Search of human proteins with 239753216

Search of human proteins with 239753216

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239753216 PREDICTED: similar to immunoglobulin superfamily,
member 3 [Homo sapiens]
         (376 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239753216 PREDICTED: similar to immunoglobulin superfamily, m...   763   0.0  
gi|55953135 immunoglobulin superfamily, member 3 isoform 2 [Homo...   686   0.0  
gi|55953133 immunoglobulin superfamily, member 3 isoform 1 [Homo...   676   0.0  
gi|157694489 immunoglobulin superfamily, member 2 [Homo sapiens]      194   8e-50
gi|16445029 immunoglobulin superfamily, member 8 [Homo sapiens]       124   2e-28
gi|41152506 prostaglandin F2 receptor negative regulator [Homo s...    93   3e-19
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]             42   0.001
gi|31377806 polymeric immunoglobulin receptor precursor [Homo sa...    41   0.002
gi|33519481 neural cell adhesion molecule 2 precursor [Homo sapi...    39   0.006
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]                    39   0.008
gi|51988914 fibroblast growth factor receptor-like 1 precursor [...    39   0.008
gi|51988910 fibroblast growth factor receptor-like 1 precursor [...    39   0.008
gi|51988912 fibroblast growth factor receptor-like 1 precursor [...    39   0.008
gi|13489095 sialoadhesin precursor [Homo sapiens]                      36   0.049
gi|27894328 interleukin 1 receptor-like 1 isoform 2 precursor [H...    35   0.11 
gi|27894324 interleukin 1 receptor-like 1 isoform 1 precursor [H...    35   0.11 
gi|118572606 hemicentin 1 [Homo sapiens]                               35   0.14 
gi|45594240 limbic system-associated membrane protein [Homo sapi...    35   0.14 
gi|239753266 PREDICTED: hypothetical protein [Homo sapiens]            34   0.19 
gi|238624147 neuroplastin isoform c precursor [Homo sapiens]           34   0.19 
gi|6912646 neuroplastin isoform b precursor [Homo sapiens]             34   0.19 
gi|169215606 PREDICTED: similar to immunoglobulin superfamily, m...    34   0.25 
gi|239746626 PREDICTED: similar to KIAA0466 protein [Homo sapiens]     34   0.25 
gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo ...    34   0.25 
gi|118197279 sialic acid binding Ig-like lectin 7 isoform 2 [Hom...    34   0.25 
gi|18079321 V-set and transmembrane domain containing 2 like [Ho...    34   0.25 
gi|254028242 fibroblast growth factor receptor 3 isoform 3 precu...    33   0.32 
gi|4503711 fibroblast growth factor receptor 3 isoform 1 precurs...    33   0.32 
gi|7657361 contactin 6 [Homo sapiens]                                  33   0.32 
gi|24111244 MAM domain containing glycosylphosphatidylinositol a...    33   0.32 

>gi|239753216 PREDICTED: similar to immunoglobulin superfamily,
           member 3 [Homo sapiens]
          Length = 376

 Score =  763 bits (1971), Expect = 0.0
 Identities = 376/376 (100%), Positives = 376/376 (100%)

Query: 1   MWLRVLVQTLYIEGPLAPCKVGEKPVEVISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRT 60
           MWLRVLVQTLYIEGPLAPCKVGEKPVEVISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRT
Sbjct: 1   MWLRVLVQTLYIEGPLAPCKVGEKPVEVISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRT 60

Query: 61  TFRLTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLET 120
           TFRLTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLET
Sbjct: 61  TFRLTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLET 120

Query: 121 EKRLHMVGEPVEFRCIPEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARG 180
           EKRLHMVGEPVEFRCIPEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARG
Sbjct: 121 EKRLHMVGEPVEFRCIPEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARG 180

Query: 181 QLNVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVLPL 240
           QLNVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVLPL
Sbjct: 181 QLNVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVLPL 240

Query: 241 ESSISVEVASNASVILEGEDLRFSCSVRMAGRPQGRFSVIWQLVDRQNRRSDIMWLDRDG 300
           ESSISVEVASNASVILEGEDLRFSCSVRMAGRPQGRFSVIWQLVDRQNRRSDIMWLDRDG
Sbjct: 241 ESSISVEVASNASVILEGEDLRFSCSVRMAGRPQGRFSVIWQLVDRQNRRSDIMWLDRDG 300

Query: 301 TVQPGSSYWERSSFGSVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRVVDGEWQIV 360
           TVQPGSSYWERSSFGSVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRVVDGEWQIV
Sbjct: 301 TVQPGSSYWERSSFGSVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRVVDGEWQIV 360

Query: 361 GERRASTPISIIALGE 376
           GERRASTPISIIALGE
Sbjct: 361 GERRASTPISIIALGE 376


>gi|55953135 immunoglobulin superfamily, member 3 isoform 2 [Homo
           sapiens]
          Length = 1194

 Score =  686 bits (1771), Expect = 0.0
 Identities = 341/355 (96%), Positives = 345/355 (97%)

Query: 20  KVGEKPVEVISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYC 79
           KVGEKPVEVISLSRDFMLHS SEYA RQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYC
Sbjct: 187 KVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYC 246

Query: 80  EAAEWIQNPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRCIPEA 139
           EAAEWIQ+PDGSWYAMTRKRSEGAVVNVQPT+KEFTVRLETEKRLH VGEPVEFRCI EA
Sbjct: 247 EAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEFRCILEA 306

Query: 140 QNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLNVAKESDSVFVLKIYHL 199
           QNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQL VAKESDSVFVLKIYHL
Sbjct: 307 QNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFVLKIYHL 366

Query: 200 RQEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVASNASVILEGE 259
           RQEDSGKYNCRVTEREKTVTGEFIDKESK PKNIPIIVLPL+SSISVEVASNASVILEGE
Sbjct: 367 RQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIVLPLKSSISVEVASNASVILEGE 426

Query: 260 DLRFSCSVRMAGRPQGRFSVIWQLVDRQNRRSDIMWLDRDGTVQPGSSYWERSSFGSVQM 319
           DLRFSCSVR AGRPQGRFSVIWQLVDRQNRRS+IMWLDRDGTVQPGSSYWERSSFG VQM
Sbjct: 427 DLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSNIMWLDRDGTVQPGSSYWERSSFGGVQM 486

Query: 320 EQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRVVDGEWQIVGERRASTPISIIAL 374
           EQVQPNSFSLGIFNSRKEDEGQYECHVTEWVR VDGEWQIVGERRASTPISI AL
Sbjct: 487 EQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRAVDGEWQIVGERRASTPISITAL 541



 Score = 99.0 bits (245), Expect = 6e-21
 Identities = 73/350 (20%), Positives = 133/350 (38%), Gaps = 42/350 (12%)

Query: 62   FRLTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETE 121
            F LT+   + SD G +YC   EW+ +P+ +WY +  + S    V V+  +    +     
Sbjct: 765  FSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLRLSQAQG 824

Query: 122  KRLHMVGEPVEFRCIPEAQNVPDRYFAVSWAF------NSSLIATMGPNAVPVLNSEFAH 175
                +    V+  C+   +        V W            +A +  +A      + A 
Sbjct: 825  NLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHPERETVARLSRDATFHYGEQAAK 884

Query: 176  REARGQLNVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPI 235
               +G+L++   S  V+ L I ++  +DSG Y+C V E   + +G +  +         +
Sbjct: 885  NNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAGQTAL 944

Query: 236  IVLPLESSISVEVASNASVILEGEDLRFSCSVRMAGRPQGRFSVIWQLV----------- 284
             V+  ++S+ V+     + + E    +  CS+        RF+V W  +           
Sbjct: 945  TVMRPDASLQVDTVVPNATVSEKAAFQLDCSIVSRSSQDSRFAVAWYSLRTKAGGKRSSP 1004

Query: 285  --------------------DRQNRRSDIMWLDRDGTVQPGSSYWERSSFGSVQMEQVQP 324
                                D    R+ ++ +  D    P  S WE    G ++ +++ P
Sbjct: 1005 GLEEQEEEREEEEEEDDDDDDDPTERTALLSVGPDAVFGPEGSPWE----GRLRFQRLSP 1060

Query: 325  NSFSLGIFNSRKEDEGQYECHVTEWVRVVDGEWQIVGERRASTPISIIAL 374
              + L +  +  +D G Y CHV EW+     EW  + E   S PI I  L
Sbjct: 1061 VLYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLTEEE-SAPIGIRVL 1109



 Score = 98.2 bits (243), Expect = 1e-20
 Identities = 82/342 (23%), Positives = 146/342 (42%), Gaps = 30/342 (8%)

Query: 43  YAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEG 102
           Y  R   G++ ++++   +  L I  LQ  D GE+ C      +   GS+ A        
Sbjct: 84  YTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTPSTDKQYFGSYSAKMN----- 138

Query: 103 AVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRCIPEAQNVPDRYFAVSWAFNSSLIATMG 162
             + V P   + T   +T  R+    +P+E  C   ++ +   + +V+W     L   +G
Sbjct: 139 --LVVIPDSLQTTAMPQTLHRVEQ--DPLELTCEVASETIQHSHLSVAW-----LRQKVG 189

Query: 163 PNAVPVL----------NSEFAHREARGQLNVAKESDSVFVLKIYHLRQEDSGKYNCRVT 212
              V V+          +SE+A R++ G++ + K   + F L I+HL+  D G++ C   
Sbjct: 190 EKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAA 249

Query: 213 EREKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVASNASVILEGEDLRFSCSVRMAGR 272
           E  +   G +     K  +   + V P +   +V + +   +   GE + F C +     
Sbjct: 250 EWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEFRCILEAQNV 309

Query: 273 PQGRFSVIWQLVDRQNRRSDIMWLDRDGTVQPGSSYWERSSFGSVQMEQVQPNSFSLGIF 332
           P   F+V W         S I  +  +      S +  R + G +++ +   + F L I+
Sbjct: 310 PDRYFAVSWAF-----NSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFVLKIY 364

Query: 333 NSRKEDEGQYECHVTEWVRVVDGEWQIVGERRASTPISIIAL 374
           + R+ED G+Y C VTE  + V GE+ I  E +    I II L
Sbjct: 365 HLRQEDSGKYNCRVTEREKTVTGEF-IDKESKRPKNIPIIVL 405



 Score = 92.4 bits (228), Expect = 6e-19
 Identities = 77/348 (22%), Positives = 144/348 (41%), Gaps = 20/348 (5%)

Query: 28  VISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQN 87
           ++ L RD  +  GS Y  R S G V+++++   +F L IF+ +  D+G++ C   EW++ 
Sbjct: 460 IMWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRA 519

Query: 88  PDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRCIPEAQNVPDRYF 147
            DG W  +  +R+    +++   E  F V   +        +  + +CI +         
Sbjct: 520 VDGEWQIVGERRAS-TPISITALEMGFAVTAISRTPGVTYSDSFDLQCIIKPHYPAWVPV 578

Query: 148 AVSWAFNS-------SLIATMGPNAVPVLNSEFAHREARGQLNVAKESDSVFVLKIYHLR 200
           +V+W F          L+       V   +   + R  R  +  A+ S++V  L I    
Sbjct: 579 SVTWRFQPVGTVEFHDLVTFTRDGGVQWGDRSSSFR-TRTAIEKAESSNNVR-LSISRAS 636

Query: 201 QEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVASNASVILEGED 260
             ++GKY C      K     +     +    + I VL   + + V  +     ++E + 
Sbjct: 637 DTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKP 696

Query: 261 LRFSCSVRMAGRPQGRFSVIWQLVDRQNRRSD-----IMWLDRDGTVQPGSSYWERSSFG 315
           ++ +CSV+        F+V+W +    ++ SD     I+    +   + G+   E     
Sbjct: 697 IQLNCSVKSQTSQNSHFAVLWYV----HKPSDADGKLILKTTHNSAFEYGTYAEEEGLRA 752

Query: 316 SVQMEQ-VQPNSFSLGIFNSRKEDEGQYECHVTEWVRVVDGEWQIVGE 362
            +Q E+ V    FSL +  +   D G Y CHV EW+   +  W  + E
Sbjct: 753 RLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAE 800



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 72/307 (23%), Positives = 120/307 (39%), Gaps = 16/307 (5%)

Query: 63  RLTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEGAVVNV-QPTEKEFTVRLETE 121
           RL+I     ++ G++ C A  W +N + +W  +  + S    + V QP  K   +++   
Sbjct: 629 RLSISRASDTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTK---LQVSKS 685

Query: 122 KRLHMVGE--PVEFRCIPEAQNVPDRYFAVSWAFNS------SLIATMGPNAVPVLNSEF 173
           KR   + E  P++  C  ++Q   + +FAV W  +        LI     N+     +  
Sbjct: 686 KRTLTLVENKPIQLNCSVKSQTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYA 745

Query: 174 AHREARGQLNVAKE-SDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKN 232
                R +L   +  S  +F L +      DSG Y C V E   +    +     +    
Sbjct: 746 EEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGR 805

