Guide to the Human Genome
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Search of human proteins with 239752750

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239752750 PREDICTED: similar to protein phosphatase 2,
catalytic subunit, alpha [Homo sapiens]
         (384 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239752750 PREDICTED: similar to protein phosphatase 2, cataly...   801   0.0  
gi|239747318 PREDICTED: similar to protein phosphatase 2, cataly...   518   e-147
gi|239741140 PREDICTED: similar to protein phosphatase 2, cataly...   518   e-147
gi|4506017 protein phosphatase 2, catalytic subunit, alpha isofo...   276   2e-74
gi|57222565 protein phosphatase 2, catalytic subunit, beta isofo...   273   1e-73
gi|4758952 protein phosphatase 2, catalytic subunit, beta isofor...   273   1e-73
gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens]    208   6e-54
gi|183603931 protein phosphatase 6, catalytic subunit isoform c ...   196   3e-50
gi|4506029 protein phosphatase 6, catalytic subunit isoform b [H...   183   2e-46
gi|183603929 protein phosphatase 6, catalytic subunit isoform a ...   182   3e-46
gi|56790945 protein phosphatase 1, catalytic subunit, alpha isof...   122   4e-28
gi|4506007 protein phosphatase 1, catalytic subunit, gamma isofo...   121   9e-28
gi|4506003 protein phosphatase 1, catalytic subunit, alpha isofo...   121   9e-28
gi|46249376 protein phosphatase 1, catalytic subunit, beta isofo...   119   6e-27
gi|4506005 protein phosphatase 1, catalytic subunit, beta isofor...   119   6e-27
gi|45827798 protein phosphatase 1, catalytic subunit, alpha isof...   108   6e-24
gi|194688149 protein phosphatase 3, catalytic subunit, alpha iso...   107   1e-23
gi|194688147 protein phosphatase 3, catalytic subunit, alpha iso...   107   1e-23
gi|6715568 protein phosphatase 3, catalytic subunit, alpha isofo...   107   1e-23
gi|215272354 protein phosphatase 3, catalytic subunit, beta isof...   102   8e-22
gi|215272352 protein phosphatase 3, catalytic subunit, beta isof...   102   8e-22
gi|11036640 protein phosphatase 3, catalytic subunit, beta isofo...   102   8e-22
gi|21361290 protein phosphatase 3, catalytic subunit, gamma [Hom...    98   1e-20
gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]     87   3e-17
gi|23312374 protein phosphatase with EF hand calcium-binding dom...    55   1e-07
gi|23312378 protein phosphatase with EF hand calcium-binding dom...    50   3e-06
gi|23312380 protein phosphatase with EF hand calcium-binding dom...    48   2e-05
gi|23312386 serine/threonine protein phosphatase with EF-hand mo...    44   3e-04
gi|122937382 Fas (TNFRSF6) binding factor 1 [Homo sapiens]             42   0.001
gi|169215850 PREDICTED: transmembrane protein 46-like [Homo sapi...    38   0.013

>gi|239752750 PREDICTED: similar to protein phosphatase 2, catalytic
           subunit, alpha [Homo sapiens]
          Length = 384

 Score =  801 bits (2068), Expect = 0.0
 Identities = 384/384 (100%), Positives = 384/384 (100%)

Query: 1   MRADAFSTMAIRGRSDVRHRGGGAIRRRAQLAPLTPARENRSPPGSLESAYLRPASDPPV 60
           MRADAFSTMAIRGRSDVRHRGGGAIRRRAQLAPLTPARENRSPPGSLESAYLRPASDPPV
Sbjct: 1   MRADAFSTMAIRGRSDVRHRGGGAIRRRAQLAPLTPARENRSPPGSLESAYLRPASDPPV 60

Query: 61  SDRAGPATRAEPRTASEQPRPHAPGSLSRRRALGCAHAERSPGVLGVAFHPMVFHCGLLA 120
           SDRAGPATRAEPRTASEQPRPHAPGSLSRRRALGCAHAERSPGVLGVAFHPMVFHCGLLA
Sbjct: 61  SDRAGPATRAEPRTASEQPRPHAPGSLSRRRALGCAHAERSPGVLGVAFHPMVFHCGLLA 120

Query: 121 VMRQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSL 180
           VMRQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSL
Sbjct: 121 VMRQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSL 180

Query: 181 CKEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVKVSYHECVTI 240
           CKEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVKVSYHECVTI
Sbjct: 181 CKEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVKVSYHECVTI 240

Query: 241 LPRNHESRQITQVYHSYEECLRKHGNANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIP 300
           LPRNHESRQITQVYHSYEECLRKHGNANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIP
Sbjct: 241 LPRNHESRQITQVYHSYEECLRKHGNANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIP 300

Query: 301 HEGPMGDLLYSDPDDHDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYC 360
           HEGPMGDLLYSDPDDHDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYC
Sbjct: 301 HEGPMGDLLYSDPDDHDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYC 360

Query: 361 YHCGGMALALQCGPPHSGELSIML 384
           YHCGGMALALQCGPPHSGELSIML
Sbjct: 361 YHCGGMALALQCGPPHSGELSIML 384


>gi|239747318 PREDICTED: similar to protein phosphatase 2, catalytic
           subunit, alpha [Homo sapiens]
          Length = 254

 Score =  518 bits (1333), Expect = e-147
 Identities = 243/243 (100%), Positives = 243/243 (100%)

Query: 122 MRQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLC 181
           MRQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLC
Sbjct: 1   MRQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLC 60

Query: 182 KEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVKVSYHECVTIL 241
           KEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVKVSYHECVTIL
Sbjct: 61  KEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVKVSYHECVTIL 120

