SPHTVGTRLFPPGG 254
P L+ A P P P+PA GT + P
Sbjct: 133 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP 192
Query: 255 VTKWKSDVALNGRQAEATRAS-----PPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTP 309
+ G + + AS P A + SA G P S P +P
Sbjct: 193 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 252
Query: 310 VRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKAT 369
R+ A+ PR ++ P L +RP QV P R G L ++
Sbjct: 253 ARSG----PSARGTPRAPAHPSQPKPKGLQA-----LRP-PQVTPPRKDAAPALGPLSSS 302
Query: 370 APASPRLGQSQSQ---ADERAGTPPPA--PPLPPPAPPLP--PPAPPLPPAAP--PLPCA 420
A+P ++++ + A TP PA PP PP A PLP PP+P PP+ P P A
Sbjct: 303 PLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPA 362
Query: 421 QKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCG 480
+ P T P + P+L+ P P + S + P + L+ +
Sbjct: 363 TPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPT 422
Query: 481 SRREDRFLSHRPGPTVA---PQSKEGKKGPRLPEKETLLSLPAK-----DTPPGV----- 527
+ FL+ P T A S+ P P + LSLPA P V
Sbjct: 423 LQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSS 482
Query: 528 -----------------PEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNEL 570
P+ L + E SL PS+ P TP + + +
Sbjct: 483 PLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLA 542
Query: 571 EARLSSAAEKEAKPSIGSLP-PKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTT 629
L +A+ P + + P P P C A L+ P PP++ + + T
Sbjct: 543 PPPLQTASAPLTTPHLETPPCPAP-------CPLQAPPSPLTTP-----PPETPSSIATP 590
Query: 630 SLQ-PKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSG 688
Q P A+ P P + P P + P AT P PP L PL+A P +
Sbjct: 591 PPQAPPALASP--PLQGLPSPPLSPLATPPPQAPPXLAL---PPLQAPPSP------PAS 639
Query: 689 PAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGA 748
P ++ AT P + L P P P Q +P P
Sbjct: 640 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP---------------PASPP 684
Query: 749 RSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPG 808
S +A PP +P P L P +S + P A A P P++V PP
Sbjct: 685 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP--PLQV--PPS 740
Query: 809 LPAKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSL---- 864
PA PP S T P L A Q S A+L S L
Sbjct: 741 PPASPPMSPSATP---------------PPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP 785
Query: 865 ---PGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLG 921
P +L QA S + F Q P P + SPL T
Sbjct: 786 PQAPPALATPPLQALPSPPASFPGQ--------APFSPSASLPMSPLAT----------- 826
Query: 922 RDAEGTELSRRHNWTKPEPQAPVAWE----RVAPSNLPQGHPLPKSFSSPPSPSNKREEE 977
P PQAP +V PS P P ++ PP+P
Sbjct: 827 ----------------PPPQAPPVLAAPLLQVPPS--PPASPTLQAPRRPPTPGPDTSVS 868
Query: 978 EEEFNFEVIP-PPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLRQL---PNAGPGAPP- 1032
+ P PPP S P G SS + +LR P G A P
Sbjct: 869 GPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS-ATSTPEELRGYDSGPEGGAAASPP 927
Query: 1033 ---------ALGFSRFPA-GARYAGAGGL----ERFSGGGRSLIKKRLYVGE------PH 1072
+SR PA + GA G +G G + +Y E P
Sbjct: 928 PDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPA 987
Query: 1073 RG---PGLPHGGTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPGGLHA-------PRLSL 1122
G PG G +G ++ G P+ R+ G P G L A R L
Sbjct: 988 PGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARL---GELPLGALQASVVQHLLSRTLL 1044
Query: 1123 EGAARGAAEAKHKAPGSADYGFAPAAGRSPYTTTRYG 1159
AA GAA PG A+ G R+ + G
Sbjct: 1045 LAAAEGAAGGSGGGPGGAEGGGVTGGARAALSDAELG 1081
Score = 117 bits (293), Expect = 7e-26
Identities = 147/497 (29%), Positives = 188/497 (37%), Gaps = 86/497 (17%)
Query: 73 PRVRPL---LTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNLRLYSSVGDLR 129
P V PL LT PL A + LA +P P SSL+ L SS+
Sbjct: 475 PAVSPLSSPLTIHPLQALSS--LASHSPQAP----------LSSLIMPPLETQSSLAPPS 522
Query: 130 PGQYGQDLLIPPPP--PGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMA 187
L PP P AP P Q S P L +PP AP P L+ PP P +
Sbjct: 523 LQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP----LQAPPSP-LT 577
Query: 188 PPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVP--APAPPAPASPHTV 245
PPP +++ P + P++ +PP P+PPL+ LA PPP P PP A P
Sbjct: 578 TPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPS-- 635
Query: 246 GTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSP-AEPKGSALGPNPEPHLTFPRSFKV 304
PP ASPP SP A P A PN F
Sbjct: 636 -----PP---------------------ASPPLSPLATPSPQA--PNALAVHLLQAPFSP 667
Query: 305 PPPTPVRT-----SSIPVQEAQEAPRKEEGATKKAPSRL-PLPPSFHIRPASQVYPDRAP 358
PP PV+ +S PV + P + + P ++ P PP+ S P +AP
Sbjct: 668 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 727
Query: 359 EPDC--PGELKATAPASPRLGQSQSQADERAGTPPPAPPL----PPPAPPLPPPAPPLPP 412
P P ++ + PASP + S A PP PPL P PP PP + P+ P
Sbjct: 728 PPLAAPPLQVPPSPPASPPMSPS-------ATPPPRVPPLLAAPPLQVPPSPPASLPMSP 780
Query: 413 AAPPLPCAQKA-AHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLR 471
A P P A A A PP +P PA P P SP + +P+ P L
Sbjct: 781 LAKPPPQAPPALATPPLQALPSP----PASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 836
Query: 472 NELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPG-VPEK 530
L + R PT P + GPRL TL P PP P
Sbjct: 837 APLLQVPPSPPASPTLQAPRRPPTPGPDT--SVSGPRL----TLALAPGPPPPPSRSPSS 890
Query: 531 SLGGSSLTETEAAPSLT 547
+L G L ++ + T
Sbjct: 891 TLSGPDLAGHSSSATST 907
Score = 98.6 bits (244), Expect = 3e-20
Identities = 128/445 (28%), Positives = 167/445 (37%), Gaps = 68/445 (15%)
Query: 73 PRVRPLLTFLPLNAQEN---HGLAVPTPSVPDDFADKEVTGTSSL-VNGNLRLYSSVGDL 128
P+ P L PL + LA P P P A + S + L ++
Sbjct: 592 PQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQ 651
Query: 129 RPGQYGQDLLIPP--PPPGPAPGPPQDISEPPGGSPLPSPPSTAPPP---PPLLLEPPPP 183
P LL P PPP P P P SP +PPS APP PPL + P PP
Sbjct: 652 APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 711
Query: 184 PSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPP----APPLAFLAPPPPPVP--APAPP 237
S PP+ + +PP + P + PP +PP +PP++ A PPP VP APP
Sbjct: 712 AS-----PPMSPSATPPPQ-APPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPP 765
Query: 238 APASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPP-RSPAEPKGSALGPNP-EPH 295
P PP + S +A QA A+PP ++ P S G P P
Sbjct: 766 LQVPPS-------PPASLP--MSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 816
Query: 296 LTFPRS-FKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPP----------SF 344
+ P S PPP + P+ Q P T +AP R P P +
Sbjct: 817 ASLPMSPLATPPPQAPPVLAAPL--LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL 874
Query: 345 HIRPASQVYPDRAPE-----PDCPG-ELKATAPASPRLGQSQSQADERAGTPPPAPPLPP 398
+ P P R+P PD G AT+ G A +PPP L
Sbjct: 875 ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA 934
Query: 399 --PAPPLPPPAPPLP-PAAPPLPCAQKAAHPPAGF--------TKTPKSSSP---ALKPK 444
PA PAPPL AP P A P T+ P+S++P AL P
Sbjct: 935 CHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPG 994
Query: 445 PNPPSPENTASS---APVDWRDPSQ 466
P+P + A++ A R P Q
Sbjct: 995 PSPGTSGGKAAAGAGAGASSRSPKQ 1019
Score = 82.0 bits (201), Expect = 3e-15
Identities = 171/709 (24%), Positives = 232/709 (32%), Gaps = 103/709 (14%)
Query: 376 LGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPL--------------PCAQ 421
+ + +A A PA P P PP +P PP P P A+
Sbjct: 1 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60
Query: 422 KAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGS 481
+A G P+S+ A + S N AS P R + +N +
Sbjct: 61 RAG--GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRG-ERAPPAKNTSPGPVSSP 117
Query: 482 RREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTP----------------- 524
R + RPGP G+KG R+ +ET+ A + P
Sbjct: 118 GRASG--TTRPGPL-------GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT 168
Query: 525 PGVPEKSLG-GSSLTETEAAPSLTLPSV-DYIPQDSPTPSVRQIRNELEARLSSAAEKEA 582
PG P ++ S TE PS P + P SV S AA +
Sbjct: 169 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR-- 226
Query: 583 KPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPK-----AML 637
+PS G +P R + A LS P + T P QPK A+
Sbjct: 227 RPSAGGGLQRP---ASRSLSSSA--TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR 281
Query: 638 GPAI-PPKATPEPAIPPKATLWPATP-PKATLGPATPLKATSGPTTPLKATSGPAIASTA 695
P + PP+ PA+ P ++ ATP P T A P+ TPL AT P+ A
Sbjct: 282 PPQVTPPRKDAAPALGPLSSSPLATPSPSGT--KARPVPPPDNAATPLPATLPPS-PPLA 338
Query: 696 TTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFP 755
T LP P P+ Q + +P +P T P Q S P
Sbjct: 339 TPLPL-----------APPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIP 387
Query: 756 PKTSPGGGEVPCLYKP--HCHQSSLSREVAVVMPTLARGGA---AGPGEPVEVKEPPGLP 810
P P P L P SSL ++ PTL + P + P P
Sbjct: 388 PIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRP 447
Query: 811 AKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRD 870
A P + P L P + + SP L++ +++ SL
Sbjct: 448 ASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQAL----------SSLAS 497
Query: 871 HSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELS 930
HS QA SS I T +S A +P +P+ P L L+
Sbjct: 498 HSPQAPLSS-LIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL--QTASAPLT 554
Query: 931 RRHNWTKPEP-----QAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEV 985
H T P P QAP + P P P + P S + +
Sbjct: 555 TPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPL 614
Query: 986 IPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPAL 1034
PPP+ PP AL L SPP + L L P AP AL
Sbjct: 615 ATPPPQ-----APPXLALPPLQAPPSPPAS--PPLSPLATPSPQAPNAL 656
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 148 bits (373), Expect = 3e-35
Identities = 165/677 (24%), Positives = 226/677 (33%), Gaps = 94/677 (13%)
Query: 141 PPPPGPAPGPPQDISEPPGGSPLP------SPPSTAPPPPPLLLEPPPPPSMAPPPPPVL 194
PP P+P P + PP +P P +PP T P PP+ PPP+ P PP
Sbjct: 1401 PPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPIST 1460
Query: 195 EALSPPHTLSSPSIPTP-PDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPG 253
PP T SP TP P P+PP PPP P+PP T + PP
Sbjct: 1461 TTTPPPTTTPSPPTTTPSPPTTTPSPPTT-TTTTPPPTTTPSPPTT-------TPITPP- 1511
Query: 254 GVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTS 313
A T P +P+ P + P P + P + + PPT T+
Sbjct: 1512 ---------------ASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPT--STT 1554
Query: 314 SIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPAS 373
++P P T P+ P PP+ P+ P P T +
Sbjct: 1555 TLPPTTTPSPP--PTTTTTPPPTTTPSPPT-TTTPSPPTITTTTPPPTTTPSPPTTTTTT 1611
Query: 374 PRLGQSQSQADERAGTPPPA-PPLPPPAPPLPPPAPPL--PPAAPPLPCAQKAAHPPAGF 430
P + S TPP + LPP P PPP PP P P PP
Sbjct: 1612 PPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITT 1671
Query: 431 TKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSH 490
T TP ++ P PSP T + P PS ++ S +
Sbjct: 1672 TTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTT- 1730
Query: 491 RPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPS 550
P PT P P T+ +LP T + L S T + S T P+
Sbjct: 1731 -PSPTTTPS----------PPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPT 1779
Query: 551 VDYIP-------QDSPTPSVRQIRNELE-----------ARLSSAAEKEAKPSIGSLPPK 592
+P DS P+ + + E A +S A IG L
Sbjct: 1780 TPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQT 1839
Query: 593 P--RLEGGRICENGADDDKLSKPVAKNL-----------PPQSTTLLPTTSLQPKAMLGP 639
+ G IC+N P+A L Q TT+ TT+ P
Sbjct: 1840 VVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTT 1899
Query: 640 AIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTP----------LKATSGP 689
I T P P T P T P T TP +G TP + T P
Sbjct: 1900 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP 1959
Query: 690 AIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGAR 749
T TT P TT+ + + P G + P + ++T + +P+ T
Sbjct: 1960 TGTQTPTTTPITTTTTVTPTPT-PTG-TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2017
Query: 750 SSAAFPPKTSPGGGEVP 766
++ P +P G + P
Sbjct: 2018 TTTTVTPTPTPTGTQTP 2034
Score = 104 bits (259), Expect = 6e-22
Identities = 140/686 (20%), Positives = 215/686 (31%), Gaps = 81/686 (11%)
Query: 140 PPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPS--MAPPP-----PP 192
P PP P PP + P + PSPP+T PP P PP + + PP PP
Sbjct: 1578 PSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPP 1637
Query: 193 VLEALSPPHTLSSP---SIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRL 249
PP T ++P + P+PP P+PP+ PPP P+ P +P T +
Sbjct: 1638 TTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPIT-TTTTPPPTTTPSSPITTTPSPPTTTM 1696
Query: 250 FPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTP 309
P T S + + T SPP + P+P P T +P
Sbjct: 1697 TTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSP-PTTTMTTLPPTTTSSP 1755
Query: 310 VRTSSIPVQEAQEAPRKEEGATKKAPSRLPL----------PPSFHIRP----------- 348
+ T+ +P T P +PL P+FH +P
Sbjct: 1756 LTTTPLPPSITPPTFSPFSTTTPTTPC-VPLCNWTGWLDSGKPNFH-KPGGDTELIGDVC 1813
Query: 349 ----ASQVYPDRAPEPDCP-GELKATAPASPRLGQSQSQADERAG--------------- 388
A+ + PD P G+L T +G D++ G
Sbjct: 1814 GPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINV 1873
Query: 389 ------TPPPAPPLPPPAPPLPPPAPPL--PPAAPPLPCAQKAAHPPAGFTKTPKSSSPA 440
T P P PP P+ P P P T TP +++
Sbjct: 1874 QCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTP----TTTPITTTTT 1929
Query: 441 LKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQS 500
+ P P P + T ++ P+ ++ P PT
Sbjct: 1930 VTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT----- 1983
Query: 501 KEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPT 560
G + P T ++ TP G + + +T T P+ P +P
Sbjct: 1984 --GTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPI 2039
Query: 561 PSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPP 620
+ + + + ++ P P G + + V P
Sbjct: 2040 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ--TPTTTPITTTTTVTPTPTP 2097
Query: 621 QSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPT 680
T TT + + P P T P P T TP G TP T
Sbjct: 2098 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2157
Query: 681 TPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEA 740
T + T P T TT P TT+ + + P G + P + ++T + +P+
Sbjct: 2158 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTG-TQTPTTTPITTTTTVTPTPTPTGT 2215
Query: 741 TRLPTQGARSSAAFPPKTSPGGGEVP 766
T ++ P +P G + P
Sbjct: 2216 QTPTTTPITTTTTVTPTPTPTGTQTP 2241
Score = 86.3 bits (212), Expect = 2e-16
Identities = 98/442 (22%), Positives = 133/442 (30%), Gaps = 84/442 (19%)
Query: 331 TKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTP 390
T P+ P PP P S P P T P + + T
Sbjct: 1398 TPSPPTTTPSPP-----PTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTT 1452
Query: 391 PPAPPL------PPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPK 444
P+PP+ PP P PP P PP P P PP T +P +++P P
Sbjct: 1453 TPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPA 1512
Query: 445 PNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGK 504
P T S P + P PT P
Sbjct: 1513 STTTLPPTTTPSPPTT---------------------------TTTTPPPTTTPSPPTTT 1545
Query: 505 KGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVR 564
P P T P T P P + T T + P+ T PS I +P P+
Sbjct: 1546 --PITPPTSTTTLPPT--TTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTT 1601
Query: 565 QIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTT 624
+ P+ + P P + P+ P +TT
Sbjct: 1602 P----------------SPPTTTTTTPPPTT---------TPSPPTTTPITP--PTSTTT 1634
Query: 625 LLPTTSLQPKAMLGPAIPPKATPEP--AIPPKATLWPATPPKATLGPATPLKATSGPTTP 682
L PTT+ P PP TP P P + T P T P++P+ T P T
Sbjct: 1635 LPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTT 1694
Query: 683 LKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEA-T 741
T P ++ TTT + P ++TPS P+ T
Sbjct: 1695 TMTTPSPTTTPSSPITTTTTPS---------STTTPSPPPTTMTTPSPTTTPSPPTTTMT 1745
Query: 742 RLP---TQGARSSAAFPPKTSP 760
LP T ++ PP +P
Sbjct: 1746 TLPPTTTSSPLTTTPLPPSITP 1767
Score = 85.9 bits (211), Expect = 2e-16
Identities = 98/399 (24%), Positives = 121/399 (30%), Gaps = 82/399 (20%)
Query: 389 TPPPAPPLPPPA-----PPLPPPAPPL------PPAAPPLPCAQKAAHPPAGFTKTPKSS 437
+PP P PPP PP P+PP PP P P PP T +P S
Sbjct: 1400 SPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPIS 1459
Query: 438 SPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVA 497
+ P PSP T S P P + P PT
Sbjct: 1460 TTTTPPPTTTPSPPTTTPSPPTTTPSPPTTT--------------------TTTPPPTTT 1499
Query: 498 PQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQD 557
P P T ++ PA T +P + T T P T PS
Sbjct: 1500 PS----------PPTTTPITPPASTTT--LPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1547
Query: 558 SPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKN 617
+P S L P+ + PP S P
Sbjct: 1548 TPPTST--------TTLPPTTTPSPPPTTTTTPPPTTTP--------------SPPTTTT 1585
Query: 618 LPPQS---TTLLPTTSLQPKAMLGPAIPPKATPE-----PAIPPKA--TLWPATPPKATL 667
P + TT PTT+ P PP TP P PP + TL P T P
Sbjct: 1586 PSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPP 1645
Query: 668 GPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVST 727
T T+ P+ P T P I +T T PTTT S P P + ++T
Sbjct: 1646 TTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTT-------PSSPITTTPSPPTTTMTT 1698
Query: 728 PSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVP 766
PS SP T P+ S T+P P
Sbjct: 1699 PSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTP 1737
Score = 84.7 bits (208), Expect = 5e-16
Identities = 109/485 (22%), Positives = 137/485 (28%), Gaps = 99/485 (20%)
Query: 173 PPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVP 232
P + P PP+ P PPP PP T SP T PPP
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTT--------------TTTPPPTT 1436
Query: 233 APAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNP 292
P+PP + T PP T T PP + P + P+P
Sbjct: 1437 TPSPP-------ITTTTTPPPTTTP--------SPPISTTTTPPPTTTPSPPTTT--PSP 1479
Query: 293 EPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQV 352
P + P P T S P P T P+ P PP+ +
Sbjct: 1480 PTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPAS---TTTLPPTTTPSPPT-----TTTT 1531
Query: 353 YPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPP---APP 409
P P P T P S PP P PPP PP P
Sbjct: 1532 TPPPTTTPSPPTTTPITPPTSTTT------------LPPTTTPSPPPTTTTTPPPTTTPS 1579
Query: 410 LPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEK 469
P P P PP T +P +++ P PSP T P P+
Sbjct: 1580 PPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP-----PTSTTT 1634
Query: 470 LRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPE 529
L PT P T + P T P P
Sbjct: 1635 LP----------------------PTTTPSPPP-----------TTTTTPPPTTTPSPPT 1661
Query: 530 KSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSL 589
+ +T T P T PS SP P+ SS PS +
Sbjct: 1662 TTTPSPPITTTTTPPPTTTPSSPITTTPSP-PTTTMTTPSPTTTPSSPITTTTTPSSTTT 1720
Query: 590 PPKPRLEGGRICENGADDDKLSKPVAK--NLPPQSTTLLPTTSLQPKAMLGPAIPPKATP 647
P P + S P LPP +T+ TT+ P ++ P P +T
Sbjct: 1721 PSPPPTT----MTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTT 1776
Query: 648 EPAIP 652
P P
Sbjct: 1777 TPTTP 1781
Score = 81.6 bits (200), Expect = 4e-15
Identities = 110/459 (23%), Positives = 142/459 (30%), Gaps = 83/459 (18%)
Query: 258 WKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPV 317
W D + T SPP + P+P T P P+ T++ P
Sbjct: 1390 WPMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPP 1449
Query: 318 QEAQEAP------RKEEGATKKAPSRLPLPPSFHIRP--ASQVYPDRAPEPDCPGELKAT 369
+P T P+ P PP+ P + P P P T
Sbjct: 1450 PTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT 1509
Query: 370 APASPRL---GQSQSQADERAGTPPP-APPLPPPAPPLPPP--APPLPPAAPPLPCAQKA 423
PAS + S TPPP P PP P+ PP LPP P P
Sbjct: 1510 PPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSP----- 1564
Query: 424 AHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRR 483
PP T P +++P+ P PSP ++ P PS
Sbjct: 1565 --PPTTTTTPPPTTTPS-PPTTTTPSPPTITTTTPPPTTTPS------------------ 1603
Query: 484 EDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAA 543
+ P PT P P P T P T P P + T T +
Sbjct: 1604 PPTTTTTTPPPTTTPSPP--TTTPITPPTSTTTLPPT--TTPSPPPTTTTTPPPTTTPSP 1659
Query: 544 PSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICEN 603
P+ T PS +P P+ S + P+ P P
Sbjct: 1660 PTTTTPSPPITTTTTPPPTT--------TPSSPITTTPSPPTTTMTTPSPTTTP------ 1705
Query: 604 GADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPP 663
S P+ P STT T S P M P+ P TP P TL PP
Sbjct: 1706 -------SSPITTTTTPSSTT---TPSPPPTTMTTPS--PTTTPSPPTTTMTTL----PP 1749
Query: 664 KATLGPATPLKATSGPTTPL-KATSGPAIASTATTLPTT 701
T P T TTPL + + P + +TT PTT
Sbjct: 1750 TTTSSPLT--------TTPLPPSITPPTFSPFSTTTPTT 1780
Score = 79.3 bits (194), Expect = 2e-14
Identities = 145/795 (18%), Positives = 233/795 (29%), Gaps = 55/795 (6%)
Query: 60 TVSESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNL 119
TV+ + T T P P+ T + PTP+ +T T+++
Sbjct: 3562 TVTPTPTPTGTQTPTTTPITTTTTVTP-------TPTPTGTQTPTTTPITTTTTVTPTPT 3614
Query: 120 RLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSP-----PSTAPPPP 174
+ P + P P G I+ +P P+P P+T P
Sbjct: 3615 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3674
Query: 175 PLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAP 234
+ P P P+ P + P T ++ PTP P + P P
Sbjct: 3675 TTTVTPTPTPTGTQTPT------TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3728
Query: 235 APPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALG---PN 291
P +P T P T G Q T + P + G P
Sbjct: 3729 TPTGTQTPTTT-----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3783
Query: 292 PEPHLTFPRSFKVPPPTPVRT-SSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPAS 350
P T P PT +T ++ P+ + P+ P+ + + P
Sbjct: 3784 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3843
Query: 351 QVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPL 410
+ P P T +P +Q+ T P P P P P+
Sbjct: 3844 TPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3902
Query: 411 PPAAP--PLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQME 468
P P P T TP +++ + P P P + T ++ P+
Sbjct: 3903 TTTTTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT 3957
Query: 469 KLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVP 528
++ P PT G + P T ++ TP G
Sbjct: 3958 PTPTGTQTPTTTPITTTTTVTPTPTPT-------GTQTPTTTPITTTTTVTPTPTPTGTQ 4010
Query: 529 EKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGS 588
+ + +T T P+ P +P + + + + +
Sbjct: 4011 TPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4068
Query: 589 LPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPE 648
+ P P G + + V P T TT + + P P T
Sbjct: 4069 VTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4126
Query: 649 PAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAE 708
P P T TP G TP TT + T P T TT P TT+ +
Sbjct: 4127 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4186
Query: 709 KDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCL 768
+ P G P + + P +P + P +S+ T+ +
Sbjct: 4187 TPT-PTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTT-----LLST 4240
Query: 769 YKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAK---PPASAQPTDELLR 825
P +S + PT GG P PPG P + +S+ PT ++
Sbjct: 4241 LPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQ 4300
Query: 826 HPVTGEVVERGSPMA 840
T +P++
Sbjct: 4301 TTTTSAWTPTPTPLS 4315
Score = 74.3 bits (181), Expect = 6e-13
Identities = 140/698 (20%), Positives = 220/698 (31%), Gaps = 72/698 (10%)
Query: 60 TVSESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNL 119
TV+ + T T P P+ T + PTP+ +T T+++
Sbjct: 3677 TVTPTPTPTGTQTPTTTPITTTTTVTP-------TPTPTGTQTPTTTPITTTTTVTPTPT 3729
Query: 120 RLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSP-----PSTAPPPP 174
+ P + P P G I+ +P P+P P+T P
Sbjct: 3730 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3789
Query: 175 PLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAP 234
+ P P P+ P + P T ++ PTP P + P P
Sbjct: 3790 TTTVTPTPTPTGTQTPT------TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3843
Query: 235 APPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALG---PN 291
P +P T P T G Q T + P + G P
Sbjct: 3844 TPTGTQTPTTT-----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3898
Query: 292 PEPHLTFPRSFKVPPPTPVRT-SSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPAS 350
P T P PT +T ++ P+ + P+ P+ + + P
Sbjct: 3899 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3958
Query: 351 QVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPL 410
+ P P T +P +Q+ T P P P P P+
Sbjct: 3959 TPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4017
Query: 411 PPAAP--PLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQME 468
P P P T TP +++ + P P P + T ++ P+
Sbjct: 4018 TTTTTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT 4072
Query: 469 KLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVP 528
++ P PT G + P T ++ TP G
Sbjct: 4073 PTPTGTQTPTTTPITTTTTVTPTPTPT-------GTQTPTTTPITTTTTVTPTPTPTGTQ 4125
Query: 529 EKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGS 588
+ + +T T P+ P +P + + + + +
Sbjct: 4126 TPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 4183
Query: 589 LPPKPRLEGGRICENGADDDKLSKPVAK----NLPPQSTTLLPTTSLQPKAMLGPAIPPK 644
+ P P G + G + P+A+ N PP+S+T P TS + L +
Sbjct: 4184 VTPTPTPTG---TQTGPPTHTSTAPIAELTTSNPPPESST--PQTSRSTSSPLTESTTLL 4238
Query: 645 ATPEPAIPPKATLWPATP--PKATLGPAT----PLKATSGPTTPLKATS-GPAIASTATT 697
+T PAI +T P+TP P T G T P TS P TP + T+ G + A T +T
Sbjct: 4239 STLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPST 4298
Query: 698 LPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEG 735
+ TTT+ P +STPS R G
Sbjct: 4299 VQTTTTSAWT------------PTPTPLSTPSIIRTTG 4324
Score = 73.2 bits (178), Expect = 1e-12
Identities = 171/927 (18%), Positives = 270/927 (29%), Gaps = 78/927 (8%)
Query: 60 TVSESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNL 119
TV+ + T T P P+ T + PTP+ +T T+++
Sbjct: 3447 TVTPTPTPTGTQTPTTTPITTTTTVTP-------TPTPTGTQTPTTTPITTTTTVTPTPT 3499
Query: 120 RLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSP-----PSTAPPPP 174
+ P + P P G I+ +P P+P P+T P
Sbjct: 3500 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3559
Query: 175 PLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAP 234
+ P P P+ P + P T ++ PTP P + P P
Sbjct: 3560 TTTVTPTPTPTGTQTPT------TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3613
Query: 235 APPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALG---PN 291
P +P T P T G Q T + P + G P
Sbjct: 3614 TPTGTQTPTTT-----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3668
Query: 292 PEPHLTFPRSFKVPPPTPVRT-SSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPAS 350
P T P PT +T ++ P+ + P+ P+ + + P
Sbjct: 3669 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3728
Query: 351 QVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPL 410
+ P P T +P +Q+ T P P P P P+
Sbjct: 3729 TPTGTQTPTTT-PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3787
Query: 411 PPAAP--PLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQME 468
P P P T TP +++ + P P P + T ++ P+
Sbjct: 3788 TTTTTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT 3842
Query: 469 KLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVP 528
++ P PT G + P T ++ TP G
Sbjct: 3843 PTPTGTQTPTTTPITTTTTVTPTPTPT-------GTQTPTTTPITTTTTVTPTPTPTGTQ 3895
Query: 529 EKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGS 588
+ + +T T P+ P +P + + + + +
Sbjct: 3896 TPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3953
Query: 589 LPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPE 648
+ P P G + + V P T TT + + P P T
Sbjct: 3954 VTPTPTPTGTQTPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 4011
Query: 649 PAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAE 708
P P T TP G TP TT + T P T TT P TT+ +
Sbjct: 4012 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 4071
Query: 709 KDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCL 768
+ P G + P + ++T + +P+ T ++ P +P G + P
Sbjct: 4072 TPT-PTG-TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-- 4127
Query: 769 YKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQ-PTDELLRHP 827
++ V PT G P P P Q PT P
Sbjct: 4128 ------TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT----P 4177
Query: 828 VTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLP-GSLRDHSHQAEASSDSIFHSQ 886
+T +P G G S+ P L + E+S+ S
Sbjct: 4178 ITTTTTVTPTP----------TPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRST 4227
Query: 887 GTP--NSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPV 944
+P S T++ LP E S P G G LS + T P P
Sbjct: 4228 SSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSG----GHTLSPPPSTTTSPPGTPT 4283
Query: 945 AWERVAPSNLPQGHPLPKSFSSPPSPS 971
S+ P + + +S +P+
Sbjct: 4284 RGTTTGSSSAPTPSTVQTTTTSAWTPT 4310
Score = 71.6 bits (174), Expect = 4e-12
Identities = 131/718 (18%), Positives = 212/718 (29%), Gaps = 48/718 (6%)
Query: 60 TVSESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNL 119
TV+ + T T P P+ T + PTP+ +T T+++
Sbjct: 2090 TVTPTPTPTGTQTPTTTPITTTTTVTP-------TPTPTGTQTPTTTPITTTTTVTPTPT 2142
Query: 120 RLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSP-----PSTAPPPP 174
+ P + P P G I+ +P P+P P+T P
Sbjct: 2143 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2202
Query: 175 PLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAP 234
+ P P P+ P + P T ++ PTP P + P P
Sbjct: 2203 TTTVTPTPTPTGTQTPT------TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2256
Query: 235 APPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALG---PN 291
P +P T P T G Q T + P + G P
Sbjct: 2257 TPTGTQTPTTT-----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2311
Query: 292 PEPHLTFPRSFKVPPPTPVRT-SSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPAS 350
P T P PT +T ++ P+ + P+ P+ + + P
Sbjct: 2312 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2371
Query: 351 QVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPL 410
+ P P T +P +Q+ T P P P P P+
Sbjct: 2372 TPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2430
Query: 411 --PPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQME 468
P P P T TP +++ + P P P + T ++ P+
Sbjct: 2431 TTTTTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT 2485
Query: 469 KLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVP 528
++ P PT G + P T ++ TP G
Sbjct: 2486 PTPTGTQTPTTTPITTTTTVTPTPTPT-------GTQTPTTTPITTTTTVTPTPTPTGTQ 2538
Query: 529 EKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGS 588
+ + +T T P+ P +P + + + + +
Sbjct: 2539 TPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2596
Query: 589 LPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPE 648
+ P P G + + V P T TT + + P P T
Sbjct: 2597 VTPTPTPTGTQ--TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2654
Query: 649 PAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAE 708
P P T TP G TP TT + T P T TT P TT+ +
Sbjct: 2655 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2714
Query: 709 KDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVP 766
+ P G + P + ++T + +P+ T ++ P +P G + P
Sbjct: 2715 TPT-PTG-TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2770
Score = 71.6 bits (174), Expect = 4e-12
Identities = 131/718 (18%), Positives = 212/718 (29%), Gaps = 48/718 (6%)
Query: 60 TVSESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNL 119
TV+ + T T P P+ T + PTP+ +T T+++
Sbjct: 2550 TVTPTPTPTGTQTPTTTPITTTTTVTP-------TPTPTGTQTPTTTPITTTTTVTPTPT 2602
Query: 120 RLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSP-----PSTAPPPP 174
+ P + P P G I+ +P P+P P+T P
Sbjct: 2603 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2662
Query: 175 PLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAP 234
+ P P P+ P + P T ++ PTP P + P P
Sbjct: 2663 TTTVTPTPTPTGTQTPT------TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2716
Query: 235 APPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALG---PN 291
P +P T P T G Q T + P + G P
Sbjct: 2717 TPTGTQTPTTT-----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2771
Query: 292 PEPHLTFPRSFKVPPPTPVRT-SSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPAS 350
P T P PT +T ++ P+ + P+ P+ + + P
Sbjct: 2772 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2831
Query: 351 QVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPL 410
+ P P T +P +Q+ T P P P P P+
Sbjct: 2832 TPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2890
Query: 411 --PPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQME 468
P P P T TP +++ + P P P + T ++ P+
Sbjct: 2891 TTTTTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT 2945
Query: 469 KLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVP 528
++ P PT G + P T ++ TP G
Sbjct: 2946 PTPTGTQTPTTTPITTTTTVTPTPTPT-------GTQTPTTTPITTTTTVTPTPTPTGTQ 2998
Query: 529 EKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGS 588
+ + +T T P+ P +P + + + + +
Sbjct: 2999 TPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3056
Query: 589 LPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPE 648
+ P P G + + V P T TT + + P P T
Sbjct: 3057 VTPTPTPTGTQ--TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3114
Query: 649 PAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAE 708
P P T TP G TP TT + T P T TT P TT+ +
Sbjct: 3115 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3174
Query: 709 KDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVP 766
+ P G + P + ++T + +P+ T ++ P +P G + P
Sbjct: 3175 TPT-PTG-TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3230
Score = 71.6 bits (174), Expect = 4e-12
Identities = 131/718 (18%), Positives = 212/718 (29%), Gaps = 48/718 (6%)
Query: 60 TVSESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNL 119
TV+ + T T P P+ T + PTP+ +T T+++
Sbjct: 3010 TVTPTPTPTGTQTPTTTPITTTTTVTP-------TPTPTGTQTPTTTPITTTTTVTPTPT 3062
Query: 120 RLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSP-----PSTAPPPP 174
+ P + P P G I+ +P P+P P+T P
Sbjct: 3063 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3122
Query: 175 PLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAP 234
+ P P P+ P + P T ++ PTP P + P P
Sbjct: 3123 TTTVTPTPTPTGTQTPT------TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3176
Query: 235 APPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALG---PN 291
P +P T P T G Q T + P + G P
Sbjct: 3177 TPTGTQTPTTT-----PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3231
Query: 292 PEPHLTFPRSFKVPPPTPVRT-SSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPAS 350
P T P PT +T ++ P+ + P+ P+ + + P
Sbjct: 3232 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3291
Query: 351 QVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPL 410
+ P P T +P +Q+ T P P P P P+
Sbjct: 3292 TPTGTQTP-TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3350
Query: 411 --PPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQME 468
P P P T TP +++ + P P P + T ++ P+
Sbjct: 3351 TTTTTVTPTPTPTGTQTP----TTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT 3405
Query: 469 KLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVP 528
++ P PT G + P T ++ TP G
Sbjct: 3406 PTPTGTQTPTTTPITTTTTVTPTPTPT-------GTQTPTTTPITTTTTVTPTPTPTGTQ 3458
Query: 529 EKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGS 588
+ + +T T P+ P +P + + + + +
Sbjct: 3459 TPTT--TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 3516
Query: 589 LPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPE 648
+ P P G + + V P T TT + + P P T
Sbjct: 3517 VTPTPTPTGTQ--TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3574
Query: 649 PAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAE 708
P P T TP G TP TT + T P T TT P TT+ +
Sbjct: 3575 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 3634
Query: 709 KDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVP 766
+ P G + P + ++T + +P+ T ++ P +P G + P
Sbjct: 3635 TPT-PTG-TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3690
Score = 70.5 bits (171), Expect = 9e-12
Identities = 118/637 (18%), Positives = 188/637 (29%), Gaps = 41/637 (6%)
Query: 141 PPPPGPAPGPPQDISEPPGGSPLPSP-----PSTAPPPPPLLLEPPPPPSMAPPPPPVLE 195
P P G I+ +P P+P P+T P + P P P+ P
Sbjct: 1934 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT---- 1989
Query: 196 ALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGV 255
+ P T ++ PTP P + P P P +P T P
Sbjct: 1990 --TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT-----PITTT 2042
Query: 256 TKWKSDVALNGRQAEATRASPPRSPAEPKGSALG---PNPEPHLTFPRSFKVPPPTPVRT 312
T G Q T + P + G P P T P PT +T
Sbjct: 2043 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2102
Query: 313 -SSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAP 371
++ P+ + P+ P+ + + P + P P T
Sbjct: 2103 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-TTTPITTTTTVT 2161
Query: 372 ASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPL--PPAAPPLPCAQKAAHPPAG 429
+P +Q+ T P P P P P+ P P P
Sbjct: 2162 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP--- 2218
Query: 430 FTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLS 489
T TP +++ + P P P + T ++ P+ ++
Sbjct: 2219 -TTTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2276
Query: 490 HRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLP 549
P PT G + P T ++ TP G + + +T T P
Sbjct: 2277 PTPTPT-------GTQTPTTTPITTTTTVTPTPTPTGTQTPTT--TPITTTTTVTPTPTP 2327
Query: 550 SVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDK 609
+ P +P + + + + ++ P P G +
Sbjct: 2328 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ--TPTTTPIT 2385
Query: 610 LSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGP 669
+ V P T TT + + P P T P P T TP G
Sbjct: 2386 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2445
Query: 670 ATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPS 729
TP TT + T P T TT P TT+ + + P G + P + ++T +
Sbjct: 2446 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-PTG-TQTPTTTPITTTT 2503
Query: 730 QARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVP 766
+P+ T ++ P +P G + P
Sbjct: 2504 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2540
Score = 63.5 bits (153), Expect = 1e-09
Identities = 56/215 (26%), Positives = 73/215 (33%), Gaps = 23/215 (10%)
Query: 610 LSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGP 669
+ K + PP +T P TS +PP TP PP T T P T P
Sbjct: 1392 MDKCITTPSPPTTTPSPPPTST-------TTLPPTTTPS---PPTTT---TTTPPPTTTP 1438
Query: 670 ATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPS 729
+ P+ T+ P P T P I++T T PTTT S P P P + + P
Sbjct: 1439 SPPITTTTTP--PPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPP 1496
Query: 730 QARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMP-- 787
+PS T P S+ PP T+P P S + P
Sbjct: 1497 TT----TPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTS 1552
Query: 788 --TLARGGAAGPGEPVEVKEPPGLPAKPPASAQPT 820
TL P PP PP + P+
Sbjct: 1553 TTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPS 1587
Score = 54.7 bits (130), Expect = 5e-07
Identities = 89/382 (23%), Positives = 121/382 (31%), Gaps = 80/382 (20%)
Query: 60 TVSESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNL 119
TV+ + T T P P+ T + PTP+ +T T+++
Sbjct: 4091 TVTPTPTPTGTQTPTTTPITTTTTVTP-------TPTPTGTQTPTTTPITTTTTVTPTPT 4143
Query: 120 RLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLE 179
+ P + P P G I+ +P P+P T PP
Sbjct: 4144 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTST 4203
Query: 180 PPPPPSMAPPPPPVLEALSPPHTLSSPSIP-----TPPDFIPPAPPLAFLAPPPPPVPAP 234
P PPP S P T S S P T +PPA + APP P
Sbjct: 4204 APIAELTTSNPPP---ESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPT--- 4257
Query: 235 APPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAE--PKGSALGPNP 292
AP + HT L PP +T SPP +P GS+ P P
Sbjct: 4258 APTTTSGGHT----LSPP-----------------PSTTTSPPGTPTRGTTTGSSSAPTP 4296
Query: 293 EPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHI------ 346
T S P PTP+ T SI + P P S I
Sbjct: 4297 STVQTTTTSAWTPTPTPLSTPSII----------------RTTGLRPYPSSVLICCVLND 4340
Query: 347 ---RPASQVYPDRAPEP--------DCPGEL-KATAPASPRLGQSQSQADERAGTPPPAP 394
P +VY + C E + P++P + S++ TP P+
Sbjct: 4341 TYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKS-----TPTPSK 4395
Query: 395 PLPPPAPPLPPPAPPLPPAAPP 416
P P+ P P PP P P
Sbjct: 4396 PSSTPSKPTPGTKPPECPDFDP 4417
Score = 33.5 bits (75), Expect = 1.2
Identities = 17/49 (34%), Positives = 21/49 (42%), Gaps = 7/49 (14%)
Query: 141 PPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPP 189
P P P P P + +P PS PS+ P P +PP P PP
Sbjct: 4377 PSTPSPTPTPSK-------STPTPSKPSSTPSKPTPGTKPPECPDFDPP 4418
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 137 bits (346), Expect = 5e-32
Identities = 131/376 (34%), Positives = 151/376 (40%), Gaps = 76/376 (20%)
Query: 130 PGQYGQDLLIPPPPPGPAPG--PPQDISEPPGGSPLPSPP---STAPPPPPL--LLEPPP 182
P G ++L PPPPP P G PP + PG LP PP + PPPPPL PPP
Sbjct: 900 PPLQGTEMLPPPPPPLPGAGIPPPPPL---PGAGILPLPPLPGAGIPPPPPLPGAAIPPP 956
Query: 183 PP---SMAPPPPPVLEA-LSPPHTLSSPSIPTPPDF----IPPAPPLAFLA-PPPPPVP- 232
PP + P PPP+ A + PP L IP PP IPP PPL PPPPP+P
Sbjct: 957 PPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG 1016
Query: 233 APAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNP 292
A PP P P G + PP A P P P P P
Sbjct: 1017 AGIPPPPPLP---GAGIPPP----------------PPLPGAGIPPPPPLPGAGIPPPPP 1057
Query: 293 EPHLTFP-----RSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLP---LPPSF 344
P P +PPP P+ + IP P GA P LP +PP
Sbjct: 1058 LPGAGIPPPPPLPGAGIPPPPPLPGAGIP------PPPPLPGAGIPPPPPLPGVGIPPPP 1111
Query: 345 HIRPASQVYPDR-------APEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLP 397
+ P + + P P P PG P PR+G AG PPP PPLP
Sbjct: 1112 PL-PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPP-PPLP 1169
Query: 398 ----PPAPPLP----PPAPPLP----PAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKP 445
PP PPLP PP PPLP P PPLP A PP P + +P L P
Sbjct: 1170 GAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPG 1229
Query: 446 N--PPSPENTASSAPV 459
PP P S P+
Sbjct: 1230 TGIPPPPLLPVSGPPL 1245
Score = 112 bits (279), Expect = 3e-24
Identities = 116/338 (34%), Positives = 125/338 (36%), Gaps = 60/338 (17%)
Query: 139 IPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAP----PPPPLLLEPPPPP----SMAPPP 190
IP PPP P + S PG +P PP P P P P PPP M PPP
Sbjct: 855 IPSPPPLPCT---ESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPP 911
Query: 191 PPVLEALSPPHTLSSPSIPTPPDFIPPAPPL--AFLAPPPPPVPAPAPPAPASPHTVGTR 248
PP L P P P P I P PPL A + PPPPP+P A P P G
Sbjct: 912 PPPLPGAGIP-----PPPPLPGAGILPLPPLPGAGI-PPPPPLPGAAIPPPPPLPGAGIP 965
Query: 249 LFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPT 308
L PP L G A P P P P P P +PPP
Sbjct: 966 LPPPLPGAGIPPPPPLPG-------AGIPPPPPLPGAGIPPPPPLP------GAGIPPPP 1012
Query: 309 PVRTSSIPVQEAQEAPRKEEGATKKAPSRLP---LPPSFHIRPASQVYPDRAPEPDCPGE 365
P+ + IP P GA P LP +PP P P P PG
Sbjct: 1013 PLPGAGIP------PPPPLPGAGIPPPPPLPGAGIPP-----PPPLPGAGIPPPPPLPGA 1061
Query: 366 LKATAPASPRLGQSQSQADERAGTPPPAPPLP----PPAPPLP----PPAPPLP----PA 413
P P G AG PPP PPLP PP PPLP PP PPLP P
Sbjct: 1062 GIPPPPPLPGAGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPP 1120
Query: 414 APPLPCAQKAAHPP-AGFTKTPKSSSPALKPKPNPPSP 450
PPLP A PP G P P + P PP P
Sbjct: 1121 PPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLP 1158
Score = 107 bits (267), Expect = 7e-23
Identities = 106/310 (34%), Positives = 118/310 (38%), Gaps = 52/310 (16%)
Query: 139 IPPPPPGPAPGPPQDISEPPGGSPLPSPPSTA--PPPPPLLLE--PPPPP---SMAPPPP 191
IPPPPP P G P P G P P P A PPPPPL PPPPP + PPPP
