Guide to the Human Genome
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Search of human proteins with 239753409

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239753409 PREDICTED: similar to hCG1811893 [Homo sapiens]
         (669 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239753409 PREDICTED: similar to hCG1811893 [Homo sapiens]         1363   0.0  
gi|153792764 hypothetical protein LOC57624 [Homo sapiens]            1241   0.0  
gi|62177127 myosin heavy chain Myr 8 [Homo sapiens]                   357   2e-98
gi|37537554 hypothetical protein FLJ37538 [Homo sapiens]              209   7e-54
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]         62   2e-09
gi|58530876 melanoma antigen family C, 1 [Homo sapiens]                62   2e-09
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    60   8e-09
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    56   9e-08
gi|163965366 nascent polypeptide-associated complex alpha subuni...    56   9e-08
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         56   9e-08
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    54   4e-07
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         54   6e-07
gi|55750053 atrophin-1 [Homo sapiens]                                  53   8e-07
gi|55750041 atrophin-1 [Homo sapiens]                                  53   8e-07
gi|47132519 Ras association and pleckstrin homology domains 1 is...    53   1e-06
gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]    53   1e-06
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    52   2e-06
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    52   2e-06
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  52   2e-06
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    51   3e-06
gi|146134388 YLP motif containing 1 [Homo sapiens]                     51   4e-06
gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]           50   5e-06
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    49   1e-05
gi|189011568 adenomatous polyposis coli [Homo sapiens]                 49   2e-05
gi|189011566 adenomatous polyposis coli [Homo sapiens]                 49   2e-05
gi|53759122 adenomatous polyposis coli [Homo sapiens]                  49   2e-05
gi|64084766 fidgetin [Homo sapiens]                                    48   3e-05
gi|38787970 tensin like C1 domain containing phosphatase isoform...    48   3e-05
gi|38787957 tensin like C1 domain containing phosphatase isoform...    48   3e-05
gi|38787941 tensin like C1 domain containing phosphatase isoform...    48   3e-05

>gi|239753409 PREDICTED: similar to hCG1811893 [Homo sapiens]
          Length = 669

 Score = 1363 bits (3529), Expect = 0.0
 Identities = 669/669 (100%), Positives = 669/669 (100%)

Query: 1   MISSKMMSSNPEEDPLDTFLQYIEDMGMKAYDGLVIQNASDIARENDRLRNETNLAYLKE 60
           MISSKMMSSNPEEDPLDTFLQYIEDMGMKAYDGLVIQNASDIARENDRLRNETNLAYLKE
Sbjct: 1   MISSKMMSSNPEEDPLDTFLQYIEDMGMKAYDGLVIQNASDIARENDRLRNETNLAYLKE 60

Query: 61  KNEKRRRQEEAIKRIGGEVGRGHEGSYVGKHFRMGFMTMPAPQDRLPHPCSSGFSVRSQS 120
           KNEKRRRQEEAIKRIGGEVGRGHEGSYVGKHFRMGFMTMPAPQDRLPHPCSSGFSVRSQS
Sbjct: 61  KNEKRRRQEEAIKRIGGEVGRGHEGSYVGKHFRMGFMTMPAPQDRLPHPCSSGFSVRSQS 120

Query: 121 LHSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPR 180
           LHSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPR
Sbjct: 121 LHSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPR 180

Query: 181 PHSDEYSKKIPPPKPKRNPNTQLSTSFDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPEE 240
           PHSDEYSKKIPPPKPKRNPNTQLSTSFDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPEE
Sbjct: 181 PHSDEYSKKIPPPKPKRNPNTQLSTSFDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPEE 240

Query: 241 EEPVYIEMVGNILRDFRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPT 300
           EEPVYIEMVGNILRDFRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPT
Sbjct: 241 EEPVYIEMVGNILRDFRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPT 300

Query: 301 VPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEV 360
           VPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEV
Sbjct: 301 VPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEV 360

Query: 361 TKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTL 420
           TKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTL
Sbjct: 361 TKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTL 420

Query: 421 YRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPV 480
           YRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPV
Sbjct: 421 YRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPV 480

Query: 481 SQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEK 540
           SQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEK
Sbjct: 481 SQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEK 540

Query: 541 STEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDGTPGPPVVTSRLGRCSVSP 600
           STEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDGTPGPPVVTSRLGRCSVSP
Sbjct: 541 STEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDGTPGPPVVTSRLGRCSVSP 600

Query: 601 TLLAGNHSSDLVLERNSGGGLDHESAWGSQDSQDVFQGALQDTQLPTKDIERTTMMSPGR 660
           TLLAGNHSSDLVLERNSGGGLDHESAWGSQDSQDVFQGALQDTQLPTKDIERTTMMSPGR
Sbjct: 601 TLLAGNHSSDLVLERNSGGGLDHESAWGSQDSQDVFQGALQDTQLPTKDIERTTMMSPGR 660

Query: 661 WLAKVMGSA 669
           WLAKVMGSA
Sbjct: 661 WLAKVMGSA 669


>gi|153792764 hypothetical protein LOC57624 [Homo sapiens]
          Length = 653

 Score = 1241 bits (3210), Expect = 0.0
 Identities = 617/652 (94%), Positives = 624/652 (95%), Gaps = 10/652 (1%)

Query: 1   MISSKMMSSNPEEDPLDTFLQYIEDMGMKAYDGLVIQNASDIARENDRLRNETNLAYLKE 60
           MISSKMMSSNPEEDPLDTFLQYIEDMGMKAYDGLVIQNASDIARENDRLRNETNLAYLKE
Sbjct: 1   MISSKMMSSNPEEDPLDTFLQYIEDMGMKAYDGLVIQNASDIARENDRLRNETNLAYLKE 60

Query: 61  KNEKRRRQEEAIKRIGGEVGRGHEGSYVGKHFRMGFMTMPAPQDRLPHPCSSGFSVRSQS 120
           KNEKRRRQEEAIKRIGGEVGRGHEGSYVGKHFRMGFMTMPAPQDRLPHPCSSGFSVRSQS
Sbjct: 61  KNEKRRRQEEAIKRIGGEVGRGHEGSYVGKHFRMGFMTMPAPQDRLPHPCSSGFSVRSQS 120

Query: 121 LHSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPR 180
           LHSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPR
Sbjct: 121 LHSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPR 180

Query: 181 PHSDEYSKKIPPPKPKRNPNTQLSTSFDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPEE 240
           PHSDEYSKKIPPPKPKRNPNTQLSTSFDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPEE
Sbjct: 181 PHSDEYSKKIPPPKPKRNPNTQLSTSFDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPEE 240

Query: 241 EEPVYIEMVGNILRDFRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPT 300
           EEPVYIEMVGNILRDFRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPT
Sbjct: 241 EEPVYIEMVGNILRDFRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPT 300

Query: 301 VPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEV 360
           VPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEV
Sbjct: 301 VPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEV 360

Query: 361 TKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTL 420
           TKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTL
Sbjct: 361 TKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTL 420

Query: 421 YRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPV 480
           YRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPV
Sbjct: 421 YRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPV 480

Query: 481 SQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEK 540
           SQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEK
Sbjct: 481 SQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEK 540

Query: 541 STEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDGTPGPPVVTSRLGRCSVSP 600
           STEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDGTPG PVVTSRLGRCSVSP
Sbjct: 541 STEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDGTPGTPVVTSRLGRCSVSP 600

Query: 601 TLLAGNHSSDLVLERNSG-----GGLDHESAWGSQDSQDVFQGALQDTQLPT 647
           TLLAGNHSS+  +    G      G+   S    + S D     LQ +Q+P+
Sbjct: 601 TLLAGNHSSEPKVSCKLGRSASTSGVPPPSVTPLRQSSD-----LQQSQVPS 647


>gi|62177127 myosin heavy chain Myr 8 [Homo sapiens]
          Length = 1858

 Score =  357 bits (916), Expect = 2e-98
 Identities = 252/595 (42%), Positives = 324/595 (54%), Gaps = 71/595 (11%)

Query: 12   EEDPLDTFLQYIEDMGMKAYDGLVIQNASDIARENDRLRNETNLAYLKEKNEKRRRQEEA 71
            E   +++FLQ  EDMG+K YD LVIQNASDIARENDRLR+E N  Y KEK E R  QEE 
Sbjct: 1177 EVTSINSFLQNTEDMGLKTYDALVIQNASDIARENDRLRSEMNAPYHKEKLEVRNMQEEG 1236

Query: 72   IKRIGGEVGRGHEGSYVGKHFRMGFMTMPAPQDRLPHPCSSGFSVRSQSLHSVGGTDDDS 131
             KR   + G         +HF    M++ A  D L   C  G S+ S SLHSV   DD S
Sbjct: 1237 SKRTDDKSGP--------RHFHPSSMSVCAAVDGLGQ-CLVGPSIWSPSLHSVFSMDDSS 1287

Query: 132  SCGS-RRQPPPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPRPHSDEYS--K 188
            S  S R+QPPPKPKRDP+T+LS S E VS   A  S       EA A+PRPHSD+YS  K
Sbjct: 1288 SLPSPRKQPPPKPKRDPNTRLSASYEAVS---ACLSAAREAANEALARPRPHSDDYSTMK 1344

Query: 189  KIPPPKPKRNPNTQLSTSFDETYIKKHGPRRTSLPRDSSLSQM-----------GSPAGD 237
            KIPP KPKR+PNT+LS S++E    + G  R +    ++   +            +P GD
Sbjct: 1345 KIPPRKPKRSPNTKLSGSYEEISGSRPGDARPAGAPGAAARVLTPGTPQCALPPAAPPGD 1404

Query: 238  PEEEEPVYIEMVGNILRDFRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCA 297
             ++ EPVYIEM+G+  R    +  D  E+VYEEMK  + DD G  A     H       A
Sbjct: 1405 EDDSEPVYIEMLGHAARP---DSPDPGESVYEEMKCCLPDDGGPGAGSFLLHG------A 1455

Query: 298  TPTVPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTP 357
            +P  P L  A       P G  CDIPPPFPNLL HRPPLLVFPP PV CSP SDESPLTP
Sbjct: 1456 SP--PLLHRAPEDEAAGPPGDACDIPPPFPNLLPHRPPLLVFPPTPVTCSPASDESPLTP 1513

Query: 358  LEVTKLPVLE-NVSYMKQPAGASPSTLPSHVPGHAKLEK---EQAAALG----------- 402
            LEV KLPVLE N+ Y  QP G+SP +     P ++K +K   ++ A+ G           
Sbjct: 1514 LEVKKLPVLETNLKYPVQPEGSSPLS-----PQYSKSQKGDGDRPASPGLALFNGSGRAS 1568

Query: 403  PASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKR--PPPYDAV 460
            P S  P     P PP   YR  +   +P      P+PV+ G++       +  P P  A 
Sbjct: 1569 PPSTPPPPPPPPGPPPAPYRPCAHLAFP----PEPAPVNAGKAGPSAEAPKVHPKPNSAP 1624

Query: 461  HSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSS 520
             +G  S S P +P+S  +    D  K  ++A      +P  SR    +SPL+EL SLF+S
Sbjct: 1625 VAGPCS-SFPKIPYSPVKATRADARKAGSSASPPAPYSPPSSRPL--SSPLDELASLFNS 1681

Query: 521  GRSLLRKSSSGRRSKEPAEKSTEELKVRSH----STEPLPKLDNKERGHHGASSS 571
            GRS+LRKS++GR+ +E AE     + + S     ++E   +  ++   +HG   S
Sbjct: 1682 GRSVLRKSAAGRKIRE-AEGFETNMNISSRDDPSTSEITSETQDRNANNHGIQLS 1735


>gi|37537554 hypothetical protein FLJ37538 [Homo sapiens]
          Length = 841

 Score =  209 bits (532), Expect = 7e-54
 Identities = 160/451 (35%), Positives = 206/451 (45%), Gaps = 95/451 (21%)

Query: 54  NLAYLKEKNEKRRRQEEAIKR-----------IGGEVGRG-----HEGSYVGKHFRMGFM 97
           NL Y K K E R+ +EE  KR            G   G+G      + + + +  RMGFM
Sbjct: 2   NLLYRKTKLEWRQHKEEEAKRSSSKEVAPAGSAGPAAGQGPGVRVRDIASLRRSLRMGFM 61

Query: 98  TMPAPQDRLPHPCSSGFSVRSQSLHSVGGTDD------DSSCG-----SRRQPPPKPKRD 146
           TMPA Q+  PHPC S  + RS S HSVG  D        +S G     S R+PP KP+R 
Sbjct: 62  TMPASQEHTPHPCRSAMAPRSLSCHSVGSMDSVGGGPGGASGGLTEDSSTRRPPAKPRRH 121

Query: 147 PSTKLSTSSETVSSTAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRNPNTQLSTS 206
           PSTKLS           S +   P +   S KP P   E S+K+PP KP+R+PNTQLS S
Sbjct: 122 PSTKLSMVGP------GSGAETPPSKKAGSQKPTPEGRESSRKVPPQKPRRSPNTQLSVS 175

Query: 207 FDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPE---EEEPVYIEMVGNILRDFRK----- 258
           FDE+      PR  +LP    L++    AGDP+   +EEPVYIEMVG++ R   +     
Sbjct: 176 FDESCPPGPSPRGGNLPL-QRLTRGSRVAGDPDVGAQEEPVYIEMVGDVFRGGGRSGGGL 234

Query: 259 -----------------EDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTV 301
                             D ++SEA+YEEMKYP+ ++ G+         + +S    P  
Sbjct: 235 AGPPLGGGGPTPPAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSPPQQPHA 294

Query: 302 --PDLDFAKASV------PCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDES 353
             P      AS         P K   C+IPPPFPNLL HRPPLL FP A        D  
Sbjct: 295 LPPHAHRRPASALPSRRDGTPTKTTPCEIPPPFPNLLQHRPPLLAFPQAKSASRTPGD-- 352

Query: 354 PLTPLEVTKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSS 413
                 V++LPVL    + K+PAG++P                  A   PA         
Sbjct: 353 -----GVSRLPVL---CHSKEPAGSTP------------------APQVPARERETPPPP 386

Query: 414 PPPPSTLYRTQSPHGYPKSHSTSPSPVSMGR 444
           PPPP+       P G  +SHST   P   G+
Sbjct: 387 PPPPAANLLLLGPSGRARSHSTPLPPQGSGQ 417



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 89/350 (25%), Positives = 128/350 (36%), Gaps = 80/350 (22%)

Query: 290 HSCSSQCATPTVPDLDFAKASVPCPPKGLLCDIPPPFPNLL---------SHRPPL---- 336
           HS     +TP  P +   +   P PP       PPP  NLL         SH  PL    
Sbjct: 362 HSKEPAGSTPA-PQVPARERETPPPPP------PPPAANLLLLGPSGRARSHSTPLPPQG 414

Query: 337 -------LVFPPAPVHCSPNSDESPLTPLEVTKL----PVLENVSYMKQPAGASPST--- 382
                     P +     P +  +P  P     L    P  + VSY    +    +T   
Sbjct: 415 SGQPRGERELPNSHSMICPKAAGAPAAPPAPAALLPGPPKDKAVSYTMVYSAVKVTTHSV 474

Query: 383 LPSHVP---GHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHG----------Y 429
           LP+  P   G  K EKE +   G        SS PP P       SPHG          +
Sbjct: 475 LPAGPPLGAGEPKTEKEISVLHGMLCT----SSRPPVPGKT----SPHGGAMGAAAGVLH 526

Query: 430 PKSHSTSPS--PVSMGRSLTPL--------SLKRPPPYDAVHSGSLSRSSPSVPHSTPRP 479
            +    SP   P      LTPL         LKRPP Y+++ +G +      V   +P  
Sbjct: 527 HRGCLASPHSLPDPTVGPLTPLWTYPATAAGLKRPPAYESLKAGGVLNKGCGVGAPSPMV 586

Query: 480 VSQ------DGAKMVNAAVNTYGAAPGGSRSRTPTSPLEEL-TSLFSSGRSLLRKSSSGR 532
             Q      DG    + +     A+ G     TP    EE+  + F +G +L RK   G 
Sbjct: 587 KIQLQEQGTDGGAFASISCAHVIASAG-----TPEEEEEEVGAATFGAGWALQRKVLYGG 641

