Guide to the Human Genome
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Search of human proteins with 239753963

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239753963 PREDICTED: similar to apopolysialoglycoprotein
[Homo sapiens]
         (538 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239753963 PREDICTED: similar to apopolysialoglycoprotein [Hom...  1057   0.0  
gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo sap...    98   2e-20
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             82   9e-16
gi|239757530 PREDICTED: hypothetical protein [Homo sapiens]            75   2e-13
gi|239752052 PREDICTED: hypothetical protein [Homo sapiens]            75   2e-13
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   61   2e-09
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   61   2e-09
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   61   2e-09
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    61   2e-09
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        61   2e-09
gi|60097902 filaggrin [Homo sapiens]                                   59   9e-09
gi|78042577 MAP7 domain containing 1 [Homo sapiens]                    56   7e-08
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]        55   1e-07
gi|148746195 trichohyalin [Homo sapiens]                               55   2e-07
gi|41322923 plectin 1 isoform 11 [Homo sapiens]                        55   2e-07
gi|41322914 plectin 1 isoform 10 [Homo sapiens]                        55   2e-07
gi|41322919 plectin 1 isoform 8 [Homo sapiens]                         55   2e-07
gi|41322910 plectin 1 isoform 7 [Homo sapiens]                         55   2e-07
gi|41322916 plectin 1 isoform 6 [Homo sapiens]                         55   2e-07
gi|41322908 plectin 1 isoform 3 [Homo sapiens]                         55   2e-07
gi|41322912 plectin 1 isoform 2 [Homo sapiens]                         55   2e-07
gi|47607492 plectin 1 isoform 1 [Homo sapiens]                         55   2e-07
gi|24308215 retrotransposon gag domain containing 1 [Homo sapiens]     52   1e-06
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]              52   1e-06
gi|102467235 inner centromere protein antigens 135/155kDa isofor...    46   8e-05
gi|21450645 tetratricopeptide repeat domain 16 [Homo sapiens]          46   8e-05
gi|239754474 PREDICTED: similar to mucin [Homo sapiens]                46   1e-04
gi|210032580 SET domain containing 1B [Homo sapiens]                   46   1e-04
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         46   1e-04
gi|102467242 inner centromere protein antigens 135/155kDa isofor...    45   2e-04

>gi|239753963 PREDICTED: similar to apopolysialoglycoprotein [Homo
           sapiens]
          Length = 538

 Score = 1057 bits (2733), Expect = 0.0
 Identities = 538/538 (100%), Positives = 538/538 (100%)

Query: 1   MSEAVQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRR 60
           MSEAVQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRR
Sbjct: 1   MSEAVQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRR 60

Query: 61  HPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSE 120
           HPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSE
Sbjct: 61  HPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSE 120

Query: 121 AAQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAVQRRDPADTMSEAVQRRHPA 180
           AAQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAVQRRDPADTMSEAVQRRHPA
Sbjct: 121 AAQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAVQRRDPADTMSEAVQRRHPA 180

Query: 181 DTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQ 240
           DTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQ
Sbjct: 181 DTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQ 240

Query: 241 RRHPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTM 300
           RRHPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTM
Sbjct: 241 RRHPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTM 300

Query: 301 SEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAVQRRH 360
           SEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAVQRRH
Sbjct: 301 SEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAVQRRH 360

Query: 361 PADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEA 420
           PADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEA
Sbjct: 361 PADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEA 420

Query: 421 AQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEAVQRRHPAD 480
           AQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEAVQRRHPAD
Sbjct: 421 AQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEAVQRRHPAD 480

Query: 481 PMSEAAQRRDLADTMSEAAQRRDPEDTMSEAAQRRDPADAMSEAAQRRDPEDTMSEVA 538
           PMSEAAQRRDLADTMSEAAQRRDPEDTMSEAAQRRDPADAMSEAAQRRDPEDTMSEVA
Sbjct: 481 PMSEAAQRRDLADTMSEAAQRRDPEDTMSEAAQRRDPADAMSEAAQRRDPEDTMSEVA 538


>gi|88501738 TRIO and F-actin binding protein isoform 6 [Homo
           sapiens]
          Length = 2365

 Score = 98.2 bits (243), Expect = 2e-20
 Identities = 116/531 (21%), Positives = 217/531 (40%), Gaps = 49/531 (9%)

Query: 23  PADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRRHPADTMSEAAQRRHPADTMSEA 82
           P  T S+A+  +   DT   A+ R  P  ++   + +R  +   S   +    + T  E 
Sbjct: 252 PRSTTSQASPAQR--DTAQAASTREIPRASSPHRITQRDTSRASSTQQEISRASSTQQET 309

Query: 83  VQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHP--ADTMSEAAQRRHP 140
            +     +    A+  +      S        A + S + Q  +P  + T  +  Q   P
Sbjct: 310 SRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQQDNPQTSFP 369

Query: 141 ADTMSEAVQRRHPADTMSEAVQRRDP-ADTMSEAVQRRHPADTMSEAAQRRHPADTMSEA 199
             T     QR +P    +  VQ+ DP A + +   QR +   + +  AQR +P  + + +
Sbjct: 370 TCTP----QRENPR---TPCVQQDDPRASSPNRTTQREN---SRTSCAQRDNPKASRTSS 419

Query: 200 AQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPAD 259
             R    +  +  AQR +P  +    A R +P    +  AQR +P  + + +  R    +
Sbjct: 420 PNRATRDNPRTSCAQRDNPRASSPSRATRDNPT---TSCAQRDNPRASRTSSPNRATRDN 476

Query: 260 TISEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQR 319
             +  AQR +P  +    A R +P    +  AQR +P  + + +  R    +  +  AQR
Sbjct: 477 PRTSCAQRDNPRASSPSRATRDNPT---TSCAQRDNPRASRTSSPNRATRDNPRTSCAQR 533

Query: 320 RDPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAVQRRHPADTMSEAAQRRDPADTMS 379
            +P  +    A R +P    +   QR +P  + + +  R    +  +  AQR +P  +  
Sbjct: 534 DNPRASSPNRAARDNPT---TSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSP 590

Query: 380 EAAQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAAQRRDP 439
             A R +P    +  AQR +P  + + +  R    +  +  AQR +P  +      ++D 
Sbjct: 591 NRATRDNPT---TSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDS 647

Query: 440 ADTMSEAAQRRDP-ADTMSEAAQRRHP-----------ADTTSEAVQRRHPADPMSEAAQ 487
             T    A+R DP A + +   Q+ +P           A + S  +Q+    +P +  AQ
Sbjct: 648 PRT--SCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQE---NPRTSCAQ 702

Query: 488 RRD-LADTMSEAAQRRDPEDTMSEAAQRRDP-ADAMSEAAQRRDPEDTMSE 536
           R D  A + +   Q+ +P    +  A+R +P A + +   QR +P  + ++
Sbjct: 703 RDDPRASSPNRTTQQENPR---TSCARRDNPRASSRNRTIQRDNPRTSCAQ 750



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 65/336 (19%), Positives = 129/336 (38%), Gaps = 15/336 (4%)

Query: 201 QRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADT 260
           + R      S       P  T S+A+  +   DT   A+ R  P  +      +RD +  
Sbjct: 235 RHRSTLTQASSMTPHSGPRSTTSQASPAQ--RDTAQAASTREIPRASSPHRITQRDTSRA 292

Query: 261 ISEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRR 320
            S   +    + T  E ++     +    A+  ++     S        A + S + Q  
Sbjct: 293 SSTQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLD 352

Query: 321 DPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAVQRRHPADTMSEAAQRRDPADTMSE 380
           +P    + + Q+ +P  +      +R    T    VQ+  P  +      +R+ + T   
Sbjct: 353 NPR---TSSTQQDNPQTSFPTCTPQRENPRT--PCVQQDDPRASSPNRTTQRENSRT--S 405

Query: 381 AAQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAAQRRDPA 440
            AQR +P  + + +  R    +  +  AQR +P  +    A R +P    +  AQR +P 
Sbjct: 406 CAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPT---TSCAQRDNPR 462

Query: 441 DTMSEAAQRRDPADTMSEAAQRRHPADTTSEAVQRRHPADPMSEAAQRRDLADTMSEAAQ 500
            + + +  R    +  +  AQR +P  ++     R +P    +  AQR +   + + +  
Sbjct: 463 ASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPT---TSCAQRDNPRASRTSSPN 519

Query: 501 RRDPEDTMSEAAQRRDPADAMSEAAQRRDPEDTMSE 536
           R   ++  +  AQR +P  +    A R +P  + ++
Sbjct: 520 RATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQ 555


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 82.4 bits (202), Expect = 9e-16
 Identities = 92/334 (27%), Positives = 130/334 (38%), Gaps = 6/334 (1%)

Query: 205  PADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTISEA 264
            P   ++ A     P +  + A +   P +  S AA    P +  S AA    P +  S A
Sbjct: 971  PEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1030

Query: 265  AQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPAD 324
            A    P +  S AA    P +  S AA    P +  S AA    P +  S AA    P +
Sbjct: 1031 AAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1090

Query: 325  TMSEAAQRRDPADTMSEAVQRRHPADTMSEAVQRRHPADTMSEAAQRRDPADTMSEAAQR 384
              S AA    P +  S A     P +  S A     P +  S AA    P +    A   
Sbjct: 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV 1150

Query: 385  RHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMS 444
              P ++ S A     P ++ S AA    PA++ S AA      +  S AA    PA  ++
Sbjct: 1151 PTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVA 1210

Query: 445  EAAQRRDPADTMSEAAQRRHPADTTSEAVQRRHPADPMSEAAQRRDLADTMSEAAQRRDP 504
               +   PA ++  + +   PA   S A    +P +P S AA    L +  S AA    P
Sbjct: 1211 TLEEFTSPAASVPTSEE---PA---SLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTP 1264

Query: 505  EDTMSEAAQRRDPADAMSEAAQRRDPEDTMSEVA 538
            E+  S AA    P +  S AA   + E+  S  A
Sbjct: 1265 EELSSPAASVPTPEEPASPAAAVSNLEEPASPAA 1298



 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 99/365 (27%), Positives = 138/365 (37%), Gaps = 19/365 (5%)

Query: 153  PADTMSEAVQRRDPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEA 212
            P   ++ A     P +  + AV+   P +  S AA    P +  S AA    P +  S A
Sbjct: 971  PEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1030

Query: 213  AQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTISEAAQRRDPAD 272
            A    P +  S AA    P +  S AA    P +  S AA    P +  S AA    P +
Sbjct: 1031 AAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1090

Query: 273  TMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQR 332
              S AA    P +  S AA    P +  S AA    P +  S AA    P +    A   
Sbjct: 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV 1150

Query: 333  RDPADTMSEAVQRRHPADTMSEAVQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMS 392
              P ++ S AV    P ++ S A     PA++ S AA      +  S AA    PA  ++
Sbjct: 1151 PTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVA 1210

Query: 393  EAAQRRDPADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDP 452
               +   PA ++  + +   PA                S AA   +P +  S AA     
Sbjct: 1211 TLEEFTSPAASVPTSEE---PA----------------SLAAAVSNPEEPTSPAAAVPTL 1251

Query: 453  ADTMSEAAQRRHPADTTSEAVQRRHPADPMSEAAQRRDLADTMSEAAQRRDPEDTMSEAA 512
             +  S AA    P + +S A     P +P S AA   +L +  S AA    PE     AA
Sbjct: 1252 EEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAA 1311

Query: 513  QRRDP 517
                P
Sbjct: 1312 SVPTP 1316



 Score = 79.3 bits (194), Expect = 8e-15
 Identities = 93/340 (27%), Positives = 131/340 (38%), Gaps = 6/340 (1%)

Query: 192  PADTMSEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEA 251
            P   ++ A     P +  + A +   P +  S AA    P +  S AA    P +  S A
Sbjct: 971  PEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1030

Query: 252  AQRRDPADTISEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPAD 311
            A    P +  S AA    P +  S AA    P +  S AA    P +  S AA    P +
Sbjct: 1031 AAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1090

Query: 312  TMSEAAQRRDPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAVQRRHPADTMSEAAQR 371
              S AA    P +  S AA    P +  S A     P +  S A     P +    A   
Sbjct: 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV 1150

Query: 372  RDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRHPADTMS 431
              P ++ S A     P ++ S AA    PA++ S AA      +  S AA    PA  ++
Sbjct: 1151 PTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVA 1210

Query: 432  EAAQRRDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEAVQRRHPADPMSEAAQRRDL 491
               +   PA ++  +    +PA   S AA   +P + TS A       +P S AA     
Sbjct: 1211 TLEEFTSPAASVPTS---EEPA---SLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTP 1264

Query: 492  ADTMSEAAQRRDPEDTMSEAAQRRDPADAMSEAAQRRDPE 531
             +  S AA    PE+  S AA   +  +  S AA    PE
Sbjct: 1265 EELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPE 1304



 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 94/354 (26%), Positives = 129/354 (36%), Gaps = 7/354 (1%)

Query: 140  PADTMSEAVQRRHPADTMSEAVQRRDPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEA 199
            P   ++ A     P +  + AV+   P +  S A     P +  S AA    P +  S A
Sbjct: 971  PEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1030

Query: 200  AQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPAD 259
            A    P +  S AA    P +  S AA    P +  S AA    P +  S AA    P +
Sbjct: 1031 AAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1090

Query: 260  TISEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQR 319
              S AA    P +  S AA    P +  S AA    P +  S AA    P +    A   
Sbjct: 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV 1150

Query: 320  RDPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAVQRRHPADTMSEAAQRRDPADTMS 379
              P ++ S A     P ++ S A     PA++ S A       +  S AA    PA  ++
Sbjct: 1151 PTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVA 1210

Query: 380  EAAQRRHPA-------DTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRHPADTMSE 432
               +   PA       +  S AA   +P +  S AA      +  S AA    P +  S 
Sbjct: 1211 TLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSP 1270

Query: 433  AAQRRDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEAVQRRHPADPMSEAA 486
            AA    P +  S AA   +  +  S AA    P      A     P  P   AA
Sbjct: 1271 AASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPAA 1324



 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 89/334 (26%), Positives = 126/334 (37%), Gaps = 6/334 (1%)

Query: 88   PADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAAQRRHPADTMSEA 147
            P   ++ A     P +  + AV+   P +  S AA    P +  S AA    P +  S A
Sbjct: 971  PEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1030

Query: 148  VQRRHPADTMSEAVQRRDPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAAQRRDPAD 207
                 P +  S A     P +  S A     P +  S AA    P +  S AA    P +
Sbjct: 1031 AAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1090

Query: 208  TMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTISEAAQR 267
              S AA    P +  S AA    P +  S AA    P +  S AA    P +    A   
Sbjct: 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV 1150

Query: 268  RDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMS 327
              P ++ S A     P ++ S AA    PA++ S AA      +  S AA    PA  ++
Sbjct: 1151 PTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVA 1210

Query: 328  EAAQRRDPADTMSEAVQRRHPADTMSEAVQRRHPADTMSEAAQRRDPADTMSEAAQRRHP 387
               +   PA ++  +     PA   S A    +P +  S AA      +  S AA    P
Sbjct: 1211 TLEEFTSPAASVPTS---EEPA---SLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTP 1264

Query: 388  ADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAA 421
             +  S AA    P +  S AA   +  +  S AA
Sbjct: 1265 EELSSPAASVPTPEEPASPAAAVSNLEEPASPAA 1298



 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 93/352 (26%), Positives = 130/352 (36%), Gaps = 6/352 (1%)

Query: 101  PADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEA 160
            P   ++ A     P +  + A +   P +  S AA    P +  S A     P +  S A
Sbjct: 971  PEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1030

Query: 161  VQRRDPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPAD 220
                 P +  S A     P +  S AA    P +  S AA    P +  S AA    P +
Sbjct: 1031 AAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1090

Query: 221  TISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQR 280
              S AA    P +  S AA    P +  S AA    P +  S AA    P +    A   
Sbjct: 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV 1150

Query: 281  RDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMS 340
              P ++ S A     P ++ S AA    PA++ S AA      +  S AA    PA  ++
Sbjct: 1151 PTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVA 1210

Query: 341  EAVQRRHPADTMSEAVQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDP 400
               +   PA ++  +     PA   S AA   +P +  S AA      +  S AA    P
Sbjct: 1211 TLEEFTSPAASVPTS---EEPA---SLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTP 1264

Query: 401  ADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDP 452
             +  S AA    P +  S AA   +  +  S AA    P      AA    P
Sbjct: 1265 EELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTP 1316



 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 91/332 (27%), Positives = 125/332 (37%), Gaps = 6/332 (1%)

Query: 4    AVQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRRHPA 63
            AV+   P +  S A     P +  S AA    P + TS AA    P + TS       P 
Sbjct: 991  AVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPE 1050

Query: 64   DTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQ 123
            +  S AA    P +  S A     P +  S AA    P +  S A     P +  S AA 
Sbjct: 1051 EPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA 1110

Query: 124  RRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAVQRRDPADTMSEAVQRRHPADTM 183
               P +  S AA    P +  S A     P +    A     P ++ S AV    P ++ 
Sbjct: 1111 VPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESA 1170

Query: 184  SEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRH 243
            S AA    PA++ S AA      +  S AA    PA  ++   +   PA ++  + +   
Sbjct: 1171 SPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEE--- 1227

Query: 244  PADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEA 303
            PA   S AA   +P +  S AA      +  S AA    P +  S AA    P +  S A
Sbjct: 1228 PA---SLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPA 1284

Query: 304  AQRRHPADTMSEAAQRRDPADTMSEAAQRRDP 335
            A   +  +  S AA    P      AA    P
Sbjct: 1285 AAVSNLEEPASPAAAVPTPEVAAIPAASVPTP 1316



 Score = 70.5 bits (171), Expect = 4e-12
 Identities = 76/314 (24%), Positives = 116/314 (36%)

Query: 10   PADTMSEAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRRHPADTMSEA 69
            P +  + AV+   P +  S AA    P + TS AA    P + TS       P +  S A
Sbjct: 984  PEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPA 1043

Query: 70   AQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPAD 129
            A    P +  S A     P +  S AA    P +  S A     P +  S AA    P +
Sbjct: 1044 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1103

Query: 130  TMSEAAQRRHPADTMSEAVQRRHPADTMSEAVQRRDPADTMSEAVQRRHPADTMSEAAQR 189
              S AA    P +  S A     P +  S A     P +    A     P ++ S A   
Sbjct: 1104 PTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAV 1163

Query: 190  RHPADTMSEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMS 249
              P ++ S AA    PA++ S AA      +  S AA    PA  ++   +   PA ++ 
Sbjct: 1164 PTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVP 1223

Query: 250  EAAQRRDPADTISEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHP 309
             + +    A  +S   +   PA  +    +    A  +    +   PA ++    +   P
Sbjct: 1224 TSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASP 1283

Query: 310  ADTMSEAAQRRDPA 323
            A  +S   +   PA
Sbjct: 1284 AAAVSNLEEPASPA 1297



 Score = 69.3 bits (168), Expect = 8e-12
 Identities = 78/327 (23%), Positives = 120/327 (36%)

Query: 62   PADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEA 121
            P   ++ A     P +  + AV+   P +  S AA    P +  S A     P +  S A
Sbjct: 971  PEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1030

Query: 122  AQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAVQRRDPADTMSEAVQRRHPAD 181
            A    P +  S AA    P +  S A     P +  S A     P +  S A     P +
Sbjct: 1031 AAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1090

Query: 182  TMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQR 241
              S AA    P +  S AA    P +  S AA    P +  S AA    P +    A   
Sbjct: 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV 1150

Query: 242  RHPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMS 301
              P ++ S A     P ++ S AA    PA++ S AA      +  S AA    PA  ++
Sbjct: 1151 PTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVA 1210

Query: 302  EAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAVQRRHP 361
               +   PA ++  + +    A  +S   +   PA  +    +    A  +    +   P
Sbjct: 1211 TLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSP 1270