Sbjct: 986 IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP 1045
Query: 192 PVLEA-LSPPHTLSSPSIPTPPDF----IPPAPPLAFLA-PPPPPVPAPAPPAPASPHTV 245
P+ A + PP L IP PP IPP PPL PPPPP+P P P V
Sbjct: 1046 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGV 1105
Query: 246 GTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVP 305
G PP L G A P P P P P P + +P
Sbjct: 1106 GIPPPPPLPGAGIPPPPPLPG-------AGIPPPPPLPGAGIPPPPPLPRVG------IP 1152
Query: 306 PPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLP---LPPSFHIRPASQVYPDRAPEPDC 362
PP P+ + IP P GA P LP +PP P P P
Sbjct: 1153 PPPPLPGAGIP------PPPPLPGAGIPPPPPLPGVGIPP-----PPPLPGVGIPPPPPL 1201
Query: 363 PGELKATAPASPRLGQSQSQADERAGTPPPAPPLP---PPAPPLPPPAPPLPP--AAPPL 417
PG P P +G + A PP PP PP P LP PPL P + L
Sbjct: 1202 PGAGIPPPPPLPGMGIPPAPA-------PPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTL 1254
Query: 418 PCAQKAAHPP 427
P Q P
Sbjct: 1255 PTPQVCGFLP 1264
Score = 105 bits (263), Expect = 2e-22
Identities = 170/640 (26%), Positives = 207/640 (32%), Gaps = 176/640 (27%)
Query: 140 PPPPPGPAPGP-------------PQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSM 186
PP PPG GP P+ IS S PPPP LL
Sbjct: 767 PPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPG 826
Query: 187 APPPPPVLEALSPPHTLS-------SPSIPTPP-----DFIPPAPPLAFLAPPPPPVPA- 233
+ PP + H S S +IP+PP + P L + PPPPP+P
Sbjct: 827 SQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGM 886
Query: 234 -----PAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSAL 288
P+ P P GT + PP L G A P P P L
Sbjct: 887 TVPTLPSTAIPQPPPLQGTEMLPP-------PPPPLPG-------AGIPPPPPLPGAGIL 932
Query: 289 GPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRP 348
P P +PPP P+ ++IP P GA +PLPP P
Sbjct: 933 PLPPLP------GAGIPPPPPLPGAAIP------PPPPLPGA------GIPLPPPL---P 971
Query: 349 ASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLP----PPAPPLP 404
+ + P P PG P P G AG PPP PPLP PP PPLP
Sbjct: 972 GAGI----PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP-PPLPGAGIPPPPPLP 1026
Query: 405 ----PPAPPLP----PAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPN---PPSPENT 453
PP PPLP P PPLP A PP P + P P P PP P
Sbjct: 1027 GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP-----LPGAGIPPPPPLPGAGIPPPPPLP 1081
Query: 454 ASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKE 513
+ P P + PG + P P LP
Sbjct: 1082 GAGIP----PPPPL------------------------PGAGIPPP-------PPLPG-- 1104
Query: 514 TLLSLPAKDTPPGV---PEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNEL 570
+ +P PG P L G+ + P +P P P + ++
Sbjct: 1105 --VGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIP---------PPPPLPRVGIPP 1153
Query: 571 EARLSSAAEKEAKPSIGS-LPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTT 629
L A P G+ +PP P L G +PP LP
Sbjct: 1154 PPPLPGAGIPPPPPLPGAGIPPPPPLPG------------------VGIPPPPP--LPGV 1193
Query: 630 SLQPKAML-GPAI-PPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATS 687
+ P L G I PP P IPP P PP T P PL SGP PL
Sbjct: 1194 GIPPPPPLPGAGIPPPPPLPGMGIPPAPA--PPLPPPGTGIPPPPLLPVSGP--PLLPQV 1249
Query: 688 GPAIASTATT-------LPTTTSQLMAEKDSGPAGQPEKP 720
G + T LP+ L +D G QP +P
Sbjct: 1250 GSSTLPTPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEP 1289
Score = 37.4 bits (85), Expect = 0.086
Identities = 51/206 (24%), Positives = 68/206 (33%), Gaps = 34/206 (16%)
Query: 160 GSPLPSPPSTAPPPPP--------LLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTP 211
G+ P+ P TA P P LL P AP P +ALS L P
Sbjct: 228 GAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEP 287
Query: 212 PDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGR---- 267
+ P P P +PA P A SP + FP G + + + G
Sbjct: 288 REPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFP-FPEAGPGEEAAGAPVRGAGDTD 346
Query: 268 ---QAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQ--E 322
+ +A +P SP E +G + P R P +EAQ +
Sbjct: 347 EEGEEDAFEDAPRGSPGEEWAPEVGED----------------APQRLGEEPEEEAQGPD 390
Query: 323 APRKEEGATKKAPSRLPLPPSFHIRP 348
AP APS+ P I P
Sbjct: 391 APAAASLPGSPAPSQRCFKPYPLITP 416
Score = 37.4 bits (85), Expect = 0.086
Identities = 35/116 (30%), Positives = 40/116 (34%), Gaps = 23/116 (19%)
Query: 938 PEPQAPVAWERVAP----SNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFS 993
P P P A P + +P PLP + PP P IPPPP
Sbjct: 1043 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG----------IPPPPPLP 1092
Query: 994 NDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPALGFSRFPAGARYAGAG 1049
PP P L +G PP LP AG PP L + P GAG
Sbjct: 1093 GAGIPPPPPLPGVGIPPPPP---------LPGAGIPPPPPLPGAGIPPPPPLPGAG 1139
Score = 36.6 bits (83), Expect = 0.15
Identities = 35/117 (29%), Positives = 40/117 (34%), Gaps = 14/117 (11%)
Query: 938 PEPQAPVAWERVAP----SNLPQGHPLPKSFSSPPSP-SNKREEEEEEFNFEVIPPPPEF 992
P P P A + P + +P PLP + PP P IPPPP
Sbjct: 955 PPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1014
Query: 993 SNDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPALGFSRFPAGARYAGAG 1049
PP P L G PP LP AG PP L + P GAG
Sbjct: 1015 PGAGIPPPPPLPGAGIPPPPP---------LPGAGIPPPPPLPGAGIPPPPPLPGAG 1062
Score = 36.6 bits (83), Expect = 0.15
Identities = 35/116 (30%), Positives = 39/116 (33%), Gaps = 23/116 (19%)
Query: 938 PEPQAPVAWERVAP----SNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFS 993
P P P A P + +P PLP + PP P IPPPP
Sbjct: 999 PPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG----------IPPPPPLP 1048
Query: 994 NDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPALGFSRFPAGARYAGAG 1049
PP P L G PP LP AG PP L + P GAG
Sbjct: 1049 GAGIPPPPPLPGAGIPPPPP---------LPGAGIPPPPPLPGAGIPPPPPLPGAG 1095
Score = 35.4 bits (80), Expect = 0.33
Identities = 29/96 (30%), Positives = 33/96 (34%), Gaps = 19/96 (19%)
Query: 954 LPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPP 1013
+P PLP + PP P IPPPP PP P L +G PP
Sbjct: 1107 IPPPPPLPGAGIPPPPPLPGAG----------IPPPPPLPGAGIPPPPPLPRVGIPPPPP 1156
Query: 1014 RNNYSDLRQLPNAGPGAPPALGFSRFPAGARYAGAG 1049
LP AG PP L + P G G
Sbjct: 1157 ---------LPGAGIPPPPPLPGAGIPPPPPLPGVG 1183
Score = 35.0 bits (79), Expect = 0.43
Identities = 60/235 (25%), Positives = 84/235 (35%), Gaps = 29/235 (12%)
Query: 370 APASPRLGQSQSQAD---ERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHP 426
AP SP Q+ S E P P PP LP AP LP AQ AA
Sbjct: 263 APGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLP------VSEAPSLPAAQPAA-- 314
Query: 427 PAGFTKTPKSSSPALKPKPNPPS-PENTASSAPVDWRDPSQMEKLRNELAAYLCGSRRED 485
SP+ P P + P A+ APV + E + GS E+
Sbjct: 315 ---------KDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEE 365
Query: 486 --RFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAA 543
+ + + +E +GP P +L PA P + + T
Sbjct: 366 WAPEVGEDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTT--- 422
Query: 544 PSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGG 598
+ L S ++ P SP S R I+ E LS + + A S+ + K R +GG
Sbjct: 423 -TRQLSSPNHSPSQSPNQSPR-IKRRPEPSLSRGS-RTALASVAAPAKKHRADGG 474
Score = 35.0 bits (79), Expect = 0.43
Identities = 35/117 (29%), Positives = 39/117 (33%), Gaps = 14/117 (11%)
Query: 938 PEPQAPVAWERVAP----SNLPQGHPLPKSFSSPPSP-SNKREEEEEEFNFEVIPPPPEF 992
P P P A P + +P PLP + PP P IPPPP
Sbjct: 922 PPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPL 981
Query: 993 SNDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPALGFSRFPAGARYAGAG 1049
PP P L G PP LP AG PP L + P GAG
Sbjct: 982 PGAGIPPPPPLPGAGIPPPPP---------LPGAGIPPPPPLPGAGIPPPPPLPGAG 1029
Score = 34.7 bits (78), Expect = 0.56
Identities = 47/179 (26%), Positives = 55/179 (30%), Gaps = 45/179 (25%)
Query: 938 PEPQAPVAWERVAP----SNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFS 993
P P P A P + +P PLP+ PP P IPPPP
Sbjct: 1120 PPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAG----------IPPPPPLP 1169
Query: 994 NDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPALGFSRFPAGARYAGAGGLER 1053
PP P L +G PP LP G PP L + P G G
Sbjct: 1170 GAGIPPPPPLPGVGIPPPPP---------LPGVGIPPPPPLPGAGIPPPPPLPGMG---- 1216
Query: 1054 FSGGGRSLIKKRLYVGEPHRGPGLPHGGTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPP 1112
P P LP GTG P P G P + +V S+ P
Sbjct: 1217 ---------------IPPAPAPPLPPPGTG---IPPPPLLPVSGPPLLPQVGSSTLPTP 1257
Score = 33.9 bits (76), Expect = 0.95
Identities = 48/177 (27%), Positives = 59/177 (33%), Gaps = 36/177 (20%)
Query: 277 PRSP-AEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAP 335
P SP E SAL PE PR P P +PV EA P + A K +P
Sbjct: 264 PGSPDTEQALSALSDLPESLAAEPRE----PQQPPSPGGLPVSEAPSLPAAQPAA-KDSP 318
Query: 336 SRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPA-----SPRLGQSQSQADERAGTP 390
S P +P+ P GE A AP + G+ + D G+P
Sbjct: 319 SSTAFP-----------FPEAGP-----GEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSP 362
Query: 391 PP--APPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKP 445
AP + AP P P P A A +P S KP P
Sbjct: 363 GEEWAPEVGEDAPQRLGEEPEEEAQGPDAPAA-------ASLPGSPAPSQRCFKPYP 412
Score = 32.7 bits (73), Expect = 2.1
Identities = 33/110 (30%), Positives = 36/110 (32%), Gaps = 13/110 (11%)
Query: 953 NLPQGHPLPKSFSS---------PPSPSNKREEEEEEFNFEVIPPPPEFSNDP--EPPAP 1001
N+P PLP + SS PP P IP PP PP P
Sbjct: 854 NIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPP 913
Query: 1002 ALQYLGRQSSPPRNNYS--DLRQLPNAGPGAPPALGFSRFPAGARYAGAG 1049
L G PP L LP AG PP L + P GAG
Sbjct: 914 PLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAG 963
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 133 bits (334), Expect = 1e-30
Identities = 251/1025 (24%), Positives = 344/1025 (33%), Gaps = 218/1025 (21%)
Query: 138 LIPPPPPGPAPGPPQD--ISEPPGGSPLPSPPSTAPPPP---------PLL---LEPPPP 183
L+PPP P PP++ S PP S L PP P P PL L PPP
Sbjct: 440 LLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPE 499
Query: 184 PSMAPPPP------PVLEA-LSPPH-TLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPA 235
S PPP P+ E+ LSPP + SP++ TP + P P + L+PP P
Sbjct: 500 ESPLSPPPESSPFSPLEESPLSPPEESPPSPALETP---LSPPPEASPLSPPFEESPLSP 556
Query: 236 PP--APASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPE 293
PP P SP +RL PP E + SPP P+ S + P PE
Sbjct: 557 PPEELPTSPPPEASRLSPP----------------PEESPMSPP-----PEESPMSPPPE 595
Query: 294 PHLTFPRSFKVP--PPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPAS- 350
FP + P PP S P + ++ +P E+ P P+ P + S
Sbjct: 596 ASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSP 655
Query: 351 -QVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAG--TPPPAPPLPPPAPPLPPPA 407
V +P P+ +P SP +S + A +PPP P P P +
Sbjct: 656 LPVVSRLSPPPE-------ESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPAS 708
Query: 408 PPLPPAAPPLPCAQKAAHP-PAGFTKTPKSSSPALKPKPNPP--SPENTASSAPVDWRDP 464
PP + LP + P P P+S P L P+P P SP +P
Sbjct: 709 PPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEP 768
Query: 465 SQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTP 524
+ LC E GP ++PQ +E P+ E
Sbjct: 769 HLSPQPEEPC---LCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHL---------- 815
Query: 525 PGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKP 584
VPE+ E+ +P P + SP P + ELE KP
Sbjct: 816 SPVPEEPCLSPQPEESHLSPQSEEPCL------SPRPEESHLSPELE-----------KP 858
Query: 585 SIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPK 644
+ P KP E G+ P + LP L P + L P +
Sbjct: 859 PLSPRPEKPPEEPGQC------------PAPEELP-----LFPPPG---EPSLSPLLGEP 898
Query: 645 ATPEPAIPPKATLWPATPPKATLGPA--TPLKATSGPTTPLKATSGPAIASTATTLPTTT 702
A EP PP + L P + L P+ L P PL P I + A +
Sbjct: 899 ALSEPGEPPLSPL----PEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPL 954
Query: 703 SQLMAEKDSGPAGQPEKP-ASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKT-SP 760
+L + PE P A+ + TP E + ++ +P PP SP
Sbjct: 955 GELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPM------ILPPSPGSP 1008
Query: 761 GGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQP- 819
G P L +P Q S L + P PP LP P+ P
Sbjct: 1009 VGPASPILMEPLPPQCS----------PLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPI 1058
Query: 820 ------TDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSH 873
+DE H + E V AL +A S LP + D S
Sbjct: 1059 GKVVGVSDEAELHEMETEKVSEPECPALEPSA---------------TSPLPSPMGDLSC 1103
Query: 874 QAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRH 933
A + + ++ G + + D+P + P + L + +G+ +
Sbjct: 1104 PAPSPAPALDDFSGLGEDTAPLDGI------DAPGSQPEPGQTPGSLASELKGSPV---- 1153
Query: 934 NWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPP--- 990
PE APV V +P K + SP EE+EE V P PP
Sbjct: 1154 -LLDPEELAPVTPMEV--------YPECKQTAGQGSPC----EEQEEPRAPVAPTPPTLI 1200
Query: 991 ------EFSN--------------------DPEPPAPALQYLGRQSS-PPRNNYSDLRQL 1023
E SN DPE LG + P + LR
Sbjct: 1201 KSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTDVSPARDEGSLRLC 1260
Query: 1024 PNAGPGAPPALGFSRFPA--GARYAGAGGLERFSGGGRSLIKKRLYVGEP--HRGPGLPH 1079
++ P +L A G + G G R S RS IK+ P R G H
Sbjct: 1261 TDSLPETDDSLLCDAGTAISGGKAEGEKGRRR-SSPARSRIKQGRSSSFPGRRRPRGGAH 1319
Query: 1080 GGTGR 1084
GG GR
Sbjct: 1320 GGRGR 1324
Score = 83.2 bits (204), Expect = 1e-15
Identities = 237/982 (24%), Positives = 327/982 (33%), Gaps = 184/982 (18%)
Query: 101 DDFADKEVTGTSSLVNGNLRLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEP--- 157
D+ A + + + VGD+ L + PP A G P + P
Sbjct: 2066 DNRAAHRINKVQKQAESQINKQTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIF 2125
Query: 158 ------PGG----------SPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPH 201
P G P S P P L PP P+ P P L+P +
Sbjct: 2126 IGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPF--GLAPAY 2183
Query: 202 TLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKS- 260
L P PT P PP P PP + A + P P T PPG S
Sbjct: 2184 PL-EPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTT--PPGTPRHQPST 2240
Query: 261 -DVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQE 319
D L R + P SP G A EP L+ PPP ++
Sbjct: 2241 PDPFLKPRCPSLDNLAVPESPGVGGGKA----SEPLLS-------PPPFG------ESRK 2283
Query: 320 AQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQS 379
A E ++E GA+ +PS P F P+S + E P K AP +PR Q
Sbjct: 2284 ALEVKKEELGAS--SPSYGPPNLGFVDSPSSGTHLG-GLELKTPDVFK--APLTPRASQV 2338
Query: 380 QSQADE---RAGTPPPA---PPLPPPAPPL--------PPPAPPLPPAAPPLPCAQKAAH 425
+ Q+ R PPPA P PP P + P PPL P P P A
Sbjct: 2339 EPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCAL 2398
Query: 426 PPAGFTKTPKSSSPALKPKPNPPSPENTASS-APVDWRDPSQMEKLRNELAAYLCGSRRE 484
PP P S PA SP++ +SS +P+ R S A C S
Sbjct: 2399 PPRSLPSDPFSRVPA--------SPQSQSSSQSPLTPRPLS---------AEAFCPSPVT 2441
Query: 485 DRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEK-------SLG-GSS 536
RF S P P P S+ + P P L P + PP V K SLG G
Sbjct: 2442 PRFQS--PDPYSRPPSRPQSRDPFAP-----LHKPPRPQPPEVAFKAGSLAHTSLGAGGF 2494
Query: 537 LTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSA-----AEKEAKPSIGSLPP 591
A P+ L + +P P VR S + +PS+ P
Sbjct: 2495 PAALPAGPAGELHA--KVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVP 2552
Query: 592 KPRLEGGR-ICENGADDDKLSKP-------VAKNLPPQSTTLLPTTSLQPKAM-LGPAIP 642
+P L I + L KP N P + L P++ ++ L P P
Sbjct: 2553 QPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRP 2612
Query: 643 PKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTT 702
P P PA P +L P + G + SG T+P++ P T T
Sbjct: 2613 PSVLPPPA--PDGSL-----PYLSHGAS----QRSGITSPVEKREDP---GTGMGSSLAT 2658
Query: 703 SQLMAEKDSGPAG--------QPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAF 754
++L +D G +G Q ++ +E+ Q + E T A + A
Sbjct: 2659 AELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEK---ETAAAAAGAVG 2715
Query: 755 PP------KTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPG---EPVEVKE 805
PP +SP ++ P S V + P+ G GPG +
Sbjct: 2716 PPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVG-LPPSKLSGPILGPGSFPSDDRLSR 2774
Query: 806 PPGLPAKPPASAQPTDELLRHPVTG-EVVERGSPMALLLAARQRAQKGRSVGAALGRSSL 864
PP PPA+ D R V G + + +P L +Q+ Q+
Sbjct: 2775 PP-----PPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQ------------- 2816
Query: 865 PGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPL---TTEIPNKWGPRLG 921
L A+S S P+ T P+L ++A SPL +T +P P G
Sbjct: 2817 ---LWQQQQATAATSMRFAMSARFPS--TPGPELGRQA-LGSPLAGISTRLPGPGEPVPG 2870
Query: 922 RDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEF 981
+ RHN K + P P+ +P+ + P E
Sbjct: 2871 PAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSE------DPHRLAPEGLRGL 2924
Query: 982 NFEVIPPPPEFSNDPEPPAPAL 1003
+PP PPAP L
Sbjct: 2925 AVSGLPP----QKPSAPPAPEL 2942
Score = 66.2 bits (160), Expect = 2e-10
Identities = 123/451 (27%), Positives = 168/451 (37%), Gaps = 102/451 (22%)
Query: 130 PGQYG--QDLLIPPPPPGPAPGP---PQDISEP--PGGSPLP-----SP---PSTAP--- 171
PGQ ++L + PPP P+ P +SEP P SPLP SP PS +P
Sbjct: 871 PGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLM 930
Query: 172 PPPPLLLEPPPPPSMAPPPPPVLEAL-------------SPPHTLSSPSIPTPPDFIPPA 218
PP PL PP P + PP L L P L++P + TP I P
Sbjct: 931 PPDPL--PPPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETP---ISP- 984
Query: 219 PPLAFLAPPPPPVPAPAPPAPASPHTVGTRL----FPPGGVTKWKSDVALNGRQAEATRA 274
PP A P P P PP+P SP + + PP + +L + + ++
Sbjct: 985 PPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQH--SLVPQNSPPSQC 1042
Query: 275 SPPR------SPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEE 328
SPP SP P G +G + E L + KV P E P E
Sbjct: 1043 SPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEP--------------ECPALEP 1088
Query: 329 GATKKAPSRL-----PLP-PSFHIRPASQVYPDRAPEP--DCPGELKATAPASPRLGQSQ 380
AT PS + P P P+ + S + D AP D PG + P GQ+
Sbjct: 1089 SATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPG-------SQPEPGQTP 1141
Query: 381 -SQADERAGTPPPAPP--LPPPAP---------------PLPPPAPPLPPAAPPLPCAQK 422
S A E G+P P L P P P P P AP P K
Sbjct: 1142 GSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAPTPPTLIK 1201
Query: 423 A--AHPPAGFTKTPKSSS-PALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLC 479
+ + + ++ S+S P +P P PE S ++ + + R+E + LC
Sbjct: 1202 SDIVNEISNLSQGDASASFPGSEPLLGSPDPEG-GGSLSMELGVSTDVSPARDEGSLRLC 1260
Query: 480 GSR--REDRFLSHRPGPTVAPQSKEGKKGPR 508
D L G ++ EG+KG R
Sbjct: 1261 TDSLPETDDSLLCDAGTAISGGKAEGEKGRR 1291
Score = 63.2 bits (152), Expect = 1e-09
Identities = 118/499 (23%), Positives = 167/499 (33%), Gaps = 104/499 (20%)
Query: 64 SGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNLRLYS 123
S L+ VR L QE L + P++ +F+ G+ VNG +L
Sbjct: 4534 SSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRG 4593
Query: 124 SVGD----LRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLE 179
+ G P Y Q L ++S PP +PPS+ PP PP ++
Sbjct: 4594 AFGSGALPTGPDYYSQLLT------------KNNLSNPP------TPPSSLPPTPPPSVQ 4635
Query: 180 PP------PPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIP--PAPP------LAFLA 225
P + P A L S D + P PP + +
Sbjct: 4636 QKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMES 4695
Query: 226 PPPPPVPAPAPPAPASPHTVGTRL--FPPGGVTKWKS-DVALNGRQAEATRASPPRSPAE 282
P PA + +G FP G +W+ D AL+ RAS P P
Sbjct: 4696 DEDSDSPDSIVPASSPESILGEEAPRFPHLGSGRWEQEDRALSPVIPLIPRASIPVFPDT 4755
Query: 283 PKGSALG---PNPEPHLTFPR-------------------------------SFKVP--- 305
ALG P P T+ + S K+P
Sbjct: 4756 KPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSY 4815
Query: 306 ----PPTPVRTSSIPVQEAQEAPR-KEEGATKKAPSRLP--------LPPSFHIRPASQV 352
P +P R + P + E P KE+G K+P P + P + ++ +
Sbjct: 4816 EVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDI 4875
Query: 353 YP---DRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPP 409
+P P+ P + T S L Q A PPP P PPP+P P PA P
Sbjct: 4876 LSLLKQESPAPEPPTQHSYTYNVS-NLDVRQLSA------PPPEEPSPPPSPLAPSPASP 4928
Query: 410 LPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAP---VDWRDPSQ 466
LP + A PP SS + +PKP PE S P W+ +
Sbjct: 4929 PTEPLVELP-TEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLKKWKG-VR 4986
Query: 467 MEKLRNELAAYLCGSRRED 485
++LR L R+ED
Sbjct: 4987 WKRLRLLLTIQKGSGRQED 5005
Score = 58.9 bits (141), Expect = 3e-08
Identities = 167/769 (21%), Positives = 247/769 (32%), Gaps = 98/769 (12%)
Query: 144 PGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTL 203
PGP GP Q++ G P P P P PP L P + P PPP
Sbjct: 4267 PGPQTGPLQEL----GAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPP----------- 4311
Query: 204 SSPSIPTPPDFIP-PAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDV 262
SSP P P +P P+ L A PP P P P P T PPG V+ + +
Sbjct: 4312 SSPQEPKRPSQLPSPSSQLPTEAQLPP--THPGTPKPQGP----TLEPPPGRVSPAAAQL 4365
Query: 263 ALNGRQAEATRASPPRSPAE---PKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQE 319
A PP + AE P+ S+L P HL VP + + P +E
Sbjct: 4366 ADTLFSKGLGPWDPPDNLAETQKPEQSSLVPG---HLDQVNGQVVPEASQLSIKQEPREE 4422
Query: 320 -----AQEAPRKEEGATKKAPSRL-------PLPPSFHIRPASQVYPDRAPEPDCPGELK 367
AQ R+ G AP P + H+ + G
Sbjct: 4423 PCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEG 4482
Query: 368 ATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPP 427
A + + + +++ P PL P + A+ L ++K
Sbjct: 4483 LRAEINGHIDSKLAGLEQKLQGTPSNKEDAAARKPLTPKPKRVQKASDRLVSSRKKLRKE 4542
Query: 428 AGFTKTPK-----SSSPALKPKPNPPSPENTASSAPVDWRDP-SQMEKLRNEL--AAYLC 479
G + +L P P N + AP P + +LR A
Sbjct: 4543 DGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPT 4602
Query: 480 GSRREDRFL--SHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDT---PPGVPEKSLGG 534
G + L ++ P P S P + +K P+++ P
Sbjct: 4603 GPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSE 4662
Query: 535 SSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSI-GSLPPK- 592
+L +T SL L + P + T VR +E S + SI G P+
Sbjct: 4663 RALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRF 4722
Query: 593 PRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIP 652
P L GR +D+ PV +P S + P T +P LG +P K
Sbjct: 4723 PHLGSGR----WEQEDRALSPVIPLIPRASIPVFPDT--KPYGALGLEVPGKL------- 4769
Query: 653 PKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEK--D 710
P T + G + T A A + ++L++ K +
Sbjct: 4770 ----------------PVTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPN 4813
Query: 711 SGPAGQPEKPASQEVSTPSQARGEGSPSEATRL--------PTQGARSSAAFPPKTSPGG 762
S PE PA + + P + EG + L P + A P T
Sbjct: 4814 SYEVLFPESPA-RAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQ 4872
Query: 763 GEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDE 822
++ L K + + P E PP P P ++ PT+
Sbjct: 4873 LDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEP 4932
Query: 823 LLRHPVTGEVVERGSPMALLLAARQRA--QKGRSVGAALGRSSLPGSLR 869
L+ P T + E P L LA+ + K R+ G S P L+
Sbjct: 4933 LVELP-TEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLK 4980
Score = 57.0 bits (136), Expect = 1e-07
Identities = 212/933 (22%), Positives = 289/933 (30%), Gaps = 181/933 (19%)
Query: 195 EALSPPHTLSSPSIP--------TPPDFIPPAP----PLAFLAPPPPPVPAPAP------ 236
EA S PH L+ PS+ T P P P+ P PP P P
Sbjct: 4126 EASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGL 4185
Query: 237 PAPASPHTVGTRLFPPGGVT-------------KWKSDVALNGRQAEATRASPPRSPAEP 283
P TVG GV + + L RQ + ++A P +
Sbjct: 4186 PGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQE 4245
Query: 284 KGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPP- 342
G+ P P+ P P + P+QE PR + P RLP PP
Sbjct: 4246 PGTQTSPLQGLLGCQPQLGGFPGP-----QTGPLQELGAGPRPQ------GPPRLPAPPG 4294
Query: 343 SFHIRPA-SQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPP-A 400
+ P V+P P P P E K + +L SQ A PP P P P
Sbjct: 4295 ALSTGPVLGPVHP--TPPPSSPQEPKRPS----QLPSPSSQLPTEAQLPPTHPGTPKPQG 4348
Query: 401 PPLPPPAPPLPPAAPPLPCAQKAA-----HPPAGFTKTPKSSSPALKPK----------- 444
P L PP + PAA L + PP +T K +L P
Sbjct: 4349 PTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVP 4408
Query: 445 -------PNPPSPENTASSAPVDWRD----PSQMEKLRNELAAYLCGSRREDRFLSHRP- 492
P E A A R+ P N L L G R E L +
Sbjct: 4409 EASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLL--LAGPRSEAGHLLLQKL 4466
Query: 493 --GPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPS 550
V + G +G R + S A G+ +K G S E AA P
Sbjct: 4467 LRAKNVQLSTGRGSEGLRAEINGHIDSKLA-----GLEQKLQGTPSNKEDAAARKPLTPK 4521
Query: 551 VDYIPQ--DSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDD 608
+ + D S +++R E R S A K+ K + LP L I N +
Sbjct: 4522 PKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLP----LTEPAITANFS--- 4574
Query: 609 KLSKPVAKNLPPQSTTLLPTTSLQPKAMLGP-----AIPPKATPEPAIPPKATLWPATPP 663
L P P + L GP + P PP + P TPP
Sbjct: 4575 -LFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSSL--PPTPP 4631
Query: 664 KATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQ 723
P+ K +G T + P A++A K P
Sbjct: 4632 -----PSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAALPTPPHN 4686
Query: 724 EVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSRE-- 781
+ E S S + +P S G E P PH +E
Sbjct: 4687 QTEDVRMESDEDSDSPDSIVPASSPESIL---------GEEAPRF--PHLGSGRWEQEDR 4735
Query: 782 -VAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMA 840
++ V+P + R P P P A + + PVT +GS ++
Sbjct: 4736 ALSPVIPLIPRASI------------PVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVS 4783
Query: 841 LLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVV-PKLP 899
++L A K + G + + L S PNS+ V+ P+ P
Sbjct: 4784 VMLTVSAAAAKNLN-GVMVAVAELL-------------------SMKIPNSYEVLFPESP 4823
Query: 900 KEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGH- 958
A + P E G G EG +W K ++ V P +
Sbjct: 4824 ARAGTE-PKKGEAEGPGGKEKG--LEGKSPDTGPDWLKQ-------FDAVLPGYTLKSQL 4873
Query: 959 ---PLPKSFSSPPSPSNKREEEEEEFNFEV----IPPPPEFSNDPEPPAPALQYLGRQSS 1011
L K S P P + N +V PPP E S P P AP+ +S
Sbjct: 4874 DILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPS------PAS 4927
Query: 1012 PPRNNYSDLRQLPNAGPGAPPALGFSRFPAGAR 1044
PP +L P A P P L + P AR
Sbjct: 4928 PPTEPLVELPTEPLAEPPVPSPLPLASSPESAR 4960
Score = 46.6 bits (109), Expect = 1e-04
Identities = 172/778 (22%), Positives = 253/778 (32%), Gaps = 149/778 (19%)
Query: 481 SRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETL------LSLPAKDTPPGVPEKSLGG 534
SR F S PG +P + G P P T LS + ++ LG
Sbjct: 1955 SRERGGFFSPEPGEPDSPWTGSGGTTPSTPTTPTTEGEGDGLSYNQRSLQRWEKDEELGQ 2014
Query: 535 SSLTETEAAPSLTLPSV--DYIPQDSPTPSVRQIRNELEAR-----LSSAAEKEAKPSIG 587
S ++ P++ DY S + ++ ++ A L A + A I
Sbjct: 2015 LSTISPVLYANINFPNLKQDYPDWSSRCKQIMKLWRKVPAADKAPYLQKAKDNRAAHRIN 2074
Query: 588 SLPPKPRLEGGRICENGADDDKLSKPVAK-NLPPQSTTL-LPTTSLQPKAMLGPAIPPKA 645
+ + + + + G K +P +PPQ L P + P +G P
Sbjct: 2075 KVQKQAESQINKQTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAG 2134
Query: 646 TPEPAI----PPKATL-WPATPPKA--TLGPATPLKATS------GPTTPLKATSGPAIA 692
A PP ++ P +P + L P P + S P PL+ P
Sbjct: 2135 LSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLE----PRFP 2190
Query: 693 STATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSA 752
+ T P S P G P +P S+ G G P E P R
Sbjct: 2191 TAPPTYPPYPS---------PTGAPAQPPMLGASSRP---GAGQPGEFHTTPPGTPRHQP 2238
Query: 753 AFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAK 812
+ P KP C P+L + + V E PG+
Sbjct: 2239 STPDP----------FLKPRC-------------PSL---------DNLAVPESPGV--- 2263
Query: 813 PPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAA-LGRSSLPGSLRDH 871
+ ++ LL P GE S AL + + S G LG P S H
Sbjct: 2264 --GGGKASEPLLSPPPFGE-----SRKALEVKKEELGASSPSYGPPNLGFVDSPSS-GTH 2315
Query: 872 SHQAEASSDSIFHSQGTPNSFTVVPKLP------KEAEKDSPLTTEIPNKWGPRLGRDAE 925
E + +F + TP + V P+ P +E L P+ P + R
Sbjct: 2316 LGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSH--PDIFRPGS 2373
Query: 926 GTELSRRHNWT-KPEPQAPVAWERVAPSNLPQGH-----PLPKSFSSPPSPSNKREEEEE 979
T+ + T +P+P P + + P +LP P+S SS SP R E
Sbjct: 2374 YTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAE 2433
Query: 980 EFNFEVIPP----PPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPALG 1035
F + P P +S P P + PPR ++ AG A +LG
Sbjct: 2434 AFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHK-PPRPQPPEVAF--KAGSLAHTSLG 2490
Query: 1036 FSRFPAGARYAGAGGLERF--SGGGRSLIKKR-----------------LYVGEPHRGPG 1076
FPA AG L SG + ++ VGEP P
Sbjct: 2491 AGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPP 2550
Query: 1077 LPHGGTGRSLSSPNCFGPQP--GGPEMRR--VNSAGRAPPGGLHAPRLSLEGAARGAAEA 1132
+P G + FGP P G P+ V + P G P G + G +
Sbjct: 2551 VPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPL 2610
Query: 1133 KHKA-------PGSADYGFAPAAGRSPYTT---------TRYGSPINTFTVRPGTRHP 1174
+ + GS Y A+ RS T+ T GS + T + PGT+ P
Sbjct: 2611 RPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAEL-PGTQDP 2667
Score = 46.2 bits (108), Expect = 2e-04
Identities = 101/438 (23%), Positives = 152/438 (34%), Gaps = 63/438 (14%)
Query: 621 QSTTLL-PTTSLQPKAMLGPAIPPKATPEPAIPPK--ATLWPATPPKATLGPATPLKATS 677
QS TLL P Q + LGP +P K + P TL + T+ PA +AT
Sbjct: 3980 QSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATE 4039
Query: 678 GPTTPLKATSGP-AIASTATTLPTTTSQLMAEKDSG-------PAGQPEKPASQEVSTPS 729
GP+T GP AI +T ++ T ++ P QP+ P+S ++ P
Sbjct: 4040 GPST---HQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQ-PSSLQLQPPL 4095
Query: 730 QARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTL 789
+ G+ + + L T G S +S VP L Q S+S P
Sbjct: 4096 RLPGQ-QQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLA----QPSVS---LGDQPGS 4147
Query: 790 ARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRA 849
GP +P+ + P + QP P G V++ G + +
Sbjct: 4148 MTQNLLGPQQPMLER-----PMQNNTGPQP-------PKPGPVLQSGQGLPGVGIMPTVG 4195
Query: 850 QKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTV--VPKLPKEAEKDSP 907
Q + L ++ LR S Q + ++ + S V P + + SP
Sbjct: 4196 QLRAQLQGVLAKNP---QLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSP 4252
Query: 908 LTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWER-------------VAPSNL 954
L + + P+LG + P PQ P V P+
Sbjct: 4253 LQGLLGCQ--PQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPP 4310
Query: 955 PQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPR 1014
P PK S PSPS++ E + PP P+P P L+ + SP
Sbjct: 4311 PSSPQEPKRPSQLPSPSSQLPTEAQ--------LPPTHPGTPKPQGPTLEPPPGRVSPAA 4362
Query: 1015 NNYSDLRQLPNAGPGAPP 1032
+D GP PP
Sbjct: 4363 AQLADTLFSKGLGPWDPP 4380
Score = 45.1 bits (105), Expect = 4e-04
Identities = 45/145 (31%), Positives = 57/145 (39%), Gaps = 12/145 (8%)
Query: 161 SPLPSPPS------TAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDF 214
SP P PP+ L PPP +PPP P+ + + P T +PT P
Sbjct: 4883 SPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLA 4942
Query: 215 IPPAP-PLAFLAPPPPPVPAP-APPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEAT 272
PP P PL + P P P A P + RL GV +WK L Q +
Sbjct: 4943 EPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLKKWKGV-RWKRLRLLLTIQKGSG 5001
Query: 273 RASPPRSPA---EPKGSALGPNPEP 294
R R A E G+AL P+ P
Sbjct: 5002 RQEDEREVAEFMEQLGTALRPDKVP 5026
Score = 43.9 bits (102), Expect = 0.001
Identities = 99/457 (21%), Positives = 139/457 (30%), Gaps = 102/457 (22%)
Query: 130 PGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAP-----PPPPLLLEPPPPP 184
PG ++ P P P P PQ EP S LPSP S P PP P P
Sbjct: 4293 PGALSTGPVLGPVHPTPPPSSPQ---EPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGP 4349
Query: 185 SMAPPPPPVLEALS---------------PPHTLSSPSIPTPPDFIP-----------PA 218
++ PPP V A + PP L+ P +P P
Sbjct: 4350 TLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPE 4409
Query: 219 PPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPG--------------------GVTKW 258
+ P P G + PG + +
Sbjct: 4410 ASQLSIKQEPREEPCALGAQSVKREANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRA 4469
Query: 259 KSDVALNGRQAEATRA------SPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRT 312
K+ GR +E RA + E K N E R P P V+
Sbjct: 4470 KNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKLQGTPSNKED--AAARKPLTPKPKRVQK 4527
Query: 313 SSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAP- 371
+S + +++ RKE+G L + P + EP AP
Sbjct: 4528 ASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLT--------EPAITANFSLFAPF 4579
Query: 372 --ASPRLGQSQSQADERAGTPPPA---------------PPLPPPA-PPLPPPAPPLPPA 413
P GQSQ + +G P PP PP + PP PPP+
Sbjct: 4580 GSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMV 4639
Query: 414 APPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNE 473
P + HP + + S AL+ S + A+ + +Q E +R E
Sbjct: 4640 NGVTPSEELGEHPKD--AASARDSERALRDTSEVKSLDLLAA---LPTPPHNQTEDVRME 4694
Query: 474 LAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLP 510
ED P +P+S G++ PR P
Sbjct: 4695 --------SDEDSDSPDSIVPASSPESILGEEAPRFP 4723
Score = 40.4 bits (93), Expect = 0.010
Identities = 44/198 (22%), Positives = 68/198 (34%), Gaps = 40/198 (20%)
Query: 273 RASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATK 332
R S P PA P S++ N + ++F P P S+P+Q+ Q+ +++ AT
Sbjct: 2771 RLSRPPPPATP--SSMDVNSRQLVGGSQAFYQRAPYP---GSLPLQQQQQQLWQQQQATA 2825
Query: 333 KAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQS------QSQADER 386
R + F P ++ P + P P G + + + + +
Sbjct: 2826 ATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQ 2885
Query: 387 AGTPPPAPPLPPPAPPLPPP-----------------------APPLPPAAPPLPCAQKA 423
G P P P PP P PP P+APP P +
Sbjct: 2886 KGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNS 2945
Query: 424 AHPPAGFTKTPKSSSPAL 441
HP TP + P L
Sbjct: 2946 LHP------TPHTKGPTL 2957
Score = 40.4 bits (93), Expect = 0.010
Identities = 136/636 (21%), Positives = 211/636 (33%), Gaps = 121/636 (19%)
Query: 427 PAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDR 486
P TP+S A +P PS + V + Q L+ + L G +++
Sbjct: 4048 PLAIGTTPESM--ATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQV 4105
Query: 487 FLSHRPGPTVAPQSKEGK--KGPRLPEKETLLSLPAKDTPPGVPEKSLGG---------- 534
L H G Q G + +P S+ D P + + LG
Sbjct: 4106 SLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQ 4165
Query: 535 SSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPR 594
++ P L S +P P+V Q+R +L+ L+ P + L P+ +
Sbjct: 4166 NNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAK------NPQLRHLSPQQQ 4219
Query: 595 LEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQ------------PKAMLGPAIP 642
+ + + PP T+ LQ P GP
Sbjct: 4220 QQLQALL---MQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQE 4276
Query: 643 PKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTT 702
A P P PP+ PA P + GP GP P S P + LP+ +
Sbjct: 4277 LGAGPRPQGPPRL---PAPPGALSTGPVL------GPVHPTPPPSSPQEPKRPSQLPSPS 4327
Query: 703 SQLMAE-----------KDSGPAGQPE----KPASQEVSTPSQARGEGSPSEATRL-PTQ 746
SQL E K GP +P PA+ +++ ++G G L TQ
Sbjct: 4328 SQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQ 4387
Query: 747 GARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEP 806
S+ P G+V P Q S+ +E R G +E
Sbjct: 4388 KPEQSSLVPGHLDQVNGQV----VPEASQLSIKQE--------PREEPCALGAQSVKREA 4435
Query: 807 PGLPAKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSS--L 864
G P P ++ LL P R LLL Q+ + ++V + GR S L
Sbjct: 4436 NGEPIGAPGTSNHL--LLAGP-------RSEAGHLLL---QKLLRAKNVQLSTGRGSEGL 4483
Query: 865 PGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDA 924
+ H A + QGTP++ ++A PLT + P+ + A
Sbjct: 4484 RAEINGHIDSKLAGLEQ--KLQGTPSN-------KEDAAARKPLTPK------PKRVQKA 4528
Query: 925 EGTELSRRHNWTKPE----PQAPVAWERVAPSNLPQGHP-LPKSFS-----SPPSPSNKR 974
+S R K + +A + + S LP P + +FS P N +
Sbjct: 4529 SDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQ 4588
Query: 975 EEEEEEFNFEVIPPPPEF----------SNDPEPPA 1000
+ F +P P++ SN P PP+
Sbjct: 4589 SQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPPS 4624
Score = 38.9 bits (89), Expect = 0.029
Identities = 36/114 (31%), Positives = 45/114 (39%), Gaps = 28/114 (24%)
Query: 142 PPPGPAPGPPQDISEP--------PGGSPLPSP-PSTAPPPPPLLLEP------------ 180
P PGPA GP Q I PGG+P P P P P+ +P
Sbjct: 2867 PVPGPA-GPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLA 2925
Query: 181 ----PPPPSMAPPPPPVLEALSP-PHTLSSPSIPTPPDFIPPAPPLAFLAPPPP 229
PP APP P + +L P PHT P++PT + + P L P P
Sbjct: 2926 VSGLPPQKPSAPPAPELNNSLHPTPHT-KGPTLPTGLELVNRPPSSTELGRPNP 2978
Score = 31.6 bits (70), Expect = 4.7
Identities = 82/323 (25%), Positives = 103/323 (31%), Gaps = 71/323 (21%)
Query: 173 PPPLLLEPPPPPSMAPPPPPVLEALSP--PHTLSSPSIPTPPDFIPPAPPLAFLAPPPPP 230
P PL E PPP+ P + L P P+P F P P
Sbjct: 3091 PGPLGPEERPPPAADASEPRLASVLPEVKPKVEEGGRHPSPCQF-------TIATPKVEP 3143
Query: 231 VPA---------PAPPAPASPHT-VGTRLFPPGGVTKWKSDV-ALNGRQAEATRASPPRS 279
PA P S T +GT F G T K+ A G A SP
Sbjct: 3144 APAANSLGLGLKPGQSMMGSRDTRMGTGPFSSSGHTAEKASFGATGGPPAHLLTPSPLSG 3203
Query: 280 PAEPKGSALGPNPEPH---LTFP-------------RSFKVPPPTPVRTSSIPVQEAQEA 323
P GS+L E LT P S V P+ + E +E
Sbjct: 3204 PG---GSSLLEKFELESGALTLPGGPAASGDELDKMESSLVASELPLLIEDLLEHEKKEL 3260
Query: 324 PRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEP--DCPGELKATA----PASPRLG 377
+K++ S ++PA Q + PG +A + +SP L
Sbjct: 3261 QKKQQ-------------LSAQLQPAQQQQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLA 3307
Query: 378 QSQSQAD-ERAGTPPPAPPLPPPAPPLPPPAPPLPP-AAPPLPCAQKAAHPPAG------ 429
SQ Q AG P LP P P PPA L AP + H +G
Sbjct: 3308 GSQQQLSLGLAGARQPG--LPQPLMPTQPPAHALQQRLAPSMAMVSNQGHMLSGQHGGQA 3365
Query: 430 FTKTPKSSSPALKPKP---NPPS 449
+SS P L KP PPS
Sbjct: 3366 GLVPQQSSQPVLSQKPMGTMPPS 3388
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 124 bits (312), Expect = 4e-28
Identities = 235/991 (23%), Positives = 330/991 (33%), Gaps = 208/991 (20%)
Query: 138 LIPPPPPGPAPGPPQDISEPPGGSPLPS--------PPSTAPPPPPLLLEPPPPPSMAPP 189
++ P PP GP + PGG PP PPPPL PPPPP PP
Sbjct: 205 VVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPL--PPPPPPPPPPP 262
Query: 190 PPPVLEALSPPHTLSSP----------------------------SIPTPPDFIPPA--- 218
PP A SPP L+ P S+P P + PA
Sbjct: 263 PPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPAYTA 322
Query: 219 -PPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGG------VTKWKSDVALNGRQAEA 271
PP L P PP P P PP A H PPG V + + D +++ A
Sbjct: 323 HPPGHRLVPAAPPGPGPRPPG-AESHGCLPATRPPGSDLRESRVQRSRMDSSVS---PAA 378
Query: 272 TRASPPRSPAEPKG---------SALGPNP-----EPHLTFPRSFKVPPPTPVRTSSIPV 317
T A P +P+ P G S+ N EP+ P + P + +
Sbjct: 379 TTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRL 438
Query: 318 QEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLG 377
+ + RK A L LPP P P P CP L+ P + G
Sbjct: 439 GPSAHSSRKPFLGAPAATPHLSLPPG----------PSSPPPPPCPRLLRPPPPPAWLKG 488
Query: 378 QSQSQADERA--------GTPPPAPPLPPPAPP----LPPPAPPL--------PPAAPPL 417
+ A E GT P P PPP P L PPA P PP
Sbjct: 489 PACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPT 548
Query: 418 PCAQKA-------AHPPAGFTKTPKSS--SPALKPKPNPPSPENTASSAPVDWRDPSQME 468
P + + PAG P + ++ P P PPSP P+ +
Sbjct: 549 PTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPP 608
Query: 469 KLRNELAAYLCGSRREDRFLSHRPGPTVA-PQSKEGKKGPRLPEKETLLSLPAKDTPPGV 527
+ GS R P P V+ P++ E GP LS + PPGV
Sbjct: 609 APPSSCHQNTSGSFRR----PESPRPRVSFPKTPEVGPGP----PPGPLSKAPQPVPPGV 660
Query: 528 PEKSLGGSSLTETEAAP---SLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKP 584
E G L + P P+ I D ++ + + E++ +
Sbjct: 661 GELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKE-----EEQQQH 715
Query: 585 SIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSL---QPKAMLGPAI 641
G P P E ++ D A + +TT TT+ + + PA+
Sbjct: 716 EAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPAL 775
Query: 642 PPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLK---ATSGPAIASTATTL 698
PP P PP + P PP PA+ LK+ + K +G A+++ L
Sbjct: 776 PP-PPPLAKFPPPSQ--PQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPL 832
Query: 699 PTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQG---ARSSAA-- 753
PTT Q SG P A+ +Q + S S +++ T G AR A
Sbjct: 833 PTT--QYSPGPPSGATALPPTSAAPS----AQGSPQPSASSSSQFSTSGGPWARERRAGE 886
Query: 754 --FPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLAR---GGAAGPGEPVEVKEPPG 808
P +P P P +S + E++ TL A P +PV+ EP
Sbjct: 887 EPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPAD 946
Query: 809 LPAK---PPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLP 865
+ PPA A+ E +A + + +R QK
Sbjct: 947 SGTERLLPPAQAK---------------EEAGGVAAVSGSCKRRQKEHQ----------- 980
Query: 866 GSLRDHSHQAEASSDSIFH--SQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRD 923
++H A DS+ +G + VPK EK + + + GR+
Sbjct: 981 ---KEHRRHRRACKDSVGRRPREGRAKAKAKVPK-----EKSRRVLGNLDLQSEEIQGRE 1032
Query: 924 AEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNF 983
+L KP P AP P P P + +PPS S ++ EE
Sbjct: 1033 KSRPDLGGASK-AKP-PTAPA----------PPSAPAPSAQPTPPSASVPGKKAREE--- 1077
Query: 984 EVIPPPPEFSNDPEPPAPALQYLGRQSSPPR 1014
P PP S A L+ PP+
Sbjct: 1078 --APGPPGVSR-----ADMLKLRSLSEGPPK 1101
Score = 58.9 bits (141), Expect = 3e-08
Identities = 87/360 (24%), Positives = 122/360 (33%), Gaps = 42/360 (11%)
Query: 60 TVSESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNL 119
T + + TAT + + P L P A+ P P + +S++ G
Sbjct: 756 TTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQK 815
Query: 120 RLYSSVG---DLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTA------ 170
Y G RPG P PP G PP + GSP PS S++
Sbjct: 816 YCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSG 875
Query: 171 ------------PPPPPLLLEPPPPPSMAPP---PPPVLEALSPP-HTLSSPSIPTPPDF 214
P P P+ PPPP PP VLE +S TL + D
Sbjct: 876 GPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATD- 934
Query: 215 IPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRA 274
PA P+ P PPA A G + K + R A +
Sbjct: 935 --PADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKRRQKEHQKEHRRHRRACKD 992
Query: 275 SPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKE-EGATKK 333
S R P E + A P+ +S +V +++ I + +E R + GA+K
Sbjct: 993 SVGRRPREGRAKAKAKVPK-----EKSRRVLGNLDLQSEEI---QGREKSRPDLGGASKA 1044
Query: 334 APSRLPLPPSFHIRPASQVYPDRAPEPDCPG-ELKATAPASPRLGQSQSQADERAGTPPP 392
P P PPS PA P P PG + + AP P + ++ PP
Sbjct: 1045 KPPTAPAPPS---APAPSAQP-TPPSASVPGKKAREEAPGPPGVSRADMLKLRSLSEGPP 1100
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 122 bits (306), Expect = 2e-27
Identities = 155/617 (25%), Positives = 225/617 (36%), Gaps = 122/617 (19%)
Query: 182 PPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPAS 241
P S+ PP P + ++P +T S PS P PP PP PP PPPPP+P+ + P+ S
Sbjct: 601 PYTSLVPPLSPQPKIVTP-YTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGS 659
Query: 242 PHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRS 301
+ + +T+ + N Q PP P S +P + P +
Sbjct: 660 AAPMFVKY---STITRLQ-----NASQHSGALFKPPTPPVMQSQSV-----KPQILVPPN 706
Query: 302 FKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVY----PDRA 357
VPPP P P + A K P PP I + P
Sbjct: 707 GVVPPPPP--PPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPP 764
Query: 358 PEPDCPGELKATAPASPRL-------GQSQSQADERAGTPPPAPPLPP----PAPPLP-- 404
P P P L AP P + ++ + +A P P PP+PP PA P
Sbjct: 765 PPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYI 824
Query: 405 PPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDP 464
PP+PP PP P P PK S KP P+P SP P
Sbjct: 825 PPSPPTPPVPVPPP-------------TLPKQQSFCAKPPPSPLSPV------------P 859
Query: 465 SQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTP 524
S ++++ ++ E + L P VAPQS K + + + + +P+ D P
Sbjct: 860 SVVKQIASQFPPPPTPPAMESQPLKPVPA-NVAPQSPPAVKA-KPKWQPSSIPVPSPDFP 917
Query: 525 PGVPEKSLGGSSLTETEAAPS-LTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAK 583
P PE SSL PS + P P SPTP + ++ SS K K
Sbjct: 918 PPPPE-----SSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGK--K 970