Query: 242 PRNHESRQITQVYHSYEECLRKHGNANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPH 301
           PRNHESRQITQVYHSYEECLRKHGNANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPH
Sbjct: 121 PRNHESRQITQVYHSYEECLRKHGNANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPH 180

Query: 302 EGPMGDLLYSDPDDHDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCY 361
           EGPMGDLLYSDPDDHDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCY
Sbjct: 181 EGPMGDLLYSDPDDHDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCY 240

Query: 362 HCG 364
           HCG
Sbjct: 241 HCG 243


>gi|239741140 PREDICTED: similar to protein phosphatase 2, catalytic
           subunit, alpha [Homo sapiens]
          Length = 254

 Score =  518 bits (1333), Expect = e-147
 Identities = 243/243 (100%), Positives = 243/243 (100%)

Query: 122 MRQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLC 181
           MRQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLC
Sbjct: 1   MRQRISASGRGTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLC 60

Query: 182 KEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVKVSYHECVTIL 241
           KEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVKVSYHECVTIL
Sbjct: 61  KEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVKVSYHECVTIL 120

Query: 242 PRNHESRQITQVYHSYEECLRKHGNANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPH 301
           PRNHESRQITQVYHSYEECLRKHGNANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPH
Sbjct: 121 PRNHESRQITQVYHSYEECLRKHGNANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPH 180

Query: 302 EGPMGDLLYSDPDDHDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCY 361
           EGPMGDLLYSDPDDHDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCY
Sbjct: 181 EGPMGDLLYSDPDDHDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCY 240

Query: 362 HCG 364
           HCG
Sbjct: 241 HCG 243


>gi|4506017 protein phosphatase 2, catalytic subunit, alpha isoform
           [Homo sapiens]
          Length = 309

 Score =  276 bits (706), Expect = 2e-74
 Identities = 145/255 (56%), Positives = 166/255 (65%), Gaps = 55/255 (21%)

Query: 172 LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ--------------------- 210
           L   +VKSLC++AKEILT+ESN QEV CPVTV GD HGQ                     
Sbjct: 23  LSESQVKSLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLF 82

Query: 211 -GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNAN- 268
            GDY+DRGYYS+E V LL+A+KV Y E +TIL  NHESRQITQVY  Y+ECLRK+GNAN 
Sbjct: 83  MGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYGFYDECLRKYGNANV 142

Query: 269 ----------------GDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSD 312
                            DGQ+FCLHGGLSPS+DTL HIR L+ LQ++PHEGPM DLL+SD
Sbjct: 143 WKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSD 202

Query: 313 PDD----------------HDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFST 356
           PDD                 D  ETFNHA+GL LVSRAHQLVM G+NWCHD NVV IFS 
Sbjct: 203 PDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSA 262

Query: 357 PNYCYHCGGMALALQ 371
           PNYCY CG  A  ++
Sbjct: 263 PNYCYRCGNQAAIME 277


>gi|57222565 protein phosphatase 2, catalytic subunit, beta isoform
           [Homo sapiens]
          Length = 309

 Score =  273 bits (699), Expect = 1e-73
 Identities = 143/255 (56%), Positives = 166/255 (65%), Gaps = 55/255 (21%)

Query: 172 LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ--------------------- 210
           L   +V++LC++AKEILT+ESN QEV CPVTV GD HGQ                     
Sbjct: 23  LNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLF 82

Query: 211 -GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNAN- 268
            GDY+DRGYYS+E V LL+A+KV Y E +TIL  NHESRQITQVY  Y+ECLRK+GNAN 
Sbjct: 83  MGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANV 142

Query: 269 ----------------GDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSD 312
                            DGQ+FCLHGGLSPS+DTL HIR L+ LQ++PHEGPM DLL+SD
Sbjct: 143 WKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSD 202

Query: 313 PDD----------------HDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFST 356
           PDD                 D  ETFNHA+GL LVSRAHQLVM G+NWCHD NVV IFS 
Sbjct: 203 PDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSA 262

Query: 357 PNYCYHCGGMALALQ 371
           PNYCY CG  A  ++
Sbjct: 263 PNYCYRCGNQAAIME 277


>gi|4758952 protein phosphatase 2, catalytic subunit, beta isoform
           [Homo sapiens]
          Length = 309

 Score =  273 bits (699), Expect = 1e-73
 Identities = 143/255 (56%), Positives = 166/255 (65%), Gaps = 55/255 (21%)

Query: 172 LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ--------------------- 210
           L   +V++LC++AKEILT+ESN QEV CPVTV GD HGQ                     
Sbjct: 23  LNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLF 82

Query: 211 -GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNAN- 268
            GDY+DRGYYS+E V LL+A+KV Y E +TIL  NHESRQITQVY  Y+ECLRK+GNAN 
Sbjct: 83  MGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANV 142

Query: 269 ----------------GDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSD 312
                            DGQ+FCLHGGLSPS+DTL HIR L+ LQ++PHEGPM DLL+SD
Sbjct: 143 WKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSD 202

Query: 313 PDD----------------HDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFST 356
           PDD                 D  ETFNHA+GL LVSRAHQLVM G+NWCHD NVV IFS 
Sbjct: 203 PDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSA 262

Query: 357 PNYCYHCGGMALALQ 371
           PNYCY CG  A  ++
Sbjct: 263 PNYCYRCGNQAAIME 277


>gi|4506027 protein phosphatase 4, catalytic subunit [Homo sapiens]
          Length = 307

 Score =  208 bits (530), Expect = 6e-54
 Identities = 111/251 (44%), Positives = 150/251 (59%), Gaps = 55/251 (21%)