Query: 362  ADTMSEAAQRRDPADTMSEAAQRRHPA 388
            A ++    +   PA  +S   +   PA
Sbjct: 1271 AASVPTPEEPASPAAAVSNLEEPASPA 1297



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 77/327 (23%), Positives = 119/327 (36%)

Query: 75   PADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEA 134
            P   ++ A     P +  + A +   P +  S A     P +  S AA    P +  S A
Sbjct: 971  PEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1030

Query: 135  AQRRHPADTMSEAVQRRHPADTMSEAVQRRDPADTMSEAVQRRHPADTMSEAAQRRHPAD 194
            A    P +  S A     P +  S A     P +  S A     P +  S AA    P +
Sbjct: 1031 AAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1090

Query: 195  TMSEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQR 254
              S AA    P +  S AA    P +  S AA    P +  S AA    P +    A   
Sbjct: 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV 1150

Query: 255  RDPADTISEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMS 314
              P ++ S A     P ++ S AA    PA++ S AA      +  S AA    PA  ++
Sbjct: 1151 PTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVA 1210

Query: 315  EAAQRRDPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAVQRRHPADTMSEAAQRRDP 374
               +   PA ++  + +    A  +S   +   PA  +    +    A  +    +   P
Sbjct: 1211 TLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSP 1270

Query: 375  ADTMSEAAQRRHPADTMSEAAQRRDPA 401
            A ++    +   PA  +S   +   PA
Sbjct: 1271 AASVPTPEEPASPAAAVSNLEEPASPA 1297



 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 84/328 (25%), Positives = 120/328 (36%), Gaps = 7/328 (2%)

Query: 10   PADTMSEAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRRHPADTMSEA 69
            P   ++ A     P +  + A +   P +  S AA    P + TS       P +  S A
Sbjct: 971  PEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1030

Query: 70   AQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPAD 129
            A    P +  S A     P +  S AA    P +  S A     P +  S AA    P +
Sbjct: 1031 AAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1090

Query: 130  TMSEAAQRRHPADTMSEAVQRRHPADTMSEAVQRRDPADTMSEAVQRRHPADTMSEAAQR 189
              S AA    P +  S A     P +  S A     P +  S A     P +    A   
Sbjct: 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV 1150

Query: 190  RHPADTMSEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMS 249
              P ++ S A     P ++ S AA    PA++ S AA      +  S AA    PA  ++
Sbjct: 1151 PTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVA 1210

Query: 250  EAAQRRDPADTI-------SEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSE 302
               +   PA ++       S AA   +P +  S AA      +  S AA    P +  S 
Sbjct: 1211 TLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSP 1270

Query: 303  AAQRRHPADTMSEAAQRRDPADTMSEAA 330
            AA    P +  S AA   +  +  S AA
Sbjct: 1271 AASVPTPEEPASPAAAVSNLEEPASPAA 1298



 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 76/327 (23%), Positives = 117/327 (35%)

Query: 36   PADTTSEAAQRRHPADTTSEPVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEA 95
            P    + A     P +  +  V+   P +  S AA    P +  S A     P +  S A
Sbjct: 971  PEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1030

Query: 96   AQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAVQRRHPAD 155
            A    P +  S A     P +  S AA    P +  S AA    P +  S A     P +
Sbjct: 1031 AAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1090

Query: 156  TMSEAVQRRDPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQR 215
              S A     P +  S A     P +  S AA    P +  S AA    P +    A   
Sbjct: 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV 1150

Query: 216  RDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTISEAAQRRDPADTMS 275
              P ++ S A     P ++ S AA    PA++ S AA      +  S AA    PA  ++
Sbjct: 1151 PTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVA 1210

Query: 276  EAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDP 335
               +   PA ++  + +    A  +S   +   PA  +    +    A  +    +   P
Sbjct: 1211 TLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSP 1270

Query: 336  ADTMSEAVQRRHPADTMSEAVQRRHPA 362
            A ++    +   PA  +S   +   PA
Sbjct: 1271 AASVPTPEEPASPAAAVSNLEEPASPA 1297



 Score = 65.9 bits (159), Expect = 9e-11
 Identities = 77/288 (26%), Positives = 106/288 (36%), Gaps = 7/288 (2%)

Query: 258  ADTISEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAA 317
            A T+    +   P   ++ A     P +  + A +   P +  S AA    P +  S AA
Sbjct: 959  AITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAA 1018

Query: 318  QRRDPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAVQRRHPADTMSEAAQRRDPADT 377
                P +  S AA    P +  S A     P +  S A     P +  S AA    P + 
Sbjct: 1019 AVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEP 1078

Query: 378  MSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAAQRR 437
             S AA    P +  S AA    P +  S AA    P +  S AA    P +  S AA   
Sbjct: 1079 TSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVP 1138

Query: 438  DPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEAVQRRHPADPMSEAAQRRDLADTMSE 497
             P +    A     P ++ S A     P ++ S A     PA+  S AA    L +  S 
Sbjct: 1139 TPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSP 1198

Query: 498  AAQRRDP-------EDTMSEAAQRRDPADAMSEAAQRRDPEDTMSEVA 538
            AA    P       E+  S AA      +  S AA   +PE+  S  A
Sbjct: 1199 AASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAA 1246



 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 74/327 (22%), Positives = 116/327 (35%)

Query: 23   PADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRRHPADTMSEAAQRRHPADTMSEA 82
            P   ++ A     P +  + A +   P +  S       P +  S AA    P +  S A
Sbjct: 971  PEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1030

Query: 83   VQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAAQRRHPAD 142
                 P +  S AA    P +  S A     P +  S AA    P +  S AA    P +
Sbjct: 1031 AAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEE 1090

Query: 143  TMSEAVQRRHPADTMSEAVQRRDPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAAQR 202
              S A     P +  S A     P +  S A     P +  S AA    P +    A   
Sbjct: 1091 PTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAV 1150

Query: 203  RDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTIS 262
              P ++ S A     P ++ S AA    PA++ S AA      +  S AA    PA  ++
Sbjct: 1151 PTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVA 1210

Query: 263  EAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDP 322
               +   PA ++  + +    A  +S   +   PA  +    +    A  +    +   P
Sbjct: 1211 TLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSP 1270

Query: 323  ADTMSEAAQRRDPADTMSEAVQRRHPA 349
            A ++    +   PA  +S   +   PA
Sbjct: 1271 AASVPTPEEPASPAAAVSNLEEPASPA 1297


>gi|239757530 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 435

 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 64/223 (28%), Positives = 92/223 (41%), Gaps = 44/223 (19%)

Query: 153 PADTMSEAVQRRDPADTMSE---AVQRRHPADTMSE---AAQRRHPADTMSE---AAQRR 203
           P    S A  + DP D M +   A  +  P D M +   A  +  P D M +   A  + 
Sbjct: 217 PTGKTSIATAQSDPMDVMQDQSIATAQSDPTDVMQDQSIATAQSDPTDVMQDQSIATAQS 276

Query: 204 DPADTMSE----AAQRRDPADTISE---AAQRRDPADTMSEAAQRRHPADTMSEAAQRRD 256
           DP D M +     AQR DP D + +   A  + DP D M +           S A  + D
Sbjct: 277 DPTDVMQDQSIATAQRSDPTDVMQDQSIATAQSDPTDVMQD----------QSIATAQSD 326

Query: 257 PADTISE---AAQRRDPADTMSE---AAQRRDPADTISE---AAQRRDPADTMSE---AA 304
           P D + +   A  + DP D M +   A  + DP D + +   A  + DP D M +   A 
Sbjct: 327 PTDVMQDRSIATAQSDPTDVMQDRSIATAQSDPTDVMQDRSIATAQSDPTDVMQDRSIAT 386

Query: 305 QRRHPADTMSE---AAQRRDPADTMSE---AAQRRDPADTMSE 341
            +  P D M +   A  + DP D M +   A  + DP D M +
Sbjct: 387 AQSDPTDVMQDRSIATAQSDPTDVMQDRSIATAQSDPTDVMQD 429



 Score = 73.9 bits (180), Expect = 3e-13
 Identities = 64/223 (28%), Positives = 91/223 (40%), Gaps = 44/223 (19%)

Query: 218 PADTISEAAQRRDPADTMSE---AAQRRHPADTMSE---AAQRRDPADTISE---AAQRR 268
           P    S A  + DP D M +   A  +  P D M +   A  + DP D + +   A  + 
Sbjct: 217 PTGKTSIATAQSDPMDVMQDQSIATAQSDPTDVMQDQSIATAQSDPTDVMQDQSIATAQS 276

Query: 269 DPADTMSE----AAQRRDPADTISE---AAQRRDPADTMSEAAQRRHPADTMSEAAQRRD 321
           DP D M +     AQR DP D + +   A  + DP D M +           S A  + D
Sbjct: 277 DPTDVMQDQSIATAQRSDPTDVMQDQSIATAQSDPTDVMQD----------QSIATAQSD 326

Query: 322 PADTMSE---AAQRRDPADTMSE---AVQRRHPADTMSE---AVQRRHPADTMSE---AA 369
           P D M +   A  + DP D M +   A  +  P D M +   A  +  P D M +   A 
Sbjct: 327 PTDVMQDRSIATAQSDPTDVMQDRSIATAQSDPTDVMQDRSIATAQSDPTDVMQDRSIAT 386

Query: 370 QRRDPADTMSE---AAQRRHPADTMSE---AAQRRDPADTMSE 406
            + DP D M +   A  +  P D M +   A  + DP D M +
Sbjct: 387 AQSDPTDVMQDRSIATAQSDPTDVMQDRSIATAQSDPTDVMQD 429



 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 63/217 (29%), Positives = 90/217 (41%), Gaps = 32/217 (14%)

Query: 348 PADTMSEAVQRRHPADTMSE---AAQRRDPADTMSE---AAQRRHPADTMSE---AAQRR 398
           P    S A  +  P D M +   A  + DP D M +   A  +  P D M +   A  + 
Sbjct: 217 PTGKTSIATAQSDPMDVMQDQSIATAQSDPTDVMQDQSIATAQSDPTDVMQDQSIATAQS 276

Query: 399 DPADTMSE----AAQRRHPADTMSE---AAQRRHPADTMSE---AAQRRDPADTMSE--- 445
           DP D M +     AQR  P D M +   A  +  P D M +   A  + DP D M +   
Sbjct: 277 DPTDVMQDQSIATAQRSDPTDVMQDQSIATAQSDPTDVMQDQSIATAQSDPTDVMQDRSI 336

Query: 446 AAQRRDPADTMSEAAQRRHPADTTSEAVQRRHPADPMSEAAQRRDLADTMSEAAQRRDPE 505
           A  + DP D M + +     +D T + +Q R  A   S+     D+    S A  + DP 
Sbjct: 337 ATAQSDPTDVMQDRSIATAQSDPT-DVMQDRSIATAQSDPT---DVMQDRSIATAQSDPT 392

Query: 506 DTMSE---AAQRRDPADAMSE---AAQRRDPEDTMSE 536
           D M +   A  + DP D M +   A  + DP D M +
Sbjct: 393 DVMQDRSIATAQSDPTDVMQDRSIATAQSDPTDVMQD 429


>gi|239752052 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 435

 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 64/223 (28%), Positives = 92/223 (41%), Gaps = 44/223 (19%)

Query: 153 PADTMSEAVQRRDPADTMSE---AVQRRHPADTMSE---AAQRRHPADTMSE---AAQRR 203
           P    S A  + DP D M +   A  +  P D M +   A  +  P D M +   A  + 
Sbjct: 217 PTGKTSIATAQSDPMDVMQDQSIATAQSDPTDVMQDQSIATAQSDPTDVMQDQSIATAQS 276

Query: 204 DPADTMSE----AAQRRDPADTISE---AAQRRDPADTMSEAAQRRHPADTMSEAAQRRD 256
           DP D M +     AQR DP D + +   A  + DP D M +           S A  + D
Sbjct: 277 DPTDVMQDQSIATAQRSDPTDVMQDQSIATAQSDPTDVMQD----------QSIATAQSD 326

Query: 257 PADTISE---AAQRRDPADTMSE---AAQRRDPADTISE---AAQRRDPADTMSE---AA 304
           P D + +   A  + DP D M +   A  + DP D + +   A  + DP D M +   A 
Sbjct: 327 PTDVMQDRSIATAQSDPTDVMQDRSIATAQSDPTDVMQDRSIATAQSDPTDVMQDRSIAT 386

Query: 305 QRRHPADTMSE---AAQRRDPADTMSE---AAQRRDPADTMSE 341
            +  P D M +   A  + DP D M +   A  + DP D M +
Sbjct: 387 AQSDPTDVMQDRSIATAQSDPTDVMQDRSIATAQSDPTDVMQD 429



 Score = 73.9 bits (180), Expect = 3e-13
 Identities = 64/223 (28%), Positives = 91/223 (40%), Gaps = 44/223 (19%)

Query: 218 PADTISEAAQRRDPADTMSE---AAQRRHPADTMSE---AAQRRDPADTISE---AAQRR 268
           P    S A  + DP D M +   A  +  P D M +   A  + DP D + +   A  + 
Sbjct: 217 PTGKTSIATAQSDPMDVMQDQSIATAQSDPTDVMQDQSIATAQSDPTDVMQDQSIATAQS 276

Query: 269 DPADTMSE----AAQRRDPADTISE---AAQRRDPADTMSEAAQRRHPADTMSEAAQRRD 321
           DP D M +     AQR DP D + +   A  + DP D M +           S A  + D
Sbjct: 277 DPTDVMQDQSIATAQRSDPTDVMQDQSIATAQSDPTDVMQD----------QSIATAQSD 326

Query: 322 PADTMSE---AAQRRDPADTMSE---AVQRRHPADTMSE---AVQRRHPADTMSE---AA 369
           P D M +   A  + DP D M +   A  +  P D M +   A  +  P D M +   A 
Sbjct: 327 PTDVMQDRSIATAQSDPTDVMQDRSIATAQSDPTDVMQDRSIATAQSDPTDVMQDRSIAT 386

Query: 370 QRRDPADTMSE---AAQRRHPADTMSE---AAQRRDPADTMSE 406
            + DP D M +   A  +  P D M +   A  + DP D M +
Sbjct: 387 AQSDPTDVMQDRSIATAQSDPTDVMQDRSIATAQSDPTDVMQD 429



 Score = 70.9 bits (172), Expect = 3e-12
 Identities = 63/217 (29%), Positives = 90/217 (41%), Gaps = 32/217 (14%)

Query: 348 PADTMSEAVQRRHPADTMSE---AAQRRDPADTMSE---AAQRRHPADTMSE---AAQRR 398
           P    S A  +  P D M +   A  + DP D M +   A  +  P D M +   A  + 
Sbjct: 217 PTGKTSIATAQSDPMDVMQDQSIATAQSDPTDVMQDQSIATAQSDPTDVMQDQSIATAQS 276

Query: 399 DPADTMSE----AAQRRHPADTMSE---AAQRRHPADTMSE---AAQRRDPADTMSE--- 445
           DP D M +     AQR  P D M +   A  +  P D M +   A  + DP D M +   
Sbjct: 277 DPTDVMQDQSIATAQRSDPTDVMQDQSIATAQSDPTDVMQDQSIATAQSDPTDVMQDRSI 336

Query: 446 AAQRRDPADTMSEAAQRRHPADTTSEAVQRRHPADPMSEAAQRRDLADTMSEAAQRRDPE 505
           A  + DP D M + +     +D T + +Q R  A   S+     D+    S A  + DP 
Sbjct: 337 ATAQSDPTDVMQDRSIATAQSDPT-DVMQDRSIATAQSDPT---DVMQDRSIATAQSDPT 392

Query: 506 DTMSE---AAQRRDPADAMSE---AAQRRDPEDTMSE 536
           D M +   A  + DP D M +   A  + DP D M +
Sbjct: 393 DVMQDRSIATAQSDPTDVMQDRSIATAQSDPTDVMQD 429


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 98/525 (18%), Positives = 164/525 (31%), Gaps = 38/525 (7%)

Query: 10  PADTMSEAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRRHPADTMSEA 69
           P  T S     + PA T ++      P +      +   P  T S P   + PA T  + 
Sbjct: 249 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 308

Query: 70  AQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPAD 129
                P +      +   P      A   + PA T       + PA T  +      P +
Sbjct: 309 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP-----KEPAPTAPKKPAPTTPKE 363

Query: 130 TMSEAAQRRHPADTMSEA---VQRRHPADTMSEAVQRRDPADTMSEAVQR--RHPADTMS 184
                 +   P  T   +    +   P  T S     ++PA T +++     + P+ T +
Sbjct: 364 PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 423

Query: 185 EAAQRRHPADTMSEAAQRRDPADTMSEA-AQRRDPADTISEAAQRRDPADTMSEAAQRRH 243
           +      P +      ++  P      A    ++PA T +     + PA T  +      
Sbjct: 424 KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT-----KKPAPTTPKEPAPTT 478

Query: 244 PADTMSEAAQRRDPADTISEAAQRRD-PADTMSEAAQRRDPADTISEAAQRRDPADTMSE 302
           P +T     ++  P      A    + PA T  E      P +      +  +PA T  +
Sbjct: 479 PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE--EPAPTTPK 536

Query: 303 AAQRRHPAD----TMSEAAQR--RDPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAV 356
           AA    P +    T  E A    ++PA T  +      P  T    ++   P      A 
Sbjct: 537 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 596

Query: 357 QRRHPADTMSEAAQRRD-PADTMSEA---AQRRHPADTMSEAAQRRDPADTMSEAAQRRH 412
           +   P  T    +   D PA T  +       + PA T  +      P  T     +   
Sbjct: 597 KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPA 656

Query: 413 PADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEA 472
           P      A +   P  T       + P  T S+      P +T       + PA TT + 
Sbjct: 657 PTTPKKPAPKELAPTTT-------KGPTSTTSDKPAPTTPKETAPTTP--KEPAPTTPKK 707

Query: 473 VQRRHPADPMSEAAQRRDLADTMSEAAQRRDPEDTMSEAAQRRDP 517
                P  P    ++      T       + P+++  E +    P
Sbjct: 708 PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTP 752



 Score = 37.7 bits (86), Expect = 0.027
 Identities = 55/291 (18%), Positives = 103/291 (35%), Gaps = 25/291 (8%)

Query: 271 ADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPA-DTMS-EAAQRRDPADTMSE 328
           +DT  E +   +   T+           T ++  ++   A +T S E    +D A T   
Sbjct: 134 SDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV 193

Query: 329 AAQ--------RRDPADTMSEAVQRRHPADTMSEAVQRRHPADTMSEAAQRRDPADTMSE 380
            A+         + PA T  +      P +  S   +   P    S     ++PA T ++
Sbjct: 194 LAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK 253

Query: 381 AAQR--RHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAAQRRD 438
           +A    + PA T ++      P +      +   P  T S     + PA T  +      
Sbjct: 254 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 313

Query: 439 PADTMSEAAQRRDPADTMSEAAQRRHPADTTSE-----AVQRRHPADPMSEA-AQRRDLA 492
           P +      +   P      A   + PA TT +     A ++  P  P   A    ++ A
Sbjct: 314 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 373

Query: 493 DTMSEAAQRRDPED-----TMSEAAQRRDPADAMSEAAQR--RDPEDTMSE 536
            T ++      P++     T S     ++PA   +++A    ++P  T ++
Sbjct: 374 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 424


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 98/525 (18%), Positives = 164/525 (31%), Gaps = 38/525 (7%)

Query: 10  PADTMSEAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRRHPADTMSEA 69
           P  T S     + PA T ++      P +      +   P  T S P   + PA T  + 
Sbjct: 290 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 349

Query: 70  AQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPAD 129
                P +      +   P      A   + PA T       + PA T  +      P +
Sbjct: 350 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP-----KEPAPTAPKKPAPTTPKE 404

Query: 130 TMSEAAQRRHPADTMSEA---VQRRHPADTMSEAVQRRDPADTMSEAVQR--RHPADTMS 184
                 +   P  T   +    +   P  T S     ++PA T +++     + P+ T +
Sbjct: 405 PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 464