Query: 533 RSKEPAEKSTEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDG 582
           R  +  +K  +  +  + S E   K++ ++R   G  +S  PV++Q  +G
Sbjct: 642 RKAKELDKVEDGARAWNGSAEGPGKVEREDR---GPGTSGIPVRSQGAEG 688



 Score = 30.0 bits (66), Expect = 7.2
 Identities = 53/229 (23%), Positives = 79/229 (34%), Gaps = 36/229 (15%)

Query: 375 PAGASPSTLPSH-VPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYPK-S 432
           PAGA   +  S  +    K    + A  G A+  P L+++ PP       Q PH  P  +
Sbjct: 247 PAGADSDSEESEAIYEEMKYPLPEEAGEGRANGPPPLTATSPP-------QQPHALPPHA 299

Query: 433 HSTSPSPVSMGRSLTPLSL---KRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQD-GAKMV 488
           H    S +   R  TP      + PPP+  +    L    P +     +  S+  G  + 
Sbjct: 300 HRRPASALPSRRDGTPTKTTPCEIPPPFPNL----LQHRPPLLAFPQAKSASRTPGDGVS 355

Query: 489 NAAVNTYGAAPGGSRSRTPTSPLEELTSLFSS----GRSLLRKSSSGRRSKEPAEKSTEE 544
              V  +   P GS +  P  P  E  +          +LL    SGR            
Sbjct: 356 RLPVLCHSKEPAGS-TPAPQVPARERETPPPPPPPPAANLLLLGPSGR------------ 402

Query: 545 LKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDGTPGPPVVTSRL 593
              RSHST   P+   + RG     +S   +  +       PP   + L
Sbjct: 403 --ARSHSTPLPPQGSGQPRGERELPNSHSMICPKAAGAPAAPPAPAALL 449


>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
          Length = 1682

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 129/563 (22%), Positives = 183/563 (32%), Gaps = 94/563 (16%)

Query: 100  PAPQDRLPH------PCSSGFSVRSQSLH--------------SVGGTDDDSSCGSRRQP 139
            PAP   LPH      P +S FSV +Q  H              S  G+   S  G    P
Sbjct: 514  PAPPP-LPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFP 572

Query: 140  PP------------------KPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPR- 180
            PP                   P+  P   L+ +      ++  ++     R   S +PR 
Sbjct: 573  PPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRV 632

Query: 181  --PHSDEYSKKIPPPKPKRNPNTQLSTSFDETYIKKHGPRRTSLPRDSSLSQMGSPAGDP 238
              P + E     PPP P       +     E  +   GPR    P      Q   PA   
Sbjct: 633  SFPKTPEVGPG-PPPGPLSKAPQPVPPGVGE--LPARGPRLFDFPPTPLEDQFEEPA--- 686

Query: 239  EEEEPVYIEMVGNILR----DFRKEDDDQSEAVYEEMKYPI---FDDLGQDAKCDFDHHS 291
              E  +  + + NI++      RKE++ Q        + P+   F  L      D    +
Sbjct: 687  --EFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTT 744

Query: 292  CSSQCATPTVPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSD 351
             +   A  T         +     K     +PPP P L    PP    PP P   SP S 
Sbjct: 745  TAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPP-PPLAKFPPPSQPQPPPPPPPSPAS- 802

Query: 352  ESPLTPLEVTKLPVLENVSYMKQPAGASPSTLPSHVPG--HAKLEKEQAAALGPASATPA 409
                  L  +   VLE   Y  +  GA+ ST P  +P   ++      A AL P SA P+
Sbjct: 803  ------LLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPS 856

Query: 410  LSSSPPPPSTLYRTQSPHGYP----KSHSTSPSPVSMGRSLTPLSLKRPPPYD------- 458
               SP P ++     S  G P    +     P P  M  +  P  L  PP          
Sbjct: 857  AQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEE 916

Query: 459  -------AVHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAA-----VNTYGAAPGGSRSRT 506
                    V     S + P+ P  T  P      +++  A          A  G  + R 
Sbjct: 917  ISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKRRQ 976

Query: 507  PTSPLEELTSLFSSGRSLLRKSSSGR---RSKEPAEKSTEELKVRSHSTEPLPKLDNKER 563
                 E      +   S+ R+   GR   ++K P EKS   L      +E +   + K R
Sbjct: 977  KEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGRE-KSR 1035

Query: 564  GHHGASSSREPVKAQEWDGTPGP 586
               G +S  +P  A      P P
Sbjct: 1036 PDLGGASKAKPPTAPAPPSAPAP 1058



 Score = 34.3 bits (77), Expect = 0.38
 Identities = 65/293 (22%), Positives = 94/293 (32%), Gaps = 49/293 (16%)

Query: 323 PPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLENVSYMKQPAGASPST 382
           P P P   +H P   + P AP    P                        + P   S   
Sbjct: 314 PYPAPAYTAHPPGHRLVPAAPPGPGP------------------------RPPGAESHGC 349

Query: 383 LPSHVPGHAKLEKEQA------AALGPASATPALSSSPPPPSTLYRTQSPHGYPKSHSTS 436
           LP+  P  + L + +       +++ PA+ T  +  +P  P  L  T +      S +T 
Sbjct: 350 LPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTG 409

Query: 437 PSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTYG 496
              V     +      + P  +  H G L  S+    HS+ +P    GA    AA     
Sbjct: 410 LRGVEPNPGIPGADHYQTPALEVSHHGRLGPSA----HSSRKPFL--GAP---AATPHLS 460

Query: 497 AAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEKSTEELKVRSHSTEPLP 556
             PG S    P  P      L         K  + R ++E  E   E          P P
Sbjct: 461 LPPGPSSPPPPPCP----RLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAP 516

Query: 557 KLDNKERGHHGASSSREPVKAQEWDGTPGPPVVTSRLGRCSVSPTLLAGNHSS 609
                  G  G  +SR  V  Q+    P PP  T+       S    +G+HSS
Sbjct: 517 PPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTS------SSNSNSGSHSS 563



 Score = 34.3 bits (77), Expect = 0.38
 Identities = 58/230 (25%), Positives = 75/230 (32%), Gaps = 42/230 (18%)

Query: 315 PKGLLCDIPPPFPNLLSHRPPLLVFPPA----PVHCSPNSDESPLT--------PLEVTK 362
           P G     PPP P LL  RPP    PPA    P   +   D   L         P     
Sbjct: 462 PPGPSSPPPPPCPRLL--RPPP---PPAWLKGPACRAAREDGEILEELFFGTEGPPRPAP 516

Query: 363 LPVLENVSYMKQPAGA-SPSTLPSHVP----------GHAKLEKEQAAALGPASATP--- 408
            P+     ++  PA   S  T  SH P           ++      ++  GP S  P   
Sbjct: 517 PPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPY 576

Query: 409 ---ALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSL 465
              ++   P PPS     Q P   P + +  P+P S     T  S +RP       S   
Sbjct: 577 LARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRP------ESPRP 630

Query: 466 SRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAP--GGSRSRTPTSPLEE 513
             S P  P   P P     +K         G  P  G      P +PLE+
Sbjct: 631 RVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLED 680


>gi|58530876 melanoma antigen family C, 1 [Homo sapiens]
          Length = 1142

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 112/469 (23%), Positives = 179/469 (38%), Gaps = 56/469 (11%)

Query: 102 PQDRLPHPCSSGFSVRSQSLHSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTSSETVSST 161
           PQ  L  P SS FS    SL         S+     Q P         ++  SS + SST
Sbjct: 439 PQSPLQIPVSSSFSYTLLSLFQSSPERTHSTFEGFPQSP--------LQIPVSSSSSSST 490

Query: 162 AASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRNPNTQLSTSFD--ETYIKKHGPRR 219
             S    +PE T+++ +  P S     + PP     +   Q+  S    E  +  H   +
Sbjct: 491 LLSLFQSSPECTQSTFEGFPQSPLQIPQSPPEGENTHSPLQIVPSLPEWEDSLSPHYFPQ 550

Query: 220 TSLPRDSSLSQMGSPAGDPEEEE-------PVYIEMVGNILRDFRKEDDDQSEAVYEEMK 272
           +    + SLS    P   P+ E+       P   +   ++   +  +   Q E     + 
Sbjct: 551 SPPQGEDSLSPHYFPQSPPQGEDSLSPHYFPQSPQGEDSLSPHYFPQSPPQGEDSMSPLY 610

Query: 273 YPIFDDLGQDAKCDFDHHSCSSQCATPTVPDLDFAKASVPCPPKGLLCDIPPPFPNLLSH 332
           +P     G++ +            +TP+     F ++S   PP+G     P   P     
Sbjct: 611 FPQSPLQGEEFQSSLQSPVSICSSSTPSSLPQSFPESS-QSPPEG-----PVQSPLHSPQ 664

Query: 333 RPPLLVFPPAPVHCSPNS---DESPLTPLEVTKLPV-----LENVSYMKQPAGASPSTLP 384
            PP  +   +P+  SP S    E  L+PL++ + P+     L ++ + + P     S  P
Sbjct: 665 SPPEGMHSQSPLQ-SPESAPEGEDSLSPLQIPQSPLEGEDSLSSLHFPQSPPEWEDSLSP 723

Query: 385 SHVPGH-AKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSP--SPVS 441
            H P    + E  Q++   P S   + +S   P S     +SP   P+  + SP   PVS
Sbjct: 724 LHFPQFPPQGEDFQSSLQSPVSICSSSTSLSLPQSF---PESPQSPPEGPAQSPLQRPVS 780

Query: 442 MGRSLTPLSL-------KRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNT 494
              S T  SL        + PP     S  L     S P ST   +SQ      ++ V++
Sbjct: 781 SFFSYTLASLLQSSHESPQSPPEGPAQS-PLQSPVSSFPSSTSSSLSQ------SSPVSS 833

Query: 495 YGAAPGGSRSR-TPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEKST 542
           + ++   S S+ +P SPL+     FSS  SL   S     S  P ++ T
Sbjct: 834 FPSSTSSSLSKSSPESPLQSPVISFSSSTSL---SPFSEESSSPVDEYT 879



 Score = 32.0 bits (71), Expect = 1.9
 Identities = 51/199 (25%), Positives = 73/199 (36%), Gaps = 48/199 (24%)

Query: 375 PAGASPSTLPSHVPGHAKLEKEQAAALGPASATPAL--SSSPPPPSTLYRTQSPHGYPKS 432
           P    PS L S        E  Q+   G  S +P     SSP    TLY  QSP    + 
Sbjct: 7   PTAGMPSLLQS------SSESPQSCPEGEDSQSPLQIPQSSPESDDTLYPLQSPQSRSEG 60

Query: 433 HSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAV 492
             +S              L+RPP       G  S+S   +P S+P     +G    +   
Sbjct: 61  EDSSD------------PLQRPP------EGKDSQSPLQIPQSSP-----EGDDTQSPLQ 97

Query: 493 NTYGAAPGGSRSRTP-------------TSPLEELTSLFSSGRSLLRKSSSGRRSKEPAE 539
           N+  ++P G  S +P              SPL+   S F S   L    SS   ++ P E
Sbjct: 98  NSQ-SSPEGKDSLSPLEISQSPPEGEDVQSPLQNPASSFFSSALLSIFQSSPESTQSPFE 156

Query: 540 ---KSTEELKVRSHSTEPL 555
              +S  ++ V + S+  L
Sbjct: 157 GFPQSVLQIPVSAASSSTL 175


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 59.7 bits (143), Expect = 8e-09
 Identities = 141/554 (25%), Positives = 198/554 (35%), Gaps = 121/554 (21%)

Query: 100 PAPQDRLPHPCSSG--FSVRSQSLHSVGGTDDDSSCGSRRQPPPKP--KRDPSTKLSTSS 155
           PAP  R P P + G   SV S S HS      + S  +RR+P      +R  S  LS+S+
Sbjct: 192 PAPSAR-PRPPTEGPRKSVSSASEHST----TEPSPAARRRPSAGGGLQRPASRSLSSSA 246

Query: 156 ETVSSTAAS--KSGKTPERTEASAKPRPHSDEYSK--KIPPPKPKRNP------NTQLST 205
             +SS A S   +  TP      ++P+P   +  +  ++ PP+    P      ++ L+T
Sbjct: 247 TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 306

Query: 206 SFDETYIKKHGPRRT-SLPRDSSLS-QMGSPA--GDPEEEEPVYIEMVGNILRDFRKEDD 261
                 ++   P    + P  SSL+ Q+ +P     P    P  ++ + +          
Sbjct: 307 PSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPS------PPAT 360

Query: 262 DQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTVPDLDFAKASVPCPPKGLLCD 321
             S+A            LG                     P L    + +P PP   L  
Sbjct: 361 PPSQAT---------TSLGS--------------------PTLQATHSFLPSPPLSPLAT 391

Query: 322 IPPPFPNLLSHRPPLLV--FPPAPVHCSPNSDESPLTP--LEVTKL----------PVLE 367
            PP  P  L+  PPL     PPA    SP +  SP  P  L V  L          PV  
Sbjct: 392 PPPQAPPALA-LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 450

Query: 368 NVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPS-------TL 420
             S    P  +  +T PS  P        Q     PAS   + S++PPP +        L
Sbjct: 451 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 510

Query: 421 YRTQSPHGYPKSHSTSP--------------SPVSMGRSLTPLSLKRPPPY-DAVHSGSL 465
              + P   P + +T P              +P S   SL    L  PPP    V +  L
Sbjct: 511 QLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL 570

Query: 466 SRSSPSVPHSTP-----RPVSQDGAKMVNAAVNTYGAAPG--GSRSRTPTSPLEELTSLF 518
            +  PS P S       RP +      V+    T   APG     SR+P+S L       
Sbjct: 571 LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL------- 623

Query: 519 SSGRSLLRKSSSGRRSKEPAEKSTEELKVRSHSTE----PLPKLDNKERGHHGASSSREP 574
            SG  L   SSS       A  + EEL+      E      P  D +    H A+ SR P
Sbjct: 624 -SGPDLAGHSSS-------ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP 675

Query: 575 VKAQEWDGTPGPPV 588
                + G PG P+
Sbjct: 676 APPLAFRGAPGAPL 689



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 77/334 (23%), Positives = 111/334 (33%), Gaps = 68/334 (20%)

Query: 327 PNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLENVS---YMKQPAGASPSTL 383
           P LL+ RPP    PP PV           TP  +  L     V      ++  G   +T+
Sbjct: 22  PGLLTPRPPGSPRPPPPV-----------TPAALRVLGAAGAVGRKPLAERAGGIGGATI 70

Query: 384 PSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYP--KSHSTSPSP-- 439
           P   P          ++  PAS  PA       P     +  P   P   S +T P P  
Sbjct: 71  PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG 130

Query: 440 -----VSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNT 494
                +S   ++        P   A+ +G+   +S   P  TP P     ++     V  
Sbjct: 131 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP-GTPSPAMARRSRAAGTEVGL 189

Query: 495 YGAAPGGSRSRTPTSPLEELTSLFSS------GRSLLRKSSSGRRSKEPAEKSTEEL--- 545
              AP  +R R PT    +  S  S         +  R+ S+G   + PA +S       
Sbjct: 190 PRPAP-SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP 248

Query: 546 ---------------KVRSHSTEPLPKLDNKERGHHGASSSREP-VKAQEWDGTPG-PPV 588
                          +  +H ++P PK         G  + R P V     D  P   P+
Sbjct: 249 LSSPARSGPSARGTPRAPAHPSQPKPK---------GLQALRPPQVTPPRKDAAPALGPL 299

Query: 589 VTSRLGRCSVS--------PTLLAGNHSSDLVLE 614
            +S L   S S        PTL A  HSS L  +
Sbjct: 300 SSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQ 333


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 56.2 bits (134), Expect = 9e-08
 Identities = 136/545 (24%), Positives = 187/545 (34%), Gaps = 133/545 (24%)

Query: 100 PAPQDRLPHPCSSG--FSVRSQSLHSVGGTDDDSSCGSRRQPPPKPKRDPSTK---LSTS 154
           PAP  R P P + G   SV S S HS              +P P  +R PS        +
Sbjct: 183 PAPSAR-PRPPTEGPRKSVSSASEHST------------TEPSPAARRRPSAGGGLQRPA 229

Query: 155 SETVSSTAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRNPNTQLSTSFDETYIKK 214
           S ++SS+A   S  +P R+  SA+  P +  +  +   PKPK               ++ 
Sbjct: 230 SRSLSSSATPLS--SPARSGPSARGTPRAPAHPSQ---PKPKG--------------LQA 270