Query: 176 KVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDY 213
           +VK+LC +A+EIL EESN Q V  PVTV GD HGQ                      GD+
Sbjct: 24  EVKALCAKAREILVEESNVQRVDSPVTVCGDIHGQFYDLKELFRVGGDVPETNYLFMGDF 83

Query: 214 IDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHG-------- 265
           +DRG+YS+E  +LLLA+KV Y + +T++  NHESRQITQVY  Y+ECLRK+G        
Sbjct: 84  VDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYGFYDECLRKYGSVTVWRYC 143

Query: 266 ---------NANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDD- 315
                    +A  DG++FC+HGGLSPS+ TL  IRT++  Q++PH+GPM DLL+SDP+D 
Sbjct: 144 TEIFDYLSLSAIIDGKIFCVHGGLSPSIQTLDQIRTIDRKQEVPHDGPMCDLLWSDPEDT 203

Query: 316 ---------------HDTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYC 360
                           D    FN A+ + ++ RAHQLVM G+ W  +  V+ ++S PNYC
Sbjct: 204 TGWGVSPRGAGYLFGSDVVAQFNAANDIDMICRAHQLVMEGYKWHFNETVLTVWSAPNYC 263

Query: 361 YHCGGMALALQ 371
           Y CG +A  L+
Sbjct: 264 YRCGNVAAILE 274


>gi|183603931 protein phosphatase 6, catalytic subunit isoform c
           [Homo sapiens]
          Length = 283

 Score =  196 bits (498), Expect = 3e-50
 Identities = 103/229 (44%), Positives = 134/229 (58%), Gaps = 33/229 (14%)

Query: 172 LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQGDYIDRGYYSIEIVMLLLAVK 231
           L    +K LC    ++L EESN Q V  PVTV GD HGQGD++DRGYYS+E    LLA+K
Sbjct: 19  LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQGDFVDRGYYSLETFTYLLALK 78

Query: 232 VSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANG-----------------DGQLF 274
             + + +T+L  NHESRQITQVY  Y+EC  K+GNAN                  D Q+ 
Sbjct: 79  AKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQIL 138

Query: 275 CLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDDHDT---------------- 318
           C+HGGLSP + TL  IRT+   Q+IPH+G   DL++SDP+D DT                
Sbjct: 139 CVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKV 198

Query: 319 PETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCYHCGGMA 367
              F H + L+L+ RAHQLV  G+ +  D  +V ++S PNYCY CG +A
Sbjct: 199 TNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIA 247


>gi|4506029 protein phosphatase 6, catalytic subunit isoform b [Homo
           sapiens]
          Length = 305

 Score =  183 bits (465), Expect = 2e-46
 Identities = 103/251 (41%), Positives = 134/251 (53%), Gaps = 55/251 (21%)

Query: 172 LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ--------------------- 210
           L    +K LC    ++L EESN Q V  PVTV GD HGQ                     
Sbjct: 19  LPENDLKRLCDYVCDLLLEESNVQPVSTPVTVCGDIHGQFYDLCELFRTGGQVPDTNYIF 78

Query: 211 -GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANG 269
            GD++DRGYYS+E    LLA+K  + + +T+L  NHESRQITQVY  Y+EC  K+GNAN 
Sbjct: 79  MGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHESRQITQVYGFYDECQTKYGNANA 138

Query: 270 -----------------DGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSD 312
                            D Q+ C+HGGLSP + TL  IRT+   Q+IPH+G   DL++SD
Sbjct: 139 WRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQIRTIERNQEIPHKGAFCDLVWSD 198

Query: 313 PDDHDT----------------PETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFST 356
           P+D DT                   F H + L+L+ RAHQLV  G+ +  D  +V ++S 
Sbjct: 199 PEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRAHQLVHEGYKFMFDEKLVTVWSA 258

Query: 357 PNYCYHCGGMA 367
           PNYCY CG +A
Sbjct: 259 PNYCYRCGNIA 269


>gi|183603929 protein phosphatase 6, catalytic subunit isoform a
           [Homo sapiens]
          Length = 342

 Score =  182 bits (463), Expect = 3e-46
 Identities = 109/273 (39%), Positives = 140/273 (51%), Gaps = 59/273 (21%)

Query: 150 GVGSSSASLLPTPAPKAAALDGLGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHG 209
           G  +    L P P P    L  L  R    LC    ++L EESN Q V  PVTV GD HG
Sbjct: 38  GAPAGRPFLSPGPPPVFHFLRFLKER----LCDYVCDLLLEESNVQPVSTPVTVCGDIHG 93

Query: 210 Q----------------------GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHES 247
           Q                      GD++DRGYYS+E    LLA+K  + + +T+L  NHES
Sbjct: 94  QFYDLCELFRTGGQVPDTNYIFMGDFVDRGYYSLETFTYLLALKAKWPDRITLLRGNHES 153

Query: 248 RQITQVYHSYEECLRKHGNANG-----------------DGQLFCLHGGLSPSVDTLHHI 290
           RQITQVY  Y+EC  K+GNAN                  D Q+ C+HGGLSP + TL  I
Sbjct: 154 RQITQVYGFYDECQTKYGNANAWRYCTKVFDMLTVAALIDEQILCVHGGLSPDIKTLDQI 213

Query: 291 RTLNCLQKIPHEGPMGDLLYSDPDDHDT----------------PETFNHASGLRLVSRA 334
           RT+   Q+IPH+G   DL++SDP+D DT                   F H + L+L+ RA
Sbjct: 214 RTIERNQEIPHKGAFCDLVWSDPEDVDTWAISPRGAGWLFGAKVTNEFVHINNLKLICRA 273

Query: 335 HQLVMVGHNWCHDWNVVAIFSTPNYCYHCGGMA 367
           HQLV  G+ +  D  +V ++S PNYCY CG +A
Sbjct: 274 HQLVHEGYKFMFDEKLVTVWSAPNYCYRCGNIA 306