Query: 185 EAAQRRHPADTMSEAAQRRDPADTMSEA-AQRRDPADTISEAAQRRDPADTMSEAAQRRH 243
           +      P +      ++  P      A    ++PA T +     + PA T  +      
Sbjct: 465 KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT-----KKPAPTTPKEPAPTT 519

Query: 244 PADTMSEAAQRRDPADTISEAAQRRD-PADTMSEAAQRRDPADTISEAAQRRDPADTMSE 302
           P +T     ++  P      A    + PA T  E      P +      +  +PA T  +
Sbjct: 520 PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE--EPAPTTPK 577

Query: 303 AAQRRHPAD----TMSEAAQR--RDPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAV 356
           AA    P +    T  E A    ++PA T  +      P  T    ++   P      A 
Sbjct: 578 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 637

Query: 357 QRRHPADTMSEAAQRRD-PADTMSEA---AQRRHPADTMSEAAQRRDPADTMSEAAQRRH 412
           +   P  T    +   D PA T  +       + PA T  +      P  T     +   
Sbjct: 638 KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPA 697

Query: 413 PADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEA 472
           P      A +   P  T       + P  T S+      P +T       + PA TT + 
Sbjct: 698 PTTPKKPAPKELAPTTT-------KGPTSTTSDKPAPTTPKETAPTTP--KEPAPTTPKK 748

Query: 473 VQRRHPADPMSEAAQRRDLADTMSEAAQRRDPEDTMSEAAQRRDP 517
                P  P    ++      T       + P+++  E +    P
Sbjct: 749 PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTP 793



 Score = 37.7 bits (86), Expect = 0.027
 Identities = 55/291 (18%), Positives = 103/291 (35%), Gaps = 25/291 (8%)

Query: 271 ADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPA-DTMS-EAAQRRDPADTMSE 328
           +DT  E +   +   T+           T ++  ++   A +T S E    +D A T   
Sbjct: 175 SDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV 234

Query: 329 AAQ--------RRDPADTMSEAVQRRHPADTMSEAVQRRHPADTMSEAAQRRDPADTMSE 380
            A+         + PA T  +      P +  S   +   P    S     ++PA T ++
Sbjct: 235 LAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK 294

Query: 381 AAQR--RHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAAQRRD 438
           +A    + PA T ++      P +      +   P  T S     + PA T  +      
Sbjct: 295 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 354

Query: 439 PADTMSEAAQRRDPADTMSEAAQRRHPADTTSE-----AVQRRHPADPMSEA-AQRRDLA 492
           P +      +   P      A   + PA TT +     A ++  P  P   A    ++ A
Sbjct: 355 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 414

Query: 493 DTMSEAAQRRDPED-----TMSEAAQRRDPADAMSEAAQR--RDPEDTMSE 536
            T ++      P++     T S     ++PA   +++A    ++P  T ++
Sbjct: 415 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 465


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 98/525 (18%), Positives = 164/525 (31%), Gaps = 38/525 (7%)

Query: 10  PADTMSEAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRRHPADTMSEA 69
           P  T S     + PA T ++      P +      +   P  T S P   + PA T  + 
Sbjct: 342 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 401

Query: 70  AQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPAD 129
                P +      +   P      A   + PA T       + PA T  +      P +
Sbjct: 402 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP-----KEPAPTAPKKPAPTTPKE 456

Query: 130 TMSEAAQRRHPADTMSEA---VQRRHPADTMSEAVQRRDPADTMSEAVQR--RHPADTMS 184
                 +   P  T   +    +   P  T S     ++PA T +++     + P+ T +
Sbjct: 457 PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 516

Query: 185 EAAQRRHPADTMSEAAQRRDPADTMSEA-AQRRDPADTISEAAQRRDPADTMSEAAQRRH 243
           +      P +      ++  P      A    ++PA T +     + PA T  +      
Sbjct: 517 KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT-----KKPAPTTPKEPAPTT 571

Query: 244 PADTMSEAAQRRDPADTISEAAQRRD-PADTMSEAAQRRDPADTISEAAQRRDPADTMSE 302
           P +T     ++  P      A    + PA T  E      P +      +  +PA T  +
Sbjct: 572 PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE--EPAPTTPK 629

Query: 303 AAQRRHPAD----TMSEAAQR--RDPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAV 356
           AA    P +    T  E A    ++PA T  +      P  T    ++   P      A 
Sbjct: 630 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 689

Query: 357 QRRHPADTMSEAAQRRD-PADTMSEA---AQRRHPADTMSEAAQRRDPADTMSEAAQRRH 412
           +   P  T    +   D PA T  +       + PA T  +      P  T     +   
Sbjct: 690 KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPA 749

Query: 413 PADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEA 472
           P      A +   P  T       + P  T S+      P +T       + PA TT + 
Sbjct: 750 PTTPKKPAPKELAPTTT-------KGPTSTTSDKPAPTTPKETAPTTP--KEPAPTTPKK 800

Query: 473 VQRRHPADPMSEAAQRRDLADTMSEAAQRRDPEDTMSEAAQRRDP 517
                P  P    ++      T       + P+++  E +    P
Sbjct: 801 PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTP 845



 Score = 37.7 bits (86), Expect = 0.027
 Identities = 55/291 (18%), Positives = 103/291 (35%), Gaps = 25/291 (8%)

Query: 271 ADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPA-DTMS-EAAQRRDPADTMSE 328
           +DT  E +   +   T+           T ++  ++   A +T S E    +D A T   
Sbjct: 227 SDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV 286

Query: 329 AAQ--------RRDPADTMSEAVQRRHPADTMSEAVQRRHPADTMSEAAQRRDPADTMSE 380
            A+         + PA T  +      P +  S   +   P    S     ++PA T ++
Sbjct: 287 LAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK 346

Query: 381 AAQR--RHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAAQRRD 438
           +A    + PA T ++      P +      +   P  T S     + PA T  +      
Sbjct: 347 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 406

Query: 439 PADTMSEAAQRRDPADTMSEAAQRRHPADTTSE-----AVQRRHPADPMSEA-AQRRDLA 492
           P +      +   P      A   + PA TT +     A ++  P  P   A    ++ A
Sbjct: 407 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 466

Query: 493 DTMSEAAQRRDPED-----TMSEAAQRRDPADAMSEAAQR--RDPEDTMSE 536
            T ++      P++     T S     ++PA   +++A    ++P  T ++
Sbjct: 467 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 517


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 98/525 (18%), Positives = 164/525 (31%), Gaps = 38/525 (7%)

Query: 10  PADTMSEAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRRHPADTMSEA 69
           P  T S     + PA T ++      P +      +   P  T S P   + PA T  + 
Sbjct: 383 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 442

Query: 70  AQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPAD 129
                P +      +   P      A   + PA T       + PA T  +      P +
Sbjct: 443 PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP-----KEPAPTAPKKPAPTTPKE 497

Query: 130 TMSEAAQRRHPADTMSEA---VQRRHPADTMSEAVQRRDPADTMSEAVQR--RHPADTMS 184
                 +   P  T   +    +   P  T S     ++PA T +++     + P+ T +
Sbjct: 498 PAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 557

Query: 185 EAAQRRHPADTMSEAAQRRDPADTMSEA-AQRRDPADTISEAAQRRDPADTMSEAAQRRH 243
           +      P +      ++  P      A    ++PA T +     + PA T  +      
Sbjct: 558 KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT-----KKPAPTTPKEPAPTT 612

Query: 244 PADTMSEAAQRRDPADTISEAAQRRD-PADTMSEAAQRRDPADTISEAAQRRDPADTMSE 302
           P +T     ++  P      A    + PA T  E      P +      +  +PA T  +
Sbjct: 613 PKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE--EPAPTTPK 670

Query: 303 AAQRRHPAD----TMSEAAQR--RDPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAV 356
           AA    P +    T  E A    ++PA T  +      P  T    ++   P      A 
Sbjct: 671 AAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAP 730

Query: 357 QRRHPADTMSEAAQRRD-PADTMSEA---AQRRHPADTMSEAAQRRDPADTMSEAAQRRH 412
           +   P  T    +   D PA T  +       + PA T  +      P  T     +   
Sbjct: 731 KELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPA 790

Query: 413 PADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEA 472
           P      A +   P  T       + P  T S+      P +T       + PA TT + 
Sbjct: 791 PTTPKKPAPKELAPTTT-------KGPTSTTSDKPAPTTPKETAPTTP--KEPAPTTPKK 841

Query: 473 VQRRHPADPMSEAAQRRDLADTMSEAAQRRDPEDTMSEAAQRRDP 517
                P  P    ++      T       + P+++  E +    P
Sbjct: 842 PAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTP 886



 Score = 37.7 bits (86), Expect = 0.027
 Identities = 55/291 (18%), Positives = 103/291 (35%), Gaps = 25/291 (8%)

Query: 271 ADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPA-DTMS-EAAQRRDPADTMSE 328
           +DT  E +   +   T+           T ++  ++   A +T S E    +D A T   
Sbjct: 268 SDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKV 327

Query: 329 AAQ--------RRDPADTMSEAVQRRHPADTMSEAVQRRHPADTMSEAAQRRDPADTMSE 380
            A+         + PA T  +      P +  S   +   P    S     ++PA T ++
Sbjct: 328 LAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTK 387

Query: 381 AAQR--RHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAAQRRD 438
           +A    + PA T ++      P +      +   P  T S     + PA T  +      
Sbjct: 388 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 447

Query: 439 PADTMSEAAQRRDPADTMSEAAQRRHPADTTSE-----AVQRRHPADPMSEA-AQRRDLA 492
           P +      +   P      A   + PA TT +     A ++  P  P   A    ++ A
Sbjct: 448 PKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPA 507

Query: 493 DTMSEAAQRRDPED-----TMSEAAQRRDPADAMSEAAQR--RDPEDTMSE 536
            T ++      P++     T S     ++PA   +++A    ++P  T ++
Sbjct: 508 PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTK 558


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 95/493 (19%), Positives = 167/493 (33%), Gaps = 38/493 (7%)

Query: 4    AVQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRRHPA 63
            A+ RR  + + S+         + +E++    P   T+    R  P   T      R  +
Sbjct: 1631 ALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRS 1690

Query: 64   DTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQ 123
               S    R+      S +        + +    RR P+      V    PA+    + +
Sbjct: 1691 SRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPS------VSSPEPAEKSRSSRR 1744

Query: 124  RRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSE---AVQRRDPADTMSEAVQRRHPA 180
            RR  +   ++   RR  + +      +R  + +  E     +RRD + +     +RR  +
Sbjct: 1745 RRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRS 1804

Query: 181  DTMSEAAQRRHPAD---TMSEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPA----- 232
             + S   +RR       + S A Q      +     + R P  +   +  R  PA     
Sbjct: 1805 RSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRS 1864

Query: 233  -DTMSEAAQRRHPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRDPADTISEAA 291
                S A  RR  + T      RR      S  ++RR  + T     + R  A  +S   
Sbjct: 1865 RSRASPATHRRSRSRT--PLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRR 1922

Query: 292  QRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDP-----ADTMSEAVQRR 346
             R          ++ R P  T    ++ R P  T   +  R  P     + + +  + RR
Sbjct: 1923 SRSRTPPVTRRRSRSRTP--TTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRR 1980

Query: 347  HPADTMSEAVQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQR--------- 397
                  S   +RR  + T S   +RR  + T S   +RR  + T     +R         
Sbjct: 1981 RSRSRTSPVTRRRSRSRT-SPVTRRRSRSRT-SPVTRRRSRSRTPPAIRRRSRSRTPLLP 2038

Query: 398  RDPADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMS 457
            R  + + S  A RR         A+ +        A +RR  + + S+ ++   P  T +
Sbjct: 2039 RKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRN 2098

Query: 458  EAAQRRHPADTTS 470
             +  R  P    S
Sbjct: 2099 HSGSRTPPVALNS 2111



 Score = 55.8 bits (133), Expect = 9e-08
 Identities = 98/500 (19%), Positives = 175/500 (35%), Gaps = 47/500 (9%)

Query: 28   SEAAQRRHPADTTSEAAQRRHPADTTSEPVQRRHPA------DTMSEAAQRRHPADTMSE 81
            S + Q R  +D++ ++  +      T  P+++R  +      D+ S  + RR  + +  E
Sbjct: 1550 SASPQERSESDSSPDSKAK------TRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPE 1603

Query: 82   AVQRRHPAD-TMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAAQRRHP 140
               +   A    S +     P      A+ RR  + + S+         + +E++    P
Sbjct: 1604 VKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPP 1663

Query: 141  ADTMSEAVQRRHPADTMSEAVQRRDPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAA 200
                +    R  P          R  +   S  + R+      S +A       + +   
Sbjct: 1664 KSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPR 1723

Query: 201  QRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADT 260
             RR P+ +  E      PA+    + +RR  +   ++   RR  + +      +R  + +
Sbjct: 1724 HRRSPSVSSPE------PAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRS 1777

Query: 261  ISE---AAQRRDPADTMSEAAQRRDPADTISEAAQRRDPAD---TMSEAAQRRHPADTMS 314
              E     +RRD + +    ++RR  + + S   +RR       + S A Q      +  
Sbjct: 1778 RREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRR 1837

Query: 315  EAAQRRDPADTMSEAAQRRDPA------DTMSEAVQRRHPADTMSEAVQRRHPADTMSEA 368
               + R P  +   +  R  PA         S A  RR  + T    + RR      S  
Sbjct: 1838 RRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRT--PLISRRRSRSRTSPV 1895

Query: 369  AQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQR-RHPADTMSEAAQRRHPA 427
            ++RR  + T   +  RR      S  ++RR  + T     +R R    T    ++ R P 
Sbjct: 1896 SRRRSRSRT---SVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPP 1952

Query: 428  DTMSEAAQRRDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEAVQRRHPADPMSEAAQ 487
             T   +  R  P         RR      S   +RR  + T+   V RR      S   +
Sbjct: 1953 VTRRRSRSRTPP-------VTRRRSRSRTSPITRRRSRSRTS--PVTRRRSRSRTSPVTR 2003

Query: 488  RRDLADTMSEAAQRRDPEDT 507
            RR  + T S   +RR    T
Sbjct: 2004 RRSRSRT-SPVTRRRSRSRT 2022



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 89/420 (21%), Positives = 147/420 (35%), Gaps = 37/420 (8%)

Query: 3    EAVQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRRHP 62
            E   R  P    S +V    PA+    + +RR  +   ++   RR  + +      +R  
Sbjct: 1715 ETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQR-- 1772

Query: 63   ADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPAD---TMS 119
                S +  RR    T     +RR  + +    ++RR  + + S   +RR       + S
Sbjct: 1773 ----SRSRSRREKTRT----TRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRS 1824

Query: 120  EAAQRRHPADTMSEAAQRRHPADTMSEAVQRRHPA------DTMSEAVQRRDPADTMSEA 173
             A Q      +     + R P  +   +  R  PA         S A  RR  + T    
Sbjct: 1825 PARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRT--PL 1882

Query: 174  VQRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPAD 233
            + RR      S  ++RR  + T     + R  A  +S    R          ++ R P  
Sbjct: 1883 ISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTP-- 1940

Query: 234  TMSEAAQRRHPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRDPADTISEAAQR 293
            T    ++ R P  T   +  R  P         RR      S   +RR  + T S   +R
Sbjct: 1941 TTRRRSRSRTPPVTRRRSRSRTPP-------VTRRRSRSRTSPITRRRSRSRT-SPVTRR 1992

Query: 294  RDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAVQRRHPADTMS 353
            R  + T      RR      S   +RR  + T   A +RR  + T    + R+       
Sbjct: 1993 RSRSRT--SPVTRRRSRSRTSPVTRRRSRSRT-PPAIRRRSRSRT--PLLPRKRSRSRSP 2047

Query: 354  EAVQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRHP 413
             A++RR  + T   A  +R        A +RR  + + S+ ++   P  T + +  R  P
Sbjct: 2048 LAIRRRSRSRTPRTARGKRS-LTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPP 2106



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 64/354 (18%), Positives = 120/354 (33%), Gaps = 16/354 (4%)

Query: 184  SEAAQRRHPADTMSEA-AQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRR 242
            S + Q R  +D+  ++ A+ R P    S +    +  D+ S  + RR  + +  E   + 
Sbjct: 1550 SASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPE-VDSKSRLSPRRSRSGSSPEVKDKP 1608

Query: 243  HPAD-TMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMS 301
              A    S +    +P      A  RR  + + S+         + +E++    P    +
Sbjct: 1609 RAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTA 1668

Query: 302  EAAQRRHPAD-TMSEAAQRRDPADTMSEAAQRRDPADTMSEAVQRR-HPADTMSEAVQRR 359
                R  P   T S    RR         + R  P  T    + RR   A +  E   R 
Sbjct: 1669 RRGSRSSPEPKTKSRTPPRR--------RSSRSSPELTRKARLSRRSRSASSSPETRSRT 1720

Query: 360  HPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSE 419
             P    S +    +PA+    + +RR  +   ++   RR  + +      +R  + +  E
Sbjct: 1721 PPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRRE 1780

Query: 420  ---AAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEAVQRR 476
                 +RR  + +    ++RR  + + S   +RR         +  R  +  TS   +R 
Sbjct: 1781 KTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRG 1840

Query: 477  HPADPMSEAAQRRDLADTMSEAAQRRDPEDTMSEAAQRRDPADAMSEAAQRRDP 530
                P +   + R           R          ++ R P  +   +  R  P
Sbjct: 1841 RSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSP 1894



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 70/377 (18%), Positives = 131/377 (34%), Gaps = 39/377 (10%)

Query: 163 RRDPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTI 222
           +R   +    A +   P   + E++  R P     +  +++D       ++ RR+   + 
Sbjct: 154 QRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSS 213

Query: 223 SEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRD 282
            +   R +     SE+ +R+H + T     + +D         +R+    T      RR 
Sbjct: 214 KKKKHRSE-----SESKKRKHRSPTPKSKRKSKD--------KKRKRSRSTTPAPKSRRA 260

Query: 283 PADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMSEA 342
              T +++A   D + + S +A     A T + A   R P    S A+ RR   D     
Sbjct: 261 HRSTSADSASSSDTSRSRSRSA----AAKTHTTALAGRSP----SPASGRRGEGDAPFS- 311

Query: 343 VQRRHPADTMSEAVQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPAD 402
                P  T ++       A     +       D   ++A R  P+   S       PA 
Sbjct: 312 ----EPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGP-EPPAP 366

Query: 403 TMSEAAQRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAA-Q 461
           T   A +       ++     + P +  SEA+  RD +   S     + P  + SE++  
Sbjct: 367 TPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKS---PEKLPQSSSSESSPP 423

Query: 462 RRHPADTTSEAVQRRHPADPMSEAAQRRDLADT-----MSEAAQRRDPEDTMSEA---AQ 513
              P   +  A        P       R+++ +      S    +RD   + + +    +
Sbjct: 424 SPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGR 483

Query: 514 RRDPADAMSEAAQRRDP 530
            R PA A    ++ R P
Sbjct: 484 SRSPATAKRGRSRSRTP 500



 Score = 38.1 bits (87), Expect = 0.020
 Identities = 108/583 (18%), Positives = 187/583 (32%), Gaps = 75/583 (12%)

Query: 4    AVQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRRHPA 63
            A++RR  + + S+  +   P  T + +  R  P    S           +  P+ R    
Sbjct: 2074 AIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSP 2133

Query: 64   DTMSEAAQRRHPADTMSEA-----------VQRRHPADTMSEAAQRRHPADTMSEAVQRR 112
              +      R P   + +A           +            AQ R      + ++   
Sbjct: 2134 GMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTA 2193

Query: 113  HPADTMSEA------AQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAVQRRDP 166
             P  +MS A      +Q   P   MS    R  PA  ++  +     A  M+ A  R   
Sbjct: 2194 RPPPSMSAAGLAARMSQVPAPVPLMS---LRTAPAANLASRIPAASAA-AMNLASARTPA 2249