Query: 233 IPIIVLPLESSISVEVASNASVILEGEDLRFSCSVRMAGRPQGRFSVIWQLVDRQNR--R 290
             + V   +S + +  A     +LE   ++  C V        +  V W  V + N   R
Sbjct: 806 TEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVVLNRTSITSQLMVEW-FVWKPNHPER 864

Query: 291 SDIMWLDRDGTVQPGSSYWERSSFGSVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWV 350
             +  L RD T   G    + +  G + +E   P  + L I N   +D G Y CHV EW+
Sbjct: 865 ETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWL 924

Query: 351 RVVDGEW 357
               G W
Sbjct: 925 PSPSGMW 931



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 56/260 (21%), Positives = 94/260 (36%), Gaps = 40/260 (15%)

Query: 28   VISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQN 87
            V  LSRD   H G + A     G + L+      +RL I ++   D G + C   EW+ +
Sbjct: 867  VARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPS 926

Query: 88   PDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMVGEPVEFR--CIPEAQNVPDR 145
            P G WY      +    + V     + +++++T      V E   F+  C   +++  D 
Sbjct: 927  PSGMWYKRAEDTAGQTALTVM--RPDASLQVDTVVPNATVSEKAAFQLDCSIVSRSSQDS 984

Query: 146  YFAVSWAFNSSLIATMGPNAVPVLNSEFAHREA--------------------------- 178
             FAV+W   S      G  + P L  +   RE                            
Sbjct: 985  RFAVAW--YSLRTKAGGKRSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVGPDAVF 1042

Query: 179  -------RGQLNVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPK 231
                    G+L   + S  ++ L +     +D+G Y+C V E   +   E+     +   
Sbjct: 1043 GPEGSPWEGRLRFQRLSPVLYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLTEEESA 1102

Query: 232  NIPIIVLPLESSISVEVASN 251
             I I VL    ++   + SN
Sbjct: 1103 PIGIRVLDTSPTLQSIICSN 1122



 Score = 35.8 bits (81), Expect = 0.065
 Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 1/89 (1%)

Query: 257 EGEDLRFSCSVRMAGRPQGRFSVIWQLVDRQNRRSDIMWLDRDGTVQPGSSYWERSSFGS 316
           EG  +   C+V     P  + +  W +    +   ++  +    +  P + Y +R   G 
Sbjct: 34  EGSHITIWCNVSGYQGPSEQ-NFQWSIYLPSSPEREVQIVSTMDSSFPYAIYTQRVRGGK 92

Query: 317 VQMEQVQPNSFSLGIFNSRKEDEGQYECH 345
           + +E+VQ NS  L I + +  D G+YECH
Sbjct: 93  IFIERVQGNSTLLHITDLQARDAGEYECH 121


>gi|55953133 immunoglobulin superfamily, member 3 isoform 1 [Homo
           sapiens]
          Length = 1214

 Score =  676 bits (1744), Expect = 0.0
 Identities = 342/375 (91%), Positives = 345/375 (92%), Gaps = 20/375 (5%)

Query: 20  KVGEKPVEVISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYC 79
           KVGEKPVEVISLSRDFMLHS SEYA RQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYC
Sbjct: 187 KVGEKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYC 246

Query: 80  EAAEWIQNPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRCIPEA 139
           EAAEWIQ+PDGSWYAMTRKRSEGAVVNVQPT+KEFTVRLETEKRLH VGEPVEFRCI EA
Sbjct: 247 EAAEWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEFRCILEA 306

Query: 140 QNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLNVAKESDSVFVLKIYHL 199
           QNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQL VAKESDSVFVLKIYHL
Sbjct: 307 QNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFVLKIYHL 366

Query: 200 RQEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVLP-------------------- 239
           RQEDSGKYNCRVTEREKTVTGEFIDKESK PKNIPIIVLP                    
Sbjct: 367 RQEDSGKYNCRVTEREKTVTGEFIDKESKRPKNIPIIVLPLTDNWVVKVPQHHQLLSQGH 426

Query: 240 LESSISVEVASNASVILEGEDLRFSCSVRMAGRPQGRFSVIWQLVDRQNRRSDIMWLDRD 299
           LESSISVEVASNASVILEGEDLRFSCSVR AGRPQGRFSVIWQLVDRQNRRS+IMWLDRD
Sbjct: 427 LESSISVEVASNASVILEGEDLRFSCSVRTAGRPQGRFSVIWQLVDRQNRRSNIMWLDRD 486

Query: 300 GTVQPGSSYWERSSFGSVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRVVDGEWQI 359
           GTVQPGSSYWERSSFG VQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVR VDGEWQI
Sbjct: 487 GTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRAVDGEWQI 546

Query: 360 VGERRASTPISIIAL 374
           VGERRASTPISI AL
Sbjct: 547 VGERRASTPISITAL 561



 Score = 99.0 bits (245), Expect = 6e-21
 Identities = 73/350 (20%), Positives = 133/350 (38%), Gaps = 42/350 (12%)

Query: 62   FRLTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETE 121
            F LT+   + SD G +YC   EW+ +P+ +WY +  + S    V V+  +    +     
Sbjct: 785  FSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGRTEVTVKQPDSRLRLSQAQG 844

Query: 122  KRLHMVGEPVEFRCIPEAQNVPDRYFAVSWAF------NSSLIATMGPNAVPVLNSEFAH 175
                +    V+  C+   +        V W            +A +  +A      + A 
Sbjct: 845  NLSVLETRQVQLECVVLNRTSITSQLMVEWFVWKPNHPERETVARLSRDATFHYGEQAAK 904

Query: 176  REARGQLNVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPI 235
               +G+L++   S  V+ L I ++  +DSG Y+C V E   + +G +  +         +
Sbjct: 905  NNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPSPSGMWYKRAEDTAGQTAL 964

Query: 236  IVLPLESSISVEVASNASVILEGEDLRFSCSVRMAGRPQGRFSVIWQLV----------- 284
             V+  ++S+ V+     + + E    +  CS+        RF+V W  +           
Sbjct: 965  TVMRPDASLQVDTVVPNATVSEKAAFQLDCSIVSRSSQDSRFAVAWYSLRTKAGGKRSSP 1024

Query: 285  --------------------DRQNRRSDIMWLDRDGTVQPGSSYWERSSFGSVQMEQVQP 324
                                D    R+ ++ +  D    P  S WE    G ++ +++ P
Sbjct: 1025 GLEEQEEEREEEEEEDDDDDDDPTERTALLSVGPDAVFGPEGSPWE----GRLRFQRLSP 1080

Query: 325  NSFSLGIFNSRKEDEGQYECHVTEWVRVVDGEWQIVGERRASTPISIIAL 374
              + L +  +  +D G Y CHV EW+     EW  + E   S PI I  L
Sbjct: 1081 VLYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLTEEE-SAPIGIRVL 1129



 Score = 98.2 bits (243), Expect = 1e-20
 Identities = 82/342 (23%), Positives = 146/342 (42%), Gaps = 30/342 (8%)

Query: 43  YAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEG 102
           Y  R   G++ ++++   +  L I  LQ  D GE+ C      +   GS+ A        
Sbjct: 84  YTQRVRGGKIFIERVQGNSTLLHITDLQARDAGEYECHTPSTDKQYFGSYSAKMN----- 138

Query: 103 AVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRCIPEAQNVPDRYFAVSWAFNSSLIATMG 162
             + V P   + T   +T  R+    +P+E  C   ++ +   + +V+W     L   +G
Sbjct: 139 --LVVIPDSLQTTAMPQTLHRVEQ--DPLELTCEVASETIQHSHLSVAW-----LRQKVG 189

Query: 163 PNAVPVL----------NSEFAHREARGQLNVAKESDSVFVLKIYHLRQEDSGKYNCRVT 212
              V V+          +SE+A R++ G++ + K   + F L I+HL+  D G++ C   
Sbjct: 190 EKPVEVISLSRDFMLHSSSEYAQRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAA 249

Query: 213 EREKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVASNASVILEGEDLRFSCSVRMAGR 272
           E  +   G +     K  +   + V P +   +V + +   +   GE + F C +     
Sbjct: 250 EWIQDPDGSWYAMTRKRSEGAVVNVQPTDKEFTVRLETEKRLHTVGEPVEFRCILEAQNV 309

Query: 273 PQGRFSVIWQLVDRQNRRSDIMWLDRDGTVQPGSSYWERSSFGSVQMEQVQPNSFSLGIF 332
           P   F+V W         S I  +  +      S +  R + G +++ +   + F L I+
Sbjct: 310 PDRYFAVSWAF-----NSSLIATMGPNAVPVLNSEFAHREARGQLKVAKESDSVFVLKIY 364

Query: 333 NSRKEDEGQYECHVTEWVRVVDGEWQIVGERRASTPISIIAL 374
           + R+ED G+Y C VTE  + V GE+ I  E +    I II L
Sbjct: 365 HLRQEDSGKYNCRVTEREKTVTGEF-IDKESKRPKNIPIIVL 405



 Score = 92.4 bits (228), Expect = 6e-19
 Identities = 77/348 (22%), Positives = 144/348 (41%), Gaps = 20/348 (5%)

Query: 28  VISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQN 87
           ++ L RD  +  GS Y  R S G V+++++   +F L IF+ +  D+G++ C   EW++ 
Sbjct: 480 IMWLDRDGTVQPGSSYWERSSFGGVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRA 539

Query: 88  PDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRCIPEAQNVPDRYF 147
            DG W  +  +R+    +++   E  F V   +        +  + +CI +         
Sbjct: 540 VDGEWQIVGERRAS-TPISITALEMGFAVTAISRTPGVTYSDSFDLQCIIKPHYPAWVPV 598

Query: 148 AVSWAFNS-------SLIATMGPNAVPVLNSEFAHREARGQLNVAKESDSVFVLKIYHLR 200
           +V+W F          L+       V   +   + R  R  +  A+ S++V  L I    
Sbjct: 599 SVTWRFQPVGTVEFHDLVTFTRDGGVQWGDRSSSFR-TRTAIEKAESSNNVR-LSISRAS 656

Query: 201 QEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVASNASVILEGED 260
             ++GKY C      K     +     +    + I VL   + + V  +     ++E + 
Sbjct: 657 DTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTKLQVSKSKRTLTLVENKP 716

Query: 261 LRFSCSVRMAGRPQGRFSVIWQLVDRQNRRSD-----IMWLDRDGTVQPGSSYWERSSFG 315
           ++ +CSV+        F+V+W +    ++ SD     I+    +   + G+   E     
Sbjct: 717 IQLNCSVKSQTSQNSHFAVLWYV----HKPSDADGKLILKTTHNSAFEYGTYAEEEGLRA 772

Query: 316 SVQMEQ-VQPNSFSLGIFNSRKEDEGQYECHVTEWVRVVDGEWQIVGE 362
            +Q E+ V    FSL +  +   D G Y CHV EW+   +  W  + E
Sbjct: 773 RLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAE 820



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 72/307 (23%), Positives = 120/307 (39%), Gaps = 16/307 (5%)

Query: 63  RLTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEGAVVNV-QPTEKEFTVRLETE 121
           RL+I     ++ G++ C A  W +N + +W  +  + S    + V QP  K   +++   
Sbjct: 649 RLSISRASDTEAGKYQCVAELWRKNYNNTWTRLAERTSNLLEIRVLQPVTK---LQVSKS 705

Query: 122 KRLHMVGE--PVEFRCIPEAQNVPDRYFAVSWAFNS------SLIATMGPNAVPVLNSEF 173
           KR   + E  P++  C  ++Q   + +FAV W  +        LI     N+     +  
Sbjct: 706 KRTLTLVENKPIQLNCSVKSQTSQNSHFAVLWYVHKPSDADGKLILKTTHNSAFEYGTYA 765

Query: 174 AHREARGQLNVAKE-SDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKN 232
                R +L   +  S  +F L +      DSG Y C V E   +    +     +    
Sbjct: 766 EEEGLRARLQFERHVSGGLFSLTVQRAEVSDSGSYYCHVEEWLLSPNYAWYKLAEEVSGR 825

Query: 233 IPIIVLPLESSISVEVASNASVILEGEDLRFSCSVRMAGRPQGRFSVIWQLVDRQNR--R 290
             + V   +S + +  A     +LE   ++  C V        +  V W  V + N   R
Sbjct: 826 TEVTVKQPDSRLRLSQAQGNLSVLETRQVQLECVVLNRTSITSQLMVEW-FVWKPNHPER 884

Query: 291 SDIMWLDRDGTVQPGSSYWERSSFGSVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWV 350
             +  L RD T   G    + +  G + +E   P  + L I N   +D G Y CHV EW+
Sbjct: 885 ETVARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWL 944

Query: 351 RVVDGEW 357
               G W
Sbjct: 945 PSPSGMW 951



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 56/260 (21%), Positives = 94/260 (36%), Gaps = 40/260 (15%)