Query: 584 PSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPP 643
P PP P+ +GA+ + +P +L + T + S + + PA PP
Sbjct: 971 P-----PPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPP 1025
Query: 644 K---------------------------------ATPEPAIPPKATLWPATPPKATLGPA 670
K + E PP + +P PP+ L P
Sbjct: 1026 KPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETEL-PL 1084
Query: 671 TPLK---ATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVST 727
P++ SG T+P A P P S++ +K A P +P + +
Sbjct: 1085 PPIEIPAVFSGNTSPKVAVVNPQ--------PQQWSKMSVKK----APPPTRPKRNDSTR 1132
Query: 728 PSQARGEGSPSEATRLP 744
+QA P+ AT +P
Sbjct: 1133 LTQAEISEQPTMATVVP 1149
Score = 121 bits (303), Expect = 5e-27
Identities = 161/605 (26%), Positives = 224/605 (37%), Gaps = 155/605 (25%)
Query: 138 LIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSM----------- 186
L+PP P P P S+P P P PP PPPPP PPPPP +
Sbjct: 605 LVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPP----PPPPPPLPSQSAPSAGSA 660
Query: 187 ------------------------APPPPPVLEALS--------------------PPHT 202
PP PPV+++ S PP T
Sbjct: 661 APMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPT 720
Query: 203 LSS--------PSIPTPPDFIPPAPPLAF------------LAPPPPPVPAPAPP-APAS 241
S P P+ P F P PPL PPPPP+PAP PP AP
Sbjct: 721 PGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPK 780
Query: 242 PHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRS 301
P P TK + V T+A+PP +P P P + FP S
Sbjct: 781 PLVT----IPAPTSTKTVAPV--------VTQAAPP-TPTPPV-----PPAKKQPAFPAS 822
Query: 302 FKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPD 361
+ +PP P T +PV P+++ K PS L PS + ASQ P P
Sbjct: 823 Y-IPPSPP--TPPVPV-PPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAM 878
Query: 362 CPGELKA----TAPASPRLGQSQSQADERAGTPPPAPPLPPPAP------PLPPPAP-PL 410
LK AP SP +++ + + + P P+P PPP P P PPP+P P
Sbjct: 879 ESQPLKPVPANVAPQSPPAVKAKPKW-QPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPA 937
Query: 411 PPAAPP---LPCAQKAAHPPAGFTKTPKSSSP-ALKPKPNPPSPENTASSAPVDWRDPSQ 466
PP PP P K+ P KT K+SSP KP P P + SS+ + +P +
Sbjct: 938 PPPPPPPTASPTPDKSGSPG---KKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKR 994
Query: 467 MEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQ-SKEGKKGPRLP---------EKETLL 516
+ + ++ + + P P P+ K G LP K +L
Sbjct: 995 -PSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVL 1053
Query: 517 SLPAKDTP---PGVPEKSLGGSSLTETE-AAPSLTLPSVDYIPQDSPTPSVRQIRNELEA 572
S KD+ P P S ETE P + +P+V + SP +V
Sbjct: 1054 SGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAV-FSGNTSPKVAV--------- 1103
Query: 573 RLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQ 632
++ ++ +K S+ PP R + D +L++ P + T++P
Sbjct: 1104 -VNPQPQQWSKMSVKKAPPPTRPKRN-------DSTRLTQAEISEQPTMA-TVVPQVPTS 1154
Query: 633 PKAML 637
PK+ L
Sbjct: 1155 PKSSL 1159
Score = 97.1 bits (240), Expect = 9e-20
Identities = 157/654 (24%), Positives = 227/654 (34%), Gaps = 124/654 (18%)
Query: 306 PPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGE 365
P VR+ SI EA ++ + + +R+ RP + + P +P+P
Sbjct: 563 PAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMN----RPYTSLVPPLSPQPKIVTP 618
Query: 366 LKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPP--------- 416
A+ P+ P PPP PP PPP PP PPP PPLP + P
Sbjct: 619 YTASQPSPP--------------LPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMF 664
Query: 417 -----LPCAQKAAHPPAGFTKTPK---SSSPALKPK-----------PNPPSPENTASSA 457
+ Q A+ K P S ++KP+ P PP P T SA
Sbjct: 665 VKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSA 724
Query: 458 PVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLS 517
+ L A + + ++ PT P P + L++
Sbjct: 725 MAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVT 784
Query: 518 LPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSV-----------DYIPQDSPTPSVRQI 566
+PA + V + T+AAP P V YIP PTP V
Sbjct: 785 IPAPTSTKTV--------APVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVP 836
Query: 567 RNELEARLSSAAEKEAKP----------SIGSLPPKPRLEGGRICENGADDDKLSKPVAK 616
L + S A+ P PP P A + + KPV
Sbjct: 837 PPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPP--------TPPAMESQPLKPVPA 888
Query: 617 NLPPQSTTLLPTTSLQPKAMLGPAIPPKATPE-PAIPPKATL-WPATPPKATLGPATPLK 674
N+ PQS P +PK P+ P +P+ P PP+++L +P PP P P
Sbjct: 889 NVAPQSP---PAVKAKPKWQ--PSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPP 943
Query: 675 ATSGPTTPLKATSGPAIASTAT----TLPTTTSQLMAEKDSGPAGQPE--KPASQE-VST 727
T+ PT + G + T++ P T + + K S A PE +P+ VS
Sbjct: 944 PTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSK 1003
Query: 728 PSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMP 787
+ GSPS+ T LP A P K + G +P + + C V+ P
Sbjct: 1004 FTPPAESGSPSKET-LPPPAAPPK---PGKLNLSGVNLPGVLQQGC--------VSAKAP 1051
Query: 788 TLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQ 847
L+ G VE PP PP P EL P+ V G+ +
Sbjct: 1052 VLS---GRGKDSVVEFPSPPSDSDFPP--PPPETELPLPPIEIPAVFSGNTSPKVAVVNP 1106
Query: 848 RAQKGRSVGAALGRSSLPGSLRDHSH--QAEASSDSIFHSQGTPNSFTVVPKLP 899
+ Q+ + D + QAE S P TVVP++P
Sbjct: 1107 QPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQ--------PTMATVVPQVP 1152
Score = 60.5 bits (145), Expect = 9e-09
Identities = 85/345 (24%), Positives = 115/345 (33%), Gaps = 89/345 (25%)
Query: 139 IPPPPPGPAPGPPQD--ISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAP-------- 188
IP P P P PP+ + PP SP+P+P PPPPP P P S +P
Sbjct: 909 IPVPSPDFPPPPPESSLVFPPPPPSPVPAP----PPPPPPTASPTPDKSGSPGKKTSKTS 964
Query: 189 -----PPPPVLEALSPPHTLSSPSIPTP---------PDFIPPA---PPLAFLAPPPPPV 231
PPP + S + S P P F PPA P PPP
Sbjct: 965 SPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPP--- 1021
Query: 232 PAPAPPAPASPHTVGTRL---FPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSAL 288
APP P + G L G V+ ++ G+ + SPP P
Sbjct: 1022 --AAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPE 1079
Query: 289 GPNPEPHLTFPRSFK--------VPPPTPVRTSSIPVQEA--------QEAPRKEEGATK 332
P P + P F V P P + S + V++A ++ R +
Sbjct: 1080 TELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEIS 1139
Query: 333 KAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASP-----RLGQSQSQADERA 387
+ P+ + P P S + + +P +L T L S+A+ A
Sbjct: 1140 EQPTMATVVPQVPTSPKSSL----SVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTA 1195
Query: 388 GTPPPAPPLPPPAPPL-----------------------PPPAPP 409
A LPPP P L PPPAPP
Sbjct: 1196 TMDDMA--LPPPPPELLSDQQKAGYGGSHISGYATLRRGPPPAPP 1238
Score = 53.9 bits (128), Expect = 9e-07
Identities = 126/565 (22%), Positives = 177/565 (31%), Gaps = 77/565 (13%)
Query: 602 ENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPAT 661
+ G ++ SK +++ T+L+P S QPK + TP A P L P
Sbjct: 582 KRGTQLEESSKARMESMNRPYTSLVPPLSPQPKIV---------TPYTASQPSPPLPPPP 632
Query: 662 PPKATLGPATPLKATSGPTTPLKATSGPAIASTATTL---PTTTSQLMAEKDSGPAGQPE 718
PP P P P PL + S P+ S A T T A + SG +P
Sbjct: 633 PP-----PPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPP 687
Query: 719 KPA---SQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKP---- 771
P SQ V G P SA K +P +P P
Sbjct: 688 TPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPL 747
Query: 772 HCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQ-PTDELLRHPVTG 830
HQ +VA P P P+ PP P KP + PT PV
Sbjct: 748 KIHQVQHITQVAPPTPP--------PPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVT 799
Query: 831 EVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPN 890
+ + A +Q A + + +P Q F ++ P+
Sbjct: 800 QAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQS------FCAKPPPS 853
Query: 891 SFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVA 950
+ VP + K+ P P P + + +P PV VA
Sbjct: 854 PLSPVPSVVKQIASQFP-----PPPTPPAM----------------ESQPLKPVP-ANVA 891
Query: 951 PSNLPQGHPLPK-SFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQ 1009
P + P PK SS P PS E + PPPP P PP P
Sbjct: 892 PQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPT----AS 947
Query: 1010 SSPPRNNYSDLRQLPNAGPGA--PPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLY 1067
+P ++ + + PG PP R + +GA E SL+ K
Sbjct: 948 PTPDKSGSPGKKTSKTSSPGGKKPPPTP-QRNSSIKSSSGAEHPEPKRPSVDSLVSKFT- 1005
Query: 1068 VGEPHRGPGLPHGGTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPGGLHAPRLSLEGAAR 1127
P G + P P+PG + VN G G + A L G +
Sbjct: 1006 -------PPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGK 1058
Query: 1128 GAAEAKHKAPGSADYGFAPAAGRSP 1152
+ P +D+ P P
Sbjct: 1059 DSVVEFPSPPSDSDFPPPPPETELP 1083
Score = 35.4 bits (80), Expect = 0.33
Identities = 47/196 (23%), Positives = 71/196 (36%), Gaps = 51/196 (26%)
Query: 854 SVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIP 913
S+ + SS+P S +HS+Q++ S S G S ++V + EA K
Sbjct: 533 SIKSGSSSSSIPESQSNHSNQSD-SGVSDTQPAGHVRSQSIVSSVFSEAWKR-------- 583
Query: 914 NKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNK 973
G E + +R + +P + + P PQ + +S PSP
Sbjct: 584 -------GTQLEESSKARMESMNRP-------YTSLVPPLSPQPKIVTPYTASQPSPP-- 627
Query: 974 REEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNN-------YSDLRQLPNA 1026
+ PPPP P PP P L QS+P + YS + +L NA
Sbjct: 628 -----------LPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNA 676
Query: 1027 G--------PGAPPAL 1034
P PP +
Sbjct: 677 SQHSGALFKPPTPPVM 692
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 119 bits (299), Expect = 1e-26
Identities = 195/819 (23%), Positives = 282/819 (34%), Gaps = 126/819 (15%)
Query: 21 TTPSTSLYATNPPWIFTQEAPEEGTG-GFDGIYYGDNRFNTVSESGTATLKARPRVRPLL 79
T+ TSL + T+E DG + T S T+ P + L
Sbjct: 136 TSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA 195
Query: 80 TFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNLRLYSSVGDLRPGQYGQDLLI 139
P G A+ TP P KE T+ + S+
Sbjct: 196 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA--------------- 240
Query: 140 PPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPP-----PPVL 194
P P PAP + P P+P +T P P EP P + P P P
Sbjct: 241 PTTPKEPAPTTTKSAPTTPKE---PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTT 297
Query: 195 EALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASP-HTVGTRLFPPG 253
P T P+ TP + P P P P P PAP +P T P
Sbjct: 298 PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 357
Query: 254 GVTKWKSDVALNGRQAEATRASP-PRSPAEPKGSALGPNP----EPHLTFPRSFKVPP-- 306
T + A T P P +P EP + P EP T +S P
Sbjct: 358 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 417
Query: 307 PTPVRTS----SIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDC 362
P+P T + P + A P+K T K P+ P P ++ P+
Sbjct: 418 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA--PTTPKEPAPTTTKKPAPTTPKEPA 475
Query: 363 PGELKATAPASPRLGQSQSQADERAGTPP--PAPPLP----PPAPPLPPPAPPLPPAAPP 416
P K TAP +P+ + + ++ A T P PAP P P P P P P P AP
Sbjct: 476 PTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEP-APT 533
Query: 417 LPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTA-----SSAPVDWRDPSQMEKLR 471
P A P TPK +P +P P +P+ TA +AP ++P+ +
Sbjct: 534 TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKK 593
Query: 472 ---NELAAYLCGSRREDRFLSHRPGPT----VAPQSKEGKKGPRLPEK----------ET 514
ELA ++ +P PT AP + + + P P++ T
Sbjct: 594 PAPKELAP--TTTKEPTSTTCDKPAPTTPKGTAPTTPK-EPAPTTPKEPAPTTPKGTAPT 650
Query: 515 LLSLPAKDTPPGVPEKSL------GGSSLTETEAAPSL---TLPSVDYIP---------- 555
L PA TP K L G +S T + AP+ T P+ P
Sbjct: 651 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 710
Query: 556 --QDSPTPSVRQIRNELEARLSSAAEK---EAKPSIGSLPPKPRLEGGRICENGADDDK- 609
++P P+ ++ + + K E+ P + + P LE E G K
Sbjct: 711 TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP-KEPGVPTTKT 769
Query: 610 --LSKPVAKNLPPQST------TLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPAT 661
+KP T T TT+ PK A + T E I T +T
Sbjct: 770 PAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTST 829
Query: 662 PPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPA 721
+ T TP K T+ TT T P + +T T+ TT E+ + P ++
Sbjct: 830 TTQDT----TPFKITTLKTT----TLAPKVTTTKKTITTTEIMNKPEETAKP---KDRAT 878
Query: 722 SQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSP 760
+ + +TP + P++A + PT + PKT P
Sbjct: 879 NSKATTPKPQK----PTKAPKKPTSTKK------PKTMP 907
Score = 119 bits (298), Expect = 2e-26
Identities = 176/711 (24%), Positives = 246/711 (34%), Gaps = 121/711 (17%)
Query: 140 PPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPP------PSMAPPPPPV 193
P P PAP P+ EP +P P+T P P EP P P+ P P
Sbjct: 311 PTTPKEPAPTTPK---EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 367
Query: 194 LEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAP-----APPAPASPHTVGTR 248
P T PS TP + PAP AP PAP AP P P T+
Sbjct: 368 TPKEPAPTTTKEPSPTTPKE---PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 424
Query: 249 LFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPT 308
P T + + A T P +P PK A +P T P+ + P T
Sbjct: 425 --EPAPTTPKEPAPTTPKKPAPTTPKEP--APTTPKEPAPTTTKKPAPTTPK--EPAPTT 478
Query: 309 PVRTS-SIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPD-RAPEPDCPGEL 366
P T+ + P + P K T + P+ P P + P + P PE P
Sbjct: 479 PKETAPTTPKKLTPTTPEKLAPTTPEKPA--PTTPE-ELAPTTPEEPTPTTPEEPAPTTP 535
Query: 367 KATAPASPRLGQSQSQADERAGTPP-PAPPLPPPAPPLPP----------PAPPLPPAAP 415
KA AP +P+ + + TP PAP P P P PAP P
Sbjct: 536 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA 595
Query: 416 PLPCAQKAAHPPAGFT------KTPKSSSPALKPKPNP-----PSPENTASSAPVDWRDP 464
P A P T TPK ++P +P P P+P +AP ++P
Sbjct: 596 PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP 655
Query: 465 SQMEKLR---NELAAYLCGSRREDRFLSHRPGPTV----APQSKEGKKGPRLPEKETLLS 517
+ + ELA ++ S +P PT AP + + + P P+K
Sbjct: 656 APTTPKKPAPKELAPTT--TKGPTSTTSDKPAPTTPKETAPTTPK-EPAPTTPKK----- 707
Query: 518 LPAKDTPPGVPEKSLGGSSLTET-----------EAAPSL----TLPSVDYIPQDSPTPS 562
PA TP P + S+ T T E+ P L T +++ P++ P+
Sbjct: 708 -PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPT 766
Query: 563 VRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKL--SKPVAKNLPP 620
+ ++A +K + + + P E +K SK A
Sbjct: 767 TKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQV 826
Query: 621 QSTTLLPTTSLQPKAMLGPAIPPKAT--------------PEPAIPPK--ATLWPATPPK 664
STT TT + + + PK T PE PK AT AT PK
Sbjct: 827 TSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPK 886
Query: 665 ATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQE 724
P P KA PT+ K + P + TT PT + P + + Q
Sbjct: 887 ----PQKPTKAPKKPTSTKKPKTMPRVRKPKTT-PTPRKMTSTMPELNPTSRIAEAMLQT 941
Query: 725 VSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGG--GEVP-CLYKPH 772
+ P+Q T ++ P GG GE P L +PH
Sbjct: 942 TTRPNQ--------------TPNSKLVEVNPKSEDAGGAEGETPHMLLRPH 978
Score = 114 bits (285), Expect = 6e-25
Identities = 188/762 (24%), Positives = 261/762 (34%), Gaps = 156/762 (20%)
Query: 164 PSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAF 223
P+P + P L P P P P P T + TP + PAP
Sbjct: 197 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKE---PAPTTTK 253
Query: 224 LAPPPPPVPAPAP---PAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSP 280
AP P PAP PAP +P T KS A T P +P
Sbjct: 254 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP--AP 311
Query: 281 AEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPL 340
PK A EP T P+ + P T + P + A AP+K T K P+
Sbjct: 312 TTPKEPAPTTPKEPTPTTPK--EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA---- 365
Query: 341 PPSFHIRPASQVYPDRAPEPDCPGE-LKATAPASPRLGQSQSQADERAGTPPPAPPLPP- 398
P+ PA + P P P E T ++P + + ++ P P P
Sbjct: 366 -PTTPKEPAPTT--TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 422
Query: 399 ---PAPPLPP-PAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTA 454
PAP P PAP P P P K P TPK +P KP P +P+ A
Sbjct: 423 TKEPAPTTPKEPAPTTPKK--PAPTTPKEPAPT-----TPKEPAPTTTKKPAPTTPKEPA 475
Query: 455 SSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKET 514
+ P + P+ +KL P + E K P PEK
Sbjct: 476 PTTPKETA-PTTPKKL--------------------------TPTTPE-KLAPTTPEK-- 505
Query: 515 LLSLPAKDTP----PGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNEL 570
PA TP P PE+ + T E AP+ + P++ P P+
Sbjct: 506 ----PAPTTPEELAPTTPEEP---TPTTPEEPAPTTPKAAAPNTPKE-PAPTT------- 550
Query: 571 EARLSSAAEKEAKPSIGSLP-PKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTT 629
KE P+ P P E G L +P PTT
Sbjct: 551 --------PKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPA------------PTT 590
Query: 630 SLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGP 689
PK + P T EP P TP K T P TP + PTTP + P
Sbjct: 591 ---PKKPAPKELAPTTTKEPTSTTCDKPAPTTP-KGT-APTTPKEPA--PTTPKE----P 639
Query: 690 AIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGAR 749
A + T PTT K+ P P+KPA +E++ P+ +G S + PT
Sbjct: 640 APTTPKGTAPTTL------KEPAPT-TPKKPAPKELA-PTTTKGPTSTTSDKPAPTTPKE 691
Query: 750 SSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGL 809
++ P + +P + P P + S V PT + EP + + P
Sbjct: 692 TAPTTPKEPAPTTPKKPAPTTPETPPPTTSE---VSTPTTTK-------EPTTIHKSPD- 740
Query: 810 PAKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLR 869
+ P SA+PT + L + E G P AA + + + +
Sbjct: 741 ESTPELSAEPTPKALENSPK----EPGVPTTKTPAAT--------------KPEMTTTAK 782
Query: 870 DHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTE 911
D + + + + TP + T PK+ KE + TTE
Sbjct: 783 DKTTERDLRT--------TPETTTAAPKMTKETATTTEKTTE 816
Score = 60.8 bits (146), Expect = 7e-09
Identities = 93/427 (21%), Positives = 137/427 (32%), Gaps = 53/427 (12%)
Query: 596 EGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKA 655
+G + + + K AK+L P S L T GPA+ P P P +
Sbjct: 165 DGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE- 223
Query: 656 TLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAG 715
P T TP S PTTP + PA +T + PTT + PA
Sbjct: 224 ------PASTTPKEPTPTTIKSAPTTPKE----PA-PTTTKSAPTTPKEPAPTTTKEPAP 272
Query: 716 Q-PEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCH 774
P++PA P+ P+ PT + P K +P + P P
Sbjct: 273 TTPKEPAPTTTKEPA-------PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 325
Query: 775 QSSLSREVAVVMPTLARGGAAGPGEPVEV--KEPPGLPAKPPASAQPTDELLRHPVTGEV 832
+ +E A PT P EP K+P K PA P + P T +
Sbjct: 326 TPTTPKEPA---PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA---PTTTKE 379
Query: 833 VERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNS- 891
+P + A A S P + ++ S + P +
Sbjct: 380 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP 439
Query: 892 --------FTVVPKLPKE-----AEKDSPLTTEIPNKWGPRLGRDAEGTELS----RRHN 934
P PKE +K +P T + P P+ +L+ +
Sbjct: 440 KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA 499
Query: 935 WTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSN 994
T PE AP E +AP+ + P +P +P +E P P
Sbjct: 500 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE-------PAPTTPK 552
Query: 995 DPEPPAP 1001
+P P P
Sbjct: 553 EPAPTTP 559
Score = 41.2 bits (95), Expect = 0.006
Identities = 96/465 (20%), Positives = 146/465 (31%), Gaps = 90/465 (19%)
Query: 591 PKPRL--EGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPE 648
PKP + E G +NG D K++ P STT S PK I P+
Sbjct: 80 PKPPVVDEAGSGLDNG--DFKVTTP------DTSTTQHNKVSTSPKITTAKPINPR---- 127
Query: 649 PAIPPKATLWPATPPKATLGPATPLKA-------TSGPTTPLKATSGPAIASTATTLPTT 701
P+ PP + T L T TT K TS T + T
Sbjct: 128 ----------PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQ 177
Query: 702 TSQLMAEKDSGPAGQ----------------------------PEKPASQEVSTPSQARG 733
+ + + KD P + P++PAS P+
Sbjct: 178 SIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI 237
Query: 734 EGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGG 793
+ +P+ +S+ P + +P + P P + ++E A PT +
Sbjct: 238 KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA---PTTTKSA 294
Query: 794 AAGPGEPVEV---KEPPGLPAKP----PASAQPTDELLRHPVTGEVVERGSPMALLLAAR 846
P EP K P P +P P PT P T E A +
Sbjct: 295 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPK 354
Query: 847 QRA-QKGRSVGAALGRSSLPGSLRDHS-------HQAEASSDSIFHSQGTPNSFTVVPKL 898
+ A + + P + ++ S S + P + P
Sbjct: 355 KPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTT 414
Query: 899 PKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGH 958
PKE SP TT+ P P+ ++ T P+ AP + AP+ +
Sbjct: 415 PKE---PSPTTTKEPAPTTPK----EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 467
Query: 959 PLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPE--FSNDPEPPAP 1001
P +P +P +E ++ P PE PE PAP
Sbjct: 468 PTTPKEPAPTTP----KETAPTTPKKLTPTTPEKLAPTTPEKPAP 508
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 119 bits (299), Expect = 1e-26
Identities = 195/819 (23%), Positives = 282/819 (34%), Gaps = 126/819 (15%)
Query: 21 TTPSTSLYATNPPWIFTQEAPEEGTG-GFDGIYYGDNRFNTVSESGTATLKARPRVRPLL 79
T+ TSL + T+E DG + T S T+ P + L
Sbjct: 177 TSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA 236
Query: 80 TFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNLRLYSSVGDLRPGQYGQDLLI 139
P G A+ TP P KE T+ + S+
Sbjct: 237 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA--------------- 281
Query: 140 PPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPP-----PPVL 194
P P PAP + P P+P +T P P EP P + P P P
Sbjct: 282 PTTPKEPAPTTTKSAPTTPKE---PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTT 338
Query: 195 EALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASP-HTVGTRLFPPG 253
P T P+ TP + P P P P P PAP +P T P
Sbjct: 339 PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 398
Query: 254 GVTKWKSDVALNGRQAEATRASP-PRSPAEPKGSALGPNP----EPHLTFPRSFKVPP-- 306
T + A T P P +P EP + P EP T +S P
Sbjct: 399 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 458
Query: 307 PTPVRTS----SIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDC 362
P+P T + P + A P+K T K P+ P P ++ P+
Sbjct: 459 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA--PTTPKEPAPTTTKKPAPTTPKEPA 516
Query: 363 PGELKATAPASPRLGQSQSQADERAGTPP--PAPPLP----PPAPPLPPPAPPLPPAAPP 416
P K TAP +P+ + + ++ A T P PAP P P P P P P P AP
Sbjct: 517 PTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEP-APT 574
Query: 417 LPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTA-----SSAPVDWRDPSQMEKLR 471
P A P TPK +P +P P +P+ TA +AP ++P+ +
Sbjct: 575 TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKK 634
Query: 472 ---NELAAYLCGSRREDRFLSHRPGPT----VAPQSKEGKKGPRLPEK----------ET 514
ELA ++ +P PT AP + + + P P++ T
Sbjct: 635 PAPKELAP--TTTKEPTSTTCDKPAPTTPKGTAPTTPK-EPAPTTPKEPAPTTPKGTAPT 691
Query: 515 LLSLPAKDTPPGVPEKSL------GGSSLTETEAAPSL---TLPSVDYIP---------- 555
L PA TP K L G +S T + AP+ T P+ P
Sbjct: 692 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 751
Query: 556 --QDSPTPSVRQIRNELEARLSSAAEK---EAKPSIGSLPPKPRLEGGRICENGADDDK- 609
++P P+ ++ + + K E+ P + + P LE E G K
Sbjct: 752 TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP-KEPGVPTTKT 810
Query: 610 --LSKPVAKNLPPQST------TLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPAT 661
+KP T T TT+ PK A + T E I T +T
Sbjct: 811 PAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTST 870
Query: 662 PPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPA 721
+ T TP K T+ TT T P + +T T+ TT E+ + P ++
Sbjct: 871 TTQDT----TPFKITTLKTT----TLAPKVTTTKKTITTTEIMNKPEETAKP---KDRAT 919
Query: 722 SQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSP 760
+ + +TP + P++A + PT + PKT P
Sbjct: 920 NSKATTPKPQK----PTKAPKKPTSTKK------PKTMP 948
Score = 119 bits (298), Expect = 2e-26
Identities = 176/711 (24%), Positives = 246/711 (34%), Gaps = 121/711 (17%)
Query: 140 PPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPP------PSMAPPPPPV 193
P P PAP P+ EP +P P+T P P EP P P+ P P
Sbjct: 352 PTTPKEPAPTTPK---EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 408
Query: 194 LEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAP-----APPAPASPHTVGTR 248
P T PS TP + PAP AP PAP AP P P T+
Sbjct: 409 TPKEPAPTTTKEPSPTTPKE---PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 465
Query: 249 LFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPT 308
P T + + A T P +P PK A +P T P+ + P T
Sbjct: 466 --EPAPTTPKEPAPTTPKKPAPTTPKEP--APTTPKEPAPTTTKKPAPTTPK--EPAPTT 519
Query: 309 PVRTS-SIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPD-RAPEPDCPGEL 366
P T+ + P + P K T + P+ P P + P + P PE P
Sbjct: 520 PKETAPTTPKKLTPTTPEKLAPTTPEKPA--PTTPE-ELAPTTPEEPTPTTPEEPAPTTP 576
Query: 367 KATAPASPRLGQSQSQADERAGTPP-PAPPLPPPAPPLPP----------PAPPLPPAAP 415
KA AP +P+ + + TP PAP P P P PAP P
Sbjct: 577 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA 636
Query: 416 PLPCAQKAAHPPAGFT------KTPKSSSPALKPKPNP-----PSPENTASSAPVDWRDP 464
P A P T TPK ++P +P P P+P +AP ++P
Sbjct: 637 PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP 696
Query: 465 SQMEKLR---NELAAYLCGSRREDRFLSHRPGPTV----APQSKEGKKGPRLPEKETLLS 517
+ + ELA ++ S +P PT AP + + + P P+K
Sbjct: 697 APTTPKKPAPKELAPTT--TKGPTSTTSDKPAPTTPKETAPTTPK-EPAPTTPKK----- 748
Query: 518 LPAKDTPPGVPEKSLGGSSLTET-----------EAAPSL----TLPSVDYIPQDSPTPS 562
PA TP P + S+ T T E+ P L T +++ P++ P+
Sbjct: 749 -PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPT 807
Query: 563 VRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKL--SKPVAKNLPP 620
+ ++A +K + + + P E +K SK A
Sbjct: 808 TKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQV 867
Query: 621 QSTTLLPTTSLQPKAMLGPAIPPKAT--------------PEPAIPPK--ATLWPATPPK 664
STT TT + + + PK T PE PK AT AT PK
Sbjct: 868 TSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPK 927
Query: 665 ATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQE 724
P P KA PT+ K + P + TT PT + P + + Q
Sbjct: 928 ----PQKPTKAPKKPTSTKKPKTMPRVRKPKTT-PTPRKMTSTMPELNPTSRIAEAMLQT 982
Query: 725 VSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGG--GEVP-CLYKPH 772
+ P+Q T ++ P GG GE P L +PH
Sbjct: 983 TTRPNQ--------------TPNSKLVEVNPKSEDAGGAEGETPHMLLRPH 1019
Score = 114 bits (285), Expect = 6e-25
Identities = 188/762 (24%), Positives = 261/762 (34%), Gaps = 156/762 (20%)
Query: 164 PSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAF 223
P+P + P L P P P P P T + TP + PAP
Sbjct: 238 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKE---PAPTTTK 294
Query: 224 LAPPPPPVPAPAP---PAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSP 280
AP P PAP PAP +P T KS A T P +P
Sbjct: 295 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP--AP 352
Query: 281 AEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPL 340
PK A EP T P+ + P T + P + A AP+K T K P+
Sbjct: 353 TTPKEPAPTTPKEPTPTTPK--EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA---- 406
Query: 341 PPSFHIRPASQVYPDRAPEPDCPGE-LKATAPASPRLGQSQSQADERAGTPPPAPPLPP- 398
P+ PA + P P P E T ++P + + ++ P P P
Sbjct: 407 -PTTPKEPAPTT--TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 463
Query: 399 ---PAPPLPP-PAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTA 454
PAP P PAP P P P K P TPK +P KP P +P+ A
Sbjct: 464 TKEPAPTTPKEPAPTTPKK--PAPTTPKEPAPT-----TPKEPAPTTTKKPAPTTPKEPA 516
Query: 455 SSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKET 514
+ P + P+ +KL P + E K P PEK
Sbjct: 517 PTTPKETA-PTTPKKL--------------------------TPTTPE-KLAPTTPEK-- 546
Query: 515 LLSLPAKDTP----PGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNEL 570
PA TP P PE+ + T E AP+ + P++ P P+
Sbjct: 547 ----PAPTTPEELAPTTPEEP---TPTTPEEPAPTTPKAAAPNTPKE-PAPTT------- 591
Query: 571 EARLSSAAEKEAKPSIGSLP-PKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTT 629
KE P+ P P E G L +P PTT
Sbjct: 592 --------PKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPA------------PTT 631
Query: 630 SLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGP 689
PK + P T EP P TP K T P TP + PTTP + P
Sbjct: 632 ---PKKPAPKELAPTTTKEPTSTTCDKPAPTTP-KGT-APTTPKEPA--PTTPKE----P 680
Query: 690 AIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGAR 749
A + T PTT K+ P P+KPA +E++ P+ +G S + PT
Sbjct: 681 APTTPKGTAPTTL------KEPAPT-TPKKPAPKELA-PTTTKGPTSTTSDKPAPTTPKE 732
Query: 750 SSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGL 809
++ P + +P + P P + S V PT + EP + + P
Sbjct: 733 TAPTTPKEPAPTTPKKPAPTTPETPPPTTSE---VSTPTTTK-------EPTTIHKSPD- 781
Query: 810 PAKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLR 869
+ P SA+PT + L + E G P AA + + + +
Sbjct: 782 ESTPELSAEPTPKALENSPK----EPGVPTTKTPAAT--------------KPEMTTTAK 823
Query: 870 DHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTE 911
D + + + + TP + T PK+ KE + TTE
Sbjct: 824 DKTTERDLRT--------TPETTTAAPKMTKETATTTEKTTE 857
Score = 60.8 bits (146), Expect = 7e-09
Identities = 93/427 (21%), Positives = 137/427 (32%), Gaps = 53/427 (12%)
Query: 596 EGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKA 655
+G + + + K AK+L P S L T GPA+ P P P +
Sbjct: 206 DGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE- 264
Query: 656 TLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAG 715
P T TP S PTTP + PA +T + PTT + PA
Sbjct: 265 ------PASTTPKEPTPTTIKSAPTTPKE----PA-PTTTKSAPTTPKEPAPTTTKEPAP 313
Query: 716 Q-PEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCH 774
P++PA P+ P+ PT + P K +P + P P
Sbjct: 314 TTPKEPAPTTTKEPA-------PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 366
Query: 775 QSSLSREVAVVMPTLARGGAAGPGEPVEV--KEPPGLPAKPPASAQPTDELLRHPVTGEV 832
+ +E A PT P EP K+P K PA P + P T +
Sbjct: 367 TPTTPKEPA---PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA---PTTTKE 420
Query: 833 VERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNS- 891
+P + A A S P + ++ S + P +
Sbjct: 421 PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTP 480
Query: 892 --------FTVVPKLPKE-----AEKDSPLTTEIPNKWGPRLGRDAEGTELS----RRHN 934
P PKE +K +P T + P P+ +L+ +
Sbjct: 481 KKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA 540
Query: 935 WTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSN 994
T PE AP E +AP+ + P +P +P +E P P
Sbjct: 541 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE-------PAPTTPK 593
Query: 995 DPEPPAP 1001
+P P P
Sbjct: 594 EPAPTTP 600
Score = 41.2 bits (95), Expect = 0.006
Identities = 96/465 (20%), Positives = 146/465 (31%), Gaps = 90/465 (19%)
Query: 591 PKPRL--EGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPE 648
PKP + E G +NG D K++ P STT S PK I P+
Sbjct: 121 PKPPVVDEAGSGLDNG--DFKVTTP------DTSTTQHNKVSTSPKITTAKPINPR---- 168
Query: 649 PAIPPKATLWPATPPKATLGPATPLKA-------TSGPTTPLKATSGPAIASTATTLPTT 701
P+ PP + T L T TT K TS T + T
Sbjct: 169 ----------PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQ 218
Query: 702 TSQLMAEKDSGPAGQ----------------------------PEKPASQEVSTPSQARG 733
+ + + KD P + P++PAS P+
Sbjct: 219 SIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI 278
Query: 734 EGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGG 793
+ +P+ +S+ P + +P + P P + ++E A PT +
Sbjct: 279 KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA---PTTTKSA 335
Query: 794 AAGPGEPVEV---KEPPGLPAKP----PASAQPTDELLRHPVTGEVVERGSPMALLLAAR 846
P EP K P P +P P PT P T E A +
Sbjct: 336 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPK 395
Query: 847 QRA-QKGRSVGAALGRSSLPGSLRDHS-------HQAEASSDSIFHSQGTPNSFTVVPKL 898
+ A + + P + ++ S S + P + P
Sbjct: 396 KPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTT 455
Query: 899 PKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGH 958
PKE SP TT+ P P+ ++ T P+ AP + AP+ +
Sbjct: 456 PKE---PSPTTTKEPAPTTPK----EPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPA 508
Query: 959 PLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPE--FSNDPEPPAP 1001
P +P +P +E ++ P PE PE PAP
Sbjct: 509 PTTPKEPAPTTP----KETAPTTPKKLTPTTPEKLAPTTPEKPAP 549
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 119 bits (299), Expect = 1e-26
Identities = 195/819 (23%), Positives = 282/819 (34%), Gaps = 126/819 (15%)
Query: 21 TTPSTSLYATNPPWIFTQEAPEEGTG-GFDGIYYGDNRFNTVSESGTATLKARPRVRPLL 79
T+ TSL + T+E DG + T S T+ P + L
Sbjct: 229 TSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA 288
Query: 80 TFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNLRLYSSVGDLRPGQYGQDLLI 139
P G A+ TP P KE T+ + S+
Sbjct: 289 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA--------------- 333
Query: 140 PPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPP-----PPVL 194
P P PAP + P P+P +T P P EP P + P P P
Sbjct: 334 PTTPKEPAPTTTKSAPTTPKE---PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTT 390
Query: 195 EALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASP-HTVGTRLFPPG 253
P T P+ TP + P P P P P PAP +P T P
Sbjct: 391 PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 450
Query: 254 GVTKWKSDVALNGRQAEATRASP-PRSPAEPKGSALGPNP----EPHLTFPRSFKVPP-- 306
T + A T P P +P EP + P EP T +S P
Sbjct: 451 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 510
Query: 307 PTPVRTS----SIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDC 362
P+P T + P + A P+K T K P+ P P ++ P+
Sbjct: 511 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA--PTTPKEPAPTTTKKPAPTTPKEPA 568
Query: 363 PGELKATAPASPRLGQSQSQADERAGTPP--PAPPLP----PPAPPLPPPAPPLPPAAPP 416
P K TAP +P+ + + ++ A T P PAP P P P P P P P AP
Sbjct: 569 PTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEP-APT 626
Query: 417 LPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTA-----SSAPVDWRDPSQMEKLR 471
P A P TPK +P +P P +P+ TA +AP ++P+ +
Sbjct: 627 TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKK 686
Query: 472 ---NELAAYLCGSRREDRFLSHRPGPT----VAPQSKEGKKGPRLPEK----------ET 514
ELA ++ +P PT AP + + + P P++ T
Sbjct: 687 PAPKELAP--TTTKEPTSTTCDKPAPTTPKGTAPTTPK-EPAPTTPKEPAPTTPKGTAPT 743
Query: 515 LLSLPAKDTPPGVPEKSL------GGSSLTETEAAPSL---TLPSVDYIP---------- 555
L PA TP K L G +S T + AP+ T P+ P
Sbjct: 744 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 803
Query: 556 --QDSPTPSVRQIRNELEARLSSAAEK---EAKPSIGSLPPKPRLEGGRICENGADDDK- 609
++P P+ ++ + + K E+ P + + P LE E G K
Sbjct: 804 TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP-KEPGVPTTKT 862
Query: 610 --LSKPVAKNLPPQST------TLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPAT 661
+KP T T TT+ PK A + T E I T +T
Sbjct: 863 PAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTST 922
Query: 662 PPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPA 721
+ T TP K T+ TT T P + +T T+ TT E+ + P ++
Sbjct: 923 TTQDT----TPFKITTLKTT----TLAPKVTTTKKTITTTEIMNKPEETAKP---KDRAT 971
Query: 722 SQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSP 760
+ + +TP + P++A + PT + PKT P
Sbjct: 972 NSKATTPKPQK----PTKAPKKPTSTKK------PKTMP 1000
Score = 119 bits (298), Expect = 2e-26
Identities = 176/711 (24%), Positives = 246/711 (34%), Gaps = 121/711 (17%)
Query: 140 PPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPP------PSMAPPPPPV 193
P P PAP P+ EP +P P+T P P EP P P+ P P
Sbjct: 404 PTTPKEPAPTTPK---EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 460
Query: 194 LEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAP-----APPAPASPHTVGTR 248
P T PS TP + PAP AP PAP AP P P T+
Sbjct: 461 TPKEPAPTTTKEPSPTTPKE---PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 517
Query: 249 LFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPT 308
P T + + A T P +P PK A +P T P+ + P T
Sbjct: 518 --EPAPTTPKEPAPTTPKKPAPTTPKEP--APTTPKEPAPTTTKKPAPTTPK--EPAPTT 571
Query: 309 PVRTS-SIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPD-RAPEPDCPGEL 366
P T+ + P + P K T + P+ P P + P + P PE P
Sbjct: 572 PKETAPTTPKKLTPTTPEKLAPTTPEKPA--PTTPE-ELAPTTPEEPTPTTPEEPAPTTP 628
Query: 367 KATAPASPRLGQSQSQADERAGTPP-PAPPLPPPAPPLPP----------PAPPLPPAAP 415
KA AP +P+ + + TP PAP P P P PAP P
Sbjct: 629 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA 688
Query: 416 PLPCAQKAAHPPAGFT------KTPKSSSPALKPKPNP-----PSPENTASSAPVDWRDP 464
P A P T TPK ++P +P P P+P +AP ++P
Sbjct: 689 PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP 748
Query: 465 SQMEKLR---NELAAYLCGSRREDRFLSHRPGPTV----APQSKEGKKGPRLPEKETLLS 517
+ + ELA ++ S +P PT AP + + + P P+K
Sbjct: 749 APTTPKKPAPKELAPTT--TKGPTSTTSDKPAPTTPKETAPTTPK-EPAPTTPKK----- 800
Query: 518 LPAKDTPPGVPEKSLGGSSLTET-----------EAAPSL----TLPSVDYIPQDSPTPS 562
PA TP P + S+ T T E+ P L T +++ P++ P+
Sbjct: 801 -PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPT 859
Query: 563 VRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKL--SKPVAKNLPP 620
+ ++A +K + + + P E +K SK A
Sbjct: 860 TKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQV 919
Query: 621 QSTTLLPTTSLQPKAMLGPAIPPKAT--------------PEPAIPPK--ATLWPATPPK 664
STT TT + + + PK T PE PK AT AT PK
Sbjct: 920 TSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPK 979
Query: 665 ATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQE 724
P P KA PT+ K + P + TT PT + P + + Q
Sbjct: 980 ----PQKPTKAPKKPTSTKKPKTMPRVRKPKTT-PTPRKMTSTMPELNPTSRIAEAMLQT 1034
Query: 725 VSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGG--GEVP-CLYKPH 772
+ P+Q T ++ P GG GE P L +PH
Sbjct: 1035 TTRPNQ--------------TPNSKLVEVNPKSEDAGGAEGETPHMLLRPH 1071
Score = 114 bits (285), Expect = 6e-25
Identities = 188/762 (24%), Positives = 261/762 (34%), Gaps = 156/762 (20%)
Query: 164 PSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAF 223
P+P + P L P P P P P T + TP + PAP
Sbjct: 290 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKE---PAPTTTK 346
Query: 224 LAPPPPPVPAPAP---PAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSP 280
AP P PAP PAP +P T KS A T P +P
Sbjct: 347 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP--AP 404
Query: 281 AEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPL 340
PK A EP T P+ + P T + P + A AP+K T K P+
Sbjct: 405 TTPKEPAPTTPKEPTPTTPK--EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA---- 458
Query: 341 PPSFHIRPASQVYPDRAPEPDCPGE-LKATAPASPRLGQSQSQADERAGTPPPAPPLPP- 398
P+ PA + P P P E T ++P + + ++ P P P
Sbjct: 459 -PTTPKEPAPTT--TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 515
Query: 399 ---PAPPLPP-PAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTA 454
PAP P PAP P P P K P TPK +P KP P +P+ A
Sbjct: 516 TKEPAPTTPKEPAPTTPKK--PAPTTPKEPAPT-----TPKEPAPTTTKKPAPTTPKEPA 568
Query: 455 SSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKET 514
+ P + P+ +KL P + E K P PEK
Sbjct: 569 PTTPKETA-PTTPKKL--------------------------TPTTPE-KLAPTTPEK-- 598
Query: 515 LLSLPAKDTP----PGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNEL 570
PA TP P PE+ + T E AP+ + P++ P P+
Sbjct: 599 ----PAPTTPEELAPTTPEEP---TPTTPEEPAPTTPKAAAPNTPKE-PAPTT------- 643
Query: 571 EARLSSAAEKEAKPSIGSLP-PKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTT 629
KE P+ P P E G L +P PTT
Sbjct: 644 --------PKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPA------------PTT 683
Query: 630 SLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGP 689
PK + P T EP P TP K T P TP + PTTP + P
Sbjct: 684 ---PKKPAPKELAPTTTKEPTSTTCDKPAPTTP-KGT-APTTPKEPA--PTTPKE----P 732
Query: 690 AIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGAR 749
A + T PTT K+ P P+KPA +E++ P+ +G S + PT
Sbjct: 733 APTTPKGTAPTTL------KEPAPT-TPKKPAPKELA-PTTTKGPTSTTSDKPAPTTPKE 784
Query: 750 SSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGL 809
++ P + +P + P P + S V PT + EP + + P
Sbjct: 785 TAPTTPKEPAPTTPKKPAPTTPETPPPTTSE---VSTPTTTK-------EPTTIHKSPD- 833
Query: 810 PAKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLR 869
+ P SA+PT + L + E G P AA + + + +
Sbjct: 834 ESTPELSAEPTPKALENSPK----EPGVPTTKTPAAT--------------KPEMTTTAK 875
Query: 870 DHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTE 911
D + + + + TP + T PK+ KE + TTE
Sbjct: 876 DKTTERDLRT--------TPETTTAAPKMTKETATTTEKTTE 909
Score = 74.3 bits (181), Expect = 6e-13
Identities = 130/610 (21%), Positives = 200/610 (32%), Gaps = 60/610 (9%)
Query: 415 PPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNEL 474
P P + K A PP+G ++T KS++ K P PP+ + T + E
Sbjct: 69 PTSPPSSKKAPPPSGASQTIKSTT---KRSPKPPNKKKTKKVIESEEITEEHSVSENQES 125
Query: 475 AAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLG- 533
++ S + A + KK K+ PP V E G
Sbjct: 126 SSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGL 185
Query: 534 --------GSSLTETEAAPSLTLPSVDYIPQDSPTPSV---RQIRNELEARLSSAAEKEA 582
+ T+ T P + +P PS+ E ++ E
Sbjct: 186 DNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVET 245
Query: 583 KPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIP 642
K + + + +G + + + K AK+L P S L T GPA+
Sbjct: 246 KETT-TTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALT 304
Query: 643 PKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTT 702
P P P + P T TP S PTTP + PA +T + PTT
Sbjct: 305 TPKEPTPTTPKE-------PASTTPKEPTPTTIKSAPTTPKE----PA-PTTTKSAPTTP 352
Query: 703 SQLMAEKDSGPA-GQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPG 761
+ PA P++PA P +P+ PT + P K +P
Sbjct: 353 KEPAPTTTKEPAPTTPKEPAPTTTKEP-------APTTTKSAPTTPKEPAPTTPKKPAPT 405
Query: 762 GGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEV--KEPPGLPAKPPASAQP 819
+ P P + +E A PT P EP K+P K PA P
Sbjct: 406 TPKEPAPTTPKEPTPTTPKEPA---PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP 462
Query: 820 TDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASS 879
+ P T + +P + A A S P + ++ S
Sbjct: 463 KEPA---PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 519
Query: 880 DSIFHSQGTPNS-FTVVPKLPKE-----AEKDSPLTTEIPNKWGPRLGRDAEGTELSRRH 933
+ P + P PKE ++ +P TT+ P P+ E +
Sbjct: 520 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAP-- 577
Query: 934 NWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFS 993
T P+ P E++AP+ + P +P +P EE E P P+ +
Sbjct: 578 --TTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP----EEPTPTTPEEPAPTTPKAA 631
Query: 994 --NDPEPPAP 1001
N P+ PAP
Sbjct: 632 APNTPKEPAP 641
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 119 bits (299), Expect = 1e-26
Identities = 195/819 (23%), Positives = 282/819 (34%), Gaps = 126/819 (15%)
Query: 21 TTPSTSLYATNPPWIFTQEAPEEGTG-GFDGIYYGDNRFNTVSESGTATLKARPRVRPLL 79
T+ TSL + T+E DG + T S T+ P + L
Sbjct: 270 TSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA 329
Query: 80 TFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNLRLYSSVGDLRPGQYGQDLLI 139
P G A+ TP P KE T+ + S+
Sbjct: 330 KPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA--------------- 374
Query: 140 PPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPP-----PPVL 194
P P PAP + P P+P +T P P EP P + P P P
Sbjct: 375 PTTPKEPAPTTTKSAPTTPKE---PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTT 431
Query: 195 EALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASP-HTVGTRLFPPG 253
P T P+ TP + P P P P P PAP +P T P
Sbjct: 432 PKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPA 491
Query: 254 GVTKWKSDVALNGRQAEATRASP-PRSPAEPKGSALGPNP----EPHLTFPRSFKVPP-- 306
T + A T P P +P EP + P EP T +S P
Sbjct: 492 PTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 551
Query: 307 PTPVRTS----SIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDC 362
P+P T + P + A P+K T K P+ P P ++ P+
Sbjct: 552 PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA--PTTPKEPAPTTTKKPAPTTPKEPA 609
Query: 363 PGELKATAPASPRLGQSQSQADERAGTPP--PAPPLP----PPAPPLPPPAPPLPPAAPP 416
P K TAP +P+ + + ++ A T P PAP P P P P P P P AP
Sbjct: 610 PTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEP-APT 667
Query: 417 LPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTA-----SSAPVDWRDPSQMEKLR 471
P A P TPK +P +P P +P+ TA +AP ++P+ +
Sbjct: 668 TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKK 727
Query: 472 ---NELAAYLCGSRREDRFLSHRPGPT----VAPQSKEGKKGPRLPEK----------ET 514
ELA ++ +P PT AP + + + P P++ T