Query: 215 HGPRRTSLPRDSSLSQMG----SPAGDPEEEEPVYIEMVGNILRDFRKEDDDQSEAVYEE 270
             P + + PR  +   +G    SP   P    P                    +    + 
Sbjct: 271 LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAP----------------PSPSAPPSLQT 314

Query: 271 MKYPIFDDLGQDAKCDFDHHSCSSQCATPTVPDLDFAKASVPCPPKGLLCDIPPPFPNLL 330
           +  P      Q           ++   +PT   L    + +P PP   L   PP  P  L
Sbjct: 315 LPSPPATPPSQ----------ATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPAL 361

Query: 331 SHRPPLLV--FPPAPVHCSPNSDESPLTP--LEVTKL----------PVLENVSYMKQPA 376
           +  PPL     PPA    SP +  SP  P  L V  L          PV    S    P 
Sbjct: 362 A-LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 420

Query: 377 GASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPS-------TLYRTQSPHGY 429
            +  +T PS  P        Q     PAS   + S++PPP +        L   + P   
Sbjct: 421 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA 480

Query: 430 PKSHSTSP--------------SPVSMGRSLTPLSLKRPPPY-DAVHSGSLSRSSPSVPH 474
           P + +T P              +P S   SL    L  PPP    V +  L +  PS P 
Sbjct: 481 PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA 540

Query: 475 STP-----RPVSQDGAKMVNAAVNTYGAAPG--GSRSRTPTSPLEELTSLFSSGRSLLRK 527
           S       RP +      V+    T   APG     SR+P+S L        SG  L   
Sbjct: 541 SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL--------SGPDLAGH 592

Query: 528 SSSGRRSKEPAEKSTEELKVRSHSTE----PLPKLDNKERGHHGASSSREPVKAQEWDGT 583
           SSS       A  + EEL+      E      P  D +    H A+ SR P     + G 
Sbjct: 593 SSS-------ATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGA 645

Query: 584 PGPPV 588
           PG P+
Sbjct: 646 PGAPL 650



 Score = 38.9 bits (89), Expect = 0.016
 Identities = 64/261 (24%), Positives = 96/261 (36%), Gaps = 38/261 (14%)

Query: 327 PNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLENVS---YMKQPAGASPSTL 383
           P LL+ RPP    PP PV           TP  +  L     V      ++  G   +T+
Sbjct: 22  PGLLTPRPPGSPRPPPPV-----------TPAALRVLGAAGAVGRKPLAERAGGIGGATI 70

Query: 384 PSHVP--GHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSP-- 439
           P   P  G  +  +  A+  G   A PA ++SP P S+  R         S +T P P  
Sbjct: 71  PESAPRAGPTRTSRPPASGRG-ERAPPAKNTSPGPVSSPGRA--------SGTTRPGPLG 121

Query: 440 -----VSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNT 494
                +S   ++        P   A+ +G+   +S   P  TP P     ++     V  
Sbjct: 122 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP-GTPSPAMARRSRAAGTEVGL 180

Query: 495 YGAAPGGSRSRTPT-SPLEELTSLFSSGRSLLRKSSSGRRSKEPAEKSTEELKVRSHSTE 553
              AP  +R R PT  P + ++S  +S  S    S + RR +  A    +    RS S+ 
Sbjct: 181 PRPAP-SARPRPPTEGPRKSVSS--ASEHSTTEPSPAARR-RPSAGGGLQRPASRSLSSS 236

Query: 554 PLPKLDNKERGHHGASSSREP 574
             P       G     + R P
Sbjct: 237 ATPLSSPARSGPSARGTPRAP 257


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 56.2 bits (134), Expect = 9e-08
 Identities = 101/460 (21%), Positives = 158/460 (34%), Gaps = 64/460 (13%)

Query: 140  PPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRNP 199
            PP PK  P+T     + T  +        +P        P P +      + PP PK  P
Sbjct: 1294 PPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPA------VTPPSPKGTP 1347

Query: 200  NTQLSTSFDE----TYIKKHGPRRTSLPRDSSLSQMGSPAGDPEEEEPVYIEMVGNILRD 255
                +T   +    T   K GP     P  ++ S  G PA  P   +       G  +  
Sbjct: 1348 TLPATTPSSKGGPTTPSSKEGPT----PPAATPSHKGGPAMTPPSPKR------GPAIPS 1397

Query: 256  FRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTVPDLDFAKASVPCPP 315
             + +    +       K P      + A               P V  +   KA     P
Sbjct: 1398 PKGDPTSPAVIPLSPKKAPATPVTREGAATP-----SKGDLTPPAVTPVSLKKAPATSAP 1452

Query: 316  KG-LLCDIPPPFPNLLSHRPPLLVFPPAP--VHCSPNSDESPLTP--LEVTKLPVLENVS 370
            KG          P L +  PP    PPAP  V  S +  ++P TP  +    LP +   S
Sbjct: 1453 KGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSS 1512

Query: 371  YMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASA-------------TPALSS---SP 414
              + PA  S    P   P    L K+  A L P  A             TPA+ +   +P
Sbjct: 1513 PKEVPATPSSRRDPI-APTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAP 1571

Query: 415  PPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPH 474
              PS+   +  P   P ++  +PSP  +   L P ++  P P +A    +++  SP    
Sbjct: 1572 ATPSSKEASSPPAVTPSTYKGAPSPKEL---LIPPAVTSPSPKEAPTPPAVTPPSPEKGP 1628

Query: 475  STPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRS 534
            +TP P     +  V  +          S   +PTSP     S+     + + ++S G  +
Sbjct: 1629 ATPAPKGTPTSPPVTPS----------SLKDSPTSP----ASVTCKMGATVPQASKGLPA 1674

Query: 535  KEPAEKSTEELKVRSHSTEPLPKLDNKERGHHGASSSREP 574
            K+      E L   +  + P+     ++      SS+  P
Sbjct: 1675 KKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSP 1714



 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 87/386 (22%), Positives = 125/386 (32%), Gaps = 36/386 (9%)

Query: 141  PKPKRDPSTKLSTSSETVSSTAAS--KSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRN 198
            P PK  P+T     +  +S T++S  K+  TP      A P P          PP PK  
Sbjct: 894  PFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGG 953

Query: 199  PNTQLSTSFDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPEEEEPVYIEMVGNILRDFRK 258
            P T  S  +  T      P   + P         SP G P           G       K
Sbjct: 954  PATP-SPKWAPT------PPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPK 1006

Query: 259  EDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTVPDLDFAKASVPCP---P 315
                         K       G  A   F   + +   ATP  P    + A+ P P   P
Sbjct: 1007 GAPTPPAVTPPSPK-------GSPAATPFPKGASTPPAATPPSPK--GSPAATPLPKGAP 1057

Query: 316  KGLLCDIPPP-----FPNLLSHRPPLLVFPPAPVH--CSPNSDESPLTPLEVTKLPVLEN 368
                  +P P      P+L     P    PP+P     +P+   +P+ P      P    
Sbjct: 1058 TTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGL 1117

Query: 369  VSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALS---SSPPPPSTLYRTQS 425
             +   + A  +P+  P    G       + A   PA+  P+     ++PPP        +
Sbjct: 1118 ATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA 1177

Query: 426  PHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHST-PRPVSQDG 484
                PK    +PSP   G   TP +   P P   + + S  + +P+ P +T P P     
Sbjct: 1178 TPPSPKGGLATPSP--KGAPTTPAATP-PSPKGGLATPS-PKGAPTTPAATPPSPKGGLA 1233

Query: 485  AKMVNAAVNTYGAAPGGSRSRTPTSP 510
                  A  T  A P   +    T P
Sbjct: 1234 TPSPKGAPTTPAATPPSPKGGPATPP 1259



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 47/168 (27%), Positives = 65/168 (38%), Gaps = 20/168 (11%)

Query: 340  PPAPVHCSPNSDESPLTPLEVTKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAA 399
            PP+P      S  +PL+P  VT  P        K+    S   LP    G A    +QA 
Sbjct: 858  PPSPKGAPTPSAVTPLSPKGVTLPP--------KETPTPSVVNLPFPKEGPATPAPKQAP 909

Query: 400  ALGPASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDA 459
            AL   S++P  + + P P  +  + SP G P   + +P P   G   TP     P P   
Sbjct: 910  ALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATP-PSPKGGPATPSPKWAPTP--- 965

Query: 460  VHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTP 507
                    ++P  P   P   S  GA    AA  T  +  GG  + +P
Sbjct: 966  ------PAATPPSPKGGPATPSPKGAPTPPAA--TPPSPKGGPATPSP 1005



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 71/305 (23%), Positives = 107/305 (35%), Gaps = 30/305 (9%)

Query: 298  TPTVPDLDFA---KASVPCPPKGLLCDIPP---PFPNLLSHRPPLLVFP------PAPVH 345
            +PT P    A    A  P  PKG+   +PP   P P++++     L FP      PAP  
Sbjct: 855  SPTPPSPKGAPTPSAVTPLSPKGVT--LPPKETPTPSVVN-----LPFPKEGPATPAPKQ 907

Query: 346  CSPNSDESPLTPLEVTKLPVLENVSYMKQPAGAS--PSTLPSHVPGHAKLEKEQAAALGP 403
             +P    +  +P +    P  + +     P GA   P+  P    G       + A   P
Sbjct: 908  -APALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPP 966

Query: 404  ASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSG 463
            A+  P+    P  PS       P   P S    P+  S   + TP ++  P P  +  + 
Sbjct: 967  AATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAAT 1026

Query: 464  SLSRSSPSVPHST-PRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGR 522
               + + + P +T P P     A  +     T  AA   S    P +P     SL   G 
Sbjct: 1027 PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATP-----SL--KGA 1079

Query: 523  SLLRKSSSGRRSKEPAEKSTEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWDG 582
                 ++       PA  S +   +   +T P PK       H GA ++          G
Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGG 1139

Query: 583  TPGPP 587
               PP
Sbjct: 1140 LATPP 1144



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 84/355 (23%), Positives = 107/355 (30%), Gaps = 50/355 (14%)

Query: 140  PPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRNP 199
            PP PK  P+T     + T  +         P      A P P        + PP PK +P
Sbjct: 970  PPSPKGGPATPSPKGAPTPPAATP------PSPKGGPATPSPKGAPTPPAVTPPSPKGSP 1023

Query: 200  NTQLSTSFDETYIKKHGPRRTSLPRDSSL-SQMGSPAGDPEEEEPVYIEMVGNILRDFRK 258
                +T F         P+  S P  ++  S  GSPA  P  +        G        
Sbjct: 1024 ---AATPF---------PKGASTPPAATPPSPKGSPAATPLPK--------GAPTTPAAT 1063

Query: 259  EDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTVPDLDFAKASVPCPPKGL 318
                +       +K       G          S     ATP+        A+ P  PKG 
Sbjct: 1064 LPSPKGGPATPSLK-------GAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGG 1116

Query: 319  LCDIP-----------PPFPNLLSHRPPLLVFP--PAPVHCSPNSDESPLTPLEVTKLPV 365
            L   P           PP P      PP    P  PA    SP    +   P      P 
Sbjct: 1117 LATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPA 1176

Query: 366  LENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQS 425
                S     A  SP   P+         K   A   P  A    +++PP P     T S
Sbjct: 1177 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS 1236

Query: 426  PHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPH-STPRP 479
            P G P + + +P P   G   TP     P P  A    SL     + PH   P P
Sbjct: 1237 PKGAPTTPAATP-PSPKGGPATPPPKGAPTP-PAATPPSLKGGLATPPHKGAPNP 1289



 Score = 36.2 bits (82), Expect = 0.10
 Identities = 58/252 (23%), Positives = 79/252 (31%), Gaps = 41/252 (16%)

Query: 297  ATPTVPDLDFAKASVPCPPKGLLCDIPP-------------PFPNLLSHRPPLLVFPPAP 343
            ATP         A+ P  PKG L   PP             P   L +  P      PA 
Sbjct: 1141 ATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1200

Query: 344  VH-------CSPNSDESPLTPLEVTKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKE 396
                      +P+   +P TP      P     +   + A  +P+  P    G       
Sbjct: 1201 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPP 1260

Query: 397  QAAALGPASATPALSS----------------SPPPPSTLYRTQSPHGYPKSHSTSPSPV 440
            + A   PA+  P+L                  +PP P     T  P G P   + +P P 
Sbjct: 1261 KGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATP-PS 1319

Query: 441  SMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPG 500
              G   TP     P P  AV   S  + +P++P +TP                   A P 
Sbjct: 1320 PKGSPGTPPPKGAPTP-PAVTPPS-PKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPS 1377

Query: 501  --GSRSRTPTSP 510
              G  + TP SP
Sbjct: 1378 HKGGPAMTPPSP 1389



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 41/157 (26%), Positives = 57/157 (36%), Gaps = 32/157 (20%)

Query: 340 PPAPVHCSPNSDESPL-----------------TPLEVTKLPVLENVSYMKQPAGASPST 382
           P  P  CSP   + PL                 TPLEV   P  ++ S    P G +P  
Sbjct: 43  PTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEV---PFPQSSSGTALPLGTAPEA 99

Query: 383 LPSHVPGHAKLEKEQAAALGPASATPALS-SSPPPPSTLYRTQSPHGYPKSHSTSPSPVS 441
            P+ +P            +GP  +  AL+ +SP    TL  T S        + +P  V 
Sbjct: 100 -PTFLPN----------LIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQ 148

Query: 442 MGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPR 478
              +  P  L  PP      SGS+   S  +  S P+
Sbjct: 149 KSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPK 185



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 59/249 (23%), Positives = 89/249 (35%), Gaps = 36/249 (14%)

Query: 290 HSCSSQCATPTVPDLDFAKASVPCPPKGLLCDIPPPFPNL--LSHRPPLLVFPPAPVHCS 347
           ++C+        P++  +  S   PP G     PP    +  +SH   L     +P  C 
Sbjct: 716 NTCAPLATLVLAPEIPKSVPSPSLPPAGT----PPGTKKVDGISHTSALAPVASSPKECP 771

Query: 348 PN--------SDESPLTPLEVTKLPVLENVS-YMKQP----AGASPST----LPSHV-PG 389
                     S +  LT L  +  P+  +VS   K+P      A P T    L S V P 
Sbjct: 772 TEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPV 831

Query: 390 HAKLEKEQAAALGPASATPALSSSPPPPS-------TLYRTQSPHGYPKSHSTSPSPVSM 442
            A    E + +   +  +PA + SP PPS       +     SP G       +P+P  +
Sbjct: 832 EASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVV 891

Query: 443 GRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAP--- 499
                      P P  A  + S++ SSP    +TP P     +     A     A P   
Sbjct: 892 NLPFPKEGPATPAPKQA-PALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSP 950

Query: 500 -GGSRSRTP 507
            GG  + +P
Sbjct: 951 KGGPATPSP 959



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 118/533 (22%), Positives = 164/533 (30%), Gaps = 111/533 (20%)

Query: 134  GSRRQPPPKPKRDP---STKLSTSSETVSSTAASKSGKTPERTEASAKPR------PHSD 184
            G     PP PKR P   S K   +S  V   +  K+  TP   E +A P       P   
Sbjct: 1380 GGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVT 1439

Query: 185  EYSKKIPPPK--PKRNPNTQLSTSFDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPEEEE 242
              S K  P    PK  P T  S+  D T      P     P    ++   SP   P    
Sbjct: 1440 PVSLKKAPATSAPKGGPATP-SSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPA 1498

Query: 243  PVYIEMVGNILRDFRKE---------DDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCS 293
            P+    +  ++    KE         D     A     K P    L           +  
Sbjct: 1499 PMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPA--TLAPKEALIPPAMTVP 1556

Query: 294  SQCATPTVPDLDFAKASVPCPPKGLLCDIPP---PFPNLLSHRPPLLVFPPAPVHCSPNS 350
            S   TP +P         P  P       PP   P     +  P  L+ PPA    SP  
Sbjct: 1557 SPKKTPAIP----TPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKE 1612

Query: 351  DESP--LTPLEVTKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPAS--- 405
              +P  +TP    K P              +PS+L       A +  +  A +  AS   
Sbjct: 1613 APTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGL 1672