Query: 28   VISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQN 87
            V  LSRD   H G + A     G + L+      +RL I ++   D G + C   EW+ +
Sbjct: 887  VARLSRDATFHYGEQAAKNNLKGRLHLESPSPGVYRLFIQNVAVQDSGTYSCHVEEWLPS 946

Query: 88   PDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMVGEPVEFR--CIPEAQNVPDR 145
            P G WY      +    + V     + +++++T      V E   F+  C   +++  D 
Sbjct: 947  PSGMWYKRAEDTAGQTALTVM--RPDASLQVDTVVPNATVSEKAAFQLDCSIVSRSSQDS 1004

Query: 146  YFAVSWAFNSSLIATMGPNAVPVLNSEFAHREA--------------------------- 178
             FAV+W   S      G  + P L  +   RE                            
Sbjct: 1005 RFAVAW--YSLRTKAGGKRSSPGLEEQEEEREEEEEEDDDDDDDPTERTALLSVGPDAVF 1062

Query: 179  -------RGQLNVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPK 231
                    G+L   + S  ++ L +     +D+G Y+C V E   +   E+     +   
Sbjct: 1063 GPEGSPWEGRLRFQRLSPVLYRLTVLQASPQDTGNYSCHVEEWLPSPQKEWYRLTEEESA 1122

Query: 232  NIPIIVLPLESSISVEVASN 251
             I I VL    ++   + SN
Sbjct: 1123 PIGIRVLDTSPTLQSIICSN 1142



 Score = 35.8 bits (81), Expect = 0.065
 Identities = 23/89 (25%), Positives = 41/89 (46%), Gaps = 1/89 (1%)

Query: 257 EGEDLRFSCSVRMAGRPQGRFSVIWQLVDRQNRRSDIMWLDRDGTVQPGSSYWERSSFGS 316
           EG  +   C+V     P  + +  W +    +   ++  +    +  P + Y +R   G 
Sbjct: 34  EGSHITIWCNVSGYQGPSEQ-NFQWSIYLPSSPEREVQIVSTMDSSFPYAIYTQRVRGGK 92

Query: 317 VQMEQVQPNSFSLGIFNSRKEDEGQYECH 345
           + +E+VQ NS  L I + +  D G+YECH
Sbjct: 93  IFIERVQGNSTLLHITDLQARDAGEYECH 121


>gi|157694489 immunoglobulin superfamily, member 2 [Homo sapiens]
          Length = 1021

 Score =  194 bits (494), Expect = 8e-50
 Identities = 118/329 (35%), Positives = 179/329 (54%), Gaps = 7/329 (2%)

Query: 22  GEKPVEVISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEA 81
           G +  E+ISLS+DF+L  G  Y  R +  +V+L+KLG TTFRL+I  LQ SDQG+ +CEA
Sbjct: 192 GSQATEIISLSKDFILVPGPLYTERFAASDVQLNKLGPTTFRLSIERLQSSDQGQLFCEA 251

Query: 82  AEWIQNPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRCIPEAQN 141
            EWIQ+PD +W  +T+K+++   + +QP  K+F V + T   L   G+P+E  C+  +  
Sbjct: 252 TEWIQDPDETWMFITKKQTDQTTLRIQPAVKDFQVNI-TADSLFAEGKPLELVCLVVSSG 310

Query: 142 VPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLNVAKESDSVFVLKIYHLRQ 201
             D      W FN + IA +    V  L +++  R ++G+L V+K     F LKI+ L  
Sbjct: 311 -RDPQLQGIWFFNGTEIAHIDAGGVLGLKNDYKERASQGELQVSKLGPKAFSLKIFSLGP 369

Query: 202 EDSGKYNCRVTEREKTVTGEF-IDKESKHPKNIPIIVLPLESSISVEVASNASVILEGED 260
           ED G Y C V E  KT TG + + +  + P +   +  P   S+ +   +   V+ EGE 
Sbjct: 370 EDEGAYRCVVAEVMKTRTGSWQVLQRKQSPDSHVHLRKPAARSVVMSTKNKQQVVWEGET 429

Query: 261 LRFSCSVRMAGRPQGRFSVIWQLVDR-QNRRSDIMWLDRDGTVQPGSSYWERSSFGSVQM 319
           L F C    AG  +   SV W  + R Q +   +  + +DG VQ G+SY   S  G+ ++
Sbjct: 430 LAFLCK---AGGAESPLSVSWWHIPRDQTQPEFVAGMGQDGIVQLGASYGVPSYHGNTRL 486

Query: 320 EQVQPNSFSLGIFNSRKEDEGQYECHVTE 348
           E++   +F L I  +   D G YEC V+E
Sbjct: 487 EKMDWATFQLEITFTAITDSGTYECRVSE 515



 Score = 97.1 bits (240), Expect = 2e-20
 Identities = 91/357 (25%), Positives = 152/357 (42%), Gaps = 29/357 (8%)

Query: 27  EVISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQ 86
           EV  +S      S + Y  R   G+V ++++   +  L I  LQ  D GE+ C      +
Sbjct: 69  EVQIISTKDAAFSYAVYTQRVRSGDVYVERVQGNSVLLHISKLQMKDAGEYECHTPNTDE 128

Query: 87  NPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRCIPEAQNVPDRY 146
              GS+ A T        + V P     T+  +T  +    GEP+   C          +
Sbjct: 129 KYYGSYSAKTN-------LIVIPDTLSATMSSQTLGKEE--GEPLALTCEASKATAQHTH 179

Query: 147 FAVSWAFN-------SSLIATMGPNAVPVLNSEFAHREARGQLNVAKESDSVFVLKIYHL 199
            +V+W          ++ I ++  + + V    +  R A   + + K   + F L I  L
Sbjct: 180 LSVTWYLTQDGGGSQATEIISLSKDFILVPGPLYTERFAASDVQLNKLGPTTFRLSIERL 239

Query: 200 RQEDSGKYNCRVTE--REKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVASNASVILE 257
           +  D G+  C  TE  ++   T  FI K  K      + + P      V + ++ S+  E
Sbjct: 240 QSSDQGQLFCEATEWIQDPDETWMFITK--KQTDQTTLRIQPAVKDFQVNITAD-SLFAE 296

Query: 258 GEDLRFSCSVRMAGRPQGRFSVIWQLVDRQNRRSDIMWLDRDGTVQPGSSYWERSSFGSV 317
           G+ L   C V  +GR   +   IW         ++I  +D  G +   + Y ER+S G +
Sbjct: 297 GKPLELVCLVVSSGRDP-QLQGIWFF-----NGTEIAHIDAGGVLGLKNDYKERASQGEL 350

Query: 318 QMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRVVDGEWQIVGERRASTPISIIAL 374
           Q+ ++ P +FSL IF+   EDEG Y C V E ++   G WQ++  +R  +P S + L
Sbjct: 351 QVSKLGPKAFSLKIFSLGPEDEGAYRCVVAEVMKTRTGSWQVL--QRKQSPDSHVHL 405



 Score = 86.3 bits (212), Expect = 4e-17
 Identities = 54/245 (22%), Positives = 118/245 (48%), Gaps = 10/245 (4%)

Query: 17  APCKVGEKPVEVISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGE 76
           +P       ++++ + +  ++ +G E+   Q   +   +K+ +  F+L I +++ SD+G+
Sbjct: 716 SPVSTNASWLKILEMDQTNVIKTGDEFHTPQRKQKFHTEKVSQDLFQLHILNVEDSDRGK 775

Query: 77  FYCEAAEWIQNPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRCI 136
           ++C   EW+ + +G+W+ +  K+S    + ++PT  +  V              V  RC 
Sbjct: 776 YHCAVEEWLLSTNGTWHKLGEKKSGLTELKLKPTGSKVRVSKVYWTENVTEHREVAIRCS 835

Query: 137 PEAQNVPDRYFAVSWAFN-----SSLIATMGPNAVPVLNSEFAHREARGQLNVAKESDSV 191
            E+       ++V W +N     S L+  +  + +     E+     R  L+  + S + 
Sbjct: 836 LESVGSSATLYSVMWYWNRENSGSKLLVHLQHDGL----LEYGEEGLRRHLHCYRSSSTD 891

Query: 192 FVLKIYHLRQEDSGKYNCRVTERE-KTVTGEFIDKESKHPKNIPIIVLPLESSISVEVAS 250
           FVLK++ +  ED+G Y CRV E +      ++I++ S   + + + VLP E ++   + S
Sbjct: 892 FVLKLHQVEMEDAGMYWCRVAEWQLHGHPSKWINQASDESQRMVLTVLPSEPTLPSRICS 951

Query: 251 NASVI 255
           +A ++
Sbjct: 952 SAPLL 956



 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 87/357 (24%), Positives = 143/357 (40%), Gaps = 28/357 (7%)

Query: 24  KPVEVISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAE 83
           +P  V  + +D ++  G+ Y      G  RL+K+   TF+L I     +D G + C  +E
Sbjct: 456 QPEFVAGMGQDGIVQLGASYGVPSYHGNTRLEKMDWATFQLEITFTAITDSGTYECRVSE 515

Query: 84  WIQNP--DGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRCIPEAQ- 140
             +N   D SW   T+K S    V V+  E    V L + +   M+    +  C+  A  
Sbjct: 516 KSRNQARDLSW---TQKIS----VTVKSLESSLQVSLMSRQPQVMLTNTFDLSCVVRAGY 568

Query: 141 ---NVPDRYFAVSWAFN--SSLIATMGPNAVPVLNSEFAHREARGQLNVAKESDSVF--V 193
               VP     V+W F   SS I             E+ +  +R Q    K S S+F   
Sbjct: 569 SDLKVP---LTVTWQFQPASSHIFHQLIRITHNGTIEWGNFLSRFQKKT-KVSQSLFRSQ 624

Query: 194 LKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESK---HPKNIPIIVLPLESSISVEVAS 250
           L ++   +E++G Y C V   ++          +    HP  I +  LP ES + V   S
Sbjct: 625 LLVHDATEEETGVYQCEVEVYDRNSLYNNRPPRASAISHPLRIAV-TLP-ESKLKVNSRS 682

Query: 251 NASVILEGEDLRFSCSVRMAGRPQGRFSVIWQLVDRQNRRS--DIMWLDRDGTVQPGSSY 308
               +    +    CS+        + ++IW         S   I+ +D+   ++ G  +
Sbjct: 683 QVQELSINSNTDIECSILSRSNGNLQLAIIWYFSPVSTNASWLKILEMDQTNVIKTGDEF 742

Query: 309 WERSSFGSVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRVVDGEWQIVGERRA 365
                      E+V  + F L I N    D G+Y C V EW+   +G W  +GE+++
Sbjct: 743 HTPQRKQKFHTEKVSQDLFQLHILNVEDSDRGKYHCAVEEWLLSTNGTWHKLGEKKS 799



 Score = 62.0 bits (149), Expect = 8e-10
 Identities = 65/308 (21%), Positives = 120/308 (38%), Gaps = 22/308 (7%)

Query: 56  KLGRTTFR--LTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEGAV----VNVQP 109
           K+ ++ FR  L +      + G + CE   + +N   S Y     R+        + V  
Sbjct: 615 KVSQSLFRSQLLVHDATEEETGVYQCEVEVYDRN---SLYNNRPPRASAISHPLRIAVTL 671

Query: 110 TEKEFTVRLETEKRLHMVGEPVEFRCIPEAQNVPDRYFAVSWAF-----NSSLIATMGPN 164
            E +  V   ++ +   +    +  C   +++  +   A+ W F     N+S +  +  +
Sbjct: 672 PESKLKVNSRSQVQELSINSNTDIECSILSRSNGNLQLAIIWYFSPVSTNASWLKILEMD 731

Query: 165 AVPVLNS--EFAHREARGQLNVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEF 222
              V+ +  EF   + + + +  K S  +F L I ++   D GKY+C V E   +  G +
Sbjct: 732 QTNVIKTGDEFHTPQRKQKFHTEKVSQDLFQLHILNVEDSDRGKYHCAVEEWLLSTNGTW 791

Query: 223 IDKESKHPKNIPIIVLPLESSISVEVASNASVILEGEDLRFSCSVRMAGRPQGRFSVIWQ 282
                K      + + P  S + V        + E  ++   CS+   G     +SV+W 
Sbjct: 792 HKLGEKKSGLTELKLKPTGSKVRVSKVYWTENVTEHREVAIRCSLESVGSSATLYSVMWY 851

Query: 283 LVDRQNRRSDIM-WLDRDGTVQPGSSYWERSSFGSVQMEQVQPNSFSLGIFNSRKEDEGQ 341
             +R+N  S ++  L  DG ++    Y E      +   +     F L +     ED G 
Sbjct: 852 W-NRENSGSKLLVHLQHDGLLE----YGEEGLRRHLHCYRSSSTDFVLKLHQVEMEDAGM 906