Sbjct: 728 PAPKELAP--TTTKEPTSTTCDKPAPTTPKGTAPTTPK-EPAPTTPKEPAPTTPKGTAPT 784
Query: 515 LLSLPAKDTPPGVPEKSL------GGSSLTETEAAPSL---TLPSVDYIP---------- 555
L PA TP K L G +S T + AP+ T P+ P
Sbjct: 785 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 844
Query: 556 --QDSPTPSVRQIRNELEARLSSAAEK---EAKPSIGSLPPKPRLEGGRICENGADDDK- 609
++P P+ ++ + + K E+ P + + P LE E G K
Sbjct: 845 TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP-KEPGVPTTKT 903
Query: 610 --LSKPVAKNLPPQST------TLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPAT 661
+KP T T TT+ PK A + T E I T +T
Sbjct: 904 PAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTST 963
Query: 662 PPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPA 721
+ T TP K T+ TT T P + +T T+ TT E+ + P ++
Sbjct: 964 TTQDT----TPFKITTLKTT----TLAPKVTTTKKTITTTEIMNKPEETAKP---KDRAT 1012
Query: 722 SQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSP 760
+ + +TP + P++A + PT + PKT P
Sbjct: 1013 NSKATTPKPQK----PTKAPKKPTSTKK------PKTMP 1041
Score = 119 bits (298), Expect = 2e-26
Identities = 176/711 (24%), Positives = 246/711 (34%), Gaps = 121/711 (17%)
Query: 140 PPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPP------PSMAPPPPPV 193
P P PAP P+ EP +P P+T P P EP P P+ P P
Sbjct: 445 PTTPKEPAPTTPK---EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT 501
Query: 194 LEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAP-----APPAPASPHTVGTR 248
P T PS TP + PAP AP PAP AP P P T+
Sbjct: 502 TPKEPAPTTTKEPSPTTPKE---PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 558
Query: 249 LFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPT 308
P T + + A T P +P PK A +P T P+ + P T
Sbjct: 559 --EPAPTTPKEPAPTTPKKPAPTTPKEP--APTTPKEPAPTTTKKPAPTTPK--EPAPTT 612
Query: 309 PVRTS-SIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPD-RAPEPDCPGEL 366
P T+ + P + P K T + P+ P P + P + P PE P
Sbjct: 613 PKETAPTTPKKLTPTTPEKLAPTTPEKPA--PTTPE-ELAPTTPEEPTPTTPEEPAPTTP 669
Query: 367 KATAPASPRLGQSQSQADERAGTPP-PAPPLPPPAPPLPP----------PAPPLPPAAP 415
KA AP +P+ + + TP PAP P P P PAP P
Sbjct: 670 KAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPA 729
Query: 416 PLPCAQKAAHPPAGFT------KTPKSSSPALKPKPNP-----PSPENTASSAPVDWRDP 464
P A P T TPK ++P +P P P+P +AP ++P
Sbjct: 730 PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP 789
Query: 465 SQMEKLR---NELAAYLCGSRREDRFLSHRPGPTV----APQSKEGKKGPRLPEKETLLS 517
+ + ELA ++ S +P PT AP + + + P P+K
Sbjct: 790 APTTPKKPAPKELAPTT--TKGPTSTTSDKPAPTTPKETAPTTPK-EPAPTTPKK----- 841
Query: 518 LPAKDTPPGVPEKSLGGSSLTET-----------EAAPSL----TLPSVDYIPQDSPTPS 562
PA TP P + S+ T T E+ P L T +++ P++ P+
Sbjct: 842 -PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPT 900
Query: 563 VRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKL--SKPVAKNLPP 620
+ ++A +K + + + P E +K SK A
Sbjct: 901 TKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQV 960
Query: 621 QSTTLLPTTSLQPKAMLGPAIPPKAT--------------PEPAIPPK--ATLWPATPPK 664
STT TT + + + PK T PE PK AT AT PK
Sbjct: 961 TSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPK 1020
Query: 665 ATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQE 724
P P KA PT+ K + P + TT PT + P + + Q
Sbjct: 1021 ----PQKPTKAPKKPTSTKKPKTMPRVRKPKTT-PTPRKMTSTMPELNPTSRIAEAMLQT 1075
Query: 725 VSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGG--GEVP-CLYKPH 772
+ P+Q T ++ P GG GE P L +PH
Sbjct: 1076 TTRPNQ--------------TPNSKLVEVNPKSEDAGGAEGETPHMLLRPH 1112
Score = 114 bits (285), Expect = 6e-25
Identities = 188/762 (24%), Positives = 261/762 (34%), Gaps = 156/762 (20%)
Query: 164 PSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAF 223
P+P + P L P P P P P T + TP + PAP
Sbjct: 331 PTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKE---PAPTTTK 387
Query: 224 LAPPPPPVPAPAP---PAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSP 280
AP P PAP PAP +P T KS A T P +P
Sbjct: 388 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP--AP 445
Query: 281 AEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPL 340
PK A EP T P+ + P T + P + A AP+K T K P+
Sbjct: 446 TTPKEPAPTTPKEPTPTTPK--EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA---- 499
Query: 341 PPSFHIRPASQVYPDRAPEPDCPGE-LKATAPASPRLGQSQSQADERAGTPPPAPPLPP- 398
P+ PA + P P P E T ++P + + ++ P P P
Sbjct: 500 -PTTPKEPAPTT--TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 556
Query: 399 ---PAPPLPP-PAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTA 454
PAP P PAP P P P K P TPK +P KP P +P+ A
Sbjct: 557 TKEPAPTTPKEPAPTTPKK--PAPTTPKEPAPT-----TPKEPAPTTTKKPAPTTPKEPA 609
Query: 455 SSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKET 514
+ P + P+ +KL P + E K P PEK
Sbjct: 610 PTTPKETA-PTTPKKL--------------------------TPTTPE-KLAPTTPEK-- 639
Query: 515 LLSLPAKDTP----PGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNEL 570
PA TP P PE+ + T E AP+ + P++ P P+
Sbjct: 640 ----PAPTTPEELAPTTPEEP---TPTTPEEPAPTTPKAAAPNTPKE-PAPTT------- 684
Query: 571 EARLSSAAEKEAKPSIGSLP-PKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTT 629
KE P+ P P E G L +P PTT
Sbjct: 685 --------PKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPA------------PTT 724
Query: 630 SLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGP 689
PK + P T EP P TP K T P TP + PTTP + P
Sbjct: 725 ---PKKPAPKELAPTTTKEPTSTTCDKPAPTTP-KGT-APTTPKEPA--PTTPKE----P 773
Query: 690 AIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGAR 749
A + T PTT K+ P P+KPA +E++ P+ +G S + PT
Sbjct: 774 APTTPKGTAPTTL------KEPAPT-TPKKPAPKELA-PTTTKGPTSTTSDKPAPTTPKE 825
Query: 750 SSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGL 809
++ P + +P + P P + S V PT + EP + + P
Sbjct: 826 TAPTTPKEPAPTTPKKPAPTTPETPPPTTSE---VSTPTTTK-------EPTTIHKSPD- 874
Query: 810 PAKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLR 869
+ P SA+PT + L + E G P AA + + + +
Sbjct: 875 ESTPELSAEPTPKALENSPK----EPGVPTTKTPAAT--------------KPEMTTTAK 916
Query: 870 DHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTE 911
D + + + + TP + T PK+ KE + TTE
Sbjct: 917 DKTTERDLRT--------TPETTTAAPKMTKETATTTEKTTE 950
Score = 74.3 bits (181), Expect = 6e-13
Identities = 130/610 (21%), Positives = 200/610 (32%), Gaps = 60/610 (9%)
Query: 415 PPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNEL 474
P P + K A PP+G ++T KS++ K P PP+ + T + E
Sbjct: 110 PTSPPSSKKAPPPSGASQTIKSTT---KRSPKPPNKKKTKKVIESEEITEEHSVSENQES 166
Query: 475 AAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLG- 533
++ S + A + KK K+ PP V E G
Sbjct: 167 SSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGL 226
Query: 534 --------GSSLTETEAAPSLTLPSVDYIPQDSPTPSV---RQIRNELEARLSSAAEKEA 582
+ T+ T P + +P PS+ E ++ E
Sbjct: 227 DNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVET 286
Query: 583 KPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIP 642
K + + + +G + + + K AK+L P S L T GPA+
Sbjct: 287 KETT-TTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALT 345
Query: 643 PKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTT 702
P P P + P T TP S PTTP + PA +T + PTT
Sbjct: 346 TPKEPTPTTPKE-------PASTTPKEPTPTTIKSAPTTPKE----PA-PTTTKSAPTTP 393
Query: 703 SQLMAEKDSGPA-GQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPG 761
+ PA P++PA P +P+ PT + P K +P
Sbjct: 394 KEPAPTTTKEPAPTTPKEPAPTTTKEP-------APTTTKSAPTTPKEPAPTTPKKPAPT 446
Query: 762 GGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEV--KEPPGLPAKPPASAQP 819
+ P P + +E A PT P EP K+P K PA P
Sbjct: 447 TPKEPAPTTPKEPTPTTPKEPA---PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTP 503
Query: 820 TDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASS 879
+ P T + +P + A A S P + ++ S
Sbjct: 504 KEPA---PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP 560
Query: 880 DSIFHSQGTPNS-FTVVPKLPKE-----AEKDSPLTTEIPNKWGPRLGRDAEGTELSRRH 933
+ P + P PKE ++ +P TT+ P P+ E +
Sbjct: 561 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAP-- 618
Query: 934 NWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFS 993
T P+ P E++AP+ + P +P +P EE E P P+ +
Sbjct: 619 --TTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP----EEPTPTTPEEPAPTTPKAA 672
Query: 994 --NDPEPPAP 1001
N P+ PAP
Sbjct: 673 APNTPKEPAP 682
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 110 bits (274), Expect = 1e-23
Identities = 110/356 (30%), Positives = 134/356 (37%), Gaps = 42/356 (11%)
Query: 130 PGQYGQDLLIPPPPPGPAPGPP-QDISEPPGGSPLPSPPSTAPP---------PPPLLLE 179
P Q G PP PPG GPP Q ++P G P P P PP PPP +
Sbjct: 40 PPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 99
Query: 180 PPPPP---SMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPP--PPPVPAP 234
PPP S +P PP PP + P P PP P PP P PPP P
Sbjct: 100 GPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP 159
Query: 235 APPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSA-LGPNPE 293
P P + + PPG K + G Q + PP P +P+G G N
Sbjct: 160 QGPPPQGDNKSRSSRSPPG---KPQGPPPQGGNQPQG----PPPPPGKPQGPPPQGGNKP 212
Query: 294 PHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKA---PSRLPLPPSFHIRPAS 350
P + PPP S Q A+ P K +G + P P PP P
Sbjct: 213 QGPPPPGKPQGPPPQGDNKS----QSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 268
Query: 351 QV--YPDRAPEPDCP------GELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPP 402
Q P P P P G K+ + SP G+ Q + G P PP PP P
Sbjct: 269 QGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPP-GKPQGPPPQ-GGNQPQGPPPPPGKPQ 326
Query: 403 LPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAP 458
PPP P PP P + PP G +K+ + SP KP+ PP E P
Sbjct: 327 GPPPQGGNKPQGPP-PPGKPQGPPPQGGSKSRSARSPPGKPQ-GPPQQEGNNPQGP 380
Score = 90.1 bits (222), Expect = 1e-17
Identities = 92/318 (28%), Positives = 119/318 (37%), Gaps = 30/318 (9%)
Query: 152 QDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTP 211
+D+S+ S + P APP + PP P P P PP + P P P
Sbjct: 21 EDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGP-------PPQGGNQPQGPPP 73
Query: 212 PDFIPPAPPLAFLAPP--PPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQA 269
P P PP P PPP P P P + R PPG K + G Q
Sbjct: 74 PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPR-SPPG---KPQGPPPQGGNQP 129
Query: 270 EATRASPPRSPAEPKG-SALGPNPEPHLTFPRSFKVPPP---TPVRTSSIPVQEAQEAPR 325
+ PP P +P+G G N P + PPP R+S P + Q P
Sbjct: 130 Q----GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQ-GPP 184
Query: 326 KEEGATKKAPSRLP-----LPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQ 380
+ G + P P PP +P P + P G+ K+ + SP G+ Q
Sbjct: 185 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPP-GKPQ 243
Query: 381 SQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPA 440
+ G P PP PP P PPP P PP P + PP G +K+ S SP
Sbjct: 244 GPPPQ-GGNQPQGPPPPPGKPQGPPPQGGNKPQGPP-PPGKPQGPPPQGGSKSRSSRSPP 301
Query: 441 LKPKPNPPSPENTASSAP 458
KP+ PP N P
Sbjct: 302 GKPQGPPPQGGNQPQGPP 319
Score = 52.0 bits (123), Expect = 3e-06
Identities = 104/450 (23%), Positives = 144/450 (32%), Gaps = 61/450 (13%)
Query: 318 QEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLG 377
Q E +EE + A + PP +P P P+ P P G
Sbjct: 17 QNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPG 76
Query: 378 QSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSS 437
+ Q + P PP P P P P +PP + PP G +
Sbjct: 77 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPP---GKPQGPPPQGGNQPQGPP 133
Query: 438 SPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRP-GPTV 496
P KP+ PP N P + + N+ R R +P GP
Sbjct: 134 PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNK--------SRSSRSPPGKPQGP-- 183
Query: 497 APQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQ 556
PQ +GP P P K P G P + GG+ + + P P
Sbjct: 184 PPQGGNQPQGPPPP--------PGK--PQGPPPQ--GGN---KPQGPPPPGKPQGPPPQG 228
Query: 557 DSPTPSVRQIRNELEARLSSAA-EKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVA 615
D+ + S R + + + + P P P +GG + K P
Sbjct: 229 DNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP-- 286
Query: 616 KNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKA 675
PPQ + ++ P GP PP+ +P PP P PP G P
Sbjct: 287 ---PPQGGSKSRSSRSPPGKPQGP--PPQGGNQPQGPPPPPGKPQGPPPQ--GGNKP--- 336
Query: 676 TSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEG 735
GP P K P P S+ + + P G+P+ P QE + P +G
Sbjct: 337 -QGPPPPGKPQGPP---------PQGGSKSRSAR--SPPGKPQGPPQQEGNNP-----QG 379
Query: 736 SPSEATRLPTQGARSSAAFP--PKTSPGGG 763
P A P Q A P P P GG
Sbjct: 380 PPPPAGGNPQQPQAPPAGQPQGPPRPPQGG 409
Score = 52.0 bits (123), Expect = 3e-06
Identities = 107/462 (23%), Positives = 143/462 (30%), Gaps = 94/462 (20%)
Query: 373 SPRLGQSQSQ-ADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFT 431
SP L Q A + G P PP PP P PPP P PP PP G
Sbjct: 28 SPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPP---------PPPG-- 76
Query: 432 KTPKSSSPALKPKPNPPSPENTASSAPVDWR---DPSQMEKLRNELAAYLCGSRREDRFL 488
KP+ PP N P + P Q +K R+ +
Sbjct: 77 ----------KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP------------ 114
Query: 489 SHRPGPTVAPQSKEGK--KGPRLPEKETLLSLPA---KDTPPGVPEKSLGGSSLTETEAA 543
PG P + G +GP P + P K P P K G + ++
Sbjct: 115 ---PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSR 171
Query: 544 PSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICEN 603
S + P PQ P Q + P P P +GG +
Sbjct: 172 SSRSPPGK---PQGPPPQGGNQ--------------PQGPPPPPGKPQGPPPQGGNKPQG 214
Query: 604 GADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPP 663
K P PPQ + P GP PP+ +P PP P PP
Sbjct: 215 PPPPGKPQGP-----PPQGDNKSQSARSPPGKPQGP--PPQGGNQPQGPPPPPGKPQGPP 267
Query: 664 ----KATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEK 719
GP P K GP P + S + + P + GP P K
Sbjct: 268 PQGGNKPQGPPPPGK-PQGP--PPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGK 324
Query: 720 PASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLS 779
P ++ +G P + P QG S + ++ PG + P + + Q
Sbjct: 325 PQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRS--ARSPPGKPQGPPQQEGNNPQGP-- 380
Query: 780 REVAVVMPTLARGGAAGP-----GEPVEVKEPP--GLPAKPP 814
P A G P G+P PP G P++PP
Sbjct: 381 -------PPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRPP 415
Score = 44.7 bits (104), Expect = 5e-04
Identities = 44/173 (25%), Positives = 62/173 (35%), Gaps = 20/173 (11%)
Query: 953 NLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSP 1012
N PQG P P PP + + + + PPP+ N P+ P P G+ P
Sbjct: 210 NKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPP---GKPQGP 266
Query: 1013 PRNNYSDLRQLPNAG-PGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGEP 1071
P + + P G P PP G S+ + G GG + P
Sbjct: 267 PPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQ--------GP 318
Query: 1072 HRGPGLPHGGTGRSLSSPNCFGPQPGG------PEMRRVNSAGRAPPGGLHAP 1118
PG P G + + P GP P G P+ + + R+PPG P
Sbjct: 319 PPPPGKPQGPPPQGGNKPQ--GPPPPGKPQGPPPQGGSKSRSARSPPGKPQGP 369
Score = 43.5 bits (101), Expect = 0.001
Identities = 99/423 (23%), Positives = 126/423 (29%), Gaps = 85/423 (20%)
Query: 619 PPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPP----KATLGPATPLK 674
PPQ P GP PP+ +P PP P PP GP P K
Sbjct: 40 PPQGGNKPQGPPSPPGKPQGP--PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK 97
Query: 675 ATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGE 734
P K+ S P P + P G+P+ P Q + P +G
Sbjct: 98 PQGPPPQGDKSRS-PRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP---QGP 153
Query: 735 GSPSEATRLPTQG---ARSSAAFPPKTS---PGGGEVPCLYKPHCHQSSLSREVAVVMPT 788
P + P QG +RSS + P K P GG P P P
Sbjct: 154 PPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPP--------------PG 199
Query: 789 LARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHP--------------VTGEVVE 834
+G G + PPG P PP + R P G
Sbjct: 200 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPP 259
Query: 835 RGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTV 894
G P + Q G G GS ++ +S QG P
Sbjct: 260 PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGS------KSRSSRSPPGKPQGPPPQGGN 313
Query: 895 VPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNL 954
P+ P P G G +G +PQ P P
Sbjct: 314 QPQGP-------------PPPPGKPQGPPPQGGN----------KPQGP------PPPGK 344
Query: 955 PQGHPL---PKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSS 1011
PQG P KS S+ P + ++E N PPPP N +P AP G+
Sbjct: 345 PQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPP---AGQPQG 401
Query: 1012 PPR 1014
PPR
Sbjct: 402 PPR 404
Score = 43.5 bits (101), Expect = 0.001
Identities = 43/174 (24%), Positives = 59/174 (33%), Gaps = 22/174 (12%)
Query: 953 NLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPE--PPAPALQYLGRQS 1010
N PQG P P PP + + + PPP+ N P+ PP P Q
Sbjct: 148 NKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKP----QG 203
Query: 1011 SPPRNNYSDLRQLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGE 1070
PP+ P P PP G ++ + G GG +
Sbjct: 204 PPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQP--------QG 255
Query: 1071 PHRGPGLPHGGTGRSLSSPNCFGPQPGG------PEMRRVNSAGRAPPGGLHAP 1118
P PG P G + + P GP P G P+ + + R+PPG P
Sbjct: 256 PPPPPGKPQGPPPQGGNKPQ--GPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGP 307
Score = 42.7 bits (99), Expect = 0.002
Identities = 98/421 (23%), Positives = 127/421 (30%), Gaps = 72/421 (17%)
Query: 709 KDSGPAGQPEKPASQEVSTPSQARGEGSP-SEATRLPTQGARSSAAFPPKTSPGGGEVPC 767
K GP P KP +Q +G P + P QG PP P G
Sbjct: 46 KPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP-- 103
Query: 768 LYKPHCHQSSLSREVAVVMPTLARGGAAGP-----GEPVEVKEPPGLPAKPPASAQPTDE 822
Q SR P G GP +P PPG P PP Q ++
Sbjct: 104 -------QGDKSRS-----PRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP--QGGNK 149
Query: 823 LLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSI 882
P G+ +G P Q K RS + G+ P +Q +
Sbjct: 150 PQGPPPPGK--PQGPPP-------QGDNKSRSSRSPPGKPQGPPP--QGGNQPQGPPPPP 198
Query: 883 FHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKW-------GPRLGRDAEGTELSRRHNW 935
QG P P+ P K + NK G G +G +
Sbjct: 199 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPP 258
Query: 936 TKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSND 995
+PQ P N PQG P P PP + + PPP+ N
Sbjct: 259 PPGKPQGPPP----QGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQ 314
Query: 996 PE--PPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPALGFSRFPAGARYAGAGGLER 1053
P+ PP P Q PP+ P P PP G S+ + G +
Sbjct: 315 PQGPPPPPGKP----QGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPG-----K 365
Query: 1054 FSGGGRSLIKKRLYVGEPHRGPGLPHGGTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPG 1113
G + G +GP P GG + +P QP GP R P G
Sbjct: 366 PQGPPQQ-------EGNNPQGPPPPAGGNPQQPQAPP--AGQPQGPP--------RPPQG 408
Query: 1114 G 1114
G
Sbjct: 409 G 409
Score = 37.7 bits (86), Expect = 0.066
Identities = 52/214 (24%), Positives = 67/214 (31%), Gaps = 38/214 (17%)
Query: 953 NLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSP 1012
N PQG P P PP P + + PPP+ N P+ P P G+ P
Sbjct: 87 NKPQGPPPPGKPQGPP-PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP---GKPQGP 142
Query: 1013 PRNNYSDLRQLPNAG-PGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGEP 1071
P + + P G P PP G ++ S RS
Sbjct: 143 PPQGGNKPQGPPPPGKPQGPPPQGDNK----------------SRSSRS----------- 175
Query: 1072 HRGPGLPHGGTGRSLSSPNCFGPQPG---GPEMRRVNSA-GRAPPGGLHAPRLSLEGAAR 1127
PG P G + + P P PG GP + N G PPG P + ++
Sbjct: 176 --PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQ 233
Query: 1128 GAAEAKHKAPGSADYGFAPAAGRSPYTTTRYGSP 1161
A K G G G P G P
Sbjct: 234 SARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 267
Score = 37.7 bits (86), Expect = 0.066
Identities = 26/87 (29%), Positives = 30/87 (34%), Gaps = 4/87 (4%)
Query: 130 PGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPS---- 185
P Q G PPPP P PPQ S+ P P P + PPPP+
Sbjct: 329 PPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNP 388
Query: 186 MAPPPPPVLEALSPPHTLSSPSIPTPP 212
P PP + PP PP
Sbjct: 389 QQPQAPPAGQPQGPPRPPQGGRPSRPP 415
Score = 35.4 bits (80), Expect = 0.33
Identities = 52/212 (24%), Positives = 65/212 (30%), Gaps = 52/212 (24%)
Query: 955 PQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPR 1014
PQG P+ PPSP K + PPP+ N P+ P P G+ PP
Sbjct: 41 PQGGNKPQG---PPSPPGKPQG-----------PPPQGGNQPQGPPPPP---GKPQGPPP 83
Query: 1015 NNYSDLRQLPNAG-PGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGEPHR 1073
+ + P G P PP G K R P
Sbjct: 84 QGGNKPQGPPPPGKPQGPPPQGD--------------------------KSR----SPRS 113
Query: 1074 GPGLPHGGTGRSLSSPNCFGPQPG---GPEMRRVNSA-GRAPPGGLHAPRLSLEGAARGA 1129
PG P G + + P P PG GP + N G PPG P + +R +
Sbjct: 114 PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSS 173
Query: 1130 AEAKHKAPGSADYGFAPAAGRSPYTTTRYGSP 1161
K G G G P G P
Sbjct: 174 RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 205
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 108 bits (271), Expect = 2e-23
Identities = 173/686 (25%), Positives = 248/686 (36%), Gaps = 113/686 (16%)
Query: 138 LIPPPPPG----PAPGPPQDISEPPGGSPL------PSPPSTAPPPPPLLLEP------- 180
+IPP P P PP + E P + P P P P +L P
Sbjct: 10449 IIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEK 10508
Query: 181 --PPPPSMAP--PPPPVLEALSPPHTLSSPSIPTPPDFIPPAPP-----LAFLAPPPPPV 231
P PP+ P PPP V EA P + +P PP P PP + A P V
Sbjct: 10509 KVPVPPAKKPEAPPPKVPEA--PKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKV 10566
Query: 232 PAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAE--------- 282
P PP P SP P V K A ++ E T P +P E
Sbjct: 10567 PEAIPPKPESPPPEVPE--APKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPV 10624
Query: 283 --PKGSALGPN--PE-PHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSR 337
PK + P PE P + P KVP P + S P + +E EE A ++ P+
Sbjct: 10625 PPPKKPEVPPTKVPEVPKVAVPEK-KVPEAIPPKPESPPPEVFEE---PEEVALEEPPAE 10680
Query: 338 LPLPPSFHIRPASQVYPDR-APEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPL 396
+ P P V P + PE P A P L + + P PL
Sbjct: 10681 VVEEPEPAAPPQVTVPPKKPVPEKKAP----AVVAKKPELPPVKVPEVPKEVVPEKKVPL 10736
Query: 397 PPPAPPLPPPA--PPLPPAAPP---LPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPE 451
P P PPA P +P P + +K PPA + PK P L+ KP P PE
Sbjct: 10737 VVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPK--KPVLEEKPAVPVPE 10794
Query: 452 NTASSAPVDWRDPSQM---EKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKE---GKK 505
S P + +P ++ E++ E + + E+ P P V + K+ KK
Sbjct: 10795 RAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEE---PEVPPPAVPEEPKKIIPEKK 10851
Query: 506 ----------GPRLPEKETLLS----LPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSV 551
P+ PE E ++ P PP P K + + +A P +P
Sbjct: 10852 VPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEK 10911
Query: 552 DYIPQD-SPTP-----SVRQIRNELEARLSSAAEKEAKPSIGSLPP---KPRLEGGRICE 602
+P+ TP +++R L R E+ S+ P +P++E ++
Sbjct: 10912 PQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKL-- 10969
Query: 603 NGADDDKLSKPVAKNLPPQ---STTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWP 659
+K+ KP PP +PT + + + + P P+ +PAIP A P
Sbjct: 10970 -----EKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEI--KPAIPLPAP-EP 11021
Query: 660 ATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGP-AGQPE 718
P+A + P PT + P + A + A K GP G P+
Sbjct: 11022 KPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKA---EAKAPKEEAAKPKGPIKGVPK 11078
Query: 719 KPASQEVSTPSQAR----GEGSPSEA 740
K S + + R GE P EA
Sbjct: 11079 KTPSPIEAERRKLRPGSGGEKPPDEA 11104
Score = 106 bits (264), Expect = 2e-22
Identities = 184/744 (24%), Positives = 256/744 (34%), Gaps = 125/744 (16%)
Query: 157 PPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAP--------------------PPPPVLEA 196
PP G + PP ++ PP+ P PP V E
Sbjct: 10439 PPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEV 10498
Query: 197 LSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVP---APAPPAPASPHTVGTRL--FP 251
L P + +P PP P APP P VP P PP P P T++ P
Sbjct: 10499 LPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPP-PKKPEVPPTKVPEVP 10557
Query: 252 PGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVR 311
V + K A+ + + PP P PK PE KVP P +
Sbjct: 10558 KAAVPEKKVPEAIPPK----PESPPPEVPEAPKEVV----PEK--------KVPAAPPKK 10601
Query: 312 TSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAP 371
PV + EAP KE KK P P P +V PE P E P
Sbjct: 10602 PEVTPV-KVPEAP-KEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVP-EAIPPKP 10658
Query: 372 ASPRLGQSQSQADERAGTPPPAPPLPPPAPPLP-----PPAPPLPPAAPPLPCAQKAAHP 426
SP + + +E A PPA + P P P PP P+P P A+K P
Sbjct: 10659 ESPP-PEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELP 10717
Query: 427 PAGFTKTPKSSSPALK-PKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRRED 485
P + PK P K P P PE AP P+++ ++ E+ +
Sbjct: 10718 PVKVPEVPKEVVPEKKVPLVVPKKPE-----AP-----PAKVPEVPKEVV--------PE 10759
Query: 486 RFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLP-------AKDTPPGV---PEKSLGGS 535
+ ++ P V P K P +P+K L P A+ PP V PE+
Sbjct: 10760 KKVAVPKKPEVPP-----AKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEE 10814
Query: 536 SLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNEL--EARLSSAAEKEAKPSIGSLPPKP 593
+ E P +P + + P P+V + ++ E ++ + EA P P +P
Sbjct: 10815 EIAPEEEKP---VPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPP-----PKEP 10866
Query: 594 RLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPE-PAIP 652
E + KP K PP P ++ K AIP K PE P +P
Sbjct: 10867 EPE-----------KVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVP 10915
Query: 653 PKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLM------ 706
K L TP K G K P + + S P +
Sbjct: 10916 EKVEL---TPLKVPGGEKKVRKLL--PERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLE 10970
Query: 707 -AEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLP-TQGARSSAAFPPKTSPGGGE 764
+K + P P KP +EV P+ + E E T++P + A A PK P E
Sbjct: 10971 KVKKPAVPEPPPPKPV-EEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKP-EAE 11028
Query: 765 VPCLYKPHCHQSSLSREVAVVMPTLA-RGGAAGPGEPVEVKEPP--GLPAKPPASAQPTD 821
V + P V +P + + A P E + P G+P K P+ +
Sbjct: 11029 VKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAER 11088
Query: 822 ELLRHPVTGEVVERGSPMALLLAA 845
LR GE +P L A
Sbjct: 11089 RKLRPGSGGEKPPDEAPFTYQLKA 11112
Score = 91.3 bits (225), Expect = 5e-18
Identities = 207/942 (21%), Positives = 303/942 (32%), Gaps = 175/942 (18%)
Query: 137 LLIPP---PPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPP--PLLLEPPPPPSMAPPPP 191
+LIP PPP P P+ P P+P P PP P + + P P P P
Sbjct: 9991 VLIPKKEKPPPAKVPEVPKK-PVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPA 10049
Query: 192 PVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPP------PVPAPAPPAPASPHTV 245
P P P P + P P APPP PVP P
Sbjct: 10050 PKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLF 10109
Query: 246 GTRLFPPGGVTKWKSDVALNGRQA--EATRASPPRSPAEPKGSALGPN-----------P 292
+ P V + +V + E P P+ + P P
Sbjct: 10110 EEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVP 10169
Query: 293 EPHLTFPRSFKVPPPTPVRTSSIPVQEAQEA-PRKEEGATKKAPS--------RLPLPPS 343
E + KVP P PV V E + P+KEE K P R+ LP
Sbjct: 10170 EEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEKRIILPKE 10229
Query: 344 FHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPL 403
+ P +V + EP E+ P S + +E A PP P + A P
Sbjct: 10230 EEVLPV-EVTEEPEEEPISEEEIPEEPP-------SIEEVEEVA--PPRVPEVIKKAVPE 10279
Query: 404 PPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRD 463
P P APP ++K K + PA P+ PE V ++
Sbjct: 10280 APTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPE---KKVLVPKKE 10336
Query: 464 PSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDT 523
K R L + + R++ + R V E +PE+E +
Sbjct: 10337 AVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVE-----EIPEEEEFHEV----- 10386
Query: 524 PPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAK 583
E+ E E L V+ ++ V ++ EA EK
Sbjct: 10387 -----EEYFEEGEFHEVEEFIKLEQHRVE---EEHRVEKVHRVIEVFEAEEVEVFEKPKA 10438
Query: 584 PSIGS------LPPK-----------PRLEGGRICENGADDDKLSKPVAKNLPPQST-TL 625
P G +PPK P + + + ++K+ P +PP +
Sbjct: 10439 PPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEV 10498
Query: 626 LPTTSLQP--KAMLGPAIPPKATPEPAIP--PKATL----WPATPPKATLGPATPLKATS 677
LP + P K + PA P+A P P +P PK + P PPK P T +
Sbjct: 10499 LPPKEVVPEKKVPVPPAKKPEA-PPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVP 10557
Query: 678 GPTTPLKATS---GPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGE 734
P K P S +P +++ EK PA P+KP V P +A E
Sbjct: 10558 KAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEK-KVPAAPPKKPEVTPVKVP-EAPKE 10615
Query: 735 GSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGA 794
P + +P PPK EVP P EV V
Sbjct: 10616 VVPEKKVPVP----------PPKKP----EVPPTKVP---------EVPKV--------- 10643
Query: 795 AGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMA---LLLAARQRAQK 851
A P + V PP + PP + +E+ EVVE P A + + ++ +
Sbjct: 10644 AVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPE 10703
Query: 852 GRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTE 911
++ + LP VP++PKE + +
Sbjct: 10704 KKAPAVVAKKPELPP--------------------------VKVPEVPKEVVPEKKVPLV 10737
Query: 912 IPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWE-RVAPSNLPQGHPLPKSFSSPPSP 970
+P K +A ++ PE + V + V P+ +P+ P P P
Sbjct: 10738 VPKK------PEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVP 10791
Query: 971 SNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSP 1012
+R E PPPE +PE AP + + P
Sbjct: 10792 VPERAES----------PPPEVYEEPEEIAPEEEIAPEEEKP 10823
Score = 73.9 bits (180), Expect = 8e-13
Identities = 136/634 (21%), Positives = 217/634 (34%), Gaps = 108/634 (17%)
Query: 139 IPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALS 198
+ P P P P P+ + P P P P P L+PPPP P E +
Sbjct: 9795 VKPVPEEPVPTKPK--APPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIR 9852
Query: 199 PPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKW 258
T T P P P +A PVP P V L P
Sbjct: 9853 ISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEP------- 9905
Query: 259 KSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQ 318
+VA E E + + E F +V P PV+ +P +
Sbjct: 9906 -EEVAFE----EEVVTHVEEYLVEEEEEYIHEEEE----FITEEEVVPVIPVKVPEVPRK 9956
Query: 319 EAQE------APRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPA 372
E P+K+E P+++P P +P +V P P+ + P K P
Sbjct: 9957 PVPEEKKPVPVPKKKEA----PPAKVPEVPK---KPEEKV-PVLIPKKEKPPPAK--VPE 10006
Query: 373 SPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTK 432
P+ + +E+ P P PPA P P+P P+P +K PPA +
Sbjct: 10007 VPK----KPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPE 10062
Query: 433 TPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHR- 491
PK L P+ P+P AP P ++ K R + + + E+
Sbjct: 10063 VPKK----LIPEEKKPTPVPKKVEAP-----PPKVPKKREPVPVPVALPQEEEVLFEEEI 10113
Query: 492 -PGPTVAPQSKE--GKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTL 548
P V P+ +E ++ LPE+E +L ++ PP E E P
Sbjct: 10114 VPEEEVLPEEEEVLPEEEEVLPEEEEVLP-EEEEIPP-------------EEEEVP---- 10155
Query: 549 PSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDD 608
P +Y+P++ ++ E KP + P P + + +
Sbjct: 10156 PEEEYVPEEEEFVPEEEVL------------PEVKPKVPVPAPVPEI------KKKVTEK 10197
Query: 609 KLSKPVAKNLPPQSTTLLPTTSLQPKAMLGP----AIPPKATPEPAIPP-KATLWPATPP 663
K+ P + PP +P ++ K ++ P +P + T EP P P PP
Sbjct: 10198 KVVIPKKEEAPPAKVPEVP-KKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPP 10256
Query: 664 KATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQ 723
++ + P P A+ T +P + ++ PA +K +
Sbjct: 10257 S-----IEEVEEVAPPRVP--EVIKKAVPEAPTPVP-------KKVEAPPAKVSKKIPEE 10302
Query: 724 EVSTPSQARGEGSPSEATRLPTQGARSSAAFPPK 757
+V P Q + E P++ +P + P K
Sbjct: 10303 KVPVPVQKK-EAPPAKVPEVPKKVPEKKVLVPKK 10335
Score = 69.3 bits (168), Expect = 2e-11
Identities = 84/343 (24%), Positives = 118/343 (34%), Gaps = 50/343 (14%)
Query: 137 LLIPPPPPGPAPGPPQDISE--PPGGSPLPSPPSTAP------PPPPLLLEPP--PPPSM 186
L++P P P P+ E P +P P P P P+L E P P P
Sbjct: 10736 LVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPER 10795
Query: 187 APPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVG 246
A PPP E P + +P P+ P P P PP P P P
Sbjct: 10796 AESPPP--EVYEEPEEI-APEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKV 10852
Query: 247 TRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPP 306
+ P A PP+ P EP+ P +P P PP
Sbjct: 10853 PVIKKP--------------------EAPPPKEP-EPEKVIEKPKLKPRPPPP-----PP 10886
Query: 307 PTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPP---SFHIRPASQVYPDRAPEPDCP 363
P + + + P+K+ + P ++ L P + ++ P+R PEP
Sbjct: 10887 APPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEE 10946
Query: 364 GELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLP-------PAAPP 416
LK+ P + + + + PA P PPP P+ P P
Sbjct: 10947 VVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTK 11006
Query: 417 LPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPV 459
+P + A PA K PK + KP P PE T +APV
Sbjct: 11007 VPEIKPAIPLPAPEPK-PKPEAEVKTIKPPPVEPEPTPIAAPV 11048
Score = 59.3 bits (142), Expect = 2e-08
Identities = 122/608 (20%), Positives = 192/608 (31%), Gaps = 104/608 (17%)
Query: 139 IPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALS 198
I PPP P P+ I P P P P PPP + EP P PP V++
Sbjct: 9572 IEEPPPAKVPEAPKKIV-PEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEE 9630
Query: 199 PPHTLSSPSIPTPPDFIPPAPPLAFLA----PPPPPVPAPAPPAPASPHTVGTRLFP--- 251
P P+ T +A PP P P A P +L P
Sbjct: 9631 P-----LPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKRE 9685
Query: 252 ---PGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPT 308
P VT+++ V ++ + + +P R P K + E T
Sbjct: 9686 EEPPAKVTEFRKRVV---KEEKVSIEAPKREPQPIKEVTIMEEKERAYT----------- 9731
Query: 309 PVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKA 368
+ ++ VQ +E EE K+ P + Y +R E
Sbjct: 9732 -LEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQY----EEYEEREYE--------- 9777
Query: 369 TAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPA 428
R + + E P P P P+P P P APP +KA
Sbjct: 9778 ------RYEEHEEYITE--------PEKPIPVKPVPEEPVPTKPKAPPAKVLKKA----- 9818
Query: 429 GFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFL 488
P+ P PK P P P + +K+ E R +++
Sbjct: 9819 ----VPEEKVPVPIPKKLKPPPPKV----------PEEPKKVFEEKIRISITKREKEQVT 9864
Query: 489 SHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTL 548
+ P+ ++ +P KE + + P + + + T L
Sbjct: 9865 EPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVE 9924
Query: 549 PSVDYIPQDSPTPSVRQIRNELEARLSSAAEK----EAKPSIGSLPPKPRLEGGRICENG 604
+YI ++ + ++ + ++ K E KP +P K ++ E
Sbjct: 9925 EEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPV--PVPKKKEAPPAKVPE-- 9980
Query: 605 ADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIP-PKATLWPATPP 663
V K + L+P P A + P +P K PE +P P A P
Sbjct: 9981 ---------VPKKPEEKVPVLIPKKEKPPPAKV-PEVPKKPVPEEKVPVPVPKKVEAPPA 10030
Query: 664 KATLGPATPLKATSGPT-TPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPAS 722
K P P+ P P K + PA +P +L+ E + P P+K +
Sbjct: 10031 KVPEVPKKPVPEKKVPVPAPKKVEAPPA------KVPEVPKKLIPE-EKKPTPVPKKVEA 10083
Query: 723 QEVSTPSQ 730
P +
Sbjct: 10084 PPPKVPKK 10091
Score = 56.2 bits (134), Expect = 2e-07
Identities = 98/433 (22%), Positives = 144/433 (33%), Gaps = 75/433 (17%)
Query: 140 PPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPP--PLLLEPPPPPSMAPPPPPVLEAL 197
PPP P P P +P+P P PP P P + + P P P P P E
Sbjct: 9284 PPPKVPELPEKPA----PEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPA 9339
Query: 198 SPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVP-----------------APAPPAPA 240
+PP P P P + I P P PP VP P PA
Sbjct: 9340 APPKVPEVPKKPVPEEKI-PVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPA 9398
Query: 241 SPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPR 300
P P V + + V + E PP+ PA PK P + + P
Sbjct: 9399 VPE------IPKKKVPEERKPVP----RKEEEVPPPPKVPALPKKPV--PEEKVAVPVPV 9446
Query: 301 SFKVPPPTPVRTSSIPVQE----AQE-----APRKEEGATKKAPSRLPLPPSFHIRPAS- 350
+ K PPP + V+E A+E P++ E + + S S
Sbjct: 9447 AKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSI 9506
Query: 351 QVYPDRAPEPDCPGEL---------------KATAPASPRLGQSQSQADERAGTPPPAPP 395
VY + E + E+ + S R+ ++ ER P
Sbjct: 9507 SVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKP 9566
Query: 396 LPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTAS 455
P PPPA P AP +K PA K K P + +P P PE
Sbjct: 9567 KIPAKIEEPPPAK--VPEAPKKIVPEKKV--PAPVPKKEKVPPPKVPEEPKKPVPEKKVP 9622
Query: 456 SAPVDWRDPSQMEKLRNELAAYLCGSRREDRFL---SHRPGPTVAPQSKEGKKGPRLPEK 512
+ +P + + +E++ L + + P A +E K+ +PE+
Sbjct: 9623 PKVIKMEEPLPAKVTERHMQI-----TQEEKVLVAVTKKEAPPKARVPEEPKRA--VPEE 9675
Query: 513 ETLLSLPAKDTPP 525
+ L P ++ P
Sbjct: 9676 KVLKLKPKREEEP 9688
Score = 54.7 bits (130), Expect = 5e-07
Identities = 93/414 (22%), Positives = 137/414 (33%), Gaps = 72/414 (17%)
Query: 255 VTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSS 314
VT+ K VA++ R PP+ P P+ P PE P KV PP P
Sbjct: 9269 VTEEKIHVAISKRVEP-----PPKVPELPEK----PAPEEVAPVPIPKKVEPPAP----- 9314
Query: 315 IPVQEAQEAPRKEEGATKKAPSRLPL-PPSFHIRPASQVYPDRAPEPDCPGELKATAPAS 373
V E + P EE P + P PP P V ++ P P + K PA
Sbjct: 9315 -KVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVP--VAKKKEAPPAK 9371
Query: 374 PRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKT 433
Q +E+ PPPA P P +P P+P ++ PP
Sbjct: 9372 VPEVQKGVVTEEKITIVTQREESPPPAVP-EIPKKKVPEERKPVPRKEEEVPPPPKVPAL 9430
Query: 434 PKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPG 493
PK KP P E A PV + P ++ + E RF++
Sbjct: 9431 PK------KPVPE----EKVAVPVPVAKKAPPPRAEVSKKTVV------EEKRFVAEEKL 9474
Query: 494 PTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDY 553
PQ E + E+E S E+ + S E E +Y
Sbjct: 9475 SFAVPQRVEVTRHEVSAEEEWSYS---------EEEEGVSISVYREEEREEEEEAEVTEY 9525
Query: 554 IPQDSPTPSVRQ-----IRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDD 608
+ P V + I +EA + E++ K + KP++
Sbjct: 9526 EVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEK----KIVLKPKIPA----------- 9570
Query: 609 KLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPP--------KATPEPAIPPK 654
K+ +P +P ++P + +PP K PE +PPK
Sbjct: 9571 KIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPK 9624
Score = 51.6 bits (122), Expect = 4e-06
Identities = 163/802 (20%), Positives = 246/802 (30%), Gaps = 162/802 (20%)
Query: 139 IPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAP---------P 189
+ PP P P + + E P+P APP P + + P P P P
Sbjct: 9309 VEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIPVPVAKKKEAP 9368
Query: 190 PPPVLEALSPPHTLSSPSIPT-----PPDFIP------------PAPPLAFLAPPPPPVP 232
P V E T +I T PP +P P P PPPP VP
Sbjct: 9369 PAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVP 9428
Query: 233 A-PAPPAP----ASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSA 287
A P P P A P V + PP ++ T R AE K
Sbjct: 9429 ALPKKPVPEEKVAVPVPVAKKAPPP------------RAEVSKKTVVEEKRFVAEEK--- 9473
Query: 288 LGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIR 347
SF VP V + +E +EEG +
Sbjct: 9474 ------------LSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAE 9521
Query: 348 PASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPL----PPPAPPL 403
+ E +L + ++ E+ P P PPPA
Sbjct: 9522 VTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVP 9581
Query: 404 PPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKP-----NPPSPEN------ 452
P +P P P +K PP + PK P K P P P
Sbjct: 9582 EAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHM 9641
Query: 453 ------------TASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQS 500
T AP R P + ++ + E++ L +P P +
Sbjct: 9642 QITQEEKVLVAVTKKEAPPKARVPEEPKR-----------AVPEEKVLKLKPKREEEPPA 9690
Query: 501 KEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSV--------- 551
K + R+ ++E + K P + E ++ + E E A +L +V
Sbjct: 9691 KVTEFRKRVVKEEKVSIEAPKREPQPIKEVTI----MEEKERAYTLEEEAVSVQREEEYE 9746
Query: 552 -----DY--IPQDSPTPSVRQIRNELEARLSSAAEKE-----------AKP-SIGSLPPK 592
DY + PT Q E E E KP +P K
Sbjct: 9747 EYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTK 9806
Query: 593 PRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKAT------ 646
P+ ++ + ++K+ P+ K L P P +PK + I T
Sbjct: 9807 PKAPPAKVLKKAVPEEKVPVPIPKKLKPPP----PKVPEEPKKVFEEKIRISITKREKEQ 9862
Query: 647 -PEPA----IPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTT 701
EPA + PK + P A P++ P P + P + + T
Sbjct: 9863 VTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRV---PEVPKELE--PEEVAFEEEVVTH 9917
Query: 702 TSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPG 761
+ + E++ + E+ ++E P E R P + P K
Sbjct: 9918 VEEYLVEEEEEYIHEEEEFITEEEVVPVI---PVKVPEVPRKPVPEEKKPVPVPKKKEAP 9974
Query: 762 GGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAG----PGEPV-EVKEPPGLPAKPPAS 816
+VP + K +V V++P + A P +PV E K P +P K A
Sbjct: 9975 PAKVPEVPK------KPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAP 10028
Query: 817 AQPTDELLRHPVTGEVVERGSP 838
E+ + PV + V +P
Sbjct: 10029 PAKVPEVPKKPVPEKKVPVPAP 10050
Score = 48.5 bits (114), Expect = 4e-05
Identities = 148/714 (20%), Positives = 215/714 (30%), Gaps = 98/714 (13%)
Query: 136 DLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLE 195
+L P P P P I P P PP APP P LL P P PPP +E
Sbjct: 8931 ELKPPDIPDSRVPIPTMPIRAVP---PEEIPPVVAPPIPLLL----PTPEEKKPPPKRIE 8983
Query: 196 ALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPP-VPAPAPPAPASPHTVGTRLFPPGG 254
+ + P + P + PPP +PA AP
Sbjct: 8984 VTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKAPEI---------------- 9027
Query: 255 VTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPH---LTFPRSFKVPPPTPVR 311
DV+ + + + + + K + H F SF+ P
Sbjct: 9028 -----IDVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVHKEKRVFIESFEEPYD---E 9079
Query: 312 TSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIR-----PASQVYPDRAPEPDCPGEL 366
P E E P EE ++ H Q Y +R D E
Sbjct: 9080 LEVEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVHEEWEEDFEEGQEYYEREEGYDEGEEE 9139
Query: 367 KATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHP 426
A + Q Q + E + +P P PP P +++
Sbjct: 9140 WEEAYQEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEE 9199
Query: 427 PAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGS---RR 483
TK P+ S + KP+ R P Q E + ++ A
Sbjct: 9200 KVQVTKVPEVSKKIVPQKPS---------------RTPVQEEVIEVKVPAVHTKKMVISE 9244
Query: 484 EDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAA 543
E F + V+ E +K EK + + PP VPE E A
Sbjct: 9245 EKMFFASHTEEEVSVTVPEVQKEIVTEEKIHVAISKRVEPPPKVPELP---EKPAPEEVA 9301
Query: 544 PSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICEN 603
P V+ P + + E + E A P + +P KP
Sbjct: 9302 PVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKP---------- 9351
Query: 604 GADDDKLSKPVA--KNLPP-------------QSTTLLPTTSLQPKAMLGPAIPPKATPE 648
++K+ PVA K PP + T++ P + P IP K PE
Sbjct: 9352 -VPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAV-PEIPKKKVPE 9409
Query: 649 PAIP-PKATLWPATPPKATLGPATPL--KATSGPTTPLKATSGPAIASTATTLPTTTSQL 705
P P+ PPK P P+ + + P K P + T+ +
Sbjct: 9410 ERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFV 9469
Query: 706 MAEKDSGPAGQPEKPASQEVSTPSQ-ARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGE 764
EK S Q + EVS + + E + + + R T E
Sbjct: 9470 AEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVME 9529
Query: 765 VPCLY----KPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPP 814
