Guide to the Human Genome
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Name: PPP1CA Sequence: fasta or formatted (330aa) NCBI GI: 4506003
Description:

protein phosphatase 1, catalytic subunit, alpha isoform 1

Referenced in:

Myosin
Serine / Threonine Protein Phosphatases

Other entries for this name:
alt prot [286aa] protein phosphatase 1, catalytic subunit, alpha isoform 2
alt prot [341aa] protein phosphatase 1, catalytic subunit, alpha isoform 3
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.5         15           2
 C cysteine            3.9         13           2
 D aspartate           7.0         23           1
 E glutamate           6.4         21           1
 F phenylalanine       5.8         19           2
 G glycine             8.2         27           2
 H histidine           1.8          6           1
 I isoleucine          6.1         20           2
 K lysine              6.7         22           2
 L leucine            11.8         39           3
 M methionine          1.8          6           2
 N asparagine          4.5         15           1
 P proline             5.2         17           2
 Q glutamine           3.9         13           1
 R arginine            5.5         18           2
 S serine              5.5         18           1
 T threonine           2.7          9           1
 V valine              3.9         13           2
 W tryptophan          0.9          3           1
 Y tyrosine            3.9         13           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   protein phosphatase 1, catalytic subunit, alpha isofo... 
PPP1CA                0.986   protein phosphatase 1, catalytic subunit, alpha isof...
PPP1CC                0.895   protein phosphatase 1, catalytic subunit, gamma isofo...
PPP1CB                0.873   protein phosphatase 1, catalytic subunit, beta isofo...
PPP1CB                0.873   protein phosphatase 1, catalytic subunit, beta isofor...
PPP1CA                0.839   protein phosphatase 1, catalytic subunit, alpha isof...
PPP2CB                0.414   protein phosphatase 2, catalytic subunit, beta isofo...
PPP2CB                0.414   protein phosphatase 2, catalytic subunit, beta isofor...
PPP2CA                0.407   protein phosphatase 2, catalytic subunit, alpha isofo...
PPP4C                 0.404   protein phosphatase 4, catalytic subunit 
PPP6C                 0.364   protein phosphatase 6, catalytic subunit isoform b [H...
PPP6C                 0.354   protein phosphatase 6, catalytic subunit isoform a ...
PPP6C                 0.307   protein phosphatase 6, catalytic subunit isoform c ...
PPP3CA                0.303   protein phosphatase 3, catalytic subunit, alpha iso...
PPP3CA                0.303   protein phosphatase 3, catalytic subunit, alpha isofo...
PPP3CA                0.300   protein phosphatase 3, catalytic subunit, alpha iso...
PPP3CC                0.297   protein phosphatase 3, catalytic subunit, gamma [Hom...
PPP3CB                0.295   protein phosphatase 3, catalytic subunit, beta isof...
PPP3CB                0.295   protein phosphatase 3, catalytic subunit, beta isof...
PPP3CB                0.295   protein phosphatase 3, catalytic subunit, beta isofo...
PPP5C                 0.279   protein phosphatase 5, catalytic subunit 
PPEF1                 0.181   protein phosphatase with EF hand calcium-binding dom...
PPEF1                 0.166   protein phosphatase with EF hand calcium-binding dom...
LOC100128362          0.145   PREDICTED: similar to protein phosphatase 2, cataly...
LOC100128362          0.145   PREDICTED: similar to protein phosphatase 2, cataly...
LOC100128362          0.145   PREDICTED: similar to protein phosphatase 2, cataly...
PPEF2                 0.140   serine/threonine protein phosphatase with EF-hand mo...
PPEF1                 0.117   protein phosphatase with EF hand calcium-binding dom...
ZNF317                0.008   zinc finger protein 317 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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