Query: 167  ADTMSEAVQRRHPADT--MSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTI-- 222
              T       R PA    M+ A+ R   A +    A  R P       A  R PA     
Sbjct: 2250 IPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAAL 2309

Query: 223  ---------------SEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPA-DTISEAAQ 266
                           S +   + PA       +  H    ++ A  R   A    S  + 
Sbjct: 2310 SLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSA 2369

Query: 267  RRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRD----P 322
            R  PA + +     R P       + R  P   + + A+ R P    S++    +    P
Sbjct: 2370 RMAPALSGANLTSPRVPLSAYERVSGRTSPP--LLDRARSRTPPSAPSQSRMTSERAPSP 2427

Query: 323  ADTMSEAA----------QRRDPADTMSEAVQRRHPADTM----SEAVQRRHPADTMSEA 368
            +  M +A           Q R P  +      R   A T     S+++     A T S A
Sbjct: 2428 SSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSA 2487

Query: 369  AQRRD----PADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRR 424
                     PA  +  +     PA T    AQ+      +  A +RR  + + S ++   
Sbjct: 2488 GDHNGMLSVPAPGVPHSDVGEPPAST---GAQQPSALAALQPAKERRSSSSSSSSSS--- 2541

Query: 425  HPADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAAQRRHPADTTS--EAVQRRHPADPM 482
              + + S ++     +   S +           E A +R P+ T +  EAV+   P +P 
Sbjct: 2542 --SSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPT 2599

Query: 483  SEAAQRRDLADTMSEAAQRRDPEDTMSEAAQRRDPADAMSEAA 525
                +RR  + + S ++       + S ++     + + S ++
Sbjct: 2600 PAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2642



 Score = 36.2 bits (82), Expect = 0.078
 Identities = 70/378 (18%), Positives = 125/378 (33%), Gaps = 32/378 (8%)

Query: 163  RRDPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTI 222
            R  PA + +     R P       + R  P   + + A+ R P    S++    + A + 
Sbjct: 2370 RMAPALSGANLTSPRVPLSAYERVSGRTSPP--LLDRARSRTPPSAPSQSRMTSERAPSP 2427

Query: 223  SEAAQRRDPADTMSEAA-QRRHPADTMSEAAQRRDPADTI----SEAAQRRDPADTMSEA 277
            S    +      +  A  Q R P  +      R   A T     S++      A T S A
Sbjct: 2428 SSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSA 2487

Query: 278  AQRRD----PADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRR 333
                     PA  +  +     PA T    AQ+      +  A +RR  + + S ++   
Sbjct: 2488 GDHNGMLSVPAPGVPHSDVGEPPAST---GAQQPSALAALQPAKERRSSSSSSSSSSSSS 2544

Query: 334  DPADTMSEAVQRRHPADTMSEAVQRRHPADTMSEAAQRRDPADTMS--EAAQRRHPADTM 391
              + + S +      +   S +           E A +R P+ T +  EA +   P +  
Sbjct: 2545 SSSSSSSSS-----SSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPT 2599

Query: 392  SEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRD 451
                +RR  + + S ++     + + S ++         S ++     + + S ++    
Sbjct: 2600 PAKRKRRSSSSSSSSSSSSSSSSSSSSSSS---------SSSSSSSSSSSSSSSSSSSPS 2650

Query: 452  PADTMSEAAQRRHPADTTSEAVQRRHPADPMSEAAQRRDLADTMSEAAQRRDPEDTMSEA 511
            PA    +A  +  PA         R    P       RD         +RR P    S  
Sbjct: 2651 PAKPGPQALPK--PASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPR 2708

Query: 512  AQRRDPADAMSEAAQRRD 529
             Q+   ++  S   QR D
Sbjct: 2709 DQQSSSSERGSRRGQRGD 2726


>gi|60097902 filaggrin [Homo sapiens]
          Length = 4061

 Score = 59.3 bits (142), Expect = 9e-09
 Identities = 117/606 (19%), Positives = 191/606 (31%), Gaps = 78/606 (12%)

Query: 8    RHPADTMSEAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRRHPADTMS 67
            RH A    +   R HP  +        H     S      H + TTS+         + S
Sbjct: 3099 RHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGS 3158

Query: 68   EAAQR-----RHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRR---------- 112
             +A R         D+   +V R H A T ++ ++        SE  +R           
Sbjct: 3159 RSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQD 3218

Query: 113  -----HPADT--MSEAAQRRHPADTMSEAAQ-RRHPADTMSEAVQRRHPADTMSEAVQRR 164
                 H  D+   S +A R H      ++    RHP     +     H AD   ++  R 
Sbjct: 3219 SDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRH 3278

Query: 165  DPADTMSEAVQ----------RRHPADTMSEAAQRRHPADTMSEAAQR-RDPADTMSEAA 213
                +  +A             RH +     A   RH      +A+   RD     S  +
Sbjct: 3279 AETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGS 3338

Query: 214  QRRD--------PADTISEAAQRRDPADTMSEAAQRRH--------------PADTMSEA 251
            Q  D           ++S   Q      +  E+A+ R                    SE+
Sbjct: 3339 QASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSES 3398

Query: 252  AQRRDPADTISEAAQRRDPADTMSEAAQRRDPADTI--SEAAQRRDPADTMSEAAQRR-- 307
            A  R    T        + A   S  +  ++  DTI     + RR    +  E +  R  
Sbjct: 3399 AHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSG 3458

Query: 308  ----HPADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAVQRR---HPADTMSEAVQRRH 360
                H + T S+         + S +A R+   D  S    R    H  +  ++A   RH
Sbjct: 3459 HSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRH 3518

Query: 361  PADTMSEAAQRRDPADTMSEAAQ----RRHPADT--MSEAAQRRDPADTMSEAAQ-RRHP 413
                  ++A  R   +  S  +Q    + H  D+   S +A R        ++    RHP
Sbjct: 3519 SQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHP 3578

Query: 414  ADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEAV 473
                 + A   H A++  ++        +  +AA   + A     +A  RH +     A 
Sbjct: 3579 TSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQA---RSSAGERHGSHHQQSAD 3635

Query: 474  QRRHPADPMSEAAQR-RDLADTMSEAAQRRDPEDTMSEAAQRRDPADAMSEAAQRRDPED 532
              RH      +A+   RD     S  +Q  D E    ++  +   A   +   Q+   E 
Sbjct: 3636 SSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQES 3695

Query: 533  TMSEVA 538
            T    A
Sbjct: 3696 TRGRSA 3701



 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 94/545 (17%), Positives = 185/545 (33%), Gaps = 43/545 (7%)

Query: 9    HPADTMSEAVQRRHPADTMSEAAQR-----RHPADTTSEAAQRRHPADTTSEPVQRRHPA 63
            H + T S+         + S +A R     +   D +  +  R H A + ++  +     
Sbjct: 1194 HHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVG 1253

Query: 64   DTMSEAAQR-RHPADTMSE-AVQRRHPADT--MSEAAQRRHPADTMSEAVQ-RRHPADTM 118
               S  ++  RH   ++S+ +   RH  D+  +S +A R H   +  ++    RHP    
Sbjct: 1254 QEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQ 1313

Query: 119  SEAAQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTM---SEAVQRRDPADTMSEA-V 174
             + A   H AD+  ++      + +  +AV     A +        + +  AD+   + +
Sbjct: 1314 EDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGI 1373

Query: 175  QRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQ-RRDPADTISEAAQRRDPAD 233
              R  +  + ++  R      ++ +    + +DT S +A  +  P     + + R    +
Sbjct: 1374 GHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGE 1433

Query: 234  TMSEAAQRRHPADT--MSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRDPADTI---- 287
            +   +    +   +   SE+   +    T      R + A   S  +  +D  DTI    
Sbjct: 1434 SSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHP 1493

Query: 288  ---------SEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADT 338
                     S   Q  D +           P      +  +  P     +        D 
Sbjct: 1494 GSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDG 1553

Query: 339  MSEAVQRRHPADTMSEAVQRRHPADTMSEAA----QRRDPADTMSEAAQRRHPADT--MS 392
               +  R H   T   A   RH      E+A     RR  +    +     H  D+   S
Sbjct: 1554 SRHSGSRHHEPST--RAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRS 1611

Query: 393  EAAQRRDPADTMSEAAQ-RRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRD 451
            E+A R        ++    R+P     + A   H A++  ++  R     +  +AA  ++
Sbjct: 1612 ESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQE 1671

Query: 452  PA-DTMSEAAQRRHPA---DTTSEAVQRRHPADPMSEAAQRRDLADTMSEAAQRRDPEDT 507
             A  +  E    RH      +T     RR  +  + ++  R       S++    +  DT
Sbjct: 1672 QARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDT 1731

Query: 508  MSEAA 512
             S +A
Sbjct: 1732 QSVSA 1736



 Score = 55.8 bits (133), Expect = 9e-08
 Identities = 98/587 (16%), Positives = 188/587 (32%), Gaps = 66/587 (11%)

Query: 8    RHPADTMSEAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRRHPADTMS 67
            RH A    +   R HP           H            H + TTS+         + S
Sbjct: 1154 RHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGS 1213

Query: 68   EAAQRRHPADTMS-----EAVQRRHPADTMSEAAQR--------------RHPADTMS-E 107
             +A R+   D  S      +  R H A + +++++               RH   ++S +
Sbjct: 1214 RSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQD 1273

Query: 108  AVQRRHPADT--MSEAAQRRHPADTMSEAAQ-RRHPADTMSEAVQRRHPADTMSEAVQRR 164
            +   RH  D+  +S +A R H   +  ++    RHP     +     H AD+  ++    
Sbjct: 1274 SDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHH 1333

Query: 165  DPADTMSEAVQRRHPA-DTMSEAAQRRHPADTMS---EAAQRRDPADTMSEAAQRRDPAD 220
              + +  +AV     A  +  E    RH     S        R  +  + ++  R     
Sbjct: 1334 TESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGS 1393

Query: 221  TISEAAQRRDPADTMSEAA-------QRRHPADTMSEAAQRRDPADTI---------SEA 264
             ++ +    + +DT S +A       Q+ H      ++ +    + +          SE+
Sbjct: 1394 QVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSES 1453

Query: 265  AQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMS--EAAQRRDP 322
               +    T      R + A   S  +  +D  DT+     R HP  +    + +     
Sbjct: 1454 THGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTI-----RGHPGSSRGGRQGSYHEQS 1508

Query: 323  ADTMSEAAQRRD---PADTMSEAVQRRHPADTMSEAVQRRHPADTMSEAAQRRDPADTMS 379
             D    +        P      +  +  P     +        D    +  R     T  
Sbjct: 1509 VDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPST-- 1566

Query: 380  EAAQRRHPADTMSEAA----QRRDPADTMSEAAQRRHPADT--MSEAAQRRHPADTMSEA 433
             A   RH      E+A     RR  +    +     H  D+   SE+A R H      ++
Sbjct: 1567 RAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQS 1626

Query: 434  AQ-RRDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEAVQRRHPADPM---SEAAQRR 489
                R+P     + A     A++  ++  R     +  +A   +  A         ++ +
Sbjct: 1627 RHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQ 1686

Query: 490  DLADTMSEAAQ-RRDPEDTMSEAAQRRDPADAMSEAAQRRDPEDTMS 535
              AD+ +++   RR     + ++  R       S++    +  DT S
Sbjct: 1687 QSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQS 1733



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 96/549 (17%), Positives = 172/549 (31%), Gaps = 63/549 (11%)

Query: 21   RHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRRHPADTMSEAAQRRHPADTMS 80
            RH A    +   R HP  +        +     S      H + T S+         + S
Sbjct: 1802 RHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGS 1861

Query: 81   EAVQR-----RHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQ--RRHPADTMSE 133
             +V R     +   D    +  R H A + +++ +        S   +  R   +    +
Sbjct: 1862 RSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQD 1921

Query: 134  AAQRRHPADT--MSEAVQRRHPADTMSEAVQRRDPADTMSEAVQRRHPADTMSEAAQRRH 191
            +  + H  D+   S +  R H         Q RD +         RHP     + A   H
Sbjct: 1922 SDSQGHSEDSERWSGSASRNHLGSAWE---QSRDGS---------RHPGSHHEDRAGHGH 1969

Query: 192  PADTMSEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRH-------P 244
             AD+  ++  R   + +  +AA   + A   S A +R      +  A   RH        
Sbjct: 1970 SADSSRQSGTRHTESSSRGQAASSHEQAR--SSAGERHGSHHQLQSADSSRHSGIGHGQA 2027

Query: 245  ADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQ-RRDPADTISEAAQRRDPADTMSEA 303
            +  + ++  R       S++    + +DT S +AQ +  P     + + R    ++   +
Sbjct: 2028 SSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRS 2087

Query: 304  AQRRHPADT--MSEAAQRRDPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAVQRRHP 361
                +   T   SE+   +    T        D A   S     RH A    +   R HP
Sbjct: 2088 GSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSS-----RHSASQEGQDTIRGHP 2142

Query: 362  ADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRR---------- 411
              +                     H + T S+         + S +A R+          
Sbjct: 2143 GPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDG 2202

Query: 412  ------HPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRD------PADTMSEA 459
                  H  +  S A   RH      +++  R      S  +Q  D       ++  S +
Sbjct: 2203 SRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGS 2262

Query: 460  AQRRHPADTTSEAVQ-RRHPADPMSEAAQRRDLADTMSEAAQRRDPEDTMSEAAQRRDPA 518
            A R H      ++    RHP     + A     A++  ++        +  +AA   +  
Sbjct: 2263 ASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHE-- 2320

Query: 519  DAMSEAAQR 527
             A S A +R
Sbjct: 2321 QARSSAGER 2329



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 97/556 (17%), Positives = 176/556 (31%), Gaps = 65/556 (11%)

Query: 8    RHPADTMSEAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRRHPADTMS 67
            RH      +     HP  +        +            H + TTS+         + S
Sbjct: 2451 RHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGS 2510

Query: 68   EAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQ--RR 125
             +A R+   D  S         D    +  R H A + +++          SE  +  R 
Sbjct: 2511 RSASRQTRNDEQS--------GDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRN 2562

Query: 126  HPADTMSEAAQRRHPADT--MSEAVQRRHPADTMSEAVQRRDPADTMSEAVQRRHPADTM 183
              +    ++  + H  D+   S +  R H         Q RD +         RHP    
Sbjct: 2563 WGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQE---QLRDGS---------RHPRSHQ 2610

Query: 184  SEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRR- 242
             + A   H AD+  ++  R     +  +AA   + A   S A +R       S  + R  
Sbjct: 2611 EDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQAR--SSAGERHGSHHQQSADSSRHS 2668

Query: 243  -----HPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAA--QRRDPADTISEAAQRRD 295
                   +  + ++  R       S+     + +DT S +A  Q      +  E+A+ R 
Sbjct: 2669 GIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRS 2728

Query: 296  --------------PADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMSE 341
                               SE++       T      R + A   S  +  +D  DT+  
Sbjct: 2729 GETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTI-- 2786

Query: 342  AVQRRHPADTMS--EAVQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRD 399
               R HP  +    +     H  D+   +        +   +   R  + + S +   R+
Sbjct: 2787 ---RGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRN 2843

Query: 400  ---PADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAAQRR----DPADTMSEAAQRRDP 452
                 D    +  R H A T ++ ++        SE ++R           S++    + 
Sbjct: 2844 EEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSED 2903

Query: 453  ADTMSEAAQRRHPADTTSEAVQ-RRHPADPMSEAAQRRDLADTMSEAAQRRDPEDTMSEA 511
            ++  S +A R H      +     RHP     + A     AD+  ++  R     +  +A
Sbjct: 2904 SERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQA 2963

Query: 512  AQRRDPADAMSEAAQR 527
            A   +   A S A +R
Sbjct: 2964 ASSHE--QARSSAGER 2977



 Score = 49.3 bits (116), Expect = 9e-06
 Identities = 97/548 (17%), Positives = 173/548 (31%), Gaps = 64/548 (11%)

Query: 8    RHPADTMSEAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRRHPADTMS 67
            RH A    +   R HP  +        H            H + TTS+         + S
Sbjct: 505  RHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGS 564

Query: 68   EAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQ--RR 125
             +A R+   +  S         D    +  R H A + +++ +        S   +  R 
Sbjct: 565  RSASRQTRNEEQS--------GDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRN 616

Query: 126  HPADTMSEAAQRRHPADT--MSEAVQRRHPADTMSEAVQRRDPADTMSEAVQRRHPADTM 183
              +    ++  + H  D+   S +  R H         Q RD +         RHP    
Sbjct: 617  QGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQE---QSRDGS---------RHPRSHH 664

Query: 184  SEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRH 243
             + A   H AD+  ++  R     +  +AA   + A   S A +R      +  A   RH
Sbjct: 665  EDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQAR--SSAGERHGSRHQLQSADSSRH 722

Query: 244  PADTMSEAAQR-RDPADTISEAAQRRD------PADTMS----------EAAQRRDPADT 286
                  +A+   RD     S  +Q  D       +DT S          + + +    D 
Sbjct: 723  SGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDR 782

Query: 287  ISEAAQR------RDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMS 340
              E ++R      +      SE++       T        + A   S  +  +D  DT+ 
Sbjct: 783  SGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTI- 841

Query: 341  EAVQRRHPADTMSEAVQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQR--- 397
                R HP  +        H              + T S+         + S +A R   
Sbjct: 842  ----RGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTR 897

Query: 398  --RDPADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAAQ--RRDPADTM--SEAAQRRD 451
                  D    +  R H A + ++ ++        SE ++  RR  +     S++    +
Sbjct: 898  NEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSE 957

Query: 452  PADTMSEAAQRRHPADTTSEAVQ-RRHPADPMSEAAQRRDLADTMSEAAQRRDPEDTMSE 510
             ++  S +A R H      ++    RHP     + A     AD+  ++        +  +
Sbjct: 958  DSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQ 1017

Query: 511  AAQRRDPA 518
            AA   + A
Sbjct: 1018 AASSHEQA 1025



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 91/494 (18%), Positives = 155/494 (31%), Gaps = 44/494 (8%)

Query: 15  SEAVQRRHPADTMSEAAQ-RRHPADTTSEAAQRRHPADTTSEPVQRRHPADTMSEAAQRR 73
           S +  R H      ++    RHP     + A   H AD++ +   R     +  + A   
Sbjct: 314 SGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSH 373

Query: 74  HPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSE 133
             A     +   RH +     A   RH A    +A      +  +S+   R       S+
Sbjct: 374 EQA---RSSPGERHGSGHQQSADSSRHSATGRGQA------SSAVSDRGHRGSSGSQASD 424

Query: 134 AAQRRHPADTMSEA-------VQRRHPADTMSEAVQRRDPADTMSEAVQRRHPADTMSEA 186
           +      +DT S +        Q+ H   T   + +R   + +    V      D    +
Sbjct: 425 SEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPD----S 480

Query: 187 AQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPAD 246
           A  R    T        + A   S  +  ++  DTI     R  P  +        H   
Sbjct: 481 AHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTI-----RGHPGSSRGGRQGSHHEQS 535

Query: 247 TMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPA---DTMSEA 303
                      + T S+         + S +A R+   +  S    R   +   +  S+A
Sbjct: 536 VNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQA 595

Query: 304 AQRRHPADTMSEAAQRRDPADTMSEAAQRRD------PADTMSEAVQRRHPADTMSEAVQ 357
              RH      +++  R   +  S  +Q  D       ++  S +  R H      ++  
Sbjct: 596 DSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRD 655

Query: 358 -RRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADT 416
             RHP     + A     AD+  ++  R     +  +AA   + A   S A +R      
Sbjct: 656 GSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQA--RSSAGERHGSRHQ 713

Query: 417 MSEAAQRRHPADTMSEAAQR-RDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEAVQR 475
           +  A   RH      +A+   RD     S  +Q  D     SE         + S   Q 
Sbjct: 714 LQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATD-----SEGHSEDSDTQSVSGHGQA 768