P Y K H + E A V + P P +++EPP PAK P
Sbjct: 9530 EPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPP--PAKVP 9581
Score = 47.4 bits (111), Expect = 8e-05
Identities = 107/519 (20%), Positives = 182/519 (35%), Gaps = 138/519 (26%)
Query: 504 KKGPRLPEKETLLSL--PAKDTPPGV-PEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPT 560
+K R P +E ++ + PA T V E+ + +S TE E S+T+P V
Sbjct: 9216 QKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEV--SVTVPEVQ-------- 9265
Query: 561 PSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPP 620
++I E + ++ + E P + LP KP A ++ P+ K + P
Sbjct: 9266 ---KEIVTEEKIHVAISKRVEPPPKVPELPEKP-----------APEEVAPVPIPKKVEP 9311
Query: 621 QSTTLLPTTSLQPKAMLGPAIPPKATPEPAIP-PKATLWPATPPKATLGPATPLKATSGP 679
+ PK P +P K PE P P PA PPK P P+ P
Sbjct: 9312 PA----------PKV---PEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEEKIP 9358
Query: 680 TTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKP---ASQEVSTPSQARGEGS 736
K +K++ PA PE ++E T R E
Sbjct: 9359 VPVAK-----------------------KKEAPPAKVPEVQKGVVTEEKITIVTQREESP 9395
Query: 737 PSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAG 796
P +P + +VP KP
Sbjct: 9396 PPAVPEIPKK-----------------KVPEERKPV------------------------ 9414
Query: 797 PGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVG 856
P + EV PP +PA P +E + PV V ++ P ++ + ++ R V
Sbjct: 9415 PRKEEEVPPPPKVPALPKKPVP--EEKVAVPVP--VAKKAPPPRAEVSKKTVVEEKRFVA 9470
Query: 857 AALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTT----EI 912
++P + H+ A + + + S +V + +E E+++ +T E
Sbjct: 9471 EEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEE 9530
Query: 913 PNKW---------GPRLGRDAEGTELS-RRHNWTKPEPQAPVAWERVAPSNLPQGHPLPK 962
P ++ R+ +AE E++ R+ +P+ P E P+ +P+
Sbjct: 9531 PEEYVVEEKLHIISKRV--EAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIV 9588
Query: 963 SFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAP 1001
P+P K+E+ PPP+ +P+ P P
Sbjct: 9589 PEKKVPAPVPKKEKV----------PPPKVPEEPKKPVP 9617
Score = 34.3 bits (77), Expect = 0.73
Identities = 31/119 (26%), Positives = 51/119 (42%), Gaps = 6/119 (5%)
Query: 349 ASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLP--PPAPPLPPP 406
A Q P + P P P + K+ +P P + A +++ +P P P P P P
Sbjct: 245 AGQQLPHKTP-PRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAPTPSP 303
Query: 407 APPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPEN--TASSAPVDWRD 463
+ PAA ++ P KT ++S+ A P+ PP + ASS+ + R+
Sbjct: 304 VRSVSPAARISTSPIRSVRSPLLMRKT-QASTVATGPEVPPPWKQEGYVASSSEAEMRE 361
Score = 32.3 bits (72), Expect = 2.8
Identities = 34/120 (28%), Positives = 42/120 (35%), Gaps = 22/120 (18%)
Query: 360 PDCPGELKATAPASPRLGQSQSQADERAGT--------PPPAPPLPPPAPPLP----PPA 407
PD G A PR G+++S A+ T PP P P P +P PP
Sbjct: 8897 PDDEGVYSVIARLEPR-GEARSTAELYLTTKEIKLELKPPDIPDSRVPIPTMPIRAVPPE 8955
Query: 408 PPLPPAAPP----LPCAQKAAHPPAGFTKTPK-----SSSPALKPKPNPPSPENTASSAP 458
P APP LP ++ PP T K + KPK P E P
Sbjct: 8956 EIPPVVAPPIPLLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPP 9015
Score = 31.2 bits (69), Expect = 6.1
Identities = 21/61 (34%), Positives = 26/61 (42%), Gaps = 4/61 (6%)
Query: 181 PPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPA 240
PP P P PP + A + SPS P P+P AP P PV + +P A
Sbjct: 258 PPKPKSRSPTPPSIAAKAQLARQQSPS----PIRHSPSPVRHVRAPTPSPVRSVSPAARI 313
Query: 241 S 241
S
Sbjct: 314 S 314
Score = 31.2 bits (69), Expect = 6.1
Identities = 38/163 (23%), Positives = 61/163 (37%), Gaps = 34/163 (20%)
Query: 889 PNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPE-PQAPVAWE 947
P VP +PK+ E +P E+P K P + + PE P+ PV E
Sbjct: 9297 PEEVAPVP-IPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKPVPEE 9355
Query: 948 RVA----------PSNLPQGHP-----------LPKSFSSPPS----PSNKREEEEEEF- 981
++ P+ +P+ + S PP+ P K EE +
Sbjct: 9356 KIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVP 9415
Query: 982 -NFEVIPPPPEFSNDPEPPAPALQY-----LGRQSSPPRNNYS 1018
E +PPPP+ P+ P P + + +++ PPR S
Sbjct: 9416 RKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAPPPRAEVS 9458
Score = 30.8 bits (68), Expect = 8.0
Identities = 24/89 (26%), Positives = 37/89 (41%), Gaps = 11/89 (12%)
Query: 139 IPPPPPGPAPGPPQDISEPP-GGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEAL 197
IPP P +P PP ++ PSP +P P + P P P + P + +
Sbjct: 257 IPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAPTPSPVRSVSPAARI-ST 315
Query: 198 SPPHTLSSP---------SIPTPPDFIPP 217
SP ++ SP ++ T P+ PP
Sbjct: 316 SPIRSVRSPLLMRKTQASTVATGPEVPPP 344
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 107 bits (267), Expect = 7e-23
Identities = 215/921 (23%), Positives = 315/921 (34%), Gaps = 131/921 (14%)
Query: 140 PPPPPGPAPGPPQDISEPPGGSPLPS--PPSTAPPP--PPLLLEPPPPPSMAPPPPPVLE 195
PP PGPA PPQ PG + PS P ST PPP P P P PP
Sbjct: 480 PPQQPGPAKPPPQQ----PGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPG 535
Query: 196 ALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPA---PPAPASPHTVGTRLFPP 252
+ P SP+ P+ P P PP +P+ PP+ P T+ P
Sbjct: 536 SAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTI----CPL 591
Query: 253 GGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRT 312
T+ V T S G NP PHLT + + R
Sbjct: 592 CNTTELLLHVPEKANFNTCTECQTTVC------SLCGFNPNPHLTEVKEWLCLNCQMKRA 645
Query: 313 --------SSIPVQEAQEAPRKEEGA-TKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCP 363
S P + + AP A +K +P P P + +APEP P
Sbjct: 646 LGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDL--SKAPEPKKP 703
Query: 364 GELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKA 423
L P L S S +A PP A L PAPP P P AP K
Sbjct: 704 PPLVK----QPTLHGSPSA---KAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQ 756
Query: 424 AHPPAGFTKTPKSSSPALKP-----KPNPPSPENTASSAPVDWRDPSQM-----EKLRNE 473
T SSS KP K + E T D PSQ EK+
Sbjct: 757 PKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF 816
Query: 474 LAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLG 533
+ + + + +SH PGP+ +SK K+ + +KE K +P +
Sbjct: 817 DSKAIPRPASDSKIISH-PGPS--SESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPK 873
Query: 534 GSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKP 593
GS T P T PQ SP P + R L + A K S P P
Sbjct: 874 GSP---TPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPK-------SQPTTP 923
Query: 594 R-LEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQ-PKAMLGPAIPPKATPEPAI 651
+ G++ GA ++ Q++ L+ T P + GP P K P P+
Sbjct: 924 QETVTGKLFGFGA-----------SIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQ 972
Query: 652 PPKATLWPATPPKATLGPATPLKATSGPT-TPLKATSGPAIASTATTLPTTTSQLMAEKD 710
PP + PPK+T G A P A S P KA + + A P T + EK
Sbjct: 973 PPTS----QGPPKST-GQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAP-TVKRTETEKK 1026
Query: 711 SGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVP---- 766
P + ++ + E SP + P ++ K P
Sbjct: 1027 PPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPL--CKTELNIGSKDPPNFNTCTECKN 1084
Query: 767 -----CLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTD 821
C + P H + + + + T A G+ ++++ P P+ P AS P
Sbjct: 1085 QVCNLCGFNPTPHLTEIQEWLCLNCQT----QRAISGQLGDIRKMPPAPSGPKASPMPV- 1139
Query: 822 ELLRHPVTGEVVERGSPMALLLAARQRAQKG--------RSVGAALGRSSLPGSLRDHSH 873
P + P + L +Q + V L +P +
Sbjct: 1140 -----PTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQK 1194
Query: 874 QAEA-----SSDSIFHSQGTPNSFTVVPKLPK-EAEKDSPLTTE-IPNKWGPRLGRDAE- 925
Q E+ + ++ + P ++P+ K +E+ PL E P +L +A+
Sbjct: 1195 QEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKT 1254
Query: 926 GTELSRRHNWTKPEPQAPVAWE----RVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEF 981
++H+ K + Q +A E RVAP + +G PS + + +E++
Sbjct: 1255 SAPEEQKHDLLKSQVQ--IAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDK 1312
Query: 982 NFEVIPPPPEFSNDPEPPAPA 1002
+ I P+PP A
Sbjct: 1313 TTKTI------KEQPQPPCTA 1327
Score = 106 bits (264), Expect = 2e-22
Identities = 185/785 (23%), Positives = 263/785 (33%), Gaps = 161/785 (20%)
Query: 140 PPPPPGPAPGPPQ-------------DISEPP--------GGSPLPSPPSTAPPPPPLLL 178
PP P GP Q D S P G S PS PS + PP +
Sbjct: 251 PPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPP---IQ 307
Query: 179 EPPP--PPSMAP----PPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVP 232
+P P PP+ P P + + P L+ P P PP P PP P+
Sbjct: 308 QPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLG 367
Query: 233 APAPPA-------PASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKG 285
PPA P+S L P GV K A + P + P + G
Sbjct: 368 PAKPPAQQTGSEKPSSEQPGPKALAQPPGVGK-----------TPAQQPGPAKPPTQQVG 416
Query: 286 SALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFH 345
+ +P L P P TPV+ AQ+A + A + P+
Sbjct: 417 TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPT--------- 467
Query: 346 IRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLP- 404
+P SQ+ P P PG K P + G ++ + + T PP P P PA P P
Sbjct: 468 -KPPSQLPGPAKPPPQQPGPAK---PPPQQPGSAKPPSQQPGSTKPP-PQQPGPAKPSPQ 522
Query: 405 PPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDP 464
P PP+ P A P +S+ P + P T S P
Sbjct: 523 QPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVS--------P 574
Query: 465 SQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGK----------KGPRLPEKET 514
S + L +C L H P E + P L E +
Sbjct: 575 SAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKE 634
Query: 515 LLSLPAK---------DTPPGVPEKSLGGSSLTETEAA------PSLTLPSVDYIPQD-- 557
L L + P P+ L + +T T A P T P D P+
Sbjct: 635 WLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDL 694
Query: 558 -------SPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKL 610
P P V+Q L S+ A++ + S P P+ E ++
Sbjct: 695 SKAPEPKKPPPLVKQ--PTLHGSPSAKAKQPPEADSLSKPAPPK-------EPSVPSEQD 745
Query: 611 SKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPA----TPPKAT 666
PVA + P Q + PTT L + AT +P IP A TPP T
Sbjct: 746 KAPVADDKPKQPKMVKPTTDLVSSS--------SATTKPDIPSSKVQSQAEEKTTPPLKT 797
Query: 667 --LGPATPLKATSGPTTPL--KATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKP-- 720
P+ T +P KA PA S + P +S+ +K P + E+P
Sbjct: 798 DSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKK 857
Query: 721 ASQEVSTPSQAR--GEGSPSEATRLPTQGAR---------------------SSAAFPPK 757
A ++S A+ +GSP+ PT G S PK
Sbjct: 858 AQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPK 917
Query: 758 TSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGG---AAGPGEPVEVKEPPGLPAKPP 814
+ P + K +S+ + + ++ T + G +GPG P +K+ P P++PP
Sbjct: 918 SQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAP--MKQAPA-PSQPP 974
Query: 815 ASAQP 819
S P
Sbjct: 975 TSQGP 979
Score = 88.6 bits (218), Expect = 3e-17
Identities = 211/1009 (20%), Positives = 319/1009 (31%), Gaps = 139/1009 (13%)
Query: 199 PPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKW 258
PP SPS+ + PP PP P PA P + T T +
Sbjct: 72 PPAAAESPSMHRKQELDSSHPPKQSGRPPDPG--RPAQPGLSKSRTTDT----------F 119
Query: 259 KSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQ 318
+S+ L GR +S + K L+ + + + +
Sbjct: 120 RSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLI 179
Query: 319 EAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRA-PEPDCPGELKATAPASPRLG 377
EA ++E +K + P I+P Q P + P+ PG +P+
Sbjct: 180 SDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPK-- 237
Query: 378 QSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSS 437
SQ E+ + PP P P P LP + A+ P +
Sbjct: 238 SISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAK-----LPLQRDASRPQTKQADIVRGE 292
Query: 438 SPALKPKPNPPSPENTASSAPVDWRDPSQM---EKLRNELAAYLCGSRREDRFLSHRPGP 494
S KP+ PSP P + P+Q EK + A + L+ +PG
Sbjct: 293 SV----KPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGT 348
Query: 495 TVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTL---PSV 551
P G P PA+ P P GS +E L P V
Sbjct: 349 VKPPVQPPGTTKP-----------PAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGV 397
Query: 552 DYIPQDSPTPS---VRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDD 608
P P P+ +Q+ + AK + P + G+I A
Sbjct: 398 GKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPG 457
Query: 609 KLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLG 668
K S + P + + LP + P GPA PP P A PP PP G
Sbjct: 458 KTS--AQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPG 515
Query: 669 PATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTP 728
PA P G T P G A K S P KP++Q+ + P
Sbjct: 516 PAKPSPQQPGSTKPPSQQPGSA------------------KPSAQQPSPAKPSAQQSTKP 557
Query: 729 SQARGEGSPSE-------ATRLPTQGARSSAAFPPKTSPGGGEVP--------------- 766
G G P + A + P+QG + T+ VP
Sbjct: 558 VSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTV 617
Query: 767 ---CLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDEL 823
C + P+ H + + + + + G PV P L P + +
Sbjct: 618 CSLCGFNPNPHLTEVKEWLC--LNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKS 675
Query: 824 LRHPVTGEVVERGSPMALLLAARQRAQKGRSV------GAALGRSSLPGSLRDHSHQAEA 877
P + +P L A + + V G+ ++ P S A
Sbjct: 676 SPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPP 735
Query: 878 SSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRL------GRDAEGTELSR 931
S+ Q PK PK + + L + P + + E T
Sbjct: 736 KEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPL 795
Query: 932 RHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFS---SPPSPSN-----------KREEE 977
+ + KP P E+V+P + + P P S S S P PS+ +++EE
Sbjct: 796 KTDSAKPSQSFPPTGEKVSPFD-SKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEE 854
Query: 978 EEEFNFEVIPPP---PEFSNDPEPPAP---ALQYLGRQSSPPRNNYSDLRQLPNAG--PG 1029
++ ++ P P P P PP P A Q + P+ R N G
Sbjct: 855 PKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITD 914
Query: 1030 APPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGEPHRGPGLPHGGTGRSLSSP 1089
AP + P + G + G G S+ + + PG PH +G +P
Sbjct: 915 APKSQ-----PTTPQETVTG---KLFGFGASIFSQASNLISTAGQPG-PHSQSGP--GAP 963
Query: 1090 NCFGPQPGGPEMRR--VNSAGRAPPGGLHAPRLSLEGAARGAAEAKHKA 1136
P P P + S G+APP + + E A A + + KA
Sbjct: 964 MKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKA 1012
Score = 63.9 bits (154), Expect = 9e-10
Identities = 79/278 (28%), Positives = 102/278 (36%), Gaps = 77/278 (27%)
Query: 347 RPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPP 406
+PASQ+ P +P ++ PA PR S D A PPP PP PPP PP PPP
Sbjct: 2371 KPASQL-PSGSPSV-------SSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPP 2422
Query: 407 -APPLPP----------------AAP---------------------------------- 415
PPLPP A+P
Sbjct: 2423 PPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTA 2482
Query: 416 PLPCAQKAAHPPAG--FTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNE 473
P P K + P+G FT P+ S P + PKP P T + P D L +
Sbjct: 2483 PPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLP-TTTQKPTDIHPKPTGLSLTSS 2541
Query: 474 LAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPR----LPEKETLLSLPAKDTPPGVPE 529
+ L S D L P PT K PR L E +++LP++ PG P
Sbjct: 2542 MTLNLVTS--ADYKL---PSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSE---PGTPT 2593
Query: 530 KSLGGSSLTETE-AAPSLTLPSVDYIPQDSPTPSVRQI 566
S ++T +PS L SV+ P S P V +
Sbjct: 2594 DSSASQAITSWPLGSPSKDLVSVE--PVFSVVPPVTAV 2629
Score = 61.6 bits (148), Expect = 4e-09
Identities = 55/176 (31%), Positives = 65/176 (36%), Gaps = 23/176 (13%)
Query: 140 PPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPP---PPLLLEPPPPPSMAPPPPPVLEA 196
PPPPP P P PP PP P P PP T+P P P L P + A P +
Sbjct: 2407 PPPPPPPPPPPP-----PPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTT 2461
Query: 197 LSPPHTLSSPSIP------TPPDFIPPAPP-----LAFLAPPPPPVP--APAPPAPASPH 243
L L S +P T P +PP P L F P P P AP P P P
Sbjct: 2462 LETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPT 2521
Query: 244 TV--GTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLT 297
T T + P S + LN + + P SP P + P LT
Sbjct: 2522 TTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLT 2577
Score = 60.1 bits (144), Expect = 1e-08
Identities = 68/269 (25%), Positives = 91/269 (33%), Gaps = 72/269 (26%)
Query: 145 GPAPGPPQDISEPPGGSP----LPSPP-----------STAPPPPPLLLEPPPPPSMAPP 189
G G + S+ P GSP LP+ P S PPPPP PPPPP PP
Sbjct: 2364 GETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPP 2423
Query: 190 PPPVLEALSPPHTL--------SSPSIPTPPDFIP---------------PAPPLAFLAP 226
PPP+ SP T+ +SP P F P + AP
Sbjct: 2424 PPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP 2483
Query: 227 PP-PPVPAPAP--------PAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPP 277
PP PP P+ P P P+ P + P Q T P
Sbjct: 2484 PPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIP----------------QLPTTTQKPT 2527
Query: 278 RSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATK----- 332
+P G +L + +L +K+P P TS + + +PR + T+
Sbjct: 2528 DIHPKPTGLSLTSSMTLNLVTSADYKLPSP----TSPLSPHSNKSSPRFSKSLTETYVVI 2583
Query: 333 KAPSRLPLPPSFHIRPASQVYPDRAPEPD 361
PS P A +P +P D
Sbjct: 2584 TLPSEPGTPTDSSASQAITSWPLGSPSKD 2612
Score = 42.7 bits (99), Expect = 0.002
Identities = 81/353 (22%), Positives = 123/353 (34%), Gaps = 60/353 (16%)
Query: 567 RNELEARLSSAAEKEA-----KPSIGSLPPKPRLEGGRIC-------ENGADDDKLSKPV 614
+ ELEA + ++ E S+ +LP K +L E A P
Sbjct: 2323 KKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPS 2382
Query: 615 AKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKAT--LWPATPPKATLGP--- 669
+LP + ++SL A P PP P P PP L P T PK T+ P
Sbjct: 2383 VSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKK 2442
Query: 670 ---------ATPL--KATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSG------ 712
ATPL T+ TT + ++G + TT P + SG
Sbjct: 2443 LTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHR 2502
Query: 713 --PAGQP--EKPASQEVSTPSQARGEGSPS----EATRLPTQGARSSAAF--PPKTSPGG 762
P+ P KP ++ T +Q + P T T +SA + P TSP
Sbjct: 2503 PEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSP-- 2560
Query: 763 GEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVE-------VKEPPGLPAKPPA 815
PH ++SS ++ + + PG P + P G P+K
Sbjct: 2561 ------LSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLV 2614
Query: 816 SAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSL 868
S +P ++ PVT + S ++ + V A + P S+
Sbjct: 2615 SVEPVFSVV-PPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTSV 2666
Score = 32.7 bits (73), Expect = 2.1
Identities = 18/62 (29%), Positives = 26/62 (41%)
Query: 121 LYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEP 180
LYS + L PG+ + +P P P PQ + P P+ P TA + +P
Sbjct: 3623 LYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDP 3682
Query: 181 PP 182
P
Sbjct: 3683 KP 3684
Score = 32.0 bits (71), Expect = 3.6
Identities = 39/147 (26%), Positives = 48/147 (32%), Gaps = 29/147 (19%)
Query: 165 SPPSTAPPPPPLL------LEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIP-- 216
SPP P PL L +AP PP + L P + SP F+P
Sbjct: 3585 SPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYE 3644
Query: 217 -PAP----PLAFLAPPPPPVPAPAP------------PAPASPHTVGTRLFP----PGGV 255
P P P L P VP +P P P SP + P G
Sbjct: 3645 KPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYT 3704
Query: 256 TKWKSDVALNGRQAEATRASPPRSPAE 282
TK + +G Q + R P P E
Sbjct: 3705 TKGSQTMTSSGAQKKVKRTLPNPPPEE 3731
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 107 bits (267), Expect = 7e-23
Identities = 215/921 (23%), Positives = 315/921 (34%), Gaps = 131/921 (14%)
Query: 140 PPPPPGPAPGPPQDISEPPGGSPLPS--PPSTAPPP--PPLLLEPPPPPSMAPPPPPVLE 195
PP PGPA PPQ PG + PS P ST PPP P P P PP
Sbjct: 480 PPQQPGPAKPPPQQ----PGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPG 535
Query: 196 ALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPA---PPAPASPHTVGTRLFPP 252
+ P SP+ P+ P P PP +P+ PP+ P T+ P
Sbjct: 536 SAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTI----CPL 591
Query: 253 GGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRT 312
T+ V T S G NP PHLT + + R
Sbjct: 592 CNTTELLLHVPEKANFNTCTECQTTVC------SLCGFNPNPHLTEVKEWLCLNCQMKRA 645
Query: 313 --------SSIPVQEAQEAPRKEEGA-TKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCP 363
S P + + AP A +K +P P P + +APEP P
Sbjct: 646 LGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDL--SKAPEPKKP 703
Query: 364 GELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKA 423
L P L S S +A PP A L PAPP P P AP K
Sbjct: 704 PPLVK----QPTLHGSPSA---KAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQ 756
Query: 424 AHPPAGFTKTPKSSSPALKP-----KPNPPSPENTASSAPVDWRDPSQM-----EKLRNE 473
T SSS KP K + E T D PSQ EK+
Sbjct: 757 PKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPF 816
Query: 474 LAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLG 533
+ + + + +SH PGP+ +SK K+ + +KE K +P +
Sbjct: 817 DSKAIPRPASDSKIISH-PGPS--SESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPK 873
Query: 534 GSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKP 593
GS T P T PQ SP P + R L + A K S P P
Sbjct: 874 GSP---TPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPK-------SQPTTP 923
Query: 594 R-LEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQ-PKAMLGPAIPPKATPEPAI 651
+ G++ GA ++ Q++ L+ T P + GP P K P P+
Sbjct: 924 QETVTGKLFGFGA-----------SIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQ 972
Query: 652 PPKATLWPATPPKATLGPATPLKATSGPT-TPLKATSGPAIASTATTLPTTTSQLMAEKD 710
PP + PPK+T G A P A S P KA + + A P T + EK
Sbjct: 973 PPTS----QGPPKST-GQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAP-TVKRTETEKK 1026
Query: 711 SGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVP---- 766
P + ++ + E SP + P ++ K P
Sbjct: 1027 PPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPL--CKTELNIGSKDPPNFNTCTECKN 1084
Query: 767 -----CLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTD 821
C + P H + + + + T A G+ ++++ P P+ P AS P
Sbjct: 1085 QVCNLCGFNPTPHLTEIQEWLCLNCQT----QRAISGQLGDIRKMPPAPSGPKASPMPV- 1139
Query: 822 ELLRHPVTGEVVERGSPMALLLAARQRAQKG--------RSVGAALGRSSLPGSLRDHSH 873
P + P + L +Q + V L +P +
Sbjct: 1140 -----PTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQK 1194
Query: 874 QAEA-----SSDSIFHSQGTPNSFTVVPKLPK-EAEKDSPLTTE-IPNKWGPRLGRDAE- 925
Q E+ + ++ + P ++P+ K +E+ PL E P +L +A+
Sbjct: 1195 QEESKLEKDKASALQEKKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKT 1254
Query: 926 GTELSRRHNWTKPEPQAPVAWE----RVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEF 981
++H+ K + Q +A E RVAP + +G PS + + +E++
Sbjct: 1255 SAPEEQKHDLLKSQVQ--IAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDK 1312
Query: 982 NFEVIPPPPEFSNDPEPPAPA 1002
+ I P+PP A
Sbjct: 1313 TTKTI------KEQPQPPCTA 1327
Score = 106 bits (264), Expect = 2e-22
Identities = 185/785 (23%), Positives = 263/785 (33%), Gaps = 161/785 (20%)
Query: 140 PPPPPGPAPGPPQ-------------DISEPP--------GGSPLPSPPSTAPPPPPLLL 178
PP P GP Q D S P G S PS PS + PP +
Sbjct: 251 PPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPP---IQ 307
Query: 179 EPPP--PPSMAP----PPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVP 232
+P P PP+ P P + + P L+ P P PP P PP P+
Sbjct: 308 QPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLG 367
Query: 233 APAPPA-------PASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKG 285
PPA P+S L P GV K A + P + P + G
Sbjct: 368 PAKPPAQQTGSEKPSSEQPGPKALAQPPGVGK-----------TPAQQPGPAKPPTQQVG 416
Query: 286 SALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFH 345
+ +P L P P TPV+ AQ+A + A + P+
Sbjct: 417 TPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPT--------- 467
Query: 346 IRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLP- 404
+P SQ+ P P PG K P + G ++ + + T PP P P PA P P
Sbjct: 468 -KPPSQLPGPAKPPPQQPGPAK---PPPQQPGSAKPPSQQPGSTKPP-PQQPGPAKPSPQ 522
Query: 405 PPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDP 464
P PP+ P A P +S+ P + P T S P
Sbjct: 523 QPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVS--------P 574
Query: 465 SQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGK----------KGPRLPEKET 514
S + L +C L H P E + P L E +
Sbjct: 575 SAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKE 634
Query: 515 LLSLPAK---------DTPPGVPEKSLGGSSLTETEAA------PSLTLPSVDYIPQD-- 557
L L + P P+ L + +T T A P T P D P+
Sbjct: 635 WLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDL 694
Query: 558 -------SPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKL 610
P P V+Q L S+ A++ + S P P+ E ++
Sbjct: 695 SKAPEPKKPPPLVKQ--PTLHGSPSAKAKQPPEADSLSKPAPPK-------EPSVPSEQD 745
Query: 611 SKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPA----TPPKAT 666
PVA + P Q + PTT L + AT +P IP A TPP T
Sbjct: 746 KAPVADDKPKQPKMVKPTTDLVSSS--------SATTKPDIPSSKVQSQAEEKTTPPLKT 797
Query: 667 --LGPATPLKATSGPTTPL--KATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKP-- 720
P+ T +P KA PA S + P +S+ +K P + E+P
Sbjct: 798 DSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKK 857
Query: 721 ASQEVSTPSQAR--GEGSPSEATRLPTQGAR---------------------SSAAFPPK 757
A ++S A+ +GSP+ PT G S PK
Sbjct: 858 AQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPK 917
Query: 758 TSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGG---AAGPGEPVEVKEPPGLPAKPP 814
+ P + K +S+ + + ++ T + G +GPG P +K+ P P++PP
Sbjct: 918 SQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAP--MKQAPA-PSQPP 974
Query: 815 ASAQP 819
S P
Sbjct: 975 TSQGP 979
Score = 88.6 bits (218), Expect = 3e-17
Identities = 211/1009 (20%), Positives = 319/1009 (31%), Gaps = 139/1009 (13%)
Query: 199 PPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKW 258
PP SPS+ + PP PP P PA P + T T +
Sbjct: 72 PPAAAESPSMHRKQELDSSHPPKQSGRPPDPG--RPAQPGLSKSRTTDT----------F 119
Query: 259 KSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQ 318
+S+ L GR +S + K L+ + + + +
Sbjct: 120 RSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLI 179
Query: 319 EAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRA-PEPDCPGELKATAPASPRLG 377
EA ++E +K + P I+P Q P + P+ PG +P+
Sbjct: 180 SDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPK-- 237
Query: 378 QSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSS 437
SQ E+ + PP P P P LP + A+ P +
Sbjct: 238 SISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAK-----LPLQRDASRPQTKQADIVRGE 292
Query: 438 SPALKPKPNPPSPENTASSAPVDWRDPSQM---EKLRNELAAYLCGSRREDRFLSHRPGP 494
S KP+ PSP P + P+Q EK + A + L+ +PG
Sbjct: 293 SV----KPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGT 348
Query: 495 TVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTL---PSV 551
P G P PA+ P P GS +E L P V
Sbjct: 349 VKPPVQPPGTTKP-----------PAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGV 397
Query: 552 DYIPQDSPTPS---VRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDD 608
P P P+ +Q+ + AK + P + G+I A
Sbjct: 398 GKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPG 457
Query: 609 KLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPPKATLG 668
K S + P + + LP + P GPA PP P A PP PP G
Sbjct: 458 KTS--AQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPG 515
Query: 669 PATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTP 728
PA P G T P G A K S P KP++Q+ + P
Sbjct: 516 PAKPSPQQPGSTKPPSQQPGSA------------------KPSAQQPSPAKPSAQQSTKP 557
Query: 729 SQARGEGSPSE-------ATRLPTQGARSSAAFPPKTSPGGGEVP--------------- 766
G G P + A + P+QG + T+ VP
Sbjct: 558 VSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTV 617
Query: 767 ---CLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDEL 823
C + P+ H + + + + + G PV P L P + +
Sbjct: 618 CSLCGFNPNPHLTEVKEWLC--LNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKS 675
Query: 824 LRHPVTGEVVERGSPMALLLAARQRAQKGRSV------GAALGRSSLPGSLRDHSHQAEA 877
P + +P L A + + V G+ ++ P S A
Sbjct: 676 SPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPP 735
Query: 878 SSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRL------GRDAEGTELSR 931
S+ Q PK PK + + L + P + + E T
Sbjct: 736 KEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPL 795
Query: 932 RHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFS---SPPSPSN-----------KREEE 977
+ + KP P E+V+P + + P P S S S P PS+ +++EE
Sbjct: 796 KTDSAKPSQSFPPTGEKVSPFD-SKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEE 854
Query: 978 EEEFNFEVIPPP---PEFSNDPEPPAP---ALQYLGRQSSPPRNNYSDLRQLPNAG--PG 1029
++ ++ P P P P PP P A Q + P+ R N G
Sbjct: 855 PKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITD 914
Query: 1030 APPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGEPHRGPGLPHGGTGRSLSSP 1089
AP + P + G + G G S+ + + PG PH +G +P
Sbjct: 915 APKSQ-----PTTPQETVTG---KLFGFGASIFSQASNLISTAGQPG-PHSQSGP--GAP 963
Query: 1090 NCFGPQPGGPEMRR--VNSAGRAPPGGLHAPRLSLEGAARGAAEAKHKA 1136
P P P + S G+APP + + E A A + + KA
Sbjct: 964 MKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKA 1012
Score = 63.9 bits (154), Expect = 9e-10
Identities = 79/278 (28%), Positives = 102/278 (36%), Gaps = 77/278 (27%)
Query: 347 RPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPP 406
+PASQ+ P +P ++ PA PR S D A PPP PP PPP PP PPP
Sbjct: 2371 KPASQL-PSGSPSV-------SSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPP 2422
Query: 407 -APPLPP----------------AAP---------------------------------- 415
PPLPP A+P
Sbjct: 2423 PPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTA 2482
Query: 416 PLPCAQKAAHPPAG--FTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNE 473
P P K + P+G FT P+ S P + PKP P T + P D L +
Sbjct: 2483 PPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLP-TTTQKPTDIHPKPTGLSLTSS 2541
Query: 474 LAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPR----LPEKETLLSLPAKDTPPGVPE 529
+ L S D L P PT K PR L E +++LP++ PG P
Sbjct: 2542 MTLNLVTS--ADYKL---PSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSE---PGTPT 2593
Query: 530 KSLGGSSLTETE-AAPSLTLPSVDYIPQDSPTPSVRQI 566
S ++T +PS L SV+ P S P V +
Sbjct: 2594 DSSASQAITSWPLGSPSKDLVSVE--PVFSVVPPVTAV 2629
Score = 61.6 bits (148), Expect = 4e-09
Identities = 55/176 (31%), Positives = 65/176 (36%), Gaps = 23/176 (13%)
Query: 140 PPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPP---PPLLLEPPPPPSMAPPPPPVLEA 196
PPPPP P P PP PP P P PP T+P P P L P + A P +
Sbjct: 2407 PPPPPPPPPPPP-----PPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTT 2461
Query: 197 LSPPHTLSSPSIP------TPPDFIPPAPP-----LAFLAPPPPPVP--APAPPAPASPH 243
L L S +P T P +PP P L F P P P AP P P P
Sbjct: 2462 LETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPT 2521
Query: 244 TV--GTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLT 297
T T + P S + LN + + P SP P + P LT
Sbjct: 2522 TTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLT 2577
Score = 60.1 bits (144), Expect = 1e-08
Identities = 68/269 (25%), Positives = 91/269 (33%), Gaps = 72/269 (26%)
Query: 145 GPAPGPPQDISEPPGGSP----LPSPP-----------STAPPPPPLLLEPPPPPSMAPP 189
G G + S+ P GSP LP+ P S PPPPP PPPPP PP
Sbjct: 2364 GETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPP 2423
Query: 190 PPPVLEALSPPHTL--------SSPSIPTPPDFIP---------------PAPPLAFLAP 226
PPP+ SP T+ +SP P F P + AP
Sbjct: 2424 PPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP 2483
Query: 227 PP-PPVPAPAP--------PAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPP 277
PP PP P+ P P P+ P + P Q T P
Sbjct: 2484 PPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIP----------------QLPTTTQKPT 2527
Query: 278 RSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATK----- 332
+P G +L + +L +K+P P TS + + +PR + T+
Sbjct: 2528 DIHPKPTGLSLTSSMTLNLVTSADYKLPSP----TSPLSPHSNKSSPRFSKSLTETYVVI 2583
Query: 333 KAPSRLPLPPSFHIRPASQVYPDRAPEPD 361
PS P A +P +P D
Sbjct: 2584 TLPSEPGTPTDSSASQAITSWPLGSPSKD 2612
Score = 42.7 bits (99), Expect = 0.002
Identities = 81/353 (22%), Positives = 123/353 (34%), Gaps = 60/353 (16%)
Query: 567 RNELEARLSSAAEKEA-----KPSIGSLPPKPRLEGGRIC-------ENGADDDKLSKPV 614
+ ELEA + ++ E S+ +LP K +L E A P
Sbjct: 2323 KKELEAERTKSSLSETVFDHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPS 2382
Query: 615 AKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKAT--LWPATPPKATLGP--- 669
+LP + ++SL A P PP P P PP L P T PK T+ P
Sbjct: 2383 VSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKK 2442
Query: 670 ---------ATPL--KATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSG------ 712
ATPL T+ TT + ++G + TT P + SG
Sbjct: 2443 LTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHR 2502
Query: 713 --PAGQP--EKPASQEVSTPSQARGEGSPS----EATRLPTQGARSSAAF--PPKTSPGG 762
P+ P KP ++ T +Q + P T T +SA + P TSP
Sbjct: 2503 PEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSP-- 2560
Query: 763 GEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVE-------VKEPPGLPAKPPA 815
PH ++SS ++ + + PG P + P G P+K
Sbjct: 2561 ------LSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITSWPLGSPSKDLV 2614
Query: 816 SAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSL 868
S +P ++ PVT + S ++ + V A + P S+
Sbjct: 2615 SVEPVFSVV-PPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTSV 2666
Score = 32.7 bits (73), Expect = 2.1
Identities = 18/62 (29%), Positives = 26/62 (41%)
Query: 121 LYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEP 180
LYS + L PG+ + +P P P PQ + P P+ P TA + +P
Sbjct: 3623 LYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDP 3682
Query: 181 PP 182
P
Sbjct: 3683 KP 3684
Score = 32.0 bits (71), Expect = 3.6
Identities = 39/147 (26%), Positives = 48/147 (32%), Gaps = 29/147 (19%)
Query: 165 SPPSTAPPPPPLL------LEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIP-- 216
SPP P PL L +AP PP + L P + SP F+P
Sbjct: 3585 SPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKALESAFVPYE 3644
Query: 217 -PAP----PLAFLAPPPPPVPAPAP------------PAPASPHTVGTRLFP----PGGV 255
P P P L P VP +P P P SP + P G
Sbjct: 3645 KPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYT 3704
Query: 256 TKWKSDVALNGRQAEATRASPPRSPAE 282
TK + +G Q + R P P E
Sbjct: 3705 TKGSQTMTSSGAQKKVKRTLPNPPPEE 3731
>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
sapiens]
Length = 1636
Score = 107 bits (266), Expect = 9e-23
Identities = 111/396 (28%), Positives = 144/396 (36%), Gaps = 47/396 (11%)
Query: 126 GDLRPGQY-GQDLLIPPPPPGP-----APGPP--------QDISEPPGGSP----LPSPP 167
G L PG Y G LI P PGP APGP ++ P SP + SP
Sbjct: 789 GPLPPGTYSGPTQLIQPRAPGPHAMPVAPGPALYPAPAYTPELGLVPRSSPQHGVVSSPY 848
Query: 168 STAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPP 227
P PP+ P PP P + T+ S P P P P APP
Sbjct: 849 VGVGPAPPVAGLPSAPPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTP--APP 906
Query: 228 PPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSA 287
PP P P P +P+T P S G A P P A
Sbjct: 907 PPCFPVPPPQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQA 966
Query: 288 LGPNP--------EPHLTFPRS-FKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRL 338
GP P PHL P++ +PP +P + P Q P P++
Sbjct: 967 FGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPPLHT-QLYPGPAQD 1025
Query: 339 PLPPSFHIRPASQVYPDRAPEPDCP-GELKATAPASPRLGQSQSQADERAGTPPPAPPL- 396
PLP P P + P P G +T P P+ + AG P+P L
Sbjct: 1026 PLPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSPHLV 1085
Query: 397 PPPAP-PLPPPAPPLPPAAPPLPCAQKAA----------HPPAGFTKTPKSSSPALKPKP 445
P PAP P P P PP PPAA P PC ++ A G T++P P L+P
Sbjct: 1086 PSPAPSPGPGPVPPRPPAAEPPPCLRRGAAAADLLSSSPESQHGGTQSPGGGQPLLQPTK 1145
Query: 446 NPPSPENTASSAPVDWRD----PSQMEKLRNELAAY 477
+ + + RD P ++ +L+ EL A+
Sbjct: 1146 VDAAEGRRPQALRLIERDPYEHPERLRQLQQELEAF 1181
Score = 49.7 bits (117), Expect = 2e-05
Identities = 129/560 (23%), Positives = 166/560 (29%), Gaps = 162/560 (28%)
Query: 230 PVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPK--GSA 287
P P P P P P + +S+ G E R+ PP A P+ +
Sbjct: 716 PPPRPTAPKPLLPR-------------REESEAVEAGDPPEELRSLPPDMVAGPRLPDTF 762
Query: 288 LGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIR 347
LG H PP+P +S+ P P G PLPP +
Sbjct: 763 LGSATPLHF---------PPSPFPSSTGP------GPHYLSG---------PLPPGTYSG 798
Query: 348 PASQVYPDRAPEPDC----PGELKATAPA-SPRLGQSQSQADERAGTPPPAPPLPPPAPP 402
P + P RAP P PG APA +P LG + + P + P
Sbjct: 799 PTQLIQP-RAPGPHAMPVAPGPALYPAPAYTPELGLVPRSSPQHGVVSSPYVGVGPA--- 854
Query: 403 LPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWR 462
PP LP A PP + S P L P + + AP+
Sbjct: 855 --PPVAGLPSAPPP------------------QFSGPELAMAVRPATTTVDSIQAPI--- 891
Query: 463 DPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKD 522
PS + RP PT AP P P LP
Sbjct: 892 -PSHT---------------------APRPNPTPAPPPPCFPVPPPQP-------LPTPY 922
Query: 523 TPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEA 582
T P ++ + + P + PQ P P Q
Sbjct: 923 TYPAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQ----------------- 965
Query: 583 KPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKA----MLG 638
+ G PP+ L L P PPQ+ LLP S P A +LG
Sbjct: 966 --AFGPQPPQQPLP-------------LQHPHL--FPPQAPGLLPPQSPYPYAPQPGVLG 1008
Query: 639 PAIPPKAT---PEPAIPPKATLWPATP-----------PKATLGPATPLKATSGPTTPLK 684
PP T P PA P A P P GPA P GP
Sbjct: 1009 QPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGPPQPPHPPLAYGPA-PSTRPMGPQAAPL 1067
Query: 685 ATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLP 744
GP+ A +T P GP P PA++ P RG + + P
Sbjct: 1068 TIRGPSSAGQSTPSPHLVPSPAPSPGPGPV-PPRPPAAE--PPPCLRRGAAAADLLSSSP 1124
Query: 745 TQGARSSAAFPPKTSPGGGE 764
+ SPGGG+
Sbjct: 1125 ------ESQHGGTQSPGGGQ 1138
Score = 46.6 bits (109), Expect = 1e-04
Identities = 33/80 (41%), Positives = 38/80 (47%), Gaps = 10/80 (12%)
Query: 157 PPGG--SPLPSPPSTAPPP---PPLLLEPPPPPSMAPPP--PPVLEALSPPHTLSSPSIP 209
PPGG SP+ S P A PP P L E P PS +PPP P+ EA P P +P
Sbjct: 1509 PPGGLESPVASLPGPAEPPGLPPASLPESTPIPSSSPPPLSSPLPEA---PQPKEEPPVP 1565
Query: 210 TPPDFIPPAPPLAFLAPPPP 229
P PP+ L LA P
Sbjct: 1566 EAPSSGPPSSSLELLASLTP 1585
Score = 40.8 bits (94), Expect = 0.008
Identities = 107/459 (23%), Positives = 143/459 (31%), Gaps = 92/459 (20%)
Query: 442 KPKPNPPSPE----NTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLS-----HRP 492
KP P P +P+ S V+ DP E+LR+ + G R D FL H P
Sbjct: 715 KPPPRPTAPKPLLPRREESEAVEAGDPP--EELRSLPPDMVAGPRLPDTFLGSATPLHFP 772
Query: 493 GPTVAPQSK-------EGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPS 545
P+ P S G P T L P P +P G +L AP+
Sbjct: 773 -PSPFPSSTGPGPHYLSGPLPPGTYSGPTQLIQPRAPGPHAMPVAP--GPALYP---APA 826
Query: 546 LTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLP--PKPRLEGGRIC-- 601
T P + +P+ SP V S P + LP P P+ G +
Sbjct: 827 YT-PELGLVPRSSPQHGVVS---------SPYVGVGPAPPVAGLPSAPPPQFSGPELAMA 876
Query: 602 --ENGADDDKLSKPVAKNLPPQSTTL---------------LPTTSLQPKAMLGPAIP-- 642
D + P+ + P+ LPT P P IP
Sbjct: 877 VRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAKQP-IPAQ 935
Query: 643 -------PKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTA 695
P P P I P+ P P GP P + PL A
Sbjct: 936 HHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQ-------PLPLQHPHLFPPQA 988
Query: 696 TTLPTTTSQLMAEKDSGPAGQPEKPA-SQEVSTPSQARGEGSPSEATRLPTQGARSSAAF 754
L S G GQP P +Q P+Q + P+ + LP F
Sbjct: 989 PGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQ---DPLPAHSGALP---------F 1036
Query: 755 PPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARG-GAAGPGEPVEVKEPPGLPAKP 813
P P P Y P + + A P RG +AG P P P+
Sbjct: 1037 PSPGPPQPPHPPLAYGPAPSTRPMGPQAA---PLTIRGPSSAGQSTPSPHLVPSPAPSPG 1093
Query: 814 PASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKG 852
P P P + RG+ A LL++ +Q G
Sbjct: 1094 PGPVPPRPPAAEPP---PCLRRGAAAADLLSSSPESQHG 1129
Score = 40.4 bits (93), Expect = 0.010
Identities = 28/84 (33%), Positives = 35/84 (41%), Gaps = 6/84 (7%)
Query: 137 LLIPPP-----PPGPAPGPPQDISEPPGGSPLPSP-PSTAPPPPPLLLEPPPPPSMAPPP 190
L I PP P PGP + PP P +P PS++PPP L P P PP
Sbjct: 1505 LSIRPPGGLESPVASLPGPAEPPGLPPASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPV 1564
Query: 191 PPVLEALSPPHTLSSPSIPTPPDF 214
P + P +L + TP F
Sbjct: 1565 PEAPSSGPPSSSLELLASLTPEAF 1588
Score = 37.4 bits (85), Expect = 0.086
Identities = 25/71 (35%), Positives = 32/71 (45%), Gaps = 9/71 (12%)
Query: 388 GTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNP 447
G P LP PA P P LPPA+ P ++ PP + P+ A +PK P
Sbjct: 1512 GLESPVASLPGPAEP-----PGLPPASLPESTPIPSSSPPPLSSPLPE----APQPKEEP 1562
Query: 448 PSPENTASSAP 458
P PE +S P
Sbjct: 1563 PVPEAPSSGPP 1573
Score = 34.3 bits (77), Expect = 0.73
Identities = 33/117 (28%), Positives = 45/117 (38%), Gaps = 9/117 (7%)
Query: 304 VPPPT-PVRTSSIPVQE--AQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEP 360
VPPP P+ ++SI + Q++ G S IRP + +P
Sbjct: 1462 VPPPCKPLASASISQKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGL---ESPVA 1518
Query: 361 DCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLP-PPAPPLPPPAPPLPPAAPP 416
PG A P P +S + PP + PLP P P PP P P + PP
Sbjct: 1519 SLPGP--AEPPGLPPASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAPSSGPP 1573
Score = 33.1 bits (74), Expect = 1.6
Identities = 18/47 (38%), Positives = 24/47 (51%), Gaps = 1/47 (2%)
Query: 196 ALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASP 242
++ PP L SP P PP P A L P P+P+ +PP +SP
Sbjct: 1506 SIRPPGGLESPVASLPGPAEPPGLPPASL-PESTPIPSSSPPPLSSP 1551
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 105 bits (262), Expect = 3e-22
Identities = 202/850 (23%), Positives = 275/850 (32%), Gaps = 156/850 (18%)
Query: 5 QTVQGTFSKLFGKKHTTTPSTSLYATNPPWIFTQEAPEEGTGGF-------DGIYYGDNR 57
Q + L G TP+ SL T P + AP G+ G +
Sbjct: 1084 QVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAA 1143
Query: 58 FNTVSES-GTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVN 116
T S + TAT A P P L L+ P + EV L +
Sbjct: 1144 ATTTSTTTATATTTAVPAPTPAPQRLILS-----------PDMQARLPSGEVVSIGQLAS 1192
Query: 117 GNLRLYSSVGDLRP-------------GQYGQDLLIPPPPPGP-------APGPPQDISE 156
R ++ G +P G + L + P P + G +
Sbjct: 1193 LAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLIS 1252
Query: 157 PPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPP----PVLEALSPPHTLSSPSIPTPP 212
P L + P P P+ + P PS P P P+ PP +++ +
Sbjct: 1253 QPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVK-- 1310
Query: 213 DFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEAT 272
+ P L P PP PAP PP+ P + R
Sbjct: 1311 -IVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPR-----------------------P 1346
Query: 273 RASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIP------VQEAQEAPRK 326
+P R P G+A P P P L P V P+P ++S P + P
Sbjct: 1347 TLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSS 1406
Query: 327 EEGATKKAPSRLPLPPSFHIR---------PASQVYPDRAPEP-DCPGELKATAPASPRL 376
G A S +P+P S + P S P P P T P S L
Sbjct: 1407 LPGP---ASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPL 1463
Query: 377 GQSQSQADERAGTPPPAPPLPP--PAPPLPPPAPPLPPA---------APPLPCAQKAAH 425
S S PP P+ P P PP P+ P A AP L +Q H
Sbjct: 1464 TVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGH 1523
Query: 426 P----------PAGFTKTPKSSSPALKP-----KPNPPSPENTASSAPVDWRDPSQMEKL 470
P P + + SP L P P P +P + A + S + L
Sbjct: 1524 PLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQAL 1583
Query: 471 RNELAAYLCGSRREDRFLSHRPGPTVAPQ---SKEGKKGPRLPEKETLLSLPAKDTPPGV 527
LA + + L+ P P +AP + P L +T + + A + PG
Sbjct: 1584 ATPLAPM---AAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGT 1640
Query: 528 PEKSLGGSSLTETEAAPSLT---LPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKP 584
S APS T LP+ +P P+P+ Q + A P
Sbjct: 1641 SLASASPVPAPTPVLAPSSTQTMLPAP--VPSPLPSPASTQ---------TLALAPALAP 1689