Query: 342 YECHVTEW 349
           Y C V EW
Sbjct: 907 YWCRVAEW 914


>gi|16445029 immunoglobulin superfamily, member 8 [Homo sapiens]
          Length = 613

 Score =  124 bits (310), Expect = 2e-28
 Identities = 97/360 (26%), Positives = 158/360 (43%), Gaps = 22/360 (6%)

Query: 27  EVISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQ 86
           EV+ +  D  + +G+ YA R + GE+RL K G   +R+ +   Q  D G ++C AAEWIQ
Sbjct: 218 EVVGIRSDLAVEAGAPYAERLAAGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEWIQ 277

Query: 87  NPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRC-IPEAQNVPDR 145
           +PDGSW  +  KR+  A V+VQ    +  V +   +R    GEP+E  C +  A     R
Sbjct: 278 DPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALPPAGR 337

Query: 146 YFAVSWAFNSSLIATMGP-NAVPVLNSEFAHREARG----QLNVAKESDSVFVLKIYHLR 200
           + A S  +  +     GP   V  L++E       G     + + K +   + L++   R
Sbjct: 338 HAAYSVGWEMAPAGAPGPGRLVAQLDTEGVGSLGPGYEGRHIAMEKVASRTYRLRLEAAR 397

Query: 201 QEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVAS--NASVILEG 258
             D+G Y C      +       +  S   + +P+ V   E  + +E  +      +  G
Sbjct: 398 PGDAGTYRCLAKAYVRGSGTRLREAASARSRPLPVHV--REEGVVLEAVAWLAGGTVYRG 455

Query: 259 EDLRFSCSVRMAGRPQG-RFSVIWQLVDRQNRRSD------IMWLDRDGTVQPGSSYWER 311
           E     C++ + G P G R +  W +   ++          +  + +DG  + G     R
Sbjct: 456 ETASLLCNISVRGGPPGLRLAASWWVERPEDGELSSVPAQLVGGVGQDGVAELG----VR 511

Query: 312 SSFGSVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRVVDGEWQIVGERRASTPISI 371
              G V +E V P S  L + +   EDEG Y C  + WV+  D  W   G  R S P+++
Sbjct: 512 PGGGPVSVELVGPRSHRLRLHSLGPEDEGVYHCAPSAWVQHADYSWYQAGSAR-SGPVTV 570



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 44/208 (21%), Positives = 87/208 (41%), Gaps = 22/208 (10%)

Query: 173 FAHREARGQLNVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKN 232
           F  R   G++ V +      VLKI  L+ +D+G Y C     +    G +  K       
Sbjct: 91  FKSRVVAGEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLGSYSGK------- 143

Query: 233 IPIIVLPLESSIS----------VEVASNASVILEGEDLRFSCSVRMAGRPQGRFSV--- 279
           + + VLP    +S             +     + EG++L   C  R + +     +V   
Sbjct: 144 VELRVLPDVLQVSAAPPGPRGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLAVSFG 203

Query: 280 --IWQLVDRQNRRSDIMWLDRDGTVQPGSSYWERSSFGSVQMEQVQPNSFSLGIFNSRKE 337
             + +    ++   +++ +  D  V+ G+ Y ER + G +++ +   + + + +  ++  
Sbjct: 204 RSVPEAPVGRSTLQEVVGIRSDLAVEAGAPYAERLAAGELRLGKEGTDRYRMVVGGAQAG 263

Query: 338 DEGQYECHVTEWVRVVDGEWQIVGERRA 365
           D G Y C   EW++  DG W  + E+RA
Sbjct: 264 DAGTYHCTAAEWIQDPDGSWAQIAEKRA 291



 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 74/320 (23%), Positives = 119/320 (37%), Gaps = 22/320 (6%)

Query: 50  GEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEGAVVNVQ- 108
           GEV++ +L      L I  LQ  D G + C          GS+      R    V+ V  
Sbjct: 98  GEVQVQRLQGDAVVLKIARLQAQDAGIYECHTPSTDTRYLGSYSGKVELRVLPDVLQVSA 157

Query: 109 --PTEKEFTVRLETEKRLHMVGEPVEFRCIPEAQNVPDRYFAVSWAFN--------SSLI 158
             P  +         +     G+ +   C+         + AVS+  +        S+L 
Sbjct: 158 APPGPRGRQAPTSPPRMTVHEGQELALGCLARTSTQKHTHLAVSFGRSVPEAPVGRSTLQ 217

Query: 159 ATMG--PNAVPVLNSEFAHREARGQLNVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREK 216
             +G   +      + +A R A G+L + KE    + + +   +  D+G Y+C   E  +
Sbjct: 218 EVVGIRSDLAVEAGAPYAERLAAGELRLGKEGTDRYRMVVGGAQAGDAGTYHCTAAEWIQ 277

Query: 217 TVTGEFIDKESKHPKNIPIIVLPLESSISVEVASNASVILEGEDLRFSCSVRMAGRPQGR 276
              G +     K      + V  L S ++V V      I  GE L   C+V  A  P GR
Sbjct: 278 DPDGSWAQIAEKRAVLAHVDVQTLSSQLAVTVGPGERRIGPGEPLELLCNVSGALPPAGR 337

Query: 277 ---FSVIWQL--VDRQNRRSDIMWLDRDGTVQPGSSYWERSSFGSVQMEQVQPNSFSLGI 331
              +SV W++           +  LD +G    G  Y  R     + ME+V   ++ L +
Sbjct: 338 HAAYSVGWEMAPAGAPGPGRLVAQLDTEGVGSLGPGYEGR----HIAMEKVASRTYRLRL 393

Query: 332 FNSRKEDEGQYECHVTEWVR 351
             +R  D G Y C    +VR
Sbjct: 394 EAARPGDAGTYRCLAKAYVR 413


>gi|41152506 prostaglandin F2 receptor negative regulator [Homo
           sapiens]
          Length = 879

 Score = 93.2 bits (230), Expect = 3e-19
 Identities = 79/354 (22%), Positives = 150/354 (42%), Gaps = 18/354 (5%)

Query: 28  VISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQN 87
           V++L+ +   H G  Y  R   G+VRLD +G   +RL++     +DQG + C  +EWI  
Sbjct: 196 VLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAE 255

Query: 88  PDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMV-GEPVEFRCIPEAQNVPDRY 146
             G+W  +  K  E A V +QP+     +R    K + +  G+ ++  C        D  
Sbjct: 256 -QGNWQEIQEKAVEVATVVIQPS----VLRAAVPKNVSVAEGKELDLTCNITTDRADDVR 310

Query: 147 FAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLNVAKESDSVFVLKIYHLRQEDSGK 206
             V+W+F+    +T+  + V       +   +   + ++      + L +  + +E+SG 
Sbjct: 311 PEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSSPHVALSHVDARSYHLLVRDVSKENSGY 370

Query: 207 YNCRVT--EREKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVASNASVILEGEDLRFS 264
           Y C V+        +   + +    P  + +  L  +  + +  +       +  +L   
Sbjct: 371 YYCHVSLWAPGHNRSWHKVAEAVSSPAGVGVTWLEPDYQVYLNASKVPGFADDPTELACR 430

Query: 265 CSVRMAGRPQGRFSVIWQLVDRQNRRSD-------IMWLDRDGTVQPGSSYWERSSFGSV 317
                +G    RF+V W    R NRRSD       +  +D D T++ G    +R+  G  
Sbjct: 431 VVDTKSGEANVRFTVSWYY--RMNRRSDNVVTSELLAVMDGDWTLKYGERSKQRAQDGDF 488

Query: 318 QMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRVVDGEWQIVGERRASTPISI 371
              +   ++F+  I  + +ED G Y C V+ W +  +  W +  +   S P++I
Sbjct: 489 IFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTKQRNNSW-VKSKDVFSKPVNI 541



 Score = 92.0 bits (227), Expect = 8e-19
 Identities = 81/358 (22%), Positives = 132/358 (36%), Gaps = 33/358 (9%)

Query: 31  LSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQNPDG 90
           L RD ++HS    A         L  +   ++ L +  +   + G +YC  + W    + 
Sbjct: 334 LDRDSLVHSSPHVA---------LSHVDARSYHLLVRDVSKENSGYYYCHVSLWAPGHNR 384

Query: 91  SWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRC--IPEAQNVPDRYFA 148
           SW+ +    S  A V V   E ++ V L   K      +P E  C  +       +  F 
Sbjct: 385 SWHKVAEAVSSPAGVGVTWLEPDYQVYLNASKVPGFADDPTELACRVVDTKSGEANVRFT 444

Query: 149 VSWAFN----------SSLIATMGPNAVPVLNSEFAHREARGQLNVAKESDSVFVLKIYH 198
           VSW +           S L+A M  +           R   G    +KE    F  +I  
Sbjct: 445 VSWYYRMNRRSDNVVTSELLAVMDGDWTLKYGERSKQRAQDGDFIFSKEHTDTFNFRIQR 504

Query: 199 LRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVASNASVILEG 258
             +ED G Y C V+   K     ++  +    K + I     +S + V+          G
Sbjct: 505 TTEEDRGNYYCVVSAWTKQRNNSWVKSKDVFSKPVNIFWALEDSVLVVKARQPKPFFAAG 564

Query: 259 EDLRFSCSVRMAGRPQGRFSVIWQL------VDRQNRRSDIMWLDRDGTVQPGSSYWERS 312
                +C V        R+SV+         +   N    I+ LD+D  V+   ++ + S
Sbjct: 565 NTFEMTCKVSSKNIKSPRYSVLIMAEKPVGDLSSPNETKYIISLDQDSVVKL-ENWTDAS 623

Query: 313 SFGSVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRVVDGEWQIVGERRASTPIS 370
               V +E+VQ + F   ++ ++  D G Y C VT W  V    W     R A+T +S
Sbjct: 624 RVDGVVLEKVQEDEFRYRMYQTQVSDAGLYRCMVTAWSPVRGSLW-----REAATSLS 676



 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 60/261 (22%), Positives = 107/261 (40%), Gaps = 14/261 (5%)

Query: 116 VRLETEKRLHMVGEPVEFRCIPEAQNVPDRYFAVSWAFNS---SLIATMGPNAVPVLNSE 172
           VR+ T   + +VG  +   C     + P       W+F+S   S +       V      
Sbjct: 24  VRVPTATLVRVVGTELVIPCNVSDYDGPSEQ-NFDWSFSSLGSSFVELASTWEVGFPAQL 82

Query: 173 FAHREARGQLNVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKN 232
           +  R  RG++ + + ++    L I +++  D G Y C     + TV G + D        
Sbjct: 83  YQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYED-------T 135

Query: 233 IPIIVLPLESSISVEVASNASVIL-EGEDLRFSCSVRMAGRPQGRFSVIWQLVDRQNRRS 291
           + + VL     +        S+ L EGE     C+   A       +++W+ V R   R 
Sbjct: 136 VQVKVLADSLHVGPSARPPPSLSLREGEPFELRCTAASASPLHTHLALLWE-VHRGPARR 194

Query: 292 DIMWLDRDGTVQPGSSYWERSSFGSVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVR 351
            ++ L  +G   PG  Y +R   G V+++ V  +++ L +  +   D+G Y C V+EW+ 
Sbjct: 195 SVLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWI- 253

Query: 352 VVDGEWQIVGERRASTPISII 372
              G WQ + E+       +I
Sbjct: 254 AEQGNWQEIQEKAVEVATVVI 274



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 81/334 (24%), Positives = 128/334 (38%), Gaps = 31/334 (9%)

Query: 43  YAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEG 102
           Y  R   GE+ L +       L I ++QPSDQG + C          G++    + +   
Sbjct: 83  YQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLA 142

Query: 103 AVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRCIPEAQNVPDRYFAVSW------AFNSS 156
             ++V P+ +        E      GEP E RC   + +    + A+ W      A  S 
Sbjct: 143 DSLHVGPSARPPPSLSLRE------GEPFELRCTAASASPLHTHLALLWEVHRGPARRSV 196

Query: 157 LIATMGPNAVPVLNSEFAHREARGQLNVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREK 216
           L  T      P L  E   R   G + +       + L +      D G Y C V+E   
Sbjct: 197 LALTHEGRFHPGLGYE--QRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSE-WI 253

Query: 217 TVTGEFIDKESKHPKNIPIIVLPLESSISVEVASNASVILEGEDLRFSCSVRMAGRPQGR 276
              G + + + K  +   +++ P  S +   V  N SV  EG++L  +C++        R
Sbjct: 254 AEQGNWQEIQEKAVEVATVVIQP--SVLRAAVPKNVSV-AEGKELDLTCNITTDRADDVR 310

Query: 277 FSVIW---QLVDRQNRRSDIM-WLDRDGTVQPGSSYWERSSFGSVQMEQVQPNSFSLGIF 332
             V W   ++ D     S ++  LDRD  V          S   V +  V   S+ L + 
Sbjct: 311 PEVTWSFSRMPDSTLPGSRVLARLDRDSLVH---------SSPHVALSHVDARSYHLLVR 361