Query: 406  -------ATPALSSSPPPPSTLYRTQSPHGYP---KSHSTSP----SPVSMGRSLTPLSL 451
                   A   +  +P P ST   T      P   KS +TSP     P +   S  PLS 
Sbjct: 1673 PAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLST 1732

Query: 452  KRPPPY--------------DAVHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGA 497
              P P               DA HS     + P    STP   +     +      +  A
Sbjct: 1733 VAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSA 1792

Query: 498  APG--------------------------GSRSRTPTSPL-----EELTSLF-----SSG 521
            AP                           G    +P+ PL     +EL  L      S G
Sbjct: 1793 APSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPISGG 1852

Query: 522  ---RSLLRKSSSGRRS---------KEPAEKSTEELKVRSHSTEPLPKLDNKE 562
               +S+L    + + +         K+P  K+ +     S S E +P+L+ ++
Sbjct: 1853 VPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEEQD 1905


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 56.2 bits (134), Expect = 9e-08
 Identities = 120/533 (22%), Positives = 179/533 (33%), Gaps = 101/533 (18%)

Query: 102 PQDRLPHP-----CSSGFSVRSQSLHSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTSSE 156
           P  R+P P       S    R +S  S+ G+   SS    R PP KP +       TSS 
Sbjct: 328 PPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPK------RTSSP 381

Query: 157 TVSSTAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRNPNTQLSTSFDETYIKKHG 216
              +   S S   P R    + P           PPPK + +P  Q S    ++ +    
Sbjct: 382 PRKTRRLSPSASPPRRRHRPSPP---------ATPPPKTRHSPTPQQSNRTRKSRVSV-S 431

Query: 217 PRRTS--LPRDSSLSQMGSPAGDPEEEEPVYIEMVGNILRDFRKEDDDQSEAVYEEMKYP 274
           P RTS  + +     +  SP+  P+  +    E   +        D  Q    Y      
Sbjct: 432 PGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQ 491

Query: 275 IFDDLGQDAKCDFD----------------HHSCSSQCA------------------TPT 300
              D G  +  + +                 HS S   +                  +P+
Sbjct: 492 SSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPS 551

Query: 301 VPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDE--SPLTPL 358
            P     ++  P PP       P P P   +  PP     P+P   SP      SP  P 
Sbjct: 552 PPPTRRRRSPSPAPPPRRR-RTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPP- 609

Query: 359 EVTKLPVLENVSYMKQP-AGASPSTLPSHVPGHAKLEKEQAAALGPASATPALS------ 411
                P     S    P   ASPS  P     H+   K++++ +     +P+LS      
Sbjct: 610 -----PKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPV-TKRRSPSLSSKHRKG 663

Query: 412 SSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPS 471
           SSP   +   R+  P+   K HS SP P +   S +P     PP      S    R SPS
Sbjct: 664 SSPSRSTREARSPQPN---KRHSPSPRPRAPQTSSSP-----PPVRRGASSSPQRRQSPS 715

Query: 472 VP-------HSTPRP--------VSQDGAKMVNAAVNTYGA-APGGSRSRTPTSPLE-EL 514
                      TP P         S    + V+++ +  G+  P   +   P SP++ + 
Sbjct: 716 PSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQS 775

Query: 515 TSLFSSGRSLLRKSSSGRRSKEPAEKSTEE--LKVRSHSTEPLPKLDNKERGH 565
            S   S    ++K+ S   S  P   S +E   K +    +   K D K + H
Sbjct: 776 PSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKH 828



 Score = 43.5 bits (101), Expect = 6e-04
 Identities = 105/463 (22%), Positives = 152/463 (32%), Gaps = 78/463 (16%)

Query: 137 RQPPPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEA-SAKPRPHSDEYSKKIPPPKP 195
           R P  +  R PS +   SS        S S     RT++ S  P P   E + ++P P  
Sbjct: 170 RSPRRRKSRSPSPR-RRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSV 228

Query: 196 K-RNPNTQLSTSFDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPEEEEPVYIEMVGNILR 254
           K + P+ Q +TS                   S + ++  P   PE +EP           
Sbjct: 229 KVKEPSVQEATS------------------TSDILKVPKPEPIPEPKEP----------- 259

Query: 255 DFRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTVPDLDFAKASVPCP 314
               E + + E   E+ +        +            S+  + T P       S    
Sbjct: 260 --SPEKNSKKEKEKEKTR-------PRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYS 310

Query: 315 PKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLENVSYMKQ 374
           P+        P P     R P    PP P H    S             PV         
Sbjct: 311 PRRRPSPRRRPSPR---RRTPPRRMPPPPRHRRSRS-------------PVRRRRRSSAS 354

Query: 375 PAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYPKSHS 434
            +G+S S+  S      K   ++ ++  P   T  LS S  PP   +R   P   P    
Sbjct: 355 LSGSSSSSSSSRSRSPPKKPPKRTSS--PPRKTRRLSPSASPPRRRHRPSPPATPPPKTR 412

Query: 435 TSPSPVSMGR---SLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAA 491
            SP+P    R   S   +S  R       H G+  R SPS     P+P   + ++     
Sbjct: 413 HSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPS---PAPKPRKVELSESEEDK 469

Query: 492 VNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEKSTEELKVRSH- 550
                AA    + R      ++ +S   SG S    SS   R K    K+ E  + R H 
Sbjct: 470 GGKMAAADSVQQRRQYRRQNQQSSS--DSGSS---SSSEDERPKRSHVKNGEVGRRRRHS 524

Query: 551 ---STEPLPKLDNKE---RGHHGASSSREPVKAQEWDGTPGPP 587
              S  P P+   KE   RG    S S  P + +    +P PP
Sbjct: 525 PSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRR-SPSPAPP 566


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 113/472 (23%), Positives = 162/472 (34%), Gaps = 56/472 (11%)

Query: 140 PPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRNP 199
           PP  +  P++  +   E + S A       P +T ++    PH +  +   P P P + P
Sbjct: 520 PPSLQTPPASLTTPPLENLPSLAPP-----PLQTASAPLTTPHLE--TPPCPAPCPLQAP 572

Query: 200 NTQLSTSFDETYIKKHGPRRTSLPRDSSLSQMG------SPAGDPEEEEPVYIEMVGNIL 253
            + L+T   ET      P   + P  +S    G      SP   P  + P  +      L
Sbjct: 573 PSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLA-----L 627

Query: 254 RDFRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTVPDLDFAKASVPC 313
              +      +      +  P        A      H   +  + P  P +    +    
Sbjct: 628 PPLQAPPSPPASPPLSPLATP-----SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 682

Query: 314 PPKGLLCDIPPPFPNLLSHRPPLLV--FPPAPVHCSPNSDESPLTPLEVTKLPVLENVSY 371
           PP       P   P  L+  PPL V   PPA    SP++   P  P  +   P+    S 
Sbjct: 683 PPVSPSATPPSQAPPSLA-APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP 741

Query: 372 MKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSP-HGYP 430
              P  +  +T P  VP        Q     PAS   +  + PPP +       P    P
Sbjct: 742 PASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALP 801

Query: 431 KSHSTSP--SPVSMGRSLTPLSLKRPPPY-DAVHSGSLSRSSPSVPHSTP-----RPVSQ 482
              ++ P  +P S   SL    L  PPP    V +  L +  PS P S       RP + 
Sbjct: 802 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 861

Query: 483 DGAKMVNAAVNTYGAAPG--GSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEK 540
                V+    T   APG     SR+P+S L        SG  L   SSS       A  
Sbjct: 862 GPDTSVSGPRLTLALAPGPPPPPSRSPSSTL--------SGPDLAGHSSS-------ATS 906

Query: 541 STEELKVRSHSTE----PLPKLDNKERGHHGASSSREPVKAQEWDGTPGPPV 588
           + EEL+      E      P  D +    H A+ SR P     + G PG P+
Sbjct: 907 TPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPL 958



 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 92/382 (24%), Positives = 134/382 (35%), Gaps = 45/382 (11%)

Query: 140 PPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPR------PHSDEYSKKIPPP 193
           PP P   PS +   S      + A  S  TP      +         PHS        PP
Sbjct: 345 PPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPP 404

Query: 194 KPKRNPNTQLSTSFDETYIKKHGPRRTSLPRDS--SLSQMGSPAGDPEEEEPVYIEMVGN 251
            P    + Q +TS     ++      T  PR +  SL+    PA  P +  P+   +   
Sbjct: 405 SPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLS-- 462

Query: 252 ILRDFRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTVPDLD----FA 307
            L          S AV   +  P+     Q A      HS  +  ++  +P L+     A
Sbjct: 463 -LPASPPLQTSLSPAV-SPLSSPLTIHPLQ-ALSSLASHSPQAPLSSLIMPPLETQSSLA 519

Query: 308 KASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLE 367
             S+  PP  L     PP  NL S  PP L    AP+  +P+ +  P         P+  
Sbjct: 520 PPSLQTPPASLTT---PPLENLPSLAPPPLQTASAPL-TTPHLETPPCP----APCPLQA 571

Query: 368 NVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPH 427
             S +  P   +PS++ +  P        QA    PA A+P L   P PP +   T  P 
Sbjct: 572 PPSPLTTPPPETPSSIATPPP--------QAP---PALASPPLQGLPSPPLSPLATPPPQ 620

Query: 428 GYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGAKM 487
                   +P  +++     P S    PP   + + S    +    H    P S   +  
Sbjct: 621 --------APPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 672

Query: 488 VNAAVNTYGAAPGGSRSRTPTS 509
           V A  +   A+P  S S TP S
Sbjct: 673 VQAPFSP-PASPPVSPSATPPS 693



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 82/301 (27%), Positives = 107/301 (35%), Gaps = 61/301 (20%)

Query: 298 TPTVPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTP 357
           TP  P    A  S P  PKGL    PP          P L     P+  SP +  SP + 
Sbjct: 262 TPRAP----AHPSQP-KPKGLQALRPPQVTPPRKDAAPAL----GPLSSSPLATPSP-SG 311

Query: 358 LEVTKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPP 417
            +   +P  +N       A   P+TLP   P    L      A    SA P+L + P PP
Sbjct: 312 TKARPVPPPDNA------ATPLPATLPPSPP----LATPLPLAPPSPSAPPSLQTLPSPP 361

Query: 418 ST------LYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRP----------------- 454
           +T         T  P   P S  T P P+ +  SLT  SL+ P                 
Sbjct: 362 ATPPSQAPPSMTTPPMQAPPSLQTIP-PIQVPHSLTSPSLQAPPSPLALSSLQATTSLGS 420

Query: 455 PPYDAVHS--------GSLSRSSPSVPHSTP--RPVSQDGAKMVNAAVNTYGAAPGGSRS 504
           P   A HS           S +SPS P STP   P  Q    +  +       +P  S  
Sbjct: 421 PTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPL 480

Query: 505 RTPTS--PLEELTSLFSSG-----RSLLRKSSSGRRSKEPAEKSTEELKVRSHSTEPLPK 557
            +P +  PL+ L+SL S        SL+      + S  P    T    + +   E LP 
Sbjct: 481 SSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPS 540

Query: 558 L 558
           L
Sbjct: 541 L 541



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 61/261 (23%), Positives = 90/261 (34%), Gaps = 29/261 (11%)

Query: 327 PNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLENVS---YMKQPAGASPSTL 383
           P LL+ RPP    PP PV           TP  +  L     V      ++  G   +T+
Sbjct: 22  PGLLTPRPPGSPRPPPPV-----------TPAALRVLGAAGAVGRKPLAERAGGIGGATI 70

Query: 384 PSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYP--KSHSTSPSP-- 439
           P   P          ++  PAS  PA       P     +  P   P   S +T P P  
Sbjct: 71  PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG 130

Query: 440 -----VSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNT 494
                +S   ++        P   A+ +G+   +S   P  TP P     ++     V  
Sbjct: 131 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP-GTPSPAMARRSRAAGTEVGL 189

Query: 495 YGAAPGGSRSRTPT-SPLEELTSLFSSGRSLLRKSSSGRRSKEPAEKSTEELKVRSHSTE 553
              AP  +R R PT  P + ++S  +S  S    S + RR +  A    +    RS S+ 
Sbjct: 190 PRPAP-SARPRPPTEGPRKSVSS--ASEHSTTEPSPAARR-RPSAGGGLQRPASRSLSSS 245

Query: 554 PLPKLDNKERGHHGASSSREP 574
             P       G     + R P
Sbjct: 246 ATPLSSPARSGPSARGTPRAP 266


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 86/321 (26%), Positives = 118/321 (36%), Gaps = 47/321 (14%)

Query: 291  SCSSQCATPTVP---DLDFAKASVPCPPKG---LLCDIPPPFPNLLSHRPPLLVFPPAPV 344
            S S   ATP  P         A  P PP     +L   P   P L S + P+ V  P+  
Sbjct: 1578 SASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSST 1637

Query: 345  HCSPNSDESPLTPLEVTKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPA 404
              +  +  SP+        PVL   S         PS LPS           Q  AL PA
Sbjct: 1638 PGTSLASASPVP----APTPVLAPSSTQTMLPAPVPSPLPSPA-------STQTLALAPA 1686

Query: 405  SATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTP-----LSLKRPPPYDA 459
             A P L  S P  +    T +P G   + + S +P S   SL P     LSL   PP   
Sbjct: 1687 LA-PTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPAS---SLVPTPAQTLSLAPGPPLGP 1742

Query: 460  VHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFS 519
              + SL+ + P  P S   P       +  A+ +    AP   ++ T  SP    T   +
Sbjct: 1743 TQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLT-LSPAPVPTLGPA 1801

Query: 520  SGRSLLRKSSSGRRSKEPAEKSTEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQE 579
            + ++L    +S   ++ PA +++  L V +    PLP              SR PV   E
Sbjct: 1802 AAQTLALAPAS---TQSPASQAS-SLVVSASGAAPLPV----------TMVSRLPVSKDE 1847

Query: 580  WD------GTPGPPVVTSRLG 594
             D      G P PP   +  G
Sbjct: 1848 PDTLTLRSGPPSPPSTATSFG 1868



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 76/319 (23%), Positives = 112/319 (35%), Gaps = 51/319 (15%)

Query: 320  CDIPPPFPNLLSHRPP----LLVFPPAPVHCSPNSDESPLTPLE--VTKLPV-LENVSYM 372
            C  PP      +H PP     LV P +P+   P     P  P+   VT LP+ L   + +
Sbjct: 2499 CTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGP-----PSVPISASVTNLPLGLRPEAEL 2553

Query: 373  KQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPA-----------LSSSPPPPS-TL 420
               A ASP +L   +   A  E    + + P    P            LS +P  PS TL
Sbjct: 2554 CAQALASPESL--ELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTL 2611

Query: 421  YRTQSPHGYPKSHSTSPSPVSM-----------------GRSLTPLSLKRPPPYDAVHSG 463
                 P+G  +    S    ++                 G  L P +    P  + + + 
Sbjct: 2612 EAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEAD 2671

Query: 464  SLSR--SSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSG 521
              S   +    P S+P    Q+      AA +T  +A       +P  P    TS     
Sbjct: 2672 RTSEELTEAKTPTSSPEK-PQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVE- 2729

Query: 522  RSLLRKSSSGRRSKEPAEKSTEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQEWD 581
               +R   +GR  + P  K   +L  R  +     +L  + R   GA+S+  P    E  
Sbjct: 2730 ---IRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVP-GVSETS 2785

Query: 582  GTPGPPVVTSRLGRCSVSP 600
             +PG P V S  G  S  P
Sbjct: 2786 ASPGSPSVRSMSGPESSPP 2804



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 79/319 (24%), Positives = 122/319 (38%), Gaps = 58/319 (18%)

Query: 302  PDLDFAKASVPCPP--KGLLCDIPPPFPNLLSHRP---PLLVFPPAPVHCS---PNSDES 353
            P L  A+A +P P   + LL  +  P P + +  P   PL +  P  V  S   P S   
Sbjct: 1356 PTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPM 1415

Query: 354  PLTPLEVTKLPVLENVSYMKQPAGAS-----PSTLPSHVPGHAKLEKEQAAAL-----GP 403
            P+        PV   VS    P  +S     P+TLP+  P  A L    +A L     GP
Sbjct: 1416 PIPNSSPLASPVSSTVSV---PLSSSLPISVPTTLPA--PASAPLTIPISAPLTVSASGP 1470