Query: 476 RHPADPMSEAAQRR 489
            H      E+A+ R
Sbjct: 769 GHHQQSHQESARDR 782



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 69/383 (18%), Positives = 127/383 (33%), Gaps = 41/383 (10%)

Query: 177 RHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTI---SEAAQRRDPAD 233
           RHP     + A   H AD+  ++  R     +  + A   + A +       +  +  AD
Sbjct: 334 RHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSAD 393

Query: 234 TMSEAAQRRHPADT-MSEAAQRRDPADTISEAAQRRDPADTMSEAA-------QRRDPAD 285
           +   +A  R  A + +S+   R       S++    + +DT S +        Q+     
Sbjct: 394 SSRHSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQES 453

Query: 286 TISEAAQRRDPADT---------MSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPA 336
           T   + +R   + +           ++A  R    T        + A   S  +  ++  
Sbjct: 454 TRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQ 513

Query: 337 DTMSEAVQRRHPADTMSEAVQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQ 396
           DT+     R HP  +        H              + T S+         + S +A 
Sbjct: 514 DTI-----RGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSAS 568

Query: 397 RR-----DPADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRD 451
           R+        D    +  R H A   S+A   RH      +++  R   +  S  +Q  D
Sbjct: 569 RQTRNEEQSGDGTRHSGSRHHEAS--SQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSD 626

Query: 452 ------PADTMSEAAQRRHPADTTSEAVQ-RRHPADPMSEAAQRRDLADTMSEAAQRRDP 504
                  ++  S +A R H      ++    RHP     + A     AD+  ++  R   
Sbjct: 627 SQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQ 686

Query: 505 EDTMSEAAQRRDPADAMSEAAQR 527
             +  +AA   +   A S A +R
Sbjct: 687 NSSSGQAASSHE--QARSSAGER 707



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 82/486 (16%), Positives = 156/486 (32%), Gaps = 49/486 (10%)

Query: 8    RHPADTMSEAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRRHPADTMS 67
            RHP     +     H AD+  ++  R   + +  +AA     A   S   +R      + 
Sbjct: 1955 RHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQA--RSSAGERHGSHHQLQ 2012

Query: 68   EAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQ-RRH 126
             A   RH        +     +  + ++  R +     S++      +DT S +AQ +  
Sbjct: 2013 SADSSRH------SGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAG 2066

Query: 127  PADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAVQRRDPADTMSEAVQRRHPADTMSEA 186
            P     + + R    ++   +    +   T  ++      +   +   Q  H       +
Sbjct: 2067 PHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSS 2126

Query: 187  AQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPAD 246
               RH A    +   R  P            P+    + + +    D    +    H + 
Sbjct: 2127 ---RHSASQEGQDTIRGHPG-----------PSRGGRQGSHQEQSVDRSGHSGS--HHSH 2170

Query: 247  TMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRDPA---DTISEAAQRRDPADTMSEA 303
            T S+         + S +A R+      S    R   +   +  S A   R       ++
Sbjct: 2171 TTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQS 2230

Query: 304  AQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAVQ-RRHPA 362
            +  R      S  +Q  D ++  SE ++RR      S +  R H      ++    RHP 
Sbjct: 2231 SGPRTSRPRGSSVSQDSD-SEGHSEDSERR------SGSASRNHHGSAQEQSRDGSRHPR 2283

Query: 363  DTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQ 422
                + A     A++  ++        +  +AA   + A     +A  RH +     A  
Sbjct: 2284 SHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQA---RSSAGERHGSHHQQSADS 2340

Query: 423  RRHPADTMSEAAQR-RDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEAVQRRHPADP 481
             RH      +A+   RD     S  +Q  D            H  D+ +++V     A P
Sbjct: 2341 SRHSGIGHGQASSAVRDSGHRGSSGSQASD---------SEGHSEDSDTQSVSAHGQAGP 2391

Query: 482  MSEAAQ 487
              ++ Q
Sbjct: 2392 HQQSHQ 2397


>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
          Length = 841

 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 75/406 (18%), Positives = 145/406 (35%), Gaps = 18/406 (4%)

Query: 13  TMSEAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRRHPADTMSEAAQR 72
           +++ +V R  PA    E  +RR P    S A  RR P    + PVQ++   D   E  ++
Sbjct: 374 SVTRSVHRCAPA---GERGERRKPNAGGSPAPVRRRPE---ASPVQKKEKKDKEREN-EK 426

Query: 73  RHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMS---EAAQRRHPAD 129
              A     ++++R        A      A  +S   + R  + + S    A+    P  
Sbjct: 427 EKSALARERSLKKRQSLPASPRARLSASTASELSPKSKARPSSPSTSWHRPASPCPSPGP 486

Query: 130 TMSEAAQRRHPADTMSEAVQRRHPADTMSEAVQRRDPADTMSEAVQRRHPADTMSEAAQR 189
             +   +   P  T +    R    +   E+     P D      +  +  ++ + A+  
Sbjct: 487 GHTLPPKPPSPRGTTASPKGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPA 546

Query: 190 RHPADTMSEAAQRRD--PADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADT 247
             PA + + A  +++  PA+T ++AA    P          +  A T       R  A+ 
Sbjct: 547 PSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEK 606

Query: 248 MSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRR 307
             +A ++R+  +        RD      + A+  +        A+RR+  +   +A   +
Sbjct: 607 RRQAREQREREEQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQAEQ 666

Query: 308 HPADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAVQRRHPADTMSE 367
              + + +  +  +         QR +      +  Q R       E + +R     +SE
Sbjct: 667 EEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRTRKSEVSE 726

Query: 368 AAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRHP 413
             Q++D     S+ A     +    +A + R P     EA Q+  P
Sbjct: 727 TKQKQD-----SKEANANGSSPEPVKAVEARSPG-LQKEAVQKEEP 766



 Score = 52.8 bits (125), Expect = 8e-07
 Identities = 81/413 (19%), Positives = 150/413 (36%), Gaps = 34/413 (8%)

Query: 126 HPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAVQRRDPADTMSEAVQRRHPADTMSE 185
           H      E  +RR P    S A  RR P    +  VQ+++  D   E  ++   A     
Sbjct: 380 HRCAPAGERGERRKPNAGGSPAPVRRRPE---ASPVQKKEKKDKEREN-EKEKSALARER 435

Query: 186 AAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPA 245
           + ++R    ++  + + R  A T SE + +     +    +  R  +   S       P 
Sbjct: 436 SLKKRQ---SLPASPRARLSASTASELSPKSKARPSSPSTSWHRPASPCPSPGPGHTLPP 492

Query: 246 DTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQ 305
              S       P   +    +R++ A     AA   D + +   A+  ++ A   S A  
Sbjct: 493 KPPSPRGTTASPKGRV----RRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPS 548

Query: 306 RRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAVQRRHPADTM 365
              P+ T +   + + PA+T ++AA    P          +  A T       R  A+  
Sbjct: 549 PA-PSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKR 607

Query: 366 SEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRH 425
            +A ++R+      E  +RR  A+   +   R +     +EA   R       E  + R 
Sbjct: 608 RQAREQRE-----REEQERRLQAER--DKRMREEQLAREAEARAEREAEARRREEQEARE 660

Query: 426 PADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEAVQRRHPADPMSEA 485
            A    E  +R       +EA  R +      E  + +H      E  +RR   + + + 
Sbjct: 661 KAQAEQEEQERLQKQKEEAEARSREEAERQRLE--REKHFQQQEQERQERRKRLEEIMKR 718

Query: 486 AQRRDLADTMSEAAQRRDPEDTMS--------EAAQRRDPADAMSEAAQRRDP 530
            ++ ++    SE  Q++D ++  +        +A + R P     EA Q+ +P
Sbjct: 719 TRKSEV----SETKQKQDSKEANANGSSPEPVKAVEARSPG-LQKEAVQKEEP 766



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 65/368 (17%), Positives = 127/368 (34%), Gaps = 15/368 (4%)

Query: 169 TMSEAVQRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTISEAAQR 228
           +++ +V R  PA    E  +RR P    S A  RR P  +  +  +++D      E    
Sbjct: 374 SVTRSVHRCAPA---GERGERRKPNAGGSPAPVRRRPEASPVQKKEKKD-----KERENE 425

Query: 229 RDPADTMSEAAQRRHPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRDPADTIS 288
           ++ +    E + ++    ++  + + R  A T SE + +     +    +  R  +   S
Sbjct: 426 KEKSALARERSLKKR--QSLPASPRARLSASTASELSPKSKARPSSPSTSWHRPASPCPS 483

Query: 289 EAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAVQRRHP 348
                  P    S       P   +    +R++ A     AA   D + +   A   +  
Sbjct: 484 PGPGHTLPPKPPSPRGTTASPKGRV----RRKEEAKESPSAAGPEDKSQSKRRASNEKES 539

Query: 349 ADTMSEAVQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAA 408
           A   S A     P+ T +   + + PA+T ++AA    P          +  A T     
Sbjct: 540 AAPASPAPSPA-PSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREE 598

Query: 409 QRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAAQRRHPADT 468
             R  A+   +A ++R   +        RD      + A+  +        A+RR   + 
Sbjct: 599 ATRLLAEKRRQAREQREREEQERRLQAERDKRMREEQLAREAEARAEREAEARRREEQEA 658

Query: 469 TSEAVQRRHPADPMSEAAQRRDLADTMSEAAQRRDPEDTMSEAAQRRDPADAMSEAAQRR 528
             +A   +   + + +  +  +         QR + E    +  Q R       E   +R
Sbjct: 659 REKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKR 718

Query: 529 DPEDTMSE 536
             +  +SE
Sbjct: 719 TRKSEVSE 726


>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
          Length = 1564

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 97/526 (18%), Positives = 177/526 (33%), Gaps = 41/526 (7%)

Query: 32  QRRHPADTTSEAAQRRHPADTTSEPVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADT 91
           ++R    +TS A Q   P  +      R H + + S ++ +RH      +         T
Sbjct: 309 EKRDKPRSTSPAGQHHSPISS------RHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRT 362

Query: 92  MSEAAQRR---HPADTMSEAVQRRHPADTMSEAAQR-RHPADTMSEAAQRRHPA------ 141
           ++   +R    +P+ ++S   +++ P    S   ++ RH  +  S++  RRH        
Sbjct: 363 LTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRG 422

Query: 142 --DTMSEAVQRRHPADTMSEAVQRRDPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEA 199
             D   ++ + R      S +   RD  +   +   RR   DT      RR   D+  + 
Sbjct: 423 KRDREKDSREEREYEQDQSSSRDHRDDREPR-DGRDRRDARDTRD----RRELRDSR-DM 476

Query: 200 AQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPAD 259
              R+  D   +  + RDP D+ S     RD  D      +  H  +       R    +
Sbjct: 477 RDSREMRDYSRDTKESRDPRDSRST----RDAHDYRDREGRDTHRKEDTYPEESRSYGRN 532

Query: 260 TISEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQR 319
            + E + R +  +     ++     D +  +  R            R    D+ S  +  
Sbjct: 533 HLREESSRTEIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGSQIDSHSSNSNY 592

Query: 320 RDPADTMSEAAQR-----RDPADTMSEA-VQRRHPADTMSEAVQRRHPADTMSEAAQRRD 373
            D  +T S   +R     RD  D   ++  +RRH      +  +R     +      R D
Sbjct: 593 HDSWETRSSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRND 652

Query: 374 PADTMSEAAQRR--HPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRHPADTMS 431
             +      +RR     D   E A+ RD         +R    +   E  + R      +
Sbjct: 653 ELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERA 712

Query: 432 EAAQRRDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEAVQRRHPADPMSEAAQRRD- 490
              +R    +   E  + RD         +R    +   E  +R    +   E  + R+ 
Sbjct: 713 REREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERER 772

Query: 491 ----LADTMSEAAQRRDPEDTMSEAAQRRDPADAMSEAAQRRDPED 532
                 +   E  ++RD ED       RR+  + + E    RD  D
Sbjct: 773 ERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHD 818



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 95/518 (18%), Positives = 167/518 (32%), Gaps = 42/518 (8%)

Query: 7   RRHPADTMS-EAVQRRHPAD----TMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRRH 61
           R H + + S  ++QR  P+     T S + QR         A+   +P+ + S P +++ 
Sbjct: 330 RHHSSSSQSGSSIQRHSPSPRRKRTPSPSYQRTLTPPLRRSASP--YPSHSLSSPQRKQS 387

Query: 62  PADTMSEAAQR-RHPADTMSEAVQRRHPA--DTMS----EAAQRRHPADTMSEAVQRRHP 114
           P    S   ++ RH  +  S++  RRH    DT      E   R        ++  R H 
Sbjct: 388 PPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSREEREYEQDQSSSRDHR 447

Query: 115 ADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAVQRRDPADTMS--- 171
            D      + R  A    +  + R   D       R +  DT     + RDP D+ S   
Sbjct: 448 DDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRDTK----ESRDPRDSRSTRD 503

Query: 172 -------EAVQRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTISE 224
                  E        DT  E + R +  + + E + R +  +     ++     D +  
Sbjct: 504 AHDYRDREGRDTHRKEDTYPEES-RSYGRNHLREESSRTEIRNESRNESRSEIRNDRMGR 562

Query: 225 AAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTISEAAQR-----RDPADTMSEAAQ 279
           +  R            R    D+ S  +   D  +T S   +R     RD  D   +++ 
Sbjct: 563 SRGRVPELPEKGSRGSRGSQIDSHSSNSNYHDSWETRSSYPERDRYPERDNRDQARDSSF 622

Query: 280 RRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPA---DTMSEAAQRRDPA 336
            R   +      + RD   +     Q R+      E  + R      D   E A+ RD  
Sbjct: 623 ERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRE 682

Query: 337 DTMSEAVQRRHPADTMSEA-----VQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTM 391
                  +R    +   E      ++R    +   E  + RD          R    +  
Sbjct: 683 RERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERE 742

Query: 392 SEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRD 451
            +  + R+      E  + R          +R    +   E  ++RD  D       RR+
Sbjct: 743 RDREKEREREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRRE 802

Query: 452 PADTMSEAAQRRHPADTTSEAVQRRHPADPMSEAAQRR 489
             + + E    R   D      + R+   P    + +R
Sbjct: 803 KREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKR 840



 Score = 29.3 bits (64), Expect = 9.5
 Identities = 37/181 (20%), Positives = 62/181 (34%), Gaps = 10/181 (5%)

Query: 175 QRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADT 234
           +R    D   E  + R          +R    +   E A+ R+  +   E  + RD    
Sbjct: 674 ERARERDRERERDRERERERERERDREREKERELERERARERE-REREKERDRERDRDRD 732

Query: 235 MSEAAQRRHPADTMSEAAQRRDPADTISEAAQRRD-PADTMSEAAQRRDPADTISEAAQR 293
                +R    D   E  + R+  +   E  + R+   +   E A+ RD      E  ++
Sbjct: 733 HDRERERERERDREKEREREREERERERERERERERERERERERARERD-----KERERQ 787

Query: 294 RDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRD---PADTMSEAVQRRHPAD 350
           RD  D       RR   + + E    RD  D      + R+   P+   S   +R H  D
Sbjct: 788 RDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPD 847

Query: 351 T 351
           +
Sbjct: 848 S 848


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 101/549 (18%), Positives = 189/549 (34%), Gaps = 29/549 (5%)

Query: 3   EAVQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRRHP 62
           + ++R    +   +   RR       +  +RR   +   E  +RR   +   E  Q R  
Sbjct: 284 QELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQ-QLRRE 342

Query: 63  ADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRHP--ADTMSE 120
            +   E   RR   +   E   RR   +   E   RR       + ++R      +    
Sbjct: 343 QEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLR 402

Query: 121 AAQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAVQRRDPADTMSEAVQRRHPA 180
             Q+      +    Q R       E  + RH      E  ++R   +        +   
Sbjct: 403 REQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREE 462

Query: 181 DTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQ 240
           +T     +RR       +  +RR+    + E  +RR+  +   E   RR+  +   +  +
Sbjct: 463 ETERHEQERRKQQLKRDQEEERRERWLKLEE-EERREQQER-REQQLRREQEERREQRLK 520

Query: 241 RRHPADTM-----SEAAQRRDPADTISEAAQRRDPADTMSEAAQRRDPADTISEAAQRRD 295
           R+   + +     SE   RR+  +   +  +R +      E  ++R       E  +RRD
Sbjct: 521 RQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQR----LKREQEERRD 576

Query: 296 PADTMSEAAQRRHPADTMSEAAQRRDPADTMS--EAAQRRDPADTMSEAVQRRHPADTMS 353
                 E  +++       E  ++R   + +   E  +RR+      E  + R      S
Sbjct: 577 QLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKS 636

Query: 354 EAVQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRHP 413
           E  + R       E  +RR+      E  +R           +RR+    ++E  Q +  
Sbjct: 637 EEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERRE--QELAEEEQEQAR 694

Query: 414 ADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEAV 473
               S   + +   ++ ++A Q +  +    +  QRR       E  +RR  ++   +  
Sbjct: 695 ERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQE---QEEKRRRRESELQWQEE 751

Query: 474 QRRHPADPMSEAAQRRDL-----ADTMSE-AAQRRDPEDTMSEAAQRRDPADAMSEAAQR 527
           +R H      E  QRRD      A+  SE   QR      + E  +R+  A+   +  QR
Sbjct: 752 ERAH--RQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQR 809

Query: 528 RDPEDTMSE 536
             PE+   E
Sbjct: 810 FLPEEEEKE 818



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 78/491 (15%), Positives = 160/491 (32%), Gaps = 35/491 (7%)

Query: 55  EPVQRRHPADTMSEAAQRRHPADTMSEAVQ--------RRHPADTMSEAAQRRHPADTMS 106
           E V R+       E  QR+       E ++        R    +   +   RR       
Sbjct: 250 ETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRK 309

Query: 107 EAVQRRHPADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAVQRRDP 166
           +  +RR   +   E  +RR   +   E   RR   +   + ++R    +   + ++R   
Sbjct: 310 QEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQE 369

Query: 167 ADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTISEAA 226
            +   + ++R      +    Q R       E   RR+      +  +R        +  
Sbjct: 370 EERREQQLRRE---QQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 426

Query: 227 QRRDPADTMSEAAQRRHPADTMSEAAQRRD----PADTISEAAQRRDPADTMSEAAQRRD 282
           + ++      +  Q R       E  +RRD      +T     +RR       +  +RR+
Sbjct: 427 REQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRE 486

Query: 283 PADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTM-----SEAAQRRDPAD 337
               + E  +R        E   RR   +   +  +R++  + +     SE   RR+  +
Sbjct: 487 RWLKLEEEERREQ--QERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEE 544

Query: 338 TMSEAVQRRHPADTMSEAVQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQR 397
              + ++R    +      Q R       E  +RRD      E  +++       E  ++
Sbjct: 545 RREQLLKR----EEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQ 600

Query: 398 RDPADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMS 457
           R       E  +R    +   +  +R  P +   +   + +  +   +   RR+  +   
Sbjct: 601 R----LKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERRE 656

Query: 458 EAAQRRHPADTTSEAVQRRHPADPMSEAAQRRDLADTMSEAAQRRDPEDTMSEAAQRRDP 517
           +  +R    +   + ++R H      E  + ++LA+   E A+ R          Q    
Sbjct: 657 QRLKREEEEERLEQRLKREH-----EEERREQELAEEEQEQARERIKSRIPKWQWQLESE 711

Query: 518 ADAMSEAAQRR 528
           ADA       R
Sbjct: 712 ADARQSKVYSR 722



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 49/271 (18%), Positives = 88/271 (32%), Gaps = 14/271 (5%)

Query: 272 DTMSEAAQRR-DPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAA 330
           D   E  QRR +P D   E    +       E  +     +  SE  +R +  D      
Sbjct: 112 DRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDE 171

Query: 331 QRRDPADTMSEAVQRRHPADTMSEAVQRRHPADTMSEAAQRRDPADTMSEAA-----QRR 385
           +         E  +RR   + +              E  +RR+  +   +       QRR
Sbjct: 172 ELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRR 231