Query: 333 NSRKEDEGQYECHVTEWVRVVDGEWQIVGERRAS 366
           +  KE+ G Y CHV+ W    +  W  V E  +S
Sbjct: 362 DVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSS 395



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 71/343 (20%), Positives = 120/343 (34%), Gaps = 23/343 (6%)

Query: 34  DFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQNPDGSWY 93
           D+ L  G     R   G+    K    TF   I      D+G +YC  + W +  + SW 
Sbjct: 470 DWTLKYGERSKQRAQDGDFIFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTKQRNNSWV 529

Query: 94  AMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRCIPEAQNVPDRYFAV---- 149
                 S+   +     +    V+    K     G   E  C   ++N+    ++V    
Sbjct: 530 KSKDVFSKPVNIFWALEDSVLVVKARQPKPFFAAGNTFEMTCKVSSKNIKSPRYSVLIMA 589

Query: 150 -------SWAFNSSLIATMGPNAVPVLNSEFAHREARGQLNVAKESDSVFVLKIYHLRQE 202
                  S    +  I ++  ++V  L +        G + + K  +  F  ++Y  +  
Sbjct: 590 EKPVGDLSSPNETKYIISLDQDSVVKLENWTDASRVDGVV-LEKVQEDEFRYRMYQTQVS 648

Query: 203 DSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVASNASVILEGEDLR 262
           D+G Y C VT         + +  +     I I         +  V S+   ++ G+ ++
Sbjct: 649 DAGLYRCMVTAWSPVRGSLWREAATSLSNPIEIDFQTSGPIFNASVHSDTPSVIRGDLIK 708

Query: 263 FSCSVRMAGRPQG----RFSVIWQLVDRQNRRSD---IMWLDRDGTVQPGSSYWERSSFG 315
             C + + G         F V W  V           +  LDR G V      W+     
Sbjct: 709 LFCIITVEGAALDPDDMAFDVSWFAVHSFGLDKAPVLLSSLDRKGIVTTSRRDWK----S 764

Query: 316 SVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRVVDGEWQ 358
            + +E+V    F L +  S  +D G Y C VT WV+   G WQ
Sbjct: 765 DLSLERVSVLEFLLQVHGSEDQDFGNYYCSVTPWVKSPTGSWQ 807



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 52/237 (21%), Positives = 94/237 (39%), Gaps = 17/237 (7%)

Query: 13  EGPLAPCKVGEKPVEVISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPS 72
           E P+       +   +ISL +D ++     +     +  V L+K+    FR  ++  Q S
Sbjct: 590 EKPVGDLSSPNETKYIISLDQDSVVKL-ENWTDASRVDGVVLEKVQEDEFRYRMYQTQVS 648

Query: 73  DQGEFYCEAAEWIQNPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMVGEPVE 132
           D G + C    W       W       S    ++ Q +   F   + ++    + G+ ++
Sbjct: 649 DAGLYRCMVTAWSPVRGSLWREAATSLSNPIEIDFQTSGPIFNASVHSDTPSVIRGDLIK 708

Query: 133 FRCIPEAQNVP----DRYFAVSWAFNSSLIATMGPNAVPVLNSEF--------AHREARG 180
             CI   +       D  F VSW      + + G +  PVL S          + R+ + 
Sbjct: 709 LFCIITVEGAALDPDDMAFDVSWF----AVHSFGLDKAPVLLSSLDRKGIVTTSRRDWKS 764

Query: 181 QLNVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIV 237
            L++ + S   F+L+++    +D G Y C VT   K+ TG +  +   H K + I V
Sbjct: 765 DLSLERVSVLEFLLQVHGSEDQDFGNYYCSVTPWVKSPTGSWQKEAEIHSKPVFITV 821



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 25  PVEVISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEW 84
           PV + SL R  ++ + S   W+  L    L+++    F L +   +  D G +YC    W
Sbjct: 743 PVLLSSLDRKGIVTT-SRRDWKSDLS---LERVSVLEFLLQVHGSEDQDFGNYYCSVTPW 798

Query: 85  IQNPDGSWYAMTRKRSEGAVVNVQ 108
           +++P GSW       S+   + V+
Sbjct: 799 VKSPTGSWQKEAEIHSKPVFITVK 822


>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
          Length = 4391

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 63/284 (22%), Positives = 113/284 (39%), Gaps = 53/284 (18%)

Query: 5    VLVQTLYIEGPLAPCKVGEKPVEV-----ISLSRDFMLHSGSEYAWRQSLGEVRLDKLGR 59
            V ++   I GP+ P ++      V     + LS      + ++  W +  G +      R
Sbjct: 2233 VTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVR 2292

Query: 60   TTFRLTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLE 119
             + RL IF   P+D G++ C A+  ++    +   +T   ++GA +   P      +R+E
Sbjct: 2293 GS-RLYIFQASPADAGQYVCRASNGME----ASITVTVTGTQGANL-AYPAGSTQPIRIE 2346

Query: 120  TEKRLHMVGEPVEFRCIPEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREAR 179
                    G+ ++  C+   Q+    +  V+W                       H+   
Sbjct: 2347 PSSSQVAEGQTLDLNCVVPGQS----HAQVTW-----------------------HKRG- 2378

Query: 180  GQLNVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKNI-PIIVL 238
            G L V  ++    +L++Y     DSG+Y CR       V G  +  E+     I P   +
Sbjct: 2379 GSLPVRHQTHG-SLLRLYQASPADSGEYVCR-------VLGSSVPLEASVLVTIEPAGSV 2430

Query: 239  P-LESSISVEVASNASVILEGEDLRFSCSVRMAGRPQGRFSVIW 281
            P L  + +V + S++S + EG+ L  +C V  AG  Q    V W
Sbjct: 2431 PALGVTPTVRIESSSSQVAEGQTLDLNCLV--AG--QAHAQVTW 2470



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 43/208 (20%), Positives = 80/208 (38%), Gaps = 39/208 (18%)

Query: 63   RLTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEK 122
            RL + H+ P+D GE+ C        P  +   +T + S  + V+V        +R+E   
Sbjct: 2777 RLRLHHVSPADSGEYVCRVM-GSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSS 2835

Query: 123  RLHMVGEPVEFRCIPEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQL 182
                 G+ ++ +C+   Q     +  V+W      +               A  +  G L
Sbjct: 2836 SRVAEGQTLDLKCVVPGQ----AHAQVTWHKRGGNLP--------------ARHQVHGPL 2877

Query: 183  NVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEF---IDKESKHPKNIPIIVLP 239
                       L++  +   DSG+Y+C+VT    T+       I+  S  P   P +  P
Sbjct: 2878 -----------LRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQP 2926

Query: 240  LESSISVEVASNASVILEGEDLRFSCSV 267
                  + + +++S + EG+ L  +C V
Sbjct: 2927 ------IYIEASSSHVTEGQTLDLNCVV 2948



 Score = 36.6 bits (83), Expect = 0.038
 Identities = 41/207 (19%), Positives = 75/207 (36%), Gaps = 42/207 (20%)

Query: 63   RLTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEK 122
            RL I  + P+D GE+ C  +    + + S     +      V +V P      +R+E+  
Sbjct: 2584 RLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSP-----PIRIESSS 2638

Query: 123  RLHMVGEPVEFRCIPEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQL 182
               + G+ ++  C+   Q                      P A+           +R Q 
Sbjct: 2639 PTVVEGQTLDLNCVVARQ----------------------PQAIITWYKRGGSLPSRHQT 2676

Query: 183  NVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVLPLE- 241
            + +        L+++ +   DSG+Y CR       +    +   S      P    P   
Sbjct: 2677 HGSH-------LRLHQMSVADSGEYVCRANNNIDALEASIVISVS------PSAGSPSAP 2723

Query: 242  -SSISVEVASNASVILEGEDLRFSCSV 267
             SS+ + + S++S + EGE L  +C V
Sbjct: 2724 GSSMPIRIESSSSHVAEGETLDLNCVV 2750



 Score = 35.8 bits (81), Expect = 0.065
 Identities = 25/106 (23%), Positives = 40/106 (37%), Gaps = 18/106 (16%)

Query: 202  EDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVASNASVILEGEDL 261
            EDSG+Y CRVT +  +            P ++P   +P  S+ +V+V         G  +
Sbjct: 3358 EDSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASV 3417

Query: 262  RFSCSVRMAGRPQGRFSVIWQLVDRQNRRSDIMWLDRDGTVQPGSS 307
             F C+V                    +R + + W    G + PG S
Sbjct: 3418 EFHCAV------------------PSDRGTQLRWFKEGGQLPPGHS 3445



 Score = 32.0 bits (71), Expect = 0.93
 Identities = 44/220 (20%), Positives = 75/220 (34%), Gaps = 66/220 (30%)

Query: 64   LTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEGAVVNVQPTE-------KEFTV 116
            L +  +  +D GE+ C A   I   + S            V++V P+            +
Sbjct: 2681 LRLHQMSVADSGEYVCRANNNIDALEAS-----------IVISVSPSAGSPSAPGSSMPI 2729

Query: 117  RLETEKRLHMVGEPVEFRCIPEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHR 176
            R+E+       GE ++  C+   Q     +  V+W      + +              H 
Sbjct: 2730 RIESSSSHVAEGETLDLNCVVPGQ----AHAQVTWHKRGGSLPS--------------HH 2771

Query: 177  EARGQLNVAKESDSVFVLKIYHLRQEDSGKYNCRV------TEREKTVTGEFIDKESKH- 229
            + RG             L+++H+   DSG+Y CRV       E    VT E     + H 
Sbjct: 2772 QTRGSR-----------LRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHV 2820

Query: 230  --PKNIPIIVLPLESSISVEVASNASVILEGEDLRFSCSV 267
              P   P           + +  ++S + EG+ L   C V
Sbjct: 2821 PAPGGAP----------PIRIEPSSSRVAEGQTLDLKCVV 2850



 Score = 30.4 bits (67), Expect = 2.7
 Identities = 34/158 (21%), Positives = 59/158 (37%), Gaps = 44/158 (27%)

Query: 194  LKIYHLRQEDSGKYNCRVTE----REKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVA 249
            L++  +   DSG+Y CRV      +E ++T   +      P   P+      S+  + + 
Sbjct: 2102 LRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPV----PGSTRPIRIE 2157

Query: 250  SNASVILEGEDLRFSCSVRMAGRPQGRFSVIWQLVDRQNRRSDIMWLDRDGTVQPGSSYW 309
             ++S + EG+ L  +C V      Q                  + W  R G++       
Sbjct: 2158 PSSSHVAEGQTLDLNCVVPGQAHAQ------------------VTWHKRGGSLPA----- 2194

Query: 310  ERSSFGS-VQMEQVQPNSFSLGIFNSRKEDEGQYECHV 346
               + GS +++ QV P             D G+Y CHV
Sbjct: 2195 RHQTHGSLLRLHQVTP------------ADSGEYVCHV 2220



 Score = 30.0 bits (66), Expect = 3.5
 Identities = 52/287 (18%), Positives = 89/287 (31%), Gaps = 75/287 (26%)

Query: 63   RLTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEK 122
            RL +  + P+D GE+ C         + S        +               +R+E   
Sbjct: 2101 RLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSS 2160

Query: 123  RLHMVGEPVEFRCIPEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQL 182
                 G+ ++  C+   Q     +  V+W                           RG  
Sbjct: 2161 SHVAEGQTLDLNCVVPGQ----AHAQVTW-------------------------HKRGGS 2191

Query: 183  NVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFI--DKESKHPKNIPIIVLPL 240
              A+      +L+++ +   DSG+Y C V      +    +   + S  P  IP      
Sbjct: 2192 LPARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIP------ 2245

Query: 241  ESSISVEVASNASVILEGEDLRFSCSVRMAGRPQGRFSVIWQLVDRQNRRSDIMWLDRDG 300
                 V + S++S + EG+ L  SC V  AG+                  + + W  R G
Sbjct: 2246 ----PVRIESSSSTVAEGQTLDLSCVV--AGQ----------------AHAQVTWYKRGG 2283

Query: 301  TVQPGSSYWERSSFGSVQMEQVQPNSFSLGIFNSRKEDEGQYECHVT 347
            ++                  + Q     L IF +   D GQY C  +
Sbjct: 2284 SLP----------------ARHQVRGSRLYIFQASPADAGQYVCRAS 2314


>gi|31377806 polymeric immunoglobulin receptor precursor [Homo
           sapiens]
          Length = 764

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 77/356 (21%), Positives = 135/356 (37%), Gaps = 81/356 (22%)

Query: 20  KVGEKPVEVISLSRDFMLHSGSEYAWRQSLGEVRLD--KLGRTTFRLTIFHLQPSDQGEF 77
           ++G  PV VI           S Y      G +RLD    G+  F + I  L+ SD G++
Sbjct: 168 QIGLYPVLVID---------SSGYVNPNYTGRIRLDIQGTGQLLFSVVINQLRLSDAGQY 218