>gi|56790945 protein phosphatase 1, catalytic subunit, alpha isoform
           3 [Homo sapiens]
          Length = 341

 Score =  122 bits (307), Expect = 4e-28
 Identities = 83/265 (31%), Positives = 120/265 (45%), Gaps = 59/265 (22%)

Query: 155 SASLLPTPAPKAAALDG----LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ 210
           S  L P  AP   +  G    L   +++ LC +++EI   +    E+  P+ + GD HGQ
Sbjct: 20  SRVLTPHCAPVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQ 79

Query: 211 ----------------------GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESR 248
                                 GDY+DRG  S+E + LLLA K+ Y E   +L  NHE  
Sbjct: 80  YYDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECA 139

Query: 249 QITQVYHSYEECLRKHG----------------NANGDGQLFCLHGGLSPSVDTLHHIRT 292
            I ++Y  Y+EC R++                  A  D ++FC HGGLSP + ++  IR 
Sbjct: 140 SINRIYGFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRR 199

Query: 293 LNCLQKIPHEGPMGDLLYSDPD---------DHDTPETFN--------HASGLRLVSRAH 335
           +     +P +G + DLL+SDPD         D     TF         H   L L+ RAH
Sbjct: 200 IMRPTDVPDQGLLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAH 259

Query: 336 QLVMVGHNWCHDWNVVAIFSTPNYC 360
           Q+V  G+ +     +V +FS PNYC
Sbjct: 260 QVVEDGYEFFAKRQLVTLFSAPNYC 284


>gi|4506007 protein phosphatase 1, catalytic subunit, gamma isoform
           [Homo sapiens]
          Length = 323

 Score =  121 bits (304), Expect = 9e-28
 Identities = 77/244 (31%), Positives = 113/244 (46%), Gaps = 55/244 (22%)

Query: 172 LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ--------------------- 210
           L   +++ LC +++EI   +    E+  P+ + GD HGQ                     
Sbjct: 30  LQENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLF 89

Query: 211 -GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHG---- 265
            GDY+DRG  S+E + LLLA K+ Y E   +L  NHE   I ++Y  Y+EC R++     
Sbjct: 90  LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLW 149

Query: 266 ------------NANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDP 313
                        A  D ++FC HGGLSP + ++  IR +     +P +G + DLL+SDP
Sbjct: 150 KTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDP 209

Query: 314 D---------DHDTPETFN--------HASGLRLVSRAHQLVMVGHNWCHDWNVVAIFST 356
           D         D     TF         H   L L+ RAHQ+V  G+ +     +V +FS 
Sbjct: 210 DKDVLGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSA 269

Query: 357 PNYC 360
           PNYC
Sbjct: 270 PNYC 273


>gi|4506003 protein phosphatase 1, catalytic subunit, alpha isoform
           1 [Homo sapiens]
          Length = 330

 Score =  121 bits (304), Expect = 9e-28
 Identities = 77/244 (31%), Positives = 113/244 (46%), Gaps = 55/244 (22%)

Query: 172 LGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGDKHGQ--------------------- 210
           L   +++ LC +++EI   +    E+  P+ + GD HGQ                     
Sbjct: 30  LTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQYYDLLRLFEYGGFPPESNYLF 89

Query: 211 -GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHG---- 265
            GDY+DRG  S+E + LLLA K+ Y E   +L  NHE   I ++Y  Y+EC R++     
Sbjct: 90  LGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLW 149

Query: 266 ------------NANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDP 313
                        A  D ++FC HGGLSP + ++  IR +     +P +G + DLL+SDP
Sbjct: 150 KTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDP 209

Query: 314 D---------DHDTPETFN--------HASGLRLVSRAHQLVMVGHNWCHDWNVVAIFST 356
           D         D     TF         H   L L+ RAHQ+V  G+ +     +V +FS 
Sbjct: 210 DKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSA 269

Query: 357 PNYC 360
           PNYC
Sbjct: 270 PNYC 273


>gi|46249376 protein phosphatase 1, catalytic subunit, beta isoform
           1 [Homo sapiens]
          Length = 327

 Score =  119 bits (297), Expect = 6e-27
 Identities = 83/278 (29%), Positives = 121/278 (43%), Gaps = 58/278 (20%)

Query: 147 GSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGD 206
           G   V S    LL     +   +  +   +V+ LC +++EI   +    E+  P+ + GD
Sbjct: 4   GELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGD 63

Query: 207 KHGQ----------------------GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRN 244
            HGQ                      GDY+DRG  S+E + LLLA K+ Y E   +L  N
Sbjct: 64  IHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGN 123

Query: 245 HESRQITQVYHSYEECLRKHG----------------NANGDGQLFCLHGGLSPSVDTLH 288
           HE   I ++Y  Y+EC R+                   A  D ++FC HGGLSP + ++ 
Sbjct: 124 HECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSME 183

Query: 289 HIRTLNCLQKIPHEGPMGDLLYSDPDDH-----------------DTPETFNHASGLRLV 331
            IR +     +P  G + DLL+SDPD                   D    F +   L L+
Sbjct: 184 QIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLI 243

Query: 332 SRAHQLVMVGHNWCHDWNVVAIFSTPNYC---YHCGGM 366
            RAHQ+V  G+ +     +V +FS PNYC    + GGM
Sbjct: 244 CRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGM 281


>gi|4506005 protein phosphatase 1, catalytic subunit, beta isoform 1
           [Homo sapiens]
          Length = 327

 Score =  119 bits (297), Expect = 6e-27
 Identities = 83/278 (29%), Positives = 121/278 (43%), Gaps = 58/278 (20%)