Query: 386 HPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSE 445
              D + +  + ++      E   R+       E  QR+       E  ++ +  +   E
Sbjct: 232 ERQDRVFQEEEEKEWRKR--ETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRE 289

Query: 446 AAQRRDPADTMSEAAQRRHPADTTSEAVQRRHPADPMSEAAQRRDLADTMSEAAQRRDPE 505
             +       +    Q R   +      +RR   +   E  +RR+  +   E   RR+ E
Sbjct: 290 RQEEEQQQQRLRREQQLRRKQEE-----ERREQQEERREQQERREQQEERREQQLRREQE 344

Query: 506 DTMSEAAQRRDPADAMSEAAQRRDPEDTMSE 536
           +   E   RR+  +   E   RR+ E+   E
Sbjct: 345 E-RREQQLRREQEEERREQQLRREQEEERRE 374


>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
          Length = 4547

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 114/519 (21%), Positives = 204/519 (39%), Gaps = 51/519 (9%)

Query: 16   EAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQ------RRHPADTMSEA 69
            EA +R+         A R    +  ++  Q +  A+     VQ      R+   +  S  
Sbjct: 1462 EATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRV 1521

Query: 70   AQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPAD 129
                  A     A+Q        +E A+RR         V+R        E AQR   A+
Sbjct: 1522 KAEAEAAREKQRALQALEELRLQAEEAERR----LRQAEVERARQVQVALETAQRSAEAE 1577

Query: 130  TMSEAAQRRHPADTMSEAVQRRHPA-DTMSEAVQRRDPADTMSEAVQRRHPADTMSEAAQ 188
              S+ A        +  ++Q  H A   + E  +RR  A   +EA + R  A+   E  Q
Sbjct: 1578 LQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERR--AQQQAEAERAREEAERELERWQ 1635

Query: 189  RRHPADTMSEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTM 248
             +      +EA + R  A+   E AQ++  A   +EA ++++ A+     A+RR  A+  
Sbjct: 1636 LK-----ANEALRLRLQAE---EVAQQKSLAQ--AEAEKQKEEAE---REARRRGKAE-- 1680

Query: 249  SEAAQRRDPADTISEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRH 308
             +A ++R+ A+   E  ++          A  ++     +E  Q       + E   R  
Sbjct: 1681 EQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQ 1740

Query: 309  PADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAVQRRHPADTMSEA 368
                 + A Q+R   +  +E A+ R   + +  +  R   A+  S +   +      +EA
Sbjct: 1741 --REAAAATQKRQELE--AELAKVRAEMEVLLASKAR---AEEESRSTSEKSKQRLEAEA 1793

Query: 369  AQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRHPAD 428
             + R+ A+   EAA+ R  A+   EA ++R  A+   +AA++R  A+ +   A++     
Sbjct: 1794 GRFRELAE---EAARLRALAE---EAKRQRQLAE--EDAARQRAEAERV--LAEKLAAIG 1843

Query: 429  TMSEAAQRRDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEAVQRRHPADPMSEAAQR 488
              +      + A    EA   R       EA QRR   +  ++     H AD     AQ 
Sbjct: 1844 EATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQ-----HKADIEERLAQL 1898

Query: 489  RDLADTMSEAAQRRDPEDTMSEAAQRRDPADAMSEAAQR 527
            R  +D+  E  Q+   EDT+ +  Q  +   A+  + ++
Sbjct: 1899 RKASDSELE-RQKGLVEDTLRQRRQVEEEILALKASFEK 1936


>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
          Length = 4551

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 114/519 (21%), Positives = 204/519 (39%), Gaps = 51/519 (9%)

Query: 16   EAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQ------RRHPADTMSEA 69
            EA +R+         A R    +  ++  Q +  A+     VQ      R+   +  S  
Sbjct: 1466 EATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRV 1525

Query: 70   AQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPAD 129
                  A     A+Q        +E A+RR         V+R        E AQR   A+
Sbjct: 1526 KAEAEAAREKQRALQALEELRLQAEEAERR----LRQAEVERARQVQVALETAQRSAEAE 1581

Query: 130  TMSEAAQRRHPADTMSEAVQRRHPA-DTMSEAVQRRDPADTMSEAVQRRHPADTMSEAAQ 188
              S+ A        +  ++Q  H A   + E  +RR  A   +EA + R  A+   E  Q
Sbjct: 1582 LQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERR--AQQQAEAERAREEAERELERWQ 1639

Query: 189  RRHPADTMSEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTM 248
             +      +EA + R  A+   E AQ++  A   +EA ++++ A+     A+RR  A+  
Sbjct: 1640 LK-----ANEALRLRLQAE---EVAQQKSLAQ--AEAEKQKEEAE---REARRRGKAE-- 1684

Query: 249  SEAAQRRDPADTISEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRH 308
             +A ++R+ A+   E  ++          A  ++     +E  Q       + E   R  
Sbjct: 1685 EQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQ 1744

Query: 309  PADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAVQRRHPADTMSEA 368
                 + A Q+R   +  +E A+ R   + +  +  R   A+  S +   +      +EA
Sbjct: 1745 --REAAAATQKRQELE--AELAKVRAEMEVLLASKAR---AEEESRSTSEKSKQRLEAEA 1797

Query: 369  AQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRHPAD 428
             + R+ A+   EAA+ R  A+   EA ++R  A+   +AA++R  A+ +   A++     
Sbjct: 1798 GRFRELAE---EAARLRALAE---EAKRQRQLAE--EDAARQRAEAERV--LAEKLAAIG 1847

Query: 429  TMSEAAQRRDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEAVQRRHPADPMSEAAQR 488
              +      + A    EA   R       EA QRR   +  ++     H AD     AQ 
Sbjct: 1848 EATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQ-----HKADIEERLAQL 1902

Query: 489  RDLADTMSEAAQRRDPEDTMSEAAQRRDPADAMSEAAQR 527
            R  +D+  E  Q+   EDT+ +  Q  +   A+  + ++
Sbjct: 1903 RKASDSELE-RQKGLVEDTLRQRRQVEEEILALKASFEK 1940


>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
          Length = 4547

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 114/519 (21%), Positives = 204/519 (39%), Gaps = 51/519 (9%)

Query: 16   EAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQ------RRHPADTMSEA 69
            EA +R+         A R    +  ++  Q +  A+     VQ      R+   +  S  
Sbjct: 1462 EATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRV 1521

Query: 70   AQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPAD 129
                  A     A+Q        +E A+RR         V+R        E AQR   A+
Sbjct: 1522 KAEAEAAREKQRALQALEELRLQAEEAERR----LRQAEVERARQVQVALETAQRSAEAE 1577

Query: 130  TMSEAAQRRHPADTMSEAVQRRHPA-DTMSEAVQRRDPADTMSEAVQRRHPADTMSEAAQ 188
              S+ A        +  ++Q  H A   + E  +RR  A   +EA + R  A+   E  Q
Sbjct: 1578 LQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERR--AQQQAEAERAREEAERELERWQ 1635

Query: 189  RRHPADTMSEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTM 248
             +      +EA + R  A+   E AQ++  A   +EA ++++ A+     A+RR  A+  
Sbjct: 1636 LK-----ANEALRLRLQAE---EVAQQKSLAQ--AEAEKQKEEAE---REARRRGKAE-- 1680

Query: 249  SEAAQRRDPADTISEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRH 308
             +A ++R+ A+   E  ++          A  ++     +E  Q       + E   R  
Sbjct: 1681 EQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQ 1740

Query: 309  PADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAVQRRHPADTMSEA 368
                 + A Q+R   +  +E A+ R   + +  +  R   A+  S +   +      +EA
Sbjct: 1741 --REAAAATQKRQELE--AELAKVRAEMEVLLASKAR---AEEESRSTSEKSKQRLEAEA 1793

Query: 369  AQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRHPAD 428
             + R+ A+   EAA+ R  A+   EA ++R  A+   +AA++R  A+ +   A++     
Sbjct: 1794 GRFRELAE---EAARLRALAE---EAKRQRQLAE--EDAARQRAEAERV--LAEKLAAIG 1843

Query: 429  TMSEAAQRRDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEAVQRRHPADPMSEAAQR 488
              +      + A    EA   R       EA QRR   +  ++     H AD     AQ 
Sbjct: 1844 EATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQ-----HKADIEERLAQL 1898

Query: 489  RDLADTMSEAAQRRDPEDTMSEAAQRRDPADAMSEAAQR 527
            R  +D+  E  Q+   EDT+ +  Q  +   A+  + ++
Sbjct: 1899 RKASDSELE-RQKGLVEDTLRQRRQVEEEILALKASFEK 1936


>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
          Length = 4515

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 114/519 (21%), Positives = 204/519 (39%), Gaps = 51/519 (9%)

Query: 16   EAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQ------RRHPADTMSEA 69
            EA +R+         A R    +  ++  Q +  A+     VQ      R+   +  S  
Sbjct: 1430 EATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRV 1489

Query: 70   AQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPAD 129
                  A     A+Q        +E A+RR         V+R        E AQR   A+
Sbjct: 1490 KAEAEAAREKQRALQALEELRLQAEEAERR----LRQAEVERARQVQVALETAQRSAEAE 1545

Query: 130  TMSEAAQRRHPADTMSEAVQRRHPA-DTMSEAVQRRDPADTMSEAVQRRHPADTMSEAAQ 188
              S+ A        +  ++Q  H A   + E  +RR  A   +EA + R  A+   E  Q
Sbjct: 1546 LQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERR--AQQQAEAERAREEAERELERWQ 1603

Query: 189  RRHPADTMSEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTM 248
             +      +EA + R  A+   E AQ++  A   +EA ++++ A+     A+RR  A+  
Sbjct: 1604 LK-----ANEALRLRLQAE---EVAQQKSLAQ--AEAEKQKEEAE---REARRRGKAE-- 1648

Query: 249  SEAAQRRDPADTISEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRH 308
             +A ++R+ A+   E  ++          A  ++     +E  Q       + E   R  
Sbjct: 1649 EQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQ 1708

Query: 309  PADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAVQRRHPADTMSEA 368
                 + A Q+R   +  +E A+ R   + +  +  R   A+  S +   +      +EA
Sbjct: 1709 --REAAAATQKRQELE--AELAKVRAEMEVLLASKAR---AEEESRSTSEKSKQRLEAEA 1761

Query: 369  AQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRHPAD 428
             + R+ A+   EAA+ R  A+   EA ++R  A+   +AA++R  A+ +   A++     
Sbjct: 1762 GRFRELAE---EAARLRALAE---EAKRQRQLAE--EDAARQRAEAERV--LAEKLAAIG 1811

Query: 429  TMSEAAQRRDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEAVQRRHPADPMSEAAQR 488
              +      + A    EA   R       EA QRR   +  ++     H AD     AQ 
Sbjct: 1812 EATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQ-----HKADIEERLAQL 1866

Query: 489  RDLADTMSEAAQRRDPEDTMSEAAQRRDPADAMSEAAQR 527
            R  +D+  E  Q+   EDT+ +  Q  +   A+  + ++
Sbjct: 1867 RKASDSELE-RQKGLVEDTLRQRRQVEEEILALKASFEK 1904


>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
          Length = 4684

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 114/519 (21%), Positives = 204/519 (39%), Gaps = 51/519 (9%)

Query: 16   EAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQ------RRHPADTMSEA 69
            EA +R+         A R    +  ++  Q +  A+     VQ      R+   +  S  
Sbjct: 1599 EATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRV 1658

Query: 70   AQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPAD 129
                  A     A+Q        +E A+RR         V+R        E AQR   A+
Sbjct: 1659 KAEAEAAREKQRALQALEELRLQAEEAERR----LRQAEVERARQVQVALETAQRSAEAE 1714

Query: 130  TMSEAAQRRHPADTMSEAVQRRHPA-DTMSEAVQRRDPADTMSEAVQRRHPADTMSEAAQ 188
              S+ A        +  ++Q  H A   + E  +RR  A   +EA + R  A+   E  Q
Sbjct: 1715 LQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERR--AQQQAEAERAREEAERELERWQ 1772

Query: 189  RRHPADTMSEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTM 248
             +      +EA + R  A+   E AQ++  A   +EA ++++ A+     A+RR  A+  
Sbjct: 1773 LK-----ANEALRLRLQAE---EVAQQKSLAQ--AEAEKQKEEAE---REARRRGKAE-- 1817

Query: 249  SEAAQRRDPADTISEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRH 308
             +A ++R+ A+   E  ++          A  ++     +E  Q       + E   R  
Sbjct: 1818 EQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQ 1877

Query: 309  PADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAVQRRHPADTMSEA 368
                 + A Q+R   +  +E A+ R   + +  +  R   A+  S +   +      +EA
Sbjct: 1878 --REAAAATQKRQELE--AELAKVRAEMEVLLASKAR---AEEESRSTSEKSKQRLEAEA 1930

Query: 369  AQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRHPAD 428
             + R+ A+   EAA+ R  A+   EA ++R  A+   +AA++R  A+ +   A++     
Sbjct: 1931 GRFRELAE---EAARLRALAE---EAKRQRQLAE--EDAARQRAEAERV--LAEKLAAIG 1980

Query: 429  TMSEAAQRRDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEAVQRRHPADPMSEAAQR 488
              +      + A    EA   R       EA QRR   +  ++     H AD     AQ 
Sbjct: 1981 EATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQ-----HKADIEERLAQL 2035

Query: 489  RDLADTMSEAAQRRDPEDTMSEAAQRRDPADAMSEAAQR 527
            R  +D+  E  Q+   EDT+ +  Q  +   A+  + ++
Sbjct: 2036 RKASDSELE-RQKGLVEDTLRQRRQVEEEILALKASFEK 2073


>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
          Length = 4525

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 114/519 (21%), Positives = 204/519 (39%), Gaps = 51/519 (9%)

Query: 16   EAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQ------RRHPADTMSEA 69
            EA +R+         A R    +  ++  Q +  A+     VQ      R+   +  S  
Sbjct: 1440 EATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRV 1499

Query: 70   AQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPAD 129
                  A     A+Q        +E A+RR         V+R        E AQR   A+
Sbjct: 1500 KAEAEAAREKQRALQALEELRLQAEEAERR----LRQAEVERARQVQVALETAQRSAEAE 1555

Query: 130  TMSEAAQRRHPADTMSEAVQRRHPA-DTMSEAVQRRDPADTMSEAVQRRHPADTMSEAAQ 188
              S+ A        +  ++Q  H A   + E  +RR  A   +EA + R  A+   E  Q
Sbjct: 1556 LQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERR--AQQQAEAERAREEAERELERWQ 1613

Query: 189  RRHPADTMSEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTM 248
             +      +EA + R  A+   E AQ++  A   +EA ++++ A+     A+RR  A+  
Sbjct: 1614 LK-----ANEALRLRLQAE---EVAQQKSLAQ--AEAEKQKEEAE---REARRRGKAE-- 1658

Query: 249  SEAAQRRDPADTISEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRH 308
             +A ++R+ A+   E  ++          A  ++     +E  Q       + E   R  
Sbjct: 1659 EQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQ 1718

Query: 309  PADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAVQRRHPADTMSEA 368
                 + A Q+R   +  +E A+ R   + +  +  R   A+  S +   +      +EA
Sbjct: 1719 --REAAAATQKRQELE--AELAKVRAEMEVLLASKAR---AEEESRSTSEKSKQRLEAEA 1771

Query: 369  AQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRHPAD 428
             + R+ A+   EAA+ R  A+   EA ++R  A+   +AA++R  A+ +   A++     
Sbjct: 1772 GRFRELAE---EAARLRALAE---EAKRQRQLAE--EDAARQRAEAERV--LAEKLAAIG 1821

Query: 429  TMSEAAQRRDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEAVQRRHPADPMSEAAQR 488
              +      + A    EA   R       EA QRR   +  ++     H AD     AQ 
Sbjct: 1822 EATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQ-----HKADIEERLAQL 1876

Query: 489  RDLADTMSEAAQRRDPEDTMSEAAQRRDPADAMSEAAQR 527
            R  +D+  E  Q+   EDT+ +  Q  +   A+  + ++
Sbjct: 1877 RKASDSELE-RQKGLVEDTLRQRRQVEEEILALKASFEK 1914


>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
          Length = 4533

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 114/519 (21%), Positives = 204/519 (39%), Gaps = 51/519 (9%)

Query: 16   EAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQ------RRHPADTMSEA 69
            EA +R+         A R    +  ++  Q +  A+     VQ      R+   +  S  
Sbjct: 1448 EATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRV 1507

Query: 70   AQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPAD 129
                  A     A+Q        +E A+RR         V+R        E AQR   A+
Sbjct: 1508 KAEAEAAREKQRALQALEELRLQAEEAERR----LRQAEVERARQVQVALETAQRSAEAE 1563

Query: 130  TMSEAAQRRHPADTMSEAVQRRHPA-DTMSEAVQRRDPADTMSEAVQRRHPADTMSEAAQ 188
              S+ A        +  ++Q  H A   + E  +RR  A   +EA + R  A+   E  Q
Sbjct: 1564 LQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERR--AQQQAEAERAREEAERELERWQ 1621

Query: 189  RRHPADTMSEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTM 248
             +      +EA + R  A+   E AQ++  A   +EA ++++ A+     A+RR  A+  
Sbjct: 1622 LK-----ANEALRLRLQAE---EVAQQKSLAQ--AEAEKQKEEAE---REARRRGKAE-- 1666

Query: 249  SEAAQRRDPADTISEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRH 308
             +A ++R+ A+   E  ++          A  ++     +E  Q       + E   R  
Sbjct: 1667 EQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQ 1726

Query: 309  PADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAVQRRHPADTMSEA 368
                 + A Q+R   +  +E A+ R   + +  +  R   A+  S +   +      +EA
Sbjct: 1727 --REAAAATQKRQELE--AELAKVRAEMEVLLASKAR---AEEESRSTSEKSKQRLEAEA 1779

Query: 369  AQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRHPAD 428
             + R+ A+   EAA+ R  A+   EA ++R  A+   +AA++R  A+ +   A++     
Sbjct: 1780 GRFRELAE---EAARLRALAE---EAKRQRQLAE--EDAARQRAEAERV--LAEKLAAIG 1829

Query: 429  TMSEAAQRRDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEAVQRRHPADPMSEAAQR 488
              +      + A    EA   R       EA QRR   +  ++     H AD     AQ 
Sbjct: 1830 EATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQ-----HKADIEERLAQL 1884

Query: 489  RDLADTMSEAAQRRDPEDTMSEAAQRRDPADAMSEAAQR 527
            R  +D+  E  Q+   EDT+ +  Q  +   A+  + ++
Sbjct: 1885 RKASDSELE-RQKGLVEDTLRQRRQVEEEILALKASFEK 1922


>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
          Length = 4574

 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 114/519 (21%), Positives = 204/519 (39%), Gaps = 51/519 (9%)

Query: 16   EAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQ------RRHPADTMSEA 69
            EA +R+         A R    +  ++  Q +  A+     VQ      R+   +  S  
Sbjct: 1489 EATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRV 1548

Query: 70   AQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPAD 129
                  A     A+Q        +E A+RR         V+R        E AQR   A+
Sbjct: 1549 KAEAEAAREKQRALQALEELRLQAEEAERR----LRQAEVERARQVQVALETAQRSAEAE 1604

Query: 130  TMSEAAQRRHPADTMSEAVQRRHPA-DTMSEAVQRRDPADTMSEAVQRRHPADTMSEAAQ 188
              S+ A        +  ++Q  H A   + E  +RR  A   +EA + R  A+   E  Q
Sbjct: 1605 LQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERR--AQQQAEAERAREEAERELERWQ 1662

Query: 189  RRHPADTMSEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTM 248
             +      +EA + R  A+   E AQ++  A   +EA ++++ A+     A+RR  A+  
Sbjct: 1663 LK-----ANEALRLRLQAE---EVAQQKSLAQ--AEAEKQKEEAE---REARRRGKAE-- 1707

Query: 249  SEAAQRRDPADTISEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRH 308
             +A ++R+ A+   E  ++          A  ++     +E  Q       + E   R  
Sbjct: 1708 EQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQ 1767

Query: 309  PADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAVQRRHPADTMSEA 368
                 + A Q+R   +  +E A+ R   + +  +  R   A+  S +   +      +EA
Sbjct: 1768 --REAAAATQKRQELE--AELAKVRAEMEVLLASKAR---AEEESRSTSEKSKQRLEAEA 1820

Query: 369  AQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRHPAD 428
             + R+ A+   EAA+ R  A+   EA ++R  A+   +AA++R  A+ +   A++     
Sbjct: 1821 GRFRELAE---EAARLRALAE---EAKRQRQLAE--EDAARQRAEAERV--LAEKLAAIG 1870

Query: 429  TMSEAAQRRDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEAVQRRHPADPMSEAAQR 488
              +      + A    EA   R       EA QRR   +  ++     H AD     AQ 
Sbjct: 1871 EATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQ-----HKADIEERLAQL 1925

Query: 489  RDLADTMSEAAQRRDPEDTMSEAAQRRDPADAMSEAAQR 527
            R  +D+  E  Q+   EDT+ +  Q  +   A+  + ++
Sbjct: 1926 RKASDSELE-RQKGLVEDTLRQRRQVEEEILALKASFEK 1963


>gi|24308215 retrotransposon gag domain containing 1 [Homo sapiens]
          Length = 1388

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 101/473 (21%), Positives = 155/473 (32%), Gaps = 37/473 (7%)

Query: 1   MSEAVQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRR 60
           MS  ++R   +  MS        ++TMS   Q   PA  +    Q R P        Q R
Sbjct: 497 MSTPLRRAPTSGAMSTQPVTATASETMS-MPQLTVPASGSMSMLQMRAPVSEAMSMPQMR 555

Query: 61  HPADTMSEAAQRRH-PADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMS 119
             A  ++ AAQ +   +  MS  +     + + S    R   +  MS    R   +  +S
Sbjct: 556 TMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRSLASGALS 615

Query: 120 EAAQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAVQRRDPADTMSEAVQRRHP 179
           +       + TM           T SEA+      DT+S A+      DT S  +     
Sbjct: 616 KPLMTPKASGTMFTEKM----TTTASEAMPTLLMRDTVSGALSMPQMTDTASGGLSASLM 671

Query: 180 ADTMSEAAQRRHPADTMS-----EAAQRRDPADTMSEAAQRRDPADTISEAAQRRDP--- 231
            DT S A        T+S        + +DP    +   + +     +S+    +DP   
Sbjct: 672 RDTASGAMSTSQMTATVSGGMSMPLMRAQDPGVMPASLMRAKVSGKMLSQPMSTQDPGGM 731

Query: 232 -------------------ADTMSEAAQRRHPADTMSEAAQRRDPADTISEAAQRRDPAD 272
                              +D MS    R   ++TMS    R            R   + 
Sbjct: 732 SMSPMKSMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPLMRTSDPGERPSLLTRASSSG 791

Query: 273 TMSEAAQRRDPADTISEAAQRRDPA-DTMSEAAQRRHPADTMSEAAQRRDP-ADTMSEAA 330
            MS    R   +  I  A   R PA   MS        +  MS   Q + P +  MS   
Sbjct: 792 EMSLPLMRAPASGEI--ATPLRSPAYGAMSAPQMTATASGMMSSMPQVKAPISGAMSMPL 849

Query: 331 QRRDPADTMSEAVQRRHPADTMSEAVQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADT 390
            R   +  MS  + R   +   S +      +  M     R   +  +S    R   + T
Sbjct: 850 TRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPVRAPASGGVSSPLVRAPASGT 909

Query: 391 MSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTM 443
           MS   +R    +T+S    R   +  MS A      +  MS+   R   + TM
Sbjct: 910 MSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGMSKPLMRAPASGTM 962



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 105/493 (21%), Positives = 154/493 (31%), Gaps = 23/493 (4%)

Query: 20  RRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRRHPADTMSEAAQRRHPADTM 79
           +R  A        RR P             A  T    Q   PA       Q R P    
Sbjct: 489 KRATASGKMSTPLRRAPTSGAMSTQPVTATASETMSMPQLTVPASGSMSMLQMRAPVSEA 548

Query: 80  SEAVQRRHPADTMSEAAQ-RRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAAQRR 138
               Q R  A  ++ AAQ +   +  MS  +     + + S    R   +  MS    R 
Sbjct: 549 MSMPQMRTMASGLTSAAQMKAMTSGAMSTPLMTAQTSGSTSTLLMRDTASGVMSCPQMRS 608

Query: 139 HPADTMSEAVQRRHPADTMSEAVQRRDPADTMSEAVQRRHPADTMSEAAQRRHPADTMSE 198
             +  +S+ +     + TM           T SEA+      DT+S A       DT S 
Sbjct: 609 LASGALSKPLMTPKASGTMF----TEKMTTTASEAMPTLLMRDTVSGALSMPQMTDTASG 664

Query: 199 AAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQR-RDP 257
                   DT S A        T+S           MS    R      M  +  R +  
Sbjct: 665 GLSASLMRDTASGAMSTSQMTATVSGG---------MSMPLMRAQDPGVMPASLMRAKVS 715

Query: 258 ADTISEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAA 317
              +S+    +DP   MS +  +   + T          +D MS    R   ++TMS   
Sbjct: 716 GKMLSQPMSTQDPGG-MSMSPMK---SMTAGGMQMNSPTSDVMSTPTVRAWTSETMSTPL 771

Query: 318 QRRDPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAVQRRHPA-DTMSEAAQRRDPAD 376
            R            R   +  MS  + R   +  +  A   R PA   MS        + 
Sbjct: 772 MRTSDPGERPSLLTRASSSGEMSLPLMRAPASGEI--ATPLRSPAYGAMSAPQMTATASG 829

Query: 377 TMSEAAQRRHP-ADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAAQ 435
            MS   Q + P +  MS    R   +  MS    R   +   S +      +  M     
Sbjct: 830 MMSSMPQVKAPISGAMSMPLTRSTASGGMSMPLMRAPDSRVTSTSQMMPTASGDMCTLPV 889

Query: 436 RRDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEAVQRRHPADPMSEAAQRRDLADTM 495
           R   +  +S    R   + TMS   +R    +T S  + R   +  MS A     ++  M
Sbjct: 890 RAPASGGVSSPLVRAPASGTMSTPLRRPSACETVSTELMRASASGHMSTAQTTAMVSGGM 949

Query: 496 SEAAQRRDPEDTM 508
           S+   R     TM
Sbjct: 950 SKPLMRAPASGTM 962



 Score = 37.4 bits (85), Expect = 0.035
 Identities = 57/271 (21%), Positives = 91/271 (33%), Gaps = 12/271 (4%)

Query: 235 MSEAAQRRHPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRDPADTISEAAQRR 294
           MS        ++ MS        A  +S   +    A+ MS A     P+  +       
Sbjct: 307 MSSLLMSSPGSEVMSTPLLSVPDAGEMSTLPKPAPDAEAMSPALMTALPSGVMPTQTMPA 366

Query: 295 DPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAVQRRHPADTMSE 354
             +  MS  + +   ++ MS    R   +  MS    R   +  MS  +     +  MS 
Sbjct: 367 PGSGAMSPWSTQNVDSEMMSNPPVRATASGVMSAPPVRALDSGAMSTPLMGAPASGNMS- 425

Query: 355 AVQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRHPA 414
            +Q+  PA      +    P+  +    Q       MS  A R   A           P 
Sbjct: 426 TLQKTVPASGAMTTSLMTVPSSGVMSTEQ-------MSATASRVMSAQLTMAKTSGAMPT 478

Query: 415 DTMSEAAQ---RRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSE 471
            +M   A+   R   +  MS   +R   +  MS        ++TMS   Q   PA  +  
Sbjct: 479 GSMKAVAKQYKRATASGKMSTPLRRAPTSGAMSTQPVTATASETMS-MPQLTVPASGSMS 537

Query: 472 AVQRRHPADPMSEAAQRRDLADTMSEAAQRR 502
            +Q R P        Q R +A  ++ AAQ +
Sbjct: 538 MLQMRAPVSEAMSMPQMRTMASGLTSAAQMK 568


>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
          Length = 2400

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 90/478 (18%), Positives = 151/478 (31%), Gaps = 39/478 (8%)

Query: 88   PADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQ----RRHPADTMSEAAQRRH---- 139
            P  TM         A  + + +QR+    T  EAA+    + H   T +   Q       
Sbjct: 1672 PKATMGATRGPIKEAFDLQQILQRKRGEHTDGEAAEVAPGKTHTDPTSTRTVQGAEGGLG 1731

Query: 140  PADTMSEAVQRRHPADTMSEAVQRRDPADTMSEA---VQRRHPADTMSEAAQRRHPADTM 196
            P  +    V      +      + +DP    +E     Q R      SE +      +  
Sbjct: 1732 PGLSQGPGVDEGEDGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAE 1791

Query: 197  SEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMS----EAAQRRHPADTMSEAA 252
             E     +  +T  + +   D     + A   +DP  +      EA +    A   SE  
Sbjct: 1792 QEGEGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGV 1851

Query: 253  QRRDPADTISEAAQRRDPADTMSEAAQRRDPADTISE---------AAQRRDPADTMSEA 303
            +  +      EA     P     EA +    A   SE           Q         EA
Sbjct: 1852 EAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEA 1911

Query: 304  AQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAVQRRHPAD 363
             +   P     EA +     +  SE A+ ++  +   EA  +  P   + E+ +    A 
Sbjct: 1912 EKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQ 1971

Query: 364  TMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQR 423
              SE  +  +      EA     P    SE  +  +    M EA +   P     EA  +
Sbjct: 1972 PESEDVEALEVEVETQEAEGEAQPE---SEDVEAPEAEGEMQEAEEEAQPESDGVEAQPK 2028

Query: 424  RHPAD----------TMSEAAQRRDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEAV 473
                +          T  +A    D  +      + ++    + EA    HP     +A 
Sbjct: 2029 SEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQ 2088

Query: 474  QRRHPADPMSEAAQRRDLADTMSEAAQRRDPEDTMSEAAQRRDPADAMSEAAQRRDPE 531
            +    A P SE  +  + A+  ++ A+  +  +T  EA    +  +A  EA     PE
Sbjct: 2089 EAEGEAQPESEGVEAPE-AEGEAQKAEGIEAPETEGEAQPESEGIEA-PEAEGEAQPE 2144



 Score = 29.6 bits (65), Expect = 7.3
 Identities = 24/98 (24%), Positives = 35/98 (35%), Gaps = 5/98 (5%)

Query: 7   RRHPADTMSEAVQRRHPAD----TMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRRHP 62
           RR  A+T+S    R         T       R P  +T    +R  P++    P   RHP
Sbjct: 234 RRSEAETLSGLTSRNKNGSWGPKTKPSVIHSRSPPGSTPRLPERPGPSNPPVGPAPGRHP 293

Query: 63  ADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRH 100
            DT +++       D M + V+         E   R H
Sbjct: 294 QDTPAQSGP-LVAGDDMKKKVRMNEDGSLSVEMKVRFH 330


>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
           [Homo sapiens]
          Length = 918

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 64/366 (17%), Positives = 137/366 (37%), Gaps = 34/366 (9%)

Query: 162 QRRDPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADT 221
           Q   P +    A ++R     +SE  + +H  D   +  + + P+     +   R P  T
Sbjct: 436 QADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVR-PLRT 494

Query: 222 ISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRR 281
                QR     T + A +    +        R DP  +  E  ++R       E  +R+
Sbjct: 495 FLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDPKCSFVEKERQR------LENLRRK 548

Query: 282 DPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRR--DPADTM 339
           + A+ +       D    + E   +R   + + +  Q R+  + M E  +++       +
Sbjct: 549 EEAEQLRRQKVEEDKRRRLEEVKLKRE--ERLRKVLQARERVEQMKEEKKKQIEQKFAQI 606

Query: 340 SEAVQRRHPADTMSEAVQRRHPADTMSEAAQRRDPADT-------MSEAAQRRHPADTMS 392
            E  ++        E  +++  A  M E   RR   +          E  +RRH      
Sbjct: 607 DEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRH-----Q 661

Query: 393 EAAQRR--DPADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRR 450
           E  Q++  +  + + +AA+ +  A+   +  + +   +      +RR+         +RR
Sbjct: 662 ELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQ--------ERR 713

Query: 451 DPADTMSEAAQRRHPADTTSEA-VQRRHPADPMSEAAQRRDLADTMSEAAQRRDPEDTMS 509
           +    ++E  +RR      +E  +Q R  A  + +   +R+L +   +  Q+R  E  + 
Sbjct: 714 EQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQ 773

Query: 510 EAAQRR 515
           E  +++
Sbjct: 774 EEQEKK 779


>gi|21450645 tetratricopeptide repeat domain 16 [Homo sapiens]
          Length = 873

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 43/192 (22%), Positives = 91/192 (47%), Gaps = 9/192 (4%)

Query: 149 QRRHPADTMSEAVQRRDPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAAQRRDPADT 208
           QR+  + T     QRR+ + T +  + +R+ + T +  +QRR+ + T +   Q +  + T
Sbjct: 678 QRQSLSKTEPTQSQRRNSSKTKA-TIHKRNSSKTKATQSQRRNSSKTRATQGQGQSSSKT 736

Query: 209 MSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTISEAAQRR 268
            +   QR+  ++  +    R++P+ T +  + R+ P     +AA+ R    +  +A Q R
Sbjct: 737 EATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKV--KAARGRSWRPSKVDATQGR 794

Query: 269 D----PADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHP--ADTMSEAAQRRDP 322
                 + T +EA    + + + +E AQ +    + +E AQ +    + T S+A     P
Sbjct: 795 SRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQRSSKAEGAQGKSQGMSSTSSKAESTWGP 854

Query: 323 ADTMSEAAQRRD 334
           + ++S+    +D
Sbjct: 855 SPSLSKTEVDQD 866



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 40/200 (20%), Positives = 87/200 (43%), Gaps = 18/200 (9%)

Query: 309 PADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAVQRRHPADTMSEA 368
           P    +   QR+  + T    +QRR+ + T +  + +R+ + T +   QRR+ + T +  
Sbjct: 669 PRKIKATQGQRQSLSKTEPTQSQRRNSSKTKA-TIHKRNSSKTKATQSQRRNSSKTRATQ 727

Query: 369 AQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRHP-- 426
            Q +  + T +   QR+  ++  +    R++P+ T +  + R+ P    +   +   P  
Sbjct: 728 GQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRSWRPSK 787

Query: 427 -------------ADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAAQRRHP--ADTTSE 471
                        + T +EA    + + + +E AQ +    + +E AQ +    + T+S+
Sbjct: 788 VDATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQRSSKAEGAQGKSQGMSSTSSK 847

Query: 472 AVQRRHPADPMSEAAQRRDL 491
           A     P+  +S+    +DL
Sbjct: 848 AESTWGPSPSLSKTEVDQDL 867



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 47/203 (23%), Positives = 95/203 (46%), Gaps = 13/203 (6%)

Query: 23  PADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRRHPADTMSEAAQRRHPADTMSEA 82
           P    +   QR+  + T    +QRR+ + T +  + +R+ + T +  +QRR+ + T   A
Sbjct: 669 PRKIKATQGQRQSLSKTEPTQSQRRNSSKTKAT-IHKRNSSKTKATQSQRRNSSKT--RA 725

Query: 83  VQRRHPADTMSEAAQRRHPADTMSEAVQ--RRHPADTMSEAAQRRHPADTMSEAAQRRHP 140
            Q +  + + +EA Q +  + +  EA Q  R+ P+ T +  + R+ P     +AA+ R  
Sbjct: 726 TQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKV--KAARGRSW 783

Query: 141 ADTMSEAVQRRH----PADTMSEAVQRRDPADTMSEAVQRRHPADTMSEAAQRRHP--AD 194
             +  +A Q R      + T +EA    + + + +E  Q +    + +E AQ +    + 
Sbjct: 784 RPSKVDATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQRSSKAEGAQGKSQGMSS 843

Query: 195 TMSEAAQRRDPADTMSEAAQRRD 217
           T S+A     P+ ++S+    +D
Sbjct: 844 TSSKAESTWGPSPSLSKTEVDQD 866



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 47/194 (24%), Positives = 94/194 (48%), Gaps = 13/194 (6%)

Query: 84  QRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAAQRRHPADT 143
           QR+  + T    +QRR+ + T +  + +R+ + T +  +QRR+ + T   A Q +  + +
Sbjct: 678 QRQSLSKTEPTQSQRRNSSKTKA-TIHKRNSSKTKATQSQRRNSSKT--RATQGQGQSSS 734

Query: 144 MSEAVQRRHPADTMSEAVQ--RRDPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAAQ 201
            +EA Q +  + +  EA Q  R++P+ T +    R+ P     +AA+ R    +  +A Q
Sbjct: 735 KTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKV--KAARGRSWRPSKVDATQ 792

Query: 202 RRD----PADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHP--ADTMSEAAQRR 255
            R      + T +EA    + + + +E AQ +    + +E AQ +    + T S+A    
Sbjct: 793 GRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQRSSKAEGAQGKSQGMSSTSSKAESTW 852

Query: 256 DPADTISEAAQRRD 269
            P+ ++S+    +D
Sbjct: 853 GPSPSLSKTEVDQD 866



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 35/168 (20%), Positives = 76/168 (45%), Gaps = 3/168 (1%)

Query: 361 PADTMSEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEA 420
           P    +   QR+  + T    +QRR+ + T +    +R+ + T +  +QRR+ + T +  
Sbjct: 669 PRKIKATQGQRQSLSKTEPTQSQRRNSSKTKA-TIHKRNSSKTKATQSQRRNSSKTRATQ 727

Query: 421 AQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEAVQRRHPAD 480
            Q +  + T +   QR+  ++  +    R++P+ T +  + R+ P    +   +   P+ 
Sbjct: 728 GQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKVKAARGRSWRPSK 787

Query: 481 PMSEAAQRRDL--ADTMSEAAQRRDPEDTMSEAAQRRDPADAMSEAAQ 526
             +   + R L  + T +EA    +   + +E AQ +    + +E AQ
Sbjct: 788 VDATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQRSSKAEGAQ 835



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 46/188 (24%), Positives = 91/188 (48%), Gaps = 13/188 (6%)

Query: 292 QRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAVQRRHPADT 351
           QR+  + T    +QRR+ + T +    +R+ + T +  +QRR+ + T   A Q +  + +
Sbjct: 678 QRQSLSKTEPTQSQRRNSSKTKA-TIHKRNSSKTKATQSQRRNSSKT--RATQGQGQSSS 734

Query: 352 MSEAVQRRHPADTMSEAAQ--RRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQ 409
            +EA Q +  + +  EA Q  R++P+ T +  + R+ P     +AA+ R    +  +A Q
Sbjct: 735 KTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKV--KAARGRSWRPSKVDATQ 792

Query: 410 RRH----PADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDP--ADTMSEAAQRR 463
            R      + T +EA    + + + +E AQ +    + +E AQ +    + T S+A    
Sbjct: 793 GRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQRSSKAEGAQGKSQGMSSTSSKAESTW 852

Query: 464 HPADTTSE 471
            P+ + S+
Sbjct: 853 GPSPSLSK 860



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 41/195 (21%), Positives = 88/195 (45%), Gaps = 9/195 (4%)

Query: 192 PADTMSEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEA 251
           P    +   QR+  + T    +QRR+ + T      +R+ + T +  +QRR+ + T +  
Sbjct: 669 PRKIKATQGQRQSLSKTEPTQSQRRNSSKT-KATIHKRNSSKTKATQSQRRNSSKTRATQ 727