Query: 585 SIGSLPPKPRLEGGRICENGA-DDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPP 643
++G P L G G LS A +L P T T SL P LGP
Sbjct: 1690 TLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVP---TPAQTLSLAPGPPLGPTQTL 1746
Query: 644 KATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTS 703
P P + P + + PA TL PA+ + P + T PA TL +
Sbjct: 1747 SLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPA---PVPTLGPAAA 1803
Query: 704 QLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEAT---RLP-------TQGARSSAA 753
Q +A PA + PASQ S A G +P T RLP T RS
Sbjct: 1804 QTLA---LAPA-STQSPASQASSLVVSASG-AAPLPVTMVSRLPVSKDEPDTLTLRSGPP 1858
Query: 754 FPPKTSPGGG 763
PP T+ G
Sbjct: 1859 SPPSTATSFG 1868
Score = 101 bits (252), Expect = 4e-21
Identities = 201/848 (23%), Positives = 289/848 (34%), Gaps = 124/848 (14%)
Query: 134 GQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSP-----PSTAPPPPPLLLEPPPPP--SM 186
G L+ PPGP PP + LPSP ++ PP P L L+P PP +
Sbjct: 1057 GPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRL 1116
Query: 187 APPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVG 246
+P PPP +L P T+ P + A P P PAP +
Sbjct: 1117 SPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQ 1176
Query: 247 TRLFPPGGVTKWKSDVALNGRQAEATRASPP-----------RSPAEPKGSALGPNPEP- 294
RL P G V +L R S P + A+ + A+G P P
Sbjct: 1177 ARL-PSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVG-QPRPL 1234
Query: 295 -----HLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHI-RP 348
HL P + I P PS P P +
Sbjct: 1235 QRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLA 1294
Query: 349 ASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPP--- 405
A+QV P + G +K +PR D PP AP PP+ LP
Sbjct: 1295 ANQVPPTMV---NNTGVVKIVVRQAPR--------DGLTPVPPLAPAPRPPSSGLPAVLN 1343
Query: 406 PAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTAS---SAPVDWR 462
P P L P P P A P TP P LK + PSPE +AS +AP+
Sbjct: 1344 PRPTLTPGRLPTPTLGTARAP----MPTPTLVRPLLK-LVHSPSPEVSASAPGAAPLTIS 1398
Query: 463 DPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETL-LSLPAK 521
P + A+ S P P +P + +P +L +S+P
Sbjct: 1399 SPLHVPSSLPGPAS------------SPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTT 1446
Query: 522 -DTPPGVPEKSLGGSSLTETEAAP----SLTLPSVDYIPQDSPTPSVRQIRNELEARLSS 576
P P + LT + + P S+T P +P PS+ S
Sbjct: 1447 LPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSL----------APS 1496
Query: 577 AAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTS--LQPK 634
A A L P L + L P + ++P ++T+ P S L P
Sbjct: 1497 GASPSASALTLGLATAPSLSSSQT----PGHPLLLAPTSSHVPGLNSTVAPACSPVLVPA 1552
Query: 635 AMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATS------- 687
+ L P + P PA + L PA+ L ATPL + P T + A S
Sbjct: 1553 SALASPFP--SAPNPAPAQASLLAPASSASQAL--ATPLAPMAAPQTAILAPSPAPPLAP 1608
Query: 688 ----------GPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSP 737
P +AS+ T +P + + A PA V PS +
Sbjct: 1609 LPVLAPSPGAAPVLASSQTPVPVMAPS--STPGTSLASASPVPAPTPVLAPSSTQTMLPA 1666
Query: 738 SEATRLPTQGARSSAAFPPKTSPG-GGEVPCL---------YKPHCHQSSLSREVAVVMP 787
+ LP+ + + A P +P GG P P Q+ + ++P
Sbjct: 1667 PVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVP 1726
Query: 788 TLARGGAAGPGEPVEVKEPPGL-PAKPPASAQPTDELLRHPVTGEVVERGSPMALLLAAR 846
T A+ + PG P+ + L PA P A A P H +T + S +LL A
Sbjct: 1727 TPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLT--LAPASSSASLLAPAS 1784
Query: 847 QRA-----QKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKE 901
+ ++G A ++ S ++ASS + S P T+V +LP
Sbjct: 1785 VQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVS 1844
Query: 902 AEKDSPLT 909
++ LT
Sbjct: 1845 KDEPDTLT 1852
Score = 85.9 bits (211), Expect = 2e-16
Identities = 150/633 (23%), Positives = 211/633 (33%), Gaps = 95/633 (15%)
Query: 139 IPPPPPGPAPGPPQDISEPPGGSPLPSP---PSTAPPP----PPLLLEPPPPPSMAPPPP 191
+P P P P P P + P P+P P +AP P P +L PPPPS PP
Sbjct: 2436 VPRPAPRPRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPPSQIPPCS 2495
Query: 192 PVLEALSPPHTLSSPSIPTPPD----FIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGT 247
A +PP + P TPP + P+ PL L PP P+ A P
Sbjct: 2496 S--PACTPPPACTPPPAHTPPPAQTCLVTPSSPL-LLGPPSVPISASVTNLPLGLRP-EA 2551
Query: 248 RLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPP 307
L + ++A ++ + P P + P E +L+ S P
Sbjct: 2552 ELCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPS---APS 2608
Query: 308 TPVRTSSIPVQEAQEAPRKEEGATKKA-PSRLPLPPSFHIRPASQVYPDRAPEPDCPGEL 366
+ SIP + QEAP EG T P LP ++ P A + L
Sbjct: 2609 LTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPL 2668
Query: 367 KATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHP 426
+A S+ A TP +P P AP +A P A P
Sbjct: 2669 EA---------DRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARP 2719
Query: 427 PAGFTKTPKSSSPALKPKP-NPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRRED 485
P T +P PP P+ V + P ++ + E L RR+
Sbjct: 2720 PRRRTSADVEIRGQGTGRPGQPPGPK-------VLRKLPGRLVTVVEE--KELVRRRRQQ 2770
Query: 486 RFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPS 545
R T+ P E P P + +S P P G P EAAPS
Sbjct: 2771 R----GAASTLVPGVSETSASPGSPSVRS-MSGPESSPPIGGP-----------CEAAPS 2814
Query: 546 LTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGR------ 599
+LP+ P P + R I EL + E + PP + GR
Sbjct: 2815 SSLPT----PPQQPFIARRHI--ELGVTGGGSPENGDGALLAITPPAVKRRRGRPPKKNR 2868
Query: 600 ---ICENGADDDKLSKPVAKN-----LPPQSTTLLPTTSLQPKAMLGP---AIPPKATPE 648
G D+ S K +P T ++ L+P+ + GP P P
Sbjct: 2869 SPADAGRGVDEAPSSTLKGKTNGADPVPGPETLIVADPVLEPQLIPGPQPLGPQPVHRPN 2928
Query: 649 PAIPPKATLWPATPPKATLGPATPLKATSG------------------PTTPLKATSGPA 690
P + P PPKA P +++G P PL
Sbjct: 2929 PLLSPVEKRRRGRPPKARDLPIPGTISSAGDGNSESRTQPPPHPSPLTPLPPLLVCPTAT 2988
Query: 691 IASTATTLPTTTSQLMAEKDSGPAGQPEKPASQ 723
+A+T TT+ +TS ++ P P SQ
Sbjct: 2989 VANTVTTVTISTSPPKRKRGRPPKNPPSPRPSQ 3021
Score = 70.9 bits (172), Expect = 7e-12
Identities = 144/558 (25%), Positives = 199/558 (35%), Gaps = 81/558 (14%)
Query: 305 PPPTPVRTSSIPVQEAQEAPRKEEGATKKAPS--RLPLPPSFHIRPASQVYPDRAPEPDC 362
PPP P + + V + K+EG T + R PL P +RP P+ + +P
Sbjct: 983 PPPRP-KPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGP-VPVRPPPG--PELSAQPT- 1037
Query: 363 PGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPA-PPLPPPAPPLPPAAPPLPCAQ 421
PG + PAS + S P PPL P + PP P PPL P + LP Q
Sbjct: 1038 PGPVPQVLPASLMVSAS-----------PAGPPLIPASRPPGPVLLPPLQPNSGSLP--Q 1084
Query: 422 KAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLR---------- 471
P + T + +P L KP PP+P + + P P L+
Sbjct: 1085 VLPSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPP-----PGSSSLLKPLTVPPGYTF 1139
Query: 472 NELAAYLCGSRREDRFLSHRPGPTVAPQS--KEGKKGPRLPEKETLLSLPAKDTPPGVPE 529
AA + + P PT APQ RLP E ++S+ + P
Sbjct: 1140 PPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGE-VVSIGQLASLAQRPV 1198
Query: 530 KSLGGSS-LTETEAAPSLTL--PSVDYIPQDSPTPSVRQIRNELEA-----RLSSAAEKE 581
+ GGS LT LTL V + P P R + + + A +S A
Sbjct: 1199 ANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVA 1258
Query: 582 AKPSIGSLP---PKPRLEGGRICENGADDDKLSKPVAKNLPPQS-----------TTLLP 627
++ P P L A LS P+A N P + P
Sbjct: 1259 LIQAVAPTPGPTPVSVLPSSTPSTTPAPTG-LSLPLAANQVPPTMVNNTGVVKIVVRQAP 1317
Query: 628 TTSLQPKAMLGPAIPPKATPEPAI-PPKATLWPATPPKATLGPA---TPLKATSGPTTPL 683
L P L PA P ++ PA+ P+ TL P P TLG A P P L
Sbjct: 1318 RDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKL 1377
Query: 684 KATSGPAIASTAT-TLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATR 742
+ P ++++A P T S + S P PAS + P+ + S
Sbjct: 1378 VHSPSPEVSASAPGAAPLTISSPLHVPSSLPG-----PASSPMPIPNSSPLASPVSSTVS 1432
Query: 743 LPTQGARSSAAFPPKTSPGGGEVPC---LYKPHCHQSSLSREVAVVMPTLARGGAAGPGE 799
+P + + P T P P + P +S + V P LA A PG
Sbjct: 1433 VPLSSSLPISV--PTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGP 1490
Query: 800 PVEVKEPPGLPAKPPASA 817
P P G A P ASA
Sbjct: 1491 P--SLAPSG--ASPSASA 1504
Score = 60.1 bits (144), Expect = 1e-08
Identities = 145/615 (23%), Positives = 215/615 (34%), Gaps = 128/615 (20%)
Query: 348 PASQVYPDRAPEPDCPGELKATAPAS-PRLGQSQSQADERAGTPPPAPPLPPPAPPLPPP 406
PA + P AP P A+APA+ P L A P P LP P PPP
Sbjct: 2431 PARERVPRPAPRPR---PTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPP 2487
Query: 407 APPLPPAA-----PPLPCAQKAAH-PPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVD 460
+PP + PP C AH PP T SSP L P+ P + ++ P+
Sbjct: 2488 PSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPI-SASVTNLPLG 2546
Query: 461 WRDPSQM--EKLRNELAAYLCG-SRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLS 517
R +++ + L + + L + E LS P + P + E LP E LS
Sbjct: 2547 LRPEAELCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVE-----ILPVSEKNLS 2601
Query: 518 LPAKDTPPGVPEKSLGGSSL---TETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARL 574
L P P +L S+ E EA S ++ +P+ P N LE
Sbjct: 2602 L-----TPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPP 2656
Query: 575 SSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPK 634
S+A+++ P + LE R E +L++ P+ L T +
Sbjct: 2657 SAASDE---------PLQEPLEADRTSE------ELTEAKTPTSSPEKPQELVTAEVAAP 2701
Query: 635 AMLGPAIPPKATPEPAIPPK------------ATLWPATPPKATLGPATPLKATSGPTTP 682
+ A P PA PP+ T P PP GP K T
Sbjct: 2702 STSSSATSSPEGPSPARPPRRRTSADVEIRGQGTGRPGQPP----GPKVLRKLPGRLVTV 2757
Query: 683 LK---------------ATSGPAIASTATTLPTTTSQLMAEKDSGP--AGQPEKPASQEV 725
++ +T P ++ T+ + + + + M+ +S P G E S +
Sbjct: 2758 VEEKELVRRRRQQRGAASTLVPGVSETSASPGSPSVRSMSGPESSPPIGGPCEAAPSSSL 2817
Query: 726 STPSQ------------ARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHC 773
TP Q G GSP GA A PP G P K +
Sbjct: 2818 PTPPQQPFIARRHIELGVTGGGSPENG-----DGA-LLAITPPAVKRRRGRPP---KKNR 2868
Query: 774 HQSSLSREVAVVMPTLARGGAAGPGEPV----------EVKEPPGLPAKPPASAQPTDEL 823
+ R V + +G G +PV V EP +P P QP
Sbjct: 2869 SPADAGRGVDEAPSSTLKGKTNG-ADPVPGPETLIVADPVLEPQLIPGPQPLGPQP---- 2923
Query: 824 LRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIF 883
V R +P LL+ ++ ++GR A +PG++ S + +S+S
Sbjct: 2924 ---------VHRPNP---LLSPVEKRRRGRPPKAR--DLPIPGTI---SSAGDGNSESRT 2966
Query: 884 HSQGTPNSFTVVPKL 898
P+ T +P L
Sbjct: 2967 QPPPHPSPLTPLPPL 2981
Score = 59.3 bits (142), Expect = 2e-08
Identities = 80/285 (28%), Positives = 99/285 (34%), Gaps = 57/285 (20%)
Query: 139 IPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALS 198
+P P P AP Q + P SPLPSP ST ++AP P L S
Sbjct: 1648 VPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTL------------ALAPALAPTLGGSS 1695
Query: 199 PPHTLS----SPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGG 254
P TLS +P P P + L P VP PA +P PP G
Sbjct: 1696 PSQTLSLGTGNPQGPFPTQTLS-------LTPASSLVPTPAQTLSLAPG-------PPLG 1741
Query: 255 VTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTF-PRSFKVPPPTPVRTS 313
T Q + +PP +PA P +GP P LT P S P +
Sbjct: 1742 PT-----------QTLSLAPAPPLAPASP----VGPAPAHTLTLAPASSSASLLAP---A 1783
Query: 314 SIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPAS 373
S+ AP G A L L P+ PASQ + G
Sbjct: 1784 SVQTLTLSPAPVPTLGPA--AAQTLALAPASTQSPASQA---SSLVVSASGAAPLPVTMV 1838
Query: 374 PRLGQSQSQADE---RAGTPPPAPPLPPPAPPLPPPAPPLPPAAP 415
RL S+ + D R+G P P P P PP PP +P
Sbjct: 1839 SRLPVSKDEPDTLTLRSGPPSPPSTATSFGGPRPRRQPPPPPRSP 1883
Score = 54.7 bits (130), Expect = 5e-07
Identities = 120/529 (22%), Positives = 174/529 (32%), Gaps = 87/529 (16%)
Query: 264 LNGRQAEATRASPPRSPAEPKGSALGPNPEP-HLTFPRSFKVPPPTPVRTSSIPVQEAQE 322
++ Q +T P SPA + P P P + P + P PV S PV +
Sbjct: 2415 ISAHQTRSTTTPPRCSPARERVPRPAPRPRPTPASAPAAIPALVPVPV---SAPVPISAP 2471
Query: 323 APRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQ 382
P T LP PP P SQ+ P P C T P
Sbjct: 2472 NP-----ITILPVHILPSPP-----PPSQIPP--CSSPACTPPPACTPPP---------- 2509
Query: 383 ADERAGTPPPAPP-LPPPAPP--LPPPAPPLPPAAPPLP---------CAQKAAHPP--- 427
A TPPPA L P+ P L PP+ P+ + LP CAQ A P
Sbjct: 2510 ----AHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCAQALASPESLE 2565
Query: 428 -AGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDR 486
A + SS + PK P + + L E + G +E
Sbjct: 2566 LASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQE-- 2623
Query: 487 FLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTE-TEAAPS 545
AP S EG LPE E L ++ +P + L E EA +
Sbjct: 2624 ----------APDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRT 2673
Query: 546 LTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGA 605
+ P SP + E+ A +S++ + P R + G
Sbjct: 2674 SEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVEIRGQ 2733
Query: 606 DDDKLSKP----VAKNLPPQSTTLLPTTSL--QPKAMLGPAIPPKATPEPAIPPKATLWP 659
+ +P V + LP + T++ L + + G A +TL P
Sbjct: 2734 GTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAA--------------STLVP 2779
Query: 660 ATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLM-----AEKDSGPA 714
+ + +++ SGP + GP A+ +++LPT Q E
Sbjct: 2780 GVSETSASPGSPSVRSMSGPESS-PPIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTGG 2838
Query: 715 GQPEK--PASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPG 761
G PE A ++ P+ R G P + R P R P T G
Sbjct: 2839 GSPENGDGALLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKG 2887
Score = 52.0 bits (123), Expect = 3e-06
Identities = 135/615 (21%), Positives = 196/615 (31%), Gaps = 148/615 (24%)
Query: 82 LPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNLRLYSSVGDLRPGQYGQDLLIPP 141
LPL E++GL +P + D+ + + + + L
Sbjct: 2642 LPLCVSESNGLELPPSAASDEPLQEPLEADRT---------------------SEELTEA 2680
Query: 142 PPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMA-------------- 187
P +P PQ++ +P S +T+ P P PP + A
Sbjct: 2681 KTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVEIRGQGTGRPGQ 2740
Query: 188 PPPPPVLEAL-----------------------------SPPHTLSSPSIPTPPDFIPP- 217
PP P VL L T +SP P+ P
Sbjct: 2741 PPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPGVSETSASPGSPSVRSMSGPE 2800
Query: 218 -APPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSD---VALNGRQAEATR 273
+PP+ P P PP L GG + D +A+ + R
Sbjct: 2801 SSPPIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTGGGSPENGDGALLAITPPAVKRRR 2860
Query: 274 ASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSI---PVQEAQEAPRKEEGA 330
PP+ P + G + P T P P + I PV E Q P +
Sbjct: 2861 GRPPKKNRSPADAGRGVDEAPSSTLKGKTNGADPVPGPETLIVADPVLEPQLIPGPQPLG 2920
Query: 331 TKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTP 390
+ P P P + + P +A + PG + + G S+S+ T
Sbjct: 2921 PQ--PVHRPNPLLSPVEKRRRGRPPKARDLPIPGTISSAGD-----GNSESR------TQ 2967
Query: 391 PPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALK---PKPNP 447
P PP P P PL PPL A T T +S P K P NP
Sbjct: 2968 P--PPHPSPLTPL-----------PPLLVCPTATVANTVTTVTISTSPPKRKRGRPPKNP 3014
Query: 448 PSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGP 507
PSP S PV RD + + L + G RR+ + G + S + G
Sbjct: 3015 PSPR--PSQLPVLDRDSTSV------LESCGLGRRRQPQ------GQGESEGSSSDEDGS 3060
Query: 508 RLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIR 567
R + L L A+ G+ + GGS + V I+
Sbjct: 3061 RPLTRLARLRLEAE----GMRGRKSGGSMV-------------------------VAVIQ 3091
Query: 568 NELEARLSSAAEKEAKPSIGSLPPK---PRLEGGRICENGADDDKLSKPVAKNLPPQSTT 624
++L+ S E P + SL PK RL G + + +KL + A S
Sbjct: 3092 DDLDLADSGPGGLELTPPVVSLTPKLRSTRLRPGSLVP-PLETEKLPRKRAGAPVGGSPG 3150
Query: 625 LLPTTSLQPKAMLGP 639
L LQP + LGP
Sbjct: 3151 LAKRGRLQPPSPLGP 3165
Score = 42.0 bits (97), Expect = 0.003
Identities = 115/495 (23%), Positives = 164/495 (33%), Gaps = 104/495 (21%)
Query: 711 SGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYK 770
S A PE+P ++ AR E + T + + S PP+ SP VP
Sbjct: 2382 SKKAKAPERPGTRVSERLRGARAETQGANHTPVISAHQTRSTTTPPRCSPARERVP---- 2437
Query: 771 PHCHQSSLSREVAVVMPTLARGGAAGPG-EPVEVKEPPGLPAKPPASAQPTDELLRHPVT 829
R PT A AA P PV V P + A P + P L P
Sbjct: 2438 ---------RPAPRPRPTPASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSPPPP 2488
Query: 830 GEVVERGSP--------------------MALLLAARQRAQKGRSVGAALGRSSLPGSLR 869
++ SP L+ + SV + ++LP LR
Sbjct: 2489 SQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLR 2548
Query: 870 DHSH---QAEASSDSI---FHSQGTPNSFTVVPKLPKEAEKDSPLTTEI--PNKWGPRLG 921
+ QA AS +S+ + +S ++VP PK+ P+ EI ++ L
Sbjct: 2549 PEAELCAQALASPESLELASVASSETSSLSLVP--PKDL---LPVAVEILPVSEKNLSLT 2603
Query: 922 RDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSS------PPS------ 969
A L E +AP + E + LP+G LP S PPS
Sbjct: 2604 PSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEP 2663
Query: 970 -------------------PSNKREEEEEEFNFEVIPPPPEFS--NDPEPPAPALQYLGR 1008
P++ E+ +E EV P S + PE P+PA
Sbjct: 2664 LQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPA------ 2717
Query: 1009 QSSPPRNNYS---DLRQLPNAGPGAPPALGFSRFPAGARYAGAGGLE------RFSGGGR 1059
PPR S ++R PG PP R G E + G
Sbjct: 2718 --RPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAAS 2775
Query: 1060 SLIKKRLYVGEPHRGPGLPHGGTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPGGLHAPR 1119
+L+ V E PG P + RS+S P P GGP +S+ PP R
Sbjct: 2776 TLVPG---VSETSASPGSP---SVRSMSGPES-SPPIGGPCEAAPSSSLPTPPQQPFIAR 2828
Query: 1120 LSLEGAARGAAEAKH 1134
+E G ++
Sbjct: 2829 RHIELGVTGGGSPEN 2843
Score = 32.0 bits (71), Expect = 3.6
Identities = 37/148 (25%), Positives = 56/148 (37%), Gaps = 25/148 (16%)
Query: 679 PTTPLKATSGPAI-ASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSP 737
P T KA S P + +S+A + P + + ++D Q ++ E + + + EG+
Sbjct: 254 PLTSSKAGSSPCLGSSSAASSPPPPASRLDDEDGDFQPQEDEEEDDEETIEVEEQQEGND 313
Query: 738 SEATRLPTQGARSSAAFP--------PKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTL 789
+EA R + R P P G P P H S +R+
Sbjct: 314 AEAQRREIELLRREGELPLEELLRSLPPQLLEGPSSPS-QTPSSHDSD-TRD-------- 363
Query: 790 ARGGAAGPGEPVEVKEPPGLPAKPPASA 817
GP E E + P L KPP SA
Sbjct: 364 ------GPEEGAEEEPPQVLEIKPPPSA 385
Score = 30.8 bits (68), Expect = 8.0
Identities = 37/150 (24%), Positives = 51/150 (34%), Gaps = 13/150 (8%)
Query: 83 PLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNLRLYSSVGDLRPGQYGQDLLIPPP 142
PL + LA P P T +L + SS L P L P P
Sbjct: 1739 PLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPAS----SSASLLAPASVQTLTLSPAP 1794
Query: 143 PPGPAPGPPQDISEPPGGSPLPSPPSTA-------PPPPPLLLEPPPPPSMAPPPPPVLE 195
P P Q ++ P + P+ +++ P P+ + P S P L
Sbjct: 1795 VPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLR 1854
Query: 196 A--LSPPHTLSSPSIPTPPDFIPPAPPLAF 223
+ SPP T +S P P PP P F
Sbjct: 1855 SGPPSPPSTATSFGGPRPRRQPPPPPRSPF 1884
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 103 bits (257), Expect = 1e-21
Identities = 118/456 (25%), Positives = 168/456 (36%), Gaps = 73/456 (16%)
Query: 134 GQDLLIPPPPPGPAPGPPQD------ISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMA 187
G ++ +P P P P PP + S + PSP + P L+ P S++
Sbjct: 175 GTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 234
Query: 188 PPPPPVLE-ALSPPHTLSSPSIPT--------------PPDFIPP----APPLAFLAPPP 228
P+ A S P +P P PP PP AP L L+ P
Sbjct: 235 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 294
Query: 229 PPVPAP-APPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSA 287
P+P APP+P++P ++ T PP ++ +L +AT + P P P +
Sbjct: 295 LATPSPSAPPSPSAPPSLQTLPSPPATPPS-QATTSLGSPTLQATHSFLPSPPLSPLATP 353
Query: 288 LGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIR 347
PP P + P+Q AP + +P P P + +
Sbjct: 354 -----------------PPQAPPALALPPLQ----APPSPPASPPLSPLATPSPQAPNAL 392
Query: 348 PASQVYPDRAPEPDCPGELKATAPASPRLGQSQ---SQADERAGTPP-PAPPLPPPAPPL 403
+ +P P P + + PASP + S SQA PP PP PP +PP+
Sbjct: 393 AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 452
Query: 404 PPPAPPLPPAAPPL--PCAQKAAHPPAGFTKTPKSSSPALKPKPNPP---------SPEN 452
P A P P A PPL P Q A PP P ++P L+ P+PP SP
Sbjct: 453 SPSATPPPQAPPPLAAPPLQLAKPPPQA---PPALATPPLQALPSPPASFPGQAPFSPSA 509
Query: 453 TASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEK 512
+ +P+ P L L + R PT P + GPRL
Sbjct: 510 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT--SVSGPRL--- 564
Query: 513 ETLLSLPAKDTPPG-VPEKSLGGSSLTETEAAPSLT 547
TL P PP P +L G L ++ + T
Sbjct: 565 -TLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATST 599
Score = 99.8 bits (247), Expect = 1e-20
Identities = 199/797 (24%), Positives = 262/797 (32%), Gaps = 189/797 (23%)
Query: 130 PGQYGQDLLIPPPPPGPAPGPP-----------------QDISEPPGGSPLPSPPSTAPP 172
P LL P PP P P PP + ++E GG + P +AP
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 173 PPPLLLEPPP--------PPSMAPPPPPVLE------------------ALSPPHTLS-- 204
P PP PP+ P PV +S T++
Sbjct: 77 AGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARG 136
Query: 205 -----------------SPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGT 247
S PTP P + A +P PAP A P T G
Sbjct: 137 KATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGP 196
Query: 248 R----------LFPPGGVTKWKSDVALNGRQAEATR-----ASPPRSPAEPKGSALG-PN 291
R P + + A G Q A+R A+P SPA SA G P
Sbjct: 197 RKSVSSASEHSTTEPSPAAR-RRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPR 255
Query: 292 PEPHLTFPR-----SFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHI 346
H + P+ + + P TP R + P P +PS PPS
Sbjct: 256 APAHPSQPKPKGLQALRPPQVTPPRKDAAPAL----GPLSSSPLATPSPS---APPSPSA 308
Query: 347 RPASQVYPDRAPEPDCPGELKATAPASPRLGQSQS-----QADERAGTPPPAPP---LPP 398
P+ Q P P P T+ SP L + S A PP APP LPP
Sbjct: 309 PPSLQTLPS---PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP 365
Query: 399 -PAPPLPPPAPPLPPAAPPLPCAQKA----------AHPPAGFTKTPKS--SSPALKPKP 445
APP PP +PPL P A P P A A + PP+ + P S +SP + P
Sbjct: 366 LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA 425
Query: 446 NPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKK 505
PPS + +AP PS +A P P AP + K
Sbjct: 426 TPPSQAPPSLAAPPLQVPPSPPASPPMSPSA---------TPPPQAPPPLAAPPLQLAKP 476
Query: 506 GPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQ 565
P+ P PA TPP S S + +PS +LP P +P P
Sbjct: 477 PPQAP--------PALATPPLQALPSPPASFPGQAPFSPSASLP---MSPLATPPPQAPP 525
Query: 566 IRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKP----VAKNLPPQ 621
+ L A L S P P L+ R D +S P PP
Sbjct: 526 V---LAAPLLQVPP--------SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 574
Query: 622 STTLLPTTSLQPKAMLGPAIPPKATPE--------------PAIPPKATLWPATPPKATL 667
+ P+++L + G + +TPE + PP A L P +
Sbjct: 575 PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR 634
Query: 668 GPATPLKATSGPTTPL--KATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEV 725
GPA PL P PL +GP A T+ T GP E
Sbjct: 635 GPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYET---------EGP----------ES 675
Query: 726 STPSQARGEGSPSEATR--LPTQGARSSAAFPPKTSPGGGEVPC-LYKPHCHQSSLSREV 782
+TP+ + PS T GA + A+ GE+P + Q LSR +
Sbjct: 676 ATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTL 735
Query: 783 AVVMPTLARGGA-AGPG 798
+ A GG+ GPG
Sbjct: 736 LLAAAEGAAGGSGGGPG 752
Score = 97.1 bits (240), Expect = 9e-20
Identities = 134/489 (27%), Positives = 174/489 (35%), Gaps = 59/489 (12%)
Query: 129 RPGQYGQDLLIPPP--PP----GPAPGPPQDISEPPGGSPLPS-------PPSTAPPPPP 175
+P G L PP PP PA GP +S P +P PS PPS P P
Sbjct: 262 QPKPKGLQALRPPQVTPPRKDAAPALGP---LSSSPLATPSPSAPPSPSAPPSLQTLPSP 318
Query: 176 LLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPA 235
P PPS A +L SP++ F+ P+PPL+ LA PPP P PA
Sbjct: 319 ----PATPPSQATT------------SLGSPTLQATHSFL-PSPPLSPLATPPPQAP-PA 360
Query: 236 ---PPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAE-----PKGSA 287
PP A P + P ++ AL +A + PP P + P
Sbjct: 361 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 420
Query: 288 LGPNPEPHLTFPRSFKVPP--PTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFH 345
+ P+ P P S PP P +S P+ + P + P +L PP
Sbjct: 421 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP-- 478
Query: 346 IRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPP 405
P + P P P AP SP S S TPPP P AP L
Sbjct: 479 QAPPALATPPLQALPSPPASFPGQAPFSP----SASLPMSPLATPPPQAPPVLAAPLL-- 532
Query: 406 PAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPP---SPENTASSAPVDWR 462
PP PPA+P L ++ P + + + AL P P PP SP +T S +
Sbjct: 533 QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGH 592
Query: 463 DPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLP-EKETLLSLPAK 521
S EL Y G A +GP P P
Sbjct: 593 S-SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLP 651
Query: 522 DTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKE 581
P P + G ++ ETE S T P SP S + A SS + K+
Sbjct: 652 WPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQ 711
Query: 582 AKPSIGSLP 590
A+ +G LP
Sbjct: 712 AR--LGELP 718
Score = 92.4 bits (228), Expect = 2e-18
Identities = 190/719 (26%), Positives = 247/719 (34%), Gaps = 121/719 (16%)
Query: 146 PAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSS 205
PA P ++ P GSP P PP T P L P A
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVT-----PAALRVLGAAGAVGRKPLAERAGGIGGATIP 71
Query: 206 PSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVG--TRLFPPG--GVTKWKSD 261
S P PP + PP +P +SP TR P G G+ +
Sbjct: 72 ESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEE 131
Query: 262 VALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQ 321
G+ EA + S + A S GP P P P R S
Sbjct: 132 TVARGKATEAPKRSALSAGARRDTS--GPTP----------GTPSPAMARRS-------- 171
Query: 322 EAPRKEEGATKKAPSRLPLPPSFHIRPA-SQVYPDRAPEPDCPGELKATA------PASP 374
A E G + APS P PP+ R + S EP + +A PAS
Sbjct: 172 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 231
Query: 375 RLGQSQSQADERAGTPPPAPPLP-PPAPPLPPPAPPLPPAAPP-LPCAQKAAHPPAGFTK 432
L S + A + P A P PA P P L PP + +K A P G
Sbjct: 232 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALG--- 288
Query: 433 TPKSSSPALKPKPN-PPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHR 491
P SSSP P P+ PPSP SAP + A GS S
Sbjct: 289 -PLSSSPLATPSPSAPPSP-----SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFL 342
Query: 492 PGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSV 551
P P ++P + P+ P L L A +PP P S + + A ++ L
Sbjct: 343 PSPPLSPLA---TPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQA 399
Query: 552 DYIPQDSPTPSVRQIRNELEARLSSAA--EKEAKPSIGS----LPPKPRLEGGRICENGA 605
+ P SP P +S +A +A PS+ + +PP P + +
Sbjct: 400 PFSPPPSP-PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP-ASPPMSPSAT 457
Query: 606 DDDKLSKPVA------KNLPPQSTTLLPTTSLQ-----PKAMLGPA---------IPPKA 645
+ P+A PPQ+ L T LQ P + G A + P A
Sbjct: 458 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 517
Query: 646 TPEPAIPPKATL----WPATPPKATLGPATPLKATSGPTTPLKATSGPAIA-STATTLPT 700
TP P PP P +PP + A T GP T + SGP + + A P
Sbjct: 518 TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT---SVSGPRLTLALAPGPPP 574
Query: 701 TTSQLMAEKDSGP--AGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKT 758
S+ + SGP AG +S STP + RG S E +AA PP
Sbjct: 575 PPSRSPSSTLSGPDLAGH----SSSATSTPEELRGYDSGPEG---------GAAASPP-- 619
Query: 759 SPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASA 817
P CH ++ SR A P LA GA PG P+ P PA P SA
Sbjct: 620 -------PDAELAACHPAAWSRGPA---PPLAFRGA--PGAPL-----PWPPATGPGSA 661
Score = 72.4 bits (176), Expect = 2e-12
Identities = 206/875 (23%), Positives = 279/875 (31%), Gaps = 187/875 (21%)
Query: 356 RAPEPDCPGELKATAPASPR------------LGQS----QSQADERAGTPPPAPPLPPP 399
R P PG L P SPR LG + + ERAG A +P
Sbjct: 15 RTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGAT-IPES 73
Query: 400 APPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPV 459
AP P PPA+ A A + G +P +S +P P ++ V
Sbjct: 74 APRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV 133
Query: 460 DWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLP 519
++ K R+ L+A G+RR+ GPT S + R E L P
Sbjct: 134 ARGKATEAPK-RSALSA---GARRDTS------GPTPGTPSPAMARRSRAAGTEVGLPRP 183
Query: 520 AKDTPPGVP----EKSLGGSSL-TETEAAPSLTL-PSVDYIPQDSPTPSVRQIRNELEAR 573
A P P KS+ +S + TE +P+ PS Q + S+ L +
Sbjct: 184 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 243
Query: 574 LSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQP 633
S P + P +P+ +G + PPQ T P P
Sbjct: 244 ARSGPSARGTPRAPAHPSQPKPKGLQALR----------------PPQVTP--PRKDAAP 285
Query: 634 KAMLGP-AIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATS----- 687
LGP + P ATP P+ PP P+ PP P+ P S TT L + +
Sbjct: 286 A--LGPLSSSPLATPSPSAPPS----PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH 339
Query: 688 ----GPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRL 743
P ++ AT P L P P P ++TPS P L
Sbjct: 340 SFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS-------PQAPNAL 392
Query: 744 PTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEV 803
++ + PP P + P +S + P+ A A P P++V
Sbjct: 393 AVHLLQAPFSPPPS--------PPVQAPFSPPASPPVSPSATPPSQAPPSLAAP--PLQV 442
Query: 804 KEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSS 863
PP PA PP S T +P L Q A+ AL
Sbjct: 443 --PPSPPASPPMSPSATPP------------PQAPPPLAAPPLQLAKPPPQAPPALATPP 488
Query: 864 LPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRD 923
L QA S + F Q P P + SPL T
Sbjct: 489 L---------QALPSPPASFPGQA--------PFSPSASLPMSPLAT------------- 518
Query: 924 AEGTELSRRHNWTKPEPQAPVAWE----RVAPSNLPQGHPLPKSFSSPPSPSNKREEEEE 979
P PQAP +V PS P P ++ PP+P
Sbjct: 519 --------------PPPQAPPVLAAPLLQVPPS--PPASPTLQAPRRPPTPGPDTSVSGP 562
Query: 980 EFNFEVIP-PPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLRQL---PNAGPGAPPA-- 1033
+ P PPP S P G SS + +LR P G A P
Sbjct: 563 RLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT-STPEELRGYDSGPEGGAAASPPPD 621
Query: 1034 --------LGFSRFPAGA-RYAGAGGLER----FSGGGRSLIKKRLYVGE------PHRG 1074
+SR PA + GA G +G G + +Y E P G
Sbjct: 622 AELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG 681
Query: 1075 ---PGLPHGGTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPGGLHAP-------RLSLEG 1124
PG G +G ++ G P+ R+ G P G L A R L
Sbjct: 682 ALDPGPSPGTSGGKAAAGAGAGASSRSPKQARL---GELPLGALQASVVQHLLSRTLLLA 738
Query: 1125 AARGAAEAKHKAPGSADYGFAPAAGRSPYTTTRYG 1159
AA GAA PG A+ G R+ + G
Sbjct: 739 AAEGAAGGSGGGPGGAEGGGVTGGARAALSDAELG 773
Score = 71.6 bits (174), Expect = 4e-12
Identities = 123/522 (23%), Positives = 169/522 (32%), Gaps = 97/522 (18%)
Query: 376 LGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPK 435
+ + +A A PA P P PP +P PP P P A + + P
Sbjct: 1 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPP--PVTPAALRVLGAAGAVGRKPL 58
Query: 436 SS-----SPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSH 490
+ A P+ P + S P R + +N + R +
Sbjct: 59 AERAGGIGGATIPESAPRAGPTRTSRPPASGRG-ERAPPAKNTSPGPVSSPGRASG--TT 115
Query: 491 RPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTP-----------------PGVPEKSLG 533
RPGP G+KG R+ +ET+ A + P PG P ++
Sbjct: 116 RPGPL-------GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMA 168
Query: 534 -GSSLTETEAAPSLTLPSV-DYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPP 591
S TE PS P + P SV S AA + +PS G
Sbjct: 169 RRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR--RPSAGGGLQ 226
Query: 592 KPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPK----------------- 634
+P R + A LS P + T P QPK
Sbjct: 227 RP---ASRSLSSSA--TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK 281
Query: 635 ---AMLGP-AIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATS--- 687
LGP + P ATP P+ PP P+ PP P+ P S TT L + +
Sbjct: 282 DAAPALGPLSSSPLATPSPSAPPS----PSAPPSLQTLPSPPATPPSQATTSLGSPTLQA 337
Query: 688 ------GPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPS------------ 729
P ++ AT P L P P P ++TPS
Sbjct: 338 THSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLL 397
Query: 730 QARGEGSPSEATRL----PTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVV 785
QA PS + P S +A PP +P P L P +S +
Sbjct: 398 QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 457
Query: 786 MPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHP 827
P A A P P+++ +PP P PPA A P + L P
Sbjct: 458 PPPQAPPPLAAP--PLQLAKPP--PQAPPALATPPLQALPSP 495
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 103 bits (256), Expect = 1e-21
Identities = 127/453 (28%), Positives = 172/453 (37%), Gaps = 62/453 (13%)
Query: 208 IPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASP----HTVGTRLFPPGGVTKWKSDVA 263
+P PP PP PPL PPPPP+ AP PP P++P T R P G + +D+
Sbjct: 1 MPVPP---PPPPPLP---PPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQ 54
Query: 264 LNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPT--PVRTSSIPVQEAQ 321
R + T+ + +P S+ G N E + PPT + PV
Sbjct: 55 QGTRLRKVTQINDRSAPQIE--SSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPA 112
Query: 322 EAPRKEEGATKKAP-SRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQ 380
G T + P SR P P R P G L PASPRLG +
Sbjct: 113 GQRDVAGGKTGQGPGSRAPSP--------------RLPNKTISGPL--IPPASPRLGNT- 155
Query: 381 SQADERAGTPPPAPPLPPPAPPLPPPAPP-LPPAAP-PLPCAQKAAHPPAGFTK-TPKSS 437
S+A A T PP P +P P PP PPP PP LPP P P PP TK
Sbjct: 156 SEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVV 215
Query: 438 SPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVA 497
+P + P PP P + P+ + ++ +LA P P +
Sbjct: 216 APPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAPLHLPP-------IPPPLPLLP 268
Query: 498 PQSKEGKKG-PRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQ 556
P G K P P ++ PP P +S + + P+ LP V+ +
Sbjct: 269 PCGYPGLKAEPASPAQDA-------QEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSE 321
Query: 557 DSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPP--KPRLEGGRICENGADDDKLSKPV 614
P + + + + A A P+ PP +P L+ R GA KL+ P
Sbjct: 322 TPPPLPPKSPSFQAPPQKAGAQALPAPPA----PPGSQPFLQKKRHGRPGAGGGKLNPPP 377
Query: 615 AKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATP 647
A PP + PTT L K+ A P P
Sbjct: 378 A---PPARS---PTTELSSKSQQATAWTPTQQP 404
Score = 94.0 bits (232), Expect = 8e-19
Identities = 102/326 (31%), Positives = 117/326 (35%), Gaps = 92/326 (28%)
Query: 142 PPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPH 201
PP P G + +P P P APPPP PPPPP PPP P + P
Sbjct: 146 PPASPRLGNTSEAHGAARTAP-PRPNVPAPPPPT----PPPPPPPLPPPLPSSSPIKTP- 199
Query: 202 TLSSPSIPTPPDFIPP-APPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKS 260
L SP P +P APP+ PPPPP P P PP PP V S
Sbjct: 200 -LVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPP-----------LPPASVL---S 244
Query: 261 DVALNGRQAEATRAS-PPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQE 319
D A+ + A PP P P G EP + P Q+
Sbjct: 245 DKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEP-------------------ASPAQD 285
Query: 320 AQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQS 379
AQE P AP PLPP P +A+ PA P G +
Sbjct: 286 AQEPP---------APPP-PLPPYASCSP------------------RASLPAPPLPGVN 317
Query: 380 QSQADERAGTPPPAPPLPPP--APPLPP-----PAPPLPPAAPPLPCAQKAAHPPAGFTK 432
S TPPP PP P APP PAPP PP + P ++ P AG K
Sbjct: 318 SSSE-----TPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGK 372
Query: 433 TPKSSSPALKPKPNPP--SPENTASS 456
L P P PP SP SS
Sbjct: 373 --------LNPPPAPPARSPTTELSS 390
Score = 89.4 bits (220), Expect = 2e-17
Identities = 88/292 (30%), Positives = 112/292 (38%), Gaps = 73/292 (25%)
Query: 138 LIPPPPP-----GPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPP 192
LIPP P A G + + P P P PP+ PPPPPL PPP PS +P P
Sbjct: 144 LIPPASPRLGNTSEAHGAART-APPRPNVPAPPPPTPPPPPPPL---PPPLPSSSPIKTP 199
Query: 193 VLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTV------- 245
++ SPP L+ ++P PP P APPPPP P P P P P +V
Sbjct: 200 LV---SPPGPLTKGNLPV---VAPPVP----CAPPPPPPPPPPTPPPLPPASVLSDKAVK 249
Query: 246 -------------GTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNP 292
L PP G K++ A + A+ A PP P S P
Sbjct: 250 PQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLP 309
Query: 293 EPHLT-FPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQ 351
P L S + PPP P ++ S +AP ++ GA LP PP+ P SQ
Sbjct: 310 APPLPGVNSSSETPPPLPPKSPSF------QAPPQKAGA-----QALPAPPA---PPGSQ 355
Query: 352 VYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPL 403
+ L+ P G + PPPAPP P L
Sbjct: 356 PF------------LQKKRHGRPGAGGGKL-------NPPPAPPARSPTTEL 388
Score = 77.4 bits (189), Expect = 7e-14
Identities = 79/294 (26%), Positives = 100/294 (34%), Gaps = 82/294 (27%)
Query: 141 PPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPP----------PPLLLEPPPPPSMAPPP 190
PPPP P P PP P SP+ +P + P P PP+ PPPPP PPP
Sbjct: 174 PPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPP---PPP 230
Query: 191 PPVLEALSPPHTLSSPSIPTP--PDFIPPAPPLAFLAPP-------------------PP 229
PP L P LS ++ P +PP PP L PP PP
Sbjct: 231 PPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPP 290
Query: 230 PVPAPAPP-APASPHTVGTRLFPPGGVTKWKSDVALNGR----QAEATRASPPRSPAEPK 284
P P PP A SP PG + ++ L + QA +A PA P
Sbjct: 291 APPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPA 350
Query: 285 GSALGPNPEPHLTFPRSFKV--------PPPTPVRTSSIPVQEAQEAPRKEEGATKKAPS 336
P +P L R + PPP P S E K + AT P+
Sbjct: 351 P----PGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSP-----TTELSSKSQQATAWTPT 401
Query: 337 RLP--------------------------LPPSFHIRPASQVYPDRAPEPDCPG 364
+ P PP +P ++YP + P PG
Sbjct: 402 QQPGGQLRNGSLHIIDDFESKFTFHSVEDFPPPDEYKPCQKIYPSKIPRSRTPG 455
Score = 54.7 bits (130), Expect = 5e-07
Identities = 121/508 (23%), Positives = 157/508 (30%), Gaps = 121/508 (23%)
Query: 394 PPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENT 453
P PPP PPLPPP PPL PP P A PP +T
Sbjct: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSA--------------------------PPVSTDT 35
Query: 454 ASSAPVDWRDPSQMEKLRNELAAYLCGSR-REDRFLSHRPGPTVAPQSKEGKKGPRLPEK 512
+S D + S + LA G+R R+ ++ R P + K+G
Sbjct: 36 SSLRRADPKGRSAL------LADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANT 89
Query: 513 ETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEA 572
TPP + + GG P +R A
Sbjct: 90 R------GASTPPTLGDLFAGGF-------------------------PVLRP------A 112
Query: 573 RLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQ 632
A + GS P PRL I S P+ +PP S L T+
Sbjct: 113 GQRDVAGGKTGQGPGSRAPSPRLPNKTI----------SGPL---IPPASPRLGNTSEAH 159
Query: 633 PKAMLGPA-----IPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTT----PL 683
A P PP TP P PP P++ P TPL + GP T P+
Sbjct: 160 GAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSP-----IKTPLVSPPGPLTKGNLPV 214
Query: 684 KATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQA--RGEGSPSEAT 741
A P P T P P S + P A P
Sbjct: 215 VAPPVPCAPPPPPPPPPPTP---------PPLPPASVLSDKAVKPQLAPLHLPPIPPPLP 265
Query: 742 RLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPV 801
LP G A P + E P P +S S ++ P L PG
Sbjct: 266 LLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPL-------PGVNS 318
Query: 802 EVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGR 861
+ PP LP K P+ P + + GS L Q+ + GR GA G+
Sbjct: 319 SSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFL-----QKKRHGRP-GAGGGK 372
Query: 862 SSLPGSLRDHSHQAEASSDSIFHSQGTP 889
+ P + S E SS S + TP
Sbjct: 373 LNPPPAPPARSPTTELSSKSQQATAWTP 400
Score = 43.1 bits (100), Expect = 0.002
Identities = 68/270 (25%), Positives = 90/270 (33%), Gaps = 39/270 (14%)
Query: 800 PVEVKEPPGLPAKPPA-SAQPTDELLRHPVTGEV--VERGSPM--ALLLAARQRAQKGRS 854
PV PP LP PP A P PV+ + + R P + LLA Q+ + R
Sbjct: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRK 61
Query: 855 VGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVV-----PKLPKEAEKD---- 905
V RS+ P E + TP + + P L ++D
Sbjct: 62 VTQINDRSA-PQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGG 120
Query: 906 ---------SPLTTEIPNKW---------GPRLGRDAEGTELSR----RHNWTKPEPQAP 943
+P + +PNK PRLG +E +R R N P P P
Sbjct: 121 KTGQGPGSRAP-SPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTP 179
Query: 944 VAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDP-EPPAPA 1002
P LP P+ SPP P K PPPP P PP P
Sbjct: 180 PPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPP 239
Query: 1003 LQYLGRQSSPPRNNYSDLRQLPNAGPGAPP 1032
L ++ P+ L +P P PP
Sbjct: 240 ASVLSDKAVKPQLAPLHLPPIPPPLPLLPP 269
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 101 bits (251), Expect = 5e-21
Identities = 112/420 (26%), Positives = 154/420 (36%), Gaps = 68/420 (16%)
Query: 158 PGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPP 217
P P P+ P P L+ PP + PP AL P LSS + TP P
Sbjct: 257 PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP---LSSSPLATPS----P 309
Query: 218 APPLAFLAPPPPPV-------------PAP-APPAPASPHTVGTRLFPPGGVTKWKSDVA 263
+ L APP P P P APP+P++P ++ T PP ++ +
Sbjct: 310 SAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPS-QATTS 368
Query: 264 LNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEA 323
L +AT + P P P + PP P + P+Q A
Sbjct: 369 LGSPTLQATHSFLPSPPLSPLATP-----------------PPQAPPALALPPLQ----A 407
Query: 324 PRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQ--- 380
P + +P P P + + + +P P P + + PASP + S
Sbjct: 408 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 467
Query: 381 SQADERAGTPP-PAPPLPPPAPPLPPPAPPLPPAAPPL--PCAQKAAHPPAGFTKTPKSS 437
SQA PP PP PP +PP+ P A P P A PPL P Q A PP P +
Sbjct: 468 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA---PPALA 524
Query: 438 SPALKPKPNPP---------SPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFL 488
+P L+ P+PP SP + +P+ P L L
Sbjct: 525 TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ 584
Query: 489 SHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPG-VPEKSLGGSSLTETEAAPSLT 547
+ R PT P + GPRL TL P PP P +L G L ++ + T
Sbjct: 585 APRRPPTPGPDT--SVSGPRL----TLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATST 638
Score = 95.1 bits (235), Expect = 3e-19
Identities = 131/498 (26%), Positives = 170/498 (34%), Gaps = 60/498 (12%)
Query: 141 PPPPGPAPGPPQDISEP-----PGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLE 195
P P G P ++ P P PL S P P P L PP A P L
Sbjct: 272 PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLT 331
Query: 196 A-LSPPHTLSSPS---------IPTPPDFIP-------------------PAPPLAFLAP 226
L+ P L+ PS +P+PP P P+PPL+ LA
Sbjct: 332 CQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT 391
Query: 227 PPPPVPAPA---PPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAE- 282
PPP P PA PP A P + P ++ AL +A + PP P +
Sbjct: 392 PPPQAP-PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 450
Query: 283 ----PKGSALGPNPEPHLTFPRSFKVPP--PTPVRTSSIPVQEAQEAPRKEEGATKKAPS 336
P + P+ P P S PP P +S P+ + P + P
Sbjct: 451 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 510
Query: 337 RLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPL 396
+L PP P + P P P AP SP S S TPPP P
Sbjct: 511 QLAKPPP--QAPPALATPPLQALPSPPASFPGQAPFSP----SASLPMSPLATPPPQAPP 564
Query: 397 PPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPP---SPENT 453
AP L PP PPA+P L ++ P + + + AL P P PP SP +T
Sbjct: 565 VLAAPLL--QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 622
Query: 454 ASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLP-EK 512
S + S EL Y G A +GP P
Sbjct: 623 LSGPDLAGHS-SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAF 681
Query: 513 ETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEA 572
P P P + G ++ ETE S T P SP S + A
Sbjct: 682 RGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGA 741
Query: 573 RLSSAAEKEAKPSIGSLP 590
SS + K+A+ +G LP
Sbjct: 742 GASSRSPKQAR--LGELP 757
Score = 94.4 bits (233), Expect = 6e-19
Identities = 196/750 (26%), Positives = 257/750 (34%), Gaps = 144/750 (19%)
Query: 146 PAPGPPQDISEPPGGSPLPSPPST-----------APPPPPLL-----LEPPPPPSMAPP 189
PA P ++ P GSP P PP T A PL + P AP