Query: 78  YCEAAEWIQNPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRCI- 136
            C+A +   +         +K ++  V+  +P           E     +   V F C  
Sbjct: 219 LCQAGDDSNS--------NKKNADLQVLKPEP-----------ELVYEDLRGSVTFHCAL 259

Query: 137 -PEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLNVAKESDSVFVLK 195
            PE  NV       S   N  ++        P         E R  LN  ++ D  F + 
Sbjct: 260 GPEVANVAKFLCRQSSGENCDVVVNTLGKRAPAF-------EGRILLN-PQDKDGSFSVV 311

Query: 196 IYHLRQEDSGKYNCRVTEREKTVTGE-------FIDKESKHPKNIPIIVLPLESSISVEV 248
           I  LR+ED+G+Y C      +   G        F+++ES  P++  ++      S++V  
Sbjct: 312 ITGLRKEDAGRYLCGAHSDGQLQEGSPIQAWQLFVNEESTIPRSPTVVKGVAGGSVAVLC 371

Query: 249 ASNASVILEGEDLRFSCSVRMAGRPQGRFSVIWQLVDRQNRRSDIMWLDRDGTVQPGSSY 308
             N     E + +++ C              +W+    QN R  ++ +D +G V+  + Y
Sbjct: 372 PYNRK---ESKSIKYWC--------------LWE--GAQNGRCPLL-VDSEGWVK--AQY 409

Query: 309 WERSSFGSVQMEQVQPNSFSLGIFNSRKEDEGQYEC--------HVTEWVRVVDGE 356
             R S     +E+    +F++ +      D G Y C          T  +++++GE
Sbjct: 410 EGRLSL----LEEPGNGTFTVILNQLTSRDAGFYWCLTNGDTLWRTTVEIKIIEGE 461


>gi|33519481 neural cell adhesion molecule 2 precursor [Homo
           sapiens]
          Length = 837

 Score = 39.3 bits (90), Expect = 0.006
 Identities = 47/216 (21%), Positives = 85/216 (39%), Gaps = 49/216 (22%)

Query: 63  RLTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEK 122
           RLTI++    D G + C+A +             + +++ A V ++  +K  T R     
Sbjct: 77  RLTIYNANIEDAGIYRCQATD------------AKGQTQEATVVLEIYQK-LTFREVVSP 123

Query: 123 RLHMVGEPVEFRCIPEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQL 182
           +    GE  E  C   +   P    AVSW +++  + T+  N   +L +           
Sbjct: 124 QEFKQGEDAEVVCRVSSSPAP----AVSWLYHNEEVTTISDNRFAMLANN---------- 169

Query: 183 NVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVLPLES 242
                      L+I ++ + D G Y C   E      GE   ++        I+++ +  
Sbjct: 170 ----------NLQILNINKSDEGIYRC---EGRVEARGEIDFRDI-------IVIVNVPP 209

Query: 243 SISVEVASNASVILEGEDLRFSCSVRMAGRPQGRFS 278
           +IS+   S  +    GE++ FSC  R +G P+   S
Sbjct: 210 AISMPQKSFNATAERGEEMTFSC--RASGSPEPAIS 243


>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 5065

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 62/281 (22%), Positives = 102/281 (36%), Gaps = 63/281 (22%)

Query: 64   LTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKR 123
            L +  + P+D G++ C+A     N  GS    T +R++  VV V P+ +E   +      
Sbjct: 1263 LFLASVSPADSGDYECQAT----NEVGS----TSRRAK-LVVYVPPSIREDGRKANVSG- 1312

Query: 124  LHMVGEPVEFRCIPEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLN 183
              M G+ +   C      VP+    + W  ++ L+       VP+  + +      GQ+ 
Sbjct: 1313 --MAGQSLTLECDANGFPVPE----IVWLKDAQLVG------VPLGWAGYGWDLGWGQVG 1360

Query: 184  VAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVLPLESS 243
              +  D    L    +++ DSG Y+CR   +  T   +F            ++VL   S 
Sbjct: 1361 GHRLLDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQRDF-----------HLLVLTPPSV 1409

Query: 244  ISVEVASNASVILEGEDLRFSCSVRMAGRPQGRFSVIWQLVDRQNRRSDIMWLDRDGTVQ 303
            +    A    + L G D+   C       PQ                  + W      V 
Sbjct: 1410 LGAGAAQEV-LGLAGADVELQCWTSGVPTPQ------------------VEWTKDRQPVL 1450

Query: 304  PGSSYWERSSFGSVQMEQVQPNSFSLGIFNSRKEDEGQYEC 344
            PG  +            QVQ +   L I  S   DEG+Y+C
Sbjct: 1451 PGGPHL-----------QVQEDGQVLRITGSHVGDEGRYQC 1480



 Score = 32.7 bits (73), Expect = 0.55
 Identities = 49/220 (22%), Positives = 86/220 (39%), Gaps = 41/220 (18%)

Query: 108  QPTEKEFTVRLETE-KRLHM----VGEPVEFRCIPE-AQNVPDRYFAVSWAFNSSLIATM 161
            QP   E  ++L+ + + LH+          + C+ E      +R F +S      LI  +
Sbjct: 2297 QPVGAELGLQLQNQGQSLHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDL 2356

Query: 162  GP--NAVPVLNSEF------------AHREARGQLNVAKESDSV-----FVLKIYHLRQE 202
             P  N    L+S              A R  RG+  V+   D+      ++LK+   +++
Sbjct: 2357 DPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLLAGGWMLKMTQTQEQ 2416

Query: 203  DSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVASNASVILEGEDLR 262
            DSG Y+C  +             E++   ++ ++V P   SI  E       +L+G+   
Sbjct: 2417 DSGLYSCLASNEA---------GEARRNFSVEVLVPP---SIENEDLEEVIKVLDGQTAH 2464

Query: 263  FSCSVRMAGRPQGRFSVIWQLVDRQNRRSDIMWLDRDGTV 302
              C+V   G PQ + +  W    R   R D   +  DG +
Sbjct: 2465 LMCNV--TGHPQPKLT--WFKDGRPLARGDAHHISPDGVL 2500



 Score = 32.3 bits (72), Expect = 0.71
 Identities = 14/27 (51%), Positives = 18/27 (66%)

Query: 321  QVQPNSFSLGIFNSRKEDEGQYECHVT 347
            Q+ P +  L I N++KED GQY C VT
Sbjct: 2589 QLLPGTHGLQILNAQKEDAGQYTCVVT 2615



 Score = 30.4 bits (67), Expect = 2.7
 Identities = 27/139 (19%), Positives = 51/139 (36%), Gaps = 40/139 (28%)

Query: 127  VGEPVEFRCIPEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLNVAK 186
            VG  ++  C+     VPD    + W            + +P+  S   H+   G L    
Sbjct: 4232 VGGSIQLDCVVRGDPVPD----IHWI----------KDGLPLRGSHLRHQLQNGSLT--- 4274

Query: 187  ESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVLPLESSISV 246
                     I+   ++D+G+Y C + E E  V  +             +++L L+S+   
Sbjct: 4275 ---------IHRTERDDAGRYQC-LAENEMGVAKK-------------VVILVLQSAPVF 4311

Query: 247  EVASNASVILEGEDLRFSC 265
            +V      +  G+D+   C
Sbjct: 4312 QVEPQDMTVRSGDDVALRC 4330


>gi|51988914 fibroblast growth factor receptor-like 1 precursor
           [Homo sapiens]
          Length = 504

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 37/155 (23%), Positives = 59/155 (38%), Gaps = 22/155 (14%)

Query: 192 FVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVASN 251
           + L + +LR EDSGKY CRV+ R   +   +     +  ++ P++      + +V+    
Sbjct: 204 WTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQRTRSKPVLTGTHPVNTTVDFGGT 263

Query: 252 ASVILEGEDLRFSCSVRMAGRP--QGRFSVIWQLVDRQNRRSDIMWLDRDGTVQPGSSYW 309
            S         F C VR   +P  Q    V +    R N   D+    +   V P    W
Sbjct: 264 TS---------FQCKVRSDVKPVIQWLKRVEYGAEGRHNSTIDVG--GQKFVVLPTGDVW 312

Query: 310 ERSSFGSVQMEQVQPNSFSLGIFNSRKEDEGQYEC 344
            R     +           L I  +R++D G Y C
Sbjct: 313 SRPDGSYLN---------KLLITRARQDDAGMYIC 338



 Score = 33.9 bits (76), Expect = 0.25
 Identities = 41/188 (21%), Positives = 77/188 (40%), Gaps = 36/188 (19%)

Query: 194 LKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVL----PLESSISVEVA 249
           LK+  + +ED+G Y C+ T    +++            N  ++VL    P + S+  + +
Sbjct: 84  LKVKQVEREDAGVYVCKATNGFGSLS-----------VNYTLVVLDDISPGKESLGPDSS 132

Query: 250 SNASVILEGEDL---RFS----CSVRMAGRPQGRFSVIWQLVDRQNRRSDIMWLDRDGTV 302
           S        +     RF+       R+  RP G  SV  + V   + R DI W+  D   
Sbjct: 133 SGGQEDPASQQWARPRFTQPSKMRRRVIARPVGS-SVRLKCVASGHPRPDITWMKDD--- 188

Query: 303 QPGSSYWERSSFGSVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRVVDGEWQI-VG 361
                     +    +  + +   ++L + N R ED G+Y C V+     ++  +++ V 
Sbjct: 189 ---------QALTRPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVI 239

Query: 362 ERRASTPI 369
           +R  S P+
Sbjct: 240 QRTRSKPV 247


>gi|51988910 fibroblast growth factor receptor-like 1 precursor
           [Homo sapiens]
          Length = 504

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 37/155 (23%), Positives = 59/155 (38%), Gaps = 22/155 (14%)

Query: 192 FVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVASN 251
           + L + +LR EDSGKY CRV+ R   +   +     +  ++ P++      + +V+    
Sbjct: 204 WTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQRTRSKPVLTGTHPVNTTVDFGGT 263

Query: 252 ASVILEGEDLRFSCSVRMAGRP--QGRFSVIWQLVDRQNRRSDIMWLDRDGTVQPGSSYW 309
            S         F C VR   +P  Q    V +    R N   D+    +   V P    W
Sbjct: 264 TS---------FQCKVRSDVKPVIQWLKRVEYGAEGRHNSTIDVG--GQKFVVLPTGDVW 312

Query: 310 ERSSFGSVQMEQVQPNSFSLGIFNSRKEDEGQYEC 344
            R     +           L I  +R++D G Y C
Sbjct: 313 SRPDGSYLN---------KLLITRARQDDAGMYIC 338



 Score = 33.9 bits (76), Expect = 0.25
 Identities = 41/188 (21%), Positives = 77/188 (40%), Gaps = 36/188 (19%)

Query: 194 LKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVL----PLESSISVEVA 249
           LK+  + +ED+G Y C+ T    +++            N  ++VL    P + S+  + +
Sbjct: 84  LKVKQVEREDAGVYVCKATNGFGSLS-----------VNYTLVVLDDISPGKESLGPDSS 132

Query: 250 SNASVILEGEDL---RFS----CSVRMAGRPQGRFSVIWQLVDRQNRRSDIMWLDRDGTV 302
           S        +     RF+       R+  RP G  SV  + V   + R DI W+  D   
Sbjct: 133 SGGQEDPASQQWARPRFTQPSKMRRRVIARPVGS-SVRLKCVASGHPRPDITWMKDD--- 188

Query: 303 QPGSSYWERSSFGSVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRVVDGEWQI-VG 361
                     +    +  + +   ++L + N R ED G+Y C V+     ++  +++ V 
Sbjct: 189 ---------QALTRPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVI 239

Query: 362 ERRASTPI 369
           +R  S P+
Sbjct: 240 QRTRSKPV 247


>gi|51988912 fibroblast growth factor receptor-like 1 precursor
           [Homo sapiens]
          Length = 504

 Score = 38.9 bits (89), Expect = 0.008
 Identities = 37/155 (23%), Positives = 59/155 (38%), Gaps = 22/155 (14%)

Query: 192 FVLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVASN 251
           + L + +LR EDSGKY CRV+ R   +   +     +  ++ P++      + +V+    
Sbjct: 204 WTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVIQRTRSKPVLTGTHPVNTTVDFGGT 263

Query: 252 ASVILEGEDLRFSCSVRMAGRP--QGRFSVIWQLVDRQNRRSDIMWLDRDGTVQPGSSYW 309
            S         F C VR   +P  Q    V +    R N   D+    +   V P    W
Sbjct: 264 TS---------FQCKVRSDVKPVIQWLKRVEYGAEGRHNSTIDVG--GQKFVVLPTGDVW 312

Query: 310 ERSSFGSVQMEQVQPNSFSLGIFNSRKEDEGQYEC 344
            R     +           L I  +R++D G Y C
Sbjct: 313 SRPDGSYLN---------KLLITRARQDDAGMYIC 338