Query: 252 AQRRDPADTISEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPAD 311
            Q +  + T +   QR+  ++  +    R++P+ T +  + R+ P     +AA+ R    
Sbjct: 728 GQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRPRKV--KAARGRSWRP 785

Query: 312 TMSEAAQRRD----PADTMSEAAQRRDPADTMSEAVQRRHPADTMSEAVQRRHP--ADTM 365
           +  +A Q R      + T +EA    + + + +E  Q +    + +E  Q +    + T 
Sbjct: 786 SKVDATQGRSRGLLRSSTKTEAFYDSNWSLSKTEYAQGQGQRSSKAEGAQGKSQGMSSTS 845

Query: 366 SEAAQRRDPADTMSE 380
           S+A     P+ ++S+
Sbjct: 846 SKAESTWGPSPSLSK 860



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 38/173 (21%), Positives = 81/173 (46%), Gaps = 9/173 (5%)

Query: 6   QRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRRHPADT 65
           QRR+ + T +  + +R+ + T +  +QRR+ + T +   Q +  + T +   QR+  ++ 
Sbjct: 691 QRRNSSKTKA-TIHKRNSSKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQSSSEI 749

Query: 66  MSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRH----PADTMSEA 121
            +    R+ P+ T +    R+ P     +AA+ R    +  +A Q R      + T +EA
Sbjct: 750 EATQGPRQEPSKTKTTRSPRQRPRKV--KAARGRSWRPSKVDATQGRSRGLLRSSTKTEA 807

Query: 122 AQRRHPADTMSEAAQRRHPADTMSEAVQRRHP--ADTMSEAVQRRDPADTMSE 172
               + + + +E AQ +    + +E  Q +    + T S+A     P+ ++S+
Sbjct: 808 FYDSNWSLSKTEYAQGQGQRSSKAEGAQGKSQGMSSTSSKAESTWGPSPSLSK 860



 Score = 36.6 bits (83), Expect = 0.060
 Identities = 35/167 (20%), Positives = 76/167 (45%), Gaps = 8/167 (4%)

Query: 5   VQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRRHPAD 64
           + +R+ + T +   QRR+ + T +   Q +  + T +   QR+  ++  +    R+ P+ 
Sbjct: 702 IHKRNSSKTKATQSQRRNSSKTRATQGQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSK 761

Query: 65  TMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRH----PADTMSEAVQRRHPADTMSE 120
           T +  + R+ P     +A + R    +  +A Q R      + T +EA    + + + +E
Sbjct: 762 TKTTRSPRQRPRKV--KAARGRSWRPSKVDATQGRSRGLLRSSTKTEAFYDSNWSLSKTE 819

Query: 121 AAQRRHPADTMSEAAQRRHP--ADTMSEAVQRRHPADTMSEAVQRRD 165
            AQ +    + +E AQ +    + T S+A     P+ ++S+    +D
Sbjct: 820 YAQGQGQRSSKAEGAQGKSQGMSSTSSKAESTWGPSPSLSKTEVDQD 866



 Score = 33.5 bits (75), Expect = 0.50
 Identities = 20/95 (21%), Positives = 44/95 (46%), Gaps = 1/95 (1%)

Query: 439 PADTMSEAAQRRDPADTMSEAAQRRHPADTTSEAVQRRHPADPMSEAAQRRDLADTMSEA 498
           P    +   QR+  + T    +QRR+ + T +  + +R+ +   +  +QRR+ + T +  
Sbjct: 669 PRKIKATQGQRQSLSKTEPTQSQRRNSSKTKA-TIHKRNSSKTKATQSQRRNSSKTRATQ 727

Query: 499 AQRRDPEDTMSEAAQRRDPADAMSEAAQRRDPEDT 533
            Q +    T +   QR+  ++  +    R++P  T
Sbjct: 728 GQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKT 762



 Score = 32.7 bits (73), Expect = 0.86
 Identities = 21/105 (20%), Positives = 47/105 (44%), Gaps = 1/105 (0%)

Query: 426 PADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEAVQRRHPADPMSEA 485
           P    +   QR+  + T    +QRR+ + T +    +R+ + T +   QRR+ +   +  
Sbjct: 669 PRKIKATQGQRQSLSKTEPTQSQRRNSSKTKA-TIHKRNSSKTKATQSQRRNSSKTRATQ 727

Query: 486 AQRRDLADTMSEAAQRRDPEDTMSEAAQRRDPADAMSEAAQRRDP 530
            Q +  + T +   QR+   +  +    R++P+   +  + R+ P
Sbjct: 728 GQGQSSSKTEATQGQRQSSSEIEATQGPRQEPSKTKTTRSPRQRP 772


>gi|239754474 PREDICTED: similar to mucin [Homo sapiens]
          Length = 417

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 69/316 (21%), Positives = 103/316 (32%), Gaps = 26/316 (8%)

Query: 223 SEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTIS---EAAQRRDPADTMSEAAQ 279
           SE  Q  +   T     Q++          QRR    + S   + AQ R+     + AA 
Sbjct: 19  SEGDQWLENEKTKPLRPQQQPQCQPAGGTGQRRGSGSSPSADQQGAQDREEEAAAAPAAD 78

Query: 280 RRDPADTISEAAQRRDPADTMSEAAQRRH------PAD-TMSEAAQRRDPADTMSEAAQR 332
           ++   D   EAA    P  +     +R+       PA  T      R  P+     A  R
Sbjct: 79  QQRAQDREEEAAAAPVPTSSGHRTEKRKRLQLQCQPAGGTGQRRGSRSSPSADQQRAQDR 138

Query: 333 RDPADTMSEAVQRRHPADTMSEAVQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMS 392
            + A        R H  +       +R PA       QRR      S +A ++   D   
Sbjct: 139 EEEAAAAPVPTSRGHRTEKRKRQQPQRRPA---GGTGQRRGSGS--SPSADQQGAQDREE 193

Query: 393 EAAQRRDPADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDP 452
           EAA    P  +     ++R P     +  Q R    T      R  P+     A  R + 
Sbjct: 194 EAAAAPAPT-SRGHRTEKRKP-----QQPQCRPAGGTGQRRGSRSSPSADQQRAQDREEE 247

Query: 453 ADTMSEAAQRRHPADTTSEAVQRRHPADPMSEAAQRRDLADTMSEAAQRRDPEDTMSEAA 512
           A        R H  +       +R PA       QRR      S +A ++  +D   EAA
Sbjct: 248 AAAAPAPTSRGHRTEKRKPQQPQRRPA---GGTGQRR--GSGYSPSADQQGAQDREEEAA 302

Query: 513 QRRDPADAMSEAAQRR 528
               P  +     +R+
Sbjct: 303 AAPAPTSSGHRTEKRK 318



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 67/312 (21%), Positives = 96/312 (30%), Gaps = 27/312 (8%)

Query: 26  TMSEAAQRRHPADTTSEAAQRRHPADTTSEPVQRRHPADTMSEAAQRRHPADTMSEAVQR 85
           T      R  P+     A  R   A     P  R H  +       +R PA       QR
Sbjct: 118 TGQRRGSRSSPSADQQRAQDREEEAAAAPVPTSRGHRTEKRKRQQPQRRPAGGTG---QR 174

Query: 86  RHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAAQRRHPADTMS 145
           R      S +A ++   D   EA     P  +     ++R P     +  Q R    T  
Sbjct: 175 R--GSGSSPSADQQGAQDREEEAAAAPAPT-SRGHRTEKRKP-----QQPQCRPAGGTGQ 226

Query: 146 EAVQRRHPADTMSEAVQRRDPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAAQRRDP 205
               R  P+     A  R + A        R H  +       +R PA       QRR  
Sbjct: 227 RRGSRSSPSADQQRAQDREEEAAAAPAPTSRGHRTEKRKPQQPQRRPA---GGTGQRR-- 281

Query: 206 ADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRH---PADTMSEAAQRRDPADTIS 262
               S +A ++   D   EAA    P  +     +R+             QRR      S
Sbjct: 282 GSGYSPSADQQGAQDREEEAAAAPAPTSSGHRTEKRKRLQLQCQPAGGTGQRR--GSGCS 339

Query: 263 EAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDP 322
            +A ++   D   EAA    P  +     ++R P     +  QRR  A T         P
Sbjct: 340 SSANQQGAQDREEEAAAAPVPTSS-GHRTEKRKP-----QQPQRRPAAGTGQRRGSGSSP 393

Query: 323 ADTMSEAAQRRD 334
           +     A  R +
Sbjct: 394 SADQQRAQDREE 405


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 44/209 (21%), Positives = 86/209 (41%), Gaps = 26/209 (12%)

Query: 161  VQRRDPADTMSEAVQRR-HPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQ----- 214
            V+R++P DT S   Q+R  P+ ++ E        D  SE  + RD ADT  E A+     
Sbjct: 964  VKRKEPPDTTSSGDQKRLRPSTSVDE-------EDEESERERDRDMADTPCELAKRDPKG 1016

Query: 215  ---RRDPADTIS-EAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTIS---EAAQR 267
               RR PA  +  ++    D  +++SE  +     +   E  +  D  D  S   + ++ 
Sbjct: 1017 VGVRRRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESEN 1076

Query: 268  RDPADTMSEAAQR----RDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPA 323
             D    +SEA+++     D  +T+S    + +   +   +      + + S  +   D  
Sbjct: 1077 DDEDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEE 1136

Query: 324  DTMSEAAQRRDPADTM--SEAVQRRHPAD 350
            + ++   +  +  + M   E++    P D
Sbjct: 1137 EVVAREEEEEEEEEEMVAEESMASAGPED 1165



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 38/122 (31%), Positives = 55/122 (45%), Gaps = 15/122 (12%)

Query: 422  QRRHPADTMSEAAQRR-------DPADTMSEAAQRRDPADTMSEAAQRRHPADTTSEAVQ 474
            +R+ P DT S   Q+R       D  D  SE  + RD ADT  E A+R    D     V+
Sbjct: 965  KRKEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKR----DPKGVGVR 1020

Query: 475  RRHPADPMS-EAAQRRDLADTMSEAAQRRDPEDTMSEAAQRRDPADAMSE--AAQRRDPE 531
            RR PA P+  ++    D  +++SE  +  + E+   E  +  D  D  S+       D E
Sbjct: 1021 RR-PARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDE 1079

Query: 532  DT 533
            DT
Sbjct: 1080 DT 1081



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 46/202 (22%), Positives = 78/202 (38%), Gaps = 25/202 (12%)

Query: 356  VQRRHPADTMSEAAQRR-------DPADTMSEAAQRRHPADTMSEAAQ--------RRDP 400
            V+R+ P DT S   Q+R       D  D  SE  + R  ADT  E A+        RR P
Sbjct: 964  VKRKEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKRDPKGVGVRRRP 1023

Query: 401  ADTMS-EAAQRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSE--AAQRRDPADTMS 457
            A  +  ++       +++SE  +     +   E  +  D  D  S+       D  DT  
Sbjct: 1024 ARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTAL 1083

Query: 458  EAAQRRHPADTTSE----AVQRRHPADPMSEAAQRRDL-ADTMSEAAQRRDPEDTMSEAA 512
              A  +   D+  E     V  +  A   SE+++  +  + + S  +   D E+ ++   
Sbjct: 1084 SEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREE 1143

Query: 513  QRRDPADAM--SEAAQRRDPED 532
            +  +  + M   E+     PED
Sbjct: 1144 EEEEEEEEMVAEESMASAGPED 1165



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 28/109 (25%), Positives = 47/109 (43%), Gaps = 11/109 (10%)

Query: 435  QRRDPADTMSEAAQRR-------DPADTMSEAAQRRHPADTTSEAVQRRHPADPMSEAAQ 487
            +R++P DT S   Q+R       D  D  SE  + R  ADT  E  +R    DP     +
Sbjct: 965  KRKEPPDTTSSGDQKRLRPSTSVDEEDEESERERDRDMADTPCELAKR----DPKGVGVR 1020

Query: 488  RRDLADTMSEAAQRRDPEDTMSEAAQRRDPADAMSEAAQRRDPEDTMSE 536
            RR       ++    D ++++SE  +  +  +   E  +  D +D  S+
Sbjct: 1021 RRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSD 1069



 Score = 33.1 bits (74), Expect = 0.66
 Identities = 41/219 (18%), Positives = 77/219 (35%), Gaps = 31/219 (14%)

Query: 18   VQRRHPADTMSEAAQRR-HPADTTSEAAQRRHPADTTSEPVQRRHPADTMSEAAQRRHPA 76
            V+R+ P DT S   Q+R  P+ +  E        D  SE  + R  ADT  E A+R    
Sbjct: 964  VKRKEPPDTTSSGDQKRLRPSTSVDE-------EDEESERERDRDMADTPCELAKR---- 1012

Query: 77   DTMSEAVQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAAQ 136
            D     V+RR       ++       +++SE    +   +   EA +     D   + + 
Sbjct: 1013 DPKGVGVRRRPARPLELDSGGEEDEKESLSE---EQESTEEEEEAEEEEEEEDDDDDDSD 1069

Query: 137  RRHPADTMSEAVQRRHPADTMSEAVQRRDPADTMSEAVQRRHPADTMSEAAQRRHPADTM 196
             R  ++   E        DT       +D  D+  E        +T+S    +     + 
Sbjct: 1070 DRDESENDDE--------DTALSEASEKDEGDSDEE--------ETVSIVTSKAEATSSS 1113

Query: 197  SEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADTM 235
              +      + + S  +   D  + ++   +  +  + M
Sbjct: 1114 ESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEEEM 1152


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 85/513 (16%), Positives = 179/513 (34%), Gaps = 40/513 (7%)

Query: 42  EAAQRRHPADTTSEPVQR--RHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRR 99
           E    R   + +  P +R  R P+     +  RR    + S + + R  + + S A +++
Sbjct: 158 EKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKK 217

Query: 100 HPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSE 159
                + E      P+  + E + +   + +      +  P     E    ++ +    E
Sbjct: 218 EKTPELPE------PSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKN-SKKEKE 270

Query: 160 AVQRRDPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPA 219
             + R  + + S++  R           +RRH + + S + +RR P+     + +RR P 
Sbjct: 271 KEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRR-PSPRRRPSPRRRTPP 329

Query: 220 DTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQ 279
             +    + R      S +  RR    + S +      + + S +  ++ P  T S   +
Sbjct: 330 RRMPPPPRHR-----RSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRK 384

Query: 280 RRDPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRD-----PADTMSEAAQRRD 334
            R  + + S   +R  P+   +   + RH          R+      P  T  +  + + 
Sbjct: 385 TRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKG 444

Query: 335 PADTMSEAVQRRHPADTMSEAVQRRHPADTMSEAAQRRDPADTMSEAAQRRHPADTMSEA 394
                S +   +     +SE+ + +      +++ Q+R      ++ +     + + SE 
Sbjct: 445 TEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSED 504

Query: 395 AQ-RRDPADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPA 453
            + +R          +RRH     +  + R+   +T     +RR P+   +   +   PA
Sbjct: 505 ERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPA 564

Query: 454 D---------------TMSEAAQRRHPADTT-SEAVQRRHPADPMSEAAQRRDLADTMSE 497
                           T S   +RR P+    S  +QRR+   P  +             
Sbjct: 565 PPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRR 624

Query: 498 AAQRRDPEDTMSEAAQRRDPADAMSEAAQRRDP 530
           A+    P+  +S +     P    S   +RR P
Sbjct: 625 ASPSPPPKRRVSHSP---PPKQRSSPVTKRRSP 654



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 81/417 (19%), Positives = 141/417 (33%), Gaps = 30/417 (7%)

Query: 2   SEAVQRRHPADTMSEAVQRRHPADTMSEAAQRRHPADTTSEAAQRR-HPADTTSEPVQRR 60
           +++VQ+R      ++       + + SE  + +       E  +RR H    ++ P  R+
Sbjct: 476 ADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRK 535

Query: 61  HPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAAQRRHPAD-----TMSEAVQRRHPA 115
              +T     +RR P+       +RR          +RR P       T S   +RR P+
Sbjct: 536 RQKETSPRGRRRRSPS---PPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPS 592

Query: 116 D-TMSEAAQRRHPADTMSEAAQRRHPADTMSEAVQRRHPADTMSEAVQRRDPADTMSEAV 174
               S   QRR+          +R  A       +R  P+      V    P    S  V
Sbjct: 593 PRRYSPPIQRRY----SPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPV 648

Query: 175 QRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADTISEAAQRRDPADT 234
            +R      S+  +   P+ +  E A+   P    S + + R P  + S    RR  A +
Sbjct: 649 TKRRSPSLSSKHRKGSSPSRSTRE-ARSPQPNKRHSPSPRPRAPQTSSSPPPVRRG-ASS 706

Query: 235 MSEAAQRRHPADTMSEAAQRRDPADTISEAA-------QRRDPADTMS---EAAQRRDPA 284
             +  Q   P+        R      I +AA       +R   + ++S   E A ++ PA
Sbjct: 707 SPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPA 766

Query: 285 DTISEAAQRRDPADTMSEAAQ-RRHPADTMSEAAQRRDPADTMSEAAQRRDPADTMSEAV 343
                  Q + P+   S A   ++  + T S +  R    +   +  +++       +  
Sbjct: 767 P--PSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKK 824

Query: 344 QRRHPADTMSEAVQRRHPADTMSEAAQRRDPADTMSEAAQRRHP-ADTMSEAAQRRD 399
            ++H      +AV     A     A           E      P  +T SEA    D
Sbjct: 825 HKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKKETESEAEDNLD 881


>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
           [Homo sapiens]
          Length = 914

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 64/366 (17%), Positives = 136/366 (37%), Gaps = 38/366 (10%)

Query: 162 QRRDPADTMSEAVQRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRRDPADT 221
           Q   P +    A ++R     +SE  + +H  D   +  + + P+     +   R P  T
Sbjct: 436 QADGPREPPQSARRKRSYKQAVSELDEEQHLEDEELQPPRSKTPSSPCPASKVVR-PLRT 494

Query: 222 ISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTISEAAQRRDPADTMSEAAQRR 281
                QR     T + A     P   M    +R  P     +  +R+       E  +R+
Sbjct: 495 FLHTVQRNQMLMTPTSA-----PRSVMKSFIKRNTPLRMDPKEKERQ-----RLENLRRK 544

Query: 282 DPADTISEAAQRRDPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRR--DPADTM 339
           + A+ +       D    + E   +R   + + +  Q R+  + M E  +++       +
Sbjct: 545 EEAEQLRRQKVEEDKRRRLEEVKLKRE--ERLRKVLQARERVEQMKEEKKKQIEQKFAQI 602

Query: 340 SEAVQRRHPADTMSEAVQRRHPADTMSEAAQRRDPADT-------MSEAAQRRHPADTMS 392
            E  ++        E  +++  A  M E   RR   +          E  +RRH      
Sbjct: 603 DEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRH-----Q 657

Query: 393 EAAQRR--DPADTMSEAAQRRHPADTMSEAAQRRHPADTMSEAAQRRDPADTMSEAAQRR 450
           E  Q++  +  + + +AA+ +  A+   +  + +   +      +RR+         +RR
Sbjct: 658 ELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQ--------ERR 709

Query: 451 DPADTMSEAAQRRHPADTTSEA-VQRRHPADPMSEAAQRRDLADTMSEAAQRRDPEDTMS 509
           +    ++E  +RR      +E  +Q R  A  + +   +R+L +   +  Q+R  E  + 
Sbjct: 710 EQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQ 769

Query: 510 EAAQRR 515
           E  +++
Sbjct: 770 EEQEKK 775


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.115    0.314 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,748,068
Number of Sequences: 37866
Number of extensions: 755583
Number of successful extensions: 6320
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 129
Number of HSP's that attempted gapping in prelim test: 4258
Number of HSP's gapped (non-prelim): 1007
length of query: 538
length of database: 18,247,518
effective HSP length: 107
effective length of query: 431
effective length of database: 14,195,856
effective search space: 6118413936
effective search space used: 6118413936
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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