Query: 147 GSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLCKEAKEILTEESNAQEVWCPVTVSGD 206
           G   V S    LL     +   +  +   +V+ LC +++EI   +    E+  P+ + GD
Sbjct: 4   GELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKICGD 63

Query: 207 KHGQ----------------------GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRN 244
            HGQ                      GDY+DRG  S+E + LLLA K+ Y E   +L  N
Sbjct: 64  IHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGN 123

Query: 245 HESRQITQVYHSYEECLRKHG----------------NANGDGQLFCLHGGLSPSVDTLH 288
           HE   I ++Y  Y+EC R+                   A  D ++FC HGGLSP + ++ 
Sbjct: 124 HECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSME 183

Query: 289 HIRTLNCLQKIPHEGPMGDLLYSDPDDH-----------------DTPETFNHASGLRLV 331
            IR +     +P  G + DLL+SDPD                   D    F +   L L+
Sbjct: 184 QIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDLDLI 243

Query: 332 SRAHQLVMVGHNWCHDWNVVAIFSTPNYC---YHCGGM 366
            RAHQ+V  G+ +     +V +FS PNYC    + GGM
Sbjct: 244 CRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGM 281


>gi|45827798 protein phosphatase 1, catalytic subunit, alpha isoform
           2 [Homo sapiens]
          Length = 286

 Score =  108 bits (271), Expect = 6e-24
 Identities = 65/183 (35%), Positives = 91/183 (49%), Gaps = 33/183 (18%)

Query: 211 GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHG----- 265
           GDY+DRG  S+E + LLLA K+ Y E   +L  NHE   I ++Y  Y+EC R++      
Sbjct: 47  GDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIYGFYDECKRRYNIKLWK 106

Query: 266 -----------NANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPD 314
                       A  D ++FC HGGLSP + ++  IR +     +P +G + DLL+SDPD
Sbjct: 107 TFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQGLLCDLLWSDPD 166

Query: 315 ---------DHDTPETFN--------HASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTP 357
                    D     TF         H   L L+ RAHQ+V  G+ +     +V +FS P
Sbjct: 167 KDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLVTLFSAP 226

Query: 358 NYC 360
           NYC
Sbjct: 227 NYC 229


>gi|194688149 protein phosphatase 3, catalytic subunit, alpha
           isoform isoform 3 [Homo sapiens]
          Length = 469

 Score =  107 bits (268), Expect = 1e-23
 Identities = 76/245 (31%), Positives = 108/245 (44%), Gaps = 68/245 (27%)

Query: 183 EAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDYIDRGYYS 220
           E   IL +E N  ++  PVTV GD HGQ                      GDY+DRGY+S
Sbjct: 67  EGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFS 126

Query: 221 IEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANGDG--------- 271
           IE V+ L A+K+ Y + + +L  NHE R +T+ +   +EC  K+     D          
Sbjct: 127 IECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLP 186

Query: 272 -------QLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDP----DDHDTPE 320
                  Q  C+HGGLSP ++TL  IR L+  ++ P  GPM D+L+SDP     +  T E
Sbjct: 187 LAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQE 246

Query: 321 TFNH--------------------ASGLRLVSRAHQLVMVGHNWCHDW------NVVAIF 354
            F H                     + L  + RAH+    G+            +++ IF
Sbjct: 247 HFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIF 306

Query: 355 STPNY 359
           S PNY
Sbjct: 307 SAPNY 311


>gi|194688147 protein phosphatase 3, catalytic subunit, alpha
           isoform isoform 2 [Homo sapiens]
          Length = 511

 Score =  107 bits (268), Expect = 1e-23
 Identities = 76/245 (31%), Positives = 108/245 (44%), Gaps = 68/245 (27%)

Query: 183 EAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDYIDRGYYS 220
           E   IL +E N  ++  PVTV GD HGQ                      GDY+DRGY+S
Sbjct: 67  EGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFS 126

Query: 221 IEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANGDG--------- 271
           IE V+ L A+K+ Y + + +L  NHE R +T+ +   +EC  K+     D          
Sbjct: 127 IECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLP 186

Query: 272 -------QLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDP----DDHDTPE 320
                  Q  C+HGGLSP ++TL  IR L+  ++ P  GPM D+L+SDP     +  T E
Sbjct: 187 LAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQE 246

Query: 321 TFNH--------------------ASGLRLVSRAHQLVMVGHNWCHDW------NVVAIF 354
            F H                     + L  + RAH+    G+            +++ IF
Sbjct: 247 HFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIF 306

Query: 355 STPNY 359
           S PNY
Sbjct: 307 SAPNY 311


>gi|6715568 protein phosphatase 3, catalytic subunit, alpha isoform
           isoform 1 [Homo sapiens]
          Length = 521

 Score =  107 bits (268), Expect = 1e-23
 Identities = 76/245 (31%), Positives = 108/245 (44%), Gaps = 68/245 (27%)

Query: 183 EAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDYIDRGYYS 220
           E   IL +E N  ++  PVTV GD HGQ                      GDY+DRGY+S
Sbjct: 67  EGASILRQEKNLLDIDAPVTVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFS 126

Query: 221 IEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANGDG--------- 271
           IE V+ L A+K+ Y + + +L  NHE R +T+ +   +EC  K+     D          
Sbjct: 127 IECVLYLWALKILYPKTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYDACMDAFDCLP 186

Query: 272 -------QLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDP----DDHDTPE 320
                  Q  C+HGGLSP ++TL  IR L+  ++ P  GPM D+L+SDP     +  T E
Sbjct: 187 LAALMNQQFLCVHGGLSPEINTLDDIRKLDRFKEPPAYGPMCDILWSDPLEDFGNEKTQE 246