 Score = 33.9 bits (76), Expect = 0.25
 Identities = 41/188 (21%), Positives = 77/188 (40%), Gaps = 36/188 (19%)

Query: 194 LKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVL----PLESSISVEVA 249
           LK+  + +ED+G Y C+ T    +++            N  ++VL    P + S+  + +
Sbjct: 84  LKVKQVEREDAGVYVCKATNGFGSLS-----------VNYTLVVLDDISPGKESLGPDSS 132

Query: 250 SNASVILEGEDL---RFS----CSVRMAGRPQGRFSVIWQLVDRQNRRSDIMWLDRDGTV 302
           S        +     RF+       R+  RP G  SV  + V   + R DI W+  D   
Sbjct: 133 SGGQEDPASQQWARPRFTQPSKMRRRVIARPVGS-SVRLKCVASGHPRPDITWMKDD--- 188

Query: 303 QPGSSYWERSSFGSVQMEQVQPNSFSLGIFNSRKEDEGQYECHVTEWVRVVDGEWQI-VG 361
                     +    +  + +   ++L + N R ED G+Y C V+     ++  +++ V 
Sbjct: 189 ---------QALTRPEAAEPRKKKWTLSLKNLRPEDSGKYTCRVSNRAGAINATYKVDVI 239

Query: 362 ERRASTPI 369
           +R  S P+
Sbjct: 240 QRTRSKPV 247


>gi|13489095 sialoadhesin precursor [Homo sapiens]
          Length = 1709

 Score = 36.2 bits (82), Expect = 0.049
 Identities = 59/252 (23%), Positives = 90/252 (35%), Gaps = 65/252 (25%)

Query: 39  SGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQP-SDQGEFYCEAAEWIQNPDGSWYAMTR 97
           S   Y+W ++   V L+     T RL   HL   +D G ++CE    +QN  GS     R
Sbjct: 354 SDLRYSWYKN--HVLLEDAHSHTLRL---HLATRADTGFYFCE----VQNVHGS----ER 400

Query: 98  KRSEGAVVNVQPTEKEFTVRLETEKRL------HMVGEPVEFRCIPEAQNVPDRYFAVSW 151
                 VVN  P     T  LET+  L       +V EP+    +    ++       S 
Sbjct: 401 SGPVSVVVNHPPLTPVLTAFLETQAGLVGILHCSVVSEPLATLVLSHGGHILASTSGDS- 459

Query: 152 AFNSSLIATMGPNAVPVLNSEFAHREARGQLNVAKESDSVFVLKIYHLRQEDSGKYNCRV 211
             +     T GPN++                           L+I  L + DSG+Y C  
Sbjct: 460 DHSPRFSGTSGPNSLR--------------------------LEIRDLEETDSGEYKCSA 493

Query: 212 TEREKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVASNASVILEGEDLRFSCSVRMAG 271
           T      T                  L   ++ +  + S A+ ++EG+ +  SC   ++ 
Sbjct: 494 TNSLGNATS----------------TLDFHANAARLLISPAAEVVEGQAVTLSCRSGLSP 537

Query: 272 RPQGRFSVIWQL 283
            P  RFS  W L
Sbjct: 538 TPDARFS--WYL 547



 Score = 29.6 bits (65), Expect = 4.6
 Identities = 19/75 (25%), Positives = 35/75 (46%), Gaps = 1/75 (1%)

Query: 19   CKVGEKPVEVISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFY 78
            C+V  +P+  ++L     L + S+     +   + +        R+ I  L+PSDQGE+ 
Sbjct: 1554 CRVDSEPLASLTLHLGSRLVASSQPQGAPAEPHIHV-LASPNALRVDIEALRPSDQGEYI 1612

Query: 79   CEAAEWIQNPDGSWY 93
            C A+  + +   S Y
Sbjct: 1613 CSASNVLGSASTSTY 1627


>gi|27894328 interleukin 1 receptor-like 1 isoform 2 precursor [Homo
           sapiens]
          Length = 328

 Score = 35.0 bits (79), Expect = 0.11
 Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 16/97 (16%)

Query: 194 LKIYHLRQEDSGKYNCRVTEREK------TVTGEFIDKESKHPKNIPIIVLPLESSI-SV 246
           L I ++  ED+G Y C+    E       T T  F  K+ +     P+I  P ++ I  V
Sbjct: 166 LVIDNVMTEDAGDYTCKFIHNENGANYSVTATRSFTVKDEQGFSLFPVIGAPAQNEIKEV 225

Query: 247 EVASNASVILEGEDLRFSCSVRMAGRPQGRFSVIWQL 283
           E+  NA++         +CS       Q   +V+WQL
Sbjct: 226 EIGKNANL---------TCSACFGKGTQFLAAVLWQL 253


>gi|27894324 interleukin 1 receptor-like 1 isoform 1 precursor [Homo
           sapiens]
          Length = 556

 Score = 35.0 bits (79), Expect = 0.11
 Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 16/97 (16%)

Query: 194 LKIYHLRQEDSGKYNCRVTEREK------TVTGEFIDKESKHPKNIPIIVLPLESSI-SV 246
           L I ++  ED+G Y C+    E       T T  F  K+ +     P+I  P ++ I  V
Sbjct: 166 LVIDNVMTEDAGDYTCKFIHNENGANYSVTATRSFTVKDEQGFSLFPVIGAPAQNEIKEV 225

Query: 247 EVASNASVILEGEDLRFSCSVRMAGRPQGRFSVIWQL 283
           E+  NA++         +CS       Q   +V+WQL
Sbjct: 226 EIGKNANL---------TCSACFGKGTQFLAAVLWQL 253


>gi|118572606 hemicentin 1 [Homo sapiens]
          Length = 5635

 Score = 34.7 bits (78), Expect = 0.14
 Identities = 36/155 (23%), Positives = 58/155 (37%), Gaps = 41/155 (26%)

Query: 193  VLKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVASNA 252
            +LK++    ED+G+Y+C+      T    F         NI ++V P  + I     +  
Sbjct: 1415 ILKLFRATPEDAGRYSCKAINIAGTSQKYF---------NIDVLVPP--TIIGTNFPNEV 1463

Query: 253  SVILEGEDLRFSCSVRMAGRPQGRFSVIWQLVDRQNRRSDIMWLDRDGTVQPGSSYWERS 312
            SV+L   D+   C V+    P                  DI W      +  G    E  
Sbjct: 1464 SVVL-NRDVALECQVKGTPFP------------------DIHWFKDGKPLFLGDPNVELL 1504

Query: 313  SFGSVQMEQVQPNSFSLGIFNSRKEDEGQYECHVT 347
              G V           L + N+R+ D+G+Y+C V+
Sbjct: 1505 DRGQV-----------LHLKNARRNDKGRYQCTVS 1528



 Score = 31.2 bits (69), Expect = 1.6
 Identities = 37/154 (24%), Positives = 58/154 (37%), Gaps = 40/154 (25%)

Query: 194  LKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVASNAS 253
            L+I   +  DSG Y C  +           + E K  K   + +    S    E+ S+ S
Sbjct: 3209 LQIARSQHSDSGNYTCIAS-----------NMEGKAQKYYFLSIQVPPSVAGAEIPSDVS 3257

Query: 254  VILEGEDLRFSCSVRMAGRPQGRFSVIWQLVDRQNRRSDIMWLDRDGTVQPGSSYWERSS 313
            V+L GE++   C+      P                   I WL +DG  +P +S      
Sbjct: 3258 VLL-GENVELVCNANGIPTPL------------------IQWL-KDG--KPIAS------ 3289

Query: 314  FGSVQMEQVQPNSFSLGIFNSRKEDEGQYECHVT 347
             G  +  +V  N  +L I+ +   D G+Y C  T
Sbjct: 3290 -GETERIRVSANGSTLNIYGALTSDTGKYTCVAT 3322


>gi|45594240 limbic system-associated membrane protein [Homo
           sapiens]
          Length = 338

 Score = 34.7 bits (78), Expect = 0.14
 Identities = 31/116 (26%), Positives = 53/116 (45%), Gaps = 12/116 (10%)

Query: 231 KNIPIIVLPLESSISVEVASNASVILEGEDLRFSCSVRMAGRPQGRFSVIWQLVDRQNRR 290
           K +P+++L L   +   +   +     G D   + +VR     QG  +++  +V+ +N  
Sbjct: 10  KQLPLVLLRLLCLLPTGLPVRSVDFNRGTD---NITVR-----QGDTAILRCVVEDKN-- 59

Query: 291 SDIMWLDRDGTVQPGSSYWERSSFGSVQMEQVQPNSFSLGIFNSRKEDEGQYECHV 346
           S + WL+R G +  G   W  S    V++E+     +SL I      DEG Y C V
Sbjct: 60  SKVAWLNRSGIIFAGHDKW--SLDPRVELEKRHSLEYSLRIQKVDVYDEGSYTCSV 113


>gi|239753266 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 194

 Score = 34.3 bits (77), Expect = 0.19
 Identities = 22/52 (42%), Positives = 25/52 (48%), Gaps = 8/52 (15%)

Query: 271 GRPQGRFSVIWQLVD-------RQNRRSDIMWLDRDGTVQPGSSYWERSSFG 315
           G PQG F V    V         + +R    W  RDGT QPGS+ WERS  G
Sbjct: 47  GGPQGGFGVGCPRVGGAQGEGREERKRRRRWWPQRDGT-QPGSASWERSQVG 97


>gi|238624147 neuroplastin isoform c precursor [Homo sapiens]
          Length = 394

 Score = 34.3 bits (77), Expect = 0.19
 Identities = 18/41 (43%), Positives = 23/41 (56%)

Query: 176 REARGQLNVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREK 216
           R+ R  +N A  S+ V VL+I  L  EDSG Y CR +   K
Sbjct: 83  RKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYECRASNDPK 123


>gi|6912646 neuroplastin isoform b precursor [Homo sapiens]
          Length = 398

 Score = 34.3 bits (77), Expect = 0.19
 Identities = 18/41 (43%), Positives = 23/41 (56%)

Query: 176 REARGQLNVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREK 216
           R+ R  +N A  S+ V VL+I  L  EDSG Y CR +   K
Sbjct: 83  RKRRVTVNTAYGSNGVSVLRITRLTLEDSGTYECRASNDPK 123


>gi|169215606 PREDICTED: similar to immunoglobulin superfamily,
           member 3 [Homo sapiens]
          Length = 195

 Score = 33.9 bits (76), Expect = 0.25
 Identities = 22/89 (24%), Positives = 40/89 (44%), Gaps = 1/89 (1%)

Query: 257 EGEDLRFSCSVRMAGRPQGRFSVIWQLVDRQNRRSDIMWLDRDGTVQPGSSYWERSSFGS 316
           EG  +   C+V     P  + +  W +    +   ++  +    +  P + Y +R   G 
Sbjct: 97  EGSHITIWCNVSGYQGPSEQ-NFQWSIYLPSSPEREVQIVSTMDSSFPYAIYTQRVRGGK 155

Query: 317 VQMEQVQPNSFSLGIFNSRKEDEGQYECH 345
           + +E+VQ N   L I + +  D G+YECH
Sbjct: 156 IFIERVQGNPTLLHITDLQARDAGEYECH 184


>gi|239746626 PREDICTED: similar to KIAA0466 protein [Homo sapiens]
          Length = 155

 Score = 33.9 bits (76), Expect = 0.25
 Identities = 22/89 (24%), Positives = 40/89 (44%), Gaps = 1/89 (1%)

Query: 257 EGEDLRFSCSVRMAGRPQGRFSVIWQLVDRQNRRSDIMWLDRDGTVQPGSSYWERSSFGS 316
           EG  +   C+V     P  + +  W +    +   ++  +    +  P + Y +R   G 
Sbjct: 57  EGSHITIWCNVSGYQGPSEQ-NFQWSIYLPSSPEREVQIVSTMDSSFPYAIYTQRVRGGK 115

Query: 317 VQMEQVQPNSFSLGIFNSRKEDEGQYECH 345
           + +E+VQ N   L I + +  D G+YECH
Sbjct: 116 IFIERVQGNPTLLHITDLQARDAGEYECH 144


>gi|48476182 roundabout, axon guidance receptor, homolog 3 [Homo
           sapiens]
          Length = 1386

 Score = 33.9 bits (76), Expect = 0.25
 Identities = 58/257 (22%), Positives = 102/257 (39%), Gaps = 55/257 (21%)

Query: 45  WRQSLGEVRLDKLG-RTTFRLTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEGA 103
           WR+  GE+   +   R+   L I H+   D+G + C A            ++ R  + G+
Sbjct: 291 WRKEDGELPTGRYEIRSDHSLWIGHVSAEDEGTYTCVAEN----------SVGRAEASGS 340