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 190 PPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRL 249
P T S+ + P PPA APP +P P + + TR
Sbjct: 77 AGP---------TRSAGTSSRNPASRPPASGRGERAPPAKNT-SPGPVSSPGRASGTTRP 126
Query: 250 FPPG--GVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNP-EPHLTFPRSFK--- 303
P G G+ + G+ EA + S + A S GP P P R +
Sbjct: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTS--GPTPGTPSPAMARRSRAAG 184
Query: 304 ----VPPPTPVRTSSIPVQEAQEAPRK------EEGATKKAPS--RLPLPPSFHIRPASQ 351
+P P P P E PRK E T+ +P+ R P RPAS+
Sbjct: 185 TEVGLPRPAPSARPRPPT----EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240
Query: 352 VYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPL- 410
A P +A +PR SQ + P + PP P PL
Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300
Query: 411 -PPAAPPLPCAQKAAHPPAGFTKTPKSSS---------PALKPKPNPPSPENTASSAPVD 460
P A P P A + P TP SSS P P P+ P T S P
Sbjct: 301 SSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPA- 359
Query: 461 WRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPA 520
PSQ A GS S P P ++P + P+ P L L A
Sbjct: 360 -TPPSQ--------ATTSLGSPTLQATHSFLPSPPLSPLA---TPPPQAPPALALPPLQA 407
Query: 521 KDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAA-- 578
+PP P S + + A ++ L + P SP P +S +A
Sbjct: 408 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP-PVQAPFSPPASPPVSPSATP 466
Query: 579 EKEAKPSIGS----LPPKPRLEGGRICENGADDDKLSKPVA------KNLPPQSTTLLPT 628
+A PS+ + +PP P + + + P+A PPQ+ L T
Sbjct: 467 PSQAPPSLAAPPLQVPPSPP-ASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT 525
Query: 629 TSLQ-----PKAMLGPA---------IPPKATPEPAIPPKATL----WPATPPKATLGPA 670
LQ P + G A + P ATP P PP P +PP + A
Sbjct: 526 PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 585
Query: 671 TPLKATSGPTTPLKATSGPAIA-STATTLPTTTSQLMAEKDSGP--AGQPEKPASQEVST 727
T GP T + SGP + + A P S+ + SGP AG +S ST
Sbjct: 586 PRRPPTPGPDT---SVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGH----SSSATST 638
Query: 728 PSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMP 787
P + RG S E +AA PP P CH ++ SR A P
Sbjct: 639 PEELRGYDSGPEG---------GAAASPP---------PDAELAACHPAAWSRGPA---P 677
Query: 788 TLARGGAAGPGEPVEVKEPPGLPAKPPASA 817
LA GA PG P+ P PA P SA
Sbjct: 678 PLAFRGA--PGAPL-----PWPPATGPGSA 700
Score = 94.0 bits (232), Expect = 8e-19
Identities = 192/785 (24%), Positives = 265/785 (33%), Gaps = 171/785 (21%)
Query: 126 GDLRPGQYGQDLLI--------------PPPPPGPAPGPPQDISEPPGGSPLPSPPSTAP 171
G RPG GQ L P + G +D S P G+P P+ +
Sbjct: 122 GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR 181
Query: 172 PPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPV 231
+ P P PS P PP P ++SS S + +
Sbjct: 182 AAGTEVGLPRPAPSARPRPPTE----GPRKSVSSASEHSTTE------------------ 219
Query: 232 PAPAPPAPASPHTVGTRLFPPG-GVTKWKSDVALNGRQAEATRASP--PRSPAEPKGSAL 288
P+P A P G P ++ + ++ R + R +P P P++PK L
Sbjct: 220 --PSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGL 277
Query: 289 GPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPP---SFH 345
P +T PR P P+ +S + P +AP LP P S
Sbjct: 278 QALRPPQVTPPRKDAAPALGPLSSSPLAT------PSPSAALQSQAPPTLPATPHSSSLT 331
Query: 346 IRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPP--------PAPPLP 397
+ A+ + P P P P L+ T P+ P SQA G+P P+PPL
Sbjct: 332 CQLATPL-PLAPPSPSAPPSLQ-TLPSPP--ATPPSQATTSLGSPTLQATHSFLPSPPLS 387
Query: 398 PPA--PPLPPPAPPLPPA-APPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTA 454
P A PP PPA LPP APP P A PP SP P P P
Sbjct: 388 PLATPPPQAPPALALPPLQAPPSP----PASPPL---------SPLATPSPQAP------ 428
Query: 455 SSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKET 514
N LA +L + S P P V + P P
Sbjct: 429 -----------------NALAVHLLQAP-----FSPPPSPPV--------QAPFSPPASP 458
Query: 515 LLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARL 574
+S A TPP SL L + P+ S P P + +L
Sbjct: 459 PVSPSA--TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP 516
Query: 575 SSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPK 634
A A P + +LP P G+ A P S + P + P+
Sbjct: 517 PQAPPALATPPLQALPSPPASFPGQ---------------APFSPSASLPMSPLATPPPQ 561
Query: 635 AMLGPAIPPKATPEPAIPPKATLWPAT----------PPKATLGPATPLKATSGP----- 679
A P A P +PP P P + GP L GP
Sbjct: 562 AP-----PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 616
Query: 680 TTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAG--QPEKPASQEVSTPSQARGEGSP 737
+P SGP +A +++ +T +L DSGP G P E++ A P
Sbjct: 617 RSPSSTLSGPDLAGHSSSATSTPEELRG-YDSGPEGGAAASPPPDAELAACHPAAWSRGP 675
Query: 738 SEATRLPTQGARSS-AAFPPKTSPGGGEVPC-LYKPHCHQSSLSREVAV---VMPTLARG 792
A L +GA + +PP T PG + C +Y+ +S+ A+ P + G
Sbjct: 676 --APPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGG 733
Query: 793 -GAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQK 851
AAG G G ++ P A+ EL + VV+ LLLAA + A
Sbjct: 734 KAAAGAG--------AGASSRSPKQAR-LGELPLGALQASVVQHLLSRTLLLAAAEGAAG 784
Query: 852 GRSVG 856
G G
Sbjct: 785 GSGGG 789
Score = 93.6 bits (231), Expect = 1e-18
Identities = 120/427 (28%), Positives = 149/427 (34%), Gaps = 68/427 (15%)
Query: 92 LAVPTPSVPDDFADKEVTGTSSLVNGNLRLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPP 151
LA P+PS P T S + +S+G P +P PP P PP
Sbjct: 340 LAPPSPSAPPSLQ----TLPSPPATPPSQATTSLGS--PTLQATHSFLPSPPLSPLATPP 393
Query: 152 QDISEPPGGSPLPSPPSTAPPPPPLLLEPPPP-------------PSMAPPPPPVLEALS 198
PL +PPS PP L P P P PP PPV S
Sbjct: 394 PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 453
Query: 199 PPHTLSSPSIPTPPDFIPP---APPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGV 255
PP + TPP PP APPL PP PP P P+ P L P
Sbjct: 454 PPASPPVSPSATPPSQAPPSLAAPPLQ--VPPSPPASPPMSPSATPPPQAPPPLAAP--- 508
Query: 256 TKWKSDVALNGRQAEATRASPP-RSPAEPKGSALGPNP-EPHLTFPRS-FKVPPPTPVRT 312
+A QA A+PP ++ P S G P P + P S PPP
Sbjct: 509 ---PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV 565
Query: 313 SSIPVQEAQEAPRKEEGATKKAPSRLPLPP----------SFHIRPASQVYPDRAPE--- 359
+ P+ Q P T +AP R P P + + P P R+P
Sbjct: 566 LAAPL--LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL 623
Query: 360 --PDCPG-ELKATAPASPRLGQSQSQADERAGTPPPAPPLPP--PAPPLPPPAPPLP-PA 413
PD G AT+ G A +PPP L PA PAPPL
Sbjct: 624 SGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRG 683
Query: 414 APPLPCAQKAAHPPAGF--------TKTPKSSSP---ALKPKPNPPSPENTASS---APV 459
AP P A P T+ P+S++P AL P P+P + A++ A
Sbjct: 684 APGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGA 743
Query: 460 DWRDPSQ 466
R P Q
Sbjct: 744 SSRSPKQ 750
Score = 74.3 bits (181), Expect = 6e-13
Identities = 210/883 (23%), Positives = 281/883 (31%), Gaps = 170/883 (19%)
Query: 376 LGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPL--------------PCAQ 421
+ + +A A PA P P PP +P PP P P A+
Sbjct: 1 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60
Query: 422 KAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGS 481
+A G P+S+ A + S N AS P R + +N +
Sbjct: 61 RAG--GIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRG-ERAPPAKNTSPGPVSSP 117
Query: 482 RREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTP----------------- 524
R + RPGP G+KG R+ +ET+ A + P
Sbjct: 118 GRASG--TTRPGPL-------GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT 168
Query: 525 PGVPEKSLG-GSSLTETEAAPSLTLPSV-DYIPQDSPTPSVRQIRNELEARLSSAAEKEA 582
PG P ++ S TE PS P + P SV S AA +
Sbjct: 169 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR-- 226
Query: 583 KPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPK-----AML 637
+PS G +P R + A LS P + T P QPK A+
Sbjct: 227 RPSAGGGLQRP---ASRSLSSSA--TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR 281
Query: 638 GPAI-PPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTAT 696
P + PP+ PA+ P ++ P AT P+ L++ + PT P S AT
Sbjct: 282 PPQVTPPRKDAAPALGPL-----SSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLAT 336
Query: 697 TLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGE-GSPS-EATR--LPTQGARSSA 752
LP L S P P S + PSQA GSP+ +AT LP+ A
Sbjct: 337 PLP-----LAPPSPSAPPSLQTLP-SPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA 390
Query: 753 AFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAA---------GPGEPVEV 803
PP+ P P P S +A P A P PV+
Sbjct: 391 TPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 450
Query: 804 K-EPPGLP-----AKPPASAQPT--DELLRHPVTGEVVERGSPMALLLAARQRAQKGRSV 855
PP P A PP+ A P+ L+ P + SP A +
Sbjct: 451 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 510
Query: 856 GAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNK 915
A P +L QA S + F Q P P + SPL T
Sbjct: 511 QLAKPPPQAPPALATPPLQALPSPPASFPGQ--------APFSPSASLPMSPLAT----- 557
Query: 916 WGPRLGRDAEGTELSRRHNWTKPEPQAPVAWE----RVAPSNLPQGHPLPKSFSSPPSPS 971
P PQAP +V PS P P ++ PP+P
Sbjct: 558 ----------------------PPPQAPPVLAAPLLQVPPS--PPASPTLQAPRRPPTPG 593
Query: 972 NKREEEEEEFNFEVIP-PPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLRQL---PNAG 1027
+ P PPP S P G SS + +LR P G
Sbjct: 594 PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS-ATSTPEELRGYDSGPEGG 652
Query: 1028 PGAPP----------ALGFSRFPA-GARYAGAGGL----ERFSGGGRSLIKKRLYVGE-- 1070
A P +SR PA + GA G +G G + +Y E
Sbjct: 653 AAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGP 712
Query: 1071 ----PHRG---PGLPHGGTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPGGLHA------ 1117
P G PG G +G ++ G P+ R+ G P G L A
Sbjct: 713 ESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARL---GELPLGALQASVVQHL 769
Query: 1118 -PRLSLEGAARGAAEAKHKAPGSADYGFAPAAGRSPYTTTRYG 1159
R L AA GAA PG A+ G R+ + G
Sbjct: 770 LSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAALSDAELG 812
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 101 bits (251), Expect = 5e-21
Identities = 149/589 (25%), Positives = 197/589 (33%), Gaps = 106/589 (17%)
Query: 149 GPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSI 208
G P + +P P AP PPP P P PP SP
Sbjct: 65 GSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPP------------SPRR 112
Query: 209 PTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQ 268
P P PAPP A L PPP P PA+ P G K AL
Sbjct: 113 PLVP--AGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAAL---- 166
Query: 269 AEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEE 328
A RA P P GP P P P P S + + A
Sbjct: 167 --AARAGPGPGPGP------GPGPGPGPGKPAG---PGAAQTLNGSAALLNSHHAAAPAV 215
Query: 329 GATKKAPSR-LPLP----PSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQA 383
P+ LPLP P I+ V P P P A APA+P
Sbjct: 216 SLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAP--------- 266
Query: 384 DERAGTPPPAPPLP-----PPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSS 438
A PPP PP P PP P PP PA PP AQ A P +
Sbjct: 267 ---AAAPPPPPPAPATLARPPGHPAGPPT--AAPAVPPPAAAQNGGSAGAAPAPAPAAGG 321
Query: 439 PALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAP 498
PA P A + V P ++ + A L S S GPT+
Sbjct: 322 PAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQ- 380
Query: 499 QSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGG--SSLTETEAA----------PSL 546
LP + PA TP G+P+ + G SL+ T A P++
Sbjct: 381 --------GALP-SPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTV 431
Query: 547 TLPSVDYIPQDSPT--------PSVRQIRNE--------LEARLSSAAEKEAKPSIGSLP 590
P + PQ +PT P + +R+E +A A+ A+P ++
Sbjct: 432 LAPRLPQPPQ-NPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQT-TMA 489
Query: 591 PKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPE-- 648
P+P A ++S A P + + PTT ++ + + P AT +
Sbjct: 490 PRP------ATPTSAPPVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRS 543
Query: 649 PAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTATT 697
P + P+ L A A+LG AT ++ TP + G S+A T
Sbjct: 544 PGVQPQLVLGGAA-QTASLGTATAVQT----GTPQRTVPGATTTSSAAT 587
Score = 76.3 bits (186), Expect = 2e-13
Identities = 173/723 (23%), Positives = 249/723 (34%), Gaps = 134/723 (18%)
Query: 140 PPPPPGPAPGPPQDISEPPGGSP--------LPSPPSTAP--------PPPPLLLEPPPP 183
P P PGP PGP PG + L S + AP P L L P
Sbjct: 174 PGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAA 233
Query: 184 PSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPA----- 238
P PP + A +PP +P+ P+PP PA P A APPPPP PAP
Sbjct: 234 PGTVIQTPPFVGAAAPP----APAAPSPPAAPAPAAPAA--APPPPP---PAPATLARPP 284
Query: 239 --PASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHL 296
PA P T + PP A NG A A A PA G G + +P
Sbjct: 285 GHPAGPPTAAPAVPPPA--------AAQNGGSAGAAPA-----PAPAAGGPAGVSGQPG- 330
Query: 297 TFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDR 356
P + P V+ S P + Q AP PA+Q
Sbjct: 331 --PGAAAAAPAPGVKAES-PKRVVQAAP-----------------------PAAQTLAAS 364
Query: 357 APEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPP 416
P A+ AS +G + G P +PPPAP P P A
Sbjct: 365 GP---------ASTAASMVIGPTMQ------GALPSPAAVPPPAPGTPTGLPKGAAGAVT 409
Query: 417 LPCAQKAAHPPAGF--TKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNEL 474
++ +G T TP +P L P+P P +P N +++ P M +R+E
Sbjct: 410 QSLSRTPTATTSGIRATLTPTVLAPRL-PQP-PQNPTNIQ-----NFQLPPGMVLVRSEN 462
Query: 475 AAYLCGSRR---EDRFLSH-RPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTP----PG 526
L ++ + + +H +P T+AP+ P + + ++ A TP
Sbjct: 463 GQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPV----QISTVQAPGTPIIARQV 518
Query: 527 VPEKSLGGSSLTETEAAPSLTLP-SVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKP- 584
P + S +T PS TL S PQ + + + + + P
Sbjct: 519 TPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQRTVPG 578
Query: 585 -SIGSLPPKPRLEGGRICENG-------ADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAM 636
+ S +E + C+N A K S A N+ LL
Sbjct: 579 ATTTSSAATETMENVKKCKNFLSTLIKLASSGKQSTETAANVKELVQNLLDGKIEAEDFT 638
Query: 637 LGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTAT 696
++P+P + P L + P L P + P TS A TA
Sbjct: 639 SRLYRELNSSPQPYLVP--FLKRSLPALRQLTPDSAAFIQQSQQQPPPPTSQATTALTAV 696
Query: 697 TLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAF-- 754
L +++ Q A K + +P ++ P+Q G G + T L Q A
Sbjct: 697 VL-SSSVQRTAGKTAATVTSALQPPVLSLTQPTQV-GVGKQGQPTPLVIQQPPKPGALIR 754
Query: 755 PPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPP 814
PP+ + + L +PH +M T + P +PV V +P LP
Sbjct: 755 PPQVTLTQTPMVALRQPHNR----------IMLTTPQQIQLNPLQPVPVVKPAVLPGTKA 804
Query: 815 ASA 817
SA
Sbjct: 805 LSA 807
Score = 72.8 bits (177), Expect = 2e-12
Identities = 99/356 (27%), Positives = 126/356 (35%), Gaps = 67/356 (18%)
Query: 110 GTSSLVNGNLRLYSSVGDLRPG----QYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPS 165
G + +NG+ L +S P G L+P P P APG + + P +
Sbjct: 193 GAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPA-APGT---VIQTPPFVGAAA 248
Query: 166 PPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLA 225
PP+ A P PP P P + PPPPP P TL+ PP P PP A A
Sbjct: 249 PPAPAAPSPPAAPAPAAPAAAPPPPPPA------PATLA-----RPPGH-PAGPPTAAPA 296
Query: 226 PPPP------------PVPAPAPPAPA----SPHTVGTRLFPPGGV--TKWKSDVALNGR 267
PPP P PAPA PA P P GV K V
Sbjct: 297 VPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPP 356
Query: 268 QAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKE 327
A+ AS P S A +GP + L P + VPPP P + +P A
Sbjct: 357 AAQTLAASGPASTA--ASMVIGPTMQGALPSPAA--VPPPAPGTPTGLPKGAA------- 405
Query: 328 EGATKKAPSRLPLPPSFHIRP--ASQVYPDRAPEPD-----------CPGELKATAPASP 374
GA ++ SR P + IR V R P+P PG + +
Sbjct: 406 -GAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQ 464
Query: 375 RL---GQSQSQADERAGTPPPAPPLPPPAPPL-PPPAPPLPPAAPPLPCAQKAAHP 426
L Q+ +Q +A P P PA P PP AP P + P
Sbjct: 465 LLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQVTP 520
Score = 42.7 bits (99), Expect = 0.002
Identities = 49/201 (24%), Positives = 68/201 (33%), Gaps = 33/201 (16%)
Query: 638 GPAIPPKA-TPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTAT 696
GP P + P PP A L P PP+ + G P+ A + +GP A
Sbjct: 106 GPPSPRRPLVPAGPAPPAAKLRP--PPEGSAGSCAPVPAAAA------VAAGPEPAPAGP 157
Query: 697 TLPTTTSQLMAEKDSGPA-----------GQPEKPASQEVSTPSQA--RGEGSPSEATRL 743
P + L A GP G+P P + + S A + + A L
Sbjct: 158 AKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSL 217
Query: 744 PTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARGGAAG------- 796
G + P +PG + P ++ A P A AA
Sbjct: 218 VNNGPAALLPLPKPAAPG----TVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPP 273
Query: 797 PGEPVEVKEPPGLPAKPPASA 817
P P + PPG PA PP +A
Sbjct: 274 PPAPATLARPPGHPAGPPTAA 294
Score = 41.6 bits (96), Expect = 0.005
Identities = 83/350 (23%), Positives = 107/350 (30%), Gaps = 50/350 (14%)
Query: 638 GPAIP----PKATPEPAIPPKATLWPATPPKATLGPATPLK--ATSGPTTPLKATSGPAI 691
GPA P P A PEP PP P GP +P + +GP P P
Sbjct: 74 GPAAPAEGAPGAAPEP--PPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPE 131
Query: 692 ASTATTLPTTTSQLMAE-KDSGPAGQPEKPASQEVST------------PSQARGEGSPS 738
S + P + +A + PAG P KPA P G G P+
Sbjct: 132 GSAGSCAPVPAAAAVAAGPEPAPAG-PAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPA 190
Query: 739 EATRLPTQGARSS------AAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARG 792
T ++ AA P + G L P V+ T
Sbjct: 191 GPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPK------PAAPGTVIQTPPFV 244
Query: 793 GAAGPGEPVEVKEP----PGLPAKPPASAQPTDELLRHPVTGEVVERGSPMAL-LLAARQ 847
GAA P P P P PA P P L P G P A +
Sbjct: 245 GAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPA---GPPTAAPAVPPPA 301
Query: 848 RAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSP 907
AQ G S GAA + G S Q + + + G V + PK + +P
Sbjct: 302 AAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPG------VKAESPKRVVQAAP 355
Query: 908 LTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQG 957
+ GP A + P P A P+ LP+G
Sbjct: 356 PAAQTLAASGP--ASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKG 403
Score = 35.8 bits (81), Expect = 0.25
Identities = 56/229 (24%), Positives = 77/229 (33%), Gaps = 47/229 (20%)
Query: 938 PEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPE 997
P+P AP + P P P + S P +P+ P P + P
Sbjct: 229 PKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPA---------------PAAPAAAPPPP 273
Query: 998 PPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPALGFSRFPAGARYAGAGGLERF--- 1054
PPAPA L R P P A P PP PA A+ G+ G
Sbjct: 274 PPAPAT--LARPPGHPAGP-------PTAAPAVPP-------PAAAQNGGSAGAAPAPAP 317
Query: 1055 SGGGRSLIKKRLYVGEPHRGPGLPHGGTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPGG 1114
+ GG + + G+P G G SP Q P + + ++G A
Sbjct: 318 AAGGPAGVS-----GQPGPGAAAAAPAPGVKAESPKRV-VQAAPPAAQTLAASGPASTAA 371
Query: 1115 LHAPRLSLEGAARGAAEAKHKAPGSADYGFAPAAG-------RSPYTTT 1156
+++GA A APG+ AAG R+P TT
Sbjct: 372 SMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATT 420
Score = 31.6 bits (70), Expect = 4.7
Identities = 55/237 (23%), Positives = 66/237 (27%), Gaps = 25/237 (10%)
Query: 950 APSNLPQGHPLPKSFS----SPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQY 1005
AP P G P PPSP + PPPE S P PA
Sbjct: 86 APEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAA 145
Query: 1006 LGRQSSP----PRNNYSDLRQLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRSL 1061
+ P P AGPG P G P + AG G + +G L
Sbjct: 146 VAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALL 205
Query: 1062 IKKRL---YVGEPHRGPG----LPH-GGTGRSLSSPNCFG---------PQPGGPEMRRV 1104
V + GP LP G + +P G P P
Sbjct: 206 NSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAA 265
Query: 1105 NSAGRAPPGGLHAPRLSLEGAARGAAEAKHKAPGSADYGFAPAAGRSPYTTTRYGSP 1161
+A PP A G G A P A +AG +P G P
Sbjct: 266 PAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGP 322
>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
Length = 1003
Score = 100 bits (250), Expect = 6e-21
Identities = 238/967 (24%), Positives = 314/967 (32%), Gaps = 185/967 (19%)
Query: 139 IPPPPPGPAPG----PPQDISEPPGGSPLPSPPS------TAPPP----PPLLLEPPP-- 182
+ P PP P P ++ PG P P PPS T P PP L +P P
Sbjct: 138 VSPGPPSARPPCRVPPTTPLNGGPGSLP-PEPPSVSQAFPTLAGPGGLFPPRLADPVPSG 196
Query: 183 ------------PPSMAPPPPPVLEALSPPHTLSSP--SIPTPPDF-IPPAPPLAFLAPP 227
PS APPPPP + +P + + S P D PPAP + P
Sbjct: 197 GSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPS 256
Query: 228 PPPV--------PAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRS 279
PP+ P P PP+ P G PP + L T P
Sbjct: 257 DPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAP 316
Query: 280 P--AEPKGSALGPNPEPHLTFPRSFKVPPP---TPVRTSSIPVQEAQEAPRKEEGATKKA 334
P A SA P L P + + P P + S ++ +Q PR+ +
Sbjct: 317 PFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLL 376
Query: 335 PSRLPLPP--SFHIRPASQVYPDRAPEPDCP------GELKATAPASPRLGQSQSQADER 386
R P P S PA P PEP P L P S +
Sbjct: 377 EGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSD 436
Query: 387 AGTPPPAPPLPPPAPPLP--PPAPPLP----------PAAPPLPCAQKAAHPPAGFTKTP 434
A PPP P L +PP P P P LP P AP P A KA P+ ++P
Sbjct: 437 AHLPPP-PTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSP 495
Query: 435 KSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGP 494
S + P P P A + P Q L + G+ L P
Sbjct: 496 -SEGLGMGAGPACPLPP-LAGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPS 553
Query: 495 TVAPQSKEG--KKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVD 552
+ S G G P E LL P PP P + G S L + P P D
Sbjct: 554 PLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLLPP----PPSD 609
Query: 553 YIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSK 612
+P S PS N L + L P + P EG G + S
Sbjct: 610 LLPPPSAPPS-----NLLASFL---------PLLALGPTAGDGEGSAEGAGGPSGEPFS- 654
Query: 613 PVAKNLPPQSTTLLPTTSLQPK--AMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPA 670
L S L P S P A+ + P PP+ + A P GP
Sbjct: 655 ----GLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQP----GPP 706
Query: 671 TPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQ 730
T + +TATT P +S A +SG Q P
Sbjct: 707 T------------------SSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDL 748
Query: 731 ARGEGSPSE-ATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTL 789
+ SP + L G S + PGGG P L S S +A ++ +L
Sbjct: 749 SSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPL-------SEASSPLACLLQSL 801
Query: 790 ARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGS---PMALLLAAR 846
P E E P LP + PASA E R P++ GS P+ LL R
Sbjct: 802 Q--------IPPEQPEAPCLPPESPASAL-EPEPARPPLSALAPPHGSPDPPVPELLTGR 852
Query: 847 QRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDS 906
++GR G G LR + +A + S+ P +
Sbjct: 853 GSGKRGRRGG---------GGLRGINGEARPARGRKPGSRREPGRLAL------------ 891
Query: 907 PLTTEIPNKWGPRLGRDAEGTELSRR-HNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFS 965
KWG R G + + RR H+W + +A P + P P +
Sbjct: 892 --------KWGTRGGFNGQMERSPRRTHHW---QHNGELAEGGAEPKDPPPPGPHSEDLK 940
Query: 966 SPPSPSNK-REEEEEEFNFEVIPPPPEFSN--------DPEPPAPALQYLGRQSSPPRNN 1016
PP K R ++N P SN +P P A A L ++ P R
Sbjct: 941 VPPGVVRKSRRGRRRKYN------PTRNSNSSRQDITLEPSPTARAAVPLPPRARPGRPA 994
Query: 1017 YSDLRQL 1023
+ R+L
Sbjct: 995 KNKRRKL 1001
Score = 90.1 bits (222), Expect = 1e-17
Identities = 179/688 (26%), Positives = 232/688 (33%), Gaps = 158/688 (22%)
Query: 82 LPLNAQE-NHGLAVPTPSVPDDFADKEVTGTSSLVNGNLRLYSSVGDLRPGQYGQDLLIP 140
+ LNA N G A+ + VP D SS + L+ + D L P
Sbjct: 220 ISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLF----------HCSDALTP 269
Query: 141 PP---------PPGPAPGPPQD--------ISEPPGGSPLPSPPSTAPPPPPLLLE---- 179
PP PGPA PP + P GG+P P P LL
Sbjct: 270 PPLPPSNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAK 329
Query: 180 ----PPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFL----------- 224
P PPPS P +A S H+ S P P PP F
Sbjct: 330 AQHPPLPPPSTLQGRRPRAQAPSASHSSSL----RPSQRRPRRPPTVFRLLEGRGPQTPR 385
Query: 225 -------APPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPP 277
AP P P P P P P + P G + SD + N ++A PP
Sbjct: 386 RSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSH--SDGSFNLLGSDAHLPPPP 443
Query: 278 R----SPAEPKGSALGPNPEPHLTFPRSFKVP-PPTPVRTSSIPVQEAQEAPRKEEGATK 332
SP +P+ + P+ P T VP P P S PV + EG
Sbjct: 444 TLSSGSPPQPR-HPIQPSL-PGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGM 501
Query: 333 KAPSRLPLPPSFHIRPASQVYPDRAPEPDC-------PGELKATA--------PASPRLG 377
A PLPP + +P +PE PG L A P SP L
Sbjct: 502 GAGPACPLPPL----AGGEAFPFPSPEQGLALSGAGFPGMLGALPLPLSLGQPPPSPLLN 557
Query: 378 QSQSQADERAGTPPPAPP-LPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKS 436
S G PP P LPPP P PP AP P P L A PP+
Sbjct: 558 HSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPG-EPEGPSLLVASLLPPPPSD------- 609
Query: 437 SSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTV 496
L P P+ P AS P+ P+ + E +A G GP+
Sbjct: 610 ----LLPPPSAPPSNLLASFLPLLALGPTAGD---GEGSAEGAG------------GPSG 650
Query: 497 APQSKEGKKG----PRLPEKETLLSL----------PAKDTPP-----GVPEKSLGGSSL 537
P S G P L TL++L P TPP P+ SS+
Sbjct: 651 EPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSV 710
Query: 538 TETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARL-----SSAAEKEAKPSIGSLPPK 592
T P + S+ P +S P + + L A L S + A PS+ PP
Sbjct: 711 TTATTDPGAS--SLGKAPSNSGRPP-QLLSPLLGASLLGDLSSLTSSPGALPSL-LQPPG 766
Query: 593 PRLEGG---RICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKA---- 645
P L G ++ G LS+ + LL + + P+ P +PP++
Sbjct: 767 PLLSGQLGLQLLPGGGAPPPLSEASS-----PLACLLQSLQIPPEQPEAPCLPPESPASA 821
Query: 646 -TPEPAIPPKATLWPATPPKATLGPATP 672
PEPA PP + L PP + P P
Sbjct: 822 LEPEPARPPLSAL---APPHGSPDPPVP 846
Score = 75.5 bits (184), Expect = 3e-13
Identities = 224/944 (23%), Positives = 301/944 (31%), Gaps = 172/944 (18%)
Query: 277 PRSPAEPKGSALGPNPEPHLT---FPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKK 333
P +P P G+ +GP E +T R V T R+ + EGA+ +
Sbjct: 78 PLAPVTPGGAGVGPASEEDMTKLCNHRRKAVAMATLYRSMETTCSHSSPG----EGASPQ 133
Query: 334 APSRL-PLPPSFHIRPASQVYPDRAPEPDCPGELKATAPA---------------SPRL- 376
+ P PPS RP +V P P PG L P+ PRL
Sbjct: 134 MFHTVSPGPPS--ARPPCRV-PPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLA 190
Query: 377 ------GQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGF 430
G S + R P PAPP PPPA L P+ A PPA
Sbjct: 191 DPVPSGGSSSPRFLPRGNAPSPAPP-PPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPH 249
Query: 431 TKTPKSSSP-------ALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRR 483
+ S P AL P P PPS A P + P + L
Sbjct: 250 ASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPAS-QPPVSSATMHLPLVL------- 301
Query: 484 EDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGG--------- 534
GP + EG P L + PP P +L G
Sbjct: 302 ---------GPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPS 352
Query: 535 ----SSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSS-----AAEKEAKPS 585
SSL ++ P P+V + + + R+ R A + + PS
Sbjct: 353 ASHSSSLRPSQRRPRRP-PTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPS 411
Query: 586 IGSL----PPKPRLEGGRICENGADDDKLSKP-VAKNLPPQ-----STTLLPTTSLQPKA 635
+ SL P P G G+D P ++ PPQ +L TTS +
Sbjct: 412 VLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSS 471
Query: 636 MLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATPLKATSGPTTPLKATSGPAIASTA 695
+ G PP A+ P +P P+ GPA PL +G + +A +
Sbjct: 472 VPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSG 531
Query: 696 TTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFP 755
P L G P P G G P LP G
Sbjct: 532 AGFPGMLGALPLPLSLGQ--PPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPG----- 584
Query: 756 PKTSPGGGEVPCLY--------------KPHCHQSSLSREVAVVMPTLARGGAAGPGE-- 799
P +PG E P L P S+L +A +P LA G AG GE
Sbjct: 585 PPLAPGEPEGPSLLVASLLPPPPSDLLPPPSAPPSNL---LASFLPLLALGPTAGDGEGS 641
Query: 800 PVEVKEPPGLPAK----------PPASAQPTDELLRHPVTGEVVERGS---PMALLLAAR 846
P G P PP SA PT L + ++ S P +L+A
Sbjct: 642 AEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAP 701
Query: 847 QRAQKGRSVGAAL---GRSSLPGSLRDHSHQAEASSDSIFHS-QGTPNSFTVVP-KLPKE 901
Q SV A G SSL + + + S + S G +S T P LP
Sbjct: 702 QPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGALPSL 761
Query: 902 AEKDSPLTT-EIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPL 960
+ PL + ++ + P G +E S P A + P P+ L
Sbjct: 762 LQPPGPLLSGQLGLQLLPGGGAPPPLSEAS--------SPLACLLQSLQIPPEQPEAPCL 813
Query: 961 PKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDL 1020
P P SP++ E E + PP P+PP P L R L
Sbjct: 814 P-----PESPASALEPEPARPPLSALAPP---HGSPDPPVPELLTGRGSGKRGRRGGGGL 865
Query: 1021 RQLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGEPHRGPGLPH- 1079
R + A PA G R P R G L+ + GG + G+ R P H
Sbjct: 866 RGINGE---ARPARG--RKPGSRREPGRLALKWGTRGG--------FNGQMERSPRRTHH 912
Query: 1080 ----GGTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPGGLHAPR 1119
G + P P P GP + + PPG + R
Sbjct: 913 WQHNGELAEGGAEPK--DPPPPGPHSEDL----KVPPGVVRKSR 950
>gi|221139926 NHS-like 1 [Homo sapiens]
Length = 1606
Score = 95.5 bits (236), Expect = 3e-19
Identities = 137/516 (26%), Positives = 204/516 (39%), Gaps = 81/516 (15%)
Query: 62 SESGTATLKARPRVRPLLTFLPLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNLRL 121
S+S T T + P+ FL + N G P P VP+ + + S+ + + L
Sbjct: 854 SQSNTPTA-----LTPVPVFLKSVSPAN-GKGKPKPKVPE--RKSSLISSVSISSSSTSL 905
Query: 122 YSSVGDLRPGQYGQ-DLLI---PPPPPGPAPGPPQDISEPPGGSPL--PSPPST-----A 170
SS G + D + P PPP P P PP P SP P PP T +
Sbjct: 906 SSSTSTEGSGTMKKLDPAVGSPPAPPPPPVPSPPFPC--PADRSPFLPPPPPVTDCSQGS 963
Query: 171 PPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPP 230
P P + PPPP ++ P P LSPP SP +P P +P PPL P
Sbjct: 964 PLPHSPVFPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLL-----PSS 1018
Query: 231 VPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGP 290
P PAPP TR PP N Q E++R S R P+ + ++ P
Sbjct: 1019 EPPPAPPLDPK-FMKDTR--PP----------FTNSGQPESSRGS-LRPPSTKEETSRPP 1064
Query: 291 NPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPAS 350
P L + ++ PVR +S A+ A E A ++ R P+ P +H++P++
Sbjct: 1065 MP---LITTEALQMVQLRPVRKNS----GAEAAQLSERTAQEQ---RTPVAPQYHLKPSA 1114
Query: 351 QVYP-DRAPEPDCPGELKATAPASPRLGQSQSQAD-----ERAGTPPPAPPLPPPAPPLP 404
+ + E + + + + P +S SQ D ER G +P P
Sbjct: 1115 FLKSRNSTNEMESESQPASVTSSLPTPAKSSSQGDHGSAAERGGPVSRSPGAPSAGEAEA 1174
Query: 405 PPAP---PLPPAAP---PLPCAQK------AAHPPAGFTKTP-KSSSPALKPKPNP---- 447
P+P PLP ++P P P ++K P F P ++ S AL+ P+P
Sbjct: 1175 RPSPSTTPLPDSSPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPSPTTGE 1234
Query: 448 -------PSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQS 500
+ E++A+ A P L A + SR E +P + AP+
Sbjct: 1235 EGSVHSREAKESSAAQAGSHATHPG-TSVLEGGAAGSMSPSRVEANVPMVQPDVSPAPKQ 1293
Query: 501 KEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSS 536
+E + + L +D GVPE + GSS
Sbjct: 1294 EEPAENSADTGGDGESCLSQQDGAAGVPETNAAGSS 1329
Score = 68.6 bits (166), Expect = 3e-11
Identities = 122/463 (26%), Positives = 155/463 (33%), Gaps = 112/463 (24%)
Query: 126 GDLRPGQYGQDLLIPPPPPG---PAPGPPQD----ISEPPGGSPLPSPPSTAPPPPPLLL 178
G +R Q G +P P G P P+ IS G S + P+ P P L
Sbjct: 811 GPVRHVQEGSRATMPQVPGGSVKPKIMSPEKSHRVISPSSGYSSQSNTPTALTPVPVFLK 870
Query: 179 EPPPPPSMAPPPPPVLE---------ALSPPHTLSSPSIPTPP-------DFIPPAPPLA 222
P P P V E ++S T S S T D +PP
Sbjct: 871 SVSPANGKGKPKPKVPERKSSLISSVSISSSSTSLSSSTSTEGSGTMKKLDPAVGSPP-- 928
Query: 223 FLAPPPPPVPAPAPPAPA--SPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASP-PRS 279
APPPPPVP+P P PA SP L PP VT + ++ SP P S
Sbjct: 929 --APPPPPVPSPPFPCPADRSPF-----LPPPPPVT-------------DCSQGSPLPHS 968
Query: 280 PAEPKGSALGPNPEPHLTF--PRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSR 337
P P P PE + F P + + PP P + +P +P
Sbjct: 969 PVFPP-----PPPEALIPFCSPPDWCLSPPRPALSPILP----------------DSPVS 1007
Query: 338 LPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLP 397
LPLPP + P+S+ P AP D P +K T P GQ +S
Sbjct: 1008 LPLPPP--LLPSSE--PPPAPPLD-PKFMKDTRPPFTNSGQPESSRGS------------ 1050
Query: 398 PPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSA 457
L PP+ + PP+P A K+S + E A
Sbjct: 1051 -----LRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSERTAQEQRTPVA 1105
Query: 458 PVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLS 517
P PS K RN S+ S PT A S +G G
Sbjct: 1106 PQYHLKPSAFLKSRNSTNEMESESQPASVTSSL---PTPAKSSSQGDHGSAAER------ 1156
Query: 518 LPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPT 560
G +S G S E EA PS PS +P SP+
Sbjct: 1157 -------GGPVSRSPGAPSAGEAEARPS---PSTTPLPDSSPS 1189
Score = 54.7 bits (130), Expect = 5e-07
Identities = 198/910 (21%), Positives = 287/910 (31%), Gaps = 242/910 (26%)
Query: 323 APRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGE----LKATAPASPRLGQ 378
+P + P+ L P F ++ S P+P P + + + +S
Sbjct: 847 SPSSGYSSQSNTPTALTPVPVF-LKSVSPANGKGKPKPKVPERKSSLISSVSISSSSTSL 905
Query: 379 SQSQADERAGTPPPAPPL--PPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKS 436
S S + E +GT P PPAPP PPP P +PP PC P
Sbjct: 906 SSSTSTEGSGTMKKLDPAVGSPPAPP-PPPVP-----SPPFPC--------------PAD 945
Query: 437 SSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTV 496
SP L P PP + + +P L H P V
Sbjct: 946 RSPFLPP---PPPVTDCSQGSP-----------------------------LPHSP---V 970
Query: 497 APQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQ 556
P P + LS P P +P+ + SL LP +P
Sbjct: 971 FPPPPPEALIPFCSPPDWCLSPPRPALSPILPDSPV------------SLPLPP-PLLPS 1017
Query: 557 DSPTPSVR---QIRNELEARLSSAAEKEAKPSIGSL-PPKPRLEGGRICENGADDDKLSK 612
P P+ + + +++ + E+ S GSL PP + E R
Sbjct: 1018 SEPPPAPPLDPKFMKDTRPPFTNSGQPES--SRGSLRPPSTKEETSR------------- 1062
Query: 613 PVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATP--PKATLGPA 670
PP L+ T +LQ L P + + TP P+ L P+
Sbjct: 1063 ------PPMP--LITTEALQ-MVQLRPVRKNSGAEAAQLSERTAQEQRTPVAPQYHLKPS 1113
Query: 671 TPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQ 730
LK+ + T +++ S PA +++ P +S ++ D G A + P S+ PS
Sbjct: 1114 AFLKSRNS-TNEMESESQPASVTSSLPTPAKSS---SQGDHGSAAERGGPVSRSPGAPSA 1169
Query: 731 ARGEGSPSEAT---------RLPTQGARSSAAF----PPK------------------TS 759
E PS +T R P ++ F PP+ S
Sbjct: 1170 GEAEARPSPSTTPLPDSSPSRKPPPISKKPKLFLVVPPPQKDFAVEPAENVSEALRAVPS 1229
Query: 760 PGGGEVPCLYKPHCHQSSLSREVAVVM---PTLARGGAAGPGEP--VEVKEPPGLPAKPP 814
P GE ++ +SS ++ + ++ GGAAG P VE P P P
Sbjct: 1230 PTTGEEGSVHSREAKESSAAQAGSHATHPGTSVLEGGAAGSMSPSRVEANVPMVQPDVSP 1289
Query: 815 ASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQ 874
A Q P G + L +Q+ + G ++
Sbjct: 1290 APKQ------EEPAENSADTGGDGESCL------SQQDGAAGV------------PETNA 1325
Query: 875 AEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHN 934
A +SS++ + N + P P+ E L I LGR + SR H+
Sbjct: 1326 AGSSSEACDFLKEDGNDEVMTPSRPRTTE---DLFAAIHRSKRKVLGRRDSDDDHSRNHS 1382
Query: 935 WTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIP------- 987
P PV APS PK S K + F ++
Sbjct: 1383 -----PSPPVTPTGAAPSLAS-----PKQVGSIQRSIRKSSTSSDNFKALLLKKGSRSDT 1432
Query: 988 ------------PPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPALG 1035
P F P+P SP +N + N G P +L
Sbjct: 1433 SARMSAAEMLKNTDPRFQRSRSEPSPDAPESPSSCSPSKNRRAQEEWAKNEGL-MPRSLS 1491
Query: 1036 FSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGEPHRGPGLPHGGTGRSLSSPNCFGPQ 1095
FS G RY GRS P + R SSP +
Sbjct: 1492 FS----GPRY------------GRS--------RTPPSAASSRYSMRNRIQSSPMTVISE 1527
Query: 1096 PGGPEMRRVNSAGRAPPGGLHAPRLSLEGAAR-------------GAAEAKHKAPGSADY 1142
G + V+S R G A SL+G AR AA + +APG D
Sbjct: 1528 GEGEAVEPVDSIARGALGA--AEGCSLDGLAREEMDEGGLLCGEGPAASLQPQAPGPVD- 1584
Query: 1143 GFAPAAGRSP 1152
G A A GR P
Sbjct: 1585 GTASAEGREP 1594
Score = 34.3 bits (77), Expect = 0.73
Identities = 78/394 (19%), Positives = 129/394 (32%), Gaps = 86/394 (21%)
Query: 520 AKDTPPGVPEKSLGGS---SLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARLSS 576
++ T P VP GGS + E + + PS Y Q + ++ + L
Sbjct: 820 SRATMPQVP----GGSVKPKIMSPEKSHRVISPSSGYSSQSNTPTALTPVPVFL------ 869
Query: 577 AAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTS------ 630
K P+ G PKP++ + K S + ++ ST+L +TS
Sbjct: 870 ---KSVSPANGKGKPKPKVP----------ERKSSLISSVSISSSSTSLSSSTSTEGSGT 916
Query: 631 ---LQPKAMLGPAIPPKATPEPAIP------------------------PKATLWPATPP 663
L P PA PP P P P P + ++P PP
Sbjct: 917 MKKLDPAVGSPPAPPPPPVPSPPFPCPADRSPFLPPPPPVTDCSQGSPLPHSPVFPPPPP 976
Query: 664 KAT----------LGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGP 713
+A L P P + P +P+ P + ++ P KD+ P
Sbjct: 977 EALIPFCSPPDWCLSPPRPALSPILPDSPVSLPLPPPLLPSSEPPPAPPLDPKFMKDTRP 1036
Query: 714 ----AGQPEKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLY 769
+GQPE +S+ P + E S + T+ + P + + G
Sbjct: 1037 PFTNSGQPE--SSRGSLRPPSTKEETSRPPMPLITTEALQMVQLRPVRKNSGAEAAQLSE 1094
Query: 770 KPHCHQSSLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVT 829
+ Q + + P+ E +P + + P A+ + +
Sbjct: 1095 RTAQEQRTPVAPQYHLKPSAFLKSRNSTNEMESESQPASVTSSLPTPAKSSSQ----GDH 1150
Query: 830 GEVVERGSPMALLLAARQRAQKGRSVGAALGRSS 863
G ERG P++ R+ S G A R S
Sbjct: 1151 GSAAERGGPVS-------RSPGAPSAGEAEARPS 1177
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 95.5 bits (236), Expect = 3e-19
Identities = 151/650 (23%), Positives = 214/650 (32%), Gaps = 102/650 (15%)
Query: 145 GPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPS----MAPPPPPVLEALSPP 200
G + GP + PP P P PP + P P EP P + AP PP P
Sbjct: 150 GLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAP 209
Query: 201 HTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKS 260
P P P + P L+ PP P + +VG P GG
Sbjct: 210 -----PGAPPPHPQLYPGGTGGVLSGPP-----MGPKGGGAASSVGG---PNGGKQHPPP 256
Query: 261 DVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPR-SFKVPPPTPVRTSSIPVQE 319
++ + A+ A P + P P G P+ P FP + +PPP +R P+
Sbjct: 257 TTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALR----PLNN 312
Query: 320 AQEAPRKEEGATKKAPSRLPLPPSF-----HIRPASQVYPDRAPEPDCPGELKATAPASP 374
A +P + P LP P + + P + P AP P ++APA P
Sbjct: 313 ASASP--PGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPP 370
Query: 375 ------------RLGQSQSQADERAGTPPPAPPLPPPAP-PLPPPA-------PP--LPP 412
S S + + +P PA P P PPP PP P
Sbjct: 371 MRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQP 430
Query: 413 AAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRN 472
+ P + PP + + +S+ P P ++TA Q ++ +
Sbjct: 431 SLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQ 490
Query: 473 ELAAYLCGSRREDRFLSHRPGPTVAPQSKEG---------------------KKGP-RLP 510
+ +++ S P P P EG GP LP
Sbjct: 491 QQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLP 550
Query: 511 EKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDS-----PTPSVRQ 565
+ +S ++ P G P S SS + ++ + + PS PQ + P P+V
Sbjct: 551 PPHSQVSY-SQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTT 609
Query: 566 IRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTL 625
L +++ A A S PP P G R GA PP T
Sbjct: 610 SSATLSTVIATVASSPAGYKTAS-PPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRT- 667
Query: 626 LPTTSLQPKAMLGPAIPP--KATPEPAIPPKATLWPATPP--KATLGPATPLKATSGPTT 681
PP + T PA P T P +P L PA P S P
Sbjct: 668 --------------GTPPGYRGTSPPAGP--GTFKPGSPTVGPGPLPPAGPSGLPSLPPP 711
Query: 682 PLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQA 731
P SGP +++T E PA P P + V PS A
Sbjct: 712 PAAPASGPPLSATQIKQEPAEEYETPESPVPPARSP-SPPPKVVDVPSHA 760
Score = 90.5 bits (223), Expect = 9e-18
Identities = 253/1049 (24%), Positives = 344/1049 (32%), Gaps = 219/1049 (20%)
Query: 147 APGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSP 206
+PG ++ S+ G L P+ PPPL P PP P P EA PH P
Sbjct: 137 SPGSVENDSDSSSG--LSQGPARPYHPPPLFPPSPQPPDSTPRQP---EASFEPH----P 187
Query: 207 SIPTPPDFIPPAPPLAFLAPPPPPVPAPAP---PAPASPHTVGTRLFPPGGVTKWKSDVA 263
S+ P PP + + PP P P P P G + P GG
Sbjct: 188 SVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGP 247
Query: 264 LNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEA 323
G+Q PP +P S P PP TPV ++P A
Sbjct: 248 NGGKQHP-----PPTTPISVSSSGASGAPPTK---------PPTTPVGGGNLP-----SA 288
Query: 324 PRKEEGATKKAPSRLP-----LPPSFHIRP---ASQVYPDRAPEPDCPGELKATAPASPR 375
P P+ P LPP +RP AS P +P PG L P+
Sbjct: 289 P---------PPANFPHVTPNLPPPPALRPLNNASASPPGLGAQP-LPGHL----PSPHA 334
Query: 376 LGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAA-HPPAGFTKTP 434
+GQ PP P P L P+ LP A +A PP F +
Sbjct: 335 MGQGMGGL-----------------PPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSS 377
Query: 435 KSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGP 494
SSS A + S ++AS P PS P P
Sbjct: 378 SSSSSA-AASSSSSSSSSSASPFPASQALPSYPHSF---------------------PPP 415
Query: 495 TVAPQSKEGKKGPRLPEKETLLSLPAKDT-PPGVPEKSLGGSSLTETEAAPSLTLPSVDY 553
T S + P K T SLP++ G P G L + A P PS
Sbjct: 416 TSLSVSNQ-------PPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGA 468
Query: 554 IPQDSPTPSV----RQIRNELEARLSSAAEKEAKPSIGSLPPKP-----RLEGGRICENG 604
P S Q + + + + +++ + S PP P LEGG
Sbjct: 469 QSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAH 528
Query: 605 ADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPP-KATPEPAIPPKATLWPATPP 663
S + PP L P S + GP PP ++ + +P + P
Sbjct: 529 PYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHP 588
Query: 664 KATLGP-ATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQP----- 717
+ GP P P P TS A+ +T + T S K + P G P
Sbjct: 589 SPSQGPQGAPYPF---PPVPTVTTSS---ATLSTVIATVASSPAGYKTASPPGPPPYGKR 642
Query: 718 -EKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQS 776
P + + +TP + PS T P G R TSP G P +KP
Sbjct: 643 APSPGAYKTATPPGYKPGSPPSFRTGTP-PGYRG-------TSPPAG--PGTFKPG---- 688
Query: 777 SLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERG 836
PT+ GPG P+ P GLP+ PP A P G
Sbjct: 689 ---------SPTV------GPG-PLPPAGPSGLPSLPPPPAAPAS--------------G 718
Query: 837 SPMALLLAARQRAQKGRS----VGAALGRSSLPGSLRDHSHQAEASS-----DSIFHSQG 887
P++ ++ A++ + V A S P + SH ++++ D F+S
Sbjct: 719 PPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCA 778
Query: 888 TPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRL------GRDAEGTELSRRHNWTKPEPQ 941
+ + V + K A+K + L ++ + R R+ E + R + E
Sbjct: 779 RSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKEREREREREKEREREKERELERS 838
Query: 942 APVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAP 1001
+A E AP P P+P PP E V PP P P
Sbjct: 839 VKLAQEGRAPVECPSLGPVP---HRPPF----------EPGSAVATVPPYLG----PDTP 881
Query: 1002 ALQYLGRQS-----SPPRNNYSDLRQLPNAGPGA----PPALGFSRFPAG---ARYAGAG 1049
AL+ L + SP N+ L PG PAL +S PA R A
Sbjct: 882 ALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLLGYNVPAL-YSSDPAAREREREARER 940
Query: 1050 GLERFSGGGRSLIKKRLYVGEPHRGPGLP----HGGTGRSLSSPNCFGPQPGGPEMRRVN 1105
L G + L GPGL HGG P P P P + +
Sbjct: 941 DLRDRLKPGFEVKPSELEPLHGVPGPGLDPFPRHGGLALQPGPPG-LHPFPFHPSLGPLE 999
Query: 1106 SAGRAPPGGLHAPRLSLEGAARGAAEAKH 1134
A G A R + A R AAE +H
Sbjct: 1000 RERLALAAG-PALRPDMSYAERLAAERQH 1027
Score = 71.2 bits (173), Expect = 5e-12
Identities = 122/527 (23%), Positives = 165/527 (31%), Gaps = 95/527 (18%)
Query: 125 VGDLRPGQYGQDLLIP-----PPPPGPAPGPPQDI---------------SEPPGGSPLP 164
+G L PG L P PP AP PP S S P
Sbjct: 339 MGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASP 398
Query: 165 SPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDF---------- 214
P S A P P PP S++ PP + P + S P PP +
Sbjct: 399 FPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAH 458
Query: 215 ---IPPA--------PPLAF---------------------------LAPPPPPVPAPAP 236
PP+ PP++ + PPPP P P
Sbjct: 459 PGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHP 518
Query: 237 ----------PAPASPHTVGTRLFPPG--GVTKWKSDVALN--GRQAEATRASPPRSPAE 282
P SP R +PPG + S V+ + G +S S +
Sbjct: 519 LEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSST 578