Query: 321 TFNH--------------------ASGLRLVSRAHQLVMVGHNWCHDW------NVVAIF 354
            F H                     + L  + RAH+    G+            +++ IF
Sbjct: 247 HFTHNTVRGCSYFYSYPAVCEFLQHNNLLSILRAHEAQDAGYRMYRKSQTTGFPSLITIF 306

Query: 355 STPNY 359
           S PNY
Sbjct: 307 SAPNY 311


>gi|215272354 protein phosphatase 3, catalytic subunit, beta isoform
           c [Homo sapiens]
          Length = 515

 Score =  102 bits (253), Expect = 8e-22
 Identities = 75/248 (30%), Positives = 106/248 (42%), Gaps = 68/248 (27%)

Query: 180 LCKEAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDYIDRG 217
           +  E   IL  E    EV  P+TV GD HGQ                      GDY+DRG
Sbjct: 73  IINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRG 132

Query: 218 YYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGN----------- 266
           Y+SIE V+ L  +K+ Y   + +L  NHE R +T+ +   +EC  K+             
Sbjct: 133 YFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFD 192

Query: 267 -----ANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDD----HD 317
                A  + Q  C+HGGLSP + TL  IR L+  ++ P  GPM DLL+SDP +      
Sbjct: 193 SLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEK 252

Query: 318 TPETFNH--------------------ASGLRLVSRAHQLVMVGHNWCHDW------NVV 351
           + E F+H                     + L  + RAH+    G+            +++
Sbjct: 253 SQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLI 312

Query: 352 AIFSTPNY 359
            IFS PNY
Sbjct: 313 TIFSAPNY 320


>gi|215272352 protein phosphatase 3, catalytic subunit, beta isoform
           a [Homo sapiens]
          Length = 525

 Score =  102 bits (253), Expect = 8e-22
 Identities = 75/248 (30%), Positives = 106/248 (42%), Gaps = 68/248 (27%)

Query: 180 LCKEAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDYIDRG 217
           +  E   IL  E    EV  P+TV GD HGQ                      GDY+DRG
Sbjct: 73  IINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRG 132

Query: 218 YYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGN----------- 266
           Y+SIE V+ L  +K+ Y   + +L  NHE R +T+ +   +EC  K+             
Sbjct: 133 YFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFD 192

Query: 267 -----ANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDD----HD 317
                A  + Q  C+HGGLSP + TL  IR L+  ++ P  GPM DLL+SDP +      
Sbjct: 193 SLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEK 252

Query: 318 TPETFNH--------------------ASGLRLVSRAHQLVMVGHNWCHDW------NVV 351
           + E F+H                     + L  + RAH+    G+            +++
Sbjct: 253 SQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLI 312

Query: 352 AIFSTPNY 359
            IFS PNY
Sbjct: 313 TIFSAPNY 320


>gi|11036640 protein phosphatase 3, catalytic subunit, beta isoform
           b [Homo sapiens]
          Length = 524

 Score =  102 bits (253), Expect = 8e-22
 Identities = 75/248 (30%), Positives = 106/248 (42%), Gaps = 68/248 (27%)

Query: 180 LCKEAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDYIDRG 217
           +  E   IL  E    EV  P+TV GD HGQ                      GDY+DRG
Sbjct: 73  IINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRG 132

Query: 218 YYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGN----------- 266
           Y+SIE V+ L  +K+ Y   + +L  NHE R +T+ +   +EC  K+             
Sbjct: 133 YFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFD 192

Query: 267 -----ANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDD----HD 317
                A  + Q  C+HGGLSP + TL  IR L+  ++ P  GPM DLL+SDP +      
Sbjct: 193 SLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEK 252

Query: 318 TPETFNH--------------------ASGLRLVSRAHQLVMVGHNWCHDW------NVV 351
           + E F+H                     + L  + RAH+    G+            +++
Sbjct: 253 SQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTGFPSLI 312

Query: 352 AIFSTPNY 359
            IFS PNY
Sbjct: 313 TIFSAPNY 320


>gi|21361290 protein phosphatase 3, catalytic subunit, gamma [Homo
           sapiens]
          Length = 512

 Score = 98.2 bits (243), Expect = 1e-20
 Identities = 70/248 (28%), Positives = 107/248 (43%), Gaps = 68/248 (27%)

Query: 180 LCKEAKEILTEESNAQEVWCPVTVSGDKHGQ----------------------GDYIDRG 217
           +  +   IL +E    EV  P+TV GD HGQ                      GDY+DRG
Sbjct: 60  IINDGAAILRQEKTMIEVDAPITVCGDIHGQFFDLMKLFEVGGSPSNTRYLFLGDYVDRG 119

Query: 218 YYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANGDG------ 271
           Y+SIE V+ L ++K+++ + + +L  NHE R +T  +   +EC  K+     D       
Sbjct: 120 YFSIECVLYLWSLKINHPKTLFLLRGNHECRHLTDYFTFKQECRIKYSEQVYDACMETFD 179

Query: 272 ----------QLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDP-DDHDTPE 320
                     Q  C+HGG+SP + +L  IR L+   + P  GP+ DLL+SDP +D+   +
Sbjct: 180 CLPLAALLNQQFLCVHGGMSPEITSLDDIRKLDRFTEPPAFGPVCDLLWSDPSEDYGNEK 239

Query: 321 TFNH-----------------------ASGLRLVSRAHQLVMVGHNWCHDW------NVV 351
           T  H                        + L  + RAH+    G+            +++
Sbjct: 240 TLEHYTHNTVRGCSYFYSYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQATGFPSLI 299

Query: 352 AIFSTPNY 359
            IFS PNY
Sbjct: 300 TIFSAPNY 307


>gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]
          Length = 499

 Score = 86.7 bits (213), Expect = 3e-17
 Identities = 66/245 (26%), Positives = 101/245 (41%), Gaps = 60/245 (24%)