Query: 404  A---SATPALS----SSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTP-LSLKRPP 455
            A   S TP L+    ++P PPS           P   S S S +++G +  P LS  + P
Sbjct: 1471 ALLTSVTPPLAPVVPAAPGPPSLA---------PSGASPSASALTLGLATAPSLSSSQTP 1521

Query: 456  PYDAVHSGSLSRSSPSVP--HSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTP-TSPLE 512
                 H   L+ +S  VP  +ST  P         +A  + + +AP  + ++    +P  
Sbjct: 1522 G----HPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPAS 1577

Query: 513  ELTSLFSSGRSLLRKSSSGRRSKEPAEKSTEELKVRSHSTEPLPKLDNKERGHHGASSSR 572
              +   ++  + +    +   +  PA               PLP L          +SS+
Sbjct: 1578 SASQALATPLAPMAAPQTAILAPSPAP-----------PLAPLPVLAPSPGAAPVLASSQ 1626

Query: 573  EPVKAQEWDGTPGPPVVTS 591
             PV       TPG  + ++
Sbjct: 1627 TPVPVMAPSSTPGTSLASA 1645



 Score = 38.9 bits (89), Expect = 0.016
 Identities = 76/304 (25%), Positives = 103/304 (33%), Gaps = 54/304 (17%)

Query: 297  ATPTVPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCS-PNSDESPL 355
            +T T P    A+  VP P        P P P   S    +    P PV    P S  +P+
Sbjct: 2422 STTTPPRCSPARERVPRPA-------PRPRPTPASAPAAIPALVPVPVSAPVPISAPNPI 2474

Query: 356  TPLEVTKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPP 415
            T L V  LP     S +  P  +SP+  P                  P + TP  + +PP
Sbjct: 2475 TILPVHILPSPPPPSQI--PPCSSPACTP------------------PPACTPPPAHTPP 2514

Query: 416  PPSTLYRTQS------PHGYPKSHSTSPSPVSM--GRSLTPLSLKRPPPYDAVHSGSLSR 467
            P  T   T S      P   P S S +  P+ +     L   +L  P   +     S   
Sbjct: 2515 PAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVASSET 2574

Query: 468  SSPS-VPHS-------TPRPVSQDGAKMVNAAVN---TYGAAPGGSRSRTPTSPLEELTS 516
            SS S VP            PVS+    +  +A +     G+ P G     P S      +
Sbjct: 2575 SSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLT 2634

Query: 517  LFSSGRSL-LRKSSSGRRSKEPAEKSTEELKVRSHSTEPLPKLDNKERGHHGASSSREPV 575
            +   G  L L  S S      P+  S E L+      EPL      E      + +  P 
Sbjct: 2635 VLPEGEELPLCVSESNGLELPPSAASDEPLQ------EPLEADRTSEELTEAKTPTSSPE 2688

Query: 576  KAQE 579
            K QE
Sbjct: 2689 KPQE 2692



 Score = 33.1 bits (74), Expect = 0.85
 Identities = 56/217 (25%), Positives = 73/217 (33%), Gaps = 10/217 (4%)

Query: 297  ATPTVPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPL- 355
            A P  P L  + AS       L     P   +  +   PLL+ P +      NS  +P  
Sbjct: 1486 AAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPAC 1545

Query: 356  TPLEVTKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPP 415
            +P+ V    +         PA A  S L         L    A    P +A  A S +PP
Sbjct: 1546 SPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPP 1605

Query: 416  PPSTLYRTQSPHGYP-KSHSTSPSPVSMGRSLTPLSLKR----PPPYDAVHSGSLSRSSP 470
                     SP   P  + S +P PV    S    SL      P P   +   S     P
Sbjct: 1606 LAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLP 1665

Query: 471  S-VPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRT 506
            + VP   P P S     +  A   T G   G S S+T
Sbjct: 1666 APVPSPLPSPASTQTLALAPALAPTLG---GSSPSQT 1699



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 50/187 (26%), Positives = 64/187 (34%), Gaps = 17/187 (9%)

Query: 341  PAPVHCSPNSDESPLTPLEVTKLPVLENVSY------MKQPAGASPSTLPSHVPGHAKLE 394
            P PV    N    P+   E   + V+ N         ++ P G   S  P+  P    L 
Sbjct: 987  PKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSAQPTPGPVPQVLP 1046

Query: 395  KEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTP---LSL 451
                 +  PA      +S PP P  L   Q   G       SP  V  G S  P   LSL
Sbjct: 1047 ASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSL 1106

Query: 452  KRPPP-----YDAVHSGSLSRSSP-SVP--HSTPRPVSQDGAKMVNAAVNTYGAAPGGSR 503
            K  PP       A   GS S   P +VP  ++ P   +   +     A  T   AP  + 
Sbjct: 1107 KPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAP 1166

Query: 504  SRTPTSP 510
             R   SP
Sbjct: 1167 QRLILSP 1173



 Score = 30.4 bits (67), Expect = 5.5
 Identities = 42/160 (26%), Positives = 54/160 (33%), Gaps = 19/160 (11%)

Query: 101  APQDRLPHPCSSGFSVRSQ-SLHSVGGTDDDSSCGS-----------RRQPPPKPKRDPS 148
            AP   LP P    F  R    L   GG   ++  G+           RR  PPK  R P+
Sbjct: 2812 APSSSLPTPPQQPFIARRHIELGVTGGGSPENGDGALLAITPPAVKRRRGRPPKKNRSPA 2871

Query: 149  TKLSTSSETVSSTAASK-SGKTP---ERTEASAKPRPHSDEYSKKIP-PPKPKRNPNTQL 203
                   E  SST   K +G  P     T   A P           P  P+P   PN  L
Sbjct: 2872 DAGRGVDEAPSSTLKGKTNGADPVPGPETLIVADPVLEPQLIPGPQPLGPQPVHRPNPLL 2931

Query: 204  STSFDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPEEEEP 243
            S    E   +   P+   LP   ++S  G    +   + P
Sbjct: 2932 SPV--EKRRRGRPPKARDLPIPGTISSAGDGNSESRTQPP 2969



 Score = 30.4 bits (67), Expect = 5.5
 Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 8/63 (12%)

Query: 323  PPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEV-TKLPVLENVSYMKQPAGASPS 381
            PPP P+ L+  PPLLV P A V        + +T + + T  P  +     K P    PS
Sbjct: 2968 PPPHPSPLTPLPPLLVCPTATV-------ANTVTTVTISTSPPKRKRGRPPKNPPSPRPS 3020

Query: 382  TLP 384
             LP
Sbjct: 3021 QLP 3023


>gi|55750053 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 96/395 (24%), Positives = 124/395 (31%), Gaps = 86/395 (21%)

Query: 103 QDRLPHPCSSGF--SVRSQSLHSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTSSETVSS 160
           +  LP P S     S+  +SL+  G +D        R   P      S +    +++ SS
Sbjct: 93  EQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVE----NDSDSS 148

Query: 161 TAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRNPNTQLSTSFDETYIKKHGPRRT 220
           +  S+    P        P P         PP    R P          T    H P   
Sbjct: 149 SGLSQGPARPYHPPPLFPPSPQ--------PPDSTPRQPEASFEPHPSVTPTGYHAPME- 199

Query: 221 SLPRDSSLSQMGSPAGDPEEEEPVYIEMVGNILRDFRKEDDDQSEAVYEEMKYPIFDDLG 280
             P  S + Q  +P G P     +Y    G +L                    P     G
Sbjct: 200 --PPTSRMFQ--APPGAPPPHPQLYPGGTGGVLSG------------------PPMGPKG 237

Query: 281 QDAKCDFDHHSCSSQCATPTVPDLDFAKASVPCPPKGLLCDIPPPFP---NLLSHRPPLL 337
             A       +   Q   PT P    +  +   PP       PP  P     L   PP  
Sbjct: 238 GGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTK-----PPTTPVGGGNLPSAPPPA 292

Query: 338 VFPPAPVHCSPNSDESPLTPLEVTKLPVLENVSYMKQPAGASPSTLPSHVPGHAKL---- 393
            FP    H +PN    P        L  L N S      GA P  LP H+P    +    
Sbjct: 293 NFP----HVTPNLPPPPA-------LRPLNNASASPPGLGAQP--LPGHLPSPHAMGQGM 339

Query: 394 -------EKEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSL 446
                  EK    A  P S  PA SS+P PP           +P S S+S S  +   S 
Sbjct: 340 GGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMR---------FPYSSSSSSSAAASSSSS 390

Query: 447 TPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVS 481
           +  S   P P         S++ PS PHS P P S
Sbjct: 391 SSSSSASPFP--------ASQALPSYPHSFPPPTS 417



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 110/451 (24%), Positives = 152/451 (33%), Gaps = 96/451 (21%)

Query: 140 PPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPRPHSD---EYSKKIPPPKPK 196
           P  P R P +  S+SS   SS+++S S        +SA P P S     Y    PPP   
Sbjct: 367 PAPPMRFPYSSSSSSSAAASSSSSSSS--------SSASPFPASQALPSYPHSFPPP--- 415

Query: 197 RNPNTQLSTSFDETYIKKHGPRRT--SLPRDSSLSQMGSPAGDPEEEEPVYIEMVGNILR 254
               T LS S          P+ T  SLP  +  SQ   P        P Y  ++ N   
Sbjct: 416 ----TSLSVS-------NQPPKYTQPSLPSQAVWSQGPPPP-------PPYGRLLANSNA 457

Query: 255 D---FRKEDDDQSEAV--------YEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTVPD 303
               F      QS A         + + +        Q  +    HH  S     P  P 
Sbjct: 458 HPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSG----PPPP- 512

Query: 304 LDFAKASVPCPPKGLLCDIPPPF---PNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEV 360
                 + P P +G       P+   P+L S RP    +PP P H  P   +   +    
Sbjct: 513 -----GAFPHPLEGGSSHHAHPYAMSPSLGSLRP----YPPGPAHLPPPHSQVSYSQAGP 563

Query: 361 TKLPVLENVSYMKQPAGASPSTLPSHVP-GHAKLEKEQAAALGPASATPALSSSPPPPST 419
              PV  +       + +S ST     P  H    +    A  P    P +++S    ST
Sbjct: 564 NGPPVSSS-------SNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLST 616

Query: 420 L----------YRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSS 469
           +          Y+T SP G P     +PSP +            PP Y      S    +
Sbjct: 617 VIATVASSPAGYKTASPPGPPPYGKRAPSPGA-------YKTATPPGYKPGSPPSFRTGT 669

Query: 470 PSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSS 529
           P     T  P      K  +  V   G  P    S  P+ P        +SG  L    S
Sbjct: 670 PPGYRGTSPPAGPGTFKPGSPTVGP-GPLPPAGPSGLPSLPPPPAAP--ASGPPL----S 722

Query: 530 SGRRSKEPAEK-STEELKV-RSHSTEPLPKL 558
           + +  +EPAE+  T E  V  + S  P PK+
Sbjct: 723 ATQIKQEPAEEYETPESPVPPARSPSPPPKV 753



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 39/137 (28%), Positives = 47/137 (34%), Gaps = 13/137 (9%)

Query: 107 PHPCSSGFSVRSQSLHSVGGTDDDSSCGSRRQPPPKPK----RDPSTKLSTSSETVSSTA 162
           P   SS  S  S S  S   +    S G +  P P P        S  LST   TV+S+ 
Sbjct: 566 PPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSP 625

Query: 163 ASKSGKTPERTEASAKPRPHSDEYSKKIPPP-KPKRNPNTQLSTSFDETYIKKHGPRRTS 221
           A     +P       K  P    Y    PP  KP   P+ +  T          G R TS
Sbjct: 626 AGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGT--------PPGYRGTS 677

Query: 222 LPRDSSLSQMGSPAGDP 238
            P      + GSP   P
Sbjct: 678 PPAGPGTFKPGSPTVGP 694



 Score = 30.0 bits (66), Expect = 7.2
 Identities = 29/96 (30%), Positives = 38/96 (39%), Gaps = 15/96 (15%)

Query: 100 PAPQDRLPHPCSSGFSVRSQSLHSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTSSETVS 159
           PAP  R P+  SS  S  + S          SS  S   P P  +  PS   S       
Sbjct: 367 PAPPMRFPYSSSSSSSAAASS--------SSSSSSSSASPFPASQALPSYPHSFP----P 414

Query: 160 STAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKP 195
            T+ S S + P+ T+ S    P    +S+  PPP P
Sbjct: 415 PTSLSVSNQPPKYTQPSL---PSQAVWSQGPPPPPP 447


>gi|55750041 atrophin-1 [Homo sapiens]
          Length = 1190

 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 96/395 (24%), Positives = 124/395 (31%), Gaps = 86/395 (21%)

Query: 103 QDRLPHPCSSGF--SVRSQSLHSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTSSETVSS 160
           +  LP P S     S+  +SL+  G +D        R   P      S +    +++ SS
Sbjct: 93  EQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVE----NDSDSS 148

Query: 161 TAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRNPNTQLSTSFDETYIKKHGPRRT 220
           +  S+    P        P P         PP    R P          T    H P   
Sbjct: 149 SGLSQGPARPYHPPPLFPPSPQ--------PPDSTPRQPEASFEPHPSVTPTGYHAPME- 199

Query: 221 SLPRDSSLSQMGSPAGDPEEEEPVYIEMVGNILRDFRKEDDDQSEAVYEEMKYPIFDDLG 280
             P  S + Q  +P G P     +Y    G +L                    P     G
Sbjct: 200 --PPTSRMFQ--APPGAPPPHPQLYPGGTGGVLSG------------------PPMGPKG 237

Query: 281 QDAKCDFDHHSCSSQCATPTVPDLDFAKASVPCPPKGLLCDIPPPFP---NLLSHRPPLL 337
             A       +   Q   PT P    +  +   PP       PP  P     L   PP  
Sbjct: 238 GGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTK-----PPTTPVGGGNLPSAPPPA 292

Query: 338 VFPPAPVHCSPNSDESPLTPLEVTKLPVLENVSYMKQPAGASPSTLPSHVPGHAKL---- 393
            FP    H +PN    P        L  L N S      GA P  LP H+P    +    
Sbjct: 293 NFP----HVTPNLPPPPA-------LRPLNNASASPPGLGAQP--LPGHLPSPHAMGQGM 339

Query: 394 -------EKEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSL 446
                  EK    A  P S  PA SS+P PP           +P S S+S S  +   S 
Sbjct: 340 GGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMR---------FPYSSSSSSSAAASSSSS 390

Query: 447 TPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVS 481
           +  S   P P         S++ PS PHS P P S
Sbjct: 391 SSSSSASPFP--------ASQALPSYPHSFPPPTS 417



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 110/451 (24%), Positives = 152/451 (33%), Gaps = 96/451 (21%)

Query: 140 PPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPRPHSD---EYSKKIPPPKPK 196
           P  P R P +  S+SS   SS+++S S        +SA P P S     Y    PPP   
Sbjct: 367 PAPPMRFPYSSSSSSSAAASSSSSSSS--------SSASPFPASQALPSYPHSFPPP--- 415

Query: 197 RNPNTQLSTSFDETYIKKHGPRRT--SLPRDSSLSQMGSPAGDPEEEEPVYIEMVGNILR 254
               T LS S          P+ T  SLP  +  SQ   P        P Y  ++ N   
Sbjct: 416 ----TSLSVS-------NQPPKYTQPSLPSQAVWSQGPPPP-------PPYGRLLANSNA 457

Query: 255 D---FRKEDDDQSEAV--------YEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTVPD 303
               F      QS A         + + +        Q  +    HH  S     P  P 
Sbjct: 458 HPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSG----PPPP- 512

Query: 304 LDFAKASVPCPPKGLLCDIPPPF---PNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEV 360
                 + P P +G       P+   P+L S RP    +PP P H  P   +   +    
Sbjct: 513 -----GAFPHPLEGGSSHHAHPYAMSPSLGSLRP----YPPGPAHLPPPHSQVSYSQAGP 563

Query: 361 TKLPVLENVSYMKQPAGASPSTLPSHVP-GHAKLEKEQAAALGPASATPALSSSPPPPST 419
              PV  +       + +S ST     P  H    +    A  P    P +++S    ST
Sbjct: 564 NGPPVSSS-------SNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLST 616

Query: 420 L----------YRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSS 469
           +          Y+T SP G P     +PSP +            PP Y      S    +
Sbjct: 617 VIATVASSPAGYKTASPPGPPPYGKRAPSPGA-------YKTATPPGYKPGSPPSFRTGT 669