Query: 104 V-VNVQPTEKEFTVRLETEKRLHMVGEPVEFRCIPEAQNVPDRYFAVSWAFNSSLIATMG 162
           + V+V P      +  + + ++   GE V F+C  +    P    A+ W    S +  + 
Sbjct: 341 LSVHVPP-----QLVTQPQDQMAAPGESVAFQCETKGNPPP----AIFWQKEGSQV-LLF 390

Query: 163 PNAVPVLNSEFAHREARGQLNVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKTVTGEF 222
           P+        F+    RGQLN+              +++ D+G Y C+      +V G  
Sbjct: 391 PSQSLQPTGRFS-VSPRGQLNITA------------VQRGDAGYYVCQAV----SVAGSI 433

Query: 223 IDKESKHPKNIPIIVLPLESSISVEVASNASVILEGEDLRFSCSVRMAGRPQGRFSVIWQ 282
           + K     K   +  LP    + ++  +N +++L G  +   C  R+ G PQ   SV W 
Sbjct: 434 LAKALLEIKGASLDGLP---PVILQGPANQTLVL-GSSVWLPC--RVTGNPQP--SVRW- 484

Query: 283 LVDRQNRRSDIMWLDRD 299
                  + D  WL  D
Sbjct: 485 -------KKDGQWLQGD 494


>gi|118197279 sialic acid binding Ig-like lectin 7 isoform 2 [Homo
           sapiens]
          Length = 374

 Score = 33.9 bits (76), Expect = 0.25
 Identities = 27/94 (28%), Positives = 46/94 (48%), Gaps = 8/94 (8%)

Query: 194 LKIYHLRQEDSGKYNCRVTEREKTVTGEFIDKESKH----PKNIPIIVLPLESSISVEVA 249
           L I   R  D+G+Y  R+ E+         D+ S +    P+N+ + V   E + S  + 
Sbjct: 108 LSIRDARMSDAGRYFFRM-EKGNIKWNYKYDQLSVNVTDPPQNLTVTVFQGEGTASTALG 166

Query: 250 SNASV-ILEGEDLRFSCSVRMAGRPQGRFSVIWQ 282
           +++S+ +LEG+ LR  C+V     P  R S  W+
Sbjct: 167 NSSSLSVLEGQSLRLVCAV--DSNPPARLSWTWR 198


>gi|18079321 V-set and transmembrane domain containing 2 like [Homo
           sapiens]
          Length = 204

 Score = 33.9 bits (76), Expect = 0.25
 Identities = 27/98 (27%), Positives = 43/98 (43%), Gaps = 11/98 (11%)

Query: 258 GEDLRFSCSVRMAGRPQGRFSVIWQLVDRQNRRSDIMWLDRD--GTVQPGSSYWERSSFG 315
           GED+  +CS R +G P     + W  V     RS   W D+    + Q  +S  E +   
Sbjct: 55  GEDVEMACSFRGSGSPSYSLEIQWWYV-----RSHRDWTDKQAWASNQLKASQQEDAGKE 109

Query: 316 SVQMEQVQ----PNSFSLGIFNSRKEDEGQYECHVTEW 349
           + ++  V+      S  L +   +  DEG YEC V ++
Sbjct: 110 ATKISVVKVVGSNISHKLRLSRVKPTDEGTYECRVIDF 147


>gi|254028242 fibroblast growth factor receptor 3 isoform 3
           precursor [Homo sapiens]
          Length = 808

 Score = 33.5 bits (75), Expect = 0.32
 Identities = 43/194 (22%), Positives = 73/194 (37%), Gaps = 28/194 (14%)

Query: 19  CKVGEKPVEVISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFY 78
           C     P   IS      L +G E+     +G +   KL    + L +  + PSD+G + 
Sbjct: 176 CPAAGNPTPSIS-----WLKNGREFRGEHRIGGI---KLRHQQWSLVMESVVPSDRGNYT 227

Query: 79  CEAAEWIQNPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRCIPE 138
           C     ++N  GS     R+     V+   P        L   +   ++G  VEF C   
Sbjct: 228 CV----VENKFGS----IRQTYTLDVLERSPHRPILQAGLPANQTA-VLGSDVEFHCKVY 278

Query: 139 AQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLNVAKESDSVFVLKIYH 198
           +   P   +      N S +   G   V VL S            +++  ++   L++ +
Sbjct: 279 SDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKSW-----------ISESVEADVRLRLAN 327

Query: 199 LRQEDSGKYNCRVT 212
           + + D G+Y CR T
Sbjct: 328 VSERDGGEYLCRAT 341



 Score = 28.9 bits (63), Expect = 7.9
 Identities = 13/40 (32%), Positives = 18/40 (45%)

Query: 305 GSSYWERSSFGSVQMEQVQPNSFSLGIFNSRKEDEGQYEC 344
           G + W +   G V  E+V      L + N+  ED G Y C
Sbjct: 70  GPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSC 109


>gi|4503711 fibroblast growth factor receptor 3 isoform 1 precursor
           [Homo sapiens]
          Length = 806

 Score = 33.5 bits (75), Expect = 0.32
 Identities = 45/191 (23%), Positives = 73/191 (38%), Gaps = 27/191 (14%)

Query: 19  CKVGEKPVEVISLSRDFMLHSGSEYAWRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFY 78
           C     P   IS      L +G E+     +G +   KL    + L +  + PSD+G + 
Sbjct: 176 CPAAGNPTPSIS-----WLKNGREFRGEHRIGGI---KLRHQQWSLVMESVVPSDRGNYT 227

Query: 79  CEAAEWIQNPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRCIPE 138
           C     ++N  GS     R+     V+   P        L   +   ++G  VEF C   
Sbjct: 228 CV----VENKFGS----IRQTYTLDVLERSPHRPILQAGLPANQTA-VLGSDVEFHCKVY 278

Query: 139 AQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLNVAKESDSVFVLKIYH 198
           +   P   +      N S +   G   V VL +  A+          KE +   VL +++
Sbjct: 279 SDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGAN-------TTDKELE---VLSLHN 328

Query: 199 LRQEDSGKYNC 209
           +  ED+G+Y C
Sbjct: 329 VTFEDAGEYTC 339



 Score = 28.9 bits (63), Expect = 7.9
 Identities = 13/40 (32%), Positives = 18/40 (45%)

Query: 305 GSSYWERSSFGSVQMEQVQPNSFSLGIFNSRKEDEGQYEC 344
           G + W +   G V  E+V      L + N+  ED G Y C
Sbjct: 70  GPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSC 109


>gi|7657361 contactin 6 [Homo sapiens]
          Length = 1028

 Score = 33.5 bits (75), Expect = 0.32
 Identities = 36/148 (24%), Positives = 57/148 (38%), Gaps = 32/148 (21%)

Query: 64  LTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEGAVVNVQPTEKEFTVRLETEKR 123
           L I+++  SD G + C A         +   + ++R+   V+ V P++ + TV       
Sbjct: 464 LKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERT---VITVPPSKMDVTV------- 513

Query: 124 LHMVGEPVEFRCIPEAQNVPDRYFAVSWAFNSSLIATMGPNAVPVLNSEFAHREARGQLN 183
               GE +   C  +  + P       W FN  +I          L    AH E  G   
Sbjct: 514 ----GESIVLPC--QVSHDPSIEVVFVWFFNGDVID---------LKKGVAHFERIG--- 555

Query: 184 VAKESDSVFVLKIYHLRQEDSGKYNCRV 211
                +SV  L I +++   SGKY C V
Sbjct: 556 ----GESVGDLMIRNIQLHHSGKYLCTV 579



 Score = 29.3 bits (64), Expect = 6.0
 Identities = 15/35 (42%), Positives = 20/35 (57%), Gaps = 2/35 (5%)

Query: 194 LKIYHLRQEDSGKYNCRVTEREKTV--TGEFIDKE 226
           LKIY++ + D+G Y C  T +  T   TG  I KE
Sbjct: 464 LKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKE 498


>gi|24111244 MAM domain containing glycosylphosphatidylinositol
           anchor 1 [Homo sapiens]
          Length = 955

 Score = 33.5 bits (75), Expect = 0.32
 Identities = 47/234 (20%), Positives = 86/234 (36%), Gaps = 41/234 (17%)

Query: 38  HSGSEYAWRQSLGEVRLDKLGRTTF---RLTIFHLQPSDQGEFYCEAAEWIQNPDGSWYA 94
           H   +  W ++ G    DK   T+     L I  +  +  G +YC+A   +  P      
Sbjct: 65  HPRPQVRWTKTAGSAS-DKFQETSVFNETLRIERIARTQGGRYYCKAENGVGVPAIKSIR 123

Query: 95  MTRKRSEGAVVNVQPTEKEFTVRLETEKRLHMVGEPVEFRCIPEAQNVPDRYFAVSWAFN 154
           +  +  +  ++ V  T  +       EK + +       RC   + N P R+    W   
Sbjct: 124 VDVQYLDEPMLTVHQTVSDVRGNFYQEKTVFL-------RCTVNS-NPPARFI---WKRG 172

Query: 155 SSLIATMGPNAVPVLNSEFAHREARGQLNVAKESDSVFVLKIYHLRQEDSGKYNCRVTER 214
           S  ++    N V +    +   E +             VLK+ +LR +D   Y C+V+ R
Sbjct: 173 SDTLSHSQDNGVDIYEPLYTQGETK-------------VLKLKNLRPQDYASYTCQVSVR 219

Query: 215 ------EKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVASNASV--ILEGED 260
                 +K +T    +  +      P + L +  ++ V    N +V  +L G D
Sbjct: 220 NVCGIPDKAITFRLTNTTAP-----PALKLSVNETLVVNPGENVTVQCLLTGGD 268



 Score = 32.3 bits (72), Expect = 0.71
 Identities = 35/166 (21%), Positives = 62/166 (37%), Gaps = 21/166 (12%)

Query: 148 AVSWAFNSSLIATMGPNAV---------PVLNSEFAHREARGQLNVAKESDSVFVLKIYH 198
           A+  + N +L+   G N           P+   +++H      L    +  +   L I  
Sbjct: 241 ALKLSVNETLVVNPGENVTVQCLLTGGDPLPQLQWSHGPGPLPLGALAQGGT---LSIPS 297

Query: 199 LRQEDSGKYNCRVTEREKTVTGEFIDKESKHPKNIPIIVLPLESSISVEVASNASVILEG 258
           ++  DSG YNC  T        + ++   +  KN    + P       +V   +  I  G
Sbjct: 298 VQARDSGYYNCTATNNVGNPAKKTVNLLVRSMKNATFQITP-------DVIKESENIQLG 350

Query: 259 EDLRFSCSVRMAGRPQGRFSVIWQLVDRQNRRSDIMWLDRDGTVQP 304
           +DL+ SC V     PQ + +  W    +  R S  + + R+    P
Sbjct: 351 QDLKLSCHVDAV--PQEKVTYQWFKNGKPARMSKRLLVTRNDPELP 394



 Score = 30.4 bits (67), Expect = 2.7
 Identities = 51/250 (20%), Positives = 81/250 (32%), Gaps = 50/250 (20%)

Query: 45  WRQSLGEVRLDKLGRTTFRLTIFHLQPSDQGEFYCEAAEWIQNPDGSWYAMTRKRSEGAV 104
           W    G + L  L +    L+I  +Q  D G + C A   + NP      +  +  + A 
Sbjct: 275 WSHGPGPLPLGALAQGG-TLSIPSVQARDSGYYNCTATNNVGNPAKKTVNLLVRSMKNAT 333

Query: 105 VNVQPTEKEFTVRLETEKRLHMVGEPVEFRCIPEAQNVPDRYFAVSWAFNSS-------L 157
             + P        +  E     +G+ ++  C  +A  VP       W  N         L
Sbjct: 334 FQITPD-------VIKESENIQLGQDLKLSCHVDA--VPQEKVTYQWFKNGKPARMSKRL 384

Query: 158 IATMGPNAVPVLNSEFAHREARGQLNVAKESDSVFVLKIYHLRQEDSGKYNCRVTEREKT 217
           + T     +P + S                      L++  L   D G Y C  +     
Sbjct: 385 LVTRNDPELPAVTSS---------------------LELIDLHFSDYGTYLCMASFPGAP 423

Query: 218 VTGEFIDKESKHPKNIPIIVLPLESSISVEVASNASVILEGEDLRFSCSVRMAGRPQGRF 277
           V    ++       NI    +P   +ISV        + EG      C VR   RP    
Sbjct: 424 VPDLSVE------VNISSETVP--PTISVPKGRAVVTVREGSPAELQCEVRGKPRP---- 471

Query: 278 SVIWQLVDRQ 287
            V+W  VD++
Sbjct: 472 PVLWSRVDKE 481


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,505,381
Number of Sequences: 37866
Number of extensions: 639016
Number of successful extensions: 2680
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 67
Number of HSP's that attempted gapping in prelim test: 2182
Number of HSP's gapped (non-prelim): 481
length of query: 376
length of database: 18,247,518
effective HSP length: 104
effective length of query: 272
effective length of database: 14,309,454
effective search space: 3892171488
effective search space used: 3892171488
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.