Query: 183 EAKEILTEESNAQEVWCP----VTVSGDKHGQ-----------------------GDYID 215
           + KE+L++ S   E        +TV GD HGQ                       GD++D
Sbjct: 215 QVKEVLSKLSTLVETTLKETEKITVCGDTHGQFYDLLNIFELNGLPSETNPYIFNGDFVD 274

Query: 216 RGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRKHGNANGD----- 270
           RG +S+E+++ L   K+ Y +   +L  NHE+  + Q+Y    E   K+     +     
Sbjct: 275 RGSFSVEVILTLFGFKLLYPDHFHLLRGNHETDNMNQIYGFEGEVKAKYTAQMYELFSEV 334

Query: 271 -----------GQLFCLHGGL-SPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPDDH-- 316
                      G++  +HGGL S    TL  IR +   ++ P  GPM DLL+SDP     
Sbjct: 335 FEWLPLAQCINGKVLIMHGGLFSEDGVTLDDIRKIERNRQPPDSGPMCDLLWSDPQPQNG 394

Query: 317 --------------DTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCYH 362
                         D  + F   + L  + R+H++   G+   H    V +FS PNYC  
Sbjct: 395 RSISKRGVSCQFGPDVTKAFLEENNLDYIIRSHEVKAEGYEVAHGGRCVTVFSAPNYCDQ 454

Query: 363 CGGMA 367
            G  A
Sbjct: 455 MGNKA 459


>gi|23312374 protein phosphatase with EF hand calcium-binding domain
           1 isoform 1b [Homo sapiens]
          Length = 625

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 62/256 (24%), Positives = 96/256 (37%), Gaps = 80/256 (31%)

Query: 183 EAKEILTEESNAQEVWCP----VTVSGDKHGQ-----------------------GDYID 215
           E K++L +  N   +       VT+ GD HG+                       GD++D
Sbjct: 145 ETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVD 204

Query: 216 RGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRK---HGN------ 266
           RG  SIEI+M+L    + Y   + +   NHE   +   Y   +E L K   HG       
Sbjct: 205 RGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQIL 264

Query: 267 ----------ANGDGQLFCLHGGLSPSVDT--LHHIRTLNCLQKI---PHE--------- 302
                        D ++  +HGG+S + D   LH +   N ++ +   P E         
Sbjct: 265 EEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRVER-NKMKSVLIPPTETNRDHDTDS 323

Query: 303 --GPMGDLLYSDPDDH-----------------DTPETFNHASGLRLVSRAHQLVMVGHN 343
               + D+L+SDP                    D      +   L+++ R+H+    G+ 
Sbjct: 324 KHNKIIDILWSDPRGKNGCFPNTCRGGGCYFGPDVTSKILNKYQLKMLIRSHECKPEGYE 383

Query: 344 WCHDWNVVAIFSTPNY 359
            CHD  VV IFS  NY
Sbjct: 384 ICHDGKVVTIFSASNY 399


>gi|23312378 protein phosphatase with EF hand calcium-binding domain
           1 isoform 3 [Homo sapiens]
          Length = 591

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 59/232 (25%), Positives = 86/232 (37%), Gaps = 66/232 (28%)

Query: 183 EAKEILTEESNAQEVWCP----VTVSGDKHGQ-----------------------GDYID 215
           E K++L +  N   +       VT+ GD HG+                       GD++D
Sbjct: 145 ETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVD 204

Query: 216 RGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRK---HG------- 265
           RG  SIEI+M+L    + Y   + +   NHE   +   Y   +E L K   HG       
Sbjct: 205 RGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQIL 264

Query: 266 ---------NANGDGQLFCLHGGLSPSVDTLHHIRTLNCLQKIPHEGPMGDLLYSDPD-- 314
                        D ++  +HGG+S + D       LN L ++     M  +L    +  
Sbjct: 265 EEFYAWLPIGTIVDNEILVIHGGISETTD-------LNLLHRV-ERNKMKSVLIPPTETN 316

Query: 315 -DHDTPETFNHASGLRLVSRAHQLVMVG-----HNWCHDW-NVVAIFSTPNY 359
            DHDT    N      +   AH  +        H   H+W  VV IFS  NY
Sbjct: 317 RDHDTDSKHNKVG---VTFNAHGRIKTNGSPTEHLTEHEWEQVVTIFSASNY 365


>gi|23312380 protein phosphatase with EF hand calcium-binding domain
           1 isoform 1 [Homo sapiens]
          Length = 653

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 63/283 (22%), Positives = 95/283 (33%), Gaps = 106/283 (37%)

Query: 183 EAKEILTEESNAQEVWCP----VTVSGDKHGQ-----------------------GDYID 215
           E K++L +  N   +       VT+ GD HG+                       GD++D
Sbjct: 145 ETKKVLKQMPNFTHIQTSPSKEVTICGDLHGKLDDLFLIFYKNGLPSERNPYVFNGDFVD 204

Query: 216 RGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRK---HG------- 265
           RG  SIEI+M+L    + Y   + +   NHE   +   Y   +E L K   HG       
Sbjct: 205 RGKNSIEILMILCVSFLVYPNDLHLNRGNHEDFMMNLRYGFTKEILHKYKLHGKRILQIL 264

Query: 266 ---------NANGDGQLFCLHGGLSPSVD--TLHHIR----------------------- 291
                        D ++  +HGG+S + D   LH +                        
Sbjct: 265 EEFYAWLPIGTIVDNEILVIHGGISETTDLNLLHRVERNKMKSVLIPPTETNRDHDTDSK 324