Query: 470 PSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSS 529
           P     T  P      K  +  V   G  P    S  P+ P        +SG  L    S
Sbjct: 670 PPGYRGTSPPAGPGTFKPGSPTVGP-GPLPPAGPSGLPSLPPPPAAP--ASGPPL----S 722

Query: 530 SGRRSKEPAEK-STEELKV-RSHSTEPLPKL 558
           + +  +EPAE+  T E  V  + S  P PK+
Sbjct: 723 ATQIKQEPAEEYETPESPVPPARSPSPPPKV 753



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 39/137 (28%), Positives = 47/137 (34%), Gaps = 13/137 (9%)

Query: 107 PHPCSSGFSVRSQSLHSVGGTDDDSSCGSRRQPPPKPK----RDPSTKLSTSSETVSSTA 162
           P   SS  S  S S  S   +    S G +  P P P        S  LST   TV+S+ 
Sbjct: 566 PPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSP 625

Query: 163 ASKSGKTPERTEASAKPRPHSDEYSKKIPPP-KPKRNPNTQLSTSFDETYIKKHGPRRTS 221
           A     +P       K  P    Y    PP  KP   P+ +  T          G R TS
Sbjct: 626 AGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGT--------PPGYRGTS 677

Query: 222 LPRDSSLSQMGSPAGDP 238
            P      + GSP   P
Sbjct: 678 PPAGPGTFKPGSPTVGP 694



 Score = 30.0 bits (66), Expect = 7.2
 Identities = 29/96 (30%), Positives = 38/96 (39%), Gaps = 15/96 (15%)

Query: 100 PAPQDRLPHPCSSGFSVRSQSLHSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTSSETVS 159
           PAP  R P+  SS  S  + S          SS  S   P P  +  PS   S       
Sbjct: 367 PAPPMRFPYSSSSSSSAAASS--------SSSSSSSSASPFPASQALPSYPHSFP----P 414

Query: 160 STAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKP 195
            T+ S S + P+ T+ S    P    +S+  PPP P
Sbjct: 415 PTSLSVSNQPPKYTQPSL---PSQAVWSQGPPPPPP 447


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 53/184 (28%), Positives = 69/184 (37%), Gaps = 29/184 (15%)

Query: 311 VPCPPKGL-----LCDIPPPFPNLLSHRPPLLV-----FPPAPVHCSPNSDESPLTPLEV 360
           VP PP  L      C  PPP P  LS  P ++      FPP P    P  +  PL P+  
Sbjct: 833 VPVPPPTLPKQQSFCAKPPPSP--LSPVPSVVKQIASQFPPPPT--PPAMESQPLKPVPA 888

Query: 361 TKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTL 420
              P  ++   +K      PS++P   P       E +    P   +P  +  PPPP T 
Sbjct: 889 NVAP--QSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTA 946

Query: 421 YRTQSPHGYP-KSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRP 479
             T    G P K  S + SP            K+PPP       S  +SS    H  P+ 
Sbjct: 947 SPTPDKSGSPGKKTSKTSSPGG----------KKPPP--TPQRNSSIKSSSGAEHPEPKR 994

Query: 480 VSQD 483
            S D
Sbjct: 995 PSVD 998



 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 94/417 (22%), Positives = 135/417 (32%), Gaps = 67/417 (16%)

Query: 298  TPTVPDLDFAKASVPCPPKGLLCDIPPP---------------------FPNLLSHRPPL 336
            TP V      K  +  PP G++   PPP                      P   +  PPL
Sbjct: 688  TPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPL 747

Query: 337  LVF-------------PPAPVHCSPNSDESPLTPLEVTKLPVLENVSYMKQPAGASPSTL 383
             +              PP P   +P   ++P  PL     P             A P+  
Sbjct: 748  KIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPT 807

Query: 384  PSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMG 443
            P  VP   K     A+ + P+  TP +   P PP TL + QS    P     SP P  + 
Sbjct: 808  PP-VPPAKKQPAFPASYIPPSPPTPPV---PVPPPTLPKQQSFCAKPPPSPLSPVPSVVK 863

Query: 444  RSLTPLSLKRPP------PYDAVHSGSLSRSSPSV-------PHSTPRPVSQDGAKMVNA 490
            +  +       P      P   V +    +S P+V       P S P P S D       
Sbjct: 864  QIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVP-SPDFPPPPPE 922

Query: 491  AVNTYGAAPGGSRSRTPTSPLEELT----SLFSSGRSLLRKSSSGRRSKEPAEKSTEELK 546
            +   +   P       P  P    +       S G+   + SS G +   P  +    +K
Sbjct: 923  SSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIK 982

Query: 547  VRSHSTEPLPK---LDNKERGHHGASSSREPVKAQEWDGTPGPPVVTSRLGRCSVSPTLL 603
              S +  P PK   +D+        + S  P K      T  PP    + G+ ++S   L
Sbjct: 983  SSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKE-----TLPPPAAPPKPGKLNLSGVNL 1037

Query: 604  AGNHSSDLVLERN---SGGGLDHESAWGSQDSQDVFQGALQDTQLPTKDIERTTMMS 657
             G      V  +    SG G D    + S  S   F     +T+LP   IE   + S
Sbjct: 1038 PGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFS 1094



 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 80/347 (23%), Positives = 125/347 (36%), Gaps = 74/347 (21%)

Query: 139  PPPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRN 198
            PPP P   P+          +S    KSG   ++T  ++ P         K PPP P+RN
Sbjct: 928  PPPPPSPVPAPP--PPPPPTASPTPDKSGSPGKKTSKTSSP-------GGKKPPPTPQRN 978

Query: 199  PNTQLSTSFDETYIKKHGPRRTSLPRDSSLSQMGSPA--GDPEEE---------EPVYIE 247
             + + S+  +        P+R S+  DS +S+   PA  G P +E         +P  + 
Sbjct: 979  SSIKSSSGAEHP-----EPKRPSV--DSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLN 1031

Query: 248  MVGNILRDFRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTVPDLDFA 307
            + G  L    ++    ++A       P+    G+D+  +F      S    P        
Sbjct: 1032 LSGVNLPGVLQQGCVSAKA-------PVLSGRGKDSVVEFPSPPSDSDFPPPP------P 1078

Query: 308  KASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNS-------------DESP 354
            +  +P PP     +IP  F    S  P + V  P P   S  S             D + 
Sbjct: 1079 ETELPLPP----IEIPAVFSGNTS--PKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTR 1132

Query: 355  LTPLEVTKLPVLENV----------SYMKQP---AGASPSTLPSHVPGHAKLEKEQAAAL 401
            LT  E+++ P +  V          S   QP   A  + +     +  H  L    + A 
Sbjct: 1133 LTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRA- 1191

Query: 402  GPASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTP 448
               +AT    + PPPP  L   Q   GY  SH +  + +  G    P
Sbjct: 1192 -EPTATMDDMALPPPPPELLSDQQKAGYGGSHISGYATLRRGPPPAP 1237



 Score = 37.4 bits (85), Expect = 0.045
 Identities = 51/208 (24%), Positives = 74/208 (35%), Gaps = 31/208 (14%)

Query: 309 ASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLEN 368
           AS P PP       PPP P      PP    PP P   +P++  +    ++ + +  L+N
Sbjct: 621 ASQPSPPLP-----PPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQN 675

Query: 369 VSYMKQPAGA--SPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSP 426
            S   Q +GA   P T P            Q+ ++ P    P     PPPP        P
Sbjct: 676 AS---QHSGALFKPPTPP----------VMQSQSVKPQILVPPNGVVPPPP-----PPPP 717

Query: 427 HGYPKSHSTSPSPVSMGRSLTPLSLKRPP--PYDAVHSGSLSRSSPSVPHSTPRPVSQDG 484
              P S      P     SL   S   PP   +   H   ++  +P  P   P P+    
Sbjct: 718 PPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQA 777

Query: 485 AK----MVNAAVNTYGAAPGGSRSRTPT 508
                  + A  +T   AP  +++  PT
Sbjct: 778 PPKPLVTIPAPTSTKTVAPVVTQAAPPT 805


>gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]
          Length = 987

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 117/520 (22%), Positives = 170/520 (32%), Gaps = 72/520 (13%)

Query: 47  DRLRNETNLAYLKEKNEKRRRQEEAIKRIGGEVG--RGHEGSYVGKHFRMGFMTMPAPQD 104
           D    ET L+ LKEK +KR  +EE    + G+    R H+ S  G       +    P  
Sbjct: 40  DPCAKETVLSALKEKKKKRTVEEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVASGVPAS 99

Query: 105 RLPHPCSSGFSVRSQS----LHSVGGTDDDSS-CGSRRQPPPKPKRDPSTKLSTSSETVS 159
            +P P S    + SQS    L+    +   SS  G+     P   R+  T   +S+  +S
Sbjct: 100 FVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYTSGIPSSSRNAITSSYSSTRGIS 159

Query: 160 -------------STAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRNPNTQLSTS 206
                        S+ AS   +TPER     +        S   P    K    +Q   +
Sbjct: 160 QLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADK---ESQGEKA 216

Query: 207 FDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPEEEEPVYIEMVGNILRDFRKEDDDQSEA 266
            D T  KK      S P  S   +           E + +     +      ED D  + 
Sbjct: 217 ADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKK 276

Query: 267 VYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTVPDLDFA--KASVPCPPKGLLCDIPP 324
              +      +D     K D   +S +    T T P   F    A+   PP  LL     
Sbjct: 277 ASLQWFNQALED-----KSDAASNSVTETPPT-TQPSFTFTLPAAATASPPTSLLAPSTN 330

Query: 325 PFPNLLS--HRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLENVSYMKQPAGASPST 382
           P    L     PP L  PP P      + E+   P   + LP          P G S S 
Sbjct: 331 PLLESLKKMQTPPSL--PPCPESAGAATTEALSPPKTPSLLP----------PLGLSQS- 377

Query: 383 LPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLY-RTQSPHGYPKSHSTSPSPVS 441
                              GP    P+ S    PP+TL     +P   P + + +P  + 
Sbjct: 378 -------------------GPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQ 418

Query: 442 MGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGG 501
              +  P +   P P  A     L  +  + P S   P +   + M          AP  
Sbjct: 419 AETATKPQATSAPSP--APKQSFLFGTQNTSPSSPAAPAASSASPMFKPIF----TAPPK 472

Query: 502 SRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEKS 541
           S    PT P   +T+   S  SL   +S+   + +P   S
Sbjct: 473 SEKEGPTPPGPSVTATAPSSSSLPTTTSTTAPTFQPVFSS 512


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 73/279 (26%), Positives = 100/279 (35%), Gaps = 53/279 (18%)

Query: 314 PPKGLLCDIPPPFPNLLSHR---PPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLENVS 370
           PP+     +PPP P++ S     PP +   P P+  SP++  SP  P             
Sbjct: 161 PPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVP------------- 207

Query: 371 YMKQPAGASPSTLPSHVPGHAKLEKEQAAALG-------PASATPALSSSPPPPSTLYRT 423
               P   SP   P   PG+      +  ALG       P S++   S+ PP P T  R 
Sbjct: 208 --GGPRQPSPGPTPPPFPGN------RGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRA 259

Query: 424 QSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQD 483
                 P      P PV    S+   ++  PPP           + P VP STPRP +  
Sbjct: 260 LDDKPPP-----PPPPVGNRPSIHREAVPPPPP---------QNNKPPVP-STPRPSASS 304

Query: 484 GAKMVNAAVNTYGAAP----GGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAE 539
            A       +  G  P          TP  P   L SL SS   L     SG     P+E
Sbjct: 305 QAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNL-SLSSSTPPLPSPGRSGPLPPPPSE 363

Query: 540 KSTEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQ 578
           +    ++     + PLP      R  +G++S   P   Q
Sbjct: 364 RPPPPVRDPPGRSGPLPPPPPVSR--NGSTSRALPATPQ 400



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 52/179 (29%), Positives = 69/179 (38%), Gaps = 37/179 (20%)

Query: 311 VPCPPKGLLCDIPPPFPNLLSHRPPL---LVFPPAPVHCSPNSDESPLTPLEVTKLPVLE 367
           +P  P   L D PPP P  + +RP +    V PP P +  P    +P  P   ++ P   
Sbjct: 252 LPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTP-RPSASSQAP--- 307

Query: 368 NVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSS------PPPPSTLY 421
                  P+   P  LP    G+ +  +     L  +S+TP L S       PPPPS   
Sbjct: 308 --PPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPS--- 362

Query: 422 RTQSPHGYPKSHSTSPSPV--SMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPR 478
                          P PV    GRS  PL    PPP     +GS SR+ P+ P    R
Sbjct: 363 ------------ERPPPPVRDPPGRS-GPL----PPPPPVSRNGSTSRALPATPQLPSR 404



 Score = 37.0 bits (84), Expect = 0.059
 Identities = 60/224 (26%), Positives = 80/224 (35%), Gaps = 28/224 (12%)

Query: 412 SSPP--PPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKR--PPPYDAVHSGSLSR 467
           S PP  PP     +  P   P      P P    RS  P   +   PPP   V  GS   
Sbjct: 124 SRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDV--GSKPD 181

Query: 468 SSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSR--SRTPTSPLEELTSLFSSGRSLL 525
           S P    STPRP+        +  V      PGG R  S  PT P        + G   +
Sbjct: 182 SIPPPVPSTPRPIQSSPHNRGSPPV------PGGPRQPSPGPTPPPFPGNRGTALGGGSI 235

Query: 526 RK---SSSGRRSKEPAEKSTEELKVRSHSTEPLPKLDNKERGHHGA------SSSREPV- 575
           R+   SSS   S  P    T    +      P P + N+   H  A       +++ PV 
Sbjct: 236 RQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVP 295

Query: 576 ---KAQEWDGTPGPPVVTSRLGRCSVSPTLLAGNHSSDLVLERN 616
              +       P PP   SR G   + P+  +GN  +  + +RN
Sbjct: 296 STPRPSASSQAPPPPPPPSRPGPPPLPPS-SSGNDETPRLPQRN 338



 Score = 36.6 bits (83), Expect = 0.077
 Identities = 58/217 (26%), Positives = 71/217 (32%), Gaps = 39/217 (17%)

Query: 323 PPPFP--------------NLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLEN 368
           PPPFP              + LS   P    PP P   S   D+ P  P           
Sbjct: 219 PPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPP----------- 267

Query: 369 VSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSS-SPPPPSTLYRTQSPH 427
                 P G  PS     VP       +      P++  P+ SS +PPPP    R   P 
Sbjct: 268 ----PPPVGNRPSIHREAVPPPPPQNNKPPV---PSTPRPSASSQAPPPPPPPSRPGPPP 320

Query: 428 GYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGAKM 487
             P S     +P    R+L+ LS   PP      SG L    P  P   P P  +D    
Sbjct: 321 LPPSSSGNDETPRLPQRNLS-LSSSTPPLPSPGRSGPL----PPPPSERPPPPVRDPPGR 375

Query: 488 VNAAVNTYGAAPGGSRSRT-PTSPLEELTSLFSSGRS 523
                     +  GS SR  P +P     S   S RS
Sbjct: 376 SGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRS 412


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 73/279 (26%), Positives = 100/279 (35%), Gaps = 53/279 (18%)

Query: 314 PPKGLLCDIPPPFPNLLSHR---PPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLENVS 370
           PP+     +PPP P++ S     PP +   P P+  SP++  SP  P             
Sbjct: 161 PPEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVP------------- 207

Query: 371 YMKQPAGASPSTLPSHVPGHAKLEKEQAAALG-------PASATPALSSSPPPPSTLYRT 423
               P   SP   P   PG+      +  ALG       P S++   S+ PP P T  R 
Sbjct: 208 --GGPRQPSPGPTPPPFPGN------RGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRA 259

Query: 424 QSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQD 483
                 P      P PV    S+   ++  PPP           + P VP STPRP +  
Sbjct: 260 LDDKPPP-----PPPPVGNRPSIHREAVPPPPP---------QNNKPPVP-STPRPSASS 304

Query: 484 GAKMVNAAVNTYGAAP----GGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAE 539
            A       +  G  P          TP  P   L SL SS   L     SG     P+E
Sbjct: 305 QAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNL-SLSSSTPPLPSPGRSGPLPPPPSE 363