Query: 283 PKGSALGPNPEPHLTFPRSFKVP-PPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLP 341
+GS +P P P+ P PP P T+S A A K S P
Sbjct: 579 SQGSYPCSHPSPS-QGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPP 637
Query: 342 PSFHIRPASQVYPDRAP---EPDCPGELKATAP-----ASPRLGQSQSQADERAGTPPPA 393
P P+ Y P +P P + P SP G + P P
Sbjct: 638 PYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPL 697
Query: 394 PPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENT 453
PP P P PP P P + PPL Q PA +TP+S P + PP +
Sbjct: 698 PPAGPSGLPSLPPPPAAPASGPPLSATQ-IKQEPAEEYETPESPVPPARSPSPPPKVVDV 756
Query: 454 ASSAPVDWRDPSQMEKLRNELA-AYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEK 512
S A R +++ N A + L E L+ + V +E ++ R EK
Sbjct: 757 PSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAR-EEK 815
Query: 513 ETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSP 559
E + E+ L S E + PS+ +P P
Sbjct: 816 EREREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRPP 862
Score = 53.5 bits (127), Expect = 1e-06
Identities = 175/859 (20%), Positives = 252/859 (29%), Gaps = 189/859 (22%)
Query: 252 PGGVTKWKSDVALN-----GRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPP 306
PGGV+ SD ++A AS P+ + + + + P+ K
Sbjct: 35 PGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQ 94
Query: 307 PTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGEL 366
P S + ++G++ R Q +P PG +
Sbjct: 95 ELPRPQSPSDLDSLDGRSLNDDGSSDP-------------RDIDQDNRSTSPSIYSPGSV 141
Query: 367 KATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHP 426
+ + +S L Q ++ PP+P P P P + P+ P P
Sbjct: 142 ENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPP 201
Query: 427 PAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDR 486
+ + P + P P+ P S P+ + AA G +
Sbjct: 202 TSRMFQAPPGAPPP-HPQLYPGGTGGVLSGPPMGPKGGG---------AASSVGGPNGGK 251
Query: 487 FLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSL 546
H P T S G G + P K PP P +GG +L A P
Sbjct: 252 --QHPPPTTPISVSSSGASG----------APPTK--PPTTP---VGGGNL--PSAPPPA 292
Query: 547 TLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGAD 606
P V P P P++R + N + P +G+ P L G
Sbjct: 293 NFPHV--TPNLPPPPALRPLNN----------ASASPPGLGAQPLPGHLPSPHAMGQGMG 340
Query: 607 DDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEP-AIPPKATLWPATPPKA 665
LPP GP P P P ++PP ++ PA P +
Sbjct: 341 ----------GLPP-----------------GPEKGPTLAPSPHSLPPASSSAPAPPMRF 373
Query: 666 TLGPATPLK-ATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQE 724
++ A S ++ +++ P AS A LP+ + QP P +
Sbjct: 374 PYSSSSSSSAAASSSSSSSSSSASPFPASQA--LPSYPHSFPPPTSLSVSNQP--PKYTQ 429
Query: 725 VSTPSQA---RGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSRE 781
S PSQA +G P RL FPP T P + H H ++
Sbjct: 430 PSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQ 489
Query: 782 VAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMAL 841
+ + ++ G PP A P HP+ G P A+
Sbjct: 490 QQQQQQ-----------QQQQQQQHHGNSGPPPPGAFP------HPLEGGSSHHAHPYAM 532
Query: 842 LLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKE 901
S GSLR P P
Sbjct: 533 --------------------SPSLGSLR--------------------------PYPPGP 546
Query: 902 AEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLP 961
A P + ++ GP G +S N + Q +PS PQG P P
Sbjct: 547 AHLPPPHSQVSYSQAGP------NGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYP 600
Query: 962 KSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLR 1021
PP P+ + P PP P Y R SP +
Sbjct: 601 ----FPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPP-PYGKRAPSPGAYKTA--- 652
Query: 1022 QLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGEPHRGPG-LPHG 1080
P PG+PP+ P G G +G G G P GPG LP
Sbjct: 653 TPPGYKPGSPPSFRTGTPP------GYRGTSPPAGPG------TFKPGSPTVGPGPLPPA 700
Query: 1081 GTGRSLSSPNCFGPQPGGP 1099
G S P P P P
Sbjct: 701 GPSGLPSLP----PPPAAP 715
Score = 51.6 bits (122), Expect = 4e-06
Identities = 53/173 (30%), Positives = 64/173 (36%), Gaps = 22/173 (12%)
Query: 83 PLNAQENHGLAVPTPSVPDDFADKEVTGTS-SLVNGNLRLYSSVGDLRPGQYGQDLLIP- 140
P +Q G P P VP T + V + Y + P YG+ P
Sbjct: 588 PSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPG 647
Query: 141 ----PPPPGPAPGPPQDI--SEPPG--GSPLPSPPSTAPPPPPLLLE---PPPPPSMAP- 188
PPG PG P PPG G+ P+ P T P P + PP PS P
Sbjct: 648 AYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPS 707
Query: 189 -PPPPVLEALSPPHTLSSPSIPTPP-----DFIPPAPPLAFLAPPPPPVPAPA 235
PPPP A PP LS+ I P P PP +PPP V P+
Sbjct: 708 LPPPPAAPASGPP--LSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPS 758
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 95.5 bits (236), Expect = 3e-19
Identities = 151/650 (23%), Positives = 214/650 (32%), Gaps = 102/650 (15%)
Query: 145 GPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPS----MAPPPPPVLEALSPP 200
G + GP + PP P P PP + P P EP P + AP PP P
Sbjct: 150 GLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAP 209
Query: 201 HTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKS 260
P P P + P L+ PP P + +VG P GG
Sbjct: 210 -----PGAPPPHPQLYPGGTGGVLSGPP-----MGPKGGGAASSVGG---PNGGKQHPPP 256
Query: 261 DVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPR-SFKVPPPTPVRTSSIPVQE 319
++ + A+ A P + P P G P+ P FP + +PPP +R P+
Sbjct: 257 TTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALR----PLNN 312
Query: 320 AQEAPRKEEGATKKAPSRLPLPPSF-----HIRPASQVYPDRAPEPDCPGELKATAPASP 374
A +P + P LP P + + P + P AP P ++APA P
Sbjct: 313 ASASP--PGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPP 370
Query: 375 ------------RLGQSQSQADERAGTPPPAPPLPPPAP-PLPPPA-------PP--LPP 412
S S + + +P PA P P PPP PP P
Sbjct: 371 MRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQP 430
Query: 413 AAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRN 472
+ P + PP + + +S+ P P ++TA Q ++ +
Sbjct: 431 SLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQ 490
Query: 473 ELAAYLCGSRREDRFLSHRPGPTVAPQSKEG---------------------KKGP-RLP 510
+ +++ S P P P EG GP LP
Sbjct: 491 QQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLP 550
Query: 511 EKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDS-----PTPSVRQ 565
+ +S ++ P G P S SS + ++ + + PS PQ + P P+V
Sbjct: 551 PPHSQVSY-SQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTT 609
Query: 566 IRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLPPQSTTL 625
L +++ A A S PP P G R GA PP T
Sbjct: 610 SSATLSTVIATVASSPAGYKTAS-PPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRT- 667
Query: 626 LPTTSLQPKAMLGPAIPP--KATPEPAIPPKATLWPATPP--KATLGPATPLKATSGPTT 681
PP + T PA P T P +P L PA P S P
Sbjct: 668 --------------GTPPGYRGTSPPAGP--GTFKPGSPTVGPGPLPPAGPSGLPSLPPP 711
Query: 682 PLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQEVSTPSQA 731
P SGP +++T E PA P P + V PS A
Sbjct: 712 PAAPASGPPLSATQIKQEPAEEYETPESPVPPARSP-SPPPKVVDVPSHA 760
Score = 90.5 bits (223), Expect = 9e-18
Identities = 253/1049 (24%), Positives = 344/1049 (32%), Gaps = 219/1049 (20%)
Query: 147 APGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSP 206
+PG ++ S+ G L P+ PPPL P PP P P EA PH P
Sbjct: 137 SPGSVENDSDSSSG--LSQGPARPYHPPPLFPPSPQPPDSTPRQP---EASFEPH----P 187
Query: 207 SIPTPPDFIPPAPPLAFLAPPPPPVPAPAP---PAPASPHTVGTRLFPPGGVTKWKSDVA 263
S+ P PP + + PP P P P P G + P GG
Sbjct: 188 SVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGP 247
Query: 264 LNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEA 323
G+Q PP +P S P PP TPV ++P A
Sbjct: 248 NGGKQHP-----PPTTPISVSSSGASGAPPTK---------PPTTPVGGGNLP-----SA 288
Query: 324 PRKEEGATKKAPSRLP-----LPPSFHIRP---ASQVYPDRAPEPDCPGELKATAPASPR 375
P P+ P LPP +RP AS P +P PG L P+
Sbjct: 289 P---------PPANFPHVTPNLPPPPALRPLNNASASPPGLGAQP-LPGHL----PSPHA 334
Query: 376 LGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAA-HPPAGFTKTP 434
+GQ PP P P L P+ LP A +A PP F +
Sbjct: 335 MGQGMGGL-----------------PPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSS 377
Query: 435 KSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGP 494
SSS A + S ++AS P PS P P
Sbjct: 378 SSSSSA-AASSSSSSSSSSASPFPASQALPSYPHSF---------------------PPP 415
Query: 495 TVAPQSKEGKKGPRLPEKETLLSLPAKDT-PPGVPEKSLGGSSLTETEAAPSLTLPSVDY 553
T S + P K T SLP++ G P G L + A P PS
Sbjct: 416 TSLSVSNQ-------PPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGA 468
Query: 554 IPQDSPTPSV----RQIRNELEARLSSAAEKEAKPSIGSLPPKP-----RLEGGRICENG 604
P S Q + + + + +++ + S PP P LEGG
Sbjct: 469 QSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAH 528
Query: 605 ADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPP-KATPEPAIPPKATLWPATPP 663
S + PP L P S + GP PP ++ + +P + P
Sbjct: 529 PYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHP 588
Query: 664 KATLGP-ATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQP----- 717
+ GP P P P TS A+ +T + T S K + P G P
Sbjct: 589 SPSQGPQGAPYPF---PPVPTVTTSS---ATLSTVIATVASSPAGYKTASPPGPPPYGKR 642
Query: 718 -EKPASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQS 776
P + + +TP + PS T P G R TSP G P +KP
Sbjct: 643 APSPGAYKTATPPGYKPGSPPSFRTGTP-PGYRG-------TSPPAG--PGTFKPG---- 688
Query: 777 SLSREVAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERG 836
PT+ GPG P+ P GLP+ PP A P G
Sbjct: 689 ---------SPTV------GPG-PLPPAGPSGLPSLPPPPAAPAS--------------G 718
Query: 837 SPMALLLAARQRAQKGRS----VGAALGRSSLPGSLRDHSHQAEASS-----DSIFHSQG 887
P++ ++ A++ + V A S P + SH ++++ D F+S
Sbjct: 719 PPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNSCA 778
Query: 888 TPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRL------GRDAEGTELSRRHNWTKPEPQ 941
+ + V + K A+K + L ++ + R R+ E + R + E
Sbjct: 779 RSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKEREREREREKEREREKERELERS 838
Query: 942 APVAWERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAP 1001
+A E AP P P+P PP E V PP P P
Sbjct: 839 VKLAQEGRAPVECPSLGPVP---HRPPF----------EPGSAVATVPPYLG----PDTP 881
Query: 1002 ALQYLGRQS-----SPPRNNYSDLRQLPNAGPGA----PPALGFSRFPAG---ARYAGAG 1049
AL+ L + SP N+ L PG PAL +S PA R A
Sbjct: 882 ALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLLGYNVPAL-YSSDPAAREREREARER 940
Query: 1050 GLERFSGGGRSLIKKRLYVGEPHRGPGLP----HGGTGRSLSSPNCFGPQPGGPEMRRVN 1105
L G + L GPGL HGG P P P P + +
Sbjct: 941 DLRDRLKPGFEVKPSELEPLHGVPGPGLDPFPRHGGLALQPGPPG-LHPFPFHPSLGPLE 999
Query: 1106 SAGRAPPGGLHAPRLSLEGAARGAAEAKH 1134
A G A R + A R AAE +H
Sbjct: 1000 RERLALAAG-PALRPDMSYAERLAAERQH 1027
Score = 71.2 bits (173), Expect = 5e-12
Identities = 122/527 (23%), Positives = 165/527 (31%), Gaps = 95/527 (18%)
Query: 125 VGDLRPGQYGQDLLIP-----PPPPGPAPGPPQDI---------------SEPPGGSPLP 164
+G L PG L P PP AP PP S S P
Sbjct: 339 MGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASP 398
Query: 165 SPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDF---------- 214
P S A P P PP S++ PP + P + S P PP +
Sbjct: 399 FPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAH 458
Query: 215 ---IPPA--------PPLAF---------------------------LAPPPPPVPAPAP 236
PP+ PP++ + PPPP P P
Sbjct: 459 PGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHP 518
Query: 237 ----------PAPASPHTVGTRLFPPG--GVTKWKSDVALN--GRQAEATRASPPRSPAE 282
P SP R +PPG + S V+ + G +S S +
Sbjct: 519 LEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSST 578
Query: 283 PKGSALGPNPEPHLTFPRSFKVP-PPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLP 341
+GS +P P P+ P PP P T+S A A K S P
Sbjct: 579 SQGSYPCSHPSPS-QGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPP 637
Query: 342 PSFHIRPASQVYPDRAP---EPDCPGELKATAP-----ASPRLGQSQSQADERAGTPPPA 393
P P+ Y P +P P + P SP G + P P
Sbjct: 638 PYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPL 697
Query: 394 PPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENT 453
PP P P PP P P + PPL Q PA +TP+S P + PP +
Sbjct: 698 PPAGPSGLPSLPPPPAAPASGPPLSATQ-IKQEPAEEYETPESPVPPARSPSPPPKVVDV 756
Query: 454 ASSAPVDWRDPSQMEKLRNELA-AYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEK 512
S A R +++ N A + L E L+ + V +E ++ R EK
Sbjct: 757 PSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAR-EEK 815
Query: 513 ETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSP 559
E + E+ L S E + PS+ +P P
Sbjct: 816 EREREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRPP 862
Score = 53.5 bits (127), Expect = 1e-06
Identities = 175/859 (20%), Positives = 252/859 (29%), Gaps = 189/859 (22%)
Query: 252 PGGVTKWKSDVALN-----GRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPP 306
PGGV+ SD ++A AS P+ + + + + P+ K
Sbjct: 35 PGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQ 94
Query: 307 PTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGEL 366
P S + ++G++ R Q +P PG +
Sbjct: 95 ELPRPQSPSDLDSLDGRSLNDDGSSDP-------------RDIDQDNRSTSPSIYSPGSV 141
Query: 367 KATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHP 426
+ + +S L Q ++ PP+P P P P + P+ P P
Sbjct: 142 ENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPP 201
Query: 427 PAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDR 486
+ + P + P P+ P S P+ + AA G +
Sbjct: 202 TSRMFQAPPGAPPP-HPQLYPGGTGGVLSGPPMGPKGGG---------AASSVGGPNGGK 251
Query: 487 FLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSL 546
H P T S G G + P K PP P +GG +L A P
Sbjct: 252 --QHPPPTTPISVSSSGASG----------APPTK--PPTTP---VGGGNL--PSAPPPA 292
Query: 547 TLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGAD 606
P V P P P++R + N + P +G+ P L G
Sbjct: 293 NFPHV--TPNLPPPPALRPLNN----------ASASPPGLGAQPLPGHLPSPHAMGQGMG 340
Query: 607 DDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEP-AIPPKATLWPATPPKA 665
LPP GP P P P ++PP ++ PA P +
Sbjct: 341 ----------GLPP-----------------GPEKGPTLAPSPHSLPPASSSAPAPPMRF 373
Query: 666 TLGPATPLK-ATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPASQE 724
++ A S ++ +++ P AS A LP+ + QP P +
Sbjct: 374 PYSSSSSSSAAASSSSSSSSSSASPFPASQA--LPSYPHSFPPPTSLSVSNQP--PKYTQ 429
Query: 725 VSTPSQA---RGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSRE 781
S PSQA +G P RL FPP T P + H H ++
Sbjct: 430 PSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQ 489
Query: 782 VAVVMPTLARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVERGSPMAL 841
+ + ++ G PP A P HP+ G P A+
Sbjct: 490 QQQQQQ-----------QQQQQQQHHGNSGPPPPGAFP------HPLEGGSSHHAHPYAM 532
Query: 842 LLAARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKE 901
S GSLR P P
Sbjct: 533 --------------------SPSLGSLR--------------------------PYPPGP 546
Query: 902 AEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLP 961
A P + ++ GP G +S N + Q +PS PQG P P
Sbjct: 547 AHLPPPHSQVSYSQAGP------NGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYP 600
Query: 962 KSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLR 1021
PP P+ + P PP P Y R SP +
Sbjct: 601 ----FPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPP-PYGKRAPSPGAYKTA--- 652
Query: 1022 QLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKRLYVGEPHRGPG-LPHG 1080
P PG+PP+ P G G +G G G P GPG LP
Sbjct: 653 TPPGYKPGSPPSFRTGTPP------GYRGTSPPAGPG------TFKPGSPTVGPGPLPPA 700
Query: 1081 GTGRSLSSPNCFGPQPGGP 1099
G S P P P P
Sbjct: 701 GPSGLPSLP----PPPAAP 715
Score = 51.6 bits (122), Expect = 4e-06
Identities = 53/173 (30%), Positives = 64/173 (36%), Gaps = 22/173 (12%)
Query: 83 PLNAQENHGLAVPTPSVPDDFADKEVTGTS-SLVNGNLRLYSSVGDLRPGQYGQDLLIP- 140
P +Q G P P VP T + V + Y + P YG+ P
Sbjct: 588 PSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPG 647
Query: 141 ----PPPPGPAPGPPQDI--SEPPG--GSPLPSPPSTAPPPPPLLLE---PPPPPSMAP- 188
PPG PG P PPG G+ P+ P T P P + PP PS P
Sbjct: 648 AYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPS 707
Query: 189 -PPPPVLEALSPPHTLSSPSIPTPP-----DFIPPAPPLAFLAPPPPPVPAPA 235
PPPP A PP LS+ I P P PP +PPP V P+
Sbjct: 708 LPPPPAAPASGPP--LSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPS 758
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 95.1 bits (235), Expect = 3e-19
Identities = 86/299 (28%), Positives = 110/299 (36%), Gaps = 54/299 (18%)
Query: 164 PSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAF 223
P+PPS PP + PPP + PP PP+ E+L PP P P PP P+ P
Sbjct: 218 PAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGP--- 274
Query: 224 LAPP--PPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPA 281
PP PPP P PPAP H + + PP G A PP
Sbjct: 275 PGPPQLPPPAPGVHPPAPV-VHPPASGVHPPA-----------PGVHPPAPGVHPPAPGV 322
Query: 282 EPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLP 341
P S + P P P + P + V PP P G AP P
Sbjct: 323 HPPTSGVHP-PAPGV-HPPAPGVHPPAP-------------------GVHPPAPGVHPPA 361
Query: 342 PSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAP 401
P H P++ V+ P PG PA+P + + G PPAP + P AP
Sbjct: 362 PGVHPPPSAGVH------PQAPG----VHPAAPAV------HPQAPGVHPPAPGMHPQAP 405
Query: 402 PLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVD 460
+ P P + P+AP + HP P P L+P P N P +
Sbjct: 406 GVHPQPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLRPPLPSEGPGNIPPPPPTN 464
Score = 91.3 bits (225), Expect = 5e-18
Identities = 94/293 (32%), Positives = 107/293 (36%), Gaps = 63/293 (21%)
Query: 140 PPPPPGPAPGPPQDISEPP----GGSPLPSPPSTAPPPPP--LLLEPPPPPSMAPPPPPV 193
PP PP GPP PP G P P P + PPPPP L L P PP AP PP
Sbjct: 217 PPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPG 276
Query: 194 LEALSPPHTLSSPSI-PTPPDFIPPA----PPLAFLAPPPPPVPAPAP---PAPASPHTV 245
L PP +P + P P PPA PP + PP P V PAP P + H
Sbjct: 277 PPQLPPP----APGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPP 332
Query: 246 GTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVP 305
+ PP A PP P + P P P + P S V
Sbjct: 333 APGVHPP------------------APGVHPPAPGVHPPAPGVHP-PAPGVHPPPSAGVH 373
Query: 306 PPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAP--EPDCP 363
P P + P Q AP G AP P P H +P V+P AP P P
Sbjct: 374 PQAPGVHPAAPAVHPQ-AP----GVHPPAPGMHPQAPGVHPQPPG-VHPS-APGVHPQPP 426
Query: 364 GELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPP 416
G P++P G PP P P PPLP P P PP
Sbjct: 427 G----VHPSNP-------------GVHPPTPMPPMLRPPLPSEGPGNIPPPPP 462
Score = 61.2 bits (147), Expect = 6e-09
Identities = 58/199 (29%), Positives = 66/199 (33%), Gaps = 58/199 (29%)
Query: 256 TKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSI 315
T W + Q PP P+ P G P K PPP P+
Sbjct: 197 THWNRETKQFFLQFHFKMEKPPAPPSLPAG-------------PPGVKRPPP-PLMNGLP 242
Query: 316 PVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPR 375
P P E P LPLPP P P P P P P+
Sbjct: 243 P------RPPLPESLPPPPPGGLPLPPM----------PPTGPAPSGP-------PGPPQ 279
Query: 376 LGQSQSQADERAGTPPPAPPLPPPAPPLPPPA----PPLPPAAPPLPCAQKAAHPPAGFT 431
L PPPAP + PPAP + PPA PP P PP P HPPA
Sbjct: 280 L-------------PPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAP----GVHPPAPGV 322
Query: 432 KTPKSSSPALKPKPNPPSP 450
P S P +PP+P
Sbjct: 323 HPPTSGVHPPAPGVHPPAP 341
Score = 49.7 bits (117), Expect = 2e-05
Identities = 39/126 (30%), Positives = 46/126 (36%), Gaps = 10/126 (7%)
Query: 130 PGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPP 189
PG + + PP PG P P PP P P PP P + PPP + P
Sbjct: 320 PGVHPPTSGVHPPAPGVHPPAPG--VHPPAPGVHPPAPGVHPPAPG--VHPPPSAGVHPQ 375
Query: 190 PPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAP---PAPASPHTVG 246
P V A H + P P P AP + P PP V AP P P H
Sbjct: 376 APGVHPAAPAVHPQAPGVHPPAPGMHPQAPG---VHPQPPGVHPSAPGVHPQPPGVHPSN 432
Query: 247 TRLFPP 252
+ PP
Sbjct: 433 PGVHPP 438
Score = 49.3 bits (116), Expect = 2e-05
Identities = 29/67 (43%), Positives = 33/67 (49%), Gaps = 6/67 (8%)
Query: 130 PGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPP-PLLLEPPPP---PS 185
PG + Q + P PPG P P +PPG PS P PP P P +L PP P P
Sbjct: 398 PGMHPQAPGVHPQPPGVHPSAPGVHPQPPGVH--PSNPGVHPPTPMPPMLRPPLPSEGPG 455
Query: 186 MAPPPPP 192
PPPPP
Sbjct: 456 NIPPPPP 462
Score = 47.0 bits (110), Expect = 1e-04
Identities = 41/135 (30%), Positives = 50/135 (37%), Gaps = 18/135 (13%)
Query: 123 SSVGDLRPGQYGQDLLIPPPPPGP---APG---PPQDISEPPGGSPLPSPPSTAPPPPPL 176
S V PG + + PP PG APG P + PP P P P P +
Sbjct: 327 SGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAV 386
Query: 177 LLEP----PPPPSMAP------PPPPVLEALSPPHTLSSPSI-PTPPDFIPPAPPLAFLA 225
+ PP P M P P PP + +P P + P+ P PP P L
Sbjct: 387 HPQAPGVHPPAPGMHPQAPGVHPQPPGVHPSAPGVHPQPPGVHPSNPGVHPPTPMPPMLR 446
Query: 226 PP-PPPVPAPAPPAP 239
PP P P PP P
Sbjct: 447 PPLPSEGPGNIPPPP 461
Score = 34.3 bits (77), Expect = 0.73
Identities = 63/247 (25%), Positives = 78/247 (31%), Gaps = 59/247 (23%)
Query: 940 PQAPVAWERVAP---SNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFSNDP 996
P P +R P + LP PLP+S PP +P PP P
Sbjct: 224 PAGPPGVKRPPPPLMNGLPPRPPLPESLPPPPPGG--------------LPLPPMPPTGP 269
Query: 997 EPPAPALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSG 1056
P P PP QLP PG P PA + A G+ +
Sbjct: 270 APSGP--------PGPP--------QLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAP 313
Query: 1057 GGRSLIKKRLYVGEPHRGPGLPHGGTGRSLSSPNCFGPQPG----GPEMRRVNSAGRAPP 1112
G V P PG+ +G +P P PG P + P
Sbjct: 314 G----------VHPP--APGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPA 361
Query: 1113 GGLH-APRLSLEGAARG---AAEAKH-KAPGSADYGFAPAAGRSPYTTTRYGSPINTFTV 1167
G+H P + A G AA A H +APG PA G P + P
Sbjct: 362 PGVHPPPSAGVHPQAPGVHPAAPAVHPQAPGV----HPPAPGMHPQAPGVHPQPPGVHPS 417
Query: 1168 RPGTRHP 1174
PG HP
Sbjct: 418 APGV-HP 423
Score = 33.9 bits (76), Expect = 0.95
Identities = 27/74 (36%), Positives = 29/74 (39%), Gaps = 18/74 (24%)
Query: 398 PPAPPLPPPAPP------------LPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKP 445
PPAPP P PP LPP PPLP + PP G P P P P
Sbjct: 217 PPAPPSLPAGPPGVKRPPPPLMNGLPP-RPPLP--ESLPPPPPG--GLPLPPMPPTGPAP 271
Query: 446 N-PPSPENTASSAP 458
+ PP P AP
Sbjct: 272 SGPPGPPQLPPPAP 285
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 95.1 bits (235), Expect = 3e-19
Identities = 130/507 (25%), Positives = 191/507 (37%), Gaps = 90/507 (17%)
Query: 143 PPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPP---------PSMAPPPPPV 193
P GP P + PP LPS S P PPLL E PPP P PPPPP
Sbjct: 1419 PDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPP 1478
Query: 194 LEAL--SPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPA----------PAPPAPAS 241
AL PP +PS P PP +PP PP A +PPPPP PA PA P+P
Sbjct: 1479 QPALPSPPPLVAPTPSSPPPPP-LPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPED 1537
Query: 242 PHTVGTRLFPPGGVTKWKSDVALNGR-QAEATRASPPRSPAEPKGSALGPNPEPHLTFPR 300
P TR P + K + A+ G EA + E + P L
Sbjct: 1538 PELPDTR---PLHLAKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLAL 1594
Query: 301 SFKVPPPTPVRTSSIPVQ----EAQEAPRK---------EEGATKKAPSRLPLPPSFHIR 347
PP R +Q E ++ R+ G K RL + ++
Sbjct: 1595 QTGREPPPIWRVQKALLQKFTPEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVN 1654
Query: 348 PASQV-YPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPP 406
V R P P ++ + A + S A PPP P PPP P P
Sbjct: 1655 KKDYVRVCARKPWHRPPVPVRRSGQAKNPVSAGGSSA------PPPKAPAPPPKPETPEK 1708
Query: 407 APPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQ 466
+ PP +TP+++ P PP+PE + PV+ +
Sbjct: 1709 T--------------TSEKPP---EQTPETA------MPEPPAPEKPSLLRPVEKEKEKE 1745
Query: 467 M-----EKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGK---KGPRLPEKETLLSL 518
LR E A +R E + +P + P+++ K + P K+ L
Sbjct: 1746 KVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPPKKRKKWLKEA 1805
Query: 519 PAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIP-QDSPTPSVRQI-RNELEARLSS 576
T G P GSS +++E++P +P + T ++R++ R+ +E +S+
Sbjct: 1806 GGNATAGGGPP----GSS-SDSESSPGAPSEDERAVPGRLLKTRAMREMYRSYVEMLVST 1860
Query: 577 AAEKEAKPSIGS------LPPKPRLEG 597
A + + ++ LPP +++G
Sbjct: 1861 ALDPDMIQALEDTHDELYLPPMRKIDG 1887
Score = 89.4 bits (220), Expect = 2e-17
Identities = 237/1031 (22%), Positives = 345/1031 (33%), Gaps = 234/1031 (22%)
Query: 140 PPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSP 199
PPPPP A Q P G L + P PL+L PPPP + P + A SP
Sbjct: 764 PPPPPPTA----QSTQPTPHGLLLEA----GGPDLPLVLPPPPPQLL---PSVLSHAPSP 812
Query: 200 PHTLSSPSI----PTPPDFIPPAPPLAFLAPPPPPVPAP------------APPAPASPH 243
+ S + P D P PP PPPPP P P P AP+
Sbjct: 813 SPSASKVGVHLLEPATRDGAPQPPP----PPPPPPPPMPLQLEAHLRSHGLEPAAPSPRL 868
Query: 244 TVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPA-EPKGSALGPNPE--------- 293
L PPG + + + T PP S +P G+ P+P+
Sbjct: 869 RPEESLDPPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSPSPQGTKAPRFVP 928
Query: 294 -PHLTFP--------RSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSF 344
+ FP RSF P + + P ++EG K P PP++
Sbjct: 929 LTSICFPDSLLQDEERSF-FPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPPPGPPAY 987
Query: 345 HIRPASQVYPDRAP-----------EPDCPGELKATAPASPRLGQSQSQADERAGTPPPA 393
P P RA +P+ P EL +T A P LG QS +A PPP
Sbjct: 988 D--PYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEP-LGLIQS-GPHQAAPPPPP 1043
Query: 394 PPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPP----- 448
PP PPPA P + P P+ C+ K K K+SS L + +PP
Sbjct: 1044 PPPPPPA----PASEPKGGLTSPIFCSTKP-------KKLLKTSSFHLLRRRDPPFQTPK 1092
Query: 449 ---------SPENTASSAPVDWR-DPSQMEKLRNELAAYLCGSRRED-RFLSHRPGPTVA 497
+ + P D R +P ++ L + + S D F PGP
Sbjct: 1093 KLYAQEYEFEADEDKADVPADIRLNPRRLPDLVSSCRSRPALSPLGDIDFCPPNPGPD-G 1151
Query: 498 PQ------SKEGKKGPRLP---------EKETLLSLPAKDTPP-------------GVPE 529
P+ +K + GP P E T + TP G
Sbjct: 1152 PRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKA 1211
Query: 530 KSLGGS----------SLTETEAAPSLTLPSVDYIP-QDSPTPSVRQIRNELEARLSSAA 578
+ GG+ L+ +A L S D I D + R ++EA++
Sbjct: 1212 EEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVE 1271
Query: 579 EKEAKPSIGSLPP-KPRLEGGR----ICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQP 633
EK+ + G + L+ G+ + + G LS P K++PP +P LQP
Sbjct: 1272 EKQPEMKSGFMASFLDFLKSGKRHPPLYQAGL-TPPLSPP--KSVPPS----VPARGLQP 1324
Query: 634 KAMLGPAIPPKATPEPAIPPKATLWPATPPKATLGPATP-------LKATSGPTTPLKAT 686
+ PA+ P P A L A LG +P LK +
Sbjct: 1325 QPPATPAV-PHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSD 1383
Query: 687 SGPAIASTATTLPTTTSQLMAEKD---------SGPAGQPEKPASQEVSTP-----SQAR 732
++A + +S + A D S P G P PA+ P A
Sbjct: 1384 EEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSAN 1443
Query: 733 GEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVMPTLARG 792
G+P P + PP +P P P Q +L +V PT
Sbjct: 1444 SNGTPEP----PLLEEKPPPTPPPAPTPQPQPPP---PPPPPQPALPSPPPLVAPT---- 1492
Query: 793 GAAGPGEPVEVKEPPGLPAKP--------PASAQPTDELLRHPVTGEVVERGSPMALLLA 844
++ P P+ PP +P+ P P +A P + P E+ + P+ L
Sbjct: 1493 PSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDT-RPLHLAKK 1551
Query: 845 ARQRAQKGRSVGAALGRSSLPGSLRDHSHQAEASSD------SIFHSQGTPNSFTVVPKL 898
A G + A G S G R+ + D ++ + P + V L
Sbjct: 1552 QETAAVCGETDEEA-GESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKAL 1610
Query: 899 -------PKEAEKDSPLTTEIPNKWGPRLGR-------------DAEGTELSRRHNWTKP 938
K+ ++ T+ +G R + + R W +P
Sbjct: 1611 LQKFTPEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRVCARKPWHRP 1670
Query: 939 EPQAPVAWERVAPSNLP-----QGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPEFS 993
PV R + P P PK+ + PP P + E+ PPE +
Sbjct: 1671 ----PVPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEK--------PPEQT 1718
Query: 994 ND---PEPPAP 1001
+ PEPPAP
Sbjct: 1719 PETAMPEPPAP 1729
Score = 87.0 bits (214), Expect = 9e-17
Identities = 148/590 (25%), Positives = 206/590 (34%), Gaps = 73/590 (12%)
Query: 191 PPVLEA-LSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRL 249
PP+ +A L+PP + PP +PP+ P L P PP PA P P+ +G
Sbjct: 1296 PPLYQAGLTPPLS--------PPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGG-- 1345
Query: 250 FPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTP 309
AL ++E P SP + L N E T P SF
Sbjct: 1346 -------------ALEAAESEGLGLGCP-SPCKRLDEELKRNLE---TLP-SFSSDEEDS 1387
Query: 310 VRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKAT 369
V + + A + P P + PA+ V P P P P
Sbjct: 1388 VAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAV-PGPPPLPGLPSANSNG 1446
Query: 370 APASPRLGQSQSQADERAGTPPPAP-PLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPA 428
P P L + TPPPAP P P P PP PPP P L P+ PPL ++ PP
Sbjct: 1447 TPEPPLLEEKPPP------TPPPAPTPQPQPPPPPPPPQPAL-PSPPPLVAPTPSSPPPP 1499
Query: 429 GFTKTPKSSSPALKPKPNPPS------PENTASSAPVD--WRDPSQMEKLRNELAAYLCG 480
P + P+ P P P + PE A+ +P D D + + + A +CG
Sbjct: 1500 PLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHLAKKQETAAVCG 1559
Query: 481 SRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTET 540
E+ S G + + + +P + L + P +K+L E
Sbjct: 1560 ETDEEAGESGGEG-IFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEI 1618
Query: 541 EAAPSLTLPSVDYIPQ--DSPTPSVRQIRNELEARLSSAAEKEAKPSIGSLPPKP-RLEG 597
+ + +Y+ D+ R LE + PP P R G
Sbjct: 1619 KDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPVPVRRSG 1678
Query: 598 GRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATL 657
A P A PP+ T TTS +P P A PEP P K +L
Sbjct: 1679 QAKNPVSAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQ----TPETAMPEPPAPEKPSL 1734
Query: 658 W-----PATPPKATLG--PATPLKATSGPTTPLK---ATSGPAIASTATTLPTTTSQLMA 707
K T G P +ATSG T + AT PA + PT ++ A
Sbjct: 1735 LRPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPT---KVKA 1791
Query: 708 EKDSGPAGQPEKPASQEVSTPSQARG--EGSPSEATRLPTQGARSSAAFP 755
E P + K +E + A G GS S++ P + A P
Sbjct: 1792 E----PPPKKRKKWLKEAGGNATAGGGPPGSSSDSESSPGAPSEDERAVP 1837
Score = 68.2 bits (165), Expect = 5e-11
Identities = 248/1122 (22%), Positives = 364/1122 (32%), Gaps = 198/1122 (17%)
Query: 83 PLNAQENHGLAVPTPSVPDDFADKEVTGTSSLVNGNLRLY--SSVGDLRPGQYGQDLLIP 140
P A + GL +PS+ TG S ++G+ + SS+G G+ +I
Sbjct: 515 PGPAAHSQGLPTASPSLSYS------TGHSPALSGHGGGWGPSSLGG--GGEASPSHIIR 566
Query: 141 PPPPGPAPGPPQDISEP--PG---GSPLPSPPSTAPPPP-----------------PLLL 178
P PA G P + P PG S L S P APP LL
Sbjct: 567 PLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLA 626
Query: 179 EPPPPPSMAPPPPP-----VLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPA 233
P PP+ +L+A SPP T + + + L P
Sbjct: 627 GPGGPPAERTEDEEFLIQHLLQAPSPPRTSGADGLVGEDGAADASKGLGGSGGAGGPPGT 686
Query: 234 PAPPAPASPH------TVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSA 287
P A P + T G T + + L + + + P R P+G A
Sbjct: 687 PYELAKEDPQRYHLQSVIRTSASLDEGAT---AALELGLGRLKEKKKGPERGGETPEGLA 743
Query: 288 L-----GPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPP 342
G + F + PPP P S+ P E P LP PP
Sbjct: 744 TSVVHYGAGAKELGAFLQK-SPPPPPPTAQSTQPTPHGLLL----EAGGPDLPLVLPPPP 798
Query: 343 SFHIRPASQVYPD---RAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPP 399
Q+ P AP P +P++ ++G + R G P P PP PPP
Sbjct: 799 P-------QLLPSVLSHAPSP---------SPSASKVGVHLLEPATRDGAPQPPPPPPPP 842
Query: 400 APPLPPPAPP------LPPAAP-PLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPS--P 450
PP+P L PAAP P +++ PP + + P L P P P
Sbjct: 843 PPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELLGALEP-LPPAPGDTGVGP 901
Query: 451 ENTASSAPVD-WRDPSQM-----------------EKLRNELAAY------LCGSRREDR 486
N+ P +R PS L++E ++ + G D
Sbjct: 902 PNSEGKDPAGAYRSPSPQGTKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADD 961
Query: 487 FLSHRP-----------GPTVAPQSKE-------GKKGPRLPEKETLLSLPAKDTPPGVP 528
+ P GP P + + G+ PE L P K PP +P
Sbjct: 962 YGKAGPPEDEGDPKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNK--PPELP 1019
Query: 529 EKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQIRNELEARL--SSAAEKEAKPSI 586
++ L ++ P P P P P+ + + L + + S+ +K K S
Sbjct: 1020 S-TVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPA-SEPKGGLTSPIFCSTKPKKLLKTSS 1077
Query: 587 GSL-----PP--KPRLEGGRICENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGP 639
L PP P+ + E AD+DK P L P+ L +S + + L P
Sbjct: 1078 FHLLRRRDPPFQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLPDL-VSSCRSRPALSP 1136
Query: 640 AIPPKATPEPAIPPKATLWPATPPKATL-GPATPLKATSGPTTPLKATSGPAIASTATT- 697
P P P KA GP P + T+GPA AST T
Sbjct: 1137 LGDIDFCPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDG 1196
Query: 698 --LPTTTSQ---LMAEKDSGPAGQPEKPASQEVSTPSQARGEGSPS-EATRLPTQGARSS 751
P + AE+ G +P KP ++S P G G+ S +A + S
Sbjct: 1197 AKKPRGRGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKAGEGLGTSSGDAISGTDHNSLDS 1256
Query: 752 AAFPPKTSPGGGEVPCLYKPHCHQSSLSREVAVVM-----PTLARGGAAGPGEPVEVKEP 806
+ K EV +P ++ + + P L + G P P + P
Sbjct: 1257 SLTREKIEAKIKEVE-EKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPK-SVP 1314
Query: 807 PGLPAKPPASAQPTDELLRHPVTGEVVERGSPMALLLAARQRAQKGRSVGAALGRSS--- 863
P +PA+ P + HP G + + S G LG S
Sbjct: 1315 PSVPARGLQPQPPATPAVPHPPPSGAFGLGGAL----------EAAESEGLGLGCPSPCK 1364
Query: 864 -----LPGSLRDHSHQAEASSDSIFHSQGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGP 918
L +L + DS+ ++ S + + P T P+ GP
Sbjct: 1365 RLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPD--GP 1422
Query: 919 RLGRDAEGTE------LSRRHNWTKPEPQAPVAWERVAPSNLPQGHPLPKSFSSPPSPSN 972
L A L ++ PEP P+ E+ P+ P P P+ PP P
Sbjct: 1423 PLAPAAAVPGPPPLPGLPSANSNGTPEP--PLLEEKPPPTPPPAPTPQPQPPPPPPPPQP 1480
Query: 973 KREEEEEEFNFEVI---------PPPPEFSNDPEPPAPALQYLGRQSSPPRNNYSDLRQL 1023
PPPP + P PP PA L P + +L
Sbjct: 1481 ALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPEL 1540
Query: 1024 PNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGRSLIKKR 1065
P+ P L ++ A G E GG + ++R
Sbjct: 1541 PDTRP-----LHLAKKQETAAVCGETDEEAGESGGEGIFRER 1577
Score = 51.2 bits (121), Expect = 6e-06
Identities = 195/899 (21%), Positives = 281/899 (31%), Gaps = 176/899 (19%)
Query: 277 PRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPS 336
P S P SAL P R F VP SS+ +Q+ +P P+
Sbjct: 137 PGSSTFPSSSALSAYQHPASFGSRPFPVP-------SSLSLQDPPFSP----------PA 179
Query: 337 RLPLPPS--FHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAP 394
L P H++P+ +AP T P+S LG + G P
Sbjct: 180 NGLLSPHDVLHLKPS------QAP----------TVPSS--LGFERLAGGGVLGPAGLGP 221
Query: 395 PLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTA 454
PP P PP PP P H P F SS+ A + + P N +
Sbjct: 222 AQTPPYRPGPPDPPPPP------------RHLPTQFNLLASSSAAAAAAEQSSPQLYNFS 269
Query: 455 SSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKE------GKKGPR 508
+AP P + R + + R S +P P P G P
Sbjct: 270 GAAPGP--PPPERALPRQDTVI-----KHYQRPASAQPPPPPPPAHALQHYLSCGGSYPS 322
Query: 509 LPEKETLLSLP--AKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQI 566
+ + L P + PG E S G S A+ T P +
Sbjct: 323 MGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEA------AGGGGAGGG 376
Query: 567 RNELEARLSSAAEKEAKPSIGSL------PPKPRLEGGRICENGADDDKLSKPVAKNLPP 620
+ S K K G+ PP PR C++ L P A
Sbjct: 377 GGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQS------LGGPAAAYATG 430
Query: 621 QSTTL-----LPTTSLQPKAMLGPAIPPKATP--EPAIPPKATLWPATPPKATLGPATPL 673
+++ + QP+ +LGP + + KA + PP+ GP P
Sbjct: 431 KASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPG 490
Query: 674 KATSGPTTP---------LKATSGPAIASTATTLPTTTSQLMAEKDSGPA----GQPEKP 720
AT +P ++ P A+ + LPT + L PA G P
Sbjct: 491 LATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYSTGHSPALSGHGGGWGP 550
Query: 721 ASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSR 780
+S GE SPS R P Q ++ P SPG P + SS+
Sbjct: 551 SSLG------GGGEASPSHIIR-PLQSPPATGRPPGVGSPGA--------PGKYLSSVLA 595
Query: 781 EVAVVMPTLA------RGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVTGEVVE 834
+ P A GG G G+ E+ PG P P + + L++H +
Sbjct: 596 SAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGP--PAERTEDEEFLIQHLLQAPSPP 653
Query: 835 RGSPMALLLAARQRAQKGRSVGAALGRSSLPGS---------LRDHSHQAEASSDSIFHS 885
R S L+ A + +G + G PG+ R H +S S+
Sbjct: 654 RTSGADGLVGEDGAADASKGLGGSGGAGGPPGTPYELAKEDPQRYHLQSVIRTSASL--D 711
Query: 886 QGTPNSFTVVPKLPKEAEKDSPLTTEIPNKWGPRLGRDAEGTELSRRHNWTKPEPQAPVA 945
+G + + KE +K E P + G + P P P A
Sbjct: 712 EGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTA 771
Query: 946 WERVAPSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIPPPPE------FSNDPEPP 999
S P H L P P V+PPPP S+ P P
Sbjct: 772 -----QSTQPTPHGLLLEAGGPDLPL-------------VLPPPPPQLLPSVLSHAPSP- 812
Query: 1000 APALQYLGRQSSPPRNNYSDLRQLPNAGPGAPPALGFSRFPAGARYAGAGGLERFSGGGR 1059
+P+ +G P Q P P PP + + + GLE + R
Sbjct: 813 SPSASKVGVHLLEPATR-DGAPQPPPPPPPPPPPMPLQL----EAHLRSHGLEPAAPSPR 867
Query: 1060 SLIKKRLYVGEPHRGPGLPHGGTGRSLSSPNCFGPQPGGPEMRRVNSAGRAPPGGLHAP 1118
++ L P G L + P PG + NS G+ P G +P
Sbjct: 868 LRPEESLD----------PPGAMQELLGALEPLPPAPGDTGVGPPNSEGKDPAGAYRSP 916
Score = 50.8 bits (120), Expect = 7e-06
Identities = 186/826 (22%), Positives = 262/826 (31%), Gaps = 149/826 (18%)
Query: 97 PSVPDDFADKEVTGTSSLVNGNLRLYSSVGDLRPGQYGQDLLIPPPPPGPAP-------- 148
P+VP G L G + + +G + Y PPPPP P
Sbjct: 197 PTVPSSL------GFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLAS 250
Query: 149 ----GPPQDISEPP-----GGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSP 199
+ S P G +P P PP A P +++ P+ A PPPP A +
Sbjct: 251 SSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHAL 310
Query: 200 PHTLSS----PSIPTPPDFIPPAPPLAFLAPPP-PPVPAPAPPAPASPHTVGTRLFPP-- 252
H LS PS+ + PL P P P+ A P+ A+ G P
Sbjct: 311 QHYLSCGGSYPSMGHRANL--ACSPLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAA 368
Query: 253 ------GGVTKWKSDVALNGRQ----------AEATRASPPRSPAEPKGSALGPNPEPHL 296
GG ++ + G + ATR PPRS A PK +LG +
Sbjct: 369 GGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAGGATRPPPPRSTATPKCQSLGGPAAAYA 428
Query: 297 TFPRS------FKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPAS 350
T S + P + P Q + KAPS PP
Sbjct: 429 TGKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQ------- 481
Query: 351 QVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPL 410
P P P PG L SP Q Q Q G P P P P P+
Sbjct: 482 ---PPSGPPP--PG-LATCQSYSP--DQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSY 533
Query: 411 PPAAPPLPCAQKAAHPPAGFTKTPKSS-SPALKPKPNPPSPENTASSAPVDWRDPSQMEK 469
P P+ ++S S ++P +PP A+ P P K
Sbjct: 534 STGHSPALSGHGGGWGPSSLGGGGEASPSHIIRPLQSPP-----ATGRPPGVGSPGAPGK 588
Query: 470 LRNELAA------------YLCGS-----RREDRFLSHRPGPTVAPQSKEGK-------K 505
+ + A Y G+ + + L PG A ++++ + +
Sbjct: 589 YLSSVLASAPFLAPPGAGSYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQ 648
Query: 506 GPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAAPSLTLPSVDYIPQDSPTPSVRQ 565
P P L +D K LGGS L D PQ SV +
Sbjct: 649 APSPPRTSGADGLVGEDGAADA-SKGLGGSGGAGGPPGTPYELAKED--PQRYHLQSVIR 705
Query: 566 IRNELEARLSSAAE------KEAKPSIGSLPPKPRLEGGRICENGADDDKLSKPVAKNLP 619
L+ ++A E KE K P + GA +L + K+ P
Sbjct: 706 TSASLDEGATAALELGLGRLKEKKKGPERGGETPEGLATSVVHYGAGAKELGAFLQKSPP 765
Query: 620 PQSTTLLPTTSLQPKAML----GPAIPPKATPEP--AIPPKATLWPATPPKAT------L 667
P T +T P +L GP +P P P +P + P+ P A+ L
Sbjct: 766 PPPPT-AQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLL 824
Query: 668 GPAT------PLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAG------ 715
PAT P P P+ + S + +L E+ P G
Sbjct: 825 EPATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPGAMQELL 884
Query: 716 ---QPEKPASQEVST-PSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKP 771
+P PA + P + G+ P+ A R P+ + F P TS + P
Sbjct: 885 GALEPLPPAPGDTGVGPPNSEGK-DPAGAYRSPSPQGTKAPRFVPLTS--------ICFP 935
Query: 772 HCHQSSLSREVAVVMPTLARGGAA---GPGEPVEVKEPPGLPAKPP 814
R M + GGAA G P E + P A PP
Sbjct: 936 DSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGPP 981
Score = 47.4 bits (111), Expect = 8e-05
Identities = 73/313 (23%), Positives = 98/313 (31%), Gaps = 40/313 (12%)
Query: 110 GTSSLVNGNLRLYSSVGDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPST 169
G S L + L S G P +L+ GP PGP SP
Sbjct: 67 GLSGLFDTGLHHAGSAG---PDASVMNLISALESRGPQPGPSASSLLSQFRSPSWQTAMH 123
Query: 170 APPPPPLLLEPPPPPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFI----PPAPPLAFLA 225
P P L + P S P L A P + S P P P +PP L
Sbjct: 124 TPGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPFPVPSSLSLQDPPFSPPANGLL 183
Query: 226 PPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKG 285
P + AP P ++G GGV L Q R PP P P+
Sbjct: 184 SPHDVLHLKPSQAPTVPSSLGFERLAGGGVL---GPAGLGPAQTPPYRPGPPDPPPPPR- 239
Query: 286 SALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPP--- 342
HL P F + + +SS A+++ + + AP P PP
Sbjct: 240 ---------HL--PTQFNL-----LASSSAAAAAAEQSSPQLYNFSGAAPG--PPPPERA 281
Query: 343 --------SFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAP 394
+ RPAS P P + + P +G + A G P+P
Sbjct: 282 LPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGSYPSMGHRANLACSPLGGGEPSP 341
Query: 395 PLPPPAPPLPPPA 407
P+ P A
Sbjct: 342 GAGEPSKAGPSGA 354
Score = 42.4 bits (98), Expect = 0.003
Identities = 66/239 (27%), Positives = 84/239 (35%), Gaps = 44/239 (18%)
Query: 950 APSNLPQGHPLPKSFSSPPSPSNKREEEEEEFNFEVIP----PPPEFSNDPEPPAPALQ- 1004
A + PQ + + PP P ++ P PPP P PPA ALQ
Sbjct: 258 AEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPP-----PPPPAHALQH 312
Query: 1005 YLGRQSSPPRNNYSDLRQL-------PNAGPGAPPALGFSRFPAGA-------RYAGAGG 1050
YL S P + P+ G G P G S AGA AG GG
Sbjct: 313 YLSCGGSYPSMGHRANLACSPLGGGEPSPGAGEPSKAGPSGATAGASGRATGPEAAGGGG 372
Query: 1051 LERFSGGGRSLIKKRLYVGEPHRGPGLPHGGTGR-----SLSSPNCFGPQPGGPEMR--- 1102
GG R +I+ Y G G GG R S ++P C GGP
Sbjct: 373 AGGGGGGYRPIIQSPGYK-TGKGGYGAAAGGATRPPPPRSTATPKC--QSLGGPAAAYAT 429
Query: 1103 -RVNSAGRA--------PPGGLHAPRLSLEGAARGAAEAKHKAPGSADYGFAPAAGRSP 1152
+ + AG A P GL P+ +G G A+ KAP + P +G P
Sbjct: 430 GKASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPP 488
Score = 34.7 bits (78), Expect = 0.56
Identities = 44/157 (28%), Positives = 52/157 (33%), Gaps = 28/157 (17%)
Query: 141 PPPPGPAPGP-PQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLE---- 195
PPP PAP P P+ + P P TA P PP P PS+ P E
Sbjct: 1692 PPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPP----APEKPSLLRPVEKEKEKEKV 1747
Query: 196 -----------ALSPPHTLSSPSIPT---PPDFIPPAPPLAFLAPPPPPVPAPAPPAPAS 241
A S T S+ T +P A P A PPP
Sbjct: 1748 TRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPPKKRKKWLKEAGG 1807
Query: 242 PHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPR 278
T G PPG + +S G +E RA P R
Sbjct: 1808 NATAGGG--PPGSSSDSESS---PGAPSEDERAVPGR 1839
Score = 33.9 bits (76), Expect = 0.95
Identities = 43/194 (22%), Positives = 57/194 (29%), Gaps = 52/194 (26%)
Query: 141 PPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPPPPPVLEALSPP 200
PP P G ++ G S +PP AP PPP +P P PP
Sbjct: 1670 PPVPVRRSGQAKNPVSAGGSS---APPPKAPAPPP---KPETPEKTTSEKPP-------- 1715
Query: 201 HTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKS 260
P P PPAP P L P K K
Sbjct: 1716 -------------------------EQTPETAMPEPPAPEKP-----SLLRPVEKEKEKE 1745
Query: 261 DVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEA 320
V R RA+ R + A G P + ++P P + + P +
Sbjct: 1746 KVTRGERPLRGERATSGRQTRPERSLATGQ--------PATSRLPKARPTKVKAEPPPKK 1797
Query: 321 QEAPRKEEGATKKA 334
++ KE G A
Sbjct: 1798 RKKWLKEAGGNATA 1811
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.131 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,186,076
Number of Sequences: 37866
Number of extensions: 6108069
Number of successful extensions: 166565
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1439
Number of HSP's successfully gapped in prelim test: 2338
Number of HSP's that attempted gapping in prelim test: 31781
Number of HSP's gapped (non-prelim): 48390
length of query: 1188
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1075
effective length of database: 13,968,660
effective search space: 15016309500
effective search space used: 15016309500
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.