Query: 292 ------TLNCLQKIPHEG------------PMGDLLYSDPDDH----------------- 316
                 T N   +I   G             + D+L+SDP                    
Sbjct: 325 HNKVGVTFNAHGRIKTNGSPTEHLTEHEWEQIIDILWSDPRGKNGCFPNTCRGGGCYFGP 384

Query: 317 DTPETFNHASGLRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNY 359
           D      +   L+++ R+H+    G+  CHD  VV IFS  NY
Sbjct: 385 DVTSKILNKYQLKMLIRSHECKPEGYEICHDGKVVTIFSASNY 427


>gi|23312386 serine/threonine protein phosphatase with EF-hand
           motifs 2 [Homo sapiens]
          Length = 753

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 43/160 (26%), Positives = 62/160 (38%), Gaps = 46/160 (28%)

Query: 172 LGSRKVKSLCKEAKEILTEESNAQEVWC----PVTVSGDKHGQ----------------- 210
           L +R V +L  E K+ L +  N   V       +TV GD HGQ                 
Sbjct: 141 LHARYVLNLLYETKKHLVQLPNINRVSTCYSEEITVCGDLHGQLDDLIFIFYKNGLPSPE 200

Query: 211 ------GDYIDRGYYSIEIVMLLLAVKVSYHECVTILPRNHESRQITQVYHSYEECLRK- 263
                 GD++DRG  S+EI+M+L A  + Y +   +   NHE   +   Y   +E + K 
Sbjct: 201 RSYVFNGDFVDRGKDSVEILMILFAFMLVYPKEFHLNRGNHEDHMVNLRYGFTKEVMNKY 260

Query: 264 --HGN----------------ANGDGQLFCLHGGLSPSVD 285
             HG                    D ++  LHGG+S   D
Sbjct: 261 KVHGKEILRTLQDVFCWLPLATLIDEKVLILHGGVSDITD 300



 Score = 30.4 bits (67), Expect = 2.8
 Identities = 15/52 (28%), Positives = 26/52 (50%), Gaps = 3/52 (5%)

Query: 328 LRLVSRAHQLVMVGHNWCHDWNVVAIFSTPNYCYHCGGMALALQCGP---PH 376
           ++ + R+H+    G+ +CH+  V+ IFS  NY          ++ GP   PH
Sbjct: 481 MQFLIRSHECKPEGYEFCHNRKVLTIFSASNYYEVGSNRGAYVKLGPALTPH 532


>gi|122937382 Fas (TNFRSF6) binding factor 1 [Homo sapiens]
          Length = 1133

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 52/178 (29%), Positives = 74/178 (41%), Gaps = 16/178 (8%)

Query: 28  RAQLAPLTPARENRSPPGSLES--AYLRPASDPPVSDRAGPATRAEP----RTASEQPRP 81
           R    P+TP+     PP S  S  A L P+   P ++ AG   +A      R + E+   
Sbjct: 365 RESSVPVTPSVP---PPASQHSTPAGLPPSRAKPPTEGAGSPAKASQASKLRASKEEKED 421

Query: 82  HAPGSLSRRRALGCA---HAERSPGV--LGVAFHPMVFHCGLLAVMRQRISASG--RGTA 134
               +LSR+++ G A   HA  S G+   G A HP      L +      +A+G   GT 
Sbjct: 422 WLSHALSRKKSQGLAREQHAGTSEGLHLAGTAGHPPSGSQPLTSTQGLEHAAAGGSSGTT 481

Query: 135 AAPPWPPRRKCGGSRGVGSSSASLLPTPAPKAAALDGLGSRKVKSLCKEAKEILTEES 192
           A      R    GS    + +AS LPT +PK     G  S    + C  + +  TE S
Sbjct: 482 ARERPCVRPGVSGSPVTQNHAASALPTGSPKRGTAPGDLSATEPATCFPSTQKPTEPS 539


>gi|169215850 PREDICTED: transmembrane protein 46-like [Homo
           sapiens]
          Length = 547

 Score = 38.1 bits (87), Expect = 0.013
 Identities = 53/172 (30%), Positives = 68/172 (39%), Gaps = 19/172 (11%)

Query: 14  RSDVRHRGGGAIRRRAQLAPLTPARENRSPPGSLESAYLRPASDPPVSDRAGPATRAEPR 73
           R    +  G    R A+ +P        +PPG   +A  R +   PV    G     E R
Sbjct: 214 RGSPHNSAGPRTPRLARASPPGEPFMRVAPPGLAAAAAARDSEPGPVPGAGGCG---EDR 270

Query: 74  TASEQPRPH--APGSLSRRRALGCAHAERSPGVLGVAFHPMVFHCGLLAVMRQRISASGR 131
             S QPRP    PGS       G    +   GV      P      LLA  ++R++ + R
Sbjct: 271 LGS-QPRPENGPPGSHRTASGRGLRRGDSEGGV-NRGIGPS--RVSLLAPDKKRLNNAPR 326

Query: 132 GTAAAPPWPPRRKCGGSRGVGSSSASLLPTPAP----KAAALDGLGSRKVKS 179
           G+AA  P PPR    G R  G  S +L P  A     KAAAL     R  +S
Sbjct: 327 GSAA--PGPPR----GPRLQGGGSLTLQPDYAKYATFKAAALKAAVPRARRS 372


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.427 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,976,917
Number of Sequences: 37866
Number of extensions: 957788
Number of successful extensions: 5193
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 47
Number of HSP's successfully gapped in prelim test: 217
Number of HSP's that attempted gapping in prelim test: 4816
Number of HSP's gapped (non-prelim): 524
length of query: 384
length of database: 18,247,518
effective HSP length: 104
effective length of query: 280
effective length of database: 14,309,454
effective search space: 4006647120
effective search space used: 4006647120
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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