Query: 540 KSTEELKVRSHSTEPLPKLDNKERGHHGASSSREPVKAQ 578
           +    ++     + PLP      R  +G++S   P   Q
Sbjct: 364 RPPPPVRDPPGRSGPLPPPPPVSR--NGSTSRALPATPQ 400



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 52/179 (29%), Positives = 69/179 (38%), Gaps = 37/179 (20%)

Query: 311 VPCPPKGLLCDIPPPFPNLLSHRPPL---LVFPPAPVHCSPNSDESPLTPLEVTKLPVLE 367
           +P  P   L D PPP P  + +RP +    V PP P +  P    +P  P   ++ P   
Sbjct: 252 LPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTP-RPSASSQAP--- 307

Query: 368 NVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSS------PPPPSTLY 421
                  P+   P  LP    G+ +  +     L  +S+TP L S       PPPPS   
Sbjct: 308 --PPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPS--- 362

Query: 422 RTQSPHGYPKSHSTSPSPV--SMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPR 478
                          P PV    GRS  PL    PPP     +GS SR+ P+ P    R
Sbjct: 363 ------------ERPPPPVRDPPGRS-GPL----PPPPPVSRNGSTSRALPATPQLPSR 404



 Score = 37.0 bits (84), Expect = 0.059
 Identities = 60/224 (26%), Positives = 80/224 (35%), Gaps = 28/224 (12%)

Query: 412 SSPP--PPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKR--PPPYDAVHSGSLSR 467
           S PP  PP     +  P   P      P P    RS  P   +   PPP   V  GS   
Sbjct: 124 SRPPLLPPGGRSTSAKPFSPPSGPGRFPVPSPGHRSGPPEPQRNRMPPPRPDV--GSKPD 181

Query: 468 SSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSR--SRTPTSPLEELTSLFSSGRSLL 525
           S P    STPRP+        +  V      PGG R  S  PT P        + G   +
Sbjct: 182 SIPPPVPSTPRPIQSSPHNRGSPPV------PGGPRQPSPGPTPPPFPGNRGTALGGGSI 235

Query: 526 RK---SSSGRRSKEPAEKSTEELKVRSHSTEPLPKLDNKERGHHGA------SSSREPV- 575
           R+   SSS   S  P    T    +      P P + N+   H  A       +++ PV 
Sbjct: 236 RQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVP 295

Query: 576 ---KAQEWDGTPGPPVVTSRLGRCSVSPTLLAGNHSSDLVLERN 616
              +       P PP   SR G   + P+  +GN  +  + +RN
Sbjct: 296 STPRPSASSQAPPPPPPPSRPGPPPLPPS-SSGNDETPRLPQRN 338



 Score = 36.6 bits (83), Expect = 0.077
 Identities = 58/217 (26%), Positives = 71/217 (32%), Gaps = 39/217 (17%)

Query: 323 PPPFP--------------NLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLEN 368
           PPPFP              + LS   P    PP P   S   D+ P  P           
Sbjct: 219 PPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPP----------- 267

Query: 369 VSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSS-SPPPPSTLYRTQSPH 427
                 P G  PS     VP       +      P++  P+ SS +PPPP    R   P 
Sbjct: 268 ----PPPVGNRPSIHREAVPPPPPQNNKPPV---PSTPRPSASSQAPPPPPPPSRPGPPP 320

Query: 428 GYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGAKM 487
             P S     +P    R+L+ LS   PP      SG L    P  P   P P  +D    
Sbjct: 321 LPPSSSGNDETPRLPQRNLS-LSSSTPPLPSPGRSGPL----PPPPSERPPPPVRDPPGR 375

Query: 488 VNAAVNTYGAAPGGSRSRT-PTSPLEELTSLFSSGRS 523
                     +  GS SR  P +P     S   S RS
Sbjct: 376 SGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRS 412


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 59/229 (25%), Positives = 85/229 (37%), Gaps = 24/229 (10%)

Query: 323  PPPF---PNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLENVSYMKQPAGAS 379
            PPP    P  L+H PPL    P P   +    + P++P  V   PV       K     +
Sbjct: 1195 PPPAEPPPTDLAHLPPL----PPPEGEARKPAKPPVSPKPVLTQPV------PKLQGSPT 1244

Query: 380  PSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSP 439
            P++    +PG    E ++A    P    P     PPPP+     ++  G P S S  PSP
Sbjct: 1245 PTSKKVPLPGPGSPEVKRAHGTPP----PVSPKPPPPPTAPKPVKAVAGLP-SGSAGPSP 1299

Query: 440  VSMGRSLTPLSLKRPPPYDAVHSGSLSRS-SPS-----VPHSTPRPVSQDGAKMVNAAVN 493
                    P +L +PP        S ++  SP      VP   PR  +   A        
Sbjct: 1300 APSPARQPPAALAKPPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPAP 1359

Query: 494  TYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEKST 542
              GA+PG S  +        L +   +    +R+  +       AEKST
Sbjct: 1360 PEGASPGDSARQKLEETSACLAAALQAVEEKIRQEDAQGPRDSAAEKST 1408



 Score = 33.5 bits (75), Expect = 0.65
 Identities = 38/127 (29%), Positives = 42/127 (33%), Gaps = 14/127 (11%)

Query: 385  SHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGR 444
            S   G  +L      A  P +    L   PPP     +   P   PK   T P P   G 
Sbjct: 1183 SEQAGPPELPPPPPPAEPPPTDLAHLPPLPPPEGEARKPAKPPVSPKPVLTQPVPKLQG- 1241

Query: 445  SLTPLSLKRPPPYDAVHSGSLSRSSPSV--PHSTPRPVSQDGAKMVNA--AVNTYGAAPG 500
            S TP S K P P            SP V   H TP PVS        A   V      P 
Sbjct: 1242 SPTPTSKKVPLP---------GPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKAVAGLPS 1292

Query: 501  GSRSRTP 507
            GS   +P
Sbjct: 1293 GSAGPSP 1299


>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
            sapiens]
          Length = 1130

 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 75/310 (24%), Positives = 115/310 (37%), Gaps = 35/310 (11%)

Query: 139  PPPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRN 198
            PPP     P     T   T S    +K  + PE   A+  P P         PPP P   
Sbjct: 800  PPPPSGATPPPIAPTGPPTASPPVPAK--EEPEELPAAPGPLPPPP------PPPPPVPG 851

Query: 199  PNTQLSTSF-DETYIKKHGPRRTSLPRDSSLSQMGSP--AGDPEEEEPVYIEMVGNILRD 255
            P T        E      GP   +L  D ++  + S     + EEEE    E       D
Sbjct: 852  PVTLPPPQLVPEGTPGGGGP--PALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEED 909

Query: 256  FRKEDDDQSEAVYEEMKYPI-----FDDLGQDAKCDFDHHSCSSQCATPTVPDLDFAKAS 310
            F +E++D+ E   EE +        F++   + + + +      +     V DL+F  A 
Sbjct: 910  FEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAG 969

Query: 311  VPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLENVS 370
                  G + +  PP P L    PP L  P +P    P  +  P   LEV +    E   
Sbjct: 970  ------GEVEEGAPPPPTL----PPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEE--- 1016

Query: 371  YMKQPAGASPSTLPSHVPGHAKLEKE-QAAALGPASATPALSSSPPPPSTLYRTQSPHGY 429
              ++ A  +P+  P  +P   ++E+E ++ A GP      +   P  P TL   ++  G 
Sbjct: 1017 --ERGADTAPTLAPEALPSQGEVEREGESPAAGPPPQE-LVEEEPSAPPTLLEEETEDGS 1073

Query: 430  PKSHSTSPSP 439
             K      +P
Sbjct: 1074 DKVQPPPETP 1083


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 50.8 bits (120), Expect = 4e-06
 Identities = 76/258 (29%), Positives = 93/258 (36%), Gaps = 48/258 (18%)

Query: 322 IPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLENVSYMKQPAGASPS 381
           +PPPF       PPL   PP  +   P S   P+ P     LP    V     P    P 
Sbjct: 516 MPPPFVPYSQMPPPLPTMPPPVL---PPSLPPPVMP---PALPA--TVPPPGMPPPVMPP 567

Query: 382 TLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVS 441
           +LP+ VP         +A   P    P+LSS+ PPP        P   P   ST+P PV 
Sbjct: 568 SLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPPP-----VLPP---PSLSSTAPPPV- 618

Query: 442 MGRSLTPLSLKRPPP----------------YDAVHSGSLSRSS--PSVPHST--PRPVS 481
               L PLS   PPP                   V   S S+SS  P  P     P PVS
Sbjct: 619 --MPLPPLSSATPPPGIPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVS 676

Query: 482 QDGAKMVNAAVNTYGAAPGGS-RSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEK 540
              A           A P     S+ P S      S FSS + L      G  S  P++ 
Sbjct: 677 FGSAPPTTYHPPLQSAGPSEQVNSKAPLSKSALPYSSFSSDQGL------GESSAAPSQP 730

Query: 541 ST--EELKVRSHSTEPLP 556
            T  +++ VRS    P P
Sbjct: 731 ITAVKDMPVRSGGLLPDP 748



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 55/244 (22%), Positives = 79/244 (32%), Gaps = 24/244 (9%)

Query: 331 SHRPPLLVFPPAPV---HCSP----NSDESPLTP----------LEVTKLPVLENVSYMK 373
           SH PP  V PP PV     SP    +S  +P  P            + +L  L+ +   +
Sbjct: 12  SHYPPPPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMHQKQ 71

Query: 374 QPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQSPHGYPKSH 433
                 P  LP   P             G     P     PP P+  Y+ Q  + +   H
Sbjct: 72  MQCVLQPHHLPP--PPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLH 129

Query: 434 STSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPS-VPHSTPRPVSQDGAKMVNAAV 492
                P      L P+ L+ PP    V  GS    S S +P   P P             
Sbjct: 130 HQRDGP----PGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLP 185

Query: 493 NTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRRSKEPAEKSTEELKVRSHST 552
               +      S++  +P    +S  SS +S L  S S   S + +     +   +S   
Sbjct: 186 PAQPSPSQSPPSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLL 245

Query: 553 EPLP 556
            P P
Sbjct: 246 APPP 249



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 59/213 (27%), Positives = 77/213 (36%), Gaps = 33/213 (15%)

Query: 299 PTVPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESP-LTP 357
           P +P   +     P PP      +PPP    LS++           H     D  P L P
Sbjct: 90  PVMPGGGYGDWQPPPPP------MPPPPGPALSYQKQQQYKHQMLHH---QRDGPPGLVP 140

Query: 358 LEVTKLPVLENV---SYM--KQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSS 412
           +E+   P    V   SYM   Q     P   PS+ P  +       A   P+ + P+ S 
Sbjct: 141 MELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSY 200

Query: 413 SPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGS--LSRSSP 470
             P PS          Y  S S+S S +S  +S  P S   P      HS S  L+   P
Sbjct: 201 LAPTPS----------YSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPP 250

Query: 471 SVPHSTPRPVSQD----GAKMVNAAVNTYGAAP 499
           S P      V Q+    GAK  N +     AAP
Sbjct: 251 SAPPGNKTTVQQEPLESGAK--NKSTEQQQAAP 281



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 47/221 (21%), Positives = 73/221 (33%), Gaps = 47/221 (21%)

Query: 312 PCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSD------ESPLTPLEVTKLPV 365
           P PP      +PPP P  L    P   +  +    +P+S       E  L  L+  +   
Sbjct: 15  PPPP------VPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFREQHLAQLQQLQQMH 68

Query: 366 LENVSYMKQPAGASPSTLPSH--VPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRT 423
            + +  + QP    P  LP    +PG            G     P     PP P+  Y+ 
Sbjct: 69  QKQMQCVLQPHHLPPPPLPPPPVMPG---------GGYGDWQPPPPPMPPPPGPALSYQK 119

Query: 424 QSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSL------------------ 465
           Q  + +   H     P      L P+ L+ PP    V  GS                   
Sbjct: 120 QQQYKHQMLHHQRDGPPG----LVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYY 175

Query: 466 --SRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRS 504
             + S P +P + P P     ++   A   +Y ++   S+S
Sbjct: 176 PPTSSQPYLPPAQPSPSQSPPSQSYLAPTPSYSSSSSSSQS 216


>gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]
          Length = 984

 Score = 50.4 bits (119), Expect = 5e-06
 Identities = 129/564 (22%), Positives = 186/564 (32%), Gaps = 81/564 (14%)

Query: 47  DRLRNETNLAYLKEKNEKRRRQEEAIKRIGGEVG--RGHEGSYVGKHFRMGFMTMPAPQD 104
           D    ET L+ LKEK +KR  +EE    + G+    R H+ S  G       +    P  
Sbjct: 40  DPCAKETVLSALKEKEKKRTVEEEDQIFLDGQENKRRRHDSSGSGHSAFEPLVANGVPAS 99

Query: 105 RLPHPCSSGFSVRSQS----LHSVGGTDDDSS-CGSRRQPPPKPKRDPSTKLSTSSETVS 159
            +P P S    + SQS    L+    +   SS  G+     P   R+  T   +S+  +S
Sbjct: 100 FVPKPGSLKRGLNSQSSDDHLNKRSRSSSMSSLTGAYASGIPSSSRNAITSSYSSTRGIS 159

Query: 160 -------------STAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRNPNTQLSTS 206
                        S+ AS   +TPER     +        S   P    +    +Q   +
Sbjct: 160 QLWKRNGPSSSPFSSPASSRSQTPERPAKKIREEELCHHSSSSTPLAADR---ESQGEKA 216

Query: 207 FDETYIKKHGPRRTSLPRDSSLSQMGSPAGDPEEEEPVYIEMVGNILRDFRKEDDDQSEA 266
            D T  KK      S P  S   +           E + +     +      ED D  + 
Sbjct: 217 ADTTPRKKQNSNSQSTPGSSGQRKRKVQLLPSRRGEQLTLPPPPQLGYSITAEDLDLEKK 276

Query: 267 VYEEMKYPIFDDLGQDAKCDFDHHSCSSQCATPTVPDLDFA----KASVPCPPKGLLCDI 322
              +      +D    A         +S   TP +    F      A+   PP  LL   
Sbjct: 277 ASLQWFNQALEDKSDAAS--------NSVTETPPITQPSFTFTLPAAAPASPPTSLLAPS 328

Query: 323 PPPFPNLLS--HRPPLLVFPPAPVHCSPNSDESPLTPLEVTKLPVLENVSYMKQPAGASP 380
             P    L     PP L  PP P      + E+   P   + LP          P G S 
Sbjct: 329 TNPLLESLKKMQTPPSL--PPCPESAGAATTEALSPPKTPSLLP----------PLGLSQ 376

Query: 381 STLPSHVPGHAKLEKEQAAALG--PA-SATPALSSSPPP------PSTLYRTQSPHGYPK 431
           S  P  +P  +   K     LG  PA S  PA  +  PP       +    T +P   PK
Sbjct: 377 SGPPGLLPSPSFDSKPPTTLLGLIPAPSMVPATDTKAPPTLQAETATKPQATSAPSPAPK 436

Query: 432 ------SHSTSP-SPVSMGRSLTPLSLK-------------RPPPYDAVHSGSLSRSSPS 471
                 + +TSP SP +   S  P   K               PP  +V + + S SS  
Sbjct: 437 QSFLFGTQNTSPSSPAAPAASSAPPMFKPIFTAPPKSEKEGPTPPGPSVTATAPSSSSLP 496

Query: 472 VPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLF---SSGRSLLRKS 528
              ST  P  Q     +    +    AP   ++ TP +       LF   +S  S +   
Sbjct: 497 TTTSTTAPTFQPVFSSMGPPASVPLPAPFFKQTTTPATAPTTTAPLFTGLASATSAVAPI 556

Query: 529 SSGRRSKEPAEKSTEELKVRSHST 552
           +S   S + A K      + S S+
Sbjct: 557 TSASPSTDSASKPAFGFGINSVSS 580


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 55/199 (27%), Positives = 70/199 (35%), Gaps = 39/199 (19%)

Query: 310 SVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPA-------PVHCSPNSDESPLTPLEVTK 362
           S P PP      IPPP P+    +PP    PP        P H  P+  + P  P + + 
Sbjct: 54  SGPKPP------IPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSS 107

Query: 363 LPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALSSSPPPPSTLYR 422
            PV+          G++P    S  P           +  P  + P  + +PPP  T   
Sbjct: 108 KPVVAQGPGPAPGVGSAPPASSSAPPA------TPPTSGAPPGSGPGPTPTPPPAVT--- 158

Query: 423 TQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQ 482
             +P G P      P+P S G   TP     PPP  A   G      P  P   P P   
Sbjct: 159 -SAPPGAPP-----PTPPSSGVPTTPPQAGGPPPPPAAVPG----PGPG-PKQGPGPGGP 207

Query: 483 DGAKMVNAAVNTYGAAPGG 501
            G KM        G  PGG
Sbjct: 208 KGGKMPG------GPKPGG 220



 Score = 37.0 bits (84), Expect = 0.059
 Identities = 33/127 (25%), Positives = 40/127 (31%), Gaps = 12/127 (9%)

Query: 388 PGHAKLEKEQAAALGPASATPALSSSPPPPSTLYRT----QSPHGYPKSHSTSPSPVSMG 443
           PG    +       GP  + P     PPPP    +     Q P   P  H   P P    
Sbjct: 36  PGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQ 95

Query: 444 RSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSR 503
           +   P     PPP D+          P+    +  P S        A   T GA PG   
Sbjct: 96  QQQPP-----PPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPP---ATPPTSGAPPGSGP 147

Query: 504 SRTPTSP 510
             TPT P
Sbjct: 148 GPTPTPP 154


>gi|189011568 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 58/203 (28%), Positives = 85/203 (41%), Gaps = 25/203 (12%)

Query: 372  MKQPAGASPSTLPS-----HVPG--HAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQ 424
            MKQP  A+  ++       H+PG  ++       +  GP   TPA S SP    T   T 
Sbjct: 2213 MKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPA-SKSPSEGQTA--TT 2269

Query: 425  SPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTP--RPVSQ 482
            SP G   S  +  SPV+   S    S K P       SGS   S+PS P   P  RP+  
Sbjct: 2270 SPRGAKPSVKSELSPVARQTSQIGGSSKAPS-----RSGSRD-STPSRPAQQPLSRPIQS 2323

Query: 483  DGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRR-SKEPAEKS 541
             G   ++   N  G +P    S+ P +      S  SSG   +  +S GR+ S++   K 
Sbjct: 2324 PGRNSISPGRN--GISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQ 2381

Query: 542  TEELKVRSHSTEPLPKLDNKERG 564
            T      S +   +P+ ++  +G
Sbjct: 2382 TG----LSKNASSIPRSESASKG 2400


>gi|189011566 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 58/203 (28%), Positives = 85/203 (41%), Gaps = 25/203 (12%)

Query: 372  MKQPAGASPSTLPS-----HVPG--HAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQ 424
            MKQP  A+  ++       H+PG  ++       +  GP   TPA S SP    T   T 
Sbjct: 2213 MKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPA-SKSPSEGQTA--TT 2269

Query: 425  SPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTP--RPVSQ 482
            SP G   S  +  SPV+   S    S K P       SGS   S+PS P   P  RP+  
Sbjct: 2270 SPRGAKPSVKSELSPVARQTSQIGGSSKAPS-----RSGSRD-STPSRPAQQPLSRPIQS 2323

Query: 483  DGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRR-SKEPAEKS 541
             G   ++   N  G +P    S+ P +      S  SSG   +  +S GR+ S++   K 
Sbjct: 2324 PGRNSISPGRN--GISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQ 2381

Query: 542  TEELKVRSHSTEPLPKLDNKERG 564
            T      S +   +P+ ++  +G
Sbjct: 2382 TG----LSKNASSIPRSESASKG 2400


>gi|53759122 adenomatous polyposis coli [Homo sapiens]
          Length = 2843

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 58/203 (28%), Positives = 85/203 (41%), Gaps = 25/203 (12%)

Query: 372  MKQPAGASPSTLPS-----HVPG--HAKLEKEQAAALGPASATPALSSSPPPPSTLYRTQ 424
            MKQP  A+  ++       H+PG  ++       +  GP   TPA S SP    T   T 
Sbjct: 2213 MKQPLQANMPSISRGRTMIHIPGVRNSSSSTSPVSKKGPPLKTPA-SKSPSEGQTA--TT 2269

Query: 425  SPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPPYDAVHSGSLSRSSPSVPHSTP--RPVSQ 482
            SP G   S  +  SPV+   S    S K P       SGS   S+PS P   P  RP+  
Sbjct: 2270 SPRGAKPSVKSELSPVARQTSQIGGSSKAPS-----RSGSRD-STPSRPAQQPLSRPIQS 2323

Query: 483  DGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSGRSLLRKSSSGRR-SKEPAEKS 541
             G   ++   N  G +P    S+ P +      S  SSG   +  +S GR+ S++   K 
Sbjct: 2324 PGRNSISPGRN--GISPPNKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQMSQQNLTKQ 2381

Query: 542  TEELKVRSHSTEPLPKLDNKERG 564
            T      S +   +P+ ++  +G
Sbjct: 2382 TG----LSKNASSIPRSESASKG 2400


>gi|64084766 fidgetin [Homo sapiens]
          Length = 759

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 68/287 (23%), Positives = 96/287 (33%), Gaps = 32/287 (11%)

Query: 293 SSQCATPTVPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFP-PAPVHCSPNSD 351
           SS C + TVP L     S    P      +   +    S   P L  P P+P+H S    
Sbjct: 165 SSTCGSHTVPSLHAGLPSQEYAPGYNGSYLHSTYS---SQPAPALPSPHPSPLHSSGLLQ 221

Query: 352 ESPLTPLEVTKLPVLENVSYMKQPAGASPSTLPSHVPGHAKLEKEQAAALGPASATPALS 411
             P  P     +P     S +   +  S S  P    G         +   P  A     
Sbjct: 222 PPPPPPPPPALVPGYNGTSNLSSYSYPSASYPPQTAVG---------SGYSPGGA----- 267

Query: 412 SSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPL-----------SLKRPPPYDAV 460
             PPPPS    +  P   P   +T P     G  LTP+           SLKR   Y A 
Sbjct: 268 --PPPPSAYLPSGIPAPTPLPPTTVPGYTYQGHGLTPIAPSALTNSSASSLKRKAFYMA- 324

Query: 461 HSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSS 520
             G +  S  +  +   R       +M + +++      G  RS   +S   + T    S
Sbjct: 325 GQGDMDSSYGNYSYGQQRSTQSPMYRMPDNSISNTNRGNGFDRSAETSSLAFKPTKQLMS 384

Query: 521 GRSLLRKSSSGRRSKEPAEKSTEELKVRSHSTEPLPKLDNKERGHHG 567
                + SS   R+  P   ST +  + S S+E   K  +     HG
Sbjct: 385 SEQQRKFSSQSSRALTPPSYSTAKNSLGSRSSESFGKYTSPVMSEHG 431



 Score = 30.8 bits (68), Expect = 4.2
 Identities = 32/124 (25%), Positives = 43/124 (34%), Gaps = 29/124 (23%)

Query: 78  EVGRGHEGSYVGKHFRMGFMTMPAPQDRLPHPCSSGFSVRSQSLHSVGGTDDDSSCGSRR 137
           E   G+ GSY+       + + PAP    PHP           LHS G            
Sbjct: 184 EYAPGYNGSYL----HSTYSSQPAPALPSPHP---------SPLHSSG----------LL 220

Query: 138 QPPPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASA------KPRPHSDEYSKKIP 191
           QPPP P   P+     +  +  S+ +  S   P +T   +       P P S      IP
Sbjct: 221 QPPPPPPPPPALVPGYNGTSNLSSYSYPSASYPPQTAVGSGYSPGGAPPPPSAYLPSGIP 280

Query: 192 PPKP 195
            P P
Sbjct: 281 APTP 284


>gi|38787970 tensin like C1 domain containing phosphatase isoform 3
           [Homo sapiens]
          Length = 1285

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 69/261 (26%), Positives = 93/261 (35%), Gaps = 57/261 (21%)

Query: 364 PVLENVSYMKQPAGASPSTLPSH--VPGHAKLEKEQAAALGPASATPALSS----SPPPP 417
           P L   SY     GA PS  P++  VP       E      P + +P   S    SPP P
Sbjct: 660 PALVTYSY----GGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYP 715

Query: 418 STL---YRTQSPHG---YP-KSHSTSPSPVSMGRSLTPLSLKRPP---------PYDAVH 461
            +    Y   +  G   YP   H  S  P++   SL P+S +  P         P DA  
Sbjct: 716 QSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPC 775

Query: 462 SGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSG 521
           S S   S PS P  T  PV                     +R +   SP    T   S G
Sbjct: 776 SASSELSGPSTPLHTSSPVQ----------------GKESTRRQDTRSPTSAPTQRLSPG 819

Query: 522 RSL--LRKSSSGRRSKEPAEKSTEELKVRSHSTEPLPKLDN---KER---GHHGASSSRE 573
            +L  + ++ +G+  + P+    E L     S    P   +   +ER   GH   +S R 
Sbjct: 820 EALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRS 879

Query: 574 PV-------KAQEWDGTPGPP 587
           PV       +   W G  GPP
Sbjct: 880 PVPTTLPGLRHAPWQGPRGPP 900



 Score = 35.0 bits (79), Expect = 0.22
 Identities = 38/148 (25%), Positives = 51/148 (34%), Gaps = 5/148 (3%)

Query: 95  GFMTMPAPQDRLPHPCSSGFSVRSQSLHSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTS 154
           G  T+P      P   SS  S  S  LH+        S  +RRQ    P   P+ +LS  
Sbjct: 762 GHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKES--TRRQDTRSPTSAPTQRLSPG 819

Query: 155 SETVSSTAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRNPNTQLSTSFDETYIKK 214
            E +   + + +GK PE    S          S   PP  P   P  + S          
Sbjct: 820 -EALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQ-ERSPGGHSDGASP 877

Query: 215 HGPRRTSLPRDSSLSQMGSPAGDPEEEE 242
             P  T+LP        G P G P+  +
Sbjct: 878 RSPVPTTLPGLRHAPWQG-PRGPPDSPD 904



 Score = 30.0 bits (66), Expect = 7.2
 Identities = 17/54 (31%), Positives = 22/54 (40%), Gaps = 9/54 (16%)

Query: 403 PASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPP 456
           P   TP   S  PPP  +    S  G+  + +T P+  S G         RPPP
Sbjct: 365 PPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPG---------RPPP 409


>gi|38787957 tensin like C1 domain containing phosphatase isoform 2
            [Homo sapiens]
          Length = 1409

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 69/261 (26%), Positives = 93/261 (35%), Gaps = 57/261 (21%)

Query: 364  PVLENVSYMKQPAGASPSTLPSH--VPGHAKLEKEQAAALGPASATPALSS----SPPPP 417
            P L   SY     GA PS  P++  VP       E      P + +P   S    SPP P
Sbjct: 784  PALVTYSY----GGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYP 839

Query: 418  STL---YRTQSPHG---YP-KSHSTSPSPVSMGRSLTPLSLKRPP---------PYDAVH 461
             +    Y   +  G   YP   H  S  P++   SL P+S +  P         P DA  
Sbjct: 840  QSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPC 899

Query: 462  SGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSG 521
            S S   S PS P  T  PV                     +R +   SP    T   S G
Sbjct: 900  SASSELSGPSTPLHTSSPVQ----------------GKESTRRQDTRSPTSAPTQRLSPG 943

Query: 522  RSL--LRKSSSGRRSKEPAEKSTEELKVRSHSTEPLPKLDN---KER---GHHGASSSRE 573
             +L  + ++ +G+  + P+    E L     S    P   +   +ER   GH   +S R 
Sbjct: 944  EALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRS 1003

Query: 574  PV-------KAQEWDGTPGPP 587
            PV       +   W G  GPP
Sbjct: 1004 PVPTTLPGLRHAPWQGPRGPP 1024



 Score = 35.0 bits (79), Expect = 0.22
 Identities = 38/148 (25%), Positives = 51/148 (34%), Gaps = 5/148 (3%)

Query: 95   GFMTMPAPQDRLPHPCSSGFSVRSQSLHSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTS 154
            G  T+P      P   SS  S  S  LH+        S  +RRQ    P   P+ +LS  
Sbjct: 886  GHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKES--TRRQDTRSPTSAPTQRLSPG 943

Query: 155  SETVSSTAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRNPNTQLSTSFDETYIKK 214
             E +   + + +GK PE    S          S   PP  P   P  + S          
Sbjct: 944  -EALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQ-ERSPGGHSDGASP 1001

Query: 215  HGPRRTSLPRDSSLSQMGSPAGDPEEEE 242
              P  T+LP        G P G P+  +
Sbjct: 1002 RSPVPTTLPGLRHAPWQG-PRGPPDSPD 1028



 Score = 30.0 bits (66), Expect = 7.2
 Identities = 17/54 (31%), Positives = 22/54 (40%), Gaps = 9/54 (16%)

Query: 403 PASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPP 456
           P   TP   S  PPP  +    S  G+  + +T P+  S G         RPPP
Sbjct: 489 PPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPG---------RPPP 533


>gi|38787941 tensin like C1 domain containing phosphatase isoform 1
            [Homo sapiens]
          Length = 1419

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 69/261 (26%), Positives = 93/261 (35%), Gaps = 57/261 (21%)

Query: 364  PVLENVSYMKQPAGASPSTLPSH--VPGHAKLEKEQAAALGPASATPALSS----SPPPP 417
            P L   SY     GA PS  P++  VP       E      P + +P   S    SPP P
Sbjct: 794  PALVTYSY----GGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYP 849

Query: 418  STL---YRTQSPHG---YP-KSHSTSPSPVSMGRSLTPLSLKRPP---------PYDAVH 461
             +    Y   +  G   YP   H  S  P++   SL P+S +  P         P DA  
Sbjct: 850  QSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPC 909

Query: 462  SGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSSG 521
            S S   S PS P  T  PV                     +R +   SP    T   S G
Sbjct: 910  SASSELSGPSTPLHTSSPVQ----------------GKESTRRQDTRSPTSAPTQRLSPG 953

Query: 522  RSL--LRKSSSGRRSKEPAEKSTEELKVRSHSTEPLPKLDN---KER---GHHGASSSRE 573
             +L  + ++ +G+  + P+    E L     S    P   +   +ER   GH   +S R 
Sbjct: 954  EALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRS 1013

Query: 574  PV-------KAQEWDGTPGPP 587
            PV       +   W G  GPP
Sbjct: 1014 PVPTTLPGLRHAPWQGPRGPP 1034



 Score = 35.0 bits (79), Expect = 0.22
 Identities = 38/148 (25%), Positives = 51/148 (34%), Gaps = 5/148 (3%)

Query: 95   GFMTMPAPQDRLPHPCSSGFSVRSQSLHSVGGTDDDSSCGSRRQPPPKPKRDPSTKLSTS 154
            G  T+P      P   SS  S  S  LH+        S  +RRQ    P   P+ +LS  
Sbjct: 896  GHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKES--TRRQDTRSPTSAPTQRLSPG 953

Query: 155  SETVSSTAASKSGKTPERTEASAKPRPHSDEYSKKIPPPKPKRNPNTQLSTSFDETYIKK 214
             E +   + + +GK PE    S          S   PP  P   P  + S          
Sbjct: 954  -EALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQ-ERSPGGHSDGASP 1011

Query: 215  HGPRRTSLPRDSSLSQMGSPAGDPEEEE 242
              P  T+LP        G P G P+  +
Sbjct: 1012 RSPVPTTLPGLRHAPWQG-PRGPPDSPD 1038



 Score = 30.0 bits (66), Expect = 7.2
 Identities = 17/54 (31%), Positives = 22/54 (40%), Gaps = 9/54 (16%)

Query: 403 PASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKRPPP 456
           P   TP   S  PPP  +    S  G+  + +T P+  S G         RPPP
Sbjct: 499 PPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPG---------RPPP 543


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.127    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,295,153
Number of Sequences: 37866
Number of extensions: 2141163
Number of successful extensions: 14848
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 119
Number of HSP's successfully gapped in prelim test: 1112
Number of HSP's that attempted gapping in prelim test: 10575
Number of HSP's gapped (non-prelim): 4709
length of query: 669
length of database: 18,247,518
effective HSP length: 109
effective length of query: 560
effective length of database: 14,120,124
effective search space: 7907269440
effective search space used: 7907269440
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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